ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI3638 good R KOG0254 General function prediction only Predicted transporter (major facilitator superfamily)
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI3638 1269082 1267370 -571
(571 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YMR088c [R] KOG0254 Predicted transporter (major facilitator sup... 509 e-144
SPBC12C2.13c [R] KOG0254 Predicted transporter (major facilitato... 161 2e-39
SPBC3E7.06c [R] KOG0254 Predicted transporter (major facilitator... 159 8e-39
YBR293w [R] KOG0254 Predicted transporter (major facilitator sup... 125 2e-28
SPBC16A3.17c [R] KOG0254 Predicted transporter (major facilitato... 84 4e-16
SPAC3H1.06c [R] KOG0254 Predicted transporter (major facilitator... 81 4e-15
SPAC1399.02 [R] KOG0254 Predicted transporter (major facilitator... 77 7e-14
YGR224w [R] KOG0254 Predicted transporter (major facilitator sup... 69 2e-11
YPR198w [R] KOG0254 Predicted transporter (major facilitator sup... 68 4e-11
YKR105c [R] KOG0254 Predicted transporter (major facilitator sup... 59 2e-08
SPCC1529.01 [R] KOG0255 Synaptic vesicle transporter SVOP and re... 55 4e-07
SPCC965.13 [R] KOG0255 Synaptic vesicle transporter SVOP and rel... 51 5e-06
YIL121w [R] KOG0255 Synaptic vesicle transporter SVOP and relate... 50 7e-06
>YMR088c [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 562
Score = 509 bits (1312), Expect = e-144
Identities = 265/545 (48%), Positives = 347/545 (63%), Gaps = 16/545 (2%)
Query: 6 DETTRLLSNRITSSSADEDDLEEMYHRHNLALPKGPILYSLWMGSFLGSLDSTIVANIMN 65
DET+ LL A+ LE+ +H +NLALPK PIL+SLW+GSFL SLDSTIVANIMN
Sbjct: 5 DETSNLLP---PPEEAEAPPLEQKFHEYNLALPKFPILFSLWLGSFLSSLDSTIVANIMN 61
Query: 66 KVAEEFEESDKKQWIVTSFLLTNTAFQPLYGKLSDLAGRKTALMVAHSFFLVGCLFTALS 125
+VAEEF ES KKQWI TSFLLTNTAFQPLYGKLSD+ GRK+AL+ A FF +GCL T +
Sbjct: 62 RVAEEFSESSKKQWIATSFLLTNTAFQPLYGKLSDITGRKSALLTAQFFFGLGCLLTCFA 121
Query: 126 RNLVEFSIARAVCXXXXXXXXXXXXXXVSDICTPKERGVYQGYANVVFGTGSMLGGPIGG 185
RN+ EFSIARA+C VSDICT +ERGVYQGYAN+VFG G +LG P+GG
Sbjct: 122 RNVTEFSIARAICGIGAGGLNAISSIAVSDICTARERGVYQGYANIVFGFGQLLGAPLGG 181
Query: 186 WLMDSFGWKVIFAGQVPLIMTCMFLGYRNVNIKLLHVPPRHERYRWENIKRIDXXXXXXX 245
+++ GW+ +F QVP+IM C L +N+NIKL HVPP ERY +N+ RID
Sbjct: 182 VFIETIGWRALFGIQVPVIMLCSVLAIKNINIKLFHVPPMKERYTLKNLSRIDIFGSLSL 241
Query: 246 XXXXXXXXCLCSTDXXXXXXXXXXXXXXXXFIMNELYWAPERIIPTDLLSGTFGITSLLT 305
LCS+ FI+ E Y+A E+I+P +LL+ +F ++S +T
Sbjct: 242 VATISGVLFLCSSQLNKLYLALFTIGSFIVFILVERYYATEKILPFELLTRSFCLSSAVT 301
Query: 306 VFSSFIAFGDVFRNPVYLQLVQNISPTXXXXXXXXXXXXXXXXXXXXXWILRNTSLGLAT 365
V SSF+ FG++FR+P+YLQL+QNIS T W+LRNT + LA
Sbjct: 302 VISSFVVFGEIFRSPIYLQLLQNISVTKTGLFLIFPSISVAVGSLVTGWVLRNTKINLAH 361
Query: 366 CSYLLITIAVCLHFISLSLGYTTISHLEPNPTSHVSALDTSGTNYWFTSNQFRWRVLYVI 425
C+Y +I + + + L LGY +SHL P+ T + + F SN W+++YV
Sbjct: 362 CAYQIIFGGMIMQLLGLGLGYFLLSHLNPDYTIYDML-----ESITFRSNSIWWKLIYVF 416
Query: 426 AMILNSWGYASLLVATLVSIVFTIPKSQQATITGCFYLWRSIGTVLGASSVLTIFESSAT 485
A +L S+GYA LLVATLVSIVFT+ KSQQ T+TG FYLWRSIG VLGAS L +E+S +
Sbjct: 417 ASVLVSFGYACLLVATLVSIVFTVEKSQQGTMTGVFYLWRSIGNVLGASLTLVSYENSLS 476
Query: 486 TKLYQYLHPINMD-------KEYESLIHDTSFLRN-HFSGKILRDLLEIYNESFLISYIP 537
+ L+ Y+ D K+Y SLI+D+S+LR +F I +L++Y ++FLISYIP
Sbjct: 477 SMLWNYMFKTKRDDEYHFTKKQYYSLINDSSYLRGPNFPTDIFVRILDVYKKAFLISYIP 536
Query: 538 TFAVS 542
A++
Sbjct: 537 NIALA 541
>SPBC12C2.13c [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 531
Score = 161 bits (408), Expect = 2e-39
Identities = 127/524 (24%), Positives = 226/524 (42%), Gaps = 56/524 (10%)
Query: 32 RHNLALPKGPILYSLWMGSFLGSLDSTIVANIMNKVAEEFEESDKKQWIVTSFLLTNTAF 91
+ L++ K IL +LW+G FL +LD TIVA++ + EF+ + +IVT++L+TNTAF
Sbjct: 23 KEELSVNKWTILPALWVGGFLSALDMTIVASLYPVIGSEFKLMNNASYIVTAYLITNTAF 82
Query: 92 QPLYGKLSDLAGRKTALMVAHSFFLVGCLFTALSRNLVEFSIARAVCXXXXXXXXXXXXX 151
QPLYG+LSD+ GR+ ++ A++ F +G + +SR+L E +ARA+
Sbjct: 83 QPLYGRLSDIFGRRPTVVFANAAFTLGTFWCGISRSLPELCMARALAGIGGGGLGTMSSI 142
Query: 152 XVSDICTPKERGVYQGYANVVFGTGSMLGGPIGGWLMDSFGWKVIFAGQVPL-IMTCMFL 210
SDI + +ERG +QG N+V+G G LGGP+GG + +GW+ F QVP+ I++ + +
Sbjct: 143 ISSDIVSLRERGTWQGITNIVWGIGGSLGGPLGGLIAQRWGWRTAFHFQVPMGILSTILV 202
Query: 211 GYRNVNIKLLHVPPRHERYRWENIKRIDXXXXXXXXXXXXXXXCLCSTDXXX---XXXXX 267
+R + V P + RID +
Sbjct: 203 AWR------VRVKPTVRNSNASLLSRIDYLGSFLLVTGITALVVTFNMGGDAFPWVSPVI 256
Query: 268 XXXXXXXXFIMNELYW-----APERIIPTDLLSGTFGITSLL-TVFSSFIAFGDVFRNPV 321
I+ YW A E I P ++LS + L F++F +F V+ P+
Sbjct: 257 ITLLVSSVLILFAFYWVEKNIAVEPIAPVEILSQPTPLNVCLGNFFNAFCSFVIVYELPL 316
Query: 322 YLQLVQNISPTXXXXXXXXXXXXXXXXXXXXXWILRNTS--LGLATCSYLLITIAVCLHF 379
+ + + + ++ T L + + + +
Sbjct: 317 FFETTLLMPSSEAGVRIFPYVISTSVGSLCSGLYMKKTGRYRNLVIAGFFFMLMGIVSFA 376
Query: 380 ISLSLGYTTISHLEPNPTSHVSALDTSGTNYWFTSNQFRWRVLYVIAMILNSWGYASLLV 439
+ S G+ T +L + + + Y L
Sbjct: 377 VLTSFGHRTP------------------------------LILISLCLAMTGCSYGMNLT 406
Query: 440 ATLVSIVFTIPKSQQATITGCFYLWRSIGTVLGASSVLTIFESSATTKLYQYLHPINMDK 499
+TL++I+ ++ +QA TG YL+R+ G+V+G S T ++ + + Q + D
Sbjct: 407 STLIAIISSLAPEEQAVATGLSYLFRATGSVIGISLSQT---TTLSILMKQLASNLKDDP 463
Query: 500 EYESLIHDTSFLRNHFS--GKILRDLLEIYNESFLISYIPTFAV 541
+ + LI LR S + +D+ ++ +S+ ++ TFA+
Sbjct: 464 DKDDLIRR---LRESISIIPNLPKDIQKLVIKSYATAFTWTFAL 504
>SPBC3E7.06c [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 577
Score = 159 bits (403), Expect = 8e-39
Identities = 140/504 (27%), Positives = 214/504 (41%), Gaps = 51/504 (10%)
Query: 42 ILYSLWMGSFLGSLDSTIVANIMNKVAEEFEESDKKQWIVTSFLLTNTAFQPLYGKLSDL 101
+L +L +G L +LD+TIVA+ K+ EF + + W T+++++ TAFQPL+GK D+
Sbjct: 91 VLPALLLGVVLAALDNTIVASTYTKIGAEFGKFSQVSWTATAYMISCTAFQPLFGKFCDI 150
Query: 102 AGRKTALMVAHSFFLVGCLFTALSRNLVEFSIARAVCXXXXXXXXXXXXXXVSDICTPKE 161
GRK L+ A+ F +GC SR+L + ARA+ +SDI K+
Sbjct: 151 YGRKKTLLAAYCVFGIGCFLCGTSRSLWQLVAARAIAGIGGGGMNSTVSILMSDIVPLKQ 210
Query: 162 RGVYQGYANVVFGTGSMLGGPIGGWLMDSFGWKVIFAGQVPLIMTCMFLGYRNVNIKLLH 221
RG YQG NV F GS LGGP+GG+ D + W++ F QVPLI Y +N+
Sbjct: 211 RGTYQGIINVFFAIGSSLGGPVGGYFADQYTWRIGFLIQVPLIAIAFLCVYFTLNL---- 266
Query: 222 VPPRHERYRW-ENIKRIDXXXXXXXXXXXXXXXCLCS--------TDXXXXXXXXXXXXX 272
P H + ++ID C + D
Sbjct: 267 --PHHNHVSFMTRFRKIDLKGLILLIIGVTTMTCAFTLGGNVREWNDPVVISLLIASSIS 324
Query: 273 XXXFIMNELYWAPERIIPTDLLSGTFGITS-LLTVFSSFIAFGDVFRNPVYLQLVQNISP 331
F+ E + A E + P D+L+ ++S L F S FG ++ P++ Q ++N
Sbjct: 325 YLSFVYVEAFVAFEPLAPMDVLTERTCLSSYLCNFFHSVANFGWIYGMPLFFQSIKN--- 381
Query: 332 TXXXXXXXXXXXXXXXXXXXXXWILRNTSLGLATCSYLLITIAVCLHFISLSLGYTTISH 391
++ +SLG L+ AV ISL+ Y I+
Sbjct: 382 -----------EGAEKSGIRLIPMIIGSSLG------SLLGGAV----ISLTGNYKKIT- 419
Query: 392 LEPNPTSHVSALDTSGTNYWFTSNQFRWRVLYVIAMILNSWGYASLLVATLVSIVFTIPK 451
+ V+AL Y + F W Y + G + TLV+I+ P
Sbjct: 420 VGSYFFGSVAALFMLRYGY----SNFNWE--YAVYPFSGGLGNGIAVTTTLVAIIHASPS 473
Query: 452 SQQATITGCFYLWRSIGTVLGASSVLTIFESSATTKLYQYLHPINMDKEYESLIHDTSF- 510
+ QA+ YL+RS G VLG S +I ++ KL + L ++D+ L D S+
Sbjct: 474 AFQASAIATSYLFRSNGCVLGVSISSSIVQTVLGIKLRKSL-DFDVDELLHHLRKDISYV 532
Query: 511 --LRNHFSGKILRDLLEIYNESFL 532
L +L LL + SFL
Sbjct: 533 HRLPEEIRQTVLDALLGSIHYSFL 556
>YBR293w [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 474
Score = 125 bits (313), Expect = 2e-28
Identities = 109/471 (23%), Positives = 190/471 (40%), Gaps = 53/471 (11%)
Query: 79 WIVTSFLLTNTAFQPLYGKLSDLAGRKTALMVAHSFFLVGCLFTALSRNLVEFSIARAVC 138
WI T++L+T+T+FQPLYG SD GR+ L A+ F +GCL S+N+ S RA+
Sbjct: 6 WITTAYLITSTSFQPLYGSFSDALGRRNCLFFANGAFTIGCLACGFSKNIYMLSFMRALT 65
Query: 139 XXXXXXXXXXXXXXVSDICTPKERGVYQGYANVVFGTGSMLGGPIGGWLMDSFGWKVIFA 198
SD+ +RG++Q + N++ G G++ G GG + S GW+ F
Sbjct: 66 GIGGGGLITLSTIVNSDVIPSSKRGIFQAFQNLLLGFGAICGASFGGTIASSIGWRWCFL 125
Query: 199 GQVPL-IMTCMFLGYRNVNIKLLHVPPRHERYRWENIKRIDXXXXXXXXXXXXXXXCL-- 255
QVP+ +++ + + Y N K + R ++N +I L
Sbjct: 126 IQVPISVISSILMNYYVPNQKEYN---RQNSSIFQNPGKILRDIDVMGSILIITGLTLQL 182
Query: 256 ------CSTDXXXXXX------XXXXXXXXXXFIMNELYWAPERIIPTDLLSGTFGITSL 303
CST FI++E + IIP +L++ ++ + L
Sbjct: 183 LYLSLGCSTSKLSWTSPSVLLLLVGSVIILLLFILHERKTSARAIIPMELVNSSYSVVVL 242
Query: 304 -LTVFSSFIAFGDVFRNPVYLQLVQNISPTXXXXXXXXXXXXXXXXXXXXXWILRNTSLG 362
+++ F ++ +F P++ Q+V S ++ S+
Sbjct: 243 SISILVGFASYAYLFTLPLFFQIVLGDSTAKAGLRLTIPSLFTPVGS-----LITGFSMS 297
Query: 363 LATCSYLLITIAVCLHFISLSLGYTTISHLEPNPTSHVSALDTSGTNYWFTSNQFRWRVL 422
C LL+ I + L F+ L + I PN W L
Sbjct: 298 KYNCLRLLLYIGISLMFLGNFL-FLFIEKTSPN---------------W----------L 331
Query: 423 YVIAMILNSWGYASLLVATLVSIVFTIPKSQQATITGCFYLWRSIGTVLGASSVLTIFES 482
+ +I + G TL + +F KS QAT T YL+RSIG+V G + + +
Sbjct: 332 IGLFLIPANLGQGITFPTTLFTFIFMFSKSDQATATSTLYLFRSIGSVWGVAISAGVIQL 391
Query: 483 SATTKLYQYLHPINMDKEYESLIHDTSFLRNHFS---GKILRDLLEIYNES 530
S L L + + + + LI S ++ G++ +++ ++E+
Sbjct: 392 SFAGLLRSNLKGLLDENKIKKLIVQLSANSSYIGSLHGEVKNTVIKSFDEA 442
>SPBC16A3.17c [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 599
Score = 84.3 bits (207), Expect = 4e-16
Identities = 48/185 (25%), Positives = 88/185 (46%), Gaps = 4/185 (2%)
Query: 18 SSSADEDDLEEMYHRHNLALPKGPILYSLWMGSFLGSLDSTIVANIMNKVAEEFEESDKK 77
S+S D+D ++ +N+ + ++ +L FL +LD+TIV + +AE+F ++
Sbjct: 78 SASNDDDTNIQLIPENNMKIVVPALILTL----FLAALDNTIVTTALPTIAEDFNDTSSS 133
Query: 78 QWIVTSFLLTNTAFQPLYGKLSDLAGRKTALMVAHSFFLVGCLFTALSRNLVEFSIARAV 137
WI ++++L + A P G ++ GRK L + FF++G S+N++ + RA+
Sbjct: 134 SWIGSAYVLASNAVLPAVGVFCNILGRKIVLYICIFFFMLGSALCGASQNMIWLIVCRAI 193
Query: 138 CXXXXXXXXXXXXXXVSDICTPKERGVYQGYANVVFGTGSMLGGPIGGWLMDSFGWKVIF 197
+SDI + R +Y G +G + G IGG + W+ IF
Sbjct: 194 QGLGGGGIISLVNIIISDITPLRTRPMYSGILATAWGAALVAGPIIGGAICQRTTWRWIF 253
Query: 198 AGQVP 202
+P
Sbjct: 254 FINLP 258
>SPAC3H1.06c [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 589
Score = 81.3 bits (199), Expect = 4e-15
Identities = 105/497 (21%), Positives = 183/497 (36%), Gaps = 60/497 (12%)
Query: 9 TRLLSNRITS--SSADEDDLEEMYHRHNLALPKGP---ILYSLWMGSFLGSLDSTIVANI 63
T L +R ++ +S+++DD + L LP ++ L + FL +LD T++
Sbjct: 58 TSSLKSRFSTHEASSEKDDSSDF----TLVLPSNRMYIVIPGLMLSIFLSALDQTVITTA 113
Query: 64 MNKVAEEFEESDKKQWIVTSFLLTNTAFQPLYGKLSDLAGRKTALMVAHSFFLVGCLFTA 123
+ + + WI T++ L T+ P G +S++ GRK L + FL G
Sbjct: 114 IPTIVANLDGGSSYSWIGTAYTLAQTSILPFCGIMSEVVGRKIVLYTSIVLFLFGSAMCG 173
Query: 124 LSRNLVEFSIARAVCXXXXXXXXXXXXXXVSDICTPKERGVYQGYANVVFGTGSMLGGPI 183
++N++ + RAV ++DI + R Y G V +G S++G I
Sbjct: 174 AAQNMLWLVLCRAVQGIGGGGITSLVTIVIADITPLQTRPYYTGCMGVTWGLASVMGPLI 233
Query: 184 GGWLMDSFGWKVIF-----AGQVPLIMTCMFLGYRNVNIKLLHVPPRHERYRWENIKRID 238
GG + W+ IF G + L + FL L+ P R + +
Sbjct: 234 GGAISQKASWRWIFFINLPTGGLSLALLIFFL-------NLVPKPTVSFRVFLRDFDFVG 286
Query: 239 XXXXXXXXXXXXXXXCLCSTDXXXXXX-----XXXXXXXXXXFIMNELYWAPERIIPTDL 293
+ ST F++NE Y RII T
Sbjct: 287 IITITTGVVLFLVGLNIGSTTGHWAHANVLCYLIFGILCIAGFVVNEFYTTRTRII-TPS 345
Query: 294 LSGTFGITSLL--TVFSSFIAFGDVFRNPVYLQLVQNISPTXXXXXXXXXXXXXXXXXXX 351
T +TS++ + +I + PVY Q ++ P
Sbjct: 346 AFKTLSLTSVMVTSFLHYYIVSTITYYIPVYFQNIKGDGPLMSGVH-------------- 391
Query: 352 XXWILRNTSLGLATCSYLLITIAVCLHFISLSLGYTTISHLEPNPTSHVSALDTSGTNYW 411
+L LA S LL ++ + +G ++ P + L +G+
Sbjct: 392 --------TLSLAVVSSLLSAVS------GMGIGKLK-NYRYPMIGGWIVLLAGTGSMIA 436
Query: 412 FTSNQFRWRVLYVIAMILNSWGYASLLVATLVSIVFTIPKSQQATITGCFYLWRSIGTVL 471
N R + +A L + G +L L+++ ++P + AT F L R++G +
Sbjct: 437 IYYNTDISRTMGFLA--LTAVGTGNLFQPNLIAVQASVPPALIATSCSAFMLLRNMGASV 494
Query: 472 GASSVLTIFESSATTKL 488
G S I++ TT L
Sbjct: 495 GISMGAVIYDQQLTTLL 511
>SPAC1399.02 [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 589
Score = 77.0 bits (188), Expect = 7e-14
Identities = 47/194 (24%), Positives = 85/194 (43%), Gaps = 4/194 (2%)
Query: 9 TRLLSNRITSSSADEDDLEEMYHRHNLALPKGPILYSLWMGSFLGSLDSTIVANIMNKVA 68
+R ++ I+S D D + + L + ++ L + FL +LD T++ + +
Sbjct: 63 SRFSTHEISSEKNDSPDFTLVLPSNRLYI----VIPGLMLSIFLAALDQTVITTAIPTIV 118
Query: 69 EEFEESDKKQWIVTSFLLTNTAFQPLYGKLSDLAGRKTALMVAHSFFLVGCLFTALSRNL 128
+ WI T++ L T+ P G +S++ GRK L + FL G ++N+
Sbjct: 119 ANLDGGSSYSWIGTAYSLAETSILPFCGIMSEVVGRKIVLYTSIVLFLFGSAMCGAAQNM 178
Query: 129 VEFSIARAVCXXXXXXXXXXXXXXVSDICTPKERGVYQGYANVVFGTGSMLGGPIGGWLM 188
+ + RAV ++DI + R Y G V +G S++G IGG +
Sbjct: 179 LWLVLCRAVQGIGGGGIMSLVTIVIADITPLQTRPYYTGCMGVTWGVASVMGPLIGGAIS 238
Query: 189 DSFGWKVIFAGQVP 202
+ W+ IF +P
Sbjct: 239 QNTTWRWIFFINLP 252
>YGR224w [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 613
Score = 68.9 bits (167), Expect = 2e-11
Identities = 46/178 (25%), Positives = 80/178 (44%), Gaps = 4/178 (2%)
Query: 37 LPKGPILYS----LWMGSFLGSLDSTIVANIMNKVAEEFEESDKKQWIVTSFLLTNTAFQ 92
LPKG ILY+ L + FL +LD IV+ I+ +VA++F + W+ T + L N
Sbjct: 60 LPKGFILYASLIALALSLFLAALDIMIVSTIIEEVAKQFGSYSEIGWLFTGYSLPNALLA 119
Query: 93 PLYGKLSDLAGRKTALMVAHSFFLVGCLFTALSRNLVEFSIARAVCXXXXXXXXXXXXXX 152
++G+++ G K ++ A F +G L +AL+ ++ R +
Sbjct: 120 LIWGRIATPIGFKETMLFAIVIFEIGSLISALANSMSMLIGGRVIAGVGGCGIQSLSFVI 179
Query: 153 VSDICTPKERGVYQGYANVVFGTGSMLGGPIGGWLMDSFGWKVIFAGQVPLIMTCMFL 210
S + +RG+ + F S++G +GG S W+ F +P+ FL
Sbjct: 180 GSTLVEESQRGILIAVLSCSFAIASVVGPFLGGVFTSSVTWRWCFYVNLPIGGLAFFL 237
>YPR198w [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 543
Score = 67.8 bits (164), Expect = 4e-11
Identities = 40/159 (25%), Positives = 70/159 (43%)
Query: 45 SLWMGSFLGSLDSTIVANIMNKVAEEFEESDKKQWIVTSFLLTNTAFQPLYGKLSDLAGR 104
SL + FL +LD IV + + + +F + W+VT + L+N F L+G+L+++ G
Sbjct: 13 SLLLTLFLAALDIVIVVTLYDTIGIKFHDFGNIGWLVTGYALSNAVFMLLWGRLAEILGT 72
Query: 105 KTALMVAHSFFLVGCLFTALSRNLVEFSIARAVCXXXXXXXXXXXXXXVSDICTPKERGV 164
K LM++ F +G L +ALS ++ R V + I RG+
Sbjct: 73 KECLMISVIVFEIGSLISALSNSMATLISGRVVAGFGGSGIESLAFVVGTSIVRENHRGI 132
Query: 165 YQGYANVVFGTGSMLGGPIGGWLMDSFGWKVIFAGQVPL 203
+ + +G IGG + W+ F +P+
Sbjct: 133 MITALAISYVIAEGVGPFIGGAFNEHLSWRWCFYINLPI 171
>YKR105c [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 582
Score = 59.3 bits (142), Expect = 2e-08
Identities = 45/179 (25%), Positives = 76/179 (42%), Gaps = 6/179 (3%)
Query: 38 PKGPILY----SLWMGSFLGSLDSTIVANIMNKVAEEFEESDKKQWIVTSFLLTNTAFQP 93
P G LY SL + F+ +LD IV I++ VAE+F K W+VT + L N
Sbjct: 31 PMGLSLYLCLASLTLVLFITALDILIVGTIIDVVAEQFGNYSKTGWLVTGYSLPNAILSL 90
Query: 94 LYGKLSDLAGRKTALMVAHSFFLVGCLFTALSRNLVEFSIARAVCXXXXXXXXXXXXXXV 153
++G+ + + G + +L++A F G L AL+ ++ R V
Sbjct: 91 IWGRFASIIGFQHSLILAILIFEAGSLIAALASSMNMLIFGRVVAGVGGSGLQTLCFVIG 150
Query: 154 SDICTPKERGVYQGYANVVFGTGSMLGGPIGGWLMDSFGWKVIFAGQVPL--IMTCMFL 210
+ + R + + F +++G IGG W+ F +P+ + MFL
Sbjct: 151 CTMVGERSRPLVISILSCAFAVAAIVGPIIGGAFTTHVTWRWCFYINLPIGGLAIIMFL 209
>SPCC1529.01 [R] KOG0255 Synaptic vesicle transporter SVOP and related
transporters (major facilitator superfamily)
Length = 462
Score = 54.7 bits (130), Expect = 4e-07
Identities = 37/150 (24%), Positives = 71/150 (46%), Gaps = 2/150 (1%)
Query: 50 SFLGSLDSTIVANIMNKVAEEF--EESDKKQWIVTSFLLTNTAFQPLYGKLSDLAGRKTA 107
+ LG + S++VA ++++A+ F + S +K I++ +LL + LS++ GR+
Sbjct: 55 ALLGPMASSMVAPCLDQIADRFHIQNSTEKALILSIYLLVFAISPMISAPLSEVFGRRML 114
Query: 108 LMVAHSFFLVGCLFTALSRNLVEFSIARAVCXXXXXXXXXXXXXXVSDICTPKERGVYQG 167
L V + F+V + L+R + I R + +SD+ TP ERG
Sbjct: 115 LQVGNVIFIVFNMACGLARTKAQMYIFRFLAGFGSATPMGLGSGTISDLFTPDERGKAVA 174
Query: 168 YANVVFGTGSMLGGPIGGWLMDSFGWKVIF 197
++ G +G + G++ + +K IF
Sbjct: 175 VMSLAPLLGPTIGPVVSGFIAEYTTYKWIF 204
>SPCC965.13 [R] KOG0255 Synaptic vesicle transporter SVOP and related
transporters (major facilitator superfamily)
Length = 537
Score = 50.8 bits (120), Expect = 5e-06
Identities = 43/169 (25%), Positives = 71/169 (41%), Gaps = 15/169 (8%)
Query: 38 PKGPILYSLWMGSFLGSL----------DSTIVANIMNKVAEEFEESDKKQWIVTSFLLT 87
P P + LW F+ ++ ST N + + S + ++V S +
Sbjct: 77 PAHPHKWPLWKKLFVATVYTFLEVYVIWSSTACINFFDIYQTNWHCSIQVSYLVQSLFIV 136
Query: 88 NTAFQP-LYGKLSDLAGRKTALMVAHSFFLVGCLFTALSRNLVEFSIARAVCXXXXXXXX 146
AF P L G +SD+ GRK + + +++ + AL+ NL +I A+
Sbjct: 137 GNAFGPMLLGPMSDIFGRKWVYVGSLILYIIFQIPQALAYNLPMMAINSAIAGAFGSSAL 196
Query: 147 XXXXXXVSDICTPKERGVYQGYANVVFG--TGSMLGGPIGGWLMDSFGW 193
+ DI TP+ G G + V+G G+ +G PIG L D + W
Sbjct: 197 ANVASSMCDIFTPETVGF--GISLFVWGANAGASIGSPIGEALYDHWRW 243
>YIL121w [R] KOG0255 Synaptic vesicle transporter SVOP and related
transporters (major facilitator superfamily)
Length = 542
Score = 50.4 bits (119), Expect = 7e-06
Identities = 39/192 (20%), Positives = 71/192 (36%), Gaps = 1/192 (0%)
Query: 7 ETTRLLSNRITSSSADEDDLEEMYHRHNLALPKGPILYSLWMGSFLGSLDSTIVANIMNK 66
ET L+ T S E ++ H K ++ F ++ I +++
Sbjct: 28 ETADKLALTRTESVKPEPEITAPPHSRFSRSFKTVLIAQCAFTGFFSTIAGAIYYPVLSV 87
Query: 67 VAEEFEESDKKQWIVTSFLLTNTAFQPLY-GKLSDLAGRKTALMVAHSFFLVGCLFTALS 125
+ +F+ ++ + P + G +D GR+ ++VA + C+ A +
Sbjct: 88 IERKFDIDEELVNVTVVVYFVFQGLAPTFMGGFADSLGRRPVVLVAIVIYFGACIGLACA 147
Query: 126 RNLVEFSIARAVCXXXXXXXXXXXXXXVSDICTPKERGVYQGYANVVFGTGSMLGGPIGG 185
+ + + R + + D+ T ERG Y GY GS G IG
Sbjct: 148 QTYAQIIVLRCLQAAGISPVIAINSGIMGDVTTRAERGGYVGYVAGFQVLGSAFGALIGA 207
Query: 186 WLMDSFGWKVIF 197
L +GW+ IF
Sbjct: 208 GLSSRWGWRAIF 219
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.323 0.137 0.419
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,595,077
Number of Sequences: 60738
Number of extensions: 1046493
Number of successful extensions: 2741
Number of sequences better than 1.0e-05: 13
Number of HSP's better than 0.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 2719
Number of HSP's gapped (non-prelim): 19
length of query: 571
length of database: 30,389,216
effective HSP length: 112
effective length of query: 459
effective length of database: 23,586,560
effective search space: 10826231040
effective search space used: 10826231040
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)