ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI3772 check: MH T KOG0198 Signal transduction mechanisms MEKK and related serine/threonine protein kinases
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI3772 1311121 1315134 1338
(1338 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YJL095w [T] KOG0198 MEKK and related serine/threonine protein ki... 843 0.0
SPAC1F3.02c [T] KOG0198 MEKK and related serine/threonine protei... 380 e-104
SPBC1D7.05c [T] KOG0198 MEKK and related serine/threonine protei... 237 8e-62
At3g06030 [T] KOG0198 MEKK and related serine/threonine protein ... 237 1e-61
At1g09000 [T] KOG0198 MEKK and related serine/threonine protein ... 237 1e-61
At1g54960 [T] KOG0198 MEKK and related serine/threonine protein ... 234 5e-61
At1g53570 [T] KOG0198 MEKK and related serine/threonine protein ... 234 9e-61
At1g63700 [T] KOG0198 MEKK and related serine/threonine protein ... 231 4e-60
YLR362w [T] KOG0198 MEKK and related serine/threonine protein ki... 229 2e-59
At5g66850 [T] KOG0198 MEKK and related serine/threonine protein ... 221 5e-57
At4g08500 [T] KOG0198 MEKK and related serine/threonine protein ... 204 1e-51
Hs4505153 [T] KOG0198 MEKK and related serine/threonine protein ... 201 5e-51
SPBC21.06c [T] KOG0198 MEKK and related serine/threonine protein... 200 1e-50
HsM5729922 [T] KOG0198 MEKK and related serine/threonine protein... 197 7e-50
Hs21735556 [T] KOG0198 MEKK and related serine/threonine protein... 196 3e-49
At4g08480 [T] KOG0198 MEKK and related serine/threonine protein ... 195 4e-49
YCR073c [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and r... 192 2e-48
At3g13530 [T] KOG0198 MEKK and related serine/threonine protein ... 192 3e-48
At4g08470 [T] KOG0198 MEKK and related serine/threonine protein ... 191 5e-48
At3g07980 [T] KOG0198 MEKK and related serine/threonine protein ... 191 7e-48
YNR031c [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and r... 190 1e-47
Hs5174547 [T] KOG4279 Serine/threonine protein kinase 186 2e-46
At4g12020_6 [T] KOG0198 MEKK and related serine/threonine protei... 184 1e-45
SPAC9G1.02 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 an... 183 1e-45
Hs22050308_2 [T] KOG0198 MEKK and related serine/threonine prote... 182 4e-45
Hs4758702 [T] KOG4279 Serine/threonine protein kinase 178 4e-44
7300559 [T] KOG4279 Serine/threonine protein kinase 176 2e-43
CE27177 [T] KOG4279 Serine/threonine protein kinase 175 5e-43
Hs6031180 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and... 171 5e-42
Hs5803088 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and... 171 5e-42
7300435 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and r... 170 2e-41
At1g69220 [T] KOG0576 Mitogen-activated protein kinase kinase ki... 165 5e-40
Hs4505599 [T] KOG0578 p21-activated serine/threonine protein kinase 162 4e-39
SPAC2C4.14c [T] KOG0201 Serine/threonine protein kinase 161 7e-39
At4g26890 [T] KOG0198 MEKK and related serine/threonine protein ... 160 1e-38
YAR019c [T] KOG0198 MEKK and related serine/threonine protein ki... 160 2e-38
SPAC9G1.09 [T] KOG0201 Serine/threonine protein kinase 159 3e-38
At5g55090 [T] KOG0198 MEKK and related serine/threonine protein ... 159 3e-38
At3g15220 [T] KOG0201 Serine/threonine protein kinase 159 4e-38
Hs5454096 [T] KOG0574 STE20-like serine/threonine kinase MST 158 6e-38
Hs15011880 [T] KOG0201 Serine/threonine protein kinase 158 6e-38
At1g53165 [T] KOG0201 Serine/threonine protein kinase 157 1e-37
YHR102w [T] KOG0201 Serine/threonine protein kinase 156 2e-37
7298926 [T] KOG0578 p21-activated serine/threonine protein kinase 156 2e-37
7300224 [T] KOG0201 Serine/threonine protein kinase 155 3e-37
Hs7382496 [T] KOG0578 p21-activated serine/threonine protein kinase 155 4e-37
Hs4505601 [T] KOG0578 p21-activated serine/threonine protein kinase 155 4e-37
Hs5454094 [T] KOG0574 STE20-like serine/threonine kinase MST 154 7e-37
Hs16178962 [T] KOG0574 STE20-like serine/threonine kinase MST 154 7e-37
YPL153c [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 154 1e-36
At1g07150 [T] KOG0198 MEKK and related serine/threonine protein ... 152 4e-36
At5g67080 [T] KOG0198 MEKK and related serine/threonine protein ... 151 6e-36
CE28674 [T] KOG0201 Serine/threonine protein kinase 151 8e-36
CE07510 [T] KOG0201 Serine/threonine protein kinase 151 8e-36
7300149 [T] KOG0578 p21-activated serine/threonine protein kinase 151 8e-36
7302511 [T] KOG0576 Mitogen-activated protein kinase kinase kina... 149 4e-35
CE27670 [T] KOG0578 p21-activated serine/threonine protein kinase 147 8e-35
Hs15451902 [T] KOG0576 Mitogen-activated protein kinase kinase k... 147 1e-34
SPAC1F5.09c [T] KOG0578 p21-activated serine/threonine protein k... 147 1e-34
HsM5454174 [T] KOG0201 Serine/threonine protein kinase 147 1e-34
Hs21361358 [T] KOG0201 Serine/threonine protein kinase 147 1e-34
At2g32510 [T] KOG0198 MEKK and related serine/threonine protein ... 147 1e-34
YHL007c [T] KOG0578 p21-activated serine/threonine protein kinase 146 2e-34
CE27965 [T] KOG0574 STE20-like serine/threonine kinase MST 146 2e-34
CE27726 [T] KOG0574 STE20-like serine/threonine kinase MST 146 2e-34
CE27082 [T] KOG0574 STE20-like serine/threonine kinase MST 146 2e-34
CE07064 [T] KOG0574 STE20-like serine/threonine kinase MST 146 2e-34
SPAC2F3.15 [D] KOG0600 Cdc2-related protein kinase 145 4e-34
Hs20070158 [T] KOG0201 Serine/threonine protein kinase 145 5e-34
SPBC1604.14c [T] KOG0578 p21-activated serine/threonine protein ... 144 9e-34
Hs14589909 [T] KOG0576 Mitogen-activated protein kinase kinase k... 144 1e-33
SPCC18B5.11c [D] KOG0615 Serine/threonine protein kinase Chk2 an... 143 2e-33
Hs14771959 [T] KOG0578 p21-activated serine/threonine protein ki... 142 3e-33
At5g14720 [T] KOG0582 Ste20-like serine/threonine protein kinase 142 4e-33
At3g50310 [T] KOG0198 MEKK and related serine/threonine protein ... 142 4e-33
Hs4826878 [T] KOG0582 Ste20-like serine/threonine protein kinase 141 6e-33
Hs9910476 [T] KOG0578 p21-activated serine/threonine protein kinase 141 8e-33
At4g29810 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 140 1e-32
Hs22035600 [T] KOG0576 Mitogen-activated protein kinase kinase k... 140 1e-32
HsM4759010 [T] KOG0576 Mitogen-activated protein kinase kinase k... 139 3e-32
CE27573 [T] KOG0198 MEKK and related serine/threonine protein ki... 138 7e-32
Hs19923464 [T] KOG0577 Serine/threonine protein kinase 137 1e-31
At2g24360 [T] KOG0192 Tyrosine kinase specific for activated (GT... 137 1e-31
7302458 [T] KOG0574 STE20-like serine/threonine kinase MST 137 1e-31
CE07737 [T] KOG0198 MEKK and related serine/threonine protein ki... 136 3e-31
7293601 [T] KOG0577 Serine/threonine protein kinase 136 3e-31
Hs5031975 [T] KOG0578 p21-activated serine/threonine protein kinase 135 4e-31
At5g40440 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 135 4e-31
At2g30040 [T] KOG0198 MEKK and related serine/threonine protein ... 134 7e-31
Hs7706401 [T] KOG0577 Serine/threonine protein kinase 134 1e-30
Hs4759208 [T] KOG0577 Serine/threonine protein kinase 134 1e-30
Hs5174701 [T] KOG0579 Ste20-like serine/threonine protein kinase 134 1e-30
Hs7019543 [T] KOG0582 Ste20-like serine/threonine protein kinase 132 4e-30
At4g10010 [D] KOG0600 Cdc2-related protein kinase 132 4e-30
YDR523c [T] KOG0201 Serine/threonine protein kinase 132 5e-30
Hs8393810_1 [T] KOG0587 Traf2- and Nck-interacting kinase and re... 132 5e-30
Hs20544910_1 [T] KOG0587 Traf2- and Nck-interacting kinase and r... 132 5e-30
At4g26070 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 131 6e-30
At2g30360 [T] KOG0583 Serine/threonine protein kinase 131 6e-30
CE07599 [T] KOG0576 Mitogen-activated protein kinase kinase kina... 131 8e-30
Hs20428779_1 [T] KOG0587 Traf2- and Nck-interacting kinase and r... 130 1e-29
At4g31170 [T] KOG0192 Tyrosine kinase specific for activated (GT... 130 1e-29
Hs7661994 [T] KOG0579 Ste20-like serine/threonine protein kinase 130 2e-29
Hs13376582 [T] KOG0198 MEKK and related serine/threonine protein... 130 2e-29
SPBC17F3.02 [T] KOG0201 Serine/threonine protein kinase 129 3e-29
At5g56580 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 129 4e-29
YOL113w [T] KOG0578 p21-activated serine/threonine protein kinase 128 5e-29
SPCC320.12c [D] KOG0580 Serine/threonine protein kinase 128 5e-29
Hs7661974 [T] KOG0583 Serine/threonine protein kinase 128 5e-29
At4g18700 [T] KOG0583 Serine/threonine protein kinase 127 1e-28
At2g34180 [T] KOG0583 Serine/threonine protein kinase 127 1e-28
At5g25110 [T] KOG0583 Serine/threonine protein kinase 127 2e-28
7292249 [T] KOG0587 Traf2- and Nck-interacting kinase and relate... 126 2e-28
YOR231w [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K) 126 3e-28
Hs4502803 [D] KOG0590 Checkpoint kinase and related serine/threo... 126 3e-28
At4g10730 [T] KOG0582 Ste20-like serine/threonine protein kinase 126 3e-28
At1g18350 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 126 3e-28
7291778 [T] KOG0579 Ste20-like serine/threonine protein kinase 126 3e-28
CE21615 [T] KOG0578 p21-activated serine/threonine protein kinase 125 3e-28
At1g50230 [R] KOG0597 Serine-threonine protein kinase FUSED 125 3e-28
CE23702 [T] KOG4721 Serine/threonine protein kinase contains leu... 125 4e-28
HsM4507279 [D] KOG0580 Serine/threonine protein kinase 125 6e-28
At1g73660 [T] KOG0192 Tyrosine kinase specific for activated (GT... 125 6e-28
At1g51660 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 125 6e-28
Hs6005810 [T] KOG0576 Mitogen-activated protein kinase kinase ki... 124 8e-28
At4g14480 [T] KOG0582 Ste20-like serine/threonine protein kinase 124 8e-28
CE26212 [T] KOG0582 Ste20-like serine/threonine protein kinase 124 1e-27
At5g50860 [D] KOG0600 Cdc2-related protein kinase 124 1e-27
At4g24100 [T] KOG0582 Ste20-like serine/threonine protein kinase 124 1e-27
At1g74330 [D] KOG0600 Cdc2-related protein kinase 124 1e-27
At2g45490 [D] KOG0580 Serine/threonine protein kinase 124 1e-27
At1g05100 [T] KOG0198 MEKK and related serine/threonine protein ... 124 1e-27
At1g01140 [T] KOG0583 Serine/threonine protein kinase 124 1e-27
YNL298w [T] KOG0578 p21-activated serine/threonine protein kinase 123 2e-27
Hs4507275 [D] KOG0580 Serine/threonine protein kinase 123 2e-27
At3g45670 [T] KOG0198 MEKK and related serine/threonine protein ... 123 2e-27
At1g04700_2 [T] KOG0192 Tyrosine kinase specific for activated (... 123 2e-27
Hs16936528 [R] KOG0594 Protein kinase PCTAIRE and related kinases 123 2e-27
CE27768 [R] KOG0586 Serine/threonine protein kinase 123 2e-27
CE23838 [R] KOG0586 Serine/threonine protein kinase 123 2e-27
At5g45810 [T] KOG0583 Serine/threonine protein kinase 123 2e-27
At3g46140 [T] KOG0198 MEKK and related serine/threonine protein ... 123 2e-27
At2g41930 [T] KOG0198 MEKK and related serine/threonine protein ... 123 2e-27
CE25046 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 122 4e-27
At4g24400 [T] KOG0583 Serine/threonine protein kinase 122 5e-27
At3g06620 [T] KOG0192 Tyrosine kinase specific for activated (GT... 122 5e-27
YPL140c [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K) 121 6e-27
Hs7657335 [T] KOG0587 Traf2- and Nck-interacting kinase and rela... 121 6e-27
At5g58950 [T] KOG0192 Tyrosine kinase specific for activated (GT... 121 6e-27
At1g62400 [T] KOG0192 Tyrosine kinase specific for activated (GT... 121 6e-27
HsM4758524 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 121 8e-27
Hs22035606 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 121 8e-27
Hs22035604 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 121 8e-27
Hs22035602 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 121 8e-27
CE26649 [D] KOG0575 Polo-like serine/threonine protein kinase 121 8e-27
At5g45820 [T] KOG0583 Serine/threonine protein kinase 121 8e-27
At1g18670 [D] KOG0600 Cdc2-related protein kinase 121 8e-27
HsM5454184 [T] KOG4721 Serine/threonine protein kinase contains ... 120 1e-26
Hs21735552 [T] KOG4721 Serine/threonine protein kinase contains ... 120 1e-26
CE28273 [T] KOG0587 Traf2- and Nck-interacting kinase and relate... 120 1e-26
CE25673 [T] KOG0587 Traf2- and Nck-interacting kinase and relate... 120 1e-26
CE25672 [T] KOG0587 Traf2- and Nck-interacting kinase and relate... 120 1e-26
CE23001 [R] KOG0589 Serine/threonine protein kinase 120 1e-26
At5g01810 [T] KOG0583 Serine/threonine protein kinase 120 1e-26
At3g45790 [T] KOG0198 MEKK and related serine/threonine protein ... 120 1e-26
At1g54610 [D] KOG0600 Cdc2-related protein kinase 120 1e-26
YKL101w [D] KOG0588 Serine/threonine protein kinase 120 2e-26
SPBC32C12.03c [T] KOG0583 Serine/threonine protein kinase 120 2e-26
HsM7657627 [D] KOG0575 Polo-like serine/threonine protein kinase 120 2e-26
At5g10930 [T] KOG0583 Serine/threonine protein kinase 120 2e-26
At1g33770 [D] KOG0600 Cdc2-related protein kinase 120 2e-26
Hs7706549 [D] KOG0600 Cdc2-related protein kinase 119 2e-26
CE24761 [D] KOG0580 Serine/threonine protein kinase 119 2e-26
At4g14580 [T] KOG0583 Serine/threonine protein kinase 119 3e-26
At2g37840 [OUT] KOG0595 Serine/threonine-protein kinase involved... 119 3e-26
7301213 [R] KOG0589 Serine/threonine protein kinase 119 3e-26
CE26422 [D] KOG0600 Cdc2-related protein kinase 119 4e-26
At1g30270 [T] KOG0583 Serine/threonine protein kinase 119 4e-26
At1g29230 [T] KOG0583 Serine/threonine protein kinase 119 4e-26
YPL203w [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 118 6e-26
At5g39420 [D] KOG0600 Cdc2-related protein kinase 118 6e-26
At2g42550 [T] KOG0198 MEKK and related serine/threonine protein ... 118 6e-26
7300106 [T] KOG0690 Serine/threonine protein kinase 118 6e-26
Hs19311016_1 [R] KOG0589 Serine/threonine protein kinase 118 6e-26
YPL209c [D] KOG0580 Serine/threonine protein kinase 118 7e-26
Hs9845489 [R] KOG0586 Serine/threonine protein kinase 118 7e-26
Hs9845487 [R] KOG0586 Serine/threonine protein kinase 118 7e-26
Hs22062450 [R] KOG0586 Serine/threonine protein kinase 118 7e-26
At3g51630 [R] KOG0584 Serine/threonine protein kinase 118 7e-26
YDR507c [D] KOG0588 Serine/threonine protein kinase 117 9e-26
SPBC4F6.06 [T] KOG0583 Serine/threonine protein kinase 117 9e-26
Hs14110390 [D] KOG0600 Cdc2-related protein kinase 117 9e-26
Hs14110387 [D] KOG0600 Cdc2-related protein kinase 117 9e-26
At2g26980 [T] KOG0583 Serine/threonine protein kinase 117 9e-26
Hs4507277_1 [R] KOG0589 Serine/threonine protein kinase 117 9e-26
At1g18160 [T] KOG0192 Tyrosine kinase specific for activated (GT... 117 1e-25
Hs21361433 [D] KOG0575 Polo-like serine/threonine protein kinase 117 2e-25
CE20564 [T] KOG0578 p21-activated serine/threonine protein kinase 117 2e-25
CE01405 [T] KOG0577 Serine/threonine protein kinase 117 2e-25
At4g30960 [T] KOG0583 Serine/threonine protein kinase 117 2e-25
At3g24720 [T] KOG0192 Tyrosine kinase specific for activated (GT... 117 2e-25
At3g06640 [T] KOG0192 Tyrosine kinase specific for activated (GT... 117 2e-25
7296451 [D] KOG0600 Cdc2-related protein kinase 117 2e-25
At3g46920_2 [T] KOG0192 Tyrosine kinase specific for activated (... 117 2e-25
YKL139w [D] KOG0600 Cdc2-related protein kinase 116 2e-25
At3g08730 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 116 2e-25
7293761 [T] KOG4721 Serine/threonine protein kinase contains leu... 116 2e-25
YCL024w [T] KOG0583 Serine/threonine protein kinase 116 3e-25
Hs4758696 [T] KOG4721 Serine/threonine protein kinase contains l... 116 3e-25
Hs7705551 [T] KOG0661 MAPK related serine/threonine protein kinase 115 4e-25
Hs7662388 [T] KOG0661 MAPK related serine/threonine protein kinase 115 4e-25
Hs18552621 [R] KOG0597 Serine-threonine protein kinase FUSED 115 4e-25
ECU01g0630 [D] KOG0575 Polo-like serine/threonine protein kinase 115 4e-25
At1g03740 [D] KOG0600 Cdc2-related protein kinase 115 4e-25
Hs5730055 [D] KOG0575 Polo-like serine/threonine protein kinase 115 5e-25
At3g61960 [OUT] KOG0595 Serine/threonine-protein kinase involved... 115 5e-25
At1g71530 [D] KOG0600 Cdc2-related protein kinase 115 5e-25
SPAC19E9.02 [D] KOG0591 NIMA (never in mitosis)-related G2-speci... 115 6e-25
CE12408 [T] KOG0661 MAPK related serine/threonine protein kinase 115 6e-25
CE05425 [T] KOG0578 p21-activated serine/threonine protein kinase 115 6e-25
At5g01820 [T] KOG0583 Serine/threonine protein kinase 115 6e-25
7298652 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 115 6e-25
Hs4758016 [D] KOG0575 Polo-like serine/threonine protein kinase 114 8e-25
Hs22068916 [T] KOG0696 Serine/threonine protein kinase 114 8e-25
Hs20149547 [T] KOG0603 Ribosomal protein S6 kinase 114 8e-25
Hs20127450 [T] KOG0696 Serine/threonine protein kinase 114 8e-25
At1g67890 [T] KOG0192 Tyrosine kinase specific for activated (GT... 114 8e-25
At1g53050 [D] KOG0600 Cdc2-related protein kinase 114 8e-25
Hs7657214 [T] KOG0583 Serine/threonine protein kinase 114 1e-24
Hs4506539 [T] KOG0192 Tyrosine kinase specific for activated (GT... 114 1e-24
Hs20479818 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 114 1e-24
At3g05050 [D] KOG0600 Cdc2-related protein kinase 114 1e-24
At1g48260 [T] KOG0583 Serine/threonine protein kinase 114 1e-24
HsM4885147 [T] KOG0201 Serine/threonine protein kinase 114 1e-24
Hs4557439 [R] KOG0594 Protein kinase PCTAIRE and related kinases 114 1e-24
Hs22035598 [T] KOG0201 Serine/threonine protein kinase 114 1e-24
Hs21359873 [D] KOG0575 Polo-like serine/threonine protein kinase 114 1e-24
ECU08g1790 [D] KOG0600 Cdc2-related protein kinase 114 1e-24
At5g11850 [T] KOG0192 Tyrosine kinase specific for activated (GT... 114 1e-24
At3g46160 [T] KOG0198 MEKK and related serine/threonine protein ... 114 1e-24
At3g08720 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 114 1e-24
At2g17890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 114 1e-24
7298323 [D] KOG0590 Checkpoint kinase and related serine/threoni... 114 1e-24
Hs8923922 [R] KOG0586 Serine/threonine protein kinase 113 2e-24
CE27297 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 113 2e-24
At3g06630 [T] KOG0192 Tyrosine kinase specific for activated (GT... 113 2e-24
At2g17700 [T] KOG0192 Tyrosine kinase specific for activated (GT... 113 2e-24
7299437 [R] KOG0586 Serine/threonine protein kinase 113 2e-24
YBR028c [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 113 2e-24
Hs4502553 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 113 2e-24
CE28251 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 113 2e-24
Hs7662210 [OUT] KOG0595 Serine/threonine-protein kinase involved... 112 3e-24
At3g21220 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 112 3e-24
7292679 [G] KOG0599 Phosphorylase kinase gamma subunit 112 3e-24
7290841 [D] KOG0591 NIMA (never in mitosis)-related G2-specific ... 112 3e-24
At2g35050_2 [T] KOG0192 Tyrosine kinase specific for activated (... 112 3e-24
YOL100w [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 112 4e-24
SPAC23C11.16 [D] KOG0575 Polo-like serine/threonine protein kinase 112 4e-24
At5g64960 [D] KOG0600 Cdc2-related protein kinase 112 4e-24
At2g34290 [T] KOG0198 MEKK and related serine/threonine protein ... 112 4e-24
At1g79570_2 [T] KOG0192 Tyrosine kinase specific for activated (... 112 4e-24
YPL031c [R] KOG0594 Protein kinase PCTAIRE and related kinases 112 5e-24
Hs7662170 [R] KOG0611 Predicted serine/threonine protein kinase 112 5e-24
Hs4507831 [OUT] KOG0595 Serine/threonine-protein kinase involved... 112 5e-24
CE29073 [R] KOG0594 Protein kinase PCTAIRE and related kinases 112 5e-24
At5g10270 [D] KOG0600 Cdc2-related protein kinase 112 5e-24
SPBC409.07c [T] KOG0581 Mitogen-activated protein kinase kinase ... 111 7e-24
Hs4826948 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 111 7e-24
At5g35410 [T] KOG0583 Serine/threonine protein kinase 111 7e-24
At4g23050 [T] KOG0192 Tyrosine kinase specific for activated (GT... 111 7e-24
At1g70430 [T] KOG0582 Ste20-like serine/threonine protein kinase 111 7e-24
HsM4505103 [R] KOG0586 Serine/threonine protein kinase 111 9e-24
Hs4759050 [T] KOG0603 Ribosomal protein S6 kinase 111 9e-24
Hs4506785 [T] KOG0660 Mitogen-activated protein kinase 111 9e-24
CE28643 [T] KOG0583 Serine/threonine protein kinase 111 9e-24
CE13014 [T] KOG0603 Ribosomal protein S6 kinase 111 9e-24
CE07458 [T] KOG0583 Serine/threonine protein kinase 111 9e-24
At5g41990 [R] KOG0584 Serine/threonine protein kinase 111 9e-24
At1g09600 [D] KOG0600 Cdc2-related protein kinase 111 9e-24
At1g08720 [T] KOG0192 Tyrosine kinase specific for activated (GT... 111 9e-24
7302464 [R] KOG0586 Serine/threonine protein kinase 111 9e-24
7297009 [R] KOG0593 Predicted protein kinase KKIAMRE 111 9e-24
At1g49180_1 [OUT] KOG0595 Serine/threonine-protein kinase involv... 111 9e-24
YJL164c [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 110 1e-23
Hs5453964 [T] KOG0583 Serine/threonine protein kinase 110 1e-23
Hs13899225 [R] KOG0586 Serine/threonine protein kinase 110 1e-23
At5g49470 [T] KOG0192 Tyrosine kinase specific for activated (GT... 110 1e-23
At5g39440 [T] KOG0583 Serine/threonine protein kinase 110 1e-23
At2g25090 [T] KOG0583 Serine/threonine protein kinase 110 1e-23
YPL141c [T] KOG0583 Serine/threonine protein kinase 110 1e-23
YMR001c [D] KOG0575 Polo-like serine/threonine protein kinase 110 1e-23
Hs4506085 [T] KOG0660 Mitogen-activated protein kinase 110 1e-23
Hs11496279 [T] KOG0661 MAPK related serine/threonine protein kinase 110 1e-23
CE28061 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 110 1e-23
CE28060 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 110 1e-23
CE28059 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 110 1e-23
CE28058 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 110 1e-23
CE28057 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 110 1e-23
CE28056 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 110 1e-23
CE28055 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 110 1e-23
CE28054 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 110 1e-23
CE28053 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 110 1e-23
CE28051 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 110 1e-23
At5g44290 [D] KOG0600 Cdc2-related protein kinase 110 1e-23
At2g38490 [T] KOG0583 Serine/threonine protein kinase 110 1e-23
YKL166c [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 110 2e-23
SPAC1B9.02c [RT] KOG0598 Ribosomal protein S6 kinase and related... 110 2e-23
Hs20536136 [T] KOG0192 Tyrosine kinase specific for activated (G... 110 2e-23
Hs14196445 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 110 2e-23
CE21879 [D] KOG0590 Checkpoint kinase and related serine/threoni... 110 2e-23
CE07285 [D] KOG0575 Polo-like serine/threonine protein kinase 110 2e-23
At5g57630 [T] KOG0583 Serine/threonine protein kinase 110 2e-23
At5g12090 [T] KOG0198 MEKK and related serine/threonine protein ... 110 2e-23
At1g66750 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 110 2e-23
Hs18602554 [T] KOG0578 p21-activated serine/threonine protein ki... 109 3e-23
Hs10835065 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 109 3e-23
7300650 [R] KOG0594 Protein kinase PCTAIRE and related kinases 109 3e-23
7299536 [D] KOG0580 Serine/threonine protein kinase 109 3e-23
Hs14735945 [T] KOG0694 Serine/threonine protein kinase 109 3e-23
CE20258 [R] KOG0593 Predicted protein kinase KKIAMRE 109 3e-23
At5g04510 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 109 3e-23
At3g17510 [T] KOG0583 Serine/threonine protein kinase 109 3e-23
At1g12580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 109 3e-23
7297680 [R] KOG0594 Protein kinase PCTAIRE and related kinases 109 3e-23
SPCC16C4.11 [R] KOG0594 Protein kinase PCTAIRE and related kinases 108 4e-23
Hs21729895 [T] KOG0581 Mitogen-activated protein kinase kinase (... 108 4e-23
ECU08g0230 [R] KOG0594 Protein kinase PCTAIRE and related kinases 108 4e-23
ECU07g0360 [D] KOG0580 Serine/threonine protein kinase 108 4e-23
CE07905 [T] KOG0579 Ste20-like serine/threonine protein kinase 108 4e-23
CE02586 [T] KOG0696 Serine/threonine protein kinase 108 4e-23
At2g41910 [T] KOG0198 MEKK and related serine/threonine protein ... 108 4e-23
YCR008w [D] KOG0590 Checkpoint kinase and related serine/threoni... 108 6e-23
HsM4826916 [D] KOG0575 Polo-like serine/threonine protein kinase 108 6e-23
Hs9966875 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 108 6e-23
Hs4758652 [R] KOG0593 Predicted protein kinase KKIAMRE 108 6e-23
Hs4757868 [T] KOG0193 Serine/threonine protein kinase RAF 108 6e-23
CE22877 [D] KOG0575 Polo-like serine/threonine protein kinase 108 6e-23
CE19294 [T] KOG0198 MEKK and related serine/threonine protein ki... 108 6e-23
At3g10540 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 108 6e-23
At1g57700 [D] KOG0600 Cdc2-related protein kinase 108 6e-23
7302860 [T] KOG0696 Serine/threonine protein kinase 108 6e-23
7296450 [D] KOG0575 Polo-like serine/threonine protein kinase 108 6e-23
At1g16270_2 [T] KOG0192 Tyrosine kinase specific for activated (... 108 6e-23
YOR233w [T] KOG0583 Serine/threonine protein kinase 108 7e-23
YFR014c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 108 7e-23
SPCC63.08c [OUT] KOG0595 Serine/threonine-protein kinase involve... 108 7e-23
Hs5453970 [T] KOG0694 Serine/threonine protein kinase 108 7e-23
Hs19424132 [D] KOG0591 NIMA (never in mitosis)-related G2-specif... 108 7e-23
CE17284 [T] KOG0583 Serine/threonine protein kinase 108 7e-23
At5g58380 [T] KOG0583 Serine/threonine protein kinase 108 7e-23
At5g42440 [T] KOG1187 Serine/threonine protein kinase 108 7e-23
At5g27510 [T] KOG0198 MEKK and related serine/threonine protein ... 108 7e-23
SPCC1259.13 [D] KOG0590 Checkpoint kinase and related serine/thr... 107 1e-22
Hs4506055 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 107 1e-22
ECU07g0520 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 107 1e-22
At4g22940 [D] KOG0600 Cdc2-related protein kinase 107 1e-22
At2g05060 [T] KOG0198 MEKK and related serine/threonine protein ... 107 1e-22
At1g07880 [T] KOG0660 Mitogen-activated protein kinase 107 1e-22
Hs5453976 [T] KOG0694 Serine/threonine protein kinase 107 1e-22
Hs5453966 [T] KOG0583 Serine/threonine protein kinase 107 1e-22
Hs4759178 [D] KOG0580 Serine/threonine protein kinase 107 1e-22
Hs4502709 [R] KOG0594 Protein kinase PCTAIRE and related kinases 107 1e-22
Hs20547878 [R] KOG0589 Serine/threonine protein kinase 107 1e-22
Hs20547806 [R] KOG0589 Serine/threonine protein kinase 107 1e-22
At4g35780 [T] KOG0192 Tyrosine kinase specific for activated (GT... 107 1e-22
At1g67580 [R] KOG0663 Protein kinase PITSLRE and related kinases 107 1e-22
SPCC162.10 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 107 2e-22
HsM4505263 [T] KOG0192 Tyrosine kinase specific for activated (G... 107 2e-22
Hs4758078 [T] KOG0197 Tyrosine kinases 107 2e-22
Hs4506067 [T] KOG0696 Serine/threonine protein kinase 107 2e-22
Hs21735550 [T] KOG0192 Tyrosine kinase specific for activated (G... 107 2e-22
Hs19923570 [T] KOG0603 Ribosomal protein S6 kinase 107 2e-22
CE21086 [D] KOG0590 Checkpoint kinase and related serine/threoni... 107 2e-22
CE20636 [D] KOG0590 Checkpoint kinase and related serine/threoni... 107 2e-22
CE18169 [T] KOG0603 Ribosomal protein S6 kinase 107 2e-22
CE15475 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 107 2e-22
CE15473 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 107 2e-22
CE00847 [T] KOG0583 Serine/threonine protein kinase 107 2e-22
At5g27790 [T] KOG0198 MEKK and related serine/threonine protein ... 107 2e-22
7293666 [D] KOG0575 Polo-like serine/threonine protein kinase 107 2e-22
7291037 [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K) 107 2e-22
At5g57610_2 [T] KOG0192 Tyrosine kinase specific for activated (... 107 2e-22
Hs5453972 [T] KOG0694 Serine/threonine protein kinase 106 2e-22
Hs4506057 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 106 2e-22
CE21401 [G] KOG0658 Glycogen synthase kinase-3 106 2e-22
At4g13020 [T] KOG0661 MAPK related serine/threonine protein kinase 106 2e-22
At3g18750 [R] KOG0584 Serine/threonine protein kinase 106 2e-22
YDR122w [T] KOG0583 Serine/threonine protein kinase 106 3e-22
Hs4505569 [R] KOG0593 Predicted protein kinase KKIAMRE 106 3e-22
CE00315 [R] KOG0594 Protein kinase PCTAIRE and related kinases 106 3e-22
At5g63370 [R] KOG0663 Protein kinase PITSLRE and related kinases 106 3e-22
At3g19100 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 106 3e-22
7290342 [G] KOG0658 Glycogen synthase kinase-3 106 3e-22
YGL158w [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 105 4e-22
SPAC890.03 [T] KOG0583 Serine/threonine protein kinase 105 4e-22
Hs7657526 [T] KOG0603 Ribosomal protein S6 kinase 105 4e-22
Hs4885583 [T] KOG0612 Rho-associated coiled-coil containing prot... 105 4e-22
Hs4885563 [T] KOG0694 Serine/threonine protein kinase 105 4e-22
Hs4505195 [T] KOG0192 Tyrosine kinase specific for activated (GT... 105 4e-22
CE06779 [R] KOG0594 Protein kinase PCTAIRE and related kinases 105 4e-22
At4g32830 [D] KOG0580 Serine/threonine protein kinase 105 4e-22
At1g73500 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 105 4e-22
7303051 [UT] KOG0662 Cyclin-dependent kinase CDK5 105 4e-22
7302908 [R] KOG0594 Protein kinase PCTAIRE and related kinases 105 4e-22
7297080 [T] KOG0583 Serine/threonine protein kinase 105 4e-22
7293496 [R] KOG0597 Serine-threonine protein kinase FUSED 105 4e-22
Hs7705748 [T] KOG0192 Tyrosine kinase specific for activated (GT... 105 5e-22
Hs4505397 [T] KOG0198 MEKK and related serine/threonine protein ... 105 5e-22
Hs4503069 [T] KOG0660 Mitogen-activated protein kinase 105 5e-22
Hs21361340 [G] KOG0658 Glycogen synthase kinase-3 105 5e-22
CE21025 [D] KOG0580 Serine/threonine protein kinase 105 5e-22
At5g58350 [R] KOG0584 Serine/threonine protein kinase 105 5e-22
At5g03730 [T] KOG0192 Tyrosine kinase specific for activated (GT... 105 5e-22
At4g40010 [T] KOG0583 Serine/threonine protein kinase 105 5e-22
At3g01090 [T] KOG0583 Serine/threonine protein kinase 105 5e-22
7302861 [T] KOG0696 Serine/threonine protein kinase 105 5e-22
7299438 [R] KOG0586 Serine/threonine protein kinase 105 5e-22
7292375 [R] KOG0594 Protein kinase PCTAIRE and related kinases 105 5e-22
HsM4504163 [G] KOG0658 Glycogen synthase kinase-3 105 6e-22
Hs4506101 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 105 6e-22
Hs4505695 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 105 6e-22
Hs21729897 [T] KOG0581 Mitogen-activated protein kinase kinase (... 105 6e-22
CE29092 [T] KOG0694 Serine/threonine protein kinase 105 6e-22
At3g48750 [R] KOG0594 Protein kinase PCTAIRE and related kinases 105 6e-22
At3g23000 [T] KOG0583 Serine/threonine protein kinase 105 6e-22
At2g35890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 105 6e-22
At1g23700 [T] KOG0582 Ste20-like serine/threonine protein kinase 105 6e-22
7290249 [R] KOG0586 Serine/threonine protein kinase 105 6e-22
7290150 [T] KOG0583 Serine/threonine protein kinase 105 6e-22
CE03080 [R] KOG0584 Serine/threonine protein kinase 104 8e-22
At3g46930 [T] KOG0192 Tyrosine kinase specific for activated (GT... 104 8e-22
At3g01490 [T] KOG0192 Tyrosine kinase specific for activated (GT... 104 8e-22
7297578 [T] KOG0661 MAPK related serine/threonine protein kinase 104 8e-22
SPAC644.06c [D] KOG0588 Serine/threonine protein kinase 104 1e-21
Hs4885549 [T] KOG0690 Serine/threonine protein kinase 104 1e-21
Hs4505785 [G] KOG0599 Phosphorylase kinase gamma subunit 104 1e-21
Hs20545245 [D] KOG0588 Serine/threonine protein kinase 104 1e-21
Hs14728804 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 104 1e-21
CE15235 [R] KOG0589 Serine/threonine protein kinase 104 1e-21
CE08098 [T] KOG0612 Rho-associated coiled-coil containing protei... 104 1e-21
CE04603 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 104 1e-21
At5g07070 [T] KOG0583 Serine/threonine protein kinase 104 1e-21
7304311 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 104 1e-21
7294265 [TR] KOG0606 Microtubule-associated serine/threonine kin... 104 1e-21
Hs4826675 [UT] KOG0662 Cyclin-dependent kinase CDK5 103 1e-21
Hs4502023 [T] KOG0690 Serine/threonine protein kinase 103 1e-21
At5g55560 [R] KOG0584 Serine/threonine protein kinase 103 1e-21
YOL016c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 103 2e-21
Hs19923407 [D] KOG0591 NIMA (never in mitosis)-related G2-specif... 103 2e-21
CE29453 [T] KOG0192 Tyrosine kinase specific for activated (GTP-... 103 2e-21
CE21213 [UT] KOG0662 Cyclin-dependent kinase CDK5 103 2e-21
CE03232 [D] KOG0591 NIMA (never in mitosis)-related G2-specific ... 103 2e-21
At5g50000 [T] KOG0192 Tyrosine kinase specific for activated (GT... 103 2e-21
At4g24480 [T] KOG0192 Tyrosine kinase specific for activated (GT... 103 2e-21
At2g43790 [T] KOG0660 Mitogen-activated protein kinase 103 2e-21
At2g41860 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 103 2e-21
7303804 [R] KOG0663 Protein kinase PITSLRE and related kinases 103 2e-21
YDR466w [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 103 2e-21
SPCC297.03 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 103 2e-21
SPACUNK12.02c [T] KOG0032 Ca2+/calmodulin-dependent protein kina... 103 2e-21
At5g04870 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 103 2e-21
At1g73690 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 103 2e-21
At1g54510 [R] KOG0589 Serine/threonine protein kinase 103 2e-21
CE26793_1 [R] KOG0611 Predicted serine/threonine protein kinase 103 2e-21
Hs5453974 [T] KOG0694 Serine/threonine protein kinase 102 3e-21
CE28218 [D] KOG0588 Serine/threonine protein kinase 102 3e-21
CE09689 [T] KOG0194 Protein tyrosine kinase 102 3e-21
At5g28290 [R] KOG0589 Serine/threonine protein kinase 102 3e-21
At5g12180 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 102 3e-21
At2g38620 [R] KOG0594 Protein kinase PCTAIRE and related kinases 102 3e-21
At2g25880 [D] KOG0580 Serine/threonine protein kinase 102 3e-21
At1g45160 [TR] KOG0606 Microtubule-associated serine/threonine k... 102 3e-21
7297542 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 102 3e-21
SPBC19F8.07 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polyme... 102 4e-21
Hs15619015 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 102 4e-21
ECU07g1270 [G] KOG0658 Glycogen synthase kinase-3 102 4e-21
CE06762 [T] KOG0660 Mitogen-activated protein kinase 102 4e-21
CE06686 [T] KOG0660 Mitogen-activated protein kinase 102 4e-21
CE06119 [T] KOG0194 Protein tyrosine kinase 102 4e-21
At3g29160 [T] KOG0583 Serine/threonine protein kinase 102 4e-21
At3g22420 [R] KOG0584 Serine/threonine protein kinase 102 4e-21
At3g04810 [R] KOG0589 Serine/threonine protein kinase 102 4e-21
7296128 [T] KOG0583 Serine/threonine protein kinase 102 4e-21
7297240_1 [T] KOG0587 Traf2- and Nck-interacting kinase and rela... 102 4e-21
YLR113w [T] KOG0660 Mitogen-activated protein kinase 102 5e-21
YDR490c [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 102 5e-21
SPAC23H4.02 [T] KOG0583 Serine/threonine protein kinase 102 5e-21
Hs4885231 [T] KOG0194 Protein tyrosine kinase 102 5e-21
Hs22065797 [T] KOG0577 Serine/threonine protein kinase 102 5e-21
Hs20986516 [T] KOG0660 Mitogen-activated protein kinase 102 5e-21
Hs20986514 [T] KOG0660 Mitogen-activated protein kinase 102 5e-21
Hs20986512 [T] KOG0660 Mitogen-activated protein kinase 102 5e-21
YHR205w [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 101 7e-21
Hs5579478 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 101 7e-21
Hs4506401 [T] KOG0193 Serine/threonine protein kinase RAF 101 7e-21
Hs4503687 [T] KOG0194 Protein tyrosine kinase 101 7e-21
Hs14776113 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 101 7e-21
CE02291 [T] KOG0194 Protein tyrosine kinase 101 7e-21
At3g49370 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 101 7e-21
YJL128c [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K) 101 9e-21
>YJL095w [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 1478
Score = 843 bits (2179), Expect = 0.0
Identities = 470/954 (49%), Positives = 605/954 (63%), Gaps = 65/954 (6%)
Query: 417 SDSRELFIMLTKDNSTFSPFNVQPHLGTDVSELKKAVALALGLTHSNFSIHLTDFGAEFG 476
+DS +I++TKDN +F P N++ +S K++ LG+ H N + H+TDF + G
Sbjct: 553 NDSENKYILVTKDNVSFVPLNLKSV--AKLSSFKESALTKLGINHKNVTFHMTDFDCDIG 610
Query: 477 SQIPDGLLADFQKTSFQNIPNKLYIQDLEKKANLNPRPRTETLXX-----XXXXXXXXXX 531
+ IPD L +K+ F N K+YI+D + K P+P T
Sbjct: 611 AAIPDDTLEFLKKSLFLNTSGKIYIKD-QMKLQQKPKPAPLTSENNVPLKSVKSKSSMRS 669
Query: 532 XXXXXXXXXXXXXXXXXXXDLTSIDDQGSSHRRAYPQTPSHYYDNSTSA----ETDYWSF 587
D+TS D+ S R YPQTPS+YYD ++ E +YW+
Sbjct: 670 GTSSLIASTDDVSIVTSSSDITSFDEHASGSGRRYPQTPSYYYDRVSNTNPTEELNYWNI 729
Query: 588 KDSVPETISDAPHITLPKSRPSLKLN----SSVLN-----THASEKSTFRIIRQTSDTDI 638
K+ + +AP + K+ P L+LN S LN T KS+F+++R+ T+I
Sbjct: 730 KEVLSHE-ENAPKMVF-KTSPKLELNLPDKGSKLNIPTPITENESKSSFQVLRKDEGTEI 787
Query: 639 DFNKRRESPYVRVAELAPKRKAPKPPVNGNPVTSGSLPSAAAKNVSESPLESPPKLDRNG 698
DFN RRESPY + ELAPKR+APKPP N +P + +S S P +L R
Sbjct: 788 DFNHRRESPYTK-PELAPKREAPKPPANTSP----------QRTLSTSKQNKPIRLVRAS 836
Query: 699 KTIYQKNKPRPPPPLTTEXXXXXXXXXXXXQDLNEVKESPVQSFTPASTQVMVPQPYKGA 758
I + + +P PP +S S+TPAST V++PQPYKGA
Sbjct: 837 TKISRSKRSKPLPPQLLSSPIEASSSS---------PDSLTSSYTPASTHVLIPQPYKGA 887
Query: 759 LETLKPRKSSAD-LSIRPRMSLRQ-FSRSNS--SLNRKVLSTSRQTLNRTNSKPLVTSST 814
+ ++ K+ D S P + ++Q +RSNS S + + + L R NSK +V+S++
Sbjct: 888 NDVMRRLKTDQDSTSTSPSLKMKQKVNRSNSTVSTSNSIFYSPSPLLKRGNSKRVVSSTS 947
Query: 815 AADIFDENDISFADAPELXXXXXX---XXXXXEIIWSRDRKSISNDVPEFSFNTEDTIDL 871
AADIF+ENDI+FADAP + +IIWS+ + + + ++ D
Sbjct: 948 AADIFEENDITFADAPPMFDSDDSDDDSSSSDDIIWSKKKTAPETNNEN---KKDEKSDN 1004
Query: 872 VGTDTTQVSVGATEGSDTPKKMALRPSPDVVYQNLEKFFPDADLDNPILEGLTXXXXXXX 931
T + ++ + +KM RPSP+VVYQNLEKFFP A+LD PI EG+
Sbjct: 1005 SSTHSDEIFYDSQTQDKMERKMTFRPSPEVVYQNLEKFFPRANLDKPITEGIASPTSPKS 1064
Query: 932 XXXXXXXRGFEKSLKTKSEQQPAFLSSRGESSQFLT--------PVKSLKPPKRTKTIRI 983
+ S S P+ S +F+ P+ K PKRTKTIR
Sbjct: 1065 LDSLLSPKNVASSRTEPST--PSRPVPPDSSYEFIQDGLNGKNKPLNQAKTPKRTKTIRT 1122
Query: 984 IAQEASEARKNEVSQKLQRKNTKMWGTKVVEITDKRTISINKSRNSRGEYKEFAWIKGEI 1043
IA EAS ARKN V KL+R+NTKMWGT++VE+T+ +SINK++NS+GEYKEFAW+KGE+
Sbjct: 1123 IAHEASLARKNSV--KLKRQNTKMWGTRMVEVTENHMVSINKAKNSKGEYKEFAWMKGEM 1180
Query: 1044 IGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHVNI 1103
IGKGSFGAVYL LNVTTGEM+AVKQV VP++SSQ+E+ +S VEAL+SEVSTLKDL+H+NI
Sbjct: 1181 IGKGSFGAVYLCLNVTTGEMMAVKQVEVPKYSSQNEAILSTVEALRSEVSTLKDLDHLNI 1240
Query: 1104 VQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHSKGIL 1163
VQYLGFE KN IYSLFLEYVAGGSVGSLIRMYGRFD+ LI+HLT QVL+GLAYLHSKGIL
Sbjct: 1241 VQYLGFENKNNIYSLFLEYVAGGSVGSLIRMYGRFDEPLIKHLTTQVLKGLAYLHSKGIL 1300
Query: 1164 HRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVDTAHGYSAK 1223
HRDMKADNLLLD DG+CKISDFGISRKS +IYSNSDMTMRGTVFWMAPEMVDT GYSAK
Sbjct: 1301 HRDMKADNLLLDQDGICKISDFGISRKSKDIYSNSDMTMRGTVFWMAPEMVDTKQGYSAK 1360
Query: 1224 VDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQSFLDQC 1283
VDIWSLGC+VLEMFAGKRPWSN EVVAAMF+IGKSK+APPIP+DT L+S G++FLD C
Sbjct: 1361 VDIWSLGCIVLEMFAGKRPWSNLEVVAAMFKIGKSKSAPPIPEDTLPLISQIGRNFLDAC 1420
Query: 1284 FEIDPEMRPTADSLVGHPFCKTSSSFDFPKTKLAQFIKSNDKLNSSRLRISSQE 1337
FEI+PE RPTA+ L+ HPF + + +F+F T+LA+FIKSNDKLNSS+LRI+SQE
Sbjct: 1421 FEINPEKRPTANELLSHPFSEVNETFNFKSTRLAKFIKSNDKLNSSKLRITSQE 1474
Score = 191 bits (486), Expect = 5e-48
Identities = 123/362 (33%), Positives = 174/362 (47%), Gaps = 27/362 (7%)
Query: 46 SGLKNDYSFDXXXXXXXXXXXXXTNSLTSERLLFNWDVTDPSQWTMPRIIQWFRANDFND 105
S KND NSL+ ++L+ +WD TDP +WTM R+ WF+ +DF +
Sbjct: 104 SSYKNDNGPSSLSDSRKSSGGNSVNSLSFDKLILSWDPTDPDEWTMHRVTSWFKFHDFPE 163
Query: 106 QWITFFKRNSISGNKFLKLLAYDNFAPYEKSLQQSKSSSYERFQYLLKKTLXXXXXXXXX 165
WI FFK++ + G++F+KLLAYDNFA YEK L Q+K++SY RFQ LLKKT+
Sbjct: 164 SWILFFKKHQLFGHRFIKLLAYDNFAVYEKYLPQTKTASYTRFQQLLKKTMTKNVTNSHI 223
Query: 166 XXXXXXXXXXXXXXXXXXXXQRLSTSFSTHI---RSTSESALLNIENITKDSSSSEPTTS 222
+ ++ I RSTSESAL S ++ S
Sbjct: 224 RQKSASKLKSSRSSSESIKSKLKNSKSQEDISNSRSTSESAL----------SPTKSGPS 273
Query: 223 KKQEASNYSLPLRQAKTNSASALYRRSLISLRNASSTKDNASK--NDIKITIPPRPLXXX 280
K E + KT SAS+LYRRS ISLR +SS+ +++K ++IK++IP RP
Sbjct: 274 KTDEKNFLHSTSTHQKTKSASSLYRRSFISLRGSSSSNASSAKSPSNIKLSIPARP--HS 331
Query: 281 XXXXXXXXXXXXXXXXXXAYTGIFRRQHKTXXXXXXLFTSIFGHGVVEEPEETPKPR--P 338
+Y IFRR HK+ L S+FG G+ EE P P+
Sbjct: 332 IIESNSTLTKSASPPASPSYPSIFRRHHKSSSSESSLLNSLFGSGIGEEAPTKPNPQGHS 391
Query: 339 VENRRIPAASTVNASTS-----KQSI--NVDDKARLWDKIKRKGQLPAEPSSQPAARIII 391
+ + + + + T+ KQS DDK LW+K KRK Q+ PS A +
Sbjct: 392 LSSENLAKGKSKHYETNVSSPLKQSSLPTSDDKGNLWNKFKRKSQI-GVPSPNTVAYVTS 450
Query: 392 EE 393
+E
Sbjct: 451 QE 452
>SPAC1F3.02c [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 1116
Score = 380 bits (975), Expect = e-104
Identities = 224/604 (37%), Positives = 333/604 (55%), Gaps = 121/604 (20%)
Query: 787 SSLNRKVLSTSRQTLNRTNSKPLV------------------TSSTAADIFDEN-----D 823
SSL RK T R ++ S P + SS +++ E+ +
Sbjct: 551 SSLRRKNTLTRRPSIRHARSSPYIDTGHNEASKFSHTSFDPKASSKSSNSLKESVEALSE 610
Query: 824 ISFADAPELXXXXXXXXXXXEIIWSRDRKSISNDVPE---------FSFNTEDTIDLVGT 874
I F DAP L + W+ K S+ VP+ S NTE DL
Sbjct: 611 IPFEDAPALDESDLSG----DPFWAIQPKQSSSQVPKENHHNIQSKLSINTEAATDLKAN 666
Query: 875 DTTQVSVGA-TEGSDTPKKMA----------------------------LRPSPDVVYQN 905
+ + G D ++ +RPS D +Y++
Sbjct: 667 ELSSPKTPEYCRGDDRSISLSPLSYRLRKSKHIRESPPSSKVINSGNWEVRPSADDLYED 726
Query: 906 LEKFFPDADLDNPILEGLTXXXXXXXXXXXXXXRGFEKSLKTKSEQQPAFLSSRGESSQF 965
+++FFP DLD ++ +S
Sbjct: 727 VDRFFPRYDLDKVLVVD--------------------------------------QSRMV 748
Query: 966 LTPVK-SLKPPKRTKTIRIIAQEASEARK--------NEVSQKLQRKNTKMWGTKVVEIT 1016
+P K S++P + K++R++A+EASEARK N+ L+R +TK+WG+++VE+
Sbjct: 749 SSPSKVSIRP--KMKSVRLLAREASEARKEIRHNARRNKSGNLLRRSSTKLWGSRIVELK 806
Query: 1017 DKRTISINKSRNSRGEYKEFAWIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSS 1076
TI+ + +K W+KGE+IG G++G V+LA+N+ TGE++AVKQV +P+ +
Sbjct: 807 PDTTITSGSVVSQNATFK---WMKGELIGNGTYGKVFLAMNINTGELIAVKQVEIPQTIN 863
Query: 1077 --QDESAISMVEALKSEVSTLKDLNHVNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRM 1134
D+ +V+++ +E+S + DL+H+NIVQYLGFE+ S+FLEYV+GGS+G +R
Sbjct: 864 GRHDQLRKDIVDSINAEISMIADLDHLNIVQYLGFEKTETDISIFLEYVSGGSIGRCLRN 923
Query: 1135 YGRFDDQLIRHLTKQVLEGLAYLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNI 1194
YG F++QL+R +++QVL GL+YLHSKGI+HRD+KADNLL+D DGVCKISDFGIS+ S+N+
Sbjct: 924 YGPFEEQLVRFVSRQVLYGLSYLHSKGIIHRDLKADNLLIDFDGVCKISDFGISKHSDNV 983
Query: 1195 YSN-SDMTMRGTVFWMAPEMVDTAH-GYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAM 1252
Y N ++++M+G++FWMAPE++ H GYSAKVD+WSLGCVVLEM AG+RPWS E + AM
Sbjct: 984 YDNDANLSMQGSIFWMAPEVIHNDHQGYSAKVDVWSLGCVVLEMLAGRRPWSTDEAIQAM 1043
Query: 1253 FQIGKSKTAPPIPDDTKDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPFCKTSSSFDFP 1312
F++G K APPIP + VSP FL+ CF ++ ++RPTA+ L+ HPF K F+F
Sbjct: 1044 FKLGTEKKAPPIPSELVSQVSPEAIQFLNACFTVNADVRPTAEELLNHPFMKCDEEFNFK 1103
Query: 1313 KTKL 1316
T L
Sbjct: 1104 DTNL 1107
>SPBC1D7.05c [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 362
Score = 237 bits (605), Expect = 8e-62
Identities = 124/272 (45%), Positives = 179/272 (65%), Gaps = 15/272 (5%)
Query: 1038 WIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKD 1097
WI+G +IG GSFG VYL +N ++GE++AVKQV + S + +++AL E++ L++
Sbjct: 97 WIRGALIGSGSFGQVYLGMNASSGELMAVKQVILDSVSESKDRHAKLLDALAGEIALLQE 156
Query: 1098 LNHVNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYL 1157
L+H +IVQYLG + ++FLEYV GGSV L+ MYG F++ L+++ KQ L+GL YL
Sbjct: 157 LSHEHIVQYLGSNLNSDHLNIFLEYVPGGSVAGLLTMYGSFEETLVKNFIKQTLKGLEYL 216
Query: 1158 HSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMT------MRGTVFWMAP 1211
HS+GI+HRD+K N+L+DN G KISDFGIS+K + S S T +G+ FWMAP
Sbjct: 217 HSRGIVHRDIKGANILVDNKGKIKISDFGISKKL-ELNSTSTKTGGARPSFQGSSFWMAP 275
Query: 1212 EMV-DTAHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKD 1270
E+V T H + K DIWSLGC+V+EM K P+ N + + A+F+IG++ P P +
Sbjct: 276 EVVKQTMH--TEKTDIWSLGCLVIEMLTSKHPYPNCDQMQAIFRIGEN-ILPEFPSN--- 329
Query: 1271 LVSPAGQSFLDQCFEIDPEMRPTADSLVGHPF 1302
+S + FL++ F ID +RPTA L+ HPF
Sbjct: 330 -ISSSAIDFLEKTFAIDCNLRPTASELLSHPF 360
>At3g06030 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 651
Score = 237 bits (604), Expect = 1e-61
Identities = 120/284 (42%), Positives = 180/284 (63%), Gaps = 9/284 (3%)
Query: 1032 EYKEFAWIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSE 1091
E W KGE+IG G+FG VY+ +N+ +GE+LA+KQV + S+ E + L+ E
Sbjct: 62 EAPSIRWRKGELIGCGAFGRVYMGMNLDSGELLAIKQVLIAPSSASKEKTQGHIRELEEE 121
Query: 1092 VSTLKDLNHVNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVL 1151
V LK+L+H NIV+YLG ++ ++ +E+V GGS+ SL+ +G F + +I TKQ+L
Sbjct: 122 VQLLKNLSHPNIVRYLGTVRESDSLNILMEFVPGGSISSLLEKFGSFPEPVIIMYTKQLL 181
Query: 1152 EGLAYLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYS-NSDMTMRGTVFWMA 1210
GL YLH+ GI+HRD+K N+L+DN G +++DFG S+K + + N +M+GT +WMA
Sbjct: 182 LGLEYLHNNGIMHRDIKGANILVDNKGCIRLADFGASKKVVELATVNGAKSMKGTPYWMA 241
Query: 1211 PEMV-DTAHGYSAKVDIWSLGCVVLEMFAGKRPWS-NFEVVAAMFQIGKSKTAPPIPDDT 1268
PE++ T H +SA DIWS+GC V+EM GK PWS ++ AA+ IG++K PPIP+D
Sbjct: 242 PEVILQTGHSFSA--DIWSVGCTVIEMATGKPPWSEQYQQFAAVLHIGRTKAHPPIPED- 298
Query: 1269 KDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPFCKTSSSFDFP 1312
+SP + FL +C +P +R +A L+ HPF +P
Sbjct: 299 ---LSPEAKDFLMKCLHKEPSLRLSATELLQHPFVTGKRQEPYP 339
>At1g09000 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 666
Score = 237 bits (604), Expect = 1e-61
Identities = 122/281 (43%), Positives = 185/281 (65%), Gaps = 13/281 (4%)
Query: 1037 AWIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLK 1096
+W KG++IG+G+FG VY+ +N+ +GE+LAVKQV + + E + ++ L+ EV LK
Sbjct: 68 SWRKGQLIGRGAFGTVYMGMNLDSGELLAVKQVLIAANFASKEKTQAHIQELEEEVKLLK 127
Query: 1097 DLNHVNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAY 1156
+L+H NIV+YLG ++ ++ LE+V GGS+ SL+ +G F + ++R T+Q+L GL Y
Sbjct: 128 NLSHPNIVRYLGTVREDDTLNILLEFVPGGSISSLLEKFGPFPESVVRTYTRQLLLGLEY 187
Query: 1157 LHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYS-NSDMTMRGTVFWMAPEMV- 1214
LH+ I+HRD+K N+L+DN G K++DFG S++ + + +M+GT +WMAPE++
Sbjct: 188 LHNHAIMHRDIKGANILVDNKGCIKLADFGASKQVAELATMTGAKSMKGTPYWMAPEVIL 247
Query: 1215 DTAHGYSAKVDIWSLGCVVLEMFAGKRPWS-NFEVVAAMFQIGKSKTAPPIPDDTKDLVS 1273
T H +SA DIWS+GC V+EM GK PWS ++ VAA+F IG +K+ PPIP D +S
Sbjct: 248 QTGHSFSA--DIWSVGCTVIEMVTGKAPWSQQYKEVAAIFFIGTTKSHPPIP----DTLS 301
Query: 1274 PAGQSFLDQCFEIDPEMRPTADSLVGHPFC----KTSSSFD 1310
+ FL +C + P +RPTA L+ HPF K S+S D
Sbjct: 302 SDAKDFLLKCLQEVPNLRPTASELLKHPFVMGKHKESASTD 342
>At1g54960 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 585
Score = 234 bits (598), Expect = 5e-61
Identities = 124/298 (41%), Positives = 188/298 (62%), Gaps = 20/298 (6%)
Query: 1015 ITDKRTISINKS----------RNSRGEYKE-FAWIKGEIIGKGSFGAVYLALNVTTGEM 1063
+ DK T I KS NS + K W KG++IG+G+FG VY+ +N+ +GE+
Sbjct: 34 LADKITSCIRKSMVFAKSQSPPNNSTVQIKPPIRWRKGQLIGRGAFGTVYMGMNLDSGEL 93
Query: 1064 LAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHVNIVQYLGFEEKNGIYSLFLEYV 1123
LAVKQV + + E + ++ L+ EV LK+L+H NIV+YLG ++ ++ LE+V
Sbjct: 94 LAVKQVLITSNCASKEKTQAHIQELEEEVKLLKNLSHPNIVRYLGTVREDETLNILLEFV 153
Query: 1124 AGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHSKGILHRDMKADNLLLDNDGVCKIS 1183
GGS+ SL+ +G F + ++R T Q+L GL YLH+ I+HRD+K N+L+DN G K++
Sbjct: 154 PGGSISSLLEKFGAFPESVVRTYTNQLLLGLEYLHNHAIMHRDIKGANILVDNQGCIKLA 213
Query: 1184 DFGISRKSNNIYSNSD-MTMRGTVFWMAPEMV-DTAHGYSAKVDIWSLGCVVLEMFAGKR 1241
DFG S++ + + S +M+GT +WMAPE++ T H +SA DIWS+GC V+EM GK
Sbjct: 214 DFGASKQVAELATISGAKSMKGTPYWMAPEVILQTGHSFSA--DIWSVGCTVIEMVTGKA 271
Query: 1242 PWS-NFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQSFLDQCFEIDPEMRPTADSLV 1298
PWS ++ +AA+F IG +K+ PPIPD+ +S FL +C + +P +RPTA L+
Sbjct: 272 PWSQQYKEIAAIFHIGTTKSHPPIPDN----ISSDANDFLLKCLQQEPNLRPTASELL 325
>At1g53570 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 608
Score = 234 bits (596), Expect = 9e-61
Identities = 120/282 (42%), Positives = 179/282 (62%), Gaps = 16/282 (5%)
Query: 1038 WIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKD 1097
W KG+ +G G+FG VYL N G+M A+K+V V S D+++ ++ L E++ L
Sbjct: 214 WKKGKFLGSGTFGQVYLGFNSEKGKMCAIKEVKV---ISDDQTSKECLKQLNQEINLLNQ 270
Query: 1098 LNHVNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYL 1157
L H NIVQY G E S++LEYV+GGS+ L++ YG F + +I++ T+Q+L GLAYL
Sbjct: 271 LCHPNIVQYYGSELSEETLSVYLEYVSGGSIHKLLKDYGSFTEPVIQNYTRQILAGLAYL 330
Query: 1158 HSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVDTA 1217
H + +HRD+K N+L+D +G K++DFG+++ ++ ++ +G+ +WMAPE+V +
Sbjct: 331 HGRNTVHRDIKGANILVDPNGEIKLADFGMAKHVTAF--STMLSFKGSPYWMAPEVVMSQ 388
Query: 1218 HGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQ 1277
+GY+ VDIWSLGC +LEM K PWS FE VAA+F+IG SK P IPD +S +
Sbjct: 389 NGYTHAVDIWSLGCTILEMATSKPPWSQFEGVAAIFKIGNSKDTPEIPDH----LSNDAK 444
Query: 1278 SFLDQCFEIDPEMRPTADSLVGHPFCK-------TSSSFDFP 1312
+F+ C + +P +RPTA L+ HPF + TS DFP
Sbjct: 445 NFIRLCLQRNPTVRPTASQLLEHPFLRNTTRVASTSLPKDFP 486
>At1g63700 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 883
Score = 231 bits (590), Expect = 4e-60
Identities = 118/275 (42%), Positives = 172/275 (61%), Gaps = 9/275 (3%)
Query: 1038 WIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKD 1097
W KG ++G GSFG VYL N +GEM A+K+VT+ S D + + L E+S L
Sbjct: 400 WKKGRLLGMGSFGHVYLGFNSESGEMCAMKEVTL---CSDDPKSRESAQQLGQEISVLSR 456
Query: 1098 LNHVNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYL 1157
L H NIVQY G E + ++LEYV+GGS+ L++ YG+F + IR+ T+Q+L GLAYL
Sbjct: 457 LRHQNIVQYYGSETVDDKLYIYLEYVSGGSIYKLLQEYGQFGENAIRNYTQQILSGLAYL 516
Query: 1158 HSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVDTA 1217
H+K +HRD+K N+L+D G K++DFG+++ + + ++ +G+ +WMAPE++ +
Sbjct: 517 HAKNTVHRDIKGANILVDPHGRVKVADFGMAK--HITAQSGPLSFKGSPYWMAPEVIKNS 574
Query: 1218 HGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQ 1277
+G + VDIWSLGC VLEM K PWS +E V AMF+IG SK P IPD +S G+
Sbjct: 575 NGSNLAVDIWSLGCTVLEMATTKPPWSQYEGVPAMFKIGNSKELPDIPDH----LSEEGK 630
Query: 1278 SFLDQCFEIDPEMRPTADSLVGHPFCKTSSSFDFP 1312
F+ +C + +P RPTA L+ H F + + P
Sbjct: 631 DFVRKCLQRNPANRPTAAQLLDHAFVRNVMPMERP 665
>YLR362w [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 717
Score = 229 bits (585), Expect = 2e-59
Identities = 129/303 (42%), Positives = 186/303 (60%), Gaps = 44/303 (14%)
Query: 1038 WIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVP-----------------EFSSQDES 1080
W+KG IG GSFG+VYL +N TGE++AVKQV + E + Q+E
Sbjct: 415 WLKGACIGSGSFGSVYLGMNAHTGELMAVKQVEIKNNNIGVPTDNNKQANSDENNEQEEQ 474
Query: 1081 --------AIS-----------MVEALKSEVSTLKDLNHVNIVQYLGFEEKNGIYSLFLE 1121
A+S MV+AL+ E++ LK+L+H NIV Y G ++ G ++FLE
Sbjct: 475 QEKIEDVGAVSHPKTNQNIHRKMVDALQHEMNLLKELHHENIVTYYGASQEGGNLNIFLE 534
Query: 1122 YVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHSKGILHRDMKADNLLLDNDGVCK 1181
YV GGSV S++ YG F++ LI + T+Q+L G+AYLH K I+HRD+K N+L+D G K
Sbjct: 535 YVPGGSVSSMLNNYGPFEESLITNFTRQILIGVAYLHKKNIIHRDIKGANILIDIKGCVK 594
Query: 1182 ISDFGISRKSN--NIYSNSDMTMRGTVFWMAPEMVDTAHGYSAKVDIWSLGCVVLEMFAG 1239
I+DFGIS+K + N N +++G+VFWM+PE+V +AK DIWS GCVV+EMF G
Sbjct: 595 ITDFGISKKLSPLNKKQNKRASLQGSVFWMSPEVVKQT-ATTAKADIWSTGCVVIEMFTG 653
Query: 1240 KRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQSFLDQCFEIDPEMRPTADSLVG 1299
K P+ +F + A+F+IG + T P IP + G++FL + FE+D + RP+A L+
Sbjct: 654 KHPFPDFSQMQAIFKIG-TNTTPEIP----SWATSEGKNFLRKAFELDYQYRPSALELLQ 708
Query: 1300 HPF 1302
HP+
Sbjct: 709 HPW 711
>At5g66850 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 376
Score = 221 bits (564), Expect = 5e-57
Identities = 115/277 (41%), Positives = 173/277 (61%), Gaps = 19/277 (6%)
Query: 1038 WIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKD 1097
W KG++IG+G+FG+VY+A N TG + A+K+V E D + ++ L+ E+ L +
Sbjct: 5 WKKGKLIGRGTFGSVYVASNSETGALCAMKEV---ELFPDDPKSAECIKQLEQEIKLLSN 61
Query: 1098 LNHVNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMY-GRFDDQLIRHLTKQVLEGLAY 1156
L H NIVQY G E + ++LEYV GS+ IR + G + ++R+ T+ +L GLAY
Sbjct: 62 LQHPNIVQYFGSETVEDRFFIYLEYVHPGSINKYIRDHCGTMTESVVRNFTRHILSGLAY 121
Query: 1157 LHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMV-- 1214
LH+K +HRD+K NLL+D GV K++DFG+++ +D++++G+ +WMAPE++
Sbjct: 122 LHNKKTVHRDIKGANLLVDASGVVKLADFGMAKHLTG--QRADLSLKGSPYWMAPEVLMQ 179
Query: 1215 -----DTAHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTK 1269
D+ + VDIWSLGC ++EMF GK PWS FE AAMF++ + +PPIP+
Sbjct: 180 AVMQKDSNPDLAFAVDIWSLGCTIIEMFTGKPPWSEFEGAAAMFKV--MRDSPPIPES-- 235
Query: 1270 DLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPFCKTS 1306
+SP G+ FL CF+ +P RPTA L+ H F K S
Sbjct: 236 --MSPEGKDFLRLCFQRNPAERPTASMLLEHRFLKNS 270
>At4g08500 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 608
Score = 204 bits (518), Expect = 1e-51
Identities = 126/368 (34%), Positives = 201/368 (54%), Gaps = 38/368 (10%)
Query: 956 LSSRGESSQFLTPVKSLKPPKRTKTIRIIAQEASEARKNEVSQKLQRKNTKMWGTKVVEI 1015
+ RG S FLT + KR + + +SE +E K + + G + +++
Sbjct: 240 IDHRGSSWDFLTHFAPSETVKRPSS----SSSSSEDGCDEEEGKEEEAEAEEMGARFIQL 295
Query: 1016 TD---------------KRTISINKSRNSRGEYKEFAWIKGEIIGKGSFGAVYLALNVTT 1060
D T+S G +W KG+++G+GSFG+VY ++
Sbjct: 296 GDTADETCSFTTNEGDSSSTVSNTSPIYPDGGAIITSWQKGQLLGRGSFGSVYEGIS-GD 354
Query: 1061 GEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHVNIVQYLGFEEKNGIYSLFL 1120
G+ AVK+V++ + SQ + I +E E+ L L H NIV+Y G + +FL
Sbjct: 355 GDFFAVKEVSLLDQGSQAQECIQQLEG---EIKLLSQLQHQNIVRYRGTAKDGSNLYIFL 411
Query: 1121 EYVAGGSVGSLIRMYGRFD--DQLIRHLTKQVLEGLAYLHSKGILHRDMKADNLLLDNDG 1178
E V + GSL+++Y R+ D ++ T+Q+L+GL YLH KG +HRD+K N+L+D +G
Sbjct: 412 ELV---TQGSLLKLYQRYQLRDSVVSLYTRQILDGLKYLHDKGFIHRDIKCANILVDANG 468
Query: 1179 VCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVD--TAHGYSAKVDIWSLGCVVLEM 1236
K++DFG+++ S N + +GT FWMAPE+++ + GY + DIWSLGC VLEM
Sbjct: 469 AVKLADFGLAKVSK---FNDIKSCKGTPFWMAPEVINRKDSDGYGSPADIWSLGCTVLEM 525
Query: 1237 FAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQSFLDQCFEIDPEMRPTADS 1296
G+ P+S+ E V A+F+IG+ T P +P D +S + F+ +C +++PE RPTA
Sbjct: 526 CTGQIPYSDLEPVQALFRIGRG-TLPEVP----DTLSLDARLFILKCLKVNPEERPTAAE 580
Query: 1297 LVGHPFCK 1304
L+ HPF +
Sbjct: 581 LLNHPFVR 588
>Hs4505153 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 626
Score = 201 bits (512), Expect = 5e-51
Identities = 107/271 (39%), Positives = 163/271 (59%), Gaps = 13/271 (4%)
Query: 1038 WIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKD 1097
W +G+++G+G+FG VYL +V TG LA KQV +F V AL+ E+ LK+
Sbjct: 362 WRRGKLLGQGAFGRVYLCYDVDTGRELASKQV---QFDPDSPETSKEVSALECEIQLLKN 418
Query: 1098 LNHVNIVQYLGF--EEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLA 1155
L H IVQY G + ++F+EY+ GGSV ++ YG + + R T+Q+LEG++
Sbjct: 419 LQHERIVQYYGCLRDRAEKTLTIFMEYMPGGSVKDQLKAYGALTESVTRKYTRQILEGMS 478
Query: 1156 YLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNI-YSNSDM-TMRGTVFWMAPEM 1213
YLHS I+HRD+K N+L D+ G K+ DFG S++ I S + M ++ GT +WM+PE+
Sbjct: 479 YLHSNMIVHRDIKGANILRDSAGNVKLGDFGASKRLQTICMSGTGMRSVTGTPYWMSPEV 538
Query: 1214 VDTAHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVS 1273
+ + GY K D+WSLGC V+EM K PW+ +E +AA+F+I T P +P +S
Sbjct: 539 I-SGEGYGRKADVWSLGCTVVEMLTEKPPWAEYEAMAAIFKIATQPTNPQLPSH----IS 593
Query: 1274 PAGQSFLDQCFEIDPEMRPTADSLVGHPFCK 1304
G+ FL + F ++ RP+A+ L+ H F +
Sbjct: 594 EHGRDFLRRIF-VEARQRPSAEELLTHHFAQ 623
>SPBC21.06c [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 1062
Score = 200 bits (509), Expect = 1e-50
Identities = 110/294 (37%), Positives = 176/294 (59%), Gaps = 21/294 (7%)
Query: 1041 GEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNH 1100
G+ +GKG+FGAVY LN+ GE +AVK+V + + D S I M E+ LK+L+H
Sbjct: 12 GDCLGKGAFGAVYRGLNIKNGETVAVKKVKLSKMLKSDLSVIKM------EIDLLKNLDH 65
Query: 1101 VNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHSK 1160
NIV+Y G + N + LEY GS+ S+ + +G+ + L+ T QVL+GL YLH++
Sbjct: 66 PNIVKYRGSYQTNDSLCIILEYCENGSLRSICKNFGKIPENLVALYTFQVLQGLLYLHNQ 125
Query: 1161 GILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVDTAHGY 1220
G++HRD+K N+L DG K++DFG++ K N + D ++ G+ +WMAPE+++ G
Sbjct: 126 GVIHRDIKGANILTTKDGTIKLADFGVATKINAL---EDHSVVGSPYWMAPEVIELV-GA 181
Query: 1221 SAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQSFL 1280
+ DIWS+GC V+E+ G P+ + + +A+F++ K + PP+P + +S A +SFL
Sbjct: 182 TTASDIWSVGCTVIELLDGNPPYYDLDPTSALFRMVKDE-HPPLPSN----ISSAAKSFL 236
Query: 1281 DQCFEIDPEMRPTADSLVGHPFC---KTSSSFDFPKTKLAQFIKSNDKLNSSRL 1331
QCF+ DP +R L+ HP+ +TSS F + + K N+++ S L
Sbjct: 237 MQCFQKDPNLRIKTRKLLKHPWVIMNQTSSKF---SDAIDEVQKYNERVKESTL 287
>HsM5729922 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 618
Score = 197 bits (502), Expect = 7e-50
Identities = 113/291 (38%), Positives = 168/291 (56%), Gaps = 14/291 (4%)
Query: 1017 DKRTISI-NKSRNSRGEYKEFAWIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFS 1075
D T+++ + S SR W G+++G+G+FG VYL +V TG LAVKQV +F
Sbjct: 333 DNPTLTVMDISPPSRSPRAPTNWRLGKLLGQGAFGRVYLCYDVDTGRELAVKQV---QFD 389
Query: 1076 SQDESAISMVEALKSEVSTLKDLNHVNIVQYLGF--EEKNGIYSLFLEYVAGGSVGSLIR 1133
V AL+ E+ LK+ H IVQY G + + S+F+EY+ GGS+ ++
Sbjct: 390 PDSPETSKEVNALECEIQLLKNFLHERIVQYYGCLRDPQEKTLSIFMEYMPGGSIKDQLK 449
Query: 1134 MYGRFDDQLIRHLTKQVLEGLAYLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNN 1193
YG + R T+Q+LEG+ YLHS ILHRD+K N+L D+ G K+ DFG S++
Sbjct: 450 AYGALTENGTRKYTRQILEGVHYLHSNMILHRDIKGANILRDSTGNVKLGDFGASKRLQT 509
Query: 1194 I-YSNSDM-TMRGTVFWMAPEMVDTAHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAA 1251
I S + M ++ GT +WM+PE++ + GY K DIWS+ C V+EM K PW+ FE +AA
Sbjct: 510 ICLSGTGMKSVTGTPYWMSPEVI-SGQGYGRKADIWSVACTVVEMLTEKPPWAEFEAMAA 568
Query: 1252 MFQIGKSKTAPPIPDDTKDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPF 1302
+F+I T P +P D + FL + F ++ ++RP+AD L+ H F
Sbjct: 569 IFKIATQPTNPKLPPHVSDYT----RDFLKRIF-VEAKLRPSADELLRHMF 614
>Hs21735556 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 620
Score = 196 bits (497), Expect = 3e-49
Identities = 112/291 (38%), Positives = 169/291 (57%), Gaps = 14/291 (4%)
Query: 1017 DKRTISI-NKSRNSRGEYKEFAWIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFS 1075
D T+++ + S SR W G+++G+G+FG VYL +V TG LAVKQV +F
Sbjct: 335 DNPTLTVMDISPPSRSPRAPTNWRLGKLLGQGAFGRVYLCYDVDTGRELAVKQV---QFD 391
Query: 1076 SQDESAISMVEALKSEVSTLKDLNHVNIVQYLGF--EEKNGIYSLFLEYVAGGSVGSLIR 1133
V AL+ E+ LK+L H IVQY G + + S+F+EY+ GGS+ ++
Sbjct: 392 PDSPETSKEVNALECEIQLLKNLLHERIVQYYGCLRDPQEKTLSIFMEYMPGGSIKDQLK 451
Query: 1134 MYGRFDDQLIRHLTKQVLEGLAYLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNN 1193
YG + + R T+Q+LEG+ YLHS I+ RD+K N+L D+ G K+ DFG S++
Sbjct: 452 AYGALTENVTRKYTRQILEGVHYLHSNMIVLRDIKGANILRDSTGNVKLGDFGASKRLQT 511
Query: 1194 I-YSNSDM-TMRGTVFWMAPEMVDTAHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAA 1251
I S + M ++ GT +WM+PE++ + GY K DIWS+ C V+EM K PW+ FE +AA
Sbjct: 512 ICLSGTGMKSVTGTPYWMSPEVI-SGEGYGRKADIWSVACTVVEMLTEKPPWAEFEAMAA 570
Query: 1252 MFQIGKSKTAPPIPDDTKDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPF 1302
+F+I T P +P D + FL + F ++ ++RP+AD L+ H F
Sbjct: 571 IFKIATQPTNPKLPPHVSDYT----RDFLKRIF-VEAKLRPSADELLRHMF 616
>At4g08480 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 773
Score = 195 bits (496), Expect = 4e-49
Identities = 110/272 (40%), Positives = 169/272 (61%), Gaps = 19/272 (6%)
Query: 1037 AWIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLK 1096
+W KG+++ +GSFG+VY A++ G+ AVK+V++ + SQ + I +E E++ L
Sbjct: 500 SWQKGQLLRQGSFGSVYEAIS-EDGDFFAVKEVSLLDQGSQAQECIQQLEG---EIALLS 555
Query: 1097 DLNHVNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAY 1156
L H NI++Y G ++ +FLE V GS+ L R Y + D LI TKQ+L+GL Y
Sbjct: 556 QLEHQNILRYRGTDKDGSNLYIFLELVTQGSLLELYRRY-QIRDSLISLYTKQILDGLKY 614
Query: 1157 LHSKGILHRDMKADNLLLDNDGVCKISDFGISR--KSNNIYSNSDMTMRGTVFWMAPEMV 1214
LH KG +HRD+K +L+D +G K++DFG+++ K N+I S + T+FWMAPE++
Sbjct: 615 LHHKGFIHRDIKCATILVDANGTVKLADFGLAKVSKLNDIKSRKE-----TLFWMAPEVI 669
Query: 1215 DTA--HGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLV 1272
+ GY + DIWSLGC VLEM G+ P+S+ E V A+F+I + T P +P D +
Sbjct: 670 NRKDNDGYRSPADIWSLGCTVLEMCTGQIPYSDLEPVEALFRIRRG-TLPEVP----DTL 724
Query: 1273 SPAGQSFLDQCFEIDPEMRPTADSLVGHPFCK 1304
S + F+ +C +++PE RPTA L+ HPF +
Sbjct: 725 SLDARHFILKCLKLNPEERPTATELLNHPFVR 756
>YCR073c [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and related
serine/threonine protein kinases
Length = 1331
Score = 192 bits (489), Expect = 2e-48
Identities = 117/326 (35%), Positives = 186/326 (56%), Gaps = 33/326 (10%)
Query: 998 QKLQRKNTKMWGTKVVEITD---KRTISINKSRNSRGEYKEFAWIKGEIIGKGSFGAVYL 1054
+K ++N + G KV++ TD K +S+ S ++ W K IG G+FG VY
Sbjct: 996 EKTMKRNPRQMG-KVLDATDQGNKYLLSLASSLSN----VSMRWQKRSFIGGGTFGQVYS 1050
Query: 1055 ALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHVNIVQYLGFEEKNG 1114
A+N+ GE+LAVK++ + + ++ + + +K E++ L+ LNH NIVQY G E
Sbjct: 1051 AINLENGEILAVKEIKIHDTTTMKK----IFPLIKEEMTVLEMLNHPNIVQYYGVEVHRD 1106
Query: 1115 IYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHL-TKQVLEGLAYLHSKGILHRDMKADNLL 1173
++F+EY GGS+ SL+ +GR +D+++ + T ++LEGLAYLH G++HRD+K +N+L
Sbjct: 1107 KVNIFMEYCEGGSLASLLD-HGRIEDEMVTQVYTFELLEGLAYLHQSGVVHRDIKPENIL 1165
Query: 1174 LDNDGVCKISDFGISR---------------KSNNIYSNSDMTMRGTVFWMAPEMV--DT 1216
LD +G+ K DFG +R + + + S M GT +MAPE +
Sbjct: 1166 LDFNGIIKYVDFGTARTVVGSRTRTVRNAAVQDFGVETKSLNEMMGTPMYMAPETISGSA 1225
Query: 1217 AHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAG 1276
G D+W+LGCVVLEM G+RPWSN + A+ + P +P+ +D ++ AG
Sbjct: 1226 VKGKLGADDVWALGCVVLEMATGRRPWSNLDNEWAIMYHVAAGRIPQLPN--RDEMTAAG 1283
Query: 1277 QSFLDQCFEIDPEMRPTADSLVGHPF 1302
++FL++C DP MR TA L+ P+
Sbjct: 1284 RAFLERCLVQDPTMRATAVELLIDPW 1309
>At3g13530 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 1368
Score = 192 bits (488), Expect = 3e-48
Identities = 102/271 (37%), Positives = 163/271 (59%), Gaps = 15/271 (5%)
Query: 1038 WIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKD 1097
++ G+ IGKG++G VY L++ G+ +A+KQV++ +D + + E+ LK+
Sbjct: 20 YMLGDEIGKGAYGRVYKGLDLENGDFVAIKQVSLENIVQED------LNTIMQEIDLLKN 73
Query: 1098 LNHVNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIR--MYGRFDDQLIRHLTKQVLEGLA 1155
LNH NIV+YLG + + LEYV GS+ ++I+ +G F + L+ QVLEGL
Sbjct: 74 LNHKNIVKYLGSSKTKTHLHIILEYVENGSLANIIKPNKFGPFPESLVAVYIAQVLEGLV 133
Query: 1156 YLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVD 1215
YLH +G++HRD+K N+L +G+ K++DFG++ K N N+ + GT +WMAPE+++
Sbjct: 134 YLHEQGVIHRDIKGANILTTKEGLVKLADFGVATKLNEADVNTHSVV-GTPYWMAPEVIE 192
Query: 1216 TAHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPA 1275
+ G A DIWS+GC V+E+ P+ + + + A+F+I + PPIPD +SP
Sbjct: 193 MS-GVCAASDIWSVGCTVIELLTCVPPYYDLQPMPALFRIVQDDN-PPIPDS----LSPD 246
Query: 1276 GQSFLDQCFEIDPEMRPTADSLVGHPFCKTS 1306
FL QCF+ D RP A +L+ HP+ + S
Sbjct: 247 ITDFLRQCFKKDSRQRPDAKTLLSHPWIRNS 277
>At4g08470 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 560
Score = 191 bits (486), Expect = 5e-48
Identities = 110/291 (37%), Positives = 172/291 (58%), Gaps = 16/291 (5%)
Query: 1015 ITDKRTISINKS-RNSRGEYKEFAWIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPE 1073
+ +KR + NK N R +W+KG+++G+GS+ +VY A++ G+ AVK+V++ +
Sbjct: 279 VKEKRKLMRNKLIENFRKPEDITSWLKGQLLGRGSYASVYEAIS-EDGDFFAVKEVSLLD 337
Query: 1074 FSSQDESAISMVEALKSEVSTLKDLNHVNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIR 1133
Q + I +E E++ L L H NIV+Y G + +FLE V GSV L
Sbjct: 338 KGIQAQECIQQLEG---EIALLSQLQHQNIVRYRGTAKDVSKLYIFLELVTQGSVQKLYE 394
Query: 1134 MYGRFDDQLIRHLTKQVLEGLAYLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNN 1193
Y + ++ T+Q+L GL YLH KG +HRD+K N+L+D +G K++DFG++ S
Sbjct: 395 RY-QLSYTVVSLYTRQILAGLNYLHDKGFVHRDIKCANMLVDANGTVKLADFGLAEASK- 452
Query: 1194 IYSNSDMTMRGTVFWMAPEMVD--TAHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAA 1251
N M+ +GT+FWMAPE+++ + G + DIWSLGC VLEM G+ P+S+ + + A
Sbjct: 453 --FNDIMSCKGTLFWMAPEVINRKDSDGNGSPADIWSLGCTVLEMCTGQIPYSDLKPIQA 510
Query: 1252 MFQIGKSKTAPPIPDDTKDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPF 1302
F+IG+ T P +P D +S + F+ C +++PE RPTA L+ HPF
Sbjct: 511 AFKIGRG-TLPDVP----DTLSLDARHFILTCLKVNPEERPTAAELLHHPF 556
>At3g07980 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 1367
Score = 191 bits (485), Expect = 7e-48
Identities = 100/271 (36%), Positives = 164/271 (59%), Gaps = 15/271 (5%)
Query: 1038 WIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKD 1097
++ G+ IGKG++G VY+ L++ G+ +A+KQV++ +D + + E+ LK+
Sbjct: 20 YMLGDEIGKGAYGRVYIGLDLENGDFVAIKQVSLENIGQED------LNTIMQEIDLLKN 73
Query: 1098 LNHVNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIR--MYGRFDDQLIRHLTKQVLEGLA 1155
LNH NIV+YLG + + LEYV GS+ ++I+ +G F + L+ QVLEGL
Sbjct: 74 LNHKNIVKYLGSLKTKTHLHIILEYVENGSLANIIKPNKFGPFPESLVTVYIAQVLEGLV 133
Query: 1156 YLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVD 1215
YLH +G++HRD+K N+L +G+ K++DFG++ K N N+ + GT +WMAPE+++
Sbjct: 134 YLHEQGVIHRDIKGANILTTKEGLVKLADFGVATKLNEADFNTHSVV-GTPYWMAPEVIE 192
Query: 1216 TAHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPA 1275
+ G A DIWS+GC ++E+ P+ + + + A+++I + T PPIPD +SP
Sbjct: 193 LS-GVCAASDIWSVGCTIIELLTCVPPYYDLQPMPALYRIVQDDT-PPIPDS----LSPD 246
Query: 1276 GQSFLDQCFEIDPEMRPTADSLVGHPFCKTS 1306
FL CF+ D RP A +L+ HP+ + S
Sbjct: 247 ITDFLRLCFKKDSRQRPDAKTLLSHPWIRNS 277
>YNR031c [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and related
serine/threonine protein kinases
Length = 1579
Score = 190 bits (482), Expect = 1e-47
Identities = 128/357 (35%), Positives = 189/357 (52%), Gaps = 47/357 (13%)
Query: 983 IIAQEASEARKNEVSQKLQR--KNTKMWGTKVVEITDKRTISINKSRNSRGEYKEFAWIK 1040
++ Q SE R + + +R +N G KV++ +DK + +S W K
Sbjct: 1211 MMLQVNSEFRVQSIMELEERIKRNPHQTG-KVIDDSDKGNKYLVSLASSISNVS-MRWQK 1268
Query: 1041 GEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNH 1100
IG G+FG VY A+++ GE+LAVK++ + + S + + +K E+S L+ LNH
Sbjct: 1269 RNFIGGGTFGRVYSAVDLDNGEILAVKEINIQDSKSMQK----IFPLIKEEMSVLEILNH 1324
Query: 1101 VNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHL-TKQVLEGLAYLHS 1159
NIV Y G E ++F+EY GGS+ +L+ +GR +D+++ + T Q+LEGLAYLH
Sbjct: 1325 PNIVSYYGVEVHRDKVNIFMEYCEGGSLAALLE-HGRIEDEMVTQVYTLQLLEGLAYLHE 1383
Query: 1160 KGILHRDMKADNLLLDNDGVCKISDFGISRK---------SNNIYSNSD----------- 1199
GI+HRD+K +N+LLD +GV K DFG ++K S N N+D
Sbjct: 1384 SGIVHRDVKPENILLDFNGVIKYVDFGAAKKIANNGTRLASMNKIENADGEHEDVTHVSD 1443
Query: 1200 -----------MTMRGTVFWMAPEMV--DTAHGYSAKVDIWSLGCVVLEMFAGKRPWSNF 1246
+ M GT +MAPE + T G D+WSLGCVVLEM G+RPW+N
Sbjct: 1444 SKAVKNNENALLDMMGTPMYMAPESITGSTTKGKLGADDVWSLGCVVLEMITGRRPWANL 1503
Query: 1247 E-VVAAMFQIGKSKTAPPIPDDTKDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPF 1302
+ A M+ + T P P TKD VS AG FL++C +P R +A L+ P+
Sbjct: 1504 DNEWAIMYHVAAGHT-PQFP--TKDEVSSAGMKFLERCLIQNPSKRASAVELLMDPW 1557
>Hs5174547 [T] KOG4279 Serine/threonine protein kinase
Length = 1374
Score = 186 bits (472), Expect = 2e-46
Identities = 119/298 (39%), Positives = 172/298 (56%), Gaps = 20/298 (6%)
Query: 1043 IIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHVN 1102
++GKG++G VY +++ +A+K++ PE S+ + L E++ K L H N
Sbjct: 685 VLGKGTYGIVYAGRDLSNQVRIAIKEI--PERDSRYS------QPLHEEIALHKHLKHKN 736
Query: 1103 IVQYLGFEEKNGIYSLFLEYVAGGSVGSLIR-MYGRFDD--QLIRHLTKQVLEGLAYLHS 1159
IVQYLG +NG +F+E V GGS+ +L+R +G D Q I TKQ+LEGL YLH
Sbjct: 737 IVQYLGSFSENGFIKIFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHD 796
Query: 1160 KGILHRDMKADNLLLDN-DGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVDTA- 1217
I+HRD+K DN+L++ GV KISDFG S++ I ++ T GT+ +MAPE++D
Sbjct: 797 NQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLAGINPCTE-TFTGTLQYMAPEIIDKGP 855
Query: 1218 HGYSAKVDIWSLGCVVLEMFAGKRPWSNF-EVVAAMFQIGKSKTAPPIPDDTKDLVSPAG 1276
GY DIWSLGC ++EM GK P+ E AAMF++G K P IP+ +S
Sbjct: 856 RGYGKAADIWSLGCTIIEMATGKPPFYELGEPQAAMFKVGMFKVHPEIPES----MSAEA 911
Query: 1277 QSFLDQCFEIDPEMRPTADSLVGHPFCKTSSSFDFPKTKL-AQFIKSNDKLNSSRLRI 1333
++F+ +CFE DP+ R A+ L+ F K SS + KL A SN+ L S L +
Sbjct: 912 KAFILKCFEPDPDKRACANDLLVDEFLKVSSKKKKTQPKLSALSAGSNEYLRSISLPV 969
>At4g12020_6 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 422
Score = 184 bits (466), Expect = 1e-45
Identities = 128/376 (34%), Positives = 196/376 (52%), Gaps = 62/376 (16%)
Query: 952 QPAFLSS---RGESSQFLT---PVKSLKPPKRTKTIRIIAQEASEARKNEVSQKLQRKNT 1005
QPA S RG + F+T P +++ PP +SEAR+ EV T
Sbjct: 65 QPAMKLSHIPRGSTWDFVTHFAPPETVAPPS----------SSSEAREEEVE-------T 107
Query: 1006 KMWGTKVVEITDKRTIS--INKSRNSR------------GEYKEFAWIKGEIIGKGSFGA 1051
+ G + + DK T S +NK +SR G + W KG+++G+GS G+
Sbjct: 108 EETGAMFIPLGDKETCSFTVNKGDSSRTISNTSPIYASEGSFIT-CWQKGQLLGRGSLGS 166
Query: 1052 VYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHVNIVQYLGFEE 1111
VY ++ G+ A K+V++ + SQ I VE ++ L L H NIV+Y G +
Sbjct: 167 VYEGISAD-GDFFAFKEVSLLDQGSQAHEWIQQVEG---GIALLSQLQHQNIVRYRGTTK 222
Query: 1112 KNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHSKGILHRDMKADN 1171
+FLE V GS+ L + + D ++ T+Q+L+GL YLH KG +HR++K N
Sbjct: 223 DESNLYIFLELVTQGSLRKLYQR-NQLGDSVVSLYTRQILDGLKYLHDKGFIHRNIKCAN 281
Query: 1172 LLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVF--WMAPEMV---DTAHGYSAKVDI 1226
+L+D +G K++DFG+++ M++ T + WMAPE++ GY DI
Sbjct: 282 VLVDANGTVKLADFGLAKV---------MSLWRTPYWNWMAPEVILNPKDYDGYGTPADI 332
Query: 1227 WSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQSFLDQCFEI 1286
WSLGC VLEM G+ P+S+ E+ A++ IG K P IP D++S + F+ C ++
Sbjct: 333 WSLGCTVLEMLTGQIPYSDLEIGTALYNIGTGK-LPKIP----DILSLDARDFILTCLKV 387
Query: 1287 DPEMRPTADSLVGHPF 1302
+PE RPTA L+ HPF
Sbjct: 388 NPEERPTAAELLNHPF 403
>SPAC9G1.02 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and related
serine/threonine protein kinases
Length = 1401
Score = 183 bits (465), Expect = 1e-45
Identities = 105/276 (38%), Positives = 161/276 (58%), Gaps = 18/276 (6%)
Query: 1038 WIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKD 1097
W +G + G FG VY +N+ TG++LAVK++ + + + S V+ + +E++ L+
Sbjct: 1037 WQQGHFVRSGMFGDVYTGVNMETGDLLAVKEIKLQD----SRTFRSTVDQIHNEMTVLER 1092
Query: 1098 LNHVNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQ-LIRHLTKQVLEGLAY 1156
LNH N+V Y G E +F+E+ GGS+ L+ +GR +D+ +++ Q+LEGLAY
Sbjct: 1093 LNHPNVVTYYGVEVHREKVYIFMEFCQGGSLADLLA-HGRIEDENVLKVYVVQLLEGLAY 1151
Query: 1157 LHSKGILHRDMKADNLLLDNDGVCKISDFG----ISRKSNNIYSNSDMT-----MRGTVF 1207
+HS+ ILHRD+K N+LLD+ G+ K SDFG +S ++ D+ + GT
Sbjct: 1152 IHSQHILHRDIKPANILLDHRGMIKYSDFGSALYVSPPTDPEVRYEDIQPELQHLAGTPM 1211
Query: 1208 WMAPEMV-DTAHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPD 1266
+MAPE++ T G +DIWSLGCV+LEM G PWS + A+ + P IP
Sbjct: 1212 YMAPEIILGTKKGDFGAMDIWSLGCVILEMMTGSTPWSEMDNEWAIMYHVAAMHTPSIPQ 1271
Query: 1267 DTKDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPF 1302
+ K +S + F++QCFE DPE RP A L+ HP+
Sbjct: 1272 NEK--ISSLARDFIEQCFERDPEQRPRAVDLLTHPW 1305
>Hs22050308_2 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 291
Score = 182 bits (461), Expect = 4e-45
Identities = 102/278 (36%), Positives = 162/278 (57%), Gaps = 16/278 (5%)
Query: 1038 WIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKD 1097
W+KG+ IG G+F + Y A +V TG ++AVKQVT +S ++ + VEAL+ E+ +
Sbjct: 20 WLKGQQIGLGAFSSCYQAQDVGTGTLMAVKQVTYVRNTSSEQEEV--VEALREEIRMMSH 77
Query: 1098 LNHVNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYL 1157
LNH NI++ LG + Y+LF+E++AGGSV L+ YG F + ++ + T+Q+L GL+YL
Sbjct: 78 LNHPNIIRMLGATCEKSNYNLFIEWMAGGSVAHLLSKYGAFKESVVINYTEQLLRGLSYL 137
Query: 1158 HSKGILHRDMKADNLLLDNDGV-CKISDFGISRKSNNIYSNS---DMTMRGTVFWMAPEM 1213
H I+HRD+K NLL+D+ G +I+DFG + + + + + + GT+ +MAPE+
Sbjct: 138 HENQIIHRDVKGANLLIDSTGQRLRIADFGAAARLASKGTGAGEFQGQLLGTIAFMAPEV 197
Query: 1214 VDTAHGYSAKVDIWSLGCVVLEMFAGKRPW-----SNFEVVAAMFQIGKSKTAPPIPDDT 1268
+ Y D+WS+GC ++EM K PW SN + I + TAP IP
Sbjct: 198 L-RGQQYGRSCDVWSVGCAIIEMACAKPPWNAEKHSNHLALIFKVIIASATTAPSIPSH- 255
Query: 1269 KDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPFCKTS 1306
+SP + +C E+ P+ RP + L+ HP +T+
Sbjct: 256 ---LSPGLRDVALRCLELQPQDRPPSRELLKHPVFRTT 290
>Hs4758702 [T] KOG4279 Serine/threonine protein kinase
Length = 1011
Score = 178 bits (452), Expect = 4e-44
Identities = 112/299 (37%), Positives = 169/299 (56%), Gaps = 24/299 (8%)
Query: 1015 ITDKRTISINKSRNSRGEYKEFAWIKGE-----IIGKGSFGAVYLALNVTTGEMLAVKQV 1069
+T+ + + + GE EF + E ++GKG++G VY + T +A+K++
Sbjct: 343 VTNPDSTAPAEEAEGAGEMLEFDYEYTETGERLVLGKGTYGVVYAGRDRHTRVRIAIKEI 402
Query: 1070 TVPEFSSQDESAISMVEALKSEVSTLKDLNHVNIVQYLGFEEKNGIYSLFLEYVAGGSVG 1129
PE S+ + L E++ + L H NIV+YLG + G +F+E V GGS+
Sbjct: 403 --PERDSR------FSQPLHEEIALHRRLRHKNIVRYLGSASQGGYLKIFMEEVPGGSLS 454
Query: 1130 SLIR-MYGRFDD--QLIRHLTKQVLEGLAYLHSKGILHRDMKADNLLLDN-DGVCKISDF 1185
SL+R ++G D I T+Q+L+GL YLH I+HRD+K DN+L++ G+ KISDF
Sbjct: 455 SLLRSVWGPLKDNESTISFYTRQILQGLGYLHDNHIVHRDIKGDNVLINTFSGLLKISDF 514
Query: 1186 GISRKSNNIYSNSDMTMRGTVFWMAPEMVDTA-HGYSAKVDIWSLGCVVLEMFAGKRPWS 1244
G S++ I ++ T GT+ +MAPE++D GY DIWSLGC V+EM G+ P+
Sbjct: 515 GTSKRLAGITPCTE-TFTGTLQYMAPEIIDQGPRGYGKAADIWSLGCTVIEMATGRPPFH 573
Query: 1245 NF-EVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPF 1302
AAMFQ+G K PP+P +S Q+FL + FE DP +R +A +L+G PF
Sbjct: 574 ELGSPQAAMFQVGMYKVHPPMPSS----LSAEAQAFLLRTFEPDPRLRASAQTLLGDPF 628
>7300559 [T] KOG4279 Serine/threonine protein kinase
Length = 1310
Score = 176 bits (446), Expect = 2e-43
Identities = 113/300 (37%), Positives = 169/300 (55%), Gaps = 22/300 (7%)
Query: 1012 VVEITDKRTISINKSR---NSRGEYKEFAWIKGEIIGKGSFGAVYLALNVTTGEMLAVKQ 1068
++E+T + + +N S N EY + ++GKG++G VY A + T +A+K+
Sbjct: 550 ILEMTADQVVFVNLSNDDANIEYEYDYDEQNRKMVLGKGTYGTVYAARDKQTQVRIAIKE 609
Query: 1069 VTVPEFSSQDESAISMVEALKSEVSTLKDLNHVNIVQYLGFEEKNGIYSLFLEYVAGGSV 1128
V PE +SQD V+ L E+ L H NIV+YLG +NG + +F+E V GGS+
Sbjct: 610 V--PEKNSQD------VQPLHEEIKLHSQLRHRNIVRYLGSCSENGFFKIFMEQVPGGSL 661
Query: 1129 GSLIR-MYGRFDD--QLIRHLTKQVLEGLAYLHSKGILHRDMKADNLLLDN-DGVCKISD 1184
L+ +G D + +KQ+LEGL YLH + I+HRD+K DN+L++ GV KISD
Sbjct: 662 SDLLETKWGPLKDNESTMAFYSKQILEGLKYLHEQDIVHRDIKGDNVLVNTYSGVVKISD 721
Query: 1185 FGISRKSNNIYSNSDMTMRGTVFWMAPEMVDT-AHGYSAKVDIWSLGCVVLEMFAGKRPW 1243
FG S++ I ++ T GT+ +MAPE++D GY DIWS GC +EM GK P+
Sbjct: 722 FGTSKRLARINPMTE-TFTGTLQYMAPEVIDQGVRGYGPAADIWSFGCTNVEMATGKPPF 780
Query: 1244 SNF-EVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPF 1302
AAMF++G K P IP++ +S ++F+ +CF I RP+A L+ PF
Sbjct: 781 IELGSAHAAMFKVGFYKKHPNIPEE----LSANAKNFILRCFAISVMDRPSASQLLEDPF 836
>CE27177 [T] KOG4279 Serine/threonine protein kinase
Length = 1378
Score = 175 bits (443), Expect = 5e-43
Identities = 109/293 (37%), Positives = 167/293 (56%), Gaps = 22/293 (7%)
Query: 1019 RTISINKSRNSRGEYKEFAWIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQD 1078
R +S + R EY+ + ++GKG++G VY A ++ T + VK++ V D
Sbjct: 645 RVLSNPDNEKIRFEYELSNSNERVVLGKGTYGTVYAARDMDTQRQIVVKEIEV----KYD 700
Query: 1079 ESAISMVEALKSEVSTLKDLNHVNIVQYLGFE-----EKNGIYSLFLEYVAGGSVGSLIR 1133
E V+ L E+S L H NIVQYLG + N + +F+E+V GGS+ SL+R
Sbjct: 701 EE----VQPLMEEISLHSTLCHANIVQYLGCDLVGKDGSNDHFLIFMEHVPGGSLSSLLR 756
Query: 1134 M-YGRFDDQLIRHLTKQVLEGLAYLHSKGILHRDMKADNLLLDN-DGVCKISDFGISRKS 1191
+G ++ + + KQ+LEGL YLH I+HRD+K DN+L++ GVCKISDFG ++
Sbjct: 757 SKWGPMNENAMNYYGKQILEGLKYLHELKIVHRDIKGDNVLVNTYSGVCKISDFGTCKRL 816
Query: 1192 NNIYSNSDMTMRGTVFWMAPEMVDTA-HGYSAKVDIWSLGCVVLEMFAGKRPWSNFE-VV 1249
+ ++ T GT+ +MAPE++D GY A DIWS GC ++EM G+ P+ +
Sbjct: 817 AGLNPVTE-TFTGTLQYMAPEVIDHGQRGYGAPADIWSFGCTMVEMATGRPPFVEMQNPQ 875
Query: 1250 AAMFQIGKSKTAPPIPDDTKDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPF 1302
AAMF++G KT PPIP + ++ ++F+ CF + RP+A L+ PF
Sbjct: 876 AAMFRVGMFKTHPPIPTE----ITEKCRNFIKSCFLPEACDRPSAKDLLQDPF 924
>Hs6031180 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and related
serine/threonine protein kinases
Length = 1558
Score = 171 bits (434), Expect = 5e-42
Identities = 100/275 (36%), Positives = 148/275 (53%), Gaps = 19/275 (6%)
Query: 1036 FAWIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTL 1095
F W +G IG+G +G VY ++V TGE++A+K++ F D I + E+
Sbjct: 1291 FKWQRGNKIGEGQYGKVYTCISVDTGELMAMKEI---RFQPNDHKTI---KETADELKIF 1344
Query: 1096 KDLNHVNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLA 1155
+ + H N+V+Y G E +F+EY G++ + R+ + +IR +KQ+ +
Sbjct: 1345 EGIKHPNLVRYFGVELHREEMYIFMEYCDEGTLEEVSRL--GLQEHVIRLYSKQITIAIN 1402
Query: 1156 YLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNN---IYSNSDMTMRGTVFWMAPE 1212
LH GI+HRD+K N+ L + G+ K+ DFG S K N + GT +MAPE
Sbjct: 1403 VLHEHGIVHRDIKGANIFLTSSGLIKLGDFGCSVKLKNNAQTMPGEVNSTLGTAAYMAPE 1462
Query: 1213 MVDTA--HGYSAKVDIWSLGCVVLEMFAGKRPWSNFE-VVAAMFQIGKSKTAPPIPDDTK 1269
++ A G+ DIWSLGCVV+EM GKRPW +E M+++G PPIP
Sbjct: 1463 VITRAKGEGHGRAADIWSLGCVVIEMVTGKRPWHEYEHNFQIMYKVGMGH-KPPIP---- 1517
Query: 1270 DLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPFCK 1304
+ +SP G+ FL C E DP+MR TA L+ H F K
Sbjct: 1518 ERLSPEGKDFLSHCLESDPKMRWTASQLLDHSFVK 1552
>Hs5803088 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and related
serine/threonine protein kinases
Length = 1607
Score = 171 bits (434), Expect = 5e-42
Identities = 100/275 (36%), Positives = 148/275 (53%), Gaps = 19/275 (6%)
Query: 1036 FAWIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTL 1095
F W +G IG+G +G VY ++V TGE++A+K++ F D I + E+
Sbjct: 1340 FKWQRGNKIGEGQYGKVYTCISVDTGELMAMKEI---RFQPNDHKTI---KETADELKIF 1393
Query: 1096 KDLNHVNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLA 1155
+ + H N+V+Y G E +F+EY G++ + R+ + +IR +KQ+ +
Sbjct: 1394 EGIKHPNLVRYFGVELHREEMYIFMEYCDEGTLEEVSRL--GLQEHVIRLYSKQITIAIN 1451
Query: 1156 YLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNN---IYSNSDMTMRGTVFWMAPE 1212
LH GI+HRD+K N+ L + G+ K+ DFG S K N + GT +MAPE
Sbjct: 1452 VLHEHGIVHRDIKGANIFLTSSGLIKLGDFGCSVKLKNNAQTMPGEVNSTLGTAAYMAPE 1511
Query: 1213 MVDTA--HGYSAKVDIWSLGCVVLEMFAGKRPWSNFE-VVAAMFQIGKSKTAPPIPDDTK 1269
++ A G+ DIWSLGCVV+EM GKRPW +E M+++G PPIP
Sbjct: 1512 VITRAKGEGHGRAADIWSLGCVVIEMVTGKRPWHEYEHNFQIMYKVGMGH-KPPIP---- 1566
Query: 1270 DLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPFCK 1304
+ +SP G+ FL C E DP+MR TA L+ H F K
Sbjct: 1567 ERLSPEGKDFLSHCLESDPKMRWTASQLLDHSFVK 1601
>7300435 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and related
serine/threonine protein kinases
Length = 1612
Score = 170 bits (430), Expect = 2e-41
Identities = 102/302 (33%), Positives = 162/302 (52%), Gaps = 23/302 (7%)
Query: 1015 ITDKRTISINKSRNS------RGEYKEFAWIKGEIIGKGSFGAVYLALNVTTGEMLAVKQ 1068
+ ++R I KS NS R F W +G IG+G FG VY A+N TGE++A+K+
Sbjct: 1294 LRERRLIGQVKSLNSSDKVHIRARSVHFRWHRGIKIGQGRFGKVYTAVNNNTGELMAMKE 1353
Query: 1069 VTVPEFSSQDESAISMVEALKSEVSTLKDLNHVNIVQYLGFEEKNGIYSLFLEYVAGGSV 1128
+ + ++ ++ + E+ L+ + H N+V+Y G E +F+E + G++
Sbjct: 1354 IAIQPGETR------ALKNVAEELKILEGIKHKNLVRYYGIEVHREELLIFMELCSEGTL 1407
Query: 1129 GSLIRMYGRFDDQLIRHLTKQVLEGLAYLHSKGILHRDMKADNL-LLDNDGVCKISDFG- 1186
SL+ + G + L R T Q+L G++ LH GI+HRD+K N+ L+D K+ DFG
Sbjct: 1408 ESLVELTGNLPEALTRRFTAQLLSGVSELHKHGIVHRDIKTANIFLVDGSNSLKLGDFGS 1467
Query: 1187 -ISRKSNNIYSNSDMTMRGTVFWMAPEMV--DTAHGYSAKVDIWSLGCVVLEMFAGKRPW 1243
+ +++ GT +MAPE+ + G+ DIWS+GCVV+EM +GKRPW
Sbjct: 1468 AVKIQAHTTVPGELQGYVGTQAYMAPEVFTKTNSDGHGRAADIWSVGCVVVEMASGKRPW 1527
Query: 1244 SNFEV-VAAMFQIGKSKTAPPIPDDTKDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPF 1302
+ F+ MF++G + P P+ +S G F+D C + DP+ R TA L+ H F
Sbjct: 1528 AQFDSNFQIMFKVGMGE-KPQAPES----LSQEGHDFIDHCLQHDPKRRLTAVELLEHNF 1582
Query: 1303 CK 1304
CK
Sbjct: 1583 CK 1584
>At1g69220 [T] KOG0576 Mitogen-activated protein kinase kinase kinase kinase
(MAP4K) germinal center kinase family
Length = 836
Score = 165 bits (417), Expect = 5e-40
Identities = 111/363 (30%), Positives = 187/363 (50%), Gaps = 29/363 (7%)
Query: 979 KTIRIIAQEASEARKNEVSQKLQRKNTKMWGTKVVEITDKRTISINKSRNSRGEYKEFAW 1038
KT ++ +S E ++K+Q++N+KM T S+ S ++ +
Sbjct: 203 KTRKLDPSSSSSKLHGEDNRKMQQQNSKM-----------STTSLPDSITREDPTTKYEF 251
Query: 1039 IKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDL 1098
+ +GKGS+G+VY A ++ T E++AVK +++ E E ++ E+ L+
Sbjct: 252 LNE--LGKGSYGSVYKARDLKTSEIVAVKVISLTEGEEG-------YEEIRGEIEMLQQC 302
Query: 1099 NHVNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGR-FDDQLIRHLTKQVLEGLAYL 1157
NH N+V+YLG + + +EY GGSV L+ + ++ I ++ ++ L+GLAYL
Sbjct: 303 NHPNVVRYLGSYQGEDYLWIVMEYCGGGSVADLMNVTEEALEEYQIAYICREALKGLAYL 362
Query: 1158 HSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVDTA 1217
HS +HRD+K N+LL G K+ DFG++ + S + T GT WMAPE++
Sbjct: 363 HSIYKVHRDIKGGNILLTEQGEVKLGDFGVAAQLTRTMSKRN-TFIGTPHWMAPEVIQ-E 420
Query: 1218 HGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQ 1277
+ Y KVD+W+LG +EM G P S+ + +F I + AP + D K+ S
Sbjct: 421 NRYDGKVDVWALGVSAIEMAEGLPPRSSVHPMRVLFMI-SIEPAPMLED--KEKWSLVFH 477
Query: 1278 SFLDQCFEIDPEMRPTADSLVGHPF---CKTSSSFDFPKTKLAQFIKSNDKLNSSRLRIS 1334
F+ +C +P +RPTA ++ H F CKT +S PK + ++ I++ L + +
Sbjct: 478 DFVAKCLTKEPRLRPTAAEMLKHKFVERCKTGASAMSPKIEKSRQIRATMALQAQSVVAP 537
Query: 1335 SQE 1337
S E
Sbjct: 538 SLE 540
>Hs4505599 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 525
Score = 162 bits (409), Expect = 4e-39
Identities = 108/369 (29%), Positives = 189/369 (50%), Gaps = 30/369 (8%)
Query: 944 SLKTKSEQQPAFLSSRGESSQFLTPVKSLKPPKRTKTIRI------IAQEASEARKNEVS 997
+L K + PA ++ + + P P TK+I + ++ + +
Sbjct: 156 ALNAKGTEAPAVVTEEEDDDEETAPPVIAPRPDHTKSIYTRSVIDPVPAPVGDSHVDGAA 215
Query: 998 QKL--QRKNTKMWGTKVVEITDKRTISINKSRNSRGEYKEFAWIKGEIIGKGSFGAVYLA 1055
+ L Q+K KM +++E + +SI + Y++ IG+G+ G V+ A
Sbjct: 216 KSLDKQKKKPKMTDEEIMEKL-RTIVSIGDPKKKYTRYEK--------IGQGASGTVFTA 266
Query: 1056 LNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHVNIVQYLGFEEKNGI 1115
+V G+ +A+KQ+ + + + E + +E+ +K+L + NIV +L
Sbjct: 267 TDVALGQEVAIKQINLQKQPKK--------ELIINEILVMKELKNPNIVNFLDSYLVGDE 318
Query: 1116 YSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHSKGILHRDMKADNLLLD 1175
+ +EY+AGGS+ ++ D+ I + ++ L+ L +LH+ ++HRD+K+DN+LL
Sbjct: 319 LFVVMEYLAGGSLTDVVTETACMDEAQIAAVCRECLQALEFLHANQVIHRDIKSDNVLLG 378
Query: 1176 NDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVDTAHGYSAKVDIWSLGCVVLE 1235
+G K++DFG + S TM GT +WMAPE+V T Y KVDIWSLG + +E
Sbjct: 379 MEGSVKLTDFGFCAQITPEQSKRS-TMVGTPYWMAPEVV-TRKAYGPKVDIWSLGIMAIE 436
Query: 1236 MFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQSFLDQCFEIDPEMRPTAD 1295
M G+ P+ N + A++ I + T P + + K +SP + FL++C E+D E R +A
Sbjct: 437 MVEGEPPYLNENPLRALYLIATNGT-PELQNPEK--LSPIFRDFLNRCLEMDVEKRGSAK 493
Query: 1296 SLVGHPFCK 1304
L+ HPF K
Sbjct: 494 ELLQHPFLK 502
>SPAC2C4.14c [T] KOG0201 Serine/threonine protein kinase
Length = 312
Score = 161 bits (407), Expect = 7e-39
Identities = 101/290 (34%), Positives = 158/290 (53%), Gaps = 17/290 (5%)
Query: 1042 EIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHV 1101
++IG+GSFG+V+ A +V + +++A+K V + Q +E L E++ L DLN V
Sbjct: 10 QLIGQGSFGSVFRAQDVESSKIVALKVVDLDATKDQ-------IETLTQEINFLIDLNSV 62
Query: 1102 NIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHSKG 1161
+I +Y + +EY GGS L+++ G F +++I + +QVLE L YLH +G
Sbjct: 63 HITKYYASFVDGFRLWITMEYCDGGSCLDLLKLSGTFSERVIAEVMRQVLEALVYLHGQG 122
Query: 1162 ILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVDTAHGYS 1221
+HRD+KA N+L DG+ K++DFG+S + ++ +D GT FWMAPE+V GY+
Sbjct: 123 KMHRDIKAANILTMKDGLVKLADFGVSGQLESLRDKND-DFVGTPFWMAPEVVKQT-GYN 180
Query: 1222 AKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQSFLD 1281
K DIWSLG E+ G+ P+S + + I K +PP + +K S A F+
Sbjct: 181 YKADIWSLGITAYELATGEPPYSGIHPMKVLLLI--PKHSPPSLERSK--FSRAFCDFVS 236
Query: 1282 QCFEIDPEMRPTADSLVGHPFCKTSSSFDFPKTKLAQFIKSNDKLNSSRL 1331
C + +P+ R TA+ L H F K P T + + + S K S L
Sbjct: 237 NCLKKNPKDRATAEYLSKHKFIKKYC----PNTSVKEVVASYAKWKESEL 282
>At4g26890 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 444
Score = 160 bits (406), Expect = 1e-38
Identities = 103/276 (37%), Positives = 159/276 (57%), Gaps = 33/276 (11%)
Query: 1035 EFAWIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVST 1094
E W +G IIG+GS V +A++ ++GE+ AVK S D S+ S+ L+ E S
Sbjct: 2 EINWTRGPIIGRGSTATVSIAIS-SSGELFAVK--------SADLSSSSL---LQKEQSI 49
Query: 1095 LKDLNHVNIVQYLGF---EEKNG-IYSLFLEYVAGGSVGSLIRMYG-RFDDQLIRHLTKQ 1149
L L+ ++V+Y+G E NG +Y++ +EYV+GG++ LI+ G + + IR T+Q
Sbjct: 50 LSTLSSPHMVKYIGTGLTRESNGLVYNILMEYVSGGNLHDLIKNSGGKLPEPEIRSYTRQ 109
Query: 1150 VLEGLAYLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWM 1209
+L GL YLH +GI+H D+K+ N+L++ +GV KI+D G ++ S GT +M
Sbjct: 110 ILNGLVYLHERGIVHCDLKSHNVLVEENGVLKIADMGCAK------SVDKSEFSGTPAFM 163
Query: 1210 APEMVDTAHGYSAK--VDIWSLGCVVLEMFAGKRPWSNF-EVVAAMFQIGKSKTAPPIPD 1266
APE+ A G + D+W+LGC ++EM G PW +VVAAM++IG S +P IP
Sbjct: 164 APEV---ARGEEQRFPADVWALGCTMIEMMTGSSPWPELNDVVAAMYKIGFSGESPAIP- 219
Query: 1267 DTKDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPF 1302
+S + FL C + D + R T + L+ HPF
Sbjct: 220 ---AWISDKAKDFLKNCLKEDQKQRWTVEELLKHPF 252
>YAR019c [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 974
Score = 160 bits (404), Expect = 2e-38
Identities = 101/295 (34%), Positives = 155/295 (52%), Gaps = 20/295 (6%)
Query: 1020 TISINKSRNSRGEYKEFAWIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDE 1079
T +N + R K + ++IG+GS+G VY A+N T +++A+K+V + + +E
Sbjct: 7 TDRVNLTPIQRASEKSVQYHLKQVIGRGSYGVVYKAINKHTDQVVAIKEVV---YENDEE 63
Query: 1080 SAISMVEALKSEVSTLKDLNHVNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLI-RMYGRF 1138
+ + +E+S LK+LNH NIV+Y GF K+ + LEY A GS+ LI R
Sbjct: 64 -----LNDIMAEISLLKNLNHNNIVKYHGFIRKSYELYILLEYCANGSLRRLISRSSTGL 118
Query: 1139 DDQLIRHLTKQVLEGLAYLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNS 1198
+ + Q L GL YLH +G++HRD+KA N+LL D K++DFG+S I ++S
Sbjct: 119 SENESKTYVTQTLLGLKYLHGEGVIHRDIKAANILLSADNTVKLADFGVS----TIVNSS 174
Query: 1199 DMTMRGTVFWMAPEMVDTAHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKS 1258
+T+ GT+ WMAPE++ G S DIWSLG V+EM P+ N + +
Sbjct: 175 ALTLAGTLNWMAPEILGN-RGASTLSDIWSLGATVVEMLTKNPPYHNLTDANIYYAVEND 233
Query: 1259 KTAPPIPDDTKDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPFCKTSSSFDFPK 1313
PP S + FL +CF + RPTAD L+ H + ++ + K
Sbjct: 234 TYYPP------SSFSEPLKDFLSKCFVKNMYKRPTADQLLKHVWINSTENVKVDK 282
>SPAC9G1.09 [T] KOG0201 Serine/threonine protein kinase
Length = 471
Score = 159 bits (402), Expect = 3e-38
Identities = 96/267 (35%), Positives = 157/267 (57%), Gaps = 18/267 (6%)
Query: 1044 IGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHVNI 1103
+G GSFG V+ A +G+++A+KQ+ + E+ I + ++ EV L + N N+
Sbjct: 15 LGSGSFGVVWKARENVSGDIIAIKQIDL-------ETGIDDITDIEQEVFMLSNCNSSNV 67
Query: 1104 VQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHSKGIL 1163
+QY G + +E++ GGSV L++M GR ++Q+I + ++VL GL YLH + +
Sbjct: 68 IQYYGCFVDGYTLWILMEHMDGGSVSGLLKM-GRLNEQVISIILREVLYGLNYLHGQNKI 126
Query: 1164 HRDMKADNLLLDND-GVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMV-DTAHGYS 1221
HRD+KA N+LL + G K++DFG++ + +N S T GT FWMAPE++ T++G +
Sbjct: 127 HRDIKAANILLSSSTGNVKLADFGVAAQLSNAASRRH-TFVGTPFWMAPEVIQQTSYGLA 185
Query: 1222 AKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQSFLD 1281
A DIWSLG +EM G P + + +F+I +S+ PP DD SP + F+
Sbjct: 186 A--DIWSLGITAIEMANGIPPRATMHPMRVIFEIPQSE--PPKLDDH---FSPTFRDFVS 238
Query: 1282 QCFEIDPEMRPTADSLVGHPFCKTSSS 1308
C +++P MR +A L+ HPF K++ +
Sbjct: 239 CCLDLNPNMRWSAKELLQHPFIKSAGT 265
>At5g55090 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 448
Score = 159 bits (402), Expect = 3e-38
Identities = 112/318 (35%), Positives = 168/318 (52%), Gaps = 49/318 (15%)
Query: 1034 KEFAWIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVS 1093
+E WI+G IIG+GS V L + +G+ AVK EFSS L+ E S
Sbjct: 2 EEQNWIRGPIIGRGSTATVSLGIT-NSGDFFAVKSA---EFSSS--------AFLQREQS 49
Query: 1094 TLKDLNHVNIVQYLGF----EEKNGIYSLFLEYVAGGSVGSLIRMYG-RFDDQLIRHLTK 1148
L L+ IV+Y+G E +Y+L +EYV+GGS+ LI+ G + + LIR T+
Sbjct: 50 ILSKLSSPYIVKYIGSNVTKENDKLMYNLLMEYVSGGSLHDLIKNSGGKLPEPLIRSYTR 109
Query: 1149 QVLEGLAYLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFW 1208
Q+L+GL YLH +GI+H D+K+ N+++ + + KI D G ++ + N ++ GT +
Sbjct: 110 QILKGLMYLHDQGIVHCDVKSQNVMIGGE-IAKIVDLGCAK---TVEENENLEFSGTPAF 165
Query: 1209 MAPEMVDTAHGYSAKVDIWSLGCVVLEMFAGKRPWSNF-EVVAAMFQIGKSKTAPPIPDD 1267
M+PE V S D+W+LGC V+EM G PW +VVAA+++IG + +P IP
Sbjct: 166 MSPE-VARGEEQSFPADVWALGCTVIEMATGSSPWPELNDVVAAIYKIGFTGESPVIP-- 222
Query: 1268 TKDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPF-------------CKTSSS------ 1308
+S GQ FL +C DP+ R T + L+ HPF C SSS
Sbjct: 223 --VWLSEKGQDFLRKCLRKDPKQRWTVEELLQHPFLDEEDNDSDQTGNCLNSSSPSTVLD 280
Query: 1309 ---FDFPKTKLAQFIKSN 1323
+D +T ++FIK +
Sbjct: 281 QRFWDLCETSRSRFIKED 298
>At3g15220 [T] KOG0201 Serine/threonine protein kinase
Length = 690
Score = 159 bits (401), Expect = 4e-38
Identities = 93/265 (35%), Positives = 145/265 (54%), Gaps = 13/265 (4%)
Query: 1042 EIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHV 1101
E+IG+GSFG VY A + + +A+K + + E S+DE +E ++ E+S L
Sbjct: 19 ELIGRGSFGDVYKAFDKDLNKEVAIKVIDLEE--SEDE-----IEDIQKEISVLSQCRCP 71
Query: 1102 NIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHSKG 1161
I +Y G + +EY+AGGSV L++ D+ I +T+ +L + YLH++G
Sbjct: 72 YITEYYGSYLHQTKLWIIMEYMAGGSVADLLQSNNPLDETSIACITRDLLHAVEYLHNEG 131
Query: 1162 ILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVDTAHGYS 1221
+HRD+KA N+LL +G K++DFG+S + S T GT FWMAPE++ + GY+
Sbjct: 132 KIHRDIKAANILLSENGDVKVADFGVSAQLTRTISRR-KTFVGTPFWMAPEVIQNSEGYN 190
Query: 1222 AKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQSFLD 1281
K DIWSLG V+EM G+ P ++ + +F I + PP D+ S + F+
Sbjct: 191 EKADIWSLGITVIEMAKGEPPLADLHPMRVLFII--PRETPPQLDEH---FSRQVKEFVS 245
Query: 1282 QCFEIDPEMRPTADSLVGHPFCKTS 1306
C + P RP+A L+ H F K +
Sbjct: 246 LCLKKAPAERPSAKELIKHRFIKNA 270
>Hs5454096 [T] KOG0574 STE20-like serine/threonine kinase MST
Length = 487
Score = 158 bits (399), Expect = 6e-38
Identities = 96/297 (32%), Positives = 160/297 (53%), Gaps = 16/297 (5%)
Query: 1042 EIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHV 1101
E +G+GS+G+VY A++ TG+++A+KQV V S ++ + E+S ++ +
Sbjct: 34 EKLGEGSYGSVYKAIHKETGQIVAIKQVPVE----------SDLQEIIKEISIMQQCDSP 83
Query: 1102 NIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGR-FDDQLIRHLTKQVLEGLAYLHSK 1160
++V+Y G KN + +EY GSV +IR+ + + I + + L+GL YLH
Sbjct: 84 HVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFM 143
Query: 1161 GILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVDTAHGY 1220
+HRD+KA N+LL+ +G K++DFG++ + + + + T+ GT FWMAPE++ GY
Sbjct: 144 RKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKRN-TVIGTPFWMAPEVIQEI-GY 201
Query: 1221 SAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQSFL 1280
+ DIWSLG +EM GK P+++ + A+F I T PP +L S F+
Sbjct: 202 NCVADIWSLGITAIEMAEGKPPYADIHPMRAIFMI---PTNPPPTFRKPELWSDNFTDFV 258
Query: 1281 DQCFEIDPEMRPTADSLVGHPFCKTSSSFDFPKTKLAQFIKSNDKLNSSRLRISSQE 1337
QC PE R TA L+ HPF +++ + + + + K S+ R Q+
Sbjct: 259 KQCLVKSPEQRATATQLLQHPFVRSAKGVSILRDLINEAMDVKLKRQESQQREVDQD 315
>Hs15011880 [T] KOG0201 Serine/threonine protein kinase
Length = 416
Score = 158 bits (399), Expect = 6e-38
Identities = 95/273 (34%), Positives = 151/273 (54%), Gaps = 15/273 (5%)
Query: 1035 EFAWIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVST 1094
E + K E IGKGSFG V+ ++ T +++A+K + + E ++DE +E ++ E++
Sbjct: 21 EELFTKLERIGKGSFGEVFKGIDNRTQQVVAIKIIDLEE--AEDE-----IEDIQQEITV 73
Query: 1095 LKDLNHVNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGL 1154
L + + +Y G K + +EY+ GGS L+R G FD+ I + K++L+GL
Sbjct: 74 LSQCDSSYVTKYYGSYLKGSKLWIIMEYLGGGSALDLLRA-GPFDEFQIATMLKEILKGL 132
Query: 1155 AYLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMV 1214
YLHS+ +HRD+KA N+LL G K++DFG++ + + + T GT FWMAPE++
Sbjct: 133 DYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRN-TFVGTPFWMAPEVI 191
Query: 1215 DTAHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSP 1274
+ Y +K DIWSLG +E+ G+ P S+ + +F I K+ + D TK
Sbjct: 192 QQS-AYDSKADIWSLGITAIELAKGEPPNSDMHPMRVLFLIPKNNPPTLVGDFTKSF--- 247
Query: 1275 AGQSFLDQCFEIDPEMRPTADSLVGHPFCKTSS 1307
+ F+D C DP RPTA L+ H F +S
Sbjct: 248 --KEFIDACLNKDPSFRPTAKELLKHKFIVKNS 278
>At1g53165 [T] KOG0201 Serine/threonine protein kinase
Length = 1007
Score = 157 bits (397), Expect = 1e-37
Identities = 101/308 (32%), Positives = 164/308 (52%), Gaps = 21/308 (6%)
Query: 1000 LQRKNTKMWGTKVVEITDKRTIS-INKSRNSRGEYKEFAWIKGEIIGKGSFGAVYLALNV 1058
L K K G KVV + + ++ + ++ +R + +F E+IG+GSFG VY A +
Sbjct: 310 LDSKLVKFRGKKVVLVVEMDDVAGLQEAAGTR--FSQF-----ELIGRGSFGDVYKAFDT 362
Query: 1059 TTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHVNIVQYLGFEEKNGIYSL 1118
+ +A+K + + E S+DE +E ++ E+S L I +Y G +
Sbjct: 363 ELNKDVAIKVIDLEE--SEDE-----IEDIQKEISVLSQCRCPYITEYYGSYLHQTKLWI 415
Query: 1119 FLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHSKGILHRDMKADNLLLDNDG 1178
+EY+AGGSV L++ D+ I +T+ +L + YLH++G +HRD+KA N+LL +G
Sbjct: 416 IMEYMAGGSVADLLQPGNPLDEISIACITRDLLHAVEYLHAEGKIHRDIKAANILLSENG 475
Query: 1179 VCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVDTAHGYSAKVDIWSLGCVVLEMFA 1238
K++DFG+S + S T GT FWMAPE++ + GY+ K DIWSLG ++EM
Sbjct: 476 DVKVADFGVSAQLTRTISRR-KTFVGTPFWMAPEVIQNSEGYNEKADIWSLGITMIEMAK 534
Query: 1239 GKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQSFLDQCFEIDPEMRPTADSLV 1298
G+ P ++ + +F I + +PP D+ S + F+ C + P RP A L+
Sbjct: 535 GEPPLADLHPMRVLFII--PRESPPQLDEH---FSRPLKEFVSFCLKKAPAERPNAKELL 589
Query: 1299 GHPFCKTS 1306
H F K +
Sbjct: 590 KHRFIKNA 597
>YHR102w [T] KOG0201 Serine/threonine protein kinase
Length = 1080
Score = 156 bits (395), Expect = 2e-37
Identities = 102/295 (34%), Positives = 163/295 (54%), Gaps = 17/295 (5%)
Query: 1042 EIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHV 1101
E+IG+G FG VY NV TG + A+K + + S DE VE ++ E+ L L +
Sbjct: 27 EVIGRGKFGVVYKGYNVKTGRVYAIKVLNLD--SDSDE-----VEDVQREIQFLASLKQI 79
Query: 1102 -NIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHSK 1160
NI +Y G K+ + +E+ AGGS+ SL+R G+ D++ I + +++L L +H
Sbjct: 80 SNITRYYGSYLKDTSLWIIMEHCAGGSLRSLLRP-GKIDEKYIGVIMRELLVALKCIHKD 138
Query: 1161 GILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVDTAHGY 1220
++HRD+KA N+L+ N+G K+ DFG++ + N S TM GT +WMAPE++ Y
Sbjct: 139 NVIHRDIKAANVLITNEGNVKLCDFGVAAQVNQT-SLRRQTMAGTPYWMAPEVIMEGVYY 197
Query: 1221 SAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQSFL 1280
KVDIWSLG E+ G P+ + E + AM I KSK PP +D S + + F+
Sbjct: 198 DTKVDIWSLGITTYEIATGNPPYCDVEALRAMQLIIKSK--PPRLEDRS--YSTSLKEFI 253
Query: 1281 DQCFEIDPEMRPTADSLVGHPFCKT--SSSFDFPKTKLAQFIKSNDKLNSSRLRI 1333
C + DP+ R +AD L+ F + ++ K +++++ DK N ++ +I
Sbjct: 254 ALCLDEDPKERLSADDLLKSKFIRAHKATPTSILKELISRYLLFRDK-NKNKYKI 307
>7298926 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 704
Score = 156 bits (395), Expect = 2e-37
Identities = 100/301 (33%), Positives = 168/301 (55%), Gaps = 15/301 (4%)
Query: 1004 NTKMWGTKVVEITDKRTISINKSRNSRGEYKEFAWIKGEIIGKGSFGAVYLALNVTTGEM 1063
NT+ K +++D+ + ++ S G+ + K E IG+G+ G VY A+ +TG
Sbjct: 397 NTRAANAKKKKMSDEEILEKLRTIVSVGDPNR-KYTKMEKIGQGASGTVYTAIESSTGME 455
Query: 1064 LAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHVNIVQYLGFEEKNGIYSLFLEYV 1123
+A+KQ+ + + + E + +E+ +++ H N+V YL + + +EY+
Sbjct: 456 VAIKQMNLSQQPKK--------ELIINEILVMRENKHPNVVNYLDSYLVSEELWVVMEYL 507
Query: 1124 AGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHSKGILHRDMKADNLLLDNDGVCKIS 1183
GGS+ ++ D+ I + ++VL+ L +LH+ ++HRD+K+DN+LL DG K++
Sbjct: 508 PGGSLTDVVTETC-MDEGQIAAVCREVLQALEFLHANQVIHRDIKSDNILLGLDGSVKLT 566
Query: 1184 DFGISRKSNNIYSNSDMTMRGTVFWMAPEMVDTAHGYSAKVDIWSLGCVVLEMFAGKRPW 1243
DFG + + S TM GT +WMAPE+V T Y KVD+WSLG + +EM G+ P+
Sbjct: 567 DFGFCAQISPEQSKR-TTMVGTPYWMAPEVV-TRKQYGPKVDLWSLGIMAIEMVEGEPPY 624
Query: 1244 SNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPFC 1303
N + A++ I + P I + KD +S A Q FLDQC E++ + R +A L+ HPF
Sbjct: 625 LNENPLKALYLIA-TNGKPEIKE--KDKLSSAFQDFLDQCLEVEVDRRASALDLLKHPFL 681
Query: 1304 K 1304
K
Sbjct: 682 K 682
>7300224 [T] KOG0201 Serine/threonine protein kinase
Length = 642
Score = 155 bits (393), Expect = 3e-37
Identities = 94/270 (34%), Positives = 150/270 (54%), Gaps = 15/270 (5%)
Query: 1035 EFAWIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVST 1094
E + K E IGKGSFG V+ ++ T +++A+K + + E ++DE ++ ++ E+
Sbjct: 10 ELIFTKQERIGKGSFGEVFKGIDNRTQQVVAIKIIDLEE--AEDE-----IDDIQQEIMV 62
Query: 1095 LKDLNHVNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGL 1154
L + + +Y G K + +EY+ GGS L++ G F++ I + ++VL+GL
Sbjct: 63 LSQCDSPYVTKYYGSFLKGTKLWIIMEYLGGGSALDLMKA-GSFEEMHIGIILREVLKGL 121
Query: 1155 AYLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMV 1214
YLHS+ LHRD+KA N+LL G K++DFG++ + N S + T GT FWMAPE++
Sbjct: 122 DYLHSERKLHRDIKAANVLLSEQGDVKLADFGVAGQLTNTTSKRN-TFVGTPFWMAPEVI 180
Query: 1215 DTAHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSP 1274
+ Y AK DIWSLG +E+ G+ P S + +F I K+ P +
Sbjct: 181 KQSQ-YDAKADIWSLGITAIELAKGEPPNSELHPMRVLFLIPKNN-----PPQLTGSYTK 234
Query: 1275 AGQSFLDQCFEIDPEMRPTADSLVGHPFCK 1304
+ + F++ C DPE RPTA L+ +PF K
Sbjct: 235 SFKDFVEACLNKDPENRPTAKELLKYPFIK 264
>Hs7382496 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 545
Score = 155 bits (392), Expect = 4e-37
Identities = 107/352 (30%), Positives = 185/352 (52%), Gaps = 16/352 (4%)
Query: 953 PAFLSSRGESSQFLTPVKSLKPPKRTKTIRIIAQEASEARKNEVSQKLQRKNTKMWGTKV 1012
P ++ R E ++ + ++P T T + S N +NT+ K
Sbjct: 187 PPVIAPRPEHTKSVYTRSVIEPLPVTPTRDVATSPISPTENNTTPPDALTRNTEKQKKKP 246
Query: 1013 VEITDKRTISINKSRNSRGEYKEFAWIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVP 1072
+++D+ + +S S G+ K+ + + E IG+G+ G VY A++V TG+ +A+KQ+ +
Sbjct: 247 -KMSDEEILEKLRSIVSVGDPKK-KYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQ 304
Query: 1073 EFSSQDESAISMVEALKSEVSTLKDLNHVNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLI 1132
+ + E + +E+ +++ + NIV YL + +EY+AGGS+ ++
Sbjct: 305 QQPKK--------ELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVV 356
Query: 1133 RMYGRFDDQLIRHLTKQVLEGLAYLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSN 1192
D+ I + ++ L+ L +LHS ++HRD+K+DN+LL DG K++DFG +
Sbjct: 357 TETC-MDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQIT 415
Query: 1193 NIYSNSDMTMRGTVFWMAPEMVDTAHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAM 1252
S TM GT +WMAPE+V T Y KVDIWSLG + +EM G+ P+ N + A+
Sbjct: 416 PEQSKRS-TMVGTPYWMAPEVV-TRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRAL 473
Query: 1253 FQIGKSKTAPPIPDDTKDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPFCK 1304
+ I + T P + + K +S + FL++C ++D E R +A L+ H F K
Sbjct: 474 YLIATNGT-PELQNPEK--LSAIFRDFLNRCLDMDVEKRGSAKELLQHQFLK 522
>Hs4505601 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 544
Score = 155 bits (392), Expect = 4e-37
Identities = 101/304 (33%), Positives = 168/304 (55%), Gaps = 23/304 (7%)
Query: 1001 QRKNTKMWGTKVVEITDKRTISINKSRNSRGEYKEFAWIKGEIIGKGSFGAVYLALNVTT 1060
QRK +KM +++E + SI + + +Y F E IG+G+ G VY AL++ T
Sbjct: 240 QRKKSKMTDEEILE----KLRSIVSVGDPKKKYTRF-----EKIGQGASGTVYTALDIAT 290
Query: 1061 GEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHVNIVQYLGFEEKNGIYSLFL 1120
G+ +A+KQ+ + + + E + +E+ +++ + NIV YL + +
Sbjct: 291 GQEVAIKQMNLQQQPKK--------ELIINEILVMRENKNPNIVNYLDSYLVGDELWVVM 342
Query: 1121 EYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHSKGILHRDMKADNLLLDNDGVC 1180
EY+AGGS+ ++ D+ I + ++ L+ L +LHS ++HRD+K+DN+LL DG
Sbjct: 343 EYLAGGSLTDVVTETC-MDEGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILLGMDGSV 401
Query: 1181 KISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVDTAHGYSAKVDIWSLGCVVLEMFAGK 1240
K++DFG + S TM GT +WMAPE+V T Y KVDIWSLG + +EM G+
Sbjct: 402 KLTDFGFCAQITPEQSKRS-TMVGTPYWMAPEVV-TRKAYGPKVDIWSLGIMAIEMVEGE 459
Query: 1241 RPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQSFLDQCFEIDPEMRPTADSLVGH 1300
P+ N + A++ I + T P + + + +S + FL++C E+D + R +A L+ H
Sbjct: 460 PPYLNENPLRALYLIATNGT-PELQNPER--LSAVFRDFLNRCLEMDVDRRGSAKELLQH 516
Query: 1301 PFCK 1304
PF K
Sbjct: 517 PFLK 520
>Hs5454094 [T] KOG0574 STE20-like serine/threonine kinase MST
Length = 491
Score = 154 bits (390), Expect = 7e-37
Identities = 95/298 (31%), Positives = 162/298 (53%), Gaps = 18/298 (6%)
Query: 1042 EIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHV 1101
E +G+GS+G+V+ A++ +G+++A+KQV V S ++ + E+S ++ +
Sbjct: 31 EKLGEGSYGSVFKAIHKESGQVVAIKQVPVE----------SDLQEIIKEISIMQQCDSP 80
Query: 1102 NIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGR--FDDQLIRHLTKQVLEGLAYLHS 1159
+V+Y G KN + +EY GSV +IR+ + +D+ I + K L+GL YLH
Sbjct: 81 YVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLIEDE-IATILKSTLKGLEYLHF 139
Query: 1160 KGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVDTAHG 1219
+HRD+KA N+LL+ +G K++DFG++ + + + + T+ GT FWMAPE++ G
Sbjct: 140 MRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKRN-TVIGTPFWMAPEVIQEI-G 197
Query: 1220 YSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQSF 1279
Y+ DIWSLG +EM GK P+++ + A+F I T PP +L S F
Sbjct: 198 YNCVADIWSLGITSIEMAEGKPPYADIHPMRAIFMI---PTNPPPTFRKPELWSDDFTDF 254
Query: 1280 LDQCFEIDPEMRPTADSLVGHPFCKTSSSFDFPKTKLAQFIKSNDKLNSSRLRISSQE 1337
+ +C +PE R TA L+ HPF K + + + + ++ K + + R +E
Sbjct: 255 VKKCLVKNPEQRATATQLLQHPFIKNAKPVSILRDLITEAMEIKAKRHDEQQRELEEE 312
>Hs16178962 [T] KOG0574 STE20-like serine/threonine kinase MST
Length = 491
Score = 154 bits (390), Expect = 7e-37
Identities = 95/298 (31%), Positives = 162/298 (53%), Gaps = 18/298 (6%)
Query: 1042 EIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHV 1101
E +G+GS+G+V+ A++ +G+++A+KQV V S ++ + E+S ++ +
Sbjct: 31 EKLGEGSYGSVFKAIHKESGQVVAIKQVPVE----------SDLQEIIKEISIMQQCDSP 80
Query: 1102 NIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGR--FDDQLIRHLTKQVLEGLAYLHS 1159
+V+Y G KN + +EY GSV +IR+ + +D+ I + K L+GL YLH
Sbjct: 81 YVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLIEDE-IATILKSTLKGLEYLHF 139
Query: 1160 KGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVDTAHG 1219
+HRD+KA N+LL+ +G K++DFG++ + + + + T+ GT FWMAPE++ G
Sbjct: 140 MRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKRN-TVIGTPFWMAPEVIQEI-G 197
Query: 1220 YSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQSF 1279
Y+ DIWSLG +EM GK P+++ + A+F I T PP +L S F
Sbjct: 198 YNCVADIWSLGITSIEMAEGKPPYADIHPMRAIFMI---PTNPPPTFRKPELWSDDFTDF 254
Query: 1280 LDQCFEIDPEMRPTADSLVGHPFCKTSSSFDFPKTKLAQFIKSNDKLNSSRLRISSQE 1337
+ +C +PE R TA L+ HPF K + + + + ++ K + + R +E
Sbjct: 255 VKKCLVKNPEQRATATQLLQHPFIKNAKPVSILRDLITEAMEIKAKRHEEQQRELEEE 312
>YPL153c [D] KOG0615 Serine/threonine protein kinase Chk2 and related proteins
Length = 821
Score = 154 bits (388), Expect = 1e-36
Identities = 100/321 (31%), Positives = 167/321 (51%), Gaps = 33/321 (10%)
Query: 1028 NSRGEYKEFAWIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEA 1087
N G +K+F+ I E++G+G+F V A+ TTG+ AVK ++ I ++
Sbjct: 189 NKTGIFKDFSIID-EVVGQGAFATVKKAIERTTGKTFAVKIIS-------KRKVIGNMDG 240
Query: 1088 LKSEVSTLKDLNHVNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLT 1147
+ E+ L+ LNH IV+ GF E Y + +E+V+GG + + +G + R ++
Sbjct: 241 VTRELEVLQKLNHPRIVRLKGFYEDTESYYMVMEFVSGGDLMDFVAAHGAVGEDAGREIS 300
Query: 1148 KQVLEGLAYLHSKGILHRDMKADNLLLDNDG--VCKISDFGISRKSNNIYSNSDMTMRGT 1205
+Q+L + Y+HS GI HRD+K DN+L++ D + KI+DFG+++ N + T GT
Sbjct: 301 RQILTAIKYIHSMGISHRDLKPDNILIEQDDPVLVKITDFGLAKVQGN--GSFMKTFCGT 358
Query: 1206 VFWMAPEMV---DTA---------HGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMF 1253
+ ++APE++ DT+ + YS+ VD+WS+GC+V + G P+S
Sbjct: 359 LAYVAPEVIRGKDTSVSPDEYEERNEYSSLVDMWSMGCLVYVILTGHLPFSGSTQDQLYK 418
Query: 1254 QIGK-SKTAPPIPDDTKDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPFCKTS-----S 1307
QIG+ S P+ D +S + F+D ++DP R TA + HP+ K S S
Sbjct: 419 QIGRGSYHEGPLKDFR---ISEEARDFIDSLLQVDPNNRSTAAKALNHPWIKMSPLGSQS 475
Query: 1308 SFDFPKTKLAQFIKSNDKLNS 1328
DF + L+Q + L +
Sbjct: 476 YGDFSQISLSQSLSQQKLLEN 496
>At1g07150 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 499
Score = 152 bits (383), Expect = 4e-36
Identities = 98/309 (31%), Positives = 163/309 (52%), Gaps = 24/309 (7%)
Query: 1038 WIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKD 1097
W++G IG+G FGAV A++ T GE+ AVK V + S + E+L++E+S +
Sbjct: 23 WVRGACIGRGCFGAVSTAISKTNGEVFAVKSVDLAT------SLPTQSESLENEISVFRS 76
Query: 1098 LN-HVNIVQYLGF----EEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQ-LIRHLTKQVL 1151
L H IV++LG E +L+LEY+ G V S R G+ +D+ L++ T ++
Sbjct: 77 LKPHPYIVKFLGDGVSKEGTTTFRNLYLEYLPNGDVASH-RAGGKIEDETLLQRYTACLV 135
Query: 1152 EGLAYLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAP 1211
L ++HS+G +H D+KA N+L+ + K++DFG + + + + +T RG+ WMAP
Sbjct: 136 SALRHVHSQGFVHCDVKARNILVSQSSMVKLADFGSAFRIHT--PRALITPRGSPLWMAP 193
Query: 1212 EMVDTAHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDL 1271
E++ + + D+WSLGC ++EMF GK W + + ++ +I S P P
Sbjct: 194 EVIRREY-QGPESDVWSLGCTIIEMFTGKPAWED-HGIDSLSRISFSDELPVFPSK---- 247
Query: 1272 VSPAGQSFLDQCFEIDPEMRPTADSLVGHPF---CKTSSSFDFPKTKLAQFIKSNDKLNS 1328
+S G+ FL++C + DP R + D L+ HPF C SS + + ++ S L
Sbjct: 248 LSEIGRDFLEKCLKRDPNQRWSCDQLLQHPFLSQCHNSSPTESSPRCVLDWVNSGFDLEE 307
Query: 1329 SRLRISSQE 1337
+ E
Sbjct: 308 EEEEVGRSE 316
>At5g67080 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 344
Score = 151 bits (382), Expect = 6e-36
Identities = 103/288 (35%), Positives = 160/288 (54%), Gaps = 29/288 (10%)
Query: 1038 WIKGEIIGKGSFGAVYLAL--NVTTGE---MLAVKQVTVPEFSSQDESAISMVEALKSEV 1092
WI+GE IG G+F V LA N +GE ++AVK S D + + KS +
Sbjct: 3 WIRGETIGYGTFSTVSLATRSNNDSGEFPPLMAVK--------SADSYGAASLANEKSVL 54
Query: 1093 STLKDLNHVNIVQYLGFEE--KNG--IYSLFLEYVAGGSVGSLIRMYGR--FDDQLIRHL 1146
L D + IV+ G + +NG +++LFLEY + GS+ S ++ + +R
Sbjct: 55 DNLGD-DCNEIVRCFGEDRTVENGEEMHNLFLEYASRGSLESYLKKLAGEGVPESTVRRH 113
Query: 1147 TKQVLEGLAYLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYS-NSDMTMRGT 1205
T VL GL ++H+ G H D+K N+LL DG KI+DFG++++ ++ + N + +RGT
Sbjct: 114 TGSVLRGLRHIHANGFAHCDLKLGNILLFGDGAVKIADFGLAKRIGDLTALNYGVQIRGT 173
Query: 1206 VFWMAPEMVDTAHGYSAKVDIWSLGCVVLEMFAGKRPWSNFE---VVAAMFQIGKSKTAP 1262
+MAPE V+ + Y ++ D+W+LGCVV+EMF+GK WS E ++ + +IG P
Sbjct: 174 PLYMAPESVND-NEYGSEGDVWALGCVVVEMFSGKTAWSLKEGSNFMSLLLRIGVGDEVP 232
Query: 1263 PIPDDTKDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPFCKTSSSFD 1310
IP++ +S G+ FL +CF DP+ R TA+ L+ HPF D
Sbjct: 233 MIPEE----LSEQGRDFLSKCFVKDPKKRWTAEMLLNHPFVTVDVDHD 276
>CE28674 [T] KOG0201 Serine/threonine protein kinase
Length = 651
Score = 151 bits (381), Expect = 8e-36
Identities = 89/270 (32%), Positives = 149/270 (54%), Gaps = 14/270 (5%)
Query: 1035 EFAWIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVST 1094
E + K E IG+GSFG VY ++ TG ++A+K + + + ++DE +E ++ E+
Sbjct: 29 EVIFTKQERIGRGSFGEVYKGIDNRTGRVVAIKIIDLEQ--AEDE-----IEDIQQEIQV 81
Query: 1095 LKDLNHVNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGL 1154
L + + +Y G K + +EY+ GGS L + G+ D+ I + +++L+GL
Sbjct: 82 LSQCDSQYVTKYFGSFLKGSKLWIIMEYLGGGSALDLTKS-GKLDESHIAVILREILKGL 140
Query: 1155 AYLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMV 1214
YLHS+ +HRD+KA N+L+ G K++DFG++ + +T G+ FWMAPE++
Sbjct: 141 EYLHSERKIHRDIKAANVLVSEHGDVKVADFGVAGQLTETVKKR-ITFVGSPFWMAPELI 199
Query: 1215 DTAHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSP 1274
+ Y K DIWSLG +E+ G+ P S+ + +F I K PP+ ++ S
Sbjct: 200 KQS-SYDYKADIWSLGITAIELANGEPPHSDLHPMRVLFLI--PKNPPPVLQGSQ--WSK 254
Query: 1275 AGQSFLDQCFEIDPEMRPTADSLVGHPFCK 1304
+ F++ C DPE RP+A +L+ H F K
Sbjct: 255 PFKEFVEMCLNKDPENRPSASTLLKHQFIK 284
>CE07510 [T] KOG0201 Serine/threonine protein kinase
Length = 653
Score = 151 bits (381), Expect = 8e-36
Identities = 89/270 (32%), Positives = 149/270 (54%), Gaps = 14/270 (5%)
Query: 1035 EFAWIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVST 1094
E + K E IG+GSFG VY ++ TG ++A+K + + + ++DE +E ++ E+
Sbjct: 31 EVIFTKQERIGRGSFGEVYKGIDNRTGRVVAIKIIDLEQ--AEDE-----IEDIQQEIQV 83
Query: 1095 LKDLNHVNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGL 1154
L + + +Y G K + +EY+ GGS L + G+ D+ I + +++L+GL
Sbjct: 84 LSQCDSQYVTKYFGSFLKGSKLWIIMEYLGGGSALDLTKS-GKLDESHIAVILREILKGL 142
Query: 1155 AYLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMV 1214
YLHS+ +HRD+KA N+L+ G K++DFG++ + +T G+ FWMAPE++
Sbjct: 143 EYLHSERKIHRDIKAANVLVSEHGDVKVADFGVAGQLTETVKKR-ITFVGSPFWMAPELI 201
Query: 1215 DTAHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSP 1274
+ Y K DIWSLG +E+ G+ P S+ + +F I K PP+ ++ S
Sbjct: 202 KQS-SYDYKADIWSLGITAIELANGEPPHSDLHPMRVLFLI--PKNPPPVLQGSQ--WSK 256
Query: 1275 AGQSFLDQCFEIDPEMRPTADSLVGHPFCK 1304
+ F++ C DPE RP+A +L+ H F K
Sbjct: 257 PFKEFVEMCLNKDPENRPSASTLLKHQFIK 286
>7300149 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 569
Score = 151 bits (381), Expect = 8e-36
Identities = 93/267 (34%), Positives = 152/267 (56%), Gaps = 19/267 (7%)
Query: 1044 IGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHVNI 1103
+GKG+ G V++A ++ +AVK + + SS+D + +E+ LKD NH N+
Sbjct: 299 VGKGASGIVFIAADLQNESQVAVKTIDMKNQSSKD--------LILTEIRVLKDFNHKNL 350
Query: 1104 VQYLG---FEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHSK 1160
V +L E ++ ++ + +EY+ GG + ++ + Q I + ++ L +++LH+K
Sbjct: 351 VNFLDAYLLEPEDQLW-VVMEYMDGGPLTDVVTETVMKERQ-IACVCRETLYAISFLHAK 408
Query: 1161 GILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVDTAHGY 1220
GI+HRD+K+DN+LL DG K++DFG +N TM GT +WMAPE+V T Y
Sbjct: 409 GIIHRDIKSDNVLLGMDGSVKVTDFGFC--ANIEGDEKRQTMVGTPYWMAPEVV-TRKKY 465
Query: 1221 SAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQSFL 1280
KVDIWS+G + +EM G+ P+ + A++ I + P I + D +SP Q FL
Sbjct: 466 GKKVDIWSIGIMAIEMIEGQPPYLYETPLRALYLIA-ANGRPDI--KSWDKLSPNLQDFL 522
Query: 1281 DQCFEIDPEMRPTADSLVGHPFCKTSS 1307
D+C +++ + R TAD L+ HPF S
Sbjct: 523 DRCLQVEVDRRATADELLSHPFLNDCS 549
>7302511 [T] KOG0576 Mitogen-activated protein kinase kinase kinase kinase
(MAP4K) germinal center kinase family
Length = 1218
Score = 149 bits (375), Expect = 4e-35
Identities = 91/299 (30%), Positives = 155/299 (51%), Gaps = 17/299 (5%)
Query: 1027 RNSRGEYKEFAWIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVE 1086
RN + EY+ + IG G++G VY A + + E+ A+K + + S D ++
Sbjct: 20 RNPQDEYELI-----QKIGSGTYGDVYKAKRIQSNELAAIKVIKLEP--SDD------IQ 66
Query: 1087 ALKSEVSTLKDLNHVNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHL 1146
++ E+ ++D H NI+ Y G + + +E+ GGS+ + ++ G + I ++
Sbjct: 67 IIQQEIIMMRDCRHPNIIAYYGSYLRRDKLWICMEFCGGGSLQDIYQVTGPLTEVQIAYM 126
Query: 1147 TKQVLEGLAYLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTV 1206
++ L+GL YLHS G +HRD+K N+LL G K++DFG+S + N + GT
Sbjct: 127 CRETLKGLEYLHSMGKMHRDIKGANILLTEYGDVKLADFGVSAQITATI-NKRKSFIGTP 185
Query: 1207 FWMAPEM--VDTAHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPI 1264
+WMAPE+ V+ GY+ DIW+ G +E+ + P + + A+F + KS PP
Sbjct: 186 YWMAPEVAAVERKGGYNQLCDIWACGITAIELAELQPPMFDLHPMRALFLMSKSGFKPPT 245
Query: 1265 PDDTKDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPFCKTSSSFDFPKTKLAQFIKSN 1323
++ KD SP +F+ +P+ RPTA+ L+ HPF + S K L ++ N
Sbjct: 246 LNN-KDKWSPTFHNFIKTALTKNPKKRPTAERLLQHPFVQCEMSLRVAKELLQKYQSPN 303
>CE27670 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 572
Score = 147 bits (372), Expect = 8e-35
Identities = 107/350 (30%), Positives = 180/350 (50%), Gaps = 27/350 (7%)
Query: 960 GESSQFLTPVKSLKPPKRTKTIRIIAQEASEA----RKNEVSQKLQRKNTKMWGTKVVEI 1015
GE+ + P P RT +I +E E K + + + + K T +
Sbjct: 220 GETPADIVPPAIPDRPARTLSIYTKPKEEEEKIPDLSKGQFGVQARGQKAKKKMTDAEVL 279
Query: 1016 TDKRTI-SINKSRNSRGEYKEFAWIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEF 1074
T RTI SI N +Y+ K + IG G+ G+VY A+ ++T +A+KQ+ + +
Sbjct: 280 TKLRTIVSIG---NPDRKYR-----KVDKIGSGASGSVYTAIEISTEAEVAIKQMNLKDQ 331
Query: 1075 SSQDESAISMVEALKSEVSTLKDLNHVNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRM 1134
+ E + +E+ +++ H NIV YL + +EY+AGGS+ ++
Sbjct: 332 PKK--------ELIINEILVMRENKHANIVNYLDSYLVCDELWVVMEYLAGGSLTDVVTE 383
Query: 1135 YGRFDDQLIRHLTKQVLEGLAYLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNI 1194
+ +D +I + ++VL+ L +LHS+ ++HRD+K+DN+LL DG K++DFG + +
Sbjct: 384 C-QMEDGIIAAVCREVLQALEFLHSRHVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSP- 441
Query: 1195 YSNSDMTMRGTVFWMAPEMVDTAHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQ 1254
TM GT +WMAPE+V T Y KVD+WSLG + +EM G+ P+ N + A++
Sbjct: 442 EQRKRTTMVGTPYWMAPEVV-TRKQYGPKVDVWSLGIMAIEMVEGEPPYLNENPLRAIYL 500
Query: 1255 IGKSKTAPPIPDDTKDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPFCK 1304
I + P P +D ++ + F+D E+ E R +A L+ HPF +
Sbjct: 501 IA-TNGKPDFPG--RDSMTLLFKDFVDSALEVQVENRWSASQLLTHPFLR 547
>Hs15451902 [T] KOG0576 Mitogen-activated protein kinase kinase kinase kinase
(MAP4K) germinal center kinase family
Length = 894
Score = 147 bits (371), Expect = 1e-34
Identities = 86/261 (32%), Positives = 144/261 (54%), Gaps = 12/261 (4%)
Query: 1044 IGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHVNI 1103
IG G++G VY A NV TGE+ A+K + + ++ A+ ++ E+ +KD H NI
Sbjct: 22 IGSGTYGDVYKARNVNTGELAAIKVI---KLEPGEDFAV-----VQQEIIMMKDCKHPNI 73
Query: 1104 VQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHSKGIL 1163
V Y G + + +E+ GGS+ + + G + I +++++ L+GL YLHSKG +
Sbjct: 74 VAYFGSYLRRDKLWICMEFCGGGSLQDIYHVTGPLSELQIAYVSRETLQGLYYLHSKGKM 133
Query: 1164 HRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEM--VDTAHGYS 1221
HRD+K N+LL ++G K++DFG+S + + + GT +WMAPE+ V+ GY+
Sbjct: 134 HRDIKGANILLTDNGHVKLADFGVSAQITATIAKR-KSFIGTPYWMAPEVAAVERKGGYN 192
Query: 1222 AKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQSFLD 1281
D+W++G +E+ + P + + A+F + KS PP D K S + F+
Sbjct: 193 QLCDLWAVGITAIELAELQPPMFDLHPMRALFLMTKSNFQPPKLKD-KMKWSNSFHHFVK 251
Query: 1282 QCFEIDPEMRPTADSLVGHPF 1302
+P+ RPTA+ L+ HPF
Sbjct: 252 MALTKNPKKRPTAEKLLQHPF 272
>SPAC1F5.09c [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 589
Score = 147 bits (370), Expect = 1e-34
Identities = 97/289 (33%), Positives = 164/289 (56%), Gaps = 11/289 (3%)
Query: 1015 ITDKRTISINKSRNSRGEYKEFAWIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEF 1074
+TD++ +++ K + + E+ +K ++ G+G+ G+VYLA V G+ L +
Sbjct: 287 MTDRQALAMLKDSVTSHDPVEYFNVKHKL-GQGASGSVYLA-KVVGGKQLGIFDSVA--I 342
Query: 1075 SSQDESAISMVEALKSEVSTLKDLNHVNIVQYL-GFEEKNGIYSLFLEYVAGGSVGSLIR 1133
S D + E + +E++ +++ H NIV YL F + + +EY+ GS+ +I
Sbjct: 343 KSIDLQCQTRKELILNEITVMRESIHPNIVTYLDSFLVRERHLWVVMEYMNAGSLTDIIE 402
Query: 1134 MYGRFDDQLIRHLTKQVLEGLAYLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNN 1193
+ Q+ R + + +G+ +LH++ I+HRD+K+DN+LLDN G KI+DFG + +N
Sbjct: 403 KSKLTEAQIAR-ICLETCKGIQHLHARNIIHRDIKSDNVLLDNSGNIKITDFGFCARLSN 461
Query: 1194 IYSNSDMTMRGTVFWMAPEMVDTAHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMF 1253
+N +TM GT +WMAPE+V + Y KVDIWSLG +++EM + P+ + + A++
Sbjct: 462 -RTNKRVTMVGTPYWMAPEVV-KQNEYGTKVDIWSLGIMIIEMIENEPPYLREDPIRALY 519
Query: 1254 QIGKSKTAPPIPDDTKDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPF 1302
I K+ T P + +LVS +SFL+ C ID R TA L+ H F
Sbjct: 520 LIAKNGT-PTL--KKPNLVSKNLKSFLNSCLTIDTIFRATAAELLTHSF 565
>HsM5454174 [T] KOG0201 Serine/threonine protein kinase
Length = 426
Score = 147 bits (370), Expect = 1e-34
Identities = 92/277 (33%), Positives = 154/277 (55%), Gaps = 16/277 (5%)
Query: 1026 SRNSRGEYKEFAWIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMV 1085
+++SR + +E + K + IGKGSFG VY ++ T E++A+K + + E ++DE +
Sbjct: 9 NQHSRVDPEEL-FTKLDRIGKGSFGEVYKGIDNHTKEVVAIKIIDLEE--AEDE-----I 60
Query: 1086 EALKSEVSTLKDLNHVNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRH 1145
E ++ E++ L + I +Y G K+ + +EY+ GGS L++ G ++ I
Sbjct: 61 EDIQQEITVLSQCDSPYITRYFGSYLKSTKLWIIMEYLGGGSALDLLKP-GPLEETYIAT 119
Query: 1146 LTKQVLEGLAYLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGT 1205
+ +++L+GL YLHS+ +HRD+KA N+LL G K++DFG++ + + + T GT
Sbjct: 120 ILREILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRN-TFVGT 178
Query: 1206 VFWMAPEMVDTAHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIP 1265
FWMAPE++ + Y K DIWSLG +E+ G+ P S+ + +F I K+ P
Sbjct: 179 PFWMAPEVIKQS-AYDFKADIWSLGITAIELAKGEPPNSDLHPMRVLFLIPKNS-----P 232
Query: 1266 DDTKDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPF 1302
+ S + F++ C DP RPTA L+ H F
Sbjct: 233 PTLEGQHSKPFKEFVEACLNKDPRFRPTAKELLKHKF 269
>Hs21361358 [T] KOG0201 Serine/threonine protein kinase
Length = 426
Score = 147 bits (370), Expect = 1e-34
Identities = 92/277 (33%), Positives = 154/277 (55%), Gaps = 16/277 (5%)
Query: 1026 SRNSRGEYKEFAWIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMV 1085
+++SR + +E + K + IGKGSFG VY ++ T E++A+K + + E ++DE +
Sbjct: 9 NQHSRVDPEEL-FTKLDRIGKGSFGEVYKGIDNHTKEVVAIKIIDLEE--AEDE-----I 60
Query: 1086 EALKSEVSTLKDLNHVNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRH 1145
E ++ E++ L + I +Y G K+ + +EY+ GGS L++ G ++ I
Sbjct: 61 EDIQQEITVLSQCDSPYITRYFGSYLKSTKLWIIMEYLGGGSALDLLKP-GPLEETYIAT 119
Query: 1146 LTKQVLEGLAYLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGT 1205
+ +++L+GL YLHS+ +HRD+KA N+LL G K++DFG++ + + + T GT
Sbjct: 120 ILREILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRN-TFVGT 178
Query: 1206 VFWMAPEMVDTAHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIP 1265
FWMAPE++ + Y K DIWSLG +E+ G+ P S+ + +F I K+ P
Sbjct: 179 PFWMAPEVIKQS-AYDFKADIWSLGITAIELAKGEPPNSDLHPMRVLFLIPKNS-----P 232
Query: 1266 DDTKDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPF 1302
+ S + F++ C DP RPTA L+ H F
Sbjct: 233 PTLEGQHSKPFKEFVEACLNKDPRFRPTAKELLKHKF 269
>At2g32510 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 372
Score = 147 bits (370), Expect = 1e-34
Identities = 90/283 (31%), Positives = 148/283 (51%), Gaps = 29/283 (10%)
Query: 1038 WIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKD 1097
W +G I+G+GS VY A + E+LAVK S + E L+ E L
Sbjct: 3 WTRGRILGRGSTATVYAAAGHNSDEILAVKS-----------SEVHRSEFLQREAKILSS 51
Query: 1098 LNHVNIVQYLGFE---EKNGI--YSLFLEYVAGGSV-GSLIRMYGRFDDQLIRHLTKQVL 1151
L+ ++ Y G E E NG+ Y+L +EY G++ + + GR D+ + T+ +L
Sbjct: 52 LSSPYVIGYRGSETKRESNGVVMYNLLMEYAPYGTLTDAAAKDGGRVDETRVVKYTRDIL 111
Query: 1152 EGLAYLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAP 1211
+GL Y+HSKGI+H D+K N+++ G KI+DFG +++ + ++ + M GT +MAP
Sbjct: 112 KGLEYIHSKGIVHCDVKGSNVVISEKGEAKIADFGCAKRVDPVFESPVM---GTPAFMAP 168
Query: 1212 EMVDTAHGYSAKVDIWSLGCVVLEMFAGKRPW----SNFEVVAAMFQIGKSKTAPPIPDD 1267
E V + DIW++GC ++EM G PW S + V+ ++++G S P +P
Sbjct: 169 E-VARGEKQGKESDIWAVGCTMIEMVTGSPPWTKADSREDPVSVLYRVGYSSETPELP-- 225
Query: 1268 TKDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPFCKTSSSFD 1310
L++ + FL++C + + R TA L+ HPF T +
Sbjct: 226 --CLLAEEAKDFLEKCLKREANERWTATQLLNHPFLTTKPDIE 266
>YHL007c [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 939
Score = 146 bits (368), Expect = 2e-34
Identities = 108/392 (27%), Positives = 199/392 (50%), Gaps = 27/392 (6%)
Query: 944 SLKTKSEQQPAFLSSRGESSQFL----TPVKSLKPPKRTKTIRIIAQEASEARKNEVSQK 999
+LK + + P ++ ++S + TP + + PK + + A+ +S++
Sbjct: 528 TLKKEEQPLPPIPPTKSKTSPIISTAHTPQQVAQSPKAPAQETVTTPTSKPAQARSLSKE 587
Query: 1000 LQRKNTKMWGTKVVEITDKRTISINKSRNSRGEYKEFAWIKGEIIGKGSFGAVYLALNVT 1059
L K + + ++ K +N+ + ++A + IG+G+ G VY A +
Sbjct: 588 LNEKKREERERRKKQLYAK----LNEICSDGDPSTKYANLVK--IGQGASGGVYTAYEIG 641
Query: 1060 TGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHVNIVQYLGFEEKNGIYSLF 1119
T +A+KQ+ + + + E + +E+ +K H NIV ++ G +
Sbjct: 642 TNVSVAIKQMNLEKQPKK--------ELIINEILVMKGSKHPNIVNFIDSYVLKGDLWVI 693
Query: 1120 LEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHSKGILHRDMKADNLLLDNDGV 1179
+EY+ GGS+ ++ + Q I + ++ L GL +LHSKG+LHRD+K+DN+LL +G
Sbjct: 694 MEYMEGGSLTDVVTHCILTEGQ-IGAVCRETLSGLEFLHSKGVLHRDIKSDNILLSMEGD 752
Query: 1180 CKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVDTAHGYSAKVDIWSLGCVVLEMFAG 1239
K++DFG + N + + TM GT +WMAPE+V Y KVDIWSLG +++EM G
Sbjct: 753 IKLTDFGFCAQINEL-NLKRTTMVGTPYWMAPEVVSRKE-YGPKVDIWSLGIMIIEMIEG 810
Query: 1240 KRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQSFLDQCFEIDPEMRPTADSLVG 1299
+ P+ N + A++ I + T P + + + +S + + FLD C ++PE R +A L+
Sbjct: 811 EPPYLNETPLRALYLIATNGT-PKLKE--PENLSSSLKKFLDWCLCVEPEDRASATELLH 867
Query: 1300 HPF---CKTSSSFDFPKTKLAQFIKSNDKLNS 1328
+ ++S P KLA+ K + +++
Sbjct: 868 DEYITEIAEANSSLAPLVKLARLKKVAENMDA 899
>CE27965 [T] KOG0574 STE20-like serine/threonine kinase MST
Length = 525
Score = 146 bits (368), Expect = 2e-34
Identities = 89/268 (33%), Positives = 144/268 (53%), Gaps = 16/268 (5%)
Query: 1044 IGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHVNI 1103
+G+GS+G+V+ A++ +G +LA+K+V V + IS+++ KS+ +
Sbjct: 69 LGEGSYGSVHKAIHRESGHVLAIKKVPVDTDLQEIIKEISIMQQCKSKY----------V 118
Query: 1104 VQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGR-FDDQLIRHLTKQVLEGLAYLHSKGI 1162
V+Y G K+ + +EY GS+ ++R + +Q I + + L+GL YLH
Sbjct: 119 VKYYGSYFKHSDLWIVMEYCGAGSISDIMRARRKPLSEQEISAVLRDTLKGLQYLHDLKK 178
Query: 1163 LHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVDTAHGYSA 1222
+HRD+KA N+LL+ DG+ K++DFG++ + + + + T+ GT FWMAPE+++ GY
Sbjct: 179 IHRDIKAGNILLNTDGIAKLADFGVAGQLTDTMAKRN-TVIGTPFWMAPEVIEEI-GYDT 236
Query: 1223 KVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQSFLDQ 1282
K DIWSLG +EM G+ P+S+ + A+F I T PP + S F+
Sbjct: 237 KADIWSLGITAIEMAEGRPPYSDIHPMRAIFMI---PTKPPPTFKKPEEWSSEFNDFIRS 293
Query: 1283 CFEIDPEMRPTADSLVGHPFCKTSSSFD 1310
C PE R TA L H F K + D
Sbjct: 294 CLIKKPEERKTALRLCEHTFIKNAPGCD 321
>CE27726 [T] KOG0574 STE20-like serine/threonine kinase MST
Length = 640
Score = 146 bits (368), Expect = 2e-34
Identities = 89/268 (33%), Positives = 144/268 (53%), Gaps = 16/268 (5%)
Query: 1044 IGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHVNI 1103
+G+GS+G+V+ A++ +G +LA+K+V V + IS+++ KS+ +
Sbjct: 41 LGEGSYGSVHKAIHRESGHVLAIKKVPVDTDLQEIIKEISIMQQCKSKY----------V 90
Query: 1104 VQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGR-FDDQLIRHLTKQVLEGLAYLHSKGI 1162
V+Y G K+ + +EY GS+ ++R + +Q I + + L+GL YLH
Sbjct: 91 VKYYGSYFKHSDLWIVMEYCGAGSISDIMRARRKPLSEQEISAVLRDTLKGLQYLHDLKK 150
Query: 1163 LHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVDTAHGYSA 1222
+HRD+KA N+LL+ DG+ K++DFG++ + + + + T+ GT FWMAPE+++ GY
Sbjct: 151 IHRDIKAGNILLNTDGIAKLADFGVAGQLTDTMAKRN-TVIGTPFWMAPEVIEEI-GYDT 208
Query: 1223 KVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQSFLDQ 1282
K DIWSLG +EM G+ P+S+ + A+F I T PP + S F+
Sbjct: 209 KADIWSLGITAIEMAEGRPPYSDIHPMRAIFMI---PTKPPPTFKKPEEWSSEFNDFIRS 265
Query: 1283 CFEIDPEMRPTADSLVGHPFCKTSSSFD 1310
C PE R TA L H F K + D
Sbjct: 266 CLIKKPEERKTALRLCEHTFIKNAPGCD 293
>CE27082 [T] KOG0574 STE20-like serine/threonine kinase MST
Length = 421
Score = 146 bits (368), Expect = 2e-34
Identities = 89/268 (33%), Positives = 144/268 (53%), Gaps = 16/268 (5%)
Query: 1044 IGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHVNI 1103
+G+GS+G+V+ A++ +G +LA+K+V V + IS+++ KS+ +
Sbjct: 41 LGEGSYGSVHKAIHRESGHVLAIKKVPVDTDLQEIIKEISIMQQCKSKY----------V 90
Query: 1104 VQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGR-FDDQLIRHLTKQVLEGLAYLHSKGI 1162
V+Y G K+ + +EY GS+ ++R + +Q I + + L+GL YLH
Sbjct: 91 VKYYGSYFKHSDLWIVMEYCGAGSISDIMRARRKPLSEQEISAVLRDTLKGLQYLHDLKK 150
Query: 1163 LHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVDTAHGYSA 1222
+HRD+KA N+LL+ DG+ K++DFG++ + + + + T+ GT FWMAPE+++ GY
Sbjct: 151 IHRDIKAGNILLNTDGIAKLADFGVAGQLTDTMAKRN-TVIGTPFWMAPEVIEEI-GYDT 208
Query: 1223 KVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQSFLDQ 1282
K DIWSLG +EM G+ P+S+ + A+F I T PP + S F+
Sbjct: 209 KADIWSLGITAIEMAEGRPPYSDIHPMRAIFMI---PTKPPPTFKKPEEWSSEFNDFIRS 265
Query: 1283 CFEIDPEMRPTADSLVGHPFCKTSSSFD 1310
C PE R TA L H F K + D
Sbjct: 266 CLIKKPEERKTALRLCEHTFIKNAPGCD 293
>CE07064 [T] KOG0574 STE20-like serine/threonine kinase MST
Length = 523
Score = 146 bits (368), Expect = 2e-34
Identities = 89/268 (33%), Positives = 144/268 (53%), Gaps = 16/268 (5%)
Query: 1044 IGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHVNI 1103
+G+GS+G+V+ A++ +G +LA+K+V V + IS+++ KS+ +
Sbjct: 69 LGEGSYGSVHKAIHRESGHVLAIKKVPVDTDLQEIIKEISIMQQCKSKY----------V 118
Query: 1104 VQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGR-FDDQLIRHLTKQVLEGLAYLHSKGI 1162
V+Y G K+ + +EY GS+ ++R + +Q I + + L+GL YLH
Sbjct: 119 VKYYGSYFKHSDLWIVMEYCGAGSISDIMRARRKPLSEQEISAVLRDTLKGLQYLHDLKK 178
Query: 1163 LHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVDTAHGYSA 1222
+HRD+KA N+LL+ DG+ K++DFG++ + + + + T+ GT FWMAPE+++ GY
Sbjct: 179 IHRDIKAGNILLNTDGIAKLADFGVAGQLTDTMAKRN-TVIGTPFWMAPEVIEEI-GYDT 236
Query: 1223 KVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQSFLDQ 1282
K DIWSLG +EM G+ P+S+ + A+F I T PP + S F+
Sbjct: 237 KADIWSLGITAIEMAEGRPPYSDIHPMRAIFMI---PTKPPPTFKKPEEWSSEFNDFIRS 293
Query: 1283 CFEIDPEMRPTADSLVGHPFCKTSSSFD 1310
C PE R TA L H F K + D
Sbjct: 294 CLIKKPEERKTALRLCEHTFIKNAPGCD 321
>SPAC2F3.15 [D] KOG0600 Cdc2-related protein kinase
Length = 593
Score = 145 bits (366), Expect = 4e-34
Identities = 96/302 (31%), Positives = 158/302 (51%), Gaps = 35/302 (11%)
Query: 1033 YKEFAWIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEV 1092
Y + A+ K + IG+G++G VY A+N TG+++A+K++ + + +D I+ V EV
Sbjct: 272 YPKPAYEKIDQIGEGTYGKVYKAINTVTGDLVALKRIRLEQ--EKDGFPITTVR----EV 325
Query: 1093 STLKDLNHVNIVQYLGFE-EKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVL 1151
L+ L H NIV+ L EK+ +Y +F EY+ G L+ F I+HL+KQ+
Sbjct: 326 KILQRLRHKNIVRLLEIMVEKSSVYMVF-EYMDHDLTGVLLNSQLHFTPGNIKHLSKQIF 384
Query: 1152 EGLAYLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAP 1211
E LAYLH +G+LHRD+K N+LL+N+G K +DFG++R + + S + T+++ P
Sbjct: 385 EALAYLHHRGVLHRDIKGSNILLNNNGDLKFADFGLARFNTSSKSANYTNRVITLWFRPP 444
Query: 1212 EMVDTAHGYSAKVDIWSLGCVVLEMFAGKRPW-------SNFEVVAAMFQIGKSKTAPPI 1264
E++ Y VDIWS GC+V+E+F GK P+ S EV+ M + P +
Sbjct: 445 ELLLGETAYDTAVDIWSAGCIVMELFTGK-PFFQGRDEISQLEVIYDMMGTPDVHSWPEV 503
Query: 1265 P-------------------DDTKDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPFCKT 1305
+ K+++SPA + ++P RP+A + H + +
Sbjct: 504 KNLPWYELLKPVEEKKSRFVETFKEILSPAAIDLCQKLLALNPFCRPSAHETLMHEYFTS 563
Query: 1306 SS 1307
S
Sbjct: 564 ES 565
>Hs20070158 [T] KOG0201 Serine/threonine protein kinase
Length = 443
Score = 145 bits (365), Expect = 5e-34
Identities = 90/277 (32%), Positives = 151/277 (54%), Gaps = 16/277 (5%)
Query: 1026 SRNSRGEYKEFAWIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMV 1085
S N + + +E + K E IGKGSFG V+ ++ T +++A+K + + E ++DE +
Sbjct: 25 STNLKADPEEL-FTKLEKIGKGSFGEVFKGIDNRTQKVVAIKIIDLEE--AEDE-----I 76
Query: 1086 EALKSEVSTLKDLNHVNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRH 1145
E ++ E++ L + + +Y G K+ + +EY+ GGS L+ G D+ I
Sbjct: 77 EDIQQEITVLSQCDSPYVTKYYGSYLKDTKLWIIMEYLGGGSALDLLEP-GPLDETQIAT 135
Query: 1146 LTKQVLEGLAYLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGT 1205
+ +++L+GL YLHS+ +HRD+KA N+LL G K++DFG++ + + + T GT
Sbjct: 136 ILREILKGLDYLHSEKKIHRDIKAANVLLSEHGEVKLADFGVAGQLTDTQIKRN-TFVGT 194
Query: 1206 VFWMAPEMVDTAHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIP 1265
FWMAPE++ + Y +K DIWSLG +E+ G+ P S + +F I K+ P
Sbjct: 195 PFWMAPEVIKQS-AYDSKADIWSLGITAIELARGEPPHSELHPMKVLFLIPKNN-----P 248
Query: 1266 DDTKDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPF 1302
+ S + F++ C +P RPTA L+ H F
Sbjct: 249 PTLEGNYSKPLKEFVEACLNKEPSFRPTAKELLKHKF 285
>SPBC1604.14c [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 658
Score = 144 bits (363), Expect = 9e-34
Identities = 95/283 (33%), Positives = 156/283 (54%), Gaps = 26/283 (9%)
Query: 1044 IGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHVNI 1103
IG+G+ G VY A V T +A+K++ + + + E + +E+ +K +H NI
Sbjct: 392 IGQGASGDVYSARQVGTNLSVAIKKMNINQQPKK--------EFIVNEILVMKSHHHKNI 443
Query: 1104 VQYLG-FEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHSKGI 1162
V ++ F K+ ++ + +EY+ GGS+ ++ + Q I + K+ LEGL +LH GI
Sbjct: 444 VNFIDTFFYKSELW-MVMEYMRGGSLTEVVTNNTLSEGQ-IAAICKETLEGLQHLHENGI 501
Query: 1163 LHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVDTAHGYSA 1222
+HRD+K+DN+LL G K++DFG + ++ + TM GT +WMAPE+V T Y
Sbjct: 502 VHRDIKSDNILLSLQGDIKLTDFGFCAQIDSNMTKR-TTMVGTPYWMAPEVV-TRKEYGF 559
Query: 1223 KVDIWSLGCVVLEMFAGKRPWSNFEVVAAMF---QIGKSKTAPPIPDDTKDLVSPAGQSF 1279
KVD+WSLG + +EM G+ P+ N + A++ IG K + P +L+S F
Sbjct: 560 KVDVWSLGIMAIEMVEGEPPYLNENPLRALYLIATIGTPKISRP------ELLSSVFHDF 613
Query: 1280 LDQCFEIDPEMRPTADSLVGHPFCKTSSSFDFPKTKLAQFIKS 1322
L + ++P+ RP++ L+ HPF K + P + L IKS
Sbjct: 614 LSKSLTVNPKQRPSSGELLRHPFLKQA----VPVSSLIPLIKS 652
>Hs14589909 [T] KOG0576 Mitogen-activated protein kinase kinase kinase kinase
(MAP4K) germinal center kinase family
Length = 846
Score = 144 bits (362), Expect = 1e-33
Identities = 87/262 (33%), Positives = 143/262 (54%), Gaps = 14/262 (5%)
Query: 1044 IGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHVNI 1103
+G G++G VY A NV TGE+ AVK + + D+ ++ ++ E+ +K+ H NI
Sbjct: 26 VGSGTYGDVYKARNVHTGELAAVKII---KLEPGDDFSL-----IQQEIFMVKECKHCNI 77
Query: 1104 VQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHSKGIL 1163
V Y G + +EY GGS+ + + G + I ++ ++ L+GLAYLH+KG +
Sbjct: 78 VAYFGSYLSREKLWICMEYCGGGSLQDIYHVTGPLSELQIAYVCRETLQGLAYLHTKGKM 137
Query: 1164 HRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEM--VDTAHGYS 1221
HRD+K N+LL + G K++DFG++ K + + GT +WMAPE+ V+ GY+
Sbjct: 138 HRDIKGANILLTDHGDVKLADFGVAAKITATIAKR-KSFIGTPYWMAPEVAAVEKNGGYN 196
Query: 1222 AKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPP-IPDDTKDLVSPAGQSFL 1280
DIW++G +E+ + P + + A+F + KS PP + D TK S +F+
Sbjct: 197 QLCDIWAVGITAIELGELQPPMFDLHPMRALFLMSKSNFQPPKLKDKTK--WSSTFHNFV 254
Query: 1281 DQCFEIDPEMRPTADSLVGHPF 1302
+P+ RPTA+ L+ H F
Sbjct: 255 KIALTKNPKKRPTAERLLTHTF 276
>SPCC18B5.11c [D] KOG0615 Serine/threonine protein kinase Chk2 and related proteins
Length = 460
Score = 143 bits (361), Expect = 2e-33
Identities = 93/293 (31%), Positives = 158/293 (53%), Gaps = 13/293 (4%)
Query: 1044 IGKGSFGAVYLALNVTTGEMLAVKQVTVPEF--SSQDESAISMVEALKSEVSTLKDLNHV 1101
+G G+F V LA+ V +G+ A+K + + +S ++ A M + E+ LK L+H
Sbjct: 173 LGSGTFAVVKLAVEVNSGKWYAIKIINKRKILLTSSEKRATEMFQR---EIDILKSLHHP 229
Query: 1102 NIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHSKG 1161
+VQ E + + +EYV GG + + G D+Q + L KQ+LE L +LH +G
Sbjct: 230 GVVQCHEIFENDDELFIVMEYVEGGDLMDFLIANGSIDEQDCKPLLKQLLETLLHLHKQG 289
Query: 1162 ILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVDTAH--- 1218
+ HRD+K +N+L+ ND KISDFG+++ + + + T GT+ ++APE++ + +
Sbjct: 290 VTHRDIKPENILITNDFHLKISDFGLAKVIHGTGTFLE-TFCGTMGYLAPEVLKSKNVNL 348
Query: 1219 --GYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAG 1276
GY KVDIWSLGCV+ M P+++ + I SK A PI ++ +S G
Sbjct: 349 DGGYDDKVDIWSLGCVLYVMLTASIPFASSSQAKCIELI--SKGAYPIEPLLENEISEEG 406
Query: 1277 QSFLDQCFEIDPEMRPTADSLVGHPFCKTSSSFDFPKTKLAQFIKSNDKLNSS 1329
+++ EI+PE R + + HP+ T S+ + + ++ ++LNSS
Sbjct: 407 IDLINRMLEINPEKRISESEALQHPWFYTVSTHEHRTPPSSSEHEATEQLNSS 459
>Hs14771959 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 719
Score = 142 bits (359), Expect = 3e-33
Identities = 91/264 (34%), Positives = 147/264 (55%), Gaps = 20/264 (7%)
Query: 1044 IGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHVNI 1103
IG+GS G V +A TG+ +AVK++ + + + E L +EV ++D +H N+
Sbjct: 455 IGEGSTGIVCIATEKHTGKQVAVKKMDLRKQQRR--------ELLFNEVVIMRDYHHDNV 506
Query: 1104 VQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHSKGIL 1163
V + +E++ GG++ ++ + R +++ I + VL L+YLH++G++
Sbjct: 507 VDMYSSYLVGDELWVVMEFLEGGALTDIVT-HTRMNEEQIATVCLSVLRALSYLHNQGVI 565
Query: 1164 HRDMKADNLLLDNDGVCKISDFGI-SRKSNNIYSNSDMTMRGTVFWMAPEMVDTAHGYSA 1222
HRD+K+D++LL +DG K+SDFG ++ S + + GT +WMAPE++ Y
Sbjct: 566 HRDIKSDSILLTSDGRIKLSDFGFCAQVSKEVPKRKSLV--GTPYWMAPEVISRL-PYGT 622
Query: 1223 KVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDL--VSPAGQSFL 1280
+VDIWSLG +V+EM G+ P+ N + AM +I S +P KDL VS + FL
Sbjct: 623 EVDIWSLGIMVIEMIDGEPPYFNEPPLQAMRRIRDS-----LPPRVKDLHKVSSVLRGFL 677
Query: 1281 DQCFEIDPEMRPTADSLVGHPFCK 1304
D +P R TA L+GHPF K
Sbjct: 678 DLMLVREPSQRATAQELLGHPFLK 701
>At5g14720 [T] KOG0582 Ste20-like serine/threonine protein kinase
Length = 561
Score = 142 bits (358), Expect = 4e-33
Identities = 88/276 (31%), Positives = 148/276 (52%), Gaps = 16/276 (5%)
Query: 1042 EIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHV 1101
E IG G V+ AL + ++A+K + + + ++ ++ ++ EV T+ +NH
Sbjct: 20 EEIGDGVSATVHRALCIPLNVVVAIKVLDLEKCNND-------LDGIRREVQTMSLINHP 72
Query: 1102 NIVQ-YLGFEEKNGIYSLFLEYVAGGSVGSLIRMY--GRFDDQLIRHLTKQVLEGLAYLH 1158
N++Q + F + ++ + + Y+AGGS +I+ F++ +I L ++ L+ L YLH
Sbjct: 73 NVLQAHCSFTTGHQLW-VVMPYMAGGSCLHIIKSSYPDGFEEPVIATLLRETLKALVYLH 131
Query: 1159 SKGILHRDMKADNLLLDNDGVCKISDFGIS--RKSNNIYSNSDMTMRGTVFWMAPEMVDT 1216
+ G +HRD+KA N+LLD++G K++DFG+S S T GT WMAPE++
Sbjct: 132 AHGHIHRDVKAGNILLDSNGAVKLADFGVSACMFDTGDRQRSRNTFVGTPCWMAPEVMQQ 191
Query: 1217 AHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKD-LVSPA 1275
HGY K D+WS G LE+ G P+S + + + + APP D +D S A
Sbjct: 192 LHGYDFKADVWSFGITALELAHGHAPFSKYPPMKVLLM--TLQNAPPGLDYERDKRFSKA 249
Query: 1276 GQSFLDQCFEIDPEMRPTADSLVGHPFCKTSSSFDF 1311
+ + C DP+ RPT++ L+ HPF K + D+
Sbjct: 250 FKEMVGTCLVKDPKKRPTSEKLLKHPFFKHARPADY 285
>At3g50310 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 342
Score = 142 bits (358), Expect = 4e-33
Identities = 99/301 (32%), Positives = 159/301 (51%), Gaps = 25/301 (8%)
Query: 1038 WIKGEIIGKGSFGAVYLALNV-TTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLK 1096
W++GE IG G+F V A +G+ A+ V S D + + KS + +L
Sbjct: 3 WVRGETIGFGTFSTVSTATKSRNSGDFPALIAV-----KSTDAYGAASLSNEKSVLDSLG 57
Query: 1097 DLNHVNIVQYLGFEE--KNG--IYSLFLEYVAGGSVGSLIRMYGR--FDDQLIRHLTKQV 1150
D I++ G + +NG +++L LEY + GS+ S ++ G + +R T V
Sbjct: 58 DCPE--IIRCYGEDSTVENGEEMHNLLLEYASRGSLASYMKKLGGEGLPESTVRRHTGSV 115
Query: 1151 LEGLAYLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYS--NSDMTMRGTVFW 1208
L GL ++H+KG H D+K N+LL NDG KI+DFG++ + + + + +RGT +
Sbjct: 116 LRGLRHIHAKGFAHCDIKLANILLFNDGSVKIADFGLAMRVDGDLTALRKSVEIRGTPLY 175
Query: 1209 MAPEMVDTAHGYSAKVDIWSLGCVVLEMFAGKRPWSNFE---VVAAMFQIGKSKTAPPIP 1265
MAPE V+ + Y + D+W+LGC V+EMF+GK WS E ++ + +IG P IP
Sbjct: 176 MAPECVND-NEYGSAADVWALGCAVVEMFSGKTAWSVKEGSHFMSLLIRIGVGDELPKIP 234
Query: 1266 DDTKDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPFCKTSSSFDFPKTKLAQFIKSNDK 1325
+++S G+ FL +CF DP R TA+ L+ H F D + + + +K DK
Sbjct: 235 ----EMLSEEGKDFLSKCFVKDPAKRWTAEMLLNHSFVTIDLEDDHRENFVVK-VKDEDK 289
Query: 1326 L 1326
+
Sbjct: 290 V 290
>Hs4826878 [T] KOG0582 Ste20-like serine/threonine protein kinase
Length = 527
Score = 141 bits (356), Expect = 6e-33
Identities = 97/296 (32%), Positives = 151/296 (50%), Gaps = 29/296 (9%)
Query: 1042 EIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHV 1101
E+IG G+ V A E +A+K++ + ++ SM E LK E+ + +H
Sbjct: 21 EVIGSGATAVVQAAYCAPKKEKVAIKRINL------EKCQTSMDELLK-EIQAMSQCHHP 73
Query: 1102 NIVQYL-GFEEKNGIYSLFLEYVAGGSVGSLIRMY--------GRFDDQLIRHLTKQVLE 1152
NIV Y F K+ ++ L ++ ++GGSV +I+ G D+ I + ++VLE
Sbjct: 74 NIVSYYTSFVVKDELW-LVMKLLSGGSVLDIIKHIVAKGEHKSGVLDESTIATILREVLE 132
Query: 1153 GLAYLHSKGILHRDMKADNLLLDNDGVCKISDFGIS---RKSNNIYSNS-DMTMRGTVFW 1208
GL YLH G +HRD+KA N+LL DG +I+DFG+S +I N T GT W
Sbjct: 133 GLEYLHKNGQIHRDVKAGNILLGEDGSVQIADFGVSAFLATGGDITRNKVRKTFVGTPCW 192
Query: 1209 MAPEMVDTAHGYSAKVDIWSLGCVVLEMFAGKRPWSNF---EVVAAMFQIGKSKTAPPIP 1265
MAPE+++ GY K DIWS G +E+ G P+ + +V+ Q +
Sbjct: 193 MAPEVMEQVRGYDFKADIWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPSLETGVQ 252
Query: 1266 DDTKDLVSPAGQSF---LDQCFEIDPEMRPTADSLVGHPFCKTSSSFDFPKTKLAQ 1318
D K+++ G+SF + C + DPE RPTA L+ H F + + + +F + K Q
Sbjct: 253 D--KEMLKKYGKSFRKMISLCLQKDPEKRPTAAELLRHKFFQKAKNKEFLQEKTLQ 306
>Hs9910476 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 681
Score = 141 bits (355), Expect = 8e-33
Identities = 91/264 (34%), Positives = 151/264 (56%), Gaps = 24/264 (9%)
Query: 1044 IGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHVNI 1103
IG+GS G V LA +G +AVK + + + + E L +EV ++D H N+
Sbjct: 413 IGEGSTGIVCLAREKHSGRQVAVKMMDLRKQQRR--------ELLFNEVVIMRDYQHFNV 464
Query: 1104 VQ----YLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHS 1159
V+ YL EE + +E++ GG++ ++ R +++ I + + VL+ LAYLH+
Sbjct: 465 VEMYKSYLVGEE----LWVLMEFLQGGALTDIVSQV-RLNEEQIATVCEAVLQALAYLHA 519
Query: 1160 KGILHRDMKADNLLLDNDGVCKISDFGI-SRKSNNIYSNSDMTMRGTVFWMAPEMVDTAH 1218
+G++HRD+K+D++LL DG K+SDFG ++ S ++ + GT +WMAPE++ +
Sbjct: 520 QGVIHRDIKSDSILLTLDGRVKLSDFGFCAQISKDVPKRKSLV--GTPYWMAPEVISRSL 577
Query: 1219 GYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQS 1278
Y+ +VDIWSLG +V+EM G+ P+ + V AM ++ + +PP VSP +
Sbjct: 578 -YATEVDIWSLGIMVIEMVDGEPPYFSDSPVQAMKRL---RDSPPPKLKNSHKVSPVLRD 633
Query: 1279 FLDQCFEIDPEMRPTADSLVGHPF 1302
FL++ DP+ R TA L+ HPF
Sbjct: 634 FLERMLVRDPQERATAQELLDHPF 657
>At4g29810 [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K)
Length = 363
Score = 140 bits (354), Expect = 1e-32
Identities = 100/316 (31%), Positives = 162/316 (50%), Gaps = 20/316 (6%)
Query: 1009 GTKVVEITDKRTISINKSRNSRGEYKEFAWIKGEIIGKGSFGAVYLALNVTTGEMLAVKQ 1068
G +++ + +S K + + + +K +IGKGS G V L + TG+ A+K
Sbjct: 43 GVRIISQLEPEVLSPIKPADDQLSLSDLDMVK--VIGKGSSGVVQLVQHKWTGQFFALKV 100
Query: 1069 VTVPEFSSQDESAISMVEALKSEVSTLKDLNHVNIV-QYLGFEEKNGIYSLFLEYVAGGS 1127
+ + + DE+ + +A+ E+ + N+V Y F + NG SL LEY+ GGS
Sbjct: 101 IQL----NIDEA---IRKAIAQELKINQSSQCPNLVTSYQSFYD-NGAISLILEYMDGGS 152
Query: 1128 VGSLIRMYGRFDDQLIRHLTKQVLEGLAYL-HSKGILHRDMKADNLLLDNDGVCKISDFG 1186
+ ++ D + + +QVL+GL YL H + I+HRD+K NLL+++ G KI+DFG
Sbjct: 153 LADFLKSVKAIPDSYLSAIFRQVLQGLIYLHHDRHIIHRDLKPSNLLINHRGEVKITDFG 212
Query: 1187 ISRKSNNIYSNSDMTMRGTVFWMAPEMVDTAHGYSAKVDIWSLGCVVLEMFAGKRPW--- 1243
+S N ++ T GT +M+PE + + Y K DIWSLG VVLE GK P+
Sbjct: 213 VSTVMTNTAGLAN-TFVGTYNYMSPERI-VGNKYGNKSDIWSLGLVVLECATGKFPYAPP 270
Query: 1244 SNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPFC 1303
+ E ++F++ ++ P P SP SF+ C + DP R +A L+ HPF
Sbjct: 271 NQEETWTSVFELMEAIVDQPPPALPSGNFSPELSSFISTCLQKDPNSRSSAKELMEHPFL 330
Query: 1304 KTSSSFDFPKTKLAQF 1319
+ +D+ LA +
Sbjct: 331 ---NKYDYSGINLASY 343
>Hs22035600 [T] KOG0576 Mitogen-activated protein kinase kinase kinase kinase
(MAP4K) germinal center kinase family
Length = 820
Score = 140 bits (353), Expect = 1e-32
Identities = 90/296 (30%), Positives = 152/296 (50%), Gaps = 19/296 (6%)
Query: 1044 IGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHVNI 1103
+G G++G VY A + T E+ AVK V + + +L+ E++ L++ H N+
Sbjct: 22 VGAGTYGDVYKARDTVTSELAAVKIVKLDPGDD--------ISSLQQEITILRECRHPNV 73
Query: 1104 VQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHSKGIL 1163
V Y+G +N + +E+ GGS+ + G +++ I ++ ++ L+GL +LHS+G +
Sbjct: 74 VAYIGSYLRNDRLWICMEFCGGGSLQEIYHATGPLEERQIAYVCREALKGLHHLHSQGKI 133
Query: 1164 HRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEM--VDTAHGYS 1221
HRD+K NLLL G K++DFG+S + + + GT +WMAPE+ V+ GY+
Sbjct: 134 HRDIKGANLLLTLQGDVKLADFGVSGELTASVAKR-RSFIGTPYWMAPEVAAVERKGGYN 192
Query: 1222 AKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQSFLD 1281
D+W+LG +E+ + P + + A+ + KS PP D K + FL
Sbjct: 193 ELCDVWALGITAIELGELQPPLFHLHPMRALMLMSKSSFQPPKLRD-KTRWTQNFHHFLK 251
Query: 1282 QCFEIDPEMRPTADSLVGHPFCKTSSSFDFPKTKLAQFIKSNDKLNSSRLRISSQE 1337
+P+ RPTA+ L+ HPF ++ P+ L Q + DK + L S E
Sbjct: 252 LALTKNPKKRPTAEKLLQHPF----TTQQLPRALLTQLL---DKASDPHLGTPSPE 300
>HsM4759010 [T] KOG0576 Mitogen-activated protein kinase kinase kinase kinase
(MAP4K) germinal center kinase family
Length = 819
Score = 139 bits (350), Expect = 3e-32
Identities = 90/296 (30%), Positives = 152/296 (50%), Gaps = 19/296 (6%)
Query: 1044 IGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHVNI 1103
+G G++G VY A + T E+ AVK V + + +L+ E++ L++ H N+
Sbjct: 21 VGAGTYGDVYKARDTVTSELAAVKIVKLDPGDD--------ISSLQQEITILRECRHPNV 72
Query: 1104 VQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHSKGIL 1163
V Y+G +N + +E+ GGS+ + G +++ I ++ ++ L+GL +LHS+G +
Sbjct: 73 VAYIGSYLRNDRLWICMEFCGGGSLQEIYHATGPLEERQIAYVCRERLKGLHHLHSQGKI 132
Query: 1164 HRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEM--VDTAHGYS 1221
HRD+K NLLL G K++DFG+S + + + GT +WMAPE+ V+ GY+
Sbjct: 133 HRDIKGANLLLTLQGDVKLADFGVSGELTASVAKR-RSFIGTPYWMAPEVAAVERKGGYN 191
Query: 1222 AKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQSFLD 1281
D+W+LG +E+ + P + + A+ + KS PP D K + FL
Sbjct: 192 ELCDVWALGITAIELGELQPPLFHLHPMRALMLMSKSSFQPPKLRD-KTRWTQNFHHFLK 250
Query: 1282 QCFEIDPEMRPTADSLVGHPFCKTSSSFDFPKTKLAQFIKSNDKLNSSRLRISSQE 1337
+P+ RPTA+ L+ HPF ++ P+ L Q + DK + L S E
Sbjct: 251 LALTKNPKKRPTAEKLLQHPF----TTQQLPRALLTQLL---DKASDPHLGTPSPE 299
>CE27573 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 1420
Score = 138 bits (347), Expect = 7e-32
Identities = 88/286 (30%), Positives = 142/286 (48%), Gaps = 26/286 (9%)
Query: 1036 FAWIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTL 1095
F W + I GSFG+V+ A+++ + ++A K + + + + A++SE++
Sbjct: 1123 FQWALLDHIASGSFGSVHRAMDIDSHRVIAAKVMRIQRENHK---------AIESEINIF 1173
Query: 1096 KDLNHVNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLA 1155
+ L H N+V+Y G + ++ +F+EY + G++ + +G+ D +++R T +L +
Sbjct: 1174 RQLIHENLVKYYGVQVEDSDVIIFMEYCSQGTLERIC--HGKMDLKMVRQYTNSLLRAVQ 1231
Query: 1156 YLHSKGILHRDMKADNLLLDNDGVCKISDFGISRK---SNNIYSNSDMTMRGTVFWMAPE 1212
YLHS I+HRD+K N+ LD V K+ DFG S + S+ +Y T GT +MAPE
Sbjct: 1232 YLHSHKIIHRDIKPANIFLDKCTVLKLGDFGCSSRLVESSTVYGEF-QTTAGTPQFMAPE 1290
Query: 1213 M---------VDTAHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPP 1263
+ + GY VDIW+LG V+ M GK P+ F + K P
Sbjct: 1291 IYSYGEKDETTGSYSGYGRSVDIWALGATVVNMMTGKVPFEGQTRHQIAFALCFRKQKPT 1350
Query: 1264 IPDDTKDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPFCKTSSSF 1309
PD P + F D CFE P RPTA L+ F + +F
Sbjct: 1351 YPDIADK--RPDVKRFFDNCFEFLPNDRPTAAELLQTTFANVNITF 1394
>Hs19923464 [T] KOG0577 Serine/threonine protein kinase
Length = 898
Score = 137 bits (344), Expect = 1e-31
Identities = 87/264 (32%), Positives = 139/264 (51%), Gaps = 18/264 (6%)
Query: 1044 IGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHVNI 1103
IG GSFGAVY A N T E++A+K+++ + ++ + + EV L+ L H N
Sbjct: 30 IGHGSFGAVYFATNAHTNEVVAIKKMSYSGKQTHEKW-----QDILKEVKFLRQLKHPNT 84
Query: 1104 VQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGR-FDDQLIRHLTKQVLEGLAYLHSKGI 1162
++Y G K L +EY G S L+ ++ + + I +T L GLAYLHS +
Sbjct: 85 IEYKGCYLKEHTAWLVMEYCLG-SASDLLEVHKKPLQEVEIAAITHGALHGLAYLHSHAL 143
Query: 1163 LHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVDTAH--GY 1220
+HRD+KA N+LL G K++DFG + ++ S GT +WMAPE++ Y
Sbjct: 144 IHRDIKAGNILLTEPGQVKLADFGSASMASPANS-----FVGTPYWMAPEVILAMDEGQY 198
Query: 1221 SAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQSFL 1280
KVDIWSLG +E+ K P N ++A++ I ++ + ++ D + + F+
Sbjct: 199 DGKVDIWSLGITCIELAERKPPLFNMNAMSALYHIAQNDSPTLQSNEWTD----SFRRFV 254
Query: 1281 DQCFEIDPEMRPTADSLVGHPFCK 1304
D C + P+ RPT+ L+ H F +
Sbjct: 255 DYCLQKIPQERPTSAELLRHDFVR 278
>At2g24360 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 407
Score = 137 bits (344), Expect = 1e-31
Identities = 85/254 (33%), Positives = 132/254 (51%), Gaps = 13/254 (5%)
Query: 1041 GEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNH 1100
G +G+FG +Y GE +A+K + PE S E A M + + EVS L +L H
Sbjct: 129 GPAFAQGAFGKLYKG--TYNGEDVAIKILERPENSP--EKAQFMEQQFQQEVSMLANLKH 184
Query: 1101 VNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLI--RMYGRFDDQLIRHLTKQVLEGLAYLH 1158
NIV+++G K ++ + EY GGSV + R +L V G+AY+H
Sbjct: 185 PNIVRFIGACRKPMVWCIVTEYAKGGSVRQFLTRRQNRAVPLKLAVKQALDVARGMAYVH 244
Query: 1159 SKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVDTAH 1218
+ +HRD+K+DNLL+ D KI+DFG++R + + GT WMAPEM+
Sbjct: 245 GRNFIHRDLKSDNLLISADKSIKIADFGVAR--IEVQTEGMTPETGTYRWMAPEMIQ-HR 301
Query: 1219 GYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQS 1278
Y+ KVD++S G V+ E+ G P+ N V A F + P +P+D ++S
Sbjct: 302 AYNQKVDVYSFGIVLWELITGLLPFQNMTAVQAAFAVVNRGVRPTVPNDCLPVLS----D 357
Query: 1279 FLDQCFEIDPEMRP 1292
+ +C++ +PE+RP
Sbjct: 358 IMTRCWDANPEVRP 371
>7302458 [T] KOG0574 STE20-like serine/threonine kinase MST
Length = 596
Score = 137 bits (344), Expect = 1e-31
Identities = 86/288 (29%), Positives = 147/288 (50%), Gaps = 16/288 (5%)
Query: 1044 IGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHVNI 1103
+G+GS+G+VY A++ + ++A+K V V S + + E+S ++ + +
Sbjct: 48 LGEGSYGSVYKAVHKESSSIVAIKLVPVE----------SDLHEIIKEISIMQQCDSPYV 97
Query: 1104 VQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGR-FDDQLIRHLTKQVLEGLAYLHSKGI 1162
V+Y G K + +EY GSV ++R+ + + I + L+GL YLH +
Sbjct: 98 VRYYGSYFKQYDLWICMEYCGAGSVSDIMRLRKKTLTEDEIATILSDTLQGLVYLHLRRK 157
Query: 1163 LHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVDTAHGYSA 1222
+HRD+KA N+LL+ +G K++DFG++ + + + + T+ GT FWMAPE+++ GY
Sbjct: 158 IHRDIKAANILLNTEGYAKLADFGVAGQLTDTMAKRN-TVIGTPFWMAPEVIEEI-GYDC 215
Query: 1223 KVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQSFLDQ 1282
DIWSLG LEM GK P+ + A+F I + PP D S F+ +
Sbjct: 216 VADIWSLGITALEMAEGKPPYGEIHPMRAIFMIPQK---PPPSFREPDRWSTEFIDFVSK 272
Query: 1283 CFEIDPEMRPTADSLVGHPFCKTSSSFDFPKTKLAQFIKSNDKLNSSR 1330
C +P+ R TA L+ H F + + K L + ++ ++R
Sbjct: 273 CLVKEPDDRATATELLEHEFIRNAKHRSILKPMLEETCAIREQQRANR 320
>CE07737 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 1418
Score = 136 bits (342), Expect = 3e-31
Identities = 87/283 (30%), Positives = 140/283 (48%), Gaps = 26/283 (9%)
Query: 1036 FAWIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTL 1095
F W + I GSFG+V+ A+++ + ++A K + + + + A++SE++
Sbjct: 1123 FQWALLDHIASGSFGSVHRAMDIDSHRVIAAKVMRIQRENHK---------AIESEINIF 1173
Query: 1096 KDLNHVNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLA 1155
+ L H N+V+Y G + ++ +F+EY + G++ + +G+ D +++R T +L +
Sbjct: 1174 RQLIHENLVKYYGVQVEDSDVIIFMEYCSQGTLERIC--HGKMDLKMVRQYTNSLLRAVQ 1231
Query: 1156 YLHSKGILHRDMKADNLLLDNDGVCKISDFGISRK---SNNIYSNSDMTMRGTVFWMAPE 1212
YLHS I+HRD+K N+ LD V K+ DFG S + S+ +Y T GT +MAPE
Sbjct: 1232 YLHSHKIIHRDIKPANIFLDKCTVLKLGDFGCSSRLVESSTVYGEF-QTTAGTPQFMAPE 1290
Query: 1213 M---------VDTAHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPP 1263
+ + GY VDIW+LG V+ M GK P+ F + K P
Sbjct: 1291 IYSYGEKDETTGSYSGYGRSVDIWALGATVVNMMTGKVPFEGQTRHQIAFALCFRKQKPT 1350
Query: 1264 IPDDTKDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPFCKTS 1306
PD P + F D CFE P RPTA L+ F +
Sbjct: 1351 YPDIADK--RPDVKRFFDNCFEFLPNDRPTAAELLQTTFANVN 1391
>7293601 [T] KOG0577 Serine/threonine protein kinase
Length = 1039
Score = 136 bits (342), Expect = 3e-31
Identities = 90/262 (34%), Positives = 148/262 (56%), Gaps = 18/262 (6%)
Query: 1044 IGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHVNI 1103
IG GSFGAVY A T E++A+K+++ SQ++ + + E+ L+ LNH N
Sbjct: 33 IGHGSFGAVYYARCNLTREIVAIKKMSYTGKQSQEKW-----QDILKEIRFLRQLNHPNT 87
Query: 1104 VQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGR-FDDQLIRHLTKQVLEGLAYLHSKGI 1162
++Y G + L +EY G S +I ++ + + I + VL GL+YLHS G
Sbjct: 88 IEYKGCYLRESTAWLVMEYCVG-SASDIIEVHKKPLHEDEIAAICLGVLSGLSYLHSLGR 146
Query: 1163 LHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVDTAH--GY 1220
+HRD+KA N+LL ++GV K++DFG + + +NS + GT +WMAPE++ Y
Sbjct: 147 IHRDIKAGNILLTDNGVVKLADFGSA--AIKCPANSFV---GTPYWMAPEVILAMDEGQY 201
Query: 1221 SAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQSFL 1280
KVD+WSLG +E+ K P+ N ++A++ I +++ +P +P K+ S A SF+
Sbjct: 202 DGKVDVWSLGITCIELAERKPPYFNMNAMSALYHIAQNE-SPTLP---KNDWSDAFCSFV 257
Query: 1281 DQCFEIDPEMRPTADSLVGHPF 1302
+ C + P RP++ L+ H +
Sbjct: 258 ELCLKKMPAERPSSAKLLTHAY 279
>Hs5031975 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 591
Score = 135 bits (340), Expect = 4e-31
Identities = 87/262 (33%), Positives = 149/262 (56%), Gaps = 20/262 (7%)
Query: 1044 IGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHVNI 1103
IG+GS G V +A ++G+++AVK++ + + + E L +EV ++D H N+
Sbjct: 327 IGEGSTGIVCIATVRSSGKLVAVKKMDLRKQQRR--------ELLFNEVVIMRDYQHENV 378
Query: 1104 VQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHSKGIL 1163
V+ + +E++ GG++ ++ + R +++ I + VL+ L+ LH++G++
Sbjct: 379 VEMYNSYLVGDELWVVMEFLEGGALTDIVT-HTRMNEEQIAAVCLAVLQALSVLHAQGVI 437
Query: 1164 HRDMKADNLLLDNDGVCKISDFGI-SRKSNNIYSNSDMTMRGTVFWMAPEMVDTAHGYSA 1222
HRD+K+D++LL +DG K+SDFG ++ S + + GT +WMAPE++ Y
Sbjct: 438 HRDIKSDSILLTHDGRVKLSDFGFCAQVSKEVPRRKSLV--GTPYWMAPELISRL-PYGP 494
Query: 1223 KVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDL--VSPAGQSFL 1280
+VDIWSLG +V+EM G+ P+ N + AM I + +P K+L VSP+ + FL
Sbjct: 495 EVDIWSLGIMVIEMVDGEPPYFNEPPLKAMKMIRDN-----LPPRLKNLHKVSPSLKGFL 549
Query: 1281 DQCFEIDPEMRPTADSLVGHPF 1302
D+ DP R TA L+ HPF
Sbjct: 550 DRLLVRDPAQRATAAELLKHPF 571
>At5g40440 [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K)
Length = 520
Score = 135 bits (340), Expect = 4e-31
Identities = 94/284 (33%), Positives = 151/284 (53%), Gaps = 22/284 (7%)
Query: 1044 IGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLN-HVN 1102
IG G+ V A+++ +LA+K++ + E + + L +E+ TL + H
Sbjct: 89 IGSGASSVVQRAIHIPNHRILALKKINIFEREKRQQ--------LLTEIRTLCEAPCHEG 140
Query: 1103 IVQYLG--FEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHS- 1159
+V + G + +G S+ LEY+ GGS+ ++++ + + ++ L ++L+GL+YLH
Sbjct: 141 LVDFHGAFYSPDSGQISIALEYMNGGSLADILKVTKKIPEPVLSSLFHKLLQGLSYLHGV 200
Query: 1160 KGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVDTAHG 1219
+ ++HRD+K NLL++ G KI+DFGIS N + T GTV +M+PE +
Sbjct: 201 RHLVHRDIKPANLLINLKGEPKITDFGISAGLENSMAMC-ATFVGTVTYMSPERIRN-DS 258
Query: 1220 YSAKVDIWSLGCVVLEMFAGKRPW-SNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQS 1278
YS DIWSLG + E G+ P+ +N V M QI P P K SP S
Sbjct: 259 YSYPADIWSLGLALFECGTGEFPYIANEGPVNLMLQI----LDDPSPTPPKQEFSPEFCS 314
Query: 1279 FLDQCFEIDPEMRPTADSLVGHPFCKTSSSFDFPKTKLAQFIKS 1322
F+D C + DP+ RPTAD L+ HPF + + + LA F++S
Sbjct: 315 FIDACLQKDPDARPTADQLLSHPFI---TKHEKERVDLATFVQS 355
>At2g30040 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 463
Score = 134 bits (338), Expect = 7e-31
Identities = 97/292 (33%), Positives = 155/292 (52%), Gaps = 30/292 (10%)
Query: 1017 DKRTISINKSRNSRGEYKEFAWIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSS 1076
+K+ I N S +S +WI+G +G+G FG V AL+ G + AVK + +
Sbjct: 2 EKQNIISNTSSSSS------SWIRGSCVGRGCFGTVSKALSKIDGGLFAVKSIDLATCLP 55
Query: 1077 QDESAISMVEALKSEVSTLKDL-NHVNIVQYLGFE-EKNGIYS---LFLEYVAGGSVGSL 1131
S E+L++E+ L+ + +H NIV++LG + K G S L LEY G V +
Sbjct: 56 ------SQAESLENEIVILRSMKSHPNIVRFLGDDVSKEGTASFRNLHLEYSPEGDVAN- 108
Query: 1132 IRMYGRFDDQLIRHLTKQVLEGLAYLHSKGILHRDMKADNLLLDNDGVC-KISDFGISRK 1190
G ++ L+R ++ L+++HS GI+H D+K+ N+L+ N G K++DFG + +
Sbjct: 109 ---GGIVNETLLRRYVWCLVSALSHVHSNGIVHCDVKSKNVLVFNGGSSVKLADFGSAVE 165
Query: 1191 SNNIYSNSDMTMRGTVFWMAPEMVDTAHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVA 1250
S ++ RG+ WMAPE+V + + D+WSLGC V+EM GK W +
Sbjct: 166 FEK--STIHVSPRGSPLWMAPEVVRREY-QGPESDVWSLGCTVIEMLTGKPAWED-HGFD 221
Query: 1251 AMFQIGKSKTAPPIPDDTKDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPF 1302
++ +IG S P IP +L G+ FL++C + D R + D L+ HPF
Sbjct: 222 SLSRIGFSNDLPFIPVGLSEL----GRDFLEKCLKRDRSQRWSCDQLLQHPF 269
>Hs7706401 [T] KOG0577 Serine/threonine protein kinase
Length = 1235
Score = 134 bits (337), Expect = 1e-30
Identities = 88/262 (33%), Positives = 143/262 (53%), Gaps = 18/262 (6%)
Query: 1044 IGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHVNI 1103
IG GSFGAVY A +V E++A+K+++ S ++ + + EV L+ L H N
Sbjct: 34 IGHGSFGAVYFARDVRNSEVVAIKKMSYSGKQSNEKW-----QDIIKEVRFLQKLRHPNT 88
Query: 1104 VQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGR-FDDQLIRHLTKQVLEGLAYLHSKGI 1162
+QY G + L +EY G S L+ ++ + + I +T L+GLAYLHS +
Sbjct: 89 IQYRGCYLREHTAWLVMEYCLG-SASDLLEVHKKPLQEVEIAAVTHGALQGLAYLHSHNM 147
Query: 1163 LHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVDTAH--GY 1220
+HRD+KA N+LL G+ K+ DFG S +I + ++ + GT +WMAPE++ Y
Sbjct: 148 IHRDVKAGNILLSEPGLVKLGDFG----SASIMAPAN-SFVGTPYWMAPEVILAMDEGQY 202
Query: 1221 SAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQSFL 1280
KVD+WSLG +E+ K P N ++A++ I ++++ P S ++F+
Sbjct: 203 DGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQNES----PVLQSGHWSEYFRNFV 258
Query: 1281 DQCFEIDPEMRPTADSLVGHPF 1302
D C + P+ RPT++ L+ H F
Sbjct: 259 DSCLQKIPQDRPTSEVLLKHRF 280
>Hs4759208 [T] KOG0577 Serine/threonine protein kinase
Length = 1049
Score = 134 bits (337), Expect = 1e-30
Identities = 88/262 (33%), Positives = 143/262 (53%), Gaps = 18/262 (6%)
Query: 1044 IGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHVNI 1103
IG GSFGAVY A +V E++A+K+++ S ++ + + EV L+ L H N
Sbjct: 34 IGHGSFGAVYFARDVRNSEVVAIKKMSYSGKQSNEKW-----QDIIKEVRFLQKLRHPNT 88
Query: 1104 VQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGR-FDDQLIRHLTKQVLEGLAYLHSKGI 1162
+QY G + L +EY G S L+ ++ + + I +T L+GLAYLHS +
Sbjct: 89 IQYRGCYLREHTAWLVMEYCLG-SASDLLEVHKKPLQEVEIAAVTHGALQGLAYLHSHNM 147
Query: 1163 LHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVDTAH--GY 1220
+HRD+KA N+LL G+ K+ DFG S +I + ++ + GT +WMAPE++ Y
Sbjct: 148 IHRDVKAGNILLSEPGLVKLGDFG----SASIMAPAN-SFVGTPYWMAPEVILAMDEGQY 202
Query: 1221 SAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQSFL 1280
KVD+WSLG +E+ K P N ++A++ I ++++ P S ++F+
Sbjct: 203 DGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQNES----PVLQSGHWSEYFRNFV 258
Query: 1281 DQCFEIDPEMRPTADSLVGHPF 1302
D C + P+ RPT++ L+ H F
Sbjct: 259 DSCLQKIPQDRPTSEVLLKHRF 280
>Hs5174701 [T] KOG0579 Ste20-like serine/threonine protein kinase
Length = 968
Score = 134 bits (336), Expect = 1e-30
Identities = 96/282 (34%), Positives = 149/282 (52%), Gaps = 32/282 (11%)
Query: 1039 IKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDL 1098
I GE+ G G+FG VY A N TG + A K + E S++E +E E+ L
Sbjct: 38 IVGEL-GDGAFGKVYKAKNKETGALAAAKVI---ETKSEEE-----LEDYIVEIEILATC 88
Query: 1099 NHVNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGR-FDDQLIRHLTKQVLEGLAYL 1157
+H IV+ LG +G + +E+ GG+V +++ R + I+ + +Q+LE L +L
Sbjct: 89 DHPYIVKLLGAYYHDGKLWIMIEFCPGGAVDAIMLELDRGLTEPQIQVVCRQMLEALNFL 148
Query: 1158 HSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMV--- 1214
HSK I+HRD+KA N+L+ +G +++DFG+S K+ D + GT +WMAPE+V
Sbjct: 149 HSKRIIHRDLKAGNVLMTLEGDIRLADFGVSAKNLKTLQKRD-SFIGTPYWMAPEVVMCE 207
Query: 1215 ---DTAHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDL 1271
DT + Y K DIWSLG ++EM + P + + +I KS D L
Sbjct: 208 TMKDTPYDY--KADIWSLGITLIEMAQIEPPHHELNPMRVLLKIAKS--------DPPTL 257
Query: 1272 VSPAGQS-----FLDQCFEIDPEMRPTADSLVGHPFCKTSSS 1308
++P+ S FL + +PE RP+A L+ HPF + +S
Sbjct: 258 LTPSKWSVEFRDFLKIALDKNPETRPSAAQLLEHPFVSSITS 299
>Hs7019543 [T] KOG0582 Ste20-like serine/threonine protein kinase
Length = 547
Score = 132 bits (332), Expect = 4e-30
Identities = 91/294 (30%), Positives = 151/294 (50%), Gaps = 29/294 (9%)
Query: 1042 EIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHV 1101
E+IG G+ V AL E +A+K++ + ++ SM E LK E+ + +H
Sbjct: 69 EVIGSGATAVVQAALCKPRQERVAIKRINL------EKCQTSMDELLK-EIQAMSQCSHP 121
Query: 1102 NIVQYL-GFEEKNGIYSLFLEYVAGGSVGSLIRMY--------GRFDDQLIRHLTKQVLE 1152
N+V Y F K+ ++ L ++ ++GGS+ +I+ G ++ +I + K+VLE
Sbjct: 122 NVVTYYTSFVVKDELW-LVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLE 180
Query: 1153 GLAYLHSKGILHRDMKADNLLLDNDGVCKISDFGIS---RKSNNIYSNS-DMTMRGTVFW 1208
GL YLH G +HRD+KA N+LL DG +I+DFG+S ++ N T GT W
Sbjct: 181 GLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCW 240
Query: 1209 MAPEMVDTAHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPD-- 1266
MAPE+++ GY K D+WS G +E+ G P+ + + + + PP +
Sbjct: 241 MAPEVMEQVRGYDFKADMWSFGITAIELATGAAPYHKYPPMKVLML--TLQNDPPTLETG 298
Query: 1267 -DTKDLVSPAGQSF---LDQCFEIDPEMRPTADSLVGHPFCKTSSSFDFPKTKL 1316
+ K+++ G+SF L C + DP RPTA L+ F + + + ++ KL
Sbjct: 299 VEDKEMMKKYGKSFRKLLSLCLQKDPSKRPTAAELLKCKFFQKAKNREYLIEKL 352
>At4g10010 [D] KOG0600 Cdc2-related protein kinase
Length = 649
Score = 132 bits (332), Expect = 4e-30
Identities = 95/308 (30%), Positives = 154/308 (49%), Gaps = 46/308 (14%)
Query: 1044 IGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHVNI 1103
IG+G++ +VY A ++ TG+M+A+K+V F + D ++ + E++ L+ L+H N+
Sbjct: 162 IGQGTYSSVYRARDLETGKMVAMKKV---RFVNMDPESVRF---MAREINILRKLDHPNV 215
Query: 1104 VQY--LGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHSKG 1161
++ L + +G L EY+ G +R +F + I+ KQ+L GL + HS+G
Sbjct: 216 MKLECLVTSKLSGSLYLVFEYMEHDLSGLALRPGVKFTESQIKCYMKQLLSGLEHCHSRG 275
Query: 1162 ILHRDMKADNLLLDNDGVCKISDFGISRKSNNIY---SNSDMTMRGTVFW-MAPEMVDTA 1217
ILHRD+K NLL++NDGV KI DFG++ NIY + +T R W APE++ A
Sbjct: 276 ILHRDIKGPNLLVNNDGVLKIGDFGLA----NIYHPEQDQPLTSRVVTLWYRAPELLLGA 331
Query: 1218 HGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGK----------SKTAPPIPD- 1266
Y +D+WS+GC++ E+F GK V M +I K KT P+
Sbjct: 332 TEYGPGIDLWSVGCILTELFLGKPIMPGRTEVEQMHKIFKFCGSPSDDYWQKTKLPLATS 391
Query: 1267 ------------DTKDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPF-------CKTSS 1307
+T + P+ + +D+ ++P R TA S + F C SS
Sbjct: 392 FKPQQPYKRVLLETFKNLPPSALALVDKLLSLEPAKRGTASSTLSSKFFTMEPLPCNVSS 451
Query: 1308 SFDFPKTK 1315
+P +K
Sbjct: 452 LPKYPPSK 459
>YDR523c [T] KOG0201 Serine/threonine protein kinase
Length = 490
Score = 132 bits (331), Expect = 5e-30
Identities = 91/284 (32%), Positives = 139/284 (48%), Gaps = 23/284 (8%)
Query: 1044 IGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHVNI 1103
IG+G+FG VY A++ T E++A+K V + E S +D +E L E+ L +L I
Sbjct: 24 IGRGNFGDVYKAVDRVTQEIVAIKVVNL-EHSDED------IELLAQEIFFLAELKSPLI 76
Query: 1104 VQYLGFEEKNGIYSLFLEYVAGGSVGSLIRM--YGRFDDQLIRHLTKQVLEGLAYLHSKG 1161
Y+ ++ + +EY GGS L++ ++ + + +V GL YLH +
Sbjct: 77 TNYIATMLEDVSMWIVMEYCGGGSCSDLLKRSYVNGLPEEKVSFIIHEVTLGLKYLHEQR 136
Query: 1162 ILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMV-DTAHGY 1220
+HRD+KA N+LL+ +G+ K+ DFG+S + T GT +WMAPE+V GY
Sbjct: 137 KIHRDIKAANILLNEEGMVKLGDFGVSGHIRSTLKRD--TFVGTPYWMAPEVVCCEVDGY 194
Query: 1221 SAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQSFL 1280
+ K DIWSLG E+ G P S ++ + M + K K P + S A + F+
Sbjct: 195 NEKADIWSLGITTYELLKGLPPLSKYDPMKVMTNLPKRK-----PPKLQGPFSDAAKDFV 249
Query: 1281 DQCFEIDPEMRPTADSLVGHPFCKT------SSSFDFPKTKLAQ 1318
C P RP+A +L+ F K S D K K Q
Sbjct: 250 AGCLVKTPADRPSAYNLLSFEFVKNITITNLKSDVDLIKQKKVQ 293
>Hs8393810_1 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 336
Score = 132 bits (331), Expect = 5e-30
Identities = 96/300 (32%), Positives = 149/300 (49%), Gaps = 32/300 (10%)
Query: 1038 WIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKD 1097
W E IGKG++G V+ LN G+ AVK + + + E +++E + LK
Sbjct: 21 WEITETIGKGTYGKVFKVLNKKNGQKAAVKIL---------DPIHDIDEEIEAEYNILKA 71
Query: 1098 LN-HVNIVQYLGFEEKNGIYS-----LFLEYVAGGSVGSLIRMY----GRFDDQLIRHLT 1147
L+ H N+V++ G K + L LE +GGSV L++ + R + LI ++
Sbjct: 72 LSDHPNVVRFYGIYFKKDKVNGDKLWLVLELCSGGSVTDLVKGFLKRGERMSEPLIAYIL 131
Query: 1148 KQVLEGLAYLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVF 1207
+ L GL +LH+ +HRD+K +N+LL +G K+ DFG+S + + + T GT F
Sbjct: 132 HEALMGLQHLHNNKTIHRDVKGNNILLTTEGGVKLVDFGVSAQLTSTRHRRN-TSVGTPF 190
Query: 1208 WMAPEMV------DTAHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTA 1261
WMAPE++ DT Y A+ D WSLG +E+ G P ++ + A+F+I ++
Sbjct: 191 WMAPEVIACEQQLDTT--YDARCDTWSLGITAIELGDGDPPLADLHPMRALFKIPRN--- 245
Query: 1262 PPIPDDTKDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPFCKTSSSFDFPKTK-LAQFI 1320
PP +L S F+ +C D E RPT L+ H F D K L +FI
Sbjct: 246 PPPKLRQPELWSAEFNDFISKCLTKDYEKRPTVSELLQHKFITQIEGKDVMLQKQLTEFI 305
>Hs20544910_1 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 336
Score = 132 bits (331), Expect = 5e-30
Identities = 96/300 (32%), Positives = 149/300 (49%), Gaps = 32/300 (10%)
Query: 1038 WIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKD 1097
W E IGKG++G V+ LN G+ AVK + + + E +++E + LK
Sbjct: 21 WEITETIGKGTYGKVFKVLNKKNGQKAAVKIL---------DPIHDIDEEIEAEYNILKA 71
Query: 1098 LN-HVNIVQYLGFEEKNGIYS-----LFLEYVAGGSVGSLIRMY----GRFDDQLIRHLT 1147
L+ H N+V++ G K + L LE +GGSV L++ + R + LI ++
Sbjct: 72 LSDHPNVVRFYGIYFKKDKVNGDKLWLVLELCSGGSVTDLVKGFLKRGERMSEPLIAYIL 131
Query: 1148 KQVLEGLAYLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVF 1207
+ L GL +LH+ +HRD+K +N+LL +G K+ DFG+S + + + T GT F
Sbjct: 132 HEALMGLQHLHNNKTIHRDVKGNNILLTTEGGVKLVDFGVSAQLTSTRHRRN-TSVGTPF 190
Query: 1208 WMAPEMV------DTAHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTA 1261
WMAPE++ DT Y A+ D WSLG +E+ G P ++ + A+F+I ++
Sbjct: 191 WMAPEVIACEQQLDTT--YDARCDTWSLGITAIELGDGDPPLADLHPMRALFKIPRN--- 245
Query: 1262 PPIPDDTKDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPFCKTSSSFDFPKTK-LAQFI 1320
PP +L S F+ +C D E RPT L+ H F D K L +FI
Sbjct: 246 PPPKLRQPELWSAEFNDFISKCLTKDYEKRPTVSELLQHKFITQIEGKDVMLQKQLTEFI 305
>At4g26070 [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K)
Length = 354
Score = 131 bits (330), Expect = 6e-30
Identities = 89/275 (32%), Positives = 153/275 (55%), Gaps = 17/275 (6%)
Query: 1042 EIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHV 1101
++IGKGS G V L + T + A+K + + ++++ + ++ + L+ +S+
Sbjct: 72 KVIGKGSSGNVQLVKHKLTQQFFALKVI---QLNTEESTCRAISQELRINLSSQCPYL-- 126
Query: 1102 NIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYL-HSK 1160
+ Y F NG+ S+ LE++ GGS+ L++ G+ + ++ + K+VL GL Y+ H +
Sbjct: 127 -VSCYQSFYH-NGLVSIILEFMDGGSLADLLKKVGKVPENMLSAICKRVLRGLCYIHHER 184
Query: 1161 GILHRDMKADNLLLDNDGVCKISDFGISR--KSNNIYSNSDMTMRGTVFWMAPEMVDTAH 1218
I+HRD+K NLL+++ G KI+DFG+S+ S + +NS + GT +M+PE + +
Sbjct: 185 RIIHRDLKPSNLLINHRGEVKITDFGVSKILTSTSSLANSFV---GTYPYMSPERI-SGS 240
Query: 1219 GYSAKVDIWSLGCVVLEMFAGKRPWSNFEVV---AAMFQIGKSKTAPPIPDDTKDLVSPA 1275
YS K DIWSLG V+LE GK P++ E ++++++ + P P +L SP
Sbjct: 241 LYSNKSDIWSLGLVLLECATGKFPYTPPEHKKGWSSVYELVDAIVENPPPCAPSNLFSPE 300
Query: 1276 GQSFLDQCFEIDPEMRPTADSLVGHPFCKTSSSFD 1310
SF+ QC + DP R +A L+ H F K D
Sbjct: 301 FCSFISQCVQKDPRDRKSAKELLEHKFVKMFEDSD 335
>At2g30360 [T] KOG0583 Serine/threonine protein kinase
Length = 435
Score = 131 bits (330), Expect = 6e-30
Identities = 79/263 (30%), Positives = 144/263 (54%), Gaps = 11/263 (4%)
Query: 1041 GEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNH 1100
G+++G G+F V+ A + TG+ +AVK + + + ++ +K E+S ++ L+H
Sbjct: 24 GKLLGCGAFAKVFHARDRRTGQSVAVKILNKKKLLTNP----ALANNIKREISIMRRLSH 79
Query: 1101 VNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHSK 1160
NIV+ +E+V GG + + I +GR + L R +Q++ + Y H++
Sbjct: 80 PNIVKLHEVMATKSKIFFAMEFVKGGELFNKISKHGRLSEDLSRRYFQQLISAVGYCHAR 139
Query: 1161 GILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDM-TMRGTVFWMAPEMVDTAHG 1219
G+ HRD+K +NLL+D +G K+SDFG+S ++ I + + T+ GT ++APE++
Sbjct: 140 GVYHRDLKPENLLIDENGNLKVSDFGLSALTDQIRPDGLLHTLCGTPAYVAPEILSKKGY 199
Query: 1220 YSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQSF 1279
AKVD+WS G V+ + AG P+++ V+ +I K + P +SP + F
Sbjct: 200 EGAKVDVWSCGIVLFVLVAGYLPFNDPNVMNMYKKIYKGEYRFP------RWMSPDLKRF 253
Query: 1280 LDQCFEIDPEMRPTADSLVGHPF 1302
+ + +I+PE R T D ++ P+
Sbjct: 254 VSRLLDINPETRITIDEILKDPW 276
>CE07599 [T] KOG0576 Mitogen-activated protein kinase kinase kinase kinase
(MAP4K) germinal center kinase family
Length = 829
Score = 131 bits (329), Expect = 8e-30
Identities = 78/268 (29%), Positives = 138/268 (51%), Gaps = 13/268 (4%)
Query: 1044 IGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHVNI 1103
+G G++G VY A ++ + + AVK V + + D A+ ++ E+ +++ +H NI
Sbjct: 21 VGSGTYGEVYKARDIRSDSLAAVKVV---KLEAGDNFAV-----IQQEIMVIRECSHPNI 72
Query: 1104 VQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHSKGIL 1163
+ Y G + + +EY GGS+ + + G + I + ++ L GL YLH+ G +
Sbjct: 73 IAYFGSYIRRDRLWIVMEYCGGGSLQDIYHLTGPLSELQIAFVCRETLRGLNYLHNMGKI 132
Query: 1164 HRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEM--VDTAHGYS 1221
HRD+K N+LL + G K++DFG++ + + GT +WMAPE+ V+ GY
Sbjct: 133 HRDIKGANILLSSSGDVKLADFGVAAQITATIGKR-KSFIGTPYWMAPEVACVEKRGGYG 191
Query: 1222 AKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQSFLD 1281
+ D+W+ G +E+ + P + + ++ + KS PP D K +P F+
Sbjct: 192 MQCDVWATGITAIELGECQPPLFDLHPMQVLYLMTKSGYKPPHLKD-KHRWTPLFHDFVR 250
Query: 1282 QCFEIDPEMRPTADSLV-GHPFCKTSSS 1308
QC +P+ RP+ + L+ HPF S S
Sbjct: 251 QCLTKNPKKRPSPEKLLTSHPFVLGSLS 278
>Hs20428779_1 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 357
Score = 130 bits (328), Expect = 1e-29
Identities = 94/283 (33%), Positives = 140/283 (49%), Gaps = 31/283 (10%)
Query: 1038 WIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKD 1097
W E IGKG++G VY N G + AVK + + M E +++E + L+
Sbjct: 27 WEIIETIGKGTYGKVYKVTNKRDGSLAAVKIL---------DPVSDMDEEIEAEYNILQF 77
Query: 1098 L-NHVNIVQYLGFEEK-----NGIYSLFLEYVAGGSVGSLI----RMYGRFDDQLIRHLT 1147
L NH N+V++ G K G L LE GGSV L+ R R D+ +I ++
Sbjct: 78 LPNHPNVVKFYGMFYKADHCVGGQLWLVLELCNGGSVTELVKGLLRCGQRLDEAMISYIL 137
Query: 1148 KQVLEGLAYLHSKGILHRDMKADNLLLDNDGVCKISDFGISRK--SNNIYSNSDMTMRGT 1205
L GL +LH+ I+HRD+K +N+LL +G K+ DFG+S + S + N+ + GT
Sbjct: 138 YGALLGLQHLHNNRIIHRDVKGNNILLTTEGGVKLVDFGVSAQLTSTRLRRNTSV---GT 194
Query: 1206 VFWMAPEMVDTAH----GYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTA 1261
FWMAPE++ Y A+ D+WSLG +E+ G P + V +F+I ++
Sbjct: 195 PFWMAPEVIACEQQYDSSYDARCDVWSLGITAIELGDGDPPLFDMHPVKTLFKIPRN--- 251
Query: 1262 PPIPDDTKDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPFCK 1304
PP + F+ QC D E RP+ L+ HPF K
Sbjct: 252 PPPTLLHPEKWCEEFNHFISQCLIKDFERRPSVTHLLDHPFIK 294
>At4g31170 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 412
Score = 130 bits (327), Expect = 1e-29
Identities = 84/260 (32%), Positives = 129/260 (49%), Gaps = 13/260 (5%)
Query: 1041 GEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNH 1100
G +G+FG +Y GE +A+K + S E A ++ + + EVS L L H
Sbjct: 134 GPAFAQGAFGKLYRG--TYNGEDVAIK--LLERSDSNPEKAQALEQQFQQEVSMLAFLKH 189
Query: 1101 VNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLI--RMYGRFDDQLIRHLTKQVLEGLAYLH 1158
NIV+++G K ++ + EY GGSV + R +L V G+AY+H
Sbjct: 190 PNIVRFIGACIKPMVWCIVTEYAKGGSVRQFLTKRQNRAVPLKLAVMQALDVARGMAYVH 249
Query: 1159 SKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVDTAH 1218
+ +HRD+K+DNLL+ D KI+DFG++R + + GT WMAPEM+
Sbjct: 250 ERNFIHRDLKSDNLLISADRSIKIADFGVAR--IEVQTEGMTPETGTYRWMAPEMIQ-HR 306
Query: 1219 GYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQS 1278
Y+ KVD++S G V+ E+ G P+ N V A F + P +P D P
Sbjct: 307 PYTQKVDVYSFGIVLWELITGLLPFQNMTAVQAAFAVVNRGVRPTVPAD----CLPVLGE 362
Query: 1279 FLDQCFEIDPEMRPTADSLV 1298
+ +C++ DPE+RP +V
Sbjct: 363 IMTRCWDADPEVRPCFAEIV 382
>Hs7661994 [T] KOG0579 Ste20-like serine/threonine protein kinase
Length = 1152
Score = 130 bits (326), Expect = 2e-29
Identities = 94/281 (33%), Positives = 146/281 (51%), Gaps = 20/281 (7%)
Query: 1034 KEFAWIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVS 1093
++F I GE+ G G+FG VY A N T + A K + + S++E MVE +
Sbjct: 31 EDFWEIIGEL-GDGAFGKVYKAQNKETSVLAAAKVI---DTKSEEELEDYMVE-----ID 81
Query: 1094 TLKDLNHVNIVQYL-GFEEKNGIYSLFLEYVAGGSVGSLIRMYGR-FDDQLIRHLTKQVL 1151
L +H NIV+ L F +N ++ L +E+ AGG+V +++ R + I+ + KQ L
Sbjct: 82 ILASCDHPNIVKLLDAFYYENNLWIL-IEFCAGGAVDAVMLELERPLTESQIQVVCKQTL 140
Query: 1152 EGLAYLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAP 1211
+ L YLH I+HRD+KA N+L DG K++DFG+S K+ D + GT +WMAP
Sbjct: 141 DALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRD-SFIGTPYWMAP 199
Query: 1212 EMV----DTAHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDD 1267
E+V Y K D+WSLG ++EM + P + + +I KS+ P +
Sbjct: 200 EVVMCETSKDRPYDYKADVWSLGITLIEMAEIEPPHHELNPMRVLLKIAKSE-PPTLAQP 258
Query: 1268 TKDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPFCKTSSS 1308
++ S + FL +C E + + R T L+ HPF S+
Sbjct: 259 SR--WSSNFKDFLKKCLEKNVDARWTTSQLLQHPFVTVDSN 297
>Hs13376582 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 168
Score = 130 bits (326), Expect = 2e-29
Identities = 63/153 (41%), Positives = 98/153 (63%), Gaps = 7/153 (4%)
Query: 1120 LEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHSKGILHRDMKADNLLLDNDGV 1179
+E+V GGS+ S+I +G + + TKQ+L+G+AYLH ++HRD+K +N++L G+
Sbjct: 1 MEFVPGGSISSIINRFGPLPEMVFCKYTKQILQGVAYLHENCVVHRDIKGNNVMLMPTGI 60
Query: 1180 CKISDFGISRK-----SNNIYSNSDMTMRGTVFWMAPEMVDTAHGYSAKVDIWSLGCVVL 1234
K+ DFG +R+ N +S+ +M GT +WM PE+++ + GY K DIWS+GC V
Sbjct: 61 IKLIDFGCARRLAWAGLNGTHSDMLKSMHGTPYWMVPEVINES-GYGRKSDIWSIGCTVF 119
Query: 1235 EMFAGKRPWSNFEVVAAMFQIGKSK-TAPPIPD 1266
EM GK P ++ + +AAMF IG + PP+PD
Sbjct: 120 EMATGKPPLASMDRMAAMFYIGAHRGLMPPLPD 152
>SPBC17F3.02 [T] KOG0201 Serine/threonine protein kinase
Length = 652
Score = 129 bits (324), Expect = 3e-29
Identities = 86/287 (29%), Positives = 145/287 (49%), Gaps = 13/287 (4%)
Query: 1038 WIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKD 1097
+ K E++G+GS+GAVY + T E +A+K + + DE +S ++ + +S LK
Sbjct: 10 YTKLELVGRGSYGAVYRGICNLTKETVAIKILNL----DTDEDEVSDIQKEVAVLSELKQ 65
Query: 1098 LNHVNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYL 1157
+ NI++Y G + ++Y GGSV +L+ G + I + ++ L+ L ++
Sbjct: 66 SDVENIIKYHGSYLVGTNLWIIMDYCHGGSVRTLMEA-GPISEPCISLILRETLQALKFI 124
Query: 1158 HSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVDTA 1217
H GI+HRD+KA N+L+ G K+ DFG++ + NI +T GT +WMAPE++
Sbjct: 125 HHAGIIHRDIKAANILVSMSGNVKLCDFGVAAEL-NINRRKRITFIGTPYWMAPEVIRDG 183
Query: 1218 HGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQ 1277
Y+ DIWSLG E+ G P + + A++ I + TAPP + S +
Sbjct: 184 QEYNVMADIWSLGITAYEIATGSPPHAKEDPFRAVYLI--AHTAPPRLNGN---FSALLK 238
Query: 1278 SFLDQCFEIDPEMRPTADSLVGHPFCKTSSSFDFPKTKLAQFIKSND 1324
F+ C + P+ R + L+ F K S ++L +K D
Sbjct: 239 EFIASCLQDVPQRRLDSSELLKSKFIKQYSRMSI--SELTNVVKRYD 283
>At5g56580 [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K)
Length = 356
Score = 129 bits (323), Expect = 4e-29
Identities = 95/274 (34%), Positives = 142/274 (51%), Gaps = 26/274 (9%)
Query: 1042 EIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHV 1101
++IGKGS G V L + G+ A+K + + + Q+E +V+ LK ++ HV
Sbjct: 74 KVIGKGSGGVVQLVRHKWVGKFFAMKVI---QMNIQEEIRKQIVQELKINQAS-SQCPHV 129
Query: 1102 NIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHS-K 1160
+V Y F NG +SL LEY+ GS+ +IR + + + KQVL GL YLH+ +
Sbjct: 130 -VVCYHSFYH-NGAFSLVLEYMDRGSLADVIRQVKTILEPYLAVVCKQVLLGLVYLHNER 187
Query: 1161 GILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVDTAHGY 1220
++HRD+K NLL+++ G KISDFG+S + D T GT +M+PE + + Y
Sbjct: 188 HVIHRDIKPSNLLVNHKGEVKISDFGVSASLASSMGQRD-TFVGTYNYMSPERI-SGSTY 245
Query: 1221 SAKVDIWSLGCVVLEMFAGKRPW----------SNFEVVAAMFQIGKSKTAPPIPDDTKD 1270
DIWSLG VLE G+ P+ S +E++AA+ + P P D
Sbjct: 246 DYSSDIWSLGMSVLECAIGRFPYLESEDQQNPPSFYELLAAIVE-------NPPPTAPSD 298
Query: 1271 LVSPAGQSFLDQCFEIDPEMRPTADSLVGHPFCK 1304
SP SF+ C + DP R ++ L+ HPF K
Sbjct: 299 QFSPEFCSFVSACIQKDPPARASSLDLLSHPFIK 332
>YOL113w [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 655
Score = 128 bits (322), Expect = 5e-29
Identities = 89/305 (29%), Positives = 152/305 (49%), Gaps = 46/305 (15%)
Query: 1042 EIIGKGSFGAVYLALNV-----------------TTGEMLAVKQVTVPEFSSQDESAISM 1084
E G+G+ GAVYL+ + GE +A+KQ+ + E +
Sbjct: 364 EKAGQGASGAVYLSKRIKLPQENDPRFLKSHCHRVVGERVAIKQIRLSEQPKK------- 416
Query: 1085 VEALKSEVSTLKDLNHVNIVQYL-GFEEKNGIYSLFLEYVAGGSVGSLIRMYGR------ 1137
+ + +E+ + D NIV +L + + + +EY+ GG + ++ R
Sbjct: 417 -QLIMNELLVMNDSRQENIVNFLEAYIIDDEELWVIMEYMEGGCLTDILDAVARSNTGEH 475
Query: 1138 ---FDDQLIRHLTKQVLEGLAYLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNI 1194
++ + ++ K+ +GL +LH+K I+HRD+K+DN+LL++ G+ KI+DFG +
Sbjct: 476 SSPLNENQMAYIVKETCQGLKFLHNKKIIHRDIKSDNILLNSQGLVKITDFGFCVELTEK 535
Query: 1195 YSNSDMTMRGTVFWMAPEMVDTAHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQ 1254
S TM GT +WMAPE+V+ GY KVD+WSLG +++EM G+ P+ N + + A++
Sbjct: 536 RSKR-ATMVGTPYWMAPEIVN-QKGYDEKVDVWSLGIMLIEMIEGEPPYLNEDPLKALYL 593
Query: 1255 I---GKSKTAPPIPDDTKDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPFCKTSSSFDF 1311
I G K P + VS + FLD C +++ E R + L+ F + S +
Sbjct: 594 IANNGSPKLRHP------ESVSKQTKQFLDACLQVNVESRASVRKLLTFEFLSMACSPEQ 647
Query: 1312 PKTKL 1316
K L
Sbjct: 648 LKVSL 652
>SPCC320.12c [D] KOG0580 Serine/threonine protein kinase
Length = 384
Score = 128 bits (322), Expect = 5e-29
Identities = 99/336 (29%), Positives = 171/336 (50%), Gaps = 28/336 (8%)
Query: 975 PKRTKTIRIIAQEASEARKNEVSQKLQRKNTKMWGTKVVEITDKRTISINKSRNSRG-EY 1033
P R + +R+ +++ + N VS ++N + +K K I +S G ++
Sbjct: 53 PGRQQLLRLAV--SNQRQVNNVSLANGKENKRTSNSKFNSSLRKIEEPIAGVPSSAGPQW 110
Query: 1034 KEF---AWIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKS 1090
+EF + G+ +GKG FG VYLA TG ++A+K + E + + ++
Sbjct: 111 REFHIGMFEIGKPLGKGKFGRVYLAKEKKTGFIVALKTLHKSELVQS-----KIEKQVRR 165
Query: 1091 EVSTLKDLNHVNIVQYLG-FEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQ 1149
E+ +L H NI++ G F ++ IY L LE+ G + +R RF +++ Q
Sbjct: 166 EIEIQSNLRHKNILRLYGHFHDEKRIY-LILEFAGRGELYQHLRRAKRFSEEVASKYIFQ 224
Query: 1150 VLEGLAYLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWM 1209
+ L+YLH K ++HRD+K +N+LL DG K+SDFG S + SN T+ GT+ ++
Sbjct: 225 MANALSYLHKKHVIHRDIKPENILLGIDGEIKLSDFGWSVHAP---SNRRTTLCGTLDYL 281
Query: 1210 APEMVDTAHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMF-QIGKSKTAPP--IPD 1266
PEMV+ ++ KVD+WSLG + E G P+ + +A + +I K P +P
Sbjct: 282 PPEMVE-GKEHTEKVDLWSLGVLTYEFLVGAPPFEDMSGHSATYKRIAKVDLKIPSFVPP 340
Query: 1267 DTKDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPF 1302
D +DL+S + + +PE R + + ++ HP+
Sbjct: 341 DARDLIS--------RLLQHNPEKRMSLEQVMRHPW 368
>Hs7661974 [T] KOG0583 Serine/threonine protein kinase
Length = 651
Score = 128 bits (322), Expect = 5e-29
Identities = 83/284 (29%), Positives = 139/284 (48%), Gaps = 15/284 (5%)
Query: 1042 EIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHV 1101
E IG G F V LA ++ TGEM+A+K + S + +K+E+ LK+L H
Sbjct: 15 ETIGTGGFAKVKLACHILTGEMVAIKIMDKNTLGSD-------LPRIKTEIEALKNLRHQ 67
Query: 1102 NIVQ-YLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHSK 1160
+I Q Y E N I+ + LEY GG + I R ++ R + +Q++ +AY+HS+
Sbjct: 68 HICQLYHVLETANKIF-MVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQ 126
Query: 1161 GILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVDTAHGY 1220
G HRD+K +NLL D K+ DFG+ K T G++ + APE++
Sbjct: 127 GYAHRDLKPENLLFDEYHKLKLIDFGLCAKPKGNKDYHLQTCCGSLAYAAPELIQGKSYL 186
Query: 1221 SAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQSFL 1280
++ D+WS+G ++ + G P+ + V+A +I + K D +SP+ L
Sbjct: 187 GSEADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKY------DVPKWLSPSSILLL 240
Query: 1281 DQCFEIDPEMRPTADSLVGHPFCKTSSSFDFPKTKLAQFIKSND 1324
Q ++DP+ R + +L+ HP+ ++ FI +D
Sbjct: 241 QQMLQVDPKKRISMKNLLNHPWIMQDYNYPVEWQSKNPFIHLDD 284
>At4g18700 [T] KOG0583 Serine/threonine protein kinase
Length = 489
Score = 127 bits (319), Expect = 1e-28
Identities = 86/287 (29%), Positives = 145/287 (49%), Gaps = 13/287 (4%)
Query: 1019 RTISINKSRNSRGEYKEFAWIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQD 1078
R S+ K R+S + G+++G G+F VYLA NV T E +A+K + +
Sbjct: 7 RETSLPKERSSPQALILGRYEMGKLLGHGTFAKVYLARNVKTNESVAIKVIDKEKVLKG- 65
Query: 1079 ESAISMVEALKSEVSTLKDLNHVNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRF 1138
++ +K E+S L+ + H NIVQ +EYV GG + + + GR
Sbjct: 66 ----GLIAHIKREISILRRVRHPNIVQLFEVMATKAKIYFVMEYVRGGELFNKVAK-GRL 120
Query: 1139 DDQLIRHLTKQVLEGLAYLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNS 1198
+++ R +Q++ + + H++G+ HRD+K +NLLLD +G K+SDFG+S S+ I +
Sbjct: 121 KEEVARKYFQQLISAVTFCHARGVYHRDLKPENLLLDENGNLKVSDFGLSAVSDQIRQDG 180
Query: 1199 DM-TMRGTVFWMAPEMVDTAHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGK 1257
T GT ++APE++ +AKVDIWS G ++ + AG P+ + V+A +I +
Sbjct: 181 LFHTFCGTPAYVAPEVLARKGYDAAKVDIWSCGVILFVLMAGYLPFHDRNVMAMYKKIYR 240
Query: 1258 SKTAPPIPDDTKDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPFCK 1304
+ P S L + E +PE R T ++ + + K
Sbjct: 241 GEFRCP------RWFSTELTRLLSKLLETNPEKRFTFPEIMENSWFK 281
>At2g34180 [T] KOG0583 Serine/threonine protein kinase
Length = 502
Score = 127 bits (319), Expect = 1e-28
Identities = 99/329 (30%), Positives = 159/329 (48%), Gaps = 23/329 (6%)
Query: 1012 VVEITDKRTISINKSRNSRGEYKEFAWIK---GEIIGKGSFGAVYLALNVTTGEMLAVKQ 1068
V + T+K T + R+ R K G+++G GSF VYLA N+ +GE +A+K
Sbjct: 28 VTKNTNKETSTPESPRSPRTPQGSILMDKYEIGKLLGHGSFAKVYLARNIHSGEDVAIKV 87
Query: 1069 VTVPEFSSQDESAISMVEALKSEVSTLKDLNHVNIVQYLG-FEEKNGIYSLFLEYVAGGS 1127
+ + + +K E+S L+ + H IV L K IY + +EYV GG
Sbjct: 88 IDKEKIVKS-----GLAGHIKREISILRRVRHPYIVHLLEVMATKTKIY-IVMEYVRGGE 141
Query: 1128 VGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHSKGILHRDMKADNLLLDNDGVCKISDFGI 1187
+ + + GR + R +Q++ +A+ HS+G+ HRD+K +NLLLD+ G K+SDFG+
Sbjct: 142 LYNTVAR-GRLREGTARRYFQQLISSVAFCHSRGVYHRDLKLENLLLDDKGNVKVSDFGL 200
Query: 1188 SRKSNNIYSNS-DMTMRGTVFWMAPEMVDTAHGY-SAKVDIWSLGCVVLEMFAGKRPWSN 1245
S S + T GT ++APE++ T GY AK DIWS G ++ + AG P+ +
Sbjct: 201 SVVSEQLKQEGICQTFCGTPAYLAPEVL-TRKGYEGAKADIWSCGVILFVLMAGYLPFDD 259
Query: 1246 FEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPFCKT 1305
++ +I K + P SP + + + +P+ R T ++ H + K
Sbjct: 260 KNILVMYTKIYKGQFKCP------KWFSPELARLVTRMLDTNPDTRITIPEIMKHRWFKK 313
Query: 1306 S---SSFDFPKTKLAQFIKSNDKLNSSRL 1331
F KL + ND +SS L
Sbjct: 314 GFKHVKFYIENDKLCREDDDNDDDDSSSL 342
>At5g25110 [T] KOG0583 Serine/threonine protein kinase
Length = 460
Score = 127 bits (318), Expect = 2e-28
Identities = 78/263 (29%), Positives = 136/263 (51%), Gaps = 13/263 (4%)
Query: 1041 GEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNH 1100
G ++GKG+FG VY +TTGE +A+K + + + M+E +K E+S ++ + H
Sbjct: 18 GRLLGKGTFGKVYYGKEITTGESVAIKIINKDQVKRE-----GMMEQIKREISIMRLVRH 72
Query: 1101 VNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHSK 1160
NIV+ +EYV GG + S I + G+ + R +Q++ + + HS+
Sbjct: 73 PNIVELKEVMATKTKIFFIMEYVKGGELFSKI-VKGKLKEDSARKYFQQLISAVDFCHSR 131
Query: 1161 GILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDM-TMRGTVFWMAPEMVDTAHG 1219
G+ HRD+K +NLL+D +G K+SDFG+S I + + T GT ++APE++
Sbjct: 132 GVSHRDLKPENLLVDENGDLKVSDFGLSALPEQILQDGLLHTQCGTPAYVAPEVLRKKGY 191
Query: 1220 YSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQSF 1279
AK DIWS G ++ + AG P+ + ++ +I KS+ P SP +
Sbjct: 192 DGAKGDIWSCGIILYVLLAGFLPFQDENLMKMYRKIFKSEFEYP------PWFSPESKRL 245
Query: 1280 LDQCFEIDPEMRPTADSLVGHPF 1302
+ + +DP R + +++ P+
Sbjct: 246 ISKLLVVDPNKRISIPAIMRTPW 268
>7292249 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 979
Score = 126 bits (317), Expect = 2e-28
Identities = 87/276 (31%), Positives = 137/276 (49%), Gaps = 27/276 (9%)
Query: 1042 EIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDL-NH 1100
E++G G++G VY + TG++ A+K + V E DE E +K E++ LK NH
Sbjct: 36 EVVGNGTYGQVYKGRHTKTGQLAAIKVMDVTE----DEE-----EEIKLEINVLKKYSNH 86
Query: 1101 VNIVQYLGF------EEKNGIYSLFLEYVAGGSVGSLIRMYG--RFDDQLIRHLTKQVLE 1152
NI Y G K+ L +EY GSV L++ ++ I ++ +++L
Sbjct: 87 RNIATYYGAFIKKSPPGKDDQLWLVMEYCGAGSVTDLVKSTKGQSLKEEWIAYICREILR 146
Query: 1153 GLAYLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPE 1212
GL+YLHS ++HRD+K N+LL ++ K+ DFG+S + + + T GT +WMAPE
Sbjct: 147 GLSYLHSNKVIHRDIKGQNVLLTDNAEVKLVDFGVSAQLDRTIGRRN-TFIGTPYWMAPE 205
Query: 1213 MVDTAHG----YSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDT 1268
++ Y + D+WSLG LEM + P + + A+F I + +PP
Sbjct: 206 VIACDENPDATYDNRSDLWSLGITALEMAESQPPLCDLHPMRALFLI--PRNSPPRLKSK 263
Query: 1269 KDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPFCK 1304
K S F+D D RP ++L+ H F K
Sbjct: 264 K--WSKKFHGFIDTVLVKDYHQRPYTENLLKHGFIK 297
>YOR231w [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K)
Length = 508
Score = 126 bits (316), Expect = 3e-28
Identities = 87/279 (31%), Positives = 148/279 (52%), Gaps = 32/279 (11%)
Query: 1043 IIGKGSFGAVYLALNVTTGEMLAVKQV----TVPEFSSQDESAISMVEALKSEVSTLKDL 1098
I+G+G+ G+V ++ A+K + T PE+ Q + + +SE
Sbjct: 226 ILGEGAGGSVSKCKLKNGSKIFALKVINTLNTDPEYQKQIFRELQFNRSFQSEY------ 279
Query: 1099 NHVNIVQYLGF---EEKNGIYSLFLEYVAGGSVGS----LIRMYGRFDDQLIRHLTKQVL 1151
IV+Y G +E + IY + +EY+ G S+ + L+ GR ++++ + + VL
Sbjct: 280 ----IVRYYGMFTDDENSSIY-IAMEYMGGRSLDAIYKNLLERGGRISEKVLGKIAEAVL 334
Query: 1152 EGLAYLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAP 1211
GL+YLH K ++HRD+K N+LL+ +G K+ DFG+S ++ N + T GT F+MAP
Sbjct: 335 RGLSYLHEKKVIHRDIKPQNILLNENGQVKLCDFGVSGEAVNSLAT---TFTGTSFYMAP 391
Query: 1212 EMVDTAHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVA--AMFQI--GKSKTAPPIPDD 1267
E + YS D+WSLG +LE+ GK P S+ ++ A A F++ P + D+
Sbjct: 392 ERIQ-GQPYSVTSDVWSLGLTILEVANGKFPCSSEKMAANIAPFELLMWILTFTPELKDE 450
Query: 1268 TKDLV--SPAGQSFLDQCFEIDPEMRPTADSLVGHPFCK 1304
+ + SP+ +SF+D C + D RP+ ++ HP+ K
Sbjct: 451 PESNIIWSPSFKSFIDYCLKKDSRERPSPRQMINHPWIK 489
>Hs4502803 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 476
Score = 126 bits (316), Expect = 3e-28
Identities = 75/209 (35%), Positives = 114/209 (53%), Gaps = 12/209 (5%)
Query: 1038 WIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKD 1097
W + +G+G++G V LA+N T E +AVK V + + A+ E +K E+ K
Sbjct: 9 WDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDM-------KRAVDCPENIKKEICINKM 61
Query: 1098 LNHVNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYL 1157
LNH N+V++ G + I LFLEY +GG + I + + Q++ G+ YL
Sbjct: 62 LNHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYL 121
Query: 1158 HSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDM---TMRGTVFWMAPEMV 1214
H GI HRD+K +NLLLD KISDFG++ Y+N + M GT+ ++APE++
Sbjct: 122 HGIGITHRDIKPENLLLDERDNLKISDFGLATVFR--YNNRERLLNKMCGTLPYVAPELL 179
Query: 1215 DTAHGYSAKVDIWSLGCVVLEMFAGKRPW 1243
++ VD+WS G V+ M AG+ PW
Sbjct: 180 KRREFHAEPVDVWSCGIVLTAMLAGELPW 208
>At4g10730 [T] KOG0582 Ste20-like serine/threonine protein kinase
Length = 693
Score = 126 bits (316), Expect = 3e-28
Identities = 85/279 (30%), Positives = 145/279 (51%), Gaps = 29/279 (10%)
Query: 1042 EIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHV 1101
E +G G+ V+ A+ + T E++A+K + + +S ++ ++ E T+ ++H
Sbjct: 31 EEVGYGASAVVHRAIYLPTNEVVAIKSLDLDRCNSN-------LDDIRREAQTMTLIDHP 83
Query: 1102 NIVQ-YLGFEEKNGIYSLFLEYVAGGSVGSLIRMY--GRFDDQLIRHLTKQVLEGLAYLH 1158
N+++ + F + ++ + + ++A GS L++ F++ I + K+ L+ L YLH
Sbjct: 84 NVIKSFCSFAVDHHLW-VVMPFMAQGSCLHLMKAAYPDGFEEAAICSMLKETLKALDYLH 142
Query: 1159 SKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDM-----TMRGTVFWMAPEM 1213
+G +HRD+KA N+LLD+ G K+ DFG+S ++ N D T GT WMAPE+
Sbjct: 143 RQGHIHRDVKAGNILLDDTGEIKLGDFGVSA---CLFDNGDRQRARNTFVGTPCWMAPEV 199
Query: 1214 VDTAHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKD--- 1270
+ GY++K DIWS G LE+ G P+S + + + + APP D +D
Sbjct: 200 LQPGSGYNSKADIWSFGITALELAHGHAPFSKYPPMKVLLM--TIQNAPPGLDYDRDKKF 257
Query: 1271 --LVSPAGQSFLD---QCFEIDPEMRPTADSLVGHPFCK 1304
+S QSF + C D RPTA+ L+ H F K
Sbjct: 258 SKKMSSCAQSFKELVALCLVKDQTKRPTAEKLLKHSFFK 296
>At1g18350 [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K)
Length = 307
Score = 126 bits (316), Expect = 3e-28
Identities = 94/283 (33%), Positives = 146/283 (51%), Gaps = 39/283 (13%)
Query: 1040 KGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLN 1099
K ++G+GS G VY + TTGE+ A+K V + + + L E+ L+ +
Sbjct: 47 KLHVLGRGSSGIVYKVHHKTTGEIYALKSVN-------GDMSPAFTRQLAREMEILRRTD 99
Query: 1100 HVNIVQYLGFEEKN--GIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYL 1157
+V+ G EK G S+ +EY+ GG++ SL G ++ + ++Q+L+GL+YL
Sbjct: 100 SPYVVRCQGIFEKPIVGEVSILMEYMDGGNLESL---RGAVTEKQLAGFSRQILKGLSYL 156
Query: 1158 HSKGILHRDMKADNLLLDNDGVCKISDFGISR--KSNNIYSNSDMTMRGTVFWMAPEMVD 1215
HS I+HRD+K NLLL++ KI+DFG+S+ + Y NS + GT +M+PE D
Sbjct: 157 HSLKIVHRDIKPANLLLNSRNEVKIADFGVSKIITRSLDYCNSYV---GTCAYMSPERFD 213
Query: 1216 TAHGYSAKV---DIWSLGCVVLEMFAGKRP---------WSNFEVVAAMFQIGKSKTAPP 1263
+A G ++ V DIWS G ++LE+F G P W+ V G+ AP
Sbjct: 214 SAAGENSDVYAGDIWSFGVMILELFVGHFPLLPQGQRPDWATLMCVVC---FGEPPRAP- 269
Query: 1264 IPDDTKDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPFCKTS 1306
+ S +SF+D C + R TA L+GHPF + S
Sbjct: 270 ------EGCSDEFRSFVDCCLRKESSERWTASQLLGHPFLRES 306
>7291778 [T] KOG0579 Ste20-like serine/threonine protein kinase
Length = 1726
Score = 126 bits (316), Expect = 3e-28
Identities = 87/274 (31%), Positives = 140/274 (50%), Gaps = 20/274 (7%)
Query: 1035 EFAWIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVST 1094
EF + GE+ G G+FG VY A + A K + + + + + E+
Sbjct: 35 EFWEMVGEL-GDGAFGKVYKAQHKEQKRFAAAKMCQLEDEENLSDHMV--------EIDI 85
Query: 1095 LKDLNHVNIVQ-YLGFEEKNGIYSLFLEYVAGGSVGSL-IRMYGRFDDQLIRHLTKQVLE 1152
L ++ H NIV+ Y F + ++ L +EY GG++ S+ + + + I ++ K + E
Sbjct: 86 LSEIKHPNIVELYEAFSIDDKLWML-IEYCDGGALDSIMVELEKPLTEPQIAYVCKHMTE 144
Query: 1153 GLAYLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPE 1212
GL +LH ++HRD+KA N+LL +G K++DFG+S K+ + D T GT +WMAPE
Sbjct: 145 GLTFLHRNKVIHRDLKAGNVLLTMEGGVKLADFGVSAKNKHTMQKHD-TFIGTPYWMAPE 203
Query: 1213 MV----DTAHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDT 1268
+V + Y KVDIWSLG ++E+ + P S + + +I KS+ P +
Sbjct: 204 LVLCETFRDNPYDHKVDIWSLGITLIELAQMEPPNSEMSPMRVLLKIQKSE---PPKLEQ 260
Query: 1269 KDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPF 1302
S FL + DP++RPT D L+ H F
Sbjct: 261 PSRWSKEFNDFLKKSLVKDPQVRPTTDVLMQHAF 294
>CE21615 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 378
Score = 125 bits (315), Expect = 3e-28
Identities = 83/281 (29%), Positives = 154/281 (54%), Gaps = 22/281 (7%)
Query: 1044 IGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHVNI 1103
IG G+ G V++A + +++AVK++ F +Q + E L +E+ +K H N+
Sbjct: 114 IGVGASGTVFVANVAGSTDVVAVKRMA---FKTQPKK-----EMLLTEIKVMKQYRHPNL 165
Query: 1104 VQYLG--FEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHSKG 1161
V Y+ + + ++ + ++Y+ GG++ ++ + D+ I + ++ L+ L +LH
Sbjct: 166 VNYIESYLVDADDLW-VVMDYLEGGNLTDVV-VKTELDEGQIAAVLQECLKALHFLHRHS 223
Query: 1162 ILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVDTAHGYS 1221
I+HRD+K+DN+LL +G K++D G + + T+ GT +WM+PE+++ Y+
Sbjct: 224 IVHRDIKSDNVLLGMNGEVKLTDMGFCAQIQP--GSKRDTVVGTPYWMSPEILNKKQ-YN 280
Query: 1222 AKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQSFLD 1281
KVDIWSLG + LEM G+ P+ + A++ I ++ P I +D +S +FLD
Sbjct: 281 YKVDIWSLGIMALEMIDGEPPYLRETPLKAIYLIAQN-GKPEIKQ--RDRLSSEFNNFLD 337
Query: 1282 QCFEIDPEMRPTADSLVGHPFCKTSSSFDFPKTKLAQFIKS 1322
+C +DP+ R L+ HPF K + P + L +I++
Sbjct: 338 KCLVVDPDQRADTTELLAHPFLKKAK----PLSSLIPYIRA 374
>At1g50230 [R] KOG0597 Serine-threonine protein kinase FUSED
Length = 269
Score = 125 bits (315), Expect = 3e-28
Identities = 83/265 (31%), Positives = 136/265 (51%), Gaps = 19/265 (7%)
Query: 1042 EIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHV 1101
E++G+GSFG VY TG+ +A+K + + +D + +L+ E+ L+ L H
Sbjct: 10 ELVGEGSFGRVYKGRRKYTGQTVAMKFIMKQGKTDKD------IHSLRQEIEILRKLKHE 63
Query: 1102 NIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHSKG 1161
NI++ L E + + E+ A G + ++ ++ ++ + KQ+++ L YLHS
Sbjct: 64 NIIEMLDSFENAREFCVVTEF-AQGELFEILEDDKCLPEEQVQAIAKQLVKALDYLHSNR 122
Query: 1162 ILHRDMKADNLLLDNDGVCKISDFGISR--KSNNIYSNSDMTMRGTVFWMAPEMVDTAHG 1219
I+HRDMK N+L+ V K+ DFG +R +N + S ++GT +MAPE+V
Sbjct: 123 IIHRDMKPQNILIGAGSVVKLCDFGFARAMSTNTVVLRS---IKGTPLYMAPELV-KEQP 178
Query: 1220 YSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQSF 1279
Y VD+WSLG ++ E++ G+ P+ V A + I K P D +S +SF
Sbjct: 179 YDRTVDLWSLGVILYELYVGQPPFYTNSVYALIRHIVKDPVKYP------DEMSTYFESF 232
Query: 1280 LDQCFEIDPEMRPTADSLVGHPFCK 1304
L +P R T +L HPF K
Sbjct: 233 LKGLLNKEPHSRLTWPALREHPFVK 257
>CE23702 [T] KOG4721 Serine/threonine protein kinase contains leucine zipper
domain
Length = 855
Score = 125 bits (314), Expect = 4e-28
Identities = 83/284 (29%), Positives = 140/284 (49%), Gaps = 25/284 (8%)
Query: 1018 KRTISINKSRNSRGEYKEFAWIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQ 1077
K T+ I KS + E A + E +G GS GAV+ +AVK+V
Sbjct: 42 KTTVEIEKSEDELWEIPFDAISELEWLGSGSQGAVFRGQ--LENRTVAVKKVN------- 92
Query: 1078 DESAISMVEALKSEVSTLKDLNHVNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGR 1137
+ ++E+ L+ L H NI+++LG K+ Y + +EY + G + ++++
Sbjct: 93 --------QLKETEIKHLRHLRHQNIIEFLGVCSKSPCYCIVMEYCSKGQLCTVLKSRNT 144
Query: 1138 FDDQLIRHLTKQVLEGLAYLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSN 1197
+L K++ +G+ YLH ++HRD+K+ N+L+ + KI DFG S + S
Sbjct: 145 ITRELFAQWVKEIADGMHYLHQNKVIHRDLKSPNILISAEDSIKICDFGTSHMQKKMDST 204
Query: 1198 SDMTMRGTVFWMAPEMVDTAHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGK 1257
M+ GTV WMAPEM+ + KVD++S G V+ EM + P++N +A +F +G
Sbjct: 205 M-MSFCGTVSWMAPEMI-KKQPCNEKVDVYSFGVVLWEMLTRETPYANIAQMAIIFGVGT 262
Query: 1258 SKTAPPIPDDTKDLVSPAGQSFL-DQCFEIDPEMRPTADSLVGH 1300
+ + P+P++ +P G L QC RP+ + H
Sbjct: 263 NILSLPMPEE-----APKGLVLLIKQCLSQKGRNRPSFSHIRQH 301
>HsM4507279 [D] KOG0580 Serine/threonine protein kinase
Length = 402
Score = 125 bits (313), Expect = 6e-28
Identities = 86/269 (31%), Positives = 138/269 (50%), Gaps = 17/269 (6%)
Query: 1041 GEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNH 1100
G +GKG FG VYLA + +LA+K + F +Q E A + L+ EV L H
Sbjct: 135 GRPLGKGKFGNVYLAREKQSKFILALKVL----FKAQLEKA-GVEHQLRREVEIQSHLRH 189
Query: 1101 VNIVQYLG-FEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHS 1159
NI++ G F + +Y L LEY G+V ++ +FD+Q +L ++ L+Y HS
Sbjct: 190 PNILRLYGYFHDATRVY-LILEYAPLGTVYRELQKLSKFDEQRTANLYNRIANALSYCHS 248
Query: 1160 KGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVDTAHG 1219
K ++HRD+K +NLLL + G KI+DFG S + S+ T+ GT+ ++ PEM++
Sbjct: 249 KRVIHRDIKPENLLLGSAGELKIADFGWSVHAP---SSRRTTLCGTLDYLPPEMIE-GRM 304
Query: 1220 YSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQSF 1279
+ KVD+WSLG + E GK P+ +I + + P D V+ +
Sbjct: 305 HDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFP------DFVTEGARDL 358
Query: 1280 LDQCFEIDPEMRPTADSLVGHPFCKTSSS 1308
+ + + +P RP ++ HP+ +SS
Sbjct: 359 ISRLLKHNPSQRPMLREVLEHPWITANSS 387
>At1g73660 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 1030
Score = 125 bits (313), Expect = 6e-28
Identities = 84/256 (32%), Positives = 134/256 (51%), Gaps = 17/256 (6%)
Query: 1041 GEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNH 1100
GE IG GS+G VY G+ +V V +F QD + ++ E +SEV +K L H
Sbjct: 751 GERIGLGSYGEVY------RGDWHGT-EVAVKKFLDQDLTGEAL-EEFRSEVRIMKKLRH 802
Query: 1101 VNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLI-RMYGRFDDQLIRHLTKQVLEGLAYLHS 1159
NIV ++G + S+ E++ GS+ LI R + D++ + G+ YLHS
Sbjct: 803 PNIVLFMGAVTRPPNLSIVTEFLPRGSLYRLIHRPNNQLDERRRLRMALDAARGMNYLHS 862
Query: 1160 KG--ILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVDTA 1217
I+HRD+K+ NLL+D + V K+ DFG+SR ++ Y +S T GT WMAPE++
Sbjct: 863 CNPMIVHRDLKSPNLLVDKNWVVKVCDFGLSRMKHSTYLSSKST-AGTAEWMAPEVLRNE 921
Query: 1218 HGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQ 1277
K D++S G ++ E+F ++PW + + +G IP D V PA
Sbjct: 922 PA-DEKCDVYSYGVILWELFTLQQPWGKMNPMQVVGAVGFQHRRLDIP----DFVDPAIA 976
Query: 1278 SFLDQCFEIDPEMRPT 1293
+ +C++ D ++RP+
Sbjct: 977 DLISKCWQTDSKLRPS 992
>At1g51660 [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K)
Length = 366
Score = 125 bits (313), Expect = 6e-28
Identities = 94/319 (29%), Positives = 162/319 (50%), Gaps = 42/319 (13%)
Query: 1028 NSRGEYKEFA-WIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVE 1086
NS E K ++ ++G IG G+ G VY ++ + + A+K + + + +E+ +
Sbjct: 68 NSSIEAKNYSDLVRGNRIGSGAGGTVYKVIHRPSSRLYALKVI----YGNHEETVRRQI- 122
Query: 1087 ALKSEVSTLKDLNHVNIVQYLGFEEKNGIYSLFLEYVAGGSV-GSLIRMYGRFDDQLIRH 1145
E+ L+D+NH N+V+ ++NG + LE++ GS+ G+ + + +Q +
Sbjct: 123 --CREIEILRDVNHPNVVKCHEMFDQNGEIQVLLEFMDKGSLEGAHV-----WKEQQLAD 175
Query: 1146 LTKQVLEGLAYLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGT 1205
L++Q+L GLAYLHS+ I+HRD+K NLL+++ KI+DFG+SR + ++ GT
Sbjct: 176 LSRQILSGLAYLHSRHIVHRDIKPSNLLINSAKNVKIADFGVSRILAQTMDPCNSSV-GT 234
Query: 1206 VFWMAPEMVDT------AHGYSAKVDIWSLGCVVLEMFAGKRP--------WSNFEVVAA 1251
+ +M+PE ++T GY+ DIWSLG +LE + G+ P W++
Sbjct: 235 IAYMSPERINTDLNQGKYDGYAG--DIWSLGVSILEFYLGRFPFPVSRQGDWASLMCAIC 292
Query: 1252 MFQIGKSKTAPPIPDDTKDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPF-CKTSSSFD 1310
M Q P + SP + F+ C + +P R +A L+ HPF + S S +
Sbjct: 293 MSQ----------PPEAPATASPEFRHFISCCLQREPGKRRSAMQLLQHPFILRASPSQN 342
Query: 1311 FPKTKLAQFIKSNDKLNSS 1329
L Q + L+SS
Sbjct: 343 RSPQNLHQLLPPPRPLSSS 361
>Hs6005810 [T] KOG0576 Mitogen-activated protein kinase kinase kinase kinase
(MAP4K) germinal center kinase family
Length = 833
Score = 124 bits (312), Expect = 8e-28
Identities = 79/259 (30%), Positives = 137/259 (52%), Gaps = 12/259 (4%)
Query: 1044 IGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHVNI 1103
+G G++G V+ A + +G+++A+K V + D+ V L+ E+ LK H NI
Sbjct: 23 LGGGTYGEVFKARDKVSGDLVALKMV---KMEPDDD-----VSTLQKEILILKTCRHANI 74
Query: 1104 VQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHSKGIL 1163
V Y G + +E+ GS+ + ++ G + I ++ ++VL+GLAYLHS+ +
Sbjct: 75 VAYHGSYLWLQKLWICMEFCGAGSLQDIYQVTGSLSELQISYVCREVLQGLAYLHSQKKI 134
Query: 1164 HRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVDTA--HGYS 1221
HRD+K N+L+++ G +++DFGIS + + ++ GT +WMAPE+ A GY+
Sbjct: 135 HRDIKGANILINDAGEVRLADFGISAQIGATLARR-LSFIGTPYWMAPEVAAVALKGGYN 193
Query: 1222 AKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQSFLD 1281
DIWSLG +E+ + P + + +F + KS PP + K S A +F+
Sbjct: 194 ELCDIWSLGITAIELAELQPPLFDVHPLRVLFLMTKSGYQPPRLKE-KGKWSAAFHNFIK 252
Query: 1282 QCFEIDPEMRPTADSLVGH 1300
P+ RP+A ++ H
Sbjct: 253 VTLTKSPKKRPSATKMLSH 271
>At4g14480 [T] KOG0582 Ste20-like serine/threonine protein kinase
Length = 487
Score = 124 bits (312), Expect = 8e-28
Identities = 87/290 (30%), Positives = 142/290 (48%), Gaps = 31/290 (10%)
Query: 1044 IGKGSFGAVYLALNVTTGEML-AVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHVN 1102
IG G +VY A+ + M+ A+K + + + + +S L+ E T+ L+H N
Sbjct: 21 IGVGVSASVYKAICIPMNSMVVAIKAIDLDQSRADFDS-------LRRETKTMSLLSHPN 73
Query: 1103 IVQ-YLGFEEKNGIYSLFLEYVAGGSVGSLIRMY--GRFDDQLIRHLTKQVLEGLAYLHS 1159
I+ Y F ++ + + +++ GS+ S++ + I K+ L ++YLH
Sbjct: 74 ILNAYCSFTVDRCLW-VVMPFMSCGSLHSIVSSSFPSGLPENCISVFLKETLNAISYLHD 132
Query: 1160 KGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMT---------MRGTVFWMA 1210
+G LHRD+KA N+L+D+DG K++DFG+S ++S T + GT +WMA
Sbjct: 133 QGHLHRDIKAGNILVDSDGSVKLADFGVSASIYEPVTSSSGTTSSSLRLTDIAGTPYWMA 192
Query: 1211 PEMVDTAHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAM---------FQIGKSKTA 1261
PE+V + GY K DIWS G LE+ G+ P S+ + ++ F + T+
Sbjct: 193 PEVVHSHTGYGFKADIWSFGITALELAHGRPPLSHLPPLKSLLMKITKRFHFSDYEINTS 252
Query: 1262 PPIPDDTKDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPFCKTSSSFDF 1311
K S A + + C E DP RP+A+ L+ HPF K DF
Sbjct: 253 GSSKKGNKKF-SKAFREMVGLCLEQDPTKRPSAEKLLKHPFFKNCKGLDF 301
>CE26212 [T] KOG0582 Ste20-like serine/threonine protein kinase
Length = 545
Score = 124 bits (311), Expect = 1e-27
Identities = 85/283 (30%), Positives = 132/283 (46%), Gaps = 27/283 (9%)
Query: 1042 EIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHV 1101
E IG G+ V+ A + E +A+K + + E + V+ L E+ + NH
Sbjct: 61 ESIGVGATATVFTAYCLPRNEKVAIKCINL-------EKCQTSVDELSHEIQAMSQCNHP 113
Query: 1102 NIVQYL-GFEEKNGIYSLFLEYVAGGSVGSLIR----------MYGRFDDQLIRHLTKQV 1150
N+V Y F + ++ + G + L R +G D+ I + ++V
Sbjct: 114 NVVSYYTSFIAQEELWVVMRLLNCGSMLDILKRKVKAIGKEQAQFGVLDEVSIATVLREV 173
Query: 1151 LEGLAYLHSKGILHRDMKADNLLLDNDGVCKISDFGIS---RKSNNIYSNSDM--TMRGT 1205
L+GL Y H G +HRD+KA N+LL +DG +I+DFG+S S S + T GT
Sbjct: 174 LKGLEYFHLNGQIHRDIKAGNILLADDGTIQIADFGVSGWLASSGGDLSRQKVRHTFVGT 233
Query: 1206 VFWMAPEMVDTAHGYSAKVDIWSLGCVVLEMFAGKRPWSNF-EVVAAMFQIGKSKTAPPI 1264
WMAPE+++ GY K DIWSLG + +E+ G P+ + + M +
Sbjct: 234 PCWMAPEVMEQVQGYDFKADIWSLGILAIELATGTAPYHKYPPMKVLMLTLQNDPPTLET 293
Query: 1265 PDDTKDLVSPAGQSF---LDQCFEIDPEMRPTADSLVGHPFCK 1304
+ KD G+SF + C + DP RPTA L+ + F K
Sbjct: 294 NAERKDQYKAYGKSFKTLIRDCLQKDPAKRPTASELLKYSFFK 336
>At5g50860 [D] KOG0600 Cdc2-related protein kinase
Length = 580
Score = 124 bits (311), Expect = 1e-27
Identities = 95/325 (29%), Positives = 155/325 (47%), Gaps = 43/325 (13%)
Query: 1040 KGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLN 1099
K E IG+G++ VY A ++ +G+++A+K+V ++ V+ + E+ L+ LN
Sbjct: 116 KLEKIGQGTYSNVYKAKDLLSGKIVALKKVRFDNLEAES------VKFMAREILVLRRLN 169
Query: 1100 HVNIVQYLGFEEKNGIYSLFL--EYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYL 1157
H N+++ G SL+L EY+ G +FD ++ KQ+L GL +
Sbjct: 170 HPNVIKLQGLVTSRVSCSLYLVFEYMEHDLSGLAATQGLKFDLPQVKCFMKQLLSGLEHC 229
Query: 1158 HSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVDTA 1217
HS+G+LHRD+K NLL+DNDG+ KI+DFG++ + + + T+++ PE++ A
Sbjct: 230 HSRGVLHRDIKGSNLLIDNDGILKIADFGLATFYDPKQKQTMTSRVVTLWYRPPELLLGA 289
Query: 1218 HGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPP--------IPDDT- 1268
Y VD+WS GC++ E+ AGK V + +I K +P +P+ T
Sbjct: 290 TSYGTGVDLWSAGCIMAELLAGKPVMPGRTEVEQLHKIFKLCGSPSDSYWKKYRLPNATL 349
Query: 1269 -------KDLVSPAGQSF-------LDQCFEIDPEMRPTADSLVGHPF-------CKTSS 1307
K V+ A F ++ IDP R T+ S + F C SS
Sbjct: 350 FKPQHPYKRCVAEAFNGFTPSSVHLVETLLTIDPADRGTSTSALNSEFFTTEPLPCDPSS 409
Query: 1308 SFDFPKTKLAQFIKSNDKLNSSRLR 1332
+P +K + N KL LR
Sbjct: 410 LPKYPPSK-----ELNVKLRDEELR 429
>At4g24100 [T] KOG0582 Ste20-like serine/threonine protein kinase
Length = 710
Score = 124 bits (311), Expect = 1e-27
Identities = 84/275 (30%), Positives = 143/275 (51%), Gaps = 29/275 (10%)
Query: 1042 EIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHV 1101
E IG G+ VY A+ + T E++A+K + + +S ++ ++ E T+ ++H
Sbjct: 37 EEIGHGASAVVYRAIYLPTNEVVAIKCLDLDRCNSN-------LDDIRRESQTMSLIDHP 89
Query: 1102 NIVQ-YLGFEEKNGIYSLFLEYVAGGSVGSLIRMY--GRFDDQLIRHLTKQVLEGLAYLH 1158
N+++ + F + ++ + + ++A GS L++ F++ I + K+ L+ L YLH
Sbjct: 90 NVIKSFCSFSVDHSLW-VVMPFMAQGSCLHLMKTAYSDGFEESAICCVLKETLKALDYLH 148
Query: 1159 SKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDM-----TMRGTVFWMAPEM 1213
+G +HRD+KA N+LLD++G K+ DFG+S ++ N D T GT WMAPE+
Sbjct: 149 RQGHIHRDVKAGNILLDDNGEIKLGDFGVSA---CLFDNGDRQRARNTFVGTPCWMAPEV 205
Query: 1214 VDTAHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKD--- 1270
+ +GY++K DIWS G LE+ G P+S + + + + APP D +D
Sbjct: 206 LQPGNGYNSKADIWSFGITALELAHGHAPFSKYPPMKVLLM--TIQNAPPGLDYDRDKKF 263
Query: 1271 --LVSPAGQSFLD---QCFEIDPEMRPTADSLVGH 1300
QSF + C D RPTA+ L+ H
Sbjct: 264 SKRTFSCAQSFKEMVAMCLVKDQTKRPTAEKLLKH 298
>At1g74330 [D] KOG0600 Cdc2-related protein kinase
Length = 445
Score = 124 bits (311), Expect = 1e-27
Identities = 96/314 (30%), Positives = 148/314 (46%), Gaps = 42/314 (13%)
Query: 1037 AWIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLK 1096
A+ K E IG+G++ V+ A+ TG ++A+K+V F + V+ + E+ L+
Sbjct: 120 AFEKLEKIGQGTYSNVFRAVETETGRIVALKKVRFDNFEPES------VKFMAREILILR 173
Query: 1097 DLNHVNIVQYLGF--EEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGL 1154
LNH NI++ G + + L EY+ G L +F I+ KQ+L GL
Sbjct: 174 RLNHPNIIKLEGLITSKLSCNIQLVFEYMEHDLTGLLSSPDIKFTTPQIKCYMKQLLSGL 233
Query: 1155 AYLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNI-YSNSDMTMRGTVFW-MAPE 1212
+ HS+G++HRD+K NLLL N+G+ K++DFG++ SN+ + +T R W PE
Sbjct: 234 DHCHSRGVMHRDIKGSNLLLSNEGILKVADFGLANFSNSSGHKKKPLTSRVVTLWYRPPE 293
Query: 1213 MVDTAHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPP--------- 1263
++ A Y A VD+WS+GCV E+ GK V + +I K +PP
Sbjct: 294 LLLGATDYGASVDLWSVGCVFAELLLGKPILRGRTEVEQLHKIFKLCGSPPEDYWKKSKL 353
Query: 1264 ---------------IPDDTKDLVSPAGQSFLDQCFEIDPEMRPTADS-LVGHPF----- 1302
+ + KDL S + ++ IDP R TA S LV F
Sbjct: 354 PHAMLFKPQQTYDSCLRETLKDL-SETEINLIETLLSIDPHKRGTASSALVSQYFTTKPF 412
Query: 1303 -CKTSSSFDFPKTK 1315
C SS +P +K
Sbjct: 413 ACDPSSLPIYPPSK 426
>At2g45490 [D] KOG0580 Serine/threonine protein kinase
Length = 288
Score = 124 bits (310), Expect = 1e-27
Identities = 85/263 (32%), Positives = 132/263 (49%), Gaps = 16/263 (6%)
Query: 1041 GEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNH 1100
G +GKG FG VYLA + ++A+K + F Q E + L+ E+ L H
Sbjct: 25 GRPLGKGKFGRVYLAREAKSKYIVALKVI----FKEQIEK-YKIHHQLRREMEIQTSLRH 79
Query: 1101 VNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHSK 1160
NI++ G+ N L LEY GG + +++ G +Q + + LAY H K
Sbjct: 80 PNILRLFGWFHDNERIFLILEYAHGGELYGVLKQNGHLTEQQAATYIASLSQALAYCHGK 139
Query: 1161 GILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVDTA-HG 1219
++HRD+K +NLLLD++G KI+DFG S +S SN TM GT+ ++APEMV+ H
Sbjct: 140 CVIHRDIKPENLLLDHEGRLKIADFGWSVQS----SNKRKTMCGTLDYLAPEMVENRDHD 195
Query: 1220 YSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQSF 1279
Y+ VD W+LG + E G P+ +I K + P+ + VS ++
Sbjct: 196 YA--VDNWTLGILCYEFLYGNPPFEAESQKDTFKRILKIDLSFPLTPN----VSEEAKNL 249
Query: 1280 LDQCFEIDPEMRPTADSLVGHPF 1302
+ Q DP R + + ++ HP+
Sbjct: 250 ISQLLVKDPSKRLSIEKIMQHPW 272
>At1g05100 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 339
Score = 124 bits (310), Expect = 1e-27
Identities = 91/281 (32%), Positives = 141/281 (49%), Gaps = 37/281 (13%)
Query: 1038 WIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKD 1097
W +G+ +G+GS V A +GE LAVK EF E L+ E L
Sbjct: 3 WTRGKTLGRGSTATVSAATCHESGETLAVKSA---EFHRS--------EFLQREAKILSS 51
Query: 1098 LNHVNIVQYLGFE------EKNG---IYSLFLEYVAGGSVGSLIRMYGRF-DDQLIRHLT 1147
LN ++ Y G E NG YSL +EY G++ + G F D+ + T
Sbjct: 52 LNSPYVIGYRGCEITREPFHNNGEATTYSLLMEYAPYGTLTDVATKNGGFIDEARVVKYT 111
Query: 1148 KQVLEGLAYLH-SKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMT--MRG 1204
+Q+L GL Y+H SKGI H D+K N+L+ +G KI+DFG ++ + ++T +RG
Sbjct: 112 RQILLGLEYIHNSKGIAHCDIKGSNVLVGENGEAKIADFGCAK-----WVEPEITEPVRG 166
Query: 1205 TVFWMAPEMVDTAHGYSAKVDIWSLGCVVLEMFAGKRPW--SNF-EVVAAMFQIGKSKTA 1261
T +MAPE + DIW++GC V+EM G +PW ++F + V+ ++++G
Sbjct: 167 TPAFMAPEAA-RGERQGKESDIWAVGCTVIEMVTGSQPWIGADFTDPVSVLYRVGYLGEL 225
Query: 1262 PPIPDDTKDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPF 1302
P +P ++ + FL +C + + R TA L+ HPF
Sbjct: 226 PELPCS----LTEQAKDFLGKCLKKEATERWTASQLLNHPF 262
>At1g01140 [T] KOG0583 Serine/threonine protein kinase
Length = 447
Score = 124 bits (310), Expect = 1e-27
Identities = 79/240 (32%), Positives = 125/240 (51%), Gaps = 13/240 (5%)
Query: 1026 SRNSRGEYKEFAWIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMV 1085
SR G Y+ G +G+GSF V A N TG+ A+K + + MV
Sbjct: 12 SRTRVGNYE-----MGRTLGEGSFAKVKYAKNTVTGDQAAIKILDREKVFRH-----KMV 61
Query: 1086 EALKSEVSTLKDLNHVNIVQYLG-FEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIR 1144
E LK E+ST+K + H N+V+ + K IY + LE V GG + I GR + R
Sbjct: 62 EQLKREISTMKLIKHPNVVEIIEVMASKTKIY-IVLELVNGGELFDKIAQQGRLKEDEAR 120
Query: 1145 HLTKQVLEGLAYLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDM-TMR 1203
+Q++ + Y HS+G+ HRD+K +NL+LD +GV K+SDFG+S S + + + T
Sbjct: 121 RYFQQLINAVDYCHSRGVYHRDLKPENLILDANGVLKVSDFGLSAFSRQVREDGLLHTAC 180
Query: 1204 GTVFWMAPEMVDTAHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPP 1263
GT ++APE++ A D+WS G ++ + AG P+ ++ +I K++ + P
Sbjct: 181 GTPNYVAPEVLSDKGYDGAAADVWSCGVILFVLMAGYLPFDEPNLMTLYKRICKAEFSCP 240
>YNL298w [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 842
Score = 123 bits (309), Expect = 2e-27
Identities = 85/280 (30%), Positives = 142/280 (50%), Gaps = 24/280 (8%)
Query: 1042 EIIGKGSFGAVYLALNV---TTGEMLAVKQVTVPEFSSQDESAISMV--------EALKS 1090
E G+G+ G+VYLA T M+ + + E D+ AI + E + +
Sbjct: 550 EKAGQGASGSVYLAERTHIPTESNMIELINNDIDEPHVGDKVAIKQMVLSKQPRKELIVN 609
Query: 1091 EVSTLKDLNHVNIVQYL-GFEEKNGIYSLFLEYVAGGSVGSLIR-------MYGRFDDQL 1142
E+ +KD H NIV +L + + + +E++ GGS+ +I + +
Sbjct: 610 EILVMKDSRHKNIVNFLEAYLRTDDDLWVVMEFMEGGSLTDIIENSPTNDNSHSPLTEPQ 669
Query: 1143 IRHLTKQVLEGLAYLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTM 1202
I ++ ++ +GL +LH K I+HRD+K+DN+LLD KI+DFG + + S TM
Sbjct: 670 IAYIVRETCQGLKFLHDKHIIHRDIKSDNVLLDTRARVKITDFGFCARLTDKRSKR-ATM 728
Query: 1203 RGTVFWMAPEMVDTAHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAP 1262
GT +WMAPE+V Y K+D+WSLG + +EM G+ P+ N + + A++ I + T P
Sbjct: 729 VGTPYWMAPEVVKQRE-YDEKIDVWSLGIMTIEMLEGEPPYLNEDPLKALYLIATNGT-P 786
Query: 1263 PIPDDTKDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPF 1302
+ + +S + FL C +D R + + L+ H F
Sbjct: 787 KLKH--PESLSLEIKRFLSVCLCVDVRYRASTEELLHHGF 824
>Hs4507275 [D] KOG0580 Serine/threonine protein kinase
Length = 403
Score = 123 bits (309), Expect = 2e-27
Identities = 89/289 (30%), Positives = 146/289 (49%), Gaps = 20/289 (6%)
Query: 1024 NKSRNSRGEYKEFAWIKGEI---IGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDES 1080
+K +N + +++A EI +GKG FG VYLA + +LA+K + F +Q E
Sbjct: 116 SKQKNEESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVL----FKAQLEK 171
Query: 1081 AISMVEALKSEVSTLKDLNHVNIVQYLG-FEEKNGIYSLFLEYVAGGSVGSLIRMYGRFD 1139
A + L+ EV L H NI++ G F + +Y L LEY G+V ++ +FD
Sbjct: 172 A-GVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVY-LILEYAPLGTVYRELQKLSKFD 229
Query: 1140 DQLIRHLTKQVLEGLAYLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSD 1199
+Q ++ L+Y HSK ++HRD+K +NLLL + G KI+DFG S + S+
Sbjct: 230 EQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAP---SSRR 286
Query: 1200 MTMRGTVFWMAPEMVDTAHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSK 1259
T+ GT+ ++ PEM++ + KVD+WSLG + E GK P+ +I + +
Sbjct: 287 TTLCGTLDYLPPEMIE-GRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVE 345
Query: 1260 TAPPIPDDTKDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPFCKTSSS 1308
P D V+ + + + + +P RP ++ HP+ +SS
Sbjct: 346 FTFP------DFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSS 388
>At3g45670 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 379
Score = 123 bits (309), Expect = 2e-27
Identities = 107/362 (29%), Positives = 164/362 (44%), Gaps = 55/362 (15%)
Query: 970 KSLKPPKRTKTIRIIAQEASEARKNEVSQKLQRKNTKMWGTKVVEITDKRTISINKSRNS 1029
K++K KRT+T + +K +S ++ + G + K + ++ +
Sbjct: 43 KNIKKKKRTRT-------PLKKKKKSISSSVE----SIIGVSFKSASQKHSTTVTRDG-- 89
Query: 1030 RGEYKEFAWIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALK 1089
G K +W+K ++G+G++G VYLA T + + E AI + LK
Sbjct: 90 -GVKKISSWVKSRLLGEGAYGCVYLA--------------TSKDDIYKTERAIKSADVLK 134
Query: 1090 S-----EVSTLKDLNHVNIVQYLGFE---EKNGI-YSLFLEYVAGGSVGSLIR-MYGRFD 1139
+ E L+ L +++ G E E G Y+L LEY +G + +I G
Sbjct: 135 AWSLMHEGRILRSLQSPFVIRCYGHEIAREGTGHQYNLILEYCSGQCLADMIEDNQGGIP 194
Query: 1140 DQLIRHLTKQVLEGLAYLHSKGILHRDMKADNLLL--------DNDGVCKISDFGIS-RK 1190
+ ++ VL GL+Y+H + I+H ++K DNLLL N + KI+DFG+S K
Sbjct: 195 EFDVKQFAIDVLSGLSYIHRRNIIHCEIKPDNLLLSPVDHRFRSNGFLTKIADFGLSMEK 254
Query: 1191 SNNIYSNSDMTMRGTVFWMAPEMVDTAHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVA 1250
+ Y N MRGT +MAPE++ VDI + GC VLEM GKR W + +A
Sbjct: 255 GSKEYGNGRGHMRGTTRYMAPELIGGGL-LDFAVDICAFGCSVLEMLTGKRVWGEYGDLA 313
Query: 1251 A---MFQIGKSKTAPPIPDDTKDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPFCKTSS 1307
+ IG S P I +S Q FL +C +P R T LV HPF +
Sbjct: 314 HDDWVDLIGHSDLTPQI----SIRLSAEAQDFLMRCLVKEPGSRWTIGELVDHPFLCSDE 369
Query: 1308 SF 1309
F
Sbjct: 370 EF 371
>At1g04700_2 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 333
Score = 123 bits (309), Expect = 2e-27
Identities = 87/301 (28%), Positives = 148/301 (48%), Gaps = 36/301 (11%)
Query: 1025 KSRNSRGEYKEFAWIKGEI------------------IGKGSFGAVYLALNVTTGEMLAV 1066
KSRN+ + E A ++ E +G G+FG VY G +A+
Sbjct: 26 KSRNTDDSFSEAAMVEIEAGIYGLQIIKNTDLEDLHELGSGTFGTVYYGK--WRGTDVAI 83
Query: 1067 KQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHVNIVQYLGF--EEKNGIYSLFLEYVA 1124
K++ FS + E L +L+H N+V + G + G + EY+
Sbjct: 84 KRIKNSCFSGGSSEQARQTKDFWREARILANLHHPNVVAFYGVVPDGPGGTMATVTEYMV 143
Query: 1125 GGSVGSLIRMYGRFDDQLIR-HLTKQVLEGLAYLHSKGILHRDMKADNLLLD----NDGV 1179
GS+ +++ R D+ + +T G+ YLH K I+H D+K DNLL++ +
Sbjct: 144 NGSLRHVLQRKDRLLDRRKKLMITLDSAFGMEYLHMKNIVHFDLKCDNLLVNLRDPQRPI 203
Query: 1180 CKISDFGISR-KSNNIYSNSDMTMRGTVFWMAPEMVD-TAHGYSAKVDIWSLGCVVLEMF 1237
CK+ DFG+SR K N + S +RGT+ WMAPE+++ +++ S KVD++S G V+ E+
Sbjct: 204 CKVGDFGLSRIKRNTLVSGG---VRGTLPWMAPELLNGSSNRVSEKVDVFSFGIVMWEIL 260
Query: 1238 AGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQSFLDQCFEIDPEMRPTADSL 1297
G+ P++N A + I + PP+P+ + + ++QC+ DP +RP+ +
Sbjct: 261 TGEEPYANLHCGAIIGGIVNNTLRPPVPERCE----AEWRKLMEQCWSFDPGVRPSFTEI 316
Query: 1298 V 1298
V
Sbjct: 317 V 317
>Hs16936528 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 298
Score = 123 bits (308), Expect = 2e-27
Identities = 92/296 (31%), Positives = 146/296 (49%), Gaps = 49/296 (16%)
Query: 1040 KGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLN 1099
K E IG+G++G VY A N TGE++A+K++ + D + E+S LK+LN
Sbjct: 6 KVEKIGEGTYGVVYKARNKLTGEVVALKKIRL------DTETEGVPSTAIREISLLKELN 59
Query: 1100 HVNIVQYLG-FEEKNGIYSLF------LEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLE 1152
H NIV+ L +N +Y +F L+ S + I + LI+ Q+L+
Sbjct: 60 HPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPL------PLIKSYLFQLLQ 113
Query: 1153 GLAYLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSN---NIYSNSDMTMRGTVFWM 1209
GLA+ HS +LHRD+K NLL++ +G K++DFG++R Y++ +T+ ++
Sbjct: 114 GLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTL----WYR 169
Query: 1210 APEMVDTAHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAP------- 1262
APE++ YS VDIWSLGC+ EM + + + +F+I ++ P
Sbjct: 170 APEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPG 229
Query: 1263 --PIPD-----------DTKDLVSPA---GQSFLDQCFEIDPEMRPTADSLVGHPF 1302
+PD D +V P G+S L Q DP R +A + + HPF
Sbjct: 230 VTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPF 285
>CE27768 [R] KOG0586 Serine/threonine protein kinase
Length = 1096
Score = 123 bits (308), Expect = 2e-27
Identities = 82/257 (31%), Positives = 133/257 (50%), Gaps = 18/257 (7%)
Query: 1044 IGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAI--SMVEALKSEVSTLKDLNHV 1101
IGKG+F V LA +V TG +A+K + D++A+ S ++ L EV +K L+H
Sbjct: 128 IGKGNFAKVKLAKHVITGHEVAIKII--------DKTALNPSSLQKLFREVKIMKQLDHP 179
Query: 1102 NIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHSKG 1161
NIV+ E L LEY +GG V + +GR ++ R +Q++ + YLHSK
Sbjct: 180 NIVKLYQVMETEQTLYLVLEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYLHSKN 239
Query: 1162 ILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVDTAHGYS 1221
I+HRD+KA+NLLLD D KI+DFG S + N T G+ + APE+
Sbjct: 240 IIHRDLKAENLLLDQDMNIKIADFGFSNTFS--LGNKLDTFCGSPPYAAPELFSGKKYDG 297
Query: 1222 AKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQSFLD 1281
+VD+WSLG ++ + +G P+ + ++ + K P +S ++ L
Sbjct: 298 PEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPF------YMSTDCENLLK 351
Query: 1282 QCFEIDPEMRPTADSLV 1298
+ I+P+ R + D+++
Sbjct: 352 KFLVINPQRRSSLDNIM 368
>CE23838 [R] KOG0586 Serine/threonine protein kinase
Length = 1192
Score = 123 bits (308), Expect = 2e-27
Identities = 82/257 (31%), Positives = 133/257 (50%), Gaps = 18/257 (7%)
Query: 1044 IGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAI--SMVEALKSEVSTLKDLNHV 1101
IGKG+F V LA +V TG +A+K + D++A+ S ++ L EV +K L+H
Sbjct: 176 IGKGNFAKVKLAKHVITGHEVAIKII--------DKTALNPSSLQKLFREVKIMKQLDHP 227
Query: 1102 NIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHSKG 1161
NIV+ E L LEY +GG V + +GR ++ R +Q++ + YLHSK
Sbjct: 228 NIVKLYQVMETEQTLYLVLEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYLHSKN 287
Query: 1162 ILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVDTAHGYS 1221
I+HRD+KA+NLLLD D KI+DFG S + N T G+ + APE+
Sbjct: 288 IIHRDLKAENLLLDQDMNIKIADFGFSNTFS--LGNKLDTFCGSPPYAAPELFSGKKYDG 345
Query: 1222 AKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQSFLD 1281
+VD+WSLG ++ + +G P+ + ++ + K P +S ++ L
Sbjct: 346 PEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPF------YMSTDCENLLK 399
Query: 1282 QCFEIDPEMRPTADSLV 1298
+ I+P+ R + D+++
Sbjct: 400 KFLVINPQRRSSLDNIM 416
>At5g45810 [T] KOG0583 Serine/threonine protein kinase
Length = 483
Score = 123 bits (308), Expect = 2e-27
Identities = 70/211 (33%), Positives = 116/211 (54%), Gaps = 7/211 (3%)
Query: 1041 GEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNH 1100
G ++G G+F VYLA N +GE +A+K + + ++ +K E+S L+ + H
Sbjct: 31 GRLLGHGTFAKVYLARNAQSGESVAIKVIDKEKVLKS-----GLIAHIKREISILRRVRH 85
Query: 1101 VNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHSK 1160
NIVQ +EYV GG + + + GR +++ R +Q++ +++ H +
Sbjct: 86 PNIVQLFEVMATKSKIYFVMEYVKGGELFNKVAK-GRLKEEMARKYFQQLISAVSFCHFR 144
Query: 1161 GILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDM-TMRGTVFWMAPEMVDTAHG 1219
G+ HRD+K +NLLLD +G K+SDFG+S S+ I + T GT ++APE++
Sbjct: 145 GVYHRDLKPENLLLDENGNLKVSDFGLSAVSDQIRQDGLFHTFCGTPAYVAPEVLARKGY 204
Query: 1220 YSAKVDIWSLGCVVLEMFAGKRPWSNFEVVA 1250
AKVDIWS G ++ + AG P+ + V+A
Sbjct: 205 DGAKVDIWSCGVILFVLMAGFLPFHDRNVMA 235
>At3g46140 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 376
Score = 123 bits (308), Expect = 2e-27
Identities = 93/299 (31%), Positives = 144/299 (48%), Gaps = 42/299 (14%)
Query: 1034 KEFAWIKGEIIGKGSFGAVYLALN--VTTGEMLAVKQVTVPEFSSQDESAISMVEALKSE 1091
K +WIK E +G+GS+G+VYLA + T +A+K + IS +L E
Sbjct: 92 KSSSWIKSEFLGRGSYGSVYLATSKKAKTKTTMAIK-----------SAEISRASSLMDE 140
Query: 1092 VSTLKDLNHVNIVQYLG---------FEEKNGIYSLFLEYVAGGSVGSLIR-MYGRFDDQ 1141
L L+ IV+ G F + Y+L LEY +G S+ L+ G ++
Sbjct: 141 ERILTRLSSPFIVRCYGHEIAREETLFGGERTNYNLILEYCSGKSLFDLVNDNLGGLSEK 200
Query: 1142 LIRHLTKQVLEGLAYLHSKGILHRDMKADNLLL--------DNDGVCKISDFGIS-RKSN 1192
++ L + +L GL +H I+H D+K +N+ L + V KI DFG++ K +
Sbjct: 201 DVKLLARDILYGLDCIHRANIIHCDIKPENIFLTPVENRIRPSGYVAKIGDFGLALEKGS 260
Query: 1193 NIYSNSDMTMRGTVFWMAPEMVDTAHG-YSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAA 1251
+ Y + RGT +M+PE++ HG VD W+ GC VLEM G++ W + +
Sbjct: 261 SEYEKASGHRRGTTRYMSPELI--RHGIVDYAVDTWAFGCTVLEMLTGQQVWGEHSDLGS 318
Query: 1252 M---FQIGKSKTAPPIPDDTKDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPFCKTSS 1307
+ IG+S P IP D +S Q FL +C + DP R +L+ HPF + S
Sbjct: 319 VDWDILIGQSCYIPYIP----DWLSEEAQHFLSRCLKRDPASRWGIGALLNHPFLQCGS 373
>At2g41930 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 351
Score = 123 bits (308), Expect = 2e-27
Identities = 87/276 (31%), Positives = 142/276 (50%), Gaps = 24/276 (8%)
Query: 1042 EIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVS---TLKDL 1098
+++GKG++G+V L + L V + + S++ +I + SE+ + L
Sbjct: 9 KVLGKGTYGSVELFSHKQNDGSLLYNAVKIMD--SENYGSIDQEFRILSELRGCPCIVQL 66
Query: 1099 NHVNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLI-RMYGRFDDQLIRHLTKQVLEGLAYL 1157
++VQ + K +Y + +EY A G++ + I R + D +I+ T+ +L+GL +
Sbjct: 67 CGNSLVQGIDCNGKK-VYMMSMEYAAAGTLTNFIKRNRTKLSDSVIKDFTRMILQGLVSI 125
Query: 1158 HSKGILHRDMKADNLLL----DNDG-----VCKISDFGISRKSNNIYS--NSDMTMRGTV 1206
H+ G +H D+K DN+LL D D KISDFGIS ++ + D GT
Sbjct: 126 HNHGYVHCDLKPDNILLFPLYDKDTWNCSYELKISDFGISTRAGDKSGCWRVDEPWVGTS 185
Query: 1207 FWMAPEMVDTAHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPD 1266
+M+PE V +D+WSLGC+VL+M+ GKRPW FE + ++ AP IP
Sbjct: 186 IYMSPESVSDGTTVEKTLDLWSLGCIVLKMYTGKRPWLGFEKDVKSLLL--NQKAPEIP- 242
Query: 1267 DTKDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPF 1302
+ + + FL++CF PE R +A L+ HPF
Sbjct: 243 ---ETLPCDARLFLEKCFSRKPEERGSASELLLHPF 275
>CE25046 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand protein
superfamily
Length = 348
Score = 122 bits (306), Expect = 4e-27
Identities = 91/293 (31%), Positives = 144/293 (49%), Gaps = 21/293 (7%)
Query: 1042 EIIGKGSFGAVYLALNVT-TGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNH 1100
+++G G+F V+LA + + G+M AVK + ++ES L++E+ L+ L H
Sbjct: 26 DVLGTGAFSKVFLAESKSDAGQMYAVKCIDKKALKGKEES-------LENEIKVLRKLRH 78
Query: 1101 VNIVQYLG-FEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHS 1159
NIVQ ++EK +Y L +E V GG + I G + +Q +L +QVLE + ++H
Sbjct: 79 NNIVQLFDTYDEKQFVY-LVMELVTGGELFDRIVAKGSYTEQDASNLIRQVLEAVGFMHD 137
Query: 1160 KGILHRDMKADNLLL---DNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVDT 1216
G++HRD+K +NLL D D ISDFG+S+ + S T GT ++APE++
Sbjct: 138 NGVVHRDLKPENLLYYNQDEDSKIMISDFGLSKTED---SGVMATACGTPGYVAPEVLQ- 193
Query: 1217 AHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAG 1276
Y VD+WS+G + + G P+ + QI K + P D +S +
Sbjct: 194 QKPYGKAVDVWSIGVIAYILLCGYPPFYDESDANLFAQIIKGEYEFDAP--YWDQISDSA 251
Query: 1277 QSFLDQCFEIDPEMRPTADSLVGHPFC--KTSSSFDFPKTKLAQFIKSNDKLN 1327
+ F+ DPE R T + HP+ T+ + D T KS K N
Sbjct: 252 KDFITHLMCCDPEARFTCQDALSHPWISGNTAYTHDIHGTVAVHLKKSLAKRN 304
>At4g24400 [T] KOG0583 Serine/threonine protein kinase
Length = 445
Score = 122 bits (305), Expect = 5e-27
Identities = 84/257 (32%), Positives = 131/257 (50%), Gaps = 20/257 (7%)
Query: 1041 GEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAI---SMVEALKSEVSTLKD 1097
G IG+G+F V A N TGE +A+K V D S I MV+ +K E+S +K
Sbjct: 12 GRTIGEGTFAKVKFAQNTETGESVAMKIV--------DRSTIIKRKMVDQIKREISIMKL 63
Query: 1098 LNHVNIVQ-YLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAY 1156
+ H +V+ Y + IY + LEY+ GG + I GR + R Q+++G+ Y
Sbjct: 64 VRHPCVVRLYEVLASRTKIY-IILEYITGGELFDKIVRNGRLSESEARKYFHQLIDGVDY 122
Query: 1157 LHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVDT 1216
HSKG+ HRD+K +NLLLD+ G KISDFG+S + T GT ++APE++
Sbjct: 123 CHSKGVYHRDLKPENLLLDSQGNLKISDFGLSALPEQGVTILKTTC-GTPNYVAPEVLSH 181
Query: 1217 AHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAG 1276
A DIWS G ++ + AG P+ ++ +I K++ + P +
Sbjct: 182 KGYNGAVADIWSCGVILYVLMAGYLPFDEMDLPTLYSKIDKAEFSCP------SYFALGA 235
Query: 1277 QSFLDQCFEIDPEMRPT 1293
+S +++ + +PE R T
Sbjct: 236 KSLINRILDPNPETRIT 252
>At3g06620 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 773
Score = 122 bits (305), Expect = 5e-27
Identities = 98/357 (27%), Positives = 169/357 (46%), Gaps = 30/357 (8%)
Query: 958 SRGESSQFLTP-VKSLKPPKRTKTIRIIAQEASEARKNEVSQKLQRKNTKMWGTKVVEIT 1016
S+G + + P V++ + +R I A E+ E ++ + + + +W + + +
Sbjct: 401 SKGRPTNSVWPWVQNEQKKERCHQINPSAGVQYESHAFESNKPINNEASSLWSSPINANS 460
Query: 1017 DKRTIS--------INK-SRNSRGEYKEFAWIK---GEIIGKGSFGAVYLALNVTTGEML 1064
S +NK +S G E W GE +G+GS G VY L G +
Sbjct: 461 TSSASSCGSTSSSVMNKVDTDSEGLEYEILWDDLTIGEQVGQGSCGTVYHGL--WFGSDV 518
Query: 1065 AVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHVNIVQYLGFEEKNGIYSLFLEYVA 1124
AVK + E+S++ ++E+ K EV +K L H N++ ++G + E++
Sbjct: 519 AVKVFSKQEYSAE------VIESFKQEVLLMKRLRHPNVLLFMGAVTSPQRLCIVSEFLP 572
Query: 1125 GGSVGSLI-RMYGRFDDQLIRHLTKQVLEGLAYLH--SKGILHRDMKADNLLLDNDGVCK 1181
GS+ L+ + + D + H+ + G+ YLH S I+HRD+K+ NLL+D + K
Sbjct: 573 RGSLFRLLQKSTSKLDWRRRIHMALDIARGMNYLHHCSPPIIHRDLKSSNLLVDKNWTVK 632
Query: 1182 ISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVDTAHGYSAKVDIWSLGCVVLEMFAGKR 1241
++DFG+SR + Y S + +GT WMAPE++ K DI+S G V+ E+ K
Sbjct: 633 VADFGLSRIKHETYLTS-KSGKGTPQWMAPEVLRN-ESADEKSDIYSFGVVLWELATEKI 690
Query: 1242 PWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQSFLDQCFEIDPEMRPTADSLV 1298
PW + + +G IP D + P S ++ C+ D ++RPT L+
Sbjct: 691 PWETLNSMQVIGAVGFMDQRLEIPKD----IDPRWISLMESCWHSDTKLRPTFQELM 743
>YPL140c [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K)
Length = 506
Score = 121 bits (304), Expect = 6e-27
Identities = 86/277 (31%), Positives = 145/277 (52%), Gaps = 32/277 (11%)
Query: 1043 IIGKGSFGAVYLALNVTTGEMLAVKQV----TVPEFSSQDESAISMVEALKSEVSTLKDL 1098
I+G+G+ G+V ++ A+K + T PE+ Q + ++ KS+
Sbjct: 219 ILGEGAGGSVAKCRLKNGKKVFALKTINTMNTDPEYQKQIFRELQFNKSFKSDY------ 272
Query: 1099 NHVNIVQYLGF---EEKNGIYSLFLEYVAGGSVGS----LIRMYGRFDDQLIRHLTKQVL 1151
IVQY G E+ + IY + +EY+ G S+ + L++ GR +++I + + VL
Sbjct: 273 ----IVQYYGMFTDEQSSSIY-IAMEYMGGKSLEATYKNLLKRGGRISERVIGKIAESVL 327
Query: 1152 EGLAYLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAP 1211
GL+YLH + ++HRD+K N+LL+ G K+ DFG+S ++ N + MT GT F+MAP
Sbjct: 328 RGLSYLHERKVIHRDIKPQNILLNEKGEIKLCDFGVSGEAVNSLA---MTFTGTSFYMAP 384
Query: 1212 EMVDTAHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEV---VAAMFQIGKSKTAPPIPDDT 1268
E + YS D+WSLG +LE+ G+ P+ + ++ VA + + T P D
Sbjct: 385 ERIQ-GQPYSVTCDVWSLGLTLLEVAGGRFPFESDKITQNVAPIELLTMILTFSPQLKDE 443
Query: 1269 KDL---VSPAGQSFLDQCFEIDPEMRPTADSLVGHPF 1302
+L S +SF+D C + D RP+ ++ HP+
Sbjct: 444 PELDISWSKTFRSFIDYCLKKDARERPSPRQMLKHPW 480
>Hs7657335 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1295
Score = 121 bits (304), Expect = 6e-27
Identities = 92/309 (29%), Positives = 151/309 (48%), Gaps = 33/309 (10%)
Query: 1042 EIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHV 1101
E++G G++G VY +V TG++ A+K + V E DE E +K E++ LK +H
Sbjct: 29 EVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTE----DEE-----EEIKQEINMLKKYSHH 79
Query: 1102 -NIVQYLG-FEEKNGIYS-----LFLEYVAGGSVGSLIRMY--GRFDDQLIRHLTKQVLE 1152
NI Y G F +K+ + L +E+ GSV L++ + I ++ +++L
Sbjct: 80 RNIATYYGAFIKKSPPGNDDQLWLVMEFCGAGSVTDLVKNTKGNALKEDCIAYICREILR 139
Query: 1153 GLAYLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPE 1212
GLA+LH+ ++HRD+K N+LL + K+ DFG+S + + + T GT +WMAPE
Sbjct: 140 GLAHLHAHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRN-TFIGTPYWMAPE 198
Query: 1213 MVDTAHG----YSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDT 1268
++ Y + DIWSLG +EM G P + + A+F I ++ P P
Sbjct: 199 VIACDENPDATYDYRSDIWSLGITAIEMAEGAPPLCDMHPMRALFLIPRN----PPPRLK 254
Query: 1269 KDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPFCKTSSSFDFPKTKLAQFIKSNDKLNS 1328
S F+D C RP + L+ PF + D P + + I+ D ++
Sbjct: 255 SKKWSKKFIDFIDTCLIKTYLSRPPTEQLLKFPFIR-----DQPTERQVR-IQLKDHIDR 308
Query: 1329 SRLRISSQE 1337
SR + +E
Sbjct: 309 SRKKRGEKE 317
>At5g58950 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 561
Score = 121 bits (304), Expect = 6e-27
Identities = 92/356 (25%), Positives = 164/356 (45%), Gaps = 31/356 (8%)
Query: 955 FLSSRGESSQFLTP-------VKSLKPP--------KRTKTIRIIAQEASEARKNEVSQK 999
F +R E +F TP K +KP KR+ +R + + + ++
Sbjct: 148 FKEARSERKRFSTPHPRRVESEKGMKPKLSHKNSFDKRSFNLRSPSGPIRDLGTLRIQER 207
Query: 1000 LQRKNTKMWGTKVVEITDKRTISINKSRNSRGEYKEFAWIKGEIIGKGSFGAVYLALNVT 1059
++ K W +K+ + T +R ++ S R + + + G G + +Y
Sbjct: 208 VKSKKDTGW-SKLFDNTGRRVSAVEASEEFRVDMSKLFF--GLKFAHGLYSRLYHGKY-- 262
Query: 1060 TGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHVNIVQYLGFEEKNGIYSLF 1119
+ +AVK +TVP+ + + EV+ L L H N+++++G + +Y +
Sbjct: 263 EDKAVAVKLITVPDDDDNGCLGARLEKQFTKEVTLLSRLTHPNVIKFVGAYKDPPVYCVL 322
Query: 1120 LEYVAGGSVGSLIRMYGRFDDQLIR--HLTKQVLEGLAYLHSKGILHRDMKADNLLLDND 1177
+Y+ GS+ S + L + + G+ Y+HS+ I+HRD+K +N+L+D +
Sbjct: 323 TQYLPEGSLRSFLHKPENRSLPLKKLIEFAIDIARGMEYIHSRRIIHRDLKPENVLIDEE 382
Query: 1178 GVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVD-TAHGYSAKVDIWSLGCVVLEM 1236
KI+DFGI+ + Y + GT WMAPEM+ HG K D++S G V+ EM
Sbjct: 383 FHLKIADFGIACEEE--YCDMLADDPGTYRWMAPEMIKRKPHG--RKADVYSFGLVLWEM 438
Query: 1237 FAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQSFLDQCFEIDPEMRP 1292
AG P+ + + A F + P IP D A ++ ++QC+ + P+ RP
Sbjct: 439 VAGAIPYEDMNPIQAAFAVVHKNIRPAIPGD----CPVAMKALIEQCWSVAPDKRP 490
>At1g62400 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 345
Score = 121 bits (304), Expect = 6e-27
Identities = 82/281 (29%), Positives = 139/281 (49%), Gaps = 26/281 (9%)
Query: 1029 SRGEYKEFA-----WIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAIS 1083
S+GE +E+ G G+ +Y + +AVK V +P + ++E+
Sbjct: 27 SKGEREEWTADLSQLFIGNKFASGAHSRIYRG--IYKQRAVAVKMVRIP--THKEETRAK 82
Query: 1084 MVEALKSEVSTLKDLNHVNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDD--- 1140
+ + KSEV+ L L H NIVQ++ +K +Y + EY++ G+ +RMY +
Sbjct: 83 LEQQFKSEVALLSRLFHPNIVQFIAACKKPPVYCIITEYMSQGN----LRMYLNKKEPYS 138
Query: 1141 ---QLIRHLTKQVLEGLAYLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSN 1197
+ + L + G+ YLHS+G++HRD+K++NLLL+++ K++DFG S
Sbjct: 139 LSIETVLRLALDISRGMEYLHSQGVIHRDLKSNNLLLNDEMRVKVADFGTSCLETQ--CR 196
Query: 1198 SDMTMRGTVFWMAPEMVDTAHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGK 1257
GT WMAPEM+ Y+ KVD++S G V+ E+ P+ V A F + +
Sbjct: 197 EAKGNMGTYRWMAPEMI-KEKPYTRKVDVYSFGIVLWELTTALLPFQGMTPVQAAFAVAE 255
Query: 1258 SKTAPPIPDDTKDLVSPAGQSFLDQCFEIDPEMRPTADSLV 1298
PP+P + PA + +C+ +P RP ++V
Sbjct: 256 KNERPPLPASCQ----PALAHLIKRCWSENPSKRPDFSNIV 292
>HsM4758524 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1165
Score = 121 bits (303), Expect = 8e-27
Identities = 82/276 (29%), Positives = 136/276 (48%), Gaps = 27/276 (9%)
Query: 1042 EIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHV 1101
E++G G++G VY +V TG++ A+K + V E DE E +K E++ LK +H
Sbjct: 29 EVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTE----DEE-----EEIKLEINMLKKYSHH 79
Query: 1102 -NIVQYLGFEEKNGIYS------LFLEYVAGGSVGSLIRMY--GRFDDQLIRHLTKQVLE 1152
NI Y G K L +E+ GS+ L++ + I ++++++L
Sbjct: 80 RNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIAYISREILR 139
Query: 1153 GLAYLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPE 1212
GLA+LH ++HRD+K N+LL + K+ DFG+S + + + T GT +WMAPE
Sbjct: 140 GLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRN-TFIGTPYWMAPE 198
Query: 1213 MVDTAHG----YSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDT 1268
++ Y + D+WS G +EM G P + + A+F I ++ P P
Sbjct: 199 VIACDENPDATYDYRSDLWSCGITAIEMAEGAPPLCDMHPMRALFLIPRN----PPPRLK 254
Query: 1269 KDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPFCK 1304
S SF++ C + RP+ + L+ HPF +
Sbjct: 255 SKKWSKKFFSFIEGCLVKNYMQRPSTEQLLKHPFIR 290
>Hs22035606 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1212
Score = 121 bits (303), Expect = 8e-27
Identities = 82/276 (29%), Positives = 136/276 (48%), Gaps = 27/276 (9%)
Query: 1042 EIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHV 1101
E++G G++G VY +V TG++ A+K + V E DE E +K E++ LK +H
Sbjct: 29 EVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTE----DEE-----EEIKLEINMLKKYSHH 79
Query: 1102 -NIVQYLGFEEKNGIYS------LFLEYVAGGSVGSLIRMY--GRFDDQLIRHLTKQVLE 1152
NI Y G K L +E+ GS+ L++ + I ++++++L
Sbjct: 80 RNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIAYISREILR 139
Query: 1153 GLAYLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPE 1212
GLA+LH ++HRD+K N+LL + K+ DFG+S + + + T GT +WMAPE
Sbjct: 140 GLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRN-TFIGTPYWMAPE 198
Query: 1213 MVDTAHG----YSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDT 1268
++ Y + D+WS G +EM G P + + A+F I ++ P P
Sbjct: 199 VIACDENPDATYDYRSDLWSCGITAIEMAEGAPPLCDMHPMRALFLIPRN----PPPRLK 254
Query: 1269 KDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPFCK 1304
S SF++ C + RP+ + L+ HPF +
Sbjct: 255 SKKWSKKFFSFIEGCLVKNYMQRPSTEQLLKHPFIR 290
>Hs22035604 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1320
Score = 121 bits (303), Expect = 8e-27
Identities = 82/276 (29%), Positives = 136/276 (48%), Gaps = 27/276 (9%)
Query: 1042 EIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHV 1101
E++G G++G VY +V TG++ A+K + V E DE E +K E++ LK +H
Sbjct: 29 EVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTE----DEE-----EEIKLEINMLKKYSHH 79
Query: 1102 -NIVQYLGFEEKNGIYS------LFLEYVAGGSVGSLIRMY--GRFDDQLIRHLTKQVLE 1152
NI Y G K L +E+ GS+ L++ + I ++++++L
Sbjct: 80 RNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIAYISREILR 139
Query: 1153 GLAYLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPE 1212
GLA+LH ++HRD+K N+LL + K+ DFG+S + + + T GT +WMAPE
Sbjct: 140 GLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRN-TFIGTPYWMAPE 198
Query: 1213 MVDTAHG----YSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDT 1268
++ Y + D+WS G +EM G P + + A+F I ++ P P
Sbjct: 199 VIACDENPDATYDYRSDLWSCGITAIEMAEGAPPLCDMHPMRALFLIPRN----PPPRLK 254
Query: 1269 KDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPFCK 1304
S SF++ C + RP+ + L+ HPF +
Sbjct: 255 SKKWSKKFFSFIEGCLVKNYMQRPSTEQLLKHPFIR 290
>Hs22035602 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1166
Score = 121 bits (303), Expect = 8e-27
Identities = 82/276 (29%), Positives = 136/276 (48%), Gaps = 27/276 (9%)
Query: 1042 EIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHV 1101
E++G G++G VY +V TG++ A+K + V E DE E +K E++ LK +H
Sbjct: 29 EVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTE----DEE-----EEIKLEINMLKKYSHH 79
Query: 1102 -NIVQYLGFEEKNGIYS------LFLEYVAGGSVGSLIRMY--GRFDDQLIRHLTKQVLE 1152
NI Y G K L +E+ GS+ L++ + I ++++++L
Sbjct: 80 RNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIAYISREILR 139
Query: 1153 GLAYLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPE 1212
GLA+LH ++HRD+K N+LL + K+ DFG+S + + + T GT +WMAPE
Sbjct: 140 GLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRN-TFIGTPYWMAPE 198
Query: 1213 MVDTAHG----YSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDT 1268
++ Y + D+WS G +EM G P + + A+F I ++ P P
Sbjct: 199 VIACDENPDATYDYRSDLWSCGITAIEMAEGAPPLCDMHPMRALFLIPRN----PPPRLK 254
Query: 1269 KDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPFCK 1304
S SF++ C + RP+ + L+ HPF +
Sbjct: 255 SKKWSKKFFSFIEGCLVKNYMQRPSTEQLLKHPFIR 290
>CE26649 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 648
Score = 121 bits (303), Expect = 8e-27
Identities = 84/276 (30%), Positives = 135/276 (48%), Gaps = 18/276 (6%)
Query: 1030 RGEYKEFAWIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALK 1089
RG Y E KG +GKG F Y N T E++A K V Q + + +
Sbjct: 34 RGTYYE----KGRFLGKGGFAHCYELTNRATREVVAGKVVPKSMLVKQYQR-----DKMT 84
Query: 1090 SEVSTLKDLNHVNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQ 1149
EV ++L H+NIV+ F E N + LE A S+ L + + R+ T Q
Sbjct: 85 QEVQIHRELGHINIVKLFNFFEDNLNVYITLELCARRSLMELHKRRKAVTEPEARYFTHQ 144
Query: 1150 VLEGLAYLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWM 1209
+++G+ YLH I+HRDMK NL L++D V KI DFG++ N T+ GT ++
Sbjct: 145 IVDGVLYLHDLNIIHRDMKLGNLFLNDDLVVKIGDFGLATTVNG--DERKKTLCGTPNYI 202
Query: 1210 APEMVDTAHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTK 1269
APE+++ A G+S +VDIW++GC++ + G+ P+ + + +I + P
Sbjct: 203 APEVLNKA-GHSFEVDIWAVGCILYILLFGQPPFESKSLEETYSRIRHNNYTIP------ 255
Query: 1270 DLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPFCKT 1305
+ + S + + + +P RPTA + F K+
Sbjct: 256 SIATQPAASLIRKMLDPEPTRRPTAKQVQRDGFFKS 291
>At5g45820 [T] KOG0583 Serine/threonine protein kinase
Length = 439
Score = 121 bits (303), Expect = 8e-27
Identities = 75/237 (31%), Positives = 128/237 (53%), Gaps = 11/237 (4%)
Query: 1041 GEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNH 1100
G ++G+G+F VY A N+ TGE +A+K + Q + + +++ +K E+S ++ + H
Sbjct: 15 GRLLGQGTFAKVYHARNIKTGESVAIKVI-----DKQKVAKVGLIDQIKREISVMRLVRH 69
Query: 1101 VNIV-QYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHS 1159
++V + K IY +EYV GG + + G+ + + R +Q++ + Y HS
Sbjct: 70 PHVVFLHEVMASKTKIY-FAMEYVKGGELFDKVSK-GKLKENIARKYFQQLIGAIDYCHS 127
Query: 1160 KGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDM-TMRGTVFWMAPEMVDTAH 1218
+G+ HRD+K +NLLLD +G KISDFG+S + + + T GT ++APE++
Sbjct: 128 RGVYHRDLKPENLLLDENGDLKISDFGLSALRESKQQDGLLHTTCGTPAYVAPEVIGKKG 187
Query: 1219 GYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPP--IPDDTKDLVS 1273
AK D+WS G V+ + AG P+ +V +I K + P P + K L+S
Sbjct: 188 YDGAKADVWSCGVVLYVLLAGFLPFHEQNLVEMYRKITKGEFKCPNWFPPEVKKLLS 244
>At1g18670 [D] KOG0600 Cdc2-related protein kinase
Length = 662
Score = 121 bits (303), Expect = 8e-27
Identities = 75/234 (32%), Positives = 121/234 (51%), Gaps = 9/234 (3%)
Query: 1033 YKEFAWIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEV 1092
++ A+ K E IG+G++ +V+ A TG ++A+K+V F + V + E+
Sbjct: 126 FRSDAFEKLEKIGQGTYSSVFRARETETGRIVALKKVRFDNFEPES------VRFMAREI 179
Query: 1093 STLKDLNHVNIVQYLGFEEKNGIYSLFL--EYVAGGSVGSLIRMYGRFDDQLIRHLTKQV 1150
L+ LNH NI++ G S+ L EY+ G L F I+ KQ+
Sbjct: 180 LILRKLNHPNIIKLEGIVTSKLSCSIHLVFEYMEHDLTGLLSSPDIDFTTPQIKCYMKQL 239
Query: 1151 LEGLAYLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFW-M 1209
L GL + H++G++HRD+K NLL++N+G+ K++DFG++ N + +T R W
Sbjct: 240 LSGLDHCHARGVMHRDIKGSNLLVNNEGILKVADFGLANFCNASGNKQPLTSRVVTLWYR 299
Query: 1210 APEMVDTAHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPP 1263
PE++ A Y A VD+WS+GCV E+ GK V + +I K +PP
Sbjct: 300 PPELLLGATEYGASVDLWSVGCVFAELLIGKPVLQGRTEVEQLHKIFKLCGSPP 353
>HsM5454184 [T] KOG4721 Serine/threonine protein kinase contains leucine zipper
domain
Length = 859
Score = 120 bits (302), Expect = 1e-26
Identities = 77/257 (29%), Positives = 131/257 (50%), Gaps = 24/257 (9%)
Query: 1044 IGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHVNI 1103
+G G+ GAV+L GE +AVK+V + ++++ L+ L H NI
Sbjct: 131 VGSGAQGAVFLGR--FHGEEVAVKKVR---------------DLKETDIKHLRKLKHPNI 173
Query: 1104 VQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHSKGIL 1163
+ + G + Y + +E+ A G + ++R L+ + + G+ YLH I+
Sbjct: 174 ITFKGVCTQAPCYCILMEFCAQGQLYEVLRAGRPVTPSLLVDWSMGIAGGMNYLHLHKII 233
Query: 1164 HRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVDTAHGYSAK 1223
HRD+K+ N+L+ D V KISDFG S++ ++ ++ M+ GTV WMAPE++ S K
Sbjct: 234 HRDLKSPNMLITYDDVVKISDFGTSKELSD--KSTKMSFAGTVAWMAPEVIRN-EPVSEK 290
Query: 1224 VDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQSFLDQC 1283
VDIWS G V+ E+ G+ P+ + + A ++ +G + P+P D + L QC
Sbjct: 291 VDIWSFGVVLWELLTGEIPYKDVDSSAIIWGVGSNSLHLPVPSSCPD----GFKILLRQC 346
Query: 1284 FEIDPEMRPTADSLVGH 1300
+ P RP+ ++ H
Sbjct: 347 WNSKPRNRPSFRQILLH 363
>Hs21735552 [T] KOG4721 Serine/threonine protein kinase contains leucine zipper
domain
Length = 859
Score = 120 bits (302), Expect = 1e-26
Identities = 77/257 (29%), Positives = 131/257 (50%), Gaps = 24/257 (9%)
Query: 1044 IGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHVNI 1103
+G G+ GAV+L GE +AVK+V + ++++ L+ L H NI
Sbjct: 131 VGSGAQGAVFLGR--FHGEEVAVKKVR---------------DLKETDIKHLRKLKHPNI 173
Query: 1104 VQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHSKGIL 1163
+ + G + Y + +E+ A G + ++R L+ + + G+ YLH I+
Sbjct: 174 ITFKGVCTQAPCYCILMEFCAQGQLYEVLRAGRPVTPSLLVDWSMGIAGGMNYLHLHKII 233
Query: 1164 HRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVDTAHGYSAK 1223
HRD+K+ N+L+ D V KISDFG S++ ++ ++ M+ GTV WMAPE++ S K
Sbjct: 234 HRDLKSPNMLITYDDVVKISDFGTSKELSD--KSTKMSFAGTVAWMAPEVIRN-EPVSEK 290
Query: 1224 VDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQSFLDQC 1283
VDIWS G V+ E+ G+ P+ + + A ++ +G + P+P D + L QC
Sbjct: 291 VDIWSFGVVLWELLTGEIPYKDVDSSAIIWGVGSNSLHLPVPSSCPD----GFKILLRQC 346
Query: 1284 FEIDPEMRPTADSLVGH 1300
+ P RP+ ++ H
Sbjct: 347 WNSKPRNRPSFRQILLH 363
>CE28273 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1096
Score = 120 bits (302), Expect = 1e-26
Identities = 83/299 (27%), Positives = 145/299 (47%), Gaps = 33/299 (11%)
Query: 1021 ISINKSRNSRGEYKEFAWIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDES 1080
I +N R+ G ++ E++G G++G VY +V T ++ A+K + + E +DE
Sbjct: 9 IDLNSLRDPAGIFELI-----EVVGNGTYGQVYKGRHVKTAQLAAIKIMNINE-DEEDE- 61
Query: 1081 AISMVEALKSEVSTLKD-LNHVNIVQYLGF--------EEKNGIYSLFLEYVAGGSVGSL 1131
+K E++ LK +H N+ Y G K+ L +E+ GS+ L
Sbjct: 62 -------IKLEINMLKKHSHHRNVATYYGAFIKKLPSSTGKHDQLWLVMEFCGSGSITDL 114
Query: 1132 IRMY--GRFDDQLIRHLTKQVLEGLAYLHSKGILHRDMKADNLLLDNDGVCKISDFGISR 1189
++ G ++ I ++ +++L GL +LH ++HRD+K N+LL + K+ DFG+S
Sbjct: 115 VKNTKGGSLKEEWIAYICREILRGLYHLHQSKVIHRDIKGQNVLLTDSAEVKLVDFGVSA 174
Query: 1190 KSNNIYSNSDMTMRGTVFWMAPEMVDTAHG----YSAKVDIWSLGCVVLEMFAGKRPWSN 1245
+ + + T GT +WMAPE++ Y ++ D+WSLG LEM G P +
Sbjct: 175 QLDKTVGRRN-TFIGTPYWMAPEVIACDESPEATYDSRSDLWSLGITALEMAEGHPPLCD 233
Query: 1246 FEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPFCK 1304
+ A+F I ++ PP + ++F++ D RP +L+ HPF K
Sbjct: 234 MHPMRALFLIPRN---PPPKLKRNKKWTKKFETFIETVLVKDYHQRPYTGALLRHPFIK 289
>CE25673 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1082
Score = 120 bits (302), Expect = 1e-26
Identities = 83/299 (27%), Positives = 145/299 (47%), Gaps = 33/299 (11%)
Query: 1021 ISINKSRNSRGEYKEFAWIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDES 1080
I +N R+ G ++ E++G G++G VY +V T ++ A+K + + E +DE
Sbjct: 9 IDLNSLRDPAGIFELI-----EVVGNGTYGQVYKGRHVKTAQLAAIKIMNINE-DEEDE- 61
Query: 1081 AISMVEALKSEVSTLKD-LNHVNIVQYLGF--------EEKNGIYSLFLEYVAGGSVGSL 1131
+K E++ LK +H N+ Y G K+ L +E+ GS+ L
Sbjct: 62 -------IKLEINMLKKHSHHRNVATYYGAFIKKLPSSTGKHDQLWLVMEFCGSGSITDL 114
Query: 1132 IRMY--GRFDDQLIRHLTKQVLEGLAYLHSKGILHRDMKADNLLLDNDGVCKISDFGISR 1189
++ G ++ I ++ +++L GL +LH ++HRD+K N+LL + K+ DFG+S
Sbjct: 115 VKNTKGGSLKEEWIAYICREILRGLYHLHQSKVIHRDIKGQNVLLTDSAEVKLVDFGVSA 174
Query: 1190 KSNNIYSNSDMTMRGTVFWMAPEMVDTAHG----YSAKVDIWSLGCVVLEMFAGKRPWSN 1245
+ + + T GT +WMAPE++ Y ++ D+WSLG LEM G P +
Sbjct: 175 QLDKTVGRRN-TFIGTPYWMAPEVIACDESPEATYDSRSDLWSLGITALEMAEGHPPLCD 233
Query: 1246 FEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPFCK 1304
+ A+F I ++ PP + ++F++ D RP +L+ HPF K
Sbjct: 234 MHPMRALFLIPRN---PPPKLKRNKKWTKKFETFIETVLVKDYHQRPYTGALLRHPFIK 289
>CE25672 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1087
Score = 120 bits (302), Expect = 1e-26
Identities = 83/299 (27%), Positives = 145/299 (47%), Gaps = 33/299 (11%)
Query: 1021 ISINKSRNSRGEYKEFAWIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDES 1080
I +N R+ G ++ E++G G++G VY +V T ++ A+K + + E +DE
Sbjct: 9 IDLNSLRDPAGIFELI-----EVVGNGTYGQVYKGRHVKTAQLAAIKIMNINE-DEEDE- 61
Query: 1081 AISMVEALKSEVSTLKD-LNHVNIVQYLGF--------EEKNGIYSLFLEYVAGGSVGSL 1131
+K E++ LK +H N+ Y G K+ L +E+ GS+ L
Sbjct: 62 -------IKLEINMLKKHSHHRNVATYYGAFIKKLPSSTGKHDQLWLVMEFCGSGSITDL 114
Query: 1132 IRMY--GRFDDQLIRHLTKQVLEGLAYLHSKGILHRDMKADNLLLDNDGVCKISDFGISR 1189
++ G ++ I ++ +++L GL +LH ++HRD+K N+LL + K+ DFG+S
Sbjct: 115 VKNTKGGSLKEEWIAYICREILRGLYHLHQSKVIHRDIKGQNVLLTDSAEVKLVDFGVSA 174
Query: 1190 KSNNIYSNSDMTMRGTVFWMAPEMVDTAHG----YSAKVDIWSLGCVVLEMFAGKRPWSN 1245
+ + + T GT +WMAPE++ Y ++ D+WSLG LEM G P +
Sbjct: 175 QLDKTVGRRN-TFIGTPYWMAPEVIACDESPEATYDSRSDLWSLGITALEMAEGHPPLCD 233
Query: 1246 FEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPFCK 1304
+ A+F I ++ PP + ++F++ D RP +L+ HPF K
Sbjct: 234 MHPMRALFLIPRN---PPPKLKRNKKWTKKFETFIETVLVKDYHQRPYTGALLRHPFIK 289
>CE23001 [R] KOG0589 Serine/threonine protein kinase
Length = 579
Score = 120 bits (302), Expect = 1e-26
Identities = 81/287 (28%), Positives = 140/287 (48%), Gaps = 17/287 (5%)
Query: 1011 KVVEITDKRTISINKSRNSRGEYKEFAWIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVT 1070
++VEI I I N R + + + +GKG+FG+ L ++ +K++
Sbjct: 145 RIVEIYINNEIMITNP-NPRATSAQNRYERIRTVGKGAFGSAVLYRRREDSSLVIIKEIN 203
Query: 1071 VPEF-SSQDESAISMVEALKSEVSTLKDLNHVNIVQYLGFEEKNGIYSLFLEYVAGGSVG 1129
+ + SSQ A++ EVS L + H NI+ Y E+ G+ + +EY GG++
Sbjct: 204 MYDLDSSQRRLALN-------EVSLLSRIEHPNIIAYYDSFEEEGVLMIEMEYADGGTLA 256
Query: 1130 SLI-RMYGRFDDQLIRHLTKQVLEGLAYLHSKGILHRDMKADNLLLDNDGVCKISDFGIS 1188
++ R D++ I + Q+ +AYLH +LHRD+K N+ L D KI DFGIS
Sbjct: 257 QMLSRTQNLLDEEQIGDMMIQMCSAVAYLHENSVLHRDLKTANVFLTRDSFVKIGDFGIS 316
Query: 1189 R-KSNNIYSNSDMTMRGTVFWMAPEMVDTAHGYSAKVDIWSLGCVVLEMFAGKRPWSNFE 1247
+ + T+ GT ++++PEM + Y+ K D+W+LGC++ EM K+ +
Sbjct: 317 KIMGTETLAQGAKTVVGTPYYISPEMC-SGVSYNEKSDMWALGCILYEMCCLKKAFEGDN 375
Query: 1248 VVAAMFQIGKSKTAPPIPDDTKDLVSPAGQSFLDQCFEIDPEMRPTA 1294
+ A + I P K S + + + ++DP+ RP+A
Sbjct: 376 LPALVNSIMTCAYTP-----VKGPYSAEMKMVIRELLQLDPQKRPSA 417
>At5g01810 [T] KOG0583 Serine/threonine protein kinase
Length = 421
Score = 120 bits (302), Expect = 1e-26
Identities = 76/261 (29%), Positives = 145/261 (55%), Gaps = 17/261 (6%)
Query: 1041 GEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNH 1100
G+ +G+G+F VY A ++ TG+ +A+K + + M E +K E+S ++ L H
Sbjct: 15 GKFLGQGTFAKVYHARHLKTGDSVAIKVIDKERILK-----VGMTEQIKREISAMRLLRH 69
Query: 1101 VNIVQ-YLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHS 1159
NIV+ + K+ IY + +E+V GG + + + G+ + + R +Q++ + + HS
Sbjct: 70 PNIVELHEVMATKSKIYFV-MEHVKGGELFNKVST-GKLREDVARKYFQQLVRAVDFCHS 127
Query: 1160 KGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDM-TMRGTVFWMAPEMVDTAH 1218
+G+ HRD+K +NLLLD G KISDFG+S S++ + + T GT ++APE++ + +
Sbjct: 128 RGVCHRDLKPENLLLDEHGNLKISDFGLSALSDSRRQDGLLHTTCGTPAYVAPEVI-SRN 186
Query: 1219 GYSA-KVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQ 1277
GY K D+WS G ++ + AG P+ + ++ +IGK++ P + ++P +
Sbjct: 187 GYDGFKADVWSCGVILFVLLAGYLPFRDSNLMELYKKIGKAEVKFP------NWLAPGAK 240
Query: 1278 SFLDQCFEIDPEMRPTADSLV 1298
L + + +P R + + ++
Sbjct: 241 RLLKRILDPNPNTRVSTEKIM 261
>At3g45790 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 376
Score = 120 bits (302), Expect = 1e-26
Identities = 91/279 (32%), Positives = 138/279 (48%), Gaps = 40/279 (14%)
Query: 1034 KEFAWIKGEIIGKGSFGAVYLALN--VTTGEMLAVKQVTVPEFSS-QDESAIS------- 1083
K +WIK E +G+GS+G+VYLA + T +A+K + SS DE I
Sbjct: 92 KSSSWIKSEFLGRGSYGSVYLATSKKAKTKTTMAIKSAEISRASSLMDEERILTRLSSPF 151
Query: 1084 MVEALKSEVSTLKDLNHVNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRM-YGRFDDQL 1142
+V E++ + L G E N Y+L LEY +G S+ L+ G ++
Sbjct: 152 IVRCYGHEIAREETL--------FGGERTN--YNLILEYCSGKSLFDLVNSNLGGLSEKD 201
Query: 1143 IRHLTKQVLEGLAYLHSKGILHRDMKADNLLL--------DNDGVCKISDFGIS-RKSNN 1193
++ L + +L GL Y+H I+H D+K +N+LL N V KI DFG++ K ++
Sbjct: 202 VKLLARDILYGLDYIHRANIIHCDIKPENILLAPVENRIRPNGYVAKIGDFGLALEKGSS 261
Query: 1194 IYSNSDMTMRGTVFWMAPEMVDTAHG-YSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAM 1252
Y + RGT +M+PE++ HG VD W+ GC VLEM G++ W + ++
Sbjct: 262 EYEKASGHRRGTTRYMSPELI--RHGIVDYAVDTWAFGCTVLEMLTGQQVWGEHSDLGSV 319
Query: 1253 ---FQIGKSKTAPPIPDDTKDLVSPAGQSFLDQCFEIDP 1288
IG+S P IP D +S Q FL +C + DP
Sbjct: 320 DWDILIGQSCYIPYIP----DWLSEEAQHFLSRCLKRDP 354
>At1g54610 [D] KOG0600 Cdc2-related protein kinase
Length = 572
Score = 120 bits (302), Expect = 1e-26
Identities = 109/453 (24%), Positives = 198/453 (43%), Gaps = 72/453 (15%)
Query: 940 GFEKSLKTKSEQQPAFLSSRGESSQFLTPVKSLKPPKRTKTIRIIAQEASEARKNEVSQK 999
G E + T +E + A SS+ S + S+ TK+ +IA + + + E +
Sbjct: 6 GREAATTTTAEAKQA-KSSKASSGVVVVGESSV-----TKSNGVIADDVEKKKNEEANGD 59
Query: 1000 LQRKNTKMWGTKVVEITDKRTISINKSRNSRGEYKEFAWI-------------------- 1039
+RK++K G + +S N S++ RGE W
Sbjct: 60 KERKSSK--GDRRRSTKPNPRLS-NPSKHWRGEQVAAGWPSWLSDACGEALNGWVPRKAD 116
Query: 1040 ---KGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLK 1096
K + IG+G++ VY A ++ TG+++A+K+V + V+ + E+ L+
Sbjct: 117 TFEKIDKIGQGTYSNVYKAKDMLTGKIVALKKVRFDNLEPES------VKFMAREILVLR 170
Query: 1097 DLNHVNIVQYLGFEEKNGIYSLFL--EYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGL 1154
L+H N+V+ G SL+L +Y+ G +F + ++ L +Q++ GL
Sbjct: 171 RLDHPNVVKLEGLVTSRMSCSLYLVFQYMDHDLAGLASSPVVKFSESEVKCLMRQLISGL 230
Query: 1155 AYLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMV 1214
+ HS+G+LHRD+K NLL+D+ GV KI+DFG++ + + + T+++ APE++
Sbjct: 231 EHCHSRGVLHRDIKGSNLLIDDGGVLKIADFGLATIFDPNHKRPMTSRVVTLWYRAPELL 290
Query: 1215 DTAHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAP------------ 1262
A Y +D+WS GC++ E+ AG+ V + +I K +P
Sbjct: 291 LGATDYGVGIDLWSAGCILAELLAGRPIMPGRTEVEQLHKIYKLCGSPSEDYWKKGKFTH 350
Query: 1263 ------------PIPDDTKDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPF-------C 1303
I + KD P+ +D I+PE R TA + + F C
Sbjct: 351 GAIYKPREPYKRSIRETFKDF-PPSSLPLIDALLSIEPEDRQTASAALKSEFFTSEPYAC 409
Query: 1304 KTSSSFDFPKTKLAQFIKSNDKLNSSRLRISSQ 1336
+ + +P +K + +++ R +Q
Sbjct: 410 EPADLPKYPPSKEIDAKRRDEETRRQRAASKAQ 442
>YKL101w [D] KOG0588 Serine/threonine protein kinase
Length = 1518
Score = 120 bits (300), Expect = 2e-26
Identities = 92/336 (27%), Positives = 156/336 (46%), Gaps = 50/336 (14%)
Query: 1022 SINKSRNSRGEYKEFAWIKGEIIGKGSFGAVYLALNVTTGEMLAVK-------------- 1067
S KSR++ G W G+ +GKGS G V LA N+ TG++ A+K
Sbjct: 70 SKRKSRDTVGP-----WKLGKTLGKGSSGRVRLAKNMETGQLAAIKIVPKKKAFVHCSNN 124
Query: 1068 --------------QVTVPEFSSQDESAISMVE--ALKSEVSTLKDLNHVNIVQYLGFEE 1111
V+ P +S++ S S ++ E+ +K ++H N++ E
Sbjct: 125 GTVPNSYSSSMVTSNVSSPSIASREHSNHSQTNPYGIEREIVIMKLISHTNVMALFEVWE 184
Query: 1112 KNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHSKGILHRDMKADN 1171
L LEYV GG + + G+ ++ H KQ++EG++Y HS I HRD+K +N
Sbjct: 185 NKSELYLVLEYVDGGELFDYLVSKGKLPEREAIHYFKQIVEGVSYCHSFNICHRDLKPEN 244
Query: 1172 LLLD-NDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVDTAHGYSAKVDIWSLG 1230
LLLD + KI+DFG++ + + + T G+ + +PE+V + D+WS G
Sbjct: 245 LLLDKKNRRIKIADFGMA--ALELPNKLLKTSCGSPHYASPEIVMGRPYHGGPSDVWSCG 302
Query: 1231 CVVLEMFAGKRPWS--NFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQSFLDQCFEIDP 1288
V+ + G P++ N + + Q GK + + + +DL+S + IDP
Sbjct: 303 IVLFALLTGHLPFNDDNIKKLLLKVQSGKYQMPSNLSSEARDLIS--------KILVIDP 354
Query: 1289 EMRPTADSLVGHPFCKTSSSFDFPKTKLAQFIKSND 1324
E R T ++ HP K D P K+ + ++ ++
Sbjct: 355 EKRITTQEILKHPLIKKYD--DLPVNKVLRKMRKDN 388
>SPBC32C12.03c [T] KOG0583 Serine/threonine protein kinase
Length = 423
Score = 120 bits (300), Expect = 2e-26
Identities = 87/303 (28%), Positives = 136/303 (44%), Gaps = 30/303 (9%)
Query: 1019 RTISINKSRNSRGEYKEFA-----------WIKGEIIGKGSFGAVYLALNVTTGEMLAVK 1067
+ I IN+S + +F WI + IG GS G V L +N+ TGE A+K
Sbjct: 23 QNIKINQSTKHQRSISDFVGTAGPGRQVGNWIIKKTIGAGSMGKVKLVVNILTGEKAALK 82
Query: 1068 QVTVPEFSSQDESAISMVEALKSEVSTLKDLNHVNIVQYLGFEEKNGIYSLFLEYVAGGS 1127
+ ++ + EAL + L H NI + + + EYV GG
Sbjct: 83 MIPFTPNNTSQTVRVQR-EALLGRL-----LRHPNICRVIDCIRTPACTYILFEYVPGGQ 136
Query: 1128 VGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHSKGILHRDMKADNLLLDNDG-VCKISDFG 1186
+ I G+ D+ L R Q++ L YLH I+HRD+K +N+LL D K+ DFG
Sbjct: 137 LLEYILARGKLDEDLARSFAMQLINALVYLHKNFIVHRDLKIENVLLTQDSRQVKLIDFG 196
Query: 1187 ISRKSNNIYSNSDM--TMRGTVFWMAPEMVDTAHGYSAKVDIWSLGCVVLEMFAGKRPWS 1244
+S N YS D+ T G++++ APE++D +VD+WSLG V+ M G+ P+
Sbjct: 197 LS----NFYSKDDLLRTYCGSLYFAAPELLDAKPYIGPEVDVWSLGVVIYVMVCGRVPFD 252
Query: 1245 NFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPFCK 1304
+ V +I K P +S S + ++P R + + P+ K
Sbjct: 253 DVSVPMLHSKIKSGKLEFP------SYISEDCCSLIAAMLNVNPRKRCSLEQAAKFPWLK 306
Query: 1305 TSS 1307
+S
Sbjct: 307 KNS 309
>HsM7657627 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 970
Score = 120 bits (300), Expect = 2e-26
Identities = 90/301 (29%), Positives = 149/301 (48%), Gaps = 29/301 (9%)
Query: 1041 GEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAI---SMVEALKSEVSTLKD 1097
G ++GKGSF VY A ++ TG +A+K + D+ A+ MV+ +K+EV
Sbjct: 15 GNLLGKGSFAGVYRAESIHTGLEVAIKMI--------DKKAMYKAGMVQRVKNEVKIHCQ 66
Query: 1098 LNHVNIVQ-YLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGR-FDDQLIRHLTKQVLEGLA 1155
L H +I++ Y FE+ N +Y L LE G + ++ + F + RH Q++ G+
Sbjct: 67 LKHPSILELYNYFEDSNYVY-LVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQIITGML 125
Query: 1156 YLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVD 1215
YLHS GILHRD+ NLLL + KI+DFG++ + + T+ GT +++PE+
Sbjct: 126 YLHSHGILHRDLTLSNLLLTRNMNIKIADFGLATQL-KMPHEKHYTLCGTPNYISPEIAT 184
Query: 1216 -TAHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSP 1274
+AHG + D+WSLGC+ + G+ P+ V + ++ + P +S
Sbjct: 185 RSAHGLES--DVWSLGCMFYTLLIGRPPFDTDTVKNTLNKVVLADYEMP------TFLSI 236
Query: 1275 AGQSFLDQCFEIDPEMRPTADSLVGHPFCKTSSSFDFPKTKLAQFIKSNDKLNSSRLRIS 1334
+ + Q +P R + S++ HPF +SS TK D ++S IS
Sbjct: 237 EAKDLIHQLLRRNPADRLSLSSVLDHPFMSRNSS-----TKSKDLGTVEDSIDSGHATIS 291
Query: 1335 S 1335
+
Sbjct: 292 T 292
>At5g10930 [T] KOG0583 Serine/threonine protein kinase
Length = 445
Score = 120 bits (300), Expect = 2e-26
Identities = 80/290 (27%), Positives = 143/290 (48%), Gaps = 16/290 (5%)
Query: 1041 GEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNH 1100
G ++GKG+F VY + GE +A+K + + + M+E +K E+S +K + H
Sbjct: 15 GRLLGKGTFAKVYYGKEIIGGECVAIKVINKDQVMKRP----GMMEQIKREISIMKLVRH 70
Query: 1101 VNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHSK 1160
NIV+ +E+V GG + I G+ + R +Q++ + Y HS+
Sbjct: 71 PNIVELKEVMATKTKIFFVMEFVKGGELFCKISK-GKLHEDAARRYFQQLISAVDYCHSR 129
Query: 1161 GILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDM-TMRGTVFWMAPEMVDTAHG 1219
G+ HRD+K +NLLLD +G KISDFG+S I + + T GT ++APE++
Sbjct: 130 GVSHRDLKPENLLLDENGDLKISDFGLSALPEQILQDGLLHTQCGTPAYVAPEVLKKKGY 189
Query: 1220 YSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQSF 1279
AK DIWS G V+ + AG P+ + ++ +I ++ P SP +
Sbjct: 190 DGAKADIWSCGVVLYVLLAGCLPFQDENLMNMYRKIFRADFEFP------PWFSPEARRL 243
Query: 1280 LDQCFEIDPEMRPTADSLVGHPFCKTS----SSFDFPKTKLAQFIKSNDK 1325
+ + +DP+ R + +++ P+ + + +F + +Q K+N++
Sbjct: 244 ISKLLVVDPDRRISIPAIMRTPWLRKNFTPPLAFKIDEPICSQSSKNNEE 293
>At1g33770 [D] KOG0600 Cdc2-related protein kinase
Length = 614
Score = 120 bits (300), Expect = 2e-26
Identities = 90/308 (29%), Positives = 151/308 (48%), Gaps = 46/308 (14%)
Query: 1044 IGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHVNI 1103
IG+G++ VY A ++ TG+++A+K+V F++ D ++ + E++ L+ L+H N+
Sbjct: 147 IGQGTYSIVYKARDLETGKIVAMKKV---RFANMDPESVRF---MAREINILRKLDHPNV 200
Query: 1104 V--QYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHSKG 1161
+ Q L + +G L EY+ G +R +F + I+ KQ+L GL + HS+G
Sbjct: 201 MKLQCLVTSKLSGSLHLVFEYMEHDLSGLALRPGVKFTEPQIKCFMKQLLCGLEHCHSRG 260
Query: 1162 ILHRDMKADNLLLDNDGVCKISDFGISRKSNNIY---SNSDMTMRGTVFW-MAPEMVDTA 1217
ILHRD+K NLL++NDGV KI DFG++ + Y + +T R W APE++ +
Sbjct: 261 ILHRDIKGSNLLVNNDGVLKIGDFGLA----SFYKPDQDQPLTSRVVTLWYRAPELLLGS 316
Query: 1218 HGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPP-------------- 1263
Y +D+WS+GC++ E+F K V M +I K +P
Sbjct: 317 TEYGPAIDLWSVGCILAELFVCKPIMPGRTEVEQMHKIFKLCGSPSEEFWNTTKFPQATS 376
Query: 1264 ---------IPDDTKDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPF-------CKTSS 1307
+ +T +S + LD+ ++PE R +A S + F C SS
Sbjct: 377 YKPQHPYKRVLLETFKNLSSSSLDLLDKLLSVEPEKRCSASSTLLSEFFTTEPLPCHISS 436
Query: 1308 SFDFPKTK 1315
+P +K
Sbjct: 437 LPKYPPSK 444
>Hs7706549 [D] KOG0600 Cdc2-related protein kinase
Length = 1490
Score = 119 bits (299), Expect = 2e-26
Identities = 83/297 (27%), Positives = 137/297 (45%), Gaps = 42/297 (14%)
Query: 1043 IIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHVN 1102
IIG+G++G VY A + TGE++A+K+V + +E + A++ E+ L+ L H +
Sbjct: 732 IIGEGTYGQVYKARDKDTGELVALKKVRL-----DNEKEGFPITAIR-EIKILRQLIHRS 785
Query: 1103 IVQY----------LGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLE 1152
+V L F++ G + L EY+ +G L F + I+ KQ++E
Sbjct: 786 VVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFMKQLME 845
Query: 1153 GLAYLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPE 1212
GL Y H K LHRD+K N+LL+N G K++DFG++R N+ S T+++ PE
Sbjct: 846 GLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLWYRPPE 905
Query: 1213 MVDTAHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLV 1272
++ Y+ +D+WS GC++ E+F K+P + A ++ P P D++
Sbjct: 906 LLLGEERYTPAIDVWSCGCILGELFT-KKPIFQANLELAQLELISRLCGSPCPAVWPDVI 964
Query: 1273 S-------------------------PAGQSFLDQCFEIDPEMRPTADSLVGHPFCK 1304
A LD +DP R TA+ + F K
Sbjct: 965 KLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFLK 1021
>CE24761 [D] KOG0580 Serine/threonine protein kinase
Length = 305
Score = 119 bits (299), Expect = 2e-26
Identities = 87/290 (30%), Positives = 143/290 (49%), Gaps = 20/290 (6%)
Query: 1012 VVEITDKRTISINKSRNSRGEYKEFAWIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTV 1071
V+ + +K T++ + G++ + G +GKG FG+VYLA T +A+K +
Sbjct: 7 VINLPEKETVN---TPQKGGKFTINDFEIGRPLGKGKFGSVYLARTKTGHFHVAIKVL-- 61
Query: 1072 PEFSSQDESAISMVEALKSEVSTLKDLNHVNIVQ-YLGFEEKNGIYSLFLEYVAGGSVGS 1130
F SQ S + L+ E+ LNH NI++ Y F + IY L LEY GG +
Sbjct: 62 --FKSQLISG-GVEHQLEREIEIQSHLNHPNIIKLYTYFWDAKKIY-LVLEYAPGGEMYK 117
Query: 1131 LIRMYGRFDDQLIRHLTKQVLEGLAYLHSKGILHRDMKADNLLLDNDGVCKISDFGISRK 1190
+ + RF + ++ + L+Y H K ++HRD+K +NLL+ + G KI DFG S
Sbjct: 118 QLTVSKRFSEPTAAKYMYEIADALSYCHRKNVIHRDIKPENLLIGSQGELKIGDFGWSVH 177
Query: 1191 SNNIYSNSDMTMRGTVFWMAPEMVDTAHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVA 1250
+ SN TM GT+ ++ PEMV+ A +S VD+W++G + E GK P+ + +
Sbjct: 178 AP---SNKRQTMCGTMDYLPPEMVNGA-DHSDAVDLWAIGVLCYEFLVGKPPFEHEDQSK 233
Query: 1251 AMFQIGKSKTAPPIPDDTKDLVSPAGQSFLDQCFEIDPEMRPTADSLVGH 1300
I ++ P D V + + + +DP+ R T + + H
Sbjct: 234 TYAAIKAARFTYP------DSVKKGARDLIGRLLVVDPKARCTLEQVKEH 277
>At4g14580 [T] KOG0583 Serine/threonine protein kinase
Length = 426
Score = 119 bits (298), Expect = 3e-26
Identities = 85/295 (28%), Positives = 150/295 (50%), Gaps = 18/295 (6%)
Query: 1041 GEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDL-N 1099
G +G GSF V++A +++TGE++A+K + Q M + E+ ++ L N
Sbjct: 24 GRRLGSGSFAKVHVARSISTGELVAIKII-----DKQKTIDSGMEPRIIREIEAMRRLHN 78
Query: 1100 HVNIVQ-YLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLH 1158
H N+++ + K+ IY L +EY AGG + + + +GR ++ R +Q+ L++ H
Sbjct: 79 HPNVLKIHEVMATKSKIY-LVVEYAAGGELFTKLIRFGRLNESAARRYFQQLASALSFCH 137
Query: 1159 SKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDM-TMRGTVFWMAPEMVDTA 1217
GI HRD+K NLLLD G K+SDFG+S + +N + T GT + APE++
Sbjct: 138 RDGIAHRDVKPQNLLLDKQGNLKVSDFGLSALPEHRSNNGLLHTACGTPAYTAPEVIAQR 197
Query: 1218 HGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQ 1277
AK D WS G + + AG P+ + +VA +I K P +S +
Sbjct: 198 GYDGAKADAWSCGVFLFVLLAGYVPFDDANIVAMYRKIHKRDYRFP------SWISKPAR 251
Query: 1278 SFLDQCFEIDPEMRPTADSLVGHPFCKTS---SSFDFPKTKLAQFIKSNDKLNSS 1329
S + + + +PE R + ++++G + + S S F +L +F++ K +++
Sbjct: 252 SIIYKLLDPNPETRMSIEAVMGTVWFQKSLEISEFQSSVFELDRFLEKEAKSSNA 306
>At2g37840 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 257
Score = 119 bits (298), Expect = 3e-26
Identities = 72/237 (30%), Positives = 123/237 (51%), Gaps = 13/237 (5%)
Query: 1038 WIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKD 1097
++ G IG GSF V+ A + G +A+K++ + + + + E+L SE+ L+
Sbjct: 12 YLVGRQIGSGSFSVVWEARHRVDGTEVAIKEIAMDRLNKK------LQESLMSEIFILRR 65
Query: 1098 LNHVNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYL 1157
+NH NI++ + + G L LEY GG + ++ +G + +H +Q+ GL L
Sbjct: 66 INHPNIIRLIDMIKSPGKVHLVLEYCKGGDLSVYVQRHGIVPEATAKHFMQQLAAGLQVL 125
Query: 1158 HSKGILHRDMKADNLLL---DNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMV 1214
I+HRD+K NLLL +ND KI+DFG +R T+ G+ +MAPE++
Sbjct: 126 RDNNIIHRDLKPQNLLLSTNENDADLKIADFGFARSLQP--RGLAETLCGSPLYMAPEIM 183
Query: 1215 DTAHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDL 1271
Y AK D+WS+G ++ ++ G+ P++ + + I +S T P D +DL
Sbjct: 184 Q-LQKYDAKADLWSVGAILFQLVTGRTPFTGNSQIQLLQNIIRS-TELHFPGDCRDL 238
>7301213 [R] KOG0589 Serine/threonine protein kinase
Length = 841
Score = 119 bits (298), Expect = 3e-26
Identities = 78/262 (29%), Positives = 129/262 (48%), Gaps = 17/262 (6%)
Query: 1040 KGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLN 1099
K ++G+GSFG L + G + KQ+ + E S + +EV L+
Sbjct: 107 KVRVVGQGSFGIAILYRRKSDGHQIVFKQINLSELSPPGR------DLAMNEVDVFSKLH 160
Query: 1100 HVNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLI-RMYGR--FDDQLIRHLTKQVLEGLAY 1156
H NIV YLG K+ + +EY GG++ +I G+ F ++ I + +Q+ + Y
Sbjct: 161 HPNIVSYLGSFIKDNTLLIEMEYADGGTLAQIIAERQGKLHFPERYIIAVFEQISSAINY 220
Query: 1157 LHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVDT 1216
+HS+ ILHRD+K N+ L+ G+ KI DFGIS+ N T+ GT ++ +PEM +
Sbjct: 221 MHSENILHRDLKTANVFLNRRGIVKIGDFGISKIMNT--KIHAQTVLGTPYYFSPEMCE- 277
Query: 1217 AHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAG 1276
Y K DIW+LGC++ EM K+ ++ + + +I P T L
Sbjct: 278 GKEYDNKSDIWALGCILGEMCCLKKTFAASNLSELVTKIMAGNYTPVPSGYTSGL----- 332
Query: 1277 QSFLDQCFEIDPEMRPTADSLV 1298
+S + +++ RPTA ++
Sbjct: 333 RSLMSNLLQVEAPRRPTASEVL 354
>CE26422 [D] KOG0600 Cdc2-related protein kinase
Length = 684
Score = 119 bits (297), Expect = 4e-26
Identities = 95/346 (27%), Positives = 164/346 (46%), Gaps = 53/346 (15%)
Query: 1015 ITDKRTISINKSRNSRGEYKEFA--WIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVP 1072
IT +R + N+ +S YK + + IG+G++G VY A+N TGE +A+K+V +
Sbjct: 286 ITTRRGHATNRPSDSDSWYKTNLTHYTMLDQIGEGTYGQVYKAVNNLTGEQVALKRVRL- 344
Query: 1073 EFSSQDESAISMVEALKSEVSTLKDLNHVNIVQYLGF----------EEKNGIYSLFLEY 1122
++E + A++ E+ L+ L+H NIV+ + + + L EY
Sbjct: 345 ----ENEKEGFPITAIR-EIKILRQLHHKNIVRLMDIVIDDISMDELKRTRANFYLVFEY 399
Query: 1123 VAGGSVGSL-IRMYGRFDDQLIRHLTKQVLEGLAYLHSKGILHRDMKADNLLLDNDGVCK 1181
V +G L + F+ I L KQ+LEGLAY+H+ G LHRD+K N+L++N G K
Sbjct: 400 VDHDLIGLLESKELVDFNKDQICSLFKQLLEGLAYIHNTGFLHRDIKCSNILVNNKGELK 459
Query: 1182 ISDFGISR---KSNNIYSNSDMTMRGTVFWMAPEMVDTAHGYSAKVDIWSLGCVVLEMFA 1238
I+D G++R K + +Y+N +T+ ++ PE++ Y +D+WS GC++ E+F
Sbjct: 460 IADLGLARLWEKESRLYTNRVITL----WYRPPELLLGDERYGPAIDVWSTGCMLGELFT 515
Query: 1239 GKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQS-------------------- 1278
K ++ + I K +P + D+ +L G +
Sbjct: 516 RKPLFNGNNEFGQLELISKVCGSPNV-DNWPELTELVGWNTFRMKRTYQRRIREEFEHIM 574
Query: 1279 ------FLDQCFEIDPEMRPTADSLVGHPFCKTSSSFDFPKTKLAQ 1318
LD+ ++PE R +A + HP+ ++ KL Q
Sbjct: 575 PREAVDLLDKMLTLNPEKRISAKEALNHPWIRSLEHTTVQPLKLPQ 620
>At1g30270 [T] KOG0583 Serine/threonine protein kinase
Length = 480
Score = 119 bits (297), Expect = 4e-26
Identities = 72/225 (32%), Positives = 119/225 (52%), Gaps = 9/225 (4%)
Query: 1041 GEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNH 1100
G +G+G+F V A NV G+ +A+K + + M+ +K E+ST+K + H
Sbjct: 34 GRTLGEGTFAKVKFARNVENGDNVAIKVIDKEKVLKN-----KMIAQIKREISTMKLIKH 88
Query: 1101 VNIVQYLG-FEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHS 1159
N+++ K IY + LE+V GG + I GR + R +Q++ + Y HS
Sbjct: 89 PNVIRMFEVMASKTKIYFV-LEFVTGGELFDKISSNGRLKEDEARKYFQQLINAVDYCHS 147
Query: 1160 KGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVDTAHG 1219
+G+ HRD+K +NLLLD +G K+SDFG+S T GT ++APE+++
Sbjct: 148 RGVYHRDLKPENLLLDANGALKVSDFGLSALPQQ-EDGLLHTTCGTPNYVAPEVINNKGY 206
Query: 1220 YSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSK-TAPP 1263
AK D+WS G ++ + AG P+ + + + +I K++ T PP
Sbjct: 207 DGAKADLWSCGVILFVLMAGYLPFEDSNLTSLYKKIFKAEFTCPP 251
>At1g29230 [T] KOG0583 Serine/threonine protein kinase
Length = 520
Score = 119 bits (297), Expect = 4e-26
Identities = 69/225 (30%), Positives = 121/225 (53%), Gaps = 9/225 (4%)
Query: 1041 GEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNH 1100
G+++G G+F VYLA N+ +G+ +A+K + + +V +K E+S L+ + H
Sbjct: 77 GKLLGHGTFAKVYLAQNIKSGDKVAIKVIDKEKIMKS-----GLVAHIKREISILRRVRH 131
Query: 1101 VNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHSK 1160
IV +EYV GG + + + GR ++ R +Q++ +++ H +
Sbjct: 132 PYIVHLFEVMATKSKIYFVMEYVGGGELFNTVAK-GRLPEETARRYFQQLISSVSFCHGR 190
Query: 1161 GILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNS-DMTMRGTVFWMAPEMVDTAHG 1219
G+ HRD+K +NLLLDN G K+SDFG+S + + + T GT ++APE++ T G
Sbjct: 191 GVYHRDLKPENLLLDNKGNLKVSDFGLSAVAEQLRQDGLCHTFCGTPAYIAPEVL-TRKG 249
Query: 1220 Y-SAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPP 1263
Y +AK D+WS G ++ + AG P+ + ++ +I K + P
Sbjct: 250 YDAAKADVWSCGVILFVLMAGHIPFYDKNIMVMYKKIYKGEFRCP 294
>YPL203w [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 380
Score = 118 bits (296), Expect = 6e-26
Identities = 80/252 (31%), Positives = 132/252 (51%), Gaps = 14/252 (5%)
Query: 1025 KSRNSRGEYKEFAWIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISM 1084
KS S+G+Y + +G GSFG V+L +V G A+K + Q +
Sbjct: 57 KSLVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVL-----KKQQVVKMKQ 111
Query: 1085 VEALKSEVSTLKDLNHVNIVQYLG-FEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLI 1143
VE E LK + H +++ G F++ I+ + ++Y+ GG + SL+R RF + +
Sbjct: 112 VEHTNDERRMLKLVEHPFLIRMWGTFQDARNIF-MVMDYIEGGELFSLLRKSQRFPNPVA 170
Query: 1144 RHLTKQVLEGLAYLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMR 1203
+ +V+ L YLH+ I++RD+K +N+LLD +G KI+DFG +++ + T+
Sbjct: 171 KFYAAEVILALEYLHAHNIIYRDLKPENILLDRNGHIKITDFGFAKEVQTV----TWTLC 226
Query: 1204 GTVFWMAPEMVDTAHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQI--GKSKTA 1261
GT ++APE++ T Y+ VD WSLG ++ EM AG P+ + + +I GK
Sbjct: 227 GTPDYIAPEVI-TTKPYNKSVDWWSLGVLIYEMLAGYTPFYDTTPMKTYEKILQGKVVYP 285
Query: 1262 PPIPDDTKDLVS 1273
P D DL+S
Sbjct: 286 PYFHPDVVDLLS 297
>At5g39420 [D] KOG0600 Cdc2-related protein kinase
Length = 576
Score = 118 bits (296), Expect = 6e-26
Identities = 72/209 (34%), Positives = 115/209 (54%), Gaps = 8/209 (3%)
Query: 1034 KEFAWIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVS 1093
K A+ K E IG+G++ +V+ A V TG+M+A+K+V Q ES + + E+
Sbjct: 101 KAEAFQKLEKIGQGTYSSVFRAREVETGKMVALKKVKFDNL--QPES----IRFMAREIL 154
Query: 1094 TLKDLNHVNIVQYLGFEEKNGIYSLFL--EYVAGGSVGSLIRMYGRFDDQLIRHLTKQVL 1151
L+ LNH NI++ G S++L EY+ G RF + I+ KQ+L
Sbjct: 155 ILRKLNHPNIMKLEGIVTSRASSSIYLVFEYMEHDLAGLSSNPDIRFTEPQIKCYMKQLL 214
Query: 1152 EGLAYLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAP 1211
GL + H +G++HRD+KA N+L++N GV K+ DFG++ N + T+++ AP
Sbjct: 215 WGLEHCHMRGVIHRDIKASNILVNNKGVLKLGDFGLANVVTPSNKNQLTSRVVTLWYRAP 274
Query: 1212 EMVDTAHGYSAKVDIWSLGCVVLEMFAGK 1240
E++ + Y VD+WS+GCV E+ GK
Sbjct: 275 ELLMGSTSYGVSVDLWSVGCVFAEILMGK 303
>At2g42550 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 344
Score = 118 bits (296), Expect = 6e-26
Identities = 96/294 (32%), Positives = 144/294 (48%), Gaps = 32/294 (10%)
Query: 1042 EIIGKGSFGAVYLALNVTTGE-----MLAVKQVTVPEFSSQDESA--ISMVEALKSEVST 1094
+ + KG++G+V L + + AVK +++S + +S +E + V
Sbjct: 9 KFLRKGAYGSVDLVKYIKRDDNALPLYAAVKTAECEDYNSLEREIQILSKLEGCRRIVQC 68
Query: 1095 LKDLNHVNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYG--RFDDQLIRHLTKQVLE 1152
+ GF +Y + +EY A GS+ S + Y + + +I+ T+ +L+
Sbjct: 69 YGNYTLEEDFDVGGFR----VYKMVMEYAAAGSLFSFMDSYKDRKLPETMIKDFTRMILQ 124
Query: 1153 GLAYLHSKGILHRDMKADNLLL---DNDGVCKISDFGISRKSNNIYSNS---DMTMRGTV 1206
GL +H G +H D+K DNLL+ KISDFG SRK YS+ D+ GT
Sbjct: 125 GLVSVHRLGYVHCDLKPDNLLVFPCRQSYELKISDFGSSRKVGE-YSDCWDVDLPFVGTP 183
Query: 1207 FWMAPEMVDTAHGYSAKVDIWSLGCVVLEMFAGKRPWS--NFEVVAAMFQIGKSKTAPPI 1264
+M+PE V + A +D+WSLGC+VLEM+ G PWS FE +A GK AP I
Sbjct: 184 VYMSPESVRSGVAEKA-LDLWSLGCIVLEMYTGVIPWSEVEFEDLAPALSKGK---APEI 239
Query: 1265 PDDTKDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPFCK--TSSSFDFPKTKL 1316
P K L A + FL+ CF +P+ R +A L+ H F + S F P KL
Sbjct: 240 P---KSLPCDA-RKFLETCFSRNPKERGSASDLLSHQFLRGEVVSGFSLPPLKL 289
>7300106 [T] KOG0690 Serine/threonine protein kinase
Length = 530
Score = 118 bits (296), Expect = 6e-26
Identities = 87/306 (28%), Positives = 149/306 (48%), Gaps = 27/306 (8%)
Query: 986 QEASEARKNEVSQKLQRKNTKMWGTKVVEITDKRTISINKSR------------NSRGEY 1033
Q+ +EA +N S+ + M ++ ++TD +I + NS G
Sbjct: 119 QQWTEAIRNVSSRLIDVGEVAMTPSEQTDMTDVDMATIAEDELSEQFSVQGTTCNSSGVK 178
Query: 1034 K----EFAWIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALK 1089
K F ++K ++GKG+FG V L T ++ A+K + +DE A ++ E+
Sbjct: 179 KVTLENFEFLK--VLGKGTFGKVILCREKATAKLYAIKILKKEVIIQKDEVAHTLTES-- 234
Query: 1090 SEVSTLKDLNHVNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQ 1149
LK NH ++ + N ++YV GG + + F + R +
Sbjct: 235 ---RVLKSTNHPFLISLKYSFQTNDRLCFVMQYVNGGELFWHLSHERIFTEDRTRFYGAE 291
Query: 1150 VLEGLAYLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWM 1209
++ L YLHS+GI++RD+K +NLLLD DG K++DFG+ K + Y + T GT ++
Sbjct: 292 IISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLC-KEDITYGRTTKTFCGTPEYL 350
Query: 1210 APEMVDTAHGYSAKVDIWSLGCVVLEMFAGKRPWSN--FEVVAAMFQIGKSKTAPPIPDD 1267
APE++D + Y VD W G V+ EM G+ P+ N +V+ + + + K I D+
Sbjct: 351 APEVLDD-NDYGQAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLILVEEVKFPRNITDE 409
Query: 1268 TKDLVS 1273
K+L++
Sbjct: 410 AKNLLA 415
>Hs19311016_1 [R] KOG0589 Serine/threonine protein kinase
Length = 330
Score = 118 bits (296), Expect = 6e-26
Identities = 77/275 (28%), Positives = 139/275 (50%), Gaps = 13/275 (4%)
Query: 1032 EYKEFAWIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSE 1091
E +E +I ++G+G+FG L ++ K+V + S ++ +AL +E
Sbjct: 46 EQEELHYIPIRVLGRGAFGEATLYRRTEDDSLVVWKEVDLTRLSEKERR-----DAL-NE 99
Query: 1092 VSTLKDLNHVNIVQYLGFEEKNGIYSLFLEYVAGGSV-GSLIRMYGR-FDDQLIRHLTKQ 1149
+ L L H NI+ Y N + LEY GG++ ++R + F+++++ Q
Sbjct: 100 IVILALLQHDNIIAYYNHFMDNTTLLIELEYCNGGNLYDKILRQKDKLFEEEMVVWYLFQ 159
Query: 1150 VLEGLAYLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWM 1209
++ ++ +H GILHRD+K N+ L + K+ D+G+++K N+ YS ++ T+ GT ++M
Sbjct: 160 IVSAVSCIHKAGILHRDIKTLNIFLTKANLIKLGDYGLAKKLNSEYSMAE-TLVGTPYYM 218
Query: 1210 APEMVDTAHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTK 1269
+PE+ Y+ K DIW++GCV+ E+ KR + + +I + A +
Sbjct: 219 SPELCQGVK-YNFKSDIWAVGCVIFELLTLKRTFDATNPLNLCVKIVQGIRAMEVDSSQY 277
Query: 1270 DLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPFCK 1304
L + C + DPE RPTAD L+ P +
Sbjct: 278 SLEL---IQMVHSCLDQDPEQRPTADELLDRPLLR 309
>YPL209c [D] KOG0580 Serine/threonine protein kinase
Length = 367
Score = 118 bits (295), Expect = 7e-26
Identities = 80/276 (28%), Positives = 138/276 (49%), Gaps = 28/276 (10%)
Query: 1041 GEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNH 1100
G+ +GKG FG VY + +TG + A+K + E + + + + EV LNH
Sbjct: 107 GKKLGKGKFGKVYCVRHRSTGYICALKVMEKEEIIKYN-----LQKQFRREVEIQTSLNH 161
Query: 1101 VNIVQYLG-FEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHS 1159
N+ + G F ++ +Y L +EY+ G + L+R++G F+D L Q+ L Y+H
Sbjct: 162 PNLTKSYGYFHDEKRVY-LLMEYLVNGEMYKLLRLHGPFNDILASDYIYQIANALDYMHK 220
Query: 1160 KGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVDTAHG 1219
K I+HRD+K +N+L+ + V K++DFG S N N T+ GT+ +++PEMV++
Sbjct: 221 KNIIHRDIKPENILIGFNNVIKLTDFGWS--IINPPENRRKTVCGTIDYLSPEMVESRE- 277
Query: 1220 YSAKVDIWSLGCVVLEMFAGKRPW------SNFEVVAAMFQIGKSKTAPPIPDDTKDLVS 1273
Y +D W+LG + E+ G P+ + ++ +AA+ K I D +DL+
Sbjct: 278 YDHTIDAWALGVLAFELLTGAPPFEEEMKDTTYKRIAAL----DIKMPSNISQDAQDLIL 333
Query: 1274 PAGQSFLDQCFEIDPEMRPTADSLVGHPFCKTSSSF 1309
+ + DP+ R + HP+ + F
Sbjct: 334 --------KLLKYDPKDRMRLGDVKMHPWILRNKPF 361
>Hs9845489 [R] KOG0586 Serine/threonine protein kinase
Length = 691
Score = 118 bits (295), Expect = 7e-26
Identities = 78/255 (30%), Positives = 129/255 (50%), Gaps = 14/255 (5%)
Query: 1044 IGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHVNI 1103
IGKG+F V LA ++ TG+ +AVK + + +S S ++ L EV +K LNH NI
Sbjct: 26 IGKGNFAKVKLARHILTGKEVAVKIIDKTQLNS------SSLQKLFREVRIMKVLNHPNI 79
Query: 1104 VQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHSKGIL 1163
V+ E L +EY +GG V + +GR ++ R +Q++ + Y H K I+
Sbjct: 80 VKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIV 139
Query: 1164 HRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVDTAHGYSAK 1223
HRD+KA+NLLLD D KI+DFG S + + N T G+ + APE+ +
Sbjct: 140 HRDLKAENLLLDADMNIKIADFGFSNEFT--FGNKLDTFCGSPPYAAPELFQGKKYDGPE 197
Query: 1224 VDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQSFLDQC 1283
VD+WSLG ++ + +G P+ + ++ + K P +S ++ L +
Sbjct: 198 VDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPF------YMSTDCENLLKKF 251
Query: 1284 FEIDPEMRPTADSLV 1298
++P R T + ++
Sbjct: 252 LILNPSKRGTLEQIM 266
>Hs9845487 [R] KOG0586 Serine/threonine protein kinase
Length = 745
Score = 118 bits (295), Expect = 7e-26
Identities = 78/255 (30%), Positives = 129/255 (50%), Gaps = 14/255 (5%)
Query: 1044 IGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHVNI 1103
IGKG+F V LA ++ TG+ +AVK + + +S S ++ L EV +K LNH NI
Sbjct: 26 IGKGNFAKVKLARHILTGKEVAVKIIDKTQLNS------SSLQKLFREVRIMKVLNHPNI 79
Query: 1104 VQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHSKGIL 1163
V+ E L +EY +GG V + +GR ++ R +Q++ + Y H K I+
Sbjct: 80 VKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIV 139
Query: 1164 HRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVDTAHGYSAK 1223
HRD+KA+NLLLD D KI+DFG S + + N T G+ + APE+ +
Sbjct: 140 HRDLKAENLLLDADMNIKIADFGFSNEFT--FGNKLDTFCGSPPYAAPELFQGKKYDGPE 197
Query: 1224 VDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQSFLDQC 1283
VD+WSLG ++ + +G P+ + ++ + K P +S ++ L +
Sbjct: 198 VDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPF------YMSTDCENLLKKF 251
Query: 1284 FEIDPEMRPTADSLV 1298
++P R T + ++
Sbjct: 252 LILNPSKRGTLEQIM 266
>Hs22062450 [R] KOG0586 Serine/threonine protein kinase
Length = 787
Score = 118 bits (295), Expect = 7e-26
Identities = 78/255 (30%), Positives = 129/255 (50%), Gaps = 14/255 (5%)
Query: 1044 IGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHVNI 1103
IGKG+F V LA ++ TG+ +AVK + + +S S ++ L EV +K LNH NI
Sbjct: 59 IGKGNFAKVKLARHILTGKEVAVKIIDKTQLNS------SSLQKLFREVRIMKVLNHPNI 112
Query: 1104 VQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHSKGIL 1163
V+ E L +EY +GG V + +GR ++ R +Q++ + Y H K I+
Sbjct: 113 VKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIV 172
Query: 1164 HRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVDTAHGYSAK 1223
HRD+KA+NLLLD D KI+DFG S + + N T G+ + APE+ +
Sbjct: 173 HRDLKAENLLLDADMNIKIADFGFSNEFT--FGNKLDTFCGSPPYAAPELFQGKKYDGPE 230
Query: 1224 VDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQSFLDQC 1283
VD+WSLG ++ + +G P+ + ++ + K P +S ++ L +
Sbjct: 231 VDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPF------YMSTDCENLLKKF 284
Query: 1284 FEIDPEMRPTADSLV 1298
++P R T + ++
Sbjct: 285 LILNPSKRGTLEQIM 299
>At3g51630 [R] KOG0584 Serine/threonine protein kinase
Length = 547
Score = 118 bits (295), Expect = 7e-26
Identities = 95/297 (31%), Positives = 142/297 (46%), Gaps = 28/297 (9%)
Query: 1031 GEYKEFAWIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKS 1090
G Y F E++GKG+ VY A + G +A QV + E E ++ L S
Sbjct: 20 GRYGRFR----EVLGKGAMKTVYKAFDQVLGMEVAWNQVKLNEVFRSPEP----LQRLYS 71
Query: 1091 EVSTLKDLNHVNIVQYLG--FEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTK 1148
EV LK+LNH +I++Y + ++ E G++ R Y + D + I+ +
Sbjct: 72 EVHLLKNLNHESIIRYCTSWIDVNRRTFNFITELFTSGTLREYRRKYQKVDIRAIKSWAR 131
Query: 1149 QVLEGLAYLHSKG--ILHRDMKADNLLLDND-GVCKISDFGIS---RKSNNIYSNSDMTM 1202
Q+L GLAYLH ++HRD+K DN+ ++ G KI D G++ R S N +S +
Sbjct: 132 QILNGLAYLHGHDPPVIHRDLKCDNIFVNGHLGQVKIGDLGLAAILRGSQNAHS-----V 186
Query: 1203 RGTVFWMAPEMVDTAHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAP 1262
GT +MAPE+ + Y+ VDI+S G VLEM G+ P+S A QI K T+
Sbjct: 187 IGTPEFMAPELYE--EDYNELVDIYSFGMCVLEMLTGEYPYSECTNPA---QIYKKVTSG 241
Query: 1263 PIPDDTKDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPFCKTSSSFDF-PKTKLAQ 1318
+PD + Q F+ +C E P A L+ PF + D P +L Q
Sbjct: 242 KLPDSFHLIQHTEAQRFVGKCLETVSRRLP-AKELLADPFLAATDERDLAPLFRLPQ 297
>YDR507c [D] KOG0588 Serine/threonine protein kinase
Length = 1142
Score = 117 bits (294), Expect = 9e-26
Identities = 86/313 (27%), Positives = 145/313 (45%), Gaps = 22/313 (7%)
Query: 1038 WIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEA---------L 1088
W GE +G GS G V LA N +TG+ AVK ++ F++ + S S+V + +
Sbjct: 19 WKLGETLGLGSTGKVQLARNGSTGQEAAVKVISKAVFNTGNVSGTSIVGSTTPDALPYGI 78
Query: 1089 KSEVSTLKDLNHVNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTK 1148
+ E+ +K LNH N+++ E N L LEY G + +L+ G + +
Sbjct: 79 EREIIIMKLLNHPNVLRLYDVWETNTDLYLVLEYAEKGELFNLLVERGPLPEHEAIRFFR 138
Query: 1149 QVLEGLAYLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFW 1208
Q++ G++Y H+ GI+HRD+K +NLLLD+ KI+DFG++ T G+ +
Sbjct: 139 QIIIGVSYCHALGIVHRDLKPENLLLDHKYNIKIADFGMAALETE--GKLLETSCGSPHY 196
Query: 1209 MAPEMVDTAHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDT 1268
APE+V D+WS G ++ + G+ P+ + + K +P D
Sbjct: 197 AAPEIVSGIPYQGFASDVWSCGVILFALLTGRLPFDEEDGNIRTLLLKVQKGEFEMPSD- 255
Query: 1269 KDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPFCKTSSSFDFPK---------TKLAQF 1319
D +S Q + + +DPE R ++ HP + S K T L
Sbjct: 256 -DEISREAQDLIRKILTVDPERRIKTRDILKHPLLQKYPSIRDSKSIRGLPREDTYLTPL 314
Query: 1320 IKSNDKLNSSRLR 1332
+SN ++++ L+
Sbjct: 315 SESNSSIDATILQ 327
>SPBC4F6.06 [T] KOG0583 Serine/threonine protein kinase
Length = 891
Score = 117 bits (294), Expect = 9e-26
Identities = 81/282 (28%), Positives = 135/282 (47%), Gaps = 29/282 (10%)
Query: 1038 WIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKS------- 1090
++ G+ IG GS G V +A ++ TGE A+K VT A + EA K+
Sbjct: 125 YVLGKTIGAGSMGKVKVAHHLKTGEQFAIKIVTRLHPDITKAKAAASAEATKAAQSEKNK 184
Query: 1091 EVSTLKD------LNHVNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIR 1144
E+ T+++ L H I + N Y + E+V GG + I +G+ ++ R
Sbjct: 185 EIRTVREAALSTLLRHPYICEARDVYITNSHYYMVFEFVDGGQMLDYIISHGKLKEKQAR 244
Query: 1145 HLTKQVLEGLAYLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSD--MTM 1202
+Q+ L+YLH ++HRD+K +N+L+ G KI DFG+S N+Y T
Sbjct: 245 KFVRQIGSALSYLHQNSVVHRDLKIENILISKTGDIKIIDFGLS----NLYRRQSRLRTF 300
Query: 1203 RGTVFWMAPEMVDTAHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAP 1262
G++++ APE+++ +VD+WS G V+ + GK P+ + + A +I K
Sbjct: 301 CGSLYFAAPELLNAQPYIGPEVDVWSFGIVLYVLVCGKVPFDDQNMSALHAKIKKGTVEY 360
Query: 1263 P--IPDDTKDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPF 1302
P + D K L+S + DP R T + ++ HP+
Sbjct: 361 PSYLSSDCKGLLS--------RMLVTDPLKRATLEEVLNHPW 394
>Hs14110390 [D] KOG0600 Cdc2-related protein kinase
Length = 1452
Score = 117 bits (294), Expect = 9e-26
Identities = 153/639 (23%), Positives = 249/639 (38%), Gaps = 89/639 (13%)
Query: 655 APKRKAPKPPVNGNPVTSGSLPSAAAKNVSESPLESPPKLDRNGKTIYQKNKPRPPPPLT 714
A +R+ P+ G + S ++ + +SP SP G + Y + PR P P +
Sbjct: 309 AYRRRRSLSPLGGRDDSPVSHRASQSLRSRKSP--SPAG---GGSSPYSRRLPRSPSPYS 363
Query: 715 TEXXXXXXXXXXXXQDLNEVKESPVQSFTPASTQVMVPQPYKGALETLKPRKSSADLSIR 774
+ +V SP S + ++ PY L R+S S
Sbjct: 364 RRRSPSYSRHSSYERG-GDVSPSPYSSSSWRRSR----SPYSPVL-----RRSGKSRSRS 413
Query: 775 PRMSLRQFSRSNSSLNRKVLSTSRQTLNRTNSKPLVTSSTAADIFDENDISFADAPELXX 834
P S SRS L+R S SR + + + S + SS AA++ A+A
Sbjct: 414 PYSSRHSRSRSRHRLSR---SRSRHS-SISPSTLTLKSSLAAELNKNKKARAAEAARAAE 469
Query: 835 XXXXXXXXXEIIWSRDRKSISNDVPEFSFNTEDTIDLVGTDTTQVSVGATEGSDTPKKMA 894
+ SN NTE T S T KK+
Sbjct: 470 AAKAAEATKAAEAAAKAAKASNTSTPTKGNTE----------TSASASQTNHVKDVKKIK 519
Query: 895 LR--PSPD---VVYQNLEKFFPDADL---DNPILEGLTXXXXXXXXXXXXXXRGFEKSLK 946
+ PSP + + K P + +N ++ E+S+
Sbjct: 520 IEHAPSPSSGGTLKNDKAKTKPPLQVTKVENNLIVDKATKKAVIVGKESKSAATKEESVS 579
Query: 947 TKSEQQPAFLS-SRGESSQFLTPVKSLKPPKRTKTIRIIAQEASEAR--------KNEVS 997
K + +P S E Q + V S PP + +EA R K EV
Sbjct: 580 LKEKTKPLTPSIGAKEKEQHVALVTSTLPPLPLPPMLPEDKEADSLRGNISVKAVKKEVE 639
Query: 998 QKLQ------------------RKNTKMWGTKVVEITDKRTISINKSRNSRGEYKEFAWI 1039
+KL+ K+ + T ++ KR I R + K+ W
Sbjct: 640 KKLRCLLADLPLPPELPGGDDLSKSPEEKKT-TTQLHSKRRPKICGPRYGETKEKDIDWG 698
Query: 1040 KG--------EIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSE 1091
K IIG+G++G VY A + TGEM+A+K+V + +E + A++ E
Sbjct: 699 KLCVDKFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRL-----DNEKEGFPITAIR-E 752
Query: 1092 VSTLKDLNHVNIVQY----------LGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQ 1141
+ L+ L H +I+ L F++ G + L EY+ +G L F++
Sbjct: 753 IKILRQLTHQSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNEN 812
Query: 1142 LIRHLTKQVLEGLAYLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMT 1201
I+ +Q++EGL Y H K LHRD+K N+LL+N G K++DFG++R ++ S
Sbjct: 813 HIKSFMRQLMEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRPYTN 872
Query: 1202 MRGTVFWMAPEMVDTAHGYSAKVDIWSLGCVVLEMFAGK 1240
T+++ PE++ Y+ +D+WS GC++ E+F K
Sbjct: 873 KVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKK 911
>Hs14110387 [D] KOG0600 Cdc2-related protein kinase
Length = 1512
Score = 117 bits (294), Expect = 9e-26
Identities = 153/639 (23%), Positives = 249/639 (38%), Gaps = 89/639 (13%)
Query: 655 APKRKAPKPPVNGNPVTSGSLPSAAAKNVSESPLESPPKLDRNGKTIYQKNKPRPPPPLT 714
A +R+ P+ G + S ++ + +SP SP G + Y + PR P P +
Sbjct: 309 AYRRRRSLSPLGGRDDSPVSHRASQSLRSRKSP--SPAG---GGSSPYSRRLPRSPSPYS 363
Query: 715 TEXXXXXXXXXXXXQDLNEVKESPVQSFTPASTQVMVPQPYKGALETLKPRKSSADLSIR 774
+ +V SP S + ++ PY L R+S S
Sbjct: 364 RRRSPSYSRHSSYERG-GDVSPSPYSSSSWRRSR----SPYSPVL-----RRSGKSRSRS 413
Query: 775 PRMSLRQFSRSNSSLNRKVLSTSRQTLNRTNSKPLVTSSTAADIFDENDISFADAPELXX 834
P S SRS L+R S SR + + + S + SS AA++ A+A
Sbjct: 414 PYSSRHSRSRSRHRLSR---SRSRHS-SISPSTLTLKSSLAAELNKNKKARAAEAARAAE 469
Query: 835 XXXXXXXXXEIIWSRDRKSISNDVPEFSFNTEDTIDLVGTDTTQVSVGATEGSDTPKKMA 894
+ SN NTE T S T KK+
Sbjct: 470 AAKAAEATKAAEAAAKAAKASNTSTPTKGNTE----------TSASASQTNHVKDVKKIK 519
Query: 895 LR--PSPD---VVYQNLEKFFPDADL---DNPILEGLTXXXXXXXXXXXXXXRGFEKSLK 946
+ PSP + + K P + +N ++ E+S+
Sbjct: 520 IEHAPSPSSGGTLKNDKAKTKPPLQVTKVENNLIVDKATKKAVIVGKESKSAATKEESVS 579
Query: 947 TKSEQQPAFLS-SRGESSQFLTPVKSLKPPKRTKTIRIIAQEASEAR--------KNEVS 997
K + +P S E Q + V S PP + +EA R K EV
Sbjct: 580 LKEKTKPLTPSIGAKEKEQHVALVTSTLPPLPLPPMLPEDKEADSLRGNISVKAVKKEVE 639
Query: 998 QKLQ------------------RKNTKMWGTKVVEITDKRTISINKSRNSRGEYKEFAWI 1039
+KL+ K+ + T ++ KR I R + K+ W
Sbjct: 640 KKLRCLLADLPLPPELPGGDDLSKSPEEKKT-TTQLHSKRRPKICGPRYGETKEKDIDWG 698
Query: 1040 KG--------EIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSE 1091
K IIG+G++G VY A + TGEM+A+K+V + +E + A++ E
Sbjct: 699 KLCVDKFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRL-----DNEKEGFPITAIR-E 752
Query: 1092 VSTLKDLNHVNIVQY----------LGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQ 1141
+ L+ L H +I+ L F++ G + L EY+ +G L F++
Sbjct: 753 IKILRQLTHQSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNEN 812
Query: 1142 LIRHLTKQVLEGLAYLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMT 1201
I+ +Q++EGL Y H K LHRD+K N+LL+N G K++DFG++R ++ S
Sbjct: 813 HIKSFMRQLMEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRPYTN 872
Query: 1202 MRGTVFWMAPEMVDTAHGYSAKVDIWSLGCVVLEMFAGK 1240
T+++ PE++ Y+ +D+WS GC++ E+F K
Sbjct: 873 KVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKK 911
>At2g26980 [T] KOG0583 Serine/threonine protein kinase
Length = 441
Score = 117 bits (294), Expect = 9e-26
Identities = 76/226 (33%), Positives = 120/226 (52%), Gaps = 9/226 (3%)
Query: 1041 GEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNH 1100
G IG+G+F V A N TGE +A+K + + M E ++ E++T+K + H
Sbjct: 17 GRTIGEGTFAKVKFARNSETGEPVALKILDKEKVLKH-----KMAEQIRREIATMKLIKH 71
Query: 1101 VNIVQ-YLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHS 1159
N+VQ Y K I+ + LEYV GG + I GR + R +Q++ + Y HS
Sbjct: 72 PNVVQLYEVMASKTKIF-IILEYVTGGELFDKIVNDGRMKEDEARRYFQQLIHAVDYCHS 130
Query: 1160 KGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDM-TMRGTVFWMAPEMVDTAH 1218
+G+ HRD+K +NLLLD+ G KISDFG+S S + + + T GT ++APE+++
Sbjct: 131 RGVYHRDLKPENLLLDSYGNLKISDFGLSALSQQVRDDGLLHTSCGTPNYVAPEVLNDRG 190
Query: 1219 GYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSK-TAPP 1263
A D+WS G V+ + AG P+ + ++ +I + PP
Sbjct: 191 YDGATADMWSCGVVLYVLLAGYLPFDDSNLMNLYKKISSGEFNCPP 236
>Hs4507277_1 [R] KOG0589 Serine/threonine protein kinase
Length = 292
Score = 117 bits (294), Expect = 9e-26
Identities = 86/292 (29%), Positives = 145/292 (49%), Gaps = 19/292 (6%)
Query: 1043 IIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHVN 1102
++GKGS+G V L + G+ +K++ + SS++ A + E L L H N
Sbjct: 11 VVGKGSYGEVTLVKHRRDGKQYVIKKLNLRNASSRER------RAAEQEAQLLSQLKHPN 64
Query: 1103 IVQYL-GFEEKNGIYSLFLEYVAGGSV-GSLIRMYGRF--DDQLIRHLTKQVLEGLAYLH 1158
IV Y +E +G+ + + + GG + L G+ ++Q++ Q+ L YLH
Sbjct: 65 IVTYKESWEGGDGLLYIVMGFCEGGDLYRKLKEQKGQLLPENQVVEWFV-QIAMALQYLH 123
Query: 1159 SKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVDTAH 1218
K ILHRD+K N+ L + K+ D GI+R N + + T+ GT ++M+PE+
Sbjct: 124 EKHILHRDLKTQNVFLTRTNIIKVGDLGIARVLEN-HCDMASTLIGTPYYMSPELFSN-K 181
Query: 1219 GYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQS 1278
Y+ K D+W+LGC V EM K ++ ++ + +++I + K P +P D SP
Sbjct: 182 PYNYKSDVWALGCCVYEMATLKHAFNAKDMNSLVYRIIEGK-LPAMPRD----YSPELAE 236
Query: 1279 FLDQCFEIDPEMRPTADSLVGHPFCKTSSSFDFPKTKLAQFIKSNDKLNSSR 1330
+ PE RP+ S++ P+ K SF TK+ + K+N K S+
Sbjct: 237 LIRTMLSKRPEERPSVRSILRQPYIKRQISFFLEATKI-KTSKNNIKNGDSQ 287
>At1g18160 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 990
Score = 117 bits (293), Expect = 1e-25
Identities = 82/255 (32%), Positives = 131/255 (51%), Gaps = 17/255 (6%)
Query: 1042 EIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHV 1101
E IG GS+G VY G +AVK+ F QD + ++ E +SEV ++ L H
Sbjct: 717 ERIGLGSYGEVYRG--DWHGTAVAVKK-----FIDQDITGEAL-EEFRSEVRMMRRLRHP 768
Query: 1102 NIVQYLGFEEKNGIYSLFLEYVAGGSVGSLI-RMYGRFDDQLIRHLTKQVLEGLAYLHSK 1160
NIV ++G + S+ E++ GS+ LI R + D++ + G+ YLHS
Sbjct: 769 NIVLFMGAVTRPPNLSIVTEFLPRGSLYRLIHRPNNQLDERKRLRMALDAARGMNYLHSC 828
Query: 1161 G--ILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVDTAH 1218
I+HRD+K+ NLL+D + V K+ DFG+SR + Y +S T GT WMAPE++
Sbjct: 829 NPVIVHRDLKSPNLLVDKNWVVKVCDFGLSRMKVSTYLSSKST-AGTAEWMAPEVLRNEP 887
Query: 1219 GYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQS 1278
K D++S G ++ E+F ++PW + + +G IP + V P
Sbjct: 888 A-DEKCDVYSYGVILWELFTLQQPWGKMNPMQVVGAVGFQHRRLDIP----EFVDPGIAD 942
Query: 1279 FLDQCFEIDPEMRPT 1293
+ +C++ DP +RP+
Sbjct: 943 IIRKCWQTDPRLRPS 957
>Hs21361433 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 970
Score = 117 bits (292), Expect = 2e-25
Identities = 88/301 (29%), Positives = 149/301 (49%), Gaps = 29/301 (9%)
Query: 1041 GEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAI---SMVEALKSEVSTLKD 1097
G ++GKGSF VY A ++ +G +A+K + D+ A+ MV+ +++EV
Sbjct: 15 GNLLGKGSFAGVYRAESIHSGLEVAIKMI--------DKKAMYKAGMVQRVQNEVKIHCQ 66
Query: 1098 LNHVNIVQ-YLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGR-FDDQLIRHLTKQVLEGLA 1155
L H +I++ Y FE+ N +Y L LE G + ++ + F + RH Q++ G+
Sbjct: 67 LKHPSILELYNYFEDSNYVY-LVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQIITGML 125
Query: 1156 YLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVD 1215
YLHS GILHRD+ NLLL + KI+DFG++ + + T+ GT +++PE+
Sbjct: 126 YLHSHGILHRDLTLSNLLLTRNMNIKIADFGLATQL-KMPHEKHYTLCGTPNYISPEIAT 184
Query: 1216 -TAHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSP 1274
+AHG + D+WSLGC+ + G+ P+ V + ++ + P +S
Sbjct: 185 RSAHGLES--DVWSLGCMFYTLLIGRPPFDTDTVKNTLNKVVLADYEMP------TFLSI 236
Query: 1275 AGQSFLDQCFEIDPEMRPTADSLVGHPFCKTSSSFDFPKTKLAQFIKSNDKLNSSRLRIS 1334
+ + Q +P R + S++ HPF +SS TK D ++S IS
Sbjct: 237 EAKDLIHQLLRRNPADRLSLSSVLDHPFMSRNSS-----TKSKDLGTVEDSIDSGHATIS 291
Query: 1335 S 1335
+
Sbjct: 292 T 292
>CE20564 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 540
Score = 117 bits (292), Expect = 2e-25
Identities = 109/457 (23%), Positives = 195/457 (41%), Gaps = 35/457 (7%)
Query: 852 KSISNDVPEFSFNTEDTIDLVGTDTTQVSVGATEGSDTPKKMALRPSPDVVYQNLEKFFP 911
+SIS P + +D+ T + S P M P P V N +
Sbjct: 72 RSISRPKPMVDPSCITPVDVAELKTVIRGPSSRYNSPLPFGMTNSPMPSVARSNSLRISA 131
Query: 912 DADLDNPILEGLTXXXXXXXXXXXXXXRGFEKS------LKTKSEQQPAFLSSRGESSQF 965
A +P++ + RG+ + L ++++ P + E
Sbjct: 132 TA---SPVVNVSSARHSFRPTLPPVSQRGYPFNDPSYAPLPLRNQKPPMSTTFGVEKPHQ 188
Query: 966 LTPVKSLKPPKRTKTIRIIAQEASEARKNEVSQKLQRKNTKMWGTKVVEITDKRTISINK 1025
+ ++ P RT T ++ + S + + + Q K T+ + K +
Sbjct: 189 YQQIITIVAPSRTTTPQLQPKSPSTPQ----AMRQQPKCTEGVSDEEFRNALKFVVDGTD 244
Query: 1026 SRNSRGEYKEFAWIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMV 1085
R+ +YK+ IG+GS G V A ++T +++AVK++ + + +
Sbjct: 245 PRSDLTDYKQ--------IGEGSTGVVEAAYKISTKQIVAVKRMNLRKQQRR-------- 288
Query: 1086 EALKSEVSTLKDLNHVNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRH 1145
E L +EVS L+ H NIV++ + + +E++ GGS+ ++ R + I
Sbjct: 289 ELLFNEVSILRQYQHPNIVRFFSSHLVDDELWVVMEFMEGGSLTDIVTAT-RMTEPQIAT 347
Query: 1146 LTKQVLEGLAYLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGT 1205
+++QVL L +LH++ ++HRD+K+D++LL DG K++DFG + + ++ GT
Sbjct: 348 ISRQVLGALDFLHARKVIHRDIKSDSILLKRDGTVKLTDFGFCGQLSEEVPRR-RSLVGT 406
Query: 1206 VFWMAPEMVDTAHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIP 1265
+W A E++ Y + DIWS G +++EM G+ P+ N + AM +I A
Sbjct: 407 PYWTAAEVI-AREPYDTRADIWSFGIMLIEMVEGEPPFFNDQPFQAMKRIRDEHEA---R 462
Query: 1266 DDTKDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPF 1302
VS L C D R A L+ HPF
Sbjct: 463 FSRHAKVSVELSELLSHCIVKDVNKRWPAKDLLRHPF 499
>CE01405 [T] KOG0577 Serine/threonine protein kinase
Length = 982
Score = 117 bits (292), Expect = 2e-25
Identities = 84/272 (30%), Positives = 133/272 (48%), Gaps = 16/272 (5%)
Query: 1044 IGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHVNI 1103
IG GSFGAVY A + + +A+K++ FS + A+ + EVS L + H +I
Sbjct: 36 IGHGSFGAVYFAYDKKNEQTVAIKKMN---FSGKQ--AVEKWNDILKEVSFLNTVVHPHI 90
Query: 1104 VQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHSKGIL 1163
V Y K+ L +EY G + + + + I + Q L+ L YLHS +
Sbjct: 91 VDYKACFLKDTTCWLVMEYCIGSAADIVDVLRKGMREVEIAAICSQTLDALRYLHSLKRI 150
Query: 1164 HRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMV---DTAHGY 1220
HRD+KA N+LL + + K++DFG + + T GT F+MAPE++ D H Y
Sbjct: 151 HRDIKAGNILLSDHAIVKLADFGSAS-----LVDPAQTFIGTPFFMAPEVILAMDEGH-Y 204
Query: 1221 SAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKS--KTAPPIPDDTKDLVSPAGQS 1278
+ + DIWSLG +E+ + P + ++A++ I ++ T PI + S
Sbjct: 205 TDRADIWSLGITCIELAERRPPLFSMNAMSALYHIAQNDPPTLSPIDTSEQPEWSLEFVQ 264
Query: 1279 FLDQCFEIDPEMRPTADSLVGHPFCKTSSSFD 1310
F+D+C E R +A+ HPF + S D
Sbjct: 265 FIDKCLRKPAEERMSAEECFRHPFIQRSRPSD 296
>At4g30960 [T] KOG0583 Serine/threonine protein kinase
Length = 441
Score = 117 bits (292), Expect = 2e-25
Identities = 78/272 (28%), Positives = 144/272 (52%), Gaps = 19/272 (6%)
Query: 1041 GEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNH 1100
G ++G G+F VY A N+ TG+ +A+K V + + MV+ +K E+S ++ + H
Sbjct: 27 GRLLGHGTFAKVYHARNIQTGKSVAMKVV-----GKEKVVKVGMVDQIKREISVMRMVKH 81
Query: 1101 VNIVQ-YLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHS 1159
NIV+ + K+ IY +E V GG + + + GR + + R +Q++ + + HS
Sbjct: 82 PNIVELHEVMASKSKIY-FAMELVRGGELFAKVAK-GRLREDVARVYFQQLISAVDFCHS 139
Query: 1160 KGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDM-TMRGTVFWMAPEMVDTAH 1218
+G+ HRD+K +NLLLD +G K++DFG+S + ++ + + T GT ++APE++
Sbjct: 140 RGVYHRDLKPENLLLDEEGNLKVTDFGLSAFTEHLKQDGLLHTTCGTPAYVAPEVILKKG 199
Query: 1219 GYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQI--GKSKTAPPIPDDTKDLVSPAG 1276
AK D+WS G ++ + AG P+ + +V +I G K + D + LV+
Sbjct: 200 YDGAKADLWSCGVILFVLLAGYLPFQDDNLVNMYRKIYRGDFKCPGWLSSDARRLVT--- 256
Query: 1277 QSFLDQCFEIDPEMRPTADSLVGHPFCKTSSS 1308
+ + +P R T + ++ P+ K ++
Sbjct: 257 -----KLLDPNPNTRITIEKVMDSPWFKKQAT 283
>At3g24720 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 297
Score = 117 bits (292), Expect = 2e-25
Identities = 76/258 (29%), Positives = 134/258 (51%), Gaps = 18/258 (6%)
Query: 1044 IGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHVNI 1103
+G G++G VY G +A+K++ F+ + + + E L +L+H N+
Sbjct: 22 LGSGTYGTVYHG--TWRGTDVAIKRIRNSCFAGRSSEQERLTKDFWREAQILSNLHHPNV 79
Query: 1104 VQYLGF--EEKNGIYSLFLEYVAGGSVG-SLIRMYGRFDDQLIRHLTKQVLEGLAYLHSK 1160
V + G + G + E++ GS+ +L++ D + + G+ YLHSK
Sbjct: 80 VAFYGIVPDGTGGTLATVTEFMVNGSLRHALLKKDRLLDTRKKIIIAMDAAFGMEYLHSK 139
Query: 1161 GILHRDMKADNLLLD----NDGVCKISDFGISR-KSNNIYSNSDMTMRGTVFWMAPEMVD 1215
I+H D+K +NLL++ +CK+ D G+SR K N + S +RGT+ WMAPE+++
Sbjct: 140 NIVHFDLKCENLLVNLRDPQRPICKVGDLGLSRIKRNTLVSGG---VRGTLPWMAPELLN 196
Query: 1216 -TAHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSP 1274
++ S KVD++S G + E+ G+ P+++ A + I K+ PPIP SP
Sbjct: 197 GSSTRVSEKVDVFSYGISLWEILTGEEPYADMHCGAIIGGIVKNTLRPPIPKS----CSP 252
Query: 1275 AGQSFLDQCFEIDPEMRP 1292
+ ++QC+ +DP+ RP
Sbjct: 253 EWKKLMEQCWSVDPDSRP 270
>At3g06640 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 763
Score = 117 bits (292), Expect = 2e-25
Identities = 80/261 (30%), Positives = 135/261 (51%), Gaps = 17/261 (6%)
Query: 1041 GEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNH 1100
GE IG+GS G VY L G +AVK ++ E+S + ++++ + EVS ++ L H
Sbjct: 449 GEQIGQGSCGTVYHGL--WFGSDVAVKLISKQEYSEE------VIQSFRQEVSLMQRLRH 500
Query: 1101 VNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLI-RMYGRFDDQLIRHLTKQVLEGLAYLH- 1158
N++ ++G + E++ GS+ L+ R + D + ++ + G+ YLH
Sbjct: 501 PNVLLFMGAVTLPQGLCIVSEFLPRGSLFRLLQRNMSKLDWRRRINMALDIARGMNYLHR 560
Query: 1159 -SKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVDTA 1217
S I+HRD+K+ NLL+D + K++DFG+SR ++ Y S + +G WMAPE++
Sbjct: 561 CSPPIIHRDLKSSNLLVDKNLTVKVADFGLSRIKHHTYLTS-KSGKGMPQWMAPEVLRN- 618
Query: 1218 HGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQ 1277
K DI+S G V+ E+ K PW N + + +G IP D + P
Sbjct: 619 ESADEKSDIYSFGVVLWELATEKIPWENLNSMQVIGAVGFMNQRLEIPKD----IDPDWI 674
Query: 1278 SFLDQCFEIDPEMRPTADSLV 1298
S ++ C+ D ++RPT L+
Sbjct: 675 SLIESCWHRDAKLRPTFQELM 695
>7296451 [D] KOG0600 Cdc2-related protein kinase
Length = 1157
Score = 117 bits (292), Expect = 2e-25
Identities = 93/364 (25%), Positives = 170/364 (46%), Gaps = 60/364 (16%)
Query: 1016 TDKRTISINKSRNSRGEYKEFAWIKGEI------IGKGSFGAVYLALNVTTGEMLAVKQV 1069
T +R + +N+ R+SR +++ ++ IG+G++G VY A + T +M+A+K+V
Sbjct: 777 TRQRPVILNR-RDSRNNVRDWGERCVDVFEMIAQIGEGTYGQVYKARDHHTNDMVALKKV 835
Query: 1070 TVPEFSSQDESAISMVEALKSEVSTLKDLNHVNIVQY----------LGFEEKNGIYSLF 1119
+ + E + A++ E+ L+ LNH NIV + F + G + L
Sbjct: 836 RL-----EHEKEGFPITAVR-EIKILRQLNHRNIVNLHEIVTDKQDAVEFRKDKGSFYLV 889
Query: 1120 LEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHSKGILHRDMKADNLLLDNDGV 1179
EY+ +G L F+++ + KQ+L+GL Y H K LHRD+K N+L++N G
Sbjct: 890 FEYMDHDLMGLLESGMVDFNEENNASIMKQLLDGLNYCHKKNFLHRDIKCSNILMNNRGK 949
Query: 1180 CKISDFGISRKSN-----NIYSNSDMTMRGTVFWMAPEMVDTAHGYSAKVDIWSLGCVVL 1234
K++DFG++R N Y+N +T+ ++ PE++ Y +D+WS GC++
Sbjct: 950 VKLADFGLARLYNADDRERPYTNKVITL----WYRPPELLLGEERYGPSIDVWSCGCILG 1005
Query: 1235 EMFAGKRPWSNFEVVAAMFQIGKSKTAPPIP--------------------------DDT 1268
E+F KRP A + P+P +D
Sbjct: 1006 ELFV-KRPLFQANAEMAQLETISKICGSPVPAVWPNVIKLPLFHTLKQKKTHRRRLREDF 1064
Query: 1269 KDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPFCKTSSSFDFPKTKLAQFIKSNDKLNS 1328
+ + +PA LD+ ++DP+ R TA+ + P+ + + + P +L + ++ +
Sbjct: 1065 EFMPAPA-LDLLDKMLDLDPDKRITAEDALRSPWLRKINPDEMPTPQLPTWQDCHELWSK 1123
Query: 1329 SRLR 1332
R R
Sbjct: 1124 KRRR 1127
>At3g46920_2 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 505
Score = 117 bits (292), Expect = 2e-25
Identities = 78/264 (29%), Positives = 137/264 (51%), Gaps = 18/264 (6%)
Query: 1044 IGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHVNI 1103
+G G+FG VY G +A+K++ F+ + M++ +E L L+H N+
Sbjct: 228 LGSGTFGTVYHGK--WRGTDVAIKRINDRCFAGKPSEQERMIDDFWNEAQNLAGLHHPNV 285
Query: 1104 VQYLG--FEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHL-TKQVLEGLAYLHSK 1160
V + G + G + EY+ GS+ + ++ R D+ R L + G+ YLH K
Sbjct: 286 VAFYGVVLDSPGGSVATVTEYMVNGSLRNALQKNVRNFDRCKRQLIAMDIAFGMEYLHGK 345
Query: 1161 GILHRDMKADNLLLD----NDGVCKISDFGISR-KSNNIYSNSDMTMRGTVFWMAPEMVD 1215
I+H D+K+DNLL++ + +CK+ D G+S+ K + S +RGT+ WMAPE+++
Sbjct: 346 KIVHFDLKSDNLLVNLRDPHRPICKVGDLGLSKVKCQTLISGG---VRGTLPWMAPELLN 402
Query: 1216 -TAHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSP 1274
T+ S KVD++S G V+ E+F G+ P+++ A + I + P IP D
Sbjct: 403 GTSSLVSEKVDVFSFGIVLWELFTGEEPYADLHYGAIIGGIVSNTLRPQIP----DFCDM 458
Query: 1275 AGQSFLDQCFEIDPEMRPTADSLV 1298
+ +++C+ +P RP+ +V
Sbjct: 459 DWKLLMERCWSAEPSERPSFTEIV 482
>YKL139w [D] KOG0600 Cdc2-related protein kinase
Length = 528
Score = 116 bits (291), Expect = 2e-25
Identities = 84/298 (28%), Positives = 144/298 (48%), Gaps = 29/298 (9%)
Query: 947 TKSEQQPAFLSSRGESSQFLTPVKSLKPPKRTKTIRIIAQEASEARKNEVSQKLQRKNTK 1006
T E +P + ++FL+ + PK K++ S N++ +K
Sbjct: 100 TSYENRPKSIKRDETKAEFLSHL-----PKGPKSVEKSRYNNSSNTSNDIKNGYHA--SK 152
Query: 1007 MWGTKVVE----ITDKRTISINKSRNSRGEYKEFAWIKGEIIGKGSFGAVYLALNVTTGE 1062
+ K E I K +S+ + S Y + G+G++G VY A N T +
Sbjct: 153 YYNHKGQEGRSVIAKKVPVSVLTQQRSTSVYLRIMQV-----GEGTYGKVYKAKNTNTEK 207
Query: 1063 MLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHVNI--VQYLGFEEKNGIYSLFL 1120
++A+K++ + Q E + +++ E+ L+ +H N+ ++ + E + +Y +F
Sbjct: 208 LVALKKLRL-----QGEREGFPITSIR-EIKLLQSFDHPNVSTIKEIMVESQKTVYMIF- 260
Query: 1121 EYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHSKGILHRDMKADNLLLDNDGVC 1180
EY G L+ + +HL KQ+L G+ YLH ILHRD+K N+L+DN G
Sbjct: 261 EYADNDLSGLLLNKEVQISHSQCKHLFKQLLLGMEYLHDNKILHRDVKGSNILIDNQGNL 320
Query: 1181 KISDFGISRKSNNIYSNSDMTMRGTVFW-MAPEMVDTAHGYSAKVDIWSLGCVVLEMF 1237
KI+DFG++RK N S +D T R W PE++ Y +VD+W GC+++E+F
Sbjct: 321 KITDFGLARKMN---SRADYTNRVITLWYRPPELLLGTTNYGTEVDMWGCGCLLVELF 375
>At3g08730 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 465
Score = 116 bits (291), Expect = 2e-25
Identities = 70/204 (34%), Positives = 116/204 (56%), Gaps = 12/204 (5%)
Query: 1042 EIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHV 1101
+++GKG+FG VY T E+ A+K + ++ + E +K+E L ++H
Sbjct: 138 KVVGKGAFGKVYQVRKKETSEIYAMKVMRKDHIMEKNHA-----EYMKAERDILTKIDHP 192
Query: 1102 NIVQY-LGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHSK 1160
IVQ F+ K +Y L L+++ GG + + G F + L R T +++ +++LH K
Sbjct: 193 FIVQLKYSFQTKYRLY-LVLDFINGGHLFFQLYHQGLFREDLARVYTAEIVSAVSHLHEK 251
Query: 1161 GILHRDMKADNLLLDNDGVCKISDFGISRK-SNNIYSNSDMTMRGTVFWMAPEMVDTAHG 1219
GI+HRD+K +N+L+D DG ++DFG++++ N SNS M GT +MAPE+V G
Sbjct: 252 GIMHRDLKPENILMDTDGHVMLTDFGLAKEFEENTRSNS---MCGTTEYMAPEIV-RGKG 307
Query: 1220 YSAKVDIWSLGCVVLEMFAGKRPW 1243
+ D WS+G ++ EM GK P+
Sbjct: 308 HDKAADWWSVGILLYEMLTGKPPF 331
>7293761 [T] KOG4721 Serine/threonine protein kinase contains leucine zipper
domain
Length = 977
Score = 116 bits (291), Expect = 2e-25
Identities = 77/260 (29%), Positives = 135/260 (51%), Gaps = 26/260 (10%)
Query: 1042 EIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHV 1101
E +G G+ GAV+ E +AVK+V E ++++ L+ L+H
Sbjct: 165 EWLGSGAQGAVFSGR--LKNETVAVKKVK---------------ELKETDIKHLRKLDHE 207
Query: 1102 NIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHSKG 1161
NI+++ G ++ ++ + +E+ G + ++++ + +KQ+ G+ YLHS
Sbjct: 208 NIIKFKGVCTQSPVFCIIMEFCPYGPLQNILKEEQVMLPSRLVSWSKQIALGMQYLHSHK 267
Query: 1162 ILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVDTAHGYS 1221
I+HRD+K+ N+L+ + V KISDFG SR+ N I ++ M+ GTV WMAPE++ S
Sbjct: 268 IIHRDLKSPNILISTNEVVKISDFGTSREWNEI--STKMSFAGTVAWMAPEVIRN-EPCS 324
Query: 1222 AKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQSFLD 1281
KVDIWS G V+ EM + P+ + + A ++ +G + +P P G L
Sbjct: 325 EKVDIWSYGVVLWEMLTCEIPYKDVDSSAIIWGVGNNSLKLLVPS-----TCPEGFKLLV 379
Query: 1282 Q-CFEIDPEMRPTADSLVGH 1300
+ C++ P RP+ ++ H
Sbjct: 380 KLCWKSKPRNRPSFRQILSH 399
>YCL024w [T] KOG0583 Serine/threonine protein kinase
Length = 1037
Score = 116 bits (290), Expect = 3e-25
Identities = 88/310 (28%), Positives = 154/310 (49%), Gaps = 28/310 (9%)
Query: 1038 WIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFS-----SQDESAISMVEALKSEV 1092
W GE +G GS G V LA + TG AVK ++ F+ S D+S + ++ E+
Sbjct: 21 WKLGETLGFGSTGKVQLAQHERTGHRTAVKVISKSIFNNNGNHSNDDSVLPY--NIEREI 78
Query: 1093 STLKDLNHVNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLE 1152
+K L+H N++ E N L LEY G + +L+ +G ++ + +Q++
Sbjct: 79 VIMKLLSHPNVLSLYDVWETNNNLYLILEYAEKGELFNLLVDHGPLPEREAINCFRQIII 138
Query: 1153 GLAYLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDM--TMRGTVFWMA 1210
G++Y H+ GI+HRD+K +NLLLD+ KI+DFG++ + +++D+ T G+ + A
Sbjct: 139 GISYCHALGIVHRDLKPENLLLDSFYNIKIADFGMAA----LQTDADLLETSCGSPHYAA 194
Query: 1211 PEMVDTAHGYSAKVDIWSLGCVVLEMFAGKRPW--SNFEVVAAMFQIGKSKTAPPIPDDT 1268
PE+V D+WS G ++ + G+ P+ N V + ++ K + +P+DT
Sbjct: 195 PEIVSGLPYEGFASDVWSCGVILFALLTGRLPFDEENGNVRDLLLKVQKGQF--EMPNDT 252
Query: 1269 KDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPFCK-------TSSSFDFPK--TKLAQF 1319
+ +S Q + + +DP R ++ HP K + S D P+ T L
Sbjct: 253 E--ISRDAQDLIGKILVVDPRQRIKIRDILSHPLLKKYQTIKDSKSIKDLPRENTYLYPL 310
Query: 1320 IKSNDKLNSS 1329
SN+ ++S
Sbjct: 311 ADSNNHTSAS 320
>Hs4758696 [T] KOG4721 Serine/threonine protein kinase contains leucine zipper
domain
Length = 966
Score = 116 bits (290), Expect = 3e-25
Identities = 76/269 (28%), Positives = 133/269 (49%), Gaps = 29/269 (10%)
Query: 1032 EYKEFAWIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSE 1091
E E W+ G G+ GAV+L E +A+K+V E +++
Sbjct: 167 EISELQWL-----GSGAQGAVFLGK--FRAEEVAIKKVR---------------EQNETD 204
Query: 1092 VSTLKDLNHVNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVL 1151
+ L+ L H NI+ + G + Y + +EY A G + ++R + +L+ + +
Sbjct: 205 IKHLRKLKHPNIIAFKGVCTQAPCYCIIMEYCAHGQLYEVLRAGRKITPRLLVDWSTGIA 264
Query: 1152 EGLAYLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAP 1211
G+ YLH I+HRD+K+ N+L+ + KISDFG S++ ++ ++ M+ GTV WMAP
Sbjct: 265 SGMNYLHLHKIIHRDLKSPNVLVTHTDAVKISDFGTSKELSD--KSTKMSFAGTVAWMAP 322
Query: 1212 EMVDTAHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDL 1271
E++ S KVDIWS G V+ E+ G+ P+ + + A ++ +G + P+P D
Sbjct: 323 EVIRN-EPVSEKVDIWSFGVVLWELLTGEIPYKDVDSSAIIWGVGSNSLHLPVPSTCPD- 380
Query: 1272 VSPAGQSFLDQCFEIDPEMRPTADSLVGH 1300
+ + Q ++ P RP+ + H
Sbjct: 381 ---GFKILMKQTWQSKPRNRPSFRQTLMH 406
>Hs7705551 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 632
Score = 115 bits (289), Expect = 4e-25
Identities = 74/283 (26%), Positives = 140/283 (49%), Gaps = 33/283 (11%)
Query: 1044 IGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHVNI 1103
+G G++G+V L ++ +GE++A+K++ +F S +E + EV +LK LNH N+
Sbjct: 10 LGDGTYGSVLLGRSIESGELIAIKKMK-RKFYSWEECMN------QREVKSLKKLNHANV 62
Query: 1104 VQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHSKGIL 1163
V+ +N EY+ + F + IR++ Q+L+GLA++H G
Sbjct: 63 VKLKEVIRENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKLGFF 122
Query: 1164 HRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVDTAHGYSAK 1223
HRD+K +NLL + KI+DFG++R+ + +D T ++ APE++ + YS+
Sbjct: 123 HRDLKPENLLCMGPELVKIADFGLAREIRSKPPYTDYV--STRWYRAPEVLLRSTNYSSP 180
Query: 1224 VDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPP-------------------- 1263
+D+W++GC++ E++ + + + +F+I + P
Sbjct: 181 IDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNFRWPQ 240
Query: 1264 -IPDDTKDLVSPAGQ---SFLDQCFEIDPEMRPTADSLVGHPF 1302
+P++ K L+ A L + DP+ RPTA + +P+
Sbjct: 241 CVPNNLKTLIPNASSEAVQLLRDMLQWDPKKRPTASQALRYPY 283
>Hs7662388 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 632
Score = 115 bits (289), Expect = 4e-25
Identities = 72/283 (25%), Positives = 139/283 (48%), Gaps = 33/283 (11%)
Query: 1044 IGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHVNI 1103
+G G++G+V L ++ +GE++A+K++ +S ++ + EV +LK LNH N+
Sbjct: 10 LGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNLR-------EVKSLKKLNHANV 62
Query: 1104 VQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHSKGIL 1163
V+ +N EY+ + F + IR++ Q+L+GLA++H G
Sbjct: 63 VKLKEVIRENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKHGFF 122
Query: 1164 HRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVDTAHGYSAK 1223
HRD+K +NLL + KI+DFG++R+ + +D T ++ APE++ + YS+
Sbjct: 123 HRDLKPENLLCMGPELVKIADFGLAREIRSKPPYTDYV--STRWYRAPEVLLRSTNYSSP 180
Query: 1224 VDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPP-------------------- 1263
+D+W++GC++ E++ + + + +F+I + P
Sbjct: 181 IDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNFRWPQ 240
Query: 1264 -IPDDTKDLVSPAGQ---SFLDQCFEIDPEMRPTADSLVGHPF 1302
+P++ K L+ A L + DP+ RPTA + +P+
Sbjct: 241 CVPNNLKTLIPNASSEAVQLLRDMLQWDPKKRPTASQALRYPY 283
>Hs18552621 [R] KOG0597 Serine-threonine protein kinase FUSED
Length = 1315
Score = 115 bits (289), Expect = 4e-25
Identities = 78/263 (29%), Positives = 133/263 (49%), Gaps = 19/263 (7%)
Query: 1042 EIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHV 1101
E+IG+GSFG VY + +++A+K +P+ ++ + L+ E+ ++ L H
Sbjct: 8 EMIGEGSFGRVYKGRRKYSAQVVALK--FIPKLGRSEKE----LRNLQREIEIMRGLRHP 61
Query: 1102 NIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHSKG 1161
NIV L E + + +Y A G + ++ G+ + ++ + Q++ L YLHS
Sbjct: 62 NIVHMLDSFETDKEVVVVTDY-AEGELFQILEDDGKLPEDQVQAIAAQLVSALYYLHSHR 120
Query: 1162 ILHRDMKADNLLLDNDGVCKISDFGISR--KSNNIYSNSDMTMRGTVFWMAPEMVDTAHG 1219
ILHRDMK N+LL G K+ DFG +R +N + S ++GT +M+PE+V+
Sbjct: 121 ILHRDMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTS---IKGTPLYMSPELVE-ERP 176
Query: 1220 YSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQSF 1279
Y D+WS+GC++ E+ G P+ ++FQ+ P+ +SP ++F
Sbjct: 177 YDHTADLWSVGCILYELAVGTPPF----YATSIFQLVSLILKDPV--RWPSTISPCFKNF 230
Query: 1280 LDQCFEIDPEMRPTADSLVGHPF 1302
L DP R + L+ HPF
Sbjct: 231 LQGLLTKDPRQRLSWPDLLYHPF 253
>ECU01g0630 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 488
Score = 115 bits (289), Expect = 4e-25
Identities = 82/273 (30%), Positives = 141/273 (51%), Gaps = 20/273 (7%)
Query: 1042 EIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHV 1101
+++G+G++ YLA + +GE A+K V + + S+ + E L+SE++ L++
Sbjct: 44 KLLGRGAYAQCYLA-EIESGEQYAMKVVRLKDIKSR-----KVHEKLESEIAIHSKLDNP 97
Query: 1102 NIVQ-YLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLH-S 1159
N+V+ Y F ++ + LE G++ +L++ G+ ++ + KQ +EGL YLH S
Sbjct: 98 NVVKMYRSFRSSEYVF-MVLELCERGALDALLKRNGKLKERHVARFVKQTVEGLIYLHNS 156
Query: 1160 KGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMV-DTAH 1218
++HRD+K NL LD+ KI DFG+S + +TM GT ++APE++ A
Sbjct: 157 VSVVHRDLKLGNLFLDSKFNVKIGDFGLSAVIKD--GEKKVTMCGTPNYIAPEVLFGKAS 214
Query: 1219 GYSAKVDIWSLGCVVLEMFAGKRPW--SNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAG 1276
G+S + DIWSLG ++ + G P+ N E + M ++ I + DL S A
Sbjct: 215 GHSFEADIWSLGVIIYTLLVGVPPFQKKNVEDIYKMIKLNNY-----IFPENCDLSSEA- 268
Query: 1277 QSFLDQCFEIDPEMRPTADSLVGHPFCKTSSSF 1309
+ Q +P RPT + ++ H F F
Sbjct: 269 IDLITQILNTNPLERPTLEHILSHKFLSKKEHF 301
>At1g03740 [D] KOG0600 Cdc2-related protein kinase
Length = 542
Score = 115 bits (289), Expect = 4e-25
Identities = 93/362 (25%), Positives = 170/362 (46%), Gaps = 39/362 (10%)
Query: 970 KSLKPPKRTKTIRIIAQEASEARKNEVSQKLQRKNTKM-WGTKVVEITDKRTISINKSRN 1028
K ++ P+ ++R++ +E + +RK W + +V + + + R
Sbjct: 151 KGVEKPEVEASVRVVHRELKRGSSIVSPKDAERKQVAAGWPSWLVSVAGESLVDWAPRRA 210
Query: 1029 SRGEYKEFAWIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEAL 1088
+ E K E IG+G++ +VY A ++ +++A+K+V D + + V+ +
Sbjct: 211 NTFE-------KLEKIGQGTYSSVYRARDLLHNKIVALKKVRF------DLNDMESVKFM 257
Query: 1089 KSEVSTLKDLNHVNIVQYLGFEEKNGIYSLFL--EYVAGGSVGSLIRMYGRFDDQLIRHL 1146
E+ ++ L+H N+++ G SL+L EY+ +G +F + ++
Sbjct: 258 AREIIVMRRLDHPNVLKLEGLITAPVSSSLYLVFEYMDHDLLGLSSLPGVKFTEPQVKCY 317
Query: 1147 TKQVLEGLAYLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTV 1206
+Q+L GL + HS+G+LHRD+K NLL+D+ GV KI+DFG++ + S S + T+
Sbjct: 318 MRQLLSGLEHCHSRGVLHRDIKGSNLLIDSKGVLKIADFGLATFFDPAKSVSLTSHVVTL 377
Query: 1207 FWMAPEMVDTAHGYSAKVDIWSLGCVVLEMFAGK--------------------RPWSNF 1246
++ PE++ A Y VD+WS GC++ E++AGK P N+
Sbjct: 378 WYRPPELLLGASHYGVGVDLWSTGCILGELYAGKPILPGKTEVEQLHKIFKLCGSPTENY 437
Query: 1247 EVVAAMFQIGKSKTAPPIPDDTKDLVS--PAG-QSFLDQCFEIDPEMRPTADSLVGHPFC 1303
+ KTA P ++ PA S L+ IDP+ R +AD + +
Sbjct: 438 WRKQKLPSSAGFKTAIPYRRKVSEMFKDFPASVLSLLETLLSIDPDHRSSADRALESEYF 497
Query: 1304 KT 1305
KT
Sbjct: 498 KT 499
>Hs5730055 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 685
Score = 115 bits (288), Expect = 5e-25
Identities = 72/266 (27%), Positives = 137/266 (51%), Gaps = 15/266 (5%)
Query: 1038 WIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKD 1097
+ +G+++GKG F Y ++T ++ A K + + + E + E+ +
Sbjct: 82 YCRGKVLGKGGFAKCYEMTDLTNNKVYAAKIIPHSRVAKPHQR-----EKIDKEIELHRI 136
Query: 1098 LNHVNIVQ-YLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAY 1156
L+H ++VQ Y FE+K IY L LEY + S+ +++ + +R+ +Q++ GL Y
Sbjct: 137 LHHKHVVQFYHYFEDKENIYIL-LEYCSRRSMAHILKARKVLTEPEVRYYLRQIVSGLKY 195
Query: 1157 LHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVDT 1216
LH + ILHRD+K N ++ K+ DFG++ + + + T+ GT +++PE+++
Sbjct: 196 LHEQEILHRDLKLGNFFINEAMELKVGDFGLAARLEPL-EHRRRTICGTPNYLSPEVLN- 253
Query: 1217 AHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAG 1276
G+ + DIW+LGCV+ M G+ P+ + I +++ P L++PA
Sbjct: 254 KQGHGCESDIWALGCVMYTMLLGRPPFETTNLKETYRCIREARYTMP-----SSLLAPA- 307
Query: 1277 QSFLDQCFEIDPEMRPTADSLVGHPF 1302
+ + +PE RP+ D ++ H F
Sbjct: 308 KHLIASMLSKNPEDRPSLDDIIRHDF 333
>At3g61960 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 648
Score = 115 bits (288), Expect = 5e-25
Identities = 78/267 (29%), Positives = 126/267 (46%), Gaps = 13/267 (4%)
Query: 1041 GEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNH 1100
G IG GSF V+LA + ++G +AVK++ S + + + L E+S L ++H
Sbjct: 13 GPRIGSGSFAVVWLAKHRSSGLEVAVKEIDKKLLSPK------VRDNLLKEISILSTIDH 66
Query: 1101 VNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHSK 1160
NI+++ E L LEY +GG + I +G+ + + +H +Q+ GL L K
Sbjct: 67 PNIIRFYEAIETGDRIFLVLEYCSGGDLAGYINRHGKVPEAVAKHFMRQLALGLQVLQEK 126
Query: 1161 GILHRDMKADNLLLDNDGV---CKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVDTA 1217
+HRD+K NLLL + V KI DFG +R + T G+ +MAPE++
Sbjct: 127 HFIHRDLKPQNLLLSSKEVTPLLKIGDFGFARSLTP--ESMAETFCGSPLYMAPEIIRN- 183
Query: 1218 HGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQ 1277
Y AK D+WS G ++ ++ GK P+ + I + T P+DT++ + P
Sbjct: 184 QKYDAKADLWSAGAILFQLVTGKPPFDGNNHIQLFHNIVRD-TELKFPEDTRNEIHPDCV 242
Query: 1278 SFLDQCFEIDPEMRPTADSLVGHPFCK 1304
+P R T H F +
Sbjct: 243 DLCRSLLRRNPIERLTFREFFNHMFLR 269
>At1g71530 [D] KOG0600 Cdc2-related protein kinase
Length = 655
Score = 115 bits (288), Expect = 5e-25
Identities = 82/290 (28%), Positives = 143/290 (49%), Gaps = 37/290 (12%)
Query: 1044 IGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHVNI 1103
IG+G++ +VY A ++ TG+++A+K+V F + D ++ + E+ L+ L+H N+
Sbjct: 153 IGQGTYSSVYKARDLETGKIVAMKKV---RFVNMDPESVRF---MAREILILRKLDHPNV 206
Query: 1104 VQYLGFEEKNGIYSLFL--EYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHSKG 1161
++ G SL+L EY+ G +F + I+ +Q+ GL + H +G
Sbjct: 207 MKLEGLVTSRLSGSLYLVFEYMEHDLAGLAATPGIKFSEPQIKCYMQQLFRGLEHCHRRG 266
Query: 1162 ILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRG---TVFWMAPEMVDTAH 1218
ILHRD+K NLL++N+GV KI DFG+ +N + D+ + T+++ APE++ A
Sbjct: 267 ILHRDIKGSNLLINNEGVLKIGDFGL---ANFYRGDGDLQLTSRVVTLWYRAPELLLGAT 323
Query: 1219 GYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAP---------------- 1262
Y +D+WS GC++ E+FAGK V M +I K +P
Sbjct: 324 EYGPAIDLWSAGCILTELFAGKPIMPGRTEVEQMHKIFKLCGSPSEDYWRRATLPLATSF 383
Query: 1263 -------PIPDDTKDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPFCKT 1305
P+ +T + + +++ I+PE R +A S + F T
Sbjct: 384 KPSHPYKPVLAETFNHFPSSALMLINKLLAIEPEKRGSAASTLRSEFFTT 433
>SPAC19E9.02 [D] KOG0591 NIMA (never in mitosis)-related G2-specific
serine/threonine protein kinase
Length = 722
Score = 115 bits (287), Expect = 6e-25
Identities = 86/290 (29%), Positives = 141/290 (47%), Gaps = 48/290 (16%)
Query: 1042 EIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHV 1101
E IG GSFG +Y + G +LA K++ + Q++ I+ EV+ L++L H
Sbjct: 8 ECIGHGSFGRIYKVQRLKDGALLAQKEIHFGNITRQEKQYIA------DEVNILRNLKHP 61
Query: 1102 NIVQYLGFEEKNG--IYSLFLEYVAGGSVGSLIRMYG----RFDDQLIRHLTKQVLEGLA 1155
NIVQY G E + +L++EY G + +LI+ Y RF +Q + Q+L L
Sbjct: 62 NIVQYCGEELNRSAQVINLYMEYCGHGDLANLIQRYKEEKKRFTEQEVLKFFTQLLLALY 121
Query: 1156 YLH-------------------SKGILHRDMKADNLLLDNDGVCKISDFGISRKSNN--I 1194
H + +LHRD+K N+ LD + K+ DFG+S+ +N +
Sbjct: 122 RCHYGENAPACDSQWPREIFHPKQSVLHRDIKPANIFLDENNSVKLGDFGLSKLLDNTRV 181
Query: 1195 YSNSDMTMRGTVFWMAPEMVDTAHGYSAKVDIWSLGCVVLEMFAGKRPW---SNFEVVAA 1251
++ S + GT ++M+PE++ ++ YSAK D+W+LGCV+ E+ P+ S E+
Sbjct: 182 FTQSYV---GTPYYMSPEIIRSS-PYSAKSDVWALGCVIFEICMLTHPFEGRSYLELQRN 237
Query: 1252 MFQIGKSKTAPPIPDDTKDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHP 1301
+ Q S DD L+ C E++ ++RPT L+ P
Sbjct: 238 ICQGNLSCWDHHYSDDVFLLIR--------HCLEVNSDLRPTTYQLLRSP 279
>CE12408 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 527
Score = 115 bits (287), Expect = 6e-25
Identities = 74/302 (24%), Positives = 146/302 (47%), Gaps = 35/302 (11%)
Query: 1036 FAWIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTL 1095
F ++ + +G G+FG V LA + TG+ +A+K++ +S ++ ++ EV +L
Sbjct: 43 FRYLMTKRLGDGTFGEVMLAKKIDTGDRVAIKRMKKKFYSWEEAMSLR-------EVKSL 95
Query: 1096 KDLNHVNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLA 1155
K LNH NI++ +N I E++ + F + +IR++ QVL+GLA
Sbjct: 96 KKLNHPNIIKLREVIRENDILYFVFEFMQENLYELMKDRDRYFPESVIRNIIYQVLQGLA 155
Query: 1156 YLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVD 1215
++H G HRDMK +N++ + + KI+DFG++R+ + +D T ++ APE++
Sbjct: 156 FMHKNGFFHRDMKPENIMCNGTELVKIADFGLAREIRSKPPYTDYV--STRWYRAPEILL 213
Query: 1216 TAHGYSAKVDIWSLGCVVLEMF------------------------AGKRPW-SNFEVVA 1250
+ Y++ +D+W+LGC++ E++ K W +++ +
Sbjct: 214 RSTSYNSPIDMWALGCIMAELYILRPLFPGTSEMDQLFKIISILGTPNKDEWPEGYQLAS 273
Query: 1251 AMFQIGKSKTAPPIPDDTKDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPFCKTSSSFD 1310
AM + A P+ + + +S G + +PE RP A+ + + + + +
Sbjct: 274 AMNFRFQQVVATPM-EQVVNTISKEGMKLMMDMMLWNPEKRPNANQSLRYKYFQVAEKLG 332
Query: 1311 FP 1312
P
Sbjct: 333 AP 334
>CE05425 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 542
Score = 115 bits (287), Expect = 6e-25
Identities = 92/358 (25%), Positives = 166/358 (45%), Gaps = 26/358 (7%)
Query: 945 LKTKSEQQPAFLSSRGESSQFLTPVKSLKPPKRTKTIRIIAQEASEARKNEVSQKLQRKN 1004
L ++++ P + E + ++ P RT T ++ + S + + + Q K
Sbjct: 170 LPLRNQKPPMSTTFGVEKPHQYQQIITIVAPSRTTTPQLQPKSPSTPQ----AMRQQPKC 225
Query: 1005 TKMWGTKVVEITDKRTISINKSRNSRGEYKEFAWIKGEIIGKGSFGAVYLALNVTTGEML 1064
T+ + K + R+ +YK+ IG+GS G V A ++T +++
Sbjct: 226 TEGVSDEEFRNALKFVVDGTDPRSDLTDYKQ--------IGEGSTGVVEAAYKISTKQIV 277
Query: 1065 AVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHVNIVQYLGFEEKNGIYSLFLEYVA 1124
AVK++ + + + E L +EVS L+ H NIV++ + + +E++
Sbjct: 278 AVKRMNLRKQQRR--------ELLFNEVSILRQYQHPNIVRFFSSHLVDDELWVVMEFME 329
Query: 1125 GGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHSKGILHRDMKADNLLLDNDGVCKISD 1184
GGS+ ++ R + I +++QVL L +LH++ ++HRD+K+D++LL DG K++D
Sbjct: 330 GGSLTDIVTAT-RMTEPQIATISRQVLGALDFLHARKVIHRDIKSDSILLKRDGTVKLTD 388
Query: 1185 FGISRKSNNIYSNSDMTMRGTVFWMAPEMVDTAHGYSAKVDIWSLGCVVLEMFAGKRPWS 1244
FG + + ++ GT +W A E++ Y + DIWS G +++EM G+ P+
Sbjct: 389 FGFCGQLSEEVPRR-RSLVGTPYWTAAEVI-AREPYDTRADIWSFGIMLIEMVEGEPPFF 446
Query: 1245 NFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPF 1302
N + AM +I A VS L C D R A L+ HPF
Sbjct: 447 NDQPFQAMKRIRDEHEA---RFSRHAKVSVELSELLSHCIVKDVNKRWPAKDLLRHPF 501
>At5g01820 [T] KOG0583 Serine/threonine protein kinase
Length = 442
Score = 115 bits (287), Expect = 6e-25
Identities = 76/265 (28%), Positives = 135/265 (50%), Gaps = 13/265 (4%)
Query: 1041 GEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNH 1100
G+++G G+F VY + TG+ +A+K V S Q + ++ E++ + L H
Sbjct: 25 GKLVGCGAFAKVYHGRSTATGQSVAIKVV-----SKQRLQKGGLNGNIQREIAIMHRLRH 79
Query: 1101 VNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHSK 1160
+IV+ +E+ GG + + + GRF + L R +Q++ + Y HS+
Sbjct: 80 PSIVRLFEVLATKSKIFFVMEFAKGGELFAKVSK-GRFCEDLSRRYFQQLISAVGYCHSR 138
Query: 1161 GILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDM-TMRGTVFWMAPEMVDTAHG 1219
GI HRD+K +NLLLD KISDFG+S ++ I + + T+ GT ++APE++
Sbjct: 139 GIFHRDLKPENLLLDEKLDLKISDFGLSALTDQIRPDGLLHTLCGTPAYVAPEVLAKKGY 198
Query: 1220 YSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQSF 1279
AK+DIWS G ++ + AG P+++ ++ +I K + P SP +
Sbjct: 199 DGAKIDIWSCGIILFVLNAGYLPFNDHNLMVMYRKIYKGEFRIP------KWTSPDLRRL 252
Query: 1280 LDQCFEIDPEMRPTADSLVGHPFCK 1304
L + + +P+ R T + ++ P+ K
Sbjct: 253 LTRLLDTNPQTRITIEEIIHDPWFK 277
>7298652 [D] KOG0615 Serine/threonine protein kinase Chk2 and related proteins
Length = 459
Score = 115 bits (287), Expect = 6e-25
Identities = 109/395 (27%), Positives = 181/395 (45%), Gaps = 44/395 (11%)
Query: 939 RGFEKSLKTKSEQ--QPAFLSSRGESSQFLTPVKSLKPPK---RTKTIRIIAQEASEARK 993
R + K++K KS F + RGE++ + + L P K R + I + A+
Sbjct: 34 RLYGKNIKIKSLDLNNDEFTAGRGEANDLILTLNDL-PEKILTRISKVHFIIKRANCELT 92
Query: 994 NEVS-QKLQRK----NTKMWGTKVVEITDK----------------RTISINKSRNSRGE 1032
N V Q L R N + GT + I + +S N+S E
Sbjct: 93 NPVYIQDLSRNGTFVNNEKIGTNRMRILKNDDVISLSHPTYKAFVFKDLSPNESIGLPEE 152
Query: 1033 YKEFAWIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESA-ISMVEALKSE 1091
+ ++ ++ G G++G V L + T + A+K V S S S + + +E
Sbjct: 153 INKTYYVNRKL-GSGAYGLVRLVYDTRTCQQFAMKIVKKNMLSGARPSTNFSDPDRVLNE 211
Query: 1092 VSTLKDLNHVNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVL 1151
+K+L+H +V+ +K + LE++ GG + + I + + + Q+
Sbjct: 212 AKIMKNLSHPCVVRMHDIVDKPDSVYMVLEFMRGGDLLNRIISNKLLSEDISKLYFYQMC 271
Query: 1152 EGLAYLHSKGILHRDMKADNLLL---DNDGVCKISDFGISRKSNNIYSNSDMTMR---GT 1205
+ YLH +GI HRD+K DN+LL D + + K+SDFG+S+ + D MR GT
Sbjct: 272 HAVKYLHDRGITHRDLKPDNVLLETNDEETLLKVSDFGLSK-----FVQKDSVMRTLCGT 326
Query: 1206 VFWMAPEMVDTA--HGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPP 1263
++APE++ T Y+ KVDIWSLG V+ +G P+S+ A QI K + A
Sbjct: 327 PLYVAPEVLITGGREAYTKKVDIWSLGVVLFTCLSGTLPFSDEYGTPAAQQIKKGRFAYG 386
Query: 1264 IPDDTKDLVSPAGQSFLDQCFEIDPEMRPTADSLV 1298
P + VS + ++Q +DPE RP+ D ++
Sbjct: 387 HP--SWKSVSQRAKLLINQMLIVDPERRPSIDDVL 419
>Hs4758016 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 607
Score = 114 bits (286), Expect = 8e-25
Identities = 77/266 (28%), Positives = 129/266 (47%), Gaps = 15/266 (5%)
Query: 1038 WIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKD 1097
++KG ++GKG F Y A + TG AVK + + + E + +E+ +D
Sbjct: 23 YLKGRLLGKGGFARCYEATDTETGSAYAVKVIPQSRVAKPHQR-----EKILNEIELHRD 77
Query: 1098 LNHVNIVQYLG-FEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAY 1156
L H +IV++ FE+ + IY +FLE + S+ + + + +R+ +Q+L GL Y
Sbjct: 78 LQHRHIVRFSHHFEDADNIY-IFLELCSRKSLAHIWKARHTLLEPEVRYYLRQILSGLKY 136
Query: 1157 LHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVDT 1216
LH +GILHRD+K N + + K+ DFG++ + T+ GT ++APE++
Sbjct: 137 LHQRGILHRDLKLGNFFITENMELKVGDFGLAARLEP-PEQRKKTICGTPNYVAPEVL-L 194
Query: 1217 AHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAG 1276
G+ + D+WSLGCV+ + G P+ ++ I + P L PA
Sbjct: 195 RQGHGPEADVWSLGCVMYTLLCGSPPFETADLKETYRCIKQVHYTLP-----ASLSLPAR 249
Query: 1277 QSFLDQCFEIDPEMRPTADSLVGHPF 1302
Q L P RP+ D ++ H F
Sbjct: 250 Q-LLAAILRASPRDRPSIDQILRHDF 274
>Hs22068916 [T] KOG0696 Serine/threonine protein kinase
Length = 673
Score = 114 bits (286), Expect = 8e-25
Identities = 88/267 (32%), Positives = 139/267 (51%), Gaps = 22/267 (8%)
Query: 984 IAQEASEARKNEVSQKLQRKNTKMWGTKVVEITDKRTISI--NKSRNSRGEYKEFAWIKG 1041
+ E SEA + E+ QK +R GTKV E T+S N R + +F ++
Sbjct: 290 VPPEGSEANE-ELRQKFERAKISQ-GTKVPEEKTTNTVSKFDNNGNRDRMKLTDFNFLM- 346
Query: 1042 EIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVE----ALKSEVSTLKD 1097
++GKGSFG V L+ T E+ AVK + D+ +MVE AL + L
Sbjct: 347 -VLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGKPPFLTQ 405
Query: 1098 LNHVNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYL 1157
L+ F+ + +Y + +EYV GG + I+ GRF + ++ GL +L
Sbjct: 406 LHSC-------FQTMDRLYFV-MEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFL 457
Query: 1158 HSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSN-SDMTMRGTVFWMAPEMVDT 1216
SKGI++RD+K DN++LD++G KI+DFG+ ++ NI+ + T GT ++APE++
Sbjct: 458 QSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKE--NIWDGVTTKTFCGTPDYIAPEII-A 514
Query: 1217 AHGYSAKVDIWSLGCVVLEMFAGKRPW 1243
Y VD W+ G ++ EM AG+ P+
Sbjct: 515 YQPYGKSVDWWAFGVLLYEMLAGQAPF 541
>Hs20149547 [T] KOG0603 Ribosomal protein S6 kinase
Length = 735
Score = 114 bits (286), Expect = 8e-25
Identities = 80/271 (29%), Positives = 141/271 (51%), Gaps = 21/271 (7%)
Query: 1025 KSRNSRGEYKEFAWIKGEIIGKGSFGAVYLALNVT---TGEMLAVKQVTVPEFSSQDESA 1081
K+ + + + F +K ++G+GSFG V+L VT +G + A+K + +D
Sbjct: 51 KAGSEKADPSHFELLK--VLGQGSFGKVFLVRKVTRPDSGHLYAMKVLKKATLKVRDRVR 108
Query: 1082 ISMVEALKSEVSTLKDLNHVNIVQ-YLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDD 1140
M E L D+NH +V+ + F+ + +Y L L+++ GG + + + F +
Sbjct: 109 TKM------ERDILADVNHPFVVKLHYAFQTEGKLY-LILDFLRGGDLFTRLSKEVMFTE 161
Query: 1141 QLIRHLTKQVLEGLAYLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDM 1200
+ ++ ++ GL +LHS GI++RD+K +N+LLD +G K++DFG+S+++ + +
Sbjct: 162 EDVKFYLAELALGLDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKEAID-HEKKAY 220
Query: 1201 TMRGTVFWMAPEMVDTAHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKT 1260
+ GTV +MAPE+V+ G+S D WS G ++ EM G P+ + M I K+K
Sbjct: 221 SFCGTVEYMAPEVVN-RQGHSHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKL 279
Query: 1261 APPIPDDTKDLVSPAGQSFLDQCFEIDPEMR 1291
P +S QS L F+ +P R
Sbjct: 280 GMP------QFLSTEAQSLLRALFKRNPANR 304
Score = 82.0 bits (201), Expect = 6e-15
Identities = 71/272 (26%), Positives = 122/272 (44%), Gaps = 22/272 (8%)
Query: 1038 WIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKD 1097
++ E IG GS+ ++ T AVK + + +E I + + TLKD
Sbjct: 418 YVVKETIGVGSYSECKRCVHKATNMEYAVKVIDKSKRDPSEEIEILLRYGQHPNIITLKD 477
Query: 1098 LNHVNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYL 1157
+ +++ +Y L E + GG + I F ++ + + + + YL
Sbjct: 478 V----------YDDGKHVY-LVTELMRGGELLDKILRQKFFSEREASFVLHTIGKTVEYL 526
Query: 1158 HSKGILHRDMKADNLL-LDNDG---VCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEM 1213
HS+G++HRD+K N+L +D G +I DFG + K + MT T ++APE+
Sbjct: 527 HSQGVVHRDLKPSNILYVDESGNPECLRICDFGFA-KQLRAENGLLMTPCYTANFVAPEV 585
Query: 1214 VDTAHGYSAKVDIWSLGCVVLEMFAGKRPWSN---FEVVAAMFQIGKSKTAPPIPDDTKD 1270
+ GY DIWSLG ++ M AG P++N + +IG K + +
Sbjct: 586 L-KRQGYDEGCDIWSLGILLYTMLAGYTPFANGPSDTPEEILTRIGSGKFT--LSGGNWN 642
Query: 1271 LVSPAGQSFLDQCFEIDPEMRPTADSLVGHPF 1302
VS + + + +DP R TA ++ HP+
Sbjct: 643 TVSETAKDLVSKMLHVDPHQRLTAKQVLQHPW 674
>Hs20127450 [T] KOG0696 Serine/threonine protein kinase
Length = 673
Score = 114 bits (286), Expect = 8e-25
Identities = 88/267 (32%), Positives = 139/267 (51%), Gaps = 22/267 (8%)
Query: 984 IAQEASEARKNEVSQKLQRKNTKMWGTKVVEITDKRTISI--NKSRNSRGEYKEFAWIKG 1041
+ E SEA + E+ QK +R GTKV E T+S N R + +F ++
Sbjct: 290 VPPEGSEANE-ELRQKFERAKISQ-GTKVPEEKTTNTVSKFDNNGNRDRMKLTDFNFLM- 346
Query: 1042 EIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVE----ALKSEVSTLKD 1097
++GKGSFG V L+ T E+ AVK + D+ +MVE AL + L
Sbjct: 347 -VLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGKPPFLTQ 405
Query: 1098 LNHVNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYL 1157
L+ F+ + +Y + +EYV GG + I+ GRF + ++ GL +L
Sbjct: 406 LHSC-------FQTMDRLYFV-MEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFL 457
Query: 1158 HSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSN-SDMTMRGTVFWMAPEMVDT 1216
SKGI++RD+K DN++LD++G KI+DFG+ ++ NI+ + T GT ++APE++
Sbjct: 458 QSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKE--NIWDGVTTKTFCGTPDYIAPEII-A 514
Query: 1217 AHGYSAKVDIWSLGCVVLEMFAGKRPW 1243
Y VD W+ G ++ EM AG+ P+
Sbjct: 515 YQPYGKSVDWWAFGVLLYEMLAGQAPF 541
>At1g67890 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 738
Score = 114 bits (286), Expect = 8e-25
Identities = 77/247 (31%), Positives = 125/247 (50%), Gaps = 18/247 (7%)
Query: 1041 GEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNH 1100
GE IG+GS G VY L G +AVK + E+S + ++ + K EVS +K L H
Sbjct: 490 GEQIGQGSCGTVYHGL--WFGSDVAVKVFSKQEYSEE------IITSFKQEVSLMKRLRH 541
Query: 1101 VNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLI-RMYGRFDDQLIRHLTKQVLEGLAYLH- 1158
N++ ++G + E++ GS+ L+ R + D + H+ + G+ YLH
Sbjct: 542 PNVLLFMGAVASPQRLCIVTEFLPRGSLFRLLQRNKSKLDLRRRIHMASDIARGMNYLHH 601
Query: 1159 -SKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVDTA 1217
S I+HRD+K+ NLL+D + K++DFG+SR + Y ++ RGT WMAPE++
Sbjct: 602 CSPPIIHRDLKSSNLLVDRNWTVKVADFGLSRIKHETYLTTN--GRGTPQWMAPEVLRN- 658
Query: 1218 HGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQ 1277
K D++S G V+ E+ K PW N + + +G +P D V P
Sbjct: 659 EAADEKSDVYSFGVVLWELVTEKIPWENLNAMQVIGAVGFMNQRLEVPKD----VDPQWI 714
Query: 1278 SFLDQCF 1284
+ ++ C+
Sbjct: 715 ALMESCW 721
>At1g53050 [D] KOG0600 Cdc2-related protein kinase
Length = 694
Score = 114 bits (286), Expect = 8e-25
Identities = 78/276 (28%), Positives = 137/276 (49%), Gaps = 33/276 (11%)
Query: 992 RKNEVSQKLQRKNTKMWGTKV--VEITDKRTISINKSRNSRGEYKEFAW----------- 1038
+++ VS L+ +N ++ V T +SI ++ + GEY W
Sbjct: 63 KQSNVSLHLRGENLSRREKRIENVAATSPLAMSITIAKATEGEYVAAGWPPWLASVAGEA 122
Query: 1039 IKGEI------------IGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVE 1086
I+G + IG+G++ VY A ++ +++A+K+V + V
Sbjct: 123 IRGWVPRRADSFEKLDKIGQGTYSNVYRARDLDQKKIVALKKVRFDNLEPES------VR 176
Query: 1087 ALKSEVSTLKDLNHVNIVQYLGFEEKNGIYSLFL--EYVAGGSVGSLIRMYGRFDDQLIR 1144
+ E+ L+ L+H NI++ G SL+L EY+ G +F + ++
Sbjct: 177 FMAREIQILRRLDHPNIIKLEGLVTSRMSCSLYLVFEYMEHDLAGLASHPAIKFSESQVK 236
Query: 1145 HLTKQVLEGLAYLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRG 1204
+Q+L GL + HS+G+LHRD+K NLL+DN GV KI+DFG++ + + +
Sbjct: 237 CYLQQLLHGLDHCHSRGVLHRDIKGSNLLIDNSGVLKIADFGLASFFDPRQTQPLTSRVV 296
Query: 1205 TVFWMAPEMVDTAHGYSAKVDIWSLGCVVLEMFAGK 1240
T+++ PE++ A Y A VD+WS GC++ E++AGK
Sbjct: 297 TLWYRPPELLLGATRYGAAVDLWSAGCILAELYAGK 332
>Hs7657214 [T] KOG0583 Serine/threonine protein kinase
Length = 714
Score = 114 bits (285), Expect = 1e-24
Identities = 77/251 (30%), Positives = 124/251 (48%), Gaps = 11/251 (4%)
Query: 1044 IGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHVNI 1103
+G+GSF V L+V TGE +A+K + + + + + L+ E + + H NI
Sbjct: 68 LGEGSFAKVREGLHVLTGEKVAIKVID----KKRAKKDTYVTKNLRREGQIQQMIRHPNI 123
Query: 1104 VQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHSKGIL 1163
Q L E Y L +E GG++ I R ++ R +Q++ + +LH G++
Sbjct: 124 TQLLDILETENSYYLVMELCPGGNLMHKIYEKKRLEESEARRYIRQLISAVEHLHRAGVV 183
Query: 1164 HRDMKADNLLLDNDGVCKISDFGISRKSNNI-YSNSDMTMRGTVFWMAPEMVDTAHGYSA 1222
HRD+K +NLLLD D K+ DFG+S + + YS+ T G+ + APE++ Y
Sbjct: 184 HRDLKIENLLLDEDNNIKLIDFGLSNCAGILGYSDPFSTQCGSPAYAAPELL-ARKKYGP 242
Query: 1223 KVDIWSLGCVVLEMFAGKRPWSNFEV-VAAMFQIGKSKTAPPIPDDTKDLVSPAGQSFLD 1281
K+D+WS+G + M G P++ + A++Q K P+P +S SFL
Sbjct: 243 KIDVWSIGVNMYAMLTGTLPFTVEPFSLRALYQKMVDKEMNPLPTQ----LSTGAISFLR 298
Query: 1282 QCFEIDPEMRP 1292
E DP RP
Sbjct: 299 SLLEPDPVKRP 309
>Hs4506539 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 671
Score = 114 bits (285), Expect = 1e-24
Identities = 80/273 (29%), Positives = 133/273 (48%), Gaps = 21/273 (7%)
Query: 1034 KEFAWIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVS 1093
K +++ + G FG V L + T G M+ P + I EAL E
Sbjct: 13 KSSDFLESAELDSGGFGKVSLCFHRTQGLMIMKTVYKGP-------NCIEHNEALLEEAK 65
Query: 1094 TLKDLNHVNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEG 1153
+ L H +V+ LG + G YSL +EY+ G++ +++ + + +++EG
Sbjct: 66 MMNRLRHSRVVKLLGVIIEEGKYSLVMEYMEKGNLMHVLKAEMSTPLSVKGRIILEIIEG 125
Query: 1154 LAYLHSKGILHRDMKADNLLLDNDGVCKISDFGIS-----RKSNNIYSNS----DMTMR- 1203
+ YLH KG++H+D+K +N+L+DND KI+D G++ K NN N D T +
Sbjct: 126 MCYLHGKGVIHKDLKPENILVDNDFHIKIADLGLASFKMWSKLNNEEHNELREVDGTAKK 185
Query: 1204 --GTVFWMAPEMVDTAHGY-SAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKT 1260
GT+++MAPE ++ + + K D++S V+ +FA K P+ N + KS
Sbjct: 186 NGGTLYYMAPEHLNDVNAKPTEKSDVYSFAVVLWAIFANKEPYENAICEQQLIMCIKSGN 245
Query: 1261 APPIPDDTKDLVSPAGQSFLDQCFEIDPEMRPT 1293
P + DD + S + C+E +PE RPT
Sbjct: 246 RPDV-DDITEYCPREIISLMKLCWEANPEARPT 277
>Hs20479818 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand protein
superfamily
Length = 514
Score = 114 bits (285), Expect = 1e-24
Identities = 85/307 (27%), Positives = 153/307 (49%), Gaps = 24/307 (7%)
Query: 1027 RNSRGEYKEFAWIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVE 1086
R G E + G I+GKGSFG V A + T A+K+V +++++ S V+
Sbjct: 105 RIENGAAIEEIYTFGRILGKGSFGIVIEATDKETETKWAIKKV------NKEKAGSSAVK 158
Query: 1087 ALKSEVSTLKDLNHVNIVQYLG-FEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRH 1145
L+ EV+ LK + H +I+ FE +Y L +E G + ++ G F + R
Sbjct: 159 LLEREVNILKSVKHEHIIHLEQVFETPKKMY-LVMELCEDGELKEILDRKGHFSENETRW 217
Query: 1146 LTKQVLEGLAYLHSKGILHRDMKADNLLL------DNDGV---CKISDFGISRKSNNIYS 1196
+ + + +AYLH+ I+HRD+K +N+++ DN+ + K++DFG++ K +
Sbjct: 218 IIQSLASAIAYLHNNDIVHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSE 277
Query: 1197 NSDMTMRGTVFWMAPEMVDTAHGYSAKVDIWSLGCVVLEMFAGKRPW--SNFEVVAAMFQ 1254
GT +MAPE++ +AH YS + DIWS+G V+ + G+ P+ S+ E + + +
Sbjct: 278 AMLQATCGTPIYMAPEVI-SAHDYSQQCDIWSIGVVMYMLLRGEPPFLASSEEKLFELIR 336
Query: 1255 IGKSKTAPPIPDDTKDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPFCKTSSSFDFPKT 1314
G+ + + +S +S L Q ++DP R TA L+ + + + T
Sbjct: 337 KGELH----FENAVWNSISDCAKSVLKQLMKVDPAHRITAKELLDNQWLTGNKLSSVRPT 392
Query: 1315 KLAQFIK 1321
+ + +K
Sbjct: 393 NVLEMMK 399
>At3g05050 [D] KOG0600 Cdc2-related protein kinase
Length = 593
Score = 114 bits (285), Expect = 1e-24
Identities = 85/308 (27%), Positives = 141/308 (45%), Gaps = 43/308 (13%)
Query: 1044 IGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHVNI 1103
IG G++ VY A + TG ++A+K+V D + ++ + E+ L+ L+H N+
Sbjct: 144 IGSGTYSNVYKAKDSLTGNIVALKKVRC------DVNERESLKFMAREILILRRLDHPNV 197
Query: 1104 VQYLGFEEKNGIYSLFL--EYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHSKG 1161
++ G SL+L Y+ G +F +Q ++ KQ+L GL + H++G
Sbjct: 198 IKLEGLVTSRMSSSLYLVFRYMDHDLAGLAASPEIKFTEQQVKCYMKQLLSGLEHCHNRG 257
Query: 1162 ILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFW-MAPEMVDTAHGY 1220
+LHRD+K NLL+D+ GV +I DFG++ + +MT R W +PE++ Y
Sbjct: 258 VLHRDIKGSNLLIDDGGVLRIGDFGLA-TFFDASKRQEMTNRVVTLWYRSPELLHGVVEY 316
Query: 1221 SAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAP------------------ 1262
S VD+WS GC++ E+ AG+ V + +I K +P
Sbjct: 317 SVGVDLWSAGCILAELLAGRAIMPGRNEVEQLHRIYKLCGSPSEEYWKKIRLPSTHKHAH 376
Query: 1263 --PIPDDTKDL------VSPAGQSFLDQCFEIDPEMRPTADSLVGHPF-------CKTSS 1307
P+P + + SP S LD +DP R TA ++ F C+ S
Sbjct: 377 HKPLPQYKRRIREVYKDFSPEALSLLDTLLALDPAERQTATDVLMSDFFTTEPLACQPSD 436
Query: 1308 SFDFPKTK 1315
+P +K
Sbjct: 437 LPKYPPSK 444
>At1g48260 [T] KOG0583 Serine/threonine protein kinase
Length = 432
Score = 114 bits (285), Expect = 1e-24
Identities = 83/278 (29%), Positives = 142/278 (50%), Gaps = 23/278 (8%)
Query: 1041 GEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEA---LKSEVSTLKD 1097
G +G+G+ V A++ TGE A+K + ++S I+ + +K E+ TLK
Sbjct: 14 GRTLGEGNSAKVKFAIDTLTGESFAIKII--------EKSCITRLNVSFQIKREIRTLKV 65
Query: 1098 LNHVNIVQ-YLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAY 1156
L H NIV+ + K IY + LE V GG + I G+ + R + +Q+++G++Y
Sbjct: 66 LKHPNIVRLHEVLASKTKIY-MVLECVTGGDLFDRIVSKGKLSETQGRKMFQQLIDGVSY 124
Query: 1157 LHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDM-TMRGTVFWMAPEMVD 1215
H+KG+ HRD+K +N+LLD G KI+DFG+S S + + + T G+ ++APE++
Sbjct: 125 CHNKGVFHRDLKLENVLLDAKGHIKITDFGLSALSQHYREDGLLHTTCGSPNYVAPEVLA 184
Query: 1216 TAHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPA 1275
A DIWS G ++ + G P+ + + +I K PPIP +S
Sbjct: 185 NEGYDGAASDIWSCGVILYVILTGCLPFDDANLAVICRKIFKGD--PPIP----RWISLG 238
Query: 1276 GQSFLDQCFEIDPEMRPTADSLVGHPFCK---TSSSFD 1310
++ + + + +P R T + H + K T S++D
Sbjct: 239 AKTMIKRMLDPNPVTRVTIAGIKAHDWFKHDYTPSNYD 276
>HsM4885147 [T] KOG0201 Serine/threonine protein kinase
Length = 467
Score = 114 bits (284), Expect = 1e-24
Identities = 83/265 (31%), Positives = 129/265 (48%), Gaps = 21/265 (7%)
Query: 1039 IKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDL 1098
I + I +G+FG VYLA ++ T + +A K + V +F D V
Sbjct: 139 IGSDFIPRGAFGKVYLAQDIKTKKRMACKLIPVDQFKPSD-------------VEIQACF 185
Query: 1099 NHVNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLH 1158
H NI + G LF+E GGSV + G + I +TK VL+GL +LH
Sbjct: 186 RHENIAELYGAVLWGETVHLFMEAGEGGSVLEKLESCGPMREFEIIWVTKHVLKGLDFLH 245
Query: 1159 SKGILHRDMKADNLLLDNDGVCKISDFGIS-RKSNNIYSNSDMTMRGTVFWMAPEMVDTA 1217
SK ++H D+K N++ + + DFG+S + + ++Y D +RGT +M+PE++
Sbjct: 246 SKKVIHHDIKPSNIVFMSTKAVLV-DFGLSVQMTEDVYFPKD--LRGTEIYMSPEVI-LC 301
Query: 1218 HGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAA--MFQIGKSKTAPPIPDDTKDLVSPA 1275
G+S K DI+SLG ++ M G PW +A + K APP+ +D D SP
Sbjct: 302 RGHSTKADIYSLGATLIHMQTGTPPWVKRYPRSAYPSYLYIIHKQAPPL-EDIADDCSPG 360
Query: 1276 GQSFLDQCFEIDPEMRPTADSLVGH 1300
+ ++ E +P RP A L+ H
Sbjct: 361 MRELIEASLERNPNHRPRAADLLKH 385
>Hs4557439 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 305
Score = 114 bits (284), Expect = 1e-24
Identities = 83/297 (27%), Positives = 144/297 (47%), Gaps = 51/297 (17%)
Query: 1040 KGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVP-EFSSQDESAISMVEALKSEVSTLKDL 1098
K E IG+G++G VY A N TG+++A+K++ + E +AI E+S LK+L
Sbjct: 6 KVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIR-------EISLLKEL 58
Query: 1099 NHVNIVQYLGFEEKNGIYSLFLEYVA-------GGSVGSLIRMYGRFDDQLIRHLTKQVL 1151
H NIV+ L L E+++ + GS + ++ LI+ Q+L
Sbjct: 59 KHPNIVRLLDVVHNERKLYLVFEFLSQDLKKYMDSTPGSELPLH------LIKSYLFQLL 112
Query: 1152 EGLAYLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSN---NIYSNSDMTMRGTVFW 1208
+G+++ HS ++HRD+K NLL++ G K++DFG++R Y++ +T+ ++
Sbjct: 113 QGVSFCHSHRVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTL----WY 168
Query: 1209 MAPEMVDTAHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAP------ 1262
APE++ + Y+ VDIWS+GC+ EM K + + +F+I + P
Sbjct: 169 RAPEILLGSKFYTTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDTWP 228
Query: 1263 ---PIPD--------------DTKDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPF 1302
+PD + + P G+ L Q + DP R TA + + HP+
Sbjct: 229 GVTQLPDYKGSFPKWTRKGLEEIVPNLEPEGRDLLMQLLQYDPSQRITAKTALAHPY 285
>Hs22035598 [T] KOG0201 Serine/threonine protein kinase
Length = 467
Score = 114 bits (284), Expect = 1e-24
Identities = 83/265 (31%), Positives = 129/265 (48%), Gaps = 21/265 (7%)
Query: 1039 IKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDL 1098
I + I +G+FG VYLA ++ T + +A K + V +F D V
Sbjct: 139 IGSDFIPRGAFGKVYLAQDIKTKKRMACKLIPVDQFKPSD-------------VEIQACF 185
Query: 1099 NHVNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLH 1158
H NI + G LF+E GGSV + G + I +TK VL+GL +LH
Sbjct: 186 RHENIAELYGAVLWGETVHLFMEAGEGGSVLEKLESCGPMREFEIIWVTKHVLKGLDFLH 245
Query: 1159 SKGILHRDMKADNLLLDNDGVCKISDFGIS-RKSNNIYSNSDMTMRGTVFWMAPEMVDTA 1217
SK ++H D+K N++ + + DFG+S + + ++Y D +RGT +M+PE++
Sbjct: 246 SKKVIHHDIKPSNIVFMSTKAVLV-DFGLSVQMTEDVYFPKD--LRGTEIYMSPEVI-LC 301
Query: 1218 HGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAA--MFQIGKSKTAPPIPDDTKDLVSPA 1275
G+S K DI+SLG ++ M G PW +A + K APP+ +D D SP
Sbjct: 302 RGHSTKADIYSLGATLIHMQTGTPPWVKRYPRSAYPSYLYIIHKQAPPL-EDIADDCSPG 360
Query: 1276 GQSFLDQCFEIDPEMRPTADSLVGH 1300
+ ++ E +P RP A L+ H
Sbjct: 361 MRELIEASLERNPNHRPRAADLLKH 385
>Hs21359873 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 603
Score = 114 bits (284), Expect = 1e-24
Identities = 73/265 (27%), Positives = 127/265 (47%), Gaps = 13/265 (4%)
Query: 1038 WIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKD 1097
+++G +GKG F + + T E+ A K V + E + E+S +
Sbjct: 53 YVRGRFLGKGGFAKCFEISDADTKEVFAGKIVPKSLLLKPHQR-----EKMSMEISIHRS 107
Query: 1098 LNHVNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYL 1157
L H ++V + GF E N + LE S+ L + + R+ +Q++ G YL
Sbjct: 108 LAHQHVVGFHGFFEDNDFVFVVLELCRRRSLLELHKRRKALTEPEARYYLRQIVLGCQYL 167
Query: 1158 HSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVDTA 1217
H ++HRD+K NL L+ D KI DFG++ K T+ GT ++APE++ +
Sbjct: 168 HRNRVIHRDLKLGNLFLNEDLEVKIGDFGLATKV-EYDGERKKTLCGTPNYIAPEVL-SK 225
Query: 1218 HGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQ 1277
G+S +VD+WS+GC++ + GK P+ + +I K++ + P ++P
Sbjct: 226 KGHSFEVDVWSIGCIMYTLLVGKPPFETSCLKETYLRIKKNEYSIP------KHINPVAA 279
Query: 1278 SFLDQCFEIDPEMRPTADSLVGHPF 1302
S + + + DP RPT + L+ F
Sbjct: 280 SLIQKMLQTDPTARPTINELLNDEF 304
>ECU08g1790 [D] KOG0600 Cdc2-related protein kinase
Length = 309
Score = 114 bits (284), Expect = 1e-24
Identities = 65/207 (31%), Positives = 118/207 (56%), Gaps = 12/207 (5%)
Query: 1044 IGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHVNI 1103
+G+G+FG VY + + G + A+K++ V + +AI ++ KS ++ H+
Sbjct: 10 VGEGAFGQVYKSRRTSDGAVFAIKKMPVDRETGFPFTAIREIKLCKSVIN-----KHIIG 64
Query: 1104 VQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHSKGIL 1163
+ + FEE G + LEY+ G L+ + IR +T Q++E ++ +H G++
Sbjct: 65 LDEIVFEE--GFIFVVLEYMPYDLTG-LLASGAKLSTDQIRSITSQLIEAVSSMHGMGLV 121
Query: 1164 HRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVDTAHGYSAK 1223
HRD+K N+LLD G+ K++DFG++R+ + + +N T+ ++ APE++ YS K
Sbjct: 122 HRDIKPSNILLDCHGMLKLTDFGLTREISGMMTNRVCTL----WYRAPELLLGETSYSLK 177
Query: 1224 VDIWSLGCVVLEMFAGKRPWSNFEVVA 1250
VD WS+GC++LEM G+ P+ + V+
Sbjct: 178 VDAWSVGCIMLEMRLGRPPYRGSDEVS 204
>At5g11850 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 886
Score = 114 bits (284), Expect = 1e-24
Identities = 74/230 (32%), Positives = 122/230 (52%), Gaps = 13/230 (5%)
Query: 1041 GEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNH 1100
GE IG GS+G VY A T +V V +F QD S ++ + KSE+ + L H
Sbjct: 652 GERIGIGSYGEVYRAEWNGT-------EVAVKKFLDQDFSGDALTQ-FKSEIEIMLRLRH 703
Query: 1101 VNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLI-RMYGRFDDQLIRHLTKQVLEGLAYLHS 1159
N+V ++G + +S+ E++ GS+ L+ R + D++ + V +G+ YLH+
Sbjct: 704 PNVVLFMGAVTRPPNFSILTEFLPRGSLYRLLHRPNHQLDEKRRMRMALDVAKGMNYLHT 763
Query: 1160 KG--ILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVDTA 1217
++HRD+K+ NLL+D + V K+ DFG+SR ++ Y +S T GT WMAPE++
Sbjct: 764 SHPTVVHRDLKSPNLLVDKNWVVKVCDFGLSRMKHHTYLSSKST-AGTPEWMAPEVLRNE 822
Query: 1218 HGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDD 1267
+ K D++S G ++ E+ + PW + + +G IPDD
Sbjct: 823 PA-NEKCDVYSFGVILWELATSRVPWKGLNPMQVVGAVGFQNRRLEIPDD 871
>At3g46160 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 393
Score = 114 bits (284), Expect = 1e-24
Identities = 96/325 (29%), Positives = 154/325 (46%), Gaps = 32/325 (9%)
Query: 999 KLQRKNTKMWGTKVVEITDKRTISINKSRNSRGEYKEFAWIKGEIIGKGSFGAVYLALNV 1058
K + +T + T V+E D S + + K W+ +G S +VYLA +
Sbjct: 22 KKLKHSTTISETSVIE--DDADSSTQMGHSIKTIPKSDRWVVTRYLGNSSRSSVYLAEST 79
Query: 1059 TTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHVNIVQYLGFE---EKNG- 1114
GE + +P+ + IS L +E L L + +V + G E EK+G
Sbjct: 80 IEGE-----EDYLPDEMTIKSIEISQASRLMNEEKFLSRLQNPFVVSFYGHEVTIEKDGK 134
Query: 1115 -------IYSLFLEYVAGGSVGSLI-RMYGRFDDQLIRHLTKQVLEGLAYLHSKGILHRD 1166
Y+ EY +G ++ + I + G+ + +R L ++L GL Y+H + I+H D
Sbjct: 135 DPLLEKMYYNTLQEYSSGRNLATHIEKNRGKLPEDDVRSLANEILLGLKYIHEEKIIHCD 194
Query: 1167 MKADNLLL--DNDGVCKISDFGISRKSNNIYSNSDMTMR-GTVFWMAPE-MVDTAHGYSA 1222
+K N++L +N+ +I+ FG + K ++ + R GT + PE M+D Y A
Sbjct: 195 IKPKNIILPFENNLFAQIAGFGKAIKKWSVEYGEGLGHRIGTSRLLPPEVMMDMVLDYGA 254
Query: 1223 KVDIWSLGCVVLEMFAGKRPWSNF---EVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQSF 1279
D+W+ GC VLEM G+R WS F + IG+S + P IP + +S + F
Sbjct: 255 --DVWAFGCTVLEMLTGERVWSEFGKLDWEGWKTLIGESGSVPYIP----NYLSDKAKDF 308
Query: 1280 LDQCFEIDPEMRPTADSLVGHPFCK 1304
L +C E DP R + DSL+ H F K
Sbjct: 309 LAKCLERDPSKRWSVDSLLEHEFLK 333
>At3g08720 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 471
Score = 114 bits (284), Expect = 1e-24
Identities = 69/204 (33%), Positives = 117/204 (56%), Gaps = 12/204 (5%)
Query: 1042 EIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHV 1101
+++G+G+FG VY T E+ A+K + + ++ + E +K+E L ++H
Sbjct: 144 KVVGQGAFGKVYQVRKKDTSEIYAMKVMRKDKIVEKNHA-----EYMKAERDILTKIDHP 198
Query: 1102 NIVQY-LGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHSK 1160
IVQ F+ K +Y L L+++ GG + + G F + L R T +++ +++LH K
Sbjct: 199 FIVQLKYSFQTKYRLY-LVLDFINGGHLFFQLYHQGLFREDLARVYTAEIVSAVSHLHEK 257
Query: 1161 GILHRDMKADNLLLDNDGVCKISDFGISRK-SNNIYSNSDMTMRGTVFWMAPEMVDTAHG 1219
GI+HRD+K +N+L+D DG ++DFG++++ N SNS M GT +MAPE+V G
Sbjct: 258 GIMHRDLKPENILMDVDGHVMLTDFGLAKEFEENTRSNS---MCGTTEYMAPEIV-RGKG 313
Query: 1220 YSAKVDIWSLGCVVLEMFAGKRPW 1243
+ D WS+G ++ EM GK P+
Sbjct: 314 HDKAADWWSVGILLYEMLTGKPPF 337
>At2g17890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand protein
superfamily
Length = 571
Score = 114 bits (284), Expect = 1e-24
Identities = 101/359 (28%), Positives = 176/359 (48%), Gaps = 36/359 (10%)
Query: 966 LTPVKSLKP--PKRTKTIRIIAQEASEARKNEVSQKLQRKNTKMWGT---KVVEITDKR- 1019
LT VKS P P + I ++ R+N ++K ++T G KV+ +R
Sbjct: 27 LTVVKSRPPRSPCSFMAVTIQKDHRTQPRRNATAKKTPTRHTPPHGKVREKVISNNGRRH 86
Query: 1020 --TISINKSRNSRGEYKEF--AWIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFS 1075
TI K R G K+F + G+++G G FG Y+A + TG+ +AVK++
Sbjct: 87 GETIPYGK-RVDFGYAKDFDHRYTIGKLLGHGQFGYTYVATDKKTGDRVAVKKI------ 139
Query: 1076 SQDESAISM---VEALKSEVSTLKDLN-HVNIVQ-YLGFEEKNGIYSLFLEYVAGGSVGS 1130
D++ +++ VE +K EV L+ L H N+V+ Y FE+KN +Y + +E GG +
Sbjct: 140 --DKAKMTIPIAVEDVKREVKILQALTGHENVVRFYNAFEDKNSVY-IVMELCEGGELLD 196
Query: 1131 --LIRMYGRFDDQLIRHLTKQVLEGLAYLHSKGILHRDMKADNLLL---DNDGVCKISDF 1185
L R R+ ++ + +Q+L+ A H +G++HRDMK +N L + D K +DF
Sbjct: 197 RILARKDSRYSERDAAVVVRQMLKVAAECHLRGLVHRDMKPENFLFKSTEEDSPLKATDF 256
Query: 1186 GISRKSNNIYSNSDMTMRGTVFWMAPEMVDTAHGYSAKVDIWSLGCVVLEMFAGKRPWSN 1245
G+S D+ G+ +++APE++ G + D+WS+G + + G+RP+ +
Sbjct: 257 GLSDFIKPGKKFHDIV--GSAYYVAPEVLKRRSG--PESDVWSIGVISYILLCGRRPFWD 312
Query: 1246 FEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQSFLDQCFEIDPEMRPTADSLVGHPFCK 1304
++ K+K P +S + + F+ + DP R TA + HP+ +
Sbjct: 313 KTEDGIFKEVLKNK--PDFRRKPWPTISNSAKDFVKKLLVKDPRARLTAAQALSHPWVR 369
>7298323 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 514
Score = 114 bits (284), Expect = 1e-24
Identities = 81/270 (30%), Positives = 130/270 (48%), Gaps = 14/270 (5%)
Query: 1038 WIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKD 1097
W + +G+G++G V L +N TGE +A+K V + + S ++ EV K
Sbjct: 22 WTLAQTLGEGAYGEVKLLINRQTGEAVAMKMVDLKKHPDAANS-------VRKEVCIQKM 74
Query: 1098 LNHVNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRM---YGRFDDQLIRHLTKQVLEGL 1154
L +I+++ G + + +FLEY AGG + I G + R+ T Q+L GL
Sbjct: 75 LQDKHILRFFGKRSQGSVEYIFLEYAAGGELFDRIGEEPDVGMPQHEAQRYFT-QLLSGL 133
Query: 1155 AYLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMR-GTVFWMAPEM 1213
YLH +GI HRD+K +NLLLD KISDFG++ + R GT+ ++APE+
Sbjct: 134 NYLHQRGIAHRDLKPENLLLDEHDNVKISDFGMATMFRCKGKERLLDKRCGTLPYVAPEV 193
Query: 1214 VDTAHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVS 1273
+ A+ ++ D+WS G +++ M AG+ PW F + + L +
Sbjct: 194 LQKAY-HAQPADLWSCGVILVTMLAGELPWDQPSTNCTEFTNWRDNDHWQLQTPWSKLDT 252
Query: 1274 PAGQSFLDQCFEIDPEMRPTADSLVGHPFC 1303
A S L + P R T + + H +C
Sbjct: 253 LA-ISLLRKLLATSPGTRLTLEKTLDHKWC 281
>Hs8923922 [R] KOG0586 Serine/threonine protein kinase
Length = 795
Score = 113 bits (283), Expect = 2e-24
Identities = 70/200 (35%), Positives = 106/200 (53%), Gaps = 8/200 (4%)
Query: 1044 IGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHVNI 1103
IGKG+F V LA +V TG +AVK + + + + ++ L EV +K LNH NI
Sbjct: 66 IGKGNFAKVKLARHVLTGREVAVKIIDKTQLNP------TSLQKLFREVRIMKILNHPNI 119
Query: 1104 VQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHSKGIL 1163
V+ E L +EY +GG V + +GR ++ R +Q++ + Y H K I+
Sbjct: 120 VKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIV 179
Query: 1164 HRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVDTAHGYSAK 1223
HRD+KA+NLLLD D KI+DFG S + N T G+ + APE+ +
Sbjct: 180 HRDLKAENLLLDGDMNIKIADFGFSNEFT--VGNKLDTFCGSPPYAAPELFQGKKYDGPE 237
Query: 1224 VDIWSLGCVVLEMFAGKRPW 1243
VD+WSLG ++ + +G P+
Sbjct: 238 VDVWSLGVILYTLVSGSLPF 257
>CE27297 [D] KOG0615 Serine/threonine protein kinase Chk2 and related proteins
Length = 476
Score = 113 bits (283), Expect = 2e-24
Identities = 83/269 (30%), Positives = 136/269 (49%), Gaps = 15/269 (5%)
Query: 1044 IGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHVNI 1103
+GKG FG V L + ++A+KQ+ +FS++ AI+ +++EV +K L+H NI
Sbjct: 176 LGKGGFGKVLLGYKKSDRSVVAIKQLNT-QFSTRCSRAIAKTRDIRNEVEVMKKLSHPNI 234
Query: 1104 VQYLGFEEKNGIYSLFLEYVAGGSVGSLI--RMYGRFD--DQLIRHLTKQVLEGLAYLHS 1159
V + + +EYV GG S + Y R + L ++ Q+++ + YLHS
Sbjct: 235 VAIYDWITVAKYSYMVIEYVGGGEFFSKVVDSKYNRMGLGESLGKYFAFQLIDAILYLHS 294
Query: 1160 KGILHRDMKADNLLLDNDG---VCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMV-D 1215
GI HRD+K +N+L + + K++DFG+++ S N T GT + APE+V +
Sbjct: 295 VGICHRDIKPENILCSDKAERCILKLTDFGMAKNSVNRMK----TRCGTPSYNAPEIVAN 350
Query: 1216 TAHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPA 1275
Y+ KVDIWSLGCV+ F+G P+S E M + T I ++
Sbjct: 351 EGVEYTPKVDIWSLGCVLFITFSGYPPFS--EEYTDMTMDEQVLTGRLIFHAQWRRITVE 408
Query: 1276 GQSFLDQCFEIDPEMRPTADSLVGHPFCK 1304
Q+ + ++P RP+A L+ + K
Sbjct: 409 TQNMIKWMLTVEPSNRPSAVELMSTQWMK 437
>At3g06630 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 671
Score = 113 bits (283), Expect = 2e-24
Identities = 79/247 (31%), Positives = 126/247 (50%), Gaps = 17/247 (6%)
Query: 1041 GEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNH 1100
GE IG+GS G VY + G +AVK + E+S S++++ + EVS +K L H
Sbjct: 437 GEQIGRGSCGTVYHG--IWFGSDVAVKVFSKQEYSE------SVIKSFEKEVSLMKRLRH 488
Query: 1101 VNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLI-RMYGRFDDQLIRHLTKQVLEGLAYLH- 1158
N++ ++G + E+V GS+ L+ R + D + ++ + G+ YLH
Sbjct: 489 PNVLLFMGAVTSPQRLCIVSEFVPRGSLFRLLQRSMSKLDWRRRINMALDIARGMNYLHC 548
Query: 1159 -SKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVDTA 1217
S I+HRD+K+ NLL+D + K++DFG+SR + Y S + +GT WMAPE++
Sbjct: 549 CSPPIIHRDLKSSNLLVDRNWTVKVADFGLSRIKHQTYLTS-KSGKGTPQWMAPEVLRN- 606
Query: 1218 HGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIPDDTKDLVSPAGQ 1277
K DI+S G V+ E+ K PW N + + +G IP DT P
Sbjct: 607 ESADEKSDIYSFGVVLWELATEKIPWENLNSMQVIGAVGFMNQRLEIPKDT----DPDWI 662
Query: 1278 SFLDQCF 1284
S ++ C+
Sbjct: 663 SLIESCW 669
>At2g17700 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 546
Score = 113 bits (283), Expect = 2e-24
Identities = 67/227 (29%), Positives = 115/227 (50%), Gaps = 8/227 (3%)
Query: 1073 EFSSQDESAISMVEALKSEVSTLKDLNHVNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLI 1132
+F D M+ EV ++ + H N+VQ+LG ++ + E++A GS+ +
Sbjct: 313 KFLKPDRVNNEMLREFSQEVFIMRKVRHKNVVQFLGACTRSPTLCIVTEFMARGSIYDFL 372
Query: 1133 -RMYGRFDDQLIRHLTKQVLEGLAYLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKS 1191
+ F Q + + V +G++YLH I+HRD+K NLL+D G+ K++DFG++R
Sbjct: 373 HKQKCAFKLQTLLKVALDVAKGMSYLHQNNIIHRDLKTANLLMDEHGLVKVADFGVARV- 431
Query: 1192 NNIYSNSDMTMRGTVFWMAPEMVDTAHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAA 1251
I S GT WMAPE+++ Y+ K D++S V+ E+ G P++ + A
Sbjct: 432 -QIESGVMTAETGTYRWMAPEVIE-HKPYNHKADVFSYAIVLWELLTGDIPYAFLTPLQA 489
Query: 1252 MFQIGKSKTAPPIPDDTKDLVSPAGQSFLDQCFEIDPEMRPTADSLV 1298
+ + P IP T P + L++C+ DPE RP + ++
Sbjct: 490 AVGVVQKGLRPKIPKKT----HPKVKGLLERCWHQDPEQRPLFEEII 532
>7299437 [R] KOG0586 Serine/threonine protein kinase
Length = 604
Score = 113 bits (283), Expect = 2e-24
Identities = 82/274 (29%), Positives = 138/274 (49%), Gaps = 25/274 (9%)
Query: 1028 NSRGEYKEFAWIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMV-- 1085
N G YK + +GKG+F V LA+++ TG +A+K + D++A++ +
Sbjct: 58 NGYGVYKII-----KTLGKGNFAKVKLAIHLPTGREVAIKLI--------DKTALNTIAR 104
Query: 1086 EALKSEVSTLKDLNHVNIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRH 1145
+ L EV+ +K LNH NIV+ L E L +EYV+GG + + + GR ++ R
Sbjct: 105 QKLYREVNIMKKLNHPNIVRLLQVIESERTLYLVMEYVSGGELFNYLVKNGRMRERDARV 164
Query: 1146 LTKQVLEGLAYLHSKGILHRDMKADNLLLDNDGVCKISDFGISRKSNNIYSNSDM-TMRG 1204
L +Q++ + Y HSK I+HRD+KA+NLLLD KI+DFG S + + T G
Sbjct: 165 LFRQLVSAIEYCHSKSIVHRDLKAENLLLDQQMKLKIADFGF---STTFEPKAPLETFCG 221
Query: 1205 TVFWMAPEMVDTAHGYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPI 1264
+ + APE+ +VD WSLG V+ + +G P+ + ++ + K P
Sbjct: 222 SPPYAAPELFRGKKYSGPEVDSWSLGVVLYTLVSGSLPFDGTNLKELRDRVLRGKYRVPY 281
Query: 1265 PDDTKDLVSPAGQSFLDQCFEIDPEMRPTADSLV 1298
VS +S + + ++P R + +++
Sbjct: 282 ------YVSIECESLIRKFLVLNPTQRTSLSAVM 309
>YBR028c [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 525
Score = 113 bits (282), Expect = 2e-24
Identities = 90/345 (26%), Positives = 159/345 (46%), Gaps = 56/345 (16%)
Query: 953 PAFLSSRGESSQFLTPVKSLKPPKRTKTIRIIAQEASEARKNEVSQKLQRKNTKMWGTKV 1012
PA R S+ P+ L PP T+ I +A N +S
Sbjct: 64 PAHRMRRRSSAYSKFPI--LTPPN-TRRFSITGSDAMRTNTNRLS--------------- 105
Query: 1013 VEITDKRTISINKSRNSRGE-YKEFAWIKGEIIGKGSFGAVYLALNVTTGEMLAVKQVTV 1071
IT + IS N N +F ++ ++G+G++G V L +V T ++ A+KQ+
Sbjct: 106 --ITPQDIISSNIGENELSRNLHDFKPVR--VLGQGAYGKVLLVKDVNTSKLYAMKQLRK 161
Query: 1072 PEF---------------------SSQDESAISMVEALKSEVSTLKDLNHVNIVQ-YLGF 1109
E + D+ +E +E S L ++ H NIV+ + F
Sbjct: 162 AEILISQTATDSKREDEDKNDGNNNDNDDGLSKRLERTFAERSILSEIEHPNIVKLFYSF 221
Query: 1110 EEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHSKGILHRDMKA 1169
+ + +Y L L+Y+ GG + ++ +G D+ + ++ L +LH+KG+++RD+K
Sbjct: 222 HDNSKLY-LLLQYIPGGELFYHLKEHGTLDETTVSFYAAEISCALRFLHTKGVVYRDLKP 280
Query: 1170 DNLLLDNDGVCKISDFGISRKSNNIYS---------NSDMTMRGTVFWMAPEMVDTAHGY 1220
+N LL+ G ++DFG+S+KS N + N+ ++ GT + APE++ Y
Sbjct: 281 ENCLLNQRGHLVLTDFGLSKKSANDSAVDEEDPENVNALYSIIGTPEYCAPEIL-LGKAY 339
Query: 1221 SAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTAPPIP 1265
S D +SLGC++ +M GK P++ + +I ++K P IP
Sbjct: 340 SQNCDWYSLGCLLYDMLVGKPPYTGSNHKVIINKIQQNKQGPKIP 384
>Hs4502553 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand protein
superfamily
Length = 370
Score = 113 bits (282), Expect = 2e-24
Identities = 81/274 (29%), Positives = 135/274 (48%), Gaps = 19/274 (6%)
Query: 1042 EIIGKGSFGAVYLALNVTTGEMLAVKQVTVPEFSSQDESAISMVEALKSEVSTLKDLNHV 1101
+++G G+F V LA + T +++A+K + ++ S +++E++ L + H
Sbjct: 24 DVLGTGAFSEVILAEDKRTQKLVAIKCIAKEALEGKEGS-------MENEIAVLHKIKHP 76
Query: 1102 NIVQYLGFEEKNGIYSLFLEYVAGGSVGSLIRMYGRFDDQLIRHLTKQVLEGLAYLHSKG 1161
NIV E G L ++ V+GG + I G + ++ L QVL+ + YLH G
Sbjct: 77 NIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLG 136
Query: 1162 ILHRDMKADNLL---LDNDGVCKISDFGISRKSNNIYSNSDMTMRGTVFWMAPEMVDTAH 1218
I+HRD+K +NLL LD D ISDFG+S+ + + T GT ++APE++
Sbjct: 137 IVHRDLKPENLLYYSLDEDSKIMISDFGLSKMEDP--GSVLSTACGTPGYVAPEVL-AQK 193
Query: 1219 GYSAKVDIWSLGCVVLEMFAGKRPWSNFEVVAAMFQIGKSKTA--PPIPDDTKDLVSPAG 1276
YS VD WS+G + + G P+ + QI K++ P DD +S +
Sbjct: 194 PYSKAVDCWSIGVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDD----ISDSA 249
Query: 1277 QSFLDQCFEIDPEMRPTADSLVGHPFCKTSSSFD 1310
+ F+ E DPE R T + + HP+ ++ D
Sbjct: 250 KDFIRHLMEKDPEKRFTCEQALQHPWIAGDTALD 283
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.312 0.129 0.362
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 70,907,019
Number of Sequences: 60738
Number of extensions: 2902986
Number of successful extensions: 13833
Number of sequences better than 1.0e-05: 1863
Number of HSP's better than 0.0 without gapping: 556
Number of HSP's successfully gapped in prelim test: 1307
Number of HSP's that attempted gapping in prelim test: 8913
Number of HSP's gapped (non-prelim): 2489
length of query: 1338
length of database: 30,389,216
effective HSP length: 119
effective length of query: 1219
effective length of database: 23,161,394
effective search space: 28233739286
effective search space used: 28233739286
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)