ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI3871 good A KOG1919 RNA processing and modification RNA pseudouridylate synthases
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI3871 1350504 1351634 377
(377 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YGR169c [A] KOG1919 RNA pseudouridylate synthases 323 2e-88
YOL066c_1 [A] KOG1919 RNA pseudouridylate synthases 228 9e-60
YDL036c [A] KOG1919 RNA pseudouridylate synthases 218 9e-57
SPAC18B11.02c [A] KOG1919 RNA pseudouridylate synthases 200 3e-51
Hs17478211 [A] KOG1919 RNA pseudouridylate synthases 195 8e-50
7297707 [A] KOG1919 RNA pseudouridylate synthases 186 6e-47
7297709 [A] KOG1919 RNA pseudouridylate synthases 180 3e-45
At5g51140 [A] KOG1919 RNA pseudouridylate synthases 161 1e-39
CE11898 [A] KOG1919 RNA pseudouridylate synthases 138 1e-32
ECU05g0680 [A] KOG1919 RNA pseudouridylate synthases 106 5e-23
At3g52260 [A] KOG1919 RNA pseudouridylate synthases 75 1e-13
Hs20481524 [A] KOG1919 RNA pseudouridylate synthases 73 6e-13
Hs14249470 [A] KOG1919 RNA pseudouridylate synthases 73 6e-13
Hs17158025 [A] KOG1919 RNA pseudouridylate synthases 67 3e-11
At3g19440 [A] KOG1919 RNA pseudouridylate synthases 53 8e-07
>YGR169c [A] KOG1919 RNA pseudouridylate synthases
Length = 404
Score = 323 bits (829), Expect = 2e-88
Identities = 183/398 (45%), Positives = 236/398 (58%), Gaps = 33/398 (8%)
Query: 8 MSIYFQNGLRKIAPYYNARSSFVKGRWFGKSLTQIFIDEFAHTHEEAQL-KITEGFIKLL 66
+ +Y QNGLRK+ PYYN RS+FVKGRW GK L + + EF L +I +G +L+
Sbjct: 7 IEVYTQNGLRKVRPYYNRRSAFVKGRWLGKLLIDVLVSEFKLRPRAYYLDQIRKGTYRLI 66
Query: 67 REGKQLEGD----PIIKNKDILLTYQHNHEPPVKNWGEPICDEK----HIMGIPIVHQDE 118
R+G L D IIKN D+L T H HEPPVK W + + I G IV +DE
Sbjct: 67 RDGVPLVPDHLMTTIIKNHDVLETTTHKHEPPVKQWCSQEVEAEDLPGRIAGFNIVFEDE 126
Query: 119 QLLVINKPNGIPVHPTAYFYKNTLTELLKDSLGYPVHPCYRLDKITSGLLILAKNPIDAN 178
+LVI+KP+GIPVHPT FY+NT+TELLK G PCYRLDKITSGLLILAKN A
Sbjct: 127 SILVIDKPSGIPVHPTGQFYQNTITELLKLH-GVDALPCYRLDKITSGLLILAKNSQSAG 185
Query: 179 RVQSKIRDRDMKKYYLARVKGKFPET--------------------AVDKSPIYTCDLKI 218
+Q IR RDM K YLARVKG+FP + V+ +PIY+ D K
Sbjct: 186 EIQKSIRSRDMIKIYLARVKGRFPHSELILDNENAAETTFEDTSKVTVEMTPIYSIDPKR 245
Query: 219 KSEP-LSPLKDAHTEFELMEYDAVTDQSIVLCKPFTGRTHQIRIHLARQGHPITNDPFYN 277
+ LS KDA T+F + Y + D+++V CKP TGRTHQIRIHLAR GHPI ND Y
Sbjct: 246 QFPVGLSTSKDAITKFYPIRYFSHADETVVACKPITGRTHQIRIHLARLGHPIVNDSVYC 305
Query: 278 LDNSTYPLRSRFIIETPDWTQLTNERIEKLRKRFEVELDDVWDQLNENQERCPECDEEMP 337
+ YP R +FI + P W + E+L+ RF+ +D+ + + CPEC
Sbjct: 306 SHITKYPERLKFITQFPRWENQQDLDAEELKVRFQKFVDETKNNCRTMETFCPECHTVDL 365
Query: 338 KDPTPESLELYLHAWRYKGLD--LEFETDYPYWAKFEN 373
KDP LEL+LHAW+Y+ ++ +F+TD P WA+ +N
Sbjct: 366 KDPVLSDLELWLHAWKYEEINGKFKFKTDLPKWAQLDN 403
>YOL066c_1 [A] KOG1919 RNA pseudouridylate synthases
Length = 434
Score = 228 bits (582), Expect = 9e-60
Identities = 141/377 (37%), Positives = 201/377 (52%), Gaps = 33/377 (8%)
Query: 5 EEEMSIYFQNGLRKIAPYYNARSSFVKGRWFGKSLTQIFIDEFAHTHEEAQLK-ITEGFI 63
+ + + LRKI PY+ +F K RW + L +F+ EF K I EG +
Sbjct: 67 DPDYEVTIDGPLRKIEPYFFTYKTFCKERWRDRKLVDVFVSEFRDREPSYYSKTIAEGKV 126
Query: 64 KLLREGKQLEGDPIIKNKDILLTYQHNHEPPVKNWGEPICDEKHIMGIPIVHQDEQLLVI 123
L E L D II++ D++ H HEPPV + I IV +DE +LVI
Sbjct: 127 YLNDEPANL--DTIIRDGDLITHKVHRHEPPVTS-----------KPIDIVFEDEDILVI 173
Query: 124 NKPNGIPVHPTAYFYKNTLTELLKDSLGYPVHPCYRLDKITSGLLILAKNPIDANRVQSK 183
+KP+ IPVHPT + NT+T++L+ LGY VHPC RLDK TSGL+ LAK P+ A+R+ +
Sbjct: 174 DKPSSIPVHPTGRYRFNTITKMLERQLGYSVHPCNRLDKPTSGLMFLAKTPLGADRMGDQ 233
Query: 184 IRDRDMKKYYLARVKGKFPETAVD-KSPIYTCDLKIKSEPLSPLKD-----AHTEFELME 237
++ R++ K Y+ARVKG+FP V+ P+ + + K+ + + D A T F+ +
Sbjct: 234 MKAREVTKEYVARVKGEFPIGIVEVDKPVRSVNPKVALNAVCEMSDENAKHAKTVFQRVS 293
Query: 238 YDAVTDQSIVLCKPFTGRTHQIRIHLARQGHPITNDPFYNLDNSTYPLRSRFIIETPDWT 297
YD T SIV CKP TGRTHQIR+HL G PI NDP Y+ + P R ++ D
Sbjct: 294 YDGQT--SIVKCKPLTGRTHQIRVHLQYLGFPIANDPIYSNPDIWGPDLGRGGLQNYDDI 351
Query: 298 QLTNERIEKLRKRFEVELDDVWDQLNENQE-----RCPECDEEMPKDPTPESLELYLHAW 352
L + I K + W + E +C EC+ EM DP L+L+LHA+
Sbjct: 352 VLKLDAIGKTNPA------ESWIHPHSEGEYLLGRQCEECEAEMYTDPGTNDLDLWLHAF 405
Query: 353 RYKGLDLEFETDYPYWA 369
RY+ L+ +T P W+
Sbjct: 406 RYESLERNSDTQKPLWS 422
>YDL036c [A] KOG1919 RNA pseudouridylate synthases
Length = 462
Score = 218 bits (556), Expect = 9e-57
Identities = 134/393 (34%), Positives = 209/393 (53%), Gaps = 53/393 (13%)
Query: 4 LEEEMSIYFQNGLRKIAPYYNARSSFVKGRWFGKSLTQIFIDEFAHTHEEAQLKITE-GF 62
L+ E I LRKI PY+ +F K RW K L +FI EF E + E G
Sbjct: 93 LDPEYEIVIDGPLRKIKPYHFTYRTFCKERWRDKKLVDVFISEFRDRESEYYKRTIENGD 152
Query: 63 IKLLREGKQLEGDPIIKNKDILLTYQHNHEPPVKNWGEPICDEKHIMGIPIVHQDEQLLV 122
+ + E L +I+N D++ H HEPPV + I ++ +D+ ++V
Sbjct: 153 VHINDETADLS--TVIRNGDLITHQVHRHEPPVTS-----------RPIKVIFEDDNIMV 199
Query: 123 INKPNGIPVHPTAYFYKNTLTELLKDSLGYPVHPCYRLDKITSGLLILAKNPIDANRVQS 182
I+KP+GIPVHPT + NT+T++L+++LG+ V+PC RLD++TSGL+ LAK P A+ +
Sbjct: 200 IDKPSGIPVHPTGRYRFNTITKMLQNNLGFVVNPCNRLDRLTSGLMFLAKTPKGADNIGD 259
Query: 183 KIRDRDMKKYYLARVKGKFPET-AVDKSPIYTCDLKIKSEPLSPL-----KDAHTEFELM 236
+++ R++ K Y+A+V G+FPET + + P+ + ++ + + K A T F +
Sbjct: 260 QLKAREVTKEYVAKVVGEFPETEVIVEKPLKLIEPRLALNAVCQMDEKGAKHAKTVFNRI 319
Query: 237 EYDAVTDQSIVLCKPFTGRTHQIRIHLARQGHPITNDPFYNLD-----NSTYPLRSRFII 291
YD T SIV CKP TGR+HQIR+HL GHPI NDP Y+ D N ++ F
Sbjct: 320 SYDGKT--SIVKCKPLTGRSHQIRVHLQYLGHPIANDPIYSNDEVWGNNLGKGGQADF-- 375
Query: 292 ETPDWTQLTNERIEKLRKRFEVELDDVWDQLNE------NQERCPECDEEMPKDPTPESL 345
+ +++++ KR + W N QE+C C+ ++ DP P L
Sbjct: 376 ------DIVITKLDEIGKRKPAK---SWFHSNGGYGEVLRQEKCSICESDLYTDPGPNDL 426
Query: 346 ELYLHAWRYKGLDLE---------FETDYPYWA 369
+L+LHA+ Y+ + E ++T+YP WA
Sbjct: 427 DLWLHAYLYESTETEEGTEKKKWCYKTEYPEWA 459
>SPAC18B11.02c [A] KOG1919 RNA pseudouridylate synthases
Length = 394
Score = 200 bits (508), Expect = 3e-51
Identities = 128/385 (33%), Positives = 203/385 (52%), Gaps = 45/385 (11%)
Query: 10 IYFQNGLRKIAPYYNARSSFVKGRWFGKSLTQIFIDEFAHTHEEAQLK-ITEGFIKLLRE 68
++ +GLR++ PYY +F K RW+GK+L ++F EF K I G +K+ +
Sbjct: 16 VFKGDGLRRVPPYYYEYITFAKLRWYGKTLLEVFNTEFRDRESGYYEKAIRNGQVKVNNQ 75
Query: 69 GKQLEGDPIIKNKDILLTYQHNHEPPVKNWGEPICDEKHIMGIPIVHQDEQLLVINKPNG 128
+ D +I+N I+ + H HEPPV + + IVH+DE +VI+KP G
Sbjct: 76 IGNV--DTLIENGYIVSHHAHRHEPPVSD-----------QPVGIVHEDESYVVIDKPAG 122
Query: 129 IPVHPTAYFYKNTLTELL-KDSLGYPVHPCYRLDKITSGLLILAKNPIDANRVQSKIRDR 187
+PVHPT + NT+ +L K++ ++PC RLD++TSGL+ +K+P A ++ + +
Sbjct: 123 VPVHPTGRYNHNTVLHILMKENKCSLLYPCNRLDRLTSGLMFFSKSPKAAEEMRVHMISK 182
Query: 188 DMKKYYLARVKGKFPETA--VDKSPIYTCDLKIKSEPLSPL-KDAHTEFELMEYDAVTDQ 244
+KK Y+ARV G+FP + + +P+ T + + P K+A T F+ + +D T
Sbjct: 183 SLKKEYVARVIGEFPNSGEVICDAPLLTVAPTLGLNRIHPDGKEASTVFKRIAFDGHT-- 240
Query: 245 SIVLCKPFTGRTHQIRIHLARQGHPITNDPFY--------------NLDNSTYPLRSRFI 290
S+VLCKP TGRTHQ+R+HL G+PI NDP Y N + +R I
Sbjct: 241 SLVLCKPLTGRTHQLRVHLQYLGYPIANDPIYANKRVWGPSLGKNGEGSNESVIMRLSEI 300
Query: 291 IETPDWTQL------TNERIEKLRKRFEVELDDVWDQLNENQERCPECDEEMPKDPTPES 344
+T + L TNE + + R + L ++ + C EC + DP+PE
Sbjct: 301 GKTETASPLLQYEWYTNETEAEAKARRDKRLGELL-----TGKHCSECGTPLYSDPSPEE 355
Query: 345 LELYLHAWRYKGLDLEFETDYPYWA 369
L ++LHA +Y+ D ++T P WA
Sbjct: 356 LGIWLHALKYESKDWSYKTQLPKWA 380
>Hs17478211 [A] KOG1919 RNA pseudouridylate synthases
Length = 545
Score = 195 bits (496), Expect = 8e-50
Identities = 141/430 (32%), Positives = 209/430 (47%), Gaps = 76/430 (17%)
Query: 7 EMSIYFQNGLRKIAPYYNARSSFVKGRWFGKSLTQIFIDEF-AHTHEEAQLKITEGFIKL 65
E S YF+ GLRK+ PYY ++ KGRW G SL +F EF A + + G ++L
Sbjct: 130 ETSYYFEGGLRKVRPYYFDFRTYCKGRWVGHSLLHVFSTEFRAQPLAYYEAAVRAGRLQL 189
Query: 66 LREGKQLEGDPIIKNKDILLTYQHNHEPPVKNWGEPICDEKHIMGIPIVHQDEQLLVINK 125
+ Q + + ++K+ D L H HEPPV EPI ++ ++E ++V++K
Sbjct: 190 NEKPVQ-DLNIVLKDNDFLRNTVHRHEPPVT--AEPI---------RLLAENEDVVVVDK 237
Query: 126 PNGIPVHPTAYFYKNTLTELL-KDSLGYPVHPCYRLDKITSGLLILAKNPIDANRVQSKI 184
P+ IPVHP F NT+ +L K+ +HP +RLD++TSG+L+ AK + R+ ++
Sbjct: 238 PSSIPVHPCGRFRHNTVIFILGKEHQLKELHPLHRLDRLTSGVLMFAKTAAVSERIHEQV 297
Query: 185 RDRDMKKYYLARVKGKFP-ETAVDKSPIYTCDLKIKSEPLSPL-KDAHTEFELMEYDAVT 242
RDR ++K Y+ RV+G+FP E K PI K+ + P K T F+ + Y+
Sbjct: 298 RDRQLEKEYVCRVEGEFPTEEVTCKEPILVVSYKVGVCRVDPRGKPCETVFQRLSYNG-- 355
Query: 243 DQSIVLCKPFTGRTHQIRIHLARQGHPITNDPFYN------------------------- 277
S+V C+P TGRTHQIR+HL GHPI NDP YN
Sbjct: 356 QSSVVRCRPLTGRTHQIRVHLQFLGHPILNDPIYNSVAWGPSRGRGGYIPKTNEELLRDL 415
Query: 278 ------------LDNSTYPLRSRFIIETPDWTQLTNERIEKL----RKRFEV------EL 315
LD L T ++L + +E+L +K EV EL
Sbjct: 416 VAEHQAKQSLDVLDLCEGDLSPGLTDSTAPSSELGKDDLEELAAAAQKMEEVAEAAPQEL 475
Query: 316 DDV---------WDQLN-ENQERCPECDEEMPKDPTPESLELYLHAWRYKGLDLEFETDY 365
D + D +N E C EC + +DP P+ L ++LHA RYKG E+ +
Sbjct: 476 DTIALASEKAVETDVMNQETDPLCAEC-RLVRQDPLPQDLVMFLHALRYKGPGFEYFSPM 534
Query: 366 PYWAKFENEK 375
P WA+ + +K
Sbjct: 535 PAWAQDDWQK 544
>7297707 [A] KOG1919 RNA pseudouridylate synthases
Length = 506
Score = 186 bits (471), Expect = 6e-47
Identities = 110/276 (39%), Positives = 155/276 (55%), Gaps = 19/276 (6%)
Query: 6 EEMSIYFQNGLRKIAPYYNARSSFVKGRWFGKSLTQIFIDEF-AHTHEEAQLKITEGFIK 64
+E S Y +NGLRK+ PYY ++F KGRW G+ + IF EF AH EE + I G +
Sbjct: 56 QETSYYMENGLRKVYPYYFTFTTFTKGRWVGEKILDIFSREFRAHPAEEYERCIQTGTLT 115
Query: 65 LLREGKQLEGDPIIKNKDILLTYQHNHEPPVKNWGEPICDEKHIMGIPIVHQDEQLLVIN 124
+ E + D +K+ D+L H HE PV I IVH DE ++V+N
Sbjct: 116 VNFEKVPI--DYRLKHNDLLANIVHRHEVPVT-----------CQPIKIVHMDEDIVVVN 162
Query: 125 KPNGIPVHPTAYFYKNTLTELLKDSLGYP-VHPCYRLDKITSGLLILAKNPIDANRVQSK 183
KP IPVHP + NT+ +L + +RLD++TSGLL+ ++P A +++ +
Sbjct: 163 KPASIPVHPCGRYRHNTVVFILAKEFNLKNLRTIHRLDRLTSGLLLFGRSPKKARQMEQQ 222
Query: 184 IRDRDMKKYYLARVKGKFPETAVD-KSPIYTCDLKIKSEPLSPL-KDAHTEFELMEYDAV 241
IR+R ++K Y+ RV+G FP+ V+ K PI KI +S KD T F+ + +
Sbjct: 223 IRNRQVEKEYICRVEGVFPDGIVECKEPIEVVSYKIGVCKVSAKGKDCTTTFQKLSQNGT 282
Query: 242 TDQSIVLCKPFTGRTHQIRIHLARQGHPITNDPFYN 277
T S+VLCKP TGR HQIR+HL G+PI NDP YN
Sbjct: 283 T--SVVLCKPLTGRMHQIRVHLQYLGYPILNDPLYN 316
>7297709 [A] KOG1919 RNA pseudouridylate synthases
Length = 569
Score = 180 bits (456), Expect = 3e-45
Identities = 132/402 (32%), Positives = 190/402 (46%), Gaps = 75/402 (18%)
Query: 6 EEMSIYFQNGLRKIAPYYNARSSFVKGRWFGKSLTQIFIDEF-AHTHEEAQLKITEGFIK 64
+E S YF+NGLRK+ PY+ ++F KGRW + + +F+ EF A EE + + G K
Sbjct: 177 DETSYYFENGLRKVYPYFFTFTTFAKGRWVDEKILDVFVREFRAAPPEEYERSLEAG--K 234
Query: 65 LLREGKQLEGDPIIKNKDILLTYQHNHEPPVKNWGEPICDEKHIMGIPIVHQDEQLLVIN 124
L +++ D IK+ D+L H HE PV + I IV+ D+ ++V+N
Sbjct: 235 LTVNSEKVPKDYKIKHNDLLANVVHRHEVPVTS-----------QPIKIVYMDKDIVVVN 283
Query: 125 KPNGIPVHPTAYFYKNTLTELL-KDSLGYPVHPCYRLDKITSGLLILAKNPIDANRVQSK 183
KP IPVHP + NT+ +L K+ + +RLD++TSGLL+ + A ++ +
Sbjct: 284 KPASIPVHPCGRYRHNTVVFILAKEHNLKNLRTIHRLDRLTSGLLLFGRTAEKARELELQ 343
Query: 184 IRDRDMKKYYLARVKGKFPETAVD-KSPIYTCDLKIKSEPLSPL-KDAHTEFELMEYDAV 241
IR R ++K Y+ RV+G+FP+ V+ I KI +SP KD T F+ + V
Sbjct: 344 IRTRQVQKEYVCRVEGRFPDGIVECNEKIDVVSYKIGVCKVSPKGKDCKTTFKRI--GEV 401
Query: 242 TDQSIVLCKPFTGRTHQIRIHLARQGHPITNDPFYNLDNSTYPLRSR------------- 288
SIVLCKP TGR HQIR+HL G+PI+NDP YN PL+ R
Sbjct: 402 GSDSIVLCKPLTGRMHQIRVHLQFLGYPISNDPLYN-HEVFGPLKGRGGDIGGITEEQLI 460
Query: 289 --------------------------------FIIETPDWTQL-TNERIEK--LRKRFEV 313
++E P Q N EK + K E
Sbjct: 461 SNLISIHNAENWLGLEGDQIVSGEIKDVAASTSVVEAPSVVQAPINSETEKPVISKNLEP 520
Query: 314 ELDDVWDQLNENQERCPECDEEMPKDPTPESLELYLHAWRYK 355
D D +C EC +DP + L +YLHAW+YK
Sbjct: 521 SNDTTSD------PQCSECKINY-RDPGTKDLIMYLHAWKYK 555
>At5g51140 [A] KOG1919 RNA pseudouridylate synthases
Length = 395
Score = 161 bits (408), Expect = 1e-39
Identities = 120/390 (30%), Positives = 186/390 (46%), Gaps = 61/390 (15%)
Query: 4 LEEEMSIYFQNGLRKIAPYYNARSSFVKGRWFGKSLTQIFIDEFAHTHEEAQL-KITEGF 62
L ++ F G R + PYY S V RW GK++ +F DEF + + + G
Sbjct: 41 LSQKQDYIFHGGRRHVRPYYFEFISHVNKRWTGKTIVDLFADEFKGRPRDYYVGAVKSGR 100
Query: 63 IKLLREGKQLEGDPIIKNKDILLTYQHNHEPPVKNWGEPICDEKHIMGIPIVHQDEQLLV 122
IK+ +G+ + I+K+ + + H HEPPV I + I+HQ+ ++
Sbjct: 101 IKV--DGEIVPVSYIVKSSQKITHFLHRHEPPVM-----------IDDVVILHQEPDVVT 147
Query: 123 INKPNGIPVHPTAYFYKNTLTELL--KDSLGYPVHPCYRLDKITSGLLILAKNPIDANRV 180
+ KP +PVHP + KNT+ +L + LG + P +RLD++ SGLLI+A+ A+
Sbjct: 148 VCKPASVPVHPCGQYRKNTIVGILDAEHDLG-TLFPIHRLDRLVSGLLIIARTAAKADFF 206
Query: 181 QSKIRDRDMKKYYLARVKGKFPETA--VDKSPIYTC---------------DLKIKSEPL 223
+ +I +KK Y+A+V G FPE VD + Y D K+K +P
Sbjct: 207 RQQIEGGMVKKRYIAKVIGVFPEDEMIVDANINYNGSEGRSTAEDANSSGDDKKVKGKP- 265
Query: 224 SPLKDAHTEFELMEYDAVTDQSIVLCKPFTGRTHQIRIHLARQGHPITNDPFY---NLDN 280
A T+F ++ + S+V C+P TGRTHQIR+HL GHPI NDP Y ++DN
Sbjct: 266 -----ACTKFTRIDTNGT--HSLVSCEPVTGRTHQIRVHLQYTGHPIANDPLYLNQHIDN 318
Query: 281 STYPLRSRFIIETPDWTQLTNERIEKLRKRFEVELDDVWDQLNEN-QERCPECDEEMPKD 339
+ET +RI+ ++ D V+ + + C C + +P+
Sbjct: 319 ----------LET-----YIAKRIDAGERKIVSPDDYVYSSEDFSIDPMCTNCPKLIPQG 363
Query: 340 PTPESLELYLHAWRYKGLDLEFETDYPYWA 369
L+LH +Y G E+E YP WA
Sbjct: 364 YEEHDEALWLHCVQYCGTGWEYECPYPSWA 393
>CE11898 [A] KOG1919 RNA pseudouridylate synthases
Length = 432
Score = 138 bits (348), Expect = 1e-32
Identities = 107/383 (27%), Positives = 176/383 (45%), Gaps = 42/383 (10%)
Query: 14 NGLRKIAPYYNARSSFVKGRWFGKSLTQIFIDEFAHTHEEAQLKITEGFIKLLREGKQL- 72
+G+R +APY+ + KGRW G+ + ++F EF T+ KI ++ G+Q+
Sbjct: 62 DGVRHLAPYWACYRTRTKGRWIGRKMVEVFSGEFLSTNRN-YAKIACKMGRIYVNGEQMT 120
Query: 73 EGDPIIKNKDILLTYQHNHEPPVKNWGEPICDEKHIMGIPIVHQDEQLLVINKPNGIPVH 132
+ D +++N D + + H HE P+++ + I ++ + + L V+ KP +PVH
Sbjct: 121 DVDYVMRNGDRVEHWAHRHEHPIRD-----------LPIRVISETDDLFVVEKPPSLPVH 169
Query: 133 PTAYFYKNTLTELLKDSLGYP-VHPCYRLDKITSGLLILAKNPIDANRVQSKIRDRDMKK 191
+ +T+ L+ + G + +RLD+ TSG+L+ AKN ++ ++ + K
Sbjct: 170 TCGQYAIHTVLGQLRVNEGRTGLRVLHRLDRATSGVLLFAKNYETDLEFKTTLKQGEWSK 229
Query: 192 YYLARVKGKFP-ETAVDKSPIYTCDLKIKSEPLSPL-KDAHTEFELMEYDAVTDQSIVLC 249
Y+ +V G FP E V + PI + + + + P KDA + F + D QS+V
Sbjct: 230 EYICKVDGVFPDEEQVCEQPIGPLVISMGIQCVRPDGKDAKSRFRKLWSDGT--QSVVQV 287
Query: 250 KPFTGRTHQIRIHLARQGHPITNDPFYNL--------DNSTYPLRSRFIIETPDWTQLTN 301
TGRTHQIR+H GHPI D YN N+ Y + E T
Sbjct: 288 HIETGRTHQIRVHSQFLGHPIAGDQIYNSAVWGPTKGKNADYQKSFDELCEDVRNTHKCE 347
Query: 302 ERIEKLRKRFEVELDDV---------------WDQLNENQERCPECDEEMPKDPTPESLE 346
EK FE ++ + +Q E E C +C+ E K P +
Sbjct: 348 NWHEKPNPEFEQRMEHLAADTTPITPEAPSLTLEQRPEFDEICQKCNVESKKVP-ENHFQ 406
Query: 347 LYLHAWRYKGLDLEFETDYPYWA 369
LYLH +Y+ F+T+ P WA
Sbjct: 407 LYLHCLKYETKKWSFKTEMPDWA 429
>ECU05g0680 [A] KOG1919 RNA pseudouridylate synthases
Length = 318
Score = 106 bits (265), Expect = 5e-23
Identities = 100/351 (28%), Positives = 145/351 (40%), Gaps = 48/351 (13%)
Query: 20 APYYNARSSFVKGRWFGKSLTQIFIDEFAHTHEEAQLKITE-GFIKLLREGKQLEGDPII 78
A Y+ + VK RW+ K + + + EF + L E G I + G+ ++ I+
Sbjct: 6 AEYFFTYRTNVKERWYRKPIIDVLVSEFRTRTRDYFLSALECGVITV--NGEAVKPTRIL 63
Query: 79 KNKDILLTYQHNHEPPVKNWGEPICDEKHIMGIPIVHQDEQLLVINKPNGIPVHPTAYFY 138
D++ H H+P G ++ ++ +V+NKP GIP HPT +
Sbjct: 64 GMGDVIRHTVHIHDPAHPEIG-------------VIKEEGDYIVVNKPPGIPCHPTGGYR 110
Query: 139 KNTLTELLKDSLGYPVHPCY-RLDKITSGLLILAKNPIDANRVQSKIRDRDMKKYYLARV 197
+ +T+ L G C RLD SG+LILA N + RD KK Y+A+V
Sbjct: 111 EYCVTKAL---FGDEKVACINRLDMPVSGVLILAVR----NHSKCLEAIRDAKKIYVAKV 163
Query: 198 KGKFPETAVDKSPIYTCDLKIKSEPLSPLKDAHTEFELMEYDAVTDQSIVLCKPFTGRTH 257
G FP+ VD C + K T F +EY S+V C+P TGRTH
Sbjct: 164 YGMFPDK-VDVDKRIGCTEGRYRHVNAGGKACLTLFRRLEYR--DGYSLVECRPVTGRTH 220
Query: 258 QIRIHLARQGHPITNDPFYNLDNSTYPLRSRFIIETPDWTQLTNERIEKLRKRFEVELDD 317
QIRIHL G PI ND Y + P P + N I D
Sbjct: 221 QIRIHLQSIGFPIANDIMYGDGEAPPP---------PQNDGVCNAEI------------D 259
Query: 318 VWDQLNENQERCPECDEEMPKDPTPESLELYLHAWRYKGLDLEFETDYPYW 368
+D + + C + + + LHAW+Y +E+E D P W
Sbjct: 260 GFDDKRKYECIVRHCKGRNNRSFITKDHYICLHAWKYTYNGIEYEADLPGW 310
>At3g52260 [A] KOG1919 RNA pseudouridylate synthases
Length = 346
Score = 75.5 bits (184), Expect = 1e-13
Identities = 73/268 (27%), Positives = 125/268 (46%), Gaps = 42/268 (15%)
Query: 44 IDEFAHTHEEAQLKITEGFIKLLREGK-QLEGDPIIKNKDILLTYQHNHEPPVKNWGEPI 102
+ EF T ++ + G+I+ ++ G+ Q++G+ ++K+ + LL W EP
Sbjct: 35 VSEFYFTKYKSSAPLL-GWIQRIQNGQIQIDGE-VVKDPNTLLRSGSKLVYSRLPWKEP- 91
Query: 103 CDEKHIMGIPIVHQDEQLLVINKPNGIPVHPTAYFYKNTLTELLKDSLG----------- 151
D + + ++++D+ L+ +NKP+G+ V P F + T+ L+ G
Sbjct: 92 -DTPY--SLEVLYEDDDLIALNKPSGLQVLPGGLFQQRTVLTQLQWCFGKNDSYIGSRES 148
Query: 152 -YPVHPCYRLDKITSGLLILAKNPIDANRVQSKIRD-----------------RDMKKYY 193
+PV P +RL + TSG+L+ AK + ++ + + R + K Y
Sbjct: 149 PHPV-PVHRLGRGTSGILLCAKTKLAKTKLAAYFAEGTSLVGSGNLDQECGTGRKLSKIY 207
Query: 194 LARVKGKFPET-AVDKSPIYTCDLKIKSEPL---SPL-KDAHTEFELMEYDAVTDQSIVL 248
A G E V K PI ++ L SP K A ++ ++E D + S+V
Sbjct: 208 RALADGIVEEDEVVIKQPIGVVRYPGVAQGLYVASPEGKPAFSKVFVLERDREKNCSLVK 267
Query: 249 CKPFTGRTHQIRIHLARQGHPITNDPFY 276
+ +GR HQIRIHLA GHP+ DP Y
Sbjct: 268 VEIQSGRPHQIRIHLAYMGHPLVGDPLY 295
>Hs20481524 [A] KOG1919 RNA pseudouridylate synthases
Length = 377
Score = 73.2 bits (178), Expect = 6e-13
Identities = 54/178 (30%), Positives = 88/178 (49%), Gaps = 26/178 (14%)
Query: 113 IVHQDEQLLVINKPNGIPVH--PTAYFYKNTLTELLKDSL----GYPVHPCYRLDKITSG 166
I+HQD+ L+VINKP G+PVH P + +L L P+H C+RLDK T+G
Sbjct: 99 ILHQDKNLVVINKPYGLPVHGGPGVQLCITDVLPILAKMLHGHKAEPLHLCHRLDKETTG 158
Query: 167 LLILAKNPIDANRVQSKIRDRD-MKKYYLARVKGKFPETAVDKSPIYTCDLKIKSE---- 221
+++LA + A++VQ R R +KKY+ V P V PI + + + +
Sbjct: 159 VMVLAWDKDMAHQVQELFRTRQVVKKYWAITVHVPMPSAGVVDIPIVEKEAQGQQQHHKM 218
Query: 222 PLSP------------LKDAHTEFELMEYDAVT---DQSIVLCKPFTGRTHQIRIHLA 264
LSP + + + + +Y ++ ++V +P TG HQ+R+HL+
Sbjct: 219 TLSPSYRMDDGKMVKVRRSRNAQVAVTQYQVLSSTLSSALVELQPITGIKHQLRVHLS 276
>Hs14249470 [A] KOG1919 RNA pseudouridylate synthases
Length = 377
Score = 73.2 bits (178), Expect = 6e-13
Identities = 54/178 (30%), Positives = 88/178 (49%), Gaps = 26/178 (14%)
Query: 113 IVHQDEQLLVINKPNGIPVH--PTAYFYKNTLTELLKDSL----GYPVHPCYRLDKITSG 166
I+HQD+ L+VINKP G+PVH P + +L L P+H C+RLDK T+G
Sbjct: 99 ILHQDKNLVVINKPYGLPVHGGPGVQLCITDVLPILAKMLHGHKAEPLHLCHRLDKETTG 158
Query: 167 LLILAKNPIDANRVQSKIRDRD-MKKYYLARVKGKFPETAVDKSPIYTCDLKIKSE---- 221
+++LA + A++VQ R R +KKY+ V P V PI + + + +
Sbjct: 159 VMVLAWDKDMAHQVQELFRTRQVVKKYWAITVHVPMPSAGVVDIPIVEKEAQGQQQHHKM 218
Query: 222 PLSP------------LKDAHTEFELMEYDAVT---DQSIVLCKPFTGRTHQIRIHLA 264
LSP + + + + +Y ++ ++V +P TG HQ+R+HL+
Sbjct: 219 TLSPSYRMDDGKMVKVRRSRNAQVAVTQYQVLSSTLSSALVELQPITGIKHQLRVHLS 276
>Hs17158025 [A] KOG1919 RNA pseudouridylate synthases
Length = 312
Score = 67.4 bits (163), Expect = 3e-11
Identities = 54/191 (28%), Positives = 86/191 (44%), Gaps = 25/191 (13%)
Query: 108 IMGIPIVHQDEQLLVINKPNGIPVHPTAYFYKNTLT----------ELLKDSLGYPVHPC 157
+ + IV++ LV+NK + + A+ + TLT EL Y C
Sbjct: 6 VENLSIVYRSRDFLVVNKHWDVRIDSKAW--RETLTLQKQLRYRFPELADPDTCYGFRFC 63
Query: 158 YRLDKITSGLLILAKNPIDANRVQSKIRDRDMKKYYLARVKGKFPETAVDKSPI------ 211
++LD TSG L +A N A ++R + K YLA ++G E+ V S
Sbjct: 64 HQLDFSTSGALCVALNKAAAGSAYRCFKERRVTKAYLALLRGHIQESRVTISHAIGRNST 123
Query: 212 ----YTCDLKIKSEPLSPLKDAHTEFELMEYDAVTDQSI--VLCKPFTGRTHQIRIHLAR 265
+T ++ +P K + T+ ++E+ + VL KP TGRTHQ+R+H +
Sbjct: 124 EGRAHTMCIEGSQGCENP-KPSLTDLVVLEHGLYAGDPVSKVLLKPLTGRTHQLRVHCSA 182
Query: 266 QGHPITNDPFY 276
GHP+ D Y
Sbjct: 183 LGHPVVGDLTY 193
>At3g19440 [A] KOG1919 RNA pseudouridylate synthases
Length = 477
Score = 52.8 bits (125), Expect = 8e-07
Identities = 57/215 (26%), Positives = 93/215 (42%), Gaps = 34/215 (15%)
Query: 93 PPVKNWGEPICDEKHIMGIPIV-HQDEQLLVINKPNGIPVHPTAYFYKNTLTELLKDSLG 151
PP K DE+ +V ++D ++V+NKP+G+ V + K ++ EL L
Sbjct: 164 PPAKKESFQCSDEERKFVCSLVLYKDPAIIVLNKPHGLAVQGGSGI-KTSIDELAASCLK 222
Query: 152 YPVHPC----YRLDKITSGLLILAKNPIDANRVQSKIRDR--------------DMKKYY 193
+ +RLD+ SGLL+LA+ A + S R++ +K+ Y
Sbjct: 223 FDKSESPRLVHRLDRDCSGLLVLARTQTAATVLHSIFREKTTGASAYGVKKNVKSLKRKY 282
Query: 194 LARVKGKFP-----------ETAVDKSPIYTCDLKIKSEPLSPLKDAHTEFELMEYDAVT 242
+A V G P + VD + E +S + A TE+ ++E +
Sbjct: 283 MALVIGCPPRQRGQISAPLRKVVVDDGKSERITVNDNGELVST-QHAITEYRVIE-SSPH 340
Query: 243 DQSIVLCKPFTGRTHQIRIHLAR-QGHPITNDPFY 276
+ + +P TGR HQ+R+H A G PI D Y
Sbjct: 341 GYTWLELRPLTGRKHQLRVHCAEVLGTPIVGDYKY 375
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.319 0.139 0.424
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,316,931
Number of Sequences: 60738
Number of extensions: 1178029
Number of successful extensions: 2984
Number of sequences better than 1.0e-05: 15
Number of HSP's better than 0.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 2920
Number of HSP's gapped (non-prelim): 20
length of query: 377
length of database: 30,389,216
effective HSP length: 108
effective length of query: 269
effective length of database: 23,829,512
effective search space: 6410138728
effective search space used: 6410138728
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)