ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI3896 good BK KOG2684 Chromatin structure and dynamics Sirtuin 5 and related class III sirtuins (SIR2 family)
r_klactVI3896 good BK KOG2684 Transcription Sirtuin 5 and related class III sirtuins (SIR2 family)
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI3896 1360451 1358442 -670
(670 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YOL068c [BK] KOG2684 Sirtuin 5 and related class III sirtuins (S... 596 e-170
YDL042c [BK] KOG2684 Sirtuin 5 and related class III sirtuins (S... 596 e-170
SPBC16D10.07c [BK] KOG2684 Sirtuin 5 and related class III sirtu... 268 2e-71
7298007 [BK] KOG2684 Sirtuin 5 and related class III sirtuins (S... 236 8e-62
Hs7657575 [BK] KOG2684 Sirtuin 5 and related class III sirtuins ... 227 5e-59
CE06302 [BK] KOG2684 Sirtuin 5 and related class III sirtuins (S... 201 2e-51
SPCC132.02 [BK] KOG2682 NAD-dependent histone deacetylases and c... 162 1e-39
Hs6912660 [BK] KOG2682 NAD-dependent histone deacetylases and cl... 157 5e-38
Hs13775602 [BK] KOG2682 NAD-dependent histone deacetylases and c... 156 1e-37
Hs13775600 [BK] KOG2682 NAD-dependent histone deacetylases and c... 156 1e-37
YPL015c [BK] KOG2682 NAD-dependent histone deacetylases and clas... 132 2e-30
YOR025w [BK] KOG2684 Sirtuin 5 and related class III sirtuins (S... 110 7e-24
ECU03g0460 [BK] KOG2684 Sirtuin 5 and related class III sirtuins... 88 4e-17
SPAC1783.04c [BK] KOG2684 Sirtuin 5 and related class III sirtui... 87 1e-16
Hs6912664 [BK] KOG2684 Sirtuin 5 and related class III sirtuins ... 72 3e-12
Hs13787215 [BK] KOG2684 Sirtuin 5 and related class III sirtuins... 72 4e-12
At5g55760 [BK] KOG1905 Class IV sirtuins (SIR2 family) 70 8e-12
YDR191w [BK] KOG2684 Sirtuin 5 and related class III sirtuins (S... 70 1e-11
Hs7706712 [BK] KOG1905 Class IV sirtuins (SIR2 family) 58 4e-08
7290606 [BK] KOG2683 Sirtuin 4 and related class II sirtuins (SI... 52 2e-06
>YOL068c [BK] KOG2684 Sirtuin 5 and related class III sirtuins (SIR2 family)
Length = 503
Score = 596 bits (1536), Expect = e-170
Identities = 287/455 (63%), Positives = 356/455 (78%), Gaps = 14/455 (3%)
Query: 155 HPIKLERRSVSRKYVFPVISKEDSLNARSYLKQFGSARFLDDYLPEDLNSLYVYHMIKLL 214
+P L + V+ K++FP I+K+D +NAR +LK FL+ +LP ++NS+Y+Y MIKLL
Sbjct: 54 YPCILGKDKVTGKFIFPAITKDDVMNARLFLKDNDLKTFLEYFLPVEVNSIYIYFMIKLL 113
Query: 215 GFQIKDKELMLAIQEVVHNADNDDSLPQKNSSETKNVSDTYTATYPSPSFEDPLEKKHAV 274
GF +KDKEL +A+ N S +++S+E +S + DPLEKKHAV
Sbjct: 114 GFDVKDKELFMALNS------NITSNKERSSAE---LSSIHAKAEDEDELTDPLEKKHAV 164
Query: 275 RLIKDLQKAMNKVLSTRIRLTNFHTIDDFVAKLKTAKKIIVLTGAGISTSLGIPDFRSSE 334
+LIKDLQKA+NKVLSTR+RL NF+TID F A L+ AKKI+VLTGAG+STSLGIPDFRSSE
Sbjct: 165 KLIKDLQKAINKVLSTRLRLPNFNTIDHFTATLRNAKKILVLTGAGVSTSLGIPDFRSSE 224
Query: 335 GFYSKLGDLGLNDPQDVFSLEVFTEDPSVFYNIAHMVLPPENMYSPLHSFIKMIQDKDKL 394
GFYSK+ LGL DPQDVF+L++F +DPSVFYNIAHMVLPPENMYSPLHSFIKM+QDK KL
Sbjct: 225 GFYSKIRHLGLEDPQDVFNLDIFLQDPSVFYNIAHMVLPPENMYSPLHSFIKMLQDKGKL 284
Query: 395 LRNYTQNIDNLESYAGVEPEKMVQCHGSFATASCVTCHWKIQGERIFPNIRNLQLPICPY 454
LRNYTQNIDNLESYAG++P+K+VQCHGSFATASCVTCHW+I GE+IF NIRNL+LP+CPY
Sbjct: 285 LRNYTQNIDNLESYAGIDPDKLVQCHGSFATASCVTCHWQIPGEKIFENIRNLELPLCPY 344
Query: 455 CYSKRLEFFKTKTXXXXXXXXXXXXXXHHGRSVPKSFGVLKPDITFFGEALPSKFHRLIR 514
CY KR ++F + + KS+GVLKPD+TFFGEALPS+FH+ IR
Sbjct: 345 CYQKRKQYFPMSN-----GNNTVQTNINFNSPILKSYGVLKPDMTFFGEALPSRFHKTIR 399
Query: 515 EDVLQCDLLICIGTSLKVAPVSEIVNMIPAHVPQVLINKDPVKHAEFDLSLLGLCDDVAA 574
+D+L+CDLLICIGTSLKVAPVSEIVNM+P+HVPQ+LIN+D V HAEFDL+LLG CDDVA+
Sbjct: 400 KDILECDLLICIGTSLKVAPVSEIVNMVPSHVPQILINRDMVTHAEFDLNLLGFCDDVAS 459
Query: 575 LVAQKCGWDIPHDNWNKLKNKVFDSEEVERGVYKV 609
LVA+KC WDIPH W LK ++ E+++G YK+
Sbjct: 460 LVAKKCHWDIPHKKWQDLKKIDYNCTEIDKGTYKI 494
>YDL042c [BK] KOG2684 Sirtuin 5 and related class III sirtuins (SIR2 family)
Length = 562
Score = 596 bits (1536), Expect = e-170
Identities = 294/467 (62%), Positives = 356/467 (75%), Gaps = 13/467 (2%)
Query: 143 LSDRQYAPQKPEHPIKLERRSVSRKYVFPVISKEDSLNARSYLKQFGSARFLDDYLPEDL 202
+S+ P+ P+ PI + + + + P +K +SLNAR +LK +G+ +FLD YLPEDL
Sbjct: 100 MSNDVLKPETPKGPIIISKNPSNGIFYGPSFTKRESLNARMFLKYYGAHKFLDTYLPEDL 159
Query: 203 NSLYVYHMIKLLGFQIKDKELMLAIQEVVHNADNDDSLPQKNSSETKNVSDTYTATYPSP 262
NSLY+Y++IKLLGF++KD+ L+ I +VH NS E V D +A +
Sbjct: 160 NSLYIYYLIKLLGFEVKDQALIGTINSIVHI----------NSQE--RVQDLGSAISVT- 206
Query: 263 SFEDPLEKKHAVRLIKDLQKAMNKVLSTRIRLTNFHTIDDFVAKLKTAKKIIVLTGAGIS 322
+ EDPL KK VRLIKDLQ+A+NKVL TR+RL+NF TID F+ KL TA+KI+VLTGAG+S
Sbjct: 207 NVEDPLAKKQTVRLIKDLQRAINKVLCTRLRLSNFFTIDHFIQKLHTARKILVLTGAGVS 266
Query: 323 TSLGIPDFRSSEGFYSKLGDLGLNDPQDVFSLEVFTEDPSVFYNIAHMVLPPENMYSPLH 382
TSLGIPDFRSSEGFYSK+ LGL+DPQDVF+ +F DPSVFYNIA+MVLPPE +YSPLH
Sbjct: 267 TSLGIPDFRSSEGFYSKIKHLGLDDPQDVFNYNIFMHDPSVFYNIANMVLPPEKIYSPLH 326
Query: 383 SFIKMIQDKDKLLRNYTQNIDNLESYAGVEPEKMVQCHGSFATASCVTCHWKIQGERIFP 442
SFIKM+Q K KLLRNYTQNIDNLESYAG+ +K+VQCHGSFATA+CVTCHW + GERIF
Sbjct: 327 SFIKMLQMKGKLLRNYTQNIDNLESYAGISTDKLVQCHGSFATATCVTCHWNLPGERIFN 386
Query: 443 NIRNLQLPICPYCYSKRLEFFKTKTXXXXXXXXXXXXXXHHGRSVPKSFGVLKPDITFFG 502
IRNL+LP+CPYCY KR E+F + S+GVLKPDITFFG
Sbjct: 387 KIRNLELPLCPYCYKKRREYFPEGYNNKVGVAASQGSMSERPPYILNSYGVLKPDITFFG 446
Query: 503 EALPSKFHRLIREDVLQCDLLICIGTSLKVAPVSEIVNMIPAHVPQVLINKDPVKHAEFD 562
EALP+KFH+ IRED+L+CDLLICIGTSLKVAPVSEIVNM+P+HVPQVLIN+DPVKHAEFD
Sbjct: 447 EALPNKFHKSIREDILECDLLICIGTSLKVAPVSEIVNMVPSHVPQVLINRDPVKHAEFD 506
Query: 563 LSLLGLCDDVAALVAQKCGWDIPHDNWNKLKNKVFDSEEVERGVYKV 609
LSLLG CDD+AA+VAQKCGW IPH WN LKNK F +E ++GVY V
Sbjct: 507 LSLLGYCDDIAAMVAQKCGWTIPHKKWNDLKNKNFKCQEKDKGVYVV 553
>SPBC16D10.07c [BK] KOG2684 Sirtuin 5 and related class III sirtuins (SIR2 family)
Length = 471
Score = 268 bits (685), Expect = 2e-71
Identities = 134/317 (42%), Positives = 199/317 (62%), Gaps = 3/317 (0%)
Query: 268 LEKKHAVRLIKDLQKAMNKVLSTRIRLTNFHTIDDFVAKLKTAKKIIVLTGAGISTSLGI 327
LE+ + L+ L++ + + ++ RI+L +F+T +D V LK AK ++VL GAGISTSLGI
Sbjct: 110 LEEFEDIDLLPLLKEVLKREVARRIKLPHFNTFEDVVNLLKKAKNVVVLVGAGISTSLGI 169
Query: 328 PDFRSSEGFYSKLGDLGLNDPQDVFSLEVFTEDPSVFYNIAHMVLPPENMYSPLHSFIKM 387
DFRS GFY++L GL++P ++F + F E+P +FY A +LP N YSP H+FI++
Sbjct: 170 LDFRSDNGFYARLARHGLSEPSEMFDIHTFRENPEIFYTFARDLLPETNHYSPSHAFIRL 229
Query: 388 IQDKDKLLRNYTQNIDNLESYAGVEPEKMVQCHGSFATASCVTCHWKIQGERIFPNIRNL 447
++ K+KL +TQNIDNLE G+ K++QCHGSFATA+C+ C K+ G ++ +IRN
Sbjct: 230 LEKKNKLSTLFTQNIDNLEKKTGLSDNKIIQCHGSFATATCIKCKHKVDGSELYEDIRNQ 289
Query: 448 QLPICPYCYSKRLEFFKTKTXXXXXXXXXXXXXXHHGRSVPKSFGVLKPDITFFGEALPS 507
++ C C L+ + + + G++KPDITFFGEALP
Sbjct: 290 RVSYCNECGKPPLKLRRVGQNKKEKHYFSDGDSESSEDDLAQP-GIMKPDITFFGEALPD 348
Query: 508 KFHRLIREDVL-QCDLLICIGTSLKVAPVSEIVNMIPAHVPQVLINKDPVKHAEFDLSLL 566
F + L + DLLICIGTSLKVAPVSE++++IP PQ+ I++ PV+H +FD++ L
Sbjct: 349 SFFNKVGSGELEETDLLICIGTSLKVAPVSELISVIPPTTPQIYISRTPVRHTQFDVNFL 408
Query: 567 G-LCDDVAALVAQKCGW 582
CD V + ++ GW
Sbjct: 409 SPYCDWVIVEICKRAGW 425
>7298007 [BK] KOG2684 Sirtuin 5 and related class III sirtuins (SIR2 family)
Length = 823
Score = 236 bits (602), Expect = 8e-62
Identities = 125/292 (42%), Positives = 178/292 (60%), Gaps = 18/292 (6%)
Query: 291 RIRLTNFHTIDDFVAKLKTAKKIIVLTGAGISTSLGIPDFRSSEGFYSKLGD--LGLNDP 348
R +L + +T DD ++ +K ++KIIVLTGAG+S S GIPDFRS+ G Y++L L DP
Sbjct: 202 RNKLASVNTFDDVISLVKKSQKIIVLTGAGVSVSCGIPDFRSTNGIYARLAHDFPDLPDP 261
Query: 349 QDVFSLEVFTEDPSVFYNIAHMVLPPENMYSPLHSFIKMIQDKDKLLRNYTQNIDNLESY 408
Q +F + F DP FY A + P E SP H FIKM++ K KLLRNYTQNID LE
Sbjct: 262 QAMFDINYFKRDPRPFYKFAREIYPGEFQPSPCHRFIKMLETKGKLLRNYTQNIDTLERV 321
Query: 409 AGVEPEKMVQCHGSFATASCVTCHWKIQGERIFPNIRNLQLPICPYCYSKRLEFFKTKTX 468
AG++ ++++CHGSF+TASC C +K + + +I ++P+CP C + +
Sbjct: 322 AGIQ--RVIECHGSFSTASCTKCRFKCNADALRADIFAQRIPVCPQCQPNKEQSVDASVA 379
Query: 469 XXXXXXXXXXXXXHHGRSVPKSFGVLKPDITFFGEALPSKFHRLIREDVLQCDLLICIGT 528
R + ++ G++KPDI FFGE LP ++H ++ D CDLLI IG+
Sbjct: 380 VTEEEL----------RQLVEN-GIMKPDIVFFGEGLPDEYHTVMATDKDVCDLLIVIGS 428
Query: 529 SLKVAPVSEIVNMIPAHVPQVLINKDPVKHAEFDLSLLGLCDDVAALVAQKC 580
SLKV PV+ I + IPA VPQ+LIN++ + H +FD+ LLG D ++ Q C
Sbjct: 429 SLKVRPVAHIPSSIPATVPQILINREQLHHLKFDVELLG---DSDVIINQIC 477
>Hs7657575 [BK] KOG2684 Sirtuin 5 and related class III sirtuins (SIR2 family)
Length = 747
Score = 227 bits (578), Expect = 5e-59
Identities = 130/333 (39%), Positives = 184/333 (55%), Gaps = 42/333 (12%)
Query: 251 VSDTYTATYPSPSFEDPLEKKHAVRLIKDLQKAMNKVLSTRIRLTNFHTIDDFVAKLKTA 310
+ D T P P +D + + ++ + K R + + +TI+D V L+
Sbjct: 202 LKDLLPETIPPPELDDMTLWQIVINILSEPPK--------RKKRKDINTIEDAVKLLQEC 253
Query: 311 KKIIVLTGAGISTSLGIPDFRSSEGFYSKLG-DL-GLNDPQDVFSLEVFTEDPSVFYNIA 368
KKIIVLTGAG+S S GIPDFRS +G Y++L D L DPQ +F +E F +DP F+ A
Sbjct: 254 KKIIVLTGAGVSVSCGIPDFRSRDGIYARLAVDFPDLPDPQAMFDIEYFRKDPRPFFKFA 313
Query: 369 HMVLPPENMYSPLHSFIKMIQDKDKLLRNYTQNIDNLESYAGVEPEKMVQCHGSFATASC 428
+ P + S H FI + + KLLRNYTQNID LE AG+ ++++QCHGSFATASC
Sbjct: 314 KEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGI--QRIIQCHGSFATASC 371
Query: 429 VTCHWKIQGERIFPNIRNLQLPICPYCYSKRLEFFKTKTXXXXXXXXXXXXXXHHGRSVP 488
+ C +K+ E + +I N +P CP C
Sbjct: 372 LICKYKVDCEAVRGDIFNQVVPRCPRC------------------------------PAD 401
Query: 489 KSFGVLKPDITFFGEALPSKFHRLIREDVLQCDLLICIGTSLKVAPVSEIVNMIPAHVPQ 548
+ ++KP+I FFGE LP +FHR ++ D + DLLI IG+SLKV PV+ I + IP VPQ
Sbjct: 402 EPLAIMKPEIVFFGENLPEQFHRAMKYDKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQ 461
Query: 549 VLINKDPVKHAEFDLSLLGLCDDVAALVAQKCG 581
+LIN++P+ H FD+ LLG CD + + + G
Sbjct: 462 ILINREPLPHLHFDVELLGDCDVIINELCHRLG 494
>CE06302 [BK] KOG2684 Sirtuin 5 and related class III sirtuins (SIR2 family)
Length = 607
Score = 201 bits (512), Expect = 2e-51
Identities = 110/284 (38%), Positives = 160/284 (55%), Gaps = 39/284 (13%)
Query: 291 RIRLTNFHTIDDFVAKLKTAKKIIVLTGAGISTSLGIPDFRSSEGFYSKLGDL--GLNDP 348
R +LTN++++ D V KT K I+VLTGAG+S S GIPDFRS +G Y++L L DP
Sbjct: 126 RQKLTNYNSLADAVELFKTKKHILVLTGAGVSVSCGIPDFRSKDGIYARLRSEFPDLPDP 185
Query: 349 QDVFSLEVFTEDPSVFYNIAHMVLPPENMYSPLHSFIKMIQDKDKLLRNYTQNIDNLESY 408
+F + F E+P+ FYN A + P + + S H FIK ++ +LLRNYTQNID LE
Sbjct: 186 TAMFDIRYFRENPAPFYNFAREIFPGQFVPSVSHRFIKELETSGRLLRNYTQNIDTLEHQ 245
Query: 409 AGVEPEKMVQCHGSFATASCVTCHWKIQGERIFPNIRNLQLPICPYCYSKRLEFFKTKTX 468
G+ +++V+CHGSF+ +C C K G I + +++ C C
Sbjct: 246 TGI--KRVVECHGSFSKCTCTRCGQKYDGNEIREEVLAMRVAHCKRCE------------ 291
Query: 469 XXXXXXXXXXXXXHHGRSVPKSFGVLKPDITFFGEALPSKFHRLIREDVLQCDLLICIGT 528
GV+KP+I FFGE L +FH+ + ED + DL++ IG+
Sbjct: 292 -----------------------GVIKPNIVFFGEDLGREFHQHVTEDKHKVDLIVVIGS 328
Query: 529 SLKVAPVSEIVNMIPAHVPQVLINKDPVKHAEFDLSLLGLCDDV 572
SLKV PV+ I + + +VPQ+LIN++ + H D+ LLG CDD+
Sbjct: 329 SLKVRPVALIPHCVDKNVPQILINRESLPHYNADIELLGNCDDI 372
>SPCC132.02 [BK] KOG2682 NAD-dependent histone deacetylases and class I
sirtuins (SIR2 family)
Length = 332
Score = 162 bits (411), Expect = 1e-39
Identities = 94/276 (34%), Positives = 140/276 (50%), Gaps = 39/276 (14%)
Query: 311 KKIIVLTGAGISTSLGIPDFRSSE-GFYSKLGDLGLNDPQDVFSLEVFTEDPSVFYNIAH 369
KKI V+ GAGIST+ GIPDFRS E G Y+ L L + VF L F ++P FY +AH
Sbjct: 28 KKICVMVGAGISTAAGIPDFRSPETGIYNNLQRFNLPYAEAVFDLSYFRKNPRPFYELAH 87
Query: 370 MVLPPENMYSPLHSFIKMIQDKDKLLRNYTQNIDNLESYAGVEPEKMVQCHGSFATASCV 429
++P + + H FI+++ DK L + YTQNID LE AGV + +++ HGSF + C+
Sbjct: 88 ELMPEKYRPTYTHYFIRLLHDKRLLQKCYTQNIDTLERLAGVPDKALIEAHGSFQYSRCI 147
Query: 430 TCHWKIQGERIFPNIRNLQLPICPYCYSKRLEFFKTKTXXXXXXXXXXXXXXHHGRSVPK 489
C+ + E + I Q+P C C
Sbjct: 148 ECYEMAETEYVRACIMQKQVPKCNSCK--------------------------------- 174
Query: 490 SFGVLKPDITFFGEALPSKFHRLIREDVLQCDLLICIGTSLKVAPVSEIVNMIPAHVPQV 549
G++KP I F+GE LP +F + +D CD+ + IGTSL V P +++ ++P +V
Sbjct: 175 --GLIKPMIVFYGEGLPMRFFEHMEKDTKVCDMALVIGTSLLVHPFADLPEIVPNKCQRV 232
Query: 550 LINKDPV---KHAEFDLSLLGLCDDVAALVAQKCGW 582
LIN++P + D+ +LG CD + + GW
Sbjct: 233 LINREPAGDFGERKKDIMILGDCDSQVRALCKLLGW 268
>Hs6912660 [BK] KOG2682 NAD-dependent histone deacetylases and class I
sirtuins (SIR2 family)
Length = 399
Score = 157 bits (397), Expect = 5e-38
Identities = 90/252 (35%), Positives = 131/252 (51%), Gaps = 37/252 (14%)
Query: 306 KLKTAKKIIVLTGAGISTSLGIPDFRS-SEGFYSKLGDLGLNDPQDVFSLEVFTEDPSVF 364
+ + ++++V+ GAGIST GIPDFRS G YS L L P+ +F L F +P F
Sbjct: 133 RARACQRVVVMVGAGISTPSGIPDFRSPGSGLYSNLQQYDLPYPEAIFELPFFFHNPKPF 192
Query: 365 YNIAHMVLPPENMYSPLHSFIKMIQDKDKLLRNYTQNIDNLESYAGVEPEKMVQCHGSFA 424
+ +A + P + H F++++ DK LLR YTQNID LE +G+ K+V+ HG+FA
Sbjct: 193 FTLAKELYPGNYKPNVTHYFLRLLHDKGLLLRLYTQNIDGLERVSGIPASKLVEAHGTFA 252
Query: 425 TASCVTCHWKIQGERIFPNIRNLQLPICPYCYSKRLEFFKTKTXXXXXXXXXXXXXXHHG 484
+A+C C GE I ++ ++P CP C
Sbjct: 253 SATCTVCQRPFPGEDIRADVMADRVPRCPVC----------------------------- 283
Query: 485 RSVPKSFGVLKPDITFFGEALPSKFHRLIREDVLQCDLLICIGTSLKVAPVSEIVNMIPA 544
GV+KPDI FFGE LP +F L D DLL+ +GTSL+V P + + + +
Sbjct: 284 ------TGVVKPDIVFFGEPLPQRF-LLHVVDFPMADLLLILGTSLEVEPFASLTEAVRS 336
Query: 545 HVPQVLINKDPV 556
VP++LIN+D V
Sbjct: 337 SVPRLLINRDLV 348
>Hs13775602 [BK] KOG2682 NAD-dependent histone deacetylases and class I
sirtuins (SIR2 family)
Length = 352
Score = 156 bits (394), Expect = 1e-37
Identities = 99/300 (33%), Positives = 148/300 (49%), Gaps = 67/300 (22%)
Query: 311 KKIIVLTGAGISTSLGIPDFRS-SEGFYSKLGDLGLNDPQDVFSLEVFTEDPSVFYNIAH 369
+++I L GAGISTS GIPDFRS S G Y L L P+ +F + F + P F+ +A
Sbjct: 40 RRVICLVGAGISTSAGIPDFRSPSTGLYDNLEKYHLPYPEAIFEISYFKKHPEPFFALAK 99
Query: 370 MVLPPENMYSPLHSFIKMIQDKDKLLRNYTQNIDNLESYAGVEPEKMVQCHGSFATASCV 429
+ P + + H F+++++DK LLR YTQNID LE AG+E E +V+ HG+F T+ CV
Sbjct: 100 ELYPGQFKPTICHYFMRLLKDKGLLLRCYTQNIDTLERIAGLEQEDLVEAHGTFYTSHCV 159
Query: 430 TCHWKIQ------GERIFPNIRNLQLPICPYCYSKRLEFFKTKTXXXXXXXXXXXXXXHH 483
+ + + E+IF + P C C S
Sbjct: 160 SASCRHEYPLSWMKEKIFSEV----TPKCEDCQS-------------------------- 189
Query: 484 GRSVPKSFGVLKPDITFFGEALPSKFHRLIREDVLQCDLLICIGTSLKVAPVSEIVNMIP 543
++KPDI FFGE+LP++F ++ D L+ DLL+ +GTSL+V P + +++ P
Sbjct: 190 ---------LVKPDIVFFGESLPARFFSCMQSDFLKVDLLLVMGTSLQVQPFASLISKAP 240
Query: 544 AHVPQVLINKDPV---------------------KHAEFDLSLLGLCDDVAALVAQKCGW 582
P++LINK+ K A D++ LG CD +A+ GW
Sbjct: 241 LSTPRLLINKEKAGQSDPFLGMIMGLGGGMDFDSKKAYRDVAWLGECDQGCLALAELLGW 300
>Hs13775600 [BK] KOG2682 NAD-dependent histone deacetylases and class I
sirtuins (SIR2 family)
Length = 389
Score = 156 bits (394), Expect = 1e-37
Identities = 99/300 (33%), Positives = 148/300 (49%), Gaps = 67/300 (22%)
Query: 311 KKIIVLTGAGISTSLGIPDFRS-SEGFYSKLGDLGLNDPQDVFSLEVFTEDPSVFYNIAH 369
+++I L GAGISTS GIPDFRS S G Y L L P+ +F + F + P F+ +A
Sbjct: 77 RRVICLVGAGISTSAGIPDFRSPSTGLYDNLEKYHLPYPEAIFEISYFKKHPEPFFALAK 136
Query: 370 MVLPPENMYSPLHSFIKMIQDKDKLLRNYTQNIDNLESYAGVEPEKMVQCHGSFATASCV 429
+ P + + H F+++++DK LLR YTQNID LE AG+E E +V+ HG+F T+ CV
Sbjct: 137 ELYPGQFKPTICHYFMRLLKDKGLLLRCYTQNIDTLERIAGLEQEDLVEAHGTFYTSHCV 196
Query: 430 TCHWKIQ------GERIFPNIRNLQLPICPYCYSKRLEFFKTKTXXXXXXXXXXXXXXHH 483
+ + + E+IF + P C C S
Sbjct: 197 SASCRHEYPLSWMKEKIFSEV----TPKCEDCQS-------------------------- 226
Query: 484 GRSVPKSFGVLKPDITFFGEALPSKFHRLIREDVLQCDLLICIGTSLKVAPVSEIVNMIP 543
++KPDI FFGE+LP++F ++ D L+ DLL+ +GTSL+V P + +++ P
Sbjct: 227 ---------LVKPDIVFFGESLPARFFSCMQSDFLKVDLLLVMGTSLQVQPFASLISKAP 277
Query: 544 AHVPQVLINKDPV---------------------KHAEFDLSLLGLCDDVAALVAQKCGW 582
P++LINK+ K A D++ LG CD +A+ GW
Sbjct: 278 LSTPRLLINKEKAGQSDPFLGMIMGLGGGMDFDSKKAYRDVAWLGECDQGCLALAELLGW 337
>YPL015c [BK] KOG2682 NAD-dependent histone deacetylases and class I
sirtuins (SIR2 family)
Length = 357
Score = 132 bits (331), Expect = 2e-30
Identities = 98/290 (33%), Positives = 135/290 (45%), Gaps = 51/290 (17%)
Query: 312 KIIVLTGAGISTSLGIPDFRS-SEGFYSKLGDLGLNDPQDVFSLEVFTEDPSVFYNIAHM 370
K+I + GAGISTS GIPDFRS G Y L L L P+ VF ++ F DP FY +A
Sbjct: 26 KVIFMVGAGISTSCGIPDFRSPGTGLYHNLARLKLPYPEAVFDVDFFQSDPLPFYTLAKE 85
Query: 371 VLPPENMYSPLHSFIKMIQDKDKLLRNYTQNIDNLESYAGVEPEKMVQCHGSFATASCVT 430
+ P S H +K+ QDKD L R YTQNID LE AGV+ + +++ HGSFA C+
Sbjct: 86 LYPGNFRPSKFHYLLKLFQDKDVLKRVYTQNIDTLERQAGVKDDLIIEAHGSFAHCHCIG 145
Query: 431 CHWKIQGERIFPNIRNLQLPICPYCYSKRLEFFKTKTXXXXXXXXXXXXXXHHGRSVPKS 490
C K+ ++F + + + PI +F K
Sbjct: 146 C-GKVYPPQVFKS-KLAEHPI--------KDFVKCDVCGE-------------------- 175
Query: 491 FGVLKPDITFFGEALPSKFHRL-------IREDVL------QCDLLICIGTSLKVAPVSE 537
++KP I FFGE LP F +RE + Q L+I +GTSL V P +
Sbjct: 176 --LVKPAIVFFGEDLPDSFSETWLNDSEWLREKITTSGKHPQQPLVIVVGTSLAVYPFAS 233
Query: 538 IVNMIPAHVPQVLINKDPV-----KHAEFDLSLLGLCDDVAALVAQKCGW 582
+ IP V +VL N + V DL + D+ A + ++ GW
Sbjct: 234 LPEEIPRKVKRVLCNLETVGDFKANKRPTDLIVHQYSDEFAEQLVEELGW 283
>YOR025w [BK] KOG2684 Sirtuin 5 and related class III sirtuins (SIR2 family)
Length = 447
Score = 110 bits (275), Expect = 7e-24
Identities = 90/308 (29%), Positives = 140/308 (45%), Gaps = 62/308 (20%)
Query: 306 KLKTAKKIIVLTGAGISTSLGIPDFRSSEGFYSKLGD-----LGLNDPQDVFSLEVFTED 360
+L +++I LTGAGIS + GIPDFRSS+G Y + + +++F + +F +D
Sbjct: 48 QLSRSRRIACLTGAGISCNAGIPDFRSSDGLYDLVKKDCSQYWSIKSGREMFDISLFRDD 107
Query: 361 --PSVFYNIAHMVLPPENMYSP--LHSFIKMIQDKDKLLRNYTQNIDNLESYAGVEPEK- 415
S+F + + P H FI ++D++KLLR YTQNID LE G+
Sbjct: 108 FKISIFAKFMERLYSNVQLAKPTKTHKFIAHLKDRNKLLRCYTQNIDGLEESIGLTLSNR 167
Query: 416 ---------------MVQCHGSFATASCVTCHWKIQGERIFPN-IRNLQLPICPYC---Y 456
+VQ HG T SC C R + +R +LP+CP C
Sbjct: 168 KLPLTSFSSHWKNLDVVQLHGDLKTLSCTKCFQTFPWSRYWSRCLRRGELPLCPDCEALI 227
Query: 457 SKRLEFFKTKTXXXXXXXXXXXXXXHHGRSVPKSFGVLKPDITFFGEALPS--KFHRLIR 514
+KRL K R++ + G+L+P+I +GE PS + +
Sbjct: 228 NKRLNEGK--------------------RTLGSNVGILRPNIVLYGENHPSCEIITQGLN 267
Query: 515 EDVLQ--CDLLICIGTSLKVAPVSEIVNMIPAHVPQ-----VLINKDPVK----HAEFDL 563
D+++ D LI +GTSLKV V ++V + + +L+NK P+ H D
Sbjct: 268 LDIIKGNPDFLIIMGTSLKVDGVKQLVKKLSKKIHDRGGLIILVNKTPIGESSWHGIIDY 327
Query: 564 SLLGLCDD 571
+ CD+
Sbjct: 328 QIHSDCDN 335
>ECU03g0460 [BK] KOG2684 Sirtuin 5 and related class III sirtuins (SIR2 family)
Length = 425
Score = 88.2 bits (217), Expect = 4e-17
Identities = 89/320 (27%), Positives = 139/320 (42%), Gaps = 45/320 (14%)
Query: 306 KLKTAKKIIVLTGAGISTSLGIPDFRSSEGFYSKL-GDLGLNDPQDVFSLEVFTEDPSVF 364
K+ ++++V+TGAGIS S GIPDFRS G ++ + DLG++ D+F+ + + +
Sbjct: 81 KMFAKRRVVVITGAGISVSSGIPDFRSKSGLFNDIKKDLGVSG-NDLFTYSL-SMSKELR 138
Query: 365 YNIAHMVLPPENMY-----SPLHSFIKMIQDKDKLLRNYTQNIDNLESYAGVEPEK---- 415
+ +NM S H F+ + D + R YTQNID LE AG+ K
Sbjct: 139 KGYLRYISKLKNMVDKAQPSATHEFLSLYSDISRRFRIYTQNIDGLEEKAGLAATKDRST 198
Query: 416 -MVQCHGSFATASCVTCHWKIQ-GERIFPNIRNLQLPICPYCYSKRLEFFKTKTXXXXXX 473
+V HG+ + C+ C +KI+ G+ + +C C +
Sbjct: 199 RLVYLHGNMKSLGCLYCGYKIEFGDAERDAYGRGEEIVCAGCVRRN-------------- 244
Query: 474 XXXXXXXXHHGRSVPK-SFGVLKPDITFFGEALP-SKFHRLIREDVLQCDLLICIGTSLK 531
GR V K GV I + ++ P S F + E CDL I +GTSLK
Sbjct: 245 -------EKRGRDVRKRPVGVFHTTIIHYNQSHPDSSFISKMAEHDNTCDLFIVMGTSLK 297
Query: 532 VAPVSEIV----NMIPAHVPQVLINKD-PVKH--AEFDLSLLGLCDDVAALVAQKCGWDI 584
V V +V + ++L+N D P K FD G CD+ ++ G
Sbjct: 298 VFGVRRLVKYFCRLNSTRGRRILVNLDRPSKEFGELFDFFWNGDCDEFCRVLKDGLGLRS 357
Query: 585 PHDNWNKLK-NKVFDSEEVE 603
D+ +L K DS++ +
Sbjct: 358 VADSVRRLSITKKEDSDKAQ 377
>SPAC1783.04c [BK] KOG2684 Sirtuin 5 and related class III sirtuins (SIR2 family)
Length = 415
Score = 86.7 bits (213), Expect = 1e-16
Identities = 90/295 (30%), Positives = 136/295 (45%), Gaps = 49/295 (16%)
Query: 300 IDDFVAKLKTAKKIIVLTGAGISTSLGIPDFRSSEGFYSKL-GDLGLN-DPQDVFSLEVF 357
+ V+ ++ AK+I+V+TGAGIS GIPDFRSSEG +S L + LN +++F V+
Sbjct: 47 LSPLVSAIRKAKRIVVVTGAGISCDAGIPDFRSSEGLFSSLRAEYKLNCSGKELFDGSVY 106
Query: 358 TEDPSVFYNIAHMVLPPENMYS------PLHSFIKMIQDKDKLLRNYTQNIDNLES-YAG 410
+ SV NI H ++ +M S H F+ + + KLLR YTQNID LE+ G
Sbjct: 107 RDLKSV--NIFHAMIRKLHMLSNNARPTDFHLFLSQLAQESKLLRLYTQNIDFLETRLEG 164
Query: 411 VE-----PEK-----MVQCHGSFATASCVTCHWKIQGERIFPNI--RNLQLPICPYCYSK 458
++ P+ + HG+ SC C + ++ P+I RN + +CP C
Sbjct: 165 LQTCIPLPQSAPWPTTIPLHGTLEVVSCTRCSFL---KKFNPDIFDRN-GVTVCPDC--- 217
Query: 459 RLEFFKTKTXXXXXXXXXXXXXXHHGRSVPKSFGVLKPDITFFGEALP--SKFHRLIRED 516
KT+ RSV + G L+P I + E P + +D
Sbjct: 218 -----KTENEVRRIAGK---------RSVIE--GCLRPRIVLYNEIHPDSESIGSVCSQD 261
Query: 517 V-LQCDLLICIGTSLKVAPVSEIVNMIPAHVPQVLINKDPVKHAEFDLSLLGLCD 570
+ + D LI GTS K+ V I+ + V + N + + E L LCD
Sbjct: 262 LKSRPDCLIVAGTSCKIPGVKRIIKEMSNCVHKQKGNVIWLNYDEPTKDFLNLCD 316
>Hs6912664 [BK] KOG2684 Sirtuin 5 and related class III sirtuins (SIR2 family)
Length = 310
Score = 72.0 bits (175), Expect = 3e-12
Identities = 78/322 (24%), Positives = 124/322 (38%), Gaps = 44/322 (13%)
Query: 275 RLIKDLQKAMNKVLSTRIRLT-----NFHTIDDFVAKLKTAKKIIVLTGAGISTSLGIPD 329
RLI L + STR ++ ++ DF AK I++++GAG+S G+P
Sbjct: 10 RLISQLYCGLKPPASTRNQICLKMARPSSSMADFRKFFAKAKHIVIISGAGVSAESGVPT 69
Query: 330 FRSSEGFYSKLGDLGLNDPQDVFSLEVFTEDPS---VFYNIAHMVL---PPENMYSPLHS 383
FR + G++ K QD+ + F +PS FY+ V+ P + +
Sbjct: 70 FRGAGGYWRKW------QAQDLATPLAFAHNPSRVWEFYHYRREVMGSKEPNAGHRAIAE 123
Query: 384 FIKMIQDKDKLLRNYTQNIDNLESYAGVEPEKMVQCHGSFATASCVTCHWKIQGERIFPN 443
+ + + + TQNID L AG + +++ HGS C +C +
Sbjct: 124 CETRLGKQGRRVVVITQNIDELHRKAGT--KNLLEIHGSLFKTRCTSCGVVAE------- 174
Query: 444 IRNLQLPICPYCYSKRLEFFKTKTXXXXXXXXXXXXXXHHGRSVPKSFGVLKPDITFFGE 503
N + PICP K T+ G G+L+P + +FGE
Sbjct: 175 --NYKSPICPALSGKGAPEPGTQDASIPVEKLPRCEEAGCG-------GLLRPHVVWFGE 225
Query: 504 ALPSKFHRLIREDVLQCDLLICIGTSLKVAPVSEIVNMIPAHVPQVLINKDPVKHAEFDL 563
L + ++ CDL + +GTS V P + PQV PV AEF+
Sbjct: 226 NLDPAILEEVDRELAHCDLCLVVGTSSVVYPAA-------MFAPQVAARGVPV--AEFNT 276
Query: 564 SLLGLCDDVAALVAQKCGWDIP 585
+ CG +P
Sbjct: 277 ETTPATNRFRFHFQGPCGTTLP 298
>Hs13787215 [BK] KOG2684 Sirtuin 5 and related class III sirtuins (SIR2 family)
Length = 299
Score = 71.6 bits (174), Expect = 4e-12
Identities = 71/292 (24%), Positives = 116/292 (39%), Gaps = 36/292 (12%)
Query: 275 RLIKDLQKAMNKVLSTRIRLT-----NFHTIDDFVAKLKTAKKIIVLTGAGISTSLGIPD 329
RLI L + STR ++ ++ DF AK I++++GAG+S G+P
Sbjct: 10 RLISQLYCGLKPPASTRNQICLKMARPSSSMADFRKFFAKAKHIVIISGAGVSAESGVPT 69
Query: 330 FRSSEGFYSKLGDLGLNDPQDVFSLEVFTEDPS---VFYNIAHMVL---PPENMYSPLHS 383
FR + G++ K QD+ + F +PS FY+ V+ P + +
Sbjct: 70 FRGAGGYWRKW------QAQDLATPLAFAHNPSRVWEFYHYRREVMGSKEPNAGHRAIAE 123
Query: 384 FIKMIQDKDKLLRNYTQNIDNLESYAGVEPEKMVQCHGSFATASCVTCHWKIQGERIFPN 443
+ + + + TQNID L AG + +++ HGS C +C +
Sbjct: 124 CETRLGKQGRRVVVITQNIDELHRKAGT--KNLLEIHGSLFKTRCTSCGVVAE------- 174
Query: 444 IRNLQLPICPYCYSKRLEFFKTKTXXXXXXXXXXXXXXHHGRSVPKSFGVLKPDITFFGE 503
N + PICP K T+ G G+L+P + +FGE
Sbjct: 175 --NYKSPICPALSGKGAPEPGTQDASIPVEKLPRCEEAGCG-------GLLRPHVVWFGE 225
Query: 504 ALPSKFHRLIREDVLQCDLLICIGTSLKVAPVSEIVNMIPAH-VPQVLINKD 554
L + ++ CDL + +GTS V P + + A VP N +
Sbjct: 226 NLDPAILEEVDRELAHCDLCLVVGTSSVVYPAAMFAPQVAARGVPVAEFNTE 277
>At5g55760 [BK] KOG1905 Class IV sirtuins (SIR2 family)
Length = 473
Score = 70.5 bits (171), Expect = 8e-12
Identities = 77/290 (26%), Positives = 122/290 (41%), Gaps = 58/290 (20%)
Query: 300 IDDFVAKLKTAKKIIVLTGAGISTSLGIPDFRSSEGFYSKLGDLGLNDPQDVFSLEVFTE 359
I++ ++ +K ++V TGAGISTS GIPDFR +G ++ L G + P+ SL
Sbjct: 34 IEELAKLIQKSKHLVVFTGAGISTSCGIPDFRGPKGIWT-LQREGKDLPKA--SLPFHRA 90
Query: 360 DPSVFYNIAHMVLPPENMYSPLHSFIKMIQDKDKLLRNYTQNIDNLESYAGVEPEKMVQC 419
PS+ HM L L I +QN+D L +G+ EK+ +
Sbjct: 91 MPSM----THMALVELERAGILKFVI-------------SQNVDGLHLRSGIPREKLSEL 133
Query: 420 HG-SFATASCVTCHWKIQGERIFPNIRNLQLPICPYCYSKRLEFFKTKTXXXXXXXXXXX 478
HG SF + +CP C ++ L F+ +T
Sbjct: 134 HGDSF-------------------------MEMCPSCGAEYLRDFEVETIGLKETSRKC- 167
Query: 479 XXXHHGRSVPKSFGVLKPDITFFGEALPSKFHRLIREDVLQCDLLICIGTSLKVAPVSEI 538
SV K LK + + +ALP K + + DL++C+GTSL++ P +
Sbjct: 168 -------SVEKCGAKLKDTVLDWEDALPPKEIDPAEKHCKKADLVLCLGTSLQITPACNL 220
Query: 539 -VNMIPAHVPQVLIN--KDPVKHAEFDLSLLGLCDDVAALVAQKCGWDIP 585
+ + V++N K P K + ++ + GL D V A V + IP
Sbjct: 221 PLKCLKGGGKIVIVNLQKTP-KDKKANVVIHGLVDKVVAGVMESLNMKIP 269
>YDR191w [BK] KOG2684 Sirtuin 5 and related class III sirtuins (SIR2 family)
Length = 370
Score = 69.7 bits (169), Expect = 1e-11
Identities = 86/325 (26%), Positives = 134/325 (40%), Gaps = 58/325 (17%)
Query: 289 STRIRLTNFHTID---DFVA-KLKTAKKIIVLTGAGISTSLGIPDFRSSEGFYSKLGDLG 344
ST + + H +D F++ L +K+++V++GAGIS + GIPDFRSSEG +S +
Sbjct: 67 STHLSKSQRHHMDRDAGFISYALNYSKRMVVVSGAGISVAAGIPDFRSSEGIFSTVNG-- 124
Query: 345 LNDPQDVFSLEVFTEDPSVFYNIAHMV-----LPPENMYSPLHSFIKMIQDKDKLLRNYT 399
+D+F D S+ ++ L + H + +LLR YT
Sbjct: 125 -GSGKDLFDYNRVYGDESMSLKFNQLMVSLFRLSKNCQPTKFHEMLNEFARDGRLLRLYT 183
Query: 400 QNIDNLESYAG--------VEP-EKMVQCHGSFATASCVTC-HWKIQGERIFP-----NI 444
QNID L++ +P VQ HGS C C + K +F +
Sbjct: 184 QNIDGLDTQLPHLSTNVPLAKPIPSTVQLHGSIKHMECNKCLNIKPFDPELFKCDDKFDS 243
Query: 445 RNLQLPICPYCYSKRLEFFKTKTXXXXXXXXXXXXXXHHGRSVPK--SFGVLKPDITFFG 502
R +P CP C E ++T G+ P+ + + P+ F G
Sbjct: 244 RTEIIPSCPQC-----EEYETVRKMAGLRSTGV------GKLRPRVILYNEVHPEGDFIG 292
Query: 503 EALPSKFHRLIREDVLQCDLLICIGTSLKVAPVSEIVNMIPAHVPQ-----VLIN----- 552
E + + I D LI +GTSLK+ V I A V + +N
Sbjct: 293 EIANNDLKKRI-------DCLIIVGTSLKIPGVKNICRQFAAKVHANRGIVLYLNTSMPP 345
Query: 553 KDPVKHAEF-DLSLLGLCDDVAALV 576
K+ + +F DL +LG C V +L+
Sbjct: 346 KNVLDSLKFVDLVVLGDCQHVTSLL 370
>Hs7706712 [BK] KOG1905 Class IV sirtuins (SIR2 family)
Length = 400
Score = 58.2 bits (139), Expect = 4e-08
Identities = 66/300 (22%), Positives = 121/300 (40%), Gaps = 62/300 (20%)
Query: 300 IDDFVAKLKTAKKIIVLTGAGISTSLGIPDFRSSEGFYSKLGDLGLNDPQDVFSLEVFTE 359
+ + + ++ AK ++V TGAGIST+ IPD+R G ++ L + V + ++
Sbjct: 89 VRELASAVRNAKYLVVYTGAGISTAASIPDYRGPNGVWTLL-----QKGRSVSAADLSEA 143
Query: 360 DPSVFYNIAHMVLPPENMYSPLHSFIKMIQDKDKLLRNYTQNIDNLESYAGVEPEKMVQC 419
+P++ H I + ++ + +QN D L +G+ + +
Sbjct: 144 EPTL-----------------THMSITRLHEQKLVQHVVSQNCDGLHLRSGLPRTAISEL 186
Query: 420 HGSFATASCVTCHWKIQGERIFPNIRNLQLPICPYCYSKRLEFFKTKTXXXXXXXXXXXX 479
HG+ C +C + R+F ++R + +T
Sbjct: 187 HGNMYIEVCTSCVPNREYVRVFD-------------VTERTALHRHQT------------ 221
Query: 480 XXHHGRSVPKSFGVLKPDITFFGE----ALPSKFHRLIREDVLQCDLLICIGTSLKVA-- 533
GR+ K L+ I FGE P + E + D ++C+G+SLKV
Sbjct: 222 ----GRTCHKCGTQLRDTIVHFGERGTLGQPLNWEAAT-EAASRADTILCLGSSLKVLKK 276
Query: 534 -PVSEIVNMIPAHVPQV-LINKDPVKHAEFD-LSLLGLCDDVAALVAQKCGWDIP-HDNW 589
P + P+ P++ ++N ++ L L G CDDV L+ + G +IP + W
Sbjct: 277 YPRLWCMTKPPSRRPKLYIVNLQWTPKDDWAALKLHGKCDDVMRLLMAELGLEIPAYSRW 336
>7290606 [BK] KOG2683 Sirtuin 4 and related class II sirtuins (SIR2 family)
Length = 204
Score = 52.4 bits (124), Expect = 2e-06
Identities = 41/140 (29%), Positives = 68/140 (48%), Gaps = 14/140 (10%)
Query: 300 IDDFVAKLKTAKKIIVLTGAGISTSLGIPDFRS-SEGFYSKLGDLGLNDPQDVFSLEVFT 358
++DF L + ++VLTGAGIST GIPD+RS G Y++ + + V S V
Sbjct: 38 LEDF---LLSKPNVLVLTGAGISTESGIPDYRSEGVGLYARSNHKPVQHMEFVKSSAVRK 94
Query: 359 EDPSVFYNIAHMVLPPE---NMYSPLHSFIKMIQDKDKLLRNYTQNIDNLESYAGVEPEK 415
Y + V P+ + H + + ++++ TQN+D L + AG
Sbjct: 95 R-----YWARNFVGWPKFSATQPNATHHALARFEREERVQAVVTQNVDRLHTKAG--SRN 147
Query: 416 MVQCHGSFATASCVTCHWKI 435
+V+ HGS C++C ++I
Sbjct: 148 VVEVHGSGYVVKCLSCEYRI 167
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.317 0.134 0.390
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,957,733
Number of Sequences: 60738
Number of extensions: 1347341
Number of successful extensions: 3790
Number of sequences better than 1.0e-05: 20
Number of HSP's better than 0.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 3732
Number of HSP's gapped (non-prelim): 34
length of query: 670
length of database: 30,389,216
effective HSP length: 113
effective length of query: 557
effective length of database: 23,525,822
effective search space: 13103882854
effective search space used: 13103882854
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)