ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI3976 good J KOG0436 Translation, ribosomal structure and biogenesis Methionyl-tRNA synthetase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI3976 1387875 1386172 -568
(568 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YGR171c [J] KOG0436 Methionyl-tRNA synthetase 576 e-164
Hs14732427 [J] KOG0436 Methionyl-tRNA synthetase 331 2e-90
SPAC27E2.06c [J] KOG0436 Methionyl-tRNA synthetase 320 5e-87
CE25710 [J] KOG0436 Methionyl-tRNA synthetase 253 5e-67
At3g55400 [J] KOG0436 Methionyl-tRNA synthetase 249 8e-66
7299860 [J] KOG0436 Methionyl-tRNA synthetase 247 3e-65
At4g13780_1 [J] KOG1247 Methionyl-tRNA synthetase 100 5e-21
Hs14043022_2 [J] KOG1247 Methionyl-tRNA synthetase 92 2e-18
ECU11g0890 [J] KOG1247 Methionyl-tRNA synthetase 88 4e-17
SPBC17A3.04c [J] KOG1247 Methionyl-tRNA synthetase 85 3e-16
CE06007_1 [J] KOG1247 Methionyl-tRNA synthetase 79 2e-14
>YGR171c [J] KOG0436 Methionyl-tRNA synthetase
Length = 575
Score = 576 bits (1484), Expect = e-164
Identities = 287/568 (50%), Positives = 372/568 (64%), Gaps = 26/568 (4%)
Query: 13 HITTPIFYPNAKPHLGHLYSSLLCDVQNRWKKLAGQDTCFTTGVDEHGLKIQLAAQQKGY 72
H+TTPIFYPNAKPHLGHLYSSLL DV +RW+ G + FTTG DEHGLKIQ A++ G+
Sbjct: 16 HVTTPIFYPNAKPHLGHLYSSLLSDVYHRWQLFKGNLSFFTTGTDEHGLKIQCASESNGF 75
Query: 73 SNPKAFVDELCEHFVHLDKDANIKFTRFIRTTDPDHVNNVKKLWNLCYNNGYIYKGEHKG 132
PK FVD+L FV LDK I +TRFIRTTDPDH+ NV KLW LC NGYIY GEHKG
Sbjct: 76 DQPKKFVDKLYPEFVQLDKIYGINYTRFIRTTDPDHIENVMKLWELCLKNGYIYMGEHKG 135
Query: 133 WYSVSDETFYPDTKILKLTIDGPPIPYDGSFDP--DAKYINSESRNEVTYQSELNYFFKL 190
WYS+SDETFYP++K++K DP D KY+N+ES+NEV YQSE NYFF+L
Sbjct: 136 WYSISDETFYPESKVIK--------------DPKNDGKYLNTESKNEVVYQSETNYFFRL 181
Query: 191 SAFQEPLIKLLRENPTFIYPPLRHSQILRELES-NELRDISVSRPATRLQWGIPVPEDES 249
S F + ++ +R+NP FI+P + QIL+ELE+ L D+S+SRP+ RL+WGIP P D S
Sbjct: 182 SLFNKKIVDHIRKNPDFIFPASKRDQILKELETGGTLPDLSISRPSARLKWGIPTPNDPS 241
Query: 250 QKVYVWFDALCNYLTSIGGIDAIRNDVDSTQVLH-------NNRSFIEKPKEWWENTEHV 302
QKVYVWFDALCNYL+SIGGI +I ++ H + I PKE NT HV
Sbjct: 242 QKVYVWFDALCNYLSSIGGIPSILSNATEVVSRHYSDKSNVKGQLLIPYPKEVQRNTIHV 301
Query: 303 IGKDIIKFHTVYWXXXXXXXXXXXXNRVVVHGHWLSGGVKMSKSLGNVVDPIQIISYYGA 362
IGKDI KFHTVYW ++VVHGHWL G+KMSKSLGNVVDPI + YYGA
Sbjct: 302 IGKDIAKFHTVYWPSFLLAAGLPLPRQIVVHGHWLCNGMKMSKSLGNVVDPIDMARYYGA 361
Query: 363 DTTRWYLLENSNIESDGNFIEKNLWETRELLCSKLGNLINRCGGKKFSLASGVELFSGKP 422
D RW+LLENS +E DG+F E L+ETRELL SK GNLINRC G KF++ V FS K
Sbjct: 362 DIVRWFLLENSKLEEDGDFQEAKLYETRELLVSKWGNLINRCCGSKFNIERAVMKFSDKA 421
Query: 423 IEELSSVFPKES--QAEFTALLKSLDNCTESVNNCFQQYDITGAQKILWNIINEANSFIQ 480
+ +F E L K L+ E + + + +W+IIN+AN+ +Q
Sbjct: 422 NFQFQEIFQNEPIVSERIENLAKLLNKSQEVFDEKIAIFQYPQLLRHVWSIINDANTLVQ 481
Query: 481 STEPWSKKGLEKDLIVYSAMEAARISLIFSQPIIPNIAERLLNRLDVSSDRRTLXXXXXX 540
+++PW ++ ++D I++ AME +RI I Q IIP++++ L+R+DVS ++RT+
Sbjct: 482 NSKPWERELDQQDNIIFLAMETSRILSILCQSIIPSLSQSFLDRIDVSKEKRTINYARLG 541
Query: 541 XXXXXXMTTNQRHKEVPIQRVPFRLHNE 568
+N++ +EVP++++PFRL E
Sbjct: 542 SDKTYGKQSNKKGREVPLKKIPFRLQEE 569
>Hs14732427 [J] KOG0436 Methionyl-tRNA synthetase
Length = 593
Score = 331 bits (848), Expect = 2e-90
Identities = 204/542 (37%), Positives = 287/542 (52%), Gaps = 59/542 (10%)
Query: 13 HITTPIFYPNAKPHLGHLYSSLLCDVQNRWKKLAGQDTC---FTTGVDEHGLKIQLAAQQ 69
+ TTPIFY NA PH+GHLYS+LL D R ++L G T F+TG DEHGLKIQ AA
Sbjct: 46 YFTTPIFYVNAAPHIGHLYSALLADALCRHRRLRGPSTAATRFSTGTDEHGLKIQQAAAT 105
Query: 70 KGYSNPKAFVDELCEHFVHLDKDANIKFTRFIRTTDPDHVNNVKKLWNLCYNNGYIYKGE 129
G + P D + E F L ++A I T FIRTT+ H V+ W + + G +YKG
Sbjct: 106 AGLA-PTELCDRVSEQFQQLFQEAGISCTDFIRTTEARHRVAVQHFWGVLKSRGLLYKGV 164
Query: 130 HKGWYSVSDETFYPDTKILKLTIDGPPIPYDGSFDPDAKYINSESRNEVTYQSELNYFFK 189
++GWY SDE F P+ K+ + P P SF ++ ES + V++ E NY F+
Sbjct: 165 YEGWYCASDECFLPEAKVTQ-----QPGPSGDSFP-----VSLESGHPVSWTKEENYIFR 214
Query: 190 LSAFQEPLIKLLRENPTFIYPPLRHSQILRELESNELRDISVSRPATRLQWGIPVPEDES 249
LS F++PL + LR NP I P H +L+ L+ EL D+SVSR ++ L WGIPVP D+S
Sbjct: 215 LSQFRKPLQRWLRGNPQAITPEPFHHVVLQWLDE-ELPDLSVSRRSSHLHWGIPVPGDDS 273
Query: 250 QKVYVWFDALCNYLTSIGGIDAIRNDVDSTQVLHNNRSFIEKPKEWWENTEHVIGKDIIK 309
Q +YVW DAL NYLT IG + N F K WW T H+IGKDI+K
Sbjct: 274 QTIYVWLDALVNYLTVIG---------------YPNAEF----KSWWPATSHIIGKDILK 314
Query: 310 FHTVYWXXXXXXXXXXXXNRVVVHGHWLSGGVKMSKSLGNVVDPIQIISYYGADTTRWYL 369
FH +YW R+ VH HW G KMSKSLGNVVDP ++ Y D R++L
Sbjct: 315 FHAIYWPAFLLGAGMSPPQRICVHSHWTVCGQKMSKSLGNVVDPRTCLNRYTVDGFRYFL 374
Query: 370 LENSNIESDGNFI-EKNLWETRELLCSKLGNLINRCGGKKFSLASGVELFSGKPIEELSS 428
L D ++ EK + L LG L+NRC K+ + + F ++
Sbjct: 375 LRQGVPNWDCDYYDEKVVKLLNSELADALGGLLNRCTAKRINPSETYPAF-------CTT 427
Query: 429 VFPKE---------SQAEFTALLKSLDNCTESVNNCFQQYDITGAQKILWNIINEANSFI 479
FP E +QAE AL+ ++ + V + + + I A + + + + + N F+
Sbjct: 428 CFPSEPGLVGPSVRAQAEDYALVSAVATLPKQVADHYDNFRIYKALEAVSSCVRQTNGFV 487
Query: 480 QSTEPWSKKGLEKDL-------IVYSAMEAARISLIFSQPIIPNIAERLLNRLDVSSDRR 532
Q PW K E + +++ A+E R+ QP+ P++A++LL+RL VS+ R
Sbjct: 488 QRHAPW-KLNWESPVDAPWLGTVLHVALECLRVFGTLLQPVTPSLADKLLSRLGVSASER 546
Query: 533 TL 534
+L
Sbjct: 547 SL 548
>SPAC27E2.06c [J] KOG0436 Methionyl-tRNA synthetase
Length = 539
Score = 320 bits (819), Expect = 5e-87
Identities = 198/535 (37%), Positives = 280/535 (52%), Gaps = 56/535 (10%)
Query: 12 FHITTPIFYPNAKPHLGHLYSSLLCDVQNRWKKLAGQDTCFT-TGVDEHGLKIQLAAQQK 70
+ +TTPIFY NA PHLGHLYS +L D R++ L + + TG DEHGLK+Q AQ +
Sbjct: 21 YFLTTPIFYVNAAPHLGHLYSLVLTDAIARFQNLKPDVSVISSTGTDEHGLKVQTVAQTE 80
Query: 71 GYSNPKAFVDELCEHFVHLDKDANIKFTRFIRTTDPDHVNNVKKLWNLCYNNGYIYKGEH 130
G S P D + F L AN KFT FIRTT+P H +V++ W G I H
Sbjct: 81 GVS-PLQLCDRNSKRFADLAVAANTKFTHFIRTTNPKHQASVQEFWKTIQKAGMISFERH 139
Query: 131 KGWYSVSDETFYPDTKILKLTIDGPPIPYDGSFDPDAKY---INSESRNEVTYQSELNYF 187
+GWY VSDETFYP++ I K+ DP K ++ E+ EV + SE+NY
Sbjct: 140 EGWYCVSDETFYPESAIQKVV------------DPATKQEKRVSMETGKEVQWSSEMNYH 187
Query: 188 FKLSAFQEPLIKLLRENPTFIYPPLRHSQILRELESNELRDISVSRPATRLQWGIPVPED 247
F LS FQ LI+ +NP F+ P + H+Q+L EL++ + D+S+SRP RL WGIPVP +
Sbjct: 188 FLLSKFQSRLIEHYNKNPNFVQPSIFHTQVLEELKTG-ISDLSISRPKQRLSWGIPVPGN 246
Query: 248 ESQKVYVWFDALCNYLTSIGGIDAIRNDVDSTQVLHNNRSFIEKPKEWWENTEHVIGKDI 307
Q +YVW DAL NY++ IG N +S + W HVIGKDI
Sbjct: 247 SQQTIYVWLDALINYISVIG------------YPWLNEKSSLSAG---WPANMHVIGKDI 291
Query: 308 IKFHTVYWXXXXXXXXXXXXNRVVVHGHWLSGGVKMSKSLGNVVDPIQIISYYGADTTRW 367
I+FH +YW +++VH HW VKMSKSLGNVVDP +I YG DT R+
Sbjct: 292 IRFHCIYWPAFLMAAGLPLPEKILVHSHWTMNKVKMSKSLGNVVDPFWLIEKYGVDTIRY 351
Query: 368 YLLENSNIESDGNF-IEKNLWETRELLCSKLGNLINRCGGKKFSLASGVELFSGKPIEEL 426
YLL+ + SD NF IE+ + L LG L++R KK +++ ++
Sbjct: 352 YLLKRGRLTSDSNFDIEELEKDEEHDLRRSLGVLLSRLQSKKLFISNEIQ---------- 401
Query: 427 SSVFPKESQAEFTALLKSLDN----CTESVN-NCFQQYDITGAQKILWNIINEANSFIQS 481
K+ E+ ++ L C +S++ C Y++ ++ +++ Q
Sbjct: 402 KQWHKKDDFTEYEDIVHELIELPVVCAQSIDGGCV--YEVI---NLVQSVLRRVTKLFQL 456
Query: 482 TEPW--SKKGLEKDLIVYSAMEAARISLIFSQPIIPNIAERLLNRLDVSSDRRTL 534
EPW S EK + + RIS I QPI+P + LL++L + ++R+L
Sbjct: 457 KEPWKLSDDSQEKIDTLMLVAHSLRISGILLQPIMPTKSTELLDQLGIPKNQRSL 511
>CE25710 [J] KOG0436 Methionyl-tRNA synthetase
Length = 622
Score = 253 bits (646), Expect = 5e-67
Identities = 146/392 (37%), Positives = 205/392 (52%), Gaps = 37/392 (9%)
Query: 22 NAKPHLGHLYSSLLCDVQNRWKKLA--GQDTCFTTGVDEHGLKIQLAAQQKGYSNPKAFV 79
+ +PH+GH Y+++LCDV +RW +L G F+ G DEHG KI AA S PK F
Sbjct: 196 STEPHIGHAYTAVLCDVAHRWNRLKHPGAQAQFSIGTDEHGSKIFQAALA-AKSTPKQFC 254
Query: 80 DELCEHFVHLDKDANIKFTRFIRTTDPDHVNNVKKLWNLCYNNGYIYKGEHKGWYSVSDE 139
D + F L D + T FIRTTDP H+ V+ W +NGYIYK + G+YS++DE
Sbjct: 255 DRVSSKFSDLFTDLELSHTNFIRTTDPAHLEAVQHFWMKIQDNGYIYKSTYSGYYSITDE 314
Query: 140 TFYPDTKILKLTIDGPPIPYDGSFDPDAKYINSESRNEVTYQSELNYFFKLSAFQEPLIK 199
F P+ ++K ++G K + V + E NY F+LS F+E + +
Sbjct: 315 CFIPEEDVVKKIVEGGA----------EKLTLKSNGTPVEWIEEENYMFRLSEFREKVAE 364
Query: 200 LLRENPTFIYPPLRHSQILRELESNELRDISVSRPATRLQWGIPVPEDESQKVYVWFDAL 259
+ ++P S L LE +E D+S+SR +RL WGIPVP D +Q +YVW DAL
Sbjct: 365 WINRENIVVHPSKYKSLALTSLEMSE--DLSISRSRSRLSWGIPVPNDPTQTIYVWLDAL 422
Query: 260 CNYLTSIGGIDAIRNDVDSTQVLHNNRSFIEKPKEWWENTEHVIGKDIIKFHTVYWXXXX 319
NYLT G +A + W T VIGKDI KFH YW
Sbjct: 423 VNYLTVTGFPNA---------------------QSVWPPTCQVIGKDITKFHLYYWPAFL 461
Query: 320 XXXXXXXXNRVVVHGHWLSGGVKMSKSLGNVVDPIQIISYYGADTTRWYLLENSNIESDG 379
+V +HGHWL VKMSKSLGNVV+P + I+ + A+ R++LL++ N D
Sbjct: 462 MAAGLSLPQKVFIHGHWLIDNVKMSKSLGNVVNPSEAITKFTAEGLRYFLLKHGNPSYDC 521
Query: 380 NFIEKNLWET-RELLCSKLGNLINRCGGKKFS 410
+F + +T L + +GNL+NR +K +
Sbjct: 522 SFNWNSCLQTINSDLVNNVGNLLNRSTVEKIN 553
>At3g55400 [J] KOG0436 Methionyl-tRNA synthetase
Length = 616
Score = 249 bits (636), Expect = 8e-66
Identities = 158/529 (29%), Positives = 260/529 (48%), Gaps = 58/529 (10%)
Query: 12 FHITTPIFYPNAKPHLGHLYSSLLCDVQNRWKKLAGQDTCFTTGVDEHGLKIQLAAQQKG 71
F +TTP++Y NA PH+G Y+++ D R+++L G+ F TG DEHG KI +A G
Sbjct: 71 FVLTTPLYYVNAPPHMGSAYTTIAADSIARFQRLLGKKVIFITGTDEHGEKIATSAAANG 130
Query: 72 YSNPKAFVDELCEHFVHLDKDANIKFTRFIRTTDPDHVNNVKKLWNLCYNNGYIYKGEHK 131
NP D + + + L KD +I + +FIRTTDP H VK+ + + NG IY+ +++
Sbjct: 131 -RNPPEHCDLISQSYRTLWKDLDIAYDKFIRTTDPKHEAIVKEFYARVFANGDIYRADYE 189
Query: 132 GWYSVSDETFYPDTKILKLTIDGPPIPYDGSFDPDAKYINSESRNEVTYQSELNYFFKLS 191
G Y V+ E + + ++L+ P+ + + E NYFF LS
Sbjct: 190 GLYCVNCEEYKDEKELLENNC--CPV----------------HQMPCVARKEDNYFFALS 231
Query: 192 AFQEPLIKLLRENPTFIYPPLRHSQILRELESNELRDISVSRPATRLQWGIPVPEDESQK 251
+Q+PL +L +NP F+ P R +++ ++S LRD S+SR + WGIPVP+D+ Q
Sbjct: 232 KYQKPLEDILAQNPRFVQPSYRLNEVQSWIKSG-LRDFSISR--ALVDWGIPVPDDDKQT 288
Query: 252 VYVWFDALCNYLTSIGGIDAIRNDVDSTQVLHNNRSFIEKPKEWWENTEHVIGKDIIKFH 311
+YVWFDAL Y++++ + + Q L SF W + H+IGKDI++FH
Sbjct: 289 IYVWFDALLGYISAL-------TEDNKQQNLETAVSF------GWPASLHLIGKDILRFH 335
Query: 312 TVYWXXXXXXXXXXXXNRVVVHGHWLSGGVKMSKSLGNVVDPIQIISYYGADTTRWYLLE 371
VYW V HG G+KM KSLGN ++P +++ +G D R++ L
Sbjct: 336 AVYWPAMLMSAGLELPKMVFGHGFLTKDGMKMGKSLGNTLEPFELVQKFGPDAVRYFFLR 395
Query: 372 NSNIESDGNFIEKNLWE-TRELLCSKLGNLINRCGGKKFSLASGVELFSGKPIEELSSVF 430
+DG++ E + L + +GNL+NR G K E + V
Sbjct: 396 EVEFGNDGDYSEDRFIKIVNAHLANTIGNLLNRTLGLL------------KKNCESTLVV 443
Query: 431 PKESQAEFTALLKSLDNCTESVNNCFQQYDITGAQKILWNIINEANSFIQSTEPW----- 485
AE L +++ E ++ ++ A + + I N N+++ PW
Sbjct: 444 DSTVAAEGVPLKDTVEKLVEKARTNYENLSLSSACEAVLEIGNAGNTYMDQRAPWFLFKQ 503
Query: 486 ---SKKGLEKDLIVYSAMEAARISLIFSQPIIPNIAERLLNRLDVSSDR 531
S + KDL++ +E R+ + P+ P ++ R+ ++L + D+
Sbjct: 504 GGVSAEEAAKDLVI--ILEVMRVIAVALSPVAPCLSLRIYSQLGYTEDQ 550
>7299860 [J] KOG0436 Methionyl-tRNA synthetase
Length = 356
Score = 247 bits (631), Expect = 3e-65
Identities = 141/373 (37%), Positives = 195/373 (51%), Gaps = 37/373 (9%)
Query: 10 SKFHITTPIFYPNAKPHLGHLYSSLLCDVQNRWKKLA--GQDTCFTTGVDEHGLKIQLAA 67
S ++TTPIFY NA PH+GHLYS+++ D R+++L QD TG DEHG KIQ AA
Sbjct: 18 SSHYVTTPIFYVNAAPHIGHLYSAVIADAHCRYQRLRYPEQDVRLCTGTDEHGTKIQQAA 77
Query: 68 QQKGYSNPKAFVDELCEHFVHLDKDANIKFTRFIRTTDPDHVNNVKKLWNLCYNNGYIYK 127
G K + D++ + + + + A+I+ FIRTT+ H V W + G+IY
Sbjct: 78 SLHGVPVAK-YCDDISQRYREVFRSASIQQDDFIRTTEDRHKRAVANFWRTLHTRGHIYS 136
Query: 128 GEHKGWYSVSDETFYPDTKILKLTIDGPPIPYDGSFDPDAKYINSESRNEVTYQSELNYF 187
+ GWY VSDETF D++ L +D + + ES + V + E NY
Sbjct: 137 AAYSGWYCVSDETFLTDSQ---LRLD----------EATGTRYSLESGHPVEWTEETNYM 183
Query: 188 FKLSAFQEPLIKLLRENPTFIYPPLRHSQILRELESNELRDISVSRPATRLQWGIPVPED 247
F+LS FQ+ + ++ P + +IL + S L D+SVSRP+ R+ W IPVP+D
Sbjct: 184 FRLSQFQDDVRHWVKTEARV--RPAKFEKILLDTLSEPLPDVSVSRPSNRVHWAIPVPDD 241
Query: 248 ESQKVYVWFDALCNYLTSIGGIDAIRNDVDSTQVLHNNRSFIEKPKEWWENTEHVIGKDI 307
+SQ VYVW DAL NYL+S+G D EK W + VIGKDI
Sbjct: 242 DSQTVYVWLDALVNYLSSVGYPD-------------------EKFSAHWPPAQQVIGKDI 282
Query: 308 IKFHTVYWXXXXXXXXXXXXNRVVVHGHWLSGGVKMSKSLGNVVDPIQIISYYGADTTRW 367
+KFH +YW ++ VH HW G KMSKS NVVDP+Q Y + R+
Sbjct: 283 LKFHGIYWTAFLLAAGLEPPGQLYVHSHWTVDGQKMSKSKHNVVDPLQAAQQYTMEGLRY 342
Query: 368 YLLENSNIESDGN 380
+LL SDG+
Sbjct: 343 FLLREGVAHSDGS 355
>At4g13780_1 [J] KOG1247 Methionyl-tRNA synthetase
Length = 631
Score = 100 bits (250), Expect = 5e-21
Identities = 129/563 (22%), Positives = 228/563 (39%), Gaps = 100/563 (17%)
Query: 14 ITTPIFYPNAKPHLGHLYSSLL-CDVQNRWKKLAGQDTCFTTGVDEHGLKIQLAAQQKGY 72
IT+ + Y N PHLG++ +L DV R+ +L G + + G DE+G + A ++
Sbjct: 21 ITSALPYVNNVPHLGNIIGCVLSADVYARYCRLRGYNAIYICGTDEYGTATETKALEEN- 79
Query: 73 SNPKAFVDELCEHFVHLDKDA----NIKFTRFIRTTDPDHVNNVKKLWNLCYNNGYIYKG 128
PK E+C+ + + K+ I F +F RT+ P+ + ++N ++N ++ +
Sbjct: 80 CTPK----EICDKYHAIHKEVYDWFGISFDKFGRTSTPEQTEVCQAIFNKLWDNKWLSEN 135
Query: 129 EHKGWYSVSDETFYPDTKILKLTIDGPPIPYDGSFDPDAKYINSESRNEVTYQSELNYFF 188
+ Y + + F D ++G P++G A+ E ++ +EL
Sbjct: 136 TMQQLYCDTCKKFLADR-----LVEG-SCPFEGCNYDSARGDQCEKCGKLLNPTEL---- 185
Query: 189 KLSAFQEPLIKLLRENP-------TFIYPPLRHSQILRELESNE---------------- 225
++P K+ + P FI PL ++ ++
Sbjct: 186 -----KDPKCKVCQNTPRIRDTDHLFIELPLLKDRLEAYIKKTSVTGSWSQNAIQTTNAW 240
Query: 226 LRDISVSRPATR-LQWGIPVPED--ESQKVYVWFDALCNYLTSIGGIDAIRNDVDSTQVL 282
LRD R TR L+WG+PVP + + + YVWFDA Y++
Sbjct: 241 LRDGLRQRCITRDLKWGVPVPHEKYKDKVFYVWFDAPIGYVSI----------------- 283
Query: 283 HNNRSFIEKPKEWWENTEHV-----IGKDIIKFHTVYWXXXXXXX----XXXXXNRVVVH 333
+ + ++WW+N E+V +GKD + FHTV + V +
Sbjct: 284 --TSCYTSEWEKWWKNPENVELYQFMGKDNVPFHTVMFPSTQLGTEENWTLMKTISVTEY 341
Query: 334 GHWLSGGVKMSKSLGNVVDPIQIISYYGADTTRWYLLENSNIESDGNFIEKNLW-ETREL 392
++ G SK +G + ++ + + R+YLL N SD +F +L +
Sbjct: 342 LNYEDGKFSKSKGVGVFGNDVKDTN-IPVEVWRYYLLTNRPEVSDTSFSWTDLQAKLNGE 400
Query: 393 LCSKLGNLINRCGGKKFSLASGVELFSGKPIEE-LSSVFPKESQAEFTALLKSLDNCTE- 450
L S LGN +NR V F KP SV P AE +L KSL E
Sbjct: 401 LLSNLGNFVNR-----------VLSFIAKPDNAGYGSVIPDAHDAESHSLTKSLAEKVEK 449
Query: 451 ---SVNNCFQQYDITGAQKILWNIINEANSFIQSTEPWSKKGLEKDLIVYSAMEAARISL 507
++ + K I +E N ++Q+++ W +K L AA +
Sbjct: 450 FVAEYVEAMEKVKLKQGLKTAMLISSEGNYYLQASQFWKLYKEDKPLCAVVIRTAAGLVH 509
Query: 508 IFSQ---PIIPNIAERLLNRLDV 527
+ +Q P +P+ + + +L++
Sbjct: 510 LLAQLLEPFMPSFSCEVFKQLNL 532
>Hs14043022_2 [J] KOG1247 Methionyl-tRNA synthetase
Length = 669
Score = 92.4 bits (228), Expect = 2e-18
Identities = 133/551 (24%), Positives = 220/551 (39%), Gaps = 82/551 (14%)
Query: 14 ITTPIFYPNAKPHLGHLYSSLL-CDVQNRWKKLAGQDTCFTTGVDEHGLKIQLAAQQKGY 72
IT+ + Y N PHLG++ +L DV R+ +L +T + G DE+G + A ++G
Sbjct: 37 ITSALPYVNNVPHLGNIIGCVLSADVFARYSRLRQWNTLYLCGTDEYGTATETKALEEGL 96
Query: 73 SNPKAFVDELCE--HFVHLD--KDANIKFTRFIRTTDPDHVNNVKKLWNLCYNNGYIYKG 128
+ E+C+ H +H D + NI F F RTT P + ++ G++ +
Sbjct: 97 TP-----QEICDKYHIIHADIYRWFNISFDIFGRTTTPQQTKITQDIFQQLLKRGFVLQD 151
Query: 129 EHKGWYSVSDETFYPDTKILKLTIDGPPIPYDGS----FDPDAKYINSES---------R 175
+ F D + + P Y+ + D K IN+ R
Sbjct: 152 TVEQLRCEHCARFLADRFVEGVC---PFCGYEEARGDQCDKCGKLINAVELKKPQCKVCR 208
Query: 176 NEVTYQSELNYFFKLSAFQEPLIKLL-RENPTFIYPPLRHSQILRELESNELRDISVSRP 234
+ QS + F L ++ L + L R P + P ++Q + + LRD R
Sbjct: 209 SCPVVQSSQHLFLDLPKLEKRLEEWLGRTLPGSDWTP--NAQFITR---SWLRDGLKPRC 263
Query: 235 ATR-LQWGIPVPED--ESQKVYVWFDALCNYLTSIGGIDAIRNDVDSTQVLHNNRSFIEK 291
TR L+WG PVP + E + YVWFDA YL+ ++ ++
Sbjct: 264 ITRDLKWGTPVPLEGFEDKVFYVWFDATIGYLSI-------------------TANYTDQ 304
Query: 292 PKEWWENTEHV-----IGKDIIKFHTVYW--XXXXXXXXXXXXNRVVVHGHWLSGGVKMS 344
+ WW+N E V + KD + FH++ + + ++ + K S
Sbjct: 305 WERWWKNPEQVDLYQFMAKDNVPFHSLVFPCSALGAEDNYTLVSHLIATEYLNYEDGKFS 364
Query: 345 KSLG-NVVDPIQIISYYGADTTRWYLLENSNIESDGNFIEKN-LWETRELLCSKLGNLIN 402
KS G V + + AD R+YLL D F + L + L + LGN IN
Sbjct: 365 KSRGVGVFGDMAQDTGIPADIWRFYLLYIRPEGQDSAFSWTDLLLKNNSELLNNLGNFIN 424
Query: 403 RCGGKKFSLASGVELFSGKPIEELSSVFPKESQAEFTALLKSLDNCTESVNNCFQQYDIT 462
R G V F G + E+ V + Q LL + + + ++ I
Sbjct: 425 RAG-------MFVSKFFGGYVPEM--VLTPDDQ----RLLAHVTLELQHYHQLLEKVRIR 471
Query: 463 GAQKILWNIINEANSFIQSTEPWSK-KGLEKD-----LIVYSAMEAARISLIFSQPIIPN 516
A + + I N +IQ EPW + KG E D + A+ A + + QP +P
Sbjct: 472 DALRSILTISRHGNQYIQVNEPWKRIKGSEADRQRAGTVTGLAVNIAALLSVMLQPYMPT 531
Query: 517 IAERLLNRLDV 527
++ + +L +
Sbjct: 532 VSATIQAQLQL 542
>ECU11g0890 [J] KOG1247 Methionyl-tRNA synthetase
Length = 550
Score = 87.8 bits (216), Expect = 4e-17
Identities = 121/454 (26%), Positives = 191/454 (41%), Gaps = 59/454 (12%)
Query: 11 KFHITTPIFYPNAKPHLGHLYSSLLC-DVQNRWKKLAGQDTCFTTGVDEHGLKIQLAAQQ 69
K IT+ + Y N +PHLG++ S+L DV +R+ K G+ + + G DE+G I++ A
Sbjct: 2 KKFITSALPYVNNQPHLGNIIGSVLSGDVYSRYCKKKGEVSVYICGTDEYGTAIEMEAIS 61
Query: 70 KGYSNPKAFVDELCEHFVHLDKDA----NIKFTRFIRTTDPDHVNNVKKLWNLCYNNGYI 125
+G + E+CE L K NI F F T+ H V+ L+ Y+NG+
Sbjct: 62 QGVTPL-----EICEKNRKLHKQVYDWFNIDFDYFGFTSSATHTGLVQDLFMKMYDNGHF 116
Query: 126 YKGEHKGWYSVSDETFYPDTKIL-KLTIDGPPIPYDGSFDPDAKYINSES---------R 175
+ E + +Y F D I+ + G D NS
Sbjct: 117 SEVEIEQFYCEHCGLFLADRFIVGECKFCGDGRARGDQCDSCGHTYNSLELLSPRCSICS 176
Query: 176 NEVTYQSELNYFFKLSAFQEPLIKLLRENPTFIYPPLRHSQILRELESNELRDISVSRPA 235
+ ++ + FF L AF+ L +L R N ++ I R+ S E ++R
Sbjct: 177 SSPVVRATTHLFFDLEAFRPSLEELYRTNGHLWSQNAQN--IFRQWISMEFYPRCMTRD- 233
Query: 236 TRLQWGIPVP-EDESQKV-YVWFDALCNYLTSIGGIDAIRNDVDSTQVLHNNRSFIEKPK 293
+ WG+PVP E +KV YVWFDA YLT + + E
Sbjct: 234 LKFNWGVPVPLEKFKEKVFYVWFDAPIGYLTFLKELVG------------------EDFG 275
Query: 294 EWWENTEHV--IGKDIIKFHTVYWXXXXXXXXXX--XXNRVVVHGHWLSGGVKMSKSLGN 349
EW ++ E V +GKD + FHTV + R+ + K SKS +
Sbjct: 276 EWCKDAELVQFMGKDNVAFHTVIFPAMLYATGEKYPVVRRLSATEYLQFENEKFSKSRRH 335
Query: 350 VVDPIQIISYYGADTTRW--YLLE---NSNIESDGNFIEKNLWETRELLCSKLGNLINR- 403
+ + ++ + W YLL+ S +S+ F + T +L+ + LGN +NR
Sbjct: 336 GIFGLDLVGGGLGKSCMWRYYLLKIRPESTKDSNFTFSDFRQSVTADLI-NNLGNFVNRV 394
Query: 404 ---CGGKKFSLASGVELFSG--KPIEELSSVFPK 432
K S S +EL SG K IE+++ ++ K
Sbjct: 395 LKYIQSKCNSRVSLLELDSGDKKCIEDVNELYCK 428
>SPBC17A3.04c [J] KOG1247 Methionyl-tRNA synthetase
Length = 782
Score = 84.7 bits (208), Expect = 3e-16
Identities = 103/422 (24%), Positives = 166/422 (38%), Gaps = 65/422 (15%)
Query: 14 ITTPIFYPNAKPHLGHLYSSLL-CDVQNRWKKLAGQDTCFTTGVDEHGLKIQLAAQQKGY 72
IT+ + Y N PHLG++ S L DV R+ + +T + G DE+G + A ++G
Sbjct: 226 ITSALPYVNNVPHLGNIVGSTLSADVFARYHRARNHNTLYICGTDEYGTATETKALEEGV 285
Query: 73 SNPKAFVDELCEHFVHLDKDA----NIKFTRFIRTTDPDHVNNVKKLWNLCYNNGY---- 124
S PK ELC+ + L K+ I F F RTT P + ++ YNN Y
Sbjct: 286 S-PK----ELCDKYHALHKEVYDWFEIDFDHFGRTTTPKQTGIAQHIFTKLYNNDYMAID 340
Query: 125 ----IYKGEHKGWYS------VSDETFYPDTKILKLTIDGPPIPYDGSFDPDAKYINSES 174
+Y H+G+ + + Y D + + G + DP K
Sbjct: 341 TMTQLYCEVHQGYLADRYVEGTCPKCGYDDARGDQCDGCGGLLNAFELIDPKCKL----D 396
Query: 175 RNEVTYQSELNYFFKLSAFQEPLIKLLRENPTFIYPPLRHSQILRELESNELRDISVSRP 234
R + + F L Q + ++ + S R + + L++ R
Sbjct: 397 RATPVKRETKHVFLSLDKLQPAVESWAMQSAV----EGKWSNNGRSITESWLKEGLRPRC 452
Query: 235 ATR-LQWGIPVPEDE--SQKVYVWFDALCNYLTSIGGIDAIRNDVDSTQVLHNNRSFIEK 291
TR L+WG PVP +E + +YVWFDA Y++ ++ ++
Sbjct: 453 ITRDLKWGTPVPLEEFKGKVLYVWFDATIGYISI-------------------TANYTDE 493
Query: 292 PKEWWENTEHV-----IGKDIIKFHTVYWXXXXXXX----XXXXXNRVVVHGHWLSGGVK 342
++WW N E V +GKD + FHTV + + ++ +G
Sbjct: 494 WEKWWRNPEQVKLYQFMGKDNVPFHTVIFPSSLLGTGEKWTMLHHINTTDYLNYETGKFS 553
Query: 343 MSKSLGNVVDPIQIISYYGADTTRWYLLENSNIESDGNFIEKN-LWETRELLCSKLGNLI 401
S+ +G + Q I R+YLL + SD F K + L + LGN +
Sbjct: 554 KSRGVGVFGNTAQDIG-LSPSVWRYYLLSSRPETSDTMFTWKEFITRHNSELLANLGNFV 612
Query: 402 NR 403
NR
Sbjct: 613 NR 614
>CE06007_1 [J] KOG1247 Methionyl-tRNA synthetase
Length = 754
Score = 79.0 bits (193), Expect = 2e-14
Identities = 135/550 (24%), Positives = 214/550 (38%), Gaps = 95/550 (17%)
Query: 14 ITTPIFYPNAKPHLGHLYSSLL-CDVQNRWKKLAGQDTCFTTGVDEHGLKIQLAAQQKGY 72
IT + Y N PHLG++ +L DV R+ L G T + G DE+G + A Q+G
Sbjct: 39 ITAALPYVNNVPHLGNIIGCVLSADVFARYCNLRGHQTFYVGGTDEYGTATETKALQEGC 98
Query: 73 SNPKAFVDELCEHFVHLDKDA----NIKFTRFIRTTDPDHVNNVKKLWNLCYNNGYIYKG 128
+ P+ ELC+ + + K I F+ F RTT + ++ + NGY
Sbjct: 99 T-PR----ELCDKYHAIHKGIYEWFGIDFSHFGRTTTDHQTEICQDMFLKLHKNGYTSSQ 153
Query: 129 EHKGWYSVSDETFYPDTKILKLTIDGPPIPYDGS----FDPDAKYINS-ESRNEVTYQSE 183
Y E F D + T P YD + D K IN+ + ++ + +
Sbjct: 154 SVDQLYCNQCEKFLADRFV---TGTCPMCAYDDARGDQCDGCGKLINAVDLKDAKCHMCK 210
Query: 184 LNYFFKLSAFQEPLIKLLRENPTFIYPPLRHSQILRELESNELRDISVSRPATR------ 237
K S + L++ T + REL + R S + T+
Sbjct: 211 ATPEVKQSTHIFLSLDKLQQKTT--------EHLDRELAKEDNRWSSNAVGITKAWMKLG 262
Query: 238 ---------LQWGIPVPED--ESQKVYVWFDALCNYLTSIGGIDAIRNDVDSTQVLHNNR 286
L+WG VP D E + YVWFDA YL+ + VL +N
Sbjct: 263 LDPRCITRDLKWGTAVPLDGFEKKVFYVWFDAPIGYLSI------------TKCVLGDNW 310
Query: 287 SFIEKPKEWWENTEHV-----IGKDIIKFHTVYW--XXXXXXXXXXXXNRVVVHGHWLSG 339
+ +WW+N E+V +GKD + FH V + N + +
Sbjct: 311 T------KWWKNPENVELFNFVGKDNVAFHAVMFPCSQLGANDNYTVVNNLCATEYLNYE 364
Query: 340 GVKMSKSLGNVV--DPIQIISYYGADTTRWYLLENSNIESDGNFI-EKNLWETRELLCSK 396
K SKS G + D Q + AD R+YLL D F + + + L +
Sbjct: 365 DTKFSKSRGTGIFGDAAQ-GTEIPADIWRFYLLYMRPESQDTAFSWDDFVLKVNSELLNN 423
Query: 397 LGNLINRCGGKKFSLASGVELFSGKPIEELSSVFPKESQAEFTA-LLKSLDNCTESVNNC 455
LGN INR +L+ F G V P+ + A +L + N +
Sbjct: 424 LGNFINR------ALSFVANSFGG--------VVPEMNLTNDDAEVLSEIHNECMQWDKQ 469
Query: 456 FQQYDITGAQKILWNIINEANSFIQSTEPW-----SKKGLEK--DLIVYSAMEAARISLI 508
F + A K + N+ N ++Q+ PW ++G ++ +I +A A +S++
Sbjct: 470 FDGVHLKDAVKTILNVSRLGNQYMQAQTPWVLMKKDEEGKKRAGTIIGVAANIAYHVSVL 529
Query: 509 FSQPIIPNIA 518
PI+P I+
Sbjct: 530 L-YPIMPTIS 538
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.318 0.136 0.416
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,541,794
Number of Sequences: 60738
Number of extensions: 1502121
Number of successful extensions: 3482
Number of sequences better than 1.0e-05: 11
Number of HSP's better than 0.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 3428
Number of HSP's gapped (non-prelim): 17
length of query: 568
length of database: 30,389,216
effective HSP length: 112
effective length of query: 456
effective length of database: 23,586,560
effective search space: 10755471360
effective search space used: 10755471360
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)