ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI4006 good A KOG2375 RNA processing and modification Protein interacting with poly(A)-binding protein
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI4006 1397024 1399138 705
(705 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YGR178c [A] KOG2375 Protein interacting with poly(A)-binding pro... 426 e-119
SPBC21B10.03c [A] KOG2375 Protein interacting with poly(A)-bindi... 145 2e-34
At3g14010 [A] KOG2375 Protein interacting with poly(A)-binding p... 98 5e-20
At1g54170 [A] KOG2375 Protein interacting with poly(A)-binding p... 80 1e-14
ECU11g1020 [A] KOG2375 Protein interacting with poly(A)-binding ... 78 4e-14
Hs4506795 [A] KOG2375 Protein interacting with poly(A)-binding p... 60 1e-08
Hs9665245 [A] KOG2375 Protein interacting with poly(A)-binding p... 57 1e-07
Hs6005699 [A] KOG2375 Protein interacting with poly(A)-binding p... 57 1e-07
Hs22068961 [A] KOG2375 Protein interacting with poly(A)-binding ... 57 1e-07
>YGR178c [A] KOG2375 Protein interacting with poly(A)-binding protein
Length = 722
Score = 426 bits (1094), Expect = e-119
Identities = 248/581 (42%), Positives = 331/581 (56%), Gaps = 86/581 (14%)
Query: 27 SSSFYETASVKKSFDERQDFLLVNGIGNRAIVTITSGVKYEGLVAAWNPHSSGKGIGVVL 86
SS FYE + ++FD+RQD+LL N IG+ VT+TSGVKY GL+ + N S+ GI VVL
Sbjct: 35 SSMFYENPEITRNFDDRQDYLLANSIGSDVTVTVTSGVKYTGLLVSCNLESTN-GIDVVL 93
Query: 87 KYPKVLDKGFDESDINALSAELSETLTIEPKDVAGVKL--FDVSLDSDPLAAKEEESNPV 144
++P+V D G +S ++ L+ L ETL I +DVA ++L D+SLD +K +E+ P
Sbjct: 94 RFPRVADSGVSDS-VDDLAKTLGETLLIHGEDVAELELKNIDLSLDEKWENSKAQETTPA 152
Query: 145 ESG--KQAAEGETSQKDAFKTDTAISGAPKELKERELQKWSPDE-SESFPLNN-TSLEDD 200
+ K+ GE+++ F+TD ISG+ +E+KER+L+KW+P+E +E F +N +LEDD
Sbjct: 153 RTNIEKERVNGESNEVTKFRTDVDISGSGREIKERKLEKWTPEEGAEHFDINKGKALEDD 212
Query: 201 NGTWDQFAVNEKKFGIKPSFDEHFYTTRINKEDPEYQKKLNEAERIAKEIESQGASGNVH 260
+ +WDQFAVNEKKFG+K +FDEH YTT+INK+DP Y K+L EAERIAKEIESQG SGN+H
Sbjct: 213 SASWDQFAVNEKKFGVKSTFDEHLYTTKINKDDPNYSKRLQEAERIAKEIESQGTSGNIH 272
Query: 261 IDEDRNIKYDDSGLDEEDKYSGVDRRGDELLAQLKLNAKPEA-KGVRYVPPSLRSQPHHA 319
I EDR I DDSGLDEED YSGVDRRGDELLA LK N+KP + KG RYVPP+LR QPHH
Sbjct: 273 IAEDRGIIIDDSGLDEEDLYSGVDRRGDELLAALKSNSKPNSNKGNRYVPPTLRQQPHHM 332
Query: 320 DPAILXXXXX---------------------------------XXXXXXXEIADLKSFSE 346
DPAI+ +I +LK FSE
Sbjct: 333 DPAIISSSNSNKNENAVSTDTSTPAAAGAPEGKPPQKTSKNKKSLSSKEAQIEELKKFSE 392
Query: 347 KFKIPYDMPDEVKTILKKDDQHVKEKEEQXXXXXXXXXXXXXXXXXXXXXXXXLKSNXXX 406
KFK+PYD+P ++ +LK+ +K K+
Sbjct: 393 KFKVPYDIPKDMLEVLKRSSSTLKSNSSLPPKPIS-------------------KTPSAK 433
Query: 407 XXXXXXXXXXXXXLANASGGKGSNRSSKAGTPALGKIEVRRGSQNKFNGSGKTPIASPSM 466
+ SG S S G +RR + F G+ K P +
Sbjct: 434 TVSPTTQISAGKSESRRSGSNISQGQSSTGHTTRSSTSLRRRNHGSFFGA-KNPHTND-- 490
Query: 467 ARAETFGRRRQRNFFDEGKPKCLKKDLNKNFNMFLKAKEAHESKGK-DSEGKNLERFFIE 525
A+ FG K+FNMF+K+KEAH+ K K D +N+E FFIE
Sbjct: 491 AKRVLFG---------------------KSFNMFIKSKEAHDEKKKGDDASENMEPFFIE 529
Query: 526 KPYFTSPTWVSTVDQSYKSLFPDERTAIQRTQMRLQQRSID 566
KPYFT+PTW++T+++SYK+ FPDE TAIQ Q R QQR ++
Sbjct: 530 KPYFTAPTWLNTIEESYKTFFPDEDTAIQEAQTRFQQRQLN 570
>SPBC21B10.03c [A] KOG2375 Protein interacting with poly(A)-binding protein
Length = 791
Score = 145 bits (366), Expect = 2e-34
Identities = 93/247 (37%), Positives = 136/247 (54%), Gaps = 23/247 (9%)
Query: 99 SDINALSAELSETLTIEPKDVAGVKLFDVSLDSDPLAAKEEESNP-----------VESG 147
S + A ++++++ T + ++V +K+ + +AAK +S+ V S
Sbjct: 28 SAVAARGSKIAQSATNDHRNVESIKVVPENRVRGGVAAKATDSSSNVTSLASSEENVSSV 87
Query: 148 KQAAEGETSQKDAFKTDTAISGAPK-ELKERELQKWSPD-ESESFPLNNTSLEDDNGTWD 205
+A+ SQ+ +KTD AIS + E ++REL++W PD E PL DN WD
Sbjct: 88 SGSAKSNNSQQRVWKTDVAISAEKRTETRQRELRRWMPDPEDAGVPLAGLEESTDNVEWD 147
Query: 206 QFAVNEKKFGIKPSFDEHFYTTRINKEDPEYQKKLNEAERIAKEIESQGASGNVHIDEDR 265
QFA NEK FG+K FDE YT+RI++ P+Y++K EA+RIAKEIE + N+HI E+R
Sbjct: 148 QFATNEKLFGVKSHFDEDLYTSRIDRSHPKYKEKEQEADRIAKEIEGT-VTNNIHIAEER 206
Query: 266 NIKYDDSGLDEEDKYSGVDRRGDELLAQLKLNA--------KPEAKGVRYVPPSLRSQPH 317
+K DDSGLDEED YSGV R D + + NA KP+ + P + P
Sbjct: 207 GLKVDDSGLDEEDLYSGVHRSIDVVRNYTRSNAYNKNNKDQKPKNHEAPHQHPQQKVVPP 266
Query: 318 HADPAIL 324
DPAI+
Sbjct: 267 D-DPAIV 272
>At3g14010 [A] KOG2375 Protein interacting with poly(A)-binding protein
Length = 627
Score = 97.8 bits (242), Expect = 5e-20
Identities = 77/270 (28%), Positives = 132/270 (48%), Gaps = 32/270 (11%)
Query: 20 NAAFNGTSSSFYETASVKKSFDERQDFLLVNGIGNRAIVTITSGVKYEGLVAAWNPHSSG 79
N FNG E S+K+ +R + IG+ V + +G Y G+ A N
Sbjct: 31 NTVFNG------EAGSLKRLSLDRLVYFTTCKIGHHVEVHLRNGSVYTGIFHAANVE--- 81
Query: 80 KGIGVVLKYPKVLDKGF---DESDINALSAELSETLTIEPKDVAGVKLFDVSLDSDPLAA 136
K G++LK ++ G +S + S+T I ++ V D+S+ S+ ++
Sbjct: 82 KDFGIILKMACLIKDGTLRGHKSRSEFVRKPPSKTFIIPADELVQVIAKDLSVSSNNMSN 141
Query: 137 KEEESNPVESGKQAAEGETSQKDAFKTDTAISGAPKELKERELQKWSPDES--ESFPLNN 194
+ P E TD++IS + +ER+LQ+W PDE+ L N
Sbjct: 142 AVQGEKPSE---------------LLTDSSISQSYHVDRERQLQRWVPDETIPHGADLEN 186
Query: 195 TSLEDDNGTWDQFAVNEKKFGIKPSFDEHFYTTRINKEDPEYQKKLNEAERIAKEIESQG 254
N W+QF VN+ FG+K +FDE YTTR+ + P+ ++ A++IA+EIE++
Sbjct: 187 VFDNPWNRKWNQFEVNKSLFGVKSTFDEDLYTTRLER-GPQTKQLEEHAQKIAREIEAE- 244
Query: 255 ASGNVHIDEDRNIKYDDS-GLDEEDKYSGV 283
+ ++H+ E+R ++ +++ DEE +YS V
Sbjct: 245 TTRDIHVAEERGLQLNENFDFDEEARYSSV 274
>At1g54170 [A] KOG2375 Protein interacting with poly(A)-binding protein
Length = 587
Score = 80.1 bits (196), Expect = 1e-14
Identities = 67/235 (28%), Positives = 111/235 (46%), Gaps = 24/235 (10%)
Query: 52 IGNRAIVTITSGVKYEGLVAAWNPHSSGKGIGVVLKYPKVLDKGFDESDINALSAELSET 111
IG++ V + +G Y G+ A N K G++LK ++ + + +S S+
Sbjct: 60 IGHQVEVHLKNGSVYSGIFHAANVE---KDFGIILKMACLI-RDSRGTKSRTVSKPSSKL 115
Query: 112 LTIEPKDVAGVKLFDVSLDSDPLAAKEEESNPVESGKQAAEGETSQKDAFKTDTAISGAP 171
L I ++ V D+ L SD ++ + P+E TD+ IS
Sbjct: 116 LKIPADELVQVIAKDLPLSSDSVSDSVQCEKPLE---------------LLTDSLISQFY 160
Query: 172 KELKERELQKWSPDES--ESFPLNNTSLEDDNGTWDQFAVNEKKFGIKPSFDEHFYTTRI 229
EREL+ W PDE + L N + W+QF VN+ FG+ +FDE YTT++
Sbjct: 161 NVDLERELKPWVPDEDVPDCSDLENVFDDPWKRGWNQFEVNKTLFGVTSTFDEELYTTKL 220
Query: 230 NKEDPEYQKKLNEAERIAKEIESQGASGNVHIDEDRNIKYDDS-GLDEEDKYSGV 283
+ P ++ +A RIA+EI + + ++H+ E+R ++ +DEE KYS V
Sbjct: 221 ER-GPGTRELEEQALRIAREIVGEN-TRDIHVAEERGLQLSGKFDIDEETKYSSV 273
>ECU11g1020 [A] KOG2375 Protein interacting with poly(A)-binding protein
Length = 352
Score = 78.2 bits (191), Expect = 4e-14
Identities = 54/161 (33%), Positives = 80/161 (49%), Gaps = 17/161 (10%)
Query: 130 DSDPLAAKEEESNPVESGKQAAEGETSQKD-----AFKTDTAISGAPKELKERELQKWSP 184
+SD + + E GK A+E + K+ +F+TD+ ISG PKE+ E L K +
Sbjct: 51 ESDIITVTKMNGRQAEKGKDASERGSGAKEDSGWSSFRTDSEISGGPKEMPEAVLPKAAD 110
Query: 185 DESESFPLNNTSLEDDNGTWDQFAVNEKKFGIKPSFDEHFYTTRINKEDPEYQKKLNEAE 244
E SLE++ W+QF N K F I FDE Y ++K Y+ K++ A
Sbjct: 111 LEK--------SLEEECKDWNQFEANSKLFNIDSRFDEEEYMEVLDKSSESYKSKVSMAR 162
Query: 245 RIAKEIESQGASGNVHIDEDRNIKYDDSGLDEEDKYSGVDR 285
RI KEI A+ + H E+R + + ++ ED YS V R
Sbjct: 163 RIEKEI-MLSATTDAHRLEERGL---GNSVENEDIYSSVVR 199
>Hs4506795 [A] KOG2375 Protein interacting with poly(A)-binding protein
Length = 1312
Score = 59.7 bits (143), Expect = 1e-08
Identities = 64/283 (22%), Positives = 116/283 (40%), Gaps = 58/283 (20%)
Query: 43 RQDFLLVNGIGNRAIVTITSGVKYEGLVAAWNPHSSGKGIGVVLKYPKVLDKGFD---ES 99
R +L + +G++ V + +G YEG+ ++P K VLD + ES
Sbjct: 266 RMVHILTSVVGSKCEVQVKNGGIYEGVFKTYSP-----------KCDLVLDAAHEKSTES 314
Query: 100 DINALSAELSETLTIEPKDVAGVKLFDVSLDSDPLAAKEEESNPVESGKQAAEGETSQKD 159
E+ E++ + D V+ D+ + +++D
Sbjct: 315 SSGPKREEIMESILFKCSDFVVVQFKDM------------------------DSSYAKRD 350
Query: 160 AFKTDTAISGAPK-ELKERELQKWSPDESESFPLNNTSLEDDNGTW---DQFAVNEKKFG 215
AF TD+AIS E KE++L+ W E + D + W D F NE+ +G
Sbjct: 351 AF-TDSAISAKVNGEHKEKDLEPWDAGELTANEELEALENDVSNGWDPNDMFRYNEENYG 409
Query: 216 IKPSFDEHF--YTTRINKED-PEYQKKLNEAERIAKEIESQGASGNVHIDEDRNIKYDDS 272
+ ++D YT + +++ E+ K+ A ++A+EIES + ++
Sbjct: 410 VVSTYDSSLSSYTVPLERDNSEEFLKREARANQLAEEIESSA-------QYKARVALEND 462
Query: 273 GLDEEDKYSGVDRRGDELLAQLKLNAKPEAKGVRYVPPSLRSQ 315
EE+KY+ V R E +N + +Y+PP R++
Sbjct: 463 DRSEEEKYTAVQRNSSEREGH-SINTREN----KYIPPGQRNR 500
>Hs9665245 [A] KOG2375 Protein interacting with poly(A)-binding protein
Length = 484
Score = 56.6 bits (135), Expect = 1e-07
Identities = 50/141 (35%), Positives = 77/141 (54%), Gaps = 22/141 (15%)
Query: 158 KDAFKTDTAISGAPK---ELKERELQKWSPDESESFPLNNTSLEDD--NGTWD---QFAV 209
KD F TD+AI+ K E KE+ LQ+W +S S ++ LE D NG WD F
Sbjct: 289 KDKF-TDSAIAMNSKVNGEHKEKVLQRWEGGDSNS---DDYDLESDMSNG-WDPNEMFKF 343
Query: 210 NEKKFGIKPSFDEHF--YTTRINKEDPE-YQKKLNEAERIAKEIESQGASGNVHIDEDRN 266
NE+ +G+K ++D YT + K++ E ++++ A ++A+EIES S + R
Sbjct: 344 NEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLAREIES---SPQYRL---RI 397
Query: 267 IKYDDSGLDEEDKYSGVDRRG 287
+D G EE+K+S V R+G
Sbjct: 398 AMENDDGRTEEEKHSAVQRQG 418
>Hs6005699 [A] KOG2375 Protein interacting with poly(A)-binding protein
Length = 1051
Score = 56.6 bits (135), Expect = 1e-07
Identities = 50/141 (35%), Positives = 77/141 (54%), Gaps = 22/141 (15%)
Query: 158 KDAFKTDTAISGAPK---ELKERELQKWSPDESESFPLNNTSLEDD--NGTWD---QFAV 209
KD F TD+AI+ K E KE+ LQ+W +S S ++ LE D NG WD F
Sbjct: 289 KDKF-TDSAIAMNSKVNGEHKEKVLQRWEGGDSNS---DDYDLESDMSNG-WDPNEMFKF 343
Query: 210 NEKKFGIKPSFDEHF--YTTRINKEDPE-YQKKLNEAERIAKEIESQGASGNVHIDEDRN 266
NE+ +G+K ++D YT + K++ E ++++ A ++A+EIES S + R
Sbjct: 344 NEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLAREIES---SPQYRL---RI 397
Query: 267 IKYDDSGLDEEDKYSGVDRRG 287
+D G EE+K+S V R+G
Sbjct: 398 AMENDDGRTEEEKHSAVQRQG 418
>Hs22068961 [A] KOG2375 Protein interacting with poly(A)-binding protein
Length = 284
Score = 56.6 bits (135), Expect = 1e-07
Identities = 50/141 (35%), Positives = 77/141 (54%), Gaps = 22/141 (15%)
Query: 158 KDAFKTDTAISGAPK---ELKERELQKWSPDESESFPLNNTSLEDD--NGTWD---QFAV 209
KD F TD+AI+ K E KE+ LQ+W +S S ++ LE D NG WD F
Sbjct: 83 KDKF-TDSAIAMNSKVNGEHKEKVLQRWEGGDSNS---DDYDLESDMSNG-WDPNEMFKF 137
Query: 210 NEKKFGIKPSFDEHF--YTTRINKEDPE-YQKKLNEAERIAKEIESQGASGNVHIDEDRN 266
NE+ +G+K ++D YT + K++ E ++++ A ++A+EIES S + R
Sbjct: 138 NEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLAREIES---SPQYRL---RI 191
Query: 267 IKYDDSGLDEEDKYSGVDRRG 287
+D G EE+K+S V R+G
Sbjct: 192 AMENDDGRTEEEKHSAVQRQG 212
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.309 0.129 0.364
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,528,991
Number of Sequences: 60738
Number of extensions: 1589393
Number of successful extensions: 4629
Number of sequences better than 1.0e-05: 9
Number of HSP's better than 0.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 4609
Number of HSP's gapped (non-prelim): 11
length of query: 705
length of database: 30,389,216
effective HSP length: 113
effective length of query: 592
effective length of database: 23,525,822
effective search space: 13927286624
effective search space used: 13927286624
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)