ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI4024 good I KOG1298 Lipid transport and metabolism Squalene monooxygenase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI4024 1403958 1405457 500
(500 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YGR175c [I] KOG1298 Squalene monooxygenase 765 0.0
SPBC713.12 [I] KOG1298 Squalene monooxygenase 312 6e-85
Hs4507197 [I] KOG1298 Squalene monooxygenase 268 2e-71
At1g58440 [I] KOG1298 Squalene monooxygenase 247 3e-65
At4g37760 [I] KOG1298 Squalene monooxygenase 243 4e-64
At2g22830 [I] KOG1298 Squalene monooxygenase 231 2e-60
At5g24150 [I] KOG1298 Squalene monooxygenase 157 3e-38
At5g24160 [I] KOG1298 Squalene monooxygenase 154 2e-37
At5g24140 [I] KOG1298 Squalene monooxygenase 147 3e-35
>YGR175c [I] KOG1298 Squalene monooxygenase
Length = 496
Score = 765 bits (1975), Expect = 0.0
Identities = 363/491 (73%), Positives = 425/491 (85%)
Query: 10 IPKELLSASSEIVYDAIXXXXXXXXPCIATGLARKGKKVLIVERDWTMPDRIVGELMQPG 69
+ EL++A + I YDAI PC+ATGLARKGKKVLIVERDW MPDRIVGELMQPG
Sbjct: 6 VAPELINADNTITYDAIVIGAGVIGPCVATGLARKGKKVLIVERDWAMPDRIVGELMQPG 65
Query: 70 GLRALRSLGMIQAINNIDAIPVTGYSVFYNGEKVSIPYPYKADTAPVEKISDLVFDGNDR 129
G+RALRSLGMIQ+INNI+A PVTGY+VF+NGE+V IPYPYKAD VEK+ DLV DGND+
Sbjct: 66 GVRALRSLGMIQSINNIEAYPVTGYTVFFNGEQVDIPYPYKADIPKVEKLKDLVKDGNDK 125
Query: 130 VIEDKTVHVKDFEDDDRERGVGFVHGKFLQNLRDIVAKEPNVTRLQGNVIEILRSKENEV 189
V+ED T+H+KD+EDD+RERGV FVHG+FL NLR+I A+EPNVTR+QGN IEIL+ ++NEV
Sbjct: 126 VLEDSTIHIKDYEDDERERGVAFVHGRFLNNLRNITAQEPNVTRVQGNCIEILKDEKNEV 185
Query: 190 VGAKVEIPGRGKEDFKAHLTFVCDGIFSRFRKELSPDHIPSVGSSFVGMSLFHANIPSKN 249
VGAKV+I GRGK +FKAHLTF+CDGIFSRFRKEL PDH+P+VGSSFVGMSLF+A P+
Sbjct: 186 VGAKVDIDGRGKVEFKAHLTFICDGIFSRFRKELHPDHVPTVGSSFVGMSLFNAKNPAPM 245
Query: 250 HGHVILGTSHMPVLVYQISSEETRILCAYNSARLPKDIKSWLTTDVKPYLPKSLLPSFDK 309
HGHVILG+ HMP+LVYQIS EETRILCAYNS ++P DIKSW+ DV+P++PKSL PSFD+
Sbjct: 246 HGHVILGSDHMPILVYQISPEETRILCAYNSPKVPADIKSWMIKDVQPFIPKSLRPSFDE 305
Query: 310 AVEDGKFRSMPNSYLPAKQNTVTGLCVIGDALNMRHPLTGGGMAVGLNDVALLIKTVGDL 369
AV GKFR+MPNSYLPA+QN VTG+CVIGDALNMRHPLTGGGM VGL+DV LLIK +GDL
Sbjct: 306 AVSQGKFRAMPNSYLPARQNDVTGMCVIGDALNMRHPLTGGGMTVGLHDVVLLIKKIGDL 365
Query: 370 DFSDRETVLDELLEYHFERKQYDSVINVLSIALYSLFAADNRNLQVLQRGCFKYFERGGD 429
DFSDRE VLDELL+YHFERK YDSVINVLS+ALYSLFAAD+ NL+ LQ+GCFKYF+RGGD
Sbjct: 366 DFSDREKVLDELLDYHFERKSYDSVINVLSVALYSLFAADSDNLKALQKGCFKYFQRGGD 425
Query: 430 CIRLPVSFLAGVLPKPFLLTKVFFSVALYSIYVNFQERGILGSPLALLEAFAILFTAAKV 489
C+ PV FL+GVLPKP LT+VFF+VA Y+IY+N +ERG LG P+ALLE IL TA +V
Sbjct: 426 CVNKPVEFLSGVLPKPLQLTRVFFAVAFYTIYLNMEERGFLGLPMALLEGIMILITAIRV 485
Query: 490 FTPYLFKELIG 500
FTP+LF ELIG
Sbjct: 486 FTPFLFGELIG 496
>SPBC713.12 [I] KOG1298 Squalene monooxygenase
Length = 457
Score = 312 bits (800), Expect = 6e-85
Identities = 177/469 (37%), Positives = 257/469 (54%), Gaps = 40/469 (8%)
Query: 37 IATGLARKGKKVLIVERDWTMPDRIVGELMQPGGLRALRSLGMIQAINNIDAIPVTGYSV 96
+ L R+G+KVL++ERD + PDRIVGEL+QPGG+ AL +G+ A+ ID +GY +
Sbjct: 20 LGAALGRQGRKVLVLERDMSEPDRIVGELLQPGGIEALEKIGIADAVEGIDGQWTSGYQI 79
Query: 97 FYNGEKVSIPYPYKADTAPVEKISDLVFDGNDRVIEDKTVHVKDFEDDDRERGVGFVHGK 156
FY VS+PYP K + + G+GF +G+
Sbjct: 80 FYGDSNVSVPYPSKPNGGAYQ-------------------------------GIGFHYGR 108
Query: 157 FLQNLRDIVAKEPNVTRLQGNVIEILRSKENEVVGAKVEIPGRGKE--DFKAHLTFVCDG 214
F+ NLR + PNVT + V E+LR + EV+ V + + ++KA LT VCDG
Sbjct: 109 FVMNLRKALTSTPNVTVTEATVNELLRDETGEVITGVVTSSKKSESPVEYKAPLTIVCDG 168
Query: 215 IFSRFRKELSPDHIPSVGSSFVGMSLFHANIPSKNHGHVILGTSHMPVLVYQISSEETRI 274
FS+FRK DH V F+G+ L + + + GHVIL + P+++Y ISS E RI
Sbjct: 169 CFSKFRKAFI-DHPIQVTDHFLGLILTNPDYIAPGRGHVIL-SKVAPMVLYPISSTEARI 226
Query: 275 LCAYNSARLP--KDIKSWLTTDVKPYLPKSLLPSFDKAVEDGKFRSMPNSYLPAKQNTVT 332
L Y LP + +K ++ P +P+ L PS AV + + RSMPN +LP N
Sbjct: 227 LINYPGKNLPPMETLKKYVLESCVPNMPEKLRPSLKAAVYNDRLRSMPNQFLPPTVNRTK 286
Query: 333 GLCVIGDALNMRHPLTGGGMAVGLNDVALLIKTVGDL---DFSDRETVLDELLEYHFERK 389
G+ ++GD+ NMRHPLTGGGM V +D LL + + D D E +L+++ ++H++RK
Sbjct: 287 GMILVGDSNNMRHPLTGGGMTVCFHDAYLLSRFISPSAVPDLLDYERILNQMNKFHWKRK 346
Query: 390 QYDSVINVLSIALYSLFAADNRNLQVLQRGCFKYFERGGDCIRLPVSFLAGVLPKPFLLT 449
Y VINVLSIALY LF NR ++ L+ GC YF+RGG+C+ P+ L G+ P L
Sbjct: 347 GYSFVINVLSIALYKLFTPKNRYMKALESGCIDYFKRGGNCVEGPIRLLGGLDHSPSHLI 406
Query: 450 KVFFSVALYSIYVNFQERGILGSPLALLEAFAILFTAAKVFTPYLFKEL 498
F++V LY IY L P+ ++E+ I A+ V PY+ E+
Sbjct: 407 GHFYAVCLYGIYQYVLSGPALLMPVRIIESLLIFLQASLVIIPYILSEM 455
>Hs4507197 [I] KOG1298 Squalene monooxygenase
Length = 574
Score = 268 bits (684), Expect = 2e-71
Identities = 165/488 (33%), Positives = 257/488 (51%), Gaps = 40/488 (8%)
Query: 16 SASSEIVYDAIXXXXXXXXPCIATGLARKGKKVLIVERDWTMPDRIVGELMQPGGLRALR 75
S SS+ + I + L+R G+KV ++ERD PDRIVGE +QPGG L+
Sbjct: 117 STSSQNDPEVIIVGAGVLGSALVAVLSRDGRKVTVIERDLKEPDRIVGEFLQPGGYHVLK 176
Query: 76 SLGMIQAINNIDAIPVTGYSVFYNGEK--VSIPYPYKADTAPVEKISDLVFDGNDRVIED 133
LG+ + +DA V GY + K V IPYP
Sbjct: 177 DLGLGDTVEGLDAQVVNGYMIHDQESKSEVQIPYPLS----------------------- 213
Query: 134 KTVHVKDFEDDDRERGVGFVHGKFLQNLRDIVAKEPNVTRLQGNVIEILRSKENEVVGAK 193
E++ + G F HG+F+ +LR EPN ++G V+++L +++ V+G +
Sbjct: 214 --------ENNQVQSGRAFHHGRFIMSLRKAAMAEPNAKFIEGVVLQLL-EEDDVVMGVQ 264
Query: 194 VEIPGRGK-EDFKAHLTFVCDGIFSRFRKELSPDHIPSVGSSFVGMSLFHANIPSKNHGH 252
+ G ++ A LT V DG+FS+FRK L + + SV S FVG + +A NH
Sbjct: 265 YKDKETGDIKELHAPLTVVADGLFSKFRKSLVSNKV-SVSSHFVGFLMKNAPQFKANHAE 323
Query: 253 VILGTSHMPVLVYQISSEETRILCAYNSARLPKDIKSWLTTDVKPYLPKSLLPSFDKAVE 312
+IL + PVL+Y+ISS ETR+L +P++++ ++ + P +P L F +A +
Sbjct: 324 LIL-ANPSPVLIYRISSSETRVLVDIR-GEMPRNLREYMVEKIYPQIPDHLKEPFLEATD 381
Query: 313 DGKFRSMPNSYLPAKQNTVTGLCVIGDALNMRHPLTGGGMAVGLNDVALLIKTV-GDLDF 371
+ RSM S+LP G+ ++GDA NMRHPLTGGGM V D+ L K + G D
Sbjct: 382 NSHLRSMLASFLPPSSVKKRGVLLLGDAYNMRHPLTGGGMTVAFKDIKLWRKLLKGIPDL 441
Query: 372 SDRETVLDELLEYHFERK-QYDSVINVLSIALYSLFAADNRNLQVLQRGCFKYFERGGDC 430
D + + +++ RK + V+N+L+ ALY LF+A + +L L++ CF YF+ GG+C
Sbjct: 442 YDDAAIFEANKSFYWARKTSHSFVVNILAQALYELFSATDDSLHQLRKACFLYFKLGGEC 501
Query: 431 IRLPVSFLAGVLPKPFLLTKVFFSVALYSIYVNFQERGILGSPLALLEAFAILFTAAKVF 490
+ PV L+ + P P L FF+VA+Y++Y F+ + P ALL + A+L+ A V
Sbjct: 502 VAGPVGLLSVLSPNPLALIGHFFAVAIYAVYFCFKSEPWITKPRALLSSSAVLYKACSVI 561
Query: 491 TPYLFKEL 498
P ++ E+
Sbjct: 562 FPLIYSEM 569
>At1g58440 [I] KOG1298 Squalene monooxygenase
Length = 535
Score = 247 bits (630), Expect = 3e-65
Identities = 157/456 (34%), Positives = 235/456 (51%), Gaps = 44/456 (9%)
Query: 15 LSASSEIVYDAIXXXXXXXXPCIATGLARKGKKVLIVERDWTMPDRIVGELMQPGGLRAL 74
++ + + V D I +A L + ++V ++ERD + PDRIVGEL+QPGG L
Sbjct: 53 VNITGDTVADVIVVGAGVAGSALAYTLGKDKRRVHVIERDLSEPDRIVGELLQPGGYLKL 112
Query: 75 RSLGM----IQAINNIDAIPVTGYSVFYNGEKVSIPYPYKADTAPVEKISDLVFDGNDRV 130
LG+ + IDA V GY++F NG+++ + YP
Sbjct: 113 LELGIEGLSTDCVEEIDAQRVYGYALFKNGKRIRLAYP---------------------- 150
Query: 131 IEDKTVHVKDFEDDDRERGVGFVHGKFLQNLRDIVAKEPNVTRLQGNVIEILRSKENEVV 190
++ F +D G F +G+F+Q +R+ A PNV QG V+ +L + +
Sbjct: 151 -------LEKFHED--VSGRSFHNGRFIQRMREKAASLPNVQLEQGTVLSLLE-ENGTIK 200
Query: 191 GAKVEIPGRGKEDFKAHLTFVCDGIFSRFRKELSPDHIPSVGSSFVGMSLFHANIPSKNH 250
G + + ++ A LT VCDG FS R+ L + V S FVG+ L + N+P NH
Sbjct: 201 GVRYKNKAGEEQTAFAALTIVCDGCFSNLRRSLCNPQV-EVPSCFVGLVLENCNLPYANH 259
Query: 251 GHVILGTSHMPVLVYQISSEETRILCAYNSARLPK----DIKSWLTTDVKPYLPKSLLPS 306
GHV+L P+L+Y ISS E R L ++P ++K++L T V P +P + S
Sbjct: 260 GHVVLADPS-PILMYPISSTEVRCLVDVPGQKVPSIANGEMKNYLKTVVAPQMPHEVYDS 318
Query: 307 FDKAVEDGKFRSMPNSYLPAKQNTVTGLCVIGDALNMRHPLTGGGMAVGLNDVALLIKTV 366
F AV+ G +SMPN +PA G ++GDA NMRHPLTGGGM V L D+ +L +
Sbjct: 319 FIAAVDKGNIKSMPNRSMPASPYPTPGALLMGDAFNMRHPLTGGGMTVALADIVVLRNLL 378
Query: 367 GDL-DFSDRETVLDELLEYHFERKQYDSVINVLSIALYSLF-AADNRNLQVLQRGCFKYF 424
L D SD ++ L ++ RK + IN L+ ALY +F +++N ++ CF Y
Sbjct: 379 RPLRDLSDGASLCKYLESFYTLRKPVAATINTLANALYQVFCSSENEARNEMREACFDYL 438
Query: 425 ERGGDCIRLPVSFLAGVLPKPFLLTKVFFSVALYSI 460
GG C PVS L+G+ P+P L FF+VA+Y +
Sbjct: 439 GLGGMCTSGPVSLLSGLNPRPLTLVCHFFAVAVYGV 474
>At4g37760 [I] KOG1298 Squalene monooxygenase
Length = 530
Score = 243 bits (621), Expect = 4e-64
Identities = 158/458 (34%), Positives = 238/458 (51%), Gaps = 47/458 (10%)
Query: 15 LSASSEIVYDAIXXXXXXXXPCIATGLARKGKKVLIVERDWTMPDRIVGELMQPGGLRAL 74
L+ S D I +A L ++G++V ++ERD T PDRIVGEL+QPGG L
Sbjct: 47 LTVKSGTDVDIIIVGAGVAGAALAHTLGKEGRRVHVIERDLTEPDRIVGELLQPGGYLKL 106
Query: 75 RSLGMIQAINNIDAIPVTGYSVFYNGEKVSIPYPYKADTAPVEKISDLVFDGNDRVIEDK 134
LG+ + +IDA V GY++F +G+ + YP
Sbjct: 107 IELGLEDCVKDIDAQRVLGYALFKDGKHTKLSYP-------------------------- 140
Query: 135 TVHVKDFEDDDRERGVGFVHGKFLQNLRDIVAKEPNVTRLQGNVIEILRSKENEVVGAKV 194
+ F+ D G F +G+F+Q +R+ + PNV QG V ++ +EN ++ V
Sbjct: 141 ---LDQFDSD--VAGRSFHNGRFVQRMREKASLLPNVRMEQGTVTSLV--EENGIIKG-V 192
Query: 195 EIPGRGKEDFK--AHLTFVCDGIFSRFRKELSP----DHIPSVGSSFVGMSLFHANIPSK 248
+ + ++ K A LT VCDG FS R+ L + + V S+FVG+ L + +P
Sbjct: 193 QYKTKDGQELKSFAPLTIVCDGCFSNLRRSLCKPKVCNMVVEVPSNFVGLVLENCELPFP 252
Query: 249 NHGHVILGTSHMPVLVYQISSEETRILCAYNSARLPK----DIKSWLTTDVKPYLPKSLL 304
NHGHV+LG P+L Y ISS E R L ++LP ++ L T V P +P +
Sbjct: 253 NHGHVVLG-DPSPILFYPISSSEVRCLVDVPGSKLPSVASGEMAHHLKTMVAPQVPPQIR 311
Query: 305 PSFDKAVEDGKFRSMPNSYLPAKQNTVTGLCVIGDALNMRHPLTGGGMAVGLNDVALLIK 364
+F AVE G R+MPN +PA G ++GDA NMRHPLTGGGM V L+D+ +L
Sbjct: 312 DAFISAVEKGNIRTMPNRSMPADPIHTPGALLLGDAFNMRHPLTGGGMTVALSDIVILRD 371
Query: 365 TVGDL-DFSDRETVLDELLEYHFERKQYDSVINVLSIALYSLFAADNRNLQ-VLQRGCFK 422
+ L D +++E++ + ++ RK S IN L+ ALY +F A + + ++R CF
Sbjct: 372 LLNPLVDLTNKESLSKYIESFYTLRKPVASTINTLAGALYKVFLASPDDARSEMRRACFD 431
Query: 423 YFERGGDCIRLPVSFLAGVLPKPFLLTKVFFSVALYSI 460
Y GG C PV+ L+G+ P+P L FF+VA++ +
Sbjct: 432 YLSLGGVCSSGPVALLSGLNPRPMSLVLHFFAVAIFGV 469
>At2g22830 [I] KOG1298 Squalene monooxygenase
Length = 585
Score = 231 bits (589), Expect = 2e-60
Identities = 149/443 (33%), Positives = 223/443 (49%), Gaps = 40/443 (9%)
Query: 24 DAIXXXXXXXXPCIATGLARKGKKVLIVERDWTMPDRIVGELMQPGGLRALRSLGMIQAI 83
D I +A L ++G++V ++ERD++ DRIVGEL+QPGG L LG+ +
Sbjct: 124 DVIIVGAGVAGSALAHTLGKEGRRVHVIERDFSEQDRIVGELLQPGGYLKLIELGLEDCV 183
Query: 84 NNIDAIPVTGYSVFYNGEKVSIPYPYKADTAPVEKISDLVFDGNDRVIEDKTVHVKDFED 143
IDA V GY +F +G+ + YP ++ F+
Sbjct: 184 KKIDAQRVLGYVLFKDGKHTKLAYP-----------------------------LETFDS 214
Query: 144 DDRERGVGFVHGKFLQNLRDIVAKEPNVTRLQGNVIEILRSKENEVVGAKVEIPGRGKED 203
D G F +G+F+Q +R+ NV QG V +L + + G + +
Sbjct: 215 D--VAGRSFHNGRFVQRMREKALTLSNVRLEQGTVTSLL-EEHGTIKGVRYRTKEGNEFR 271
Query: 204 FKAHLTFVCDGIFSRFRKELSPDHIPSVGSSFVGMSLFHANIPSKNHGHVILGTSHMPVL 263
A LT VCDG FS R+ L + V S+FVG+ L + +P NHGHV+LG P+L
Sbjct: 272 SFAPLTIVCDGCFSNLRRSLCKPKV-DVPSTFVGLVLENCELPFANHGHVVLG-DPSPIL 329
Query: 264 VYQISSEETRILCAYNSARLPK----DIKSWLTTDVKPYLPKSLLPSFDKAVEDGKFRSM 319
+Y ISS E R L +LP ++ +L T V P +P + +F AVE G R+M
Sbjct: 330 MYPISSSEVRCLVDVPGQKLPPIANGEMAKYLKTRVAPQVPTKVREAFITAVEKGNIRTM 389
Query: 320 PNSYLPAKQNTVTGLCVIGDALNMRHPLTGGGMAVGLNDVALLIKTVGDL-DFSDRETVL 378
PN +PA G ++GDA NMRHPLTGGGM V L D+ +L + + + +D+E +
Sbjct: 390 PNRSMPADPIPTPGALLLGDAFNMRHPLTGGGMTVALADIVVLRDLLRPIRNLNDKEALS 449
Query: 379 DELLEYHFERKQYDSVINVLSIALYSLFAADNRNLQV-LQRGCFKYFERGGDCIRLPVSF 437
+ ++ RK S IN L+ ALY +F A + + ++ CF Y GG PV+
Sbjct: 450 KYIESFYTLRKPVASTINTLADALYKVFLASSDEARTEMREACFDYLSLGGVFSSGPVAL 509
Query: 438 LAGVLPKPFLLTKVFFSVALYSI 460
L+G+ P+P L FF+VA+Y++
Sbjct: 510 LSGLNPRPLSLVLHFFAVAIYAV 532
>At5g24150 [I] KOG1298 Squalene monooxygenase
Length = 516
Score = 157 bits (397), Expect = 3e-38
Identities = 125/481 (25%), Positives = 217/481 (44%), Gaps = 42/481 (8%)
Query: 24 DAIXXXXXXXXPCIATGLARKGKKVLIVERDWTMPDRIVGELMQPGGLRALRSLGMIQAI 83
D I +A LA+ G++V ++ERD P+RI+GE MQPGG L LG+ +
Sbjct: 47 DVIIVGAGVGGSALAYALAKDGRRVHVIERDLREPERIMGEFMQPGGRLMLSKLGLEDCL 106
Query: 84 NNIDAIPVTGYSVFYNGEKVSIPYPYKADTAPVEKISDLVFDGNDRVIEDKTVHVKDFED 143
IDA TG +V+ +G++ +P + P FD + R
Sbjct: 107 EGIDAQKATGMTVYKDGKEAVASFPVDNNNFP--------FDPSAR-------------- 144
Query: 144 DDRERGVGFVHGKFLQNLRDIVAKEPNVTRLQGNVIEILRSKENEVVGAKVEIPGRGKED 203
F +G+F+Q LR + PNV RL+ ++ L ++ + G + +
Sbjct: 145 -------SFHNGRFVQRLRQKASSLPNV-RLEEGTVKSLIEEKGVIKGVTYKNSAGEETT 196
Query: 204 FKAHLTFVCDGIFSRFRKELSPDHIPSVGSSFVGMSLFHANIPSKNHGHVILGTSHMPVL 263
A LT VCDG +S R+ L+ D+ V S VG + + +I+ +L
Sbjct: 197 ALAPLTVVCDGCYSNLRRSLN-DNNAEVLSYQVGFISKNCQLEEPEKLKLIMSKPSFTML 255
Query: 264 VYQISSEETRILCAYNSARLPK----DIKSWLTTDVKPYLPKSLLPSFDKAVEDGK-FRS 318
YQISS + R + +P ++ +++ + P +P L F K +++G+ ++
Sbjct: 256 -YQISSTDVRCVFEVLPNNIPSISNGEMATFVKNTIAPQVPLKLRKIFLKGIDEGEHIKA 314
Query: 319 MPNSYLPAKQNTVTGLCVIGDALNMRHPLTGGGMAVGLNDVALLIKTVGDL-DFSDRETV 377
MP + A + G+ ++GDA NMRHP GM V L+D+ +L + + L + + + +
Sbjct: 315 MPTKKMTATLSEKKGVILLGDAFNMRHPAIASGMMVLLSDILILRRLLQPLSNLGNAQKI 374
Query: 378 LDELLEYHFERKQYDSVINVLSIALYS-LFAADNRNLQVLQRGCFKYFERGGDCIRLPVS 436
+ ++ RK + +N L A L A+ + + +++GC+ Y GG ++
Sbjct: 375 SQVIKSFYDIRKPMSATVNTLGNAFSQVLVASTDEAKEAMRQGCYDYLSSGGFRTSGMMA 434
Query: 437 FLAGVLPKPFLLTKVFFSVALYSIYVNFQERGILGSPLALLEAFAILFTAAKVFTPYLFK 496
L G+ P+P L ++ L SI SPL + + + A K+ P+L
Sbjct: 435 LLGGMNPRPISLIYHLCAITLSSIGHLLSP---FPSPLRIWHSLRLFGLAMKMLVPHLKA 491
Query: 497 E 497
E
Sbjct: 492 E 492
>At5g24160 [I] KOG1298 Squalene monooxygenase
Length = 517
Score = 154 bits (390), Expect = 2e-37
Identities = 130/485 (26%), Positives = 215/485 (43%), Gaps = 49/485 (10%)
Query: 24 DAIXXXXXXXXPCIATGLARKGKKVLIVERDWTMPDRIVGELMQPGGLRALRSLGMIQAI 83
D I +A LA+ G++V ++ERD P+R++GE MQPGG L LG+ +
Sbjct: 47 DVIIVGAGVGGSALAYALAKDGRRVHVIERDMREPERMMGEFMQPGGRLMLSKLGLQDCL 106
Query: 84 NNIDAIPVTGYSVFYNGEKVSIPYPYKADTAPVEKISDLVFDGNDRVIEDKTVHVKDFED 143
+IDA TG +V+ +G++ P+P D N+ +E
Sbjct: 107 EDIDAQKATGLAVYKDGKEADAPFPV---------------DNNNF----------SYEP 141
Query: 144 DDRERGVGFVHGKFLQNLRDIVAKEPNVTRLQGNVIEILRSKENEVVGAKVEIPGRGKED 203
R F +G+F+Q LR NV RL+ ++ L ++ V G + +
Sbjct: 142 SARS----FHNGRFVQQLRRKAFSLSNV-RLEEGTVKSLLEEKGVVKGVTYKNKEGEETT 196
Query: 204 FKAHLTFVCDGIFSRFRKELSPDHIPSVGSSFVGMSLFHANIPSKNHGHVILGTSHMPVL 263
A LT VCDG +S R+ L+ D+ + S VG + + H+IL +
Sbjct: 197 ALAPLTVVCDGCYSNLRRSLNDDNNAEIMSYIVGYISKNCRLEEPEKLHLILSKPSF-TM 255
Query: 264 VYQISSEETRILCAYNSARLPK----DIKSWLTTDVKPYLPKSLLPSFDKAVEDGKFRSM 319
VYQISS + R P ++ +++ + P +P L F K +++G +
Sbjct: 256 VYQISSTDVRCGFEVLPENFPSIANGEMSTFMKNTIVPQVPPKLRKIFLKGIDEGAHIKV 315
Query: 320 PNSYLPAKQNTVT-----GLCVIGDALNMRHPLTGGGMAVGLNDVALLIKTVGDL-DFSD 373
+PAK+ T T G+ V+GDA NMRHP+ GM V L+D+ +L + + L + D
Sbjct: 316 ----VPAKRMTSTLSKKKGVIVLGDAFNMRHPVVASGMMVLLSDILILRRLLQPLSNLGD 371
Query: 374 RETVLDELLEYHFERKQYDSVINVLSIALYS-LFAADNRNLQVLQRGCFKYFERGGDCIR 432
V + + ++ RK + +N L A L + + + +++G + Y GG
Sbjct: 372 ANKVSEVINSFYDIRKPMSATVNTLGNAFSQVLIGSTDEAKEAMRQGVYDYLCSGGFRTS 431
Query: 433 LPVSFLAGVLPKPFLLTKVFFSVALYSIYVNFQERGILGSPLALLEAFAILFTAAKVFTP 492
++ L G+ P+P L ++ L SI Q SPL + + + A K+ P
Sbjct: 432 GMMALLGGMNPRPLSLVYHLCAITLSSI---GQLLSPFPSPLRIWHSLKLFGLAMKMLVP 488
Query: 493 YLFKE 497
L E
Sbjct: 489 NLKAE 493
>At5g24140 [I] KOG1298 Squalene monooxygenase
Length = 516
Score = 147 bits (372), Expect = 3e-35
Identities = 118/447 (26%), Positives = 207/447 (45%), Gaps = 43/447 (9%)
Query: 24 DAIXXXXXXXXPCIATGLARKGKKVLIVERDWTMPDRIVGELMQPGGLRALRSLGMIQAI 83
D I +A LA+ G++V ++ERD P R +GELMQ GG L LG+ +
Sbjct: 45 DVIIVGAGVAGASLAYALAKDGRRVHVIERDLKEPQRFMGELMQAGGRFMLAQLGLEDCL 104
Query: 84 NNIDAIPVTGYSVFYNGEKVSIPYPYKADTAPVEKISDLVFDGNDRVIEDKTVHVKDFED 143
+IDA +++ +G+ ++P+P + P E + L+ +G
Sbjct: 105 EDIDAQEAKSLAIYKDGKHATLPFP-DDKSFPHEPVGRLLRNG----------------- 146
Query: 144 DDRERGVGFVHGKFLQNLRDIVAKEPNVTRLQGNVIEILRSKENEVVGAKVEIPGRGKED 203
+ +Q LR A NV +L+ ++ L +E V G + +
Sbjct: 147 ------------RLVQRLRQKAASLSNV-QLEEGTVKSLIEEEGVVKGVTYKNSAGEEIT 193
Query: 204 FKAHLTFVCDGIFSRFRKELSPDHIPSVGSSFVGMSLFHANIPSKNHGHVILGTSHMPVL 263
A LT VCDG +S R+ L D+ V S VG ++ + + H+I + + +
Sbjct: 194 AFAPLTVVCDGCYSNLRRSLV-DNTEEVLSYMVGYVTKNSRLEDPHSLHLIF-SKPLVCV 251
Query: 264 VYQISSEETRILCAYNSARLPK----DIKSWLTTDVKPYLPKS--LLPSFDKAVEDG--K 315
+YQI+S+E R + + +P ++ ++L + P +P++ L F K +E+G +
Sbjct: 252 IYQITSDEVRCVAEVPADSIPSISNGEMSTFLKKSMAPQIPETGNLREIFLKGIEEGLPE 311
Query: 316 FRSMPNSYLPAKQNTVTGLCVIGDALNMRHPLTGGGMAVGLNDVALLIKTVGDL-DFSDR 374
+S + ++ G+ V+GDA NMRHP+ GM V L+D+ +L + L + S+
Sbjct: 312 IKSTATKSMSSRLCDKRGVIVLGDAFNMRHPIIASGMMVALSDICILRNLLKPLPNLSNT 371
Query: 375 ETVLDELLEYHFERKQYDSVINVL-SIALYSLFAADNRNLQVLQRGCFKYFERGGDCIRL 433
+ V D + ++ RK + +N L SI L A + + +++GCF Y RG R
Sbjct: 372 KKVSDLVKSFYIIRKPMSATVNTLASIFSQVLVATTDEAREGMRQGCFNYLARGDFKTRG 431
Query: 434 PVSFLAGVLPKPFLLTKVFFSVALYSI 460
++ L G+ P P L ++ L S+
Sbjct: 432 LMTILGGMNPHPLTLVLHLVAITLTSM 458
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.321 0.141 0.410
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,661,663
Number of Sequences: 60738
Number of extensions: 1315472
Number of successful extensions: 2851
Number of sequences better than 1.0e-05: 9
Number of HSP's better than 0.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 2798
Number of HSP's gapped (non-prelim): 15
length of query: 500
length of database: 30,389,216
effective HSP length: 111
effective length of query: 389
effective length of database: 23,647,298
effective search space: 9198798922
effective search space used: 9198798922
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)