ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI4045 good O KOG1140 Posttranslational modification, protein turnover, chaperones N-end rule pathway, recognition component UBR1
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI4045 1416293 1410459 -1945
(1945 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YGR184c [O] KOG1140 N-end rule pathway recognition component UBR1 1750 0.0
SPAC15A10.11 [O] KOG1140 N-end rule pathway recognition componen... 177 2e-43
YLR024c [O] KOG1140 N-end rule pathway recognition component UBR1 157 1e-37
CE08535 [O] KOG1140 N-end rule pathway recognition component UBR1 108 1e-22
Hs20555197 [O] KOG1140 N-end rule pathway recognition component ... 100 2e-20
7293307 [O] KOG1140 N-end rule pathway recognition component UBR1 90 3e-17
SPBC19C7.02 [O] KOG1140 N-end rule pathway recognition component... 82 7e-15
At5g02300 [O] KOG1140 N-end rule pathway recognition component UBR1 74 3e-12
Hs18597977 [O] KOG1140 N-end rule pathway recognition component ... 70 3e-11
>YGR184c [O] KOG1140 N-end rule pathway recognition component UBR1
Length = 1950
Score = 1750 bits (4532), Expect = 0.0
Identities = 933/1933 (48%), Positives = 1252/1933 (64%), Gaps = 77/1933 (3%)
Query: 11 LRQHVGRTLGCIHSRPEFKDIKGSAERAVMDKELKSFIYGYYYYMISDSGRLLPHMFTAT 70
L+ H+ RTL IH+ P F+ +G ERA M + LK FIY Y Y++IS+SG LP +F A
Sbjct: 11 LQGHIRRTLRSIHNLPYFRYTRGPTERADMSRALKEFIYRYLYFVISNSGENLPTLFNAH 70
Query: 71 NERE--------FPKNVDQAMEI-KLSSK---PWYKIDENGGHSKFNHAGRICGAKFRVG 118
+++ FP +++ A++I K++S+ P+YKIDE+ H GR CG KF++G
Sbjct: 71 PKQKLSNPELTVFPDSLEDAVDIDKITSQQTIPFYKIDESRIGDVHKHTGRNCGRKFKIG 130
Query: 119 EPIYRCKECSFDDTCVLCVNCFNPKDHVGHHVYTSICTEFNNGICDCGDKEAWNHELNCK 178
EP+YRC EC DDTCVLC++CFNPKDHV HHV T ICTEF +GICDCGD+EAWN L+CK
Sbjct: 131 EPLYRCHECGCDDTCVLCIHCFNPKDHVNHHVCTDICTEFTSGICDCGDEEAWNSPLHCK 190
Query: 179 GAED----------NGRLEDEFDDHDGKISKMLESVLIELFDHFIDVFNQNIEPLTTIQK 228
E N +++E +D ++E VL E+FD+FIDVFNQNIEPL TIQK
Sbjct: 191 AEEQENDISEDPATNADIKEEDVWNDSVNIALVELVLAEVFDYFIDVFNQNIEPLPTIQK 250
Query: 229 PLIAKLRYFIQNGKYNEQADMLRRLAYRNQYM-DEEESQQQTPSTSLDPLSTL-----KD 282
+ KLR Q GK E+A L L Y N YM D + + +PS S + +L ++
Sbjct: 251 DITIKLREMTQQGKMYERAQFLNDLKYENDYMFDGTTTAKTSPSNSPEASPSLAKIDPEN 310
Query: 283 YAILVYNDEFHNYSQASAAIRQGGPDNKHIDLLTAKIDSEGRSLLRCSADIASLMGGFFS 342
Y +++YNDE+HNYSQA+ A+RQG PDN HIDLLT++ID EGR++L+CS D++S++GGFF+
Sbjct: 311 YTVIIYNDEYHNYSQATTALRQGVPDNVHIDLLTSRIDGEGRAMLKCSQDLSSVLGGFFA 370
Query: 343 VQSNGLSCTITQWYEYLHQEACKYSIMWINDCLNIPNSTFQSLFRNAIGKVLCSKYEPFY 402
VQ+NGLS T+T W EYLHQE CKY I+WI CLNIPNS+FQ+ FRN +GK LCS+Y
Sbjct: 371 VQTNGLSATLTSWSEYLHQETCKYIILWITHCLNIPNSSFQTTFRNMMGKTLCSEYLNAT 430
Query: 403 QSIDMTSVVRDYFSDSYLSDDPYLYADHSVLGEGVKIPLGRHKSLDPGDISAISPILNKV 462
+ DMT VV YFS+ + +DPY Y D S+L +G +IPLG HK L ++SP++N V
Sbjct: 431 ECRDMTPVVEKYFSNKFDKNDPYRYIDLSILADGNQIPLGHHKILPESSTHSLSPLINDV 490
Query: 463 IAEDHHEYTNSRLQYVLFLENRYWKKLRKIVQDLIIPTLASSAVHKPMFTDQLVEIFPHM 522
Y+N+RLQ++L+ +NRYWK+LRK +Q++IIPTLASS ++KP+F Q+VEIF H+
Sbjct: 491 ETPTSRTYSNTRLQHILYFDNRYWKRLRKDIQNVIIPTLASSNLYKPIFCQQVVEIFNHI 550
Query: 523 TRSVTFMDREPQLTSLRESVVQLFTCPTTAYSIFHSGHFNYVIWSVIDVFVDFSTMDEGT 582
TRSV +MDREPQLT++RE VVQLFTCPT A +IF + F ++WS+ID+F +F ++ G
Sbjct: 551 TRSVAYMDREPQLTAIRECVVQLFTCPTNAKNIFENQSFLDIVWSIIDIFKEFCKVEGGV 610
Query: 583 LVWQRVQRSNPSKSYSISFKQGLYAVETLLSKITDPNLLLKPGEFIMIVTLCKLFNGAWK 642
L+WQRVQ+SN +KSYSISFKQGLY VETLLSK+ DPN+ L+P E I ++TLCKLFNGAWK
Sbjct: 611 LIWQRVQKSNLTKSYSISFKQGLYTVETLLSKVHDPNIPLRPKEIISLLTLCKLFNGAWK 670
Query: 643 IKRKEGEHVLREDQHFIPYLEYTTSVYSIIQTFDKVLQQSKDHIDQRLLIGAINLLDSFL 702
IKRKEGEHVL EDQ+FI YLEYTTS+YSIIQT +KV ++SKD ID +L + AI ++ SFL
Sbjct: 671 IKRKEGEHVLHEDQNFISYLEYTTSIYSIIQTAEKVSEKSKDSIDSKLFLNAIRIISSFL 730
Query: 703 GHRNLSYKL-YKDFEIIKFQISKERVSFMNPVHTLFSFLVQHVPLQVSIQVLSQSKDYLV 761
G+R+L+YKL Y E+IKF +S ERV+FMNP+ T+ SFL++ V L+ + + L D+L
Sbjct: 731 GNRSLTYKLIYDSHEVIKFSVSHERVAFMNPLQTMLSFLIEKVSLKDAYEALEDCSDFLK 790
Query: 762 ISDFALRSVVLCSQIDIGFWVRNGMSVLHQSAYYKNNPEMSSYSRDIQLNQLAFLIEKND 821
ISDF+LRSVVLCSQID+GFWVRNGMSVLHQ++YYKNNPE+ SYSRDI LNQLA L E++D
Sbjct: 791 ISDFSLRSVVLCSQIDVGFWVRNGMSVLHQASYYKNNPELGSYSRDIHLNQLAILWERDD 850
Query: 822 FQRVIYNMLDRWELLDWFDGSVPSTETVYDDKISSIIQQFVAFLYQILVERDFYKKFDTL 881
R+IYN+LDRWELLDWF G V TVY+DKIS IIQQF+AF+YQIL ER ++K F +L
Sbjct: 851 IPRIIYNILDRWELLDWFTGEVDYQHTVYEDKISFIIQQFIAFIYQILTERQYFKTFSSL 910
Query: 882 EETQLYNIKNAIIYKLYAEPLSYTDLLNDIPDYLTESVSQFDTVLEEVSTYIEPKGLEDN 941
++ ++ IKN+IIY LY +PLSY+ LL +PDYLTE ++FD LEEVS ++EPKGL DN
Sbjct: 911 KDRRMDQIKNSIIYNLYMKPLSYSKLLRSVPDYLTEDTTEFDEALEEVSVFVEPKGLADN 970
Query: 942 GVFKLKKELYKRIDSLRLLNMGNDFEHSATIVKSHLADSKEKRAKIIVKPQLLELDELDP 1001
GVFKLK LY ++D L+LLN+ N+FE SATI+KSHLA K++ AK+++ PQ + + +LD
Sbjct: 971 GVFKLKASLYAKVDPLKLLNLENEFESSATIIKSHLAKDKDEIAKVVLIPQ-VSIKQLDK 1029
Query: 1002 CARELGSFTRTNXXXXXXXXXXXXXVSDSSFSFTYELLHLIHAIFRDDEMVNGKDSLPEA 1061
A LG+FTR + +F ELLHL+H IFRDDE++NGKDS+PEA
Sbjct: 1030 DALNLGAFTRNTVFAKVVYKLLQVCLDMEDSTFLNELLHLVHGIFRDDELINGKDSIPEA 1089
Query: 1062 YISKPICDLLLSIVDSESGSFSENVVATADYLLDNMIMKRPTAVLESLTECFGTKYIADY 1121
Y+SKPIC+LLLSI +++S FSE++V ADYLL+ MIMK+P + ESL FG +Y+ DY
Sbjct: 1090 YLSKPICNLLLSIANAKSDVFSESIVRKADYLLEKMIMKKPNELFESLIASFGNQYVNDY 1149
Query: 1122 KIRKANQGVNFEETEQERKRRLAKNRQQQIMNRFSRQQKKFMDKHEEYSAGNDEDVDMDG 1181
K +K QGVN +ETE+ERKRRLAK Q +++ +F+ QQ KFM +HE D DVDM G
Sbjct: 1150 KDKKLRQGVNLQETEKERKRRLAKKHQARLLAKFNNQQTKFMKEHESEFDEQDNDVDMVG 1209
Query: 1182 EDLAGELNEFHCSLCHDDVSDDFFVIPIYQNYSPVFLSSNP-TPMEIYKPWHGFDNNEHL 1240
E + E +F C+LC D S DFFVIP Y ++SP+F N P E W GF N++
Sbjct: 1210 EKVY-ESEDFTCALCQDSSSTDFFVIPAYHDHSPIFRPGNIFNPNEFMPMWDGFYNDDEK 1268
Query: 1241 ATY-NTDLFYKKKENGASQLMHESTQKVLVSCNHAVHYRCFKHYIDKKRYSTDLFICPLC 1299
Y + D+ KENG+ ++KV VSCNH +H+ CFK Y+ KKR+S++ FICPLC
Sbjct: 1269 QAYIDDDVLEALKENGSC-----GSRKVFVSCNHHIHHNCFKRYVQKKRFSSNAFICPLC 1323
Query: 1300 QTYCNSVIPV-DTVKLQSG---DRLLQQKLTGGLDESLLLTFSEYSSECNDEVGKIILS- 1354
QT+ N +P+ T K +G D L+ +L+ L F+E + + + +++S
Sbjct: 1324 QTFSNCTLPLCQTSKANTGLSLDMFLESELSLDTLSRLFKPFTEENYRTINSIFSLMISQ 1383
Query: 1355 LKDSNNGLRLNRNDPTWIQDRFLTLSLQFSNNICMLEMLSRLNKDPFGTLLSGEEQKFKT 1414
+ + +R N +D L LS+ ++N I MLE+ SRL K + EQK+KT
Sbjct: 1384 CQGFDKAVRKRANFSH--KDVSLILSVHWANTISMLEIASRLEKPYSISFFRSREQKYKT 1441
Query: 1415 LQNILKSLAVYTRLTKHTEENVLKFYEDIRSSNLPSYPFFRVVETVLRSRLSFKDCLQEV 1474
L+NIL + ++T + + + + + F +V + L S +S + + E
Sbjct: 1442 LKNILVCIMLFTFVIGKPSMEFEPYPQQPDTVWNQNQLFQYIVRSALFSPVSLRQTVTEA 1501
Query: 1475 LVERLKGLTKDF-------GSFYRKYESELRAQTCLDSSEFSIVLKTTILGAGF-GDQVE 1526
L + +DF + Y + L SE + TI G E
Sbjct: 1502 LTTFSRQFLRDFLQGLSDAEQVTKLYAKASKIGDVLKVSEQMLFALRTISDVRMEGLDSE 1561
Query: 1527 KHTLDLFYTFLISELLPTLRRSIILLKALKQFMTGGDDLDFNEKDVLSG-----SLTSES 1581
DL YTFL+ LLPT+RR ++ +K L + + + NE V++G L E
Sbjct: 1562 SIIYDLAYTFLLKSLLPTIRRCLVFIKVLHELVKDSE----NETLVINGHEVEEELEFED 1617
Query: 1582 KEKHFHLLIRFLLQTDFYDLLMNSHSPLSPESSLVNAPHEYCSIIKLTDLATHLNTYVTN 1641
+ + ++ + + + L+ + + L N P+EYC IIKL DL+ +LNTYVT
Sbjct: 1618 TAEFVNKALKMITEKESLVDLLTTQESIVSHPYLENIPYEYCGIIKLIDLSKYLNTYVTQ 1677
Query: 1642 NKNITLREENDQKIRNTVNRLDYKICLICGVKIHARTDGLEMQKHMERCSHGSSGLFLIP 1701
+K I LREE Q ++N NRLD+KICL CGVK+H R D EM KH+ + G FL+P
Sbjct: 1678 SKEIKLREERSQHMKNADNRLDFKICLTCGVKVHLRADRHEMTKHLNKNCFKPFGAFLMP 1737
Query: 1702 NISQVCLYLSRPDCTVNISAPYLNSHGESGRNAIERGDLTVLNHARYEHLTRLWISNGIP 1761
N S+VCL+L++P + ISAPYLNSHGE GRNA+ RGDLT LN RYEHL RLWI+N IP
Sbjct: 1738 NSSEVCLHLTQPPSNIFISAPYLNSHGEVGRNAMRRGDLTTLNLKRYEHLNRLWINNEIP 1797
Query: 1762 GYISRVMGDEFRVA-MANNRTFTRNMFWRPGAAFNAGGESSDEDLMNDDEF--GNDDRPD 1818
GYISRVMGDEFRV ++N F N RP + D + D F GND+
Sbjct: 1798 GYISRVMGDEFRVTILSNGFLFAFNREPRPRRIPPTDEDDEDMEEGEDGFFTEGNDE--- 1854
Query: 1819 LRFRQPDVELRINGGPFGGDIPIRLPTERGDIHDFFEFVQNMRGGMQGDG---ADIPTTE 1875
D E FG G + DFF+F +N R +Q G D P
Sbjct: 1855 ---MDVDDETGQAANLFGVGAE---GIAGGGVRDFFQFFENFRNTLQPQGNGDDDAPQNP 1908
Query: 1876 DIIEQLQGNAMNG 1888
I Q G +G
Sbjct: 1909 PPILQFLGPQFDG 1921
>SPAC15A10.11 [O] KOG1140 N-end rule pathway recognition component UBR1
Length = 2052
Score = 177 bits (448), Expect = 2e-43
Identities = 236/1001 (23%), Positives = 404/1001 (39%), Gaps = 136/1001 (13%)
Query: 474 RLQYVLFLENRYWKKLRKIVQDLIIPTLASSAVHKPMFTDQLVEIFPHMTRSVTFMDREP 533
RL Y L + ++WK+LR ++ L + + + K + + V + + + F DREP
Sbjct: 594 RLDYFLLFDLKFWKRLRGLLSKLYVVPFNRNLLFKRLMGIRFVIHYRSLATAFLFADREP 653
Query: 534 QLTSLRESVVQLFTCPTTAYSIFHSGHFNYVIWSVIDVFVDFSTMDEGTLVWQRVQRSNP 593
+ + SV Q FT P+ A ++ DF T T + Q + P
Sbjct: 654 DHSVMFLSV-QFFTTPSLAEAVVKD--------------YDFLTNLNATTLSLLTQSNRP 698
Query: 594 SKSYS--------ISFKQGLYAVETLLSKITDPNLLLKPGEFIMIVT-----------LC 634
S +S I + + + +D LL+ + +V L
Sbjct: 699 STLFSSDIEYTPTIQLNRQVLKTRRTYNLFSDLGYLLQHPQVKKLVVDDTRYVHQYIDLL 758
Query: 635 KLFNGAWKIKRKEGEHVLREDQHFIPYLEYTTSVYSIIQTFDKVLQQSKDHIDQRLLIGA 694
++F G +R HV + H L V + T Q+ L A
Sbjct: 759 RVFQGVIPQQRAILSHVQWDFPHGKNILFVMQRVAMLSNTVSSCFTQAP----YERLFYA 814
Query: 695 INLLDSFLGHRNLSYKLYKDFE----------------IIKFQISKERVSFMNPVHTLFS 738
I + + + H L + + E ++ F +S++ +SF +P+H + S
Sbjct: 815 IKCIITSITHPKLD--IAESLEPLSCIPSSSLTNFTQPLVPFSVSRDPISFYHPLHWMLS 872
Query: 739 FLVQHVPLQVSIQVLSQSKDYLV-ISDFALRSVVLCSQIDIGFWVRNGMSVLHQSAYYK- 796
L + + S KD L+ + D LR VL +QID W+RNG S+L A+Y+
Sbjct: 873 NLFSYCRVDASSH---WDKDTLLALLDHPLRVCVLLAQIDCNLWIRNGRSILLTDAFYRQ 929
Query: 797 -NNPEMSSYSRDIQLNQLAFLIEKNDFQRVIYNMLDRWELLDWFDGSVPSTETVYD-DKI 854
NN E+S Y +DI Q + D V+ ++ R+E DW + YD ++I
Sbjct: 930 LNNIEVS-YDKDILAIQTILMFV--DPNLVLNAVVQRFEFTDWLYNLTYNEHPNYDTERI 986
Query: 855 SSIIQQFVAFLYQILVERDFYKKFDTLEETQLYNIKNAIIYKLYAEPLSYTDLLNDIPDY 914
+++ + + L ++ ER+ D + I+ + +L PL+Y+ LL+ I
Sbjct: 987 PAMLCKMLELLIALITEREQILHVDIQDI-----IRTRLAQQLCFGPLAYSALLSTISSN 1041
Query: 915 LTESVSQFDTVLEEVSTYIEPKGLEDNGVFKLKKELYKRIDSLRLLNMGNDFEHSATIVK 974
L ES+S FD + EEV++Y P GL D GV+ LK E Y +D N+ E S TI+K
Sbjct: 1042 LVESLS-FDKIREEVTSYKAPDGLHDFGVYSLKDEYYDLVDPYYFHYNKNEREESDTILK 1100
Query: 975 SHLADSKEKRAK-IIVKPQL--LELDELDPCARELGSFTRT----NXXXXXXXXXXXXXV 1027
LA A+ II++P++ LE D D + + T +
Sbjct: 1101 KRLAKKNNVSAESIIIEPKIRFLEKDGHDIFFAAVNASTFSLIIFRAIEYALVQAESFGS 1160
Query: 1028 SDSSFSFTYELLHLIHAIFRDDEMVNGKDSLPEAYISKPICDLLLSIVDSESGSFSENVV 1087
SD + + L L + E D + + D S + E G + +
Sbjct: 1161 SDIGNTILGDALQLCLISMKIHEFSKSNDFCSRSCAERYPTD---SSIMREFGGSAYCLA 1217
Query: 1088 ATADYLLDNMIMK----RPTAVLESLTECFGTKY-----IADYKIRKANQGVNFEETEQ- 1137
+L + K + AVL L + + Y +++ + + E E+
Sbjct: 1218 ELCFAILKSPKYKDVHVKVNAVLAGLQKNDPSAYSNMLEATHFELSTTSSTSDSNEIEKT 1277
Query: 1138 ERKRRLAKNRQQQIMNRFSRQQKKFMDKHEEYSAGNDEDVDMDGEDLAGELNEFH----- 1192
+ K+RLA +Q++IM +F QQ F+ ++ ++ G D+ D + E ++H
Sbjct: 1278 QEKKRLALEKQKKIMQQFRDQQASFLAQNTDFDIGEDQTEDEVTTEEPEEEVKYHEHIRG 1337
Query: 1193 -CSLCHDDVSDD--FFVIPIYQNYS---PVFLSSNPTPMEIYKPWHGFDNNEHL----AT 1242
C LC ++ +D + VI I Q S + S EIY D H
Sbjct: 1338 NCLLCQEECNDQAPYGVIGIIQGSSLLRKTDVHSEIILDEIYSVPPNLDRESHSRPFGKK 1397
Query: 1243 YNTDLFYKKKENGASQL-MHESTQKVLVS-CNHAVHYRCFK-HYIDKKRYSTDL------ 1293
Y+T +F + K+ S + + V VS C H +H CFK +Y+ + Y D+
Sbjct: 1398 YDTVVFNRSKDRLLSAYPPGNNIRGVFVSGCGHLMHLGCFKNYYVARSMYRNDVTAGLSE 1457
Query: 1294 ----------FICPLCQTYCNSVIPVDTVK---LQSGDRLLQQKLTGGLDESLLLTFSEY 1340
F+CPLC++ N ++P+ + L + + G L+E ++ S +
Sbjct: 1458 YYYKYSTAKFFMCPLCRSLSNVLLPMPQIPKMCLNIDTLNFPRSMNGWLEEIGTMSSSSF 1517
Query: 1341 SSECNDEVGKIILSLKDSNNGLRLNRNDPTWIQDRFLTLSL 1381
E + SL D+ + R P WI + ++ L
Sbjct: 1518 ------EYQLVRSSLSDTKDTFRSCFLRP-WINSKIISAML 1551
Score = 112 bits (280), Expect = 6e-24
Identities = 72/271 (26%), Positives = 124/271 (45%), Gaps = 32/271 (11%)
Query: 109 RICGAKFRVGEPIYRCKECSFDDTCVLCVNCFNPKDHVGHHVYTSICTEFNNGICDCGDK 168
++CG FR GE IYRCK C D+TCVLC CF+ +H GH + SI T + +GICDCGD
Sbjct: 96 KVCGHVFRAGEVIYRCKNCGLDNTCVLCAPCFHATNHEGHETHVSISTSY-SGICDCGDP 154
Query: 169 EAWNHELNCK--GAEDNGRLEDEFDDHDGKISKMLESVLIELFDHFIDVFNQNIEPLTTI 226
EAWN +LNCK D+ + + ++ + + + L D +DVF+ +
Sbjct: 155 EAWNVDLNCKIHNVPDDEEQKKPEEVIPLELQHSIRTTIHILLDFILDVFSCS------- 207
Query: 227 QKPLIAKLRYFIQNGKYNEQADMLRRLAYRNQYMDEEESQQQTPSTSLDPLSTLKDYAIL 286
P+ K + + + +E+A L Y + P + + ++
Sbjct: 208 --PVNLKAQSTVGSILADEEASRLSSAKY---------------GVADRPCNV---FRVM 247
Query: 287 VYNDEFHNYSQASAAIRQG-GPDNKHIDLLTA-KIDSEGRSLLRCSADIASLMGGFFSVQ 344
++NDE H + ++ + N L A ++DS GR + SA + + ++
Sbjct: 248 LWNDEVHTFDAVVGSVLEALDSSNTAFGLEVAQRVDSIGRFAVATSASVHEAIRIANAIS 307
Query: 345 SNGLSCTITQWYEYLHQEACKYSIMWINDCL 375
L+ + ++ ++ C + W +D L
Sbjct: 308 KENLAVNVRTARDFFREDICGILLEWFDDLL 338
>YLR024c [O] KOG1140 N-end rule pathway recognition component UBR1
Length = 1872
Score = 157 bits (398), Expect = 1e-37
Identities = 289/1310 (22%), Positives = 521/1310 (39%), Gaps = 208/1310 (15%)
Query: 610 TLLSKITDPN-LLLKPGEFIMIVTLCKLFNGAWKIKRKEGEHVLREDQHFIPYLEYTTSV 668
T++S T P LL F I+ F+ +KR+ EHV E+ F + + +S+
Sbjct: 606 TIMSANTVPEELLSNEAIFNAIIESFSEFSNVLPLKRETKEHVEVENFDFSAFYFFFSSI 665
Query: 669 YSIIQTFDKVLQQSKDHIDQRLLIGAINLLD-----SFLGHRNLSYKLYKD--------- 714
+ + + + KD ++ ++ + LLD F N + D
Sbjct: 666 LIMTDGYTRSISLVKDAAFRKQIV--LKLLDVAQTREFESLTNSRKAISPDNASTNENDS 723
Query: 715 ----------------FEIIKFQISKERVSFMNPVHTLFSFLVQ------HVPLQVSI-- 750
E I FQ+ F NP+ LF F++Q + P+ S+
Sbjct: 724 NKATLSTVRETICNYVAETINFQVGVNTQYFFNPMSYLFKFVIQWSQCGRYEPIPASLTN 783
Query: 751 -----QVLSQSKDYLVISDFALRSVVLCSQIDIGFWVRNGMSVLHQSAYY-KNNPEMSSY 804
+V + L IS+ AL ++VL QI++GFWVRNG + HQ+ Y K + +Y
Sbjct: 784 YINLFEVFQDKQKALYISESALSTLVLIGQINVGFWVRNGTPITHQARMYTKYSMREFTY 843
Query: 805 SRDIQLNQLAFLIEKNDFQRVIYNMLDRWELLDWFDG----SVPSTETVYDDKISSIIQQ 860
DI Q + + D V Y L RW L W +G P TET +++ +
Sbjct: 844 ISDIFNVQFSMAMCNPDELMVTY--LSRWGLKHWANGVPMYDYPDTETTV-----AVVNE 896
Query: 861 FVAFLYQILVE-RDFYKKFDTLEETQLYNIKNAIIYKLYAEPLSYTDLLNDIPDYLTESV 919
+ L Q+L E R K + +E K+ II+ L + SY ++N IP+++T+
Sbjct: 897 CILLLIQLLTEVRSLVMK--SSKEGFERTFKSEIIHALCFDTCSYAQIVNCIPEHITKHP 954
Query: 920 SQFDTVLEEVSTYIEPKGLEDNGVFKLKKELYKRIDSLRL-LNMGNDFEHSATIVKSHLA 978
S FD LE+ + Y P L DNG+F LK++ ID + L+ ++ I + ++A
Sbjct: 955 S-FDIYLEKYANYTSPVSLTDNGIFVLKEKYKDEIDPYYIGLSSSRRYDVEKNI-RLNMA 1012
Query: 979 DSKEKRAKIIVKPQLLELDEL-DPCARELGSFTRTNXXXXXXXXXXXXXVSDSSFSFTYE 1037
+ K+ + + P D L + L S + N + +
Sbjct: 1013 NLKKMKYEDTFVPAKKVKDLLKNTLFSGLYSISSVNTFGLFLKNTLDHIIKYDYDNLLPR 1072
Query: 1038 LLHLIH-AIFRDDEMVNGKDSLPEAYISKPICD-------LLLSIVDSESGSFSENVVAT 1089
++HLIH + + G A + C L ++ +
Sbjct: 1073 VVHLIHLCVVNNLNEFMGILWHEYAIVDTEFCHYHSIGSILYYCLLKDNFSESHGKIREI 1132
Query: 1090 ADYLLDNMIMKRPTAVLESLTECFGTKYIADYKIRKANQGVNFEETEQERKRRLAKNRQQ 1149
YL++ + L T + + K K++ ++ E ERK+ LA+ R++
Sbjct: 1133 FRYLMETAPHVNVNSYLREQTTSYTPGILWPTKEDKSH-----KDKEFERKKHLARLRKK 1187
Query: 1150 QIMNRFSRQQKKFMDKHE---------EYSAGNDEDVDMDGEDLAGELN---EFHCSLCH 1197
++M + ++QQ KFM+ + ++ + ++ E+ + +N + C C
Sbjct: 1188 KLMKKLAQQQMKFMENNSVDTSDISTPRTTSPSLSPTRINAENSSNTINSCCDDDCVFCK 1247
Query: 1198 DDVSDDFFVIPIYQNYSPVFLSSNPT-PMEIYKPWHGFDNNEHLATYNTDLFYKKKENGA 1256
DD FV YQ + + T P ++ + F + T ++ + +++
Sbjct: 1248 MPKDDDVFVYFSYQERNICDHGIDFTNPTDVNRINSLFSGKQ---TKDSAIQENPQDDDG 1304
Query: 1257 SQLMHESTQKVLVSCNHAVHYRCFKHYIDKKR-------------YSTDLFICPLCQTYC 1303
++L S + VL +C H H +C ++ R Y + L CP+C +
Sbjct: 1305 TRLKFTSCEPVLRACGHGSHTKCLSGHMKSIRGIQNQTTKNIPLSYGSGLIYCPVCNSLS 1364
Query: 1304 NSVIPV--DTVKLQSGDRLLQQKLTGGLDESLLLTFSEYSSECNDEVGKIILSLKDSNNG 1361
NS +P D K S + + +E+L SS C K + L D
Sbjct: 1365 NSFLPKTNDIDKRTSSQFFMCIEKRSEAEENL----DPMSSICI----KAAMILGD---- 1412
Query: 1362 LRLNRNDPTWIQDRFLTLSLQFSNNICMLEMLSRLNKDPFGTLLSGE---EQKFKTLQNI 1418
L T I+D + ++ F N I E+ R +K G +++ E Q TL +
Sbjct: 1413 --LQGKKVTTIEDAYKVVNSVFINTISNTELRLRSHKKE-GKIVNMERISSQCILTLHLV 1469
Query: 1419 --LKSLAVYTR---------------------LTKHTEENVLKF----YEDIRSSNLPSY 1451
LKS +Y + L K N+L + +++I P
Sbjct: 1470 CELKSF-IYKKFVNSKTFSSEISRKIWNWNEFLIKGNNVNLLLYMSQNFDNIDGGKTPQP 1528
Query: 1452 PFFRVVETVLRSRLSFKDCLQEVLVERLKGLTKDFGSFYRKYESELRAQTC---LDSSEF 1508
P + E FK ++L+ + + + +FY+ ++++ + S+ F
Sbjct: 1529 PNLCIYE-------MFKRRFHQLLLLLARDMMR--VNFYKDCRNKIKISSNGSEEPSTSF 1579
Query: 1509 SIVLKT----TILGAGFGDQVEKHTLDLFYTFLISELLPTL----RRSIILLKALKQFMT 1560
S + T L + + +L+ F+ S LL +L RR+ +L Q+
Sbjct: 1580 SYLFNTFKKYVDLFKPDDVRFDFTSLEKIKDFICSLLLESLSIFCRRTFLLFNI--QYDD 1637
Query: 1561 GGDDLDFNEKDVLSGSLTSESKEKHFHLLIRFLLQTDFYDLLMN-SHSPLSPESSLVNAP 1619
GD + N + + + K++ L+ R+ + L + ++ L+ N
Sbjct: 1638 DGDGDNNNNR----SNNFMDVKQREIELIFRYFKLPNLTHFLKDFFYNELTQNIERYNDG 1693
Query: 1620 HEYCSIIK-LTDLATHLNTYV-TNNKNITLRE----------ENDQKIRNTVNRLDYKIC 1667
++ I + + D+ ++NT + ++I L E +ND+ I N ++ + +C
Sbjct: 1694 NDNLRIQQVIYDMVQNINTRAYPSPEHIQLIELPLNLSKFSLDNDE-ISNKCDKYEIAVC 1752
Query: 1668 LICGVKIHARTDGL-------EMQKHMER-CSHGSS-GLFLIPNISQVCLYLSRPDCTVN 1718
L+CG K H + E HM C S+ G+FL+ + +YLS
Sbjct: 1753 LLCGQKCHIQKSIALQGYLQGECTDHMRNGCEITSAYGVFLMTGTN--AIYLSYGKRGTF 1810
Query: 1719 ISAPYLNSHGESGRNAIERGDLTVLNHARYEHL-TRLWISNGIPGYISRV 1767
+APYL+ +GE+ + + G LN ARY +L + N IP + R+
Sbjct: 1811 YAAPYLSKYGETNED-YKFGTPVYLNRARYANLANEIVFGNMIPHIVFRL 1859
Score = 53.1 bits (126), Expect = 4e-06
Identities = 39/134 (29%), Positives = 58/134 (43%), Gaps = 7/134 (5%)
Query: 87 LSSKPWYKID-ENGGHSKFN-HAGRICGAKFRVGEPIYRCKECSFDDTCVLCVNCFNPKD 144
L+ + W ++ EN HS N H G C E IY C CS + +C CF+ +
Sbjct: 72 LNGRKWRTLEFENDHHSVGNMHIGTACTRLCFPSETIYYCFTCSTNPLYEICELCFDKEK 131
Query: 145 HVGHHVYTSICTEFNNGICDCGDKEAWN---HELNCKGAEDNGRLEDEFDDHDGKISKML 201
HV H + IC CGD A+N CK +N + + D+ + + +
Sbjct: 132 HVNHSYVAKVVMRPEGRICHCGDPFAFNDPSDAFKCKNELNNIPISN--DNSNVTDDENV 189
Query: 202 ESVLIELFDHFIDV 215
S+L + D IDV
Sbjct: 190 ISLLNYVLDFLIDV 203
>CE08535 [O] KOG1140 N-end rule pathway recognition component UBR1
Length = 1927
Score = 108 bits (269), Expect = 1e-22
Identities = 259/1352 (19%), Positives = 476/1352 (35%), Gaps = 250/1352 (18%)
Query: 108 GRICGAKFRVGEPIYRCKECSFDDTCVLCVNCFNPKDHVGHHVYTSICTEFNNGICDCGD 167
G+ICG F+ GE Y C +C+ D TCV+C+ CF H H + + +G CDCGD
Sbjct: 13 GQICGHVFKNGELTYTCLDCATDGTCVMCLQCFEVSIHKSHKY--KMHSSSGSGYCDCGD 70
Query: 168 KEAWNHELNCKGAEDNGRLEDEFDDHDGKISKMLESVLIELFDHFIDVFNQNIEPLTTIQ 227
+AW C E DD + + L L + + +++ Q
Sbjct: 71 ADAWTEGYACANHEKK-------DDEEAAV---LAPELKKRCEQLVEIILQ--------- 111
Query: 228 KPLIAKLRYFIQNGKYNEQADMLRRLAYRNQYMDEEESQQQTPSTSLDPLSTLKDYAILV 287
L + +++ E ++ P + + + Y ++
Sbjct: 112 --------------------FSLSMITHKDDLKLPEIFEKMKPEVT----NEAQQYLTVL 147
Query: 288 YNDEFHNYSQASAAIRQGGPDNKHIDLLTAKI-DSEGRSLLRCSA--------------- 331
YNDE H Y + K +L A I D EGRS ++ +
Sbjct: 148 YNDETHTYESVIKVLELYIHCTKDQAMLVATIVDREGRSAVKLGSKADCTKAKDDVQRKT 207
Query: 332 --DIASLMGGFFSVQSNGLSCTITQWYEYLHQEACKYSIMWINDCLNIPNSTFQSLFRNA 389
D S+ S + LS + + Q + W+N +++ F L R
Sbjct: 208 ARDPTSIRRS--SNHNLPLSVKVMDTTLFALQNFSISLLTWLNTQMDV----FPPL-REI 260
Query: 390 IGKVLCS-------KYEPFYQSIDMTSVVRDYFSDSYLSDD--PYLYA-----------D 429
+G++L S Y +S D V + L DD L+A D
Sbjct: 261 VGEILLSSKFALKKNYTRKMKSEDQRLVAGIIRNVMVLPDDEEEELFALDGRMDVDEMDD 320
Query: 430 HSVLGEGVKIPLGRHKSLDPGDISAISPILNKVIAEDHHE--------YTNSRLQYVLFL 481
+ GE +++ +D D I+ L V +H E T + L+ +L
Sbjct: 321 DDIGGEALQM------EIDADDEEEITAALAGV--SEHQESPGPSRDSSTFTMLENILLQ 372
Query: 482 ENRYWKKLRKIVQDLIIPTLASSAVHKPMFTDQLVEIFPHMTRSVTFMDREPQLTSLRES 541
+ + WK R I+ +++ T+ K F + + + D E ++ + S
Sbjct: 373 DTQMWKAGRSILHQMLMRTVFMIYDQKVRFAKAFMLHYNEIYEDFIKDDHEMDVSVVGLS 432
Query: 542 VVQLFTCPTTAYSIFHSGHFNYVIWSVI----DVFVDFSTMDEGTLV-WQRVQRSNPSK- 595
VQ T P+ A + VI I D FV + ++G + + RS P +
Sbjct: 433 -VQFMTVPSLARKLVAEDQAFSVISKAIRDQTDKFVKY--YNDGKIARFDFTSRSFPPEL 489
Query: 596 SYSISFKQGLYAVETLLSKITDPNLLLKPG---EFIMIVTLCKLFNGAWKIKRKEGEHVL 652
S+ + + + + +D N L G F + + G ++KR+ EH +
Sbjct: 490 RRSLHITRDMAYILNAVPSESDWNRELIDGFVQGFADFLLFLQHLQGMDEVKRQAVEHQV 549
Query: 653 REDQHFIPYLEYTTSVYSIIQTFDKVLQ-----QSKDHIDQRLLIGAINLLDS----FLG 703
E E+ T+ +++ D + ++ + + RL+I + L++ +
Sbjct: 550 WES-------EWETAFNILLRLKDAISMIIGWAETNEEVHNRLMIMCLELMNRMPPVYTK 602
Query: 704 HRNLSYKLY-----KDFEIIKFQISKERVSFMNPVHTLFSFLV---------------QH 743
+Y+L + I F + K S PV + + L H
Sbjct: 603 SEEDTYELTVTINGESCRISHFDVLKSSTSVHQPVVRIIAGLFSASNYTGFLLNRSNNSH 662
Query: 744 VPL-QVSIQVLSQSKDYLVISDFALRSVVLCSQIDIGFWVRNGMSVLHQ-SAYYKNNPEM 801
L Q I+ L KD + + +LR +VLC+Q + W RNG S+++Q Y+
Sbjct: 663 TSLNQERIKELINCKDETNLYELSLRVLVLCAQSNATLWRRNGFSLINQIHNYFSPLCRN 722
Query: 802 SSYSRDIQLNQLAFLIEKNDFQRVIYNMLDRWELLDWFDG-----------SVPSTETVY 850
+ RD+ + Q+ + + + I+++L R+ L W + P +E +
Sbjct: 723 EMFDRDVLMMQVGAALTPS--TKFIFHLLHRFRLFKWATSEFEQDKANEKPAKPESEDL- 779
Query: 851 DDKISSIIQQFVAFLYQILVERDFYKKFDTLEETQLYNIKNAIIYKLYAEPLSYTDLLND 910
+ I ++F+ L IL ER Y T Q+ K +I+ L +++ +
Sbjct: 780 SKTLVMIAEEFIQCLILILCERYTYGVGKTRPMDQM---KREVIHILCTGSHTFSHIQQK 836
Query: 911 IPDYLTESVSQFDTVLEEVSTYIEPKGLEDNGVFKLKKELYKRIDSLRLLNMGNDFEHSA 970
+ + + V+ + +P G F K+ ++ + +A
Sbjct: 837 MSHDINSKRLSLHEAVNLVADFRKPLA-TTAGQFHCKESSLPTYSPF-FMHYSKSDQSAA 894
Query: 971 TIVKSHLADSKEKRAKIIVKPQLLELDELDPCARELGSFTRTNXXXXXXXXXXXXXVSDS 1030
++ + EK + P L + + TN S
Sbjct: 895 EQSQARVRAKMEKSVRACAPP---ILPDFQTFFERIPEILTTNVLIHVVRLIIDRTARRS 951
Query: 1031 SFS---FTYELLHLIHAIFRDDEM------------VNGKDSLPEAYISKP---ICDLLL 1072
FS ++ L+LI ++E G SL E + KP IC +LL
Sbjct: 952 RFSSDRLFHKTLYLIGIALNEEEKNPSFGFTQRAEESIGLLSLLEGLVGKPESSICPILL 1011
Query: 1073 SIVDS-------------ESGSFSENVVATADYLLDNMIMKRPTAVLESLTECFGTKYIA 1119
+ E+ EN A ++ + + KR E +
Sbjct: 1012 EVTVEKYRKLIKARAGVPEAAPAPENKPAQSE---EEIKAKRAARAAEMRQKAMAKMSNM 1068
Query: 1120 DYKIRKANQGVNFEETEQERKRRLAKNRQQQIMNRFSRQQKKFMDKHEEYSAGNDEDVDM 1179
K K E+ E++ + + + + ++ + K F D+ G+D V +
Sbjct: 1069 QSKFMK-----KIEDEEKKDESQTPSEKSETVVKKDDYDNKHFFDEDVVKQVGHDFPVCI 1123
Query: 1180 DGEDLAGEL---NEFHCSLCHDDVSDDFFVIPIYQNYSPVFLSSNPTPMEIYKPWHGFDN 1236
EL C LC +D + P Q P+ ++ +++ H N
Sbjct: 1124 GANKWHAELVKPRTLTCILCQEDE----IIAP--QQGKPMVCAAFIQQSQLFT--HKNKN 1175
Query: 1237 NEHLATYNTDLFYKKKENGASQLMHESTQKVLVSCNHAVHYRCFKHYIDKKRYSTDL--- 1293
E + + + + + L + + +C+H++HY C++ + R L
Sbjct: 1176 GELMTASSGTISTRDLLTAPATLQYGVD---VSTCSHSMHYECYRSLAEANRSRESLRAR 1232
Query: 1294 ----------------FICPLCQTYCNSVIPV 1309
+ CPLC+ N+ IPV
Sbjct: 1233 QVGQHSHKMVDTENGEYQCPLCKRLSNAAIPV 1264
>Hs20555197 [O] KOG1140 N-end rule pathway recognition component UBR1
Length = 1242
Score = 100 bits (250), Expect = 2e-20
Identities = 152/671 (22%), Positives = 282/671 (41%), Gaps = 121/671 (18%)
Query: 716 EIIKFQISKERVSFMNPVHTLFSFLVQHVPLQVSIQVLSQSKDYLVISDFA--------L 767
E I++ +S+E+VS PV L + L HV L S +V + + L +S+ + L
Sbjct: 84 ETIRYCVSQEKVSIHLPVSRLLAGL--HVLLSKS-EVAYKFPELLPLSELSPPMLIEHPL 140
Query: 768 RSVVLCSQIDIGFWVRNGMSVLHQSAYYKN-NPEMSSYSRDIQLNQLAF-LIEKNDFQRV 825
R +VLC+Q+ G W RNG S+++Q YY N + +D+ + Q +++ N F +
Sbjct: 141 RCLVLCAQVHAGMWRRNGFSLVNQIYYYHNVKCRREMFDKDVVMLQTGVSMMDPNHFLMI 200
Query: 826 IYNMLDRWELLDWFD----GSVPSTETVYDDKI---SSIIQQFVAFLYQILVERDFYKKF 878
ML R+EL F G S+E + D + +++I++ + + ++ ER F
Sbjct: 201 ---MLSRFELYQIFSTPDYGKRFSSEITHKDVVQQNNTLIEEMLYLIIMLVGER-FSPGV 256
Query: 879 DTLEETQLYNIKNAIIYKLYAEPLSYTDLLNDIPDYLTESVSQFDTVLEEVSTYIEPKGL 938
+ T IK II++L +P+++++L+ +P+ + ++V+E V+ + +P GL
Sbjct: 257 GQVNATD--EIKREIIHQLSIKPMAHSELVKSLPEDENKETG-MESVIEAVAHFKKP-GL 312
Query: 939 EDNGVFKLKKELYKRIDSLRLLNMGNDFEHSATIVKSHLADSKEKRAKIIVKPQLLELDE 998
G+++LK E K +L + + A + L ++ R + P + L
Sbjct: 313 TGRGMYELKPECAKEF-NLYFYHFSRAEQSKAEEAQRKL--KRQNREDTALPPPV--LPP 367
Query: 999 LDPCARELGSFTRTNXXXXXXXXXXXXXVSDSSF----SFTYELLHLIHAIFRDD----E 1050
P L + +++ V + + S +LHLI +++ E
Sbjct: 368 FCPLFASLVNILQSDVMLCIMGTILQWAVEHNGYAWSESMLQRVLHLIGMALQEEKQHLE 427
Query: 1051 MVNGKDSLPEAY---ISKPICDLLLSIVDSESGSFSENVVA------TADYL-----LDN 1096
V + + + ISKP E+ S +++A A YL +
Sbjct: 428 NVTEEHVVTFTFTQKISKP----------GEAPKNSPSILAMLETLQNAPYLEVHKDMIR 477
Query: 1097 MIMKRPTAVLESLTECFGTKYIADYKIRKANQGVNFEET-------EQERKRRLAKNRQQ 1149
I+K AV + + E T +A+ +G EE+ E++RK +A+ R++
Sbjct: 478 WILKTFNAV-KKMRESSPTSPVAE------TEGTIMEESSRDKDKAERKRKAEIARLRRE 530
Query: 1150 QIMNRFSRQQKKFMDKHEEYSAGNDEDVDMDGEDLAGELNEFHCSLCHDDVSDDFFV--- 1206
+IM + S Q+ F+D+++E + +++D A L H V+ D +
Sbjct: 531 KIMAQMSEMQRHFIDENKELF---QQTLELDASTSA--------VLDHSPVASDMTLTAL 579
Query: 1207 ------IPIYQNYSPVFLSSNPTPMEIYK---PWHGFDNNEHLATYNTDLFYKKKENGAS 1257
+P + + L +++ F + + N F + E
Sbjct: 580 GPAQTQVPEQRQFVTCILCQEEQEVKVESRAMVLAAFVQRSTVLSKNRSKFIQDPEKYDP 639
Query: 1258 QLMHE--STQKVLVSCNHAVHYRCFKHYID-----------KKRYSTDL------FICPL 1298
MH S SC H +H C++ Y D + R T F+CPL
Sbjct: 640 LFMHPDLSCGTHTSSCGHIMHAHCWQRYFDSVQAKEQRRQQRLRLHTSYDVENGEFLCPL 699
Query: 1299 CQTYCNSVIPV 1309
C+ N+VIP+
Sbjct: 700 CECLSNTVIPL 710
>7293307 [O] KOG1140 N-end rule pathway recognition component UBR1
Length = 1829
Score = 90.1 bits (222), Expect = 3e-17
Identities = 122/513 (23%), Positives = 230/513 (44%), Gaps = 50/513 (9%)
Query: 475 LQYVLFLENRYWKKLRKIVQDLIIPTLASSAVHKPMFTDQLVEIFPHMTRSVTFMDREPQ 534
++++L + + WK R L+I + +K + + + + D +
Sbjct: 372 IRHILEYDVKLWKTARTCWHRLLISGMLMEYDNKMILAQEFSRRYATIVEDFISDDHDHA 431
Query: 535 LTSLRESVVQLFTCPTTAYSIF-HSGHFNYVIWSVIDVFVDFSTMDEGTLVWQRVQRSNP 593
+ + SV QLFT P+ A+ + H G F+ ++ + V ++ ++ TL ++
Sbjct: 432 FSIVSLSV-QLFTVPSIAHHLIAHEGIFDKLLHTFYHVAIEKFIRNK-TL---HFSKNIA 486
Query: 594 SKSYSISFKQGLYAVETLLSKITDPNLL---LKPGEFIMIVTLCKLFN---GAWKIKRKE 647
S ++ LY + LLS P++L L+ G L ++ N G + R+
Sbjct: 487 SLTFFKRANYILYDLRYLLS--LKPDVLSNDLRNGFLEGCRALMRVLNVMQGMESMTRQT 544
Query: 648 GEHVLREDQH---FIPYLEYTTSVYSIIQ--TFDKVLQQSKDHIDQRLLIGAINLLDSFL 702
G+H+ E + F +++ T++ +I + D L + + R L+ +SF+
Sbjct: 545 GQHMDYEPEWECAFNLHIKLATTISQVIDWASGDVKLLRKLYKMTMRALVS-----NSFI 599
Query: 703 --GHRNLSYKLYKDF--EIIKFQISKERVSFMNPVHTLFSFLVQHVP--------LQVSI 750
G + + K D + + IS + VS P+ F+ + H+ LQ
Sbjct: 600 VGGEKVMQPKKVADHVANCLVYDISVQPVSIHLPLSRFFAGIYLHLGAHDLTYDGLQTET 659
Query: 751 QVLSQSKDYLVISDFALRSVVLCSQIDIGFWVRNGMSVLHQSAYYKN-NPEMSSYSRDIQ 809
+ LS I + L + + +Q+ G W RNG ++LHQ +Y+N + RDI
Sbjct: 660 EALSIKLTPREIIEPVLCTQAMIAQVGAGLWRRNGYTLLHQLYFYRNVRCRVEMLDRDIA 719
Query: 810 LNQL-AFLIEKNDFQRVIYNMLDRWELLDWFD---GSVPSTETVYDDKI--SSIIQQFVA 863
Q+ A L+E N+F + ++L+R+ + W S+ S + DD I +SI +F+
Sbjct: 720 CLQIGASLMESNEF---LIHVLNRFNTIPWLQENYWSLLSGNEMNDDIIREASIFDEFLE 776
Query: 864 FLYQILVERDFYKKFDTLEETQLYNIKNAIIYKLYAEPLSYTDLLNDIPDYLT-ESVSQF 922
L I+ ER EE +L + II L +P S+++L +PD + S + F
Sbjct: 777 LLIVIIGERWMPGVSMVTEEDRL---RKEIIQLLCIKPYSHSELSRALPDGNSGNSDNVF 833
Query: 923 DTVLEEVSTYIEPKGLEDNGVFKLKKELYKRID 955
+ V+ V+ + +P G + GV++LK+ L K +
Sbjct: 834 EEVINTVAVFKKPVGADSKGVYELKEHLLKEFN 866
Score = 77.4 bits (189), Expect = 2e-13
Identities = 34/69 (49%), Positives = 39/69 (56%), Gaps = 2/69 (2%)
Query: 110 ICGAKFRVGEPIYRCKECSFDDTCVLCVNCFNPKDHVGHHVYTSICTEFNNGICDCGDKE 169
+CG F+ GEP Y C+EC D TCVLCVNCF H H S T G CDCGD E
Sbjct: 113 VCGKVFKNGEPTYSCRECGVDPTCVLCVNCFKRSAHRFHKYKMS--TSGGGGCCDCGDDE 170
Query: 170 AWNHELNCK 178
AW + C+
Sbjct: 171 AWKKDQYCE 179
>SPBC19C7.02 [O] KOG1140 N-end rule pathway recognition component UBR1
Length = 271
Score = 82.4 bits (202), Expect = 7e-15
Identities = 54/193 (27%), Positives = 89/193 (45%), Gaps = 37/193 (19%)
Query: 111 CGAKFRVGEPIYRCKECSFDDTCVLCVNCFNPKDHVGHHVYTSICTEFNNGICDCGDKEA 170
CG FR GE YRCK CS D LCV CF H H ++ + + G CDCG+ A
Sbjct: 96 CGHIFRKGEVFYRCKTCSVDSNSALCVKCFRATSHKDHETSFTV-SAGSGGCCDCGNAAA 154
Query: 171 WNHELNCK---GAEDNGRLEDEFDDHDGKISKMLESVLIELFDHFIDVFN---QNIEPLT 224
W +++CK ED D D+ K+ +++ + + D +DVF+ +N++ +
Sbjct: 155 WIGDVSCKIHSHEEDATISNDMIDEIPEKLENSIQTTIDCVLDFVLDVFSCSPENLKKMP 214
Query: 225 TIQKPLIAKLRYFIQNGKYNEQADMLRRLAYRNQYMDEEESQQQTPSTSLDPLSTLKDYA 284
T++ L Q + RL+ N+Y D ++S Y+
Sbjct: 215 TLESIL---------------QDEKTSRLS-ENKYGDIDDSCNM--------------YS 244
Query: 285 ILVYNDEFHNYSQ 297
++++NDE H++ Q
Sbjct: 245 LVLWNDEKHSFKQ 257
>At5g02300 [O] KOG1140 N-end rule pathway recognition component UBR1
Length = 1225
Score = 73.6 bits (179), Expect = 3e-12
Identities = 115/551 (20%), Positives = 201/551 (35%), Gaps = 88/551 (15%)
Query: 714 DFEIIKFQISKERVSFMNPVHTLFSFLVQHV------------PLQVSIQVLSQSKDYLV 761
D+ I + +S + +S P+H L S L+Q + +S ++ V
Sbjct: 681 DWPDIHYDVSSQAISVHLPLHRLLSLLIQKALRICYGESASYNGVSISHEIPHADFFSSV 740
Query: 762 ISDF------------ALRSVVLCSQIDIGFWVRNGMSVLHQSAYYKNNPEMSSYSRDIQ 809
I DF L+ V C+Q+ G W +NG S L + + E+ D+
Sbjct: 741 IGDFHPCGFSALVMEHVLQIRVFCAQVIAGMWKKNGDSALVSCEWSEQGLEL-----DLF 795
Query: 810 LNQLAFLIEKNDFQRVIYNMLDRWELLDWFDGSVPSTETVYDDKISSIIQQFVAFLYQIL 869
L Q + D + +L R+ L + + P Y + ++ + + L QIL
Sbjct: 796 LLQCCAALAPAD--SYVDKLLSRFGLSSYLSLN-PDITNEYVPIV--LLLEMLGLLIQIL 850
Query: 870 VERDFYKKFDTLEETQLYNIKNAIIYKLYAEPLSYTDLLNDIPDYLTESVSQFDTVLEEV 929
ER F T E +++ II+KL +++ L+ +P L++S + VL++V
Sbjct: 851 QERRFC-GLSTAE-----SLRREIIFKLATGDFTHSQLVKSLPRDLSKS-DELQEVLDDV 903
Query: 930 STYIEPKGLEDNGVFKLKKELYKRIDSLRLLNMGNDFEHSATIVKSHL---ADSKEKRAK 986
S Y P G+ + G + L+ +K +D D + + + A + +
Sbjct: 904 SVYCNPSGM-NQGKYSLQSSCWKELDLYHPRWQSRDLQSAEERFSRYCGVSALTTQLPRW 962
Query: 987 IIVKPQLLELDELDPCARELGSFTRTNXXXXXXXXXXXXXVSDSSFSFTYELLHLIHAIF 1046
++ P L L + C + D +LL L I
Sbjct: 963 RMIYPPLKGLARIGTCKATFQIISSALYYALQSGTSVKSRAPDGVLITALQLLSLSLDIC 1022
Query: 1047 RDDEMVNGKDSLPEAYI------------------SKPICDLLLSIVDSESG----SFSE 1084
N +D E I + + LL+S++ + G F E
Sbjct: 1023 TQQRQSNSQDCCLENSIPILELAGLEIIGIAQGTEKESLLSLLVSLMKTRMGDGRHQFPE 1082
Query: 1085 NVVATADYLLDNMIMKRPT--AVLESLTECFGTKYIADYKIRKANQGVNFEETEQERKRR 1142
+ N++ K +V +L + + + K G T E+++
Sbjct: 1083 PGSCNISSWIGNLLKKFSAIDSVCMNLLQSLAPEVVGQSGFDKVMSG----STSDEKRKA 1138
Query: 1143 LAKNRQQQIMNRFSRQQKKFM----------DKHEEYSAGNDEDVDMDGEDLAGELNEFH 1192
AK RQ IM + +Q KF+ D E+ +D ++ D E E+
Sbjct: 1139 KAKERQAAIMAKMKAEQSKFLSTLSSSMDDDDPRSEFET-SDSVMEHDSEIAVREV---- 1193
Query: 1193 CSLCHDDVSDD 1203
CSLCHD S D
Sbjct: 1194 CSLCHDPDSKD 1204
Score = 63.5 bits (153), Expect = 3e-09
Identities = 34/91 (37%), Positives = 46/91 (50%), Gaps = 6/91 (6%)
Query: 110 ICGAKFRVGEPIYRCKECSFDDTCVLCVNCFNPKDHVGHHVYTSICTEFNNGICDCGDKE 169
+CG+ + + YRC+ C D TC +CV CF DH H Y+ I T G CDCGD+
Sbjct: 120 VCGSVWGQNDIAYRCRTCENDPTCAICVPCFQNGDH-NSHDYSIIYT--GGGCCDCGDET 176
Query: 170 AWNHELNC---KGAEDNGRLEDEFDDHDGKI 197
AW + C KG+E L + + G I
Sbjct: 177 AWKPDGFCSNHKGSEQIRPLSENLANSVGPI 207
>Hs18597977 [O] KOG1140 N-end rule pathway recognition component UBR1
Length = 717
Score = 70.1 bits (170), Expect = 3e-11
Identities = 97/459 (21%), Positives = 206/459 (44%), Gaps = 44/459 (9%)
Query: 478 VLFLENRYWKKLRKIVQDLIIPTLASSAVHKPMFTDQLVEIFPHMTRSVTFMDREPQLTS 537
++ + + +K RKI+ +LI + +K +F + V+ + + + D + + S
Sbjct: 279 LMLWDAKLYKGARKILHELIFSSFFMEMEYKKLFAMEFVKYYKQLQKEYISDDHDRSI-S 337
Query: 538 LRESVVQLFTCPTTAYSIFHSGHFNYVIW-SVIDVFVDFSTMDEGTLVWQRVQRSNPSKS 596
+ VQ+FT PT A + + VI ++++V ++ + +Q + +
Sbjct: 338 ITALSVQMFTVPTLARHLIEEQNVISVITETLLEVLPEYLDRNN-KFNFQGYSQDKLGRV 396
Query: 597 YSI--SFKQGLYAVETLLSKITDPNLLLKPGEFIMIVTLCKLFNGAWKIKRKEGEHVLRE 654
Y++ K L + T+ ++ L F+ I+T + G +I+R+ G+H+
Sbjct: 397 YAVICDLKYILISKPTIWTERLRMQFLEGFRSFLKILTCMQ---GMEEIRRQVGQHI-EV 452
Query: 655 DQHFIPYLEYTTSVYSIIQTFDKVLQQSKDHIDQRLLIGA--------INLLDSFLGH-R 705
D + + + +I+ F Q D+ LL+ A + SF+ +
Sbjct: 453 DPDWEAAIAIQMQLKNILLMF-----QEWCACDEELLLVAYKECHKAVMRCSTSFISSSK 507
Query: 706 NLSYKLYKDFEIIKFQISKERVSFMNPVHTLFSFLVQHVPLQVSIQVLSQSKDYLVISDF 765
+ E +++S++ VS P+ + L HV L + +S+ +++ DF
Sbjct: 508 TVVQSCGHSLETKSYRVSEDLVSIHLPLSRTLAGL--HVRLS-RLGAVSRLHEFVSFEDF 564
Query: 766 A--------LRSVVLCSQIDIGFWVRNGMSVLHQSAYYKN-NPEMSSYSRDIQLNQL-AF 815
LR +VL +Q+ W RNG+S++ Q YY++ Y +DI + Q+ A
Sbjct: 565 QVEVLVEYPLRCLVLVAQVVAEMWRRNGLSLISQVFYYQDVKCREEMYDKDIIMLQIGAS 624
Query: 816 LIEKNDFQRVIYNMLDRWELLDWFDGSVPSTETVYDDKISSIIQQFVAFLYQILVERDFY 875
L++ N F ++ L R+EL + F+ ++ + + + +++I++ + L I+ ER
Sbjct: 625 LMDPNKFLLLV---LQRYELAEAFNKTISTKDQDLIKQYNTLIEEMLQVLIYIVGERYVP 681
Query: 876 KKFD-TLEETQLYNIKNAIIYKLYAEPLSYTDLLNDIPD 913
+ T EE + II+ L EP+ ++ + ++P+
Sbjct: 682 GVGNVTKEEVTM----REIIHLLCIEPMPHSAIAKNLPE 716
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.320 0.137 0.405
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 121,118,660
Number of Sequences: 60738
Number of extensions: 5586622
Number of successful extensions: 16414
Number of sequences better than 1.0e-05: 9
Number of HSP's better than 0.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 16348
Number of HSP's gapped (non-prelim): 37
length of query: 1945
length of database: 30,389,216
effective HSP length: 121
effective length of query: 1824
effective length of database: 23,039,918
effective search space: 42024810432
effective search space used: 42024810432
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)