ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI4063 good O KOG1140 Posttranslational modification, protein turnover, chaperones N-end rule pathway, recognition component UBR1
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI4063 1417215 1422341 1709
(1709 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YLR024c [O] KOG1140 N-end rule pathway recognition component UBR1 1061 0.0
YGR184c [O] KOG1140 N-end rule pathway recognition component UBR1 136 3e-31
7293307 [O] KOG1140 N-end rule pathway recognition component UBR1 109 3e-23
SPAC15A10.11 [O] KOG1140 N-end rule pathway recognition componen... 107 2e-22
Hs20555197 [O] KOG1140 N-end rule pathway recognition component ... 91 1e-17
At5g02300 [O] KOG1140 N-end rule pathway recognition component UBR1 58 1e-07
CE08535 [O] KOG1140 N-end rule pathway recognition component UBR1 57 3e-07
Hs18597977 [O] KOG1140 N-end rule pathway recognition component ... 55 1e-06
Hs22044520 [O] KOG1139 Predicted ubiquitin-protein ligase of the... 52 8e-06
>YLR024c [O] KOG1140 N-end rule pathway recognition component UBR1
Length = 1872
Score = 1061 bits (2744), Expect = 0.0
Identities = 577/1486 (38%), Positives = 860/1486 (57%), Gaps = 129/1486 (8%)
Query: 4 SVRCLRDFLVHFAHFCRYRYNDMCSFYLWKVLLTCMNHCNEEINWEDLTHVFGLNQWEMG 63
S+ +RDFL + Y++ S+ LWK L + H + +INW L + WE
Sbjct: 7 SITNIRDFLTELPKLAKCEYSETTSYLLWKTLNLRLKHSDNDINWRSLVSILNSEAWENE 66
Query: 64 DFGKIKLRSNWRESLIPKRKH---NDHRGSQCSKQCHGTETVYYCFDCTKNPLYEICEDC 120
+ I WR H N H G+ C++ C +ET+YYCF C+ NPLYEICE C
Sbjct: 67 KYRDILNGRKWRTLEFENDHHSVGNMHIGTACTRLCFPSETIYYCFTCSTNPLYEICELC 126
Query: 121 FDESQHIGHRYTSRVVTRPEGKVCHCGDISSYNDPKKAFQCRIQSNNADIDVTNLQLYND 180
FD+ +H+ H Y ++VV RPEG++CHCGD ++NDP AF+C+ + NN I N + +D
Sbjct: 127 FDKEKHVNHSYVAKVVMRPEGRICHCGDPFAFNDPSDAFKCKNELNNIPISNDNSNVTDD 186
Query: 181 M-WISTFSQVLDFIIDCCFAWMDGDEKIKHEAVESI---PIKDSVG-------------N 223
IS + VLDF+ID ++ + E E S P ++S+ N
Sbjct: 187 ENVISLLNYVLDFLIDVTVSYKEEAEAHSSERKASSLMHPNQNSITDDIMEKHECEPLVN 246
Query: 224 VESF--------------SQKYVLVLYQHECNIHVQDVARKISRALKKDISFGTFVLSQF 269
E+F ++ + + + ECN+H D+A I+R L + + +
Sbjct: 247 DENFVFFDNNWSNTRKEAHMEWAIQIEEEECNVHYMDLASTITRILNTPVEYAISITKAL 306
Query: 270 DQDEHFTVIAESTNKAFMLRLKQELELQDIPTHLMNESNVFKRYMISELVRWLHHFAVHN 329
+ + +S N + ++ +E + ++I H+ ++FKR + +L WL+
Sbjct: 307 EDSHDVVTVLQSENFFEIDQIAKEFQKENIVVHVRKADDIFKRKLTDDLTDWLYSLCFKA 366
Query: 330 PSVLSGKLSLRLAYMDQYVSNL--LAVKPF-------KINILGNFIVPHQKHNSFPWIKP 380
+ L K +LR++ +D + S+ + V P KIN+LG F++ ++ + W KP
Sbjct: 367 ATSLQNKYALRISMLDVWYSHFSKMRVSPTNTNPDFSKINLLGGFLISNEDSDE-SWFKP 425
Query: 381 WNFQSNSDETHDPNITNVMLIYDQKIRETDTPNTACRYLPLSGSRFQYFITECLTTFSQF 440
W+ ++ DE I+ ++ Y++++ +PNT + GSRFQY I + S+
Sbjct: 426 WSLENIEDE----RISKILTNYNERLIRAHSPNTVSHFYNFYGSRFQYIIINSINILSKK 481
Query: 441 TRMRLLEVFGSIFSVRDDSKKCLAAQYLDVYCNILYRTIVSDASGYKLTLMSTLSQYIFP 500
++ ++L++ S+FS+RD+S+K LAAQY+DVY ++LY + SDA ++TLMS L QY F
Sbjct: 482 SKFKMLKIMASLFSLRDESRKFLAAQYIDVYLSVLYDAVASDAKECQVTLMSILGQYTFQ 541
Query: 501 SPSTANMIINAGFIERCLTFSYSIMSSDSEIVPNSPPIPLSSEFKLPDTVIKNKKAVICF 560
PS ANM I++GFIER + F++++M+ + E + + PI L + FKLP I+N++ +ICF
Sbjct: 542 DPSIANMTISSGFIERTIRFAFTLMAFNPEDLMSYLPISLYNGFKLPTETIRNRRTIICF 601
Query: 561 KDIYQAMCTNTKPASVFANESLTNAMRECFFSFNKILPLKRETSEHVQYENXXXXXXXXX 620
KD+ M NT P + +NE++ NA+ E F F+ +LPLKRET EHV+ EN
Sbjct: 602 KDLCTIMSANTVPEELLSNEAIFNAIIESFSEFSNVLPLKRETKEHVEVENFDFSAFYFF 661
Query: 621 XXXILIMVDGFLRNISLVLDPIKRKQLVSTLLTTSIDKHLSSLDKFRPSI-PGNTS---- 675
ILIM DG+ R+ISLV D RKQ+V LL + + SL R +I P N S
Sbjct: 662 FSSILIMTDGYTRSISLVKDAAFRKQIVLKLLDVAQTREFESLTNSRKAISPDNASTNEN 721
Query: 676 -------NTFKTTVCNVQTRIFNFKVGSETQNFFNPISYYIKFILQWSQCGRYEPLPETL 728
+T + T+CN NF+VG TQ FFNP+SY KF++QWSQCGRYEP+P +L
Sbjct: 722 DSNKATLSTVRETICNYVAETINFQVGVNTQYFFNPMSYLFKFVIQWSQCGRYEPIPASL 781
Query: 729 KDYFNFKEFFKSPTECLWIAEQALCTLVMISQIDVGFWVRNGSPIQHQLKMYTKYSMREF 788
+Y N E F+ + L+I+E AL TLV+I QI+VGFWVRNG+PI HQ +MYTKYSMREF
Sbjct: 782 TNYINLFEVFQDKQKALYISESALSTLVLIGQINVGFWVRNGTPITHQARMYTKYSMREF 841
Query: 789 TYFSDFFLVQFSMCYADPHDFMVNFLTRWGLKYWAEGIPIGDYPEESLTIAMTEQCFLTL 848
TY SD F VQFSM +P + MV +L+RWGLK+WA G+P+ DYP+ T+A+ +C L L
Sbjct: 842 TYISDIFNVQFSMAMCNPDELMVTYLSRWGLKHWANGVPMYDYPDTETTVAVVNECILLL 901
Query: 849 IRLMTETRALCASTSVEGFESTMKSEIIHSLCFRKCSYSSLVEAIPEHVTKHPAFDLYLN 908
I+L+TE R+L +S EGFE T KSEIIH+LCF CSY+ +V IPEH+TKHP+FD+YL
Sbjct: 902 IQLLTEVRSLVMKSSKEGFERTFKSEIIHALCFDTCSYAQIVNCIPEHITKHPSFDIYLE 961
Query: 909 QYSDYHEPTGNFDTGTYSLKKQYRKQIDPFFVGFSSNKRYEATLLVRERMKETYGVSFND 968
+Y++Y P D G + LK++Y+ +IDP+++G SS++RY+ +R M + + D
Sbjct: 962 KYANYTSPVSLTDNGIFVLKEKYKDEIDPYYIGLSSSRRYDVEKNIRLNMANLKKMKYED 1021
Query: 969 TFVQASSIQDQLRNTQYQNLYQITSTDIFGVFVKNTLVHIMKMKLESLLGKVLHLIHLCV 1028
TFV A ++D L+NT + LY I+S + FG+F+KNTL HI+K ++LL +V+HLIHLCV
Sbjct: 1022 TFVPAKKVKDLLKNTLFSGLYSISSVNTFGLFLKNTLDHIIKYDYDNLLPRVVHLIHLCV 1081
Query: 1029 VNNLADFERIFWHEYHLDESENGFYHSIGSLLYNFLSSDDFNVENGKIREIFRFLKDRAP 1088
VNNL +F I WHEY + ++E YHSIGS+LY L D+F+ +GKIREIFR+L + AP
Sbjct: 1082 VNNLNEFMGILWHEYAIVDTEFCHYHSIGSILYYCLLKDNFSESHGKIREIFRYLMETAP 1141
Query: 1089 HINVDDYLSEQTPNYDPRILF--TDISESENEEYIKKKMLAKSRREKLMQKLAKQQKEFM 1146
H+NV+ YL EQT +Y P IL+ + +++E+ +KK LA+ R++KLM+KLA+QQ +FM
Sbjct: 1142 HVNVNSYLREQTTSYTPGILWPTKEDKSHKDKEFERKKHLARLRKKKLMKKLAQQQMKFM 1201
Query: 1147 DNNNVSAEDISSQGT----------NLDNSA--IGICWTYPEDDCVFCKMPKDYDVLSYF 1194
+NN+V DIS+ T N +NS+ I C +DDCVFCKMPKD DV YF
Sbjct: 1202 ENNSVDTSDISTPRTTSPSLSPTRINAENSSNTINSCC---DDDCVFCKMPKDDDVFVYF 1258
Query: 1195 VFVERNV----------VSIN----LASDDKTKDVEFQ-----------------PVLTT 1223
+ ERN+ +N L S +TKD Q PVL
Sbjct: 1259 SYQERNICDHGIDFTNPTDVNRINSLFSGKQTKDSAIQENPQDDDGTRLKFTSCEPVLRA 1318
Query: 1224 CGHCAHFGCLLSHMKSLRKSLGQITKNIRDTFGXXXXXXXXXXXXVNAFIP--------- 1274
CGH +H CL HMKS+R Q TKNI ++G N+F+P
Sbjct: 1319 CGHGSHTKCLSGHMKSIRGIQNQTTKNIPLSYGSGLIYCPVCNSLSNSFLPKTNDIDKRT 1378
Query: 1275 -------LLKGTQYCADYNSKSLVTRHSLALITELSGLKF-SLQNGFTAGYTLFANTISN 1326
+ K ++ + + S + + ++ +L G K ++++ + ++F NTISN
Sbjct: 1379 SSQFFMCIEKRSEAEENLDPMSSICIKAAMILGDLQGKKVTTIEDAYKVVNSVFINTISN 1438
Query: 1327 LELVLRD--ESNKFV-INKLTSRQITSLRLLDDLISFGLEKKMISA 1369
EL LR + K V + +++S+ I +L L+ +L SF + KK +++
Sbjct: 1439 TELRLRSHKKEGKIVNMERISSQCILTLHLVCELKSF-IYKKFVNS 1483
Score = 144 bits (363), Expect = 1e-33
Identities = 70/167 (41%), Positives = 99/167 (58%), Gaps = 3/167 (1%)
Query: 1543 SIVTRKPKIPVSSPFIDLPRVISYMSKQTDSEINLRFSAFKEDIAICMFCGLSCILQKVS 1602
+I TR P I+LP +S S D N K +IA+C+ CG C +QK
Sbjct: 1709 NINTRAYPSPEHIQLIELPLNLSKFSLDNDEISN---KCDKYEIAVCLLCGQKCHIQKSI 1765
Query: 1603 LLHFSRIGQCTNHYYNECKCKAPFGCFFILKSNIIYLSYGSRGSFYQTPYVNKHGETDED 1662
L G+CT+H N C+ + +G F + +N IYLSYG RG+FY PY++K+GET+ED
Sbjct: 1766 ALQGYLQGECTDHMRNGCEITSAYGVFLMTGTNAIYLSYGKRGTFYAAPYLSKYGETNED 1825
Query: 1663 YKLGTPVFFNKARYQHFIQDIMLSGKIPHLINRANDKTVDVGGWESM 1709
YK GTPV+ N+ARY + +I+ IPH++ R D + D+GGWE+M
Sbjct: 1826 YKFGTPVYLNRARYANLANEIVFGNMIPHIVFRLTDGSADLGGWETM 1872
>YGR184c [O] KOG1140 N-end rule pathway recognition component UBR1
Length = 1950
Score = 136 bits (342), Expect = 3e-31
Identities = 259/1213 (21%), Positives = 474/1213 (38%), Gaps = 185/1213 (15%)
Query: 593 FNKILPLKRETSEHVQYENXXXXXXXXXXXXILIMVDGFLRNISLVLDPIKRKQLVSTLL 652
FN +KR+ EHV +E+ +L + + I+ + VS
Sbjct: 665 FNGAWKIKRKEGEHVLHEDQNFIS--------------YLEYTTSIYSIIQTAEKVSEKS 710
Query: 653 TTSIDKHLSSLDKFR--PSIPGNTSNTFKTTVCNVQTRIFNFKVGSETQNFFNPISYYIK 710
SID L L+ R S GN S T+K + + + F V E F NP+ +
Sbjct: 711 KDSIDSKLF-LNAIRIISSFLGNRSLTYKLIYDSHE--VIKFSVSHERVAFMNPLQTMLS 767
Query: 711 FILQWSQCGRYEPLPETLKDYFNFKEFFKSPTECLWIAEQALCTLVMISQIDVGFWVRNG 770
F+++ +LKD + E + ++ L I++ +L ++V+ SQIDVGFWVRNG
Sbjct: 768 FLIE----------KVSLKDAY---EALEDCSDFLKISDFSLRSVVLCSQIDVGFWVRNG 814
Query: 771 SPIQHQLKMYTKYSMREFTYFSDFFLVQFSMCYA--DPHDFMVNFLTRWGLKYWAEGIPI 828
+ HQ Y K + +Y D L Q ++ + D + N L RW L W G
Sbjct: 815 MSVLHQASYY-KNNPELGSYSRDIHLNQLAILWERDDIPRIIYNILDRWELLDWFTGEVD 873
Query: 829 GDYPEESLTIAMTEQCFLTLI-RLMTETRALCASTSVEGFE-STMKSEIIHSLCFRKCSY 886
+ I+ Q F+ I +++TE + +S++ +K+ II++L + SY
Sbjct: 874 YQHTVYEDKISFIIQQFIAFIYQILTERQYFKTFSSLKDRRMDQIKNSIIYNLYMKPLSY 933
Query: 887 SSLVEAIPEHVTKHPA-FDLYLNQYSDYHEPTGNFDTGTYSLKKQYRKQIDPFFVGFSSN 945
S L+ ++P+++T+ FD L + S + EP G D G + LK ++DP + N
Sbjct: 934 SKLLRSVPDYLTEDTTEFDEALEEVSVFVEPKGLADNGVFKLKASLYAKVDPLKLLNLEN 993
Query: 946 KRYEATLLVRERMKETYGVSFNDTFVQASSIQDQLRNTQYQNLYQITSTDIFGVFVKNTL 1005
+ + +++ + + + SI+ ++ NL T +F V L
Sbjct: 994 EFESSATIIKSHLAKDKDEIAKVVLIPQVSIKQLDKDA--LNLGAFTRNTVFAKVVYKLL 1051
Query: 1006 VHIMKMKLESLLGKVLHLIHLCVVNNLADFERIFWHEYHLDESENGFYHSIGSLLYNFLS 1065
+ M+ + L ++LHL+H ++ + E +L + SI + + S
Sbjct: 1052 QVCLDMEDSTFLNELLHLVHGIFRDDELINGKDSIPEAYLSKPICNLLLSIANAKSDVFS 1111
Query: 1066 SD-----DFNVEN---GKIREIFRFLKDRAPHINVDDYLSEQTPNYDPRILFTDISESEN 1117
D+ +E K E+F L + V+DY ++ ++ E+E
Sbjct: 1112 ESIVRKADYLLEKMIMKKPNELFESLIASFGNQYVNDYKDKKLRQ------GVNLQETEK 1165
Query: 1118 EEYIKKKMLAKSRREKLMQKLAKQQKEFMDNNNVSAEDISSQGTNLDNSAIGICWTYPED 1177
E +K+ LAK + +L+ K QQ +FM + + Q ++D + Y +
Sbjct: 1166 E---RKRRLAKKHQARLLAKFNNQQTKFMKEHE---SEFDEQDNDVDMVGEKV---YESE 1216
Query: 1178 D--CVFCK--MPKDYDVLSYF-----VFVERNVVSIN---------LASDDKTKDVE--- 1216
D C C+ D+ V+ + +F N+ + N D+K ++
Sbjct: 1217 DFTCALCQDSSSTDFFVIPAYHDHSPIFRPGNIFNPNEFMPMWDGFYNDDEKQAYIDDDV 1276
Query: 1217 -----------FQPVLTTCGHCAHFGCLLSHMKSLRKSLGQITKNIRDTFGX-XXXXXXX 1264
+ V +C H H C +++ R S + TF
Sbjct: 1277 LEALKENGSCGSRKVFVSCNHHIHHNCFKRYVQKKRFSSNAFICPLCQTFSNCTLPLCQT 1336
Query: 1265 XXXXVNAFIPLLKGTQYCADYNSKSL--VTRHSLALITELSGLKFSLQNGFTAGY----- 1317
+ + ++ D S+ T + I + L S GF
Sbjct: 1337 SKANTGLSLDMFLESELSLDTLSRLFKPFTEENYRTINSIFSLMISQCQGFDKAVRKRAN 1396
Query: 1318 -----------TLFANTISNLELVLRDESNKFVINKLTSRQITSLRLLDDLISFGLEKKM 1366
+ANTIS LE+ R E + I+ SR+ L + L+ L +
Sbjct: 1397 FSHKDVSLILSVHWANTISMLEIASRLE-KPYSISFFRSREQKYKTLKNILVCIMLFTFV 1455
Query: 1367 ISASGPHSDDIFMSLCSSMHMLSDDEHILHLLKTKLIEELSLRINEVAALSY-------- 1418
I G S + + + ++ +++++ L +SLR AL+
Sbjct: 1456 I---GKPSMEFEPYPQQPDTVWNQNQLFQYIVRSALFSPVSLRQTVTEALTTFSRQFLRD 1512
Query: 1419 ----QNDIPRQKKSFSIPYR--DV--ISQIIISRIHTTSVINQTEILKAEGIFRGNEMIF 1470
+D + K ++ + DV +S+ ++ + T S + + E L +E I +
Sbjct: 1513 FLQGLSDAEQVTKLYAKASKIGDVLKVSEQMLFALRTISDV-RMEGLDSESIIYD---LA 1568
Query: 1471 IDFIMVQFLIFLRKVCI---ALHSKYISADKAVISGKGYNELETMIDFCNLPPFIELLQE 1527
F++ L +R+ + LH ++ + G+ E+E ++F + F+ +
Sbjct: 1569 YTFLLKSLLPTIRRCLVFIKVLHELVKDSENETLVINGH-EVEEELEFEDTAEFVNKALK 1627
Query: 1528 LFCKNSSDPEGSGKCSIVTRKPKIPVSSPF--------------IDLPRVISYMSKQTDS 1573
+ + S ++T + I VS P+ IDL + ++ Q+
Sbjct: 1628 MITEKES------LVDLLTTQESI-VSHPYLENIPYEYCGIIKLIDLSKYLNTYVTQS-K 1679
Query: 1574 EINLRFSAFKE--------DIAICMFCGLSCILQKVSLLHFSRIGQCTNHYYNECKCKAP 1625
EI LR + D IC+ CG+ L+ + + T H C P
Sbjct: 1680 EIKLREERSQHMKNADNRLDFKICLTCGVKVHLR-------ADRHEMTKHLNK--NCFKP 1730
Query: 1626 FGCFFILKSN--IIYLSYGSRGSFYQTPYVNKHGETDED-YKLGTPVFFNKARYQHFIQD 1682
FG F + S+ ++L+ F PY+N HGE + + G N RY+H +
Sbjct: 1731 FGAFLMPNSSEVCLHLTQPPSNIFISAPYLNSHGEVGRNAMRRGDLTTLNLKRYEH-LNR 1789
Query: 1683 IMLSGKIPHLINR 1695
+ ++ +IP I+R
Sbjct: 1790 LWINNEIPGYISR 1802
Score = 54.3 bits (129), Expect = 2e-06
Identities = 30/122 (24%), Positives = 51/122 (41%), Gaps = 16/122 (13%)
Query: 87 HRGSQCSKQCHGTETVYYCFDCTKNPLYEICEDCFDESQHIGHRYTSRVVTRPEGKVCHC 146
H G C ++ E +Y C +C + +C CF+ H+ H + + T +C C
Sbjct: 118 HTGRNCGRKFKIGEPLYRCHECGCDDTCVLCIHCFNPKDHVNHHVCTDICTEFTSGICDC 177
Query: 147 GDISSYNDPKKAFQCRIQSNNADID---VTNLQL-YNDMWIST---------FSQVLDFI 193
GD ++N P C+ + DI TN + D+W + ++V D+
Sbjct: 178 GDEEAWNSP---LHCKAEEQENDISEDPATNADIKEEDVWNDSVNIALVELVLAEVFDYF 234
Query: 194 ID 195
ID
Sbjct: 235 ID 236
>7293307 [O] KOG1140 N-end rule pathway recognition component UBR1
Length = 1829
Score = 109 bits (273), Expect = 3e-23
Identities = 222/1128 (19%), Positives = 422/1128 (36%), Gaps = 169/1128 (14%)
Query: 77 SLIPKRKHNDHRGSQCSKQCHGTETVYYCFDCTKNPLYEICEDCFDESQHIGHRYTSRVV 136
S + K + + + C K E Y C +C +P +C +CF S H H+Y ++
Sbjct: 99 SALEKLRLEGNTATVCGKVFKNGEPTYSCRECGVDPTCVLCVNCFKRSAHRFHKY--KMS 156
Query: 137 TRPEGKVCHCGDISSYNDPKKAFQCRIQSNNADIDVTNLQLYNDMWISTFSQVLDFIIDC 196
T G C CGD ++ KK C + N + + ++ D + I+
Sbjct: 157 TSGGGGCCDCGDDEAW---KKDQYCELHLANRKNPLES-KILTDAVLERVEICFGAILAF 212
Query: 197 CFAWMDGDEKIKHEAVESIPIKDSVGNVESFS---QKYVLVLYQHECNIHVQDVAR--KI 251
C ++++ + + ++ GNVE +Y VLY E + Q + KI
Sbjct: 213 CVSYLEIEPNASLQCLD--------GNVEGGQVDGAQYCTVLYNDESHTFDQVIQTLTKI 264
Query: 252 SRALKKDISFGTFVLSQFDQDEHFTVIAESTNKAFMLRLKQELELQDIPTHLMNESNVFK 311
++ KD +++ D++ V ++ + L++ E ++ +PT L++ +
Sbjct: 265 AKCRAKD---AMEIVAAIDREGRAVVKCDTFEECNKLKVSIENQMI-LPTSLVSTAR--- 317
Query: 312 RYMISELVRWLHHFAVHNPSVLSGKLSLRLAYMDQYVSNLLAVKPFKINILG---NFIVP 368
+N S+ + L + +A + F + +LG F+V
Sbjct: 318 ----------------NNQSLRTSVLHI----------GAVACQQFALQLLGWFQEFLVR 351
Query: 369 HQKHNSFPWIKPWNFQSNSDETHDPNITNVMLIYDQKIRETDTPNTACRYLPLSGSRFQY 428
H F + +L YD K+ +T T L +SG +Y
Sbjct: 352 HYLFRK-------TFSELVQRKQETFCIRHILEYDVKLWKT--ARTCWHRLLISGMLMEY 402
Query: 429 FITECLTTFSQFTRMRLLEVFGSIFSVRDDSKKCLAAQYLDVYCNILYRTIVSDASGYKL 488
D+K LA ++ Y I+ +SD +
Sbjct: 403 -----------------------------DNKMILAQEFSRRYATIV-EDFISDDHDHAF 432
Query: 489 TLMSTLSQYIFPSPSTAN-MIINAGFIERCLTFSYSIMSSD---SEIVPNSPPIPLSSEF 544
+++S LS +F PS A+ +I + G ++ L Y + ++ + S I + F
Sbjct: 433 SIVS-LSVQLFTVPSIAHHLIAHEGIFDKLLHTFYHVAIEKFIRNKTLHFSKNIASLTFF 491
Query: 545 KLPDTVIKNKKAVICFKDIYQAMCTNTKPASVFANESLTNAMRECFFSFNKIL------- 597
K + ++ + + ++ K V +N+ L N E + ++L
Sbjct: 492 KRANYILYDLRYLLSLKP------------DVLSND-LRNGFLEGCRALMRVLNVMQGME 538
Query: 598 PLKRETSEHVQYE---NXXXXXXXXXXXXILIMVDGFLRNISLV--LDPIKRKQLVSTLL 652
+ R+T +H+ YE I ++D ++ L+ L + + LVS
Sbjct: 539 SMTRQTGQHMDYEPEWECAFNLHIKLATTISQVIDWASGDVKLLRKLYKMTMRALVSNSF 598
Query: 653 TTSIDKHLSSLDKFRPSIPGNTSNTFKTTVCNVQTRIFNFKVGSETQNFFNPISYYIKFI 712
+K + + + +N C V + + + + P+S + I
Sbjct: 599 IVGGEKVMQP-----KKVADHVAN------CLV------YDISVQPVSIHLPLSRFFAGI 641
Query: 713 LQWSQCGRYEPLPETLKDYFNFKEFFKSPTECLWIAEQALCTLVMISQIDVGFWVRNGSP 772
+ G ++ + L+ +P E I E LCT MI+Q+ G W RNG
Sbjct: 642 --YLHLGAHDLTYDGLQTETEALSIKLTPRE---IIEPVLCTQAMIAQVGAGLWRRNGYT 696
Query: 773 IQHQLKMYTKYSMREFTYFSDFFLVQFSMCYADPHDFMVNFLTRWGLKYWAEG-----IP 827
+ HQL Y R D +Q + ++F+++ L R+ W + +
Sbjct: 697 LLHQLYFYRNVRCRVEMLDRDIACLQIGASLMESNEFLIHVLNRFNTIPWLQENYWSLLS 756
Query: 828 IGDYPEESLTIAMTEQCFLTLIRLMTETRALCASTSVEGFESTMKSEIIHSLCFRKCSYS 887
+ ++ + A FL L+ ++ R + S+ E ++ EII LC + S+S
Sbjct: 757 GNEMNDDIIREASIFDEFLELLIVIIGERWM-PGVSMVTEEDRLRKEIIQLLCIKPYSHS 815
Query: 888 SLVEAIPEHVTKHP--AFDLYLNQYSDYHEPTGNFDTGTYSLKKQYRKQIDPFFVGFSSN 945
L A+P+ + + F+ +N + + +P G G Y LK+ K+ + +F ++
Sbjct: 816 ELSRALPDGNSGNSDNVFEEVINTVAVFKKPVGADSKGVYELKEHLLKEFNMYFYHYTKE 875
Query: 946 KRYEATLLVRERMKETYGVSFNDTFVQASSIQDQLRN--TQYQNLYQI-TSTDIFGVFVK 1002
+ +A L RER K + + +L T N+ Q +I + ++
Sbjct: 876 DKSKAEELQRERRK-----AKKQLVCCPPPMLPKLTPAFTPMANILQCPVFLNICSLIME 930
Query: 1003 NTLVHIMKMKLESLLGKVLHLIHLCVVNNLADFERIFWHEYHLDESENGFYHSIGSLLYN 1062
L + ES L KVLHL+ + L+ E + ++ E G + L
Sbjct: 931 RALNAYSRSFTESHLQKVLHLLGYAIQEELS--EHYPFLSFYERSQEYGILEKLEELARC 988
Query: 1063 FLSSDDFNVENGKIREIFRFLKDRAPHI-NVDDYLSEQTPNYDPRILFTDISESENEEYI 1121
++ I + +AP S+Q L E EE
Sbjct: 989 PRLEAHYDFVLWTIERFKQLQAKQAPSDGRAGPSCSQQGTGGK---LSLSAEEQAREERE 1045
Query: 1122 KKKMLAKSRREKLMQKLAKQQKEFMDNNNVSAEDISSQGTNLDNSAIG 1169
+ LA RR +M ++ K QK F+ +N D ++ T ++++ G
Sbjct: 1046 NRARLAAERRAHIMAQMQKAQKSFISSNAEMFADTENE-TRKESASTG 1092
>SPAC15A10.11 [O] KOG1140 N-end rule pathway recognition component UBR1
Length = 2052
Score = 107 bits (266), Expect = 2e-22
Identities = 105/480 (21%), Positives = 199/480 (40%), Gaps = 41/480 (8%)
Query: 696 SETQNFFNPISYYIKFILQWSQCGRYEPLPETLKDYFNFKEFFKSP----TECLWIAEQA 751
S NF P+ + F + Y PL L + F++ S L + +
Sbjct: 842 SSLTNFTQPL---VPFSVSRDPISFYHPLHWMLSNLFSYCRVDASSHWDKDTLLALLDHP 898
Query: 752 LCTLVMISQIDVGFWVRNGSPIQHQLKMYTKYSMREFTYFSDFFLVQFSMCYADPHDFMV 811
L V+++QID W+RNG I Y + + E +Y D +Q + + DP+ +
Sbjct: 899 LRVCVLLAQIDCNLWIRNGRSILLTDAFYRQLNNIEVSYDKDILAIQTILMFVDPNLVLN 958
Query: 812 NFLTRWGLKYWAEGIPIGDYP--EESLTIAMTEQCFLTLIRLMTETRALCASTSVEGFES 869
+ R+ W + ++P + AM + LI L+TE + +
Sbjct: 959 AVVQRFEFTDWLYNLTYNEHPNYDTERIPAMLCKMLELLIALITEREQILHVD----IQD 1014
Query: 870 TMKSEIIHSLCFRKCSYSSLVEAIPEHVTKHPAFDLYLNQYSDYHEPTGNFDTGTYSLKK 929
+++ + LCF +YS+L+ I ++ + +FD + + Y P G D G YSLK
Sbjct: 1015 IIRTRLAQQLCFGPLAYSALLSTISSNLVESLSFDKIREEVTSYKAPDGLHDFGVYSLKD 1074
Query: 930 QYRKQIDPFFVGFSSNKRYEATLLVRERMKETYGVSFNDTFVQASSIQDQLRNTQYQNLY 989
+Y +DP++ ++ N+R E+ ++++R+ + VS ++ L + +
Sbjct: 1075 EYYDLVDPYYFHYNKNEREESDTILKKRLAKKNNVSAESIIIEPKI--RFLEKDGHDIFF 1132
Query: 990 QITSTDIFGVFVKNTLVHIMKMKLES---------LLGKVLHL------IHLCVVNNLAD 1034
+ F + + + + + ++ ES +LG L L IH +N D
Sbjct: 1133 AAVNASTFSLIIFRAIEYAL-VQAESFGSSDIGNTILGDALQLCLISMKIHEFSKSN--D 1189
Query: 1035 F-ERIFWHEYHLDESE----NGFYHSIGSLLYNFLSSDDFNVENGKIREIFRFLKDRAPH 1089
F R Y D S G + + L + L S + + K+ + L+ P
Sbjct: 1190 FCSRSCAERYPTDSSIMREFGGSAYCLAELCFAILKSPKYKDVHVKVNAVLAGLQKNDP- 1248
Query: 1090 INVDDYLSEQTPNYDPRILFTDISESENEEYIKKKMLAKSRREKLMQKLAKQQKEFMDNN 1149
+ + E T +++ + +E E+ +KK LA +++K+MQ+ QQ F+ N
Sbjct: 1249 -SAYSNMLEAT-HFELSTTSSTSDSNEIEKTQEKKRLALEKQKKIMQQFRDQQASFLAQN 1306
Score = 71.6 bits (174), Expect = 1e-11
Identities = 82/346 (23%), Positives = 143/346 (40%), Gaps = 32/346 (9%)
Query: 1376 DIFMSLCSSMHMLSDDEHILHLLKTKLIEELSLRI-NEVAALSYQNDIPRQKKSFSIPYR 1434
D F+ + S M + ++IL+ +K + E+ I + + ++ + +P ++S +
Sbjct: 1710 DDFVKISSLMLIFGKQDNILYYVKLFYLSEICKTIISMIKVVADSSVVPDLTINYSQQSK 1769
Query: 1435 DVISQIIISRIHTTSVINQTEILKAEGIFRGNEMIFIDFIMVQFLIFLRKVCIALHSKY- 1493
+ + + N EIL E N + + + L FLR+V + L+ +
Sbjct: 1770 SQFYILCKNVLLWCGSSNNIEILDDES----NLLRLMSLVEKYSLPFLRRVALVLYCMFD 1825
Query: 1494 ISADKAVISG-KGYNELETMIDFCNLPPFIELLQELFCKNSSDPEG------SGKCSIVT 1546
IS + S + +ELE + +PP LQEL+ + SSD +G C +
Sbjct: 1826 ISLEFNEFSNNEDDSELERLSKLIKVPP----LQELYSQMSSDENNQILELIAGWCEHLA 1881
Query: 1547 RKP--------KIPVSSPFIDLPRVISYMSKQTDSEINLRFSAFKEDIAICMFCG-LSCI 1597
+ + P + LP + + + AICM CG + C
Sbjct: 1882 QNTWGDSTISLEYPGIYELVKLPHRLENLIDSMQESVCCMCHKTPILPAICMLCGSVICF 1941
Query: 1598 LQKVSLLHFSRI-GQCTNHYYNECKCKAPFGCFFILKSNIIYL--SYGSRGSFYQTPYVN 1654
+ + + R+ G+C H C G FFI K+ I L S + G+ TPY++
Sbjct: 1942 NARQNTVSSRRLTGECNKH---AATCTGSVGIFFITKACGILLLDSISNTGTIMPTPYLD 1998
Query: 1655 KHGETDEDYKLGTPVFFNKARYQHFIQDIMLSGKIPHLINRANDKT 1700
HGETD + G P F N+ RY +++ L + + R D T
Sbjct: 1999 IHGETDLQLRRGCPQFLNQKRYDFVVREQWLRQTVLQKMARHMDMT 2044
>Hs20555197 [O] KOG1140 N-end rule pathway recognition component UBR1
Length = 1242
Score = 91.3 bits (225), Expect = 1e-17
Identities = 119/558 (21%), Positives = 225/558 (39%), Gaps = 83/558 (14%)
Query: 747 IAEQALCTLVMISQIDVGFWVRNGSPIQHQLKMYTKYSMREFTYFSDFFLVQFSMCYADP 806
+ E L LV+ +Q+ G W RNG + +Q+ Y R + D ++Q + DP
Sbjct: 135 LIEHPLRCLVLCAQVHAGMWRRNGFSLVNQIYYYHNVKCRREMFDKDVVMLQTGVSMMDP 194
Query: 807 HDFMVNFLTRWGL----------KYWAEGIPIGDYPEESLTIAMTEQCFLTLIRLMTETR 856
+ F++ L+R+ L K ++ I D +++ T + E+ +I L+ E
Sbjct: 195 NHFLMIMLSRFELYQIFSTPDYGKRFSSEITHKDVVQQNNT--LIEEMLYLIIMLVGER- 251
Query: 857 ALCASTSVEGFEST--MKSEIIHSLCFRKCSYSSLVEAIPEHVTKHPAFDLYLNQYSDYH 914
S V +T +K EIIH L + ++S LV+++PE K + + + +
Sbjct: 252 ---FSPGVGQVNATDEIKREIIHQLSIKPMAHSELVKSLPEDENKETGMESVIEAVAHFK 308
Query: 915 EPTGNFDTGTYSLKKQYRKQIDPFFVGFSSNKRYEATLLVRERMKETYGVSFNDTFVQAS 974
+P G G Y LK + K+ + +F FS ++ +A E ++ + DT +
Sbjct: 309 KP-GLTGRGMYELKPECAKEFNLYFYHFSRAEQSKA----EEAQRKLKRQNREDTALPPP 363
Query: 975 SIQDQLRNTQYQNLYQITSTD----IFGVFVKNTLVHIMKMKLESLLGKVLHLIHLCVVN 1030
+ + +L I +D I G ++ + H ES+L +VLHLI + +
Sbjct: 364 VLPPFC--PLFASLVNILQSDVMLCIMGTILQWAVEHNGYAWSESMLQRVLHLIGMALQE 421
Query: 1031 NLADFERI---------FWHEYHLDESENGFYHSIGSLLYNFLSSDDFNVENGKIREIFR 1081
E + F + SI ++L ++ V IR I +
Sbjct: 422 EKQHLENVTEEHVVTFTFTQKISKPGEAPKNSPSILAMLETLQNAPYLEVHKDMIRWILK 481
Query: 1082 FLKDRAPHINVDDYLSEQTP-----NYDPRILFTDISESENEEYIKKKMLAKSRREKLMQ 1136
N + E +P + I+ + + E +K +A+ RREK+M
Sbjct: 482 -------TFNAVKKMRESSPTSPVAETEGTIMEESSRDKDKAERKRKAEIARLRREKIMA 534
Query: 1137 KLAKQQKEFMDNN----NVSAEDISSQGTNLDNSAIGICWT----------YPED----D 1178
++++ Q+ F+D N + E +S LD+S + T PE
Sbjct: 535 QMSEMQRHFIDENKELFQQTLELDASTSAVLDHSPVASDMTLTALGPAQTQVPEQRQFVT 594
Query: 1179 CVFCKMPKDYDVLSYFVFVERNVVSINLASDDKTKDVE----FQPVL-----------TT 1223
C+ C+ ++ V S + + V + S +++K ++ + P+ ++
Sbjct: 595 CILCQEEQEVKVESRAMVLAAFVQRSTVLSKNRSKFIQDPEKYDPLFMHPDLSCGTHTSS 654
Query: 1224 CGHCAHFGCLLSHMKSLR 1241
CGH H C + S++
Sbjct: 655 CGHIMHAHCWQRYFDSVQ 672
Score = 52.8 bits (125), Expect = 5e-06
Identities = 56/244 (22%), Positives = 99/244 (39%), Gaps = 26/244 (10%)
Query: 1486 CIALHSKYISADKAV--ISGKGYNELETMIDFCNLP-----------PFIELLQELFCKN 1532
C AL Y++ + I G + E + + +LP + L E +C+N
Sbjct: 1005 CSALFFHYLNGVPSPPDIQVPGTSHFEHLCSYLSLPNNLICLFQENSEIMNSLIESWCRN 1064
Query: 1533 SSDPEGSGKCSIVTRKPKIPVSSPFIDLPRVISYMSKQTDSEINLRFSAFKEDI-AICMF 1591
S R P+ S+ I+LP S + Q + + K +C+
Sbjct: 1065 SEVKRYLEGERDAIRYPR--ESNKLINLPEDYSSLINQASNFSCPKSGGDKSRAPTLCLV 1122
Query: 1592 CGLSCILQKVSL---LHFSRIGQCTNHYYNECKCKAPFGCFF-ILKSNIIYLSYGSRGSF 1647
CG Q L +G CT H Y+ C + G F + + +++L+ ++G F
Sbjct: 1123 CGSLLCSQSYCCQTELEGEDVGACTAHTYS---CGSGVGIFLRVRECQVLFLAGKTKGCF 1179
Query: 1648 YQTPYVNKHGETDEDYKLGTPVFFNKARYQHFIQDIMLSGKIPHLINRANDKTVDVGG-- 1705
Y PY++ +GETD+ + G P+ K R++ IQ + + I A + + G
Sbjct: 1180 YSPPYLDDYGETDQGLRRGNPLHLCKERFKK-IQKLWHQHSVTEEIGHAQEANQTLVGID 1238
Query: 1706 WESM 1709
W+ +
Sbjct: 1239 WQHL 1242
>At5g02300 [O] KOG1140 N-end rule pathway recognition component UBR1
Length = 1225
Score = 57.8 bits (138), Expect = 1e-07
Identities = 55/219 (25%), Positives = 90/219 (40%), Gaps = 18/219 (8%)
Query: 747 IAEQALCTLVMISQIDVGFWVRNGSPIQHQLKMYTKYSMREFTYFSDFFLVQFSMCYADP 806
+ E L V +Q+ G W +NG E D FL+Q A
Sbjct: 753 VMEHVLQIRVFCAQVIAGMWKKNGD------SALVSCEWSEQGLELDLFLLQCCAALAPA 806
Query: 807 HDFMVNFLTRWGLKYWAEGIPIGDYPEESLTIAMTEQCFLTLIRLMTETRALCASTSVEG 866
++ L+R+GL + P D E + I + + LI+++ E R ST+
Sbjct: 807 DSYVDKLLSRFGLSSYLSLNP--DITNEYVPIVLLLEMLGLLIQILQERRFCGLSTA--- 861
Query: 867 FESTMKSEIIHSLCFRKCSYSSLVEAIPEHVTKHPAFDLYLNQYSDYHEPTGNFDTGTYS 926
+++ EII L ++S LV+++P ++K L+ S Y P+G + G YS
Sbjct: 862 --ESLRREIIFKLATGDFTHSQLVKSLPRDLSKSDELQEVLDDVSVYCNPSG-MNQGKYS 918
Query: 927 LKKQYRKQIDPFFVGFSSNKRYEATLLVRERMKETYGVS 965
L+ K++D + + S A ER GVS
Sbjct: 919 LQSSCWKELDLYHPRWQSRDLQSA----EERFSRYCGVS 953
>CE08535 [O] KOG1140 N-end rule pathway recognition component UBR1
Length = 1927
Score = 56.6 bits (135), Expect = 3e-07
Identities = 106/523 (20%), Positives = 198/523 (37%), Gaps = 75/523 (14%)
Query: 660 LSSLDKFRPSIPGNTSNTFKTTVC--NVQTRIFNFKVGSETQNFFNPI----------SY 707
L +++ P + +T++ TV RI +F V + + P+ S
Sbjct: 590 LELMNRMPPVYTKSEEDTYELTVTINGESCRISHFDVLKSSTSVHQPVVRIIAGLFSASN 649
Query: 708 YIKFILQWSQCGRYEPLPETLKDYFNFKEFFKSPTECLWIAEQALCTLVMISQIDVGFWV 767
Y F+L S E +K+ N K+ + E +L LV+ +Q + W
Sbjct: 650 YTGFLLNRSNNSHTSLNQERIKELINCKDETN-------LYELSLRVLVLCAQSNATLWR 702
Query: 768 RNGSPIQHQLKMYTKYSMREFTYFSDFFLVQFSMCYADPHDFMVNFLTRWGLKYWAEGIP 827
RNG + +Q+ Y R + D ++Q F+ + L R+ L WA
Sbjct: 703 RNGFSLINQIHNYFSPLCRNEMFDRDVLMMQVGAALTPSTKFIFHLLHRFRLFKWATSEF 762
Query: 828 IGDYPEESLTIAMTEQCFLTLIRLMTETRALCASTSVEGFE---------STMKSEIIHS 878
D E +E TL+ + E E + MK E+IH
Sbjct: 763 EQDKANEKPAKPESEDLSKTLVMIAEEFIQCLILILCERYTYGVGKTRPMDQMKREVIHI 822
Query: 879 LCFRKCSYSSLVEAIPEHV-TKHPAFDLYLNQYSDYHEPTGNFDTGTYSLKKQYRKQIDP 937
LC ++S + + + + +K + +N +D+ +P G + K+ P
Sbjct: 823 LCTGSHTFSHIQQKMSHDINSKRLSLHEAVNLVADFRKPLAT-TAGQFHCKESSLPTYSP 881
Query: 938 FFVGFSSNKR---YEATLLVRERMKETYGVSFNDTFVQASSIQDQLRNTQYQNLYQITST 994
FF+ +S + + ++ VR +M+++ A I + T ++ + +I +T
Sbjct: 882 FFMHYSKSDQSAAEQSQARVRAKMEKSVRAC-------APPILPDFQ-TFFERIPEILTT 933
Query: 995 DIFGVFVKNTLVHIMKMKL-----------ESLLGKVLHLIHLCVVNNLADFERIFWHEY 1043
N L+H++++ + + L K L+LI + + N + F
Sbjct: 934 --------NVLIHVVRLIIDRTARRSRFSSDRLFHKTLYLIGIAL--NEEEKNPSFGFTQ 983
Query: 1044 HLDESENGFYHSIGSLLYNFLSSDDFNVENGKIREIFRFLKDRAPHINVDDYLSEQTPNY 1103
+ES G + L+ SS + + + + +K RA V + + P
Sbjct: 984 RAEES-IGLLSLLEGLVGKPESSICPILLEVTVEKYRKLIKARA---GVPE--AAPAPEN 1037
Query: 1104 DPRILFTDISESENEEYIKKKMLAKSRREKLMQKLAKQQKEFM 1146
P ++SE E K+ A R+K M K++ Q +FM
Sbjct: 1038 KP-------AQSEEEIKAKRAARAAEMRQKAMAKMSNMQSKFM 1073
>Hs18597977 [O] KOG1140 N-end rule pathway recognition component UBR1
Length = 717
Score = 55.1 bits (131), Expect = 1e-06
Identities = 45/170 (26%), Positives = 80/170 (46%), Gaps = 8/170 (4%)
Query: 728 LKDYFNFKEFFKSPTECLWIAEQALCTLVMISQIDVGFWVRNGSPIQHQLKMYTKYSMRE 787
L ++ +F++F + + E L LV+++Q+ W RNG + Q+ Y RE
Sbjct: 555 LHEFVSFEDF-----QVEVLVEYPLRCLVLVAQVVAEMWRRNGLSLISQVFYYQDVKCRE 609
Query: 788 FTYFSDFFLVQFSMCYADPHDFMVNFLTRWGL-KYWAEGIPIGDYPEESLTIAMTEQCFL 846
Y D ++Q DP+ F++ L R+ L + + + I D + E+
Sbjct: 610 EMYDKDIIMLQIGASLMDPNKFLLLVLQRYELAEAFNKTISTKDQDLIKQYNTLIEEMLQ 669
Query: 847 TLIRLMTETRALCASTSVEGFESTMKSEIIHSLCFRKCSYSSLVEAIPEH 896
LI ++ E R + +V E TM+ EIIH LC +S++ + +PE+
Sbjct: 670 VLIYIVGE-RYVPGVGNVTKEEVTMR-EIIHLLCIEPMPHSAIAKNLPEN 717
>Hs22044520 [O] KOG1139 Predicted ubiquitin-protein ligase of the N-recognin
family
Length = 258
Score = 52.0 bits (123), Expect = 8e-06
Identities = 31/112 (27%), Positives = 55/112 (48%), Gaps = 5/112 (4%)
Query: 1584 EDIAICMFCGLSCILQKVSLLHFSRIGQCTNHYYNECKCKAPFGCFFILKSNIIYLSYGS 1643
+D A+C+ CG L+ + S +C H N C A G F ++ +++I + G
Sbjct: 144 KDPAVCLVCGTFVCLKGLCCKQQSYC-ECVLHSQN---CGAGTGIFLLINASVIIIIRGH 199
Query: 1644 RGSFYQTPYVNKHGETDEDYKLGTPVFFNKARYQHFIQDIMLSGKIPHLINR 1695
R + + Y++ HGE D D + G P++ K RY+ ++ +S H+ R
Sbjct: 200 RFCLWGSVYLDAHGEEDRDLRRGKPLYICKERYK-VLEQQWISHTFDHINKR 250
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.323 0.138 0.417
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 103,802,397
Number of Sequences: 60738
Number of extensions: 4635979
Number of successful extensions: 11132
Number of sequences better than 1.0e-05: 9
Number of HSP's better than 0.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 11087
Number of HSP's gapped (non-prelim): 32
length of query: 1709
length of database: 30,389,216
effective HSP length: 120
effective length of query: 1589
effective length of database: 23,100,656
effective search space: 36706942384
effective search space used: 36706942384
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)