ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI4107 good RT KOG0748 General function prediction only Predicted membrane proteins, contain hemolysin III domain
r_klactVI4107 good RT KOG0748 Signal transduction mechanisms Predicted membrane proteins, contain hemolysin III domain
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI4107 1433494 1435359 622
(622 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YLR023c [RT] KOG0748 Predicted membrane proteins contain hemolys... 444 e-124
SPAC30D11.11 [RT] KOG0748 Predicted membrane proteins contain he... 154 3e-37
HsM7705761 [RT] KOG0748 Predicted membrane proteins contain hemo... 90 9e-18
Hs21361519 [RT] KOG0748 Predicted membrane proteins contain hemo... 90 9e-18
SPBC12C2.09c [RT] KOG0748 Predicted membrane proteins contain he... 90 1e-17
At5g20270 [RT] KOG0748 Predicted membrane proteins contain hemol... 88 3e-17
At4g30850 [RT] KOG0748 Predicted membrane proteins contain hemol... 86 2e-16
YOL002c [RT] KOG0748 Predicted membrane proteins contain hemolys... 84 6e-16
CE24200 [RT] KOG0748 Predicted membrane proteins contain hemolys... 81 5e-15
YDR492w [RT] KOG0748 Predicted membrane proteins contain hemolys... 77 1e-13
CE27848 [RT] KOG0748 Predicted membrane proteins contain hemolys... 75 4e-13
7299917 [RT] KOG0748 Predicted membrane proteins contain hemolys... 74 5e-13
Hs13375715 [RT] KOG0748 Predicted membrane proteins contain hemo... 71 6e-12
At2g24150 [RT] KOG0748 Predicted membrane proteins contain hemol... 71 6e-12
Hs18556998 [RT] KOG0748 Predicted membrane proteins contain hemo... 65 2e-10
>YLR023c [RT] KOG0748 Predicted membrane proteins contain hemolysin III
domain
Length = 543
Score = 444 bits (1142), Expect = e-124
Identities = 208/366 (56%), Positives = 269/366 (72%), Gaps = 17/366 (4%)
Query: 269 DLFIEDPHS----IKKTIQFYNWDNACDLGRQRHLHFYELPFPWRENRYIIHGYRFYDSH 324
++ IE+P + IK I YN A LG +HLH+Y+LPFPWRENRYIIHGYRFY++H
Sbjct: 182 EILIEEPLNPTTDIKSFINSYNHGKAYSLGETQHLHYYQLPFPWRENRYIIHGYRFYNTH 241
Query: 325 VKSVLSVVNWYGWHNETLNIWSHLFGAVYLAYLLFIQLPTTKVFMSQDVPLFGKLIIQVF 384
KS+LS+ NWYGWHNET NIWSHL GA+Y+ YL P ++V+ + VP + I+ +F
Sbjct: 242 SKSLLSIFNWYGWHNETSNIWSHLLGAIYIIYLAIYDFPQSEVWRNSQVPPQARWIVFMF 301
Query: 385 LIAGVKCLLSSSVWHTLNGTCCLPLRCKFACIDYTGITVLITASILSTEFVSVYNLATQS 444
L A +KC+LSS WHT NGT L LR KFAC+DY+GIT+LITASIL+TEFV++Y S
Sbjct: 302 LAAALKCMLSSVFWHTFNGTSFLKLRSKFACVDYSGITILITASILTTEFVTMY-----S 356
Query: 445 LSTSMTVYMSLSLCLGIFGSFMNWSPRFDRPESRPFRIAFYVLLAGLGMISFLHLTISRG 504
+M YMS+SL LG+FG FMNWSPRFDRPE+RP RI F++LLA +G++SFLHL
Sbjct: 357 CYWAMYTYMSISLALGVFGVFMNWSPRFDRPEARPLRIRFFILLATMGVLSFLHLIFLTD 416
Query: 505 IDHSSQFFKPVWNRSLIWYLIGVVFYGSFIPERWRTDVELDYTIPTDAELCSNLDILTKH 564
+ +++ F PV +S++WYL+GVVFYGSFIPER+R+DV++D TIPT+ EL ++L+I+TK
Sbjct: 417 LHYAATLFSPVTYKSVVWYLVGVVFYGSFIPERFRSDVQVDKTIPTNYELSTDLEIITKQ 476
Query: 565 KHVHFRAVPSKSSR--------TGFFSLWWVDYFLSSHTLWHFFVLLGVIGHYNALLDMF 616
+ +HFR VP+ S+ F SLWWVDYF SHT WHFFV+LGVIGHY A+LDMF
Sbjct: 477 REIHFREVPTAHSKCSSCPSHAKSFKSLWWVDYFGCSHTFWHFFVVLGVIGHYRAILDMF 536
Query: 617 ETKWQL 622
+W L
Sbjct: 537 AKRWIL 542
>SPAC30D11.11 [RT] KOG0748 Predicted membrane proteins contain hemolysin III
domain
Length = 442
Score = 154 bits (390), Expect = 3e-37
Identities = 114/388 (29%), Positives = 180/388 (46%), Gaps = 66/388 (17%)
Query: 243 ETIDDKCVDIDT--QQVIQTLDFLDEHLDLFIEDPHSIKKTIQFYNWD------NACDLG 294
ET +D DT + + L FL+ HL + K ++ D +A LG
Sbjct: 105 ETYNDVLSACDTFPAKAQKALTFLEHHLRDLEDYAEKSKNNVETLMTDIKDVVEHAAKLG 164
Query: 295 RQRHLHFYELPFPWRENRYIIHGYRFYDSHVKSVLSVVNWYGWHNETLNIWSHLFGAVYL 354
QR + ELP W N YII GYRFY S K S+++ WHNET NIW+HL +
Sbjct: 165 AQRLITLEELPVQWHNNPYIIRGYRFYTSKRKCFRSILS---WHNETFNIWTHLSAFIVF 221
Query: 355 AYLLFIQLPTTKVFMSQDVPLFGKLIIQVFLIAGVKCLLSSSVWHTLNGTCCLP-LRCKF 413
+L P++ ++S +V +++ FL++ +KCL S +WHT + +RC
Sbjct: 222 FAVLAYFYPSSSSWVSSNVS--NRIVRIFFLLSAMKCLGCSVIWHTFSSLSNYKHMRCA- 278
Query: 414 ACIDYTGITVLITASILSTEFVSVYNLATQSLSTSMTVYMSLSLCLGIFGSFMNWSPRFD 473
AC+DY GI+ LI ASI+S E+ A ++++ + LG+ G + W F+
Sbjct: 279 ACMDYVGISALIAASIISVEY-----HAFVCQGPLRFIFIAFTGTLGLIGIYTPWKKWFN 333
Query: 474 RPESRPFRIAFYVLLAGLGMISFLHLTISRGIDHSSQFFKPVWNRSLIWYLIGVVFYGSF 533
+ R +I F+V LA G+I + + +G + ++ PV+ +S+ Y+IGV+FYG
Sbjct: 334 EYKYRSVKIFFFVGLACSGLIPMITMFYIKGTRRTVKYLDPVF-KSIFSYIIGVLFYGLH 392
Query: 534 IPERWRTDVELDYTIPTDAELCSNLDILTKHKHVHFRAVPSKSSRTGFFSLWWVDYFLSS 593
IPER+ +P K D +S
Sbjct: 393 IPERF---------------------------------LPGK-----------FDIIGNS 408
Query: 594 HTLWHFFVLLGVIGHYNALLDMFETKWQ 621
H +WH +++GV HY + FET ++
Sbjct: 409 HQIWHIAIIVGVAFHYTG-VKRFETDYE 435
>HsM7705761 [RT] KOG0748 Predicted membrane proteins contain hemolysin III
domain
Length = 370
Score = 90.1 bits (222), Expect = 9e-18
Identities = 78/279 (27%), Positives = 132/279 (46%), Gaps = 28/279 (10%)
Query: 268 LDLFIEDPHSIKKTIQFYN--WDNACDLGRQRHLHFYELPFPWRENRYIIHGYR----FY 321
L L ++ H+++K +F W+ GR R + + LP ++N Y++HG+R +
Sbjct: 67 LTLPLQAHHAMEKMEEFVYKVWE-----GRWRVIPYDVLPDWLKDNDYLLHGHRPPMPSF 121
Query: 322 DSHVKSVLSVVNWYGWHNETLNIWSHLFGAVYLAYL-LFIQLPTTKVFMSQDVPLFGKLI 380
+ KS+ + H ET NIW+HL G V +L + L FM+ PL K++
Sbjct: 122 RACFKSIFRI------HTETGNIWTHLLGFVLFLFLGILTMLRPNMYFMA---PLQEKVV 172
Query: 381 IQVFLIAGVKCLLSSSVWHTLNGTCCLPLRCKFACIDYTGITVLITASILSTEFVSVYNL 440
+F + V CL S ++HT+ R F+ +DY+GI +LI S + + S Y
Sbjct: 173 FGMFFLGAVLCLSFSWLFHTVYCHSEKVSRT-FSKLDYSGIALLIMGSFVPWLYYSFYCS 231
Query: 441 ATQSLSTSMTVYMSLSLCLGIFGSFMNWSPRFDRPESRPFRIAFYVLLAGLGMISFLHLT 500
L +Y+S+ LGI + RF P+ R R ++ L G++ +H T
Sbjct: 232 PQPRL-----IYLSIVCVLGISAIIVAQWDRFATPKHRQTRAGVFLGLGLSGVVPTMHFT 286
Query: 501 ISRGIDHSSQFFKPVWNRSL-IWYLIGVVFYGSFIPERW 538
I+ G ++ + W + + Y+ G Y + IPER+
Sbjct: 287 IAEGFVKATTVGQMGWFFLMAVMYITGAGLYAARIPERF 325
>Hs21361519 [RT] KOG0748 Predicted membrane proteins contain hemolysin III
domain
Length = 375
Score = 90.1 bits (222), Expect = 9e-18
Identities = 78/279 (27%), Positives = 132/279 (46%), Gaps = 28/279 (10%)
Query: 268 LDLFIEDPHSIKKTIQFYN--WDNACDLGRQRHLHFYELPFPWRENRYIIHGYR----FY 321
L L ++ H+++K +F W+ GR R + + LP ++N Y++HG+R +
Sbjct: 67 LTLPLQAHHAMEKMEEFVYKVWE-----GRWRVIPYDVLPDWLKDNDYLLHGHRPPMPSF 121
Query: 322 DSHVKSVLSVVNWYGWHNETLNIWSHLFGAVYLAYL-LFIQLPTTKVFMSQDVPLFGKLI 380
+ KS+ + H ET NIW+HL G V +L + L FM+ PL K++
Sbjct: 122 RACFKSIFRI------HTETGNIWTHLLGFVLFLFLGILTMLRPNMYFMA---PLQEKVV 172
Query: 381 IQVFLIAGVKCLLSSSVWHTLNGTCCLPLRCKFACIDYTGITVLITASILSTEFVSVYNL 440
+F + V CL S ++HT+ R F+ +DY+GI +LI S + + S Y
Sbjct: 173 FGMFFLGAVLCLSFSWLFHTVYCHSEKVSRT-FSKLDYSGIALLIMGSFVPWLYYSFYCS 231
Query: 441 ATQSLSTSMTVYMSLSLCLGIFGSFMNWSPRFDRPESRPFRIAFYVLLAGLGMISFLHLT 500
L +Y+S+ LGI + RF P+ R R ++ L G++ +H T
Sbjct: 232 PQPRL-----IYLSIVCVLGISAIIVAQWDRFATPKHRQTRAGVFLGLGLSGVVPTMHFT 286
Query: 501 ISRGIDHSSQFFKPVWNRSL-IWYLIGVVFYGSFIPERW 538
I+ G ++ + W + + Y+ G Y + IPER+
Sbjct: 287 IAEGFVKATTVGQMGWFFLMAVMYITGAGLYAARIPERF 325
>SPBC12C2.09c [RT] KOG0748 Predicted membrane proteins contain hemolysin III
domain
Length = 324
Score = 89.7 bits (221), Expect = 1e-17
Identities = 72/247 (29%), Positives = 117/247 (47%), Gaps = 39/247 (15%)
Query: 307 PWRE-NRYIIHGYR-----FYDSHVKSVLSVVNWYGWHNETLNIWSHLFGAVYLAYLLFI 360
PW++ N+YII GYR FY VKS+ V HNE++NIW+HLFGA+ + +F
Sbjct: 56 PWQQDNQYIISGYRPPSFSFYLC-VKSIFHV------HNESVNIWTHLFGAIVFLFFIF- 107
Query: 361 QLPTTKVFMSQDVPLFGKL-IIQVFLIAGVKCLLSSSVWHTLNGTCCLPLRCKFA-CIDY 418
+++ + +D + +I VFL + L S+ +HT++ KF +DY
Sbjct: 108 ---KSELILKRDTTTAEDVYVITVFLFSAFTMLGCSTFYHTISNHS--DDVSKFGNKLDY 162
Query: 419 TGITVLITASILSTEFVSVYNLATQSLSTSMTVYMSLSLCLGIFGSFMNWSPRFDRPESR 478
GI V+I S F+ + A + T+Y+ + +G+ + RF +PE R
Sbjct: 163 LGIVVMIVGS-----FIPCLHYAFACHANFRTLYIGTIIGIGVIVASTCLLDRFRQPEWR 217
Query: 479 PFRIAFYVLLAGLGMISFLHLTISRGIDHSSQFFKPVWNRSLIW-------YLIGVVFYG 531
P+R +VL+ G+ +H F + + L+W Y++G V Y
Sbjct: 218 PYRALIFVLMGLFGIFPVIHAL------KIFSFSEILVRMGLVWLLLQGLFYIVGAVIYA 271
Query: 532 SFIPERW 538
IPE+W
Sbjct: 272 LRIPEKW 278
>At5g20270 [RT] KOG0748 Predicted membrane proteins contain hemolysin III
domain
Length = 332
Score = 88.2 bits (217), Expect = 3e-17
Identities = 80/324 (24%), Positives = 122/324 (36%), Gaps = 60/324 (18%)
Query: 295 RQRHLHFYELPFPWRENRYIIHGYRFYDSHVKSVLSVVNWYGWHNETLNIWSHLFGAVYL 354
R+ + + ELP ++N YI++ YR S + SV + +HNE+LN+W+HL G ++
Sbjct: 53 RRELMSYCELPEYMKDNEYILNYYRADWSIRDAFFSV---FSFHNESLNVWTHLIGFIFF 109
Query: 355 AYLLFIQLPTTKVFMSQDVPLFGKLI---IQVFLIAGVKCLLSSSVWHTLNGTCC--LPL 409
L + F D G + VFL + CLL+SS+ H CC L
Sbjct: 110 VALTVANIIHHDGFFPVDAKSPGNVTRWPFFVFLGGSMFCLLASSICHLF---CCHSKEL 166
Query: 410 RCKFACIDYTGITVLITASILSTEFVSVYNLATQSLSTSMTVYMSLSLCLGIFGSFMNWS 469
IDY GIT +I S F Q +Y++ +GIF ++
Sbjct: 167 NVFLLRIDYAGITAMIITSFFPPIF-----YIFQCTPRWYFIYLAGITSMGIFTIITLFT 221
Query: 470 PRFDRPESRPFRIAFYVLLAGLGMISFLHLTISRGIDHSSQFFKPVWNRSLIWYLIGVVF 529
P P+ R FR + + G++ H + + ++YL+G F
Sbjct: 222 PSLSAPKYRAFRALLFASMGLFGIVPAAHALVVNWGNPQRNVTLVYELLMAVFYLVGTGF 281
Query: 530 YGSFIPERWRTDVELDYTIPTDAELCSNLDILTKHKHVHFRAVPSKSSRTGFFSLWWVDY 589
Y +PER + W D
Sbjct: 282 YVGRVPERLKPG--------------------------------------------WFDR 297
Query: 590 FLSSHTLWHFFVLLGVIGHYNALL 613
SH ++H FVLLG + HY A L
Sbjct: 298 VGHSHQIFHVFVLLGALSHYAAAL 321
>At4g30850 [RT] KOG0748 Predicted membrane proteins contain hemolysin III
domain
Length = 405
Score = 85.9 bits (211), Expect = 2e-16
Identities = 74/272 (27%), Positives = 119/272 (43%), Gaps = 37/272 (13%)
Query: 296 QRHLHFYELPFPWRENRYIIHGYRFYDSHVKSVLSVVNWYGWHNETLNIWSHLFG-AVYL 354
+R + F ELP ++N +I + YR S ++ LS + WHNETLNIW+HL G A++
Sbjct: 29 KRLMKFEELPRYLKDNEFIHNHYRCEWSIKETFLSA---FSWHNETLNIWTHLCGFAIFT 85
Query: 355 AYLLFIQLPTTKVFMSQDVPLFGKLIIQVFLIAGVKCLLSSSVWHTLNG----------- 403
++ + TT++ ++ V L I Q+ + G +L + +G
Sbjct: 86 WMMVVSSMETTELGLAGFVSLLSGKIKQISIFLGDLWVLMTEQQFAGHGRQWQCQKMFTS 145
Query: 404 ----TCCLPLRCKFAC-----------IDYTGITVLITASILSTEFVSVYNLATQSLSTS 448
C + FAC +DY GI+++I S F +Y A +
Sbjct: 146 PAIKLCITSMSHLFACHSRRFNLFFWRLDYAGISLMIVCSF----FAPIY-YAFSCHTYW 200
Query: 449 MTVYMSLSLCLGIFGSFMNWSPRFDRPESRPFRIAFYVLLAGLGMISFLHLTISRGIDHS 508
Y+S LG+ F SP P R FR A ++ + G+I H+ DH
Sbjct: 201 RLFYLSSISILGLLAIFTLLSPSLSAPRFRSFRAALFLTMGFSGVIPATHVLYLHK-DHP 259
Query: 509 SQFFKPVWNRSL-IWYLIGVVFYGSFIPERWR 539
+ V+ ++ + Y G FY + IPERW+
Sbjct: 260 NVLIALVYELAMAVLYATGAAFYVTRIPERWK 291
>YOL002c [RT] KOG0748 Predicted membrane proteins contain hemolysin III
domain
Length = 327
Score = 84.0 bits (206), Expect = 6e-16
Identities = 79/305 (25%), Positives = 136/305 (43%), Gaps = 49/305 (16%)
Query: 283 QFYNWDNACDLGRQRHLHFYELPFPWRENRYIIHGY-RFYDSHVKSVLSVVNWYGWHNET 341
+ Y+WD E+P R+N +I+HGY + S +++ S+ + HNE+
Sbjct: 48 RLYSWD--------------EIPEWQRDNDFILHGYVKETSSFIETFKSL---FYLHNES 90
Query: 342 LNIWSHLFGAVYLAYLLFIQLPTTKVFMSQDVPLFGKLIIQVFLIAGVKCLLSSSVWHTL 401
+NI+SHL A+ +L + T KVF + ++I +F CL+ SS +H L
Sbjct: 91 VNIYSHLIPALGFFTVLLLDKSTIKVFAT--TTWLDHMVIDLFYSGAFACLILSSSFHCL 148
Query: 402 NGTCCLPLRCKFACIDYTGITVLITASILSTEFVSVYNLATQSLSTSMTVYMSLSLCLGI 461
+ L + +DY GI +LI S++S + + + ++ +++ GI
Sbjct: 149 K-SHSLRIATLGNKLDYLGICILIVTSMVSILYYGYF-----EKFSLFCLFALITVSFGI 202
Query: 462 FGSFMNWSPRFDRPESRPFRIAFYVLLAGLGMISFLHLTISRGIDHSSQFFKPVWNR-SL 520
S ++ +F + E RP+R +V GL I + I G+ S F +W + L
Sbjct: 203 ACSIVSLKDKFRKREWRPYRAGLFVCF-GLSSI----IPIFSGLYCYS--FSEIWTQIQL 255
Query: 521 IW-------YLIGVVFYGSFIPER--------WRTDVELDYTIPTDAELCSNLDILTKHK 565
W Y+IG V YG PE+ W +L + + A LC +L ++
Sbjct: 256 FWVLLGGVLYIIGAVLYGMRFPEKICPGKFDIWGHSHQLFHFLVVIAALCHLRGLLNSYE 315
Query: 566 HVHFR 570
VH +
Sbjct: 316 LVHIK 320
>CE24200 [RT] KOG0748 Predicted membrane proteins contain hemolysin III
domain
Length = 640
Score = 80.9 bits (198), Expect = 5e-15
Identities = 79/331 (23%), Positives = 137/331 (40%), Gaps = 75/331 (22%)
Query: 295 RQRHLHFYELPFPWRENRYIIHGYR----FYDSHVKSVLSVVNWYGWHNETLNIWSHLFG 350
R + +F LP ++N Y+ G+R + S KS+ ++ H ET NIW+H++G
Sbjct: 267 RWKATNFETLPEWLQDNEYLRTGHRPPLPSFSSCFKSIFAL------HTETGNIWTHMYG 320
Query: 351 AV--YLAYLLFIQLPTTKVFMSQDVPLFGKLIIQVFLIAGVKCLLSSSVWHTLNGTC-CL 407
V + + F+ P ++ + KLI F + V CL S ++HT+ C +
Sbjct: 321 CVAFFGIGIWFLTRPHDQMQWVE------KLIYSAFFLGAVICLGMSFLFHTV--ACHSI 372
Query: 408 PLRCKFACIDYTGITVLITASILSTEFVSVYNLATQSLSTSMTVYMSLSLCLGIFGSFMN 467
+ F+ +DYTGI++LI S + + + Y M +Y + + LGI ++
Sbjct: 373 EMAKLFSKLDYTGISLLIVGSFVPWIYFAFY-----CRPQPMIIYNGMIIILGIAAMVVS 427
Query: 468 WSPRFDRPESRPFRIAFYVLLAGLGMISFLHLTISRGIDH---SSQFFKPVWNRSLIWYL 524
+F P+ RP R A ++ + ++ HL + G+ + SQ + ++ Y+
Sbjct: 428 LWDKFAEPKFRPVRAAVFIAMGLSAVVPAFHLLVVDGVHYMVEESQVHLMIMMGAM--YI 485
Query: 525 IGVVFYGSFIPERWRTDVELDYTIPTDAELCSNLDILTKHKHVHFRAVPSKSSRTGFFSL 584
G Y + +PE R P K
Sbjct: 486 GGATLYATRVPE---------------------------------RCFPGK--------- 503
Query: 585 WWVDYFLSSHTLWHFFVLLGVIGHYNALLDM 615
D + SH L+H FV+L HY+A+ M
Sbjct: 504 --CDIWFQSHQLFHTFVVLAAFVHYHAISQM 532
>YDR492w [RT] KOG0748 Predicted membrane proteins contain hemolysin III
domain
Length = 316
Score = 76.6 bits (187), Expect = 1e-13
Identities = 82/343 (23%), Positives = 146/343 (41%), Gaps = 90/343 (26%)
Query: 295 RQRHLH-FYELPFPWRENRYIIHGYRFYDSHVKSVLS----VVNWYGWHNETLNIWSHLF 349
+Q+ LH F ELP ++N I+ GY V+ LS + + + W+NET+NI++HL
Sbjct: 36 KQKLLHNFDELPEWQKDNDKILTGY------VRETLSWKKCLYSLFYWNNETVNIYTHLV 89
Query: 350 GAVYLAYLLFIQLPTTKVFMSQDVPLFGK------LIIQVFLIAGVKCLLSSSVWHTLNG 403
A+ Y +F + T F+ +P+F +I +FL+ CL+ SS +H
Sbjct: 90 PAI--VYFVF-AITLTNYFL---IPVFPSTSWSDYTVINIFLMGAFSCLMCSSCFH---- 139
Query: 404 TCCLPLRCK-----FACIDYTGITVLITASILSTEFVSVYNLATQSLSTSMTVYMSLSLC 458
C+ + ++ +DY GI LI+ S++ + ++ + +++ ++L
Sbjct: 140 --CMKQHSEKQSNFWSKLDYLGIISLISCSMIPIIYFGYFDHISY-----FSLFTIVTLV 192
Query: 459 LGIFGSFMNWSPRFDRPESRPFRIAFYVLLAGLGMI----SFLHLTISRGIDHSSQFFKP 514
L F + +F+ RPFR F++L G++ F I +G+ + +
Sbjct: 193 LATFCTVCVLHDKFNTSTFRPFRAMFFILFGFSGLLPLTTGFFKFGI-QGVLNRIKVSFV 251
Query: 515 VWNRSLIWYLIGVVFYGSFIPERWRTDVELDYTIPTDAELCSNLDILTKHKHVHFRAVPS 574
W ++Y+ G V YG IPE P
Sbjct: 252 FW--EALFYISGAVIYGFRIPE---------------------------------TLAPG 276
Query: 575 KSSRTGFFSLWWVDYFLSSHTLWHFFVLLGVIGHYNALLDMFE 617
K D+F SSH ++H V+LG + H A++D ++
Sbjct: 277 K-----------FDFFGSSHQIFHIMVVLGSVCHLKAIIDSYK 308
>CE27848 [RT] KOG0748 Predicted membrane proteins contain hemolysin III
domain
Length = 434
Score = 74.7 bits (182), Expect = 4e-13
Identities = 69/254 (27%), Positives = 113/254 (44%), Gaps = 31/254 (12%)
Query: 295 RQRHLHFYELPFPWRENRYIIHGYR----FYDSHVKSVLSVVNWYGWHNETLNIWSHLFG 350
R + L + LP ++N ++ HG+R + KS+ S+ H ET NIW+HL G
Sbjct: 157 RWKVLKYEHLPEWLQDNEFLRHGHRPPLPSFSECFKSIWSL------HTETGNIWTHLIG 210
Query: 351 AVYLAYLL--FIQLPTTKVFMSQDVPLFGKLIIQVFLIAGVKCLLSSSVWHTLNGTCCLP 408
V +L F+ P + + K++ F V CL S +HTL+ C
Sbjct: 211 CVAFFFLACWFLTRPDNHIQFQE------KVVFSFFFAGAVLCLGLSFAFHTLS--CHSV 262
Query: 409 LRCKFAC-IDYTGITVLITASILSTEFVSVYNLATQSLSTSMTVYMSLSLCLGIFGSFMN 467
K C +DY GI++LI S + + Y ++ Y+++ LGI ++
Sbjct: 263 NVVKIFCKLDYMGISLLIIGSFIPWIYYGFYCRREPKIT-----YIAMVSVLGIGAIVVS 317
Query: 468 WSPRFDRPESRPFRIAFYVLLAGLGMISFLHLTISRGIDHSSQFFKPVWNRSLIW---YL 524
+F RP R A +V + G+I +H I+ G+ S F ++ L+ YL
Sbjct: 318 LWDKFSESRFRPIRAAVFVGMGCSGVIPTIHYIITDGV--HSLFADNSFHWLLLMAFLYL 375
Query: 525 IGVVFYGSFIPERW 538
+G Y + PER+
Sbjct: 376 LGAGLYATRTPERF 389
>7299917 [RT] KOG0748 Predicted membrane proteins contain hemolysin III
domain
Length = 351
Score = 74.3 bits (181), Expect = 5e-13
Identities = 86/333 (25%), Positives = 146/333 (43%), Gaps = 63/333 (18%)
Query: 231 KLKLDRSEMCEL----ETIDDKCVDIDTQQVIQTLDFL-----DEHLDLFIEDPHSIKKT 281
+L LD S C L + DD C+ +D Q V ++D +E ++ P+ K
Sbjct: 13 ELSLDSSS-CYLRKSGQDCDDSCL-LDGQLVADSVDAAHQFPSNEEPNILGHGPNYDDKL 70
Query: 282 IQFY---NWDNACDLGRQRHLHFYELPFPWRENRYIIHGYRFYDSHVKSVLSVVNWYGWH 338
+F N+D+A HL F N YI GYR + K L + W W
Sbjct: 71 SKFKWLCNFDDA-----PSHLKF---------NPYIRRGYRTFLPSTKMCLQSIFW--WT 114
Query: 339 NETLNIWSHLFGAVYLAYLLFIQLPTTKVFMSQDVPLFGKLIIQVFLIAGVKCLLSSSVW 398
NET+NIWSHL G + L L F+ L ++++ L+ C+L S+++
Sbjct: 115 NETINIWSHLAGCILFIGLTIFDLQ----FLRLHASLSDQVLVVCLLVCFCLCMLMSAIY 170
Query: 399 HTLNGTCCLPLRCK-------FACIDYTGITVLITASILSTEFVSVYNLATQSLSTSMTV 451
H + CK F +D+ GI++ + A +S + + + + T+
Sbjct: 171 HIFS--------CKSEEHYELFLSVDFLGISLSLVAIYISGMYYAFW-----CHTFLRTL 217
Query: 452 YMSLSLCLGIFG-SFMNWSPRFDRPESRPFRIAFYVLLAGLGMISFLHLTISRGIDHSSQ 510
Y +++ LG+F + PR + S ++A +L + G+I H ++ G ++
Sbjct: 218 YSTIA--LGMFALAIAVQIPRLN--VSMNGKVAVLLLWSAYGIIPLGHWAVAMG-GLENE 272
Query: 511 FFKPVWNRSLIWY---LIGVVFYGSFIPERWRT 540
+ + R ++ Y L+ VFY + IPERW T
Sbjct: 273 LVRLMVPRIVLMYLLCLVAFVFYAAKIPERWFT 305
>Hs13375715 [RT] KOG0748 Predicted membrane proteins contain hemolysin III
domain
Length = 258
Score = 70.9 bits (172), Expect = 6e-12
Identities = 70/291 (24%), Positives = 116/291 (39%), Gaps = 63/291 (21%)
Query: 338 HNETLNIWSHLFGAV-YLAYLLFIQLPTTKVFMSQDVPLFGKLIIQVFLIAGVKCLLSSS 396
H ET NIW+HL G V +L +F F++ PL K++ +F + + CL S
Sbjct: 15 HTETGNIWTHLLGCVSFLCLGIFYMFRPNISFVA---PLQEKVVFGLFFLGAILCLSFSW 71
Query: 397 VWHTL----NGTCCLPLRCKFACIDYTGITVLITASILSTEFVSVYNLATQSLSTSMTVY 452
++HT+ G L F+ +DY+GI +LI S + + S Y +Y
Sbjct: 72 LFHTVYCHSEGVSRL-----FSKLDYSGIALLIMGSFVPWLYYSFYCNPQPCF-----IY 121
Query: 453 MSLSLCLGIFGSFMNWSPRFDRPESRPFRIAFYVLLAGLGMISFLHLTISRGIDHSSQFF 512
+ + LGI ++ F P+ R R ++ L G+I LH IS G ++
Sbjct: 122 LIVICVLGIAAIIVSQWDMFATPQYRGVRAGVFLGLGLSGIIPTLHYVISEGFLKAATIG 181
Query: 513 KPVWNRSLI-WYLIGVVFYGSFIPERWRTDVELDYTIPTDAELCSNLDILTKHKHVHFRA 571
+ W + Y+ G Y + IPER+
Sbjct: 182 QIGWLMLMASLYITGAALYAARIPERF--------------------------------- 208
Query: 572 VPSKSSRTGFFSLWWVDYFLSSHTLWHFFVLLGVIGHYNALLDMFETKWQL 622
P K D + SH L+H FV+ G H++ + ++ E ++ +
Sbjct: 209 FPGK-----------CDIWFHSHQLFHIFVVAGAFVHFHGVSNLQEFRFMI 248
>At2g24150 [RT] KOG0748 Predicted membrane proteins contain hemolysin III
domain
Length = 301
Score = 70.9 bits (172), Expect = 6e-12
Identities = 73/262 (27%), Positives = 113/262 (42%), Gaps = 42/262 (16%)
Query: 296 QRHLHFYELPFPWRENRYIIHGYRFYDSHVKSVLSVVNWYGWHNETLNIWS--------- 346
+R + F +LP ++N +I + YR S + LS + WHNETLNIW+
Sbjct: 20 RRLMKFEDLPEYLKDNEFIHNHYRCQWSLKDTFLSA---FSWHNETLNIWTSFEIDFVEI 76
Query: 347 -----HLFGAVYLAYLLFIQLPTTKVFMSQDVPLFGKLIIQVFL-IAGVKCLLSSSVWHT 400
HL G + +F+ + + ++ L G VF +AG + SSV H
Sbjct: 77 LIIVRHLIG-----FGIFLWMTVVSCLETTEISLAG-----VFNGMAGYE--PPSSVSHL 124
Query: 401 LNGTCCLPLRCK--FACIDYTGITVLITASILSTEFVSVYNLATQSLSTSMTVYMSLSLC 458
L C R F +DY GI+++I AS F +Y A +Y+S
Sbjct: 125 L---ACHSKRFNVFFWRLDYAGISLMIVASF----FAPIY-YAFSCHPNFRLLYLSSISI 176
Query: 459 LGIFGSFMNWSPRFDRPESRPFRIAFYVLLAGLGMISFLHLTISRGIDHSSQFFKPVWN- 517
LG+ SP P RPFR ++ + +I H+ + DH + F +
Sbjct: 177 LGLLAIITLLSPALSTPRFRPFRANLFLAMGSSAVIPATHV-LCLYWDHPNVFIALGYEI 235
Query: 518 RSLIWYLIGVVFYGSFIPERWR 539
+ + Y +G FY S +PERW+
Sbjct: 236 ATALSYFVGATFYVSRVPERWK 257
>Hs18556998 [RT] KOG0748 Predicted membrane proteins contain hemolysin III
domain
Length = 311
Score = 65.5 bits (158), Expect = 2e-10
Identities = 68/246 (27%), Positives = 114/246 (45%), Gaps = 19/246 (7%)
Query: 299 LHFYE-LPFPWRENRYIIHGYRFYDSHVKSVLSVVNWYGWHNETLNIWSHLFGAVYLAYL 357
L+ YE +P ++N YI GYR Y + S L + + + NET+NIWSHL G +L +
Sbjct: 30 LYTYEQIPGSLKDNPYITDGYRAY---LPSRLCIKSLFILSNETVNIWSHLLG-FFLFFT 85
Query: 358 LFIQLPTTKVFMSQDVPLFGKLIIQVFLIAGVKCLLSSSVWHTLNGTCCLPLRCKFACID 417
L I T V S +I + L C+L S +H + ++ +D
Sbjct: 86 LGI-YDMTSVLPSASASREDFVICSICLFCFQVCMLCSVGYHLFSCHRSEKTCRRWMALD 144
Query: 418 YTGITVLITASILSTEFVSVYNLATQSLSTSMTVYMSLSLCLGIFGSFMNWSPRFDRPES 477
Y GI++ I +S F + Y + + + L++ L +F F P + +
Sbjct: 145 YAGISIGILGCYVSGVFYAFY---CNNYWRQVYLITVLAMILAVF--FAQIHPNYLTQQW 199
Query: 478 RPFRIAFYVLLAGLGMISFLH-LTISRGIDHS-SQFFKPVWNRSLIWYLIGV---VFYGS 532
+ R + ++G G+I LH + ++ GI Q F P R ++ Y+I + +FY S
Sbjct: 200 QRLRSIIFCSVSGYGVIPTLHWVWLNGGIGAPIVQDFAP---RVIVMYMIALLAFLFYIS 256
Query: 533 FIPERW 538
+PER+
Sbjct: 257 KVPERY 262
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.325 0.138 0.433
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,587,193
Number of Sequences: 60738
Number of extensions: 1456022
Number of successful extensions: 5239
Number of sequences better than 1.0e-05: 15
Number of HSP's better than 0.0 without gapping: 1
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 5174
Number of HSP's gapped (non-prelim): 30
length of query: 622
length of database: 30,389,216
effective HSP length: 112
effective length of query: 510
effective length of database: 23,586,560
effective search space: 12029145600
effective search space used: 12029145600
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)