ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI4120 good I KOG2624 Lipid transport and metabolism Triglyceride lipase-cholesterol esterase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI4120 1437595 1439130 512
(512 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YLR020c [I] KOG2624 Triglyceride lipase-cholesterol esterase 530 e-150
YLL012w [I] KOG2624 Triglyceride lipase-cholesterol esterase 427 e-119
SPCC1672.09 [I] KOG2624 Triglyceride lipase-cholesterol esterase 107 4e-23
Hs4758676 [I] KOG2624 Triglyceride lipase-cholesterol esterase 95 2e-19
CE28762 [I] KOG2624 Triglyceride lipase-cholesterol esterase 88 3e-17
SPBC16A3.12c [I] KOG2624 Triglyceride lipase-cholesterol esterase 88 3e-17
CE18732 [I] KOG2624 Triglyceride lipase-cholesterol esterase 84 4e-16
YKL140w [I] KOG2624 Triglyceride lipase-cholesterol esterase 84 7e-16
Hs4557721 [I] KOG2624 Triglyceride lipase-cholesterol esterase 78 4e-14
CE29647 [I] KOG2624 Triglyceride lipase-cholesterol esterase 74 7e-13
CE18444 [I] KOG2624 Triglyceride lipase-cholesterol esterase 74 7e-13
CE05874 [I] KOG2624 Triglyceride lipase-cholesterol esterase 73 1e-12
Hs17489494_2 [I] KOG2624 Triglyceride lipase-cholesterol esterase 72 2e-12
Hs22055273 [I] KOG2624 Triglyceride lipase-cholesterol esterase 71 3e-12
7297743 [I] KOG2624 Triglyceride lipase-cholesterol esterase 70 8e-12
7297734 [I] KOG2624 Triglyceride lipase-cholesterol esterase 69 2e-11
7297722 [I] KOG2624 Triglyceride lipase-cholesterol esterase 68 3e-11
SPBC14C8.15 [I] KOG2624 Triglyceride lipase-cholesterol esterase 68 4e-11
7297727 [I] KOG2624 Triglyceride lipase-cholesterol esterase 68 4e-11
CE11708 [I] KOG2624 Triglyceride lipase-cholesterol esterase 65 2e-10
Hs17489492 [I] KOG2624 Triglyceride lipase-cholesterol esterase 65 3e-10
CE24406 [I] KOG2624 Triglyceride lipase-cholesterol esterase 65 3e-10
CE26551 [I] KOG2624 Triglyceride lipase-cholesterol esterase 64 5e-10
7303096 [I] KOG2624 Triglyceride lipase-cholesterol esterase 63 1e-09
7301402 [I] KOG2624 Triglyceride lipase-cholesterol esterase 62 2e-09
7302156 [I] KOG2624 Triglyceride lipase-cholesterol esterase 62 3e-09
7296316 [I] KOG2624 Triglyceride lipase-cholesterol esterase 61 5e-09
7299754 [I] KOG2624 Triglyceride lipase-cholesterol esterase 60 1e-08
At2g15230 [I] KOG2624 Triglyceride lipase-cholesterol esterase 58 4e-08
7297730 [I] KOG2624 Triglyceride lipase-cholesterol esterase 57 7e-08
7299660 [I] KOG2624 Triglyceride lipase-cholesterol esterase 56 1e-07
7295808 [I] KOG2624 Triglyceride lipase-cholesterol esterase 56 1e-07
CE09169 [I] KOG2624 Triglyceride lipase-cholesterol esterase 53 1e-06
7297731 [I] KOG2624 Triglyceride lipase-cholesterol esterase 52 2e-06
>YLR020c [I] KOG2624 Triglyceride lipase-cholesterol esterase
Length = 538
Score = 530 bits (1366), Expect = e-150
Identities = 282/534 (52%), Positives = 356/534 (65%), Gaps = 46/534 (8%)
Query: 9 VVSRLITVCFLTVLMICAIWHNFFTSHLLKRKQRIILDPRDTRAANV-ITPQTTGHSHMV 67
+VS +I F+T L I ++W N+ T H + DPRDTR++ I P
Sbjct: 12 LVSAIILTSFMTGLFILSLWKNYVTVHFQHKN-----DPRDTRSSRTKIQPNDKKKKRPA 66
Query: 68 RR-RTESFSSLVPLXXXXXXXXXNNIEYDRTISRR----------------------TEL 104
R R S SS PL NNIEYDRT++ + T +
Sbjct: 67 RHSRPLSISSTTPLDLQRDQE--NNIEYDRTVTSKLSMTSNASLSENGDGNANIKMETNV 124
Query: 105 KDSDF---NPFSDILSAEDLKLVPNLQYYYSQYNIIIDEYEVTTKDGFILELWHLRNE-N 160
+ + NPF +I AED KLVP+L+YYY +Y I I+E+EV T DGFI++LWH ++ N
Sbjct: 125 NQAPYAAENPFQNIALAEDTKLVPDLKYYYKEYGIDIEEFEVETDDGFIIDLWHFKSRLN 184
Query: 161 EGKTNTKY-PVLMLHXXXXXXXXXXXXXXXXXAYYMHDSGYDVWLGNNRCGFNSKWDREK 219
+G K P+L+LH AY++++SG+DVWLGNNRCG N+KW+ +K
Sbjct: 185 DGVEEVKREPILLLHGLLQSCGAFASSGRKSLAYFLYESGFDVWLGNNRCGLNAKWNMKK 244
Query: 220 L--TPNGEWDWDLDSMTRYDLEALIESVLQKKQNKFEKLTLVAHSQGTTQAFMGLVNGEE 277
L + +WDWD+ M +YDL+ALI VL + KL+LVAHSQGTTQ FMGLVNGE+
Sbjct: 245 LGNDHSKKWDWDMHQMVQYDLKALINYVLDS--TGYAKLSLVAHSQGTTQGFMGLVNGEK 302
Query: 278 IYKNTEFRLSDKLDNLVALAPAVYPGPLLDEKYFVKFMAKHIDNRWVFGNKSFVPMMMEM 337
+Y + +F+L DKL+N VALAPAVYPGPLLDEK FV+ MAK ID+ W FG +SF+P+MM M
Sbjct: 303 LYAS-DFKLVDKLENFVALAPAVYPGPLLDEKAFVRLMAKGIDSPWYFGRRSFIPLMMTM 361
Query: 338 RNLLAGHKIFSFLSYVMFNYLFNWNDILWDRPLRDRHFLFSPVHISVKLMQWWLSLNPLK 397
R L+ G KIFSFLSY+MFNYLF+WND+LWDR LRDR+FLFSPVHISVKLMQWWLS P K
Sbjct: 362 RKLMVGTKIFSFLSYIMFNYLFDWNDVLWDRVLRDRNFLFSPVHISVKLMQWWLSPLPNK 421
Query: 398 SSFKTFAEDMFPDIKTWFPI-QNETVS---MDEH-LHRNQHKPLPENWPKILLFTPRQDR 452
SFK AE +FPD KTWFPI +N+ S +D + LH N + E +P I++F P+QDR
Sbjct: 422 LSFKKGAEKIFPDKKTWFPIAKNDDDSGNNLDNNKLHLNPKRQNSEEFPHIIMFIPKQDR 481
Query: 453 LVDGERLINHFINHEPHSVYKIWYIDEYSHLDVLWASDVIERIGNPMLAHLRIP 506
LVDGERLINHFINHE ++VYKIWYIDEYSHLDVLWA DVI+RIG PM+ +LR P
Sbjct: 482 LVDGERLINHFINHEANAVYKIWYIDEYSHLDVLWAHDVIDRIGKPMIENLRFP 535
>YLL012w [I] KOG2624 Triglyceride lipase-cholesterol esterase
Length = 573
Score = 427 bits (1097), Expect = e-119
Identities = 210/402 (52%), Positives = 266/402 (65%), Gaps = 29/402 (7%)
Query: 110 NPFSDILSAEDLKLVPNLQYYYSQYNIIIDEYEVTTKDGFILELWHL---RNENEGKTNT 166
NP +++ +EDL LV +L YY++QYNI I+E+ + T+DGF+++LWHL +
Sbjct: 161 NPLQNLILSEDLTLVADLNYYFNQYNIQIEEFRLETEDGFVIDLWHLIPKYRTTDSDKKK 220
Query: 167 KYPVLMLHXXXXXXXXXXXXXXXXXAYYMHDSGYDVWLGNNRCGFNSKWDREKL-TPNGE 225
+ P+LMLH AY+++ SGYD+WLGNNRCGF +W+ K+ T
Sbjct: 221 RPPILMLHGLLQSSGSFASNGRKSLAYFLYQSGYDIWLGNNRCGFRPEWNEAKVPTLASR 280
Query: 226 WDWDLDSMTRYDLEALIESVLQKKQNKFEKLTLVAHSQGTTQAFMGLVNGEEIYK----N 281
WDWDL M +YDL LI++VL K Q FEKLTL++HSQGTTQ FMGLVN ++ + +
Sbjct: 281 WDWDLREMVKYDLTLLIDTVLAKTQ--FEKLTLISHSQGTTQGFMGLVNEDKFFPPGSGS 338
Query: 282 TEFRLSDKLDNLVALAPAVYPGPLLDEKYFVKFMAKHIDNRWVFGNKSFVPMMMEMRNLL 341
E + K+ N +ALAPAVYPGPLL+EK FVK M K I+N W FG SF +MM +RNL
Sbjct: 339 KESFFTSKIANYIALAPAVYPGPLLNEKLFVKLMTKEIENPWFFGETSFFEIMMIVRNLC 398
Query: 342 AGHKIFSFLSYVMFNYLFNWNDILWDRPLRDRHFLFSPVHISVKLMQWWLSLNPLKSSFK 401
G +FSF+ Y +FNYLF+WND LWD LRDRHFLFSPVH+SVKLMQWWLS +P K SFK
Sbjct: 399 VGESLFSFVCYTIFNYLFDWNDTLWDTALRDRHFLFSPVHVSVKLMQWWLSPDPNKVSFK 458
Query: 402 TFAEDMFPDIKTWFPIQNETVSMDEHLHRNQHKPLPENWPKILLFTPRQDRLVDGERLIN 461
+ MFPD WF ++ P I LF P+QDRLVDGERLIN
Sbjct: 459 FGSHKMFPDNVKWFSDASKA-------------------PNIYLFVPKQDRLVDGERLIN 499
Query: 462 HFINHEPHSVYKIWYIDEYSHLDVLWASDVIERIGNPMLAHL 503
HF+N E + YKIWYIDEY+H+DVLWA DVIERIG P+L +L
Sbjct: 500 HFVNVESNVNYKIWYIDEYAHIDVLWAHDVIERIGKPILQNL 541
>SPCC1672.09 [I] KOG2624 Triglyceride lipase-cholesterol esterase
Length = 467
Score = 107 bits (267), Expect = 4e-23
Identities = 111/428 (25%), Positives = 184/428 (42%), Gaps = 59/428 (13%)
Query: 93 EYDRTISRRTELKDSDFNPFSDILSAEDLKLVPNLQYYYSQYNIIIDEYEVTTKDGFILE 152
E + +R+ + I A D++ + + YY ++++ V T+D +IL
Sbjct: 53 EIKKRSKKRSRSRSVSLQRAKAIHDAADIREMCKISGYY------VEDHLVRTEDDYILC 106
Query: 153 LWHLRNENEGKTNT----KYPVLMLHXXXXXXXXXXXXXXXXXAYYMHD---SGYDVWLG 205
+ + ++ G+ + K PV+ H + D GYDVWLG
Sbjct: 107 IHRISKDSPGRIGSPHPKKLPVVYCHHGLLMNSEVWVCNVDPRNCLVFDLVNKGYDVWLG 166
Query: 206 NNRCGFNSKWDREKL----TPNGEWDWDLDSMTRYDLEALIESVLQKKQNKFEKLTLVAH 261
NNR +K+ R+ L T WD+ +D +YD+ I+ +L K + KLT +
Sbjct: 167 NNR---GNKYSRQHLRFDSTDKEFWDFSIDDFAQYDIPDTIDYIL--KTSGQTKLTYIGF 221
Query: 262 SQGTTQAFMGLVNGEEIYKNTEFRLSDKLDNLVALAPAVYPGPLLDEKYFVKFMAKHIDN 321
SQGT QAF L + L+DK+++L+ALAPA+ P L + A+
Sbjct: 222 SQGTAQAFASL--------SIHPLLNDKINSLIALAPAISPKGLHNRVVDAFVKARPSIL 273
Query: 322 RWVFGNKSFVPMMMEMRNLLAGHKIFSFLSYVMFNYLFNW---NDILWDRPLRDRHFLFS 378
++FG KS +P ++ LA + L+Y + + LFNW N + R + H L+S
Sbjct: 274 FFLFGRKSILPSAGFWQSFLAPKFFDAVLAYCL-SQLFNWSCQNISSYQRLVSFAH-LYS 331
Query: 379 PVHISVKLMQWWLSLNPLKSSFKTFAEDMFPDIKTWFPIQNETVSMDEHLHRNQHKPLPE 438
+ SVK + W + + F+ + N+ + D L + P
Sbjct: 332 --YTSVKCLVHWFQIMR-SAEFRMY--------------DNDQLGHDYFLKYYKAAKFPT 374
Query: 439 NWPK--ILLFTPRQDRLVDGERLINHFINHEPHSVYKIWYIDEYSHLDVLWASDVIERIG 496
N + I L D LVD + ++N H +D Y HLD++WA V + +
Sbjct: 375 NNIRTPIYLIWGGSDSLVDIQAMLNALPAEVEHVK-----VDSYEHLDMIWADTVKDYVI 429
Query: 497 NPMLAHLR 504
P+L LR
Sbjct: 430 PPVLRRLR 437
>Hs4758676 [I] KOG2624 Triglyceride lipase-cholesterol esterase
Length = 398
Score = 95.1 bits (235), Expect = 2e-19
Identities = 101/389 (25%), Positives = 163/389 (40%), Gaps = 70/389 (17%)
Query: 139 DEYEVTTKDGFILELWHLR--NENEGKTNTKYPVLMLHXXXXXXXXXXXXX-XXXXAYYM 195
+EYEV T+DG+ILE+ + +N G T + V + H A+ +
Sbjct: 47 EEYEVVTEDGYILEVNRIPYGKKNSGNTGQRPVVFLQHGLLASATNWISNLPNNSLAFIL 106
Query: 196 HDSGYDVWLGNNRCGFNSKWDREKLTPNGE----WDWDLDSMTRYDLEALIESVLQKKQN 251
D+GYDVWLGN+R + W R L + + W + D M +YDL A I+ +++K
Sbjct: 107 ADAGYDVWLGNSR---GNTWARRNLYYSPDSVEFWAFSFDEMAKYDLPATIDFIVKKTGQ 163
Query: 252 KFEKLTLVAHSQGTTQAFMGLVNGEEIYKNTEFRLSDKLDNLVALAPAV---YPGPLLDE 308
K +L V HSQGTT F+ +T L+ ++ ALAP Y L+++
Sbjct: 164 K--QLHYVGHSQGTTIGFIAF--------STNPSLAKRIKTFYALAPVATVKYTKSLINK 213
Query: 309 KYFVKFMAKHIDNRWVFGNKSFVP------------MMMEMRNLLAGHKIFSFLSYVMFN 356
FV +++FG+K F P EM NLL + +F + N
Sbjct: 214 LRFVPQSL----FKFIFGDKIFYPHNFFDQFLATEVCSREMLNLLCSNALFIICGFDSKN 269
Query: 357 YLFNWNDILWDRPLRDRHFLFSPVHISVKLMQWWLSLNPLKSSFKTFAEDMFPDIKTWFP 416
FN + + D + +P SV+ M W + F P
Sbjct: 270 --FNTSRL-------DVYLSHNPAGTSVQNMFHWT---------QAVKSGKFQAYDWGSP 311
Query: 417 IQNETVSMDEHLHRNQHKPLPENWP----KILLFTPRQDRLVDGERLINHFINHEPHSVY 472
+QN +H +Q +P N I ++ +D L D + + + P+ +Y
Sbjct: 312 VQN-------RMHYDQSQPPYYNVTAMNVPIAVWNGGKDLLADPQD-VGLLLPKLPNLIY 363
Query: 473 KIWYIDEYSHLDVLWASDVIERIGNPMLA 501
I Y+HLD +WA D + + N +++
Sbjct: 364 H-KEIPFYNHLDFIWAMDAPQEVYNDIVS 391
>CE28762 [I] KOG2624 Triglyceride lipase-cholesterol esterase
Length = 404
Score = 88.2 bits (217), Expect = 3e-17
Identities = 74/227 (32%), Positives = 103/227 (44%), Gaps = 32/227 (14%)
Query: 141 YEVTTKDGFILELWHLRNENEGKTNTKYP------VLMLHXXXXXXXXXXXXX-XXXXAY 193
Y VTT DG+ILEL + + GKTN +P V M H A+
Sbjct: 44 YSVTTDDGYILELHRIPH---GKTNVTWPNGKQPVVFMQHGLLCASTDWTMNLPEQSAAF 100
Query: 194 YMHDSGYDVWLGNNRCG-FNSKWDREKLTPNGEWDWDLDSMTRYDLEALIESVLQKKQNK 252
D+G+DVWLGN R ++ K K + + W+W D M YDL A+I+ VL+
Sbjct: 101 IFADAGFDVWLGNMRGNTYSMKHKNLKASHSDFWEWSWDEMATYDLPAMIDKVLEVTGQ- 159
Query: 253 FEKLTLVAHSQGTTQAFMGLVNGEEIYKNTEFRLSDKLDNLVALAPAVYPGPLLDEKYFV 312
E L + HSQGT F L + I+ + K+ ALAP G + D K F+
Sbjct: 160 -ESLYYMGHSQGTLTMFSHLSKDDGIF-------AKKIKKFFALAPV---GSVKDIKGFL 208
Query: 313 KFMAKHID---NRW--VFGNKSFVP----MMMEMRNLLAGHKIFSFL 350
F A + + W VFG F+P M + +++ G KI S L
Sbjct: 209 SFFAHYFSLEFDGWFDVFGAGEFLPNNWAMKLAAKDICGGLKIESDL 255
>SPBC16A3.12c [I] KOG2624 Triglyceride lipase-cholesterol esterase
Length = 443
Score = 87.8 bits (216), Expect = 3e-17
Identities = 102/373 (27%), Positives = 165/373 (43%), Gaps = 56/373 (15%)
Query: 138 IDEYEVTTKDGFILELWHLRNENEGKTNTKYPVLMLHXXXXXXXX---XXXXXXXXXAYY 194
++E+ V T+D FIL L + + + + K V+ H +
Sbjct: 86 VEEHLVRTQDNFILCLHRITHPKQSQH--KREVVYCHHGLMTNSELWVAVNESERSLPFV 143
Query: 195 MHDSGYDVWLGNNRCGFNSKWDREKLT--PNGE--WDWDLDSMTRYDLEALIESVLQKKQ 250
+ +SGYDVWLGNNR +K+ R+ +T P E W++ LD M +D+ ++ +L ++
Sbjct: 144 LIESGYDVWLGNNR---GNKYSRKHITYKPKDEEFWNFSLDDMAMFDIPDTVDYIL--RE 198
Query: 251 NKFEKLTLVAHSQGTTQAFMGL-VNGEEIYKNTEFRLSDKLDNLVALAPAVYPGPLLDEK 309
EKL + SQGT QA L +N + L+DK++ + LAPA P
Sbjct: 199 TGREKLNYIGFSQGTAQAMAALSINPD---------LNDKVNIFIGLAPAYAPKGF--SN 247
Query: 310 YFVKFMAKHIDN--RWVFGNKSFVPMMMEMRNLLAGHKIFSFLSYVMFNYLFNW--NDIL 365
YFV ++ K +FG + +P + +N + IF + V LFNW ++I
Sbjct: 248 YFVDYIVKVNPKIMYHLFGRRCLLPSVTFWQN-ICYPPIFVKIVDVSLKILFNWDLSNIS 306
Query: 366 WDRPLRDRHFLFSPVHISVKLMQWWLSLNPLKSSFKTFAEDMFPDIKTWFPIQNETVSMD 425
++ L L+S SVK + WL + +F+ + +DM +
Sbjct: 307 LNQKLCGYAHLYS--FSSVKSVVHWLQIIK-NCTFQLYDDDM--------------ALLA 349
Query: 426 EHLHRNQHKPL-PENWPK--ILLFTPRQDRLVDGERLINHFINHEPHSVYKIWYIDEYSH 482
+ R+ PL P N K +L+ +D L++ E + PH+ K I Y H
Sbjct: 350 GYGSRHYQVPLFPTNNIKCPMLILWGGKDTLINMEVMRTAL---PPHA--KEVSIAHYEH 404
Query: 483 LDVLWASDVIERI 495
LD LW DV E +
Sbjct: 405 LDFLWGQDVKEEV 417
>CE18732 [I] KOG2624 Triglyceride lipase-cholesterol esterase
Length = 405
Score = 84.3 bits (207), Expect = 4e-16
Identities = 72/223 (32%), Positives = 102/223 (45%), Gaps = 32/223 (14%)
Query: 141 YEVTTKDGFILELWHLRNENEGKTNTKYP------VLMLHXXXXXXXXXXXXXXXXXAYY 194
Y+VTT+DG+ILEL + GKTN +P V M H A +
Sbjct: 45 YDVTTEDGYILELHRIPY---GKTNVTWPNGKKPVVFMQHGLECSSSNWVVNLPTESAAF 101
Query: 195 MH-DSGYDVWLGNNRCG-FNSKWDREKLTPNGEWDWDLDSMTRYDLEALIESVLQKKQNK 252
+ D+GYDVWLGN R ++ K K + + WDW D M +YDL A+IE L+
Sbjct: 102 LFADAGYDVWLGNFRGNTYSMKHKNLKPSHSAFWDWSWDEMQQYDLPAMIEKALEVTGQ- 160
Query: 253 FEKLTLVAHSQGTTQAFMGLVNGEEIYKNTEFRLSDKLDNLVALAPAVYPGPLLDEKYFV 312
+ L + HSQGT F L + + N K+ ALAP G + K +
Sbjct: 161 -DSLYYIGHSQGTLTMFSRLSEDKVGWGN-------KIKKFFALAPV---GSVKHIKGAL 209
Query: 313 KFMAKHID---NRW--VFGNKSFVP----MMMEMRNLLAGHKI 346
KF A + + W VFG+ F+P M + ++ AG K+
Sbjct: 210 KFFADYFSLEFDGWFDVFGSGEFLPNNWIMKLVSESVCAGLKV 252
>YKL140w [I] KOG2624 Triglyceride lipase-cholesterol esterase
Length = 548
Score = 83.6 bits (205), Expect = 7e-16
Identities = 92/383 (24%), Positives = 159/383 (41%), Gaps = 47/383 (12%)
Query: 119 EDLKLVPNLQYYYSQYNIIIDEYEVTTKDGFILELWHLRNENEGKTNTKYPVLMLHXXXX 178
E L+ P + + ++I ++++ V T+D +IL L + ++ + N K V+ LH
Sbjct: 58 EKLRSAPTIHEMCAIFDISVEDHLVRTEDNYILTLHRIPPISKNRFNNK--VVYLHHGLL 115
Query: 179 XXXXX---XXXXXXXXAYYMHDSGYDVWLGNNRCGFNSKWDREKLT----PNGEWDWDLD 231
+ +HD GYDVW+GNNR +K+ L N WD+ +D
Sbjct: 116 MCSDVWCCNIERHKNLPFVLHDLGYDVWMGNNR---GNKYSTAHLNKPPKSNKFWDFSID 172
Query: 232 SMTRYDLEALIESVLQKKQNKFEKLTLVAHSQGTTQAFMGLVNGEEIYKNTEFRLSDKLD 291
+D+ IE +L K +K+ + SQG+ Q F E +L+ K+
Sbjct: 173 EFAFFDIPNSIEFILD--ITKVDKVICIGFSQGSAQMFAAFSLSE--------KLNRKVS 222
Query: 292 NLVALAPAVYPGPLLDEKYFVKFMAKHIDN--RWVFGNKSFVPMMMEMRNLLAGHKIFSF 349
+ +A+APA+ P L V +AK FG K +P + + L +F+
Sbjct: 223 HFIAIAPAMTPKGL--HNRIVDTLAKSSPGFMYLFFGRKIVLPSAVIWQRTL-HPTLFNL 279
Query: 350 LSYVMFNYLFNWN--DILWDRPLRDRHFLFSPVHISVKLMQWWLSLNPLKSSFKTFAEDM 407
+ LFNW +IL + + L+S + ++ W+ L K +++M
Sbjct: 280 CIDIANKILFNWKSFNILPRQKIASYAKLYSTTSVK-SIVHWFQILRSQKFQMFEESDNM 338
Query: 408 FPDIKTWFPIQNETVSMDEHLHRNQHKPLPENWPKILLFTPRQDRLVDGERLINHFINHE 467
+ + I N + + ILL D LVD + + N
Sbjct: 339 LNSLTRPYQIANFPTRTNIKI-------------PILLIYGGIDSLVDIDVMKK---NLP 382
Query: 468 PHSVYKIWYIDEYSHLDVLWASD 490
+SV+ + +D Y HLD++W D
Sbjct: 383 FNSVFDV-KVDNYEHLDLIWGKD 404
>Hs4557721 [I] KOG2624 Triglyceride lipase-cholesterol esterase
Length = 399
Score = 77.8 bits (190), Expect = 4e-14
Identities = 101/411 (24%), Positives = 162/411 (38%), Gaps = 62/411 (15%)
Query: 116 LSAEDLKLVPNLQYYYSQYNIIIDEYEVTTKDGFILELWHLRN--ENEGKTNTKYPVLML 173
L+A D + N+ S + +EY V T+DG+IL L + + +N K V +
Sbjct: 26 LTAVDPETNMNVSEIISYWGFPSEEYLVETEDGYILCLNRIPHGRKNHSDKGPKPVVFLQ 85
Query: 174 HXXXXXXXX-XXXXXXXXXAYYMHDSGYDVWLGNNRCGFNSKWDRE----KLTPNGEWDW 228
H + + D+G+DVW+GN+R + W R+ ++ + W +
Sbjct: 86 HGLLADSSNWVTNLANSSLGFILADAGFDVWMGNSR---GNTWSRKHKTLSVSQDEFWAF 142
Query: 229 DLDSMTRYDLEALIESVLQKKQNKFEKLTLVAHSQGTTQAFMGLVNGEEIYKNTE--FRL 286
D M +YDL A I +L K E++ V HSQGTT F+ E+ K + F L
Sbjct: 143 SYDEMAKYDLPASINFILNKTGQ--EQVYYVGHSQGTTIGFIAFSQIPELAKRIKMFFAL 200
Query: 287 SDKLDNLVALAPAVYPGPLLDEKYFVKFMAKHIDNRWVFGNKSFVPMMMEMRNL---LAG 343
+P G L D + +K + FG+K F+P ++ L +
Sbjct: 201 GPVASVAFCTSPMAKLGRLPD--HLIKDL---------FGDKEFLPQSAFLKWLGTHVCT 249
Query: 344 HKIFSFLSYVMFNYLFNWNDILWDRPLRDRHFLFSPVHISVKLMQWWLSLNPLKSSFKTF 403
H I L + L +N+ + D + SP SV+ M W + F+ F
Sbjct: 250 HVILKELCGNLCFLLCGFNERNLNMSRVDVYTTHSPAGTSVQNMLHWSQAVKFQ-KFQAF 308
Query: 404 AEDMFPDIKTWFPIQNETVSMDEHLHRNQHKPLPENWPKIL----LFTPRQDRLVDGERL 459
D K +F H NQ P N +L +++ D L D +
Sbjct: 309 --DWGSSAKNYF-------------HYNQSYPPTYNVKDMLVPTAVWSGGHDWLADVYDV 353
Query: 460 ------INHFINHEPHSVYKIWYIDEYSHLDVLWASDVIERIGNPMLAHLR 504
I + + HE I E+ HLD +W D R+ N ++ +R
Sbjct: 354 NILLTQITNLVFHES--------IPEWEHLDFIWGLDAPWRLYNKIINLMR 396
>CE29647 [I] KOG2624 Triglyceride lipase-cholesterol esterase
Length = 351
Score = 73.6 bits (179), Expect = 7e-13
Identities = 65/223 (29%), Positives = 97/223 (43%), Gaps = 32/223 (14%)
Query: 141 YEVTTKDGFILELWHLRNENEGKTNTKYP------VLMLHXXXXXXXXXXXXXXXXXAYY 194
Y V T DG+ILE+ + GKTN +P V M H A +
Sbjct: 43 YTVATDDGYILEMHRIPF---GKTNVTWPNGKRPVVFMQHGLLCASSDWVVNLPDQSAGF 99
Query: 195 MH-DSGYDVWLGNNRCG-FNSKWDREKLTPNGEWDWDLDSMTRYDLEALIESVLQKKQNK 252
+ D+G+DVWLGN R ++ K K + + WDW D M YDL A+I VL+
Sbjct: 100 LFADAGFDVWLGNMRGNTYSMKHKDLKPSHSAFWDWSWDEMATYDLNAMINHVLEVTGQ- 158
Query: 253 FEKLTLVAHSQGTTQAFMGLVNGEEIYKNTEFRLSDKLDNLVALAPAVYPGPLLDEKYFV 312
+ + + HSQGT F L + + + K+ ALAP G + K F+
Sbjct: 159 -DSVYYMGHSQGTLTMFSHLSKDDGSF-------AKKIKKFFALAPI---GSVKHIKGFL 207
Query: 313 KFMAKHID---NRW--VFGNKSFVP----MMMEMRNLLAGHKI 346
F A + + W +FG F+P M + +++ G K+
Sbjct: 208 SFFANYFSLEFDGWFDIFGAGEFLPNNWAMKLAAKDICGGLKV 250
>CE18444 [I] KOG2624 Triglyceride lipase-cholesterol esterase
Length = 403
Score = 73.6 bits (179), Expect = 7e-13
Identities = 65/223 (29%), Positives = 97/223 (43%), Gaps = 32/223 (14%)
Query: 141 YEVTTKDGFILELWHLRNENEGKTNTKYP------VLMLHXXXXXXXXXXXXXXXXXAYY 194
Y V T DG+ILE+ + GKTN +P V M H A +
Sbjct: 43 YTVATDDGYILEMHRIPF---GKTNVTWPNGKRPVVFMQHGLLCASSDWVVNLPDQSAGF 99
Query: 195 MH-DSGYDVWLGNNRCG-FNSKWDREKLTPNGEWDWDLDSMTRYDLEALIESVLQKKQNK 252
+ D+G+DVWLGN R ++ K K + + WDW D M YDL A+I VL+
Sbjct: 100 LFADAGFDVWLGNMRGNTYSMKHKDLKPSHSAFWDWSWDEMATYDLNAMINHVLEVTGQ- 158
Query: 253 FEKLTLVAHSQGTTQAFMGLVNGEEIYKNTEFRLSDKLDNLVALAPAVYPGPLLDEKYFV 312
+ + + HSQGT F L + + + K+ ALAP G + K F+
Sbjct: 159 -DSVYYMGHSQGTLTMFSHLSKDDGSF-------AKKIKKFFALAPI---GSVKHIKGFL 207
Query: 313 KFMAKHID---NRW--VFGNKSFVP----MMMEMRNLLAGHKI 346
F A + + W +FG F+P M + +++ G K+
Sbjct: 208 SFFANYFSLEFDGWFDIFGAGEFLPNNWAMKLAAKDICGGLKV 250
>CE05874 [I] KOG2624 Triglyceride lipase-cholesterol esterase
Length = 411
Score = 72.8 bits (177), Expect = 1e-12
Identities = 63/225 (28%), Positives = 99/225 (44%), Gaps = 23/225 (10%)
Query: 119 EDLKLVPNLQYYYSQYNIIIDEYEVTTKDGFILELWHLRNENEGKT--NTKYPVLMLHXX 176
+D +L N ++ + + VTT+DG+IL++ + T N K PV++L
Sbjct: 27 DDPELNMNTSQIIERWGYKAEVHTVTTEDGYILQMQRIPYGKTSVTWPNGKRPVILLQHG 86
Query: 177 XXXXXXXXXXX--XXXXAYYMHDSGYDVWLGNNRCGFNSKWDREKLTPN--GEWDWDLDS 232
A+ D+G+DVWLGN R G KL P+ W + D
Sbjct: 87 LLACASDWVDNLPTQSAAFVFADAGFDVWLGNVR-GTTYGRKNTKLDPSETAFWQFSWDE 145
Query: 233 MTRYDLEALIESVLQKKQNKFEKLTLVAHSQGTTQAFMGLVNGEEIYKNTEFRLSDKLDN 292
M +YD+ A+++ VL E L + HSQGT F L K+T+ + K+
Sbjct: 146 MAQYDVPAMVDHVLAMTGQ--ENLYYMGHSQGTLIMFTHLA------KDTDGSFAKKIKR 197
Query: 293 LVALAPAVYPGPLLDEKYFVKFMAKHIDNRW-----VFGNKSFVP 332
ALAP G + + K F+ + A + +FG+K F+P
Sbjct: 198 YFALAPI---GAVKNIKGFLSYFAHKFSPEFDGWYELFGSKDFLP 239
>Hs17489494_2 [I] KOG2624 Triglyceride lipase-cholesterol esterase
Length = 348
Score = 72.0 bits (175), Expect = 2e-12
Identities = 46/113 (40%), Positives = 61/113 (53%), Gaps = 17/113 (15%)
Query: 192 AYYMHDSGYDVWLGNNRCGFNSKWDRE--KLTPNGE--WDWDLDSMTRYDLEALIESVLQ 247
A+ + DSGYDVWLGN+R + W R+ KL+P W + LD M +YDL A I +++
Sbjct: 20 AFLLADSGYDVWLGNSR---GNTWSRKHLKLSPKSPEYWAFSLDEMAKYDLPATINFIIE 76
Query: 248 KKQNKFEKLTLVAHSQGTTQAFMGLVNGEEIYKNTEFRLSDKLDNLVALAPAV 300
K K +L V HSQGTT AF+ E+ K K+ ALAP V
Sbjct: 77 KTGQK--RLYYVGHSQGTTIAFIAFSTNPELAK--------KIKIFFALAPVV 119
>Hs22055273 [I] KOG2624 Triglyceride lipase-cholesterol esterase
Length = 430
Score = 71.2 bits (173), Expect = 3e-12
Identities = 52/167 (31%), Positives = 80/167 (47%), Gaps = 20/167 (11%)
Query: 139 DEYEVTTKDGFILELWHLRNE--NEGKTNTKYPVLMLHXXXXXXXXXXXXX-XXXXAYYM 195
+EYEV T+DG+IL + + KT ++ VL+ H + +
Sbjct: 61 EEYEVATEDGYILSVNRIPRGLVQPKKTGSRPVVLLQHGLVGGASNWISNLPNNSLGFIL 120
Query: 196 HDSGYDVWLGNNRCGFNSKWDREKLTPNGE----WDWDLDSMTRYDLEALIESVLQKKQN 251
D+G+DVW+GN+R + W R+ T + + W + D M R+DL A+I +LQK
Sbjct: 121 ADAGFDVWMGNSR---GNAWSRKHKTLSIDQDEFWAFSYDEMARFDLPAVINFILQKTGQ 177
Query: 252 KFEKLTLVAHSQGTTQAFMGLVNGEEIYKNTEFRLSDKLDNLVALAP 298
EK+ V +SQGTT F+ +T L+ K+ ALAP
Sbjct: 178 --EKIYYVGYSQGTTMGFIAF--------STMPELAQKIKMYFALAP 214
>7297743 [I] KOG2624 Triglyceride lipase-cholesterol esterase
Length = 439
Score = 70.1 bits (170), Expect = 8e-12
Identities = 56/184 (30%), Positives = 83/184 (44%), Gaps = 24/184 (13%)
Query: 132 SQYNIIIDEYEVTTKDGFILELWHLRNENEGKTNTKYPVLMLHXXXXXXXXXXXXX-XXX 190
++Y + + VTT+DG+IL + +R + P L+ H
Sbjct: 73 AKYGYESEVHHVTTEDGYILTMHRIRKQGAP------PFLLQHGLVDSSAGFVVMGPNVS 126
Query: 191 XAYYMHDSGYDVWLGNNRCGFNSKWDREKLTPNGE----WDWDLDSMTRYDLEALIESVL 246
AY + D YDVWLGN R +++ R T + + WD+ + YDL A+I+ VL
Sbjct: 127 LAYLLADHNYDVWLGNAR---GNRYSRNHTTLDPDESKFWDFSWHEIGMYDLPAMIDHVL 183
Query: 247 QKKQNKFEKLTLVAHSQGTTQAFMGLVNGEEIYKNTEFRLSDKLDNLVALAPAVYPGPLL 306
K F KL HSQG T F+ + + Y +DK+ ++ ALAPAVY
Sbjct: 184 --KVTGFPKLHYAGHSQGCTSFFV-MCSMRPAY-------NDKVVSMQALAPAVYAKETE 233
Query: 307 DEKY 310
D Y
Sbjct: 234 DHPY 237
>7297734 [I] KOG2624 Triglyceride lipase-cholesterol esterase
Length = 456
Score = 68.6 bits (166), Expect = 2e-11
Identities = 49/174 (28%), Positives = 81/174 (46%), Gaps = 24/174 (13%)
Query: 133 QYNIIIDEYEVTTKDGFILELWHLRNENEGKTNTKYPVLMLHXXXXXXXXXXXXX-XXXX 191
+Y + + V TKDG+ILE+ + + PVL++H
Sbjct: 11 KYGYPSETHTVVTKDGYILEMHRIPKKGA------QPVLLMHGILDTSATWVLMGPKSGL 64
Query: 192 AYYMHDSGYDVWLGNNRCGFNSKWDREKLTPNGE----WDWDLDSMTRYDLEALIESVLQ 247
Y + D GYDVW+GN+R +++ + + N + WD+ M +YDL A I+ +L
Sbjct: 65 GYMLSDLGYDVWMGNSR---GNRYSKNHTSLNSDYQEFWDFTFHEMGKYDLPANIDYILS 121
Query: 248 KKQNKFEKLTLVAHSQGTTQAFMGLVNGEEIYKNTEFRLSDKLDNLVALAPAVY 301
K +E++ + HSQGT F L + + Y + K+ ++ ALAP Y
Sbjct: 122 K--TGYEQVHYIGHSQGTA-IFWVLCSEQPAY-------TQKITSMHALAPIAY 165
>7297722 [I] KOG2624 Triglyceride lipase-cholesterol esterase
Length = 406
Score = 68.2 bits (165), Expect = 3e-11
Identities = 103/403 (25%), Positives = 162/403 (39%), Gaps = 57/403 (14%)
Query: 119 EDLKLV-PNLQYYYSQYNIIIDEYEVTTKDGFILELWHLRNENEGKTNTKYPVLMLHXXX 177
ED L+ P+L +Y + +++ KDGF+L + PVL++H
Sbjct: 37 EDANLITPDL---IKKYGYPAETHKIQAKDGFVLTAHRIPKPGG------QPVLLVHGLL 87
Query: 178 XXXXXXXXXX-XXXXAYYMHDSGYDVWLGNNRCG-FNSKWDREKLTPNGEWDWDLDSMTR 235
+ + D GYDVWL N R ++ K R WD+ +
Sbjct: 88 DSSVAYVILGPERSLGFLLSDMGYDVWLLNTRGNRYSRKHKRYHRYQPQFWDFSFHELGV 147
Query: 236 YDLEALIESVLQKKQNKFEKLTLVAHSQGTTQAFMGLVNGEEIYKNTEFRLSDKLDNLVA 295
YDL A I+ VL + ++ FE++ V HSQGTT F V G E K+ + A
Sbjct: 148 YDLPAAIDYVLARSKD-FEQIHYVGHSQGTTSFF---VMGSE-----RSAYMKKIKLMQA 198
Query: 296 LAPAVY----PGPLLDEKYFVKFMAKHIDNRWVFGNKSFVPMMMEMRNLLAGHKIFSFLS 351
LAP V+ P++ FVK++ + FG F P R+L+ HKI SF+
Sbjct: 199 LAPVVFWDYIDSPII--LTFVKYLRPLVFIARSFGIYEFPPENEVWRSLI--HKICSFVF 254
Query: 352 YVMFNYLF---------NWNDILWDRPLRDRHFLFSPVHISVKLMQWWLSLNPLKSSFKT 402
Y +N L PL H + SVK ++ + FK
Sbjct: 255 QNTCTYFLMEAMGVDYAQFNSSL--LPLFTGH---ASSGSSVKSLEHYGQQIHSGGFFK- 308
Query: 403 FAEDMFPDIKTWFPIQNETVSMDEHLHRNQHKPLPENWPKILLFTPRQDRLVDGERLINH 462
+ TW +N V Q+K L K+ L+ R DRL + ++
Sbjct: 309 -----YNYYSTWENRRNHGVDTPP-----QYK-LTNVDCKVALYYSRNDRLTSDKDVV-R 356
Query: 463 FINHEPHSVYKIWYIDE-YSHLDVLWASDVIERIGNPMLAHLR 504
+ P+ V + D Y+H++ +W +DV + + M+ +R
Sbjct: 357 LRDILPNVVLDYMFPDPLYNHINFIWGNDVKTVLNDRMIELMR 399
>SPBC14C8.15 [I] KOG2624 Triglyceride lipase-cholesterol esterase
Length = 460
Score = 67.8 bits (164), Expect = 4e-11
Identities = 49/174 (28%), Positives = 85/174 (48%), Gaps = 22/174 (12%)
Query: 138 IDEYEVTTKDGFILELWHLRNENEGKT---NTKYPVLMLHXXXXXXXXXXXXXXXXXA-- 192
++E+ V T DG++L L + + +GK N PVL +H A
Sbjct: 86 LEEHFVRTTDGYLLGLHRVYKKKKGKIEELNYLPPVLFIHGLMMNSESWVCNLKKEDAIP 145
Query: 193 YYMHDSGYDVWLGNNRCGFNSKWDREKLTPNGE----WDWDLDSMTRYDLEALIESVLQK 248
+ + + GYDVWLGN R +K+ + + + + WD+ LDS+ +D+ ++++ +L
Sbjct: 146 FALVEQGYDVWLGNLR---GNKYSIKNIKFSSQNPKFWDFSLDSIAIFDIPSIVKYIL-- 200
Query: 249 KQNKFEKLTLVAHSQGTTQAFMGLVNGEEIYKNTEFRLSDKLDNLVALAPAVYP 302
N F+ ++LV SQG AF L + + L + + +ALAPA+ P
Sbjct: 201 SVNSFDSISLVGFSQGAILAFAAL--------SIDTELRNSVRAFIALAPAIAP 246
>7297727 [I] KOG2624 Triglyceride lipase-cholesterol esterase
Length = 457
Score = 67.8 bits (164), Expect = 4e-11
Identities = 51/173 (29%), Positives = 79/173 (45%), Gaps = 21/173 (12%)
Query: 133 QYNIIIDEYEVTTKDGFILELWHLRNENEGKTNTKYPVLMLHXXXXXXXXXXXXX-XXXX 191
+Y + ++VTT D +IL L + PVL++H
Sbjct: 48 KYKHPAETHQVTTDDKYILTLHRIARPGAK------PVLLVHGLEDTSSTWIVMGPESGL 101
Query: 192 AYYMHDSGYDVWLGNNRCGFNSKWDREKLTPNGE---WDWDLDSMTRYDLEALIESVLQK 248
Y+++ +GYDVW+GN R SK KL PN + W + + YDL A+I+ VLQK
Sbjct: 102 GYFLYANGYDVWMGNVRGNRYSK-GHVKLNPNTDKSYWSFSWHEIGMYDLPAMIDGVLQK 160
Query: 249 KQNKFEKLTLVAHSQGTTQAFMGLVNGEEIYKNTEFRLSDKLDNLVALAPAVY 301
++KL+ HSQGTT F + ++ + K+ + ALAP +
Sbjct: 161 --TGYQKLSYFGHSQGTTSFF--------VMASSRPEYNAKIHLMSALAPVAF 203
>CE11708 [I] KOG2624 Triglyceride lipase-cholesterol esterase
Length = 411
Score = 65.5 bits (158), Expect = 2e-10
Identities = 56/195 (28%), Positives = 79/195 (39%), Gaps = 20/195 (10%)
Query: 113 SDILSAEDLKLVPNLQYYYSQYNIIIDEYEVTTKDGFILELWHLRNENEGKT----NTKY 168
S+ + DL+ + + ++ Y TTKDGFILEL + E T N
Sbjct: 22 SNYSKSVDLEFYLDTPELIKSWGYSVEIYNTTTKDGFILELHRIPYGREVPTSSDVNNSR 81
Query: 169 PVLMLHXXXXXXXXXXXXXX--XXXAYYMHDSGYDVWLGNNRCGFNSKWDREKLTPNGE- 225
PV+ L + D+G+DVWLGN R S+ L P+ +
Sbjct: 82 PVIFLQHGFLCSSFDWVANSPHQSAGFVFADAGFDVWLGNFRGNTYSR-KHVSLNPDKDP 140
Query: 226 --WDWDLDSMTRYDLEALIESVLQKKQNKFEKLTLVAHSQGTTQAFMGLVNGEEIYKNTE 283
WDW D ++ YDL A+I L+ E L S GT F L +T+
Sbjct: 141 KFWDWSWDQISEYDLPAMIGKALEISGQ--ESLYYTGFSLGTLTMFAKL--------STD 190
Query: 284 FRLSDKLDNLVALAP 298
+ S K+ ALAP
Sbjct: 191 PKFSRKIKKYFALAP 205
>Hs17489492 [I] KOG2624 Triglyceride lipase-cholesterol esterase
Length = 351
Score = 64.7 bits (156), Expect = 3e-10
Identities = 49/163 (30%), Positives = 74/163 (45%), Gaps = 18/163 (11%)
Query: 120 DLKLVPNLQYYYSQYNIII------DEYEVTTKDGFILELWHLR--NENEGKTNTKYPVL 171
DL+ N + + + III +EYEVTT+DG+IL + + + T + V
Sbjct: 52 DLENEVNPEVWMNTSEIIIYNGYPSEEYEVTTEDGYILLVNRIPYGRTHARSTGPRPVVY 111
Query: 172 MLHXXXXXXXX-XXXXXXXXXAYYMHDSGYDVWLGNNRCGFNSKWDREKLTPNGE----W 226
M H + + D+GYDVW+GN+R + W R T + W
Sbjct: 112 MQHALFADNAYWLENYANGSLGFLLADAGYDVWMGNSR---GNTWSRRHKTLSETDEKFW 168
Query: 227 DWDLDSMTRYDLEALIESVLQKKQNKFEKLTLVAHSQGTTQAF 269
+ D M +YDL +I+ ++ K EKL + HS GTT F
Sbjct: 169 AFSFDEMAKYDLPGVIDFIVNKTGQ--EKLYFIGHSLGTTIGF 209
>CE24406 [I] KOG2624 Triglyceride lipase-cholesterol esterase
Length = 401
Score = 64.7 bits (156), Expect = 3e-10
Identities = 54/199 (27%), Positives = 87/199 (43%), Gaps = 11/199 (5%)
Query: 132 SQYNIIIDEYEVTTKDGFILELWHL---RNENEGKTNTKYPVLM-LHXXXXXXXXXXXXX 187
S Y ++++ VTT DG+ ++L + R++ +K PV+ +H
Sbjct: 30 SHYGYTVEKHYVTTDDGYTVQLQRIPVGRDDRSILGCSKRPVVFFMHGLFGSSYHFLLNL 89
Query: 188 -XXXXAYYMHDSGYDVWLGNNRCGFNSKWDREKLTPNGE--WDWDLDSMTRYDLEALIES 244
AY D+G+DVWLGN R G + + NG W++ L + YDL IE
Sbjct: 90 PSQSAAYIFADAGFDVWLGNIR-GTEYGLNHTSFSTNGVNFWNFSLYEHSHYDLRQQIEY 148
Query: 245 VLQKKQNKFEKLTLVAHSQGTTQAFMGLVNGEEIYKNTEFRLSDKLDNLVALAPAVYPGP 304
VL + E L V HSQGT F L + ++ ++ R+ L + P
Sbjct: 149 VLD--YTRHESLFYVGHSQGTAVMFARLAEADVTWQ-SKIRVFFALGPTAGFMKPLMPFT 205
Query: 305 LLDEKYFVKFMAKHIDNRW 323
LL+E Y + +D ++
Sbjct: 206 LLEENYLQALIQFALDGKF 224
>CE26551 [I] KOG2624 Triglyceride lipase-cholesterol esterase
Length = 684
Score = 63.9 bits (154), Expect = 5e-10
Identities = 57/196 (29%), Positives = 83/196 (42%), Gaps = 22/196 (11%)
Query: 111 PFSDILSAEDLKLVPNLQYYYSQYNIIIDEYEVTTKDGFILELW---HLRNE-NEGKTNT 166
P + + E L VP + + + ++ ++V T DG+IL L H +NE ++ + T
Sbjct: 264 PLNITIDPEALMDVPEI---ITHWGYPVETHKVVTVDGYILTLHRIPHGKNETSKSASKT 320
Query: 167 KYPVLMLHXXXXXXXXXXXXXX--XXXAYYMHDSGYDVWLGNNRCGFNSKWDREKLTPNG 224
PV+ L Y D GYDVWLGN R SK + ++T
Sbjct: 321 PKPVVFLQHGLLCTSSIWLLNLPRQSAGYIFADQGYDVWLGNMRGNTYSK-EHTRMTSAD 379
Query: 225 E--WDWDLDSMTRYDLEALIESVLQKKQNKFEKLTLVAHSQGTTQAFMGLVNGEEIYKNT 282
W + + M RYDL A+I L K K + L V HSQG F + E
Sbjct: 380 RRFWKFSWEEMARYDLPAMINYAL--KTTKRQNLYYVGHSQGALTMFAKMSEDPE----- 432
Query: 283 EFRLSDKLDNLVALAP 298
+S K+ A+AP
Sbjct: 433 ---MSKKIRKFFAMAP 445
>7303096 [I] KOG2624 Triglyceride lipase-cholesterol esterase
Length = 398
Score = 62.8 bits (151), Expect = 1e-09
Identities = 45/138 (32%), Positives = 68/138 (48%), Gaps = 9/138 (6%)
Query: 138 IDEYEVTTKDGFILELWHLR-NENEGKTNTKYPVLMLHXXXXXXXXXXXXX-XXXXAYYM 195
I+E+EV T DG+IL + + ++N G + V ++H AY +
Sbjct: 42 IEEHEVQTSDGYILTMHRIPYSKNTGYDGPRPVVFLMHGLLCSSSDWVLAGPHSGLAYLL 101
Query: 196 HDSGYDVWLGNNRCGFNSKWDREK---LTPNGEWDWDLDSMTRYDLEALIESVLQKKQNK 252
++GYDVW+GN R SK K L P W+++ + YDL A+++ VL
Sbjct: 102 SEAGYDVWMGNARGNTYSKRHASKSPLLQP--FWNFEWHDIGIYDLPAMMDYVLY--WTN 157
Query: 253 FEKLTLVAHSQGTTQAFM 270
+LT V HSQGTT F+
Sbjct: 158 VTQLTYVGHSQGTTSFFV 175
>7301402 [I] KOG2624 Triglyceride lipase-cholesterol esterase
Length = 838
Score = 62.0 bits (149), Expect = 2e-09
Identities = 45/182 (24%), Positives = 82/182 (44%), Gaps = 13/182 (7%)
Query: 125 PNLQYYYSQYNIIIDEYEVTTKDGFILELWHLR-NENEGKTNTKYPVLMLHXXXXXXXXX 183
P+ ++ ++ ++ + VTT+DG+I+ L+ + + N K P+ +
Sbjct: 53 PDTIHFIEEHGYPVERHYVTTEDGYIISLFRIPYSHNIQNQQEKRPIAFIQHGLFASSDF 112
Query: 184 --XXXXXXXXAYYMHDSGYDVWLGNNRCGFNSKWDREKLTPNGE-WDWDLDSMTRYDLEA 240
+ + D+GYDVWLGN R SK +LT + + W + + +D+ A
Sbjct: 113 WPSLGPDDGLPFLLSDAGYDVWLGNARGNRYSKNHTSRLTSHPDFWRFSWHEIGYFDIAA 172
Query: 241 LIESVLQKKQNKFEK-LTLVAHSQGTTQAFMGLVNGEEIYKNTEFRLSDKLDNLVALAPA 299
I+ L + + +K + + HSQGTT F+ L + E +DK+ LAP
Sbjct: 173 AIDYTLSTENGQDQKGIHYIGHSQGTTVMFVLLSSRPE--------YNDKIKTAHMLAPV 224
Query: 300 VY 301
+
Sbjct: 225 AF 226
Score = 51.2 bits (121), Expect = 4e-06
Identities = 51/209 (24%), Positives = 93/209 (44%), Gaps = 31/209 (14%)
Query: 139 DEYEVTTKDGFILELWH------LRNENEGKTNTKYPVLMLHXXXXXXXXXXXXXXXXXA 192
+ + + T+DG+IL ++ L+N+NE K P+++L
Sbjct: 477 EHHHIVTEDGYILGVFRIPYSHKLQNQNE-----KRPIVLLQHGLTSCSDAWILQGPNDG 531
Query: 193 --YYMHDSGYDVWLGNNRCGFNSKWDREKLTPN--GEWDWDLDSMTRYDLEALIESVLQK 248
Y + D+G+DVW+GN R G + + L+P+ W + + YD+ A+I+ L
Sbjct: 532 LPYLLADAGFDVWMGNAR-GTSYSRNHTTLSPDHPNFWKFSWHEIGIYDITAIIDYALST 590
Query: 249 KQNK-FEKLTLVAHSQGTTQAFMGLVNGEEIYKNTEFRLSDKLDNLVALAPAVYPGPLLD 307
+ + + + V HSQGTT F L++ Y +DK+ AP L
Sbjct: 591 ENGQGQDAIHYVGHSQGTT-VFFALMSWIPEY-------NDKIKTAHMFAPVAIMKNL-- 640
Query: 308 EKYFVKFMAKHIDNR----WVFGNKSFVP 332
V+ + ++ +R +FG++ F+P
Sbjct: 641 SSGLVRSVGPYLGHRNTYSVLFGSQEFLP 669
>7302156 [I] KOG2624 Triglyceride lipase-cholesterol esterase
Length = 342
Score = 61.6 bits (148), Expect = 3e-09
Identities = 51/177 (28%), Positives = 85/177 (47%), Gaps = 27/177 (15%)
Query: 197 DSGYDVWLGNNRCGFNSKWDREKLTPNGE--WDWDLDSMTRYDLEALIESVLQKKQNKFE 254
D+GYDVWLGN R S+ + + P+ W + + YDL A+++ L K Q+
Sbjct: 4 DAGYDVWLGNARGNTYSR-QHKHIHPDTSDFWRFSWHEIGVYDLAAMLDYALAKSQS--S 60
Query: 255 KLTLVAHSQGTTQAFMGLVNGEEIYKNTEFRLSDKLDNLVALAPAVYPGPLLDEKYFVK- 313
L VAHSQGTT AF L++ +Y ++KL ++ LAP Y + D + +
Sbjct: 61 SLHFVAHSQGTT-AFFVLMSSLPLY-------NEKLRSVHLLAPIAY---MRDHSFILSK 109
Query: 314 ----FMAKHIDNRWVFGNKSFVPMMMEMRNLLAGH-----KIFSFLSYVMFNYLFNW 361
F+ WV G+ +P + ++ L+ H +F+FL + +++ W
Sbjct: 110 LGGIFLGTPSFLSWVLGSMELLP-ITNLQKLICEHICSSSSMFNFLCSGLLDFIGGW 165
>7296316 [I] KOG2624 Triglyceride lipase-cholesterol esterase
Length = 399
Score = 60.8 bits (146), Expect = 5e-09
Identities = 42/136 (30%), Positives = 67/136 (48%), Gaps = 14/136 (10%)
Query: 139 DEYEVTTKDGFILELWH------LRNENEGKTNTKYPVLMLHXXXXXXXXXXXXX-XXXX 191
+ +EVTT+DG++L L+ L+N+NE + P+L+ H
Sbjct: 44 ETHEVTTQDGYVLTLFRIPYSHKLKNQNEKRP----PILLQHGLFSNSDCWLSSGPDNSL 99
Query: 192 AYYMHDSGYDVWLGNNRCGFNSKWD-REKLTPNGEWDWDLDSMTRYDLEALIESVLQKKQ 250
AY + D+GYDVWLGN R S+ + L + W +D + D+ A+I+ +L
Sbjct: 100 AYLLADAGYDVWLGNARGNIYSRNNIIISLNSHKFWHFDWHEIGTIDIPAMIDYIL--AD 157
Query: 251 NKFEKLTLVAHSQGTT 266
F+++ HSQGTT
Sbjct: 158 TGFDQIHYAGHSQGTT 173
>7299754 [I] KOG2624 Triglyceride lipase-cholesterol esterase
Length = 394
Score = 59.7 bits (143), Expect = 1e-08
Identities = 49/171 (28%), Positives = 78/171 (44%), Gaps = 17/171 (9%)
Query: 138 IDEYEVTTKDGFILELWHLRNENEGKTNTKYPV--LMLHXXXXXXXXXXXXXXXXXAYYM 195
++ +EV T D +IL + + + ++ PV LM AY +
Sbjct: 39 MERHEVVTSDNYILTMHRIPYSPKTGESSNRPVAFLMHGMLSSSSDWVLMGPERSLAYML 98
Query: 196 HDSGYDVWLGNNRCGFNSKWDREKLTPNG---EWDWDLDSMTRYDLEALIESVLQKKQNK 252
D+GYDVW+GN R SK K P W++ + + YD+ A+I+ VL K
Sbjct: 99 ADAGYDVWMGNARGNTYSK--AHKYWPTYWQIFWNFSWNEIGMYDVPAMIDYVLAKTGQ- 155
Query: 253 FEKLTLVAHSQGTTQAFMGLVNGEEIYKNTEFRLSDKLDNLVALAPAVYPG 303
+++ V HSQGTT ++ +V+ Y +DK+ + L PA Y G
Sbjct: 156 -QQVQYVGHSQGTT-VYLVMVSERPEY-------NDKIKSAHLLGPAAYMG 197
>At2g15230 [I] KOG2624 Triglyceride lipase-cholesterol esterase
Length = 344
Score = 57.8 bits (138), Expect = 4e-08
Identities = 47/185 (25%), Positives = 78/185 (41%), Gaps = 21/185 (11%)
Query: 135 NIIIDEYEVTTKDGFILELWHLRNENEGKTNTKYPVLMLHXXXXXXXXXXXXX-XXXXAY 193
N E+ + TKDG+IL L + + + + PVL+ H +
Sbjct: 41 NYSCTEHSIQTKDGYILALQRVASLGP-RLQSGPPVLLQHGLFMAGDVWFLNSPKESLGF 99
Query: 194 YMHDSGYDVWLGNNRCGFNSKWDREKLTPNGE--WDWDLDSMTRYDLEALIESVLQKKQN 251
+ D G+DVW+GN R G + L+ + WDW + YDL +I+ + +
Sbjct: 100 ILADHGFDVWVGNVR-GTRYSYGHVTLSDTDKEFWDWSWQDLAMYDLAEMIQYLYSISNS 158
Query: 252 KFEKLTLVAHSQGTTQAFMGLVNGEEIYKNTEFRLSDKLDNLVALAPAVY----PGPLLD 307
K+ LV HSQGT +F L T+ +++ ++ L P Y PL++
Sbjct: 159 ---KIFLVGHSQGTIMSFAAL---------TQPHVAEMVEAAALLCPISYLDHVTAPLVE 206
Query: 308 EKYFV 312
F+
Sbjct: 207 RMVFM 211
>7297730 [I] KOG2624 Triglyceride lipase-cholesterol esterase
Length = 356
Score = 57.0 bits (136), Expect = 7e-08
Identities = 59/220 (26%), Positives = 89/220 (39%), Gaps = 38/220 (17%)
Query: 132 SQYNIIIDEYEVTTKDGFILELWHLRNENEGKTNTKYPVLMLHXXXXXXXXXXXXX-XXX 190
S+Y ++ + T DG+ L L + G T PVL++H
Sbjct: 3 SKYGHQVETHYAFTADGYKLCLHRI--PRSGAT----PVLLVHGLMASSATWVQFGPSQG 56
Query: 191 XAYYMHDSGYDVWLGNNRCGFNSKWDREKLTPNGE----WDWDLDSMTRYDLEALIESVL 246
AY + SGYDVW+ N R + + E+L WD+ + +YDL A I+ +L
Sbjct: 57 LAYILSQSGYDVWMLNTR---GNVYSEERLAGRESDKIFWDFSFHEIGQYDLPAAIDLIL 113
Query: 247 QKKQNKFEKLTLVAHSQGTTQAFMGLVNGEEIYKNTEFRLSDKLDNLVALAPAVYPGPLL 306
Q K + + HSQG+T F+ E + K+ + +L+P+VY
Sbjct: 114 --LQTKMPSIQYIGHSQGSTAFFVMCSERPE--------YAGKISLMQSLSPSVYMEGTR 163
Query: 307 DEKYFVKFMAKHIDNRWVFGNKSFVPMMMEMRNLLAGHKI 346
+KFM K F + NLL GHKI
Sbjct: 164 SPA--LKFM------------KLFSGGFTMLLNLLGGHKI 189
>7299660 [I] KOG2624 Triglyceride lipase-cholesterol esterase
Length = 435
Score = 55.8 bits (133), Expect = 1e-07
Identities = 62/219 (28%), Positives = 95/219 (43%), Gaps = 23/219 (10%)
Query: 138 IDEYEVTTKDGFILELWHLRN-ENEGKTNTKYPVLMLHXXXXXXXXX--XXXXXXXXAYY 194
++ + VTTKDG++L L + + E + + PV+ L AY
Sbjct: 76 VERHSVTTKDGYVLTLHRIPQVDPELGSLLRRPVVFLLSGLYASSDVWLLNGREDSLAYL 135
Query: 195 MHDSGYDVWLGNNRCGFNSKWDREKLTPNGE-WDWDLDSMTRYDLEALIESVLQKKQNKF 253
+ +GYDVWLGNNR + + + T E WD+ M YDL A ++ VL+ K
Sbjct: 136 LWRAGYDVWLGNNRGNIYCRKNMWRNTTEREFWDFSWHEMGVYDLPAQVDYVLRTTGQK- 194
Query: 254 EKLTLVAHSQGTTQAFMGLVNGEEIYKNTEFRLSDKLDNLVALAPAVYPGPLLDEKYFVK 313
+ V SQG T F+ ++N N F+ + LAP Y
Sbjct: 195 -AMHFVGISQGGT-VFL-VLNSMMPQYNAVFK------SATLLAPVAYVSNTKSG----- 240
Query: 314 FMAKHIDNRWVFGNKSFVPMMMEMRNLLAGHKIF-SFLS 351
+AK I V G +++V M+E + + +K F FLS
Sbjct: 241 -LAKVIGP--VLGTRNYVSKMLEGVEMFSTNKFFKKFLS 276
>7295808 [I] KOG2624 Triglyceride lipase-cholesterol esterase
Length = 416
Score = 55.8 bits (133), Expect = 1e-07
Identities = 56/207 (27%), Positives = 85/207 (41%), Gaps = 26/207 (12%)
Query: 108 DFNPFSDILSAEDLKLVPNLQYYYSQYNIIIDEYEVTTKDGFILELWHL-------RNEN 160
DF+PF DI K + +++ + + V T DG++L ++ + N N
Sbjct: 20 DFDPFIDI----PFKRLKTSAERIAEHGYPAESHFVETPDGYVLNVFRIPHSPKLNSNGN 75
Query: 161 EGKTNTKYPVLMLHXXXXXXXXXXXXXXXXXA--YYMHDSGYDVWLGNNRCGFNSKWD-R 217
EG++ PV+++ A Y D+GYDVWLGN R S+ + R
Sbjct: 76 EGESEASRPVVLIMHGLFSCSDCFLLNGPEDALPYNYADAGYDVWLGNARGNIYSRNNTR 135
Query: 218 EKLTPNGEWDWDLDSMTRYDLEALIESVLQKKQNKFEKLTLVAHSQGTTQAF-MGLVNGE 276
+ W + + DL A I+ +L + + L V HSQG T F MG E
Sbjct: 136 LNVKHPYFWKFSWHEIGSIDLPATIDYILAETGQ--QSLHYVGHSQGCTSFFVMGSYRPE 193
Query: 277 EIYKNTEFRLSDKLDNLVALAPAVYPG 303
+ K+ LAP VY G
Sbjct: 194 ---------YNAKIKTAHMLAPPVYMG 211
>CE09169 [I] KOG2624 Triglyceride lipase-cholesterol esterase
Length = 426
Score = 53.1 bits (126), Expect = 1e-06
Identities = 61/261 (23%), Positives = 111/261 (42%), Gaps = 22/261 (8%)
Query: 143 VTTKDGFILELWHL---RNENEGKTNTKYPVLMLHXXXXXXXXXXXXXXXXXAYYMH-DS 198
V T D +ILEL + +NE +++ + V M H A ++ D+
Sbjct: 45 VRTTDEYILELHRIPCKQNEKCDRSSKRPIVFMQHGLLADGFSWIPNLANQSAGFVFADA 104
Query: 199 GYDVWLGNNRCGFNSKWDREKLTPNGE--WDWDLDSMTRYDLEALIESVLQKKQNKFEKL 256
G+D+W+ N+R G + P + W++ M+ +DL A ++ VL K+ K E L
Sbjct: 105 GFDIWIANSR-GTPASQKHIGYGPENQKFWNFTWQQMSEFDLTASVDLVL--KETKQEFL 161
Query: 257 TLVAHSQGTTQAFMGLVNGEEIYKNTEFRLSDKLDNLVALAPAVYPGPL--LDEKYFVKF 314
+ HSQGT F L E K K+ + ALAP + L + KF
Sbjct: 162 YYLGHSQGTMIMFSRLAENPEFAK--------KIRHFHALAPVATVSHIGGLFGLFGTKF 213
Query: 315 M--AKHIDNRWVFGNKSFVPMMMEMRNLLAGHKIFSFLSYVMFNYLFNWNDILWDRPLRD 372
+ A+ + R + S + +M + + + + ++ + N+ ++++
Sbjct: 214 LTYAEILLGRLPYSPLSIPRTVQKMISYMCSRFFMQNICTLDIGFI-DGNEKMFNQSRVG 272
Query: 373 RHFLFSPVHISVKLMQWWLSL 393
+ +P SVK +Q W+ L
Sbjct: 273 VYLCHTPAATSVKDLQHWIQL 293
>7297731 [I] KOG2624 Triglyceride lipase-cholesterol esterase
Length = 318
Score = 52.4 bits (124), Expect = 2e-06
Identities = 32/111 (28%), Positives = 55/111 (48%), Gaps = 11/111 (9%)
Query: 192 AYYMHDSGYDVWLGNNRCGFNSKWD-REKLTPNGEWDWDLDSMTRYDLEALIESVLQKKQ 250
AY ++ GYDVW+ N R S+ + +L PN WD+ + ++D+ A I+ +L
Sbjct: 17 AYILYRKGYDVWMLNTRGNIYSRENLNRRLKPNKYWDFSFHEIGKFDVPAAIDHILIHTH 76
Query: 251 NKFEKLTLVAHSQGTTQAFMGLVNGEEIYKNTEFRLSDKLDNLVALAPAVY 301
K+ + HSQG+T F + + + K++ + AL+P VY
Sbjct: 77 K--PKIQYIGHSQGSTVFF--------VMCSERPNYAHKVNLMQALSPTVY 117
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.323 0.138 0.441
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,032,462
Number of Sequences: 60738
Number of extensions: 1396848
Number of successful extensions: 2999
Number of sequences better than 1.0e-05: 34
Number of HSP's better than 0.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 32
Number of HSP's that attempted gapping in prelim test: 2895
Number of HSP's gapped (non-prelim): 47
length of query: 512
length of database: 30,389,216
effective HSP length: 111
effective length of query: 401
effective length of database: 23,647,298
effective search space: 9482566498
effective search space used: 9482566498
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)