ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI4270 suspect: %id S KOG1408 Function unknown WD40 repeat protein
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI4270 1490063 1487478 -862
(862 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
Hs22057360 [S] KOG1408 WD40 repeat protein 109 2e-23
7296030_1 [S] KOG1408 WD40 repeat protein 56 3e-07
CE28482 [S] KOG1408 WD40 repeat protein 53 2e-06
>Hs22057360 [S] KOG1408 WD40 repeat protein
Length = 1514
Score = 109 bits (273), Expect = 2e-23
Identities = 150/675 (22%), Positives = 284/675 (41%), Gaps = 110/675 (16%)
Query: 127 KDISCLCFSADAKFLIVGETGHQPRILLYSMAPDSNDFPVFVIHQHSYGISQLQFHPDDS 186
K I+ L FS D K+L+ GE+GH P + ++ +A S V + +H YG++ + F P
Sbjct: 91 KTITALAFSPDGKYLVTGESGHMPAVRVWDVAEHSQ---VAELQEHKYGVACVAFSPSAK 147
Query: 187 TIFTSLGLINDGFLHIWKLSTNSIRLVASNKNSTIVLGLNWYKD-SALVTYGVRQIKVWK 245
I S+G +D +++W N + VASNK S+ V +++ +D S VT G R IK W
Sbjct: 148 YI-VSVGYQHDMIVNVWAWKKNIV--VASNKVSSRVTAVSFSEDCSYFVTAGNRHIKFWY 204
Query: 246 FENTNNTANNKLTIPRTRTAIKGKNIVLGTLIESTFID---SEWLRDDQLLFLTDSRQVV 302
++ + T+ T+P + G++ +LG L + F D + D +T S +
Sbjct: 205 LDD-SKTSKVNATVP-----LLGRSGLLGELRNNLFTDVACGRGKKADSTFCITSSGLLC 258
Query: 303 LYQNGSLISLY-ELEGDKQYDNIL---VDWDNDKLWF------------SYDEYVDSIPL 346
+ + L+ + EL + + + D ++ S ++ ++P
Sbjct: 259 EFSDRRLLDKWVELRNIDSFTTTVAHCISVSQDYIFCGCADGTVRLFNPSNLHFLSTLPR 318
Query: 347 THVLNHQERLRPGSGSSSIRGASPIKNNLFDQKFVDTEA--------------------- 385
H L G+ +S+ AS + + + + ++ DT A
Sbjct: 319 PHAL--------GTDIASVTEASRLFSGVANARYPDTIALTFDPTNQWLSCVYNDHSIYV 370
Query: 386 -SVRDTHKI--LMMKLVTNKTVLFCTSKGEISIINETIKP----ISNPSLNDIKVFKK-- 436
VRD K+ + L + V E+ N+ P I+ S N I+++
Sbjct: 371 WDVRDPKKVGKVYSALYHSSCVWSVEVYPEVKDSNQACLPPSSFITCSSDNTIRLWNTES 430
Query: 437 ------------INNDLAVLCSKKGDIKLFDGTKL-SKYELDISDLSSDEEITSLDFSVN 483
+++DL + G+ + T+L + D S L I S+ S N
Sbjct: 431 SGVHGSTLHRNILSSDLIKIIYVDGNTQALLDTELPGGDKADASLLDPRVGIRSVCVSPN 490
Query: 484 ENYFVVGDSTGKLSVYKDNVCEYQSKV--HSAAINGIQIYEKD-AFKIVITISRDRTMNF 540
+ GD G L V++ KV H + I ++ + D K++ + SRDR ++
Sbjct: 491 GQHLASGDRMGTLRVHELQSLSEMLKVEAHDSEILCLEYSKPDTGLKLLASASRDRLIHV 550
Query: 541 IELRAGEWNICETVKDNKGNI--IQLEMCDNKLYTISSDRTVSCYRIDIVDNTLNVSKET 598
++ E+++ +T+ ++ +I ++ D ++ IS S Y T S +
Sbjct: 551 LD-AGREYSLQQTLDEHSSSITAVKFAASDGQVRMISCGADKSIY-----FRTAQKSGDG 604
Query: 599 ILSVKNSPLRLQLTNSDIIVSRS---------DKTMQIFDKTSNSTPXXXXXXXXQGDGI 649
+ + + + T D+ V S D+ ++IF+ +S + DG
Sbjct: 605 VQFTRTHHVVRKTTLYDMDVEPSWKYTAIGCQDRNIRIFNISSGKQKKLFKGSQGE-DGT 663
Query: 650 LVNHFYVNADSDQI-LCSSSLDKTIRCFSYTTGKCLNQYYAHADPVVGM--TTVANKFVT 706
L+ V D I + +S DK + F +++G+C+ + H++ V GM + ++
Sbjct: 664 LIK---VQTDPSGIYIATSCSDKNLSIFDFSSGECVATMFGHSEIVTGMKFSNDCKHLIS 720
Query: 707 VTGNGCLFSWEIRPE 721
V+G+ C+F W + E
Sbjct: 721 VSGDSCIFVWRLSSE 735
>7296030_1 [S] KOG1408 WD40 repeat protein
Length = 793
Score = 55.8 bits (133), Expect = 3e-07
Identities = 57/307 (18%), Positives = 131/307 (42%), Gaps = 44/307 (14%)
Query: 432 KVFKKINNDLAVLCSKKGDIKLFDGTKLSKYELDISDLSSDEEITSLDFSVNENYFVVGD 491
++ K + +D + K LFD S Y+ + + S + GD
Sbjct: 436 ELLKIVYSDDELQFIKDQGSSLFDKAGNSSYD-------GRNGVRCIKISPELQHLASGD 488
Query: 492 STGKLSVYKDNVCEYQSKVHSAAINGIQIYEKDAF-----------KIVITISRDRTMNF 540
G + VY S V+ + I+ +E + K++ + SRDR ++
Sbjct: 489 RCGNIRVY--------SLVNLRLLTTIEAHESEVLCLEYSNEKIERKLLASASRDRLIHV 540
Query: 541 IELRAGEWNICETVKDNKGNIIQLEMC----DNKLYTISSDRTVS--CYRIDIVDNTLNV 594
++ A + + +T+ D+ +I ++ + ++ + +D+++ ++ +I N
Sbjct: 541 FDV-AQNYLLLQTLDDHSSSITSIKFVGAGLNFQMISCGADKSIMFRSFQGNIFMRGTNT 599
Query: 595 SKETILSVKNSPLRLQLTNSDIIVSRSDKTMQIFDKTSNSTPXXXXXXXXQGDGILVNHF 654
S +T L + + I+ + D+ ++++ T N+ +G L+
Sbjct: 600 SGKTTLY----DMEVDSNAKHILTACQDRNVRVYG-TQNAKQTKTFKGSHSDEGSLIK-- 652
Query: 655 YVNADSDQI-LCSSSLDKTIRCFSYTTGKCLNQYYAHADPVVGM--TTVANKFVTVTGNG 711
++ D I + +S DKT+ + Y + +C+ + Y H++ V G+ T ++ +G+G
Sbjct: 653 -LSLDPSGIYVATSCTDKTLAVYDYYSNECMARMYGHSELVTGLKFTNDCRHLISASGDG 711
Query: 712 CLFSWEI 718
C+F W++
Sbjct: 712 CIFIWQV 718
>CE28482 [S] KOG1408 WD40 repeat protein
Length = 1693
Score = 53.1 bits (126), Expect = 2e-06
Identities = 50/252 (19%), Positives = 101/252 (39%), Gaps = 31/252 (12%)
Query: 100 EASEKAVTIGSDLSPARCSPSKIKDRIKDISCLCFSADAKFLIVGE-------------T 146
+ + ++ + S S R I + +C+ ++ K+ GE T
Sbjct: 46 QVAGSSIIVSSTASHDRFEGHLISQTKQQFTCVAVTSCGKYAATGEHFTVWENYSVVLQT 105
Query: 147 GHQPRILLYSMAPDSNDFP---VFVIHQHSYGISQLQFHPDDSTIFTSLGLINDGFLHIW 203
GHQP + L+ + +F V + H+ I+ ++F PDDST+ S+G +D + W
Sbjct: 106 GHQPAVRLWQLRDAQGNFVGRLVRSMQSHTVSITIVRFTPDDSTLI-SIGCQHDAQIFTW 164
Query: 204 KLSTNSIRLVASNKNSTIVLGLNWYKDSALVTYGVRQIKVWKFENTNNTANNKLTIPRTR 263
T V + L ++ + S VT G + +K W ++ N R
Sbjct: 165 DWRTGHDLGVGKLMSPVNALTIS-FDSSMCVTVGSKSVKYWFLPLASDGMNK-------R 216
Query: 264 TAIKGKNIVLGTLIESTFIDSEWL-RDDQLLFLTDSRQVVLYQNGSLISLYELEGDKQYD 322
T + ++ +L F+D+ + ++++ +T S +++ + +S Q+
Sbjct: 217 TGLTSRSAILADKRNVNFVDAAFCDSTNRMVTVTSSGEILEFNGNKKVSCV-----YQFK 271
Query: 323 NILVDWDNDKLW 334
N V + W
Sbjct: 272 NFFVQYVKCYTW 283
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.316 0.133 0.383
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 50,859,048
Number of Sequences: 60738
Number of extensions: 2232972
Number of successful extensions: 7337
Number of sequences better than 1.0e-05: 3
Number of HSP's better than 0.0 without gapping: 0
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 7330
Number of HSP's gapped (non-prelim): 7
length of query: 862
length of database: 30,389,216
effective HSP length: 115
effective length of query: 747
effective length of database: 23,404,346
effective search space: 17483046462
effective search space used: 17483046462
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)