ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI4407 good R KOG2121 General function prediction only Predicted metal-dependent hydrolase (beta-lactamase superfamily)
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI4407 1538124 1535659 -822
(822 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YKR079c [R] KOG2121 Predicted metal-dependent hydrolase (beta-la... 830 0.0
SPAC1D4.10 [R] KOG2121 Predicted metal-dependent hydrolase (beta... 244 3e-64
7303764 [R] KOG2121 Predicted metal-dependent hydrolase (beta-la... 212 2e-54
At3g16260 [R] KOG2121 Predicted metal-dependent hydrolase (beta-... 199 1e-50
At1g52160 [R] KOG2121 Predicted metal-dependent hydrolase (beta-... 196 9e-50
HsM11875213 [R] KOG2121 Predicted metal-dependent hydrolase (bet... 185 3e-46
Hs21359941 [R] KOG2121 Predicted metal-dependent hydrolase (beta... 184 4e-46
SPBC3D6.03c [R] KOG2121 Predicted metal-dependent hydrolase (bet... 122 2e-27
CE29248 [R] KOG2121 Predicted metal-dependent hydrolase (beta-la... 117 7e-26
ECU06g0440 [R] KOG2121 Predicted metal-dependent hydrolase (beta... 112 2e-24
>YKR079c [R] KOG2121 Predicted metal-dependent hydrolase (beta-lactamase
superfamily)
Length = 838
Score = 830 bits (2144), Expect = 0.0
Identities = 421/839 (50%), Positives = 588/839 (69%), Gaps = 31/839 (3%)
Query: 1 MYQLIPITHPCLDTKQPLLLLQSDHGDKYFFGKIGEGSQRACNESKVKFGKLNGIFLTGE 60
M+ IPITHP DTK PLLL+QS HG+KYFFGKIGEGSQR+ E+K++ KL IFLTGE
Sbjct: 1 MFTFIPITHPTSDTKHPLLLVQSAHGEKYFFGKIGEGSQRSLTENKIRISKLKDIFLTGE 60
Query: 61 MDYSCIGGLPGLILTASDQGKKDISIFYGSNILDYVVSTWRYFVFRFGLDLKVSTLKNSE 120
+++S IGGLPG+ILT +DQGK ++ + YG++IL+Y+VSTWRYFVFRFG+DL +K+ E
Sbjct: 61 LNWSDIGGLPGMILTIADQGKSNLVLHYGNDILNYIVSTWRYFVFRFGIDLNDHIMKDKE 120
Query: 121 CYQDSTITVKSIVISNSANVDQCVQQHQSLG----FTNG-LKNIIARMFPEVNPTDEQDP 175
Y+D I VKS + + D+ LG F G L++I+A+MFP+ PTD DP
Sbjct: 121 VYKDKIIAVKSFNVLKNGGEDR-------LGVFDSFQKGVLRSIVAKMFPKHAPTDRYDP 173
Query: 176 SANSTLNVDIPPEAIGAK-NLTTSYELTFPAVRGKFNVEEAKRLGVPKGRLYAELAKGNS 234
S++ LNV++P + AK ++T+YE++F VRGKF VEEA +LGVPKG L+A+L KG +
Sbjct: 174 SSDPHLNVELPD--LDAKVEVSTNYEISFSPVRGKFKVEEAIKLGVPKGPLFAKLTKGQT 231
Query: 235 ITLEDGTVINSDQVLSETRNFGKVLVLDIPSNKYIPRFIDEFKNYPTDQLSAIYYFLGDE 294
ITL++G V+ +QVL R+F KVL+LDIP + Y+ F+++FK+Y +L +YYFLGDE
Sbjct: 232 ITLDNGIVVTPEQVLENERHFAKVLILDIPDDLYLNAFVEKFKDYDCAELGMVYYFLGDE 291
Query: 295 VTITDDLFQFFDTFSDD---QIQHYVSHSSISPNTIAYESAAIATLKLKALQVESYNIPI 351
VTI D+LF F D F + ++ H +SH+ ISPNTI++ +A+ TLKLKALQV +YN+P
Sbjct: 292 VTINDNLFAFIDIFEKNNYGKVNHMISHNKISPNTISFFGSALTTLKLKALQVNNYNLPK 351
Query: 352 TDRVYSREFFHCFPKDLPEGSSLVQQQEHVPSCLVKNENMHVFEKMKGIALEPFTVGKEN 411
TDRV+S++F+ F L G+S+ + QE + +++ +N+H+F + K + EPF + +E
Sbjct: 352 TDRVFSKDFYDRFDTPLSRGTSMCKSQEEPLNTIIEKDNIHIFSQNKTVTFEPFRMNEEP 411
Query: 412 MVIHESQLPTAKQSSTIDELYESHVVPLCIEGSSLERTVHEQVHVNNFDNKT-KLNEIEI 470
M + + + E++E HV PL + ++ ++ Q+HV+NF+N K +EI
Sbjct: 412 M---KCNINGEVADFSWQEIFEEHVKPLEFPLADVDTVINNQLHVDNFNNSAEKKKHVEI 468
Query: 471 ISLGTGSALPSKYRNVISTLVKIPYTEVDGTVVNRSILLDAGENTLGTIHRTIPDIDVPK 530
I+LGTGSALPSKYRNV+STLVK+P+T+ DG +NR+I+LDAGENTLGTIHR + V
Sbjct: 469 ITLGTGSALPSKYRNVVSTLVKVPFTDADGNTINRNIMLDAGENTLGTIHRMFSQLAVKS 528
Query: 531 LFRDVKLIYLSHLHADHHLGIASLIKEWYKHNK-HTADKLYVITPWQYNIFVREWFSLED 589
+F+D+K+IYLSHLHADHHLGI S++ EWYK+NK +YV+TPWQY+ FV EW LE+
Sbjct: 529 IFQDLKMIYLSHLHADHHLGIISVLNEWYKYNKDDETSYIYVVTPWQYHKFVNEWLVLEN 588
Query: 590 PAILSRIEYISCEHLKAGDDIRKQTKPLSMD-----VDGTYATKGRKDLEHDEESAVKDT 644
IL RI+YISCEH +R QT+ + + + + + LE D +S+ +D
Sbjct: 589 KEILKRIKYISCEHFINDSFVRMQTQSVPLAEFNEILKENSNQESNRKLELDRDSSYRDV 648
Query: 645 AKIKKLMQNLRLMSFRTCPAIHCDWAYCNSISFFLSARSK-ELFKLSYSGDTRPNFNQFA 703
I+++ ++L + F+TC AIHCDWAY NSI+F + ++ FK+SYSGDTRPN +F+
Sbjct: 649 DLIRQMYEDLSIEYFQTCRAIHCDWAYSNSITFRMDENNEHNTFKVSYSGDTRPNIEKFS 708
Query: 704 RGIGKNSDLLIHEATLENELKVEAMKKRHSTINEAIKVSNTMNARKLLLTHFSQRYPKVP 763
IG NSDLLIHEATLEN+L +A+KK+H TINEAI VSN MNARKL+LTHFSQRYPK+P
Sbjct: 709 LEIGYNSDLLIHEATLENQLLEDAVKKKHCTINEAIGVSNKMNARKLILTHFSQRYPKLP 768
Query: 764 NTNRSIKLNARELCFAFDGMIVSFNELGKQQDKIDLLGSIFVEEENDAKKEDVKGLGNI 822
+ +I + ARE CFAFD MIV + ++G+QQ LL FVEE+ + +EDV + ++
Sbjct: 769 QLDNNIDVMAREFCFAFDSMIVDYEKIGEQQRIFPLLNKAFVEEKEE--EEDVDDVESV 825
>SPAC1D4.10 [R] KOG2121 Predicted metal-dependent hydrolase (beta-lactamase
superfamily)
Length = 809
Score = 244 bits (624), Expect = 3e-64
Identities = 230/877 (26%), Positives = 391/877 (44%), Gaps = 160/877 (18%)
Query: 5 IPITHPCLDTKQPLLLLQSDHGDKYFFGKIGEGSQRACNESKVKFGKLNGIFL------- 57
IP H D+K +Y FG +GEG QRA +++ K+ +FL
Sbjct: 28 IPCIHLFFDSK------------RYVFGSVGEGCQRAILSQQLRLSKIKDVFLMQGSSIS 75
Query: 58 -----------------------------TGEMDYSC-----------IGGLPGLILTAS 77
E + C GG PG +L+ +
Sbjct: 76 SPDTYDSSSSSSTTSVSDMLQLDDRDKVIVSERNSMCSTVNYPTWWDSCGGFPGFLLSLN 135
Query: 78 D------QGKKDISIFYGSNILDYVVSTWRYFVFRFGLDLKVSTLKNSEC--YQDSTITV 129
D G+ + +G + + +S+ R+F + ++L V ++E + D I V
Sbjct: 136 DISEPGETGEASPFVLHGPSEVHQFLSSMRHFTYHTNVNLTVQGYTSAEAPVFVDENICV 195
Query: 130 KSIVISNSANVDQCVQQHQSLGF-TNG--LKNIIARMFPEVNPTDEQDPS---ANSTLNV 183
+V+S N + ++H+++ TN LK A P D S N+ N
Sbjct: 196 TPVVVSLVKNSFK-KRKHENINRGTNARPLKEDRANTSPHWYSHVSNDTSFVVENAMYNT 254
Query: 184 DIPPEAIGAKNLTTSYELTFPAVRGKFNVEEAKRLGVPKGRLYAELAKGNSITLEDGTVI 243
P E L SY + GKF+ +AK LG+ KG LA+G +TLE+G +
Sbjct: 255 PAPLEP-DKPELFISYIVQSHPTPGKFDAAKAKSLGITKGLDCGRLARGEPVTLENGKTV 313
Query: 244 NSDQVLSETRNFGKVLVLDIPSNKYIPRFIDEFKNYPTDQLSAIYYFLGDEVTITDDLFQ 303
+V+ + ++ P+ I I+ K + + + + EV + +Q
Sbjct: 314 YPKEVIGPSIPGSSFFIIHCPNELVIDLVIENHKWTNAPKPVCVIHSVTPEV-YKNPRYQ 372
Query: 304 FFDTFSDDQIQHYVSHSSISPNTIAYESAAIATLKLKALQVESYNIPITDRVYSREFFHC 363
+ + ++ H ++ + ++ I Y +A+A L L + + + F+C
Sbjct: 373 SWISSFPSEVSHLIASTEVN-EVINYPRSAVAIATLNLLDSKVFPLG----------FNC 421
Query: 364 FPKDLPEGSSLVQQQEHVPSCLVKNENMHVFEKMKGIALEPFTVGKENMVIHESQLPTAK 423
+ + Q++ K + F K GI + VG + I E + K
Sbjct: 422 Y--------EVKNVQKNNRIAFAKPKLRFAFGKKTGI--DDSEVG---VSIEELKDKILK 468
Query: 424 QSSTIDELYESHVVPLCIEGSSLERTVHEQVHVNNFDNKTKLNEIEIISLGTGSALPSKY 483
+ Y+S V ++ V ++ +F ++I+I +LGTGSA+PS Y
Sbjct: 469 EKPD----YKSFV-------EEAQKYVSDKPKAPSFAG----SDIQICTLGTGSAMPSLY 513
Query: 484 RNVISTLVKIPYTEV---DGTVVNRSILLDAGENTLGTIHRTIPDIDVPKLFRDVKLIYL 540
RNV ST V+IP + D + ++ILLD GE TLG + R D ++ ++ IY+
Sbjct: 514 RNVSSTYVRIPVDKKCMEDSAISMKNILLDCGEGTLGRLSRQYGD-NLKYEIASLRWIYI 572
Query: 541 SHLHADHHLGIASLIKEWYKHNKHTADKLYVITPWQYNIFVREWFSLEDPAILSRIEYIS 600
SH+HADHH G+ ++K W K++ + KL++ P Q+ ++ E+ SRI+Y+
Sbjct: 573 SHMHADHHAGVIGVLKAWTKYSDGRS-KLFITAPPQFEFWLLEY---------SRIDYL- 621
Query: 601 CEHLKAGDDIRKQTKPLSMDVDGTYATKGRKDLEHDEESAVKDTAKIKKLMQNLRLMSFR 660
PLS V + + L D + + +++++ L + L+SFR
Sbjct: 622 ---------------PLSNIVFISNSA-----LRTDRKPSALESSRLSSLFKEFDLVSFR 661
Query: 661 TCPAIHCDWAYCNSISFFLSARSKELFKLSYSGDTRPNFNQFARGIGKNSDLLIHEATLE 720
T PAIHC ++YC I+ + +K++YSGDTRP+ FA I K+S LLIHEATLE
Sbjct: 662 TVPAIHCPYSYCMEIT------NSSGWKIAYSGDTRPS-EDFAN-IAKDSTLLIHEATLE 713
Query: 721 NELKVEAMKKRHSTINEAIKVSNTMNARKLLLTHFSQRYPKVPNTNRSIKLNARELCFAF 780
+ + A+KK+HST +EA++V+ + ++LTHFSQRYPK+P+ + I + AF
Sbjct: 714 DSMHEIAIKKQHSTYSEALEVAKKAGTKNVILTHFSQRYPKLPDID--ISTEDLHIALAF 771
Query: 781 DGMIVSFNELGKQQDKIDLLGSIFVEEENDAKKEDVK 817
DGM + +++ + L +F EE + + +K
Sbjct: 772 DGMTLKISDISLFRYFGKPLAYLFNEENLKEESDPLK 808
>7303764 [R] KOG2121 Predicted metal-dependent hydrolase (beta-lactamase
superfamily)
Length = 743
Score = 212 bits (540), Expect = 2e-54
Identities = 213/800 (26%), Positives = 337/800 (41%), Gaps = 140/800 (17%)
Query: 28 KYFFGKIGEGSQRACNESKVKFGKLNGIFLTGEMDYSCIGGLPGLILTASDQGKKDISIF 87
+Y F GEG+QR +E K + +L IFLT SC GGLPGL LT D G +DI +
Sbjct: 60 RYLFN-CGEGTQRLAHEHKTRLSRLEQIFLTQNTWASC-GGLPGLTLTIQDAGVRDIGL- 116
Query: 88 YGSNILDYVVSTWRYFVFRFGLDLKVSTLKNSECYQDSTITVKSIVISNSANVDQCVQQH 147
+G L ++ + R FV L ++ + C++DS + V S+ + NS +
Sbjct: 117 HGPPHLGSMLQSMRRFVVLKNLQVRPNDCSEGACFEDSILKVDSLPLINSEDP------- 169
Query: 148 QSLGFTNGLKNIIARMFPEVNPTDEQDPSANSTLNVDIPPEAIGAKNLTTSYELTFPAVR 207
T + N I ++ P
Sbjct: 170 -----TKSVINYICQLKPRA---------------------------------------- 184
Query: 208 GKFNVEEAKRLGVPKGRLYAELAKGNSITLEDGTVINSDQVLSETRNFGKVLVLDIPSNK 267
G N+ + GVP G L +L GN ITL DG V+ S V + + LD+PS
Sbjct: 185 GALNLVKCVEQGVPPGPLLGQLKNGNDITLPDGKVVRSVDVTEASETALSFVFLDVPSEN 244
Query: 268 YIPRFIDEFKNYPT------DQLSAIYYFLGDEVTITDDLFQFF-DTFSDDQIQHYVSHS 320
Y+P + K +++ + +F ++ F ++FS + Y+S
Sbjct: 245 YLPALLTHGKRLKKLGEEKLTEVALVVHFTPYHISSRQVYKDFVVESFSSEAQHIYLS-- 302
Query: 321 SISPNTIAYESAAIATLKLKALQVESYNIPITDRVYSREFFHCFPKDLPEGSSLVQQQEH 380
SP AA ++ + Q+ P+ S C + L + E
Sbjct: 303 --SPLNQFSGYAAAHRIQHQLHQLAPQVFPLLGEQLS-----CQSQTLSLNLKKTKLDE- 354
Query: 381 VPSCLVKNENMHVFEKMKGIALEPFTVGKENMVIHESQLPTAKQSSTIDELY--ESHVVP 438
S N + E+ +A+ + + L +S E Y E+H VP
Sbjct: 355 ADSEDKANAKANETEEQGVVAMTNYHLRPRK------GLDRTLESKLTPEEYVKETHAVP 408
Query: 439 LCIEGSSLERTVHEQVHVNNFDNKTKLNEIEIISLGTGSALPSKYRNVISTLVKIPYTEV 498
+E L E+ +F + + + +II LGTGS +P+K RNV S L++
Sbjct: 409 GFLE---LLAKFKEEY---SFPDNSADSYPKIIFLGTGSCIPNKTRNVSSILIR------ 456
Query: 499 DGTVVNRSILLDAGENTLGTIHRTIPDIDVPKLFRDVKLIYLSHLHADHHLGIASLIKEW 558
T ++ +LLD GE T G I R + R ++ IY+SHLHADHH+G+ L++E
Sbjct: 457 --TAIDAYVLLDCGEGTYGQIVRLYGHEKGQLILRQLQAIYVSHLHADHHIGLIGLLRE- 513
Query: 559 YKHNKHTADKLYVITPWQYNIFVREWFSLEDPAILSRIEYISCEHLKAGDDIRKQTKPLS 618
+ K AD L ++ P Q + W + I +
Sbjct: 514 RRQLKPRADPLILLAPRQ----IEPWLEFYNRQIET------------------------ 545
Query: 619 MDVDGTYATKGRKDLEHDEESAVKDTAKIKKLMQNLRLMSFRTCPAIHCDWAYCNSISFF 678
V+ Y G +L S + ++ L + S TC HC ++ IS
Sbjct: 546 --VEDAYTLVGNGELLASPLSGEQ--------VERLGITSISTCLVRHCPNSF--GISLT 593
Query: 679 LSAR-SKELFKLSYSGDTRPNFNQFARGIGKNSDLLIHEATLENELKVEAMKKRHSTINE 737
L+A+ + E K++YSGDT P Q +G++S +LIHEAT+E++L+ EA K HST+++
Sbjct: 594 LAAKHNSEPVKITYSGDTMPC--QDLIDLGRDSTVLIHEATMEDDLEEEARLKTHSTVSQ 651
Query: 738 AIKVSNTMNARKLLLTHFSQRYPKVPNTNRSIKLNARELCFAFDGMIVSFNELGKQQDKI 797
AI+ MNAR +L+HFSQRY K P + + + AFD M V+ +L
Sbjct: 652 AIQQGRNMNARHTILSHFSQRYAKCPRLPSDEDM--QRVAIAFDNMEVTVEDLQHYHKLY 709
Query: 798 DLLGSIFVEEENDAKKEDVK 817
L +++ E + ++ VK
Sbjct: 710 PALFAMYAEYTEELEQRAVK 729
>At3g16260 [R] KOG2121 Predicted metal-dependent hydrolase (beta-lactamase
superfamily)
Length = 937
Score = 199 bits (506), Expect = 1e-50
Identities = 221/856 (25%), Positives = 377/856 (43%), Gaps = 118/856 (13%)
Query: 12 LDTKQ--PLLLLQSDHGDKYFFGKIGEGSQRACNESKVKFGKLNGIFLTGEMDYSCIGGL 69
+DT+ P +LL D + F GEG QR C E K+K K++ IFL+ + GGL
Sbjct: 133 MDTQDTSPSVLLFFDK--QRFIFNAGEGLQRFCTEHKIKLSKVDHIFLSRVCSETA-GGL 189
Query: 70 PGLILTASDQGKKDISI-FYGSNILDYVVSTWRYFVFRFGLDLKVSTLKNSECYQDSTIT 128
PGL+LT + G++ +S+ +G + L Y+V R F+ R +
Sbjct: 190 PGLLLTLAGIGEQGLSVNVWGPSDLKYLVDAMRSFIPRAAM------------------- 230
Query: 129 VKSIVISNSANVDQCVQQHQSLGFTNGLKNIIARMFPEVNPTDEQDPSANSTLNVDIPPE 188
V + S N+ Q +G + + + D++ ++ L E
Sbjct: 231 VHTRSFGPSLNISDSAPQ---IGLSKPKDDAYVLV-------DDEVVKISAILLEPSRLE 280
Query: 189 AIGAKNLTTS--YELTFPAVRGKFNVEEAKRLGVPKGRLYAELAKGNSIT--LEDGTVIN 244
G+K T+ Y P ++GKF+ ++A LG+ G Y+ L G S+ +D TV
Sbjct: 281 ESGSKPGETAVIYVCELPEIKGKFDPKKAMALGLRAGPKYSYLQSGQSVKSDFKDITVHP 340
Query: 245 SDQVLSETRNFGKVLVLDIPSNKYIPRFIDEFKNYPTDQLSAIYYFLGDEVTITDDLFQF 304
SD V+ + VL++D P+ + +E + P+ + YY D T L
Sbjct: 341 SD-VMGPSVPGPVVLLVDCPTESHA----EELLSIPSMKT---YYSCLDNSTDGAKLVNC 392
Query: 305 FDTFSDDQIQHYVSHSSISPNTIAYESAAIATLKLKALQVESYNIPITDRVYSREFFHCF 364
S + + ++ S + SA +A +E + + R+ +R + C
Sbjct: 393 IIHLSPASVTNSSTYRSWMKR---FHSAQHILAGHEAKNMEFPILRASSRITARLNYLC- 448
Query: 365 PKDLPEGSSLVQQQEHV---PSCLVKNENMHVFEKMKGIALEPFTVGKE-NMVIHESQLP 420
P+ P Q ++ P+ L K + ++ E + L FT+ N+ + S +P
Sbjct: 449 PQFFPAPGFWSHQHDNNSINPTSLSKCFDSNLGESISAENLLKFTLRPHGNLGVDRSSIP 508
Query: 421 TAKQSSTIDELYESHVVPLCIEGSSLERTVHEQVH-------------VNNFDNKTKLNE 467
+ + + + S + + + +++ + Q + V + + ++
Sbjct: 509 SRLTALRVMDELLSEIPEISSKTEEIKQLWNGQHNKMMIEEPWLGESTVPSCLENIRRDD 568
Query: 468 IEIISLGTGSALPSKYRNVISTLVKIPYTEVDGTVVNRSILLDAGENTLGTIHRTIPDID 527
+EI+ LGTGS+ PSKYRNV + + + SILLD GE TLG + R
Sbjct: 569 MEIVLLGTGSSQPSKYRNVTAIYIDL--------FSRGSILLDCGEGTLGQLKRRYGLEG 620
Query: 528 VPKLFRDVKLIYLSHLHADHHLGIASLI---KEWYKHNKHTADKLYVITPWQYNIFVREW 584
+ R+++ I++SH+HADHH G+A ++ +E K H + V+ P F+ +
Sbjct: 621 ADEAVRNLRCIWISHIHADHHTGLARILARRRELLKGLAH--EPAIVVGPRSLKNFLDAY 678
Query: 585 FSLEDPAILSRIEYISCEHLKAG-----DDIRKQTKPLSMDVDGTYATKGR--------- 630
LED +E++ C + + R + S + +G+ +KG
Sbjct: 679 QRLED----LDMEFLDCRNTTTTSWASVETSRPEKNTSSGNAEGSLFSKGSLMQSIYKRP 734
Query: 631 KDLEHDEESAVKDTAKIKKLMQNLRLMSFRTCPAIHCDWAYCNSISFFLSARSKEL---- 686
D SA+ K+KK++ + L + P +HC A+ S+ +A K +
Sbjct: 735 SSPLTDNSSALPFLKKLKKVLGEMGLEHLISFPVVHCPQAFGVSLK---AAERKNIAGDE 791
Query: 687 ---FKLSYSGDTRPNFNQFARGIGKNSDLLIHEATLENELKVEAMKKRHSTINEAIKVSN 743
+K+ YSGDTRP K + +LIHEAT E+ L EA+ K HST EAIKV +
Sbjct: 792 IPGWKMVYSGDTRPCPEMVEAS--KGATVLIHEATFEDALVEEAVAKNHSTTKEAIKVGS 849
Query: 744 TMNARKLLLTHFSQRYPKVPNTNRSIKLNARELCFAFDGMIVSFNELGKQQDKIDLLGSI 803
+ + +LTHFSQRYPK+P + S + C AFD M ++ +L + ++
Sbjct: 850 SAGVYRTVLTHFSQRYPKIPVIDES---HMHNTCIAFDMMSINMADLHVLPKILPYFKTL 906
Query: 804 F----VEEENDAKKED 815
F VEEE + ++ D
Sbjct: 907 FRNQVVEEEEEEEETD 922
>At1g52160 [R] KOG2121 Predicted metal-dependent hydrolase (beta-lactamase
superfamily)
Length = 837
Score = 196 bits (499), Expect = 9e-50
Identities = 214/847 (25%), Positives = 368/847 (43%), Gaps = 119/847 (14%)
Query: 13 DTKQPLLLLQSDHGDKYFFGKIGEGSQRACNESKVKFGKLNGIFLTGEMDYSCIGGLPGL 72
DT +LL + F GEG QR C E K+K K++ +FL+ + GGLPGL
Sbjct: 64 DTSSSVLLF---FDKQRFIFNAGEGLQRFCTEHKIKLSKIDHVFLSRVCSETA-GGLPGL 119
Query: 73 ILTASDQGKKDISI-FYGSNILDYVVSTWRYFVFRFGLDLKVSTLKNSECYQDSTITVKS 131
+LT + G++ +S+ +G + L+Y+V + F+ R + S +S D + V
Sbjct: 120 LLTLAGIGEEGLSVNVWGPSDLNYLVDAMKSFIPRAAMVHTRSFGPSST--PDPIVLVND 177
Query: 132 IVISNSANVDQCVQQHQSLGFTNGLKNIIARMFPEVNPTDEQDPSANSTLNVDIPPEAIG 191
V+ SA + + P ++ S N +
Sbjct: 178 EVVKISAII--------------------------LKPCHSEEDSGNKS----------- 200
Query: 192 AKNLTTSYELTFPAVRGKFNVEEAKRL-GVPKGRLYAELAKGNSITLEDGTV-INSDQVL 249
+L+ Y P + GKF++E+AK++ GV G Y+ L G S+ ++ + ++ V+
Sbjct: 201 -GDLSVVYVCELPEILGKFDLEKAKKVFGVKPGPKYSRLQSGESVKSDERDITVHPSDVM 259
Query: 250 SETRNFGKVLVLDIPSNKYIPRF-----IDEFKNYPTDQ------LSAIYYFLGDEVTIT 298
+ VL++D P+ + ++ + + P +Q ++ I + VT +
Sbjct: 260 GPSLPGPIVLLVDCPTESHAAELFSLKSLESYYSSPDEQTIGAKFVNCIIHLSPSSVTSS 319
Query: 299 DDLFQFFDTFSDDQIQHYVS-HSSISPNTI--AYESAAIATLKLKALQVESYNIPITDRV 355
+ F QH ++ H P I +++ + L+ S I
Sbjct: 320 PTYQSWMKKFH--LTQHILAGHQRFLPLLIIVSHQKTVRKNMAFPILKASS-RIAARLNY 376
Query: 356 YSREFFHC---FPKDLPEGSSLVQQQEHVPSCLVKNENMHVFEKMKGIALEPFTVGKENM 412
+FF +P L + S + + PS + + + P T +
Sbjct: 377 LCPQFFPAPGFWPSQLTDNSII----DPTPSNKFNLRPVAIRGIDRSCIPAPLTSSE--- 429
Query: 413 VIHE--SQLPTAK-QSSTIDELYESHVVPLCIEGSSLERTVHEQVHVNNFDNKTKLNEIE 469
V+ E S++P K +S I + + IE L + N K + +++E
Sbjct: 430 VVDELLSEIPEIKDKSEEIKQFWNKQHNKTIIEKLWLSEC---NTVLPNCLEKIRRDDME 486
Query: 470 IISLGTGSALPSKYRNVISTLVKIPYTEVDGTVVNRSILLDAGENTLGTIHRTIPDIDVP 529
I+ LGTGS+ PSKYRNV + + + S+LLD GE TLG + R
Sbjct: 487 IVILGTGSSQPSKYRNVSAIFIDL--------FSRGSLLLDCGEGTLGQLKRRYGLDGAD 538
Query: 530 KLFRDVKLIYLSHLHADHHLGIASLIKEWYKHNKH-TADKLYVITPWQYNIFVREWFSLE 588
+ R ++ I++SH+HADHH G+A ++ K K T + + V+ P F+ + LE
Sbjct: 539 EAVRKLRCIWISHIHADHHTGLARILALRSKLLKGVTHEPVIVVGPRPLKRFLDAYQRLE 598
Query: 589 DPAILSRIEYISCEHLKAGDDIRKQTKPLSMDVDGTYATKG--------RKDLEHDEESA 640
D +E++ C A ++ + +G+ T+G R D+ D S
Sbjct: 599 D----LDMEFLDCRSTTATSWASLES---GGEAEGSLFTQGSPMQSVFKRSDISMDNSSV 651
Query: 641 VKDTAKIKKLMQNLRLMSFRTCPAIHCDWAYCNSISFFLSARS--KEL--FKLSYSGDTR 696
+ +KK++ + L + P +HC AY I S +++ +K+ YSGD+R
Sbjct: 652 LLCLKNLKKVLSEIGLNDLISFPVVHCPQAYGVVIKAAERVNSVGEQILGWKMVYSGDSR 711
Query: 697 PNFNQFARGIGKNSDLLIHEATLENELKVEAMKKRHSTINEAIKVSNTMNARKLLLTHFS 756
P +++ +LIHEAT E+ L EA+ K HST EAI V + N +++LTHFS
Sbjct: 712 PCPETVEAS--RDATILIHEATFEDALIEEALAKNHSTTKEAIDVGSAANVYRIVLTHFS 769
Query: 757 QRYPKVPNTNRSIKLNARELCFAFDGMIVSFNELGKQQDKIDLLGSIF----VEEE--ND 810
QRYPK+P + S + C AFD M ++ +L + ++F VE+E +D
Sbjct: 770 QRYPKIPVIDES---HMHNTCIAFDLMSINMADLHVLPKVLPYFKTLFRDEMVEDEDADD 826
Query: 811 AKKEDVK 817
+D+K
Sbjct: 827 VAMDDLK 833
>HsM11875213 [R] KOG2121 Predicted metal-dependent hydrolase (beta-lactamase
superfamily)
Length = 826
Score = 185 bits (469), Expect = 3e-46
Identities = 217/805 (26%), Positives = 352/805 (42%), Gaps = 119/805 (14%)
Query: 27 DKYFFGKIGEGSQRACNESKVKFGKLNGIFLTGEMDYSCIGGLPGLILTASDQGKKDISI 86
++Y F GEG QR E K+K +L+ IFLT M +S +GGL G+ILT + G +
Sbjct: 81 NRYLFN-CGEGVQRLMQEHKLKVARLDNIFLT-RMHWSNVGGLSGMILTLKETGLPKCVL 138
Query: 87 FYGSNILDYVVSTWRYFVFRFGLDLKVSTLKNSECYQDSTITVKSIVISNSANVDQCVQQ 146
+ Y+ + + G++L V E Y+D T+TV I I + +Q +
Sbjct: 139 SGPPQLEKYLEAIKIFSGPLKGIELAVRPHSAPE-YEDETMTVYQIPIHS----EQRRGK 193
Query: 147 HQSLGFTNGLKNIIARMFPEVNPTDEQDPSANSTLNVDIPPEAIGAKNLTTSYELTFPAV 206
HQ + ++R+ PE + E + + + + +L ++
Sbjct: 194 HQPW---QSPERPLSRLSPERSSDSESNENEPHLPHGVSQRRGVRDSSLVVAFICKLHLK 250
Query: 207 RGKFNVEEAKRLGVPKGR-----LYAELAKGNSITLEDGTVINSDQVLSETRNFGKVLVL 261
RG F V +AK +G+P G + A + G SIT E G I ++++ + +V+
Sbjct: 251 RGNFLVLKAKEMGLPVGTAAIAPIIAAVKDGKSITHE-GREILAEELCTPPDPGAAFVVV 309
Query: 262 DIPSNKYIPRFIDE--FKNYP--TDQLSAIYYFLGDEVTITDDLFQ-FFDTFSDDQIQHY 316
+ P +I + F+ Y D A+ + + D +Q + + F D QH
Sbjct: 310 ECPDESFIQPICENATFQRYQGKADAPVALVVHMAPASVLVDSRYQQWMERFGPDT-QHL 368
Query: 317 VSHSSISPNTIAYESAAIATLKLKALQVESYNIPITDRVYSREFFHCFPKDLPEGSSLVQ 376
V + + A++ L+ +Q + N+ D F C K+ P S +
Sbjct: 369 VLNENC---------ASVHNLRSHKIQTQ-LNLIHPDIFPLLTSFRC-KKEGPTLSVPMV 417
Query: 377 QQEHVPSCLVKNENMHVFEKMKGIALEPFTVGKENMVIHESQLPTAKQSSTIDELYESHV 436
Q E CL+K + E + + T E ++ QLP +QS + E S
Sbjct: 418 QGE----CLLKYQLRPRREWQRDAII---TCNPEEFIVEALQLPNFQQS--VQEYRRS-- 466
Query: 437 VPLCIEGSSLERTVHEQVHVNNFDNKTKLNEIEIISLGTGSALPSKYRNVISTLVKIPYT 496
+G + + + EII LGTGSA+P K RNV +TLV I
Sbjct: 467 ---AQDGPA--------------PAEKRSQYPEIIFLGTGSAIPMKIRNVSATLVNIS-- 507
Query: 497 EVDGTVVNRSILLDAGENTLGTIHRTIPDIDVPKLFRDVKLIYLSHLHADHHLGIASLIK 556
+ S+LLD GE T G + R D V ++ + +++SHLHADHH G+ S++
Sbjct: 508 ------PDTSLLLDCGEGTFGQLCRHYGD-QVDRVLGTLAAVFVSHLHADHHTGLPSILL 560
Query: 557 EWYKHNKHTADKLY---VITPWQYNIFVREWFSLEDPAILSRIEYISCEHLKAGDDIRKQ 613
+ + L+ V+ P Q +++++ + + +L I I + L+ G +I
Sbjct: 561 QRERALASLGKPLHPLLVVAPNQLKAWLQQYHN-QCQEVLHHISMIPAKCLQEGAEI--- 616
Query: 614 TKPLSMDVDGTYATKGRKDLEHDEESAVKDTAKIKKLMQNLRLMSFRTCPAIHCDWAYCN 673
S+ I L++ L F+TC HC A+
Sbjct: 617 -------------------------SSPAVERLISSLLRTCDLEEFQTCLVRHCKHAFGC 651
Query: 674 SISFFLSARSKELFKLSYSGDTRPNFNQFARGIGKNSDLLIHEATLENELKVEAMKKRHS 733
++ +K+ YSGDT P + +GK++ LLIHEATLE+ L+ EA++K HS
Sbjct: 652 ALVHTSG------WKVVYSGDTMPC--EALVRMGKDATLLIHEATLEDGLEEEAVEKTHS 703
Query: 734 TINEAIKVSNTMNARKLLLTHFSQRYPKVP--NTNRSIKLNARELCFAFDGMIVSFNELG 791
T ++AI V MNA ++L HFSQRY KVP + N S K+ AFD M V F +
Sbjct: 704 TTSQAISVGMRMNAEFIMLNHFSQRYAKVPLFSPNFSEKVGV-----AFDHMKVCFGDFP 758
Query: 792 KQQDKIDLLGSIFVE--EENDAKKE 814
I L ++F EE + ++E
Sbjct: 759 TMPKLIPPLKALFAGDIEEMEERRE 783
>Hs21359941 [R] KOG2121 Predicted metal-dependent hydrolase (beta-lactamase
superfamily)
Length = 826
Score = 184 bits (468), Expect = 4e-46
Identities = 222/813 (27%), Positives = 357/813 (43%), Gaps = 135/813 (16%)
Query: 27 DKYFFGKIGEGSQRACNESKVKFGKLNGIFLTGEMDYSCIGGLPGLILTASDQGKKDISI 86
++Y F GEG QR E K+K +L+ IFLT M +S +GGL G+ILT + G +
Sbjct: 81 NRYLFN-CGEGVQRLMQEHKLKVARLDNIFLT-RMHWSNVGGLSGMILTLKETGLPKCVL 138
Query: 87 FYGSNILDYVVSTWRYFVFRFGLDLKVSTLKNSECYQDSTITVKSIVISNSANVDQCVQQ 146
+ Y+ + + G++L V E Y+D T+TV I I + +Q +
Sbjct: 139 SGPPQLEKYLEAIKIFSGPLKGIELAVRPHSAPE-YEDETMTVYQIPIHS----EQRRGK 193
Query: 147 HQSLGFTNGLKNIIARMFPEVNPTDEQDPSANSTLNVDIP--PEAIGAK------NLTTS 198
HQ + ++R+ PE S++S LN + P P + + +L +
Sbjct: 194 HQPW---QSPERPLSRLSPE--------RSSDSELNENEPHLPHGVSQRRGVRDSSLVVA 242
Query: 199 YELTFPAVRGKFNVEEAKRLGVPKGR-----LYAELAKGNSITLEDGTVINSDQVLSETR 253
+ RG F V +AK +G+P G + A + G SIT E G I ++++ +
Sbjct: 243 FICKLHLKRGNFLVLKAKEMGLPVGTAAIAPIIAAVKDGKSITHE-GREILAEELCTPPD 301
Query: 254 NFGKVLVLDIPSNKYIPRFIDE--FKNYP--TDQLSAIYYFLGDEVTITDDLFQ-FFDTF 308
+V++ P +I + F+ Y D A+ + + D +Q + + F
Sbjct: 302 PGAAFVVVECPDESFIQPICENATFQRYQGKADAPVALVVHMAPASVLVDSRYQQWMERF 361
Query: 309 SDDQIQHYVSHSSISPNTIAYESAAIATLKLKALQVESYNIPITDRVYSREFFHCFPKDL 368
D QH V + + A++ L+ +Q + N+ D F C K+
Sbjct: 362 GPDT-QHLVLNENC---------ASVHNLRSHKIQTQ-LNLIHPDIFPLLTSFRC-KKEG 409
Query: 369 PEGSSLVQQQEHVPSCLVKNENMHVFEKMKGIALEPFTVGKENMVIHESQLPTAKQSSTI 428
P S + Q E CL+K + E + + T E ++ QLP +QS +
Sbjct: 410 PTLSVPMVQGE----CLLKYQLRPRREWQRDAII---TCNPEEFIVEALQLPNFQQS--V 460
Query: 429 DELYESHVVPLCIEGSSLERTVHEQVHVNNFDNKTKLNEIEIISLGTGSALPSKYRNVIS 488
E S +G + + + EII LGTGSA+P K RNV +
Sbjct: 461 QEYRRS-----AQDGPA--------------PAEKRSQYPEIIFLGTGSAIPMKIRNVSA 501
Query: 489 TLVKIPYTEVDGTVVNRSILLDAGENTLGTIHRTIPDIDVPKLFRDVKLIYLSHLHADHH 548
TLV I + S+LLD GE T G + R D V ++ + +++SHLHADHH
Sbjct: 502 TLVNIS--------PDTSLLLDCGEGTFGQLCRHYGD-QVDRVLGTLAAVFVSHLHADHH 552
Query: 549 LGIASLIKEWYKHNKHTADKLY---VITPWQYNIFVREWFSLEDPAILSRIEYISCEHLK 605
G+ S++ + + L+ V+ P Q +++++ + + +L I I + L+
Sbjct: 553 TGLPSILLQRERALASLGKPLHPLLVVAPNQLKAWLQQYHN-QCQEVLHHISMIPAKCLQ 611
Query: 606 AGDDIRKQTKPLSMDVDGTYATKGRKDLEHDEESAVKDTAKIKKLMQNLRLMSFRTCPAI 665
G +I S+ I L++ L F+TC
Sbjct: 612 EGAEI----------------------------SSPAVERLISSLLRTCDLEEFQTCLVR 643
Query: 666 HCDWAYCNSISFFLSARSKELFKLSYSGDTRPNFNQFARGIGKNSDLLIHEATLENELKV 725
HC A+ ++ +K+ YSGDT P + +GK++ LLIHEATLE+ L+
Sbjct: 644 HCKHAFGCALVHTSG------WKVVYSGDTMPC--EALVRMGKDATLLIHEATLEDGLEE 695
Query: 726 EAMKKRHSTINEAIKVSNTMNARKLLLTHFSQRYPKVP--NTNRSIKLNARELCFAFDGM 783
EA++K HST ++AI V MNA ++L HFSQRY KVP + N S K+ AFD M
Sbjct: 696 EAVEKTHSTTSQAISVGMRMNAEFIMLNHFSQRYAKVPLFSPNFSEKVGV-----AFDHM 750
Query: 784 IVSFNELGKQQDKIDLLGSIFVE--EENDAKKE 814
V F + I L ++F EE + ++E
Sbjct: 751 KVCFGDFPTMPKLIPPLKALFAGDIEEMEERRE 783
>SPBC3D6.03c [R] KOG2121 Predicted metal-dependent hydrolase (beta-lactamase
superfamily)
Length = 678
Score = 122 bits (306), Expect = 2e-27
Identities = 128/461 (27%), Positives = 203/461 (43%), Gaps = 87/461 (18%)
Query: 319 HSSISPNTIAYESAAIATLKLKALQVESYNIPITDRVYSREFFHCFPKDL--PEGSSLVQ 376
H + P + L AL S ++ VY H K + PE +
Sbjct: 245 HQVVGPPRKRQYFYVLGCSSLSALNQMSKHVDSFSDVYPTCIIHILEKGIWGPEYIKFLS 304
Query: 377 -----QQEHVPSCLVKNENMHVFEKMKGIALEP-------FTVGKENMVIHESQLPT--- 421
+ +H SC+ N VF++ KG + P F + K + + ++QLP
Sbjct: 305 HPKFSRAQHFISCIELASNNPVFQRNKGRNVLPACRDFAAFDI-KPSTLDTQTQLPENTY 363
Query: 422 AKQSSTIDELYESHVVPLCIEGSSLERTVHEQVHVNNFDNKTKLNEIEIIS-LGTGSALP 480
+ T LY+ I S V ++F+ NE + LGT + P
Sbjct: 364 VLKEETSMVLYDEQCK---ISESPSYSPVKLAKKFSSFNPLPFENEGYTLDVLGTSATCP 420
Query: 481 SKYRNVISTLVKIPYTEVDGTVVNRSILLDAGENTLGTIHRTIPDIDVPKLFRDVKLIYL 540
+ R++ S V I DGTV I+LD GE + R P L R +K I++
Sbjct: 421 TWRRSLSSYSVAI-----DGTV----IMLDCGEGAISQFFRQYGTNTEPML-RKLKAIFI 470
Query: 541 SHLHADHHLGIASLIKEWYKHNKHTADKLYVITP---WQYNIFVREWFSLEDPAILSRIE 597
+HLH+DH+LG+ ++++ W K N + + + +I P WQ+ ++ +L+ A+L+RI
Sbjct: 471 THLHSDHYLGLLNVLQAWNKANTNNSMHINIIGPKFLWQWLQRLKSPANLQ--ALLNRII 528
Query: 598 YISCEHLKAGDDIRKQTKPLSMDVDGTYATKGRKDLEHDEESAVKDTAKIKKLMQNLRLM 657
+I + T PL + D +
Sbjct: 529 FIIAKETV--------TTPLQLTSD----------------------------------L 546
Query: 658 SFRTCPAIHCDWAYCNSISFFLSARSKELFKLSYSGDTRPNFNQFARGIGKNSDLLIHEA 717
S + P+IH + +Y IS + KL YSGDTRPN GIG + LL+HE+
Sbjct: 547 SISSVPSIHINDSYSCIISH------TKYGKLVYSGDTRPNEKLVKAGIG--ASLLLHES 598
Query: 718 TLENELKVEAMKKRHSTINEAIKVSNTMNARKLLLTHFSQR 758
T E++LK EA++++HST +EA+ V+ +M A+ L+LTHFSQR
Sbjct: 599 TFEDDLKHEAIQRQHSTASEALSVAQSMKAKALILTHFSQR 639
>CE29248 [R] KOG2121 Predicted metal-dependent hydrolase (beta-lactamase
superfamily)
Length = 850
Score = 117 bits (293), Expect = 7e-26
Identities = 163/692 (23%), Positives = 269/692 (38%), Gaps = 113/692 (16%)
Query: 155 GLKNIIARMFPEVNPTDEQDPSANSTLNVDIPPEAIGAKNLTTSYELTFPAVRGKFNVEE 214
GLK + P +N + S N +N N+ ++ + + + +
Sbjct: 222 GLKVTYIPLSPPLNIGSNNEKSKNVKVN-----------NVDIAFLIEMKEAARRIDTMK 270
Query: 215 AKRLGVPKGRLYAELAKGNSITLEDGTVINSDQVLSETRNFGK---VLVLDIPSNKYIPR 271
L VPKG L +L G ++TL DG I DQV S + G +LV + + ++
Sbjct: 271 LMELKVPKGPLIGKLKSGEAVTLPDGRTIQPDQVFSSDKVEGDKPLLLVTECTTEDHVKA 330
Query: 272 FIDEFKNYP----TDQLSAIYYFLGDEVTITDDLFQFFDTFSDDQIQHYVSHSSISPNTI 327
ID P QL + + D V T + ++ I H + + +P
Sbjct: 331 LIDSSSLQPFLNGEKQLDYMVHISDDAVINTPTYRHLMEKLNNPSITHLLINGG-NPVIP 389
Query: 328 AYESAAIATLKLKALQVESYNIPITDRVYSREFFHCFPKDLP-EGSSLVQQQEHVPSC-- 384
A ES T L+++ FP P + S ++ Q E +
Sbjct: 390 AVESVYKHTRLLRSIAPS-----------------LFPALHPIDWSGIITQNEELSQRQD 432
Query: 385 -LVKNENMHVFEKMKGIAL--EPFTVGKENMVIHESQLPTAKQSSTIDELYESHVVPLCI 441
++ M + +G + EP N++ E +L S EL + +
Sbjct: 433 QFIRVAPMQRYWMRRGASFNEEPIV---NNLLAAEPEL-----SDKAKELIKEY------ 478
Query: 442 EGSSLERTVHEQVHVNNFDNKTKLNEIEIISLGTGSALPSKYRNVISTLVKIPYTEVDGT 501
LE+ +NK ++ GT SA+PSKYRNV LV+
Sbjct: 479 --QKLEK-----------ENKMDCEFPKLTFFGTSSAVPSKYRNVTGYLVEASE------ 519
Query: 502 VVNRSILLDAGENTLGTIHRTIPDIDVPKLFRDVKLIYLSHLHADHHLGIASLIKEWYKH 561
N +IL+D GE T G + + +L ++ + ++H H DH G+ ++I
Sbjct: 520 --NSAILIDVGEGTYGQMRAVFGEDGCKQLLVNLNCVLITHAHQDHMNGLYTIIAR---- 573
Query: 562 NKHTADKLYVITPWQYNIFVREWFSLEDPAILSRIEYISCEHLKAGDDIRKQTKPLSMDV 621
K + L P++ + V L+ P I + + EHL DI +
Sbjct: 574 RKEAFESLGA--PYRPLVLVCNRNVLK-PMKTYSICFENIEHLLEIVDISRYPLTPPGSP 630
Query: 622 DGTYATKGRKDLEHDEESAVKDTAKIKKLMQNLRLMSFRTCPAIHCDWAYCNSISFFLSA 681
G + R H S +D + + + A+ + F +
Sbjct: 631 GGPPGKRPRLPSPHLPPS--RDVLQDMSSSFDKKAWKLDELKAVQVHHTRMAN-GFVMRV 687
Query: 682 RSKELFKLSYSGDTRPNFNQFARGIGKNSDLLIHEATLENELKVE--------------- 726
K ++ +SGDT+P GK++D+L+HE+T E+ +V+
Sbjct: 688 AGK---RIVFSGDTKPC--DLLVEEGKDADVLVHESTFEDGHEVDMTPKPPKKLAKISSL 742
Query: 727 --AMKKRHSTINEAIKVSNTMNARKLLLTHFSQRYPKVPNTNRSIKLNARELCFAFDGMI 784
AM+KRHST+ +A+ V MNA+ ++LTHFS RYPKVP L+ + A D +
Sbjct: 743 ADAMRKRHSTMGQAVDVGKRMNAKHIILTHFSARYPKVPVLPE--YLDKENIGVAMDMLR 800
Query: 785 VSFNELGKQQDKIDLLGSIFVEE--ENDAKKE 814
V F+ L + + +FV E E KKE
Sbjct: 801 VRFDHLPLVSKLLPIFREVFVAELFELTIKKE 832
>ECU06g0440 [R] KOG2121 Predicted metal-dependent hydrolase (beta-lactamase
superfamily)
Length = 744
Score = 112 bits (280), Expect = 2e-24
Identities = 95/292 (32%), Positives = 134/292 (45%), Gaps = 52/292 (17%)
Query: 470 IISLGTGSALPSKYRNVISTLVKIPYTEVDGTVVNRSILLDAGENTLGTIHRTIPDIDVP 529
I+ LGTG A+PSKYRNV S L + + +I+LD GE+ L IHR ++DV
Sbjct: 463 ILFLGTGCAIPSKYRNVSSILYESD---------SAAIMLDCGEDALFQIHRAYGELDVL 513
Query: 530 KLFRDVKLIYLSHLHADHHLGIASLIKEWYKHNKHTADKLYVITPWQYNIFVREWFSLED 589
K R I++SH HADH LGIAS++ K ++ + P FV + +
Sbjct: 514 KKLR---AIFISHSHADHVLGIASVL-------KRLDHRIKIFAPVAIRPFVEHFGAKSH 563
Query: 590 PAILSRIEYISCEHLKAGDDIRKQTKPLSMDVDGTYATKGRKDLEHDEESAVKDTAKIKK 649
EYI H K + + + D GT + E+ ++ A +
Sbjct: 564 -------EYIETNHAKGLERVFR-------DKIGTPTQDFPSHTINVEDYLLRSDAGFE- 608
Query: 650 LMQNLRLMSFRTCPAIHCDWAYCNSISFFLSARSKELFKLSYSGDTRPNFNQFARGIGKN 709
C HC S S + R L+YSGD+RP + + N
Sbjct: 609 ---------IAICGVDHC------SDSCGIRVRDGTTV-LAYSGDSRP--STLFGMMSSN 650
Query: 710 SDLLIHEATLENELKVEAMKKRHSTINEAIKVSNTMNARKLLLTHFSQRYPK 761
SD++IHEAT ++ + A HSTI+EA K+ +R LLLTHFSQRY K
Sbjct: 651 SDVMIHEATFASDQQERAAHTGHSTIDEAAKIFEMSQSRTLLLTHFSQRYSK 702
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.318 0.136 0.392
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 49,804,859
Number of Sequences: 60738
Number of extensions: 2233665
Number of successful extensions: 5495
Number of sequences better than 1.0e-05: 10
Number of HSP's better than 0.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 5421
Number of HSP's gapped (non-prelim): 31
length of query: 822
length of database: 30,389,216
effective HSP length: 115
effective length of query: 707
effective length of database: 23,404,346
effective search space: 16546872622
effective search space used: 16546872622
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)