ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI4489 check: MH G KOG0658 Carbohydrate transport and metabolism Glycogen synthase kinase-3
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI4489 1563106 1561862 -415
(415 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YMR139w [G] KOG0658 Glycogen synthase kinase-3 448 e-126
YDL079c [G] KOG0658 Glycogen synthase kinase-3 377 e-104
At4g00720 [G] KOG0658 Glycogen synthase kinase-3 361 e-99
At3g05840 [G] KOG0658 Glycogen synthase kinase-3 357 1e-98
At5g26751 [G] KOG0658 Glycogen synthase kinase-3 353 3e-97
At4g18710 [G] KOG0658 Glycogen synthase kinase-3 347 2e-95
At1g06390 [G] KOG0658 Glycogen synthase kinase-3 347 2e-95
At2g30980 [G] KOG0658 Glycogen synthase kinase-3 347 2e-95
At1g09840 [G] KOG0658 Glycogen synthase kinase-3 347 2e-95
At5g14640 [G] KOG0658 Glycogen synthase kinase-3 346 4e-95
At3g61160 [G] KOG0658 Glycogen synthase kinase-3 345 5e-95
At1g57870 [G] KOG0658 Glycogen synthase kinase-3 345 7e-95
Hs22051130 [G] KOG0658 Glycogen synthase kinase-3 343 3e-94
Hs11995474 [G] KOG0658 Glycogen synthase kinase-3 343 3e-94
CE21401 [G] KOG0658 Glycogen synthase kinase-3 343 3e-94
7290342 [G] KOG0658 Glycogen synthase kinase-3 342 6e-94
HsM4504163 [G] KOG0658 Glycogen synthase kinase-3 341 1e-93
Hs21361340 [G] KOG0658 Glycogen synthase kinase-3 333 2e-91
SPAC1687.15 [G] KOG0658 Glycogen synthase kinase-3 326 4e-89
SPBC8D2.01 [G] KOG0658 Glycogen synthase kinase-3 298 1e-80
SPBPI064 [G] KOG0658 Glycogen synthase kinase-3 261 1e-69
CE08727 [G] KOG0658 Glycogen synthase kinase-3 249 5e-66
YNL307c [G] KOG0658 Glycogen synthase kinase-3 218 2e-56
YOL128c [G] KOG0658 Glycogen synthase kinase-3 181 2e-45
ECU07g1270 [G] KOG0658 Glycogen synthase kinase-3 178 2e-44
7297578 [T] KOG0661 MAPK related serine/threonine protein kinase 174 2e-43
7298004 [G] KOG0658 Glycogen synthase kinase-3 173 5e-43
Hs4502743 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 169 5e-42
At1g76540 [R] KOG0594 Protein kinase PCTAIRE and related kinases 169 5e-42
At1g20930 [R] KOG0594 Protein kinase PCTAIRE and related kinases 166 5e-41
At1g73670 [T] KOG0660 Mitogen-activated protein kinase 165 1e-40
At1g18150 [T] KOG0660 Mitogen-activated protein kinase 164 2e-40
Hs4505569 [R] KOG0593 Predicted protein kinase KKIAMRE 164 3e-40
Hs4507281 [R] KOG0593 Predicted protein kinase KKIAMRE 163 4e-40
Hs4758652 [R] KOG0593 Predicted protein kinase KKIAMRE 162 7e-40
At4g19110 [T] KOG0661 MAPK related serine/threonine protein kinase 162 7e-40
At3g48750 [R] KOG0594 Protein kinase PCTAIRE and related kinases 162 7e-40
SPAC24B11.06c [T] KOG0660 Mitogen-activated protein kinase 161 2e-39
Hs7705551 [T] KOG0661 MAPK related serine/threonine protein kinase 160 3e-39
At2g42880 [T] KOG0660 Mitogen-activated protein kinase 160 4e-39
At2g38620 [R] KOG0594 Protein kinase PCTAIRE and related kinases 160 4e-39
7300773 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 160 4e-39
CE12408 [T] KOG0661 MAPK related serine/threonine protein kinase 159 6e-39
Hs11496279 [T] KOG0661 MAPK related serine/threonine protein kinase 159 7e-39
At3g18040 [T] KOG0660 Mitogen-activated protein kinase 159 9e-39
At3g14720 [T] KOG0660 Mitogen-activated protein kinase 159 9e-39
At5g19010 [T] KOG0660 Mitogen-activated protein kinase 158 1e-38
Hs7662388 [T] KOG0661 MAPK related serine/threonine protein kinase 158 2e-38
Hs4502709 [R] KOG0594 Protein kinase PCTAIRE and related kinases 158 2e-38
At3g59790 [T] KOG0660 Mitogen-activated protein kinase 157 2e-38
At5g45430 [T] KOG0661 MAPK related serine/threonine protein kinase 157 3e-38
At1g67580 [R] KOG0663 Protein kinase PITSLRE and related kinases 157 3e-38
At1g53510 [T] KOG0660 Mitogen-activated protein kinase 157 3e-38
At1g66750 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 156 6e-38
At2g18170 [T] KOG0660 Mitogen-activated protein kinase 155 8e-38
YLR113w [T] KOG0660 Mitogen-activated protein kinase 155 1e-37
CE29020 [T] KOG0660 Mitogen-activated protein kinase 155 1e-37
Hs4557439 [R] KOG0594 Protein kinase PCTAIRE and related kinases 154 2e-37
YDL108w [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 153 4e-37
At3g45640 [T] KOG0660 Mitogen-activated protein kinase 153 4e-37
At2g43790 [T] KOG0660 Mitogen-activated protein kinase 153 4e-37
At1g73690 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 153 4e-37
SPBC19F8.07 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polyme... 153 5e-37
7297009 [R] KOG0593 Predicted protein kinase KKIAMRE 153 5e-37
At2g01450 [T] KOG0660 Mitogen-activated protein kinase 152 7e-37
At1g18040 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 152 7e-37
CE05377 [G] KOG0658 Glycogen synthase kinase-3 152 9e-37
ECU08g1920 [R] KOG0594 Protein kinase PCTAIRE and related kinases 151 2e-36
Hs20986529 [T] KOG0660 Mitogen-activated protein kinase 151 2e-36
CE20405 [G] KOG0658 Glycogen synthase kinase-3 151 2e-36
Hs20986531 [T] KOG0660 Mitogen-activated protein kinase 150 3e-36
7290565 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 150 3e-36
Hs4826675 [UT] KOG0662 Cyclin-dependent kinase CDK5 149 1e-35
Hs20986501 [T] KOG0660 Mitogen-activated protein kinase 149 1e-35
Hs20986497 [T] KOG0660 Mitogen-activated protein kinase 149 1e-35
Hs20562757 [T] KOG0660 Mitogen-activated protein kinase 149 1e-35
Hs16936528 [R] KOG0594 Protein kinase PCTAIRE and related kinases 148 1e-35
CE06686 [T] KOG0660 Mitogen-activated protein kinase 148 1e-35
CE06762 [T] KOG0660 Mitogen-activated protein kinase 147 2e-35
At1g33770 [D] KOG0600 Cdc2-related protein kinase 147 2e-35
Hs17461944 [R] KOG0593 Predicted protein kinase KKIAMRE 145 8e-35
At3g54180 [R] KOG0594 Protein kinase PCTAIRE and related kinases 145 8e-35
At1g59580 [T] KOG0660 Mitogen-activated protein kinase 145 8e-35
At4g36450 [T] KOG0660 Mitogen-activated protein kinase 145 1e-34
7300650 [R] KOG0594 Protein kinase PCTAIRE and related kinases 145 1e-34
At4g13020 [T] KOG0661 MAPK related serine/threonine protein kinase 144 2e-34
7303804 [R] KOG0663 Protein kinase PITSLRE and related kinases 144 2e-34
CE00315 [R] KOG0594 Protein kinase PCTAIRE and related kinases 144 3e-34
At5g63370 [R] KOG0663 Protein kinase PITSLRE and related kinases 144 3e-34
At4g01370 [T] KOG0660 Mitogen-activated protein kinase 144 3e-34
At2g46070 [T] KOG0660 Mitogen-activated protein kinase 144 3e-34
At1g10210 [T] KOG0660 Mitogen-activated protein kinase 144 3e-34
Hs7657498 [T] KOG0661 MAPK related serine/threonine protein kinase 143 4e-34
Hs20128774 [T] KOG0660 Mitogen-activated protein kinase 143 4e-34
SPBC11B10.09 [R] KOG0594 Protein kinase PCTAIRE and related kinases 142 9e-34
7303051 [UT] KOG0662 Cyclin-dependent kinase CDK5 142 9e-34
Hs4502731 [R] KOG0663 Protein kinase PITSLRE and related kinases 142 1e-33
Hs16950647 [R] KOG0663 Protein kinase PITSLRE and related kinases 142 1e-33
YHR030c [T] KOG0660 Mitogen-activated protein kinase 141 2e-33
CE24971 [T] KOG0660 Mitogen-activated protein kinase 141 2e-33
CE01583 [T] KOG0660 Mitogen-activated protein kinase 141 2e-33
Hs4505649 [R] KOG0594 Protein kinase PCTAIRE and related kinases 141 2e-33
Hs7706059 [R] KOG0593 Predicted protein kinase KKIAMRE 140 3e-33
Hs4506085 [T] KOG0660 Mitogen-activated protein kinase 140 3e-33
CE29478 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 140 3e-33
CE29477 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 140 3e-33
CE29476 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 140 3e-33
At3g05050 [D] KOG0600 Cdc2-related protein kinase 140 5e-33
CE02602_1 [T] KOG0660 Mitogen-activated protein kinase 140 5e-33
CE26988 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 139 6e-33
At5g50860 [D] KOG0600 Cdc2-related protein kinase 139 6e-33
At1g07880 [T] KOG0660 Mitogen-activated protein kinase 139 6e-33
Hs16357494 [R] KOG0663 Protein kinase PITSLRE and related kinases 139 8e-33
Hs16357492 [R] KOG0663 Protein kinase PITSLRE and related kinases 139 8e-33
At1g53050 [D] KOG0600 Cdc2-related protein kinase 139 1e-32
Hs16357498 [R] KOG0663 Protein kinase PITSLRE and related kinases 138 1e-32
Hs16357486 [R] KOG0663 Protein kinase PITSLRE and related kinases 138 1e-32
Hs16357484 [R] KOG0663 Protein kinase PITSLRE and related kinases 138 1e-32
Hs16357482 [R] KOG0663 Protein kinase PITSLRE and related kinases 138 1e-32
Hs16357480 [R] KOG0663 Protein kinase PITSLRE and related kinases 138 1e-32
CE09532 [G] KOG0658 Glycogen synthase kinase-3 138 1e-32
CE05866 [G] KOG0658 Glycogen synthase kinase-3 138 1e-32
At1g54610 [D] KOG0600 Cdc2-related protein kinase 138 1e-32
At5g39420 [D] KOG0600 Cdc2-related protein kinase 137 2e-32
7297680 [R] KOG0594 Protein kinase PCTAIRE and related kinases 137 2e-32
Hs21237745 [T] KOG0665 Jun-N-terminal kinase (JNK) 137 3e-32
Hs21237742 [T] KOG0665 Jun-N-terminal kinase (JNK) 137 3e-32
Hs16357496 [R] KOG0663 Protein kinase PITSLRE and related kinases 137 3e-32
Hs16332372 [R] KOG0663 Protein kinase PITSLRE and related kinases 137 3e-32
Hs16332370 [R] KOG0663 Protein kinase PITSLRE and related kinases 137 3e-32
Hs16332368 [R] KOG0663 Protein kinase PITSLRE and related kinases 137 3e-32
Hs16332366 [R] KOG0663 Protein kinase PITSLRE and related kinases 137 3e-32
Hs16332364 [R] KOG0663 Protein kinase PITSLRE and related kinases 137 3e-32
Hs16332362 [R] KOG0663 Protein kinase PITSLRE and related kinases 137 3e-32
Hs16332360 [R] KOG0663 Protein kinase PITSLRE and related kinases 137 3e-32
Hs16332358 [R] KOG0663 Protein kinase PITSLRE and related kinases 137 3e-32
Hs10835055 [R] KOG0663 Protein kinase PITSLRE and related kinases 137 3e-32
At4g22940 [D] KOG0600 Cdc2-related protein kinase 137 3e-32
Hs4506785 [T] KOG0660 Mitogen-activated protein kinase 137 4e-32
YBR160w [R] KOG0594 Protein kinase PCTAIRE and related kinases 136 5e-32
Hs7706445 [T] KOG0664 Nemo-like MAPK-related serine/threonine pr... 136 5e-32
Hs5453860 [R] KOG0594 Protein kinase PCTAIRE and related kinases 136 5e-32
Hs15011928 [R] KOG0594 Protein kinase PCTAIRE and related kinases 136 5e-32
At1g74330 [D] KOG0600 Cdc2-related protein kinase 136 7e-32
SPBC119.08 [T] KOG0660 Mitogen-activated protein kinase 135 9e-32
CE20258 [R] KOG0593 Predicted protein kinase KKIAMRE 135 9e-32
At1g18670 [D] KOG0600 Cdc2-related protein kinase 135 9e-32
Hs16160923 [R] KOG0594 Protein kinase PCTAIRE and related kinases 135 1e-31
At4g10010 [D] KOG0600 Cdc2-related protein kinase 135 1e-31
7296346 [R] KOG0663 Protein kinase PITSLRE and related kinases 134 2e-31
CE19302_1 [G] KOG0658 Glycogen synthase kinase-3 134 2e-31
YBL016w [T] KOG0660 Mitogen-activated protein kinase 134 3e-31
At5g63610 [K] KOG0666 Cyclin C-dependent kinase CDK8 134 3e-31
7295173 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 134 3e-31
YGR040w [T] KOG0660 Mitogen-activated protein kinase 133 4e-31
HsM20070143 [T] KOG0665 Jun-N-terminal kinase (JNK) 133 4e-31
Hs21237739 [T] KOG0665 Jun-N-terminal kinase (JNK) 133 4e-31
Hs21237736 [T] KOG0665 Jun-N-terminal kinase (JNK) 133 4e-31
CE28918 [R] KOG0594 Protein kinase PCTAIRE and related kinases 133 4e-31
SPAC31G5.09c [T] KOG0660 Mitogen-activated protein kinase 133 6e-31
CE01612 [G] KOG0658 Glycogen synthase kinase-3 133 6e-31
7298087 [T] KOG0660 Mitogen-activated protein kinase 132 7e-31
CE18608 [R] KOG0594 Protein kinase PCTAIRE and related kinases 131 2e-30
At5g64960 [D] KOG0600 Cdc2-related protein kinase 131 2e-30
At4g11330 [T] KOG0660 Mitogen-activated protein kinase 131 2e-30
At1g03740 [D] KOG0600 Cdc2-related protein kinase 131 2e-30
7297631 [T] KOG0665 Jun-N-terminal kinase (JNK) 131 2e-30
SPCC16C4.11 [R] KOG0594 Protein kinase PCTAIRE and related kinases 131 2e-30
Hs21040235 [R] KOG0594 Protein kinase PCTAIRE and related kinases 131 2e-30
CE21213 [UT] KOG0662 Cyclin-dependent kinase CDK5 131 2e-30
CE18009 [R] KOG0594 Protein kinase PCTAIRE and related kinases 131 2e-30
At5g44290 [D] KOG0600 Cdc2-related protein kinase 131 2e-30
At5g10270 [D] KOG0600 Cdc2-related protein kinase 131 2e-30
YPR161c [D] KOG0600 Cdc2-related protein kinase 130 4e-30
SPAC3C7.06c [T] KOG0661 MAPK related serine/threonine protein ki... 130 4e-30
CE27574 [T] KOG0665 Jun-N-terminal kinase (JNK) 130 4e-30
SPBC32H8.10 [D] KOG0600 Cdc2-related protein kinase 130 5e-30
Hs20986512 [T] KOG0660 Mitogen-activated protein kinase 129 6e-30
At1g71530 [D] KOG0600 Cdc2-related protein kinase 129 6e-30
YPL031c [R] KOG0594 Protein kinase PCTAIRE and related kinases 129 8e-30
CE29612 [R] KOG0594 Protein kinase PCTAIRE and related kinases 129 8e-30
7301110 [T] KOG0660 Mitogen-activated protein kinase 129 1e-29
Hs4506091 [T] KOG0660 Mitogen-activated protein kinase 128 1e-29
CE01761 [R] KOG0663 Protein kinase PITSLRE and related kinases 127 2e-29
At1g09600 [D] KOG0600 Cdc2-related protein kinase 127 2e-29
Hs4503069 [T] KOG0660 Mitogen-activated protein kinase 127 3e-29
SPBC18H10.15 [R] KOG0663 Protein kinase PITSLRE and related kinases 127 4e-29
Hs6912584 [R] KOG0594 Protein kinase PCTAIRE and related kinases 126 5e-29
Hs4506081 [T] KOG0665 Jun-N-terminal kinase (JNK) 126 7e-29
Hs20986510 [T] KOG0665 Jun-N-terminal kinase (JNK) 126 7e-29
Hs20986506 [T] KOG0665 Jun-N-terminal kinase (JNK) 126 7e-29
Hs20502986 [T] KOG0660 Mitogen-activated protein kinase 126 7e-29
CE03811 [R] KOG0663 Protein kinase PITSLRE and related kinases 125 1e-28
Hs4503095 [TDK] KOG0668 Casein kinase II alpha subunit 124 3e-28
CE11556 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 124 3e-28
At2g23080 [TDK] KOG0668 Casein kinase II alpha subunit 124 3e-28
7291043 [T] KOG0660 Mitogen-activated protein kinase 124 3e-28
7289745 [TDK] KOG0668 Casein kinase II alpha subunit 124 3e-28
Hs20986514 [T] KOG0660 Mitogen-activated protein kinase 123 4e-28
Hs4506089 [T] KOG0660 Mitogen-activated protein kinase 123 6e-28
YPR054w [T] KOG0660 Mitogen-activated protein kinase 122 8e-28
Hs14110390 [D] KOG0600 Cdc2-related protein kinase 122 8e-28
Hs14110387 [D] KOG0600 Cdc2-related protein kinase 122 8e-28
ECU08g0230 [R] KOG0594 Protein kinase PCTAIRE and related kinases 122 8e-28
Hs20986516 [T] KOG0660 Mitogen-activated protein kinase 122 1e-27
CE29466 [T] KOG0665 Jun-N-terminal kinase (JNK) 122 1e-27
CE17062 [T] KOG0660 Mitogen-activated protein kinase 122 1e-27
7292375 [R] KOG0594 Protein kinase PCTAIRE and related kinases 122 1e-27
Hs20986521 [T] KOG0665 Jun-N-terminal kinase (JNK) 122 1e-27
Hs20986519 [T] KOG0665 Jun-N-terminal kinase (JNK) 122 1e-27
Hs7706549 [D] KOG0600 Cdc2-related protein kinase 121 2e-27
CE29318 [T] KOG0660 Mitogen-activated protein kinase 121 2e-27
CE17305 [T] KOG0665 Jun-N-terminal kinase (JNK) 121 2e-27
Hs7106269 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 121 2e-27
At1g57700 [D] KOG0600 Cdc2-related protein kinase 120 3e-27
YKL139w [D] KOG0600 Cdc2-related protein kinase 120 4e-27
Hs20986499 [T] KOG0660 Mitogen-activated protein kinase 120 4e-27
CE29073 [R] KOG0594 Protein kinase PCTAIRE and related kinases 120 4e-27
CE06779 [R] KOG0594 Protein kinase PCTAIRE and related kinases 120 4e-27
At5g67380 [TDK] KOG0668 Casein kinase II alpha subunit 120 4e-27
CE27220 [T] KOG0660 Mitogen-activated protein kinase 119 8e-27
At2g23070 [TDK] KOG0668 Casein kinase II alpha subunit 119 8e-27
Hs4506095 [T] KOG0665 Jun-N-terminal kinase (JNK) 119 1e-26
Hs20986523 [T] KOG0665 Jun-N-terminal kinase (JNK) 119 1e-26
YOR061w [TDK] KOG0668 Casein kinase II alpha subunit 118 1e-26
SPAC1E11.03 [R] KOG0667 Dual-specificity tyrosine-phosphorylatio... 118 1e-26
7294866 [K] KOG0666 Cyclin C-dependent kinase CDK8 118 1e-26
Hs4502741 [R] KOG0594 Protein kinase PCTAIRE and related kinases 118 2e-26
CE17321 [TDK] KOG0668 Casein kinase II alpha subunit 118 2e-26
YKL161c [T] KOG0660 Mitogen-activated protein kinase 117 4e-26
SPBC8D2.19 [T] KOG0661 MAPK related serine/threonine protein kinase 117 4e-26
Hs5921999 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 116 7e-26
Hs4502745 [K] KOG0666 Cyclin C-dependent kinase CDK8 115 9e-26
ECU05g1510 [TDK] KOG0668 Casein kinase II alpha subunit 115 1e-25
At3g50000 [TDK] KOG0668 Casein kinase II alpha subunit 115 1e-25
YPL042c [K] KOG0666 Cyclin C-dependent kinase CDK8 115 2e-25
YJL141c [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 115 2e-25
ECU08g1790 [D] KOG0600 Cdc2-related protein kinase 115 2e-25
7298142 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 114 2e-25
Hs5922004 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 114 3e-25
Hs4503427 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 114 3e-25
Hs17452757 [UT] KOG0662 Cyclin-dependent kinase CDK5 114 3e-25
Hs4503097 [TDK] KOG0668 Casein kinase II alpha subunit 113 5e-25
Hs20551615 [K] KOG0666 Cyclin C-dependent kinase CDK8 113 5e-25
Hs5922001 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 113 6e-25
7302908 [R] KOG0594 Protein kinase PCTAIRE and related kinases 113 6e-25
ECU02g1450 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymer... 112 8e-25
CE04430 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 112 8e-25
SPAC2F3.15 [D] KOG0600 Cdc2-related protein kinase 112 1e-24
Hs4503429 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 111 2e-24
At5g35980 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 111 2e-24
CE06352 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 111 2e-24
Hs4758222 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 110 3e-24
Hs4502735 [R] KOG0594 Protein kinase PCTAIRE and related kinases 110 4e-24
ECU11g0960 [D] KOG0600 Cdc2-related protein kinase 109 7e-24
ECU11g0180 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 109 7e-24
YJL106w [T] KOG0661 MAPK related serine/threonine protein kinase 108 1e-23
Hs4502747 [D] KOG0669 Cyclin T-dependent kinase CDK9 108 1e-23
7291976 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 108 1e-23
YIL035c [TDK] KOG0668 Casein kinase II alpha subunit 108 1e-23
CE17815 [K] KOG0666 Cyclin C-dependent kinase CDK8 108 1e-23
CE26422 [D] KOG0600 Cdc2-related protein kinase 108 2e-23
SPAC2F7.03c [R] KOG0667 Dual-specificity tyrosine-phosphorylatio... 107 4e-23
Hs16306492 [R] KOG0594 Protein kinase PCTAIRE and related kinases 107 4e-23
Hs21389587 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 106 6e-23
CE23605 [T] KOG0665 Jun-N-terminal kinase (JNK) 106 6e-23
Hs20550209 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 105 1e-22
CE23751 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 105 1e-22
CE19878 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 105 1e-22
CE05897 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 105 1e-22
7291932 [A] KOG0670 U4/U6-associated splicing factor PRP4 105 1e-22
7296451 [D] KOG0600 Cdc2-related protein kinase 105 2e-22
Hs18765758 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 104 2e-22
Hs18765756 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 104 2e-22
Hs18765754 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 104 2e-22
Hs18765752 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 104 2e-22
Hs18765750 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 104 2e-22
7291442 [D] KOG0669 Cyclin T-dependent kinase CDK9 104 2e-22
At2g40120 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 104 3e-22
At1g08650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 104 3e-22
ECU11g1290 [R] KOG0663 Protein kinase PITSLRE and related kinases 103 6e-22
At3g17750 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 103 6e-22
Hs20986508 [T] KOG0665 Jun-N-terminal kinase (JNK) 102 8e-22
SPCC777.14 [A] KOG0670 U4/U6-associated splicing factor PRP4 102 1e-21
At1g53570 [T] KOG0198 MEKK and related serine/threonine protein ... 102 1e-21
SPAC23H4.17c [K] KOG0666 Cyclin C-dependent kinase CDK8 101 2e-21
CE19219 [T] KOG0665 Jun-N-terminal kinase (JNK) 101 2e-21
At1g73460 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 101 2e-21
Hs17999535 [A] KOG0670 U4/U6-associated splicing factor PRP4 101 2e-21
CE23826 [D] KOG0669 Cyclin T-dependent kinase CDK9 101 2e-21
At3g04530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 101 2e-21
At1g50230 [R] KOG0597 Serine-threonine protein kinase FUSED 101 2e-21
CE18824 [D] KOG0669 Cyclin T-dependent kinase CDK9 100 3e-21
SPBC21.06c [T] KOG0198 MEKK and related serine/threonine protein... 100 4e-21
At3g25840 [A] KOG0670 U4/U6-associated splicing factor PRP4 100 4e-21
Hs13430860 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 100 7e-21
At3g61960 [OUT] KOG0595 Serine/threonine-protein kinase involved... 99 9e-21
At3g53640 [A] KOG0670 U4/U6-associated splicing factor PRP4 99 9e-21
SPAC23C11.11 [TDK] KOG0668 Casein kinase II alpha subunit 99 1e-20
At3g08730 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 99 2e-20
Hs18552621 [R] KOG0597 Serine-threonine protein kinase FUSED 98 3e-20
SPAC1D4.11c [T] KOG0671 LAMMER dual specificity kinases 97 3e-20
At3g08720 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 97 3e-20
At2g37840 [OUT] KOG0595 Serine/threonine-protein kinase involved... 97 3e-20
CE19749 [T] KOG0665 Jun-N-terminal kinase (JNK) 97 4e-20
Hs4759050 [T] KOG0603 Ribosomal protein S6 kinase 97 6e-20
Hs11386209 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 97 6e-20
CE18169 [T] KOG0603 Ribosomal protein S6 kinase 96 1e-19
CE13014 [T] KOG0603 Ribosomal protein S6 kinase 96 1e-19
SPAC9G1.02 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 an... 95 2e-19
Hs16936530 [R] KOG0594 Protein kinase PCTAIRE and related kinases 94 4e-19
At1g13350 [A] KOG0670 U4/U6-associated splicing factor PRP4 94 4e-19
At1g73450 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 94 5e-19
At1g49180_1 [OUT] KOG0595 Serine/threonine-protein kinase involv... 94 5e-19
SPAC23C11.16 [D] KOG0575 Polo-like serine/threonine protein kinase 92 1e-18
At1g63700 [T] KOG0198 MEKK and related serine/threonine protein ... 92 1e-18
YPL153c [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 91 2e-18
Hs22045050 [T] KOG0671 LAMMER dual specificity kinases 91 2e-18
7302464 [R] KOG0586 Serine/threonine protein kinase 91 2e-18
Hs7657526 [T] KOG0603 Ribosomal protein S6 kinase 91 3e-18
At1g12580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 91 3e-18
Hs19923570 [T] KOG0603 Ribosomal protein S6 kinase 91 4e-18
CE05686 [A] KOG0670 U4/U6-associated splicing factor PRP4 91 4e-18
Hs20149547 [T] KOG0603 Ribosomal protein S6 kinase 90 5e-18
SPCC18B5.11c [D] KOG0615 Serine/threonine protein kinase Chk2 an... 90 7e-18
Hs4758702 [T] KOG4279 Serine/threonine protein kinase 89 9e-18
Hs20538863 [T] KOG4250 TANK binding protein kinase TBK1 89 9e-18
Hs4758008 [T] KOG0671 LAMMER dual specificity kinases 89 1e-17
7296450 [D] KOG0575 Polo-like serine/threonine protein kinase 89 1e-17
7293496 [R] KOG0597 Serine-threonine protein kinase FUSED 89 1e-17
7290841 [D] KOG0591 NIMA (never in mitosis)-related G2-specific ... 89 1e-17
Hs7662210 [OUT] KOG0595 Serine/threonine-protein kinase involved... 89 2e-17
CE27768 [R] KOG0586 Serine/threonine protein kinase 89 2e-17
CE23838 [R] KOG0586 Serine/threonine protein kinase 89 2e-17
YPL209c [D] KOG0580 Serine/threonine protein kinase 88 2e-17
CE27297 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 88 2e-17
At3g06030 [T] KOG0198 MEKK and related serine/threonine protein ... 88 2e-17
At1g09000 [T] KOG0198 MEKK and related serine/threonine protein ... 88 2e-17
7299536 [D] KOG0580 Serine/threonine protein kinase 88 2e-17
SPBC1D7.05c [T] KOG0198 MEKK and related serine/threonine protei... 88 3e-17
CE28251 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 88 3e-17
CE10328 [T] KOG1006 Mitogen-activated protein kinase (MAPK) kina... 88 3e-17
At1g54960 [T] KOG0198 MEKK and related serine/threonine protein ... 88 3e-17
Hs4505695 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 87 3e-17
Hs20479818 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 87 3e-17
Hs4507831 [OUT] KOG0595 Serine/threonine-protein kinase involved... 87 5e-17
7292679 [G] KOG0599 Phosphorylase kinase gamma subunit 87 5e-17
CE27177 [T] KOG4279 Serine/threonine protein kinase 86 8e-17
7303211 [T] KOG4717 Serine/threonine protein kinase 86 8e-17
Hs5453882 [G] KOG0599 Phosphorylase kinase gamma subunit 86 1e-16
Hs14728804 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 86 1e-16
7293666 [D] KOG0575 Polo-like serine/threonine protein kinase 86 1e-16
SPBC4C3.11 [T] KOG0592 3-phosphoinositide-dependent protein kina... 86 1e-16
Hs10190706 [T] KOG0671 LAMMER dual specificity kinases 86 1e-16
CE15235 [R] KOG0589 Serine/threonine protein kinase 86 1e-16
YKL101w [D] KOG0588 Serine/threonine protein kinase 85 2e-16
YDL101c [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 85 2e-16
Hs21361643 [T] KOG4717 Serine/threonine protein kinase 85 2e-16
SPCC24B10.07 [RT] KOG0598 Ribosomal protein S6 kinase and relate... 85 2e-16
7299438 [R] KOG0586 Serine/threonine protein kinase 85 2e-16
Hs4507277_1 [R] KOG0589 Serine/threonine protein kinase 85 2e-16
ECU11g1500 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 84 3e-16
CE07285 [D] KOG0575 Polo-like serine/threonine protein kinase 84 3e-16
At3g29160 [T] KOG0583 Serine/threonine protein kinase 84 3e-16
YOL100w [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 84 4e-16
CE24761 [D] KOG0580 Serine/threonine protein kinase 84 4e-16
7300559 [T] KOG4279 Serine/threonine protein kinase 84 4e-16
7295638 [T] KOG0603 Ribosomal protein S6 kinase 84 4e-16
SPAC1F3.02c [T] KOG0198 MEKK and related serine/threonine protei... 84 5e-16
At3g13530 [T] KOG0198 MEKK and related serine/threonine protein ... 84 5e-16
7290249 [R] KOG0586 Serine/threonine protein kinase 84 5e-16
Hs4506735 [T] KOG0603 Ribosomal protein S6 kinase 83 7e-16
CE21615 [T] KOG0578 p21-activated serine/threonine protein kinase 83 7e-16
At4g28980 [R] KOG0594 Protein kinase PCTAIRE and related kinases 83 7e-16
SPCC320.12c [D] KOG0580 Serine/threonine protein kinase 83 9e-16
HsM5729922 [T] KOG0198 MEKK and related serine/threonine protein... 83 9e-16
Hs8923922 [R] KOG0586 Serine/threonine protein kinase 83 9e-16
Hs19424132 [D] KOG0591 NIMA (never in mitosis)-related G2-specif... 83 9e-16
At3g01090 [T] KOG0583 Serine/threonine protein kinase 83 9e-16
YDR490c [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 82 1e-15
HsM4505103 [R] KOG0586 Serine/threonine protein kinase 82 1e-15
Hs7662170 [R] KOG0611 Predicted serine/threonine protein kinase 82 1e-15
Hs15619015 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 82 1e-15
CE28744 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 82 1e-15
7299437 [R] KOG0586 Serine/threonine protein kinase 82 1e-15
7293601 [T] KOG0577 Serine/threonine protein kinase 82 1e-15
HsM8923212 [T] KOG4717 Serine/threonine protein kinase 82 1e-15
Hs9845489 [R] KOG0586 Serine/threonine protein kinase 82 1e-15
Hs9845487 [R] KOG0586 Serine/threonine protein kinase 82 1e-15
Hs4505153 [T] KOG0198 MEKK and related serine/threonine protein ... 82 1e-15
Hs22062450 [R] KOG0586 Serine/threonine protein kinase 82 1e-15
CE22877 [D] KOG0575 Polo-like serine/threonine protein kinase 82 1e-15
At1g12680 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 82 1e-15
Hs4758016 [D] KOG0575 Polo-like serine/threonine protein kinase 82 2e-15
Hs4507273 [D] KOG0580 Serine/threonine protein kinase 82 2e-15
Hs4506055 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 82 2e-15
CE18454 [T] KOG4717 Serine/threonine protein kinase 82 2e-15
At4g32660 [T] KOG0671 LAMMER dual specificity kinases 82 2e-15
At1g61950 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 82 2e-15
HsM7657627 [D] KOG0575 Polo-like serine/threonine protein kinase 81 3e-15
Hs21735556 [T] KOG0198 MEKK and related serine/threonine protein... 81 3e-15
Hs14771959 [T] KOG0578 p21-activated serine/threonine protein ki... 81 3e-15
Hs14754789 [OUT] KOG0595 Serine/threonine-protein kinase involve... 81 3e-15
7294217 [D] KOG0588 Serine/threonine protein kinase 81 3e-15
CE24993 [D] KOG0669 Cyclin T-dependent kinase CDK9 81 3e-15
SPAC644.06c [D] KOG0588 Serine/threonine protein kinase 80 4e-15
At2g35890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 80 4e-15
At2g30360 [T] KOG0583 Serine/threonine protein kinase 80 4e-15
7297542 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 80 4e-15
YJL095w [T] KOG0198 MEKK and related serine/threonine protein ki... 80 6e-15
YDR477w [T] KOG0583 Serine/threonine protein kinase 80 6e-15
SPCC63.08c [OUT] KOG0595 Serine/threonine-protein kinase involve... 80 6e-15
Hs5174547 [T] KOG4279 Serine/threonine protein kinase 80 6e-15
Hs4759178 [D] KOG0580 Serine/threonine protein kinase 80 6e-15
At5g19450 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 80 6e-15
At2g41860 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 80 6e-15
YHR205w [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 80 7e-15
YGL180w [OUT] KOG0595 Serine/threonine-protein kinase involved i... 80 7e-15
Hs4505599 [T] KOG0578 p21-activated serine/threonine protein kinase 80 7e-15
Hs21361433 [D] KOG0575 Polo-like serine/threonine protein kinase 80 7e-15
CE15475 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 80 7e-15
CE15473 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 80 7e-15
CE12518 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 80 7e-15
CE05780 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 80 7e-15
CE03467 [T] KOG0604 MAP kinase-activated protein kinase 2 80 7e-15
SPCC576.15c [T] KOG0592 3-phosphoinositide-dependent protein kin... 79 1e-14
Hs19923468 [T] KOG4236 Serine/threonine protein kinase PKC mu/PK... 79 1e-14
Hs14993776 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 79 1e-14
Hs14777335 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 79 1e-14
CE28218 [D] KOG0588 Serine/threonine protein kinase 79 1e-14
7300435 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and r... 79 1e-14
7298926 [T] KOG0578 p21-activated serine/threonine protein kinase 79 1e-14
Hs20070247_2 [RT] KOG0598 Ribosomal protein S6 kinase and relate... 79 1e-14
YOL016c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 79 1e-14
YLR362w [T] KOG0198 MEKK and related serine/threonine protein ki... 79 1e-14
SPAC19E9.02 [D] KOG0591 NIMA (never in mitosis)-related G2-speci... 79 1e-14
Hs7657214 [T] KOG0583 Serine/threonine protein kinase 79 1e-14
Hs5453964 [T] KOG0583 Serine/threonine protein kinase 79 1e-14
Hs4507275 [D] KOG0580 Serine/threonine protein kinase 79 1e-14
CE01554 [T] KOG0986 G protein-coupled receptor kinase 79 1e-14
Hs5730055 [D] KOG0575 Polo-like serine/threonine protein kinase 79 2e-14
Hs22057171 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 79 2e-14
CE17343 [T] KOG0583 Serine/threonine protein kinase 79 2e-14
At5g16500 [T] KOG1187 Serine/threonine protein kinase 79 2e-14
At1g11050 [T] KOG1187 Serine/threonine protein kinase 79 2e-14
7290150 [T] KOG0583 Serine/threonine protein kinase 79 2e-14
YOR351c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 78 2e-14
YAR019c [T] KOG0198 MEKK and related serine/threonine protein ki... 78 2e-14
SPCC74.03c [T] KOG0583 Serine/threonine protein kinase 78 2e-14
SPAC1B9.02c [RT] KOG0598 Ribosomal protein S6 kinase and related... 78 2e-14
Hs13899225 [R] KOG0586 Serine/threonine protein kinase 78 2e-14
Hs13489054 [T] KOG0581 Mitogen-activated protein kinase kinase (... 78 2e-14
CE06635 [Z] KOG0613 Projectin/twitchin and related proteins 78 2e-14
CE06634 [Z] KOG0613 Projectin/twitchin and related proteins 78 2e-14
At5g66850 [T] KOG0198 MEKK and related serine/threonine protein ... 78 2e-14
YCL024w [T] KOG0583 Serine/threonine protein kinase 78 3e-14
Hs5453966 [T] KOG0583 Serine/threonine protein kinase 78 3e-14
Hs4505785 [G] KOG0599 Phosphorylase kinase gamma subunit 78 3e-14
Hs20545245 [D] KOG0588 Serine/threonine protein kinase 78 3e-14
Hs14770402 [R] KOG0586 Serine/threonine protein kinase 78 3e-14
CE01405 [T] KOG0577 Serine/threonine protein kinase 78 3e-14
At4g24740 [T] KOG0671 LAMMER dual specificity kinases 78 3e-14
At3g07980 [T] KOG0198 MEKK and related serine/threonine protein ... 78 3e-14
At3g02810 [T] KOG1187 Serine/threonine protein kinase 78 3e-14
At1g78530 [T] KOG1187 Serine/threonine protein kinase 78 3e-14
At1g54510 [R] KOG0589 Serine/threonine protein kinase 78 3e-14
Hs7706601 [T] KOG0192 Tyrosine kinase specific for activated (GT... 77 4e-14
Hs6031180 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and... 77 4e-14
Hs5803088 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and... 77 4e-14
Hs20127541 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 77 4e-14
Hs19526767 [T] KOG0192 Tyrosine kinase specific for activated (G... 77 4e-14
CE26649 [D] KOG0575 Polo-like serine/threonine protein kinase 77 4e-14
CE14798 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 77 4e-14
CE03492 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 77 4e-14
7299160 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 77 4e-14
7294537 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 77 4e-14
7290147 [T] KOG0583 Serine/threonine protein kinase 77 4e-14
Hs22050308_2 [T] KOG0198 MEKK and related serine/threonine prote... 77 4e-14
YKL126w [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 77 5e-14
YFR014c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 77 5e-14
SPCC4G3.08 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 77 5e-14
SPAC57A10.02 [D] KOG0588 Serine/threonine protein kinase 77 5e-14
Hs5174701 [T] KOG0579 Ste20-like serine/threonine protein kinase 77 5e-14
Hs4506075 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD... 77 5e-14
Hs4506057 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 77 5e-14
Hs21166359 [T] KOG0986 G protein-coupled receptor kinase 77 5e-14
At4g30960 [T] KOG0583 Serine/threonine protein kinase 77 5e-14
At4g23650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 77 5e-14
SPAC1F5.09c [T] KOG0578 p21-activated serine/threonine protein k... 77 6e-14
Hs8923754 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 77 6e-14
Hs7706401 [T] KOG0577 Serine/threonine protein kinase 77 6e-14
Hs6005850 [D] KOG0615 Serine/threonine protein kinase Chk2 and r... 77 6e-14
Hs5031689 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD... 77 6e-14
Hs4759208 [T] KOG0577 Serine/threonine protein kinase 77 6e-14
CE22045 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 77 6e-14
CE04172 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 77 6e-14
At4g04720 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 77 6e-14
At3g24790 [T] KOG1187 Serine/threonine protein kinase 77 6e-14
7301213 [R] KOG0589 Serine/threonine protein kinase 77 6e-14
7299793 [T] KOG0583 Serine/threonine protein kinase 77 6e-14
>YMR139w [G] KOG0658 Glycogen synthase kinase-3
Length = 370
Score = 448 bits (1152), Expect = e-126
Identities = 222/339 (65%), Positives = 272/339 (79%), Gaps = 5/339 (1%)
Query: 78 NPEESVVISCGTPEIVGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKNRELEIMKLISH 137
+P + V IS T E+VG+GSFGVVF T ++ET E V IKKVLQD+RFKNRELEIMK++SH
Sbjct: 30 DPNDPVQISFPTTEVVGHGSFGVVFATVIQETNEKVAIKKVLQDKRFKNRELEIMKMLSH 89
Query: 138 PNLIDLKYYFLEQSDQ-ELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFK 196
N+IDLKY+F E+ Q E+YLNLI++YMP SLYQRL+ F+ PM R EIK YMFQLFK
Sbjct: 90 INIIDLKYFFYERDSQDEIYLNLILEYMPQSLYQRLRHFVHQRTPMSRLEIKYYMFQLFK 149
Query: 197 SLNYLHQVVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPE 256
SLNYLH NVCHRDIKPQN+LVDP+T LK+CD GSAKQLKP EPNVSYICSRYYRAPE
Sbjct: 150 SLNYLHHFANVCHRDIKPQNLLVDPETWSLKLCDFGSAKQLKPTEPNVSYICSRYYRAPE 209
Query: 257 LIFGATNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNE 316
LIFGATNYT +IDIWS+GCVMAELLLGQP+FPGES IDQLVEIIK+LGTP+++EICSMN
Sbjct: 210 LIFGATNYTNQIDIWSSGCVMAELLLGQPMFPGESGIDQLVEIIKILGTPSKQEICSMNP 269
Query: 317 NYSEHKFPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSALQCMFNSTYFTDIVSN 376
NY EHKFPQI+PIPL+R+FKKE +T++ L ++KYDP R++ALQC+ S YF ++ +
Sbjct: 270 NYMEHKFPQIKPIPLSRVFKKEDDQTVEFLADVLKYDPLERFNALQCLC-SPYFDELKLD 328
Query: 377 TGSDSNLSLIDSLPLLHFEES-ELQGLSSNDIYRLTGKL 414
G + ++ L LL F+E+ EL LS +++ + KL
Sbjct: 329 DGKINQIT--TDLKLLEFDENVELGHLSPDELSSVKKKL 365
>YDL079c [G] KOG0658 Glycogen synthase kinase-3
Length = 501
Score = 377 bits (968), Expect = e-104
Identities = 180/292 (61%), Positives = 227/292 (77%), Gaps = 2/292 (0%)
Query: 82 SVVISCGTPEIVGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKNRELEIMKLISHPNLI 141
++ IS T E+VG+GSFGVV T + ET + V IKKVLQDRR+KNRELE MK++ HPN +
Sbjct: 159 TIDISYPTTEVVGHGSFGVVVTTVIIETNQKVAIKKVLQDRRYKNRELETMKMLCHPNTV 218
Query: 142 DLKYYFLEQSDQ-ELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNY 200
L+YYF E+ ++ E+YLNL++DYMP SLYQRL+ F++L M R EIK Y +QLFK+LNY
Sbjct: 219 GLQYYFYEKDEEDEVYLNLVLDYMPQSLYQRLRHFVNLKMQMPRVEIKFYAYQLFKALNY 278
Query: 201 LHQVVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFG 260
LH V +CHRDIKPQN+LVDP T KICD GSAK LKP++PNVSYICSRYYRAPEL+FG
Sbjct: 279 LHNVPRICHRDIKPQNLLVDPTTFSFKICDFGSAKCLKPDQPNVSYICSRYYRAPELMFG 338
Query: 261 ATNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENYSE 320
ATNY+ ++D+WS+ CV+AELLLG+P+F GES IDQLVEIIK++G PT++EI MN NY +
Sbjct: 339 ATNYSNQVDVWSSACVIAELLLGKPLFSGESGIDQLVEIIKIMGIPTKDEISGMNPNYED 398
Query: 321 HKFPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSALQCMFNSTYFTD 372
H FP I+PI L IFK E +T+DLL +KY P R LQC+ S+YF +
Sbjct: 399 HVFPNIKPITLAEIFKAEDPDTLDLLTKTLKYHPCERLVPLQCLL-SSYFDE 449
>At4g00720 [G] KOG0658 Glycogen synthase kinase-3
Length = 472
Score = 361 bits (927), Expect = e-99
Identities = 187/345 (54%), Positives = 245/345 (70%), Gaps = 11/345 (3%)
Query: 71 TVVKGHSNPEESVVISCGTPEIVGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKNRELE 130
T G + + IS +VG GSFGVVF+ K ETGE V IKKVLQD+R+KNREL+
Sbjct: 122 TTTVGGRDGKPKQTISYMAQRVVGTGSFGVVFQAKCLETGEQVAIKKVLQDKRYKNRELQ 181
Query: 131 IMKLISHPNLIDLKYYFLEQSDQ-ELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKI 189
IM+L HPN++ L++ F +D+ ELYLNL+++Y+P ++Y+ K + ++Q M +++
Sbjct: 182 IMRLQDHPNVVRLRHSFFSTTDKDELYLNLVLEYVPETVYRASKHYTKMNQHMPIIFVQL 241
Query: 190 YMFQLFKSLNYLHQVVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICS 249
Y +Q+ ++LNYLH+VV VCHRDIKPQN+LV+P T LKICD GSAK L P EPN+SYICS
Sbjct: 242 YTYQICRALNYLHRVVGVCHRDIKPQNLLVNPQTHQLKICDFGSAKMLVPGEPNISYICS 301
Query: 250 RYYRAPELIFGATNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTRE 309
RYYRAPELIFGAT YT ID+WS GCVMAELLLGQP+FPGES IDQLVEIIK+LGTPTRE
Sbjct: 302 RYYRAPELIFGATEYTNAIDMWSGGCVMAELLLGQPLFPGESGIDQLVEIIKILGTPTRE 361
Query: 310 EICSMNENYSEHKFPQIRPIPLNRIF-KKETQETIDLLYHIMKYDPNIRYSALQCMFNST 368
EI MN NY+E KFPQI+ P ++IF K+ E +DL+ +++Y PN+R +AL+ +
Sbjct: 362 EIRCMNPNYTEFKFPQIKAHPWHKIFHKRMPPEAVDLVSRLLQYSPNLRCTALEACAH-P 420
Query: 369 YFTDIVSNTGSDSNLSLIDSL---PLLHFEESELQGLSSNDIYRL 410
+F D+ D N+SL + PL +F EL G S+ RL
Sbjct: 421 FFDDL-----RDPNVSLPNGRALPPLFNFTAQELAGASTELRQRL 460
>At3g05840 [G] KOG0658 Glycogen synthase kinase-3
Length = 409
Score = 357 bits (917), Expect = 1e-98
Identities = 178/338 (52%), Positives = 245/338 (71%), Gaps = 5/338 (1%)
Query: 75 GHSNPEESVVISCGTPEIVGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKNRELEIMKL 134
G N + IS +VG+GSFGVVF+ K ETGE V IKKVLQDRR+KNREL+ M+L
Sbjct: 61 GGRNGQPKQTISYMAERVVGHGSFGVVFQAKCLETGETVAIKKVLQDRRYKNRELQTMRL 120
Query: 135 ISHPNLIDLKYYFLEQSDQ-ELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQ 193
+ HPN++ LK+ F +++ ELYLNL+++Y+P ++++ +K + L+Q M +K+Y +Q
Sbjct: 121 LDHPNVVSLKHCFFSTTEKDELYLNLVLEYVPETVHRVIKHYNKLNQRMPLVYVKLYTYQ 180
Query: 194 LFKSLNYLHQVVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYR 253
+F+SL+Y+H+ + VCHRDIKPQN+LV+P T +K+CD GSAK L EPN+SYICSRYYR
Sbjct: 181 IFRSLSYIHRCIGVCHRDIKPQNLLVNPHTHQVKLCDFGSAKVLVKGEPNISYICSRYYR 240
Query: 254 APELIFGATNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICS 313
APELIFGAT YTT ID+WSAGCV+AELLLGQP+FPGES +DQLVEIIKVLGTPTREEI
Sbjct: 241 APELIFGATEYTTAIDVWSAGCVLAELLLGQPLFPGESGVDQLVEIIKVLGTPTREEIKC 300
Query: 314 MNENYSEHKFPQIRPIPLNRIF-KKETQETIDLLYHIMKYDPNIRYSALQCMFNSTYFTD 372
MN NY+E KFPQI+ P ++IF K+ E +DL+ +++Y PN+R +AL + + +F +
Sbjct: 301 MNPNYTEFKFPQIKAHPWHKIFHKRMPPEAVDLVSRLLQYSPNLRCAALDSLVH-PFFDE 359
Query: 373 IVSNTGSDSNLSLIDSLPLLHFEESELQGLSSNDIYRL 410
+ N + PL +F+ EL+G+ + +L
Sbjct: 360 LRDPNARLPNGRFLP--PLFNFKPHELKGVPVEMVAKL 395
>At5g26751 [G] KOG0658 Glycogen synthase kinase-3
Length = 413
Score = 353 bits (905), Expect = 3e-97
Identities = 175/326 (53%), Positives = 240/326 (72%), Gaps = 19/326 (5%)
Query: 55 NDVKIVPDEDEVITRRTVVKGHSNPEESVVISC-----GTPE---------IVGNGSFGV 100
ND+KI D++ TVV G+ ++++ G P+ +VG+GSFGV
Sbjct: 26 NDMKIRDDKE---MEATVVDGNGTETGHIIVTTIGGRNGQPKQTISYMAERVVGHGSFGV 82
Query: 101 VFRTKVKETGEDVVIKKVLQDRRFKNRELEIMKLISHPNLIDLKYYFLEQSDQ-ELYLNL 159
VF+ K ETGE V IKKVLQDRR+KNREL+ M+L+ HPN++ LK+ F +++ ELYLNL
Sbjct: 83 VFQAKCLETGETVAIKKVLQDRRYKNRELQTMRLLDHPNVVSLKHCFFSTTEKDELYLNL 142
Query: 160 IVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVVNVCHRDIKPQNILV 219
+++Y+P ++++ +K + L+Q M +K+Y +Q+F++L+Y+H+ + VCHRDIKPQN+LV
Sbjct: 143 VLEYVPETVHRVIKHYNKLNQRMPLIYVKLYTYQIFRALSYIHRCIGVCHRDIKPQNLLV 202
Query: 220 DPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGATNYTTKIDIWSAGCVMAE 279
+P T +K+CD GSAK L EPN+SYICSRYYRAPELIFGAT YTT ID+WSAGCV+AE
Sbjct: 203 NPHTHQVKLCDFGSAKVLVKGEPNISYICSRYYRAPELIFGATEYTTAIDVWSAGCVLAE 262
Query: 280 LLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENYSEHKFPQIRPIPLNRIF-KKE 338
LLLGQP+FPGES +DQLVEIIKVLGTPTREEI MN NY+E KFPQI+ P ++IF K+
Sbjct: 263 LLLGQPLFPGESGVDQLVEIIKVLGTPTREEIKCMNPNYTEFKFPQIKAHPWHKIFHKRM 322
Query: 339 TQETIDLLYHIMKYDPNIRYSALQCM 364
E +DL+ +++Y PN+R +AL +
Sbjct: 323 PPEAVDLVSRLLQYSPNLRSAALDTL 348
>At4g18710 [G] KOG0658 Glycogen synthase kinase-3
Length = 380
Score = 347 bits (890), Expect = 2e-95
Identities = 169/290 (58%), Positives = 220/290 (75%), Gaps = 2/290 (0%)
Query: 75 GHSNPEESVVISCGTPEIVGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKNRELEIMKL 134
G N E IS +VG GSFG+VF+ K ETGE V IKKVLQDRR+KNREL++M++
Sbjct: 28 GGKNGEPKQTISYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKNRELQLMRV 87
Query: 135 ISHPNLIDLKY-YFLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQ 193
+ HPN++ LK+ +F S EL+LNL+++Y+P SLY+ LK + S +Q M +K+YM+Q
Sbjct: 88 MDHPNVVCLKHCFFSTTSKDELFLNLVMEYVPESLYRVLKHYSSANQRMPLVYVKLYMYQ 147
Query: 194 LFKSLNYLHQVVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYR 253
+F+ L Y+H V VCHRD+KPQN+LVDP T +KICD GSAKQL E N+SYICSR+YR
Sbjct: 148 IFRGLAYIHNVAGVCHRDLKPQNLLVDPLTHQVKICDFGSAKQLVKGEANISYICSRFYR 207
Query: 254 APELIFGATNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICS 313
APELIFGAT YTT IDIWSAGCV+AELLLGQP+FPGE+ +DQLVEIIKVLGTPTREEI
Sbjct: 208 APELIFGATEYTTSIDIWSAGCVLAELLLGQPLFPGENAVDQLVEIIKVLGTPTREEIRC 267
Query: 314 MNENYSEHKFPQIRPIPLNRIF-KKETQETIDLLYHIMKYDPNIRYSALQ 362
MN +Y++ +FPQI+ P ++IF K+ E ID +++Y P++R +AL+
Sbjct: 268 MNPHYTDFRFPQIKAHPWHKIFHKRMPPEAIDFASRLLQYSPSLRCTALE 317
>At1g06390 [G] KOG0658 Glycogen synthase kinase-3
Length = 407
Score = 347 bits (890), Expect = 2e-95
Identities = 180/340 (52%), Positives = 237/340 (68%), Gaps = 10/340 (2%)
Query: 75 GHSNPEESVVISCGTPEIVGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKNRELEIMKL 134
G N E IS +VG GSFG+VF+ K ETGE V IKKVLQDRR+KNREL++M+
Sbjct: 58 GGKNGEPKQTISYMAERVVGTGSFGIVFQAKCLETGESVAIKKVLQDRRYKNRELQLMRP 117
Query: 135 ISHPNLIDLKY-YFLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQ 193
+ HPN+I LK+ +F S EL+LNL+++Y+P +LY+ L+ + S +Q M + +K+Y +Q
Sbjct: 118 MDHPNVISLKHCFFSTTSRDELFLNLVMEYVPETLYRVLRHYTSSNQRMPIFYVKLYTYQ 177
Query: 194 LFKSLNYLHQVVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYR 253
+F+ L Y+H V VCHRD+KPQN+LVDP T +K+CD GSAK L EPN+SYICSRYYR
Sbjct: 178 IFRGLAYIHTVPGVCHRDVKPQNLLVDPLTHQVKLCDFGSAKVLVKGEPNISYICSRYYR 237
Query: 254 APELIFGATNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICS 313
APELIFGAT YT IDIWSAGCV+AELLLGQP+FPGE+ +DQLVEIIKVLGTPTREEI
Sbjct: 238 APELIFGATEYTASIDIWSAGCVLAELLLGQPLFPGENSVDQLVEIIKVLGTPTREEIRC 297
Query: 314 MNENYSEHKFPQIRPIPLNRIF-KKETQETIDLLYHIMKYDPNIRYSALQCMFNSTYFTD 372
MN NY++ +FPQI+ P +++F K+ E IDL +++Y P++R +AL+ + +
Sbjct: 298 MNPNYTDFRFPQIKAHPWHKVFHKRMPPEAIDLASRLLQYSPSLRCTALEACAHPFF--- 354
Query: 373 IVSNTGSDSNLSLIDSLPL--LHFEESELQGLSSNDIYRL 410
N + N L + PL L + EL G S I RL
Sbjct: 355 ---NELREPNARLPNGRPLPPLFNFKQELGGASMELINRL 391
>At2g30980 [G] KOG0658 Glycogen synthase kinase-3
Length = 412
Score = 347 bits (889), Expect = 2e-95
Identities = 189/378 (50%), Positives = 248/378 (65%), Gaps = 26/378 (6%)
Query: 53 HGND-VKIVPDEDE-------VITRRTVVKGH--------SNPEESVVISCGTPEIVGNG 96
HG D +K PD D VI V GH N E IS +VG G
Sbjct: 22 HGGDSLKRRPDIDNDKEMSAAVIEGNDAVTGHIISTTIGGKNGEPKQTISYMAERVVGTG 81
Query: 97 SFGVVFRTKVKETGEDVVIKKVLQDRRFKNRELEIMKLISHPNLIDLKYYFLEQSDQ-EL 155
SFG+VF+ K ETGE V IKKVLQDRR+KNREL++M+L+ HPN++ LK+ F + + EL
Sbjct: 82 SFGIVFQAKCLETGESVAIKKVLQDRRYKNRELQLMRLMDHPNVVSLKHCFFSTTTRDEL 141
Query: 156 YLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVVNVCHRDIKPQ 215
+LNL+++Y+P +LY+ LK + S +Q M + +K+Y +Q+F+ L Y+H VCHRD+KPQ
Sbjct: 142 FLNLVMEYVPETLYRVLKHYTSSNQRMPIFYVKLYTYQIFRGLAYIHTAPGVCHRDVKPQ 201
Query: 216 NILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGATNYTTKIDIWSAGC 275
N+LVDP T K+CD GSAK L E N+SYICSRYYRAPELIFGAT YT+ IDIWSAGC
Sbjct: 202 NLLVDPLTHQCKLCDFGSAKVLVKGEANISYICSRYYRAPELIFGATEYTSSIDIWSAGC 261
Query: 276 VMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENYSEHKFPQIRPIPLNRIF 335
V+AELLLGQP+FPGE+ +DQLVEIIKVLGTPTREEI MN NY++ +FPQI+ P +++F
Sbjct: 262 VLAELLLGQPLFPGENSVDQLVEIIKVLGTPTREEIRCMNPNYTDFRFPQIKAHPWHKVF 321
Query: 336 -KKETQETIDLLYHIMKYDPNIRYSALQCMFNSTYFTDIVSNTGSDSNLSLIDSLPL--L 392
K+ E IDL +++Y P++R +AL+ + + N + N L + PL L
Sbjct: 322 HKRMPPEAIDLASRLLQYSPSLRCTALEACAHPFF------NELREPNARLPNGRPLPPL 375
Query: 393 HFEESELQGLSSNDIYRL 410
+ EL G S I RL
Sbjct: 376 FNFKQELSGASPELINRL 393
>At1g09840 [G] KOG0658 Glycogen synthase kinase-3
Length = 421
Score = 347 bits (889), Expect = 2e-95
Identities = 177/343 (51%), Positives = 240/343 (69%), Gaps = 6/343 (1%)
Query: 70 RTVVKGHSNPEESVVISCGTPEIVGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKNREL 129
RT ++G N + +S + +VG GSFG+VF+ K +ETGE V IKKVLQD+R+KNREL
Sbjct: 67 RTTLRGR-NGQSRQTVSYISEHVVGTGSFGMVFQAKCRETGEVVAIKKVLQDKRYKNREL 125
Query: 130 EIMKLISHPNLIDLKYYFLEQSD-QELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIK 188
+IM+++ HPN + LK+ F ++D +E+YLNL+++++P ++ + + + +Q M +K
Sbjct: 126 QIMQMLDHPNAVALKHSFFSRTDNEEVYLNLVLEFVPETVNRVARSYSRTNQLMPLIYVK 185
Query: 189 IYMFQLFKSLNYLHQVVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYIC 248
+Y +Q+ ++L Y+H +CHRDIKPQN+LV+P T LKICD GSAK L EPNVSYIC
Sbjct: 186 LYTYQICRALAYIHNSFGLCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNVSYIC 245
Query: 249 SRYYRAPELIFGATNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTR 308
SRYYRAPELIFGA+ YTT IDIWS GCVMAELLLGQP+FPGES +DQLVEIIKVLGTPTR
Sbjct: 246 SRYYRAPELIFGASEYTTAIDIWSTGCVMAELLLGQPLFPGESGVDQLVEIIKVLGTPTR 305
Query: 309 EEICSMNENYSEHKFPQIRPIPLNRIFKKE-TQETIDLLYHIMKYDPNIRYSALQCMFNS 367
EEI MN NY+E KFPQI+P P +++F+K E +DLL +Y PN+R +AL+ +
Sbjct: 306 EEIKCMNPNYTEFKFPQIKPHPWHKVFQKRLPPEAVDLLCRFFQYSPNLRCTALEACIHP 365
Query: 368 TYFTDIVSNTGSDSNLSLIDSLPLLHFEESELQGLSSNDIYRL 410
+ NT + L PL +F+ EL G+ + RL
Sbjct: 366 LFDELRDPNTRLPNGRPL---PPLFNFKPQELSGIPPEIVNRL 405
>At5g14640 [G] KOG0658 Glycogen synthase kinase-3
Length = 408
Score = 346 bits (887), Expect = 4e-95
Identities = 179/332 (53%), Positives = 236/332 (70%), Gaps = 9/332 (2%)
Query: 75 GHSNPEESVVISCGTPEIVGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKNRELEIMKL 134
G N + IS IVG GSFG+VF+ K ETGE V IKKVLQD+R+KNREL+ M+L
Sbjct: 62 GGKNGQPKQTISYMAERIVGQGSFGIVFQAKCLETGETVAIKKVLQDKRYKNRELQTMRL 121
Query: 135 ISHPNLIDLKYYFLEQSDQ-ELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQ 193
+ HPN++ LK+ F +++ ELYLNL+++Y+P ++Y+ K + +Q M +K+Y +Q
Sbjct: 122 LDHPNVVSLKHCFFSTTEKDELYLNLVLEYVPETVYRVSKHYSRANQRMPIIYVKLYTYQ 181
Query: 194 LFKSLNYLHQVVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYR 253
+ ++L Y+H V VCHRDIKPQN+LV+P T +K+CD GSAK L EPN+SYICSRYYR
Sbjct: 182 ICRALAYIHGGVGVCHRDIKPQNLLVNPHTHQVKLCDFGSAKVLVKGEPNISYICSRYYR 241
Query: 254 APELIFGATNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICS 313
APELIFGAT YTT IDIWSAGCV+AELLLGQP+FPGES +DQLVEIIKVLGTPTREEI
Sbjct: 242 APELIFGATEYTTTIDIWSAGCVLAELLLGQPLFPGESGVDQLVEIIKVLGTPTREEIKC 301
Query: 314 MNENYSEHKFPQIRPIPLNRIFKKET-QETIDLLYHIMKYDPNIRYSALQCMFNSTYFTD 372
MN NY+E KFPQI+ P ++IF K T E +DL+ +++Y PN+R +A +F +
Sbjct: 302 MNPNYTEFKFPQIKAHPWHKIFHKRTPPEAVDLVSRLLQYSPNLRSTA---AIVHPFFDE 358
Query: 373 IVS-NTGSDSNLSLIDSLPLLHFEESELQGLS 403
+ NT + +L PL +F+ EL+G S
Sbjct: 359 LRDPNTRLPNGRAL---PPLFNFKPQELKGAS 387
>At3g61160 [G] KOG0658 Glycogen synthase kinase-3
Length = 431
Score = 345 bits (886), Expect = 5e-95
Identities = 173/342 (50%), Positives = 241/342 (69%), Gaps = 5/342 (1%)
Query: 71 TVVKGHSNPEESVVISCGTPEIVGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKNRELE 130
T K N ++ IS ++G GSFGVVF+ K ET E V IKKVLQD+R+KNREL+
Sbjct: 86 TTKKKGLNDQKDKTISYRAEHVIGTGSFGVVFQAKCLETEEKVAIKKVLQDKRYKNRELQ 145
Query: 131 IMKLISHPNLIDLKYYFLEQSDQ-ELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKI 189
IM+++ HPN+++LK+ F +++ ELYLNL+++Y+P ++Y+ + + ++Q M I++
Sbjct: 146 IMRMLDHPNVVELKHSFFSTTEKDELYLNLVLEYVPETIYRASRSYTKMNQHMPLIYIQL 205
Query: 190 YMFQLFKSLNYLHQVVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICS 249
Y +Q+ +++NYLHQVV VCHRDIKPQN+LV+ T +KICD GSAK L P EPN+SYICS
Sbjct: 206 YTYQICRAMNYLHQVVGVCHRDIKPQNLLVNNVTHEVKICDFGSAKMLIPGEPNISYICS 265
Query: 250 RYYRAPELIFGATNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTRE 309
RYYRAPELIFGAT YT+ ID+WS GCVMAEL LG P+FPGE+ +DQLVEIIK+LGTP RE
Sbjct: 266 RYYRAPELIFGATEYTSAIDMWSVGCVMAELFLGHPLFPGETSVDQLVEIIKILGTPARE 325
Query: 310 EICSMNENYSEHKFPQIRPIPLNRIFKKE-TQETIDLLYHIMKYDPNIRYSALQCMFNST 368
EI +MN Y++ KFPQI+ P ++IF+++ + E +DL +++Y PN+R +AL+ +
Sbjct: 326 EIKNMNPRYNDFKFPQIKAQPWHKIFRRQVSPEAMDLASRLLQYSPNLRCTALEACAH-P 384
Query: 369 YFTDIVSNTGSDSNLSLIDSLPLLHFEESELQGLSSNDIYRL 410
+F D+ S N + PL F EL G S +RL
Sbjct: 385 FFDDLRDPRASLPNGRALP--PLFDFTAQELAGASVELRHRL 424
>At1g57870 [G] KOG0658 Glycogen synthase kinase-3
Length = 420
Score = 345 bits (885), Expect = 7e-95
Identities = 174/338 (51%), Positives = 238/338 (69%), Gaps = 11/338 (3%)
Query: 78 NPEESVVISCGTPEIVGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKNRELEIMKLISH 137
N + +S +VG GSFG+VF+ K +ETGE V IKKVLQD+R+KNREL+IM+++ H
Sbjct: 73 NGQSRQTVSYIAEHVVGTGSFGMVFQAKCRETGEVVAIKKVLQDKRYKNRELQIMQMLDH 132
Query: 138 PNLIDLKYYFLEQSD-QELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFK 196
PN++ LK+ F +++ +E+YLNL+++++P ++ + + + ++Q M +K+Y +Q+ +
Sbjct: 133 PNVVCLKHSFYSRTENEEVYLNLVLEFVPETVNRTARSYSRMNQLMPLIYVKLYTYQICR 192
Query: 197 SLNYLHQVVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPE 256
L YLH +CHRDIKPQN+LV+P T LKICD GSAK L EPN+SYICSRYYRAPE
Sbjct: 193 GLAYLHNCCGLCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYICSRYYRAPE 252
Query: 257 LIFGATNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNE 316
LIFGAT YTT IDIWS GCVMAELLLGQP+FPGES +DQLVEIIKVLGTPTREEI MN
Sbjct: 253 LIFGATEYTTAIDIWSTGCVMAELLLGQPLFPGESGVDQLVEIIKVLGTPTREEIKCMNP 312
Query: 317 NYSEHKFPQIRPIPLNRIFKKE-TQETIDLLYHIMKYDPNIRYSALQCMFNSTYFTDIVS 375
NY+E KFPQI+P P +++F+K E +DLL +Y PN+R +A++ + +F ++
Sbjct: 313 NYTEFKFPQIKPHPWHKVFQKRLPPEAVDLLCRFFQYSPNLRCTAVEACIH-PFFDEL-- 369
Query: 376 NTGSDSNLSLIDSL---PLLHFEESELQGLSSNDIYRL 410
D N L + PL +F+ EL G+ + RL
Sbjct: 370 ---RDPNARLPNGRPLPPLFNFKPQELSGIPPETVDRL 404
>Hs22051130 [G] KOG0658 Glycogen synthase kinase-3
Length = 483
Score = 343 bits (880), Expect = 3e-94
Identities = 181/346 (52%), Positives = 239/346 (68%), Gaps = 9/346 (2%)
Query: 57 VKIVPDEDEVITRRTVVKGHSNPEESVVISCGTPEIVGNGSFGVVFRTKVKETGEDVVIK 116
VK+ D +V T V PE S ++ +++GNGSFGVV++ ++ ET E V IK
Sbjct: 91 VKLGRDSGKVTT--VVATLGQGPERSQEVAYTDIKVIGNGSFGVVYQARLAETRELVAIK 148
Query: 117 KVLQDRRFKNRELEIMKLISHPNLIDLKYYFLEQSDQ--ELYLNLIVDYMPMSLYQRLKE 174
KVLQD+RFKNREL+IM+ + H N++ L+Y+F ++ ELYLNL+++Y+P ++Y+ +
Sbjct: 149 KVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGEKKDELYLNLVLEYVPETVYRVARH 208
Query: 175 FISLHQPMDRYEIKIYMFQLFKSLNYLHQVVNVCHRDIKPQNILVDPDTLLLKICDLGSA 234
F + +K+YM+QLF+SL Y+H VCHRDIKPQN+LVDPDT +LK+CD GSA
Sbjct: 209 FTKAKLTIPILYVKVYMYQLFRSLAYIHSQ-GVCHRDIKPQNLLVDPDTAVLKLCDFGSA 267
Query: 235 KQLKPNEPNVSYICSRYYRAPELIFGATNYTTKIDIWSAGCVMAELLLGQPIFPGESKID 294
KQL EPNVSYICSRYYRAPELIFGAT+YT+ ID+WSAGCV+AELLLGQPIFPG+S +D
Sbjct: 268 KQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVD 327
Query: 295 QLVEIIKVLGTPTREEICSMNENYSEHKFPQIRPIPLNRIFKKET-QETIDLLYHIMKYD 353
QLVEIIKVLGTPTRE+I MN NY+E KFPQI+ P ++FK T E I L +++Y
Sbjct: 328 QLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWTKVFKSRTPPEAIALCSSLLEYT 387
Query: 354 PNIRYSALQCMFNSTYFTDIVSNTGSDSNLSLIDSLPLLHFEESEL 399
P+ R S L+ +S + T +N L PL +F EL
Sbjct: 388 PSSRLSPLEACAHSFFDELRCLGTQLPNNRPL---PPLFNFSAGEL 430
>Hs11995474 [G] KOG0658 Glycogen synthase kinase-3
Length = 483
Score = 343 bits (880), Expect = 3e-94
Identities = 181/346 (52%), Positives = 239/346 (68%), Gaps = 9/346 (2%)
Query: 57 VKIVPDEDEVITRRTVVKGHSNPEESVVISCGTPEIVGNGSFGVVFRTKVKETGEDVVIK 116
VK+ D +V T V PE S ++ +++GNGSFGVV++ ++ ET E V IK
Sbjct: 91 VKLGRDSGKVTT--VVATLGQGPERSQEVAYTDIKVIGNGSFGVVYQARLAETRELVAIK 148
Query: 117 KVLQDRRFKNRELEIMKLISHPNLIDLKYYFLEQSDQ--ELYLNLIVDYMPMSLYQRLKE 174
KVLQD+RFKNREL+IM+ + H N++ L+Y+F ++ ELYLNL+++Y+P ++Y+ +
Sbjct: 149 KVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGEKKDELYLNLVLEYVPETVYRVARH 208
Query: 175 FISLHQPMDRYEIKIYMFQLFKSLNYLHQVVNVCHRDIKPQNILVDPDTLLLKICDLGSA 234
F + +K+YM+QLF+SL Y+H VCHRDIKPQN+LVDPDT +LK+CD GSA
Sbjct: 209 FTKAKLTIPILYVKVYMYQLFRSLAYIHSQ-GVCHRDIKPQNLLVDPDTAVLKLCDFGSA 267
Query: 235 KQLKPNEPNVSYICSRYYRAPELIFGATNYTTKIDIWSAGCVMAELLLGQPIFPGESKID 294
KQL EPNVSYICSRYYRAPELIFGAT+YT+ ID+WSAGCV+AELLLGQPIFPG+S +D
Sbjct: 268 KQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVD 327
Query: 295 QLVEIIKVLGTPTREEICSMNENYSEHKFPQIRPIPLNRIFKKET-QETIDLLYHIMKYD 353
QLVEIIKVLGTPTRE+I MN NY+E KFPQI+ P ++FK T E I L +++Y
Sbjct: 328 QLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWTKVFKSRTPPEAIALCSSLLEYT 387
Query: 354 PNIRYSALQCMFNSTYFTDIVSNTGSDSNLSLIDSLPLLHFEESEL 399
P+ R S L+ +S + T +N L PL +F EL
Sbjct: 388 PSSRLSPLEACAHSFFDELRCLGTQLPNNRPL---PPLFNFSAGEL 430
>CE21401 [G] KOG0658 Glycogen synthase kinase-3
Length = 362
Score = 343 bits (880), Expect = 3e-94
Identities = 167/281 (59%), Positives = 216/281 (76%), Gaps = 4/281 (1%)
Query: 80 EESVVISCGTPEIVGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKNRELEIMKLISHPN 139
++ V IS +++GNGSFGVVF K+ T E V IKKVLQD+RFKNREL+IM+ ++HPN
Sbjct: 29 DQQVEISYYDQKVIGNGSFGVVFLAKLSTTNEMVAIKKVLQDKRFKNRELQIMRKLNHPN 88
Query: 140 LIDLKYYFLEQSDQ--ELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKS 197
++ LKY+F ++ ELYLNLI++Y+P ++Y+ + + Q + +K+YM+QL +S
Sbjct: 89 IVKLKYFFYSSGEKKDELYLNLILEYVPETVYRVARHYSKQRQQIPMIYVKLYMYQLLRS 148
Query: 198 LNYLHQVVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPEL 257
L Y+H + +CHRDIKPQN+L+DP++ +LK+CD GSAK L NEPNVSYICSRYYRAPEL
Sbjct: 149 LAYIHSI-GICHRDIKPQNLLIDPESGVLKLCDFGSAKYLVRNEPNVSYICSRYYRAPEL 207
Query: 258 IFGATNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNEN 317
IFGATNYT ID+WSAG VMAELLLGQPIFPG+S +DQLVEIIKVLGTPTRE+I SMN N
Sbjct: 208 IFGATNYTNSIDVWSAGTVMAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIQSMNPN 267
Query: 318 YSEHKFPQIRPIPLNRIFKKET-QETIDLLYHIMKYDPNIR 357
Y E KFPQI+ P N++F+ T E IDL+ I++Y P R
Sbjct: 268 YKEFKFPQIKAHPWNKVFRVHTPAEAIDLISKIIEYTPTSR 308
>7290342 [G] KOG0658 Glycogen synthase kinase-3
Length = 1008
Score = 342 bits (877), Expect = 6e-94
Identities = 171/318 (53%), Positives = 236/318 (73%), Gaps = 6/318 (1%)
Query: 85 ISCGTPEIVGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKNRELEIMKLISHPNLIDLK 144
+S +++GNGSFGVVF+ K+ +TGE V IKKVLQDRRFKNREL+IM+ + H N++ L
Sbjct: 546 VSYTDTKVIGNGSFGVVFQAKLCDTGELVAIKKVLQDRRFKNRELQIMRKLEHCNIVKLL 605
Query: 145 YYFLEQSDQ--ELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLH 202
Y+F ++ E++LNL+++Y+P ++Y+ +++ Q + I++YM+QLF+SL Y+H
Sbjct: 606 YFFYSSGEKRDEVFLNLVLEYIPETVYKVARQYAKTKQTIPINFIRLYMYQLFRSLAYIH 665
Query: 203 QVVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGAT 262
+ +CHRDIKPQN+L+DP+T +LK+CD GSAKQL EPNVSYICSRYYRAPELIFGA
Sbjct: 666 SL-GICHRDIKPQNLLLDPETAVLKLCDFGSAKQLLHGEPNVSYICSRYYRAPELIFGAI 724
Query: 263 NYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENYSEHK 322
NYTTKID+WSAGCV+AELLLGQPIFPG+S +DQLVE+IKVLGTPTRE+I MN NY+E K
Sbjct: 725 NYTTKIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEVIKVLGTPTREQIREMNPNYTEFK 784
Query: 323 FPQIRPIPLNRIFKKET-QETIDLLYHIMKYDPNIRYSALQCMFNSTYFTDIVSNTGSDS 381
FPQI+ P ++F+ T E I+L+ +++Y P+ R + L+ + F D + G+ +
Sbjct: 785 FPQIKSHPWQKVFRIRTPTEAINLVSLLLEYTPSARITPLKACAHP--FFDELRMEGNHT 842
Query: 382 NLSLIDSLPLLHFEESEL 399
+ D PL +F E EL
Sbjct: 843 LPNGRDMPPLFNFTEHEL 860
>HsM4504163 [G] KOG0658 Glycogen synthase kinase-3
Length = 420
Score = 341 bits (874), Expect = 1e-93
Identities = 166/316 (52%), Positives = 228/316 (71%), Gaps = 4/316 (1%)
Query: 57 VKIVPDEDEVITRRTVVKGHSNPEESVVISCGTPEIVGNGSFGVVFRTKVKETGEDVVIK 116
+K+ D+D V P+ +S +++GNGSFGVV++ K+ ++GE V IK
Sbjct: 26 MKVSRDKDGSKVTTVVATPGQGPDRPQEVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIK 85
Query: 117 KVLQDRRFKNRELEIMKLISHPNLIDLKYYFLEQSDQ--ELYLNLIVDYMPMSLYQRLKE 174
KVLQD+RFKNREL+IM+ + H N++ L+Y+F ++ E+YLNL++DY+P ++Y+ +
Sbjct: 86 KVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARH 145
Query: 175 FISLHQPMDRYEIKIYMFQLFKSLNYLHQVVNVCHRDIKPQNILVDPDTLLLKICDLGSA 234
+ Q + +K+YM+QLF+SL Y+H +CHRDIKPQN+L+DPDT +LK+CD GSA
Sbjct: 146 YSRAKQTLPVIYVKLYMYQLFRSLAYIHSF-GICHRDIKPQNLLLDPDTAVLKLCDFGSA 204
Query: 235 KQLKPNEPNVSYICSRYYRAPELIFGATNYTTKIDIWSAGCVMAELLLGQPIFPGESKID 294
KQL EPNVSYICSRYYRAPELIFGAT+YT+ ID+WSAGCV+AELLLGQPIFPG+S +D
Sbjct: 205 KQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVD 264
Query: 295 QLVEIIKVLGTPTREEICSMNENYSEHKFPQIRPIPLNRIFKKET-QETIDLLYHIMKYD 353
QLVEIIKVLGTPTRE+I MN NY+E KFPQI+ P ++F+ T E I L +++Y
Sbjct: 265 QLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWTKVFRPRTPPEAIALCSRLLEYT 324
Query: 354 PNIRYSALQCMFNSTY 369
P R + L+ +S +
Sbjct: 325 PTARLTPLEACAHSFF 340
>Hs21361340 [G] KOG0658 Glycogen synthase kinase-3
Length = 433
Score = 333 bits (855), Expect = 2e-91
Identities = 176/362 (48%), Positives = 242/362 (66%), Gaps = 26/362 (7%)
Query: 57 VKIVPDEDEVITRRTVVKGHSNPEESVVISCGTPEIVGNGSFGVVFRTKVKETGEDVVIK 116
+K+ D+D V P+ +S +++GNGSFGVV++ K+ ++GE V IK
Sbjct: 26 MKVSRDKDGSKVTTVVATPGQGPDRPQEVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIK 85
Query: 117 KVLQDRRFKNRELEIMKLISHPNLIDLKYYFLEQSDQ--ELYLNLIVDYMPMSLYQRLKE 174
KVLQD+RFKNREL+IM+ + H N++ L+Y+F ++ E+YLNL++DY+P ++Y+ +
Sbjct: 86 KVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARH 145
Query: 175 FISLHQPMDRYEIKIYMFQLFKSLNYLHQVVNVCHRDIKPQNILVDPDTLLLKICDLGSA 234
+ Q + +K+YM+QLF+SL Y+H +CHRDIKPQN+L+DPDT +LK+CD GSA
Sbjct: 146 YSRAKQTLPVIYVKLYMYQLFRSLAYIHSF-GICHRDIKPQNLLLDPDTAVLKLCDFGSA 204
Query: 235 KQLKPNEPNVSYICSRYYRAPELIFGATNYTTKIDIWSAGCVMAELLLGQPIFPGESKID 294
KQL EPNVSYICSRYYRAPELIFGAT+YT+ ID+WSAGCV+AELLLGQPIFPG+S +D
Sbjct: 205 KQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVD 264
Query: 295 QLVEIIKVLGTPTREEICSMNENYSEHKFPQIRPIPLN-------------RIFKKET-Q 340
QLVEIIKVLGTPTRE+I MN NY+E KFPQI+ P R+F+ T
Sbjct: 265 QLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWTKDSSGTGHFTSGVRVFRPRTPP 324
Query: 341 ETIDLLYHIMKYDPNIRYSALQCMFNSTYFTDIVSNTGSDSNLSL---IDSLPLLHFEES 397
E I L +++Y P R + L+ +S +F ++ D N+ L D+ L +F
Sbjct: 325 EAIALCSRLLEYTPTARLTPLEACAHS-FFDEL-----RDPNVKLPNGRDTPALFNFTTQ 378
Query: 398 EL 399
EL
Sbjct: 379 EL 380
>SPAC1687.15 [G] KOG0658 Glycogen synthase kinase-3
Length = 387
Score = 326 bits (835), Expect = 4e-89
Identities = 162/316 (51%), Positives = 224/316 (70%), Gaps = 9/316 (2%)
Query: 52 SHGNDVKIVPDEDEVITRRTVVKGHSNPEESVVISCGTPEIVGNGSFGVVFRTKVKETGE 111
+HG + + P I + T G + E +S + ++VG+GSFGVV + + E+
Sbjct: 2 NHGTKIPVDPFR---IIKETARDGSTG--EVKQLSYTSSKVVGSGSFGVVMQVHLIESDS 56
Query: 112 DVVIKKVLQDRRFKNRELEIMKLISHPNLIDLKYYFLEQSDQ--ELYLNLIVDYMPMSLY 169
IK+VLQD+RFKNREL+IM+++ HPN++DL Y+ D E+YLNL++++MP ++Y
Sbjct: 57 KAAIKRVLQDKRFKNRELQIMRIMKHPNIVDLIAYYYTTGDNSDEVYLNLVLEFMPETIY 116
Query: 170 QRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVVNVCHRDIKPQNILVDPDTLLLKIC 229
+ + + M E+K+Y++QL +SL Y+H +CHRDIKPQN+L+DP+ +LK+C
Sbjct: 117 RASRLYTRQKLSMPMLEVKLYIYQLLRSLAYIH-ASGICHRDIKPQNLLLDPENGILKLC 175
Query: 230 DLGSAKQLKPNEPNVSYICSRYYRAPELIFGATNYTTKIDIWSAGCVMAELLLGQPIFPG 289
D GSAK L EPNVSYICSRYYRAPELIFGAT+YT IDIWS GCVMAEL+LG P+FPG
Sbjct: 176 DFGSAKILVAGEPNVSYICSRYYRAPELIFGATDYTHAIDIWSTGCVMAELMLGHPLFPG 235
Query: 290 ESKIDQLVEIIKVLGTPTREEICSMNENYSEHKFPQIRPIPLNRIFKKETQ-ETIDLLYH 348
ES IDQLVEIIK+LGTP+RE+I +MN NY EH+FPQIRP PL+R+F + + +DLL
Sbjct: 236 ESGIDQLVEIIKILGTPSREQIKTMNPNYMEHRFPQIRPQPLSRVFSRSVPLDALDLLSK 295
Query: 349 IMKYDPNIRYSALQCM 364
+++Y P R +A + M
Sbjct: 296 MLQYTPTDRLTAAEAM 311
>SPBC8D2.01 [G] KOG0658 Glycogen synthase kinase-3
Length = 381
Score = 298 bits (762), Expect = 1e-80
Identities = 150/305 (49%), Positives = 210/305 (68%), Gaps = 6/305 (1%)
Query: 63 EDEVITRRTVVKGHSNPEESVVISCGTPEIVGNGSFGVVFRTKVKETGEDVVIKKVLQDR 122
+D + + V G + E IS ++G+GSFGVV + K+ T + +K+VLQD+
Sbjct: 3 DDSHLETKVVTDGTTG--EKKTISYEPCRVLGSGSFGVVIQAKLVGTPGFIAVKRVLQDK 60
Query: 123 RFKNRELEIMKLISHPNLIDLKYYFLEQ--SDQELYLNLIVDYMPMSLYQRLKEFISLHQ 180
R+KNREL+IM+ ISHPN+I L +F S E +L L+++YMP +++ ++ + +
Sbjct: 61 RYKNRELQIMRAISHPNIIKLIAFFHTHNPSKDETHLCLLLEYMPETVFDDMRWYTRRRK 120
Query: 181 PMDRYEIKIYMFQLFKSLNYLHQVVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPN 240
+ IK+Y FQLF++L YLH VCHRDIKPQN+LVD T +LK+CD GSAK L P+
Sbjct: 121 SIPNLSIKLYAFQLFRALAYLHST-GVCHRDIKPQNLLVDYKTGILKLCDFGSAKVLVPS 179
Query: 241 EPNVSYICSRYYRAPELIFGATNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEII 300
EPNVSYICSRYYRAPEL+FGAT+YTTKID+WSA CV+AEL +G+P+FPG+S ++QLVEII
Sbjct: 180 EPNVSYICSRYYRAPELVFGATHYTTKIDVWSAACVIAELFIGRPLFPGDSSVEQLVEII 239
Query: 301 KVLGTPTREEICSMNENYSEHKFPQIRPIPLNRIFKKE-TQETIDLLYHIMKYDPNIRYS 359
+VLGTP+ EI MN NY H P +RP L + T+ +DLL+ ++ Y P+ R S
Sbjct: 240 RVLGTPSYHEISVMNPNYVNHSLPNVRPHTLESVMPHNCTKNAMDLLHKMLTYVPSKRIS 299
Query: 360 ALQCM 364
A++ +
Sbjct: 300 AIEVL 304
>SPBPI064 [G] KOG0658 Glycogen synthase kinase-3
Length = 350
Score = 261 bits (668), Expect = 1e-69
Identities = 128/242 (52%), Positives = 174/242 (71%), Gaps = 4/242 (1%)
Query: 126 NRELEIMKLISHPNLIDLKYYFLEQ--SDQELYLNLIVDYMPMSLYQRLKEFISLHQPMD 183
NREL+IM+ ISHPN+I L +F S E +L L+++YMP +++ ++ + + +
Sbjct: 33 NRELQIMRAISHPNIIKLIAFFHTHNPSKDETHLCLLLEYMPETVFDDMRWYTRRRKSIP 92
Query: 184 RYEIKIYMFQLFKSLNYLHQVVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPN 243
IK+Y FQLF++L YLH VCHRDIKPQN+LVD T +LK+CD GSAK L P+EPN
Sbjct: 93 NLSIKLYAFQLFRALAYLHST-GVCHRDIKPQNLLVDYKTGILKLCDFGSAKVLVPSEPN 151
Query: 244 VSYICSRYYRAPELIFGATNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVL 303
VSYICSRYYRAPEL+FGAT+YTTKID+WSA CV+AEL +G+P+FPG+S ++QLVEII+VL
Sbjct: 152 VSYICSRYYRAPELVFGATHYTTKIDVWSAACVIAELFIGRPLFPGDSSVEQLVEIIRVL 211
Query: 304 GTPTREEICSMNENYSEHKFPQIRPIPLNRIFKKE-TQETIDLLYHIMKYDPNIRYSALQ 362
GTP+ EI MN NY H P +RP L + T+ +DLL+ ++ Y P+ R SA++
Sbjct: 212 GTPSYHEISVMNPNYVNHSLPNVRPHTLESVMPHNCTKNAMDLLHKMLTYVPSKRISAIE 271
Query: 363 CM 364
+
Sbjct: 272 VL 273
>CE08727 [G] KOG0658 Glycogen synthase kinase-3
Length = 367
Score = 249 bits (636), Expect = 5e-66
Identities = 130/298 (43%), Positives = 186/298 (61%), Gaps = 5/298 (1%)
Query: 77 SNPEESVVISCGTPEIVGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKNRELEIMKLIS 136
S + V I +++G GSFG V++ ++E E + IKK+ D RFK+REL IM +
Sbjct: 27 SKLDREVEIQFTNLQLIGTGSFGAVYKAVLRENDEPIAIKKIKVDDRFKSRELTIMHEMD 86
Query: 137 HPNLIDLKYYFLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFK 196
HPN+I L YY++ Q QE LN ++++MP L ++F + M Y IK+YMFQL +
Sbjct: 87 HPNIIRLLYYYVMQ--QENCLNFVMEFMPKDLAYVHRQFAHNDKQMPAYSIKLYMFQLLR 144
Query: 197 SLNYLHQVVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPE 256
+ +LH + N+ HRDIKP+N+LVD +LKICD GSAK+L+ NEPN++YICSRYYRAPE
Sbjct: 145 GIGFLH-LHNIVHRDIKPKNLLVDESNGILKICDFGSAKRLEKNEPNITYICSRYYRAPE 203
Query: 257 LIFGATNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNE 316
LIFG+ NY T ID WS G V+ ELL PIF +S +D L IK GTP++E++ N
Sbjct: 204 LIFGSKNYDTSIDTWSVGTVVGELLHNSPIFLADSAVDILALQIKAFGTPSKEDMAKWNY 263
Query: 317 NYSEHKFPQIRPIPLNR-IFKKETQETIDLLYHIMKYDPNIRYSALQCMFNSTYFTDI 373
Y + I + + + I +K + T++LL +MK DP +R + + YF D+
Sbjct: 264 EYVHIPYDTITGVGIQKFIGRKLSLSTLELLNSLMKMDPKLRIKPYEAL-TLPYFDDL 320
>YNL307c [G] KOG0658 Glycogen synthase kinase-3
Length = 375
Score = 218 bits (554), Expect = 2e-56
Identities = 124/323 (38%), Positives = 186/323 (57%), Gaps = 19/323 (5%)
Query: 93 VGNGSFGVVFRTKVKETGED----VVIKKVLQDRRFKNRELEIMKLISHPNLIDLKYYF- 147
+G G+FG V + + + ++ IKKV +K+REL+I+++ HPN++ L+Y+F
Sbjct: 41 IGRGAFGTVVQAYLTQDKKNWLGPFAIKKVPAHTEYKSRELQILRIADHPNIVKLQYFFT 100
Query: 148 -LEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVVN 206
L D ++Y +L ++ +P +L + +++ M I++Y +Q+ + + YLH +
Sbjct: 101 HLSPQDNKVYQHLAMECLPETLQIEINRYVTNKLEMPLKHIRLYTYQIARGMLYLHGL-G 159
Query: 207 VCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGATNYTT 266
VCHRDIKP N+LVDP+T +LKICD GSAK+L+ N+P++SYICSR+YRAPELI G T YTT
Sbjct: 160 VCHRDIKPSNVLVDPETGVLKICDFGSAKKLEHNQPSISYICSRFYRAPELIIGCTQYTT 219
Query: 267 KIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENY-----SEH 321
+IDIW GCVM E+L+G+ IF G+ + QL EI K+LG P + I N Y S+
Sbjct: 220 QIDIWGLGCVMGEMLIGKAIFQGQEPLLQLREIAKLLGPPDKRFIFFSNPAYDGPLFSKP 279
Query: 322 KFPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSALQCM----FNSTYFTDIVSNT 377
F + F + IDLL I+ Y+P R S + + FN D
Sbjct: 280 LFSGSSQQRFEKYFGHSGPDGIDLLMKILVYEPQQRLSPRRILAHQFFNELRNDDTFLPR 339
Query: 378 GSDSNLSLIDSLPLLHFEESELQ 400
G + L + L F + ELQ
Sbjct: 340 GFTEPIKLPN---LFDFNDFELQ 359
>YOL128c [G] KOG0658 Glycogen synthase kinase-3
Length = 375
Score = 181 bits (459), Expect = 2e-45
Identities = 112/331 (33%), Positives = 181/331 (53%), Gaps = 35/331 (10%)
Query: 93 VGNGSFGVVFRTKVKETGED----VVIKKVLQDRRFKNRELEIMKLISHPNLIDLKYYF- 147
+G+GSFG V ++ + + IK+V++ + ++ ELEI++ I HPNL+ L+++F
Sbjct: 47 IGHGSFGTVTQSILSSNSIEWLGPYAIKRVVKSPKVQSLELEILQNIRHPNLVTLEFFFE 106
Query: 148 ---LEQSDQELYL-NLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQ 203
+ LY N +++Y+P +L + E+ M IK+Y FQ+ ++L LH
Sbjct: 107 SHCTTKDGGHLYQKNFVMEYIPQTLSSEIHEYFDNGSKMPTKHIKLYTFQILRALLTLHS 166
Query: 204 VVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGATN 263
+ ++CH D+KP NIL+ P + + K+CD GSA++L N +Y CSR+YRAPEL+ + +
Sbjct: 167 M-SICHGDLKPSNILIIPSSGIAKVCDFGSAQRLDDNTELKTYFCSRFYRAPELLLNSKD 225
Query: 264 YTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICS---MNENYSE 320
YTT+IDIWS GC++ E++ GQP+F G+S QL EI K+LG + I + + ++ ++
Sbjct: 226 YTTQIDIWSLGCIIGEMIKGQPLFKGDSANSQLEEIAKLLGRFPKSSIKNSQELQDSLND 285
Query: 321 HKFPQ-IRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSALQCMF--------NSTYFT 371
KF + + P F ++ L ++ YD R A Q M N TYF
Sbjct: 286 QKFKKFMHWFPSIEFF------DVEFLLKVLTYDATERCDARQLMAHEFFDALRNETYFL 339
Query: 372 DIVSNTGSDSNLSLIDSLPLLHFEESELQGL 402
GS + L D L +F SE + L
Sbjct: 340 P----RGSSMPVHLPD---LFNFSASEKRAL 363
>ECU07g1270 [G] KOG0658 Glycogen synthase kinase-3
Length = 334
Score = 178 bits (451), Expect = 2e-44
Identities = 95/216 (43%), Positives = 143/216 (65%), Gaps = 11/216 (5%)
Query: 91 EIVGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKNRELEIMKLISHPNLIDLKYYF-LE 149
E++G GSFGVV + + + +K+V QDRR+ NREL I+ + HPN++ L YF +
Sbjct: 60 EMIGRGSFGVVVKI-MDDRHNFFALKRVYQDRRYHNRELGILMEVDHPNIVRLVSYFHTD 118
Query: 150 QSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVVNVCH 209
++ YLN+I D++ M+L +E+I ++ ++ EI+ Q+ + L YLH+ N+CH
Sbjct: 119 KTSSGAYLNIITDFVGMNL----EEYIKANRGVETEEIRSVYRQILEGLRYLHEK-NICH 173
Query: 210 RDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGATNYTTKID 269
RD+KP NIL+D + L+ KICDLGSAK +K E N++YICSR+YRAPE + Y KID
Sbjct: 174 RDMKPSNILIDTNGLV-KICDLGSAKVIKSGERNITYICSRFYRAPENLLDYKEYDFKID 232
Query: 270 IWSAGCVMAELLLGQPIFPGE---SKIDQLVEIIKV 302
IWS GCV+AE PIF G+ S +++++EI++V
Sbjct: 233 IWSVGCVIAEFRHPGPIFKGDTSGSTLNRILEIVRV 268
>7297578 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 822
Score = 174 bits (441), Expect = 2e-43
Identities = 100/284 (35%), Positives = 167/284 (58%), Gaps = 26/284 (9%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQ-----DRRFKNRELEIMKLISHPNLIDLKYYF 147
+G+G++G V + K+TGE V IK++ + + RE++ +K +SHPN++ LK
Sbjct: 10 LGDGTYGTVVLGQRKDTGEKVAIKRMKRKYYSWEEAMNLREVKSLKKLSHPNIVKLKEVI 69
Query: 148 LEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVVNV 207
E L + +YM +LYQ +K+ H P E+K +FQ+ L ++H+
Sbjct: 70 RENDT----LYFVFEYMKENLYQMIKDR-DTHLPEP--ELKSILFQVLTGLAFMHRH-GF 121
Query: 208 CHRDIKPQNILVD-PDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGATNYTT 266
HRD+KP+N+L PD L+KI D G A++++ P Y+ +R+YRAPE++ +TNY +
Sbjct: 122 FHRDLKPENLLCSGPD--LIKIADFGLAREIRSRPPFTDYVSTRWYRAPEVLLHSTNYGS 179
Query: 267 KIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREE------ICSMNENYSE 320
ID+W+ GC+MAEL +P+FPG S++DQL +I VLGTP +++ + SM
Sbjct: 180 TIDLWAMGCIMAELYTFRPLFPGSSEVDQLFKICSVLGTPDKDDWPDGYRLASM----IH 235
Query: 321 HKFPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSALQCM 364
++P +PL+ + + +Q +DLL ++ YDP+ R +A Q +
Sbjct: 236 FRYPDCIKVPLSSVVSRCSQNGLDLLEDMLAYDPDKRPTAQQSL 279
>7298004 [G] KOG0658 Glycogen synthase kinase-3
Length = 392
Score = 173 bits (438), Expect = 5e-43
Identities = 109/323 (33%), Positives = 174/323 (53%), Gaps = 18/323 (5%)
Query: 57 VKIVPDEDEVITRRTVVKGHSNPEESVVISCGTPEIVGNGSFGVVFRTKVKETGEDVVIK 116
V ++ ++ VI+ V + S P ++ +++G+GSFG V++ V E+ E V +K
Sbjct: 17 VPLIIPKNSVISTYAVGRLCSEP---ALVRIEVKDLIGSGSFGRVYQAHVNESEEIVAVK 73
Query: 117 KVLQDRRFKNRELEIM-KLISHPNLIDLKYYFLEQSDQEL------YLNLIVDYMPMSLY 169
+ L + + E EIM +L H N++ L + S L Y+ L+++YMPM+L
Sbjct: 74 QTLYNPKLSQGEAEIMGQLKDHNNIVRL----IMHSSVSLGFPSVDYVLLVMEYMPMTLL 129
Query: 170 QRLKEFISLHQPMDRY-EIKIYMFQLFKSLNYLHQVVNVCHRDIKPQNILVDPDTLLLKI 228
+ +++ QP +R ++I +Q+F+ L YLH ++ + HRD+KP+N+L+D ++LK+
Sbjct: 130 DYINYHLTVLQPAERLINVRILSYQMFRGLGYLH-LLGISHRDVKPENLLIDNQKMVLKL 188
Query: 229 CDLGSAKQLKPNEPNVSYICSRYYRAPELIFGATNYTTKIDIWSAGCVMAELLLGQPIFP 288
D GSAK L P EP++SYICSR YRAPEL G Y+ +DIWSAGCV+AELL G P+F
Sbjct: 189 SDFGSAKLLVPQEPSISYICSRLYRAPELFAGYELYSCAVDIWSAGCVLAELLKGYPLFS 248
Query: 289 G-ESKIDQLVEIIKVLGTPTREEICSMNENYSEHKFPQIRPIPLNRIFKKET-QETIDLL 346
+ QL I+ +LGT E + P+ N + Q+ LL
Sbjct: 249 SHKHDRKQLRLIVNMLGTDGLERAPEILSKCGNSLHPRTTRPSWNYLLNTAVPQDLCGLL 308
Query: 347 YHIMKYDPNIRYSALQCMFNSTY 369
Y+ R S + + +Y
Sbjct: 309 NSCFIYEAAARISPMMACSHGSY 331
>Hs4502743 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 346
Score = 169 bits (429), Expect = 5e-42
Identities = 103/295 (34%), Positives = 163/295 (54%), Gaps = 26/295 (8%)
Query: 91 EIVGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN---------RELEIMKLISHPNLI 141
+ +G G F V++ + K T + V IKK+ R + RE+++++ +SHPN+I
Sbjct: 16 DFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNII 75
Query: 142 DLKYYFLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYL 201
L F +S+ ++L+ D+M L +K+ + P IK YM + L YL
Sbjct: 76 GLLDAFGHKSN----ISLVFDFMETDLEVIIKDNSLVLTPS---HIKAYMLMTLQGLEYL 128
Query: 202 HQVVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQL-KPNEPNVSYICSRYYRAPELIFG 260
HQ + HRD+KP N+L+D + +L K+ D G AK PN + +R+YRAPEL+FG
Sbjct: 129 HQHW-ILHRDLKPNNLLLDENGVL-KLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFG 186
Query: 261 ATNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTRE---EICSMNEN 317
A Y +D+W+ GC++AELLL P PG+S +DQL I + LGTPT E ++CS+ +
Sbjct: 187 ARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDY 246
Query: 318 YSEHKFPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSALQCMFNSTYFTD 372
+ FP IPL+ IF + +DL+ + ++P R +A Q + YF++
Sbjct: 247 VTFKSFP---GIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQAL-KMKYFSN 297
>At1g76540 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 313
Score = 169 bits (429), Expect = 5e-42
Identities = 100/294 (34%), Positives = 164/294 (55%), Gaps = 15/294 (5%)
Query: 91 EIVGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN------RELEIMKLISHP----NL 140
E VG G++G V+R + K TG+ V +KK + RE+ I+++++ L
Sbjct: 18 EKVGEGTYGKVYRAREKATGKIVALKKTRLHEDEEGVPSTTLREISILRMLARDPHVVRL 77
Query: 141 IDLKYYFLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNY 200
+D+K ++ LYL + +YM + + ++ F S + + IK M+QL K + +
Sbjct: 78 MDVKQGLSKEGKTVLYL--VFEYMDTDVKKFIRSFRSTGKNIPTQTIKSLMYQLCKGMAF 135
Query: 201 LHQVVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLK-PNEPNVSYICSRYYRAPELIF 259
H + HRD+KP N+L+DP T+ LKI DLG A+ P + I + +YRAPE++
Sbjct: 136 CHGH-GILHRDLKPHNLLMDPKTMRLKIADLGLARAFTLPMKKYTHEILTLWYRAPEVLL 194
Query: 260 GATNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENYS 319
GAT+Y+T +D+WS GC+ AEL+ Q IF G+S++ QL+ I K+ GTP E ++ +
Sbjct: 195 GATHYSTAVDMWSVGCIFAELVTNQAIFQGDSELQQLLHIFKLFGTPNEEMWPGVSTLKN 254
Query: 320 EHKFPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSALQCMFNSTYFTDI 373
H++PQ +P L+ + +DLL +++Y+P R SA M YF D+
Sbjct: 255 WHEYPQWKPSTLSSAVPNLDEAGVDLLSKMLQYEPAKRISAKMAM-EHPYFDDL 307
>At1g20930 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 315
Score = 166 bits (421), Expect = 5e-41
Identities = 99/294 (33%), Positives = 165/294 (55%), Gaps = 15/294 (5%)
Query: 91 EIVGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN------RELEIMKLISHP----NL 140
E VG G++G V+R + K TG V +KK + RE+ I+++++ L
Sbjct: 20 EKVGEGTYGKVYRAREKATGMIVALKKTRLHEDEEGVPPTTLREISILRMLARDPHIVRL 79
Query: 141 IDLKYYFLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNY 200
+D+K ++ LYL + +Y+ L + ++ F Q + + +K M+QL K + +
Sbjct: 80 MDVKQGINKEGKTVLYL--VFEYVDTDLKKFIRSFRQAGQNIPQNTVKCLMYQLCKGMAF 137
Query: 201 LHQVVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLK-PNEPNVSYICSRYYRAPELIF 259
H V HRD+KP N+L+D T+ LKI DLG A+ P + I + +YRAPE++
Sbjct: 138 CHGH-GVLHRDLKPHNLLMDRKTMTLKIADLGLARAFTLPMKKYTHEILTLWYRAPEVLL 196
Query: 260 GATNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENYS 319
GAT+Y+T +D+WS GC+ AEL+ Q IF G+S++ QL+ I ++LGTP E +++
Sbjct: 197 GATHYSTGVDMWSVGCIFAELVTKQAIFAGDSELQQLLRIFRLLGTPNEEVWPGVSKLKD 256
Query: 320 EHKFPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSALQCMFNSTYFTDI 373
H++PQ +P+ L+ + +DLL +++Y+P R SA + M YF D+
Sbjct: 257 WHEYPQWKPLSLSTAVPNLDEAGLDLLSKMLEYEPAKRISAKKAM-EHPYFDDL 309
>At1g73670 [T] KOG0660 Mitogen-activated protein kinase
Length = 576
Score = 165 bits (418), Expect = 1e-40
Identities = 112/335 (33%), Positives = 178/335 (52%), Gaps = 27/335 (8%)
Query: 91 EIVGNGSFGVVFRTKVKETGEDVVIKKV------LQDRRFKNRELEIMKLISHPNLIDLK 144
E+VG GS+GVV TGE V IKK+ + D RE+++++L+ HP+++++K
Sbjct: 94 EVVGKGSYGVVGSAIDTHTGERVAIKKINDVFDHISDATRILREIKLLRLLLHPDVVEIK 153
Query: 145 YYFLEQSDQELY-LNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQ 203
+ L S +E + ++ + M L+Q +K L ++ +++QL + L Y+H
Sbjct: 154 HIMLPPSRREFRDVYVVFELMESDLHQVIKANDDLTPEHHQF----FLYQLLRGLKYVH- 208
Query: 204 VVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNV----SYICSRYYRAPELIF 259
NV HRD+KP+NIL + D L KICD G A+ + P Y+ +R+YRAPEL
Sbjct: 209 AANVFHRDLKPKNILANADCKL-KICDFGLARVSFNDAPTAIFWTDYVATRWYRAPELCG 267
Query: 260 GA-TNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENY 318
+ YT IDIWS GC+ AE+LLG+P+FPG++ + QL + LGTP E I + +
Sbjct: 268 SFFSKYTPAIDIWSVGCIFAEMLLGKPLFPGKNVVHQLDIMTDFLGTPPPEAISKIRNDK 327
Query: 319 SEHKFPQIR---PIPLNRIFKKETQETIDLLYHIMKYDPNIRYSALQCMFNSTYFTDIVS 375
+ +R P+P ++ F K + LL ++ +DP R SA + + + YF + S
Sbjct: 328 ARRYLGNMRKKQPVPFSKKFPKADPSALRLLERLIAFDPKDRPSAEEALAD-PYFNGLSS 386
Query: 376 NTGSDSNLSLIDSLPLLHFEESELQGLSSNDIYRL 410
S + L F E E + L+ +DI L
Sbjct: 387 KVREPST----QPISKLEF-EFERKKLTKDDIREL 416
>At1g18150 [T] KOG0660 Mitogen-activated protein kinase
Length = 589
Score = 164 bits (416), Expect = 2e-40
Identities = 108/324 (33%), Positives = 172/324 (52%), Gaps = 24/324 (7%)
Query: 91 EIVGNGSFGVVFRTKVKETGEDVVIKKV------LQDRRFKNRELEIMKLISHPNLIDLK 144
E+VG GS+GVV TGE V IKK+ + D RE+++++L+ HP+++++K
Sbjct: 108 EVVGKGSYGVVASAVDSHTGERVAIKKINDVFEHVSDATRILREIKLLRLLRHPDVVEIK 167
Query: 145 YYFLEQSDQELY-LNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQ 203
+ L S +E + ++ + M L+Q +K + + + +++QL + L Y+H
Sbjct: 168 HIMLPPSRREFRDIYVVFELMESDLHQVIKA----NDDLTPEHYQFFLYQLLRGLKYVH- 222
Query: 204 VVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNV----SYICSRYYRAPELIF 259
NV HRD+KP+NIL + D L KICD G A+ + P Y+ +R+YRAPEL
Sbjct: 223 AANVFHRDLKPKNILANADCKL-KICDFGLARVSFNDAPTAIFWTDYVATRWYRAPELCG 281
Query: 260 GA-TNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENY 318
+ YT IDIWS GC+ AE+LLG+P+FPG++ + QL + LGTP E I +
Sbjct: 282 SFFSKYTPAIDIWSVGCIFAEMLLGKPLFPGKNVVHQLDLMTDFLGTPPPESISRIRNEK 341
Query: 319 SEHKFPQIR---PIPLNRIFKKETQETIDLLYHIMKYDPNIRYSALQCMFNSTYFTDIVS 375
+ +R P+P + F K + LL ++ +DP R SA + + YF+ + S
Sbjct: 342 ARRYLSSMRKKQPVPFSHKFPKADPLALRLLERLLAFDPKDRASAEDALAD-PYFSGL-S 399
Query: 376 NTGSDSNLSLIDSLPLLHFEESEL 399
N+ + I L FE +L
Sbjct: 400 NSEREPTTQPISKLE-FDFERKKL 422
>Hs4505569 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 493
Score = 164 bits (414), Expect = 3e-40
Identities = 93/276 (33%), Positives = 160/276 (57%), Gaps = 19/276 (6%)
Query: 92 IVGNGSFGVVFRTKVKETGEDVVIKKVLQD------RRFKNRELEIMKLISHPNLIDLKY 145
+VG GS+G+V + + K+TG V IKK L+ ++ RE++++K + H NL++L
Sbjct: 9 LVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHENLVNL-- 66
Query: 146 YFLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVV 205
LE ++ L+ +++ ++ L+ F + +D ++ Y+FQ+ + + H
Sbjct: 67 --LEVCKKKKRWYLVFEFVDHTILDDLELFPN---GLDYQVVQKYLFQIINGIGFCHSH- 120
Query: 206 NVCHRDIKPQNILVDPDTLLLKICDLGSAKQLK-PNEPNVSYICSRYYRAPELIFGATNY 264
N+ HRDIKP+NILV ++ K+CD G A+ L P E Y+ +R+YRAPEL+ G Y
Sbjct: 121 NIIHRDIKPENILVSQSGVV-KLCDFGFARTLAAPGEVYTDYVATRWYRAPELLVGDVKY 179
Query: 265 TTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGT--PTREEICSMNENYSEHK 322
+D+W+ GC++ E+ +G+P+FPG+S IDQL I+ LG P +E+ + N ++ +
Sbjct: 180 GKAVDVWAIGCLVTEMFMGEPLFPGDSDIDQLYHIMMCLGNLIPRHQELFNKNPVFAGVR 239
Query: 323 FPQIRP-IPLNRIFKKETQETIDLLYHIMKYDPNIR 357
P+I+ PL R + K ++ IDL + DP+ R
Sbjct: 240 LPEIKEREPLERRYPKLSEVVIDLAKKCLHIDPDKR 275
>Hs4507281 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 1030
Score = 163 bits (413), Expect = 4e-40
Identities = 102/292 (34%), Positives = 167/292 (56%), Gaps = 22/292 (7%)
Query: 92 IVGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN------RELEIMKLISHPNLIDLKY 145
+VG G++GVV + + KET E V IKK + REL++++ + N+++LK
Sbjct: 18 VVGEGAYGVVLKCRHKETHEIVAIKKFKDSEENEEVKETTLRELKMLRTLKQENIVELKE 77
Query: 146 YFLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVV 205
F + L L+ +Y+ ++ + L+E + P ++K Y++QL K++++ H+
Sbjct: 78 AFRRRGK----LYLVFEYVEKNMLELLEEMPNGVPPE---KVKSYIYQLIKAIHWCHKN- 129
Query: 206 NVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKP--NEPNVSYICSRYYRAPELIFGATN 263
++ HRDIKP+N+L+ + +L K+CD G A+ L N Y+ +R+YR+PEL+ GA
Sbjct: 130 DIVHRDIKPENLLISHNDVL-KLCDFGFARNLSEGNNANYTEYVATRWYRSPELLLGAP- 187
Query: 264 YTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENYSEH-- 321
Y +D+WS GC++ EL GQP+FPGES+IDQL I KVLG E++ N H
Sbjct: 188 YGKSVDMWSVGCILGELSDGQPLFPGESEIDQLFTIQKVLGPLPSEQMKLFYSNPRFHGL 247
Query: 322 KFPQI-RPIPLNRIFKKETQET-IDLLYHIMKYDPNIRYSALQCMFNSTYFT 371
+FP + P L R + +DL+ +++K DP RY QC+ + T+ T
Sbjct: 248 RFPAVNHPQSLERRYLGILNSVLLDLMKNLLKLDPADRYLTEQCLNHPTFQT 299
>Hs4758652 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 358
Score = 162 bits (411), Expect = 7e-40
Identities = 97/291 (33%), Positives = 166/291 (56%), Gaps = 20/291 (6%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQD------RRFKNRELEIMKLISHPNLIDLKYY 146
+G GS+GVVF+ + ++TG+ V IKK L+ ++ RE+ ++K + HPNL++L
Sbjct: 11 IGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQLKHPNLVNL--- 67
Query: 147 FLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVVN 206
LE ++ L+L+ +Y ++ L + + + + +K +Q +++N+ H+ N
Sbjct: 68 -LEVFRRKRRLHLVFEYCDHTVLHELDRY---QRGVPEHLVKSITWQTLQAVNFCHKH-N 122
Query: 207 VCHRDIKPQNILVDPDTLLLKICDLGSAKQLK-PNEPNVSYICSRYYRAPELIFGATNYT 265
HRD+KP+NIL+ +++ K+CD G A+ L P++ Y+ +R+YR+PEL+ G T Y
Sbjct: 123 CIHRDVKPENILITKHSVI-KLCDFGFARLLTGPSDYYTDYVATRWYRSPELLVGDTQYG 181
Query: 266 TKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLG--TPTREEICSMNENYSEHKF 323
+D+W+ GCV AELL G P++PG+S +DQL I K LG P +++ S N+ +S K
Sbjct: 182 PPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLGDLIPRHQQVFSTNQYFSGVKI 241
Query: 324 PQIRPI-PLNRIFKKETQETIDLLYHIMKYDPNIRYSALQCMFNSTYFTDI 373
P + PL F + + LL + DP R + Q + + YF +I
Sbjct: 242 PDPEDMEPLELKFPNISYPALGLLKGCLHMDPTERLTCEQ-LLHHPYFENI 291
>At4g19110 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 256
Score = 162 bits (411), Expect = 7e-40
Identities = 86/240 (35%), Positives = 149/240 (61%), Gaps = 12/240 (5%)
Query: 127 RELEIMKLISHPNLIDLKYYFLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYE 186
RE++ ++ ++HPN++ LK E L + +YM +LYQ +K+ L D
Sbjct: 15 REVKSLRRMNHPNIVKLKEVIREND----ILYFVFEYMECNLYQLMKDRQKLFAEAD--- 67
Query: 187 IKIYMFQLFKSLNYLHQVVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSY 246
IK + FQ+F+ L+Y+HQ HRD+KP+N+LV D ++KI D G A+++ + P Y
Sbjct: 68 IKNWCFQVFQGLSYMHQR-GYFHRDLKPENLLVSKD--IIKIADFGLAREVNSSPPFTEY 124
Query: 247 ICSRYYRAPELIFGATNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTP 306
+ +R+YRAPE++ + YT+K+D+W+ G +MAELL +PIFPG S+ D++ +I V+GTP
Sbjct: 125 VSTRWYRAPEVLLQSYVYTSKVDMWAMGAIMAELLSLRPIFPGASEADEIYKICSVIGTP 184
Query: 307 TREE-ICSMN-ENYSEHKFPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSALQCM 364
T E + +N N ++FPQ+ +PL+ + +++ I+L+ + +DP+ R +A + +
Sbjct: 185 TEETWLEGLNLANTINYQFPQLPGVPLSSLMPSASEDAINLIERLCSWDPSSRPTAAEVL 244
>At3g48750 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 294
Score = 162 bits (411), Expect = 7e-40
Identities = 94/293 (32%), Positives = 165/293 (56%), Gaps = 20/293 (6%)
Query: 91 EIVGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN------RELEIMKLISHPNLIDLK 144
E +G G++GVV++ + K T E + +KK+ ++ + RE+ ++K + H N++ K
Sbjct: 8 EKIGEGTYGVVYKARDKVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQHSNIV--K 65
Query: 145 YYFLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQV 204
Y + S++ LYL + +Y+ + L + + + D + IK Y++Q+ + + Y H
Sbjct: 66 YDDVVHSEKRLYL--VFEYLDLDLKKHMDSTPDFSK--DLHMIKTYLYQILRGIAYCHSH 121
Query: 205 VNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLK-PNEPNVSYICSRYYRAPELIFGATN 263
V HRD+KPQN+L+D T LK+ D G A+ P + + +YRAPE++ G+ +
Sbjct: 122 -RVLHRDLKPQNLLIDRRTNSLKLADFGLARAFGIPVRTFTHEVVTLWYRAPEILLGSHH 180
Query: 264 YTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTP---TREEICSMNENYSE 320
Y+T +DIWS GC+ AE++ +P+FPG+S+IDQL +I +++GTP T + S+ + S
Sbjct: 181 YSTPVDIWSVGCIFAEMISQKPLFPGDSEIDQLFKIFRIMGTPYEDTWRGVTSLPDYKS- 239
Query: 321 HKFPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSALQCMFNSTYFTDI 373
FP+ +P L + +DLL ++ DP R +A + YF D+
Sbjct: 240 -AFPKWKPTDLETFVPNLDPDGVDLLSKMLLMDPTKRINA-RAALEHEYFKDL 290
>SPAC24B11.06c [T] KOG0660 Mitogen-activated protein kinase
Length = 349
Score = 161 bits (407), Expect = 2e-39
Identities = 92/281 (32%), Positives = 152/281 (53%), Gaps = 21/281 (7%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQD------RRFKNRELEIMKLISHPNLIDLKYY 146
+G G+FG+V K + TG +V +KK+++ + REL+++K + H N+I L
Sbjct: 26 IGMGAFGLVCSAKDQLTGMNVAVKKIMKPFSTPVLAKRTYRELKLLKHLRHENIISLSDI 85
Query: 147 FLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVVN 206
F+ + + + + + L++ L +P++ I+ +++Q+ + L ++H
Sbjct: 86 FISPFED---IYFVTELLGTDLHRLLTS-----RPLETQFIQYFLYQILRGLKFVHSA-G 136
Query: 207 VCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGATNYTT 266
V HRD+KP NIL++ + LKICD G A+ P Y+ +RYYRAPE++ Y
Sbjct: 137 VIHRDLKPSNILIN-ENCDLKICDFGLARIQDPQM--TGYVSTRYYRAPEIMLTWQKYNV 193
Query: 267 KIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTR---EEICSMNENYSEHKF 323
++DIWSAGC+ AE++ G+P+FPG ++Q I ++LGTP E ICS N
Sbjct: 194 EVDIWSAGCIFAEMIEGKPLFPGRDHVNQFSIITELLGTPPMEVIETICSKNTLRFVQSL 253
Query: 324 PQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSALQCM 364
PQ +P FK + IDLL ++ +DP R SA +
Sbjct: 254 PQKEKVPFAEKFKNADPDAIDLLEKMLVFDPRKRISAADAL 294
>Hs7705551 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 632
Score = 160 bits (405), Expect = 3e-39
Identities = 93/283 (32%), Positives = 163/283 (56%), Gaps = 24/283 (8%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQ-----DRRFKNRELEIMKLISHPNLIDLKYYF 147
+G+G++G V + E+GE + IKK+ + + RE++ +K ++H N++ LK
Sbjct: 10 LGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNQREVKSLKKLNHANVVKLKEVI 69
Query: 148 LEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVVNV 207
E +L I +YM +LYQ +KE L I+ M+Q+ + L ++H++
Sbjct: 70 REND----HLYFIFEYMKENLYQLIKERNKL---FPESAIRNIMYQILQGLAFIHKL-GF 121
Query: 208 CHRDIKPQNIL-VDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGATNYTT 266
HRD+KP+N+L + P+ L+KI D G A++++ P Y+ +R+YRAPE++ +TNY++
Sbjct: 122 FHRDLKPENLLCMGPE--LVKIADFGLAREIRSKPPYTDYVSTRWYRAPEVLLRSTNYSS 179
Query: 267 KIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENYS-----EH 321
ID+W+ GC+MAE+ +P+FPG S+ID + +I +VLGTP + + E Y
Sbjct: 180 PIDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTD---WPEGYQLSSAMNF 236
Query: 322 KFPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSALQCM 364
++PQ P L + + E + LL ++++DP R +A Q +
Sbjct: 237 RWPQCVPNNLKTLIPNASSEAVQLLRDMLQWDPKKRPTASQAL 279
>At2g42880 [T] KOG0660 Mitogen-activated protein kinase
Length = 594
Score = 160 bits (404), Expect = 4e-39
Identities = 95/289 (32%), Positives = 162/289 (55%), Gaps = 21/289 (7%)
Query: 91 EIVGNGSFGVVFRTKVKETGEDVVIKKV------LQDRRFKNRELEIMKLISHPNLIDLK 144
E++G GS+GVV TGE V IKK+ + D RE+++++L+ HP+++++K
Sbjct: 17 EVIGKGSYGVVCSAIDTLTGEKVAIKKIHDIFEHISDAARILREIKLLRLLRHPDIVEIK 76
Query: 145 YYFLEQSDQELY-LNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQ 203
+ L S +E + ++ + M L+Q +K + + R + +++QL ++L Y+H
Sbjct: 77 HIMLPPSRREFKDIYVVFELMESDLHQVIKA----NDDLTREHYQFFLYQLLRALKYIH- 131
Query: 204 VVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNV----SYICSRYYRAPELIF 259
NV HRD+KP+NIL + + L KICD G A+ + P Y+ +R+YRAPEL
Sbjct: 132 TANVYHRDLKPKNILANANCKL-KICDFGLARVAFNDTPTTIFWTDYVATRWYRAPELCG 190
Query: 260 GA-TNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENY 318
+ YT IDIWS GC+ AE+L+G+P+FPG++ + QL + +LGTP+ + I +
Sbjct: 191 SFYSKYTPAIDIWSIGCIFAEVLMGKPLFPGKNVVHQLDLMTDLLGTPSLDTISRVRNEK 250
Query: 319 SEHKFPQIR---PIPLNRIFKKETQETIDLLYHIMKYDPNIRYSALQCM 364
+ +R PIP + F ++ LL ++ +DP R +A + +
Sbjct: 251 ARRYLTSMRKKPPIPFAQKFPNADPLSLKLLERLLAFDPKDRPTAEEAL 299
>At2g38620 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 311
Score = 160 bits (404), Expect = 4e-39
Identities = 101/306 (33%), Positives = 168/306 (54%), Gaps = 30/306 (9%)
Query: 91 EIVGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN------RELEIMKLISHP------ 138
E VG G++G V++ K TG+ V +KK + + RE+ +++++S
Sbjct: 8 EKVGEGTYGKVYKAMEKTTGKLVALKKTRLEMDEEGIPPTALREISLLQMLSQSIYIVRL 67
Query: 139 ----NLIDLKYYFLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQ------PMDRYEIK 188
++I K + S + L L+ +Y+ L K+FI H+ P++ ++
Sbjct: 68 LCVEHVIQSKDSTVSHSPKS-NLYLVFEYLDTDL----KKFIDSHRKGSNPRPLEASLVQ 122
Query: 189 IYMFQLFKSLNYLHQVVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLK-PNEPNVSYI 247
+MFQLFK + + H V HRD+KPQN+L+D D +LKI DLG ++ P + I
Sbjct: 123 RFMFQLFKGVAHCHSH-GVLHRDLKPQNLLLDKDKGILKIADLGLSRAFTVPLKAYTHEI 181
Query: 248 CSRYYRAPELIFGATNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPT 307
+ +YRAPE++ G+T+Y+T +DIWS GC+ AE++ Q +FPG+S+ QL+ I ++LGTPT
Sbjct: 182 VTLWYRAPEVLLGSTHYSTAVDIWSVGCIFAEMIRRQALFPGDSEFQQLLHIFRLLGTPT 241
Query: 308 REEICSMNENYSEHKFPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSALQCMFNS 367
++ + H +P+ P L+R + E IDLL ++KY+P R SA + +
Sbjct: 242 EQQWPGVMALRDWHVYPKWEPQDLSRAVPSLSPEGIDLLTQMLKYNPAERISA-KAALDH 300
Query: 368 TYFTDI 373
YF +
Sbjct: 301 PYFDSL 306
>7300773 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 302
Score = 160 bits (404), Expect = 4e-39
Identities = 98/283 (34%), Positives = 165/283 (57%), Gaps = 23/283 (8%)
Query: 91 EIVGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN------RELEIMKLISHPNLIDLK 144
E +G G G VF+ + ++V IKKV +F N RE++ ++L ++D+
Sbjct: 13 EKIGEGVHGCVFKAIDLQRNKEVAIKKVALKNKFGNIALNTLREIKTLQLCKSEYILDII 72
Query: 145 YYFLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQV 204
+ + + L+L+++Y P +LY RLK ++ P+ R +++ + Q+FK + YLH+
Sbjct: 73 DIYPDLTG----LSLVLEYQPDTLYNRLKSEVN---PLSRQQVRKFAHQMFKGIAYLHEA 125
Query: 205 VNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSY---ICSRYYRAPELIFGA 261
+ HRDIKP N+L+ DT +LKI D G A+ P + + Y + +R+YRAPE++FG+
Sbjct: 126 -GLMHRDIKPANLLIS-DTDMLKIADFGLARLYFPEDESRLYSPQVSTRWYRAPEILFGS 183
Query: 262 TNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTRE---EICSMNENY 318
Y T +D+W+AGCV+AE+L G P+F G + I+QL II+ LG+P E+ S+ +Y
Sbjct: 184 QKYGTGVDMWAAGCVVAEMLRGVPLFAGTTDIEQLAIIIRTLGSPRLNQWPELTSL-PDY 242
Query: 319 SEHKFPQIRPIPLNRIFKKETQET-IDLLYHIMKYDPNIRYSA 360
S+ +FP I + +F T I+L+ +++ Y+P R A
Sbjct: 243 SKIRFPNSVGIHWDNLFPSCTHAVEINLVSNLVVYNPKNRLKA 285
>CE12408 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 527
Score = 159 bits (403), Expect = 6e-39
Identities = 92/286 (32%), Positives = 166/286 (57%), Gaps = 30/286 (10%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQ-----DRRFKNRELEIMKLISHPNLIDLKYYF 147
+G+G+FG V K +TG+ V IK++ + + RE++ +K ++HPN+I L+
Sbjct: 51 LGDGTFGEVMLAKKIDTGDRVAIKRMKKKFYSWEEAMSLREVKSLKKLNHPNIIKLREVI 110
Query: 148 LEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRY----EIKIYMFQLFKSLNYLHQ 203
E L + ++M +LY+ +K+ DRY I+ ++Q+ + L ++H+
Sbjct: 111 REND----ILYFVFEFMQENLYELMKD-------RDRYFPESVIRNIIYQVLQGLAFMHK 159
Query: 204 VVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGATN 263
HRD+KP+NI+ + T L+KI D G A++++ P Y+ +R+YRAPE++ +T+
Sbjct: 160 N-GFFHRDMKPENIMCN-GTELVKIADFGLAREIRSKPPYTDYVSTRWYRAPEILLRSTS 217
Query: 264 YTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENYS---- 319
Y + ID+W+ GC+MAEL + +P+FPG S++DQL +II +LGTP ++E E Y
Sbjct: 218 YNSPIDMWALGCIMAELYILRPLFPGTSEMDQLFKIISILGTPNKDE---WPEGYQLASA 274
Query: 320 -EHKFPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSALQCM 364
+F Q+ P+ ++ ++E + L+ +M ++P R +A Q +
Sbjct: 275 MNFRFQQVVATPMEQVVNTISKEGMKLMMDMMLWNPEKRPNANQSL 320
>Hs11496279 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 623
Score = 159 bits (402), Expect = 7e-39
Identities = 95/283 (33%), Positives = 162/283 (56%), Gaps = 24/283 (8%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQ-----DRRFKNRELEIMKLISHPNLIDLKYYF 147
+G+G++G V K E+GE V IK++ + D RE++ +K ++H N+I LK
Sbjct: 10 LGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLNHANVIKLKEVI 69
Query: 148 LEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVVNV 207
E +L I +YM +LYQ +K+ L I+ M+Q+ + L ++H+
Sbjct: 70 REND----HLYFIFEYMKENLYQLMKDRNKL---FPESVIRNIMYQILQGLAFIHKH-GF 121
Query: 208 CHRDIKPQNIL-VDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGATNYTT 266
HRD+KP+N+L + P+ L+KI D G A++L+ P Y+ +R+YRAPE++ ++ Y++
Sbjct: 122 FHRDMKPENLLCMGPE--LVKIADFGLARELRSQPPYTDYVSTRWYRAPEVLLRSSVYSS 179
Query: 267 KIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENYS-----EH 321
ID+W+ G +MAEL + +P+FPG S++D++ +I +VLGTP + + E Y
Sbjct: 180 PIDVWAVGSIMAELYMLRPLFPGTSEVDEIFKICQVLGTPKKSD---WPEGYQLASSMNF 236
Query: 322 KFPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSALQCM 364
+FPQ PI L + + E I L+ ++ +DP R +A Q +
Sbjct: 237 RFPQCVPINLKTLIPNASNEAIQLMTEMLNWDPKKRPTASQAL 279
>At3g18040 [T] KOG0660 Mitogen-activated protein kinase
Length = 613
Score = 159 bits (401), Expect = 9e-39
Identities = 104/335 (31%), Positives = 176/335 (52%), Gaps = 27/335 (8%)
Query: 91 EIVGNGSFGVVFRTKVKETGEDVVIKKV------LQDRRFKNRELEIMKLISHPNLIDLK 144
E++G GS+GVV +GE V IKK+ + D RE+++++L+ HP+++++K
Sbjct: 130 EVIGKGSYGVVASAIDTHSGEKVAIKKINDVFEHVSDATRILREIKLLRLLRHPDIVEIK 189
Query: 145 YYFLEQSDQELY-LNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQ 203
+ L S +E + ++ + M L+Q +K + + + +++QL + L ++H
Sbjct: 190 HVMLPPSRREFRDIYVVFELMESDLHQVIKA----NDDLTPEHYQFFLYQLLRGLKFIH- 244
Query: 204 VVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNV----SYICSRYYRAPELIF 259
NV HRD+KP+NIL + D L KICD G A+ + P+ Y+ +R+YRAPEL
Sbjct: 245 TANVFHRDLKPKNILANSDCKL-KICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELCG 303
Query: 260 GA-TNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENY 318
+ YT IDIWS GC+ AE+L G+P+FPG++ + QL + +LGTP E I +
Sbjct: 304 SFFSKYTPAIDIWSIGCIFAEMLTGKPLFPGKNVVHQLDIMTDLLGTPPPEAIARIRNEK 363
Query: 319 SEHKFPQIR---PIPLNRIFKKETQETIDLLYHIMKYDPNIRYSALQCMFNSTYFTDIVS 375
+ +R P+P F + LL+ ++ +DP R SA + + + YF + +
Sbjct: 364 ARRYLGNMRRKPPVPFTHKFPHVDPLALRLLHRLLAFDPKDRPSAEEALAD-PYFYGLAN 422
Query: 376 NTGSDSNLSLIDSLPLLHFEESELQGLSSNDIYRL 410
S +P L F E E + ++ D+ L
Sbjct: 423 VDREPST----QPIPKLEF-EFERRKITKEDVREL 452
>At3g14720 [T] KOG0660 Mitogen-activated protein kinase
Length = 586
Score = 159 bits (401), Expect = 9e-39
Identities = 94/289 (32%), Positives = 160/289 (54%), Gaps = 21/289 (7%)
Query: 91 EIVGNGSFGVVFRTKVKETGEDVVIKKV------LQDRRFKNRELEIMKLISHPNLIDLK 144
E++G GS+GVV +TGE V IKK+ + D RE+++++L+ HP+++++K
Sbjct: 17 EVIGKGSYGVVCAAIDTQTGEKVAIKKINDVFEHVSDALRILREVKLLRLLRHPDIVEIK 76
Query: 145 YYFLEQSDQELY-LNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQ 203
L S +E + ++ + M L+Q +K + + R + +++Q+ ++L Y+H
Sbjct: 77 SIMLPPSKREFKDIYVVFELMESDLHQVIKA----NDDLTREHHQFFLYQMLRALKYMH- 131
Query: 204 VVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNV----SYICSRYYRAPELIF 259
NV HRD+KP+NIL + + L K+CD G A+ + P Y+ +R+YRAPEL
Sbjct: 132 TANVYHRDLKPKNILANANCKL-KVCDFGLARVSFNDTPTTVFWTDYVATRWYRAPELCG 190
Query: 260 G-ATNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENY 318
+ YT IDIWS GC+ AE+L G+P+FPG+S + QL I +LGTP E I +
Sbjct: 191 SFCSKYTPAIDIWSIGCIFAEVLTGKPLFPGKSVVHQLDLITDLLGTPKSETIAGVRNEK 250
Query: 319 SEHKFPQIRP---IPLNRIFKKETQETIDLLYHIMKYDPNIRYSALQCM 364
+ ++R +P ++ F + LL ++ +DP R +A + +
Sbjct: 251 ARKYLNEMRKKNLVPFSQKFPNADPLALRLLQRLLAFDPKDRPTAAEAL 299
>At5g19010 [T] KOG0660 Mitogen-activated protein kinase
Length = 567
Score = 158 bits (400), Expect = 1e-38
Identities = 96/289 (33%), Positives = 158/289 (54%), Gaps = 21/289 (7%)
Query: 91 EIVGNGSFGVVFRTKVKETGEDVVIKKV------LQDRRFKNRELEIMKLISHPNLIDLK 144
E++G GS+GVV TGE V IKK+ + D RE+++++L+ HP+++++K
Sbjct: 29 EVIGKGSYGVVCSAYDTHTGEKVAIKKINDIFEHVSDATRILREIKLLRLLRHPDIVEIK 88
Query: 145 YYFLEQSDQELY-LNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQ 203
+ L S +E + ++ + M L+Q +K + + + +++QL + L Y+H
Sbjct: 89 HILLPPSRREFRDIYVVFELMESDLHQVIKA----NDDLTPEHYQFFLYQLLRGLKYIH- 143
Query: 204 VVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNV----SYICSRYYRAPELIF 259
NV HRD+KP+NIL + D L KICD G A+ + P Y+ +R+YRAPEL
Sbjct: 144 TANVFHRDLKPKNILANADCKL-KICDFGLARVAFNDTPTAIFWTDYVATRWYRAPELCG 202
Query: 260 GA-TNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENY 318
+ YT IDIWS GC+ AELL G+P+FPG++ + QL + +LGTP+ E I +
Sbjct: 203 SFFSKYTPAIDIWSIGCIFAELLTGKPLFPGKNVVHQLDLMTDMLGTPSAEAIGRVRNEK 262
Query: 319 SEHKFPQIR---PIPLNRIFKKETQETIDLLYHIMKYDPNIRYSALQCM 364
+ +R PIP + F + LL ++ ++P R +A + +
Sbjct: 263 ARRYLSSMRKKKPIPFSHKFPHTDPLALRLLEKMLSFEPKDRPTAEEAL 311
>Hs7662388 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 632
Score = 158 bits (399), Expect = 2e-38
Identities = 95/285 (33%), Positives = 164/285 (57%), Gaps = 28/285 (9%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN-------RELEIMKLISHPNLIDLKY 145
+G+G++G V + E+GE + IKK+ R+F + RE++ +K ++H N++ LK
Sbjct: 10 LGDGTYGSVLLGRSIESGELIAIKKM--KRKFYSWEECMNLREVKSLKKLNHANVVKLKE 67
Query: 146 YFLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVV 205
E +L I +YM +LYQ +KE L I+ M+Q+ + L ++H+
Sbjct: 68 VIREND----HLYFIFEYMKENLYQLIKERNKL---FPESAIRNIMYQILQGLAFIHKH- 119
Query: 206 NVCHRDIKPQNIL-VDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGATNY 264
HRD+KP+N+L + P+ L+KI D G A++++ P Y+ +R+YRAPE++ +TNY
Sbjct: 120 GFFHRDLKPENLLCMGPE--LVKIADFGLAREIRSKPPYTDYVSTRWYRAPEVLLRSTNY 177
Query: 265 TTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENYS----- 319
++ ID+W+ GC+MAE+ +P+FPG S+ID + +I +VLGTP + + E Y
Sbjct: 178 SSPIDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTD---WPEGYQLSSAM 234
Query: 320 EHKFPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSALQCM 364
++PQ P L + + E + LL ++++DP R +A Q +
Sbjct: 235 NFRWPQCVPNNLKTLIPNASSEAVQLLRDMLQWDPKKRPTASQAL 279
>Hs4502709 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 297
Score = 158 bits (399), Expect = 2e-38
Identities = 99/293 (33%), Positives = 165/293 (55%), Gaps = 20/293 (6%)
Query: 91 EIVGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN------RELEIMKLISHPNLIDLK 144
E +G G++GVV++ + K TG+ V +KK+ + + RE+ ++K + HPN++ L+
Sbjct: 8 EKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQ 67
Query: 145 YYFLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQV 204
++ D LYL I +++ M L + L + I Q MD +K Y++Q+ + + + H
Sbjct: 68 DVLMQ--DSRLYL--IFEFLSMDLKKYL-DSIPPGQYMDSSLVKSYLYQILQGIVFCHSR 122
Query: 205 VNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLK-PNEPNVSYICSRYYRAPELIFGATN 263
V HRD+KPQN+L+D D +K+ D G A+ P + + +YR+PE++ G+
Sbjct: 123 -RVLHRDLKPQNLLID-DKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSAR 180
Query: 264 YTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTRE---EICSMNENYSE 320
Y+T +DIWS G + AEL +P+F G+S+IDQL I + LGTP E E+ S+ + +
Sbjct: 181 YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQD--YK 238
Query: 321 HKFPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSALQCMFNSTYFTDI 373
+ FP+ +P L K + +DLL ++ YDP R S + N YF D+
Sbjct: 239 NTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMAL-NHPYFNDL 290
>At3g59790 [T] KOG0660 Mitogen-activated protein kinase
Length = 393
Score = 157 bits (398), Expect = 2e-38
Identities = 89/282 (31%), Positives = 156/282 (54%), Gaps = 17/282 (6%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQ------DRRFKNRELEIMKLISHPNLIDLKYY 146
+G G+ G+V ET E V IKK+ Q + + RE+++++ H N++ ++
Sbjct: 66 IGRGACGIVCSAVDSETNEKVAIKKITQVFDNTIEAKRTLREIKLLRHFDHENIVAIRDV 125
Query: 147 FLE-QSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVV 205
L Q D + ++ + M LY+ LK L + Y +M+Q+ + L Y+H
Sbjct: 126 ILPPQRDSFEDVYIVNELMEFDLYRTLKSDQELTKDHGMY----FMYQILRGLKYIHSA- 180
Query: 206 NVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGATNYT 265
NV HRD+KP N+L+ L KICD G A+ + Y+ +R+YRAPEL+ G+++YT
Sbjct: 181 NVLHRDLKPSNLLLSTQCDL-KICDFGLARATPESNLMTEYVVTRWYRAPELLLGSSDYT 239
Query: 266 TKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENYSEHKFPQ 325
ID+WS GC+ E++ +P+FPG+ +++QL +++++GTP+ EE+ S++E Y++ Q
Sbjct: 240 AAIDVWSVGCIFMEIMNREPLFPGKDQVNQLRLLLELIGTPSEEELGSLSE-YAKRYIRQ 298
Query: 326 IRPIP---LNRIFKKETQETIDLLYHIMKYDPNIRYSALQCM 364
+ +P F IDL+ ++ +DP R S + +
Sbjct: 299 LPTLPRQSFTEKFPNVPPLAIDLVEKMLTFDPKQRISVKEAL 340
>At5g45430 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 530
Score = 157 bits (397), Expect = 3e-38
Identities = 95/297 (31%), Positives = 168/297 (55%), Gaps = 29/297 (9%)
Query: 93 VGNGSFGVVFRTKVKETGE--------DVVIKKVLQ-----DRRFKNRELEIMKLISHPN 139
VG+G+FG V+R K+T E V IK++ + + RE++ + ++HPN
Sbjct: 10 VGDGTFGNVWRAVNKQTNEVGTEVFYVQVAIKRMKKKYFSWEECVNLREVKSLSRMNHPN 69
Query: 140 LIDLKYYFLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLN 199
++ LK E L + +YM +LYQ +K+ D I+ + FQ+F+ L+
Sbjct: 70 IVKLKEVIREND----ILYFVFEYMECNLYQLMKDRPKHFAESD---IRNWCFQVFQGLS 122
Query: 200 YLHQVVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIF 259
Y+HQ HRD+KP+N+LV D ++KI DLG A+++ + P Y+ +R+YRAPE++
Sbjct: 123 YMHQR-GYFHRDLKPENLLVSKD--VIKIADLGLAREIDSSPPYTEYVSTRWYRAPEVLL 179
Query: 260 GATNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREE-ICSMN-EN 317
+ YT+K+D+W+ G +MAELL +P+FPG S+ D++ +I V+G+PT E + +N +
Sbjct: 180 QSYVYTSKVDMWAMGAIMAELLSLRPLFPGASEADEIYKICSVIGSPTEETWLEGLNLAS 239
Query: 318 YSEHKFPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSALQCM----FNSTYF 370
++FPQ + L+ + + + ++L+ + +DP R + + + F S Y+
Sbjct: 240 VINYQFPQFPGVHLSSVMPYASADAVNLIERLCSWDPCNRPTTAEALQHPFFQSCYY 296
>At1g67580 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 752
Score = 157 bits (397), Expect = 3e-38
Identities = 106/357 (29%), Positives = 183/357 (50%), Gaps = 32/357 (8%)
Query: 32 EMDSILPSDDLKQGSLHSKNSHGNDVKIVPDEDEVITRRTVVKGHSNPEESVVISCGTPE 91
E D++ SD ++ + + D D D+ R + S P S+ + G
Sbjct: 344 ERDAV-KSDKMEIDEEEHRRENSVDSLSETDSDDEYVRHETPEPASTPLRSINMLQGCRS 402
Query: 92 I--------VGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN------RELEIMKLISH 137
+ + G++GVV+R K K+TGE V +KKV ++ + RE+ I+ H
Sbjct: 403 VDEFERLNKIDEGTYGVVYRAKDKKTGEIVALKKVKMEKEREGFPLTSLREINILLSFHH 462
Query: 138 PNLIDLKYYFLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKS 197
P+++D+K + S +++ +++YM L ++ ++ Q + E+K M QL +
Sbjct: 463 PSIVDVKEVVVGSSLDSIFM--VMEYMEHDLKALME---TMKQRFSQSEVKCLMLQLLEG 517
Query: 198 LNYLHQVVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQL-KPNEPNVSYICSRYYRAPE 256
+ YLH V HRD+K N+L++ + LKICD G A+Q P +P + + +YRAPE
Sbjct: 518 VKYLHDNW-VLHRDLKTSNLLLN-NRGELKICDFGLARQYGSPLKPYTHLVVTLWYRAPE 575
Query: 257 LIFGATNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTR------EE 310
L+ GA Y+T ID+WS GC+MAELL+ P+F G+++ DQL +I ++LGTP +
Sbjct: 576 LLLGAKQYSTAIDMWSLGCIMAELLMKAPLFNGKTEFDQLDKIFRILGTPNESIWPGFSK 635
Query: 311 ICSMNENYSEHKFPQIR---PIPLNRIFKKETQETIDLLYHIMKYDPNIRYSALQCM 364
+ + N+ +H++ +R P + DLL ++ YDP R + + +
Sbjct: 636 LPGVKVNFVKHQYNLLRKKFPATSFTGAPVLSDAGFDLLNKLLTYDPERRITVNEAL 692
>At1g53510 [T] KOG0660 Mitogen-activated protein kinase
Length = 603
Score = 157 bits (397), Expect = 3e-38
Identities = 92/282 (32%), Positives = 157/282 (55%), Gaps = 21/282 (7%)
Query: 91 EIVGNGSFGVVFRTKVKETGEDVVIKKV------LQDRRFKNRELEIMKLISHPNLIDLK 144
E++G GS+GVV TGE V IKK+ + D RE+++++L+ HP+++++K
Sbjct: 17 EVIGKGSYGVVCAAIDTHTGEKVAIKKINDVFEHISDALRILREVKLLRLLRHPDIVEIK 76
Query: 145 YYFLEQSDQELY-LNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQ 203
L S +E + ++ + M L+Q +K + + R + +++Q+ ++L ++H
Sbjct: 77 SIMLPPSKREFKDIYVVFELMESDLHQVIKA----NDDLTREHHQFFLYQMLRALKFMH- 131
Query: 204 VVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNV----SYICSRYYRAPELIF 259
NV HRD+KP+NIL + + L K+CD G A+ + P Y+ +R+YRAPEL
Sbjct: 132 TANVYHRDLKPKNILANANCKL-KVCDFGLARVAFNDTPTTVFWTDYVATRWYRAPELCG 190
Query: 260 GA-TNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENY 318
+ YT ID+WS GC+ AE+L G+P+FPG+S + QL I +LGTP E I + +
Sbjct: 191 SFFSKYTPAIDVWSIGCIFAEVLTGKPLFPGKSVVHQLELITDLLGTPKSETISGVRNDK 250
Query: 319 SEHKFPQIR---PIPLNRIFKKETQETIDLLYHIMKYDPNIR 357
+ ++R P+ ++ F K + LL ++ +DP R
Sbjct: 251 ARKYLTEMRKKNPVTFSQKFSKADPLALRLLQRLLAFDPKDR 292
>At1g66750 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 348
Score = 156 bits (394), Expect = 6e-38
Identities = 96/294 (32%), Positives = 158/294 (53%), Gaps = 17/294 (5%)
Query: 91 EIVGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN------RELEIMKLISHPNLIDLK 144
+I+G G++GVV++ +TG+ V +KK+ + + RE++++K ++HP++++L
Sbjct: 17 QILGEGTYGVVYKATDTKTGKTVAVKKIRLGNQKEGVNFTALREIKLLKELNHPHIVEL- 75
Query: 145 YYFLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQV 204
++ + L+L+ +YM L +++ P D IK YM K L Y H+
Sbjct: 76 ---IDAFPHDGSLHLVFEYMQTDLEAVIRDRNIFLSPGD---IKSYMLMTLKGLAYCHKK 129
Query: 205 VNVCHRDIKPQNILVDPDTLLLKICDLGSAKQL-KPNEPNVSYICSRYYRAPELIFGATN 263
V HRD+KP N+L+ + LL K+ D G A+ PN + + +YRAPEL+FG+
Sbjct: 130 W-VLHRDMKPNNLLIGENGLL-KLADFGLARLFGSPNRRFTHQVFATWYRAPELLFGSRQ 187
Query: 264 YTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENYSEHKF 323
Y +D+W+AGC+ AELLL +P PG ++IDQL +I + GTP + M +F
Sbjct: 188 YGAGVDVWAAGCIFAELLLRRPFLPGSTEIDQLGKIFQAFGTPVPSQWSDMIYLPDYMEF 247
Query: 324 PQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSALQCMFNSTYFTDIVSNT 377
PL IF + + +DLL + YDP R + Q + + YF+ S T
Sbjct: 248 SYTPAPPLRTIFPMASDDALDLLAKMFIYDPRQRITIQQAL-DHRYFSSSPSPT 300
>At2g18170 [T] KOG0660 Mitogen-activated protein kinase
Length = 368
Score = 155 bits (393), Expect = 8e-38
Identities = 103/290 (35%), Positives = 160/290 (54%), Gaps = 27/290 (9%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKNR--------ELEIMKLISHPNLIDLK 144
+G G++GVV + +ET E V IKK+ F+NR EL++++ + H N+I LK
Sbjct: 38 IGRGAYGVVCSSINRETNERVAIKKI--HNVFENRVDALRTLRELKLLRHVRHENVIALK 95
Query: 145 YYFL---EQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYL 201
L S +++YL + + M L+Q +K SL +Y ++FQL + L YL
Sbjct: 96 DVMLPANRSSFKDVYL--VYELMDTDLHQIIKSSQSLSDDHCKY----FLFQLLRGLKYL 149
Query: 202 HQVVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVS-YICSRYYRAPELIFG 260
H N+ HRD+KP N+LV+ + L KICD G A+ + NE ++ Y+ +R+YRAPEL+
Sbjct: 150 HSA-NILHRDLKPGNLLVNANCDL-KICDFGLARTSQGNEQFMTEYVVTRWYRAPELLLC 207
Query: 261 ATNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENYSE 320
NY T ID+WS GC+ AE+L +PIFPG ++QL II V+G+ +I +N
Sbjct: 208 CDNYGTSIDVWSVGCIFAEILGRKPIFPGTECLNQLKLIINVVGSQQESDI-RFIDNPKA 266
Query: 321 HKF----PQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSALQCMFN 366
+F P R L+ ++ + IDLL ++ +DP R S + +
Sbjct: 267 RRFIKSLPYSRGTHLSNLYPQANPLAIDLLQRMLVFDPTKRISVTDALLH 316
>YLR113w [T] KOG0660 Mitogen-activated protein kinase
Length = 435
Score = 155 bits (392), Expect = 1e-37
Identities = 91/281 (32%), Positives = 152/281 (53%), Gaps = 21/281 (7%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQD------RRFKNRELEIMKLISHPNLIDLKYY 146
VG G+FG+V T + V IKK+++ + REL+++K + H NLI L+
Sbjct: 29 VGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTAVLAKRTYRELKLLKHLRHENLICLQDI 88
Query: 147 FLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVVN 206
FL + + + + L++ L+ +P+++ ++ +++Q+ + L Y+H
Sbjct: 89 FLSPLED---IYFVTELQGTDLHRLLQT-----RPLEKQFVQYFLYQILRGLKYVHSA-G 139
Query: 207 VCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGATNYTT 266
V HRD+KP NIL++ + LKICD G A+ P Y+ +RYYRAPE++ Y
Sbjct: 140 VIHRDLKPSNILIN-ENCDLKICDFGLARIQDPQM--TGYVSTRYYRAPEIMLTWQKYDV 196
Query: 267 KIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTRE---EICSMNENYSEHKF 323
++DIWSAGC+ AE++ G+P+FPG+ + Q I +LG+P ++ ICS N
Sbjct: 197 EVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVINTICSENTLKFVTSL 256
Query: 324 PQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSALQCM 364
P PIP + FK + +DLL ++ +DP R +A +
Sbjct: 257 PHRDPIPFSERFKTVEPDAVDLLEKMLVFDPKKRITAADAL 297
>CE29020 [T] KOG0660 Mitogen-activated protein kinase
Length = 470
Score = 155 bits (391), Expect = 1e-37
Identities = 90/291 (30%), Positives = 159/291 (53%), Gaps = 27/291 (9%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQ-------DRRFKNRELEIMKLISHPNLIDLKY 145
+G G++G+V++ K + E V +KK+ +R + + + HPN+I L
Sbjct: 19 LGKGAYGIVWKAYDKRSRETVALKKIFDAFRNPTDSQRTFREVMFLQEFGKHPNVIKLYN 78
Query: 146 YFLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVV 205
F +D+++YL ++M L+ +K+ L +Y M QLF+++ +LH
Sbjct: 79 IFRADNDRDIYLAF--EFMEADLHNVIKKGSILKDVHKQY----IMCQLFRAIRFLHSG- 131
Query: 206 NVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNE--------PNVS-YICSRYYRAPE 256
NV HRD+KP N+L+D D + K+ D G A+ L E P+++ Y+ +R+YR+PE
Sbjct: 132 NVLHRDLKPSNVLLDADCRV-KLADFGLARSLSSLEDYPEGQKMPDLTEYVATRWYRSPE 190
Query: 257 LIFGATNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNE 316
++ A YT +D+WS GC++AE+L+G+ +FPG S I+Q+ I+ + P+R +I S+
Sbjct: 191 ILLAAKRYTKGVDMWSLGCILAEMLIGRALFPGSSTINQIERIMNTIAKPSRADIASIGS 250
Query: 317 NYSE---HKFPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSALQCM 364
+Y+ K PQ PL+ I + ID++ ++ + P R + QC+
Sbjct: 251 HYAASVLEKMPQRPRKPLDLIITQSQTAAIDMVQRLLIFAPQKRLTVEQCL 301
>Hs4557439 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 305
Score = 154 bits (389), Expect = 2e-37
Identities = 92/279 (32%), Positives = 158/279 (55%), Gaps = 18/279 (6%)
Query: 91 EIVGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN------RELEIMKLISHPNLIDLK 144
E +G G++GVV++ K +ETG+ V +KK+ D + RE+ ++K + HPN++ L
Sbjct: 8 EKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKHPNIVRL- 66
Query: 145 YYFLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQV 204
L+ E L L+ +++ L + + P+ + IK Y+FQL + +++ H
Sbjct: 67 ---LDVVHNERKLYLVFEFLSQDLKKYMDSTPGSELPL--HLIKSYLFQLLQGVSFCHSH 121
Query: 205 VNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLK-PNEPNVSYICSRYYRAPELIFGATN 263
V HRD+KPQN+L++ + +K+ D G A+ P + + +YRAPE++ G+
Sbjct: 122 -RVIHRDLKPQNLLIN-ELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSKF 179
Query: 264 YTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNE--NYSEH 321
YTT +DIWS GC+ AE++ + +FPG+S+IDQL I ++LGTP+ + + + +Y +
Sbjct: 180 YTTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLPDY-KG 238
Query: 322 KFPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSA 360
FP+ L I E DLL +++YDP+ R +A
Sbjct: 239 SFPKWTRKGLEEIVPNLEPEGRDLLMQLLQYDPSQRITA 277
>YDL108w [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 306
Score = 153 bits (387), Expect = 4e-37
Identities = 96/293 (32%), Positives = 165/293 (55%), Gaps = 24/293 (8%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN-------RELEIMKLISHPNLIDLKY 145
VG G++ VV+ TG + IK++ + FK+ RE++ ++ + HPN+I+L
Sbjct: 13 VGEGTYAVVYLGCQHSTGRKIAIKEI-KTSEFKDGLDMSAIREVKYLQEMQHPNVIELID 71
Query: 146 YFLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVV 205
F+ + LNL+++++P L +K+ L P D IK +M + + + H+
Sbjct: 72 IFMAYDN----LNLVLEFLPTDLEVVIKDKSILFTPAD---IKAWMLMTLRGVYHCHRNF 124
Query: 206 NVCHRDIKPQNILVDPDTLLLKICDLGSAKQLK-PNEPNVSYICSRYYRAPELIFGATNY 264
+ HRD+KP N+L PD + K+ D G A+ + P+E S + +R+YRAPEL+FGA +Y
Sbjct: 125 -ILHRDLKPNNLLFSPDGQI-KVADFGLARAIPAPHEILTSNVVTRWYRAPELLFGAKHY 182
Query: 265 TTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENYSEHKFP 324
T+ IDIWS G + AEL+L P PG++ +DQ+ + LGTPT + ++ + +K
Sbjct: 183 TSAIDIWSVGVIFAELMLRIPYLPGQNDVDQMEVTFRALGTPTDRDWPEVSSFMTYNKL- 241
Query: 325 QIRPIP----LNRIFKKETQETIDLLYHIMKYDPNIRYSALQCMFNSTYFTDI 373
QI P P L + F ++ +D + ++ +P R++A+QC+ S YF ++
Sbjct: 242 QIYPPPSRDELRKRFIAASEYALDFMCGMLTMNPQKRWTAVQCL-ESDYFKEL 293
>At3g45640 [T] KOG0660 Mitogen-activated protein kinase
Length = 370
Score = 153 bits (387), Expect = 4e-37
Identities = 87/284 (30%), Positives = 159/284 (55%), Gaps = 20/284 (7%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQ------DRRFKNRELEIMKLISHPNLIDLKYY 146
+G G++G+V ET E V +KK+ D + RE+++++ + H N+I ++
Sbjct: 44 IGRGAYGIVCSVLDTETNELVAMKKIANAFDNHMDAKRTLREIKLLRHLDHENIIAIRDV 103
Query: 147 F---LEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQ 203
L + ++Y++ + M L+Q ++ SL + +Y +++QL + L Y+H
Sbjct: 104 VPPPLRRQFSDVYIS--TELMDTDLHQIIRSNQSLSEEHCQY----FLYQLLRGLKYIHS 157
Query: 204 VVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGATN 263
N+ HRD+KP N+L++ + L KICD G A+ N+ Y+ +R+YRAPEL+ +++
Sbjct: 158 A-NIIHRDLKPSNLLLNANCDL-KICDFGLARPTSENDFMTEYVVTRWYRAPELLLNSSD 215
Query: 264 YTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEI-CSMNENYSEH- 321
YT ID+WS GC+ EL+ +P+FPG+ + Q+ + ++LGTPT ++ + NE+ +
Sbjct: 216 YTAAIDVWSVGCIFMELMNRKPLFPGKDHVHQMRLLTELLGTPTESDLGFTHNEDAKRYI 275
Query: 322 -KFPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSALQCM 364
+ P PL ++F IDL+ ++ +DPN R + Q +
Sbjct: 276 RQLPNFPRQPLAKLFSHVNPMAIDLVDRMLTFDPNRRITVEQAL 319
>At2g43790 [T] KOG0660 Mitogen-activated protein kinase
Length = 395
Score = 153 bits (387), Expect = 4e-37
Identities = 86/284 (30%), Positives = 157/284 (55%), Gaps = 21/284 (7%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQ------DRRFKNRELEIMKLISHPNLIDLKYY 146
+G G++G+V ET E V IKK+ D + RE+++++ + H N++ ++
Sbjct: 69 IGKGAYGIVCSAMNSETNESVAIKKIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDI 128
Query: 147 F---LEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQ 203
L + ++Y+ + M L+Q ++ +Q + + +++Q+ + L Y+H
Sbjct: 129 IPPPLRNAFNDVYI--AYELMDTDLHQIIRS----NQALSEEHCQYFLYQILRGLKYIHS 182
Query: 204 VVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGATN 263
NV HRD+KP N+L++ + L KICD G A+ ++ Y+ +R+YRAPEL+ +++
Sbjct: 183 A-NVLHRDLKPSNLLLNANCDL-KICDFGLARVTSESDFMTEYVVTRWYRAPELLLNSSD 240
Query: 264 YTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENYSEHKF 323
YT ID+WS GC+ EL+ +P+FPG + QL +++++GTP+ EE+ +NEN ++
Sbjct: 241 YTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPSEEELEFLNEN-AKRYI 299
Query: 324 PQIRPIPLNRI---FKKETQETIDLLYHIMKYDPNIRYSALQCM 364
Q+ P P I F IDL+ ++ +DP R + L +
Sbjct: 300 RQLPPYPRQSITDKFPTVHPLAIDLIEKMLTFDPRRRITVLDAL 343
>At1g73690 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 398
Score = 153 bits (387), Expect = 4e-37
Identities = 100/297 (33%), Positives = 158/297 (52%), Gaps = 23/297 (7%)
Query: 91 EIVGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN------RELEIMKLISHPNLIDLK 144
E++G G++GVVF+ + GE V IKK+ + + RE++++K + HP++I+L
Sbjct: 15 EVLGQGTYGVVFKATDTKNGETVAIKKIRLGKEKEGVNVTALREIKLLKELKHPHIIELI 74
Query: 145 YYFLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQV 204
F + + L+++ ++M L +++ P D +K Y+ + K L Y H
Sbjct: 75 DAFPHKEN----LHIVFEFMETDLEAVIRDRNLYLSPGD---VKSYLQMILKGLEYCHGK 127
Query: 205 VNVCHRDIKPQNILVDPDTLLLKICDLGSAKQL-KPNEPNVSYICSRYYRAPELIFGATN 263
V HRD+KP N+L+ P+ L K+ D G A+ P + +R+YRAPEL+FGA
Sbjct: 128 W-VLHRDMKPNNLLIGPNGQL-KLADFGLARIFGSPGRKFTHQVFARWYRAPELLFGAKQ 185
Query: 264 YTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSM--NENYSEH 321
Y +D+W+AGC+ AELLL +P G S IDQL +I GTP ++ M +Y E+
Sbjct: 186 YDGAVDVWAAGCIFAELLLRRPFLQGNSDIDQLSKIFAAFGTPKADQWPDMICLPDYVEY 245
Query: 322 KFPQIRPIP-LNRIFKKETQETIDLLYHIMKYDPNIRYSALQCMFNSTYFTDIVSNT 377
+F P P L + +++ +DLL + YDP R S Q + YFT S T
Sbjct: 246 QFV---PAPSLRSLLPTVSEDALDLLSKMFTYDPKSRISIQQAL-KHRYFTSAPSPT 298
>SPBC19F8.07 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 335
Score = 153 bits (386), Expect = 5e-37
Identities = 98/281 (34%), Positives = 152/281 (53%), Gaps = 19/281 (6%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN-------RELEIMKLISHPNLIDLKY 145
VG G++ VVF + KET V IKK+ + +FK+ RE++ ++ H N+I+L
Sbjct: 17 VGEGTYAVVFLGRQKETNRRVAIKKI-KVGQFKDGIDISALREIKFLRESRHDNVIELVD 75
Query: 146 YFLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVV 205
F +S+ LN+I++++ L +K+ + QP IK +M L + L+++H
Sbjct: 76 VFSTKSN----LNIILEFLDSDLEMLIKDKFIVFQPA---HIKSWMVMLLRGLHHIHSRF 128
Query: 206 NVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGATNYT 265
+ HRD+KP N+L+ D +L K+ D G ++ + +R+YR PEL G +Y
Sbjct: 129 -ILHRDLKPNNLLISSDGVL-KLADFGLSRDFGTPSHMSHQVITRWYRPPELFMGCRSYG 186
Query: 266 TKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNE--NYSEHKF 323
T +D+WS GC+ AEL+L P PGES +DQL I + LGTP E I SM + NY E K
Sbjct: 187 TGVDMWSVGCIFAELMLRTPYLPGESDLDQLNVIFRALGTPEPEVIKSMQQLPNYVEMKH 246
Query: 324 PQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSALQCM 364
+ +F E IDLL ++ Y+P R +A Q +
Sbjct: 247 IPPPNGGMEALFSAAGHEEIDLLKMMLDYNPYRRPTAQQAL 287
>7297009 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 392
Score = 153 bits (386), Expect = 5e-37
Identities = 101/320 (31%), Positives = 167/320 (51%), Gaps = 27/320 (8%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQD------RRFKNRELEIMKLISHPNLIDLKYY 146
+G GS+GVV++ + +ETG V +K+ ++ R+ RE+ ++K + HPNL+ L
Sbjct: 10 LGEGSYGVVYKCRDRETGALVAVKRFVESEDDPAIRKIALREIRLLKNLKHPNLVSL--- 66
Query: 147 FLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVVN 206
LE ++ L+L+ ++ +++ L+ Q + K +Q + Y H+
Sbjct: 67 -LEVFRRKRRLHLVFEFCELTVLHELERH---PQGCPEHLTKQICYQTLLGVAYCHKQ-G 121
Query: 207 VCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGATNYTT 266
HRDIKP+NIL+ + K+CD G A+ L P E Y+ +R+YRAPEL+ G T Y T
Sbjct: 122 CLHRDIKPENILLTAQGQV-KLCDFGFARMLSPGENYTDYVATRWYRAPELLVGDTQYGT 180
Query: 267 KIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLG--TPTREEICSMNENYSEHKFP 324
+D+W+ GC+ AEL+ G+ ++PG S +DQL I K LG P +I NE + P
Sbjct: 181 PVDVWAIGCLFAELVRGEALWPGRSDVDQLYLIRKTLGDLLPRHIQIFGQNEYFKGITLP 240
Query: 325 QIRPI--PLNRIFKKETQE---TIDLLYHIMKYDPNIRYSALQCMFNSTYFTDIVSNTGS 379
+ P PL ++Q+ TID L + DP R+S + + +YF D ++
Sbjct: 241 -VPPTLEPLEDKMPAKSQQNPLTIDFLKKCLDKDPTKRWSC-EKLTKHSYFDDYIA---K 295
Query: 380 DSNLSLIDSLPLLHFEESEL 399
L ++SL + + +L
Sbjct: 296 QRELEHVNSLEAANLRQQQL 315
>At2g01450 [T] KOG0660 Mitogen-activated protein kinase
Length = 516
Score = 152 bits (385), Expect = 7e-37
Identities = 101/335 (30%), Positives = 177/335 (52%), Gaps = 27/335 (8%)
Query: 91 EIVGNGSFGVVFRTKVKETGEDVVIKKV------LQDRRFKNRELEIMKLISHPNLIDLK 144
E+VG GS+GVV + TG V IKK+ + D RE+++++L+ HP+++++K
Sbjct: 20 EVVGKGSYGVVASAECPHTGGKVAIKKMTNVFEHVSDAIRILREIKLLRLLRHPDIVEIK 79
Query: 145 YYFLEQSDQELY-LNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQ 203
+ L +E + ++ + M L+ LK ++ + + +++QL + L ++H
Sbjct: 80 HIMLPPCRKEFKDIYVVFELMESDLHHVLK----VNDDLTPQHHQFFLYQLLRGLKFMHS 135
Query: 204 VVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNV----SYICSRYYRAPELIF 259
+V HRD+KP+NIL + D + KICDLG A+ + P+ Y+ +R+YRAPEL
Sbjct: 136 A-HVFHRDLKPKNILANADCKI-KICDLGLARVSFTDSPSAVFWTDYVATRWYRAPELCG 193
Query: 260 GA-TNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENY 318
+NYT ID+WS GC+ AE+L G+P+FPG++ + QL + +LGTP+ + +
Sbjct: 194 SFYSNYTPAIDMWSVGCIFAEMLTGKPLFPGKNVVHQLELVTDLLGTPSPITLSRIRNEK 253
Query: 319 SEHKFPQIR---PIPLNRIFKKETQETIDLLYHIMKYDPNIRYSALQCMFNSTYFTDIVS 375
+ +R P+P F + LL ++ +DP R SA + + + YF + +
Sbjct: 254 ARKYLGNMRRKDPVPFTHKFPNIDPVALKLLQRLIAFDPKDRPSAEEALAD-PYFQGL-A 311
Query: 376 NTGSDSNLSLIDSLPLLHFEESELQGLSSNDIYRL 410
N + + I L E E + L+ +D+ L
Sbjct: 312 NVDYEPSRQPISKLEF----EFERRKLTRDDVREL 342
>At1g18040 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 391
Score = 152 bits (385), Expect = 7e-37
Identities = 100/297 (33%), Positives = 157/297 (52%), Gaps = 23/297 (7%)
Query: 91 EIVGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN------RELEIMKLISHPNLIDLK 144
E++G G++GVVF+ +T + V IKK+ ++ + RE++++K + HP++I L
Sbjct: 16 EVLGQGTYGVVFKATDTKTEQTVAIKKIRLGKQREGVNITALREIKMLKELKHPHIILLI 75
Query: 145 YYFLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQV 204
F + + L+L+ ++M L +++ P D IK Y+ FK L Y H
Sbjct: 76 DAFPHKEN----LHLVFEFMETDLEAVIRDSNIFLSPAD---IKSYLLMTFKGLAYCHDK 128
Query: 205 VNVCHRDIKPQNILVDPDTLLLKICDLGSAKQL-KPNEPNVSYICSRYYRAPELIFGATN 263
V HRD+KP N+L+ D L K+ D G A+ PN + +R+YRAPEL+FGA
Sbjct: 129 W-VLHRDMKPNNLLIGVDGQL-KLADFGLARIFGSPNRKFTHQVFARWYRAPELLFGAKQ 186
Query: 264 YTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNE--NYSEH 321
Y +D+W+ C+ AELLL +P G S IDQL +I GTP ++ + + +Y E+
Sbjct: 187 YGAAVDVWAVACIFAELLLRRPFLQGNSDIDQLSKIFAAFGTPKADQWPDLTKLPDYVEY 246
Query: 322 KFPQIRPIP-LNRIFKKETQETIDLLYHIMKYDPNIRYSALQCMFNSTYFTDIVSNT 377
+F P P L +F + + +DLL + YDP R S Q + YFT + T
Sbjct: 247 QFV---PAPSLRSLFPAVSDDALDLLSKMFTYDPKARISIKQAL-EHRYFTSAPAPT 299
>CE05377 [G] KOG0658 Glycogen synthase kinase-3
Length = 381
Score = 152 bits (384), Expect = 9e-37
Identities = 107/359 (29%), Positives = 180/359 (49%), Gaps = 48/359 (13%)
Query: 85 ISCGTPEIVGNGSFGVVFRTKVKETGE---DVVIKKVLQDRRFKNRELEIMKL-----IS 136
+S + +G+F V+R + ++VIKK R K LE+ L +
Sbjct: 24 LSLQNMNLFASGAFSNVYRGIARTESNHQMEIVIKKTWP--RHKGCPLEVKILGKLGKLK 81
Query: 137 HPNLIDLKYYFLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFK 196
H N++ L + + +Q + + L LI +Y+PM+L+Q LK+ ++ +D E+K+ ++QLF+
Sbjct: 82 HKNIVRLLFSYQKQHEGRICLGLIFEYIPMNLHQFLKDN---NRRVDIIEVKLIVWQLFR 138
Query: 197 SLNYLHQVVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPE 256
+L + +CHRDIKPQN+L + DT LLKI D GS+ P SY +RYYR PE
Sbjct: 139 GQAHLEKS-EICHRDIKPQNLLYNADTGLLKISDYGSSAIESVKTPQQSYHVTRYYRPPE 197
Query: 257 LIFGATNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNE 316
L+ G+ NY KID WS GCV ELL G G+S +Q + + G PT E++ SMN
Sbjct: 198 LLLGSKNYGCKIDTWSCGCVFGELLKGGIFLAGKSAKNQAEVVFDMFGVPTAEDVSSMNV 257
Query: 317 NYSEHK--------------------------FPQIR--PIPLNRIFKKETQETIDLLYH 348
+ +++K F + R + +I + +++++LL
Sbjct: 258 SNTKYKEIIQSYEPDTSKRTADLAYLYNQTASFQRDRRSTVYNTKIDYSDMKDSVELLRQ 317
Query: 349 IMKYDPNIRYSALQCMFNSTYFTDIVSNTGSDSNLSLIDSLPLLHFEESELQGLSSNDI 407
++ Y+P+ R ++ + N +FT + + N I + + +LQ + S D+
Sbjct: 318 VLVYNPSRRLCGIEFLTN-PFFTVLFNEKTVRFNKKKIQCVSAV-----DLQAVKSGDV 370
>ECU08g1920 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 296
Score = 151 bits (382), Expect = 2e-36
Identities = 89/279 (31%), Positives = 156/279 (55%), Gaps = 17/279 (6%)
Query: 91 EIVGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN------RELEIMKLISHPNLIDLK 144
E +G G++GVV++ + + T V +KK+ + + RE+ ++K + H +++L
Sbjct: 9 EKIGEGTYGVVYKARERNTNRVVALKKIRLENENEGIPATTIREILLLKNLKHSTIVELS 68
Query: 145 YYFLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQV 204
++ ++YL + +Y+ + L + L + ++ ++ QL ++ Y H
Sbjct: 69 DVIY--NNNKMYL--VFEYVELDLRRYLDRMSDEGRLVEEGFVRKMSQQLLTAMEYCHSR 124
Query: 205 VNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLK-PNEPNVSYICSRYYRAPELIFGATN 263
N+ HRD+KPQNILVDP + K+ D G + P + + + +YR PEL+ G
Sbjct: 125 -NIFHRDLKPQNILVDPKENI-KLADFGLGRAAGIPLRTYTTEVVTLWYRPPELLLGCKY 182
Query: 264 YTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENYSEHK- 322
Y +D+WSA C+MAE++L +P FPG+S+IDQL I KVLGTP ++ EN+ +K
Sbjct: 183 YDASVDVWSAACIMAEVVLMRPFFPGDSEIDQLFRIFKVLGTPNNSRWSNV-ENFPNYKV 241
Query: 323 -FPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSA 360
FP P+ L IF+ + + +DL+ +++YDP +R +A
Sbjct: 242 EFPVWDPVDLKTIFRGD-PDFVDLISKMLEYDPKMRMTA 279
>Hs20986529 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 151 bits (381), Expect = 2e-36
Identities = 89/285 (31%), Positives = 155/285 (54%), Gaps = 20/285 (7%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKV--LQDRRFKNRELEIMKLI---SHPNLIDLKYYF 147
+G G++G+V V IKK+ + + + R L +K++ H N+I +
Sbjct: 31 IGEGAYGMVCSAYDNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDII 90
Query: 148 LEQSDQELY-LNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVVN 206
+ +++ + ++ D M LY+ LK Q + I +++Q+ + L Y+H N
Sbjct: 91 RAPTIEQMKDVYIVQDLMETDLYKLLKT-----QHLSNDHICYFLYQILRGLKYIHSA-N 144
Query: 207 VCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVS----YICSRYYRAPELIFGAT 262
V HRD+KP N+L++ T LKICD G A+ P+ + Y+ +R+YRAPE++ +
Sbjct: 145 VLHRDLKPSNLLLNT-TCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSK 203
Query: 263 NYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEI-CSMNENYSEH 321
YT IDIWS GC++AE+L +PIFPG+ +DQL I+ +LG+P++E++ C +N +
Sbjct: 204 GYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLKHILGILGSPSQEDLNCIINLKARNY 263
Query: 322 --KFPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSALQCM 364
P +P NR+F + +DLL ++ ++P+ R Q +
Sbjct: 264 LLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQAL 308
>CE20405 [G] KOG0658 Glycogen synthase kinase-3
Length = 381
Score = 151 bits (381), Expect = 2e-36
Identities = 98/307 (31%), Positives = 158/307 (50%), Gaps = 38/307 (12%)
Query: 92 IVGNGSFGVVFRTKVKETGE---DVVIKKVLQDRRFKNRELEIMKLIS---HPNLIDLKY 145
+ G+F V+R + D+VIKK + E++I+ + H N++ L Y
Sbjct: 31 LFATGAFSNVYRGVAQTESNQEIDIVIKKTWPRHKGCPMEVKILGQLGKLKHRNIVRLLY 90
Query: 146 YFLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVV 205
+ +Q + + L LI +Y+P++LYQ LK+ ++ +D E+K+ ++QLF+ +L +
Sbjct: 91 SYQKQHEGRICLALIFEYIPLNLYQFLKD---KNRRIDIVEVKLIVWQLFRGQAHLEKA- 146
Query: 206 NVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGATNYT 265
++CHRDIKPQN+L + +T LLKI D GS+ P SY +RYYR PELI G+ Y
Sbjct: 147 DICHRDIKPQNLLYNAETGLLKISDFGSSSIQSTKSPQQSYHVTRYYRPPELILGSKYYG 206
Query: 266 TKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMN---------- 315
KID WS GCV ELL G I G+S +Q I +LG PT ++ SM
Sbjct: 207 CKIDTWSCGCVFGELLKGGIILAGKSSNNQAEVIFDMLGYPTDSDVSSMKVSSTKLQEVL 266
Query: 316 ENYSEHKFPQIRPIPL------------------NRIFKKETQETIDLLYHIMKYDPNIR 357
++Y +K + +I + + +E++ +L I+ Y+PN R
Sbjct: 267 DSYEYNKSKTTADLTYLYTQTVIYQKDRRTTVYNTKIEQDDMKESVAVLLQILVYNPNKR 326
Query: 358 YSALQCM 364
S ++ +
Sbjct: 327 LSGIEIL 333
>Hs20986531 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 150 bits (380), Expect = 3e-36
Identities = 89/285 (31%), Positives = 155/285 (54%), Gaps = 20/285 (7%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKV--LQDRRFKNRELEIMKLI---SHPNLIDLKYYF 147
+G G++G+V V IKK+ + + + R L +K++ H N+I +
Sbjct: 31 IGEGAYGMVCSAYDNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDII 90
Query: 148 LEQSDQELY-LNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVVN 206
+ +++ + ++ D M LY+ LK Q + I +++Q+ + L Y+H N
Sbjct: 91 RAPTIEQMKDVYIVQDLMETDLYKLLKT-----QHLSNDHICYFLYQILRGLKYIHSA-N 144
Query: 207 VCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVS----YICSRYYRAPELIFGAT 262
V HRD+KP N+L++ T LKICD G A+ P+ + Y+ +R+YRAPE++ +
Sbjct: 145 VLHRDLKPSNLLLNT-TCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSK 203
Query: 263 NYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEI-CSMNENYSEH 321
YT IDIWS GC++AE+L +PIFPG+ +DQL I+ +LG+P++E++ C +N +
Sbjct: 204 GYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNY 263
Query: 322 --KFPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSALQCM 364
P +P NR+F + +DLL ++ ++P+ R Q +
Sbjct: 264 LLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQAL 308
>7290565 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 353
Score = 150 bits (380), Expect = 3e-36
Identities = 95/291 (32%), Positives = 154/291 (52%), Gaps = 22/291 (7%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQD---------RRFKNRELEIMKLISHPNLIDL 143
+G G F V++ + T + V +KK+ + R RE++I++ + H N+I L
Sbjct: 18 LGEGQFATVYKARDTVTNQIVAVKKIKKGSREDARDGINRTALREIKILQELQHENIIGL 77
Query: 144 KYYFLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQ 203
F + S+ ++L+ D+M L +K+ + + + IK Y K L YLH
Sbjct: 78 VDVFGQLSN----VSLVFDFMDTDLEVIIKDNKII---LTQANIKAYAIMTLKGLEYLH- 129
Query: 204 VVN-VCHRDIKPQNILVDPDTLLLKICDLGSAKQL-KPNEPNVSYICSRYYRAPELIFGA 261
+N + HRD+KP N+LV+ D +L KI D G AK PN ++ +R+YR+PEL+FGA
Sbjct: 130 -LNWILHRDLKPNNLLVNSDGIL-KIGDFGLAKSFGSPNRIYTHHVVTRWYRSPELLFGA 187
Query: 262 TNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENYSEH 321
Y T +D+W+ GC++AEL+L P PG+S +DQL I LGTPT E +++ +
Sbjct: 188 RQYGTGVDMWAVGCILAELMLRVPFMPGDSDLDQLTRIFSTLGTPTEAEWPHLSKLHDYL 247
Query: 322 KFPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSALQCMFNSTYFTD 372
+F PL+ IF + I L+ + +P R S + + + YF +
Sbjct: 248 QFRNFPGTPLDNIFTAAGNDLIHLMQRLFAMNPLRRVSCREAL-SMPYFAN 297
>Hs4826675 [UT] KOG0662 Cyclin-dependent kinase CDK5
Length = 292
Score = 149 bits (375), Expect = 1e-35
Identities = 104/297 (35%), Positives = 162/297 (54%), Gaps = 31/297 (10%)
Query: 91 EIVGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN------RELEIMKLISHPNLIDLK 144
E +G G++G VF+ K +ET E V +K+V D + RE+ ++K + H N++ L
Sbjct: 8 EKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKNIVRL- 66
Query: 145 YYFLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQV 204
+ + SD++L L+ ++ L K F S + +D +K ++FQL K L + H
Sbjct: 67 -HDVLHSDKKL--TLVFEFCDQDLK---KYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSR 120
Query: 205 VNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLK-PNEPNVSYICSRYYRAPELIFGATN 263
NV HRD+KPQN+L++ + L K+ D G A+ P + + + +YR P+++FGA
Sbjct: 121 -NVLHRDLKPQNLLINRNGEL-KLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKL 178
Query: 264 YTTKIDIWSAGCVMAELL-LGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENYSEHK 322
Y+T ID+WSAGC+ AEL G+P+FPG DQL I ++LGTPT E+ SM K
Sbjct: 179 YSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMT------K 232
Query: 323 FPQIRPIP-------LNRIFKKETQETIDLLYHIMKYDPNIRYSALQCMFNSTYFTD 372
P +P P L + K DLL +++K +P R SA + + YF+D
Sbjct: 233 LPDYKPYPMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEAL-QHPYFSD 288
>Hs20986501 [T] KOG0660 Mitogen-activated protein kinase
Length = 816
Score = 149 bits (375), Expect = 1e-35
Identities = 92/286 (32%), Positives = 153/286 (53%), Gaps = 22/286 (7%)
Query: 91 EIVGNGSFGVVFRTKVKETGEDVVIKK------VLQDRRFKNRELEIMKLISHPNLIDLK 144
E +GNG++GVV + + TG+ V IKK V+ + + REL+I+K H N+I +K
Sbjct: 59 ETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDNIIAIK 118
Query: 145 YYFLEQSDQELYLNL--IVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLH 202
+ ++ ++D M L+Q I QP+ ++ +++QL + L Y+H
Sbjct: 119 DILRPTVPYGEFKSVYVVLDLMESDLHQ----IIHSSQPLTLEHVRYFLYQLLRGLKYMH 174
Query: 203 QVVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQL--KPNEPN---VSYICSRYYRAPEL 257
V HRD+KP N+LV+ + LKI D G A+ L P E Y+ +R+YRAPEL
Sbjct: 175 SA-QVIHRDLKPSNLLVN-ENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAPEL 232
Query: 258 IFGATNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNEN 317
+ YT ID+WS GC+ E+L + +FPG++ + QL I+ VLGTP+ I ++
Sbjct: 233 MLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAE 292
Query: 318 YSE---HKFPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSA 360
P +P+P ++ ++ + LL +++++P+ R SA
Sbjct: 293 RVRAYIQSLPPRQPVPWETVYPGADRQALSLLGRMLRFEPSARISA 338
>Hs20986497 [T] KOG0660 Mitogen-activated protein kinase
Length = 816
Score = 149 bits (375), Expect = 1e-35
Identities = 92/286 (32%), Positives = 153/286 (53%), Gaps = 22/286 (7%)
Query: 91 EIVGNGSFGVVFRTKVKETGEDVVIKK------VLQDRRFKNRELEIMKLISHPNLIDLK 144
E +GNG++GVV + + TG+ V IKK V+ + + REL+I+K H N+I +K
Sbjct: 59 ETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDNIIAIK 118
Query: 145 YYFLEQSDQELYLNL--IVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLH 202
+ ++ ++D M L+Q I QP+ ++ +++QL + L Y+H
Sbjct: 119 DILRPTVPYGEFKSVYVVLDLMESDLHQ----IIHSSQPLTLEHVRYFLYQLLRGLKYMH 174
Query: 203 QVVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQL--KPNEPN---VSYICSRYYRAPEL 257
V HRD+KP N+LV+ + LKI D G A+ L P E Y+ +R+YRAPEL
Sbjct: 175 SA-QVIHRDLKPSNLLVN-ENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAPEL 232
Query: 258 IFGATNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNEN 317
+ YT ID+WS GC+ E+L + +FPG++ + QL I+ VLGTP+ I ++
Sbjct: 233 MLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAE 292
Query: 318 YSE---HKFPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSA 360
P +P+P ++ ++ + LL +++++P+ R SA
Sbjct: 293 RVRAYIQSLPPRQPVPWETVYPGADRQALSLLGRMLRFEPSARISA 338
>Hs20562757 [T] KOG0660 Mitogen-activated protein kinase
Length = 379
Score = 149 bits (375), Expect = 1e-35
Identities = 89/288 (30%), Positives = 157/288 (53%), Gaps = 22/288 (7%)
Query: 91 EIVGNGSFGVVFRTKVKETGEDVVIKKV--LQDRRFKNR---ELEIMKLISHPNLIDLKY 145
+ +G G++G+V V IKK+ + + + R E++I+ H N+I ++
Sbjct: 46 QYIGEGAYGMVSSAYDHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRFRHENVIGIRD 105
Query: 146 YFLEQSDQELY-LNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQV 204
+ + + + ++ D M LY+ LK Q + I +++Q+ + L Y+H
Sbjct: 106 ILRASTLEAMRDVYIVQDLMETDLYKLLKS-----QQLSNDHICYFLYQILRGLKYIHSA 160
Query: 205 VNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVS----YICSRYYRAPELIFG 260
NV HRD+KP N+L++ T LKICD G A+ P + Y+ +R+YRAPE++
Sbjct: 161 -NVLHRDLKPSNLLINT-TCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLN 218
Query: 261 ATNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEI-CSMN---E 316
+ YT IDIWS GC++AE+L +PIFPG+ +DQL I+ +LG+P++E++ C +N
Sbjct: 219 SKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKAR 278
Query: 317 NYSEHKFPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSALQCM 364
NY + P + ++F K + +DLL ++ ++PN R + + +
Sbjct: 279 NYLQ-SLPSKTKVAWAKLFPKSDSKALDLLDRMLTFNPNKRITVEEAL 325
>Hs16936528 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 298
Score = 148 bits (374), Expect = 1e-35
Identities = 97/294 (32%), Positives = 163/294 (54%), Gaps = 23/294 (7%)
Query: 91 EIVGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN------RELEIMKLISHPNLIDLK 144
E +G G++GVV++ + K TGE V +KK+ D + RE+ ++K ++HPN++ L
Sbjct: 8 EKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKL- 66
Query: 145 YYFLEQSDQELYLNLIVDYMPMSLYQRLKEFI--SLHQPMDRYEIKIYMFQLFKSLNYLH 202
L+ E L L+ ++ L+Q LK+F+ S + IK Y+FQL + L + H
Sbjct: 67 ---LDVIHTENKLYLVFEF----LHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCH 119
Query: 203 QVVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLK-PNEPNVSYICSRYYRAPELIFGA 261
V HRD+KPQN+L++ + + K+ D G A+ P + + +YRAPE++ G
Sbjct: 120 SH-RVLHRDLKPQNLLINTEGAI-KLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGC 177
Query: 262 TNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENYSEH 321
Y+T +DIWS GC+ AE++ + +FPG+S+IDQL I + LGTP E + + ++
Sbjct: 178 KYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPD-EVVWPGVTSMPDY 236
Query: 322 K--FPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSALQCMFNSTYFTDI 373
K FP+ +++ ++ LL ++ YDPN R SA + + +F D+
Sbjct: 237 KPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAH-PFFQDV 289
>CE06686 [T] KOG0660 Mitogen-activated protein kinase
Length = 377
Score = 148 bits (374), Expect = 1e-35
Identities = 93/284 (32%), Positives = 151/284 (52%), Gaps = 22/284 (7%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKK-------VLQDRRFKNRELEIMKLISHPNLIDLKY 145
+G G++G V + +G V IKK ++ RR REL +++ + H N+IDL
Sbjct: 41 IGTGAYGTVCAAECTRSGTRVAIKKFNRPFQSIIHARR-TYRELRLLRCMCHENIIDLLD 99
Query: 146 YFLEQSDQELYLNLIVD--YMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQ 203
F + +N I D ++ M + L + + + D + I+ ++Q+ + L Y+H
Sbjct: 100 VFTPNEN----VNDIEDVYFVSMLMGADLSNILKIQRLNDDH-IQFLVYQILRGLKYIHS 154
Query: 204 VVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGATN 263
++ HRD+KP NI V+ D L KI D G A+Q + Y+ +R+YRAPE++ +
Sbjct: 155 A-DIIHRDLKPSNIAVNEDCEL-KILDFGLARQT--DSEMTGYVATRWYRAPEIMLNWMH 210
Query: 264 YTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTRE---EICSMNENYSE 320
YT +D+WS GC++AEL+ G+ +FPG IDQL I+ V GTP E +I S
Sbjct: 211 YTQTVDVWSVGCILAELITGKTLFPGSDHIDQLTRIMSVTGTPDEEFLKKISSEEARNYI 270
Query: 321 HKFPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSALQCM 364
P++ R+F + T + IDLL ++ DP+ R +A + M
Sbjct: 271 RNLPKMTRRDFKRLFAQATPQAIDLLEKMLHLDPDRRPTAKEAM 314
>CE06762 [T] KOG0660 Mitogen-activated protein kinase
Length = 367
Score = 147 bits (372), Expect = 2e-35
Identities = 98/311 (31%), Positives = 160/311 (50%), Gaps = 32/311 (10%)
Query: 88 GTP----EIVGNGSFGVVFRTKVKETGEDVVIKKVLQD------RRFKNRELEIMKLISH 137
GTP E VG G++GVV + + V IKK+ + + RE+ I++ + H
Sbjct: 54 GTPYLAEENVGAGAYGVVCKAMDTRNKKQVAIKKIPRAFTAHTLAKRSLREVRILRELLH 113
Query: 138 PNLIDLKYYFLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKS 197
N+I + F + + L++D M L+Q L Q + + + +QL +
Sbjct: 114 ENIIAVLDMFTAEGAHGKDIYLVMDLMETDLHQILHS----RQTLMEQHFQYFFYQLLRG 169
Query: 198 LNYLHQVVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKP-----NEPNVS-----YI 247
L YLH + HRD+KP N+L++ D LL +I D G A+ ++ NV Y+
Sbjct: 170 LKYLHSA-GIIHRDLKPSNLLLNGDCLL-RIADFGMARAYASASTVRDDANVGGHMTQYV 227
Query: 248 CSRYYRAPELIFGATNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPT 307
+R+YRAPE++F Y TK+D+WSAGC+ AE+LL + +FPG+ + Q+ I+ LG+P
Sbjct: 228 STRWYRAPEILFSMVEYDTKVDLWSAGCIFAEMLLRRQLFPGKDSVSQIKMIVYYLGSPE 287
Query: 308 REEICSMNENY---SEHKFPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSA---L 361
E I + + S + P+P + IF K + E +++ ++++ P RYSA L
Sbjct: 288 EEVINRITSDLVRDSIEACGRKTPLPFSAIFPKASPEARNMVSYLLQISPWKRYSADQIL 347
Query: 362 QCMFNSTYFTD 372
Q F + Y D
Sbjct: 348 QHPFMAQYHND 358
>At1g33770 [D] KOG0600 Cdc2-related protein kinase
Length = 614
Score = 147 bits (372), Expect = 2e-35
Identities = 98/297 (32%), Positives = 162/297 (53%), Gaps = 32/297 (10%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVL------QDRRFKNRELEIMKLISHPNLIDLKYY 146
+G G++ +V++ + ETG+ V +KKV + RF RE+ I++ + HPN++ L+
Sbjct: 147 IGQGTYSIVYKARDLETGKIVAMKKVRFANMDPESVRFMAREINILRKLDHPNVMKLQC- 205
Query: 147 FLEQSDQELYLNLIVDYMPMSLYQ-RLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVV 205
L S L+L+ +YM L L+ + +P +IK +M QL L + H
Sbjct: 206 -LVTSKLSGSLHLVFEYMEHDLSGLALRPGVKFTEP----QIKCFMKQLLCGLEHCHSR- 259
Query: 206 NVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNE--PNVSYICSRYYRAPELIFGATN 263
+ HRDIK N+LV+ D +L KI D G A KP++ P S + + +YRAPEL+ G+T
Sbjct: 260 GILHRDIKGSNLLVNNDGVL-KIGDFGLASFYKPDQDQPLTSRVVTLWYRAPELLLGSTE 318
Query: 264 YTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENYSEHKF 323
Y ID+WS GC++AEL + +PI PG ++++Q+ +I K+ G+P+ E ++ KF
Sbjct: 319 YGPAIDLWSVGCILAELFVCKPIMPGRTEVEQMHKIFKLCGSPS-------EEFWNTTKF 371
Query: 324 PQIRPI----PLNRI----FKKETQETIDLLYHIMKYDPNIRYSALQCMFNSTYFTD 372
PQ P R+ FK + ++DLL ++ +P R SA + + + T+
Sbjct: 372 PQATSYKPQHPYKRVLLETFKNLSSSSLDLLDKLLSVEPEKRCSASSTLLSEFFTTE 428
>Hs17461944 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 385
Score = 145 bits (367), Expect = 8e-35
Identities = 92/289 (31%), Positives = 154/289 (52%), Gaps = 19/289 (6%)
Query: 94 GNGSFGVVFRTKVKETGEDVVIKKVLQD------RRFKNRELEIMKLISHPNLIDLKYYF 147
G GS+GVVF+ + K +G+ V +KK ++ ++ RE+ ++K + HPNL++L
Sbjct: 11 GEGSYGVVFKCRNKTSGQVVAVKKFVESEDDPVVKKIALREIRMLKQLKHPNLVNL---- 66
Query: 148 LEQSDQELYLNLIVDYMPMSLYQRLKEF---ISLHQPMDRYEIKIYMFQLFKSLNYLHQV 204
+E ++ ++L+ +Y +L L+ + + R +L N + +
Sbjct: 67 IEVFRRKRKMHLVFEYCDHTLLNELERNPNGMDSDSIVGRLRSVADRSRLAPKNNQI-MI 125
Query: 205 VNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGATNY 264
+ HRDIKP+NIL+ ++ KICD G A+ L P + Y+ +R+YRAPEL+ G T Y
Sbjct: 126 LQCIHRDIKPENILITKQGII-KICDFGFAQILIPGDAYTDYVATRWYRAPELLVGDTQY 184
Query: 265 TTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLG--TPTREEICSMNENYSEHK 322
+ +DIW+ GCV AELL GQP++PG+S +DQL II+ LG P + I N +
Sbjct: 185 GSSVDIWAIGCVFAELLTGQPLWPGKSDVDQLYLIIRTLGKLIPRHQSIFKSNGFFHGIS 244
Query: 323 FPQIRPI-PLNRIFKKETQETIDLLYHIMKYDPNIRYSALQCMFNSTYF 370
P+ + L F ++ + +K +P+ R + Q + S+YF
Sbjct: 245 IPEPEDMETLEEKFSDVHPVALNFMKGCLKMNPDDRLTCSQ-LLESSYF 292
>At3g54180 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 309
Score = 145 bits (367), Expect = 8e-35
Identities = 93/291 (31%), Positives = 160/291 (54%), Gaps = 27/291 (9%)
Query: 91 EIVGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN------RELEIMKLISHPNLIDLK 144
E VG G++G V++ K TG+ V +KK + + RE+ +++++S ++ ++
Sbjct: 8 EKVGEGTYGKVYKAMEKGTGKLVALKKTRLEMDEEGIPPTALREISLLQMLS-TSIYVVR 66
Query: 145 YYFLEQSDQ--------ELYLNLIVDYMPMSLYQRLKEFISLHQ------PMDRYEIKIY 190
+E Q + L L+ +Y+ L K+FI ++ P++ + I+
Sbjct: 67 LLCVEHVHQPSTKSQSTKSNLYLVFEYLDTDL----KKFIDSYRKGPNPKPLEPFLIQKL 122
Query: 191 MFQLFKSLNYLHQVVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLK-PNEPNVSYICS 249
MFQL K + + H V HRD+KPQN+L+ D LLKI DLG + P + I +
Sbjct: 123 MFQLCKGVAHCHSH-GVLHRDLKPQNLLLVKDKELLKIADLGLGRAFTVPLKSYTHEIVT 181
Query: 250 RYYRAPELIFGATNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTRE 309
+YRAPE++ G+T+Y+T +D+WS GC+ AE++ Q +FPG+S+ QL+ I ++LGTPT +
Sbjct: 182 LWYRAPEVLLGSTHYSTGVDMWSVGCIFAEMVRRQALFPGDSEFQQLLHIFRLLGTPTEQ 241
Query: 310 EICSMNENYSEHKFPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSA 360
+ ++ H +P+ P L + + +DLL ++KY+P R SA
Sbjct: 242 QWPGVSTLRDWHVYPKWEPQDLTLAVPSLSPQGVDLLTKMLKYNPAERISA 292
>At1g59580 [T] KOG0660 Mitogen-activated protein kinase
Length = 376
Score = 145 bits (367), Expect = 8e-35
Identities = 95/288 (32%), Positives = 159/288 (54%), Gaps = 27/288 (9%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKNR--------ELEIMKLISHPNLIDLK 144
+G G++GVV + +E+ E V IKK+ F+NR EL++++ + H N++ LK
Sbjct: 38 IGRGAYGVVCSSVNRESNERVAIKKI--HNVFENRIDALRTLRELKLLRHLRHENVVALK 95
Query: 145 YYFL---EQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYL 201
+ ++S +++YL + + M L+Q +K Q + + ++FQL + L Y+
Sbjct: 96 DVMMANHKRSFKDVYL--VYELMDTDLHQIIKS----SQVLSNDHCQYFLFQLLRGLKYI 149
Query: 202 HQVVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVS-YICSRYYRAPELIFG 260
H N+ HRD+KP N+LV+ + L KICD G A+ ++ Y+ +R+YRAPEL+
Sbjct: 150 HSA-NILHRDLKPGNLLVNANCDL-KICDFGLARTSNTKGQFMTEYVVTRWYRAPELLLC 207
Query: 261 ATNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENYSE 320
NY T ID+WS GC+ AELL +P+FPG ++Q+ II +LG+ REE +N
Sbjct: 208 CDNYGTSIDVWSVGCIFAELLGRKPVFPGTECLNQIKLIINILGS-QREEDLEFIDNPKA 266
Query: 321 HKFPQIRP----IPLNRIFKKETQETIDLLYHIMKYDPNIRYSALQCM 364
++ + P I +R++ IDLL ++ DP+ R S + +
Sbjct: 267 KRYIESLPYSPGISFSRLYPGANVLAIDLLQKMLVLDPSKRISVTEAL 314
>At4g36450 [T] KOG0660 Mitogen-activated protein kinase
Length = 361
Score = 145 bits (365), Expect = 1e-34
Identities = 100/291 (34%), Positives = 156/291 (53%), Gaps = 32/291 (10%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKNR--------ELEIMKLISHPNLIDLK 144
+G G++GVV + ET E V IKK+ F+NR EL++++ + H N+I LK
Sbjct: 38 IGRGAYGVVCSSINSETNERVAIKKI--HNVFENRIDALRTLRELKLLRHVRHENVISLK 95
Query: 145 YYFL---EQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYL 201
L S +++YL + + M L Q +K SL +Y ++FQL + L YL
Sbjct: 96 DVMLPTHRYSFRDVYL--VYELMDSDLNQIIKSSQSLSDDHCKY----FLFQLLRGLKYL 149
Query: 202 HQVVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGA 261
H N+ HRD+KP N+LV+ + L KICD G A+ + + Y+ +R+YRAPEL+
Sbjct: 150 HSA-NILHRDLKPGNLLVNANCDL-KICDFGLARTYE--QFMTEYVVTRWYRAPELLLCC 205
Query: 262 TNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENYSEH 321
NY T ID+WS GC+ AE+L +PIFPG ++QL II V+G+ ++ +N
Sbjct: 206 DNYGTSIDVWSVGCIFAEILGRKPIFPGTECLNQLKLIINVVGSQQDWDL-QFIDNQKAR 264
Query: 322 KFPQIRPIPLNR------IFKKETQETIDLLYHIMKYDPNIRYSALQCMFN 366
+F I+ +P ++ I+ IDLL ++ +DP R S + +
Sbjct: 265 RF--IKSLPFSKGTHFSHIYPHANPLAIDLLQRMLVFDPTKRISVSDALLH 313
>7300650 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 314
Score = 145 bits (365), Expect = 1e-34
Identities = 96/315 (30%), Positives = 164/315 (51%), Gaps = 36/315 (11%)
Query: 91 EIVGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN------RELEIMKLISHPNLIDLK 144
E +G G++G+V++ + TG+DV +KK+ + + RE+ ++K + HPN++ L
Sbjct: 12 EKIGEGTYGIVYKARSNSTGQDVALKKIRLEGETEGVPSTAIREISLLKNLKHPNVVQL- 70
Query: 145 YYFLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQV 204
+ + S LY+ I +Y+ M L + + + + P IK YM Q+ ++ + H
Sbjct: 71 -FDVVISGNNLYM--IFEYLNMDLKKLMDKKKDVFTPQ---LIKSYMHQILDAVGFCH-T 123
Query: 205 VNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLK-PNEPNVSYICSRYYRAPELIFGATN 263
+ HRD+KPQN+LVD + K+ D G A+ P + + +YRAPE++ G
Sbjct: 124 NRILHRDLKPQNLLVDTAGKI-KLADFGLARAFNVPMRAYTHEVVTLWYRAPEILLGTKF 182
Query: 264 YTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENYS-EHK 322
Y+T +DIWS GC+ +E+++ + +FPG+S+IDQL I + L TP + + + K
Sbjct: 183 YSTGVDIWSLGCIFSEMIMRRSLFPGDSEIDQLYRIFRTLSTPDETNWPGVTQLPDFKTK 242
Query: 323 FPQIR----PIPLNRIFKKETQETIDLLYHIMKYDPNIRYSALQCM----FNSTYFTDIV 374
FP+ P P+ E +L+ ++ YDPN+R SA + F + D V
Sbjct: 243 FPRWEGTNMPQPITE------HEAHELIMSMLCYDPNLRISAKDALQHAYFRNVQHVDHV 296
Query: 375 S-----NTGSDSNLS 384
+ N GS S L+
Sbjct: 297 ALPVDPNAGSASRLT 311
>At4g13020 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 443
Score = 144 bits (363), Expect = 2e-34
Identities = 96/291 (32%), Positives = 163/291 (55%), Gaps = 24/291 (8%)
Query: 91 EIVGNGSFGVVFRTKVKETGEDVVIKKVLQ-----DRRFKNRELEIMKLISHPNLIDLKY 145
E +G+G+ G V++ ET E V +KK+ + + RE++ ++ ++HP++I LK
Sbjct: 16 EELGDGTCGSVYKAVNLETYEVVAVKKMKRKFYYWEECVNLREVKALRKLNHPHIIKLKE 75
Query: 146 YFLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVV 205
E ++ L I + M +LY +KE +P EI+ +M Q+ + L ++H+
Sbjct: 76 IVREHNE----LFFIFECMDHNLYHIMKE---RERPFSEGEIRSFMSQMLQGLAHMHKN- 127
Query: 206 NVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGATNYT 265
HRD+KP+N+LV + +LKI D G A+++ P Y+ +R+YRAPE++ ++ YT
Sbjct: 128 GYFHRDLKPENLLVTNN--ILKIADFGLAREVASMPPYTEYVSTRWYRAPEVLLQSSLYT 185
Query: 266 TKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTP---TREEICSMNE--NYSE 320
+D+W+ G ++AEL P+FPGES+IDQL +I VLG P T E S++ + S
Sbjct: 186 PAVDMWAVGAILAELYALTPLFPGESEIDQLYKICCVLGKPDWTTFPEAKSISRIMSISH 245
Query: 321 HKFPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSALQCMFNSTYFT 371
+FPQ R + + E IDL+ + +DP R +A + + N +F+
Sbjct: 246 TEFPQTR---IADLLPNAAPEAIDLINRLCSWDPLKRPTADEAL-NHPFFS 292
>7303804 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 387
Score = 144 bits (363), Expect = 2e-34
Identities = 105/348 (30%), Positives = 170/348 (48%), Gaps = 31/348 (8%)
Query: 47 LHSKNSHGNDVKIVPDEDEVITRRTVVKGHSN------PEESVVISCGTPEI------VG 94
+ S S+ D PD ITR+ + + PE+++ C VG
Sbjct: 1 MSSLKSNDVDTNPAPDPQAPITRKGFLMSLNTGTPMPIPEQNLFGRCRPVSEFEKLNRVG 60
Query: 95 NGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN------RELEIMKLISHPNLIDLKYYFL 148
GS+G+V+R + + E V +KKV D+ RE+ I+K H N++ L+ +
Sbjct: 61 EGSYGIVYRARDTRSNEIVALKKVRMDQEKDGLPISGLREIMILKQCHHENIVRLREVVV 120
Query: 149 EQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVVNVC 208
+S ++L ++D+ L L ++ QP E+K Q+ K+L YLH +
Sbjct: 121 GKSLDSIFL--VMDFCEQDLASVLD---NMSQPFTESEVKCITLQVLKALKYLHSRFMI- 174
Query: 209 HRDIKPQNILVDPDTLLLKICDLGSAKQLK-PNEPNVSYICSRYYRAPELIFGATNYTTK 267
HRD+K N+L+ D +K+ D G A+ P +P + + +YRAPEL+ G +TT
Sbjct: 175 HRDLKVSNLLMT-DKGCIKVADFGLARMFSNPPKPMTPQMVTLWYRAPELLLGCRTHTTA 233
Query: 268 IDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENYSEHKFPQIR 327
+D+W+ GC++ ELLLG+P+ PG S+I QL II +LG P+ + + F +
Sbjct: 234 VDMWAFGCILGELLLGKPLLPGNSEIAQLDMIIDLLGAPSESIWPGFADLPAVQNF-TLS 292
Query: 328 PIPLNRI---FKKETQETIDLLYHIMKYDPNIRYSALQCMFNSTYFTD 372
P N + F Q +LL + Y+P R +A +C+ S YF D
Sbjct: 293 QQPYNNLTPKFHMIGQSGRNLLNILFIYNPKTRATAEECL-KSKYFVD 339
>CE00315 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 332
Score = 144 bits (362), Expect = 3e-34
Identities = 96/299 (32%), Positives = 168/299 (56%), Gaps = 25/299 (8%)
Query: 91 EIVGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN------RELEIMKLISHPNLIDLK 144
E +G G++GVV++ K + T V +KK+ + + RE+ ++K + HPN++ L+
Sbjct: 26 EKIGEGTYGVVYKGKNRRTNAMVAMKKIRLESEDEGVPSTAVREISLLKELQHPNVVGLE 85
Query: 145 YYFLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQV 204
+ QE L LI +++ L +R + + + + +K Y FQ+ +++ + HQ
Sbjct: 86 AVIM----QENRLFLIFEFLSFDL-KRYMDQLGKDEYLPLETLKSYTFQILQAMCFCHQR 140
Query: 205 VNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLK-PNEPNVSYICSRYYRAPELIFGATN 263
V HRD+KPQN+LVD + + K+ D G A+ + P + + +YRAPE++ GA
Sbjct: 141 -RVIHRDLKPQNLLVDNNGAI-KLADFGLARAIGIPIRVYTHEVVTLWYRAPEILMGAQR 198
Query: 264 YTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENYSEHK- 322
Y+ +D+WS GC+ AE+ +P+F G+S+ID+L I +VLGTPT E + E+ ++K
Sbjct: 199 YSMGVDMWSIGCIFAEMATKKPLFQGDSEIDELFRIFRVLGTPTELEWNGV-ESLPDYKA 257
Query: 323 -FPQIRPIPLNRIF--KKETQETID-----LLYHIMKYDPNIRYSALQCMFNSTYFTDI 373
FP+ R L F KK + +D LL ++ YDP++R +A + + + YF ++
Sbjct: 258 TFPKWRENFLRDKFYDKKTGKHLLDDTAFSLLEGLLIYDPSLRLNAKKALVH-PYFDNM 315
>At5g63370 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 612
Score = 144 bits (362), Expect = 3e-34
Identities = 99/309 (32%), Positives = 171/309 (55%), Gaps = 43/309 (13%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKV-LQDRRFKN---------RELEIMKLISHPNLID 142
+ G++G+V++ + ++T E V +KK+ +++ RF+ RE+ I+ +HP +++
Sbjct: 303 INEGTYGIVYKARDEKTKEIVALKKIKMKEDRFEEEYGFPLTSLREINILLSCNHPAIVN 362
Query: 143 LKYYFLE-QSDQELYLNLIVDYMPMSL---YQRLKEFISLHQPMDRYEIKIYMFQLFKSL 198
+K + ++D ++Y+ +++++ L R KE P E+K M QL L
Sbjct: 363 VKEVVVGGKNDNDVYM--VMEHLEHDLRGVMDRRKE------PFSTSEVKCLMMQLLDGL 414
Query: 199 NYLHQVVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQL-KPNEPNVSYICSRYYRAPEL 257
YLH + HRD+KP N+L++ + LKICD G A+Q P +P + +++YR PEL
Sbjct: 415 KYLHTNW-IIHRDLKPSNLLMN-NCGELKICDFGMARQYGSPIKPYTQMVITQWYRPPEL 472
Query: 258 IFGATNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNEN 317
+ GA Y+T +D+WS GC+MAELL +P+FPG+S++DQL +I VLGTP E I +
Sbjct: 473 LLGAKEYSTAVDMWSVGCIMAELLSQKPLFPGKSELDQLQKIFAVLGTP-NEAIWPGFSS 531
Query: 318 Y--SEHKFPQIRPIPLNRIFKK-----------ETQETIDLLYHIMKYDPNIRYSALQCM 364
+ ++ KFP P N + KK ++ DLL ++ DP R + ++
Sbjct: 532 FPNAKAKFP---TQPYNMLRKKFPAISFVGGQILSERGFDLLNSLLTLDPEKRLT-VEDA 587
Query: 365 FNSTYFTDI 373
N +F ++
Sbjct: 588 LNHGWFHEV 596
>At4g01370 [T] KOG0660 Mitogen-activated protein kinase
Length = 376
Score = 144 bits (362), Expect = 3e-34
Identities = 82/274 (29%), Positives = 148/274 (53%), Gaps = 14/274 (5%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKV------LQDRRFKNRELEIMKLISHPNLIDLKYY 146
+G G++G+V ETGE+V IKK+ + D + RE++++K + H N+I +K
Sbjct: 49 IGRGAYGIVCAATNSETGEEVAIKKIGNAFDNIIDAKRTLREIKLLKHMDHENVIAVKD- 107
Query: 147 FLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVVN 206
++ +E + ++ + Y M L + I +QP+ + +++QL + L Y+H N
Sbjct: 108 IIKPPQRENFNDVYIVYELMDT--DLHQIIRSNQPLTDDHCRFFLYQLLRGLKYVHSA-N 164
Query: 207 VCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGATNYTT 266
V HRD+KP N+L++ + L K+ D G A+ + Y+ +R+YRAPEL+ + YT
Sbjct: 165 VLHRDLKPSNLLLNANCDL-KLGDFGLARTKSETDFMTEYVVTRWYRAPELLLNCSEYTA 223
Query: 267 KIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENYSEHKFPQI 326
IDIWS GC++ E + +P+FPG+ + QL I +++G+P + + + + Q+
Sbjct: 224 AIDIWSVGCILGETMTREPLFPGKDYVHQLRLITELIGSPDDSSLGFLRSDNARRYVRQL 283
Query: 327 RPIPLNRI---FKKETQETIDLLYHIMKYDPNIR 357
P F + +DLL ++ +DP+ R
Sbjct: 284 PQYPRQNFAARFPNMSAGAVDLLEKMLVFDPSRR 317
>At2g46070 [T] KOG0660 Mitogen-activated protein kinase
Length = 406
Score = 144 bits (362), Expect = 3e-34
Identities = 82/276 (29%), Positives = 147/276 (52%), Gaps = 14/276 (5%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKV------LQDRRFKNRELEIMKLISHPNLIDLKYY 146
+G G+ G+V TGE V IKK+ + D + RE+++++ + H N+I +K
Sbjct: 81 IGRGACGIVCAAVNSVTGEKVAIKKIGNAFDNIIDAKRTLREIKLLRHMDHENVITIKD- 139
Query: 147 FLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVVN 206
+ ++++ ++ + Y M L+ + +Q + + + ++QL + L Y+H N
Sbjct: 140 IVRPPQRDIFNDVYIVYELMDT--DLQRILRSNQTLTSDQCRFLVYQLLRGLKYVHSA-N 196
Query: 207 VCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGATNYTT 266
+ HRD++P N+L++ L KI D G A+ + Y+ +R+YRAPEL+ + YT
Sbjct: 197 ILHRDLRPSNVLLNSKNEL-KIGDFGLARTTSDTDFMTEYVVTRWYRAPELLLNCSEYTA 255
Query: 267 KIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENYSEHKFPQI 326
IDIWS GC++ E++ GQP+FPG+ + QL I +++G+P + + + + Q+
Sbjct: 256 AIDIWSVGCILGEIMTGQPLFPGKDYVHQLRLITELVGSPDNSSLGFLRSDNARRYVRQL 315
Query: 327 RPIPLNRI---FKKETQETIDLLYHIMKYDPNIRYS 359
P + F K IDLL ++ +DPN R S
Sbjct: 316 PRYPKQQFAARFPKMPTTAIDLLERMLVFDPNRRIS 351
>At1g10210 [T] KOG0660 Mitogen-activated protein kinase
Length = 370
Score = 144 bits (362), Expect = 3e-34
Identities = 97/288 (33%), Positives = 157/288 (53%), Gaps = 27/288 (9%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQ------DRRFKNRELEIMKLISHPNLIDLKYY 146
+G G++GVV + +T E V IKK+ D REL++++ + H N+I LK
Sbjct: 38 IGRGAYGVVCSSVNSDTNEKVAIKKIHNVYENRIDALRTLRELKLLRHLRHENVIALKDV 97
Query: 147 FL---EQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQ 203
+ + S +++YL + + M L+Q +K Q + + ++FQL + L Y+H
Sbjct: 98 MMPIHKMSFKDVYL--VYELMDTDLHQIIKS----SQVLSNDHCQYFLFQLLRGLKYIHS 151
Query: 204 VVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVS-YICSRYYRAPELIFGAT 262
N+ HRD+KP N+LV+ + L KICD G A+ ++ Y+ +R+YRAPEL+
Sbjct: 152 A-NILHRDLKPGNLLVNANCDL-KICDFGLARASNTKGQFMTEYVVTRWYRAPELLLCCD 209
Query: 263 NYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENYSEHK 322
NY T ID+WS GC+ AELL +PIF G ++QL I+ +LG+ REE +N +
Sbjct: 210 NYGTSIDVWSVGCIFAELLGRKPIFQGTECLNQLKLIVNILGS-QREEDLEFIDNPKAKR 268
Query: 323 FPQIRPIP------LNRIFKKETQETIDLLYHIMKYDPNIRYSALQCM 364
+ IR +P L+R++ IDLL ++ +DP+ R S + +
Sbjct: 269 Y--IRSLPYSPGMSLSRLYPGAHVLAIDLLQKMLVFDPSKRISVSEAL 314
>Hs7657498 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 419
Score = 143 bits (361), Expect = 4e-34
Identities = 87/281 (30%), Positives = 158/281 (55%), Gaps = 19/281 (6%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN-------RELEIMKLIS-HPNLIDLK 144
+G G+F V + + G K++ Q RF++ RE++ ++ ++ HPN++ L
Sbjct: 10 IGEGTFSEVMKMQSLRDGNYYACKQMKQ--RFESIEQVNNLREIQALRRLNPHPNILMLH 67
Query: 145 YYFLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQV 204
++ L L I + M M++Y+ ++ P+ +I YM+QL KSL+++H+
Sbjct: 68 EVVFDRKSGSLAL--ICELMDMNIYELIR---GRRYPLSEKKIMHYMYQLCKSLDHIHRN 122
Query: 205 VNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGATNY 264
+ HRD+KP+NIL+ D +LK+ D GS + + +P YI +R+YRAPE + Y
Sbjct: 123 -GIFHRDVKPENILIKQD--VLKLGDFGSCRSVYSKQPYTEYISTRWYRAPECLLTDGFY 179
Query: 265 TTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENYS-EHKF 323
T K+D+WSAGCV E+ QP+FPG +++DQ+ +I V+GTP ++ + ++ + F
Sbjct: 180 TYKMDLWSAGCVFYEIASLQPLFPGVNELDQISKIHDVIGTPAQKILTKFKQSRAMNFDF 239
Query: 324 PQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSALQCM 364
P + + + + + + LL+ ++ YDP+ R +A Q +
Sbjct: 240 PFKKGSGIPLLTTNLSPQCLSLLHAMVAYDPDERIAAHQAL 280
>Hs20128774 [T] KOG0660 Mitogen-activated protein kinase
Length = 364
Score = 143 bits (361), Expect = 4e-34
Identities = 92/288 (31%), Positives = 152/288 (51%), Gaps = 17/288 (5%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKV------LQDRRFKNRELEIMKLISHPNLIDLKYY 146
VG+G++G V + V +KK+ L R REL ++K + H N+I L
Sbjct: 30 VGSGAYGSVCSAYDARLRQKVAVKKLSRPFQSLIHARRTYRELRLLKHLKHENVIGLLDV 89
Query: 147 FLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVVN 206
F + E + + Y+ +L I Q + ++ ++QL + L Y+H
Sbjct: 90 FTPATSIEDFSEV---YLVTTLMGADLNNIVKCQALSDEHVQFLVYQLLRGLKYIHSA-G 145
Query: 207 VCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGATNYTT 266
+ HRD+KP N+ V+ D L +I D G A+Q +E Y+ +R+YRAPE++ +Y
Sbjct: 146 IIHRDLKPSNVAVNEDCEL-RILDFGLARQA--DEEMTGYVATRWYRAPEIMLNWMHYNQ 202
Query: 267 KIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENYSEHKFPQI 326
+DIWS GC+MAELL G+ +FPG IDQL I++V+GTP+ E + ++ ++ +
Sbjct: 203 TVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEVVGTPSPEVLAKISSEHARTYIQSL 262
Query: 327 RPIP---LNRIFKKETQETIDLLYHIMKYDPNIRYSALQCMFNSTYFT 371
P+P L+ IF+ IDLL ++ D + R SA + + ++ YF+
Sbjct: 263 PPMPQKDLSSIFRGANPLAIDLLGRMLVLDSDQRVSAAEALAHA-YFS 309
>SPBC11B10.09 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 297
Score = 142 bits (358), Expect = 9e-34
Identities = 85/284 (29%), Positives = 160/284 (55%), Gaps = 13/284 (4%)
Query: 91 EIVGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN------RELEIMKLISHPNLIDLK 144
E +G G++GVV++ + K +G V +KK+ + + RE+ ++K ++ N
Sbjct: 8 EKIGEGTYGVVYKARHKLSGRIVAMKKIRLEDESEGVPSTAIREISLLKEVNDENNRSNC 67
Query: 145 YYFLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQP-MDRYEIKIYMFQLFKSLNYLHQ 203
L+ E L L+ +++ M L + + +D ++ + +QL +N+ H
Sbjct: 68 VRLLDILHAESKLYLVFEFLDMDLKKYMDRISETGATSLDPRLVQKFTYQLVNGVNFCHS 127
Query: 204 VVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSY-ICSRYYRAPELIFGAT 262
+ HRD+KPQN+L+D + L K+ D G A+ N ++ I + +YRAPE++ G+
Sbjct: 128 R-RIIHRDLKPQNLLIDKEGNL-KLADFGLARSFGVPLRNYTHEIVTLWYRAPEVLLGSR 185
Query: 263 NYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTRE--EICSMNENYSE 320
+Y+T +DIWS GC+ AE++ P+FPG+S+ID++ +I +VLGTP E ++ ++Y +
Sbjct: 186 HYSTGVDIWSVGCIFAEMIRRSPLFPGDSEIDEIFKIFQVLGTPNEEVWPGVTLLQDY-K 244
Query: 321 HKFPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSALQCM 364
FP+ + + L+++ ++ I+LL ++ YDP R SA + +
Sbjct: 245 STFPRWKRMDLHKVVPNGEEDAIELLSAMLVYDPAHRISAKRAL 288
>7303051 [UT] KOG0662 Cyclin-dependent kinase CDK5
Length = 294
Score = 142 bits (358), Expect = 9e-34
Identities = 96/297 (32%), Positives = 163/297 (54%), Gaps = 23/297 (7%)
Query: 91 EIVGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN------RELEIMKLISHPNLIDLK 144
E +G G++G VF+ + ++T E V +K+V D + RE+ ++K + H N++ L
Sbjct: 8 EKIGEGTYGTVFKGRNRDTMEIVALKRVRLDEDDEGVPSSALREICLLKELKHKNIVRL- 66
Query: 145 YYFLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQV 204
++ + L L+ ++ L K F SL+ +D + +M QL + L + H
Sbjct: 67 ---IDVLHSDKKLTLVFEHCDQDLK---KYFDSLNGEIDMAVCRSFMLQLLRGLAFCHSH 120
Query: 205 VNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLK-PNEPNVSYICSRYYRAPELIFGATN 263
NV HRD+KPQN+L++ + L K+ D G A+ P + + + + +YR P+++FGA
Sbjct: 121 -NVLHRDLKPQNLLINKNGEL-KLADFGLARAFGIPVKCYSAEVVTLWYRPPDVLFGAKL 178
Query: 264 YTTKIDIWSAGCVMAELL-LGQPIFPGESKIDQLVEIIKVLGTPTREE---ICSMNENYS 319
YTT ID+WSAGC++AEL G+P+FPG +DQL++I +VLGTP + + +++ +
Sbjct: 179 YTTSIDMWSAGCILAELADAGRPLFPGSDVLDQLMKIFRVLGTPNEDSWPGVSHLSDYVA 238
Query: 320 EHKFPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSALQCMFNSTYFTDIVSN 376
FP I +++ + + DLL ++ PN R SA + YFTD S+
Sbjct: 239 LPSFPAI--TSWSQLVPRLNSKGRDLLQKLLICRPNQRISA-EAAMQHPYFTDSSSS 292
>Hs4502731 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 360
Score = 142 bits (357), Expect = 1e-33
Identities = 90/292 (30%), Positives = 155/292 (52%), Gaps = 23/292 (7%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN------RELEIMKLISHPNLIDLKYY 146
+G G++G+V+R + +T E V +KKV D+ RE+ ++ + HPN+++LK
Sbjct: 45 IGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLRLRHPNIVELKEV 104
Query: 147 FLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVVN 206
+ + ++L ++ Y L L+ ++ P ++K + Q+ + L YLH+
Sbjct: 105 VVGNHLESIFL--VMGYCEQDLASLLE---NMPTPFSEAQVKCIVLQVLRGLQYLHRNF- 158
Query: 207 VCHRDIKPQNILVDPDTLLLKICDLGSAKQLK-PNEPNVSYICSRYYRAPELIFGATNYT 265
+ HRD+K N+L+ D +K D G A+ P +P + + +YRAPEL+ G T T
Sbjct: 159 IIHRDLKVSNLLMT-DKGCVKTADFGLARAYGVPVKPMTPKVVTLWYRAPELLLGTTTQT 217
Query: 266 TKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNE-----NYSE 320
T ID+W+ GC++AELL +P+ PG S+I Q+ I+++LGTP+ ++ YS
Sbjct: 218 TSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLIVQLLGTPSENIWPGFSKLPLVGQYSL 277
Query: 321 HKFPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSALQCMFNSTYFTD 372
K P L F ++ + LL+ + YDP R +A C+ S+YF +
Sbjct: 278 RKQPYNN---LKHKFPWLSEAGLRLLHFLFMYDPKKRATAGDCL-ESSYFKE 325
>Hs16950647 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 314
Score = 142 bits (357), Expect = 1e-33
Identities = 90/292 (30%), Positives = 155/292 (52%), Gaps = 23/292 (7%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN------RELEIMKLISHPNLIDLKYY 146
+G G++G+V+R + +T E V +KKV D+ RE+ ++ + HPN+++LK
Sbjct: 16 IGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLRLRHPNIVELKEV 75
Query: 147 FLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVVN 206
+ + ++L ++ Y L L+ ++ P ++K + Q+ + L YLH+
Sbjct: 76 VVGNHLESIFL--VMGYCEQDLASLLE---NMPTPFSEAQVKCIVLQVLRGLQYLHRNF- 129
Query: 207 VCHRDIKPQNILVDPDTLLLKICDLGSAKQLK-PNEPNVSYICSRYYRAPELIFGATNYT 265
+ HRD+K N+L+ D +K D G A+ P +P + + +YRAPEL+ G T T
Sbjct: 130 IIHRDLKVSNLLMT-DKGCVKTADFGLARAYGVPVKPMTPKVVTLWYRAPELLLGTTTQT 188
Query: 266 TKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNE-----NYSE 320
T ID+W+ GC++AELL +P+ PG S+I Q+ I+++LGTP+ ++ YS
Sbjct: 189 TSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLIVQLLGTPSENIWPGFSKLPLVGQYSL 248
Query: 321 HKFPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSALQCMFNSTYFTD 372
K P L F ++ + LL+ + YDP R +A C+ S+YF +
Sbjct: 249 RKQPYNN---LKHKFPWLSEAGLRLLHFLFMYDPKKRATAGDCL-ESSYFKE 296
>YHR030c [T] KOG0660 Mitogen-activated protein kinase
Length = 484
Score = 141 bits (356), Expect = 2e-33
Identities = 97/286 (33%), Positives = 146/286 (50%), Gaps = 29/286 (10%)
Query: 93 VGNGSFGVVFRTKVKETGED--VVIKKV---LQDRRFKNRELEIMKLISHPN-------L 140
+G+G++G+V + E ED V IKKV R L +KL+ H L
Sbjct: 29 IGHGAYGIVCSARFAEAAEDTTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGHKNITCL 88
Query: 141 IDLKYYFL-EQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLN 199
D+ F + S LYL + M ++Q +K QP+ + + +Q+ L
Sbjct: 89 YDMDIVFYPDGSINGLYL--YEELMECDMHQIIKS----GQPLTDAHYQSFTYQILCGLK 142
Query: 200 YLHQVVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVS-----YICSRYYRA 254
Y+H +V HRD+KP N+LV+ D L KICD G A+ N S Y+ +R+YRA
Sbjct: 143 YIHSA-DVLHRDLKPGNLLVNADCQL-KICDFGLARGYSENPVENSQFLTEYVATRWYRA 200
Query: 255 PELIFGATNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTP---TREEI 311
PE++ YT ID+WSAGC++AE L G+PIF G+ ++QL +I++VLGTP T I
Sbjct: 201 PEIMLSYQGYTKAIDVWSAGCILAEFLGGKPIFKGKDYVNQLNQILQVLGTPPDETLRRI 260
Query: 312 CSMNENYSEHKFPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIR 357
S N H+ I +P ++ + +DLL ++ +DP R
Sbjct: 261 GSKNVQDYIHQLGFIPKVPFVNLYPNANSQALDLLEQMLAFDPQKR 306
>CE24971 [T] KOG0660 Mitogen-activated protein kinase
Length = 444
Score = 141 bits (356), Expect = 2e-33
Identities = 87/285 (30%), Positives = 151/285 (52%), Gaps = 20/285 (7%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKV--LQDRRFKNR---ELEIMKLISHPNLIDLKYYF 147
+G G++G+V T + V IKK+ + + F R E++I+ H N+I+++
Sbjct: 102 IGEGAYGMVASALDTITRDRVAIKKISPFEHQTFCQRTLREIKILNRFKHENIINIQEII 161
Query: 148 LEQSDQELYLNLIVD-YMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVVN 206
++ L IV M LY+ LK Q + + +++Q+ + L Y+H N
Sbjct: 162 RSETVDSLKDIYIVQCLMETDLYKLLKT-----QKLSNDHVCYFLYQILRGLKYIHSA-N 215
Query: 207 VCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVS----YICSRYYRAPELIFGAT 262
V HRD+KP N+L++ T LKICD G A+ P + Y+ +R+YRAPE++ +
Sbjct: 216 VLHRDLKPSNLLLNT-TCDLKICDFGLARVTDPQTDHTGFLTEYVATRWYRAPEIMLNSK 274
Query: 263 NYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEI-CSMNENYSEH 321
YT ID+WS GC++AE+L +P+FPG+ +DQL I+ V+G+P+ ++ C +N+ +
Sbjct: 275 GYTKSIDVWSVGCILAEMLSNRPLFPGKHYLDQLNLILAVVGSPSNADLQCIINDKARSY 334
Query: 322 --KFPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSALQCM 364
P P R++ +DLL ++ ++P+ R Q +
Sbjct: 335 LISLPHKPKQPWARLYPGADPRALDLLDKMLTFNPHNRIDIEQAL 379
>CE01583 [T] KOG0660 Mitogen-activated protein kinase
Length = 376
Score = 141 bits (356), Expect = 2e-33
Identities = 87/285 (30%), Positives = 151/285 (52%), Gaps = 20/285 (7%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKV--LQDRRFKNR---ELEIMKLISHPNLIDLKYYF 147
+G G++G+V T + V IKK+ + + F R E++I+ H N+I+++
Sbjct: 34 IGEGAYGMVASALDTITRDRVAIKKISPFEHQTFCQRTLREIKILNRFKHENIINIQEII 93
Query: 148 LEQSDQELYLNLIVD-YMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVVN 206
++ L IV M LY+ LK Q + + +++Q+ + L Y+H N
Sbjct: 94 RSETVDSLKDIYIVQCLMETDLYKLLKT-----QKLSNDHVCYFLYQILRGLKYIHSA-N 147
Query: 207 VCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVS----YICSRYYRAPELIFGAT 262
V HRD+KP N+L++ T LKICD G A+ P + Y+ +R+YRAPE++ +
Sbjct: 148 VLHRDLKPSNLLLNT-TCDLKICDFGLARVTDPQTDHTGFLTEYVATRWYRAPEIMLNSK 206
Query: 263 NYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEI-CSMNENYSEH 321
YT ID+WS GC++AE+L +P+FPG+ +DQL I+ V+G+P+ ++ C +N+ +
Sbjct: 207 GYTKSIDVWSVGCILAEMLSNRPLFPGKHYLDQLNLILAVVGSPSNADLQCIINDKARSY 266
Query: 322 --KFPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSALQCM 364
P P R++ +DLL ++ ++P+ R Q +
Sbjct: 267 LISLPHKPKQPWARLYPGADPRALDLLDKMLTFNPHNRIDIEQAL 311
>Hs4505649 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 523
Score = 141 bits (355), Expect = 2e-33
Identities = 89/318 (27%), Positives = 172/318 (53%), Gaps = 23/318 (7%)
Query: 91 EIVGNGSFGVVFRTKVKETGEDVVIKKVLQDRR-----FKNRELEIMKLISHPNLIDLKY 145
E +G G++ V++ + K T V +K++ + RE+ ++K + H N++ L
Sbjct: 196 EKLGEGTYATVYKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTL-- 253
Query: 146 YFLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVV 205
+ + +D+ L L+ +Y+ L Q + + ++ M + +K++++Q+ + L Y H+
Sbjct: 254 HDIVHTDKSL--TLVFEYLDKDLKQYMDDCGNI---MSMHNVKLFLYQILRGLAYCHRR- 307
Query: 206 NVCHRDIKPQNILVDPDTLLLKICDLGSAKQLK-PNEPNVSYICSRYYRAPELIFGATNY 264
V HRD+KPQN+L++ + LK+ D G A+ P + + + + +YR P+++ G++ Y
Sbjct: 308 KVLHRDLKPQNLLIN-EKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSSEY 366
Query: 265 TTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEI--CSMNENYSEHK 322
T+ID+W GC+ E+ G+P+FPG + D+L I ++LGTP++E S NE + +
Sbjct: 367 LTQIDMWGVGCIFFEMASGRPLFPGSTVEDELHLIFRLLGTPSQETWPGISSNEEFKNYN 426
Query: 323 FPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSALQCMFNSTYFTDIVSNTGSDSN 382
FP+ +P PL + E I+L+ ++Y+ R SA + M YF +
Sbjct: 427 FPKYKPEPLINHAPRLDSEGIELIRKFLQYESKKRVSAEEAM-KHVYFRSLGPRIH---- 481
Query: 383 LSLIDSLPLLHFEESELQ 400
+L +S+ + +E +LQ
Sbjct: 482 -ALPESVSIFSLKEIQLQ 498
>Hs7706059 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 455
Score = 140 bits (354), Expect = 3e-33
Identities = 88/289 (30%), Positives = 158/289 (54%), Gaps = 21/289 (7%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQDR------RFKNRELEIMKLISHPNLIDLKYY 146
VG GS+G V + K K TG+ V IK + +R + RE++ +K H NL++L
Sbjct: 10 VGEGSYGTVMKCKHKNTGQIVAIK-IFYERPEQSVNKIAMREIKFLKQFHHENLVNL--- 65
Query: 147 FLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVVN 206
+E Q+ ++L+ +++ ++ L+ + ++ ++ Y+FQ+ ++++YLH N
Sbjct: 66 -IEVFRQKKKIHLVFEFIDHTVLDELQHYC---HGLESKRLRKYLFQILRAIDYLHSN-N 120
Query: 207 VCHRDIKPQNILVDPDTLLLKICDLGSAKQLK-PNEPNVSYICSRYYRAPELIFGATNYT 265
+ HRDIKP+NILV + K+CD G A+ L P + Y+ +R+YRAPEL+ T+Y
Sbjct: 121 IIHRDIKPENILVSQSGIT-KLCDFGFARTLAAPGDIYTDYVATRWYRAPELVLKDTSYG 179
Query: 266 TKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLG--TPTREEICSMNENYSEHKF 323
+DIW+ GC++ E+ G P P S +D L +I+ +G +P + I S + ++
Sbjct: 180 KPVDIWALGCMIIEMATGNPYLPSSSDLDLLHKIVLKVGNLSPHLQNIFSKSPIFAGVVL 239
Query: 324 PQIR-PIPLNRIFKKETQETIDLLYHIMKYDPNIRYSALQCMFNSTYFT 371
PQ++ P + + K D+++ ++ DP R S+ + + YFT
Sbjct: 240 PQVQHPKNARKKYPKLNGLLADIVHACLQIDPADRISSSD-LLHHEYFT 287
>Hs4506085 [T] KOG0660 Mitogen-activated protein kinase
Length = 365
Score = 140 bits (353), Expect = 3e-33
Identities = 92/287 (32%), Positives = 150/287 (52%), Gaps = 21/287 (7%)
Query: 89 TPEIVGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN--------RELEIMKLISHPNL 140
+P VG+G++G V K +GE V IKK+ R F++ REL ++K + H N+
Sbjct: 27 SPTHVGSGAYGSVCSAIDKRSGEKVAIKKL--SRPFQSEIFAKRAYRELLLLKHMQHENV 84
Query: 141 IDLKYYFLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNY 200
I L F S + + Y+ M Q + I + +I+ ++Q+ K L Y
Sbjct: 85 IGLLDVFTPASSLRNFYDF---YLVMPFMQTDLQKI-MGMEFSEEKIQYLVYQMLKGLKY 140
Query: 201 LHQVVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFG 260
+H V HRD+KP N+ V+ D L KI D G A+ + Y+ +R+YRAPE+I
Sbjct: 141 IHSA-GVVHRDLKPGNLAVNEDCEL-KILDFGLARHA--DAEMTGYVVTRWYRAPEVILS 196
Query: 261 ATNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENYSE 320
+Y +DIWS GC+MAE+L G+ +F G+ +DQL +I+KV G P E + +N+ ++
Sbjct: 197 WMHYNQTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILKVTGVPGTEFVQKLNDKAAK 256
Query: 321 ---HKFPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSALQCM 364
PQ ++F + + + DLL +++ D + R +A Q +
Sbjct: 257 SYIQSLPQTPRKDFTQLFPRASPQAADLLEKMLELDVDKRLTAAQAL 303
>CE29478 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 437
Score = 140 bits (353), Expect = 3e-33
Identities = 92/288 (31%), Positives = 155/288 (52%), Gaps = 23/288 (7%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN--------RELEIMKLISHPNLIDLK 144
+G G+FGVV+ +G+ V +KK+ F+N RE++++ H N++ L
Sbjct: 49 IGYGAFGVVWSVTDPRSGKRVALKKM--PNVFQNLASCKRVFREIKMLSSFRHDNVLSL- 105
Query: 145 YYFLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQV 204
L+ ++ + L V + + L + I Q + +K++++Q+ + L YLH
Sbjct: 106 LDILQPANPSFFQELYV--LTELMQSDLHKIIVSPQALTPDHVKVFVYQILRGLKYLH-T 162
Query: 205 VNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEP-NVSY-ICSRYYRAPELIFGAT 262
N+ HRDIKP N+LV+ + +L KICD G A+ + N+++ + ++YYRAPEL+ GA
Sbjct: 163 ANILHRDIKPGNLLVNSNCIL-KICDFGLARTWDQRDRLNMTHEVVTQYYRAPELLMGAR 221
Query: 263 NYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENYSEHK 322
YT +DIWS GC+ AELL + +F I+QL II +LGTP++E + E H
Sbjct: 222 RYTGAVDIWSVGCIFAELLQRKILFQAAGPIEQLQMIIDLLGTPSQEAMKYACEGAKNHV 281
Query: 323 F-PQIRPIPLNRIFK-----KETQETIDLLYHIMKYDPNIRYSALQCM 364
+R R++K + E +DLL ++ +DP+ R S + +
Sbjct: 282 LRAGLRAPDTQRLYKIASPDDKNHEAVDLLQKLLHFDPDKRISVEEAL 329
>CE29477 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 462
Score = 140 bits (353), Expect = 3e-33
Identities = 92/288 (31%), Positives = 155/288 (52%), Gaps = 23/288 (7%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN--------RELEIMKLISHPNLIDLK 144
+G G+FGVV+ +G+ V +KK+ F+N RE++++ H N++ L
Sbjct: 74 IGYGAFGVVWSVTDPRSGKRVALKKM--PNVFQNLASCKRVFREIKMLSSFRHDNVLSL- 130
Query: 145 YYFLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQV 204
L+ ++ + L V + + L + I Q + +K++++Q+ + L YLH
Sbjct: 131 LDILQPANPSFFQELYV--LTELMQSDLHKIIVSPQALTPDHVKVFVYQILRGLKYLH-T 187
Query: 205 VNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEP-NVSY-ICSRYYRAPELIFGAT 262
N+ HRDIKP N+LV+ + +L KICD G A+ + N+++ + ++YYRAPEL+ GA
Sbjct: 188 ANILHRDIKPGNLLVNSNCIL-KICDFGLARTWDQRDRLNMTHEVVTQYYRAPELLMGAR 246
Query: 263 NYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENYSEHK 322
YT +DIWS GC+ AELL + +F I+QL II +LGTP++E + E H
Sbjct: 247 RYTGAVDIWSVGCIFAELLQRKILFQAAGPIEQLQMIIDLLGTPSQEAMKYACEGAKNHV 306
Query: 323 F-PQIRPIPLNRIFK-----KETQETIDLLYHIMKYDPNIRYSALQCM 364
+R R++K + E +DLL ++ +DP+ R S + +
Sbjct: 307 LRAGLRAPDTQRLYKIASPDDKNHEAVDLLQKLLHFDPDKRISVEEAL 354
>CE29476 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 634
Score = 140 bits (353), Expect = 3e-33
Identities = 92/288 (31%), Positives = 155/288 (52%), Gaps = 23/288 (7%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN--------RELEIMKLISHPNLIDLK 144
+G G+FGVV+ +G+ V +KK+ F+N RE++++ H N++ L
Sbjct: 246 IGYGAFGVVWSVTDPRSGKRVALKKM--PNVFQNLASCKRVFREIKMLSSFRHDNVLSL- 302
Query: 145 YYFLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQV 204
L+ ++ + L V + + L + I Q + +K++++Q+ + L YLH
Sbjct: 303 LDILQPANPSFFQELYV--LTELMQSDLHKIIVSPQALTPDHVKVFVYQILRGLKYLH-T 359
Query: 205 VNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEP-NVSY-ICSRYYRAPELIFGAT 262
N+ HRDIKP N+LV+ + +L KICD G A+ + N+++ + ++YYRAPEL+ GA
Sbjct: 360 ANILHRDIKPGNLLVNSNCIL-KICDFGLARTWDQRDRLNMTHEVVTQYYRAPELLMGAR 418
Query: 263 NYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENYSEHK 322
YT +DIWS GC+ AELL + +F I+QL II +LGTP++E + E H
Sbjct: 419 RYTGAVDIWSVGCIFAELLQRKILFQAAGPIEQLQMIIDLLGTPSQEAMKYACEGAKNHV 478
Query: 323 F-PQIRPIPLNRIFK-----KETQETIDLLYHIMKYDPNIRYSALQCM 364
+R R++K + E +DLL ++ +DP+ R S + +
Sbjct: 479 LRAGLRAPDTQRLYKIASPDDKNHEAVDLLQKLLHFDPDKRISVEEAL 526
>At3g05050 [D] KOG0600 Cdc2-related protein kinase
Length = 593
Score = 140 bits (352), Expect = 5e-33
Identities = 94/301 (31%), Positives = 153/301 (50%), Gaps = 21/301 (6%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQD------RRFKNRELEIMKLISHPNLIDLKYY 146
+G+G++ V++ K TG V +KKV D +F RE+ I++ + HPN+I L+
Sbjct: 144 IGSGTYSNVYKAKDSLTGNIVALKKVRCDVNERESLKFMAREILILRRLDHPNVIKLEGL 203
Query: 147 FLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVVN 206
+ LYL + YM L S ++K YM QL L + H
Sbjct: 204 VTSRMSSSLYL--VFRYMDHDLAGLAA---SPEIKFTEQQVKCYMKQLLSGLEHCHNR-G 257
Query: 207 VCHRDIKPQNILVDPDTLLLKICDLGSAK--QLKPNEPNVSYICSRYYRAPELIFGATNY 264
V HRDIK N+L+D D +L+I D G A + + + + +YR+PEL+ G Y
Sbjct: 258 VLHRDIKGSNLLID-DGGVLRIGDFGLATFFDASKRQEMTNRVVTLWYRSPELLHGVVEY 316
Query: 265 TTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENYSEHKFP 324
+ +D+WSAGC++AELL G+ I PG ++++QL I K+ G+P+ EE S HK
Sbjct: 317 SVGVDLWSAGCILAELLAGRAIMPGRNEVEQLHRIYKLCGSPS-EEYWKKIRLPSTHKHA 375
Query: 325 QIRPIP-----LNRIFKKETQETIDLLYHIMKYDPNIRYSALQCMFNSTYFTDIVSNTGS 379
+P+P + ++K + E + LL ++ DP R +A + + + T+ ++ S
Sbjct: 376 HHKPLPQYKRRIREVYKDFSPEALSLLDTLLALDPAERQTATDVLMSDFFTTEPLACQPS 435
Query: 380 D 380
D
Sbjct: 436 D 436
>CE02602_1 [T] KOG0660 Mitogen-activated protein kinase
Length = 342
Score = 140 bits (352), Expect = 5e-33
Identities = 96/305 (31%), Positives = 151/305 (49%), Gaps = 46/305 (15%)
Query: 91 EIVGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN--------RELEIMKLISHPNLID 142
E +G G+FGVV R + + V IKK+ R FKN RE+ I + +SH N+I+
Sbjct: 48 ENLGAGAFGVVCRAIDSKLNKQVAIKKIT--RVFKNQSTAKCALREIRITRELSHENIIN 105
Query: 143 LKYYFLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLH 202
+ +S + +++D M L LK +Q ++ + + +Q+ K L YLH
Sbjct: 106 STDVLMRESGSGQDIYIVMDLMETDLLSVLKS----NQTLNEKHFQYFFYQILKGLKYLH 161
Query: 203 QVVNVCHRDIKPQNILVDPDTLLLKICDLG------SAKQLKPNEPNV-------SYICS 249
+ HRD+KP N+L++ D L KI D G S K PN Y+ +
Sbjct: 162 SA-GIIHRDLKPANLLLNEDCSL-KIADFGMSRSGPSTKTTPNTSPNAHISGDLSQYVST 219
Query: 250 RYYRAPELIFGATNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTRE 309
+YRAPE++ Y T++DIWSAGC++AE+LL +PIF G Q+ +I+ LGTP +
Sbjct: 220 LWYRAPEILLSMGEYDTQVDIWSAGCILAEMLLLRPIFTGTDSYSQIQLLIEYLGTPDEQ 279
Query: 310 EICSMNENYSEHKFPQIR----------PIPLNRIFKKETQETIDLLYHIMKYDPNIRYS 359
I + K P IR P+P +F + E +++ +++ P R+S
Sbjct: 280 VIRRI-------KSPSIRDYISSFGPKTPLPFTAMFPNASIEARNIVSKMLQISPWKRFS 332
Query: 360 ALQCM 364
A Q +
Sbjct: 333 AEQLL 337
>CE26988 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 308
Score = 139 bits (351), Expect = 6e-33
Identities = 97/283 (34%), Positives = 144/283 (50%), Gaps = 42/283 (14%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN---------RELEIMKLISHPNLIDL 143
+G G F V+ + E+GE V IKK+ R + RE++++K I H N+I L
Sbjct: 11 LGEGQFANVYLAQDLESGECVAIKKIKLGSREEAKDGINRTAIREIKLLKEIHHDNIIGL 70
Query: 144 KYYFLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQ 203
+ ++ + L+ D+M L +K+ + P IK Q+ L +LH
Sbjct: 71 RDVIGHRTS----IQLVFDFMDTDLEHVIKDKEIILMPA---HIKNITMQMLLGLEFLH- 122
Query: 204 VVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGATN 263
V + HRD+KP N+L++ + + +R+YRAPEL+FGA +
Sbjct: 123 VHWILHRDLKPNNLLMN----------------------KMGRVVTRWYRAPELLFGARS 160
Query: 264 YTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNE--NYSEH 321
Y IDIWS GC++AELLL PIFPGES IDQLV+I +LG PT E +M E +Y
Sbjct: 161 YGVGIDIWSVGCIIAELLLRNPIFPGESDIDQLVKIFNILGCPTPETWPNMTEMNSYVII 220
Query: 322 KFPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSALQCM 364
K PQ + LN F Q+ +DL+ + +DP R + Q +
Sbjct: 221 K-PQTEYMALNYYFSAAPQDLLDLMAGMWTFDPIKRLTCTQSL 262
>At5g50860 [D] KOG0600 Cdc2-related protein kinase
Length = 580
Score = 139 bits (351), Expect = 6e-33
Identities = 97/297 (32%), Positives = 157/297 (52%), Gaps = 31/297 (10%)
Query: 91 EIVGNGSFGVVFRTKVKETGEDVVIKKVLQDR------RFKNRELEIMKLISHPNLIDLK 144
E +G G++ V++ K +G+ V +KKV D +F RE+ +++ ++HPN+I L+
Sbjct: 118 EKIGQGTYSNVYKAKDLLSGKIVALKKVRFDNLEAESVKFMAREILVLRRLNHPNVIKLQ 177
Query: 145 YYFLEQSDQELYLNLIVDYMPMSLY-----QRLKEFISLHQPMDRYEIKIYMFQLFKSLN 199
+ LYL + +YM L Q LK D ++K +M QL L
Sbjct: 178 GLVTSRVSCSLYL--VFEYMEHDLSGLAATQGLK--------FDLPQVKCFMKQLLSGLE 227
Query: 200 YLHQVVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNV--SYICSRYYRAPEL 257
+ H V HRDIK N+L+D D +L KI D G A P + S + + +YR PEL
Sbjct: 228 HCHSR-GVLHRDIKGSNLLIDNDGIL-KIADFGLATFYDPKQKQTMTSRVVTLWYRPPEL 285
Query: 258 IFGATNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTR---EEICSM 314
+ GAT+Y T +D+WSAGC+MAELL G+P+ PG ++++QL +I K+ G+P+ ++
Sbjct: 286 LLGATSYGTGVDLWSAGCIMAELLAGKPVMPGRTEVEQLHKIFKLCGSPSDSYWKKYRLP 345
Query: 315 NENYSEHKFPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSALQCMFNSTYFT 371
N + + P R + F T ++ L+ ++ DP R ++ + NS +FT
Sbjct: 346 NATLFKPQHPYKRCVA--EAFNGFTPSSVHLVETLLTIDPADRGTSTSAL-NSEFFT 399
>At1g07880 [T] KOG0660 Mitogen-activated protein kinase
Length = 363
Score = 139 bits (351), Expect = 6e-33
Identities = 83/276 (30%), Positives = 146/276 (52%), Gaps = 14/276 (5%)
Query: 91 EIVGNGSFGVVFRTKVKETGEDVVIKKVLQ------DRRFKNRELEIMKLISHPNLIDLK 144
E +G G++G+V ET E+V IKK+ D + RE++++ + H N+I +K
Sbjct: 37 EPIGRGAYGIVCCATNSETNEEVAIKKIANAFDNRVDAKRTLREIKLLSHMDHDNVIKIK 96
Query: 145 YYFLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQV 204
+E ++E + ++ + Y M L + I Q + + +++Q+ + L Y+H
Sbjct: 97 D-IIELPEKERFEDVYIVYELMDT--DLHQIIRSTQTLTDDHCQYFLYQILRGLKYIHSA 153
Query: 205 VNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGATNY 264
NV HRD+KP N++++ + L KICD G A+ E Y+ +R+YRAPEL+ ++ Y
Sbjct: 154 -NVLHRDLKPSNLVLNTNCDL-KICDFGLARTSNETEIMTEYVVTRWYRAPELLLNSSEY 211
Query: 265 TTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREE---ICSMNENYSEH 321
T IDIWS GC+ E+L + +FPG+ + QL I ++LG+P + + S N
Sbjct: 212 TGAIDIWSVGCIFMEILRRETLFPGKDYVQQLKLITELLGSPDDSDLDFLRSDNARKYVK 271
Query: 322 KFPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIR 357
+ P ++ F + +DL ++ +DP+ R
Sbjct: 272 QLPHVQKQSFREKFPNISPMALDLAEKMLVFDPSKR 307
>Hs16357494 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 775
Score = 139 bits (350), Expect = 8e-33
Identities = 84/282 (29%), Positives = 153/282 (53%), Gaps = 25/282 (8%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN------RELEIMKLISHPNLIDLKYY 146
+ G++GVV+R K K+T E V +K++ ++ + RE+ + HPN++ ++
Sbjct: 424 IEEGTYGVVYRAKDKKTDEIVALKRLKMEKENEGFPITSLREINTILKAQHPNIVTVREI 483
Query: 147 FLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVVN 206
+ + ++Y+ +++Y+ L ++ ++ QP E+K M QL + + +LH
Sbjct: 484 VVGSNMDKIYI--VMNYVEHDLKSLME---TMKQPFLPGEVKTLMIQLLRGVKHLHDNW- 537
Query: 207 VCHRDIKPQNILVDPDTLLLKICDLGSAKQL-KPNEPNVSYICSRYYRAPELIFGATNYT 265
+ HRD+K N+L+ +LK+ D G A++ P + + +++YRAPEL+ GA Y+
Sbjct: 538 ILHRDLKTSNLLLS-HAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYS 596
Query: 266 TKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNE-------NY 318
T +D+WS GC+ ELL +P+FPG S+IDQ+ ++ K LGTP+ + +E +
Sbjct: 597 TAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTF 656
Query: 319 SEHKFPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSA 360
SEH + +R R +++ DL+ + Y P R SA
Sbjct: 657 SEHPYNNLR----KRFGALLSEQGFDLMNKFLTYFPGRRISA 694
>Hs16357492 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 777
Score = 139 bits (350), Expect = 8e-33
Identities = 84/282 (29%), Positives = 153/282 (53%), Gaps = 25/282 (8%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN------RELEIMKLISHPNLIDLKYY 146
+ G++GVV+R K K+T E V +K++ ++ + RE+ + HPN++ ++
Sbjct: 426 IEEGTYGVVYRAKDKKTDEIVALKRLKMEKENEGFPITSLREINTILKAQHPNIVTVREI 485
Query: 147 FLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVVN 206
+ + ++Y+ +++Y+ L ++ ++ QP E+K M QL + + +LH
Sbjct: 486 VVGSNMDKIYI--VMNYVEHDLKSLME---TMKQPFLPGEVKTLMIQLLRGVKHLHDNW- 539
Query: 207 VCHRDIKPQNILVDPDTLLLKICDLGSAKQL-KPNEPNVSYICSRYYRAPELIFGATNYT 265
+ HRD+K N+L+ +LK+ D G A++ P + + +++YRAPEL+ GA Y+
Sbjct: 540 ILHRDLKTSNLLLS-HAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYS 598
Query: 266 TKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNE-------NY 318
T +D+WS GC+ ELL +P+FPG S+IDQ+ ++ K LGTP+ + +E +
Sbjct: 599 TAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTF 658
Query: 319 SEHKFPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSA 360
SEH + +R R +++ DL+ + Y P R SA
Sbjct: 659 SEHPYNNLR----KRFGALLSEQGFDLMNKFLTYFPGRRISA 696
>At1g53050 [D] KOG0600 Cdc2-related protein kinase
Length = 694
Score = 139 bits (349), Expect = 1e-32
Identities = 92/290 (31%), Positives = 155/290 (52%), Gaps = 20/290 (6%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQDR------RFKNRELEIMKLISHPNLIDLKYY 146
+G G++ V+R + + + V +KKV D RF RE++I++ + HPN+I L+
Sbjct: 140 IGQGTYSNVYRARDLDQKKIVALKKVRFDNLEPESVRFMAREIQILRRLDHPNIIKLEGL 199
Query: 147 FLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPM--DRYEIKIYMFQLFKSLNYLHQV 204
+ LYL + +YM L ++ H + ++K Y+ QL L++ H
Sbjct: 200 VTSRMSCSLYL--VFEYMEHDLAG-----LASHPAIKFSESQVKCYLQQLLHGLDHCHSR 252
Query: 205 VNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNE--PNVSYICSRYYRAPELIFGAT 262
V HRDIK N+L+D ++ +LKI D G A P + P S + + +YR PEL+ GAT
Sbjct: 253 -GVLHRDIKGSNLLID-NSGVLKIADFGLASFFDPRQTQPLTSRVVTLWYRPPELLLGAT 310
Query: 263 NYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREE-ICSMNENYSEH 321
Y +D+WSAGC++AEL G+PI PG ++++QL +I K+ G+PT + + S + +
Sbjct: 311 RYGAAVDLWSAGCILAELYAGKPIMPGRTEVEQLHKIFKLCGSPTEDYWVKSRLPHATIF 370
Query: 322 KFPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSALQCMFNSTYFT 371
K Q + FK+ Q + LL ++ +P+ R +A + + + T
Sbjct: 371 KPTQPYKRLVGETFKEFPQPALALLETLLSVNPDDRGTATAALKSEFFST 420
>Hs16357498 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 777
Score = 138 bits (348), Expect = 1e-32
Identities = 84/282 (29%), Positives = 152/282 (53%), Gaps = 25/282 (8%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN------RELEIMKLISHPNLIDLKYY 146
+ G++GVV+R K K+T E V +K++ ++ + RE+ + HPN++ ++
Sbjct: 426 IEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREI 485
Query: 147 FLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVVN 206
+ + ++Y+ +++Y+ L ++ ++ QP E+K M QL + + +LH
Sbjct: 486 VVGSNMDKIYI--VMNYVEHDLKSLME---TMKQPFLPGEVKTLMIQLLRGVKHLHDNW- 539
Query: 207 VCHRDIKPQNILVDPDTLLLKICDLGSAKQL-KPNEPNVSYICSRYYRAPELIFGATNYT 265
+ HRD+K N+L+ +LK+ D G A++ P + + +++YRAPEL+ GA Y+
Sbjct: 540 ILHRDLKTSNLLLS-HAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYS 598
Query: 266 TKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNE-------NY 318
T +D+WS GC+ ELL +P+FPG S+IDQ+ ++ K LGTP+ + +E +
Sbjct: 599 TAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTF 658
Query: 319 SEHKFPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSA 360
SEH + +R R + + DL+ + Y P R SA
Sbjct: 659 SEHPYNNLR----KRFGALLSDQGFDLMNKFLTYFPGRRISA 696
>Hs16357486 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 780
Score = 138 bits (348), Expect = 1e-32
Identities = 84/282 (29%), Positives = 152/282 (53%), Gaps = 25/282 (8%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN------RELEIMKLISHPNLIDLKYY 146
+ G++GVV+R K K+T E V +K++ ++ + RE+ + HPN++ ++
Sbjct: 429 IEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREI 488
Query: 147 FLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVVN 206
+ + ++Y+ +++Y+ L ++ ++ QP E+K M QL + + +LH
Sbjct: 489 VVGSNMDKIYI--VMNYVEHDLKSLME---TMKQPFLPGEVKTLMIQLLRGVKHLHDNW- 542
Query: 207 VCHRDIKPQNILVDPDTLLLKICDLGSAKQL-KPNEPNVSYICSRYYRAPELIFGATNYT 265
+ HRD+K N+L+ +LK+ D G A++ P + + +++YRAPEL+ GA Y+
Sbjct: 543 ILHRDLKTSNLLLS-HAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYS 601
Query: 266 TKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNE-------NY 318
T +D+WS GC+ ELL +P+FPG S+IDQ+ ++ K LGTP+ + +E +
Sbjct: 602 TAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTF 661
Query: 319 SEHKFPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSA 360
SEH + +R R + + DL+ + Y P R SA
Sbjct: 662 SEHPYNNLR----KRFGALLSDQGFDLMNKFLTYFPGRRISA 699
>Hs16357484 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 767
Score = 138 bits (348), Expect = 1e-32
Identities = 84/282 (29%), Positives = 152/282 (53%), Gaps = 25/282 (8%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN------RELEIMKLISHPNLIDLKYY 146
+ G++GVV+R K K+T E V +K++ ++ + RE+ + HPN++ ++
Sbjct: 416 IEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREI 475
Query: 147 FLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVVN 206
+ + ++Y+ +++Y+ L ++ ++ QP E+K M QL + + +LH
Sbjct: 476 VVGSNMDKIYI--VMNYVEHDLKSLME---TMKQPFLPGEVKTLMIQLLRGVKHLHDNW- 529
Query: 207 VCHRDIKPQNILVDPDTLLLKICDLGSAKQL-KPNEPNVSYICSRYYRAPELIFGATNYT 265
+ HRD+K N+L+ +LK+ D G A++ P + + +++YRAPEL+ GA Y+
Sbjct: 530 ILHRDLKTSNLLLS-HAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYS 588
Query: 266 TKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNE-------NY 318
T +D+WS GC+ ELL +P+FPG S+IDQ+ ++ K LGTP+ + +E +
Sbjct: 589 TAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTF 648
Query: 319 SEHKFPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSA 360
SEH + +R R + + DL+ + Y P R SA
Sbjct: 649 SEHPYNNLR----KRFGALLSDQGFDLMNKFLTYFPGRRISA 686
>Hs16357482 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 776
Score = 138 bits (348), Expect = 1e-32
Identities = 84/282 (29%), Positives = 152/282 (53%), Gaps = 25/282 (8%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN------RELEIMKLISHPNLIDLKYY 146
+ G++GVV+R K K+T E V +K++ ++ + RE+ + HPN++ ++
Sbjct: 425 IEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREI 484
Query: 147 FLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVVN 206
+ + ++Y+ +++Y+ L ++ ++ QP E+K M QL + + +LH
Sbjct: 485 VVGSNMDKIYI--VMNYVEHDLKSLME---TMKQPFLPGEVKTLMIQLLRGVKHLHDNW- 538
Query: 207 VCHRDIKPQNILVDPDTLLLKICDLGSAKQL-KPNEPNVSYICSRYYRAPELIFGATNYT 265
+ HRD+K N+L+ +LK+ D G A++ P + + +++YRAPEL+ GA Y+
Sbjct: 539 ILHRDLKTSNLLLS-HAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYS 597
Query: 266 TKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNE-------NY 318
T +D+WS GC+ ELL +P+FPG S+IDQ+ ++ K LGTP+ + +E +
Sbjct: 598 TAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTF 657
Query: 319 SEHKFPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSA 360
SEH + +R R + + DL+ + Y P R SA
Sbjct: 658 SEHPYNNLR----KRFGALLSDQGFDLMNKFLTYFPGRRISA 695
>Hs16357480 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 397
Score = 138 bits (348), Expect = 1e-32
Identities = 84/282 (29%), Positives = 152/282 (53%), Gaps = 25/282 (8%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN------RELEIMKLISHPNLIDLKYY 146
+ G++GVV+R K K+T E V +K++ ++ + RE+ + HPN++ ++
Sbjct: 46 IEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREI 105
Query: 147 FLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVVN 206
+ + ++Y+ +++Y+ L ++ ++ QP E+K M QL + + +LH
Sbjct: 106 VVGSNMDKIYI--VMNYVEHDLKSLME---TMKQPFLPGEVKTLMIQLLRGVKHLHDNW- 159
Query: 207 VCHRDIKPQNILVDPDTLLLKICDLGSAKQL-KPNEPNVSYICSRYYRAPELIFGATNYT 265
+ HRD+K N+L+ +LK+ D G A++ P + + +++YRAPEL+ GA Y+
Sbjct: 160 ILHRDLKTSNLLLS-HAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYS 218
Query: 266 TKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNE-------NY 318
T +D+WS GC+ ELL +P+FPG S+IDQ+ ++ K LGTP+ + +E +
Sbjct: 219 TAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTF 278
Query: 319 SEHKFPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSA 360
SEH + +R R + + DL+ + Y P R SA
Sbjct: 279 SEHPYNNLR----KRFGALLSDQGFDLMNKFLTYFPGRRISA 316
>CE09532 [G] KOG0658 Glycogen synthase kinase-3
Length = 440
Score = 138 bits (348), Expect = 1e-32
Identities = 84/274 (30%), Positives = 140/274 (50%), Gaps = 12/274 (4%)
Query: 96 GSFGVVFRTKVKETGED-VVIKKVLQDRRFKNRELEIM---KLISHPNLIDLKYYFLEQS 151
G F V++ ++E E + IKK ++ +N E + + H N+I + + F
Sbjct: 32 GVFSNVYKGILREPYEKKIAIKKSWPEKGERNFEFIFLTGRERAKHKNVIHMIFAFSHSY 91
Query: 152 DQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVVNVCHRD 211
D ++ + + D+MP +L + ++ Q + +I++Y +Q+F L YL + V HRD
Sbjct: 92 DTKVCESYVFDFMPNTLAEVIR------QKLTDLDIRLYTWQIFSGLKYLEEH-KVVHRD 144
Query: 212 IKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGATNYTTKIDIW 271
+KP NILVD DT LKI D GSAK + + N Y +R+YR PEL+ A Y + +D+W
Sbjct: 145 LKPVNILVDHDTAFLKISDFGSAKIIVKGKANNFYQVTRFYRPPELLMKAMEYNSTVDVW 204
Query: 272 SAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSM-NENYSEHKFPQIRPIP 330
SAGC+MAE++ +FPG QL + G P ++I +M E + + +
Sbjct: 205 SAGCIMAEMVKRHVVFPGRDSAHQLKLYCRCFGAPNEQDISAMKGEKLEKEYWKFTKGFG 264
Query: 331 LNRIFKKETQETIDLLYHIMKYDPNIRYSALQCM 364
L R+ + + + + I+ Y P R Q +
Sbjct: 265 LQRLVNDISPDQLQFIKRILVYAPEKRLRGKQLL 298
>CE05866 [G] KOG0658 Glycogen synthase kinase-3
Length = 399
Score = 138 bits (348), Expect = 1e-32
Identities = 85/281 (30%), Positives = 143/281 (50%), Gaps = 12/281 (4%)
Query: 96 GSFGVVFRTKVKETGE-DVVIKKVLQDRRFKNRELEIM---KLISHPNLIDLKYYFLEQS 151
G F V++ ++E E ++ IKK ++ +N E + + H N+I + + F
Sbjct: 32 GVFSNVYKGILREPHEKNIAIKKSWPEKGERNFEFIFLTGRERTKHKNVIHMIFAFSHSY 91
Query: 152 DQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVVNVCHRD 211
++ + + DYMP +L + ++ Q + +I++Y +Q+F L YL + V HRD
Sbjct: 92 GTKVCESYVFDYMPNTLAEVIR------QKLTDLDIRLYTWQIFSGLKYLEEH-RVVHRD 144
Query: 212 IKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGATNYTTKIDIW 271
+KP NILVD DT LKI D GS K + + N Y +R+YR PEL+ A Y +D+W
Sbjct: 145 LKPVNILVDHDTGFLKISDFGSVKIIVKGKANNHYQVTRFYRPPELLQKAMEYNCTVDVW 204
Query: 272 SAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSM-NENYSEHKFPQIRPIP 330
SAGC+MAE++ + +FPG Q+ + G PT ++I +M E + +
Sbjct: 205 SAGCIMAEMVKRRVVFPGRDSAQQMKLYCRCFGVPTEQDILAMKGERLENELWKFTKGFG 264
Query: 331 LNRIFKKETQETIDLLYHIMKYDPNIRYSALQCMFNSTYFT 371
L R+ + T + + + I+ Y P R Q + + + T
Sbjct: 265 LQRLVTEITPDQLQFIKRILVYTPEKRLHGKQLLQDDFFQT 305
>At1g54610 [D] KOG0600 Cdc2-related protein kinase
Length = 572
Score = 138 bits (348), Expect = 1e-32
Identities = 83/225 (36%), Positives = 125/225 (54%), Gaps = 15/225 (6%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQDR------RFKNRELEIMKLISHPNLIDLKYY 146
+G G++ V++ K TG+ V +KKV D +F RE+ +++ + HPN++ L+
Sbjct: 124 IGQGTYSNVYKAKDMLTGKIVALKKVRFDNLEPESVKFMAREILVLRRLDHPNVVKLEGL 183
Query: 147 FLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVVN 206
+ LYL + YM L + E+K M QL L + H
Sbjct: 184 VTSRMSCSLYL--VFQYMDHDLAGLASSPVV---KFSESEVKCLMRQLISGLEHCHSR-G 237
Query: 207 VCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNE--PNVSYICSRYYRAPELIFGATNY 264
V HRDIK N+L+D D +LKI D G A PN P S + + +YRAPEL+ GAT+Y
Sbjct: 238 VLHRDIKGSNLLID-DGGVLKIADFGLATIFDPNHKRPMTSRVVTLWYRAPELLLGATDY 296
Query: 265 TTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTRE 309
ID+WSAGC++AELL G+PI PG ++++QL +I K+ G+P+ +
Sbjct: 297 GVGIDLWSAGCILAELLAGRPIMPGRTEVEQLHKIYKLCGSPSED 341
>At5g39420 [D] KOG0600 Cdc2-related protein kinase
Length = 576
Score = 137 bits (346), Expect = 2e-32
Identities = 85/225 (37%), Positives = 131/225 (57%), Gaps = 17/225 (7%)
Query: 91 EIVGNGSFGVVFRTKVKETGEDVVIKKVLQDR------RFKNRELEIMKLISHPNLIDLK 144
E +G G++ VFR + ETG+ V +KKV D RF RE+ I++ ++HPN++ L+
Sbjct: 109 EKIGQGTYSSVFRAREVETGKMVALKKVKFDNLQPESIRFMAREILILRKLNHPNIMKLE 168
Query: 145 YYFLEQSDQELYLNLIVDYMPMSLYQRLKE-FISLHQPMDRYEIKIYMFQLFKSLNYLHQ 203
++ +YL + +YM L I +P +IK YM QL L + H
Sbjct: 169 GIVTSRASSSIYL--VFEYMEHDLAGLSSNPDIRFTEP----QIKCYMKQLLWGLEHCH- 221
Query: 204 VVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPN--VSYICSRYYRAPELIFGA 261
+ V HRDIK NILV+ + +LK+ D G A + P+ N S + + +YRAPEL+ G+
Sbjct: 222 MRGVIHRDIKASNILVN-NKGVLKLGDFGLANVVTPSNKNQLTSRVVTLWYRAPELLMGS 280
Query: 262 TNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTP 306
T+Y +D+WS GCV AE+L+G+PI G ++I+QL +I K+ G+P
Sbjct: 281 TSYGVSVDLWSVGCVFAEILMGKPILKGRTEIEQLHKIYKLCGSP 325
>7297680 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 297
Score = 137 bits (346), Expect = 2e-32
Identities = 85/279 (30%), Positives = 156/279 (55%), Gaps = 17/279 (6%)
Query: 91 EIVGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN------RELEIMKLISHPNLIDLK 144
E +G G++GVV++ + + TG+ V +KK+ + + RE+ ++K + H N++ L+
Sbjct: 8 EKIGEGTYGVVYKGRNRLTGQIVAMKKIRLESDDEGVPSTAIREISLLKELKHENIVCLE 67
Query: 145 YYFLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQV 204
+E++ + LI +++ M L ++ + + + + M+ ++ Y++Q+ ++ + H+
Sbjct: 68 DVLMEENR----IYLIFEFLSMDL-KKYMDSLPVDKHMESELVRSYLYQITSAILFCHRR 122
Query: 205 VNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLK-PNEPNVSYICSRYYRAPELIFGATN 263
V HRD+KPQN+L+D L+ K+ D G + P I + +YRAPE++ G+
Sbjct: 123 -RVLHRDLKPQNLLIDKSGLI-KVADFGLGRSFGIPVRIYTHEIVTLWYRAPEVLLGSPR 180
Query: 264 YTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENYSEHK- 322
Y+ +DIWS GC+ AE+ +P+F G+S+IDQL + ++L TPT E+I + ++K
Sbjct: 181 YSCPVDIWSIGCIFAEMATRKPLFQGDSEIDQLFRMFRILKTPT-EDIWPGVTSLPDYKN 239
Query: 323 -FPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSA 360
FP L K IDL+ ++ YDP R SA
Sbjct: 240 TFPCWSTNQLTNQLKNLDANGIDLIQKMLIYDPVHRISA 278
>Hs21237745 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 424
Score = 137 bits (345), Expect = 3e-32
Identities = 95/292 (32%), Positives = 150/292 (50%), Gaps = 37/292 (12%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN--------RELEIMKLISHPNLIDLK 144
+G+G+ G+V G +V +KK+ R F+N REL ++K ++H N+I L
Sbjct: 32 IGSGAQGIVCAAFDTVLGINVAVKKL--SRPFQNQTHAKRAYRELVLLKCVNHKNIISLL 89
Query: 145 YYFLEQSDQELYLN--LIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLH 202
F Q E + + L+++ M +L Q +H +D + ++Q+ + +LH
Sbjct: 90 NVFTPQKTLEEFQDVYLVMELMDANLCQ------VIHMELDHERMSYLLYQMLCGIKHLH 143
Query: 203 QVVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGAT 262
+ HRD+KP NI+V D L KI D G A+ N Y+ +RYYRAPE+I G
Sbjct: 144 SA-GIIHRDLKPSNIVVKSDCTL-KILDFGLARTACTNFMMTPYVVTRYYRAPEVILGM- 200
Query: 263 NYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMN---ENYS 319
Y +DIWS GC+MAE++L + +FPG IDQ ++I+ LGTP+ E + + NY
Sbjct: 201 GYKENVDIWSVGCIMAEMVLHKVLFPGRDYIDQWNKVIEQLGTPSAEFMKKLQPTVRNYV 260
Query: 320 EHKFPQIRPIPLNRIF------------KKETQETIDLLYHIMKYDPNIRYS 359
E++ P+ I +F K +T + DLL ++ DP+ R S
Sbjct: 261 ENR-PKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSKMLVIDPDKRIS 311
>Hs21237742 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 382
Score = 137 bits (345), Expect = 3e-32
Identities = 95/292 (32%), Positives = 150/292 (50%), Gaps = 37/292 (12%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN--------RELEIMKLISHPNLIDLK 144
+G+G+ G+V G +V +KK+ R F+N REL ++K ++H N+I L
Sbjct: 32 IGSGAQGIVCAAFDTVLGINVAVKKL--SRPFQNQTHAKRAYRELVLLKCVNHKNIISLL 89
Query: 145 YYFLEQSDQELYLN--LIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLH 202
F Q E + + L+++ M +L Q +H +D + ++Q+ + +LH
Sbjct: 90 NVFTPQKTLEEFQDVYLVMELMDANLCQ------VIHMELDHERMSYLLYQMLCGIKHLH 143
Query: 203 QVVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGAT 262
+ HRD+KP NI+V D L KI D G A+ N Y+ +RYYRAPE+I G
Sbjct: 144 SA-GIIHRDLKPSNIVVKSDCTL-KILDFGLARTACTNFMMTPYVVTRYYRAPEVILGM- 200
Query: 263 NYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMN---ENYS 319
Y +DIWS GC+MAE++L + +FPG IDQ ++I+ LGTP+ E + + NY
Sbjct: 201 GYKENVDIWSVGCIMAEMVLHKVLFPGRDYIDQWNKVIEQLGTPSAEFMKKLQPTVRNYV 260
Query: 320 EHKFPQIRPIPLNRIF------------KKETQETIDLLYHIMKYDPNIRYS 359
E++ P+ I +F K +T + DLL ++ DP+ R S
Sbjct: 261 ENR-PKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSKMLVIDPDKRIS 311
>Hs16357496 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 439
Score = 137 bits (345), Expect = 3e-32
Identities = 84/282 (29%), Positives = 152/282 (53%), Gaps = 25/282 (8%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN------RELEIMKLISHPNLIDLKYY 146
+ G++GVV+R K K+T E V +K++ ++ + RE+ + HPN++ ++
Sbjct: 88 IEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREI 147
Query: 147 FLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVVN 206
+ + ++Y+ +++Y+ L ++ ++ QP E+K M QL + + +LH
Sbjct: 148 VVGSNMDKIYI--VMNYVEHDLKSLME---TMKQPFLPGEVKTLMIQLLRGVKHLHDNW- 201
Query: 207 VCHRDIKPQNILVDPDTLLLKICDLGSAKQL-KPNEPNVSYICSRYYRAPELIFGATNYT 265
+ HRD+K N+L+ +LK+ D G A++ P + + + +YRAPEL+ GA Y+
Sbjct: 202 ILHRDLKTSNLLLS-HAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYS 260
Query: 266 TKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNE-------NY 318
T +D+WS GC+ ELL +P+FPG+S+IDQ+ ++ K LGTP+ + +E +
Sbjct: 261 TAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKMTF 320
Query: 319 SEHKFPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSA 360
SEH + +R R + + DL+ + Y P R SA
Sbjct: 321 SEHPYNNLR----KRFGALLSDQGFDLMNKFLTYFPGRRISA 358
>Hs16332372 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 771
Score = 137 bits (345), Expect = 3e-32
Identities = 84/282 (29%), Positives = 152/282 (53%), Gaps = 25/282 (8%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN------RELEIMKLISHPNLIDLKYY 146
+ G++GVV+R K K+T E V +K++ ++ + RE+ + HPN++ ++
Sbjct: 420 IEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREI 479
Query: 147 FLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVVN 206
+ + ++Y+ +++Y+ L ++ ++ QP E+K M QL + + +LH
Sbjct: 480 VVGSNMDKIYI--VMNYVEHDLKSLME---TMKQPFLPGEVKTLMIQLLRGVKHLHDNW- 533
Query: 207 VCHRDIKPQNILVDPDTLLLKICDLGSAKQL-KPNEPNVSYICSRYYRAPELIFGATNYT 265
+ HRD+K N+L+ +LK+ D G A++ P + + + +YRAPEL+ GA Y+
Sbjct: 534 ILHRDLKTSNLLLS-HAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYS 592
Query: 266 TKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNE-------NY 318
T +D+WS GC+ ELL +P+FPG+S+IDQ+ ++ K LGTP+ + +E +
Sbjct: 593 TAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKMTF 652
Query: 319 SEHKFPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSA 360
SEH + +R R + + DL+ + Y P R SA
Sbjct: 653 SEHPYNNLR----KRFGALLSDQGFDLMNKFLTYFPGRRISA 690
>Hs16332370 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 780
Score = 137 bits (345), Expect = 3e-32
Identities = 84/282 (29%), Positives = 152/282 (53%), Gaps = 25/282 (8%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN------RELEIMKLISHPNLIDLKYY 146
+ G++GVV+R K K+T E V +K++ ++ + RE+ + HPN++ ++
Sbjct: 429 IEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREI 488
Query: 147 FLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVVN 206
+ + ++Y+ +++Y+ L ++ ++ QP E+K M QL + + +LH
Sbjct: 489 VVGSNMDKIYI--VMNYVEHDLKSLME---TMKQPFLPGEVKTLMIQLLRGVKHLHDNW- 542
Query: 207 VCHRDIKPQNILVDPDTLLLKICDLGSAKQL-KPNEPNVSYICSRYYRAPELIFGATNYT 265
+ HRD+K N+L+ +LK+ D G A++ P + + + +YRAPEL+ GA Y+
Sbjct: 543 ILHRDLKTSNLLLS-HAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYS 601
Query: 266 TKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNE-------NY 318
T +D+WS GC+ ELL +P+FPG+S+IDQ+ ++ K LGTP+ + +E +
Sbjct: 602 TAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKMTF 661
Query: 319 SEHKFPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSA 360
SEH + +R R + + DL+ + Y P R SA
Sbjct: 662 SEHPYNNLR----KRFGALLSDQGFDLMNKFLTYFPGRRISA 699
>Hs16332368 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 461
Score = 137 bits (345), Expect = 3e-32
Identities = 84/282 (29%), Positives = 152/282 (53%), Gaps = 25/282 (8%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN------RELEIMKLISHPNLIDLKYY 146
+ G++GVV+R K K+T E V +K++ ++ + RE+ + HPN++ ++
Sbjct: 110 IEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREI 169
Query: 147 FLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVVN 206
+ + ++Y+ +++Y+ L ++ ++ QP E+K M QL + + +LH
Sbjct: 170 VVGSNMDKIYI--VMNYVEHDLKSLME---TMKQPFLPGEVKTLMIQLLRGVKHLHDNW- 223
Query: 207 VCHRDIKPQNILVDPDTLLLKICDLGSAKQL-KPNEPNVSYICSRYYRAPELIFGATNYT 265
+ HRD+K N+L+ +LK+ D G A++ P + + + +YRAPEL+ GA Y+
Sbjct: 224 ILHRDLKTSNLLLS-HAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYS 282
Query: 266 TKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNE-------NY 318
T +D+WS GC+ ELL +P+FPG+S+IDQ+ ++ K LGTP+ + +E +
Sbjct: 283 TAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKMTF 342
Query: 319 SEHKFPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSA 360
SEH + +R R + + DL+ + Y P R SA
Sbjct: 343 SEHPYNNLR----KRFGALLSDQGFDLMNKFLTYFPGRRISA 380
>Hs16332366 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 565
Score = 137 bits (345), Expect = 3e-32
Identities = 84/282 (29%), Positives = 152/282 (53%), Gaps = 25/282 (8%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN------RELEIMKLISHPNLIDLKYY 146
+ G++GVV+R K K+T E V +K++ ++ + RE+ + HPN++ ++
Sbjct: 214 IEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREI 273
Query: 147 FLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVVN 206
+ + ++Y+ +++Y+ L ++ ++ QP E+K M QL + + +LH
Sbjct: 274 VVGSNMDKIYI--VMNYVEHDLKSLME---TMKQPFLPGEVKTLMIQLLRGVKHLHDNW- 327
Query: 207 VCHRDIKPQNILVDPDTLLLKICDLGSAKQL-KPNEPNVSYICSRYYRAPELIFGATNYT 265
+ HRD+K N+L+ +LK+ D G A++ P + + + +YRAPEL+ GA Y+
Sbjct: 328 ILHRDLKTSNLLLS-HAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYS 386
Query: 266 TKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNE-------NY 318
T +D+WS GC+ ELL +P+FPG+S+IDQ+ ++ K LGTP+ + +E +
Sbjct: 387 TAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKMTF 446
Query: 319 SEHKFPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSA 360
SEH + +R R + + DL+ + Y P R SA
Sbjct: 447 SEHPYNNLR----KRFGALLSDQGFDLMNKFLTYFPGRRISA 484
>Hs16332364 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 748
Score = 137 bits (345), Expect = 3e-32
Identities = 84/282 (29%), Positives = 152/282 (53%), Gaps = 25/282 (8%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN------RELEIMKLISHPNLIDLKYY 146
+ G++GVV+R K K+T E V +K++ ++ + RE+ + HPN++ ++
Sbjct: 397 IEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREI 456
Query: 147 FLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVVN 206
+ + ++Y+ +++Y+ L ++ ++ QP E+K M QL + + +LH
Sbjct: 457 VVGSNMDKIYI--VMNYVEHDLKSLME---TMKQPFLPGEVKTLMIQLLRGVKHLHDNW- 510
Query: 207 VCHRDIKPQNILVDPDTLLLKICDLGSAKQL-KPNEPNVSYICSRYYRAPELIFGATNYT 265
+ HRD+K N+L+ +LK+ D G A++ P + + + +YRAPEL+ GA Y+
Sbjct: 511 ILHRDLKTSNLLLS-HAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYS 569
Query: 266 TKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNE-------NY 318
T +D+WS GC+ ELL +P+FPG+S+IDQ+ ++ K LGTP+ + +E +
Sbjct: 570 TAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKMTF 629
Query: 319 SEHKFPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSA 360
SEH + +R R + + DL+ + Y P R SA
Sbjct: 630 SEHPYNNLR----KRFGALLSDQGFDLMNKFLTYFPGRRISA 667
>Hs16332362 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 737
Score = 137 bits (345), Expect = 3e-32
Identities = 84/282 (29%), Positives = 152/282 (53%), Gaps = 25/282 (8%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN------RELEIMKLISHPNLIDLKYY 146
+ G++GVV+R K K+T E V +K++ ++ + RE+ + HPN++ ++
Sbjct: 386 IEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREI 445
Query: 147 FLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVVN 206
+ + ++Y+ +++Y+ L ++ ++ QP E+K M QL + + +LH
Sbjct: 446 VVGSNMDKIYI--VMNYVEHDLKSLME---TMKQPFLPGEVKTLMIQLLRGVKHLHDNW- 499
Query: 207 VCHRDIKPQNILVDPDTLLLKICDLGSAKQL-KPNEPNVSYICSRYYRAPELIFGATNYT 265
+ HRD+K N+L+ +LK+ D G A++ P + + + +YRAPEL+ GA Y+
Sbjct: 500 ILHRDLKTSNLLLS-HAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYS 558
Query: 266 TKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNE-------NY 318
T +D+WS GC+ ELL +P+FPG+S+IDQ+ ++ K LGTP+ + +E +
Sbjct: 559 TAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKMTF 618
Query: 319 SEHKFPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSA 360
SEH + +R R + + DL+ + Y P R SA
Sbjct: 619 SEHPYNNLR----KRFGALLSDQGFDLMNKFLTYFPGRRISA 656
>Hs16332360 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 526
Score = 137 bits (345), Expect = 3e-32
Identities = 84/282 (29%), Positives = 152/282 (53%), Gaps = 25/282 (8%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN------RELEIMKLISHPNLIDLKYY 146
+ G++GVV+R K K+T E V +K++ ++ + RE+ + HPN++ ++
Sbjct: 175 IEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREI 234
Query: 147 FLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVVN 206
+ + ++Y+ +++Y+ L ++ ++ QP E+K M QL + + +LH
Sbjct: 235 VVGSNMDKIYI--VMNYVEHDLKSLME---TMKQPFLPGEVKTLMIQLLRGVKHLHDNW- 288
Query: 207 VCHRDIKPQNILVDPDTLLLKICDLGSAKQL-KPNEPNVSYICSRYYRAPELIFGATNYT 265
+ HRD+K N+L+ +LK+ D G A++ P + + + +YRAPEL+ GA Y+
Sbjct: 289 ILHRDLKTSNLLLS-HAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYS 347
Query: 266 TKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNE-------NY 318
T +D+WS GC+ ELL +P+FPG+S+IDQ+ ++ K LGTP+ + +E +
Sbjct: 348 TAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKMTF 407
Query: 319 SEHKFPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSA 360
SEH + +R R + + DL+ + Y P R SA
Sbjct: 408 SEHPYNNLR----KRFGALLSDQGFDLMNKFLTYFPGRRISA 445
>Hs16332358 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 782
Score = 137 bits (345), Expect = 3e-32
Identities = 84/282 (29%), Positives = 152/282 (53%), Gaps = 25/282 (8%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN------RELEIMKLISHPNLIDLKYY 146
+ G++GVV+R K K+T E V +K++ ++ + RE+ + HPN++ ++
Sbjct: 431 IEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREI 490
Query: 147 FLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVVN 206
+ + ++Y+ +++Y+ L ++ ++ QP E+K M QL + + +LH
Sbjct: 491 VVGSNMDKIYI--VMNYVEHDLKSLME---TMKQPFLPGEVKTLMIQLLRGVKHLHDNW- 544
Query: 207 VCHRDIKPQNILVDPDTLLLKICDLGSAKQL-KPNEPNVSYICSRYYRAPELIFGATNYT 265
+ HRD+K N+L+ +LK+ D G A++ P + + + +YRAPEL+ GA Y+
Sbjct: 545 ILHRDLKTSNLLLS-HAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYS 603
Query: 266 TKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNE-------NY 318
T +D+WS GC+ ELL +P+FPG+S+IDQ+ ++ K LGTP+ + +E +
Sbjct: 604 TAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKMTF 663
Query: 319 SEHKFPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSA 360
SEH + +R R + + DL+ + Y P R SA
Sbjct: 664 SEHPYNNLR----KRFGALLSDQGFDLMNKFLTYFPGRRISA 701
>Hs10835055 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 795
Score = 137 bits (345), Expect = 3e-32
Identities = 84/282 (29%), Positives = 152/282 (53%), Gaps = 25/282 (8%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN------RELEIMKLISHPNLIDLKYY 146
+ G++GVV+R K K+T E V +K++ ++ + RE+ + HPN++ ++
Sbjct: 444 IEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREI 503
Query: 147 FLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVVN 206
+ + ++Y+ +++Y+ L ++ ++ QP E+K M QL + + +LH
Sbjct: 504 VVGSNMDKIYI--VMNYVEHDLKSLME---TMKQPFLPGEVKTLMIQLLRGVKHLHDNW- 557
Query: 207 VCHRDIKPQNILVDPDTLLLKICDLGSAKQL-KPNEPNVSYICSRYYRAPELIFGATNYT 265
+ HRD+K N+L+ +LK+ D G A++ P + + + +YRAPEL+ GA Y+
Sbjct: 558 ILHRDLKTSNLLLS-HAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYS 616
Query: 266 TKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNE-------NY 318
T +D+WS GC+ ELL +P+FPG+S+IDQ+ ++ K LGTP+ + +E +
Sbjct: 617 TAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKMTF 676
Query: 319 SEHKFPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSA 360
SEH + +R R + + DL+ + Y P R SA
Sbjct: 677 SEHPYNNLR----KRFGALLSDQGFDLMNKFLTYFPGRRISA 714
>At4g22940 [D] KOG0600 Cdc2-related protein kinase
Length = 458
Score = 137 bits (345), Expect = 3e-32
Identities = 94/293 (32%), Positives = 152/293 (51%), Gaps = 24/293 (8%)
Query: 91 EIVGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN------RELEIMKLISHPNLIDLK 144
E +G G+F VF+ + + V +K++ D RE+ I++ + HPN+I L+
Sbjct: 107 EQIGGGTFSKVFKARDLLRNKTVALKRIRFDINNSESIKCIAREIIILRKLDHPNVIKLE 166
Query: 145 YYFLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQV 204
L D L LI +YM L L + +H ++K YM QL + L++ H
Sbjct: 167 GLMLVDHDSST-LYLIFEYMEHDLLG-LSSLLGVH--FSEPQVKCYMRQLLRGLDHCH-T 221
Query: 205 VNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNE--PNVSYICSRYYRAPELIFGAT 262
+V HRD+K N+L++ D +L KI D G A P+ P +++ + +YR PEL+ GA+
Sbjct: 222 NHVLHRDMKSSNLLINGDGVL-KIADFGLATFFDPHNSVPLTTHVATLWYRPPELLLGAS 280
Query: 263 NYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENYSEHK 322
+Y +D+WS GCV+ EL G+PI PG+++ DQL +I K+ G+P+ + + S
Sbjct: 281 HYGIGVDLWSTGCVIGELYAGKPILPGKNETDQLHKIFKLCGSPSDDYWTKLKLQLS--- 337
Query: 323 FPQIRPI-----PLNRIFKKETQETIDLLYHIMKYDPNIRYSALQCMFNSTYF 370
+RPI + FK+ I LL ++ DP+ R +A + S YF
Sbjct: 338 -TPLRPIYPYGSHIAETFKQFPASVISLLETLLSIDPDFRGTAASAL-KSKYF 388
>Hs4506785 [T] KOG0660 Mitogen-activated protein kinase
Length = 367
Score = 137 bits (344), Expect = 4e-32
Identities = 90/279 (32%), Positives = 142/279 (50%), Gaps = 20/279 (7%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKV---LQDRRFKNR---ELEIMKLISHPNLIDLKYY 146
VG+G++G V TG V IKK+ Q F R EL ++K + H N+I L
Sbjct: 33 VGSGAYGAVCSAVDGRTGAKVAIKKLYRPFQSELFAKRAYRELRLLKHMRHENVIGLLDV 92
Query: 147 FL--EQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQV 204
F E D L++ +M L + +K H+ + I+ ++Q+ K L Y+H
Sbjct: 93 FTPDETLDDFTDFYLVMPFMGTDLGKLMK-----HEKLGEDRIQFLVYQMLKGLRYIH-A 146
Query: 205 VNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGATNY 264
+ HRD+KP N+ V+ D L KI D G A+Q + Y+ +R+YRAPE+I Y
Sbjct: 147 AGIIHRDLKPGNLAVNEDCEL-KILDFGLARQA--DSEMTGYVVTRWYRAPEVILNWMRY 203
Query: 265 TTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENYSEHK-- 322
T +DIWS GC+MAE++ G+ +F G +DQL EI+KV GTP E + + + +++
Sbjct: 204 TQTVDIWSVGCIMAEMITGKTLFKGSDHLDQLKEIMKVTGTPPAEFVQRLQSDEAKNNMK 263
Query: 323 -FPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSA 360
P++ I + ++LL ++ D R +A
Sbjct: 264 GLPELEKKDFASILTNASPLAVNLLEKMLVLDAEQRVTA 302
>YBR160w [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 298
Score = 136 bits (343), Expect = 5e-32
Identities = 94/283 (33%), Positives = 151/283 (53%), Gaps = 21/283 (7%)
Query: 91 EIVGNGSFGVVFRTKVKETGED---VVIKKVLQDRRFKN------RELEIMKLISHPNLI 141
E VG G++GVV++ G+ V +KK+ + + RE+ ++K + N++
Sbjct: 12 EKVGEGTYGVVYKALDLRPGQGQRVVALKKIRLESEDEGVPSTAIREISLLKELKDDNIV 71
Query: 142 DLKYYFLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYL 201
L Y + +LYL + +++ + L +R E I QP+ +K +M QL K + Y
Sbjct: 72 RL-YDIVHSDAHKLYL--VFEFLDLDL-KRYMEGIPKDQPLGADIVKKFMMQLCKGIAYC 127
Query: 202 HQVVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLK-PNEPNVSYICSRYYRAPELIFG 260
H + HRD+KPQN+L++ D L K+ D G A+ P I + +YRAPE++ G
Sbjct: 128 HSH-RILHRDLKPQNLLINKDGNL-KLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLG 185
Query: 261 ATNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTR---EEICSMNEN 317
Y+T +D WS GC+ AE+ +PIF G+S+IDQ+ +I +VLGTP +I + +
Sbjct: 186 GKQYSTGVDTWSIGCIFAEMCNRKPIFSGDSEIDQIFKIFRVLGTPNEAIWPDIVYLPD- 244
Query: 318 YSEHKFPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSA 360
+ FPQ R L+++ IDLL ++ YDP R SA
Sbjct: 245 -FKPSFPQWRRKDLSQVVPSLDPRGIDLLDKLLAYDPINRISA 286
>Hs7706445 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 515
Score = 136 bits (343), Expect = 5e-32
Identities = 96/306 (31%), Positives = 163/306 (52%), Gaps = 41/306 (13%)
Query: 78 NPEESVVISCGTPEIVGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN--------REL 129
+P++ + I P +G G+FGVV+ G+ V +KK+ F+N REL
Sbjct: 119 HPQQQLDIEPDRP--IGYGAFGVVWSVTDPRDGKRVALKKM--PNVFQNLVSCKRVFREL 174
Query: 130 EIMKLISHPNLID---------LKYYFLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQ 180
+++ H N++ + Y+ +E+Y+ + + M L++ I Q
Sbjct: 175 KMLCFFKHDNVLSALDILQPPHIDYF------EEIYV--VTELMQSDLHK----IIVSPQ 222
Query: 181 PMDRYEIKIYMFQLFKSLNYLHQVVNVCHRDIKPQNILVDPDTLLLKICDLGSAK--QLK 238
P+ +K++++Q+ + L YLH + HRDIKP N+LV+ + +L KICD G A+ +L
Sbjct: 223 PLSSDHVKVFLYQILRGLKYLHSA-GILHRDIKPGNLLVNSNCVL-KICDFGLARVEELD 280
Query: 239 PNEPNVSYICSRYYRAPELIFGATNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVE 298
+ + ++YYRAPE++ G+ +Y+ IDIWS GC+ AELL + +F +S I QL
Sbjct: 281 ESRHMTQEVVTQYYRAPEILMGSRHYSNAIDIWSVGCIFAELLGRRILFQAQSPIQQLDL 340
Query: 299 IIKVLGTPTREEICSMNENYSEH--KFPQIRP-IP-LNRIFKKETQETIDLLYHIMKYDP 354
I +LGTP+ E + + E H + P +P +P L + + T E + LL ++ +DP
Sbjct: 341 ITDLLGTPSLEAMRTACEGAKAHILRGPHKQPSLPVLYTLSSQATHEAVHLLCRMLVFDP 400
Query: 355 NIRYSA 360
+ R SA
Sbjct: 401 SKRISA 406
>Hs5453860 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 496
Score = 136 bits (343), Expect = 5e-32
Identities = 82/280 (29%), Positives = 153/280 (54%), Gaps = 17/280 (6%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQDRR-----FKNRELEIMKLISHPNLIDLKYYF 147
+G G++ V++ K K T V +K++ + RE+ ++K + H N++ L
Sbjct: 171 LGEGTYATVYKGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLH--- 227
Query: 148 LEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVVNV 207
+ E L L+ +Y+ L Q L + ++ ++ + +K+++FQL + L Y H+ V
Sbjct: 228 -DIIHTEKSLTLVFEYLDKDLKQYLDDCGNI---INMHNVKLFLFQLLRGLAYCHRQ-KV 282
Query: 208 CHRDIKPQNILVDPDTLLLKICDLGSAKQLK-PNEPNVSYICSRYYRAPELIFGATNYTT 266
HRD+KPQN+L++ + LK+ D G A+ P + + + + +YR P+++ G+T+Y+T
Sbjct: 283 LHRDLKPQNLLIN-ERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYST 341
Query: 267 KIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSM--NENYSEHKFP 324
+ID+W GC+ E+ G+P+FPG + +QL I ++LGTPT E + NE + + +P
Sbjct: 342 QIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKTYNYP 401
Query: 325 QIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSALQCM 364
+ R L + + DLL +++++ R SA M
Sbjct: 402 KYRAEALLSHAPRLDSDGADLLTKLLQFEGRNRISAEDAM 441
>Hs15011928 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 448
Score = 136 bits (343), Expect = 5e-32
Identities = 82/280 (29%), Positives = 153/280 (54%), Gaps = 17/280 (6%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQDRR-----FKNRELEIMKLISHPNLIDLKYYF 147
+G G++ V++ K K T V +K++ + RE+ ++K + H N++ L
Sbjct: 123 LGEGTYATVYKGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLH--- 179
Query: 148 LEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVVNV 207
+ E L L+ +Y+ L Q L + ++ ++ + +K+++FQL + L Y H+ V
Sbjct: 180 -DIIHTEKSLTLVFEYLDKDLKQYLDDCGNI---INMHNVKLFLFQLLRGLAYCHRQ-KV 234
Query: 208 CHRDIKPQNILVDPDTLLLKICDLGSAKQLK-PNEPNVSYICSRYYRAPELIFGATNYTT 266
HRD+KPQN+L++ + LK+ D G A+ P + + + + +YR P+++ G+T+Y+T
Sbjct: 235 LHRDLKPQNLLIN-ERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYST 293
Query: 267 KIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSM--NENYSEHKFP 324
+ID+W GC+ E+ G+P+FPG + +QL I ++LGTPT E + NE + + +P
Sbjct: 294 QIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKTYNYP 353
Query: 325 QIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSALQCM 364
+ R L + + DLL +++++ R SA M
Sbjct: 354 KYRAEALLSHAPRLDSDGADLLTKLLQFEGRNRISAEDAM 393
>At1g74330 [D] KOG0600 Cdc2-related protein kinase
Length = 445
Score = 136 bits (342), Expect = 7e-32
Identities = 101/293 (34%), Positives = 152/293 (51%), Gaps = 21/293 (7%)
Query: 91 EIVGNGSFGVVFRTKVKETGEDVVIKKVLQDR------RFKNRELEIMKLISHPNLIDLK 144
E +G G++ VFR ETG V +KKV D +F RE+ I++ ++HPN+I L+
Sbjct: 125 EKIGQGTYSNVFRAVETETGRIVALKKVRFDNFEPESVKFMAREILILRRLNHPNIIKLE 184
Query: 145 YYFLEQSDQELYLNLIVDYMPMSLYQRLKE-FISLHQPMDRYEIKIYMFQLFKSLNYLHQ 203
L S + L+ +YM L L I P +IK YM QL L++ H
Sbjct: 185 G--LITSKLSCNIQLVFEYMEHDLTGLLSSPDIKFTTP----QIKCYMKQLLSGLDHCHS 238
Query: 204 VVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPN----EPNVSYICSRYYRAPELIF 259
V HRDIK N+L+ + +L K+ D G A + +P S + + +YR PEL+
Sbjct: 239 R-GVMHRDIKGSNLLLSNEGIL-KVADFGLANFSNSSGHKKKPLTSRVVTLWYRPPELLL 296
Query: 260 GATNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENYS 319
GAT+Y +D+WS GCV AELLLG+PI G ++++QL +I K+ G+P + ++
Sbjct: 297 GATDYGASVDLWSVGCVFAELLLGKPILRGRTEVEQLHKIFKLCGSPPEDYWKKSKLPHA 356
Query: 320 EHKFPQIRPIPLNRIFKKETQET-IDLLYHIMKYDPNIRYSALQCMFNSTYFT 371
PQ R K+ ET I+L+ ++ DP+ R +A + S YFT
Sbjct: 357 MLFKPQQTYDSCLRETLKDLSETEINLIETLLSIDPHKRGTASSALV-SQYFT 408
>SPBC119.08 [T] KOG0660 Mitogen-activated protein kinase
Length = 422
Score = 135 bits (341), Expect = 9e-32
Identities = 94/289 (32%), Positives = 145/289 (49%), Gaps = 33/289 (11%)
Query: 93 VGNGSFGVVF--RTKVKETGEDVVIKK---VLQDRRFKNRELEIMKLISHPNLIDLKYYF 147
+G G++G+V R + E V IKK V R L +KL+ H F
Sbjct: 27 LGQGAYGIVCAARNVASKDQEAVAIKKITNVFSKSILTKRALREIKLLIH---------F 77
Query: 148 LEQSDQELYLNLIV----DYMPMSLYQRLKE-----FISLHQPMDRYEIKIYMFQLFKSL 198
+ +L + ++ + +Y+ L E I QP+ + +++Q+ L
Sbjct: 78 RNHRNITCIYDLDIINPYNFNEVYIYEELMEADLNAIIKSGQPLTDAHFQSFIYQILCGL 137
Query: 199 NYLHQVVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPN-EPN----VSYICSRYYR 253
Y+H NV HRD+KP N+LV+ D L KICD G A+ N E N Y+ +R+YR
Sbjct: 138 KYIHSA-NVIHRDLKPGNLLVNADCEL-KICDFGLARGCSENPEENPGFMTEYVATRWYR 195
Query: 254 APELIFGATNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICS 313
APE++ ++Y ID+WS GC++AELL G P+F G+ + QL I+ LGTP E +
Sbjct: 196 APEIMLSFSSYHKGIDVWSVGCILAELLGGTPLFKGKDFVHQLNLILHQLGTPDEETLSH 255
Query: 314 MNENYSE---HKFPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYS 359
++ + ++ P+ RPIP F K +DLL ++ +DPN R S
Sbjct: 256 ISSSRAQEYVRSLPKQRPIPFETNFPKANPLALDLLAKLLAFDPNRRIS 304
>CE20258 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 353
Score = 135 bits (341), Expect = 9e-32
Identities = 95/322 (29%), Positives = 163/322 (50%), Gaps = 24/322 (7%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQD------RRFKNRELEIMKLISHPNLIDLKYY 146
+G GS+GVV++ K ++TG+ V IKK ++ ++ RE+ ++K + H NL+ L
Sbjct: 10 LGEGSYGVVYKCKNRDTGQIVAIKKFVETEDDPHIKKIALREIRMLKQLKHQNLVGL--- 66
Query: 147 FLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVVN 206
+E + L+L+ + ++ L++ + H D IK ++QL ++L + H
Sbjct: 67 -IEVFKRNRKLHLVFELCDRTVLHELEK--NPHGVNDEL-IKKIIYQLLEALKFCHSHKC 122
Query: 207 VCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGATNYTT 266
+ HRD+KP+NI + + + K+ D G A+ + E Y+ +R+YR+PEL+ G Y
Sbjct: 123 I-HRDVKPENIFLTRNDQV-KLGDFGFARIINTTEMYTDYVATRWYRSPELLVGDVQYGP 180
Query: 267 KIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLG--TPTREEICSMNENYSEHKFP 324
+DIW+ GCV AELL G+ ++PG S IDQL I K LG P I N+ + P
Sbjct: 181 PVDIWAVGCVYAELLTGEALWPGRSDIDQLYHIRKTLGEFLPRHISIFRTNQFFFGLSIP 240
Query: 325 QIRPI-PLNRIFKKETQETIDLLYHIMKYDPNIRYSALQCMFNSTYFTDIVSNTGSDSNL 383
+ + PL + +D L + P+ R+S + M + + I+ +S
Sbjct: 241 EPEHLEPLPSKLPNASSAQLDFLQKCFEMSPDRRFSCSELMLHGIFSNWILRIRQDESTP 300
Query: 384 SLIDS------LPLLHFEESEL 399
+ + S LPLL+ + L
Sbjct: 301 TGLTSKRSPNYLPLLNGNSNNL 322
>At1g18670 [D] KOG0600 Cdc2-related protein kinase
Length = 662
Score = 135 bits (341), Expect = 9e-32
Identities = 84/229 (36%), Positives = 128/229 (55%), Gaps = 18/229 (7%)
Query: 91 EIVGNGSFGVVFRTKVKETGEDVVIKKVLQDR------RFKNRELEIMKLISHPNLIDLK 144
E +G G++ VFR + ETG V +KKV D RF RE+ I++ ++HPN+I L+
Sbjct: 135 EKIGQGTYSSVFRARETETGRIVALKKVRFDNFEPESVRFMAREILILRKLNHPNIIKLE 194
Query: 145 YYFLEQSDQELYLNLIVDYMPMSLYQRLKE-FISLHQPMDRYEIKIYMFQLFKSLNYLHQ 203
+ S ++L+ +YM L L I P +IK YM QL L++ H
Sbjct: 195 G--IVTSKLSCSIHLVFEYMEHDLTGLLSSPDIDFTTP----QIKCYMKQLLSGLDHCH- 247
Query: 204 VVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPN---EPNVSYICSRYYRAPELIFG 260
V HRDIK N+LV+ + +L K+ D G A + +P S + + +YR PEL+ G
Sbjct: 248 ARGVMHRDIKGSNLLVNNEGIL-KVADFGLANFCNASGNKQPLTSRVVTLWYRPPELLLG 306
Query: 261 ATNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTRE 309
AT Y +D+WS GCV AELL+G+P+ G ++++QL +I K+ G+P +
Sbjct: 307 ATEYGASVDLWSVGCVFAELLIGKPVLQGRTEVEQLHKIFKLCGSPPED 355
>Hs16160923 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 472
Score = 135 bits (340), Expect = 1e-31
Identities = 93/317 (29%), Positives = 166/317 (52%), Gaps = 25/317 (7%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQDRR-----FKNRELEIMKLISHPNLIDLKYYF 147
+G G++ VF+ + K T V +K++ + RE+ ++K + H N++ L +
Sbjct: 148 LGEGTYATVFKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKNLKHANIVTL--HD 205
Query: 148 LEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVVNV 207
L +D+ L L+ +Y+ L Q L +L M + +KI+MFQL + L Y H +
Sbjct: 206 LIHTDRSL--TLVFEYLDSDLKQYLDHCGNL---MSMHNVKIFMFQLLRGLAYCHHR-KI 259
Query: 208 CHRDIKPQNILVDPDTLLLKICDLGSAKQLK-PNEPNVSYICSRYYRAPELIFGATNYTT 266
HRD+KPQN+L++ + LK+ D G A+ P + + + + +YR P+++ G+T Y+T
Sbjct: 260 LHRDLKPQNLLIN-ERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYST 318
Query: 267 KIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREE---ICSMNENYSEHKF 323
ID+W GC+ E+ G+P+FPG + ++L I ++LGTPT E + + +E + + F
Sbjct: 319 PIDMWGVGCIHYEMATGRPLFPGSTVKEELHLIFRLLGTPTEETWPGVTAFSE-FRTYSF 377
Query: 324 PQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSALQCMFNSTYFTDIVSNTGSDSNL 383
P P PL + + I LL ++ Y+ R SA + + +YF + +
Sbjct: 378 PCYLPQPLINHAPRLDTDGIHLLSSLLLYESKSRMSA-EAALSHSYFRSL-----GERVH 431
Query: 384 SLIDSLPLLHFEESELQ 400
L D+ + +E +LQ
Sbjct: 432 QLEDTASIFSLKEIQLQ 448
>At4g10010 [D] KOG0600 Cdc2-related protein kinase
Length = 649
Score = 135 bits (340), Expect = 1e-31
Identities = 96/296 (32%), Positives = 156/296 (52%), Gaps = 33/296 (11%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVL------QDRRFKNRELEIMKLISHPNLIDLKYY 146
+G G++ V+R + ETG+ V +KKV + RF RE+ I++ + HPN++ L+
Sbjct: 162 IGQGTYSSVYRARDLETGKMVAMKKVRFVNMDPESVRFMAREINILRKLDHPNVMKLECL 221
Query: 147 FLEQSDQELYLNLIVDYMPMSLYQ-RLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVV 205
+ LYL + +YM L L+ + + +IK YM QL L + H
Sbjct: 222 VTSKLSGSLYL--VFEYMEHDLSGLALRPGVKFTES----QIKCYMKQLLSGLEHCHSR- 274
Query: 206 NVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKP--NEPNVSYICSRYYRAPELIFGATN 263
+ HRDIK N+LV+ D +L KI D G A P ++P S + + +YRAPEL+ GAT
Sbjct: 275 GILHRDIKGPNLLVNNDGVL-KIGDFGLANIYHPEQDQPLTSRVVTLWYRAPELLLGATE 333
Query: 264 YTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENYSEHKF 323
Y ID+WS GC++ EL LG+PI PG ++++Q+ +I K G+P+ ++ + + K
Sbjct: 334 YGPGIDLWSVGCILTELFLGKPIMPGRTEVEQMHKIFKFCGSPS-------DDYWQKTKL 386
Query: 324 P---QIRP-IPLNRI----FKKETQETIDLLYHIMKYDPNIRYSALQCMFNSTYFT 371
P +P P R+ FK + L+ ++ +P R +A + +S +FT
Sbjct: 387 PLATSFKPQQPYKRVLLETFKNLPPSALALVDKLLSLEPAKRGTASSTL-SSKFFT 441
>7296346 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 952
Score = 134 bits (338), Expect = 2e-31
Identities = 86/288 (29%), Positives = 153/288 (52%), Gaps = 29/288 (10%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN------RELEIMKLISHPNLIDLKYY 146
+ G++GVV+R K K T E V +K++ ++ + RE+ + HPN++ ++
Sbjct: 564 IEEGTYGVVYRAKDKRTNEIVALKRLKMEKEKEGFPITSLREINTLLKGQHPNIVTVREI 623
Query: 147 FLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVVN 206
+ + ++++ ++DY+ L ++ + Q E+K QL +++ +LH
Sbjct: 624 VVGSNMDKIFI--VMDYVEHDLKSLMETMKNRKQSFFPGEVKCLTQQLLRAVAHLHDNW- 680
Query: 207 VCHRDIKPQNILVDPDTLLLKICDLGSAKQL-KPNEPNVSYICSRYYRAPELIFGATNYT 265
+ HRD+K N+L+ +L K+ D G A++ P + S + + +YRAPEL+ + Y+
Sbjct: 681 ILHRDLKTSNLLLSHKGIL-KVGDFGLAREYGSPIKKYTSLVVTLWYRAPELLLCSPVYS 739
Query: 266 TKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTR------------EEICS 313
T ID+WS GC+ AE L P+FPG+S+ID+L I K LGTP + + S
Sbjct: 740 TPIDVWSVGCIFAEFLQMLPLFPGKSEIDELNRIFKELGTPNEKIWPGYTELPAVKNMLS 799
Query: 314 MNENYSEHKFPQIRPIPLNRIFKKETQET-IDLLYHIMKYDPNIRYSA 360
N ++E+ Q+R + F+++T E + LL ++ YDP R SA
Sbjct: 800 QNSQFTEYPVSQLR-----KHFQEKTSEMGLSLLQGLLTYDPKQRLSA 842
>CE19302_1 [G] KOG0658 Glycogen synthase kinase-3
Length = 396
Score = 134 bits (337), Expect = 2e-31
Identities = 86/275 (31%), Positives = 138/275 (49%), Gaps = 19/275 (6%)
Query: 96 GSFGVVFRTKVKETG--EDVVIKKVLQDRRFKNRELEIMKLIS---HPNLIDLKYYFLEQ 150
G F V+R + G +++ IKK ++N EL + + H N++ + + F
Sbjct: 36 GVFSNVYRGTILSPGTEQEIAIKKTWPKTPYRNFELLFLSGLRRKPHKNIVQMLFAFSRN 95
Query: 151 SDQELYLNL--------IVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLH 202
+ L + + +MP +L LK+ + ++K+Y +QLF+ + YL
Sbjct: 96 TTSGEGLEMKHSFCESYVFGFMPYTLQNILKK-----TRLAEVDMKLYTWQLFEGIRYL- 149
Query: 203 QVVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGAT 262
Q + HRDIKP NILVD D LKI D GSAK + + SY +R+YR PEL+ A
Sbjct: 150 QAHMIVHRDIKPVNILVDVDKGTLKIADFGSAKVVLRGSSSTSYQVTRFYRPPELLLDAK 209
Query: 263 NYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENYSEHK 322
Y +D+WSAGC + E++ G+ +FPG S L I++ +G P+ ++ M + +
Sbjct: 210 EYYWMVDVWSAGCCVGEMMKGKVLFPGASIKIMLKLIVQAIGLPSARDLDYMKVSSMIDQ 269
Query: 323 FPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIR 357
++ I L + E QE D L I++Y P R
Sbjct: 270 QSAVKVIGLKEVLGTENQEWADFLGAILRYRPRER 304
>YBL016w [T] KOG0660 Mitogen-activated protein kinase
Length = 353
Score = 134 bits (336), Expect = 3e-31
Identities = 89/293 (30%), Positives = 153/293 (51%), Gaps = 26/293 (8%)
Query: 92 IVGNGSFGVVFRTKVKETGEDVVIKKVLQ-DRRF----KNRELEIMKLISHPNLIDLKYY 146
++G G++GVV K TGE V IKK+ D+ RE++I+K H N+I + +
Sbjct: 18 LLGEGAYGVVCSATHKPTGEIVAIKKIEPFDKPLFALRTLREIKILKHFKHENIITI--F 75
Query: 147 FLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVVN 206
+++ D N + Y+ L Q + Q + I+ +++Q +++ LH N
Sbjct: 76 NIQRPDSFENFNEV--YIIQELMQTDLHRVISTQMLSDDHIQYFIYQTLRAVKVLHGS-N 132
Query: 207 VCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPN-----EPN------VSYICSRYYRAP 255
V HRD+KP N+L++ + L K+CD G A+ + + EP Y+ +R+YRAP
Sbjct: 133 VIHRDLKPSNLLINSNCDL-KVCDFGLARIIDESAADNSEPTGQQSGMTEYVATRWYRAP 191
Query: 256 ELIFGATNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMN 315
E++ + Y+ +D+WS GC++AEL L +PIFPG QL+ I ++GTP +
Sbjct: 192 EVMLTSAKYSRAMDVWSCGCILAELFLRRPIFPGRDYRHQLLLIFGIIGTPHSDNDLRCI 251
Query: 316 ENYSEHKF----PQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSALQCM 364
E+ ++ P PL ++F + + IDLL ++ +DP R +A + +
Sbjct: 252 ESPRAREYIKSLPMYPAAPLEKMFPRVNPKGIDLLQRMLVFDPAKRITAKEAL 304
>At5g63610 [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 470
Score = 134 bits (336), Expect = 3e-31
Identities = 95/312 (30%), Positives = 159/312 (50%), Gaps = 38/312 (12%)
Query: 93 VGNGSFGVVFRTKVKETGE-DVVIKKVLQDRRFKN------RELEIMKLISHPNLIDLKY 145
+G G++G+VF + K + + IKK Q + RE+ +++ ISH N++ L
Sbjct: 31 IGEGTYGLVFLARTKTPPKRPIAIKKFKQSKDGDGVSPTAIREIMLLREISHENVVKLVN 90
Query: 146 YFLEQSDQELYLNLIVDYMPMSLYQRLKEFIS-LHQPMDRYEIKIYMFQLFKSLNYLHQV 204
+ +D LYL DY LY+ ++ + ++ Y +K ++QL LNYLH
Sbjct: 91 VHINFADMSLYLAF--DYAEYDLYEIIRHHRDKVGHSLNTYTVKSLLWQLLNGLNYLHSN 148
Query: 205 VNVCHRDIKPQNILVDPDTL---LLKICDLGSAK----QLKPNEPNVSYICSRYYRAPEL 257
+ HRD+KP NILV D ++KI D G A+ LKP N + + +YRAPEL
Sbjct: 149 W-IIHRDLKPSNILVMGDAEEHGIVKIADFGLARIYQAPLKPLSDN-GVVVTIWYRAPEL 206
Query: 258 IFGATNYTTKIDIWSAGCVMAELLLGQPIFPGES--------KIDQLVEIIKVLGTPTRE 309
+ G+ +YT+ +D+W+ GC+ AELL +P+F G ++DQL +I K+LG PT +
Sbjct: 207 LLGSKHYTSAVDMWAVGCIFAELLTLKPLFQGAEAKSSQNPFQLDQLDKIFKILGHPTMD 266
Query: 310 EICSM---------NENYSEHKFPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSA 360
+ ++ ++ HK+ + N + + DLL +++YDP R +A
Sbjct: 267 KWPTLVNLPHWQNDVQHIQAHKYDSVG--LHNVVHLNQKSPAYDLLSKMLEYDPLKRITA 324
Query: 361 LQCMFNSTYFTD 372
Q + + + D
Sbjct: 325 SQALEHEYFRMD 336
>7295173 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 474
Score = 134 bits (336), Expect = 3e-31
Identities = 85/284 (29%), Positives = 146/284 (50%), Gaps = 17/284 (5%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKV------LQDRRFKNRELEIMKLISHPNLIDLKYY 146
+G G+FGVV+ G V +KK+ L + REL+++ H N++
Sbjct: 46 IGYGAFGVVWAVTDPRDGRRVALKKLPNVFQSLVSSKRVFRELKMLCFFKHENVLSA-LD 104
Query: 147 FLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVVN 206
L+ + + + V + L L + I Q + IK++++Q+ + L YLH
Sbjct: 105 ILQPPHLDFFQEIYV--ITELLQSDLHKIIVSPQHLSADHIKVFLYQILRGLKYLHSA-R 161
Query: 207 VCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPN--VSYICSRYYRAPELIFGATNY 264
+ HRDIKP N+LV+ + +L KICD G A+ +P++ + ++YYRAPE++ GA +Y
Sbjct: 162 ILHRDIKPGNLLVNSNCVL-KICDFGLARVEEPDQAKHMTQEVVTQYYRAPEILMGARHY 220
Query: 265 TTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENYSEHKFP 324
++ +D+WS GC+ ELL + +F ++ + QL I ++LGTPT E++ E H
Sbjct: 221 SSAVDVWSVGCIFGELLGRRILFQAQNPVQQLELITELLGTPTMEDMRHACEGARTHMLR 280
Query: 325 QIRPIP----LNRIFKKETQETIDLLYHIMKYDPNIRYSALQCM 364
+ P L + T E + LL ++ +DP+ R S +
Sbjct: 281 RAPKPPSFSVLYTLSSHATHEAVHLLCQMLVFDPDKRISVTDAL 324
>YGR040w [T] KOG0660 Mitogen-activated protein kinase
Length = 368
Score = 133 bits (335), Expect = 4e-31
Identities = 86/294 (29%), Positives = 153/294 (51%), Gaps = 22/294 (7%)
Query: 91 EIVGNGSFGVVFRTKVKETGEDVVIKKV--LQDRRFKNRELEIMKLI----SHPNLIDLK 144
+++G G++G V K +G V IKK+ + F R + +KL+ H N+I +
Sbjct: 17 DLIGEGAYGTVCSAIHKPSGIKVAIKKIQPFSKKLFVTRTIREIKLLRYFHEHENIISIL 76
Query: 145 YYFLEQSDQELY-LNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQ 203
S +L + L+ + M L + + S + ++ + +Q+ ++L +H
Sbjct: 77 DKVRPVSIDKLNAVYLVEELMETDLQKVINNQNSGFSTLSDDHVQYFTYQILRALKSIHS 136
Query: 204 VVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPN--------VSYICSRYYRAP 255
V HRDIKP N+L++ + L K+CD G A+ L + + Y+ +R+YRAP
Sbjct: 137 A-QVIHRDIKPSNLLLNSNCDL-KVCDFGLARCLASSSDSRETLVGFMTEYVATRWYRAP 194
Query: 256 ELIFGATNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMN 315
E++ YTT +DIWS GC++AE++ G+P+FPG QL I++VLGTP+ E+ +
Sbjct: 195 EIMLTFQEYTTAMDIWSCGCILAEMVSGKPLFPGRDYHHQLWLILEVLGTPSFEDFNQIK 254
Query: 316 ENYSEH---KFPQIRPIPLNRIFKKE--TQETIDLLYHIMKYDPNIRYSALQCM 364
++ P P+P ++ K + IDLL +++++P+ R SA + +
Sbjct: 255 SKRAKEYIANLPMRPPLPWETVWSKTDLNPDMIDLLDKMLQFNPDKRISAAEAL 308
>HsM20070143 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 424
Score = 133 bits (335), Expect = 4e-31
Identities = 95/292 (32%), Positives = 147/292 (49%), Gaps = 37/292 (12%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN--------RELEIMKLISHPNLIDLK 144
+G+G+ G+V G +V +KK+ R F+N REL ++K ++H N+I L
Sbjct: 32 IGSGAQGIVCAAFDTVLGINVAVKKL--SRPFQNQTHAKRAYRELVLLKCVNHKNIISLL 89
Query: 145 YYFLEQSDQELYLN--LIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLH 202
F Q E + + L+++ M +L Q +H +D + ++Q+ + +LH
Sbjct: 90 NVFTPQKTLEEFQDVYLVMELMDANLCQ------VIHMELDHERMSYLLYQMLCGIKHLH 143
Query: 203 QVVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGAT 262
+ HRD+KP NI+V D L KI D G A+ N Y+ +RYYRAPE+I G
Sbjct: 144 SA-GIIHRDLKPSNIVVKSDCTL-KILDFGLARTACTNFMMTPYVVTRYYRAPEVILGM- 200
Query: 263 NYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMN---ENYS 319
Y +DIWS GC+M EL+ G IF G IDQ ++I+ LGTP+ E + + NY
Sbjct: 201 GYKENVDIWSVGCIMGELVKGCVIFQGTDHIDQWNKVIEQLGTPSAEFMKKLQPTVRNYV 260
Query: 320 EHKFPQIRPIPLNRIF------------KKETQETIDLLYHIMKYDPNIRYS 359
E++ P+ I +F K +T + DLL ++ DP+ R S
Sbjct: 261 ENR-PKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSKMLVIDPDKRIS 311
>Hs21237739 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 382
Score = 133 bits (335), Expect = 4e-31
Identities = 95/292 (32%), Positives = 147/292 (49%), Gaps = 37/292 (12%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN--------RELEIMKLISHPNLIDLK 144
+G+G+ G+V G +V +KK+ R F+N REL ++K ++H N+I L
Sbjct: 32 IGSGAQGIVCAAFDTVLGINVAVKKL--SRPFQNQTHAKRAYRELVLLKCVNHKNIISLL 89
Query: 145 YYFLEQSDQELYLN--LIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLH 202
F Q E + + L+++ M +L Q +H +D + ++Q+ + +LH
Sbjct: 90 NVFTPQKTLEEFQDVYLVMELMDANLCQ------VIHMELDHERMSYLLYQMLCGIKHLH 143
Query: 203 QVVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGAT 262
+ HRD+KP NI+V D L KI D G A+ N Y+ +RYYRAPE+I G
Sbjct: 144 SA-GIIHRDLKPSNIVVKSDCTL-KILDFGLARTACTNFMMTPYVVTRYYRAPEVILGM- 200
Query: 263 NYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMN---ENYS 319
Y +DIWS GC+M EL+ G IF G IDQ ++I+ LGTP+ E + + NY
Sbjct: 201 GYKENVDIWSVGCIMGELVKGCVIFQGTDHIDQWNKVIEQLGTPSAEFMKKLQPTVRNYV 260
Query: 320 EHKFPQIRPIPLNRIF------------KKETQETIDLLYHIMKYDPNIRYS 359
E++ P+ I +F K +T + DLL ++ DP+ R S
Sbjct: 261 ENR-PKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSKMLVIDPDKRIS 311
>Hs21237736 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 424
Score = 133 bits (335), Expect = 4e-31
Identities = 95/292 (32%), Positives = 147/292 (49%), Gaps = 37/292 (12%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN--------RELEIMKLISHPNLIDLK 144
+G+G+ G+V G +V +KK+ R F+N REL ++K ++H N+I L
Sbjct: 32 IGSGAQGIVCAAFDTVLGINVAVKKL--SRPFQNQTHAKRAYRELVLLKCVNHKNIISLL 89
Query: 145 YYFLEQSDQELYLN--LIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLH 202
F Q E + + L+++ M +L Q +H +D + ++Q+ + +LH
Sbjct: 90 NVFTPQKTLEEFQDVYLVMELMDANLCQ------VIHMELDHERMSYLLYQMLCGIKHLH 143
Query: 203 QVVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGAT 262
+ HRD+KP NI+V D L KI D G A+ N Y+ +RYYRAPE+I G
Sbjct: 144 SA-GIIHRDLKPSNIVVKSDCTL-KILDFGLARTACTNFMMTPYVVTRYYRAPEVILGM- 200
Query: 263 NYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMN---ENYS 319
Y +DIWS GC+M EL+ G IF G IDQ ++I+ LGTP+ E + + NY
Sbjct: 201 GYKENVDIWSVGCIMGELVKGCVIFQGTDHIDQWNKVIEQLGTPSAEFMKKLQPTVRNYV 260
Query: 320 EHKFPQIRPIPLNRIF------------KKETQETIDLLYHIMKYDPNIRYS 359
E++ P+ I +F K +T + DLL ++ DP+ R S
Sbjct: 261 ENR-PKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSKMLVIDPDKRIS 311
>CE28918 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 406
Score = 133 bits (335), Expect = 4e-31
Identities = 89/338 (26%), Positives = 180/338 (52%), Gaps = 28/338 (8%)
Query: 44 QGSLHSKNSHGNDVKIVPDEDEVITRRTVVKGHSNPEESVVISC----GTPEI------V 93
Q + K S+ + ++ + I + ++K +N +VV S TP + +
Sbjct: 49 QNNQRQKPSNFHFWTVIKKFSKKILKSFIIKFGNNGTIAVVFSIFPTGATPSLTFLFQAL 108
Query: 94 GNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN------RELEIMKLIS---HPNLIDLK 144
G G++G V+R + G+D +K+++ + + RE+ +MK ++ HPN+I LK
Sbjct: 109 GKGAYGNVYRVRSLHDGKDYALKQIMISSKNEGIPQSVLREITVMKHLARKAHPNIISLK 168
Query: 145 YYF--LEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLH 202
F L+ L +N+I++ L+ L+ ++ + + + K Q+ ++L++LH
Sbjct: 169 SVFHQLDPVRAILKINMIMERCDWDLHTFLR---NIPRGVPEQQAKHVTAQIVRALDFLH 225
Query: 203 QVVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGAT 262
++ HRD+KPQNIL++ D + K+ D G +K+ + + + +YR+PE++ +
Sbjct: 226 -THSIIHRDLKPQNILLNRDQTV-KLADFGLSKEYSNTTAFTTLVVTLWYRSPEVLL-QS 282
Query: 263 NYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENYSEHK 322
Y + +D+W+ GC+++E+ QP+F G+++ +QL +I K +GTP ++ S +
Sbjct: 283 YYNSTVDMWALGCIVSEIYCRQPLFVGQNEAEQLTDIFKKMGTPVGKDWPS-ESVIARDS 341
Query: 323 FPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSA 360
FPQ RP L + + +++ I+ + ++YD + R SA
Sbjct: 342 FPQYRPTNLKDLSPQMSKQAIEFVQQCLRYDHSKRLSA 379
>SPAC31G5.09c [T] KOG0660 Mitogen-activated protein kinase
Length = 372
Score = 133 bits (334), Expect = 6e-31
Identities = 85/302 (28%), Positives = 155/302 (51%), Gaps = 31/302 (10%)
Query: 79 PEESVVISCGTPEIVGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN--------RELE 130
PEE +I+ ++G G++GVV K +G V +KK+ F + RE++
Sbjct: 36 PEEYEMIN-----LIGQGAYGVVCAALHKPSGLKVAVKKI---HPFNHPVFCLRTLREIK 87
Query: 131 IMKLISHPNLIDLKYYFLEQSDQELY-LNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKI 189
+++ H N+I + S QEL + ++ + M LY+ ++ QP+ +
Sbjct: 88 LLRHFRHENIISILDILPPPSYQELEDVYIVQELMETDLYRVIRS-----QPLSDDHCQY 142
Query: 190 YMFQLFKSLNYLHQVVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPN----VS 245
+ +Q+ ++L +H V HRD+KP N+L++ + L K+ D G A+ N
Sbjct: 143 FTYQILRALKAMHSA-GVVHRDLKPSNLLLNANCDL-KVADFGLARSTTAQGGNPGFMTE 200
Query: 246 YICSRYYRAPELIFGATNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGT 305
Y+ +R+YRAPE++ Y+ ID+WS GC++AE+L +P+FPG+ Q+ I+ +LGT
Sbjct: 201 YVATRWYRAPEIMLSFREYSKAIDLWSTGCILAEMLSARPLFPGKDYHSQITLILNILGT 260
Query: 306 PTREE---ICSMNENYSEHKFPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSALQ 362
PT ++ I S P + +F + + + IDLL ++ ++P+ R +A +
Sbjct: 261 PTMDDFSRIKSARARKYIKSLPFTPKVSFKALFPQASPDAIDLLEKLLTFNPDKRITAEE 320
Query: 363 CM 364
+
Sbjct: 321 AL 322
>CE01612 [G] KOG0658 Glycogen synthase kinase-3
Length = 410
Score = 133 bits (334), Expect = 6e-31
Identities = 77/232 (33%), Positives = 132/232 (56%), Gaps = 13/232 (5%)
Query: 91 EIVGNGSFGVVFRTK-VKETGEDVVIKKVLQDRRFKNR------ELEIMKLISHPNLIDL 143
++ G+G F V+ + + ++V +K V D ++ E++I+ + HP + +L
Sbjct: 31 KLCGSGRFSNVYCGQMISPIEKEVAVKNVWSDTETRHLATSEYPEIQILSKLFHPAISNL 90
Query: 144 KYYFLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQ 203
Y++ ++ ++ L++DY+P L + + + D + K+Y FQLF ++++L
Sbjct: 91 LYFYSRNANDKVINCLVLDYLPQDLARLRDQGVKF----DVLDAKLYTFQLFCAISHLTS 146
Query: 204 VVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVS-YICSRYYRAPELIFGAT 262
N+ H DIKPQN+++D LK+ D G+A++L+ NE S Y +R+YR PEL+FG
Sbjct: 147 K-NIVHMDIKPQNVVMDRMAGRLKLADFGNARRLETNEKTGSAYQVTRFYRPPELLFGCE 205
Query: 263 NYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSM 314
+T IDIWSA CV EL + +F G+ DQ+V I V G PT ++I S+
Sbjct: 206 KFTASIDIWSATCVAFELFANRVLFKGKDTKDQIVLITGVFGYPTDDDIKSI 257
>7298087 [T] KOG0660 Mitogen-activated protein kinase
Length = 365
Score = 132 bits (333), Expect = 7e-31
Identities = 104/327 (31%), Positives = 163/327 (49%), Gaps = 41/327 (12%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN--------RELEIMKLISHPNLIDLK 144
VG G++G V + V+ T V IKK+ R F++ REL ++K + H N+I L
Sbjct: 30 VGQGAYGQVCKAVVRGTSTKVAIKKLA--RPFQSAVHAKRTYRELRLLKHMDHENVIGLL 87
Query: 145 YYF-----LEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLN 199
F + DQ + ++ M L ++ Q + ++ ++Q+ + L
Sbjct: 88 DVFHPGQPADSLDQFQQVYMVTHLMDADLNNIIRT-----QKLSDDHVQFLVYQILRGLK 142
Query: 200 YLHQVVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVS-YICSRYYRAPELI 258
Y+H V HRD+KP NI V+ D L +I D G A+ P E ++ Y+ +R+YRAPE++
Sbjct: 143 YIHSA-GVIHRDLKPSNIAVNEDCEL-RILDFGLAR---PAESEMTGYVATRWYRAPEIM 197
Query: 259 FGATNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENY 318
+Y DIWS GC+MAELL G+ +FPG I QL I++VLGTP E M+
Sbjct: 198 LNWMHYNQTADIWSVGCIMAELLTGRTLFPGTDHIHQLNLIMEVLGTPADE---FMSRIS 254
Query: 319 SEHKFPQIRPIPL------NRIFKKETQETIDLLYHIMKYDPNIRYSALQCMFNSTYFTD 372
SE IR +P+ IF+ IDLL +++ D + R +A Q + + + +
Sbjct: 255 SESARNYIRSLPVMPRRNFRDIFRGANPLAIDLLEKMLELDADKRITAEQALAHP--YME 312
Query: 373 IVSNTGSDSNLSLIDSLPLLHFEESEL 399
+ + +L D FEE+EL
Sbjct: 313 KYHDPTDEQTAALYDQ----SFEENEL 335
>CE18608 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 342
Score = 131 bits (330), Expect = 2e-30
Identities = 78/281 (27%), Positives = 158/281 (55%), Gaps = 18/281 (6%)
Query: 91 EIVGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN------RELEIMKLIS---HPNLI 141
+ +G G++G V+R + G+D +K+++ + + RE+ +MK ++ HPN+I
Sbjct: 42 QALGKGAYGNVYRVRSLHDGKDYALKQIMISSKNEGIPQSVLREITVMKHLARKAHPNII 101
Query: 142 DLKYYF--LEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLN 199
LK F L+ L +N+I++ L+ L+ ++ + + + K Q+ ++L+
Sbjct: 102 SLKSVFHQLDPVRAILKINMIMERCDWDLHTFLR---NIPRGVPEQQAKHVTAQIVRALD 158
Query: 200 YLHQVVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIF 259
+LH ++ HRD+KPQNIL++ D + K+ D G +K+ + + + +YR+PE++
Sbjct: 159 FLH-THSIIHRDLKPQNILLNRDQTV-KLADFGLSKEYSNTTAFTTLVVTLWYRSPEVLL 216
Query: 260 GATNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENYS 319
+ Y + +D+W+ GC+++E+ QP+F G+++ +QL +I K +GTP ++ S +
Sbjct: 217 -QSYYNSTVDMWALGCIVSEIYCRQPLFVGQNEAEQLTDIFKKMGTPVGKDWPS-ESVIA 274
Query: 320 EHKFPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSA 360
FPQ RP L + + +++ I+ + ++YD + R SA
Sbjct: 275 RDSFPQYRPTNLKDLSPQMSKQAIEFVQQCLRYDHSKRLSA 315
>At5g64960 [D] KOG0600 Cdc2-related protein kinase
Length = 513
Score = 131 bits (330), Expect = 2e-30
Identities = 93/304 (30%), Positives = 155/304 (50%), Gaps = 27/304 (8%)
Query: 91 EIVGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN------RELEIMKLISHPNLIDLK 144
E +G G++G V+ K +TGE V +KK+ D + RE++I+K + H N+I LK
Sbjct: 30 EQIGEGTYGQVYMAKEIKTGEIVALKKIRMDNEREGFPITAIREIKILKKLHHENVIHLK 89
Query: 145 YYFLE---------QSDQELY---LNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMF 192
+ D Y + ++ +YM L L + L + +IK YM
Sbjct: 90 EIVTSPGRDRDDQGKPDNNKYKGGIYMVFEYMDHDL-TGLADRPGLRFTVP--QIKCYMK 146
Query: 193 QLFKSLNYLHQVVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPN--VSYICSR 250
QL L+Y H V V HRDIK N+L+D + L K+ D G A+ + + + +
Sbjct: 147 QLLTGLHYCH-VNQVLHRDIKGSNLLIDNEGNL-KLADFGLARSYSHDHTGNLTNRVITL 204
Query: 251 YYRAPELIFGATNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREE 310
+YR PEL+ GAT Y ID+WS GC+ AELL G+PI PG+++ +QL +I ++ G+P
Sbjct: 205 WYRPPELLLGATKYGPAIDMWSVGCIFAELLNGKPILPGKTENEQLNKIYELCGSPDESN 264
Query: 311 ICSMNENYSEHKFPQIRPIP--LNRIFKKETQETIDLLYHIMKYDPNIRYSALQCMFNST 368
+++ ++ RP+ + I++ + ++LL ++ DP+ R A +
Sbjct: 265 WPGVSKMPWYNQMKSSRPLKRRVREIYRHFDRHALELLEKMLVLDPSQRICAKDALDAEY 324
Query: 369 YFTD 372
++TD
Sbjct: 325 FWTD 328
>At4g11330 [T] KOG0660 Mitogen-activated protein kinase
Length = 373
Score = 131 bits (330), Expect = 2e-30
Identities = 76/257 (29%), Positives = 140/257 (53%), Gaps = 16/257 (6%)
Query: 108 ETGEDVVIKKVLQ------DRRFKNRELEIMKLISHPNLIDLKYYFLEQSDQELY-LNLI 160
ET E++ IKK+ + D + RE+++++ + H N++ +K ++ + ++
Sbjct: 61 ETHEEIAIKKIGKAFDNKVDAKRTLREIKLLRHLEHENVVVIKDIIRPPKKEDFVDVYIV 120
Query: 161 VDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVVNVCHRDIKPQNILVD 220
+ M L+Q ++ SL+ +Y +++Q+ + L Y+H NV HRD+KP N+L++
Sbjct: 121 FELMDTDLHQIIRSNQSLNDDHCQY----FLYQILRGLKYIHSA-NVLHRDLKPSNLLLN 175
Query: 221 PDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGATNYTTKIDIWSAGCVMAEL 280
+ L KI D G A+ E Y+ +R+YRAPEL+ ++ YT+ ID+WS GC+ AE+
Sbjct: 176 SNCDL-KITDFGLARTTSETEYMTEYVVTRWYRAPELLLNSSEYTSAIDVWSVGCIFAEI 234
Query: 281 LLGQPIFPGESKIDQLVEIIKVLGTP---TREEICSMNENYSEHKFPQIRPIPLNRIFKK 337
+ +P+FPG+ + QL I +++G+P + E + S N + P+ + F
Sbjct: 235 MTREPLFPGKDYVHQLKLITELIGSPDGASLEFLRSANARKYVKELPKFPRQNFSARFPS 294
Query: 338 ETQETIDLLYHIMKYDP 354
IDLL ++ +DP
Sbjct: 295 MNSTAIDLLEKMLVFDP 311
>At1g03740 [D] KOG0600 Cdc2-related protein kinase
Length = 542
Score = 131 bits (330), Expect = 2e-30
Identities = 95/298 (31%), Positives = 151/298 (49%), Gaps = 35/298 (11%)
Query: 91 EIVGNGSFGVVFRTKVKETGEDVVIKKV------LQDRRFKNRELEIMKLISHPNLIDLK 144
E +G G++ V+R + + V +KKV ++ +F RE+ +M+ + HPN++ L+
Sbjct: 217 EKIGQGTYSSVYRARDLLHNKIVALKKVRFDLNDMESVKFMAREIIVMRRLDHPNVLKLE 276
Query: 145 YYFLEQSDQELYLNLIVDYMPMSLYQRLK-EFISLHQPMDRYEIKIYMFQLFKSLNYLHQ 203
LYL + +YM L + +P ++K YM QL L + H
Sbjct: 277 GLITAPVSSSLYL--VFEYMDHDLLGLSSLPGVKFTEP----QVKCYMRQLLSGLEHCHS 330
Query: 204 VVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPN--VSYICSRYYRAPELIFGA 261
V HRDIK N+L+D +L KI D G A P + S++ + +YR PEL+ GA
Sbjct: 331 R-GVLHRDIKGSNLLIDSKGVL-KIADFGLATFFDPAKSVSLTSHVVTLWYRPPELLLGA 388
Query: 262 TNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENY-SE 320
++Y +D+WS GC++ EL G+PI PG+++++QL +I K+ G+PT ENY +
Sbjct: 389 SHYGVGVDLWSTGCILGELYAGKPILPGKTEVEQLHKIFKLCGSPT--------ENYWRK 440
Query: 321 HKFPQI----RPIPLNR----IFKKETQETIDLLYHIMKYDPNIRYSALQCMFNSTYF 370
K P IP R +FK + LL ++ DP+ R SA + + S YF
Sbjct: 441 QKLPSSAGFKTAIPYRRKVSEMFKDFPASVLSLLETLLSIDPDHRSSADRAL-ESEYF 497
>7297631 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 372
Score = 131 bits (330), Expect = 2e-30
Identities = 93/292 (31%), Positives = 150/292 (50%), Gaps = 36/292 (12%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN--------RELEIMKLISHPNLIDLK 144
+G+G+ G+V T ++V IKK+ R F+N RE ++MKL++H N+I L
Sbjct: 30 IGSGAQGIVCAAYDTITQQNVAIKKL--SRPFQNVTHAKRAYREFKLMKLVNHKNIIGLL 87
Query: 145 YYFLEQSDQELYLN--LIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLH 202
F Q + E + + L+++ M +L Q ++ +D + ++Q+ + +LH
Sbjct: 88 NAFTPQRNLEEFQDVYLVMELMDANLCQVIQ------MDLDHDRMSYLLYQMLCGIKHLH 141
Query: 203 QVVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGAT 262
+ HRD+KP NI+V D L KI D G A+ Y+ +RYYRAPE+I G
Sbjct: 142 SA-GIIHRDLKPSNIVVKADCTL-KILDFGLARTAGTTFMMTPYVVTRYYRAPEVILGM- 198
Query: 263 NYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPT---REEICSMNENYS 319
YT +DIWS GC+M E++ G +FPG IDQ +II+ LGTP+ + + NY
Sbjct: 199 GYTENVDIWSVGCIMGEMIRGGVLFPGTDHIDQWNKIIEQLGTPSPSFMQRLQPTVRNYV 258
Query: 320 EHK-----------FPQ-IRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYS 359
E++ FP + P N+ +++ + +LL ++ DP R S
Sbjct: 259 ENRPRYTGYSFDRLFPDGLFPNDNNQNSRRKASDARNLLSKMLVIDPEQRIS 310
>SPCC16C4.11 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 288
Score = 131 bits (329), Expect = 2e-30
Identities = 86/289 (29%), Positives = 155/289 (52%), Gaps = 16/289 (5%)
Query: 91 EIVGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN-----RELEIMKLISHPNLIDLKY 145
E +G G++ V++ + + TGE V +K + D RE+ +MK + HPN++ L
Sbjct: 7 EKLGEGTYAHVYKGQNRVTGEIVALKVIRIDADEGTPSTAIREISLMKELRHPNIMSLS- 65
Query: 146 YFLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVV 205
+ E L L+ +YM L + + + + + ++K + QL K +++ H+
Sbjct: 66 ---DVLQTENKLMLVFEYMEKDLKKYMDTYGN-QGALPPSQVKNFTQQLLKGISFCHEN- 120
Query: 206 NVCHRDIKPQNILVDPDTLLLKICDLGSAKQLK-PNEPNVSYICSRYYRAPELIFGATNY 264
V HRD+KPQN+L++ L K+ D G A+ + P + + + +YRAP+++ G+ Y
Sbjct: 121 RVLHRDLKPQNLLINSRGEL-KLADFGLARSIGIPVNTFSNEVVTLWYRAPDVLLGSRVY 179
Query: 265 TTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEI--CSMNENYSEHK 322
+T IDIWS GC+MAE+ G+P+F G + DQL++I ++LGTPT + S+ Y +
Sbjct: 180 STSIDIWSVGCIMAEMATGRPLFAGSNNEDQLLKIFRLLGTPTEQSWPGISLLPEY-KPT 238
Query: 323 FPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSALQCMFNSTYFT 371
FP + L +F +DLL +++ P +R + + ++ + T
Sbjct: 239 FPIYKAQDLAYLFPTFDPLGLDLLRRMLRLQPELRTTGQDALQHAWFLT 287
>Hs21040235 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 384
Score = 131 bits (329), Expect = 2e-30
Identities = 90/296 (30%), Positives = 157/296 (52%), Gaps = 21/296 (7%)
Query: 91 EIVGNGSFGVVFRTKVKETGEDVVIKKVLQDRR-----FKNRELEIMKLISHPNLIDLKY 145
E +G GS+ V++ + G+ V +K + + RE ++K + H N++ L +
Sbjct: 56 EKLGEGSYATVYKGISRINGQLVALKVISMNAEEGVPFTAIREASLLKGLKHANIV-LLH 114
Query: 146 YFLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVV 205
+ + L + +YM L Q + + P + ++++MFQL + L Y+H
Sbjct: 115 DIIHTKET---LTFVFEYMHTDLAQYMSQHPGGLHP---HNVRLFMFQLLRGLAYIHHQ- 167
Query: 206 NVCHRDIKPQNILVDPDTLLLKICDLGSAKQLK-PNEPNVSYICSRYYRAPELIFGATNY 264
+V HRD+KPQN+L+ LK+ D G A+ P++ S + + +YR P+ + GAT Y
Sbjct: 168 HVLHRDLKPQNLLIS-HLGELKLADFGLARAKSIPSQTYSSEVVTLWYRPPDALLGATEY 226
Query: 265 TTKIDIWSAGCVMAELLLGQPIFPGESKI-DQLVEIIKVLGTPTREEICSMNE--NYSEH 321
++++DIW AGC+ E+ GQP+FPG S I +QL +I +VLG PT + +++ NY+
Sbjct: 227 SSELDIWGAGCIFIEMFQGQPLFPGVSNILEQLEKIWEVLGVPTEDTWPGVSKLPNYNPE 286
Query: 322 KFPQIRPIPLNRIFKK--ETQETIDLLYHIMKYDPNIRYSALQCMFNSTYFTDIVS 375
FP P L+ ++ + E DL ++K P R SA + + + YF+ + S
Sbjct: 287 WFPLPTPRSLHVVWNRLGRVPEAEDLASQMLKGFPRDRVSAQEALVHD-YFSALPS 341
>CE21213 [UT] KOG0662 Cyclin-dependent kinase CDK5
Length = 292
Score = 131 bits (329), Expect = 2e-30
Identities = 94/291 (32%), Positives = 151/291 (51%), Gaps = 19/291 (6%)
Query: 91 EIVGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN------RELEIMKLISHPNLIDLK 144
E +G G++G VF+ + K +GE V +K+V D + RE+ I++ + H N++ L
Sbjct: 8 EKIGEGTYGTVFKARNKNSGEIVALKRVRLDDDDEGVPSSALREICILRELKHRNVVRL- 66
Query: 145 YYFLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQV 204
Y + S+ +L L+ +Y L K F SL+ MD + M QL + L++ H
Sbjct: 67 -YDVVHSENKL--TLVFEYCDQDLK---KFFDSLNGYMDAQTARSLMLQLLRGLSFCH-A 119
Query: 205 VNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLK-PNEPNVSYICSRYYRAPELIFGATN 263
+V HRD+KPQN+L++ + L K+ D G A+ P + + + +YR P+++FGA
Sbjct: 120 HHVLHRDLKPQNLLINTNGTL-KLADFGLARAFGVPVRCFSAEVVTLWYRPPDVLFGAKL 178
Query: 264 YTTKIDIWSAGCVMAELL-LGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENYSEHK 322
Y T ID+WSAGC+ AE+ G+P+FPG DQL I K LG+P+ + S+ +
Sbjct: 179 YNTSIDMWSAGCIFAEISNAGRPLFPGADVDDQLKRIFKQLGSPSEDNWPSITQLPDYKP 238
Query: 323 FPQIRP-IPLNRIFKKETQETIDLLYHIMKYDPNIRYSALQCMFNSTYFTD 372
+P P + ++I DLL ++ +P R A YF D
Sbjct: 239 YPIYHPTLTWSQIVPNLNSRGRDLLQKLLVCNPAGRIDA-DAALRHAYFAD 288
>CE18009 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 384
Score = 131 bits (329), Expect = 2e-30
Identities = 83/291 (28%), Positives = 151/291 (51%), Gaps = 27/291 (9%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN------RELEIMKLISHPNLIDL--- 143
+G G++GVVF+ +K + DR + RE+ +K + H N++ L
Sbjct: 51 IGEGTYGVVFKAIHVRDNVKCALKMIRTDRDEEGIPSTCLREISCIKDLQHDNIVTLFDI 110
Query: 144 ---------KYYFLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQL 194
F E+ L ++ +++ L L+ + + +K +M+QL
Sbjct: 111 IYASHFLNYNNIFFEKFSSNSKLYMVFEFIDRDLKNLLEMLEPTNSVLPPNYVKSFMWQL 170
Query: 195 FKSLNYLHQVVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLK-PNEPNVSYICSRYYR 253
+L+Y H + + HRD+KPQNILV D+ ++KI D G A+ P+ + + +YR
Sbjct: 171 LSALSYCH-LRRIVHRDLKPQNILVS-DSGVIKIADFGLARNFSFPSRNYTHEVVTLWYR 228
Query: 254 APELIFGATNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICS 313
PE++ G+ Y+T +D+WS GC+ +E+ +P+FPGE +I QL +I +++GTP +
Sbjct: 229 PPEILLGSQRYSTSLDMWSLGCIFSEIASNKPLFPGECEISQLFKIFEIVGTPNIKSWPG 288
Query: 314 MNENYSEHK--FPQIRPIPLNRIFKKE--TQETIDLLYHIMKYDPNIRYSA 360
+ +++ +K FPQ P+ L ++ + T +D+L I++Y P R +A
Sbjct: 289 V-DSFPHYKAVFPQ-WPVNLKKLEETSCLTGNGLDVLREILRYPPERRLTA 337
>At5g44290 [D] KOG0600 Cdc2-related protein kinase
Length = 644
Score = 131 bits (329), Expect = 2e-30
Identities = 93/297 (31%), Positives = 151/297 (50%), Gaps = 33/297 (11%)
Query: 91 EIVGNGSFGVVFRTKVKETGEDVVIKKV------LQDRRFKNRELEIMKLISHPNLIDLK 144
E +G G++ V++ + + V +K+V L+ +F RE+ +M+ + HPN++ L+
Sbjct: 141 EKIGQGTYSSVYKARDLTNNKIVALKRVRFDLSDLESVKFMAREIIVMRRLDHPNVLKLE 200
Query: 145 YYFLEQSDQELYLNLIVDYMPMSLYQRLK-EFISLHQPMDRYEIKIYMFQLFKSLNYLHQ 203
LYL + +YM L I +P ++K YM QL L++ H
Sbjct: 201 GLITASVSSSLYL--VFEYMDHDLVGLASIPGIKFSEP----QVKCYMQQLLSGLHHCHS 254
Query: 204 VVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNE--PNVSYICSRYYRAPELIFGA 261
V HRDIK N+L+D + +L KI D G A P P S + + +YR PEL+ GA
Sbjct: 255 R-GVLHRDIKGSNLLIDSNGVL-KIADFGLATFFDPQNCVPLTSRVVTLWYRPPELLLGA 312
Query: 262 TNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENYSEH 321
+Y +D+WS GC++ EL G+PI G+++++QL +I K+ G+PT + + +
Sbjct: 313 CHYGVGVDLWSTGCILGELYSGKPILAGKTEVEQLHKIFKLCGSPT-------EDYWRKL 365
Query: 322 KFP---QIRP-IPLNR----IFKKETQETIDLLYHIMKYDPNIRYSALQCMFNSTYF 370
K P RP +P R +FK + LL ++ DP+ R SA + + S YF
Sbjct: 366 KLPPSAAFRPALPYGRRVAEMFKDLPTNVLSLLEALLSIDPDRRGSAARAL-ESEYF 421
>At5g10270 [D] KOG0600 Cdc2-related protein kinase
Length = 505
Score = 131 bits (329), Expect = 2e-30
Identities = 94/304 (30%), Positives = 154/304 (49%), Gaps = 27/304 (8%)
Query: 91 EIVGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN------RELEIMKLISHPNLIDLK 144
E +G G++G V+ K +TGE V +KK+ D + RE++I+K + H N+I LK
Sbjct: 30 EQIGEGTYGQVYMAKEIKTGEIVALKKIRMDNEREGFPITAIREIKILKKLHHENVIQLK 89
Query: 145 YYFLE---------QSDQELY---LNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMF 192
+ D Y + ++ +YM L L + L + +IK YM
Sbjct: 90 EIVTSPGRDRDDQGKPDNNKYKGGIYMVFEYMDHDL-TGLADRPGLRFTVP--QIKCYMK 146
Query: 193 QLFKSLNYLHQVVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPN--VSYICSR 250
QL L+Y H V V HRDIK N+L+D + L K+ D G A+ + + + +
Sbjct: 147 QLLTGLHYCH-VNQVLHRDIKGSNLLIDNEGNL-KLADFGLARSYSHDHTGNLTNRVITL 204
Query: 251 YYRAPELIFGATNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREE 310
+YR PEL+ GAT Y ID+WS GC+ AELL +PI PG+++ +QL +I ++ G+P +
Sbjct: 205 WYRPPELLLGATKYGPAIDMWSVGCIFAELLHAKPILPGKNEQEQLNKIFELCGSPDEKL 264
Query: 311 ICSMNENYSEHKFPQIRPIP--LNRIFKKETQETIDLLYHIMKYDPNIRYSALQCMFNST 368
+++ + F RP+ + F+ + ++LL ++ DP R SA +
Sbjct: 265 WPGVSKMPWFNNFKPARPLKRRVREFFRHFDRHALELLEKMLVLDPAQRISAKDALDAEY 324
Query: 369 YFTD 372
++TD
Sbjct: 325 FWTD 328
>YPR161c [D] KOG0600 Cdc2-related protein kinase
Length = 657
Score = 130 bits (327), Expect = 4e-30
Identities = 101/344 (29%), Positives = 156/344 (44%), Gaps = 42/344 (12%)
Query: 57 VKIVPDEDEVITRRTVVKGHSNPEESVVISCGTPEIVGNGSFGVVFRTKVKETGEDVVIK 116
+K+ E + TV + H +E + G G+FG V++ ET V +K
Sbjct: 40 IKLRKRSSEKVYGCTVFQNHYREDEKL----------GQGTFGEVYKGIHLETQRQVAMK 89
Query: 117 KVLQDRR------FKNRELEIMKLISHPNLIDLKYYFLEQSDQELYLNLIVDYMPMSLYQ 170
K++ RE+ I+K ++H N+I L + S N + S Y
Sbjct: 90 KIIVSVEKDLFPITAQREITILKRLNHKNIIKLIEMVYDHSPD--ITNAASSNLHKSFYM 147
Query: 171 RLKEFIS-----LHQP---MDRYEIKIYMFQLFKSLNYLHQVVNVCHRDIKPQNILVDPD 222
L ++ LH P ++ +IK M Q+ + LNY+H HRDIK NIL+D +
Sbjct: 148 ILPYMVADLSGVLHNPRINLEMCDIKNMMLQILEGLNYIH-CAKFMHRDIKTANILIDHN 206
Query: 223 TLLLKICDLGSAKQLKPNEPNVSY-------------ICSRYYRAPELIFGATNYTTKID 269
+L K+ D G A+ PN+ Y + +R+YRAPEL+ G YTT +D
Sbjct: 207 GVL-KLADFGLARLYYGCPPNLKYPGGAGSGAKYTSVVVTRWYRAPELVLGDKQYTTAVD 265
Query: 270 IWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREE-ICSMNENYSEHKFPQIRP 328
IW GCV AE +PI G++ IDQ I K+LGTPT E+ + +E +P
Sbjct: 266 IWGVGCVFAEFFEKKPILQGKTDIDQGHVIFKLLGTPTEEDWAVARYLPGAELTTTNYKP 325
Query: 329 IPLNRIFKKETQETIDLLYHIMKYDPNIRYSALQCMFNSTYFTD 372
R K ++ +D L ++ DP R +A+ + + D
Sbjct: 326 TLRERFGKYLSETGLDFLGQLLALDPYKRLTAMSAKHHPWFKED 369
>SPAC3C7.06c [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 650
Score = 130 bits (327), Expect = 4e-30
Identities = 80/296 (27%), Positives = 153/296 (51%), Gaps = 30/296 (10%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKNREL-------EIMKLISHPNLIDLKY 145
VG+G+FG V+ K ++VV K ++ + K + +++L + N++++
Sbjct: 42 VGDGTFGSVYLATTKTPSKEVVAIKSMKKKLAKVSDATRLREVHSLLRLSENENIVNIFD 101
Query: 146 YFLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVV 205
++ DQ L+++++++ +LYQ + + P+ +++ M Q+FK LN++H
Sbjct: 102 LYI---DQFRCLHIVMEFLDCNLYQLIST--RKNDPLTLEQVQDIMRQIFKGLNHIH-TN 155
Query: 206 NVCHRDIKPQNILV----DPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGA 261
HRD+KP+NIL+ D + +KI D G A+++ P Y+ +R+YRAPEL+
Sbjct: 156 GFFHRDMKPENILISSNSDSSSFNVKIADFGLAREINSRPPYTEYVSTRWYRAPELLLRD 215
Query: 262 TNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTRE------------ 309
+ Y+ +DI++AGC+ E+ QPIFPG DQL ++ ++LG+P +
Sbjct: 216 SYYSFPVDIYAAGCMAFEIATLQPIFPGNDDFDQLYKMCEILGSPDEQSQNTGDKGGGIW 275
Query: 310 EICSMNENYSEHKFPQIRPIPLNRIFKKETQETI-DLLYHIMKYDPNIRYSALQCM 364
+ + N P++ P+ +F +L ++K+DP R +A C+
Sbjct: 276 DRAELLANKLGISLPKMAPLDFGDLFSPPWNLAFASMLSQLLKWDPAKRPTAEMCL 331
>CE27574 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 463
Score = 130 bits (327), Expect = 4e-30
Identities = 95/310 (30%), Positives = 152/310 (48%), Gaps = 40/310 (12%)
Query: 92 IVGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN--------RELEIMKLISHPNLIDL 143
++G+G+ G+V E V IKK+ R F+N REL++M L++H N+I +
Sbjct: 124 LIGSGAQGIVCSAFDTVRNEQVAIKKL--SRPFQNVTHAKRAYRELKLMSLVNHKNIIGI 181
Query: 144 KYYFLEQSDQELY--LNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYL 201
F Q + + L ++++ M +L Q ++ +D + ++Q+ + +L
Sbjct: 182 LNCFTPQKKLDEFNDLYIVMELMDANLCQVIQ------MDLDHERLSYLLYQMLCGIRHL 235
Query: 202 HQVVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGA 261
H + HRD+KP NI+V D L KI D G A+ Y+ +RYYRAPE+I G
Sbjct: 236 HSA-GIIHRDLKPSNIVVRSDCTL-KILDFGLARTAIEAFMMTPYVVTRYYRAPEVILGM 293
Query: 262 TNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTR---EEICSMNENY 318
Y +D+WS GC+ EL+ G+ +FPG IDQ II+ LGTP R E + NY
Sbjct: 294 -GYKENVDVWSIGCIFGELIRGRVLFPGGDHIDQWTRIIEQLGTPDRSFLERLQPTVRNY 352
Query: 319 SEHKFPQIRPIPLNRIFKKET------------QETIDLLYHIMKYDPNIRYS---ALQC 363
E++ P+ + P +F + DLL ++ DP R S AL+
Sbjct: 353 VENR-PRYQATPFEVLFSDNMFPMTADSSRLTGAQARDLLSRMLVIDPERRISVDDALRH 411
Query: 364 MFNSTYFTDI 373
+ + +F +I
Sbjct: 412 PYVNVWFDEI 421
>SPBC32H8.10 [D] KOG0600 Cdc2-related protein kinase
Length = 591
Score = 130 bits (326), Expect = 5e-30
Identities = 95/309 (30%), Positives = 155/309 (49%), Gaps = 36/309 (11%)
Query: 91 EIVGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN------RELEIMKLISHPNLIDLK 144
E +G G+FG V++++ ++ G+ +K++L + RE++I+K I H N+I L
Sbjct: 40 EKLGEGTFGEVYKSQRRKDGKVYALKRILMHTEKEGFPITAIREIKILKSIKHENIIPLS 99
Query: 145 YYFLEQSDQELY----LNLIVDYMPMSLYQRLKE-FISLHQPMDRYEIKIYMFQLFKSLN 199
+ ++D++ + ++ YM L L+ + +P +IK YM QLF
Sbjct: 100 DMTVVRADKKHRRRGSIYMVTPYMDHDLSGLLENPSVKFTEP----QIKCYMKQLFAGTK 155
Query: 200 YLHQVVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNE----------PN----VS 245
YLH + + HRD+K N+L+D +L KI D G A+ + PN
Sbjct: 156 YLHDQL-ILHRDLKAANLLIDNHGIL-KIADFGLARVITEESYANKNPGLPPPNRREYTG 213
Query: 246 YICSRYYRAPELIFGATNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGT 305
+ +R+YR+PEL+ G YTT ID+WS GC+MAE+ G+PI G S +DQL +I ++ G+
Sbjct: 214 CVVTRWYRSPELLLGERRYTTAIDMWSVGCIMAEMYKGRPILQGSSDLDQLDKIFRLCGS 273
Query: 306 PTREEICSMNE---NYSEHKFPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSALQ 362
PT+ + + + FP P L F +E L I+ +P+ R SA
Sbjct: 274 PTQATMPNWEKLPGCEGVRSFPS-HPRTLETAFFTFGKEMTSLCGAILTLNPDERLSASM 332
Query: 363 CMFNSTYFT 371
+ YFT
Sbjct: 333 AL-EHEYFT 340
>Hs20986512 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 129 bits (325), Expect = 6e-30
Identities = 86/290 (29%), Positives = 149/290 (50%), Gaps = 24/290 (8%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN--------RELEIMKLISHPNLIDLK 144
VG+G++G V +TG V +KK+ R F++ REL ++K + H N+I L
Sbjct: 30 VGSGAYGSVCAAFDTKTGLRVAVKKL--SRPFQSIIHAKRTYRELRLLKHMKHENVIGLL 87
Query: 145 YYFLEQSDQELY--LNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLH 202
F E + + L+ M L +K Q + ++ ++Q+ + L Y+H
Sbjct: 88 DVFTPARSLEEFNDVYLVTHLMGADLNNIVK-----CQKLTDDHVQFLIYQILRGLKYIH 142
Query: 203 QVVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGAT 262
++ HRD+KP N+ V+ D L KI D G A+ ++ Y+ +R+YRAPE++
Sbjct: 143 SA-DIIHRDLKPSNLAVNEDCEL-KILDFGLARHT--DDEMTGYVATRWYRAPEIMLNWM 198
Query: 263 NYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENYSEHK 322
+Y +DIWS GC+MAELL G+ +FPG IDQL I++++GTP E + ++ + +
Sbjct: 199 HYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKISSESARNY 258
Query: 323 FPQIRPIP---LNRIFKKETQETIDLLYHIMKYDPNIRYSALQCMFNSTY 369
+ +P +F +DLL ++ D + R +A Q + ++ +
Sbjct: 259 IQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQALAHAYF 308
>At1g71530 [D] KOG0600 Cdc2-related protein kinase
Length = 655
Score = 129 bits (325), Expect = 6e-30
Identities = 79/226 (34%), Positives = 129/226 (56%), Gaps = 17/226 (7%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVL------QDRRFKNRELEIMKLISHPNLIDLKYY 146
+G G++ V++ + ETG+ V +KKV + RF RE+ I++ + HPN++ L+
Sbjct: 153 IGQGTYSSVYKARDLETGKIVAMKKVRFVNMDPESVRFMAREILILRKLDHPNVMKLEGL 212
Query: 147 FLEQSDQELYLNLIVDYMPMSLYQ-RLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVV 205
+ LYL + +YM L I +P +IK YM QLF+ L + H+
Sbjct: 213 VTSRLSGSLYL--VFEYMEHDLAGLAATPGIKFSEP----QIKCYMQQLFRGLEHCHRR- 265
Query: 206 NVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPN--VSYICSRYYRAPELIFGATN 263
+ HRDIK N+L++ + +L KI D G A + + S + + +YRAPEL+ GAT
Sbjct: 266 GILHRDIKGSNLLINNEGVL-KIGDFGLANFYRGDGDLQLTSRVVTLWYRAPELLLGATE 324
Query: 264 YTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTRE 309
Y ID+WSAGC++ EL G+PI PG ++++Q+ +I K+ G+P+ +
Sbjct: 325 YGPAIDLWSAGCILTELFAGKPIMPGRTEVEQMHKIFKLCGSPSED 370
>YPL031c [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 305
Score = 129 bits (324), Expect = 8e-30
Identities = 86/289 (29%), Positives = 155/289 (52%), Gaps = 22/289 (7%)
Query: 91 EIVGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN-----RELEIMKLISHPNLIDLKY 145
E +GNG++ V++ K TG V +K+V D RE+ +MK + H N++ L
Sbjct: 11 EKLGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHENIVRL-- 68
Query: 146 YFLEQSDQELYLNLIVDYMPMSL--YQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQ 203
+ E L L+ ++M L Y + + + ++ +K + +QL + L + H+
Sbjct: 69 --YDVIHTENKLTLVFEFMDNDLKKYMDSRTVGNTPRGLELNLVKYFQWQLLQGLAFCHE 126
Query: 204 VVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLK-PNEPNVSYICSRYYRAPELIFGAT 262
+ HRD+KPQN+L++ L K+ D G A+ P S + + +YRAP+++ G+
Sbjct: 127 N-KILHRDLKPQNLLINKRGQL-KLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSR 184
Query: 263 NYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNE--NYSE 320
Y+T IDIWS GC++AE++ G+P+FPG + +QL I ++GTP S+ + Y+
Sbjct: 185 TYSTSIDIWSCGCILAEMITGKPLFPGTNDEEQLKLIFDIMGTPNESLWPSVTKLPKYNP 244
Query: 321 HKFPQIRPIPLNRIFKKETQETI-----DLLYHIMKYDPNIRYSALQCM 364
+ Q P L ++ + T+E + D L+ +++ +P++R SA Q +
Sbjct: 245 N-IQQRPPRDLRQVLQPHTKEPLDGNLMDFLHGLLQLNPDMRLSAKQAL 292
>CE29612 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 426
Score = 129 bits (324), Expect = 8e-30
Identities = 84/293 (28%), Positives = 151/293 (50%), Gaps = 30/293 (10%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN-------RELEIMKLISHPNLIDLKY 145
+G GS+ V++ + K G V +K++ +F+ RE +++ + H N++ L
Sbjct: 114 LGEGSYATVYKCESKLDGSIVALKEI--KLQFQEGLPFTAIREASLLRNLRHANIVSLHD 171
Query: 146 YFLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVV 205
F + L + +YM M L + L++ + +D +IK+ +FQL + L++ H+
Sbjct: 172 IFYQHHQ----LTFVFEYMKMDLSKYLEQNV---YGLDSIDIKLLLFQLLRGLDFCHRK- 223
Query: 206 NVCHRDIKPQNILVDPDTLLLKICDLGSAKQLK-PNEPNVSYICSRYYRAPELIFGATNY 264
+ HRD+KPQN+L+D D +L K+ D G A+ P+ + + +YR P+++ G+T+Y
Sbjct: 224 KILHRDLKPQNLLLDEDGVL-KLADFGLARAKSVPSRTYSHEVVTLWYRPPDVLMGSTDY 282
Query: 265 TTKIDIWSAGCVMAELLLGQPIFPGESKI------DQLVEIIKVLGTPTREEICSMN--E 316
+T +D+W GC+ AE+ G +FPG DQL I + GTP ++ +
Sbjct: 283 STSLDMWGVGCIFAEICTGAALFPGSKDSHYPGTKDQLDMIFSIRGTPDEKKWPEVKTLP 342
Query: 317 NYSEHKFPQIRP---IPLNRIFKKETQETIDLLYHIMKYDPNIRYSALQCMFN 366
Y+ FP+ R I +N +F K + +LL +++ P R SA M +
Sbjct: 343 GYTPELFPRYRELSFIAVNPMFTKILKTGQELLGMLLQLRPESRVSAASAMLH 395
>7301110 [T] KOG0660 Mitogen-activated protein kinase
Length = 366
Score = 129 bits (323), Expect = 1e-29
Identities = 90/284 (31%), Positives = 142/284 (49%), Gaps = 19/284 (6%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN--------RELEIMKLISHPNLIDLK 144
VG+G++G V + V+ T V IKK+ R F++ REL ++K + H N+I L
Sbjct: 31 VGSGAYGQVSKAVVRGTNMHVAIKKLA--RPFQSAVHAKRTYRELRLLKHMDHENVIGLL 88
Query: 145 YYFLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQV 204
F N Y+ L I Q + ++ ++Q+ + L Y+H
Sbjct: 89 DIFHPHPANGSLENFQQVYLVTHLMDADLNNIIRMQHLSDDHVQFLVYQILRGLKYIHSA 148
Query: 205 VNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVS-YICSRYYRAPELIFGATN 263
V HRD+KP NI V+ D L +I D G A+ P E ++ Y+ +R+YRAPE++ +
Sbjct: 149 -GVIHRDLKPSNIAVNEDCEL-RILDFGLAR---PTENEMTGYVATRWYRAPEIMLNWMH 203
Query: 264 YTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTRE---EICSMNENYSE 320
Y +DIWS GC+MAEL+ + +FPG I QL I+++LGTP E +I S +
Sbjct: 204 YDQTVDIWSVGCIMAELITRRTLFPGTDHIHQLNLIMEMLGTPPAEFLKKISSESARSYI 263
Query: 321 HKFPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSALQCM 364
P ++ +FK IDLL +++ D R +A + +
Sbjct: 264 QSLPPMKGRSFKNVFKNANPLAIDLLEKMLELDAEKRITAEEAL 307
>Hs4506091 [T] KOG0660 Mitogen-activated protein kinase
Length = 721
Score = 128 bits (322), Expect = 1e-29
Identities = 81/294 (27%), Positives = 155/294 (52%), Gaps = 30/294 (10%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVL----QDRRFKNRELEIMKLISHPNLIDLKYYFL 148
+G G G+VF + + V IKK++ Q + RE++I++ + H N++ + + L
Sbjct: 26 LGCGGNGLVFSAVDNDCDKRVAIKKIVLTDPQSVKHALREIKIIRRLDHDNIVKV-FEIL 84
Query: 149 EQSDQELY-----------LNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKS 197
S +L + ++ +YM L L++ P+ +++M+QL +
Sbjct: 85 GPSGSQLTDDVGSLTELNSVYIVQEYMETDLANVLEQ-----GPLLEEHARLFMYQLLRG 139
Query: 198 LNYLHQVVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYIC----SRYYR 253
L Y+H NV HRD+KP N+ ++ + L+LKI D G A+ + P+ + ++ +++YR
Sbjct: 140 LKYIHSA-NVLHRDLKPANLFINTEDLVLKIGDFGLARIMDPHYSHKGHLSEGLVTKWYR 198
Query: 254 APELIFGATNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQ---LVEIIKVLGTPTREE 310
+P L+ NYT ID+W+AGC+ AE+L G+ +F G +++Q ++E I V+ R+E
Sbjct: 199 SPRLLLSPNNYTKAIDMWAAGCIFAEMLTGKTLFAGAHELEQMQLILESIPVVHEEDRQE 258
Query: 311 ICSMNENYSEHKFPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSALQCM 364
+ S+ Y + + PL ++ ++E +D L I+ + P R +A + +
Sbjct: 259 LLSVIPVYIRNDMTEPHK-PLTQLLPGISREALDFLEQILTFSPMDRLTAEEAL 311
>CE01761 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 719
Score = 127 bits (320), Expect = 2e-29
Identities = 84/295 (28%), Positives = 157/295 (52%), Gaps = 22/295 (7%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN------RELE-IMKLISHPNLIDLKY 145
V G+FGVV+R K K T E V +K++ ++ + RE+ ++K +HPN++++K
Sbjct: 362 VDEGTFGVVYRGKDKRTDEIVALKRLKMEKEKEGFPITALREINMLLKAGNHPNIVNVKE 421
Query: 146 YFLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVV 205
L + ++Y+ + +++ + L ++ E K + QL + ++H++
Sbjct: 422 ILLGSNMDKIYMAM--EFVEHDMKSLLDTMSRRNKRFSIGEQKTLLQQLLSGIEHMHKLW 479
Query: 206 NVCHRDIKPQNILVDPDTLLLKICDLGSAKQL-KPNEPNVSYICSRYYRAPELIFGATNY 264
+ HRD+K N+L+ +L KI D G A++ P + S + + +YR+PEL+ G Y
Sbjct: 480 -ILHRDLKTSNLLMSHKGIL-KIADFGLAREYGDPLKKFTSIVVTLWYRSPELLLGTRLY 537
Query: 265 TTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNE-------N 317
+T +D+WS GC+MAE +L +P+FPG +++Q+ +I +GTPT + E
Sbjct: 538 STPVDMWSVGCIMAEFILLKPLFPGRGELEQIKKIFMEMGTPTESIWPGVTELDGWKALT 597
Query: 318 YSEHKFPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSALQCMFNSTYFTD 372
+ ++ + Q+R L +T LL ++ DP R+SA Q + + +FT+
Sbjct: 598 FEKYPYNQLRKRFLAGRLLNDT--GFKLLNGLLTLDPKNRFSATQAL-DHEWFTE 649
>At1g09600 [D] KOG0600 Cdc2-related protein kinase
Length = 714
Score = 127 bits (320), Expect = 2e-29
Identities = 80/227 (35%), Positives = 125/227 (54%), Gaps = 15/227 (6%)
Query: 91 EIVGNGSFGVVFRTKVKETGEDVVIKKVL------QDRRFKNRELEIMKLISHPNLIDLK 144
E +G G++ V++ + ET + V +KKV RF RE+ I++ + HPN++ L+
Sbjct: 167 EKIGQGTYSSVYKARDLETNQLVALKKVRFANMDPDSVRFMAREIIILRRLDHPNVMKLE 226
Query: 145 YYFLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQV 204
+ +YL I +YM L L ++ +IK YM QL L + H
Sbjct: 227 GLITSRVSGSMYL--IFEYMEHDL-AGLASTPGIN--FSEAQIKCYMKQLLHGLEHCHSR 281
Query: 205 VNVCHRDIKPQNILVDPDTLLLKICDLGSAK--QLKPNEPNVSYICSRYYRAPELIFGAT 262
V HRDIK N+L+D + L KI D G A Q +P S + + +YR PEL+ G+T
Sbjct: 282 -GVLHRDIKGSNLLLDHNNNL-KIGDFGLANFYQGHQKQPLTSRVVTLWYRPPELLLGST 339
Query: 263 NYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTRE 309
+Y +D+WS GC++AEL G+PI PG ++++QL +I K+ G+P+ E
Sbjct: 340 DYGVTVDLWSTGCILAELFTGKPIMPGRTEVEQLHKIFKLCGSPSEE 386
>Hs4503069 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 127 bits (319), Expect = 3e-29
Identities = 86/290 (29%), Positives = 148/290 (50%), Gaps = 24/290 (8%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN--------RELEIMKLISHPNLIDLK 144
VG+G++G V +TG V +KK+ R F++ REL ++K + H N+I L
Sbjct: 30 VGSGAYGSVCAAFDTKTGLRVAVKKL--SRPFQSIIHAKRTYRELRLLKHMKHENVIGLL 87
Query: 145 YYFLEQSDQELY--LNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLH 202
F E + + L+ M L +K Q + ++ ++Q+ + L Y+H
Sbjct: 88 DVFTPARSLEEFNDVYLVTHLMGADLNNIVK-----CQKLTDDHVQFLIYQILRGLKYIH 142
Query: 203 QVVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGAT 262
++ HRD+KP N+ V+ D L KI D G A+ ++ Y+ +R+YRAPE++
Sbjct: 143 SA-DIIHRDLKPSNLAVNEDCEL-KILDFGLARHT--DDEMTGYVATRWYRAPEIMLNWM 198
Query: 263 NYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENYSEHK 322
+Y +DIWS GC+MAELL G+ +FPG I+QL +I+++ GTP I M + + +
Sbjct: 199 HYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLQQIMRLTGTPPAYLINRMPSHEARNY 258
Query: 323 FPQIRPIP---LNRIFKKETQETIDLLYHIMKYDPNIRYSALQCMFNSTY 369
+ +P +F +DLL ++ D + R +A Q + ++ +
Sbjct: 259 IQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQALAHAYF 308
>SPBC18H10.15 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 398
Score = 127 bits (318), Expect = 4e-29
Identities = 88/302 (29%), Positives = 154/302 (50%), Gaps = 41/302 (13%)
Query: 91 EIVGNGSFGVVFRTKVKETGEDVVIKKVLQDRR------FKNRELEIMKLISHPNLIDLK 144
E + GS+G+V+R K T V +KK+ D RE+E + I H N+++L+
Sbjct: 78 EKIEEGSYGIVYRGLDKSTNTLVALKKIKFDPNGIGFPITSLREIESLSSIRHDNIVELE 137
Query: 145 YYFLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQV 204
+ + +++YL ++++M L L ++ + + E+K M QL + ++H
Sbjct: 138 KVVVGKDLKDVYL--VMEFMEHDLKTLLD---NMPEDFLQSEVKTLMLQLLAATAFMHHH 192
Query: 205 VNVCHRDIKPQNILVDPDTLLLKICDLGSAKQL-KPNEPNVSYICSRYYRAPELIFGATN 263
+ HRD+KP N+L++ +T +K+ D G A+ + +P + + +YRAPEL+ GA +
Sbjct: 193 WYL-HRDLKPSNLLMN-NTGEIKLADFGLARPVSEPKSSLTRLVVTLWYRAPELLLGAPS 250
Query: 264 YTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENYSEHKF 323
Y +ID+WS GC+ AE++ P+F G+S++DQL +I +LG PTREE +
Sbjct: 251 YGKEIDMWSIGCIFAEMITRTPLFSGKSELDQLYKIFNLLGYPTREE------------W 298
Query: 324 PQIRPIPLNRIFKKETQET---------------IDLLYHIMKYDPNIRYSALQCMFNST 368
PQ +P K T T DLL ++ +P R SA + + +
Sbjct: 299 PQYFLLPYANKIKHPTVPTHSKIRTSIPNLTGNAYDLLNRLLSLNPAKRISAKEALEHPY 358
Query: 369 YF 370
++
Sbjct: 359 FY 360
>Hs6912584 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 451
Score = 126 bits (317), Expect = 5e-29
Identities = 100/366 (27%), Positives = 182/366 (49%), Gaps = 25/366 (6%)
Query: 38 PSDDLKQGSLHSKNSHGNDVKI--VPDEDEVITRRTVVKGHSNPEESVVISCGTPEIVGN 95
P++ +K+ +HS+N+ + K E + R + ++P+ S E +G
Sbjct: 68 PANQVKR--VHSENNACINFKTSSTGKESPKVRRHSSPSSPTSPKFGKADSYEKLEKLGE 125
Query: 96 GSFGVVFRTKVKETGEDVVIKKV-LQDRRFKN----RELEIMKLISHPNLIDLKYYFLEQ 150
GS+ V++ K K G+ V +K + LQ+ RE ++K + H N++ L + +
Sbjct: 126 GSYATVYKGKSKVNGKLVALKVIRLQEEEGTPFTAIREASLLKGLKHANIV-LLHDIIHT 184
Query: 151 SDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVVNVCHR 210
+ L L+ +Y+ L Q + + P + +K+++FQL + L+Y+HQ + HR
Sbjct: 185 KET---LTLVFEYVHTDLCQYMDKHPGGLHPDN---VKLFLFQLLRGLSYIHQRY-ILHR 237
Query: 211 DIKPQNILVDPDTLLLKICDLGSAKQLK-PNEPNVSYICSRYYRAPELIFGATNYTTKID 269
D+KPQN+L+ DT LK+ D G A+ P+ + + + +YR P+++ G+T Y+T +D
Sbjct: 238 DLKPQNLLIS-DTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYSTCLD 296
Query: 270 IWSAGCVMAELLLGQPIFPGESKI-DQLVEIIKVLGTPTREEICSMNE--NYSEHKFPQI 326
+W GC+ E++ G FPG I DQL I VLGTP + ++ ++ +F
Sbjct: 297 MWGVGCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGVHSLPHFKPERFTLY 356
Query: 327 RPIPLNRIFKK--ETQETIDLLYHIMKYDPNIRYSALQCMFNSTYFTDIVSNTGSDSNLS 384
L + + K DL +++ P R SA Q + YF+D+ +++S
Sbjct: 357 SSKNLRQAWNKLSYVNHAEDLASKLLQCSPKNRLSA-QAALSHEYFSDLPPRLWELTDMS 415
Query: 385 LIDSLP 390
I ++P
Sbjct: 416 SIFTVP 421
>Hs4506081 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 422
Score = 126 bits (316), Expect = 7e-29
Identities = 92/291 (31%), Positives = 146/291 (49%), Gaps = 35/291 (12%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN--------RELEIMKLISHPNLIDLK 144
+G+G+ G+V +V IKK+ R F+N REL +MK ++H N+I L
Sbjct: 70 IGSGAQGIVCAAYDAVLDRNVAIKKL--SRPFQNQTHAKRAYRELVLMKCVNHKNIISLL 127
Query: 145 YYFLEQSDQELYLN--LIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLH 202
F Q E + + L+++ M +L Q ++ +D + ++Q+ + +LH
Sbjct: 128 NVFTPQKTLEEFQDVYLVMELMDANLCQVIQ------MELDHERMSYLLYQMLCGIKHLH 181
Query: 203 QVVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGAT 262
+ HRD+KP NI+V D L KI D G A+ + Y+ +RYYRAPE+I G
Sbjct: 182 SA-GIIHRDLKPSNIVVKSDCTL-KILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGM- 238
Query: 263 NYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMN---ENYS 319
Y +DIWS GC+M E++ + +FPG IDQ ++I+ LGTP E + + NY
Sbjct: 239 GYKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRNYV 298
Query: 320 EHK-------FPQIRPIPL----NRIFKKETQETIDLLYHIMKYDPNIRYS 359
E++ FP++ P L + K + + DLL ++ DP R S
Sbjct: 299 ENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRIS 349
>Hs20986510 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 464
Score = 126 bits (316), Expect = 7e-29
Identities = 92/291 (31%), Positives = 146/291 (49%), Gaps = 35/291 (12%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN--------RELEIMKLISHPNLIDLK 144
+G+G+ G+V +V IKK+ R F+N REL +MK ++H N+I L
Sbjct: 70 IGSGAQGIVCAAYDAVLDRNVAIKKL--SRPFQNQTHAKRAYRELVLMKCVNHKNIISLL 127
Query: 145 YYFLEQSDQELYLN--LIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLH 202
F Q E + + L+++ M +L Q ++ +D + ++Q+ + +LH
Sbjct: 128 NVFTPQKTLEEFQDVYLVMELMDANLCQVIQ------MELDHERMSYLLYQMLCGIKHLH 181
Query: 203 QVVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGAT 262
+ HRD+KP NI+V D L KI D G A+ + Y+ +RYYRAPE+I G
Sbjct: 182 SA-GIIHRDLKPSNIVVKSDCTL-KILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGM- 238
Query: 263 NYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMN---ENYS 319
Y +DIWS GC+M E++ + +FPG IDQ ++I+ LGTP E + + NY
Sbjct: 239 GYKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRNYV 298
Query: 320 EHK-------FPQIRPIPL----NRIFKKETQETIDLLYHIMKYDPNIRYS 359
E++ FP++ P L + K + + DLL ++ DP R S
Sbjct: 299 ENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRIS 349
>Hs20986506 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 426
Score = 126 bits (316), Expect = 7e-29
Identities = 92/291 (31%), Positives = 146/291 (49%), Gaps = 35/291 (12%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN--------RELEIMKLISHPNLIDLK 144
+G+G+ G+V +V IKK+ R F+N REL +MK ++H N+I L
Sbjct: 32 IGSGAQGIVCAAYDAVLDRNVAIKKL--SRPFQNQTHAKRAYRELVLMKCVNHKNIISLL 89
Query: 145 YYFLEQSDQELYLN--LIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLH 202
F Q E + + L+++ M +L Q ++ +D + ++Q+ + +LH
Sbjct: 90 NVFTPQKTLEEFQDVYLVMELMDANLCQVIQ------MELDHERMSYLLYQMLCGIKHLH 143
Query: 203 QVVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGAT 262
+ HRD+KP NI+V D L KI D G A+ + Y+ +RYYRAPE+I G
Sbjct: 144 SA-GIIHRDLKPSNIVVKSDCTL-KILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGM- 200
Query: 263 NYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMN---ENYS 319
Y +DIWS GC+M E++ + +FPG IDQ ++I+ LGTP E + + NY
Sbjct: 201 GYKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRNYV 260
Query: 320 EHK-------FPQIRPIPL----NRIFKKETQETIDLLYHIMKYDPNIRYS 359
E++ FP++ P L + K + + DLL ++ DP R S
Sbjct: 261 ENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRIS 311
>Hs20502986 [T] KOG0660 Mitogen-activated protein kinase
Length = 277
Score = 126 bits (316), Expect = 7e-29
Identities = 75/248 (30%), Positives = 136/248 (54%), Gaps = 30/248 (12%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN------RELEIMKLIS-HPNLIDLKY 145
+G G++G+V++ + TGE V IKK+ R K RE+ +++ HPN+I L
Sbjct: 19 LGQGAYGIVWKAVDRRTGEVVAIKKIFDAFRDKTDAQRTFREITLLQEFGDHPNIISLLD 78
Query: 146 YFLEQSDQELYLNLIVDYM-------PMSLYQRLKEFISLHQPMDR------YEIKIYMF 192
++D+++YL + ++M P + + L L+ + + ++ +
Sbjct: 79 VIRAENDRDIYL--VFEFMGCPPSPPPPTAVRTLSADTDLNAVIRKGGLLQDVHVRSIFY 136
Query: 193 QLFKSLNYLHQVVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLK--PNEPN----VSY 246
QL ++ +LH +V HRD KP N+L+D + + K+CD G A+ L P P Y
Sbjct: 137 QLLRATRFLHSG-HVVHRDQKPSNVLLDANCTV-KLCDFGLARSLGDLPEGPEDQAVTEY 194
Query: 247 ICSRYYRAPELIFGATNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTP 306
+ +R+YRAPE++ + YT +D+WS GC++ E+L G+P+FPG S + QL I++ + P
Sbjct: 195 VATRWYRAPEVLLSSHRYTLGVDMWSLGCILGEMLRGRPLFPGTSTLHQLELILETIPPP 254
Query: 307 TREEICSM 314
+ E++ ++
Sbjct: 255 SEEDLLAL 262
>CE03811 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 763
Score = 125 bits (314), Expect = 1e-28
Identities = 82/310 (26%), Positives = 166/310 (53%), Gaps = 27/310 (8%)
Query: 73 VKGHSNPEESVVISCGTPEIVGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN------ 126
++G + E V+++ ++ G++G VFR K T E V +K+ ++ +
Sbjct: 390 LRGCQHISEYVILN-----VIAEGTYGEVFRGKNTRTDEVVALKRFKMEKEKEGFPITAL 444
Query: 127 RELE-IMKLISHPNLIDLKYYFLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRY 185
RE+ ++K +H N++++K + + E+Y+ + +Y+ + + + S +Q
Sbjct: 445 REINMLLKAGAHENIVNVKEILVGSTKTEVYMAM--EYVEHDVKSLIDKMRSRNQRFKTG 502
Query: 186 EIKIYMFQLFKSLNYLHQVVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQ------LKP 239
+ K M QL + ++H++ + HRD+K N+L+ +L KI D G A++ ++
Sbjct: 503 QQKTLMSQLLSGIEHMHKLW-ILHRDLKTSNLLISHSGIL-KIADFGLAREYGEARDIEK 560
Query: 240 NEPNVSYICSRYYRAPELIFGATNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEI 299
+ + +YR+PEL+ Y+T +D+WS GC+MAE ++ +P+F G+S+ +Q+ +I
Sbjct: 561 RMKLTPIVVTLWYRSPELLLEPKTYSTPVDMWSIGCIMAEFIMMKPMFQGDSEPNQVHQI 620
Query: 300 IKVLGTPTREEICSMNE--NYSEHKFPQIRPIPLNRIFKKE---TQETIDLLYHIMKYDP 354
+++GTPT + + E ++ +FP ++P L RIFK E + DLL ++ +P
Sbjct: 621 FQMMGTPTEQIWPDIKELKVWNMVEFPPVKPGQLRRIFKGEKLVNETGFDLLNGMLCLNP 680
Query: 355 NIRYSALQCM 364
R +A + +
Sbjct: 681 ANRLTASEAL 690
>Hs4503095 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 391
Score = 124 bits (311), Expect = 3e-28
Identities = 85/298 (28%), Positives = 150/298 (49%), Gaps = 35/298 (11%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIK--KVLQDRRFKNRELEIMK-LISHPNLIDLKYYFLE 149
+G G + VF E VV+K K ++ ++ K RE++I++ L PN+I L +
Sbjct: 45 LGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIK-REIKILENLRGGPNIITLADIVKD 103
Query: 150 QSDQELYLNLIVDYMPMSLYQRLK--EFISLHQPMDRYEIKIYMFQLFKSLNYLHQVVNV 207
V P +++ + +F L+Q + Y+I+ YM+++ K+L+Y H + +
Sbjct: 104 P----------VSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSM-GI 152
Query: 208 CHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGATNYTTK 267
HRD+KP N+++D + L++ D G A+ P + + SRY++ PEL+ Y
Sbjct: 153 MHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYS 212
Query: 268 IDIWSAGCVMAELLL-GQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENYSEHKFPQI 326
+D+WS GC++A ++ +P F G DQLV I KVLGT E++ + Y+ P+
Sbjct: 213 LDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGT---EDLYDYIDKYNIELDPRF 269
Query: 327 RPIPLNRIFKKE-------------TQETIDLLYHIMKYDPNIRYSALQCMFNSTYFT 371
I L R +K + E +D L +++YD R +A + M + ++T
Sbjct: 270 NDI-LGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYT 326
>CE11556 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 305
Score = 124 bits (311), Expect = 3e-28
Identities = 74/227 (32%), Positives = 119/227 (51%), Gaps = 33/227 (14%)
Query: 89 TPEIVGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFK---NRELEIMKLISHPNLIDLKY 145
T ++ G G+FG+V + T + V IK+++ K RE+ ++ + H N++ L
Sbjct: 10 TIQVAGRGAFGLVVIARDTLTSKRVAIKRIMVPNVSKVSLAREISCLRNLHHRNILKLLD 69
Query: 146 YFLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVV 205
F ++++ + +P + Y Q+ + YLH
Sbjct: 70 CFPSAD----LMSIVTEEVPYTWYYT---------------------QILSGIAYLHSK- 103
Query: 206 NVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSY---ICSRYYRAPELIFGAT 262
+ HRDIKP+NILV ++ KI D G A P +PN Y + +R+YRAPEL+FG+
Sbjct: 104 EIMHRDIKPENILVTSRNVV-KIADFGQACFYMPKDPNQEYDVNVATRWYRAPELLFGSK 162
Query: 263 NYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTRE 309
Y +DIW+ GC++AEL+ G+PIFPG S+++Q+ I VLGTP +
Sbjct: 163 KYKPDVDIWAIGCILAELVRGKPIFPGRSELEQISIIFGVLGTPNED 209
>At2g23080 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 333
Score = 124 bits (311), Expect = 3e-28
Identities = 87/297 (29%), Positives = 150/297 (50%), Gaps = 30/297 (10%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIK--KVLQDRRFKNRELEIMK-LISHPNLIDLKYYFLE 149
VG G + VF K T E VIK K ++ ++ K RE++I++ L PN++ K Y +
Sbjct: 40 VGRGKYSEVFEGKNVNTNERCVIKILKPVKKKKIK-REIKILQNLCGGPNIV--KLYDIV 96
Query: 150 QSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVVNVCH 209
+ + +L+ +++ +F L+ + Y+I+ Y+++L K+L++ H + H
Sbjct: 97 RDEHSKTPSLVFEFV------NSVDFKVLYPTLTDYDIRYYIYELLKALDFCHSQ-GIMH 149
Query: 210 RDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGATNYTTKID 269
RD+KP N+++D L++ D G A+ P + + SRY++ PEL+ +Y +D
Sbjct: 150 RDVKPHNVMIDHQLRKLRLIDWGLAEFYHPGKEYNVRVASRYFKGPELLVDLQDYDYSLD 209
Query: 270 IWSAGCVMAELLL-GQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENYSEHKFPQIR- 327
+WS GC+ A ++ +P F G DQLV+I KVLGT E+ Y PQ+
Sbjct: 210 MWSLGCMFAGMIFRKEPFFYGHDNHDQLVKIAKVLGT---NELDHYLNKYQLDLDPQLEA 266
Query: 328 ------PIPLNRIFKKETQ-----ETIDLLYHIMKYDPNIRYSALQCMFNSTYFTDI 373
P P ++ + Q E ID L +++YD R +A + M + YF +
Sbjct: 267 LVGRHVPKPWSKFINADNQHLVSPEAIDFLDKLLQYDHQDRLTAREAM-DHPYFAQV 322
>7291043 [T] KOG0660 Mitogen-activated protein kinase
Length = 392
Score = 124 bits (310), Expect = 3e-28
Identities = 79/292 (27%), Positives = 148/292 (50%), Gaps = 28/292 (9%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQ------DRRFKNRELEIMKLIS-HPNLIDLKY 145
+G G++G+V++ + T V +KKV D + RE+ ++ HPN++ L
Sbjct: 31 MGKGAYGIVWKATDRRTKNTVALKKVFDAFRDETDAQRTYREVIFLRAFRCHPNIVRLVD 90
Query: 146 YFLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVV 205
F ++ + YL + ++M L+ +K L R+ M+QL ++ ++H
Sbjct: 91 IFKASNNLDFYL--VFEFMESDLHNVIKRGNVLKDVHKRF----VMYQLINAIKFIHSG- 143
Query: 206 NVCHRDIKPQNILVDPDTLLLKICDLGSAK---------QLKPNEPNVSYICSRYYRAPE 256
NV HRD+KP NIL+D LK+ D G A+ L+ + Y+ +R+YRAPE
Sbjct: 144 NVIHRDLKPSNILID-SKCRLKVADFGLARTLSSRRIYDDLEQDGMLTDYVATRWYRAPE 202
Query: 257 LIFGATNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNE 316
++ + NYT ID+W GC++ E++ +P+F G S ++Q+ +I+ L T+ +I S+
Sbjct: 203 ILVASRNYTKGIDMWGLGCILGEMIRQKPLFQGTSTVNQIEKIVTSLPNVTKLDIASIGP 262
Query: 317 NYS----EHKFPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSALQCM 364
++ + R L+ + K + I L+ ++ +P+ R +A + +
Sbjct: 263 SFGSVLLSRNIQRDRRYSLDEMMKNCCDDGISLVKALLVLNPHNRLTAKEAI 314
>7289745 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 336
Score = 124 bits (310), Expect = 3e-28
Identities = 91/309 (29%), Positives = 155/309 (49%), Gaps = 36/309 (11%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIK--KVLQDRRFKNRELEIMK-LISHPNLIDLKYYFLE 149
+G G + VF T E V+K K ++ ++ K RE++I++ L N+I L +
Sbjct: 43 LGRGKYSEVFEAINITTTEKCVVKILKPVKKKKIK-REIKILENLRGGTNIITLLAVVKD 101
Query: 150 QSDQELYLNLIVDYMPMSLYQRLK--EFISLHQPMDRYEIKIYMFQLFKSLNYLHQVVNV 207
V P +++ + +F L+Q + YEI+ Y+F+L K+L+Y H + +
Sbjct: 102 P----------VSRTPALIFEHVNNTDFKQLYQTLTDYEIRYYLFELLKALDYCHSM-GI 150
Query: 208 CHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGATNYTTK 267
HRD+KP N+++D + L++ D G A+ P + + SRY++ PEL+ Y
Sbjct: 151 MHRDVKPHNVMIDHENRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYS 210
Query: 268 IDIWSAGCVMAELLL-GQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENYSEHKFPQI 326
+D+WS GC++A ++ +P F G DQLV I KVLGT EE+ + + Y+ P+
Sbjct: 211 LDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGT---EELYAYLDKYNIDLDPRF 267
Query: 327 RPIPLNRIFKKE-------------TQETIDLLYHIMKYDPNIRYSALQCMFNSTYFTDI 373
I L R +K + E +D L +++YD R +A + M + YF I
Sbjct: 268 HDI-LQRHSRKRWERFVHSDNQHLVSPEALDFLDKLLRYDHVDRLTAREAMAH-PYFLPI 325
Query: 374 VSNTGSDSN 382
V+ + +N
Sbjct: 326 VNGQMNPNN 334
>Hs20986514 [T] KOG0660 Mitogen-activated protein kinase
Length = 297
Score = 123 bits (309), Expect = 4e-28
Identities = 78/248 (31%), Positives = 131/248 (52%), Gaps = 21/248 (8%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN--------RELEIMKLISHPNLIDLK 144
VG+G++G V +TG V +KK+ R F++ REL ++K + H N+I L
Sbjct: 30 VGSGAYGSVCAAFDTKTGLRVAVKKL--SRPFQSIIHAKRTYRELRLLKHMKHENVIGLL 87
Query: 145 YYFLEQSDQELY--LNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLH 202
F E + + L+ M L +K Q + ++ ++Q+ + L Y+H
Sbjct: 88 DVFTPARSLEEFNDVYLVTHLMGADLNNIVK-----CQKLTDDHVQFLIYQILRGLKYIH 142
Query: 203 QVVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGAT 262
++ HRD+KP N+ V+ D L KI D G A+ ++ Y+ +R+YRAPE++
Sbjct: 143 SA-DIIHRDLKPSNLAVNEDCEL-KILDFGLARHT--DDEMTGYVATRWYRAPEIMLNWM 198
Query: 263 NYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENYSEHK 322
+Y +DIWS GC+MAELL G+ +FPG IDQL I++++GTP E + ++ + +
Sbjct: 199 HYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKISSESARNY 258
Query: 323 FPQIRPIP 330
+ +P
Sbjct: 259 IQSLTQMP 266
>Hs4506089 [T] KOG0660 Mitogen-activated protein kinase
Length = 557
Score = 123 bits (308), Expect = 6e-28
Identities = 86/299 (28%), Positives = 152/299 (50%), Gaps = 31/299 (10%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKV-LQDRRFKN---RELEIMKLISHPNLIDLKYYFL 148
+G G G+V V +KK+ L D R RE++I++ + H N++ + Y L
Sbjct: 26 LGFGVNGLVLSAVDSRACRKVAVKKIALSDARSMKHALREIKIIRRLDHDNIVKV-YEVL 84
Query: 149 EQSDQELYLNL--------IVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNY 200
+L L + +YM L + L++ + K++M+QL + L Y
Sbjct: 85 GPKGTDLQGELFKFSVAYIVQEYMETDLARLLEQGTLAEE-----HAKLFMYQLLRGLKY 139
Query: 201 LHQVVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYIC----SRYYRAPE 256
+H NV HRD+KP NI + + L+LKI D G A+ + + + Y+ +++YR+P
Sbjct: 140 IHSA-NVLHRDLKPANIFISTEDLVLKIGDFGLARIVDQHYSHKGYLSEGLVTKWYRSPR 198
Query: 257 LIFGATNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQ---LVEIIKVLGTPTREEICS 313
L+ NYT ID+W+AGC++AE+L G+ +F G +++Q ++E I V+ ++E+
Sbjct: 199 LLLSPNNYTKAIDMWAAGCILAEMLTGRMLFAGAHELEQMQLILETIPVIREEDKDELLR 258
Query: 314 MNENYSEHKFPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSA---LQCMFNSTY 369
+ ++ + R PL ++ + E ID L I+ ++P R +A LQ + S Y
Sbjct: 259 VMPSFVSSTWEVKR--PLRKLLPEVNSEAIDFLEKILTFNPMDRLTAEMGLQHPYMSPY 315
>YPR054w [T] KOG0660 Mitogen-activated protein kinase
Length = 388
Score = 122 bits (307), Expect = 8e-28
Identities = 83/303 (27%), Positives = 147/303 (48%), Gaps = 41/303 (13%)
Query: 91 EIVGNGSFGVVFRTKVKETG---------------EDVVIKKVLQDRRFKNRELEIMKLI 135
+ +G G++G V K K +++++K+ +++ +F N ++
Sbjct: 42 QFLGKGAYGTVCSVKFKGRSPAARIAVKKISNIFNKEILLKRAIRELKFMNFFKGHKNIV 101
Query: 136 SHPNLIDLKYYFLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLF 195
NLIDL+ D ++DY L + I + + IK +++Q+
Sbjct: 102 ---NLIDLEIVTSSPYDGLYCYQELIDY-------DLAKVIHSSVQLSEFHIKYFLYQIL 151
Query: 196 KSLNYLHQVVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPN--------EPNVS-Y 246
L Y+H +V HRD+KP NIL + L KICD G A+ + +P+++ Y
Sbjct: 152 CGLKYIHSA-DVIHRDLKPGNILCTLNGCL-KICDFGLARGIHAGFFKCHSTVQPHITNY 209
Query: 247 ICSRYYRAPELIFGATNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTP 306
+ +R+YRAPEL+ Y+ +DIW+ GC++AE +P+F G + Q+ EIIKVLGTP
Sbjct: 210 VATRWYRAPELLLSNQPYSKSVDIWAVGCILAEFYARKPVFMGRDSMHQIFEIIKVLGTP 269
Query: 307 TREEICSMNE----NYSEH-KFPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSAL 361
++ + N ++ P + IP + IF + E I+L+ ++ +D R +
Sbjct: 270 DKDILIKFGTIKAWNLGKNSNNPVYKKIPWSNIFPFASHEAINLIESLLHWDSTHRLNVE 329
Query: 362 QCM 364
Q +
Sbjct: 330 QAI 332
>Hs14110390 [D] KOG0600 Cdc2-related protein kinase
Length = 1452
Score = 122 bits (307), Expect = 8e-28
Identities = 87/299 (29%), Positives = 153/299 (51%), Gaps = 36/299 (12%)
Query: 92 IVGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN------RELEIMKLISHPNLIDLKY 145
I+G G++G V++ + K+TGE V +KKV D + RE++I++ ++H ++I++K
Sbjct: 710 IIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTHQSIINMKE 769
Query: 146 YFLEQSDQELYLN------LIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLN 199
++ D + L+ +YM L L+ + +H + IK +M QL + L+
Sbjct: 770 IVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGL-VH--FNENHIKSFMRQLMEGLD 826
Query: 200 YLHQVVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNE--PNVSYICSRYYRAPEL 257
Y H+ N HRDIK NIL++ + +K+ D G A+ E P + + + +YR PEL
Sbjct: 827 YCHKK-NFLHRDIKCSNILLN-NRGQIKLADFGLARLYSSEESRPYTNKVITLWYRPPEL 884
Query: 258 IFGATNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNEN 317
+ G YT ID+WS GC++ EL +PIF ++ QL I ++ G+P +
Sbjct: 885 LLGEERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELISRICGSPCPAVWPDV--- 941
Query: 318 YSEHKFPQIRPIPLNRIFKKETQE--------TIDLLYHIMKYDPNIRYS---ALQCMF 365
K P + + ++++ +E +DL +++ DP+ R + ALQC F
Sbjct: 942 ---IKLPYFNTMKPKKQYRRKLREEFVFIPAAALDLFDYMLALDPSKRCTAEQALQCEF 997
>Hs14110387 [D] KOG0600 Cdc2-related protein kinase
Length = 1512
Score = 122 bits (307), Expect = 8e-28
Identities = 87/299 (29%), Positives = 153/299 (51%), Gaps = 36/299 (12%)
Query: 92 IVGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN------RELEIMKLISHPNLIDLKY 145
I+G G++G V++ + K+TGE V +KKV D + RE++I++ ++H ++I++K
Sbjct: 710 IIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTHQSIINMKE 769
Query: 146 YFLEQSDQELYLN------LIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLN 199
++ D + L+ +YM L L+ + +H + IK +M QL + L+
Sbjct: 770 IVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGL-VH--FNENHIKSFMRQLMEGLD 826
Query: 200 YLHQVVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNE--PNVSYICSRYYRAPEL 257
Y H+ N HRDIK NIL++ + +K+ D G A+ E P + + + +YR PEL
Sbjct: 827 YCHKK-NFLHRDIKCSNILLN-NRGQIKLADFGLARLYSSEESRPYTNKVITLWYRPPEL 884
Query: 258 IFGATNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNEN 317
+ G YT ID+WS GC++ EL +PIF ++ QL I ++ G+P +
Sbjct: 885 LLGEERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELISRICGSPCPAVWPDV--- 941
Query: 318 YSEHKFPQIRPIPLNRIFKKETQE--------TIDLLYHIMKYDPNIRYS---ALQCMF 365
K P + + ++++ +E +DL +++ DP+ R + ALQC F
Sbjct: 942 ---IKLPYFNTMKPKKQYRRKLREEFVFIPAAALDLFDYMLALDPSKRCTAEQALQCEF 997
>ECU08g0230 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 265
Score = 122 bits (307), Expect = 8e-28
Identities = 78/220 (35%), Positives = 128/220 (57%), Gaps = 19/220 (8%)
Query: 92 IVGNGSFGVVFRTKVKETGEDVVIKKVLQDRR-----FKNRELEIMKLISHPNLIDLKYY 146
++G+G++G V+ ET E V +K++ + + RE+ I+K +SH N+I L
Sbjct: 9 LIGSGTYGEVYEAIDTETKEKVALKRIRLNEKEGMPGTALREISILKKLSHRNIISLVSI 68
Query: 147 FLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVVN 206
+ L+ P Y+ LK++I ++ + E+ + QL ++YLH++ N
Sbjct: 69 IHTDA-------LLTMVFPFIDYE-LKKYIGMNTGKNIMEL---VNQLICGVHYLHRM-N 116
Query: 207 VCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSY-ICSRYYRAPELIFGATNYT 265
V HRD+KPQNILV D +L KI D G ++ L+ P S + + +YR+PEL+ G+T+Y
Sbjct: 117 VVHRDLKPQNILVTSDGVL-KIADFGLSRSLEIRVPPYSSEVVTLWYRSPELLMGSTSYR 175
Query: 266 TKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGT 305
+DIWS GC++ E++ +P+FPGESK +QL I + GT
Sbjct: 176 FYVDIWSLGCIIYEMITLEPLFPGESKENQLTLIRRKAGT 215
>Hs20986516 [T] KOG0660 Mitogen-activated protein kinase
Length = 307
Score = 122 bits (306), Expect = 1e-27
Identities = 77/227 (33%), Positives = 123/227 (53%), Gaps = 21/227 (9%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN--------RELEIMKLISHPNLIDLK 144
VG+G++G V +TG V +KK+ R F++ REL ++K + H N+I L
Sbjct: 30 VGSGAYGSVCAAFDTKTGLRVAVKKL--SRPFQSIIHAKRTYRELRLLKHMKHENVIGLL 87
Query: 145 YYFLEQSDQELY--LNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLH 202
F E + + L+ M L +K Q + ++ ++Q+ + L Y+H
Sbjct: 88 DVFTPARSLEEFNDVYLVTHLMGADLNNIVK-----CQKLTDDHVQFLIYQILRGLKYIH 142
Query: 203 QVVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGAT 262
++ HRD+KP N+ V+ D L KI D G A+ ++ Y+ +R+YRAPE++
Sbjct: 143 SA-DIIHRDLKPSNLAVNEDCEL-KILDFGLARHT--DDEMTGYVATRWYRAPEIMLNWM 198
Query: 263 NYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTRE 309
+Y +DIWS GC+MAELL G+ +FPG IDQL I++++GTP E
Sbjct: 199 HYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAE 245
>CE29466 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 390
Score = 122 bits (306), Expect = 1e-27
Identities = 93/316 (29%), Positives = 152/316 (47%), Gaps = 37/316 (11%)
Query: 96 GSFGVVFRTKVKETGEDVVIKKVLQ------DRRFKNRELEIMKLISHPNLIDLKYYFLE 149
G+ G V T + V IKK+ Q + RE ++ I HPN+I L F
Sbjct: 47 GAQGTVVMADDLVTTQRVAIKKMQQPFVMTMSAKRAYREFILLTTIKHPNIIRLLNAFTP 106
Query: 150 QSDQELY--LNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVVNV 207
+ + + L+++ M +L++ + +D + +++Q ++ +LH V
Sbjct: 107 DTSLSTFREVYLVMELMTHNLHEVIHRL-----RLDHKTLSFFVYQSLCAIKHLHNS-GV 160
Query: 208 CHRDIKPQNILVDPDTLLLKICDLGSA--KQLKPNEPNVSYICSRYYRAPELIFGATNYT 265
HRD+KP NI+V+ D +LK+ D G A K + + Y+ +RYYRAPE+I G Y+
Sbjct: 161 IHRDLKPSNIVVN-DRCVLKVLDFGLARKKNVDTSMRMSDYVVTRYYRAPEVILGLP-YS 218
Query: 266 TKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENYS------ 319
K+DIWS GC+ AE++ +FPG+ +IDQ +I VLGTP I + ++ +
Sbjct: 219 EKVDIWSVGCIFAEMINHTVLFPGKDRIDQWTKIYSVLGTPDDHFISQLGQSAAMYVRSL 278
Query: 320 -EHKFPQIRPIPLNRIFKKETQE---------TIDLLYHIMKYDPNIRYS---ALQCMFN 366
H+ I + F ET+ DLL++++K +P RYS AL +
Sbjct: 279 PRHQARAFSEIVPDTNFLPETENPRVHLTPHVARDLLFNMLKINPEERYSVEDALNHPYV 338
Query: 367 STYFTDIVSNTGSDSN 382
+F D N + N
Sbjct: 339 KLWFKDDEVNAPASEN 354
>CE17062 [T] KOG0660 Mitogen-activated protein kinase
Length = 448
Score = 122 bits (306), Expect = 1e-27
Identities = 92/324 (28%), Positives = 160/324 (48%), Gaps = 66/324 (20%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN--------RELEIMKLISHPNLIDLK 144
+G G++GVV + + TG+ V IKK R F++ REL++++ + H N++++
Sbjct: 55 LGEGAYGVVCTAEYEPTGDRVAIKKFF--RPFQSTIHAKRTYRELKLLRTLQHDNVLEMI 112
Query: 145 YYFLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYL-HQ 203
F D N V ++ + + L+ + + + D +I++ ++Q+ + L Y+ HQ
Sbjct: 113 DVFTPDPDASSLNN--VYFVSVLMGSDLQNIMKIQRLTDE-QIQLLIYQVLRGLKYMSHQ 169
Query: 204 VVN---------------------------VCHRDIKPQNILVDP-------------DT 223
N + HRD+KP NI V+
Sbjct: 170 NFNSTIILKKLMHPFQRRNTRFRLYIHSAGIIHRDLKPSNIAVNERCEVKVFLSFSQLSF 229
Query: 224 LLL---KICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGATNYTTKIDIWSAGCVMAEL 280
L+L KI D G A+ + Y+ +R+YRAPE++ +YT +D+WS GC++AEL
Sbjct: 230 LILSFFKILDFGLARA--QDAEMTGYVATRWYRAPEIMLNWMHYTQTVDVWSVGCILAEL 287
Query: 281 LLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNE-----NYSEHKFPQIRPIPLNRIF 335
+ G+P+FPG+ IDQL +I+ V+GTP +EE S + NY +++ P IR +F
Sbjct: 288 VSGRPLFPGDDHIDQLTKIMSVVGTP-KEEFWSKIQSEEARNYIKNRSPIIRQ-DFVTLF 345
Query: 336 KKETQETIDLLYHIMKYDPNIRYS 359
+ ++LL ++ DP+ R S
Sbjct: 346 PMASPYALELLEMMLILDPDRRIS 369
>7292375 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 509
Score = 122 bits (306), Expect = 1e-27
Identities = 78/256 (30%), Positives = 132/256 (51%), Gaps = 18/256 (7%)
Query: 91 EIVGNGSFGVVFRTKVKETGEDVVIKKV-LQDRRFKN----RELEIMKLISHPNLIDLKY 145
E +G GS+ V++ K T + V +K++ LQ+ RE ++K + H N++ L
Sbjct: 196 EPLGEGSYATVYKGFSKLTYQRVALKEIRLQEEEGAPFTAIREASLLKELKHSNIVTLHD 255
Query: 146 YFLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVV 205
+ L + +Y+ L Q +++ +D +++++FQL + L+Y H+
Sbjct: 256 IVHTRET----LTFVFEYVNTDLSQYMEKHPG---GLDHRNVRLFLFQLLRGLSYCHKR- 307
Query: 206 NVCHRDIKPQNILVDPDTLLLKICDLGSAKQLK-PNEPNVSYICSRYYRAPELIFGATNY 264
V HRD+KPQN+L+ D LK+ D G A+ P+ + + +YR P+++ G+T Y
Sbjct: 308 RVLHRDVKPQNLLIS-DCGELKLADFGLARAKSVPSHTYSHEVVTLWYRPPDVLLGSTEY 366
Query: 265 TTKIDIWSAGCVMAELLLGQPIFPG-ESKIDQLVEIIKVLGTPTREEICSMNE--NYSEH 321
+T +D+W GC+ E++ G P FPG DQL +I K+LGTPT + + Y H
Sbjct: 367 STSLDMWGVGCIFVEMVTGMPTFPGIRDTYDQLDKIFKLLGTPTEDTWPGVTHFPGYKPH 426
Query: 322 KFPQIRPIPLNRIFKK 337
K RP L F +
Sbjct: 427 KLGFYRPRKLGHNFPR 442
>Hs20986521 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 427
Score = 122 bits (305), Expect = 1e-27
Identities = 77/227 (33%), Positives = 120/227 (51%), Gaps = 21/227 (9%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN--------RELEIMKLISHPNLIDLK 144
+G+G+ G+V +V IKK+ R F+N REL +MK ++H N+I L
Sbjct: 32 IGSGAQGIVCAAYDAILERNVAIKKL--SRPFQNQTHAKRAYRELVLMKCVNHKNIIGLL 89
Query: 145 YYFLEQSDQELYLN--LIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLH 202
F Q E + + ++++ M +L Q ++ +D + ++Q+ + +LH
Sbjct: 90 NVFTPQKSLEEFQDVYIVMELMDANLCQVIQ------MELDHERMSYLLYQMLCGIKHLH 143
Query: 203 QVVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGAT 262
+ HRD+KP NI+V D L KI D G A+ + Y+ +RYYRAPE+I G
Sbjct: 144 SA-GIIHRDLKPSNIVVKSDCTL-KILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGM- 200
Query: 263 NYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTRE 309
Y +DIWS GC+M E++ G +FPG IDQ ++I+ LGTP E
Sbjct: 201 GYKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQLGTPCPE 247
>Hs20986519 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 384
Score = 122 bits (305), Expect = 1e-27
Identities = 77/227 (33%), Positives = 120/227 (51%), Gaps = 21/227 (9%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN--------RELEIMKLISHPNLIDLK 144
+G+G+ G+V +V IKK+ R F+N REL +MK ++H N+I L
Sbjct: 32 IGSGAQGIVCAAYDAILERNVAIKKL--SRPFQNQTHAKRAYRELVLMKCVNHKNIIGLL 89
Query: 145 YYFLEQSDQELYLN--LIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLH 202
F Q E + + ++++ M +L Q ++ +D + ++Q+ + +LH
Sbjct: 90 NVFTPQKSLEEFQDVYIVMELMDANLCQVIQ------MELDHERMSYLLYQMLCGIKHLH 143
Query: 203 QVVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGAT 262
+ HRD+KP NI+V D L KI D G A+ + Y+ +RYYRAPE+I G
Sbjct: 144 SA-GIIHRDLKPSNIVVKSDCTL-KILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGM- 200
Query: 263 NYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTRE 309
Y +DIWS GC+M E++ G +FPG IDQ ++I+ LGTP E
Sbjct: 201 GYKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQLGTPCPE 247
>Hs7706549 [D] KOG0600 Cdc2-related protein kinase
Length = 1490
Score = 121 bits (304), Expect = 2e-27
Identities = 88/304 (28%), Positives = 154/304 (49%), Gaps = 34/304 (11%)
Query: 92 IVGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN------RELEIMKLISHPNLIDLKY 145
I+G G++G V++ + K+TGE V +KKV D + RE++I++ + H +++++K
Sbjct: 732 IIGEGTYGQVYKARDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLIHRSVVNMKE 791
Query: 146 YFLEQSDQELYLN------LIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLN 199
++ D + L+ +YM L L+ + +H D IK +M QL + L
Sbjct: 792 IVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGL-VHFSEDH--IKSFMKQLMEGLE 848
Query: 200 YLHQVVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNE--PNVSYICSRYYRAPEL 257
Y H+ N HRDIK NIL++ ++ +K+ D G A+ E P + + + +YR PEL
Sbjct: 849 YCHKK-NFLHRDIKCSNILLN-NSGQIKLADFGLARLYNSEESRPYTNKVITLWYRPPEL 906
Query: 258 IFGATNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNEN 317
+ G YT ID+WS GC++ EL +PIF ++ QL I ++ G+P +
Sbjct: 907 LLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDV--- 963
Query: 318 YSEHKFPQIRPIPLNRIFKKETQE--------TIDLLYHIMKYDPNIRYSALQCMFNSTY 369
K P + + +++ +E +DLL H++ DP+ R +A Q + S +
Sbjct: 964 ---IKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTL-QSDF 1019
Query: 370 FTDI 373
D+
Sbjct: 1020 LKDV 1023
>CE29318 [T] KOG0660 Mitogen-activated protein kinase
Length = 474
Score = 121 bits (304), Expect = 2e-27
Identities = 100/365 (27%), Positives = 184/365 (50%), Gaps = 47/365 (12%)
Query: 30 ETEMDSILPSDDLKQGSLHSKNSHGNDVKIVPDEDEVITRRTVVKGHSNPEESVVI---- 85
E E L ++++K+ S+ + GN+ + +E++++++ H + V+I
Sbjct: 53 EQEQQKKLAAENIKKQSIEAT---GNNEMVGEEEEDILSKPC--GPHKRRFQFVMIRNIT 107
Query: 86 ---------SCGTPEIVGNGSFGVVFRTK-VKETG--EDVVIKKVLQD------RRFKNR 127
+ E +G GSFG V +T V G V IKK+ + R R
Sbjct: 108 FAIPEGYDVEPNSIEYLGGGSFGNVIKTSAVCRDGLRRYVAIKKMREPFFDPHHARRIFR 167
Query: 128 ELEIMKLISHPNLI-DLKYYFLEQSDQELYLNLIVDYMPMSLYQRLKEFISL-HQPMDRY 185
E ++++L+ H N+I L Y ++ + + ++ ++ SLYQ LK+ + +
Sbjct: 168 ETKLLQLMRHDNIICALDIYTPDEENDFRDVYVVTEFAGRSLYQILKQQRDYGRRVLTDE 227
Query: 186 EIKIYMFQLFKSLNYLHQVVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVS 245
IK ++Q+ ++L Y+H N+ HRD+KP N+ + D+ L+ I D G A+ L+ + +++
Sbjct: 228 HIKFIIYQIIRALKYIHSA-NIIHRDLKPGNLALTDDSDLM-ILDFGLARSLEKKDTSLT 285
Query: 246 -YICSRYYRAPELIFGATN-YTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVL 303
Y+ +R+YR+PE+I+ + YT D+WS GC+ AELL G+P+FPG+ Q I ++
Sbjct: 286 QYVQTRWYRSPEVIYWKIDSYTNLADMWSLGCIAAELLTGEPLFPGDEPNAQYQRITQLC 345
Query: 304 GTPTRE-----------EICSMNENYSEHKFPQIRPIPLNRIFKKETQETIDLLYHIMKY 352
G+P E I ++ ++Y+ HK R + +++ IDLL ++
Sbjct: 346 GSPDEELLTKIENDNSSAIKAVIQSYTTHKRRNFRDV---FSAHNPSEDFIDLLEKLLVL 402
Query: 353 DPNIR 357
DP R
Sbjct: 403 DPEKR 407
>CE17305 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 375
Score = 121 bits (304), Expect = 2e-27
Identities = 98/346 (28%), Positives = 168/346 (48%), Gaps = 43/346 (12%)
Query: 96 GSFGVVFRTKVKETGEDVVIKKVLQ------DRRFKNRELEIMKLISHPNLIDLKYYFLE 149
G+ G+V T + V IKK+ Q R RE ++ + HPN+I L F
Sbjct: 38 GAQGIVVMADDLVTTQRVAIKKMQQPFLLTMSARRAYREFILLTTLKHPNIIRLLNAFTP 97
Query: 150 QSD----QELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVV 205
+ QE+YL ++++M +L++ + +D + ++Q ++ +LH +
Sbjct: 98 DTSLSSFQEVYL--VMEFMTHNLHEVIHRL-----RLDHETLSFLVYQSLCAIKHLHNL- 149
Query: 206 NVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGATNYT 265
HRD+KP NI+V+ + +LK+ D G A++ + Y+ +RYYRAPE+I G NY+
Sbjct: 150 GFIHRDLKPSNIVVN-ERCVLKVLDFGLARRRNVDMRMSDYVGTRYYRAPEVILGL-NYS 207
Query: 266 TKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMN-------ENY 318
K+DIWS GC++AE++ +FPG+ DQ +I VL TP I + +
Sbjct: 208 EKVDIWSVGCILAEMINHTVLFPGKDIRDQWTQISSVLRTPDDHFINQLEPIGAVYVRSL 267
Query: 319 SEHKFPQIRPIPLNRIFKKETQE---------TIDLLYHIMKYDPNIRYSALQCMFNSTY 369
+H I + F ET+ DLL++++K +P RYS + +
Sbjct: 268 PQHLARAFNEIVPDSNFLPETENPKDHLTLHMARDLLFNMLKINPEERYSVEDALNHPYT 327
Query: 370 FTDIVSNTGS---DSNLSLIDSLPLLHFEE---SELQGL-SSNDIY 408
D V+ S D ++ ID L+ ++ +E+QG + +DI+
Sbjct: 328 MDDEVNAPASEIPDDEVNDIDDWTLIEWKRLIFNEVQGYQTDHDIF 373
>Hs7106269 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 452
Score = 121 bits (303), Expect = 2e-27
Identities = 82/288 (28%), Positives = 142/288 (48%), Gaps = 37/288 (12%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQDRR---FKNRELEIMKLISHPN----LIDLKY 145
+G G+ G+VF+ K ETGE + +KKV R F N+ L +K + ++ LK
Sbjct: 10 IGEGAHGIVFKAKHVETGEIIALKKVALRRLEDGFPNQALREIKALQEMEDNQYVVQLKA 69
Query: 146 YFLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVV 205
F L ++M L + ++ +P+ + ++K Y+ L K + + H
Sbjct: 70 VFPHGGG----FVLAFEFMLSDLAEVVRH---AQRPLAQAQVKSYLQMLLKGVAFCH-AN 121
Query: 206 NVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGATNYT 265
N+ HRD+KP N+L+ L KI D G A+ P+ G+ YT
Sbjct: 122 NIVHRDLKPANLLISASGQL-KIADFGLARVFSPD-------------------GSRLYT 161
Query: 266 TKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNE--NYSEHKF 323
++ S GC+M ELL G P+FPG++ I+QL ++++LGTP + + E +Y++ F
Sbjct: 162 HQVATRSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYNKISF 221
Query: 324 PQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSALQCMFNSTYFT 371
+ P+PL + + + +DLL + Y P+ R +A + + + +FT
Sbjct: 222 KEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQYFFT 269
>At1g57700 [D] KOG0600 Cdc2-related protein kinase
Length = 686
Score = 120 bits (302), Expect = 3e-27
Identities = 90/294 (30%), Positives = 148/294 (49%), Gaps = 33/294 (11%)
Query: 91 EIVGNGSFGVVFRTKVKETGEDVVIKKVL------QDRRFKNRELEIMKLISHPNLIDLK 144
E++G G++ V+R + ET + V +KKV + RF RE+ I++ ++HPN++ L+
Sbjct: 150 EMIGQGTYSSVYRARDLETNQIVALKKVRFANMDPESVRFMAREIIILRRLNHPNVMKLE 209
Query: 145 YYFLEQSDQELYLNLIVDYMPMSLYQRLKE-FISLHQPMDRYEIKIYMFQLFKSLNYLHQ 203
+ ++ +YL I +YM L I Q QL L + H
Sbjct: 210 GLIISKASGSMYL--IFEYMDHDLAGLASTPGIKFSQAQ----------QLLLGLEHCHS 257
Query: 204 VVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPN--EPNVSYICSRYYRAPELIFGA 261
V HRDIK N+L+D + L KI D G + + +P S + + +YR PEL+ G+
Sbjct: 258 C-GVLHRDIKCSNLLLDRNNNL-KIGDFGLSNFYRGQRKQPLTSRVVTLWYRPPELLLGS 315
Query: 262 TNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENYSEH 321
T+Y +D+WS GC++AEL G+P+ PG ++++Q+ +I K+ G+P+ E ++
Sbjct: 316 TDYGVTVDLWSTGCILAELFTGKPLLPGRTEVEQMHKIFKLCGSPSEEYWRRSRLRHATI 375
Query: 322 KFPQIRPIPLNR----IFKKETQETIDLLYHIMKYDPNIR---YSALQCMFNST 368
PQ P R FK + LL ++ +P+ R SALQ F +T
Sbjct: 376 FKPQ---HPYKRCVADTFKDLPSSALALLEVLLAVEPDARGTASSALQSEFFTT 426
>YKL139w [D] KOG0600 Cdc2-related protein kinase
Length = 528
Score = 120 bits (301), Expect = 4e-27
Identities = 89/295 (30%), Positives = 148/295 (50%), Gaps = 27/295 (9%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKV-LQDRR-----FKNRELEIMKLISHPNLIDLKYY 146
VG G++G V++ K T + V +KK+ LQ R RE+++++ HPN+ +K
Sbjct: 189 VGEGTYGKVYKAKNTNTEKLVALKKLRLQGEREGFPITSIREIKLLQSFDHPNVSTIKEI 248
Query: 147 FLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVVN 206
+E S + +Y+ I +Y L L ++ + + K QL + YLH
Sbjct: 249 MVE-SQKTVYM--IFEYADNDLSGLL---LNKEVQISHSQCKHLFKQLLLGMEYLHDN-K 301
Query: 207 VCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGATNYTT 266
+ HRD+K NIL+D L KI D G A+++ + + + +YR PEL+ G TNY T
Sbjct: 302 ILHRDVKGSNILIDNQGNL-KITDFGLARKMNSRADYTNRVITLWYRPPELLLGTTNYGT 360
Query: 267 KIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENYSEHKFPQI 326
++D+W GC++ EL IF G ++++Q+ I K++GTPT I S Y F I
Sbjct: 361 EVDMWGCGCLLVELFNKTAIFQGSNELEQIESIFKIMGTPT---INSWPTLYDMPWFFMI 417
Query: 327 RPIP----LNRIFKK-----ETQETIDLLYHIMKYDPNIRYSALQCMFNSTYFTD 372
P +N +K + + + L +++ YD R+SA + + S YF +
Sbjct: 418 MPQQTTKYVNNFSEKFKSVLPSSKCLQLAINLLCYDQTKRFSATEAL-QSDYFKE 471
>Hs20986499 [T] KOG0660 Mitogen-activated protein kinase
Length = 677
Score = 120 bits (301), Expect = 4e-27
Identities = 66/197 (33%), Positives = 109/197 (54%), Gaps = 10/197 (5%)
Query: 172 LKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVVNVCHRDIKPQNILVDPDTLLLKICDL 231
L + I QP+ ++ +++QL + L Y+H V HRD+KP N+LV+ + LKI D
Sbjct: 5 LHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSA-QVIHRDLKPSNLLVN-ENCELKIGDF 62
Query: 232 GSAKQL--KPNEPN---VSYICSRYYRAPELIFGATNYTTKIDIWSAGCVMAELLLGQPI 286
G A+ L P E Y+ +R+YRAPEL+ YT ID+WS GC+ E+L + +
Sbjct: 63 GMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARRQL 122
Query: 287 FPGESKIDQLVEIIKVLGTPTREEICSMNENYSE---HKFPQIRPIPLNRIFKKETQETI 343
FPG++ + QL I+ VLGTP+ I ++ P +P+P ++ ++ +
Sbjct: 123 FPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQAL 182
Query: 344 DLLYHIMKYDPNIRYSA 360
LL +++++P+ R SA
Sbjct: 183 SLLGRMLRFEPSARISA 199
>CE29073 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 700
Score = 120 bits (301), Expect = 4e-27
Identities = 77/280 (27%), Positives = 149/280 (52%), Gaps = 17/280 (6%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQDRR-----FKNRELEIMKLISHPNLIDLKYYF 147
+G G++ VFR + T + V +K++ ++ RE+ +++ + H N++ L +
Sbjct: 367 LGEGTYATVFRGRSILTNKFVALKEIRLEQEEGAPCTAIREVSLLRNLRHANVVTL--HD 424
Query: 148 LEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVVNV 207
+ +D+ L L+ +Y+ L Q + S + M I+++++QL + L Y HQ V
Sbjct: 425 IIHTDR--LLTLVFEYVDRDLKQYMD---SCNNAMQMNNIRLFLYQLLRGLAYCHQR-RV 478
Query: 208 CHRDIKPQNILVDPDTLLLKICDLGSAKQLK-PNEPNVSYICSRYYRAPELIFGATNYTT 266
HRD+KPQN+L+ L K+ D G A+ P + + + + +YR P+++ G+T+Y+T
Sbjct: 479 LHRDLKPQNLLITAKGEL-KLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTDYST 537
Query: 267 KIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENYSEHKFP-- 324
ID+W GC++ E++ G+ +FPG + +QL I + LG+P + ++ E + + +
Sbjct: 538 HIDMWGVGCILFEMIAGRALFPGGTPTEQLGLIFRTLGSPRPDRHPTICEKPTFYPYANR 597
Query: 325 QIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSALQCM 364
P PL R + +LL ++Y+ R SA + +
Sbjct: 598 HYNPDPLCRQIPRIDAHGFELLMKFLQYEGKDRVSAAEAV 637
>CE06779 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 577
Score = 120 bits (301), Expect = 4e-27
Identities = 77/280 (27%), Positives = 149/280 (52%), Gaps = 17/280 (6%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQDRR-----FKNRELEIMKLISHPNLIDLKYYF 147
+G G++ VFR + T + V +K++ ++ RE+ +++ + H N++ L +
Sbjct: 244 LGEGTYATVFRGRSILTNKFVALKEIRLEQEEGAPCTAIREVSLLRNLRHANVVTL--HD 301
Query: 148 LEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVVNV 207
+ +D+ L L+ +Y+ L Q + S + M I+++++QL + L Y HQ V
Sbjct: 302 IIHTDR--LLTLVFEYVDRDLKQYMD---SCNNAMQMNNIRLFLYQLLRGLAYCHQR-RV 355
Query: 208 CHRDIKPQNILVDPDTLLLKICDLGSAKQLK-PNEPNVSYICSRYYRAPELIFGATNYTT 266
HRD+KPQN+L+ L K+ D G A+ P + + + + +YR P+++ G+T+Y+T
Sbjct: 356 LHRDLKPQNLLITAKGEL-KLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTDYST 414
Query: 267 KIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENYSEHKFP-- 324
ID+W GC++ E++ G+ +FPG + +QL I + LG+P + ++ E + + +
Sbjct: 415 HIDMWGVGCILFEMIAGRALFPGGTPTEQLGLIFRTLGSPRPDRHPTICEKPTFYPYANR 474
Query: 325 QIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSALQCM 364
P PL R + +LL ++Y+ R SA + +
Sbjct: 475 HYNPDPLCRQIPRIDAHGFELLMKFLQYEGKDRVSAAEAV 514
>At5g67380 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 333
Score = 120 bits (301), Expect = 4e-27
Identities = 84/296 (28%), Positives = 151/296 (50%), Gaps = 28/296 (9%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFK-NRELEIMK-LISHPNLIDLKYYFLEQ 150
VG G + VF + E +IK + ++ K RE++I++ L PN++ L +Q
Sbjct: 40 VGRGKYSEVFEGINVNSKEKCIIKILKPVKKKKIRREIKILQNLCGGPNIVKLLDVVRDQ 99
Query: 151 SDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVVNVCHR 210
+ +LI +Y+ + +F L+ + Y+I+ Y+++L K+L++ H + HR
Sbjct: 100 HSKTP--SLIFEYVNST------DFKVLYPTLTDYDIRYYIYELLKALDFCHSQ-GIMHR 150
Query: 211 DIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGATNYTTKIDI 270
D+KP N+++D + L++ D G A+ P + + SRY++ PEL+ +Y +D+
Sbjct: 151 DVKPHNVMIDHELRKLRLIDWGLAEFYHPGKEYNVRVASRYFKGPELLVDLQDYDYSLDM 210
Query: 271 WSAGCVMAELLL-GQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENYSEHKFPQIRPI 329
WS GC+ A ++ +P F G DQLV+I KVLGT +E+ + Y PQ+ +
Sbjct: 211 WSLGCMFAGMIFRKEPFFYGHDNQDQLVKIAKVLGT---DELNAYLNKYQLELDPQLEAL 267
Query: 330 -------PLNRIFKKETQ-----ETIDLLYHIMKYDPNIRYSALQCMFNSTYFTDI 373
P ++ + Q E ID L +++YD R +A + M ++ YF +
Sbjct: 268 VGRHSRKPWSKFINADNQHLVSPEAIDFLDKLLRYDHQDRLTAKEAMAHA-YFAQV 322
>CE27220 [T] KOG0660 Mitogen-activated protein kinase
Length = 472
Score = 119 bits (298), Expect = 8e-27
Identities = 71/235 (30%), Positives = 124/235 (52%), Gaps = 21/235 (8%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQDR------RFKNRELEIMKLISHPNLIDLKYY 146
+G+G+FG+V + + V IKKV R RE+ +++ I+HPN++ L+
Sbjct: 88 IGSGAFGIVCEAVETSSNQKVAIKKVAHASATPTLARRTLREIRVLRYINHPNIVPLRDI 147
Query: 147 FLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVVN 206
F + + + L++D M +L+ + P++ + I ++ QL + L YLH
Sbjct: 148 FRTKGPLGIDVFLVMDLMQNNLHHII---YGNEDPLEEHYINAFLGQLLRGLEYLHAAC- 203
Query: 207 VCHRDIKPQNILVDPDTLLLKICDLGSAK-----QLKPNEPNVSYICSRY-----YRAPE 256
+ HRD+KP N+LV+ D L +I D G AK K ++ Y +++ YRAPE
Sbjct: 204 IAHRDLKPSNLLVNQDGTL-RIADFGMAKCADNSSKKHDDEEHCYYMTQHVATLPYRAPE 262
Query: 257 LIFGATNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEI 311
L+F ++T +D+W+ GC+ E+++ I PG S Q+ ++ +LG P +E I
Sbjct: 263 LLFVLPEHSTAVDMWAVGCIFGEMVIRNEILPGRSVQGQIKMLLTMLGQPPQEVI 317
>At2g23070 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 432
Score = 119 bits (298), Expect = 8e-27
Identities = 81/296 (27%), Positives = 147/296 (49%), Gaps = 33/296 (11%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIK--KVLQDRRFKNRELEIMK-LISHPNLIDLKYYFLE 149
VG G + VF E VIK K ++ ++ K RE++I++ L PN++ L +
Sbjct: 138 VGRGKYSEVFEGIHATDNEKCVIKILKPVKKKKIK-REIKILQNLCGGPNIVKLLDIVRD 196
Query: 150 QSDQELYLNLIVDYMPMSLYQRL--KEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVVNV 207
Q + P +++ + K+F L+ + Y+++ Y+F+L K+L++ H +
Sbjct: 197 QQSKT----------PSLIFEHVNNKDFKVLYPTLSDYDVRYYIFELLKALDFCHSR-GI 245
Query: 208 CHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGATNYTTK 267
HRD+KP N+++D + L++ D G A+ P + + SRY++ PEL+ +Y
Sbjct: 246 MHRDVKPHNVMIDHEQRKLRLIDWGLAEFYHPGKEYNVRVASRYFKGPELLVDLQDYDYS 305
Query: 268 IDIWSAGCVMAELLL-GQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENYSEHKFPQI 326
+D+WS GC+ A ++ +P F G DQLV+I KVLGT +E+ + Y P +
Sbjct: 306 LDLWSLGCMFAGMIFRKEPFFYGHDNYDQLVKIAKVLGT---DELNAYLNKYRIELDPNL 362
Query: 327 RPI-------PLNRIFKKETQ-----ETIDLLYHIMKYDPNIRYSALQCMFNSTYF 370
+ P + E Q E +D + +++YD R +A + M + ++
Sbjct: 363 TSLVGRHSRKPWTKFINSENQHLAVPEAVDFVDKLLRYDHQERPTAKEAMAHPYFY 418
>Hs4506095 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 384
Score = 119 bits (297), Expect = 1e-26
Identities = 75/227 (33%), Positives = 120/227 (52%), Gaps = 21/227 (9%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN--------RELEIMKLISHPNLIDLK 144
+G+G+ G+V +V IKK+ R F+N REL +MK ++H N+I L
Sbjct: 32 IGSGAQGIVCAAYDAILERNVAIKKL--SRPFQNQTHAKRAYRELVLMKCVNHKNIIGLL 89
Query: 145 YYFLEQSDQELYLN--LIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLH 202
F Q E + + ++++ M +L Q ++ +D + ++Q+ + +LH
Sbjct: 90 NVFTPQKSLEEFQDVYIVMELMDANLCQVIQ------MELDHERMSYLLYQMLCGIKHLH 143
Query: 203 QVVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGAT 262
+ HRD+KP NI+V D L KI D G A+ + Y+ +RYYRAPE+I G
Sbjct: 144 SA-GIIHRDLKPSNIVVKSDCTL-KILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGM- 200
Query: 263 NYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTRE 309
Y +D+WS GC+M E++ + +FPG IDQ ++I+ LGTP E
Sbjct: 201 GYKENVDLWSVGCIMGEMVCHKILFPGRDYIDQWNKVIEQLGTPCPE 247
>Hs20986523 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 427
Score = 119 bits (297), Expect = 1e-26
Identities = 75/227 (33%), Positives = 120/227 (52%), Gaps = 21/227 (9%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN--------RELEIMKLISHPNLIDLK 144
+G+G+ G+V +V IKK+ R F+N REL +MK ++H N+I L
Sbjct: 32 IGSGAQGIVCAAYDAILERNVAIKKL--SRPFQNQTHAKRAYRELVLMKCVNHKNIIGLL 89
Query: 145 YYFLEQSDQELYLN--LIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLH 202
F Q E + + ++++ M +L Q ++ +D + ++Q+ + +LH
Sbjct: 90 NVFTPQKSLEEFQDVYIVMELMDANLCQVIQ------MELDHERMSYLLYQMLCGIKHLH 143
Query: 203 QVVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGAT 262
+ HRD+KP NI+V D L KI D G A+ + Y+ +RYYRAPE+I G
Sbjct: 144 SA-GIIHRDLKPSNIVVKSDCTL-KILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGM- 200
Query: 263 NYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTRE 309
Y +D+WS GC+M E++ + +FPG IDQ ++I+ LGTP E
Sbjct: 201 GYKENVDLWSVGCIMGEMVCHKILFPGRDYIDQWNKVIEQLGTPCPE 247
>YOR061w [TDK] KOG0668 Casein kinase II alpha subunit
Length = 339
Score = 118 bits (296), Expect = 1e-26
Identities = 86/296 (29%), Positives = 147/296 (49%), Gaps = 32/296 (10%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN--RELEIM-KLISHPNLIDLKYYFLE 149
+G G + VF + + VIK VL+ + K REL+I+ L PN++ L Y ++
Sbjct: 56 IGRGKYSEVFSGRCIVNNQKCVIK-VLKPVKMKKIYRELKILTNLTGGPNVVGL-YDIVQ 113
Query: 150 QSDQELYLNLIVDYMPMSLYQRLK--EFISLHQPMDRYEIKIYMFQLFKSLNYLHQVVNV 207
+D ++ P +++ +K +F +L+ +I+ Y QL +L+Y H + +
Sbjct: 114 DADSKI---------PALIFEEIKNVDFRTLYPTFKLPDIQYYFTQLLIALDYCHSM-GI 163
Query: 208 CHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGATNYTTK 267
HRD+KPQN+++DP L++ D G A+ P + SRY++ PEL+ Y
Sbjct: 164 MHRDVKPQNVMIDPTERKLRLIDWGLAEFYHPGVDYNVRVASRYHKGPELLVNLNQYDYS 223
Query: 268 IDIWSAGCVMAELLL-GQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENYSEHKFPQI 326
+D+WS GC++A ++ +P F G S DQLV+I VLGT +E+ Y H +
Sbjct: 224 LDLWSVGCMLAAIVFKKEPFFKGSSNPDQLVKIATVLGT---KELLGYLGKYGLHLPSEY 280
Query: 327 RPIPLNRIFKKETQ-----------ETIDLLYHIMKYDPNIRYSALQCMFNSTYFT 371
I + K T E +DL+ ++++YD R +A + M + + T
Sbjct: 281 DNIMRDFTKKSWTHFITSETKLAVPEVVDLIDNLLRYDHQERLTAKEAMDHKFFKT 336
>SPAC1E11.03 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 534
Score = 118 bits (296), Expect = 1e-26
Identities = 76/225 (33%), Positives = 131/225 (57%), Gaps = 17/225 (7%)
Query: 91 EIVGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKNR---ELEIMKLISHPNLIDLKYYF 147
+ +G+G+FG V R + +T + V IK + F N+ E+ I++L+++ + K +
Sbjct: 134 DTLGHGTFGQVARCQDLKTQQIVAIKVIKNKPAFYNQCVMEVSILELLNNKYDPEDKRHL 193
Query: 148 LEQSDQELYLN---LIVDYMPMSLYQRLKE--FISLHQPMDRYEIKIYMFQLFKSLNYLH 202
+ DQ ++ N L+ + + ++LY+ +K+ F LH + ++ + QL + L
Sbjct: 194 IRLYDQFMHKNHLCLVFELLSINLYELIKQNQFRGLHLSL----VRSFATQLLSCTSLLK 249
Query: 203 QVVNVCHRDIKPQNILV-DPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGA 261
Q + H D+KP+NIL+ D + ++K+ D GSA + +YI SR+YR+PE+I G
Sbjct: 250 QA-RIIHCDLKPENILLQDLSSPIVKVIDFGSA--CHERQTVYTYIQSRFYRSPEVILGL 306
Query: 262 TNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTP 306
+Y ID+WS GC++AEL LG P+FPG S+ +QL I+ +LG P
Sbjct: 307 -HYNCGIDMWSLGCILAELFLGLPLFPGNSEYNQLCRIVDMLGNP 350
>7294866 [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 531
Score = 118 bits (296), Expect = 1e-26
Identities = 97/315 (30%), Positives = 157/315 (49%), Gaps = 39/315 (12%)
Query: 93 VGNGSFGVVFRTKVKET--GEDVVIKKVLQDRRFKN--RELEIMKLISHPNLIDLKYYFL 148
VG G++G V++ K KET G++ +K++ + RE+ +++ + H N+I L FL
Sbjct: 104 VGRGTYGHVYKAKWKETSDGKEYALKQIDGTGLSMSACREIALLRELKHQNVITLIRVFL 163
Query: 149 EQSDQELYLNLIVDYMPMSLYQRLK-----EFISLHQPMDRYEIKIYMFQLFKSLNYLHQ 203
+D++++L ++DY L+ +K + + R +K ++Q+ ++YLH
Sbjct: 164 SHNDRKVFL--LIDYAEHDLWHIIKFHRAAKATKKQVVVPRGMVKSLLYQILDGIHYLHS 221
Query: 204 VVNVCHRDIKPQNILVDPDTL---LLKICDLGSAK----QLKPNEPNVSYICSRYYRAPE 256
V HRD+KP NILV D +KI D+G A+ LKP + + +YRAPE
Sbjct: 222 NW-VLHRDLKPANILVMGDGNERGRVKIADMGFARLFNAPLKPLADLDPVVVTFWYRAPE 280
Query: 257 LIFGATNYTTKIDIWSAGCVMAELLLGQPIFPGESK---------IDQLVEIIKVLGTPT 307
L+ GA +YT IDIW+ GC+ AELL +PIF + DQL I V+G P
Sbjct: 281 LLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPQ 340
Query: 308 R---EEICSMNENYS---EHKFPQIRPIPLNRIFK----KETQETIDLLYHIMKYDPNIR 357
E+I M E+++ + K L + + K + LL ++ DPN R
Sbjct: 341 DKDWEDIKKMPEHHTLTKDFKRSTYSTCSLAKYMERHKIKPDSKAFHLLQKLLLMDPNKR 400
Query: 358 YSALQCMFNSTYFTD 372
++ Q M YF +
Sbjct: 401 ITSEQAM-QDQYFQE 414
>Hs4502741 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 326
Score = 118 bits (295), Expect = 2e-26
Identities = 86/292 (29%), Positives = 145/292 (49%), Gaps = 18/292 (6%)
Query: 93 VGNGSFGVVFRTK-VKETGEDVVIKKVLQDRRFKNRELEIMKLIS---------HPNLID 142
+G G++G VF+ + +K G V +K+V + L ++ ++ HPN++
Sbjct: 19 IGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLRHLETFEHPNVVR 78
Query: 143 L-KYYFLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYL 201
L + ++D+E L L+ +++ L L + P + IK MFQL + L++L
Sbjct: 79 LFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTET--IKDMMFQLLRGLDFL 136
Query: 202 HQVVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGA 261
H V HRD+KPQNILV + K+ D G A+ S + + +YRAPE++
Sbjct: 137 HSH-RVVHRDLKPQNILVTSSGQI-KLADFGLARIYSFQMALTSVVVTLWYRAPEVLL-Q 193
Query: 262 TNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENYSEH 321
++Y T +D+WS GC+ AE+ +P+F G S +DQL +I+ V+G P EE +
Sbjct: 194 SSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLP-GEEDWPRDVALPRQ 252
Query: 322 KFPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSALQCMFNSTYFTDI 373
F P+ + + DLL + ++P R SA + + YF D+
Sbjct: 253 AFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSAL-SHPYFQDL 303
>CE17321 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 360
Score = 118 bits (295), Expect = 2e-26
Identities = 88/304 (28%), Positives = 151/304 (48%), Gaps = 42/304 (13%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIK--KVLQDRRFKNRELEIMK-LISHPNLIDLKYYFLE 149
+G G + VF T E VV+K K ++ ++ K RE++I++ L N+I L
Sbjct: 44 LGRGKYSEVFEGFKMSTDEKVVVKILKPVKKKKIK-REIKILENLRGGTNIITL------ 96
Query: 150 QSDQELYLNLIVDYM---PMSLYQRLK--EFISLHQPMDRYEIKIYMFQLFKSLNYLHQV 204
L+++ D + P +++ + +F L+Q + Y+I+ Y+++L K+L++ H
Sbjct: 97 -------LDVVKDPISRTPALIFEHVNNSDFKQLYQTLSDYDIRYYLYELLKALDFCHSQ 149
Query: 205 VNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGATNY 264
+ HRD+KP N+++D + L++ D G A+ P + + SRY++ PEL+ Y
Sbjct: 150 -GIMHRDVKPHNVMIDAEKRELRLIDWGLAEFYHPRQDYNVRVASRYFKGPELLVDYQCY 208
Query: 265 TTKIDIWSAGCVMAELLL-GQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENYSEHKF 323
+D+WS GC++A ++ +P F G DQLV I KVLGT +E+ Y
Sbjct: 209 DYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGT---DELYEYIARYHIDLD 265
Query: 324 PQIRPIPLNRIFKKE-------------TQETIDLLYHIMKYDPNIRYSALQCMFNSTYF 370
P+ I L R +K T E +D L +++YD R +A + M YF
Sbjct: 266 PRFNDI-LGRHSRKRWERFIHAENQHLVTPEALDFLDKLLRYDHAERLTAQEAM-GHEYF 323
Query: 371 TDIV 374
+V
Sbjct: 324 RPVV 327
>YKL161c [T] KOG0660 Mitogen-activated protein kinase
Length = 433
Score = 117 bits (292), Expect = 4e-26
Identities = 89/289 (30%), Positives = 149/289 (50%), Gaps = 35/289 (12%)
Query: 93 VGNGSFGVVFRTKVKETGED--VVIKKVLQDRRFKN--------RELEIMK-LISHPNLI 141
+G GS ++ + E+ E+ V I+K+ F N REL++++ L HPN++
Sbjct: 29 IGRGSHSLICSSTYTESNEETHVAIRKI--PNAFGNKLSCKRTLRELKLLRHLRGHPNIV 86
Query: 142 DLKYYFLEQSDQELYLNLIVDYMPMSLYQRLKE-----FISLHQPMDRYEIKIYMFQLFK 196
+L +D Y N ++ + LY+ L E I Q ++ + +++Q+
Sbjct: 87 -----WLFDTDIVFYPNGALN--GVYLYEELMECDLSQIIRSEQRLEDAHFQSFIYQILC 139
Query: 197 SLNYLHQVVNVCHRDIKPQNILVDPDTLLLKICDLGSA----KQLKPNEPNVS-YICSRY 251
+L Y+H NV H D+KP+N+LV+ D L KIC+ G + + K N+ + YI S +
Sbjct: 140 ALKYIHSA-NVLHCDLKPKNLLVNSDCQL-KICNFGLSCSYSENHKVNDGFIKGYITSIW 197
Query: 252 YRAPELIFGATNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTP---TR 308
Y+APE++ T +DIWS GC++AELL +P+F G+ +D L I+++LGTP T
Sbjct: 198 YKAPEILLNYQECTKAVDIWSTGCILAELLGRKPMFEGKDYVDHLNHILQILGTPPEETL 257
Query: 309 EEICSMNENYSEHKFPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIR 357
+EI S +F I I E ++LL ++++DP R
Sbjct: 258 QEIASQKVYNYIFQFGNIPGRSFESILPGANPEALELLKKMLEFDPKKR 306
>SPBC8D2.19 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 559
Score = 117 bits (292), Expect = 4e-26
Identities = 81/300 (27%), Positives = 153/300 (51%), Gaps = 37/300 (12%)
Query: 93 VGNGSFGVVFRTKVKETG---EDVVIKKVLQDRRFKNRE--------LEIMKLISHPNLI 141
+G+GSFG V+ + KE E V +KK+ + K + L + K+ HP LI
Sbjct: 27 LGDGSFGTVYLAQRKEKNGLYETVAVKKLKNSSKPKPKHELLKLRESLALRKISKHPCLI 86
Query: 142 DLKYYFLEQSDQELYLNLIVDYMPMSLYQRLKEFIS-LHQPMDRYEIKIYMFQLFKSLNY 200
DL F+ D + L++++M +L+Q K L + I + Q+ + +
Sbjct: 87 DLLETFM---DPYRNIFLVMEFMDCNLFQLFKRRQGRLFTKETAFNI---LLQIISGIEH 140
Query: 201 LHQVVNVCHRDIKPQNILVD-------PDTLLLKICDLGSAKQLKPNEPNVSYICSRYYR 253
+H+ HRDIKP+NILV +K+ D G A+ ++P Y+ +R+YR
Sbjct: 141 IHKH-GFMHRDIKPENILVKRISPKPISSRYSIKLGDFGLARPSVSSDPLTEYVSTRWYR 199
Query: 254 APELIFGATNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICS 313
APEL+ + +Y +D+++ GC++ E+ +P+FPG ++ DQL + ++LG P +E+ +
Sbjct: 200 APELLLRSGSYNHSVDLYAFGCIVFEIYSLKPLFPGRNETDQLNRVCEILGNPGIDELDT 259
Query: 314 MNENYSEHK---------FPQIRPIPLNRIFKKETQE-TIDLLYHIMKYDPNIRYSALQC 363
++ +S+ K P +P P+ ++ + E ++ ++ ++P++R +A C
Sbjct: 260 LH-YWSQAKELAKRLGFMLPPTKPYPIQKLLPQNCPEGHAKMIPCLLAWNPDVRPTAKYC 318
>Hs5921999 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 589
Score = 116 bits (290), Expect = 7e-26
Identities = 91/313 (29%), Positives = 163/313 (52%), Gaps = 26/313 (8%)
Query: 92 IVGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKNR---ELEIMKLISHPNLIDLKYYFL 148
++G GSFG V + +T E V IK + + F N+ EL +++L++ + ++KYY +
Sbjct: 116 LIGKGSFGQVVKAYDHQTQELVAIKIIKNKKAFLNQAQIELRLLELMNQHDT-EMKYYIV 174
Query: 149 EQSDQELYLN---LIVDYMPMSLYQRLKE--FISLHQPMDRYEIKIYMFQLFKSLNYLHQ 203
++ N L+ + + +LY L+ F + + R + QL +L +L
Sbjct: 175 HLKRHFMFRNHLCLVFELLSYNLYDLLRNTHFRGVSLNLTRKLAQ----QLCTALLFLAT 230
Query: 204 V-VNVCHRDIKPQNILV-DPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGA 261
+++ H D+KP+NIL+ +P +KI D GS+ QL + YI SR+YR+PE++ G
Sbjct: 231 PELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQL--GQRIYQYIQSRFYRSPEVLLG- 287
Query: 262 TNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENYSEH 321
T Y ID+WS GC++ E+ G+P+F G +++DQ+ I++VLG P +++
Sbjct: 288 TPYDLAIDMWSLGCILVEMHTGEPLFSGSNEVDQMNRIVEVLGIP---PAAMLDQAPKAR 344
Query: 322 KFPQIRPIPLNRIFKKETQE-TIDLLYHIMKYDPNIRYSALQCMFNSTY--FTDIVSNTG 378
K+ +P + T+E DL+ +++Y+P R S L + + + D +NTG
Sbjct: 345 KY--FERLPGGGWTLRRTKELRKDLVLRMLEYEPAARISPLGALQHGFFRRTADEATNTG 402
Query: 379 SDSNLSLIDSLPL 391
+ + PL
Sbjct: 403 PAGSSASTSPAPL 415
>Hs4502745 [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 464
Score = 115 bits (289), Expect = 9e-26
Identities = 94/315 (29%), Positives = 153/315 (47%), Gaps = 38/315 (12%)
Query: 93 VGNGSFGVVFRTKVKE--TGEDVVIKKVLQDRRFKN--RELEIMKLISHPNLIDLKYYFL 148
VG G++G V++ K K+ +D +K++ + RE+ +++ + HPN+I L+ FL
Sbjct: 27 VGRGTYGHVYKAKRKDGKDDKDYALKQIEGTGISMSACREIALLRELKHPNVISLQKVFL 86
Query: 149 EQSDQELYLNLIVDYMPMSL-----YQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQ 203
+D++++L + DY L + R + + R +K ++Q+ ++YLH
Sbjct: 87 SHADRKVWL--LFDYAEHDLWHIIKFHRASKANKKPVQLPRGMVKSLLYQILDGIHYLHA 144
Query: 204 VVNVCHRDIKPQNILV---DPDTLLLKICDLGSAK----QLKPNEPNVSYICSRYYRAPE 256
V HRD+KP NILV P+ +KI D+G A+ LKP + + +YRAPE
Sbjct: 145 NW-VLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPE 203
Query: 257 LIFGATNYTTKIDIWSAGCVMAELLLGQPIFPGESK---------IDQLVEIIKVLGTPT 307
L+ GA +YT IDIW+ GC+ AELL +PIF + DQL I V+G P
Sbjct: 204 LLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPA 263
Query: 308 R---EEICSMNE------NYSEHKFPQIRPIPLNRIFK-KETQETIDLLYHIMKYDPNIR 357
E+I M E ++ + + I K K + LL ++ DP R
Sbjct: 264 DKDWEDIKKMPEHSTLMKDFRRNTYTNCSLIKYMEKHKVKPDSKAFHLLQKLLTMDPIKR 323
Query: 358 YSALQCMFNSTYFTD 372
++ Q M + + D
Sbjct: 324 ITSEQAMQDPYFLED 338
>ECU05g1510 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 319
Score = 115 bits (288), Expect = 1e-25
Identities = 89/280 (31%), Positives = 141/280 (49%), Gaps = 19/280 (6%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN-RELEIMKLISHPNLIDLKYYFLEQS 151
+G G + VF + + E +VIK + R+ K RE+ I++ +SH N+I L ++
Sbjct: 43 MGRGKYSEVFEGR--KDREKIVIKALKPVRKAKICREVLILRNLSHKNIIKLMDVVVDPE 100
Query: 152 DQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVVNVCHRD 211
Q +LI +Y+ Y ++ E + +I Y Q+ +L+Y H + + HRD
Sbjct: 101 SQ--IYSLIFEYIEHEDYAKIFEKLCYK------DIVEYSRQILSALSYCHSM-GIIHRD 151
Query: 212 IKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGATNYTTKIDIW 271
IKPQN++++ LKI D G A+ P + + SRYY+ PEL+ Y +DIW
Sbjct: 152 IKPQNMVINQARRELKIIDWGLAEFYHPKKEYSVRVASRYYKGPELLVDYPYYDYSLDIW 211
Query: 272 SAGCVMAELLL-GQPIFPGESKIDQLVEIIKVLG-TPTREEICSMNENYSEHKFPQIRPI 329
S GCV+AEL+ +P F GES DQLV+I ++LG T ++ + K+ +
Sbjct: 212 SFGCVLAELVFKKRPFFHGESNSDQLVKIARILGYTHLKKYVRKYKMAPLNPKYEGVGER 271
Query: 330 PLNRIFKKETQ-----ETIDLLYHIMKYDPNIRYSALQCM 364
L F + IDLL I+ YD R +A +C+
Sbjct: 272 VLLSSFTPPGKTGLYTNAIDLLEKILIYDHQDRPTADECL 311
>At3g50000 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 333
Score = 115 bits (288), Expect = 1e-25
Identities = 82/296 (27%), Positives = 148/296 (49%), Gaps = 28/296 (9%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFK-NRELEIMK-LISHPNLIDLKYYFLEQ 150
VG G + VF E +IK + ++ K RE++I++ L PN++ L +Q
Sbjct: 40 VGRGKYSEVFEGINMNNNEKCIIKILKPVKKKKIRREIKILQNLCGGPNIVKLLDVVRDQ 99
Query: 151 SDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVVNVCHR 210
+ +LI +Y+ + +F L+ + Y+I+ Y+++L K+L++ H + HR
Sbjct: 100 HSKTP--SLIFEYVNST------DFKVLYPTLTDYDIRYYIYELLKALDFCHSQ-GIMHR 150
Query: 211 DIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGATNYTTKIDI 270
D+KP N+++D + L++ D G A+ P + + SRY++ PEL+ +Y +D+
Sbjct: 151 DVKPHNVMIDHELRKLRLIDWGLAEFYHPGKEYNVRVASRYFKGPELLVDLQDYDYSLDM 210
Query: 271 WSAGCVMAELLL-GQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENYSEHKFPQIRPI 329
WS GC+ A ++ +P F G DQLV+I KVLGT +E+ + Y Q+ +
Sbjct: 211 WSLGCMFAGMIFRKEPFFYGHDNQDQLVKIAKVLGT---DELNAYLNKYQLELDTQLEAL 267
Query: 330 -------PLNRIFKKETQ-----ETIDLLYHIMKYDPNIRYSALQCMFNSTYFTDI 373
P ++ + + E ID L +++YD R +A + M + YF +
Sbjct: 268 VGRHSRKPWSKFINADNRHLVSPEAIDYLDKLLRYDHQDRLTAKEAMAH-PYFAQV 322
>YPL042c [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 555
Score = 115 bits (287), Expect = 2e-25
Identities = 114/411 (27%), Positives = 187/411 (44%), Gaps = 50/411 (12%)
Query: 22 TNDKNAGFETEMDSILPSDDLKQGSLHSKNSHGNDVKIVPDEDEVITRRTVVKGHSNPEE 81
TN K F++ S D++ + + + D + P + T R V H N ++
Sbjct: 111 TNAKIPQFDSTQPKSSSSMDMQANTNALRRNLLKDEGVTPGR--IRTTREDVSPHYNSQK 168
Query: 82 SVVISCGTPEIVGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKNRELEIMKLISHPNLI 141
+I P V F + + K ++ G + + + RE+ + + + + +L
Sbjct: 169 QTLIK--KPLTV----FYAIKKFKTEKDGVEQLHYTGISQSAC--REMALCRELHNKHLT 220
Query: 142 DLKYYFLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEI-----KIYMFQLFK 196
L FLE+ ++++ +Y L Q I H ++ I + M+QL
Sbjct: 221 TLVEIFLERK----CVHMVYEYAEHDLLQ----IIHFHSHPEKRMIPPRMVRSIMWQLLD 272
Query: 197 SLNYLHQVVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQ----LKPNEPNVSYICSRYY 252
++YLHQ V HRD+KP NI+V D + KI DLG A++ L+ + + +Y
Sbjct: 273 GVSYLHQNW-VLHRDLKPANIMVTIDGCV-KIGDLGLARKFHNMLQTLYTGDKVVVTIWY 330
Query: 253 RAPELIFGATNYTTKIDIWSAGCVMAELLLGQPIFPGES-----------KIDQLVEIIK 301
RAPEL+ GA +YT +D+WS GC+ AEL+ QPIF GE +++QL I++
Sbjct: 331 RAPELLLGARHYTPAVDLWSVGCIFAELIGLQPIFKGEEAKLDSKKTVPFQVNQLQRILE 390
Query: 302 VLGTPTREEICSMNENYSEH----KFPQIRPIPLNRIFKK--ETQETIDLLYHIMKYDPN 355
VLGTP ++I E Y E+ KFP+ R + + LLYH++ YDP
Sbjct: 391 VLGTPD-QKIWPYLEKYPEYDQITKFPKYRDNLATWYHSAGGRDKHALSLLYHLLNYDPI 449
Query: 356 IRYSALQCMFNSTYFT--DIVSNTGSDSNLSLIDSLPLLHFEESELQGLSS 404
R A + YFT DI + L+ +H ++++ L S
Sbjct: 450 KRIDAFNAL-EHKYFTESDIPVSENVFEGLTYKYPARRIHTNDNDIMNLGS 499
>YJL141c [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 807
Score = 115 bits (287), Expect = 2e-25
Identities = 80/223 (35%), Positives = 125/223 (55%), Gaps = 13/223 (5%)
Query: 91 EIVGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKNR---ELEIMKLISHPNLIDLKYYF 147
+I+G G+FG V + + T E + +K V + + E +I++L++ K++F
Sbjct: 373 DILGQGTFGQVVKCQNLLTKEILAVKVVKSRTEYLTQSITEAKILELLNQKIDPTNKHHF 432
Query: 148 LEQSDQELYLN---LIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQV 204
L D ++ N L+ + + +LY+ LK+ + + I+ + Q+ SL L +
Sbjct: 433 LRMYDSFVHKNHLCLVFELLSNNLYELLKQ--NKFHGLSIQLIRTFTTQILDSLCVLKES 490
Query: 205 VNVCHRDIKPQNILV-DPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGATN 263
+ H D+KP+NIL+ PD LKI D GS+ + +YI SR+YRAPE+I G
Sbjct: 491 -KLIHCDLKPENILLCAPDKPELKIIDFGSS--CEEARTVYTYIQSRFYRAPEIILGIP- 546
Query: 264 YTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTP 306
Y+T ID+WS GC++AEL LG PIFPG S+ +QL II LG P
Sbjct: 547 YSTSIDMWSLGCIVAELFLGIPIFPGASEYNQLTRIIDTLGYP 589
>ECU08g1790 [D] KOG0600 Cdc2-related protein kinase
Length = 309
Score = 115 bits (287), Expect = 2e-25
Identities = 90/320 (28%), Positives = 155/320 (48%), Gaps = 38/320 (11%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQDRRF-----KNRELEIMKLISHPNLIDLKYYF 147
VG G+FG V++++ G IKK+ DR RE+++ K + + ++I L
Sbjct: 10 VGEGAFGQVYKSRRTSDGAVFAIKKMPVDRETGFPFTAIREIKLCKSVINKHIIGLDEIV 69
Query: 148 LEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVVNV 207
E+ ++ ++++YMP L L L +I+ QL ++++ +H + +
Sbjct: 70 FEEG----FIFVVLEYMPYDLTGLLASGAKLSTD----QIRSITSQLIEAVSSMHGM-GL 120
Query: 208 CHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGATNYTTK 267
HRDIKP NIL+D +L K+ D G +++ N +C+ +YRAPEL+ G T+Y+ K
Sbjct: 121 VHRDIKPSNILLDCHGML-KLTDFGLTREISGMMTN--RVCTLWYRAPELLLGETSYSLK 177
Query: 268 IDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENYSEHKFPQIR 327
+D WS GC+M E+ LG+P + G ++ Q+ I + LG P ++K+ +
Sbjct: 178 VDAWSVGCIMLEMRLGRPPYRGSDEVSQIKLIFEELGIP-----------QDKYKWSDLL 226
Query: 328 PIPLNRIFKKETQETIDLLY-HIMKYDPNIRYSALQCM--------FNSTYFTDIVSNTG 378
+ + + T+E I Y H+ + S C+ NS YFT I S+
Sbjct: 227 DVDIYS-KSRSTEEIIAERYGHLFDEEELKVLSGFLCLTSRKRLSVANSRYFTVISSHKN 285
Query: 379 SDSNLSLIDSLPLLHFEESE 398
+ LS ++ L E E
Sbjct: 286 TYIPLSFEEAHELYTKERKE 305
>7298142 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 722
Score = 114 bits (286), Expect = 2e-25
Identities = 77/229 (33%), Positives = 128/229 (55%), Gaps = 22/229 (9%)
Query: 91 EIVGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKNR---ELEIMKLI-------SHPNL 140
E++G GSFG V R +T V IK + +RF N+ EL I+ + SH +
Sbjct: 202 EVIGKGSFGQVIRALDHKTNTHVAIKIIRNKKRFLNQAVVELNILDELREKDADGSHNVI 261
Query: 141 IDLKYYFLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNY 200
L Y + + +L + + M ++LY+ +K+ + + I+ + + K L
Sbjct: 262 HMLDYTYFRK-----HLCITFELMSLNLYELIKK--NNYNGFSMSLIRRFCNSIVKCLRL 314
Query: 201 LHQVVNVCHRDIKPQNILVDP-DTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIF 259
L++ N+ H D+KP+NIL+ + +K+ D GS+ + + +YI SR+YR+PE+I
Sbjct: 315 LYKE-NIIHCDLKPENILLKQRGSSSIKVIDFGSSCYV--DRKIYTYIQSRFYRSPEVIL 371
Query: 260 GATNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTR 308
G Y T ID+WS GC++AEL G P+FPGE++++QL I++VLG P +
Sbjct: 372 GL-QYGTAIDMWSLGCILAELYTGFPLFPGENEVEQLACIMEVLGLPPK 419
>Hs5922004 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 601
Score = 114 bits (284), Expect = 3e-25
Identities = 73/239 (30%), Positives = 129/239 (53%), Gaps = 16/239 (6%)
Query: 79 PEESVVISCGTPEIVGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKNRELEIMKLISHP 138
P + V +++G GSFG V + + + V +K V ++RF + E ++++ H
Sbjct: 214 PHDHVAYRYEVLKVIGKGSFGQVVKAYDHKVHQHVALKMVRNEKRFHRQAAEEIRILEHL 273
Query: 139 NLIDLK-----YYFLEQSDQELYLNLIVDYMPMSLYQRLKE--FISLHQPMDRYEIKIYM 191
D + LE ++ + + + M+LY+ +K+ F P+ ++ +
Sbjct: 274 RKQDKDNTMNVIHMLENFTFRNHICMTFELLSMNLYELIKKNKFQGFSLPL----VRKFA 329
Query: 192 FQLFKSLNYLHQVVNVCHRDIKPQNILVDPDTLL-LKICDLGSAKQLKPNEPNVSYICSR 250
+ + L+ LH+ + H D+KP+NIL+ +K+ D GS+ ++ +YI SR
Sbjct: 330 HSILQCLDALHKN-RIIHCDLKPENILLKQQGRSGIKVIDFGSS--CYEHQRVYTYIQSR 386
Query: 251 YYRAPELIFGATNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTRE 309
+YRAPE+I GA Y ID+WS GC++AELL G P+ PGE + DQL +I++LG P+++
Sbjct: 387 FYRAPEVILGA-RYGMPIDMWSLGCILAELLTGYPLLPGEDEGDQLACMIELLGMPSQK 444
>Hs4503427 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 528
Score = 114 bits (284), Expect = 3e-25
Identities = 73/239 (30%), Positives = 129/239 (53%), Gaps = 16/239 (6%)
Query: 79 PEESVVISCGTPEIVGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKNRELEIMKLISHP 138
P + V +++G GSFG V + + + V +K V ++RF + E ++++ H
Sbjct: 141 PHDHVAYRYEVLKVIGKGSFGQVVKAYDHKVHQHVALKMVRNEKRFHRQAAEEIRILEHL 200
Query: 139 NLIDLK-----YYFLEQSDQELYLNLIVDYMPMSLYQRLKE--FISLHQPMDRYEIKIYM 191
D + LE ++ + + + M+LY+ +K+ F P+ ++ +
Sbjct: 201 RKQDKDNTMNVIHMLENFTFRNHICMTFELLSMNLYELIKKNKFQGFSLPL----VRKFA 256
Query: 192 FQLFKSLNYLHQVVNVCHRDIKPQNILVDPDTLL-LKICDLGSAKQLKPNEPNVSYICSR 250
+ + L+ LH+ + H D+KP+NIL+ +K+ D GS+ ++ +YI SR
Sbjct: 257 HSILQCLDALHKN-RIIHCDLKPENILLKQQGRSGIKVIDFGSS--CYEHQRVYTYIQSR 313
Query: 251 YYRAPELIFGATNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTRE 309
+YRAPE+I GA Y ID+WS GC++AELL G P+ PGE + DQL +I++LG P+++
Sbjct: 314 FYRAPEVILGA-RYGMPIDMWSLGCILAELLTGYPLLPGEDEGDQLACMIELLGMPSQK 371
>Hs17452757 [UT] KOG0662 Cyclin-dependent kinase CDK5
Length = 366
Score = 114 bits (284), Expect = 3e-25
Identities = 98/294 (33%), Positives = 150/294 (50%), Gaps = 39/294 (13%)
Query: 91 EIVGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN------RELEIMKLISHPNLIDLK 144
E +G G++G VF+ K ET E V +K V D RE+ ++K + H N++ L
Sbjct: 79 EKIGEGTYGTVFKAKNWETHEIVALKWVRLDDNDDGVPSSALREICLLKELKHKNIVRL- 137
Query: 145 YYFLEQSDQELYLNLIVDYMPMSLYQRLKEFI-SLHQPMDRYEIKIYMFQLFKSLNYLHQ 203
+ L SD++L L+ + +Q LK++ S + +D +K ++FQL K L + H
Sbjct: 138 -HDLLHSDKKL--TLVFKFC----HQHLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHS 190
Query: 204 VVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAP--ELIFGA 261
NV RD+KPQN+L++ + L K+ D G SR + P + FGA
Sbjct: 191 R-NVLRRDLKPQNLLINRNGEL-KLADFG---------------LSRAFGIPICYVFFGA 233
Query: 262 TNYTTKIDIWSAGCVMAELL-LGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENYSE 320
Y+T ID+WSAGC+ AEL G P+FPG DQL I +LG T+E+ SM + +
Sbjct: 234 KLYSTSIDLWSAGCIFAELANAGWPLFPGNDVDDQLKRIFWLLGMLTKEQWPSMTK-LPD 292
Query: 321 HKFPQIRP--IPLNRIFKKETQETIDLLYHIMKYDPNIRYSALQCMFNSTYFTD 372
+K + P L I K + DLL +++K +P SA + + YF+D
Sbjct: 293 YKLYPLYPATTSLVNIVPKLSATGRDLLQNLLKCNPCQCISAEEAL-QYPYFSD 345
>Hs4503097 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 350
Score = 113 bits (283), Expect = 5e-25
Identities = 87/301 (28%), Positives = 147/301 (47%), Gaps = 36/301 (11%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIK--KVLQDRRFKNRELEIMK-LISHPNLIDLKYYFLE 149
+G G + VF E VV+K K ++ ++ K RE++I++ L N+I L +
Sbjct: 46 LGRGKYSEVFEAINITNNERVVVKILKPVKKKKIK-REVKILENLRGGTNIIKLIDTVKD 104
Query: 150 QSDQELYLNLIVDYMPMSLYQRLK--EFISLHQPMDRYEIKIYMFQLFKSLNYLHQVVNV 207
V P +++ + +F L+Q + ++I+ YM++L K+L+Y H +
Sbjct: 105 P----------VSKTPALVFEYINNTDFKQLYQILTDFDIRFYMYELLKALDYCHSK-GI 153
Query: 208 CHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGATNYTTK 267
HRD+KP N+++D L++ D G A+ P + + SRY++ PEL+ Y
Sbjct: 154 MHRDVKPHNVMIDHQQKKLRLIDWGLAEFYHPAQEYNVRVASRYFKGPELLVDYQMYDYS 213
Query: 268 IDIWSAGCVMAELLL-GQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENYSEHKFPQI 326
+D+WS GC++A ++ +P F G+ DQLV I KVLGT EE+ + Y P
Sbjct: 214 LDMWSLGCMLASMIFRREPFFHGQDNYDQLVRIAKVLGT---EELYGYLKKYHIDLDPHF 270
Query: 327 RPIPLNRIFKKE-------------TQETIDLLYHIMKYDPNIRYSALQCMFNSTYFTDI 373
I L + +K + E +DLL +++YD R +A + M YF +
Sbjct: 271 NDI-LGQHSRKRWENFIHSENRHLVSPEALDLLDKLLRYDHQQRLTAKEAM-EHPYFYPV 328
Query: 374 V 374
V
Sbjct: 329 V 329
>Hs20551615 [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 358
Score = 113 bits (283), Expect = 5e-25
Identities = 88/289 (30%), Positives = 148/289 (50%), Gaps = 44/289 (15%)
Query: 93 VGNGSFGVVFRTKVKETGED--VVIKKVLQDRRFKN--RELEIMKLISHPNLIDLKYYFL 148
VG G++G V++ + K+ ++ +K++ + RE+ +++ + HPN+I L+ FL
Sbjct: 27 VGRGTYGHVYKARRKDGKDEKEYALKQIEGTGISMSACREIALLRELKHPNVIALQKVFL 86
Query: 149 EQSDQELYLNLIVDYMPMSLYQRLKEFISLH---QPMD--RYEIKIYMFQLFKSLNYLHQ 203
SD++++L + DY L+ +K + +PM R +K ++Q+ ++YLH
Sbjct: 87 SHSDRKVWL--LFDYAEHDLWHIIKFHRASKANKKPMQLPRSMVKSLLYQILDGIHYLHA 144
Query: 204 VVNVCHRDIKPQNILV---DPDTLLLKICDLGSAK----QLKPNEPNVSYICSRYYRAPE 256
V HRD+KP NILV P+ +KI D+G A+ LKP + + +YRAPE
Sbjct: 145 NW-VLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPE 203
Query: 257 LIFGATNYTTKIDIWSAGCVMAELLLGQPIFPGESK---------IDQLVEIIKVLGTPT 307
L+ GA +YT IDIW+ GC+ AELL +PIF + DQL I V+G P
Sbjct: 204 LLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPFHHDQLDRIFSVMGFP- 262
Query: 308 REEICSMNENYSEHKFPQIRPIP----LNRIFKKETQETIDLLYHIMKY 352
++ + IR +P L + F++ T L+ ++ K+
Sbjct: 263 -----------ADKDWEDIRKMPEYPTLQKDFRRTTYANSSLIKYMEKH 300
>Hs5922001 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 601
Score = 113 bits (282), Expect = 6e-25
Identities = 91/323 (28%), Positives = 165/323 (50%), Gaps = 34/323 (10%)
Query: 92 IVGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKNR---ELEIMKLISHPNLIDLKYYFL 148
++G GSFG V + +T E V IK + + F N+ EL +++L++ + ++KYY +
Sbjct: 116 LIGKGSFGQVVKAYDHQTQELVAIKIIKNKKAFLNQAQIELRLLELMNQHDT-EMKYYIV 174
Query: 149 EQSDQELYLN---LIVDYMPMSLYQRLKE--FISLHQPMDRYEIKIYMFQLFKSLNYLHQ 203
++ N L+ + + +LY L+ F + + R + QL +L +L
Sbjct: 175 HLKRHFMFRNHLCLVFELLSYNLYDLLRNTHFRGVSLNLTRKLAQ----QLCTALLFLAT 230
Query: 204 V-VNVCHRDIKPQNILV-DPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGA 261
+++ H D+KP+NIL+ +P +KI D GS+ QL + YI SR+YR+PE++ G
Sbjct: 231 PELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQL--GQRIYQYIQSRFYRSPEVLLG- 287
Query: 262 TNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENYSEH 321
T Y ID+WS GC++ E+ G+P+F G +++DQ+ I++VLG P +++
Sbjct: 288 TPYDLAIDMWSLGCILVEMHTGEPLFSGSNEVDQMNRIVEVLGIP---PAAMLDQAPKAR 344
Query: 322 KFPQIRP-----IPLNRIFKKETQE------TIDLLYHIMKYDPNIRYSALQCMFNSTY- 369
K+ + P + + +K+ Q DL+ +++Y+P R S L + + +
Sbjct: 345 KYFERLPGGGWTLRRTKELRKDYQGPGTRRLQEDLVLRMLEYEPAARISPLGALQHGFFR 404
Query: 370 -FTDIVSNTGSDSNLSLIDSLPL 391
D +NTG + + PL
Sbjct: 405 RTADEATNTGPAGSSASTSPAPL 427
>7302908 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 317
Score = 113 bits (282), Expect = 6e-25
Identities = 88/284 (30%), Positives = 139/284 (47%), Gaps = 18/284 (6%)
Query: 92 IVGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN------RELEIMKLIS---HPNLID 142
I+G G++G V+R + TG V +KKV RE+ ++K ++ H N++
Sbjct: 31 IIGEGAYGTVYRARDVITGNIVALKKVRISLNENGVPMSTLREISLLKQLNASNHANIVK 90
Query: 143 LKYY--FLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNY 200
L FLE+ Q L L L+ +++ L + M I+ +L +++
Sbjct: 91 LYEVCQFLERDGQLLIL-LVFEHVEQDLSDLIDRLPK--SGMSPPTIQRLSRELLTGVDF 147
Query: 201 LHQVVNVCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFG 260
LH + HRD+KPQN+LV L KI D G AK S + + +YRAPE++
Sbjct: 148 LHSH-RIIHRDLKPQNLLVSSQGHL-KIADFGLAKTYGSEMKLTSVVVTLWYRAPEVLL- 204
Query: 261 ATNYTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENYSE 320
A Y + +DIWSA C++ E+ + +FPG S+ +QL I ++ G PT ++ E
Sbjct: 205 AQPYNSTVDIWSAACIIFEMFNRRALFPGTSEKNQLDRIFELTGRPTEQQWPQTISVALE 264
Query: 321 HKFPQIRPIPLNRIFKKETQETIDLLYHIMKYDPNIRYSALQCM 364
H FPQ P + DLL ++ YD ++R SAL C+
Sbjct: 265 H-FPQRHPKRPKDFCPHLCKYADDLLNKMLSYDLHLRPSALACL 307
>ECU02g1450 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 308
Score = 112 bits (281), Expect = 8e-25
Identities = 71/249 (28%), Positives = 127/249 (50%), Gaps = 9/249 (3%)
Query: 113 VVIKKVLQDRRFKNRELEIMKLISHPNLIDLKYY--FLEQSDQELYLNLIVDYMPMSLYQ 170
V IKK+ + + E+ ++ I ID KY ++ + ++++++Y+ +L
Sbjct: 43 VAIKKIKPTKYTQGHEISAIREIKSLKRIDSKYVVRLIDTFVYDKCVHIVLEYVETNLEN 102
Query: 171 RLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVVNVCHRDIKPQNILVDPDTLLLKICD 230
++ + P D IK ++ + + + H++ + HRDIKP NIL+ + ++ K+ D
Sbjct: 103 VIRNSDKIIMPGD---IKAWILMVLRGVYECHRLF-IIHRDIKPNNILITSEGMV-KLAD 157
Query: 231 LGSAKQLKPNEPNVSYICSRYYRAPELIFGATNYTTKIDIWSAGCVMAELLLGQPIFPGE 290
G + + +R+YRAPEL+ G+ +Y + +D+WS GCV AEL L P+F G+
Sbjct: 158 FGLTRGI--GNRMTPQAVTRWYRAPELLMGSRDYGSPVDMWSVGCVFAELFLRVPLFAGD 215
Query: 291 SKIDQLVEIIKVLGTPTREEICSMNENYSEHKFPQIRPIPLNRIFKKETQETIDLLYHIM 350
+ I QL I + LGTP E ++ F Q LN +F + + +DLL ++
Sbjct: 216 TDIQQLDMIFRALGTPVEREWPGVSTLPEFLDFQQYPKASLNGLFSAASSDALDLLEKLL 275
Query: 351 KYDPNIRYS 359
+P R S
Sbjct: 276 TLNPCNRIS 284
>CE04430 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 821
Score = 112 bits (281), Expect = 8e-25
Identities = 83/241 (34%), Positives = 130/241 (53%), Gaps = 17/241 (7%)
Query: 91 EIVGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKNR---ELEIMKLISHPNLIDLKYY- 146
E +G G+FG V + K T E V IK + + + + E+ I+ +S+ N + +
Sbjct: 126 EFLGKGTFGQVVKAWKKGTSEIVAIKILKKHPSYARQGQIEVSILSRLSNENSEEFNFVR 185
Query: 147 FLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVVN 206
E + + + L+ + + +LY LK+ + P+ I+ +FQ+ +L L +
Sbjct: 186 AFECFNHKSHTCLVFEMLEQNLYDFLKQ--NKFMPLPLNAIRPILFQVLTALLKLKSL-G 242
Query: 207 VCHRDIKPQNI-LVDPDT--LLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGATN 263
+ H D+KP+NI LVDP +K+ D GSA N +Y+ SRYYRAPE+I G
Sbjct: 243 LIHADLKPENIMLVDPQQQPYRVKVIDFGSASHRSKAVTN-TYLQSRYYRAPEIILGLP- 300
Query: 264 YTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENYSE-HK 322
+ ID+WS GCV+AEL LG P++PG S+ DQ+ II+ G P SM E+ S+ H+
Sbjct: 301 FNESIDMWSLGCVIAELFLGWPLYPGSSEYDQIRFIIQTQGLPP----TSMLESASKLHR 356
Query: 323 F 323
F
Sbjct: 357 F 357
>SPAC2F3.15 [D] KOG0600 Cdc2-related protein kinase
Length = 593
Score = 112 bits (279), Expect = 1e-24
Identities = 86/303 (28%), Positives = 147/303 (48%), Gaps = 47/303 (15%)
Query: 93 VGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKN------RELEIMKLISHPNLIDLKYY 146
+G G++G V++ TG+ V +K++ ++ RE++I++ + H N++ L
Sbjct: 283 IGEGTYGKVYKAINTVTGDLVALKRIRLEQEKDGFPITTVREVKILQRLRHKNIVRLLEI 342
Query: 147 FLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVVN 206
+E+S + ++ +YM L L P + IK Q+F++L YLH
Sbjct: 343 MVEKSS----VYMVFEYMDHDLTGVLLNSQLHFTPGN---IKHLSKQIFEALAYLHHR-G 394
Query: 207 VCHRDIKPQNILVDPDTLLLKICDLGSAKQLKPNEPNVSY---ICSRYYRAPELIFGATN 263
V HRDIK NIL++ + L K D G A+ + + +Y + + ++R PEL+ G T
Sbjct: 395 VLHRDIKGSNILLNNNGDL-KFADFGLAR-FNTSSKSANYTNRVITLWFRPPELLLGETA 452
Query: 264 YTTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTPTREEICSMNENYSEHKF 323
Y T +DIWSAGC++ EL G+P F G +I QL I ++GTP H +
Sbjct: 453 YDTAVDIWSAGCIVMELFTGKPFFQGRDEISQLEVIYDMMGTP------------DVHSW 500
Query: 324 PQIRPIPLNRIFKKETQE---------------TIDLLYHIMKYDPNIRYSALQCMFNST 368
P+++ +P + K ++ IDL ++ +P R SA + + +
Sbjct: 501 PEVKNLPWYELLKPVEEKKSRFVETFKEILSPAAIDLCQKLLALNPFCRPSAHETLMHE- 559
Query: 369 YFT 371
YFT
Sbjct: 560 YFT 562
>Hs4503429 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 553
Score = 111 bits (278), Expect = 2e-24
Identities = 73/222 (32%), Positives = 123/222 (54%), Gaps = 12/222 (5%)
Query: 91 EIVGNGSFGVVFRTKVKETGEDVVIKKVLQDRRFKNRELEIMKLISHPNLIDLK-----Y 145
+I+G GSFG V R + + V +K V ++RF + E ++++ H D
Sbjct: 178 KIIGKGSFGQVARVYDHKLRQYVALKMVRNEKRFHRQAAEEIRILEHLKKQDKTGSMNVI 237
Query: 146 YFLEQSDQELYLNLIVDYMPMSLYQRLKEFISLHQPMDRYEIKIYMFQLFKSLNYLHQVV 205
+ LE ++ + + + + LY+ +K+ + Q ++ + + +SL+ LH+
Sbjct: 238 HMLESFTFRNHVCMAFELLSIDLYELIKK--NKFQGFSVQLVRKFAQSILQSLDALHKN- 294
Query: 206 NVCHRDIKPQNILVDPD-TLLLKICDLGSAKQLKPNEPNVSYICSRYYRAPELIFGATNY 264
+ H D+KP+NIL+ K+ D GS+ + +YI SR+YRAPE+I G+ Y
Sbjct: 295 KIIHCDLKPENILLKHHGRSSTKVIDFGSS--CFEYQKLYTYIQSRFYRAPEIILGS-RY 351
Query: 265 TTKIDIWSAGCVMAELLLGQPIFPGESKIDQLVEIIKVLGTP 306
+T IDIWS C++AELL GQP+FPGE + DQL ++++LG P
Sbjct: 352 STPIDIWSFRCILAELLTGQPLFPGEDEGDQLACMMELLGMP 393
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.319 0.138 0.399
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,384,901
Number of Sequences: 60738
Number of extensions: 1178790
Number of successful extensions: 7667
Number of sequences better than 1.0e-05: 1386
Number of HSP's better than 0.0 without gapping: 289
Number of HSP's successfully gapped in prelim test: 1100
Number of HSP's that attempted gapping in prelim test: 4594
Number of HSP's gapped (non-prelim): 1535
length of query: 415
length of database: 30,389,216
effective HSP length: 109
effective length of query: 306
effective length of database: 23,768,774
effective search space: 7273244844
effective search space used: 7273244844
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)