ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI4607 good B KOG2747 Chromatin structure and dynamics Histone acetyltransferase (MYST family)
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI4607 1600261 1601217 319
(319 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YMR127c [B] KOG2747 Histone acetyltransferase (MYST family) 395 e-110
Hs14149875 [B] KOG2747 Histone acetyltransferase (MYST family) 160 3e-39
7290646 [B] KOG2747 Histone acetyltransferase (MYST family) 157 3e-38
7291743 [B] KOG2747 Histone acetyltransferase (MYST family) 148 1e-35
CE21225 [B] KOG2747 Histone acetyltransferase (MYST family) 144 2e-34
Hs5901962 [B] KOG2747 Histone acetyltransferase (MYST family) 143 3e-34
7301677 [B] KOG2747 Histone acetyltransferase (MYST family) 143 4e-34
7290469 [B] KOG2747 Histone acetyltransferase (MYST family) 142 5e-34
Hs5803098 [B] KOG2747 Histone acetyltransferase (MYST family) 142 8e-34
Hs6912512 [B] KOG2747 Histone acetyltransferase (MYST family) 140 2e-33
Hs5454128 [B] KOG2747 Histone acetyltransferase (MYST family) 140 2e-33
At5g64610 [B] KOG2747 Histone acetyltransferase (MYST family) 139 5e-33
CE23850 [B] KOG2747 Histone acetyltransferase (MYST family) 139 7e-33
At5g09740 [B] KOG2747 Histone acetyltransferase (MYST family) 135 6e-32
SPAC17G8.13c [B] KOG2747 Histone acetyltransferase (MYST family) 134 1e-31
SPAC637.12c [B] KOG2747 Histone acetyltransferase (MYST family) 132 7e-31
YBL052c [B] KOG2747 Histone acetyltransferase (MYST family) 130 2e-30
ECU10g0660 [B] KOG2747 Histone acetyltransferase (MYST family) 129 4e-30
Hs20549811 [B] KOG2747 Histone acetyltransferase (MYST family) 128 1e-29
YOR244w [B] KOG2747 Histone acetyltransferase (MYST family) 126 5e-29
CE27818 [B] KOG2747 Histone acetyltransferase (MYST family) 125 6e-29
CE06262 [B] KOG2747 Histone acetyltransferase (MYST family) 124 2e-28
7297249 [B] KOG2747 Histone acetyltransferase (MYST family) 95 1e-19
ECU09g1310 [B] KOG2747 Histone acetyltransferase (MYST family) 84 3e-16
>YMR127c [B] KOG2747 Histone acetyltransferase (MYST family)
Length = 338
Score = 395 bits (1016), Expect = e-110
Identities = 187/318 (58%), Positives = 237/318 (73%), Gaps = 9/318 (2%)
Query: 4 KPDKHNSSTEDEEIYGILDKPNIRHVQFGLNKRFATWYGSNVYFGRNKRTLGFKESNNEH 63
KP T+ E +YGIL++ NIR +QFGLNK+F+TWYGS VYF + LG E+ +
Sbjct: 28 KPSAKIKKTQKEMLYGILNERNIRQIQFGLNKKFSTWYGSAVYFDPETKRLGCSETKGQL 87
Query: 64 TAKQSPTEKKFEDQYWIDTLYVCEYCFKYTDDEAELIAHECFCRYKNKPPGRIKYRSPEY 123
++ + QYW+DTL+VCEYCFKYTDD+ + H C ++ + PG+IKY+SPEY
Sbjct: 88 SSVSN-------SQYWLDTLFVCEYCFKYTDDQTRFVGHVASCPFQYRVPGKIKYKSPEY 140
Query: 124 TIRRVKGSKHEVFCQCLCLFTKLFLDNKSVYFKVKHFEFYIVYENNSTVPMAFFSKDLYS 183
TIRRVKGSK+++FCQCLCLFTKL+LDNKS+YFKV H+EFYIVYE ST PM FFSKDL S
Sbjct: 141 TIRRVKGSKYQLFCQCLCLFTKLYLDNKSMYFKVDHYEFYIVYETGSTKPMGFFSKDLVS 200
Query: 184 YHQNNLACILVFPPYQRRRLGTLLIEFSYTLSRCQGLISGPEVPLSPFGLIGYLKFWSFS 243
Y QNNLACIL+FPPYQRR LG LLIEFSY LS+ +G+ISGPEVPLSPFGLIGYLK+WS
Sbjct: 201 YQQNNLACILIFPPYQRRGLGLLLIEFSYKLSQLEGVISGPEVPLSPFGLIGYLKYWSQI 260
Query: 244 IVWQLTEGNLKDVAQVTLKDLSEATGFRINDIIQALKYLDCLSD-SEIRLNIIRSWARRN 302
+ W L EG+L +VTL+DLS TG R+ND+I LK+L+C+ + ++I L + SW + +
Sbjct: 261 LCWHLIEGDLAHYDKVTLEDLSIVTGMRVNDVILTLKHLNCIGENNQIYLQSLNSWLKLH 320
Query: 303 KVSHG-FMIKDEYLLLDD 319
F +KDEYLL+DD
Sbjct: 321 GTKRNWFKLKDEYLLIDD 338
>Hs14149875 [B] KOG2747 Histone acetyltransferase (MYST family)
Length = 458
Score = 160 bits (404), Expect = 3e-39
Identities = 91/236 (38%), Positives = 132/236 (55%), Gaps = 19/236 (8%)
Query: 83 LYVCEYCFKYTDDEAELIAHECFCRYKNKPPGRIKYRSPEYTIRRVKGSKHEVFCQCLCL 142
L++CEYC KY E H C+++ +PPG+ YR ++ V G H+++CQ LCL
Sbjct: 207 LWLCEYCLKYMKYEKSYRFHLGQCQWR-QPPGKEIYRKSNISVHEVDGKDHKIYCQNLCL 265
Query: 143 FTKLFLDNKSVYFKVKHFEFYIVYE--NNSTVPMAFFSKDLYSYHQNNLACILVFPPYQR 200
KLFLD+K++YF V+ F FYI+ E + +FSK+ S NN+ACIL PPYQR
Sbjct: 266 LAKLFLDHKTLYFDVEPFVFYILTEVDRQGAHIVGYFSKEKESPDGNNVACILTLPPYQR 325
Query: 201 RRLGTLLIEFSYTLSRCQGLISGPEVPLSPFGLIGYLKFWSFSIVWQLTEGNLKDV-AQV 259
R G LI FSY LS+ + + PE PLS G + Y +WS W L E NL+D +
Sbjct: 326 RGYGKFLIAFSYELSKLESTVGSPEKPLSDLGKLSYRSYWS----WVLLE-NLRDFRGTL 380
Query: 260 TLKDLSEATGFRINDIIQALKYLDCLSDSEIRLNIIRSWARRNKVSHGFMIKDEYL 315
++KDLS+ T NDII L+ LN+++ W ++ + + +E+L
Sbjct: 381 SIKDLSQMTSITQNDIISTLQ----------SLNMVKYWKGQHVICVTPKLVEEHL 426
>7290646 [B] KOG2747 Histone acetyltransferase (MYST family)
Length = 827
Score = 157 bits (396), Expect = 3e-38
Identities = 87/225 (38%), Positives = 127/225 (55%), Gaps = 15/225 (6%)
Query: 82 TLYVCEYCFKYTDDEAELIAHECFCRYKNKPPGRIKYRSPEYTIRRVKGSKHEVFCQCLC 141
TLYVCEYC KY + H C + +PPGR YR +I V G + ++CQ LC
Sbjct: 570 TLYVCEYCLKYMRFRSSYAYHLHECD-RRRPPGREIYRKGNISIYEVNGKEESLYCQLLC 628
Query: 142 LFTKLFLDNKSVYFKVKHFEFYIVYENNSTVP--MAFFSKDLYSYHQNNLACILVFPPYQ 199
L KLFLD+K +YF + F FYI+ E + + +FSK+ S N+ACILV PP+Q
Sbjct: 629 LMAKLFLDHKVLYFDMDPFLFYILCETDKEGSHIVGYFSKEKKSLENYNVACILVLPPHQ 688
Query: 200 RRRLGTLLIEFSYTLSRCQGLISGPEVPLSPFGLIGYLKFWSFSIVWQLTEGNLKDVAQV 259
R+ G LLI FSY LSR +G+I PE PLS G + Y +W+++++ + + Q+
Sbjct: 689 RKGFGKLLIAFSYELSRKEGVIGSPEKPLSDLGRLSYRSYWAYTLLELMKTRCAPE--QI 746
Query: 260 TLKDLSEATGFRINDIIQALKYLDCLSDSEIRLNIIRSWARRNKV 304
T+K+LSE +G +DII L+ + +I+ W +N +
Sbjct: 747 TIKELSEMSGITHDDIIYTLQ----------SMKMIKYWKGQNVI 781
>7291743 [B] KOG2747 Histone acetyltransferase (MYST family)
Length = 2271
Score = 148 bits (373), Expect = 1e-35
Identities = 82/236 (34%), Positives = 139/236 (58%), Gaps = 15/236 (6%)
Query: 83 LYVCEYCFKYTDDEAELIAHECFCRYKNKPPGRIKYRSPEYTIRRVKGSKHEVFCQCLCL 142
L++CE+C KYT + L H+ C +K +PPG +R ++ V G+ ++++CQ LCL
Sbjct: 740 LFLCEFCLKYTKSRSVLDRHQNKCIWK-QPPGTEIFRQGNISVFEVDGNVNKIYCQNLCL 798
Query: 143 FTKLFLDNKSVYFKVKHFEFYIVYENNSTVP--MAFFSKDLYSYHQNNLACILVFPPYQR 200
K FLD+K++Y+ V+ F FYI+ +N+ + + +FSK+ + + N++CIL P YQR
Sbjct: 799 LAKFFLDHKTLYYDVEPFLFYILTKNDQSGCHLVGYFSKEKHCTQKYNVSCILTMPQYQR 858
Query: 201 RRLGTLLIEFSYTLSRCQGLISGPEVPLSPFGLIGYLKFWSFSIVWQLTEGNLKDVAQVT 260
+ G LI+FSY LSR +G + PE PLS G + Y +W ++ L + ++ ++T
Sbjct: 859 QGYGRFLIDFSYLLSREEGQLGTPEKPLSDLGRLSYFSYWKSVVLEYLYKH--RNYTKIT 916
Query: 261 LKDLSEATGFRINDIIQALKYLDCL----SDSEIR--LNIIRSW----ARRNKVSH 306
KD++ TG I+DI A + L+ + +D +IR +N+ W A NK+++
Sbjct: 917 FKDIAIKTGLAISDIALAFELLNFIKLRKNDGDIRYQINVKIEWKKVLAHHNKMAN 972
>CE21225 [B] KOG2747 Histone acetyltransferase (MYST family)
Length = 458
Score = 144 bits (362), Expect = 2e-34
Identities = 74/207 (35%), Positives = 121/207 (57%), Gaps = 4/207 (1%)
Query: 80 IDTLYVCEYCFKYTDDEAELIAHECFCRYKNKPPGRIKYRSPEYTIRRVKGSKHEVFCQC 139
+D +Y+CE+C KY + L H C + PPG Y + + + G K++ + Q
Sbjct: 198 LDCIYICEFCLKYLKSKTCLKRHMEKCAMCH-PPGNQIYSHDKLSFFEIDGRKNKSYAQN 256
Query: 140 LCLFTKLFLDNKSVYFKVKHFEFYIVYENNSTVP--MAFFSKDLYSYHQNNLACILVFPP 197
LCL KLFLD+K++Y+ F FY++ E + + +FSK+ S + N+ACILV PP
Sbjct: 257 LCLLAKLFLDHKTLYYDTDPFLFYVLTEEDEKGHHIVGYFSKEKESAEEYNVACILVLPP 316
Query: 198 YQRRRLGTLLIEFSYTLSRCQGLISGPEVPLSPFGLIGYLKFWSFSIVWQLTEGNLKDVA 257
+Q++ G+LLIEFSY LS+ + PE PLS GL+ Y +WS +I+ +L +
Sbjct: 317 FQKKGYGSLLIEFSYELSKIEQKTGSPEKPLSDLGLLSYRSYWSMAIMKELFAFKRRHPG 376
Query: 258 Q-VTLKDLSEATGFRINDIIQALKYLD 283
+ +T++D+S++T + D++ L+ LD
Sbjct: 377 EDITVQDISQSTSIKREDVVSTLQQLD 403
>Hs5901962 [B] KOG2747 Histone acetyltransferase (MYST family)
Length = 611
Score = 143 bits (361), Expect = 3e-34
Identities = 77/213 (36%), Positives = 123/213 (57%), Gaps = 6/213 (2%)
Query: 75 EDQYWIDTLYVCEYCFKYTDDEAELIAHECFCRYKNKPPGRIKYRSPEYTIRRVKGSKHE 134
E+ + LY+CE+C KY + L H C +K+ PPG YR ++ V G K++
Sbjct: 357 EEYARLGRLYMCEFCLKYMKSQTILRRHMAKCVWKH-PPGDEIYRKGSISVFEVDGKKNK 415
Query: 135 VFCQCLCLFTKLFLDNKSVYFKVKHFEFYIVYENNSTVP--MAFFSKDLYSYHQNNLACI 192
++CQ LCL KLFLD+K++Y+ V+ F FY++ E ++T + +FSK+ S+ N++CI
Sbjct: 416 IYCQNLCLLAKLFLDHKTLYYDVEPFLFYVMTEADNTGCHLIGYFSKEKNSFLNYNVSCI 475
Query: 193 LVFPPYQRRRLGTLLIEFSYTLSRCQGLISGPEVPLSPFGLIGYLKFWSFSIVWQLTEGN 252
L P Y R+ G +LI+FSY LS+ + + PE PLS GLI Y +W ++ L
Sbjct: 476 LTMPQYMRQGYGKMLIDFSYLLSKVEEKVGSPERPLSDLGLISYRSYWKEVLLRYLHNFQ 535
Query: 253 LKDVAQVTLKDLSEATGFRINDIIQALKYLDCL 285
K ++++K++S+ T DI+ L+ L L
Sbjct: 536 GK---EISIKEISQETAVNPVDIVSTLQALQML 565
>7301677 [B] KOG2747 Histone acetyltransferase (MYST family)
Length = 421
Score = 143 bits (360), Expect = 4e-34
Identities = 79/203 (38%), Positives = 116/203 (56%), Gaps = 6/203 (2%)
Query: 82 TLYVCEYCFKYTDDEAELIAHECFCRYKNKPPGRIKYRSPEYTIRRVKGSKHEVFCQCLC 141
T+YVCE+C KY H C+ K PPG + YR I V G K +++CQCLC
Sbjct: 173 TIYVCEFCLKYMCLRKSYSYHLYDCK-KRCPPGSLLYRKDNIYIYEVDGHKEQLYCQCLC 231
Query: 142 LFTKLFLDNKSVYFKVKHFEFYI--VYENNSTVPMAFFSKDLYSYHQNNLACILVFPPYQ 199
L +KLFL+NK + + F FYI + + + +F+++ + NL CILV PPY
Sbjct: 232 LMSKLFLENKKILYSSSSFLFYILCLKDKDGEHFAGYFARE-KTMLNINLNCILVLPPYM 290
Query: 200 RRRLGTLLIEFSYTLSRCQGLISGPEVPLSPFGLIGYLKFWSFSIVWQLTEGNLKDVAQV 259
R+ G LLI+ SY +SR + I GP+ PLS + YL +W ++ L + D+ V
Sbjct: 291 RKGYGKLLIDLSYEISRREACIGGPKKPLSKVARLCYLSYWGHILLNLLRHHSSPDL--V 348
Query: 260 TLKDLSEATGFRINDIIQALKYL 282
T+++LS+ATGFR DII L+++
Sbjct: 349 TIEELSKATGFREEDIISTLEFM 371
>7290469 [B] KOG2747 Histone acetyltransferase (MYST family)
Length = 510
Score = 142 bits (359), Expect = 5e-34
Identities = 77/209 (36%), Positives = 116/209 (54%), Gaps = 6/209 (2%)
Query: 83 LYVCEYCFKYTDDEAELIAHECFCRYKNKPPGRIKYRSPEYTIRRVKGSKHEVFCQCLCL 142
+Y+CE+C KY L H C ++ PPG YR + + G K++V+ Q LCL
Sbjct: 256 IYICEFCLKYRKSRKCLERHLSKCNLRH-PPGNEIYRKHTISFFEIDGRKNKVYAQNLCL 314
Query: 143 FTKLFLDNKSVYFKVKHFEFYIVYENNSTV--PMAFFSKDLYSYHQNNLACILVFPPYQR 200
KLFLD+K++Y+ F FY++ E +S + +FSK+ S N+ACIL PPYQR
Sbjct: 315 LAKLFLDHKTLYYDTDPFLFYVMTEFDSRGFHIVGYFSKEKESTEDYNVACILTMPPYQR 374
Query: 201 RRLGTLLIEFSYTLSRCQGLISGPEVPLSPFGLIGYLKFWSFSIVWQLTEGNLK---DVA 257
+ G LLIEFSY LS+ +G PE PLS GL+ Y +W+ +I+ N +
Sbjct: 375 KGYGKLLIEFSYELSKFEGKTGSPEKPLSDLGLLSYRSYWAQTILEIFISQNPSTDGEKP 434
Query: 258 QVTLKDLSEATGFRINDIIQALKYLDCLS 286
+T+ D+ E T + D+I L+ L+ ++
Sbjct: 435 TITINDICECTSIKKEDVISTLQNLNLIN 463
>Hs5803098 [B] KOG2747 Histone acetyltransferase (MYST family)
Length = 2004
Score = 142 bits (357), Expect = 8e-34
Identities = 86/251 (34%), Positives = 132/251 (52%), Gaps = 13/251 (5%)
Query: 63 HTAKQSPTEKKFEDQYWIDTLYVCEYCFKYTDDEAELIAHECFCRYKNKPPGRIKYRSPE 122
HT SP +++ + LY+CE+C KY L H C + + P I YR
Sbjct: 520 HTWYSSPYPQEYSR---LPKLYLCEFCLKYMKSRTILQQHMKKCGWFHPPANEI-YRKNN 575
Query: 123 YTIRRVKGSKHEVFCQCLCLFTKLFLDNKSVYFKVKHFEFYIVYENN--STVPMAFFSKD 180
++ V G+ ++CQ LCL KLFLD+K++Y+ V+ F FY++ +N+ + +FSK+
Sbjct: 576 ISVFEVDGNVSTIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTQNDVKGCHLVGYFSKE 635
Query: 181 LYSYHQNNLACILVFPPYQRRRLGTLLIEFSYTLSRCQGLISGPEVPLSPFGLIGYLKFW 240
+ + N++CI++ P YQR+ G LI+FSY LS+ +G PE PLS G + Y+ +W
Sbjct: 636 KHCQQKYNVSCIMILPQYQRKGYGRFLIDFSYLLSKREGQAGSPEKPLSDLGRLSYMAYW 695
Query: 241 SFSIVWQLTEGNLKDVAQVTLKDLSEATGFRINDIIQALKYLDCLSDSEIRLNIIRSWAR 300
I+ L N K Q+++K LS+ TG DI L +L L + II R
Sbjct: 696 KSVILECLYHQNDK---QISIKKLSKLTGICPQDITSTLHHLRMLDFRSDQFVII----R 748
Query: 301 RNKVSHGFMIK 311
R K+ M K
Sbjct: 749 REKLIQDHMAK 759
>Hs6912512 [B] KOG2747 Histone acetyltransferase (MYST family)
Length = 2073
Score = 140 bits (353), Expect = 2e-33
Identities = 79/237 (33%), Positives = 129/237 (54%), Gaps = 17/237 (7%)
Query: 73 KFEDQYWIDT-----------LYVCEYCFKYTDDEAELIAHECFCRYKNKPPGRIKYRSP 121
K+E Q W + LY+CE+C KY + L+ H C + + P I YR
Sbjct: 727 KYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANEI-YRRK 785
Query: 122 EYTIRRVKGSKHEVFCQCLCLFTKLFLDNKSVYFKVKHFEFYIVYENNSTVP--MAFFSK 179
+ ++ V G+ +++CQ LCL KLFLD+K++Y+ V+ F FY++ +N+ + + SK
Sbjct: 786 DLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTKNDEKGCHLVGYLSK 845
Query: 180 DLYSYHQNNLACILVFPPYQRRRLGTLLIEFSYTLSRCQGLISGPEVPLSPFGLIGYLKF 239
+ + N++CI++ P +QR+ G LI+FSY LSR +G PE PLS G + YL +
Sbjct: 846 EKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSYLLSRREGQAGSPEKPLSDLGRLSYLAY 905
Query: 240 WSFSIVWQLTEGNLKDVAQVTLKDLSEATGFRINDIIQALKYLDCLSDSEIRLNIIR 296
W I+ L + + +++K +S ATG +DI L++L + + R IIR
Sbjct: 906 WKSVILEYLYHHHER---HISIKAISRATGMCPHDIATTLQHLHMIDKRDGRFVIIR 959
>Hs5454128 [B] KOG2747 Histone acetyltransferase (MYST family)
Length = 513
Score = 140 bits (353), Expect = 2e-33
Identities = 78/211 (36%), Positives = 117/211 (54%), Gaps = 5/211 (2%)
Query: 80 IDTLYVCEYCFKYTDDEAELIAHECFCRYKNKPPGRIKYRSPEYTIRRVKGSKHEVFCQC 139
+ LY+CE+C KY L H C ++ PPG YR + + G K++ + Q
Sbjct: 257 LPVLYLCEFCLKYGRSLKCLQRHLTKCDLRH-PPGNEIYRKGTISFFEIDGRKNKSYSQN 315
Query: 140 LCLFTKLFLDNKSVYFKVKHFEFYIV--YENNSTVPMAFFSKDLYSYHQNNLACILVFPP 197
LCL K FLD+K++Y+ F FY++ Y+ + +FSK+ S N+ACIL PP
Sbjct: 316 LCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHIVGYFSKEKESTEDYNVACILTLPP 375
Query: 198 YQRRRLGTLLIEFSYTLSRCQGLISGPEVPLSPFGLIGYLKFWSFSIVWQL--TEGNLKD 255
YQRR LLIEFSY LS+ +G PE PLS GL+ Y +WS +I+ L + +
Sbjct: 376 YQRRGYRKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSYRSYWSQTILEILMGLKSESGE 435
Query: 256 VAQVTLKDLSEATGFRINDIIQALKYLDCLS 286
Q+T+ ++SE T + D+I L+YL+ ++
Sbjct: 436 RPQITINEISEITSIKKEDVISTLQYLNLIN 466
>At5g64610 [B] KOG2747 Histone acetyltransferase (MYST family)
Length = 445
Score = 139 bits (350), Expect = 5e-33
Identities = 77/205 (37%), Positives = 117/205 (56%), Gaps = 7/205 (3%)
Query: 83 LYVCEYCFKYTDDEAELIAHECFCRYKNKPPGRIKYRSPEYTIRRVKGSKHEVFCQCLCL 142
L+ CE+C + + +L H C K+ PPG YRS ++ V G K++V+ Q LC
Sbjct: 202 LFFCEFCLSFMKRKEQLQRHMRKCDLKH-PPGDEIYRSSTLSMFEVDGKKNKVYAQNLCY 260
Query: 143 FTKLFLDNKSVYFKVKHFEFYIVYE--NNSTVPMAFFSKDLYSYHQNNLACILVFPPYQR 200
KLFLD+K++Y+ V F FYI+ E + + +FSK+ +S NLACIL PPYQR
Sbjct: 261 LAKLFLDHKTLYYDVDLFLFYILCECDDRGCHMVGYFSKEKHSEEAYNLACILTLPPYQR 320
Query: 201 RRLGTLLIEFSYTLSRCQGLISGPEVPLSPFGLIGYLKFWSFSIVWQLTEGNLKDVAQVT 260
+ G LI FSY LS+ +G + PE PLS GL+ Y +W+ ++ L K ++
Sbjct: 321 KGYGKFLIAFSYELSKKEGKVGTPERPLSDLGLVSYRGYWTRILLDILK----KHKGNIS 376
Query: 261 LKDLSEATGFRINDIIQALKYLDCL 285
+K+LS+ T + DI+ L+ L+ +
Sbjct: 377 IKELSDMTAIKAEDILSTLQSLELI 401
>CE23850 [B] KOG2747 Histone acetyltransferase (MYST family)
Length = 550
Score = 139 bits (349), Expect = 7e-33
Identities = 79/218 (36%), Positives = 120/218 (54%), Gaps = 29/218 (13%)
Query: 83 LYVCEYCFKYTDDEAELIAHECFCRYKNKPPGRIKYRSPEYTIRRVKGSKHEVF------ 136
+Y+CEYC YT H C+ + +PPG YR ++ V GS ++F
Sbjct: 216 IYMCEYCLLYTPHHERFKQHIDTCKVR-QPPGNEIYRKDHLSVYEVDGSGQKLFQPFFAP 274
Query: 137 -----------CQCLCLFTKLFLDNKSVYFKVKHFEFYIVYENNSTVP--MAFFSKDLYS 183
CQCLCL +KLF+D+K++YF V F FY++ E + + +FS+++ S
Sbjct: 275 FPPKLPIFQLYCQCLCLLSKLFMDHKTLYFDVDDFMFYVLCETDEHGAHIVGYFSREVES 334
Query: 184 YHQNNLACILVFPPYQRRRLGTLLIEFSYTLSRCQGLISGPEVPLSPFGLIGYLKFWSFS 243
NNLACI+VFPP+Q++ G LLI+FSY LSR +G I PE PLS G + Y +W +
Sbjct: 335 --ANNLACIMVFPPFQKKGYGKLLIQFSYELSRREGYIGMPEKPLSDLGKVSYRSYWWWR 392
Query: 244 I--VWQLTEGNLKDVAQVTLKDLSEATGFRINDIIQAL 279
+ ++ + +G+ VT LS +G ++DI+ L
Sbjct: 393 LMKLFHIHQGH-----TVTATFLSNESGIAVDDIVSTL 425
>At5g09740 [B] KOG2747 Histone acetyltransferase (MYST family)
Length = 445
Score = 135 bits (341), Expect = 6e-32
Identities = 75/205 (36%), Positives = 116/205 (56%), Gaps = 7/205 (3%)
Query: 83 LYVCEYCFKYTDDEAELIAHECFCRYKNKPPGRIKYRSPEYTIRRVKGSKHEVFCQCLCL 142
L+ CE+C + + +L H C K+ PPG YRS ++ V G K++V+ Q LC
Sbjct: 202 LFFCEFCLNFMKRKEQLQRHMRKCDLKH-PPGDEIYRSGTLSMFEVDGKKNKVYAQNLCY 260
Query: 143 FTKLFLDNKSVYFKVKHFEFYIVYE--NNSTVPMAFFSKDLYSYHQNNLACILVFPPYQR 200
KLFLD+K++Y+ V F FY++ E + + +FSK+ +S NLACIL P YQR
Sbjct: 261 LAKLFLDHKTLYYDVDLFLFYVLCECDDRGCHMVGYFSKEKHSEEAYNLACILTLPSYQR 320
Query: 201 RRLGTLLIEFSYTLSRCQGLISGPEVPLSPFGLIGYLKFWSFSIVWQLTEGNLKDVAQVT 260
+ G LI FSY LS+ +G + PE PLS GL+ Y +W+ ++ L K ++
Sbjct: 321 KGYGKFLIAFSYELSKKEGKVGTPERPLSDLGLLSYRGYWTRVLLEILK----KHKGNIS 376
Query: 261 LKDLSEATGFRINDIIQALKYLDCL 285
+K+LS+ T + DI+ L+ L+ +
Sbjct: 377 IKELSDVTAIKAEDILSTLQSLELI 401
>SPAC17G8.13c [B] KOG2747 Histone acetyltransferase (MYST family)
Length = 407
Score = 134 bits (338), Expect = 1e-31
Identities = 69/202 (34%), Positives = 112/202 (55%), Gaps = 7/202 (3%)
Query: 83 LYVCEYCFKYTDDEAELIAHECFCRYKNKPPGRIKYRSPEYTIRRVKGSKHEVFCQCLCL 142
LY+CE C KY + + L H+ C + + PPG YR +I V G + ++CQ LCL
Sbjct: 131 LYICESCLKYMNSDHVLQRHKMKCSW-SYPPGDEIYRDKNISIFEVDGQRQPIYCQNLCL 189
Query: 143 FTKLFLDNKSVYFKVKHFEFYIV--YENNSTVPMAFFSKDLYSYHQNNLACILVFPPYQR 200
K+FL +K +Y+ V+ F FY++ ++ + +FSK+ S N++CIL P YQR
Sbjct: 190 LAKMFLHSKMLYYDVEPFLFYVLTEFDGQECKVIGYFSKEKRSASDYNVSCILTLPIYQR 249
Query: 201 RRLGTLLIEFSYTLSRCQGLISGPEVPLSPFGLIGYLKFWSFSIVWQLTEGNLKDVAQVT 260
R G LI+FSY L++ +G + PE PLS GL+ Y +W + L L+ ++
Sbjct: 250 RGYGVFLIDFSYLLTQVEGKLGSPEKPLSDLGLVTYRSYWKMRVAKAL----LEITTPIS 305
Query: 261 LKDLSEATGFRINDIIQALKYL 282
+ ++++T +D+I L+ L
Sbjct: 306 INAIAKSTSMVCDDVISTLESL 327
>SPAC637.12c [B] KOG2747 Histone acetyltransferase (MYST family)
Length = 463
Score = 132 bits (332), Expect = 7e-31
Identities = 77/220 (35%), Positives = 115/220 (52%), Gaps = 10/220 (4%)
Query: 68 SPTEKKFEDQYWIDTLYVCEYCFKYTDDEAELIAHECFCRYKNKPPGRIKYRSPEYTIRR 127
SP K+F + +D +Y+C +CF Y E + H C ++ PPG YR +
Sbjct: 200 SPYPKEFSE---VDIVYICSFCFCYYGSERQFQRHREKCTLQH-PPGNEIYRDDYISFFE 255
Query: 128 VKGSKHEVFCQCLCLFTKLFLDNKSVYFKVKHFEFYIVYENNS--TVPMAFFSKDLYSYH 185
+ G K +C+ +CL +KLFLD+K +Y+ V F FY + + + +FSK+ S
Sbjct: 256 IDGRKQRTWCRNICLLSKLFLDHKMLYYDVDPFLFYCMCRRDEYGCHLVGYFSKEKESSE 315
Query: 186 QNNLACILVFPPYQRRRLGTLLIEFSYTLSRCQGLISGPEVPLSPFGLIGYLKFWSFSIV 245
NLACIL P YQR G LLI+FSY L++ + PE PLS GLI Y +W+ I+
Sbjct: 316 NYNLACILTLPQYQRHGYGKLLIQFSYELTKREHKHGSPEKPLSDLGLISYRAYWAEQII 375
Query: 246 WQLTEGNLKDVAQVTLKDLSEATGFRINDIIQALKYLDCL 285
L G + T+ +L+ T ND++ L+ L+ L
Sbjct: 376 -NLVLGMR---TETTIDELANKTSMTTNDVLHTLQALNML 411
>YBL052c [B] KOG2747 Histone acetyltransferase (MYST family)
Length = 831
Score = 130 bits (328), Expect = 2e-30
Identities = 87/312 (27%), Positives = 139/312 (43%), Gaps = 59/312 (18%)
Query: 26 IRHVQFGLNKRFATWYGSNVYFGRNKRTLGFKESNNEHTAKQSPTEKKFEDQYWIDTL-- 83
I+ + F N + AT+ NV + T + NE K+ + +++ W +
Sbjct: 219 IKFLTFLENSKSATYINGNVSLCNHNET----DQENEDRKKRKGKVPRIKNKVWFSQIEY 274
Query: 84 --------------------------YVCEYCFKYTDDEAELIAHECFCRYKNKPPGRIK 117
++CE+C KY H+ C KPPG
Sbjct: 275 IVLRNYEIKPWYTSPFPEHINQNKMVFICEFCLKYMTSRYTFYRHQLKC-LTFKPPGNEI 333
Query: 118 YRSPEYTIRRVKGSKHEVFCQCLCLFTKLFLDNKSVYFKVKHFEFYIVYENNSTVP---- 173
YR + ++ + G ++ ++CQ LCL K F+++K++Y+ V+ F FYI+ E T
Sbjct: 334 YRDGKLSVWEIDGRENVLYCQNLCLLAKCFINSKTLYYDVEPFIFYILTEREDTENHPYQ 393
Query: 174 -------MAFFSKDLYSYHQNNLACILVFPPYQRRRLGTLLIEFSYTLSRCQGLISGPEV 226
+ +FSK+ ++ + NL+CIL P YQR+ G L+EFSY LSR + PE
Sbjct: 394 NAAKFHFVGYFSKEKFNSNDYNLSCILTLPIYQRKGYGQFLMEFSYLLSRKESKFGTPEK 453
Query: 227 PLSPFGLIGYLKFWSFSIVWQLTEGNLKDVA-------------QVTLKDLSEATGFRIN 273
PLS GL+ Y FW L + L+D A QV+L D+++ TG
Sbjct: 454 PLSDLGLLTYRTFWKIKCAEVLLK--LRDSARRRSNNKNEDTFQQVSLNDIAKLTGMIPT 511
Query: 274 DIIQALKYLDCL 285
D++ L+ L L
Sbjct: 512 DVVFGLEQLQVL 523
>ECU10g0660 [B] KOG2747 Histone acetyltransferase (MYST family)
Length = 377
Score = 129 bits (325), Expect = 4e-30
Identities = 73/201 (36%), Positives = 113/201 (55%), Gaps = 8/201 (3%)
Query: 81 DTLYVCEYCFKYTDDEAELIAHECFCRYKNKPPGRIKYRSPEYTIRRVKGSKHEVFCQCL 140
D +Y+CE+C Y L+ H C+ ++ PPGR YR + G + +C+ L
Sbjct: 142 DIVYICEFCLYYFSAVDSLVLHARQCKLRH-PPGREIYRDGVLSFFECDGHIQKNYCRNL 200
Query: 141 CLFTKLFLDNKSVYFKVKHFEFYIV--YENNSTVPMAFFSKDLYSYHQNNLACILVFPPY 198
L +KLFLD+KS+Y+ + F FY++ E+N + +FSK+ S NLACIL P
Sbjct: 201 SLLSKLFLDHKSLYYDIDVFMFYVLCRLEDNGYQIVGYFSKEKMSEQGYNLACILTLPFE 260
Query: 199 QRRRLGTLLIEFSYTLSRCQGLISGPEVPLSPFGLIGYLKFWSFSIVWQLTEGNLKDVAQ 258
QR+ G +LI+FSY LSR + ++SGPE PLS GL+ Y +W IV L++ + +
Sbjct: 261 QRKGYGKILIDFSYLLSRRENVVSGPEKPLSDLGLLSYRAYWMEVIVEYLSKHD-----K 315
Query: 259 VTLKDLSEATGFRINDIIQAL 279
++ ++S T +D+I L
Sbjct: 316 ASISEISRETYISEDDVIGTL 336
>Hs20549811 [B] KOG2747 Histone acetyltransferase (MYST family)
Length = 194
Score = 128 bits (321), Expect = 1e-29
Identities = 65/168 (38%), Positives = 100/168 (58%), Gaps = 3/168 (1%)
Query: 75 EDQYWIDTLYVCEYCFKYTDDEAELIAHECFCRYKNKPPGRIKYRSPEYTIRRVKGSKHE 134
E+ + LY+CE+C KY + L H C +K+ P G YR ++ V G K++
Sbjct: 22 EEYARLGRLYMCEFCLKYMKSQMILRQHMAKCVWKH-PLGDEIYRKGSVSVFEVDGKKNK 80
Query: 135 VFCQCLCLFTKLFLDNKSVYFKVKHFEFYIVYENNSTVP--MAFFSKDLYSYHQNNLACI 192
++CQ LCL KLFLD+K++Y+ V+ F FY++ E ++T + +FSK+ S+ N++CI
Sbjct: 81 IYCQNLCLLAKLFLDHKTLYYDVEPFLFYVMTEADNTGCHLIGYFSKEKNSFLNYNVSCI 140
Query: 193 LVFPPYQRRRLGTLLIEFSYTLSRCQGLISGPEVPLSPFGLIGYLKFW 240
L P Y R+ G +LI+FSY LS+ + + PE PLS GLI +W
Sbjct: 141 LTMPQYMRQGYGKMLIDFSYLLSKVEEKVGSPECPLSDLGLISCCSYW 188
>YOR244w [B] KOG2747 Histone acetyltransferase (MYST family)
Length = 445
Score = 126 bits (316), Expect = 5e-29
Identities = 80/250 (32%), Positives = 121/250 (48%), Gaps = 20/250 (8%)
Query: 52 RTLGFKESNNEHTAKQSPTEKKFEDQYWIDTLYVCEYCFKYTDDEAELI---------AH 102
RT G N A+ + +Y I+ Y Y + TD++ I +
Sbjct: 149 RTSGSMTQNPHEVARVRNLNRIIMGKYEIEPWYFSPYPIELTDEDFIYIDDFTLQYFGSK 208
Query: 103 ECFCRYKNK-----PPGRIKYRSPEYTIRRVKGSKHEVFCQCLCLFTKLFLDNKSVYFKV 157
+ + RY+ K PPG YR + + G K +C+ LCL +KLFLD+K++Y+ V
Sbjct: 209 KQYERYRKKCTLRHPPGNEIYRDDYVSFFEIDGRKQRTWCRNLCLLSKLFLDHKTLYYDV 268
Query: 158 KHFEFYIVYENNSTVP--MAFFSKDLYSYHQNNLACILVFPPYQRRRLGTLLIEFSYTLS 215
F FY + + + +FSK+ S N+ACIL P YQR G LLIEFSY LS
Sbjct: 269 DPFLFYCMTRRDELGHHLVGYFSKEKESADGYNVACILTLPQYQRMGYGKLLIEFSYELS 328
Query: 216 RCQGLISGPEVPLSPFGLIGYLKFWSFSIVWQLTEGNLKDVAQVTLKDLSEATGFRINDI 275
+ + + PE PLS GL+ Y +WS +++ L E ++T+ ++S T DI
Sbjct: 329 KKENKVGSPEKPLSDLGLLSYRAYWSDTLITLLVEHQ----KEITIDEISSMTSMTTTDI 384
Query: 276 IQALKYLDCL 285
+ K L+ L
Sbjct: 385 LHTAKTLNIL 394
>CE27818 [B] KOG2747 Histone acetyltransferase (MYST family)
Length = 617
Score = 125 bits (315), Expect = 6e-29
Identities = 72/199 (36%), Positives = 111/199 (55%), Gaps = 5/199 (2%)
Query: 83 LYVCEYCFKYTDDEAELIAHECFCRYKNKPPGRIKYRSPEYTIRRVKGSKHEVFCQCLCL 142
LY C++C T+ + +LI H C K+ PPG YR+ V G+ + +CQ LCL
Sbjct: 363 LYACKFCLHTTNLKEDLIVHWDICNAKH-PPGTEIYRNDGLAFFEVDGAVQKKYCQDLCL 421
Query: 143 FTKLFLDNKSVYFKVKHFEFYIVYE--NNSTVPMAFFSKDLYSYHQNNLACILVFPPYQR 200
+KLF+ +K++Y +V+ F+FY++ E V + +FSK+ NNL+C+LV P Q+
Sbjct: 422 ISKLFIASKTLYDEVETFKFYVLCEITTEGYVIVGYFSKEKNPSKNNNLSCLLVLPMVQK 481
Query: 201 RRLGTLLIEFSYTLSRCQGLISGPEVPLSPFGLIGYLKFWSFSIVWQLTEGNLKDVAQVT 260
G LLI+ SY LSR + I PE PLS G++ Y +W S++ + E D ++
Sbjct: 482 MGYGRLLIDMSYELSRLEMRIGHPEHPLSDLGILAYRGYWRSSLLCYIREHRNYD--RLN 539
Query: 261 LKDLSEATGFRINDIIQAL 279
+KD+ AT DI+ L
Sbjct: 540 IKDMCLATRIAPVDIVNQL 558
>CE06262 [B] KOG2747 Histone acetyltransferase (MYST family)
Length = 1271
Score = 124 bits (311), Expect = 2e-28
Identities = 71/206 (34%), Positives = 112/206 (53%), Gaps = 9/206 (4%)
Query: 80 IDTLYVCEYCFKYTDDEAELIAHECFCRYKNKPPGRIKYRSPEYTIRRVKGSKHEVFCQC 139
+ L++CE+CF Y + + H C + PPG YR + ++ V G + +CQ
Sbjct: 260 VKKLFICEFCFFYARSDEIMQNHAKKCMLR-APPGLEIYRKGDISVFEVDGRLQKEYCQT 318
Query: 140 LCLFTKLFLDNKSVYFKVKHFEFYIVYENNSTVP--MAFFSKDLYSYHQNNLACILVFPP 197
LCL +++FL++K+V++ + F FYIV N+ +FSK+ Y NNL+CI+ P
Sbjct: 319 LCLVSRMFLESKTVFYDTEPFFFYIVTINDDIGCHFAGYFSKEKYEPDVNNLSCIMTLPC 378
Query: 198 YQRRRLGTLLIEFSYTLSRCQGLISGPEVPLSPFGLIGYLKFWSFSIVWQLTEGNLKDVA 257
YQ LG LI+ SY LSR + GPE PLS G Y +W +I L G LKD
Sbjct: 379 YQEMGLGRFLIDISYALSRKEKWFGGPEQPLSELGRKAYGGYWRTTIASCL--GRLKDEL 436
Query: 258 Q----VTLKDLSEATGFRINDIIQAL 279
+ +++K +++ TG +DI++ +
Sbjct: 437 EFGSGISIKMIADDTGVNCHDILEVV 462
>7297249 [B] KOG2747 Histone acetyltransferase (MYST family)
Length = 769
Score = 95.1 bits (235), Expect = 1e-19
Identities = 55/162 (33%), Positives = 92/162 (55%), Gaps = 9/162 (5%)
Query: 75 EDQYWIDTLYVCEYCFKYTDDEAELIAHECFCRYKNKPPGRIKYRSPEYTIRRVKGSKHE 134
+D + +Y+CE+C +Y E + H C +++ PPG YR + + +V G +++
Sbjct: 548 DDAARLPKMYICEFCLRYQKSETGIKRHAEKCVWRH-PPGDEIYRKGKLQVWQVDGKRYK 606
Query: 135 VFCQCLCLFTKLFLDNKSVYFKVKHFEFYI--VYENNSTVPMAFFSKDLYSYHQN----N 188
+CQ LCL K FLD+K++Y+ V+ F FYI + + + + +FSK + + N
Sbjct: 607 QYCQHLCLLAKFFLDHKTLYYDVEPFLFYIMTLADVDGCHIVGYFSKHIPFLQEKNSFYN 666
Query: 189 LACILVFPPYQRRRLGTLLIEF-SYTLSRCQGLISGPE-VPL 228
++CIL PPYQR+ G LLI+F ++ + SGP+ VPL
Sbjct: 667 VSCILTLPPYQRKGYGRLLIDFRKNRIAGETSIRSGPDLVPL 708
>ECU09g1310 [B] KOG2747 Histone acetyltransferase (MYST family)
Length = 288
Score = 84.0 bits (206), Expect = 3e-16
Identities = 59/223 (26%), Positives = 104/223 (46%), Gaps = 19/223 (8%)
Query: 74 FEDQYWI----DTLYVCEYCFKYTDDEAELIAHECFCRYKNKPPGRIKYRSPE--YTIRR 127
F ++ W+ + +Y+C+ C D L H C PGR Y + ++
Sbjct: 58 FRNRVWLFSDKNVVYICDRCLHQYWDSTSLGRHRKEC--SQGIPGRHVYTDKDEGISVIE 115
Query: 128 VKGSKHEVFCQCLCLFTKLFLDNKSVYFKVKHFEFYIVYENNSTVPMAFFSKDLYSYHQN 187
+ G V C+ +C + F+ K+++ V + FY++ FFSK+ S ++
Sbjct: 116 IDGGCESVLCRRICTIGRAFIHRKTLHLDVDGYLFYVLLIGGRVA--GFFSKEKES-EKH 172
Query: 188 NLACILVFPPYQRRRLGTLLIEFSYTLSRCQGLISGPEVPLSPFGLIGYLKFWSFSIVWQ 247
NL+C+LV PP++ R G+L+I+ SY L PE PLS G Y ++W ++
Sbjct: 173 NLSCLLVLPPHRSRGYGSLMIDLSYILGP-----GTPEKPLSKEGRAVYKRYWRNMVLKT 227
Query: 248 LTEGNLKDVAQVTLKDLSEATGFRINDIIQALKYLDCLSDSEI 290
L + ++++ +S +G I+D I L+ L +S I
Sbjct: 228 LRK---MGGEEMSICSISAESGLSIDDTIHGLELLGINPESHI 267
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.323 0.140 0.440
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,606,717
Number of Sequences: 60738
Number of extensions: 972007
Number of successful extensions: 2223
Number of sequences better than 1.0e-05: 24
Number of HSP's better than 0.0 without gapping: 23
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 2141
Number of HSP's gapped (non-prelim): 24
length of query: 319
length of database: 30,389,216
effective HSP length: 106
effective length of query: 213
effective length of database: 23,950,988
effective search space: 5101560444
effective search space used: 5101560444
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)