ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI4655 good F KOG2555 Nucleotide transport and metabolism AICAR transformylase/IMP cyclohydrolase/methylglyoxal synthase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI4655 1619715 1621484 590
(590 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YMR120c [F] KOG2555 AICAR transformylase/IMP cyclohydrolase/meth... 1030 0.0
YLR028c [F] KOG2555 AICAR transformylase/IMP cyclohydrolase/meth... 987 0.0
SPCPB16A4.03c [F] KOG2555 AICAR transformylase/IMP cyclohydrolas... 835 0.0
Hs20127454 [F] KOG2555 AICAR transformylase/IMP cyclohydrolase/m... 703 0.0
7301227 [F] KOG2555 AICAR transformylase/IMP cyclohydrolase/meth... 703 0.0
CE26363 [F] KOG2555 AICAR transformylase/IMP cyclohydrolase/meth... 437 e-122
At2g35040 [F] KOG2555 AICAR transformylase/IMP cyclohydrolase/me... 229 7e-60
CE04899 [F] KOG2555 AICAR transformylase/IMP cyclohydrolase/meth... 193 5e-49
Hs20468150 [F] KOG2555 AICAR transformylase/IMP cyclohydrolase/m... 77 7e-14
>YMR120c [F] KOG2555 AICAR transformylase/IMP cyclohydrolase/methylglyoxal
synthase
Length = 592
Score = 1030 bits (2663), Expect = 0.0
Identities = 508/589 (86%), Positives = 547/589 (92%), Gaps = 1/589 (0%)
Query: 3 HTKTAILSVYDKTGLLDLAKGLAENNVRILASGGTAKMVREAGFPVDDVSSITHAPEMLG 62
+TKTAILSVYDKTGLLDLA+GL E NVRILASGGTA+M+R+AGFP++DVS+ITHAPEMLG
Sbjct: 4 YTKTAILSVYDKTGLLDLARGLIEKNVRILASGGTARMIRDAGFPIEDVSAITHAPEMLG 63
Query: 63 GRVKTLHPAVHGGILARNLESDEKDLKEQNIDKVDFVVCNLYPFKETVAKVGVSIPEAVE 122
GRVKTLHPAVHGGILAR+++SDEKDLKEQ+I+KVD+VVCNLYPFKETVAKVGV+IPEAVE
Sbjct: 64 GRVKTLHPAVHGGILARDIDSDEKDLKEQHIEKVDYVVCNLYPFKETVAKVGVTIPEAVE 123
Query: 123 EIDIGGVTLLRAAAKNHARVTILSDPKDYPQFLNELQK-GEISSDLRNTLALKAFEHTAD 181
EIDIGGVTLLRAAAKNHARVTILSDPKDY +FL+EL GEIS DLRN LALKAFEHTAD
Sbjct: 124 EIDIGGVTLLRAAAKNHARVTILSDPKDYSEFLSELSSNGEISQDLRNRLALKAFEHTAD 183
Query: 182 YDTAISDFFRKQYSENKTQLALRYGANPHQKPAQAFVTQQEELPFKVLSGSPGYINLLDA 241
YD AISDFFRKQYSE + Q+ LRYGANPHQKPAQA+V+QQ+ LPFKVL GSPGYINLLDA
Sbjct: 184 YDAAISDFFRKQYSEGQAQITLRYGANPHQKPAQAYVSQQDSLPFKVLCGSPGYINLLDA 243
Query: 242 LNSWPLVKEXXXXXXXXXXXXFKHVSPAGAAVGLPLSDVEKQIYFVADIENLSPLACAYA 301
LNSWPLVKE FKHVSPAGAAVG+PLSDVEKQ+YFVADIENLSPLACAYA
Sbjct: 244 LNSWPLVKELSASLNLPAAASFKHVSPAGAAVGIPLSDVEKQVYFVADIENLSPLACAYA 303
Query: 302 RARGADRMSSFGDWIALSNIVDVPTAKIISREVSDGVIAPGFEPEALEILKKKKNGKYCI 361
RARGADRMSSFGDWIALSNIVDVPTAKIISREVSDGVIAPG+EPEAL IL KKK GKYCI
Sbjct: 304 RARGADRMSSFGDWIALSNIVDVPTAKIISREVSDGVIAPGYEPEALAILSKKKGGKYCI 363
Query: 362 LQIDPNYTPEALESRQVYGVTLQQKRNDAIINKSSFKEIVSQNKDLPEQAVIDLTVATIA 421
LQIDPNY PEA+E RQVYGVTL+QKRNDAIIN+S+FKEIVSQNK+L EQA+IDLTVATIA
Sbjct: 364 LQIDPNYVPEAVERRQVYGVTLEQKRNDAIINQSTFKEIVSQNKNLTEQAIIDLTVATIA 423
Query: 422 LKYTQSNSVCYAKNGMVVGLGAGQQSRIHCTRLAGDKADNWWLRQHPRVLGFKWAKGVKR 481
+KYTQSNSVCYA+NGMVVGLGAGQQSRIHCTRLAGDKADNWW RQHPRVL KWAKGVKR
Sbjct: 424 IKYTQSNSVCYARNGMVVGLGAGQQSRIHCTRLAGDKADNWWFRQHPRVLEIKWAKGVKR 483
Query: 482 PEKSNAIDLFVTGQIPTEEPEKSEYESKFETIPEPLTAEEKKSWMSKLTNVALSSDAFFP 541
PEKSNAIDLFVTGQIPTEEPE SEY+SKFE IP+P T EE+K W+SKLTNV+LSSDAFFP
Sbjct: 484 PEKSNAIDLFVTGQIPTEEPELSEYQSKFEEIPKPFTPEERKEWLSKLTNVSLSSDAFFP 543
Query: 542 FPDNVYRAVRSGVKYIAAPSGSVMDKAVFGAADSFDLVYVENPIRLFHH 590
FPDNVYRAV+SGVKYIAAPSGSVMDK VF AADSFDLVYVENPIRLFHH
Sbjct: 544 FPDNVYRAVKSGVKYIAAPSGSVMDKVVFSAADSFDLVYVENPIRLFHH 592
>YLR028c [F] KOG2555 AICAR transformylase/IMP cyclohydrolase/methylglyoxal
synthase
Length = 591
Score = 987 bits (2552), Expect = 0.0
Identities = 493/589 (83%), Positives = 529/589 (89%), Gaps = 2/589 (0%)
Query: 3 HTKTAILSVYDKTGLLDLAKGLAENNVRILASGGTAKMVREAGFPVDDVSSITHAPEMLG 62
+TKTAILSVYDKTGLLDLAKGL ENNVRILASGGTA MVREAGFPVDDVSSITHAPEMLG
Sbjct: 4 YTKTAILSVYDKTGLLDLAKGLVENNVRILASGGTANMVREAGFPVDDVSSITHAPEMLG 63
Query: 63 GRVKTLHPAVHGGILARNLESDEKDLKEQNIDKVDFVVCNLYPFKETVAKVGVSIPEAVE 122
GRVKTLHPAVH GILARNLE DEKDLKEQ+IDKVDFVVCNLYPFKETVAK+GV++ EAVE
Sbjct: 64 GRVKTLHPAVHAGILARNLEGDEKDLKEQHIDKVDFVVCNLYPFKETVAKIGVTVQEAVE 123
Query: 123 EIDIGGVTLLRAAAKNHARVTILSDPKDYPQFLNELQK-GEISSDLRNTLALKAFEHTAD 181
EIDIGGVTLLRAAAKNH+RVTILSDP DY FL +L K GEIS DLRN ALKAFEHTAD
Sbjct: 124 EIDIGGVTLLRAAAKNHSRVTILSDPNDYSIFLQDLSKDGEISQDLRNRFALKAFEHTAD 183
Query: 182 YDTAISDFFRKQYSENKTQLALRYGANPHQKPAQAFVTQQEELPFKVLSGSPGYINLLDA 241
YD AISDFFRKQYSE K QL LRYG NPHQ+PAQA++TQQEELPFKVL G+PGYINLLDA
Sbjct: 184 YDAAISDFFRKQYSEGKAQLPLRYGCNPHQRPAQAYITQQEELPFKVLCGTPGYINLLDA 243
Query: 242 LNSWPLVKEXXXXXXXXXXXXFKHVSPAGAAVGLPLSDVEKQIYFVADIENLSPLACAYA 301
LNSWPLVKE FKHVSPAGAAVGLPLSDVE+Q+YFV D+E+LSPLACAYA
Sbjct: 244 LNSWPLVKELSASLNLPAAASFKHVSPAGAAVGLPLSDVERQVYFVNDMEDLSPLACAYA 303
Query: 302 RARGADRMSSFGDWIALSNIVDVPTAKIISREVSDGVIAPGFEPEALEILKKKKNGKYCI 361
RARGADRMSSFGD+IALSNIVDV TAKIIS+EVSDGVIAPG+EPEAL IL KKKNGKYCI
Sbjct: 304 RARGADRMSSFGDFIALSNIVDVATAKIISKEVSDGVIAPGYEPEALNILSKKKNGKYCI 363
Query: 362 LQIDPNYTPEALESRQVYGVTLQQKRNDAIINKSSFKEIVSQNKDLPEQAVIDLTVATIA 421
LQIDPNY P +ESR+V+GVTLQQKRNDAIIN+S+FKEIVS+NK L EQAVIDLTVAT+
Sbjct: 364 LQIDPNYVPGQMESREVFGVTLQQKRNDAIINQSTFKEIVSKNKALTEQAVIDLTVATLV 423
Query: 422 LKYTQSNSVCYAKNGMVVGLGAGQQSRIHCTRLAGDKADNWWLRQHPRVLGFKWAKGVKR 481
LKYTQSNSVCYAKNGMVVGLGAGQQSRIHCTRLAGDK DNWWLRQHP+VL KWAKG+KR
Sbjct: 424 LKYTQSNSVCYAKNGMVVGLGAGQQSRIHCTRLAGDKTDNWWLRQHPKVLNMKWAKGIKR 483
Query: 482 PEKSNAIDLFVTGQIPTEEPEKSEYESKFETIPEPLTAEEKKSWMSKLTNVALSSDAFFP 541
+KSNAIDLFVTGQ E PEK +YESKFE +PEP T EE+ W+SKL NV+LSSDAFFP
Sbjct: 484 ADKSNAIDLFVTGQ-RIEGPEKVDYESKFEEVPEPFTKEERLEWLSKLNNVSLSSDAFFP 542
Query: 542 FPDNVYRAVRSGVKYIAAPSGSVMDKAVFGAADSFDLVYVENPIRLFHH 590
FPDNVYRAV+SGVK+I APSGSVMDK VF AADSFD+VYVENPIRLFHH
Sbjct: 543 FPDNVYRAVQSGVKFITAPSGSVMDKVVFQAADSFDIVYVENPIRLFHH 591
>SPCPB16A4.03c [F] KOG2555 AICAR transformylase/IMP cyclohydrolase/methylglyoxal
synthase
Length = 585
Score = 835 bits (2156), Expect = 0.0
Identities = 410/584 (70%), Positives = 485/584 (82%), Gaps = 1/584 (0%)
Query: 7 AILSVYDKTGLLDLAKGLAENNVRILASGGTAKMVREAGFPVDDVSSITHAPEMLGGRVK 66
A+LSVYDKTGLL+LAK L V++L SGGTAKM+RE+G V DVSSIT+APE+LGGRVK
Sbjct: 3 ALLSVYDKTGLLELAKALTSKGVKLLGSGGTAKMIRESGMEVADVSSITNAPEILGGRVK 62
Query: 67 TLHPAVHGGILARNLESDEKDLKEQNIDKVDFVVCNLYPFKETVAKVGVSIPEAVEEIDI 126
TLHPAVHGGILAR++ SDEKDL EQ+I+K+D VVCNLYPF+ET+AK V+IPEAVEEIDI
Sbjct: 63 TLHPAVHGGILARDIPSDEKDLVEQSIEKIDIVVCNLYPFRETIAKPNVTIPEAVEEIDI 122
Query: 127 GGVTLLRAAAKNHARVTILSDPKDYPQFLNELQKGEISSDLRNTLALKAFEHTADYDTAI 186
GGVTLLRAAAKNHARVTILSDP DY F ++ +++ D RNT ALKAF TA YD AI
Sbjct: 123 GGVTLLRAAAKNHARVTILSDPADYATFTDKFLSDKLTQDDRNTYALKAFASTASYDAAI 182
Query: 187 SDFFRKQYSENKTQLALRYGANPHQKPAQAFVTQQEELPFKVLSGSPGYINLLDALNSWP 246
+D+FRKQY+ QL LRYGANPHQ PAQAF+ +Q LPFKVL GSPGYINL+DALNSWP
Sbjct: 183 TDYFRKQYAAGVDQLTLRYGANPHQSPAQAFM-EQGPLPFKVLCGSPGYINLMDALNSWP 241
Query: 247 LVKEXXXXXXXXXXXXFKHVSPAGAAVGLPLSDVEKQIYFVADIENLSPLACAYARARGA 306
LVKE FKHVSPAGAAVGLPLSDVEK++YFV+DI +PLACAYARARGA
Sbjct: 242 LVKELRENIGIPAAASFKHVSPAGAAVGLPLSDVEKKVYFVSDITEFTPLACAYARARGA 301
Query: 307 DRMSSFGDWIALSNIVDVPTAKIISREVSDGVIAPGFEPEALEILKKKKNGKYCILQIDP 366
DRMSSFGD+IALS+ VDV TA+IISREVSDGVIAPG+EPEALE+LKKKK GKYC+LQ+DP
Sbjct: 302 DRMSSFGDFIALSDTVDVCTARIISREVSDGVIAPGYEPEALELLKKKKGGKYCVLQMDP 361
Query: 367 NYTPEALESRQVYGVTLQQKRNDAIINKSSFKEIVSQNKDLPEQAVIDLTVATIALKYTQ 426
Y P +E+RQVYG++LQQ RN A I+ S F+++VS+NKDLP+ A+IDL +AT ALKYTQ
Sbjct: 362 KYVPAEIETRQVYGISLQQHRNHAKIDFSLFEKVVSKNKDLPKSALIDLVIATTALKYTQ 421
Query: 427 SNSVCYAKNGMVVGLGAGQQSRIHCTRLAGDKADNWWLRQHPRVLGFKWAKGVKRPEKSN 486
SNSVCYAKNGMVVGLGAGQQSRIHC RLAGDKADNWWLR HP+VLG ++ K KRPEKSN
Sbjct: 422 SNSVCYAKNGMVVGLGAGQQSRIHCNRLAGDKADNWWLRHHPKVLGMQFKKSAKRPEKSN 481
Query: 487 AIDLFVTGQIPTEEPEKSEYESKFETIPEPLTAEEKKSWMSKLTNVALSSDAFFPFPDNV 546
AIDL+V +P E E+ ++ES FETIPEPLT +E++ +++ +V +SDAFFPFPDN+
Sbjct: 482 AIDLYVLDAVPAEGSEREQWESAFETIPEPLTKKEREEFLATCKDVVCASDAFFPFPDNI 541
Query: 547 YRAVRSGVKYIAAPSGSVMDKAVFGAADSFDLVYVENPIRLFHH 590
YR +SGVKY+AAP GSVMD+AV A+ F++V+ E P+RLFHH
Sbjct: 542 YRLAQSGVKYVAAPGGSVMDQAVRDTANEFNMVFSEIPLRLFHH 585
>Hs20127454 [F] KOG2555 AICAR transformylase/IMP cyclohydrolase/methylglyoxal
synthase
Length = 592
Score = 703 bits (1814), Expect = 0.0
Identities = 356/588 (60%), Positives = 441/588 (74%), Gaps = 6/588 (1%)
Query: 7 AILSVYDKTGLLDLAKGLAENNVRILASGGTAKMVREAGFPVDDVSSITHAPEMLGGRVK 66
A+ SV DKTGL++ A+ L + ++ASGGTAK +R+AG V DVS +T PEMLGGRVK
Sbjct: 7 ALFSVSDKTGLVEFARNLTALGLNLVASGGTAKALRDAGLAVRDVSELTGFPEMLGGRVK 66
Query: 67 TLHPAVHGGILARNLESDEKDLKEQNIDKVDFVVCNLYPFKETVAKVGVSIPEAVEEIDI 126
TLHPAVH GILARN+ D D+ + + + V CNLYPF +TVA GV++ EAVE+IDI
Sbjct: 67 TLHPAVHAGILARNIPEDNADMARLDFNLIRVVACNLYPFVKTVASPGVTVEEAVEQIDI 126
Query: 127 GGVTLLRAAAKNHARVTILSDPKDYPQFLNELQKGE---ISSDLRNTLALKAFEHTADYD 183
GGVTLLRAAAKNHARVT++ +P+DY E+Q E S + R LALKAF HTA YD
Sbjct: 127 GGVTLLRAAAKNHARVTVVCEPEDYVVVSTEMQSSESKDTSLETRRQLALKAFTHTAQYD 186
Query: 184 TAISDFFRKQYSENKTQLALRYGANPHQKPAQAFVTQQEELPFKVLSGSPGYINLLDALN 243
AISD+FRKQYS+ +Q+ LRYG NPHQ PAQ + T Q +LP VL+G+PG+INL DALN
Sbjct: 187 EAISDYFRKQYSKGVSQMPLRYGMNPHQTPAQLY-TLQPKLPITVLNGAPGFINLCDALN 245
Query: 244 SWPLVKEXXXXXXXXXXXXFKHVSPAGAAVGLPLSDVEKQIYFVADI-ENLSPLACAYAR 302
+W LVKE FKHVSPAGAAVG+PLS+ E ++ V D+ + L+P++ AYAR
Sbjct: 246 AWQLVKELKEALGIPAAASFKHVSPAGAAVGIPLSEDEAKVCMVYDLYKTLTPISAAYAR 305
Query: 303 ARGADRMSSFGDWIALSNIVDVPTAKIISREVSDGVIAPGFEPEALEILKKKKNGKYCIL 362
ARGADRMSSFGD++ALS++ DVPTAKIISREVSDG+IAPG+E EAL IL KKKNG YC+L
Sbjct: 306 ARGADRMSSFGDFVALSDVCDVPTAKIISREVSDGIIAPGYEEEALTILSKKKNGNYCVL 365
Query: 363 QIDPNYTPEALESRQVYGVTLQQKRNDAIINKSSFKEIVSQNKDLPEQAVIDLTVATIAL 422
Q+D +Y P+ E R ++G+ L QKRN+ +++KS F +V++NKDLPE A+ DL VATIA+
Sbjct: 366 QMDQSYKPDENEVRTLFGLHLSQKRNNGVVDKSLFSNVVTKNKDLPESALRDLIVATIAV 425
Query: 423 KYTQSNSVCYAKNGMVVGLGAGQQSRIHCTRLAGDKADNWWLRQHPRVLGFKWAKGVKRP 482
KYTQSNSVCYAKNG V+G+GAGQQSRIHCTRLAGDKA+ WWLR HP+VL K+ GVKR
Sbjct: 426 KYTQSNSVCYAKNGQVIGIGAGQQSRIHCTRLAGDKANYWWLRHHPQVLSMKFKTGVKRA 485
Query: 483 EKSNAIDLFVTGQIPTEEPEKSEYESKFETIPEPLTAEEKKSWMSKLTNVALSSDAFFPF 542
E SNAID +VTG I E+ + ++++ FE +PE LT EKK W+ KLT V++SSDAFFPF
Sbjct: 486 EISNAIDQYVTGTI-GEDEDLIKWKALFEEVPELLTEAEKKEWVEKLTEVSISSDAFFPF 544
Query: 543 PDNVYRAVRSGVKYIAAPSGSVMDKAVFGAADSFDLVYVENPIRLFHH 590
DNV RA RSGV YIAAPSGS DK V A D ++ +RLFHH
Sbjct: 545 RDNVDRAKRSGVAYIAAPSGSAADKVVIEACDELGIILAHTNLRLFHH 592
>7301227 [F] KOG2555 AICAR transformylase/IMP cyclohydrolase/methylglyoxal
synthase
Length = 590
Score = 703 bits (1814), Expect = 0.0
Identities = 361/592 (60%), Positives = 437/592 (72%), Gaps = 4/592 (0%)
Query: 1 MPHTKTAILSVYDKTGLLDLAKGLAENNVRILASGGTAKMVREAGFPVDDVSSITHAPEM 60
M +K A+LSV DKTGLLDL K L ++ASGGTA +R AG V DVS IT APEM
Sbjct: 1 MSSSKIALLSVSDKTGLLDLGKSLVALGFDLVASGGTATSLRGAGLKVRDVSEITGAPEM 60
Query: 61 LGGRVKTLHPAVHGGILARNLESDEKDLKEQNIDKVDFVVCNLYPFKETVAKVGVSIPEA 120
LGGRVKTLHPAVH GIL+R +SD D+++Q D + VVCNLYPF TVAK V++ +A
Sbjct: 61 LGGRVKTLHPAVHAGILSRTTDSDLADMRKQGFDLIQLVVCNLYPFASTVAKPDVTLADA 120
Query: 121 VEEIDIGGVTLLRAAAKNHARVTILSDPKDYPQFLNELQ-KGEISSDLRNTLALKAFEHT 179
VE IDIGGVTLLRAAAKNH RVT++ + DY + L+EL+ G + + R LALKAF HT
Sbjct: 121 VENIDIGGVTLLRAAAKNHQRVTVVCEAVDYDRVLSELKASGNTTVETRQALALKAFTHT 180
Query: 180 ADYDTAISDFFRKQYSENKTQLALRYGANPHQKPAQAFVTQQEELPFKVLSGSPGYINLL 239
A YD AISD+FRKQY +QL LRYG NPHQKPAQ + TQ +LP VL+ SPG+INL
Sbjct: 181 ATYDDAISDYFRKQYGSGVSQLPLRYGMNPHQKPAQLY-TQLAKLPLTVLNASPGFINLC 239
Query: 240 DALNSWPLVKEXXXXXXXXXXXXFKHVSPAGAAVGLPLSDVEKQIYFVADI-ENLSPLAC 298
DALN W LV+E FKHVSPAGAAVG+PL+ + ++ V D+ E L+PLA
Sbjct: 240 DALNGWQLVRELKKALQLPAATSFKHVSPAGAAVGVPLNPAQAKLCMVDDLYEQLTPLAT 299
Query: 299 AYARARGADRMSSFGDWIALSNIVDVPTAKIISREVSDGVIAPGFEPEALEILKKKKNGK 358
AYARARGADRMSSFGD++ALS++ DV TA+IISREVSDG+IA G+EPEALEILKKKKNG
Sbjct: 300 AYARARGADRMSSFGDFVALSDVCDVVTARIISREVSDGIIAAGYEPEALEILKKKKNGG 359
Query: 359 YCILQIDPNYTPEALESRQVYGVTLQQKRNDAIINKSSFKEIVSQNKDLPEQAVIDLTVA 418
YCILQ+DPNY P A+E + ++G+TL+QKRNDA+I+ S F +VS+ LPE AV DL VA
Sbjct: 360 YCILQMDPNYEPSAVERKTIFGLTLEQKRNDAVIDASLFSNVVSKRGPLPEVAVRDLIVA 419
Query: 419 TIALKYTQSNSVCYAKNGMVVGLGAGQQSRIHCTRLAGDKADNWWLRQHPRVLGFKWAKG 478
TIALKYTQSNSVCYA++G VVG+GAGQQSRIHCTRLAG+KADNWWLRQHP V G K+ G
Sbjct: 420 TIALKYTQSNSVCYARDGQVVGIGAGQQSRIHCTRLAGEKADNWWLRQHPSVAGMKFKAG 479
Query: 479 VKRPEKSNAIDLFVTGQIPTEEPEKSEYESKFETIPEPLTAEEKKSWMSKLTNVALSSDA 538
VKR E SNAID +V G + + P S++E F+ P LT+E+K W+ +L+ VAL SDA
Sbjct: 480 VKRAEISNAIDNYVNGTVGKDMP-LSQFEGMFDKAPAQLTSEQKVEWLKQLSGVALGSDA 538
Query: 539 FFPFPDNVYRAVRSGVKYIAAPSGSVMDKAVFGAADSFDLVYVENPIRLFHH 590
FFPF DN+ RA SGV YIA+P+GS D V A D ++ +RLFHH
Sbjct: 539 FFPFRDNIDRASLSGVSYIASPAGSTNDAGVIAACDEHGIIMAHTNLRLFHH 590
>CE26363 [F] KOG2555 AICAR transformylase/IMP cyclohydrolase/methylglyoxal
synthase
Length = 498
Score = 437 bits (1125), Expect = e-122
Identities = 232/455 (50%), Positives = 288/455 (62%), Gaps = 39/455 (8%)
Query: 174 KAFEHTADYDTAISDFFRKQYSEN-KTQLALRYGANPHQKPAQAFVTQQEELPFKVLSGS 232
KAFEHT YD +IS F R++++ N + L LRYG NPHQK ++E+P KVL+GS
Sbjct: 45 KAFEHTTSYDESISGFMRRRFAGNGERALPLRYGTNPHQKDDAELYIVEDEMPIKVLNGS 104
Query: 233 PGYINLLDALNSWPLVKEXXXXXXXXXXXXFKHVSPAGAAVGLPLSDVEKQIYFVAD--I 290
PGYIN+LD LN W LVKE FKHVSPAGAAVGLPL++ E V+D I
Sbjct: 105 PGYINILDGLNGWQLVKELSDATKMPAAASFKHVSPAGAAVGLPLNETEAACCMVSDLPI 164
Query: 291 ENLSP-LACAYARARGADRMSSFGDWIALSNIVDVPTAKIISREVSDGVIAPGFEPEALE 349
+ P LA AYARARGADRMSSFGD+IALS D TAKII+REVSDGV+AP F+P AL
Sbjct: 165 DTKKPSLAAAYARARGADRMSSFGDFIALSEKCDELTAKIINREVSDGVVAPDFDPAALS 224
Query: 350 ILKKKKNGKYCILQIDPNYTPEALESRQVYGVTLQQKRNDAIINKSSFKEIVSQNKD--- 406
+L KKKNG YC+L+I+PNY P E R V+G+ L+QKRN+A+IN +F +V +
Sbjct: 225 LLAKKKNGNYCVLKINPNYLPSETEERTVFGLRLRQKRNNAVINAETFNNVVGSANEVSD 284
Query: 407 -------------------------------LPEQAVIDLTVATIALKYTQSNSVCYAKN 435
L +QA+ DL VATIALKY QSNSVC+A
Sbjct: 285 IRSLQIFKKHFMLSFLQNFHKYNCIKKSLFQLNKQAIDDLIVATIALKYAQSNSVCFAHR 344
Query: 436 GMVVGLGAGQQSRIHCTRLAGDKADNWWLRQHPRVLGFKWAKGVKRPEKSNAIDLFVTGQ 495
G V+G+GAGQQSRIHCTRLAGDKA NWWLRQHP VL W +KR EKSNAID+ +G
Sbjct: 345 GQVIGMGAGQQSRIHCTRLAGDKAMNWWLRQHPTVLSLPWKNAIKRSEKSNAIDVLCSGV 404
Query: 496 IPTEEPEKSEYESKFETIPEPLTAEEKKSWMSKLTNVALSSDAFFPFPDNVYRAVRSGVK 555
+ + E +++ F EPL +++K W+S+ T V +SSDAF PF DNV A + GV
Sbjct: 405 LGS-EIAIDQWQQYFNEPVEPLAEDDRKQWLSQQTGVVMSSDAFLPFRDNVDCAKQFGVS 463
Query: 556 YIAAPSGSVMDKAVFGAADSFDLVYVENPIRLFHH 590
Y+A P GSV D + A D + + +RLFHH
Sbjct: 464 YVAHPGGSVRDDDIKEACDEHGITLIHTGLRLFHH 498
>At2g35040 [F] KOG2555 AICAR transformylase/IMP cyclohydrolase/methylglyoxal
synthase
Length = 545
Score = 229 bits (585), Expect = 7e-60
Identities = 174/486 (35%), Positives = 238/486 (48%), Gaps = 59/486 (12%)
Query: 5 KTAILSVYDKTGLLDLAKGLAENNVRILASGGTAKMVREAGFPVDDVSSITHAPEMLGGR 64
K A++S+ DK L L GL E I+++GGTA + AG V V +TH PEML GR
Sbjct: 21 KQALISLSDKRDLASLGNGLQELGYTIVSTGGTASTLENAGVSVTKVEKLTHFPEMLDGR 80
Query: 65 VKTLHPAVHGGILA-RNLESDEKDLKEQNIDKVDFVVCNLYPFKETV-AKVGVSIPEAVE 122
VKTLHP +HGGILA R++E + L E I D VV NLYPF E V A G+S + +E
Sbjct: 81 VKTLHPNIHGGILARRDVEHHMEALNEHGIGTFDVVVVNLYPFYEKVTAPGGISFEDGIE 140
Query: 123 EIDIGGVTLLRAAAKNHARVTILSDPKDYPQFLNELQKGEISSDLRNTLALKAFEHTADY 182
IDIGG ++RAAAKNH V I+ D DY L L+ G+ R LA KAF+H A Y
Sbjct: 141 NIDIGGPAMIRAAAKNHKDVLIVVDSGDYQAVLEYLKGGQSDQQFRRKLAWKAFQHVAAY 200
Query: 183 DTAISDFFRKQYSENKTQL------------ALRYGANPHQKPAQAFVTQQEELPFKVLS 230
D+A+S++ KQ +E K + +LRYG NPHQK A E+ ++
Sbjct: 201 DSAVSEWLWKQ-TEGKEKFPPSFTVPLVLKSSLRYGENPHQKAAFYVDKSLAEVNAGGIA 259
Query: 231 GS-------PGYINLLDALNSWPLVKEXXXXXXXXXXXXFKHVSPAGAAVGLPLSDVEKQ 283
+ Y N LDA +W V E KH +P G A
Sbjct: 260 TAIQHHGKEMSYNNYLDADAAWNCVSE----FENPTCVVVKHTNPCGVA----------- 304
Query: 284 IYFVADIENLSPLACAYARARGADRMSSFGDWIALSNIVDVPTAKIIS--REVSDG---- 337
+ + AY A AD +S+FG +A + VD A+ I R +DG
Sbjct: 305 --------SRDDILEAYRLAVKADPVSAFGGIVAFNVEVDEVLAREIREFRSPTDGETRM 356
Query: 338 ----VIAPGFEPEALEILKKKKNGKYCILQIDPNYTPEALESRQVYGVTLQQKRNDAIIN 393
V+AP + + LE+LK K IL+ N L RQV G L Q +D
Sbjct: 357 FYEIVVAPKYTAKGLEVLKGKSK-TLRILEAKKN-DQGKLSLRQVGGGWLAQDSDDLTPE 414
Query: 394 KSSFKEIVSQNKDLPEQAVIDLTVATIALKYTQSNSVCYAKNGMVVGLGAGQQSRIHCTR 453
SF + +K E + D A + +K+ +SN++ AKN ++G+G+GQ +R+ R
Sbjct: 415 DISFNSV--SDKTPTESELADAKFAWLCVKHVKSNAIVIAKNNCMLGMGSGQPNRVESLR 472
Query: 454 LAGDKA 459
+A KA
Sbjct: 473 IAFKKA 478
>CE04899 [F] KOG2555 AICAR transformylase/IMP cyclohydrolase/methylglyoxal
synthase
Length = 267
Score = 193 bits (491), Expect = 5e-49
Identities = 96/151 (63%), Positives = 115/151 (75%)
Query: 7 AILSVYDKTGLLDLAKGLAENNVRILASGGTAKMVREAGFPVDDVSSITHAPEMLGGRVK 66
AI+SV DKTGL+ LA GL + ++ASGGTAK +R+ G V DV+ +T PEMLGGRVK
Sbjct: 29 AIISVSDKTGLIPLAHGLVSAGLTLIASGGTAKAIRDQGIDVHDVADVTKFPEMLGGRVK 88
Query: 67 TLHPAVHGGILARNLESDEKDLKEQNIDKVDFVVCNLYPFKETVAKVGVSIPEAVEEIDI 126
TLHPAVHGGILAR+ ESD KDL++ NI V VVCNLYPFK+TV S+ EAVE IDI
Sbjct: 89 TLHPAVHGGILARDTESDRKDLEKHNISFVSVVVCNLYPFKKTVQSKDCSVEEAVENIDI 148
Query: 127 GGVTLLRAAAKNHARVTILSDPKDYPQFLNE 157
GGVTLLRAAAKNH RV+++ DP DY ++E
Sbjct: 149 GGVTLLRAAAKNHERVSVICDPADYDHIISE 179
>Hs20468150 [F] KOG2555 AICAR transformylase/IMP cyclohydrolase/methylglyoxal
synthase
Length = 90
Score = 77.0 bits (188), Expect = 7e-14
Identities = 39/84 (46%), Positives = 52/84 (61%), Gaps = 1/84 (1%)
Query: 201 LALRYGANPHQKPAQAFVTQQEELPFKVLSGSPGYINLLDALNSWPLVKEXXXXXXXXXX 260
+ L+Y PHQ P Q + T + +LP VL+G+PG+ N DALN+W LVKE
Sbjct: 1 MPLQYRMIPHQTPVQLY-TLKPKLPITVLNGAPGFKNFCDALNAWQLVKELKEALGILSA 59
Query: 261 XXFKHVSPAGAAVGLPLSDVEKQI 284
FKHVSPA AAV +PLS+ E ++
Sbjct: 60 ALFKHVSPADAAVEIPLSENEAKV 83
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.316 0.134 0.385
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,964,134
Number of Sequences: 60738
Number of extensions: 1509352
Number of successful extensions: 3624
Number of sequences better than 1.0e-05: 9
Number of HSP's better than 0.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 3591
Number of HSP's gapped (non-prelim): 11
length of query: 590
length of database: 30,389,216
effective HSP length: 112
effective length of query: 478
effective length of database: 23,586,560
effective search space: 11274375680
effective search space used: 11274375680
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)