ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI4704 good P KOG2693 Inorganic ion transport and metabolism Putative zinc transporter
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI4704 1637484 1636435 -350
(350 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YIL023c [P] KOG2693 Putative zinc transporter 193 3e-49
CE18815 [P] KOG2693 Putative zinc transporter 151 1e-36
CE19807 [P] KOG2693 Putative zinc transporter 144 1e-34
7298525 [P] KOG2693 Putative zinc transporter 142 1e-33
SPAP8A3.03 [P] KOG2693 Putative zinc transporter 127 3e-29
Hs5901936 [P] KOG2693 Putative zinc transporter 119 5e-27
Hs17472948 [P] KOG2694 Putative zinc transporter 115 7e-26
7301851 [P] KOG2694 Putative zinc transporter 107 3e-23
Hs20473677 [P] KOG2693 Putative zinc transporter 100 4e-21
CE23542 [P] KOG2694 Putative zinc transporter 96 1e-19
7294338 [P] KOG2693 Putative zinc transporter 87 4e-17
Hs14727687 [P] KOG2693 Putative zinc transporter 78 2e-14
Hs12751475 [P] KOG2693 Putative zinc transporter 78 2e-14
Hs19115958 [P] KOG2693 Putative zinc transporter 75 2e-13
At1g68100 [P] KOG2693 Putative zinc transporter 72 1e-12
Hs20545152 [P] KOG2693 Putative zinc transporter 68 2e-11
Hs11545900 [P] KOG2693 Putative zinc transporter 67 3e-11
Hs8923305 [P] KOG2693 Putative zinc transporter 67 5e-11
7295075 [P] KOG2693 Putative zinc transporter 67 5e-11
CE15646 [P] KOG2693 Putative zinc transporter 66 7e-11
CE25496 [P] KOG2693 Putative zinc transporter 65 1e-10
CE12962 [U] KOG3907 ZIP-like zinc transporter proteins 57 3e-08
Hs8922968 [U] KOG3907 ZIP-like zinc transporter proteins 50 4e-06
7304319 [U] KOG3907 ZIP-like zinc transporter proteins 50 5e-06
CE28958 [P] KOG2693 Putative zinc transporter 49 8e-06
>YIL023c [P] KOG2693 Putative zinc transporter
Length = 346
Score = 193 bits (491), Expect = 3e-49
Identities = 110/304 (36%), Positives = 178/304 (58%), Gaps = 25/304 (8%)
Query: 53 LFPFSAKYNAMLATLYLCALPCILVAIIPGFKRG--GTKMVRLMVPFALGGILGDVFLHV 110
LF +YNA++A L + +PC+ V +PG ++ + + L+V F+LG +LGD+ LHV
Sbjct: 60 LFVLGPRYNAIVAILIIQLMPCLFVLFVPGLRKNDRASLTLSLLVSFSLGTLLGDILLHV 119
Query: 111 LPE-LYHEGDPVDIGYGILYGFLSFMAIDKLLRVINMGSPNXXXXXXXXXXXFDDDHLKQ 169
+PE L D +G I GF+SF+ +DK +R+++ G+ N DD
Sbjct: 120 IPESLSGVTDVTMVGGAIFLGFISFLTLDKTMRILS-GTSN-------------DDGSIH 165
Query: 170 STEEDKKPTGTQSSRSKTNNKSLEVSTYLNMVTEFIHKAADGIAVSSSFYTSKYVGIMSF 229
S P T ++ N +S YLN+++ H DGIA+++SFY+S VGIM+
Sbjct: 166 SHSHSHTPQQTAEKKAGFN-----MSAYLNVISGIAHHITDGIALATSFYSSTQVGIMTS 220
Query: 230 MAVVFHEVPHELGDFAVKLSSGLTFKQAIESELFTCLGSLTGAAIGCILNEMGKGNDELN 289
+AV FHE+PHELGDFA+ LSSG TF QAI ++ T G++ G +IGC +NE+G + +
Sbjct: 221 IAVTFHEIPHELGDFAILLSSGFTFPQAIRAQAVTAFGAVVGTSIGCWMNEIGNNSHKAT 280
Query: 290 NEEW-TNKIMI-ITCGGFIYTSTVGVVPELLNIST-NSRRKEITTTVIQIGCTLLGFYMM 346
+ +++M+ T GG IY +T VVP++L+ S +S+ +E +Q+ +GF +M
Sbjct: 281 SSSANASELMLPFTAGGLIYIATTSVVPQILHSSAPDSKLREFKKWALQLVFIFVGFAVM 340
Query: 347 SIIE 350
++++
Sbjct: 341 ALMD 344
>CE18815 [P] KOG2693 Putative zinc transporter
Length = 515
Score = 151 bits (382), Expect = 1e-36
Identities = 93/314 (29%), Positives = 162/314 (50%), Gaps = 42/314 (13%)
Query: 62 AMLATLYLCALPCILVAIIP---GFKRGGTKMVRLMVPFALGGILGDVFLHVLPELYHEG 118
A+ ATL + A PC ++ IP G ++++++ F GG+LGD FLH++P G
Sbjct: 214 AISATLLISAAPCFILMFIPIQANTSESGP-LLKVLLAFGSGGLLGDAFLHLIPHATPAG 272
Query: 119 D----------------------PVDIGYGILYGFLSFMAIDKLLRVINMGSPNXXXXXX 156
D + +G +L G ++F+ ++KL+R++ +
Sbjct: 273 DGHGHSHSHGHSHGGGGHSHGAHDMSVGGWVLGGIIAFLTVEKLVRILRGEDGHGHSHGH 332
Query: 157 XXXXXFDDDHLKQSTEEDKKP-TGTQSSRSKTNNKSLEVSTYLNMVTEFIHKAADGIAVS 215
K++ E+D K + + + + +S++V+ YLN+ +F H DG+A+
Sbjct: 333 SHGG-----EKKETKEKDSKDKVAKKEEKPEKDEQSIKVTAYLNLAADFTHNFTDGLAIG 387
Query: 216 SSFYTSKYVGIMSFMAVVFHEVPHELGDFAVKLSSGLTFKQAIESELFTCLGSLTGAAIG 275
+SF VGI++ + V+ HEVPHE+GDFA+ + SG + K+A+ +L T LG+L+ G
Sbjct: 388 ASFIAGTTVGIVTMITVLVHEVPHEIGDFAILIQSGYSKKKAMLIQLVTALGALS----G 443
Query: 276 CILNEMGKGNDELNNEEWTNKIMIITCGGFIYTSTVGVVPELLNISTNSRRKEITTTVIQ 335
C+++ D L + ++ ++ T GGFIY +TV V+PELL S+ TV +
Sbjct: 444 CVISLFSADADALADAAASSWVLPFTAGGFIYIATVSVIPELLENSS------FFQTVKE 497
Query: 336 IGCTLLGFYMMSII 349
I L G ++M +I
Sbjct: 498 IFAILTGIFLMYLI 511
>CE19807 [P] KOG2693 Putative zinc transporter
Length = 404
Score = 144 bits (364), Expect = 1e-34
Identities = 91/313 (29%), Positives = 154/313 (49%), Gaps = 37/313 (11%)
Query: 62 AMLATLYLCALPCILVAIIPGFKRGGTKMVRLMVPFALGGILGDVFLHVLPELY----HE 117
++ A + + PC L+ IP G +++++ F GG+LGD LH++P H
Sbjct: 87 SLSAVVGISLAPCTLLFFIPAQHANGP-FLKILLAFGAGGLLGDALLHIIPHSLSPHDHS 145
Query: 118 GDPVD-------------------IGYGILYGFLSFMAIDKLLRVINMGSPNXXXXXXXX 158
D D +G ++ G L FM +++L+R+I G +
Sbjct: 146 HDHHDHNHSHKEHDHSHDHSNQLRVGTFVIAGILVFMMVEQLVRIIKGGHCHSHENGHIV 205
Query: 159 XXXFDDDHLKQSTEEDKKPTGTQSSRSKTNNKSLEVSTYLNMVTEFIHKAADGIAVSSSF 218
+ HL + E + + + K ++ S YLN+V +F+H DG+A+ +SF
Sbjct: 206 AD--EHRHLNEHDHEHSE----EKKQQVEGLKDVKASAYLNLVADFVHNVTDGLAIGASF 259
Query: 219 YTSKYVGIMSFMAVVFHEVPHELGDFAVKLSSGLTFKQAIESELFTCLGSLTGAAIGCIL 278
+G ++ + V+ HE+PHE+GDFA+ + SG + QAI + T LG++TG ++
Sbjct: 260 SAGNTLGWITTLTVLLHELPHEVGDFAILVQSGFSKYQAIRLQAVTALGAITGCVFSLLV 319
Query: 279 NEMGKGNDELNNEEWTNKIMIITCGGFIYTSTVGVVPELLNISTN---SRRKEITTTVIQ 335
+ G LNN+ T+ IM T GGFIY +TV VVPELL + S+ ++ +++
Sbjct: 320 SNPG----SLNNDADTSAIMPFTAGGFIYIATVSVVPELLESGDHNNLSKVAKMAQSLVH 375
Query: 336 IGCTLLGFYMMSI 348
+ +G MM I
Sbjct: 376 VLAICMGVGMMYI 388
>7298525 [P] KOG2693 Putative zinc transporter
Length = 449
Score = 142 bits (357), Expect = 1e-33
Identities = 94/321 (29%), Positives = 163/321 (50%), Gaps = 49/321 (15%)
Query: 65 ATLYLCALPCILVAIIPGFKRGGTK-MVRLMVPFALGGILGDVFLHVLPEL--------- 114
+TL + A P +L+ IIP K +++++ FA GG+LGD FLH++P
Sbjct: 138 STLLISAAPFVLLYIIPLDNSEAMKPRLKVLLAFASGGLLGDAFLHLIPHATHPHSHGEH 197
Query: 115 ----------YHEGDP--------VDIGYGILYGFLSFMAIDKLLRVINMGSPNXXXXXX 156
+H+G+ + IG +L G ++F++++KL+R++ G
Sbjct: 198 GHDHGHDHHHHHDGEEHEHGHSHDMSIGLWVLGGIIAFLSVEKLVRILKGGHGGHGHSHG 257
Query: 157 XXXXXFDDDHLKQSTEEDK-------KPTGTQSSRSKTNNKS-LEVSTYLNMVTEFIHKA 208
K S +ED KP +S + + + +E+S YLN+ +F H
Sbjct: 258 APKPKPVPAKKKSSDKEDSGDGDKPAKPAKIKSKKPEAEPEGEVEISGYLNLAADFAHNF 317
Query: 209 ADGIAVSSSFYTSKYVGIMSFMAVVFHEVPHELGDFAVKLSSGLTFKQAIESELFTCLGS 268
DG+A+ +S+ +GI++ + ++ HEVPHE+GDFA+ + SG + ++A+ +L T LG+
Sbjct: 318 TDGLAIGASYLAGNSIGIVTTITILLHEVPHEIGDFAILIKSGCSRRKAMLLQLVTALGA 377
Query: 269 LTGAAIGCILNEMGKGNDELNNEEWTNKIMIITCGGFIYTSTVGVVPELLNISTNSRRKE 328
L G A+ +G G + + W ++ T GGFIY +TV V+PELL ST +
Sbjct: 378 LAGTALAL----LGAGGGD-GSAPW---VLPFTAGGFIYIATVSVLPELLEEST-----K 424
Query: 329 ITTTVIQIGCTLLGFYMMSII 349
+ ++ +I L G +M +I
Sbjct: 425 LKQSLKEIFALLTGVALMIVI 445
>SPAP8A3.03 [P] KOG2693 Putative zinc transporter
Length = 453
Score = 127 bits (318), Expect = 3e-29
Identities = 89/314 (28%), Positives = 148/314 (46%), Gaps = 32/314 (10%)
Query: 36 NSFQQLNNGAVIQYLQLLFPFSAKYNAMLATLYLCALPCILVAIIPGFKRGGTKMVRLMV 95
NS LN+ V +++ F +S+ N +LAT P I + ++P K T M+ L V
Sbjct: 115 NSCVWLNS--VKSFVEKQFSYSSGTNGILATFLTAIPPNIFILLVP--KSFDTSMLNLFV 170
Query: 96 PFALGGILGDVFLHVLPELY--HEGD-PVDIGYGILYGFLSFMAIDKLLRVINMGSPNXX 152
+ G +LGDVFL +LP +Y + GD P Y IL G L F +DK +R++ P+
Sbjct: 171 AVSAGSLLGDVFLQLLPTVYSTNGGDFPASSVYSILIGALVFFLMDKGIRILIHERPSSL 230
Query: 153 XXXXXXXXXFDDDHLKQSTEEDKKPTGTQSSRSKT-----NNKSLE-------------- 193
+ ++ G + R + N+K E
Sbjct: 231 SKPKKDGEETSSVNKPSASSTQTDVKGVEGLRKRNVKDDQNSKGHEPDLIRHVVEEVSEE 290
Query: 194 ----VSTYLNMVTEFIHKAADGIAVSSSFYTSKYVGIMSFMAVVFHEVPHELGDFAVKLS 249
YLN++ + H DG+A++S+F+T+ +GI + AV+ HE+P E+GD A+ L
Sbjct: 291 YNDKTVVYLNLLCDSFHNFMDGLAITSAFFTNTSIGISTTFAVLLHEIPAEIGDLAILLR 350
Query: 250 SGLTFKQAIESELFTCLGSLTGAAIGCILNEMGKGNDELNN--EEWTNKIMIITCGGFIY 307
+G T Q + ++ T + L GA + + + + + +K++ T GGF+Y
Sbjct: 351 NGYTKSQVLVLQMITMVTGLLGAIVATYIYTASSSSSPYGSFLLQLEDKLLPFTAGGFLY 410
Query: 308 TSTVGVVPELLNIS 321
+ +GV PELL I+
Sbjct: 411 IAYLGVFPELLEIN 424
>Hs5901936 [P] KOG2693 Putative zinc transporter
Length = 429
Score = 119 bits (299), Expect = 5e-27
Identities = 78/286 (27%), Positives = 132/286 (45%), Gaps = 57/286 (19%)
Query: 62 AMLATLYLCALPCILVAIIPGFKRGGT--KMVRLMVPFALGGILGDVFLHVLPELYH--- 116
A+ AT+ + A P ++ +IP ++++++ FA GG+LGD FLH++P
Sbjct: 138 ALGATVLISAAPFFVLFLIPVESNSPRHRSLLQILLSFASGGLLGDAFLHLIPHALEPHS 197
Query: 117 ---------------EGDPVDIGYGILYGFLSFMAIDKLLRVINMGSPNXXXXXXXXXXX 161
+G + +G +L G ++F+ ++K +R + G +
Sbjct: 198 HHTLEQPGHGHSHSGQGPILSVGLWVLSGIVAFLVVEKFVRHVKGGHGHSHGHGHAHSHT 257
Query: 162 FDDD---------HLKQSTEEDKK------------------PTGTQSSRSKTNNKSLEV 194
KQS+EE+ K P Q++ + L V
Sbjct: 258 RGSHGHGRQERSTKEKQSSEEEGKETRGVQKRRGGSTVPKDGPVRPQNAEEEKRGLDLRV 317
Query: 195 STYLNMVTEFIHKAADGIAVSSSFYTSKYVGIMSFMAVVFHEVPHELGDFAVKLSSGLTF 254
S YLN+ + H DG+A+ +SF + +GI++ M V+ HEVPHE+GDFA+ + SG T
Sbjct: 318 SGYLNLAADLAHNFTDGLAIGASFRGGRGLGILTTMTVLLHEVPHEVGDFAILVQSGCTK 377
Query: 255 KQAIESELFTCLGSLTGAAIGCILNEMGKGNDELNNEEWTNKIMII 300
KQA+ +L T +G+L G A+ L E E+WT K+ ++
Sbjct: 378 KQAMRLQLLTAVGALAGTAVPFSLKE----------EQWTVKLQVV 413
>Hs17472948 [P] KOG2694 Putative zinc transporter
Length = 371
Score = 115 bits (289), Expect = 7e-26
Identities = 78/260 (30%), Positives = 127/260 (48%), Gaps = 48/260 (18%)
Query: 87 GTKMVRLMVPFALGGILGDVFLHVLPELYH---------EGDPVD----IGYGILYGFLS 133
G ++ ++ FALGG+LG+VFLH+LPE + EG + +G ++ G L+
Sbjct: 102 GAWRLKQLLSFALGGLLGNVFLHLLPEAWAYTCSASPGGEGQSLQQQQQLGLWVIAGILT 161
Query: 134 FMAIDKLLRVINMGSPNXXXXXXXXXXXFDDDHLKQSTEEDKKPTGTQSSRSKTNN---- 189
F+A++K+ D S +K PT ++ + +
Sbjct: 162 FLALEKMF--------------------LDSKEEGTSQAPNKDPTAAAAALNGGHCLAQP 201
Query: 190 ----------KSLEVSTYLNMVTEFIHKAADGIAVSSSFYTSKYVGIMSFMAVVFHEVPH 239
+S++VS YLN++ I G+AV++SF SK +G+++ MA++ HE+PH
Sbjct: 202 AAEPGLGAVVRSIKVSGYLNLLANTIDNFTHGLAVAASFLVSKKIGLLTTMAILLHEIPH 261
Query: 240 ELGDFAVKLSSGLTFKQAIESELFTCLGSLTGAAIG-CILNEMGKGNDELNNEEWTNKIM 298
E+GDFA+ L +G A + +L T LG L GA C + G EE ++
Sbjct: 262 EVGDFAILLRAGFDRWSAAKLQLSTALGGLLGAGFAICTQSPKGVVGCSPAAEETAAWVL 321
Query: 299 IITCGGFIYTSTVGVVPELL 318
T GGF+Y + V V+P+LL
Sbjct: 322 PFTSGGFLYIALVNVLPDLL 341
>7301851 [P] KOG2694 Putative zinc transporter
Length = 355
Score = 107 bits (267), Expect = 3e-23
Identities = 87/288 (30%), Positives = 137/288 (47%), Gaps = 38/288 (13%)
Query: 88 TKMVRLMVPFALGGILGDVFLHVLPELYHEGDPVD--------IGYGILYGFLSFMAIDK 139
+K++R+++ FA+GG+LGDVFLH+LPE + EGD D G +L G L F ++K
Sbjct: 74 SKLLRVLLSFAVGGLLGDVFLHLLPEAW-EGDNQDPSSHPSLRSGLWVLSGILIFTIVEK 132
Query: 140 LLR-VINMGSPNXXXXXXXXXXXFDDDHLKQSTE-EDKKPTG---------------TQS 182
+ + N H Q E E + G Q
Sbjct: 133 IFSGYASADEENPQPKCVEIANCLLRRHGGQLPEGETSESCGGACDIEDVGKVCFLREQE 192
Query: 183 SRSKTNNKS-LEVSTYLNMVTEFIHKAADGIAVSSSFYTSKYVGIMSFMAVVFHEVPHEL 241
+SK + +V+ YLN++ I G+AV+ SF S GI++ A++ HE+PHE+
Sbjct: 193 QKSKERKEQPKKVAGYLNLLANSIDNFTHGLAVAGSFLVSFRHGILATFAILLHEIPHEV 252
Query: 242 GDFAVKLSSGLTFKQAIESELFTCLGSLTGAAIGCILNEMGKGNDELNNEEWTNKIMIIT 301
GDFA+ L SG + A ++L T L GA + +G E T+ IM T
Sbjct: 253 GDFAILLRSGFSRWDAARAQLLTAGAGLLGALVA-----IGGSGVTSAMEARTSWIMPFT 307
Query: 302 CGGFIYTSTVGVVPELLNISTNSRRKEITTTVIQIGCTLLGFYMMSII 349
GGF++ + V V+P+LL RKE ++ Q+ + G +M+++
Sbjct: 308 AGGFLHIALVTVLPDLLK---EEERKE---SIKQLLALVFGIALMAVM 349
>Hs20473677 [P] KOG2693 Putative zinc transporter
Length = 654
Score = 100 bits (248), Expect = 4e-21
Identities = 68/247 (27%), Positives = 126/247 (50%), Gaps = 39/247 (15%)
Query: 90 MVRLMVPFALGGILGDVFLHVLPELY--HEGDPVDIGY------------GILYGFLSFM 135
+++L V A+G + GD LH++P++ H+ + + G+ G++ G F
Sbjct: 400 ILQLFVGLAVGTLSGDALLHLIPQVLGLHKQEAPEFGHFHESKGHIWKLMGLIGGIHGFF 459
Query: 136 AIDKLLRVINMGSPNXXXXXXXXXXXFDDDHLKQSTEEDKKPTGTQSSRSKTNNKSLEVS 195
I+K I + SPN D + ++ + P G+ ++ S K++ +
Sbjct: 460 LIEKCF--ILLVSPN-------------DKKSPEDSQAAEMPIGSMTA-SNRKCKAISLL 503
Query: 196 TYLNMVTEFIHKAADGIAVSSSFYTSKYVGIMSFMAVVFHEVPHELGDFAVKLSSGLTFK 255
+ +V + +H ADG+A+ ++F +S G+ + +A++ HE+PHE+GDFAV LSSGL+ K
Sbjct: 504 AIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMGDFAVLLSSGLSMK 563
Query: 256 QAIESELFTCLGSLTGAAIGCILNEMGKGNDELNNEEWTNKIMIITCGGFIYTSTVGVVP 315
AI + L + G IG ++ + ++W I +T G F+Y S V ++P
Sbjct: 564 TAILMNFISSLTAFMGLYIGLSVSA------DPCVQDW---IFTVTAGMFLYLSLVEMLP 614
Query: 316 ELLNIST 322
E+ ++ T
Sbjct: 615 EMTHVQT 621
>CE23542 [P] KOG2694 Putative zinc transporter
Length = 362
Score = 95.5 bits (236), Expect = 1e-19
Identities = 70/251 (27%), Positives = 114/251 (44%), Gaps = 47/251 (18%)
Query: 87 GTKMVRLMVPFALGGILGDVFLHVLPELYHEGDP-VDIGYGILYGFLSFMAIDKLLRVIN 145
G + + L++ FA+G +L DVFLH+LPE Y + V IG +L G+L+F I KL
Sbjct: 143 GQRRLNLLLGFAIGSLLADVFLHLLPEAYESNENHVSIGLCVLAGYLTFSLISKLA---- 198
Query: 146 MGSPNXXXXXXXXXXXFDDDHLKQSTEEDKKPTGTQSSRSKTNNKSLEVSTYLNMVTEFI 205
S+EE++ ++ ++ L YLN+
Sbjct: 199 ------------------------SSEEEQH-------KASSSAHFLNACAYLNLFANIG 227
Query: 206 HKAADGIAVSSSFYTSKYVGIMSFMAVVFHEVPHELGDFAVKLSSGLTFKQAIESELFTC 265
A G+AV SSF S GIM+ + ++ HE+PHE+ DFA+ L + AI ++L T
Sbjct: 228 DNFAHGLAVGSSFLVSTKFGIMTTITILLHEIPHEISDFAILLRADFGKTNAILAQLTTA 287
Query: 266 LGSLTGAAIGCILNEMGKGNDELNNEEWTNKIMIITCGGFIYTSTVGVVPELLNISTNSR 325
+ G+ + L+ +N ++ T GGF+ + ++PE IS +
Sbjct: 288 AFGVLGSLVALHLH--------TSNVPVIETLLPFTAGGFLNIALTELLPE---ISAETS 336
Query: 326 RKEITTTVIQI 336
EI ++ I
Sbjct: 337 PVEILKQLVMI 347
>7294338 [P] KOG2693 Putative zinc transporter
Length = 519
Score = 87.0 bits (214), Expect = 4e-17
Identities = 73/322 (22%), Positives = 140/322 (42%), Gaps = 43/322 (13%)
Query: 62 AMLATLYLCALPCILVAIIPGFKRGG-TKMVRLMVPFALGGILGDVFLHVLP-----ELY 115
A + L L A + + ++P K ++++ +V A+G + GD +H+LP E
Sbjct: 193 ASITMLILSACGLLGILLVPLMKSAAYQEILKFLVSIAVGTLAGDALMHLLPHALFKEEK 252
Query: 116 HEGDPVDI-----------------GYGILYGFLSFMAIDKLLRVINMGSP-NXXXXXXX 157
HE + I G L +M ++ L+ ++ G P +
Sbjct: 253 HEEEVTGINPLESDHKHSNEAALLCGCTFLAALFMYM-LENLIPLLKGGKPGHGHSHGHG 311
Query: 158 XXXXFDDDHLKQSTEED--------KKPTGTQSSR--SKTNNKSLEVSTYLNMVTEFIHK 207
H+++ +D + Q ++ KT ++ L ++ ++ + +H
Sbjct: 312 HSHGRSHGHMEKPAAKDAIDLPPPRELNVMLQEAKLDEKTPDRPLTPVAFMVIIGDGLHN 371
Query: 208 AADGIAVSSSFYTSKYVGIMSFMAVVFHEVPHELGDFAVKLSSGLTFKQAIESELFTCLG 267
DG+A+ ++F + G + AV+ HE+PHELGDFA+ L +G++ ++A+ + + +
Sbjct: 372 LTDGLAIGAAFASDPVTGFATAFAVLCHELPHELGDFALLLQTGVSMRRAVYMNIVSSVL 431
Query: 268 SLTGAAIGCILNEMGKGNDELNNEEWTNKIMIITCGGFIYTSTVGVVPELLNISTNSRRK 327
S G ++G + +G G T I T G F+Y + +VP + + K
Sbjct: 432 SFVGMSVGLFIAGIGDG--------MTQWIYAATAGSFLYIAFADLVPTMSVAHNPEKAK 483
Query: 328 EITTTVIQIGCTLLGFYMMSII 349
+ +IQI LLG +M I
Sbjct: 484 DPKGIIIQIFGILLGGLIMLAI 505
>Hs14727687 [P] KOG2693 Putative zinc transporter
Length = 831
Score = 77.8 bits (190), Expect = 2e-14
Identities = 51/152 (33%), Positives = 79/152 (51%), Gaps = 19/152 (12%)
Query: 205 IHKAADGIAVSSSFYTSKYVGIMSFMAVVFHEVPHELGDFAVKLSSGLTFKQAIE----S 260
IH +DG+A+ ++F GI + +AV HE+PHELGDFAV L +G+T KQAI S
Sbjct: 679 IHNFSDGLAIGAAFSAGLTGGISTSIAVFCHELPHELGDFAVLLKAGMTVKQAIVYNLLS 738
Query: 261 ELFTCLGSLTGAAIGCILNEMGKGNDELNNEEWTNKIMIITCGGFIYTSTVGVVPELLNI 320
+ +G L G A+G N + T I +T G F+Y + V ++PE+L+
Sbjct: 739 AMMAYIGMLIGTAVGQYANNI------------TLWIFAVTAGMFLYVALVDMLPEMLHG 786
Query: 321 STNSRRK---EITTTVIQIGCTLLGFYMMSII 349
++ + ++Q L GF +M +I
Sbjct: 787 DGDNEEHGFCPVGQFILQNLGLLFGFAIMLVI 818
>Hs12751475 [P] KOG2693 Putative zinc transporter
Length = 749
Score = 77.8 bits (190), Expect = 2e-14
Identities = 51/168 (30%), Positives = 88/168 (52%), Gaps = 9/168 (5%)
Query: 183 SRSKTNNKSLEVSTYLNMVTEFIHKAADGIAVSSSFYTSKYVGIMSFMAVVFHEVPHELG 242
SR + + + ++ ++ + +H +DG+A+ ++F G+ + +AV HE+PHELG
Sbjct: 577 SREELKDAGVATLAWMVIMGDGLHNFSDGLAIGAAFTEGLSSGLSTSVAVFCHELPHELG 636
Query: 243 DFAVKLSSGLTFKQAIESELFTCLGSLTGAAIGCILNEMGKGNDELNNEEWTNKIMIITC 302
DFAV L +G+T KQA+ + + + G A G + G+ N W I +T
Sbjct: 637 DFAVLLKAGMTVKQAVLYNALSAMLAYLGMATGIFI-----GHYAENVSMW---IFALTA 688
Query: 303 GGFIYTSTVGVVPELL-NISTNSRRKEITTTVIQIGCTLLGFYMMSII 349
G F+Y + V +VPE+L N +++ +Q LLGF +M +I
Sbjct: 689 GLFMYVALVDMVPEMLHNDASDHGCSRWGYFFLQNAGMLLGFGIMLLI 736
>Hs19115958 [P] KOG2693 Putative zinc transporter
Length = 647
Score = 74.7 bits (182), Expect = 2e-13
Identities = 71/290 (24%), Positives = 120/290 (40%), Gaps = 42/290 (14%)
Query: 64 LATLY--LCALPCILVAIIPGFKRGGTKMVRLMVPFALGGILGDVFLHVLPELY------ 115
LATL LCA+ +L+ G + +++ + A+G + GD LH+ P++
Sbjct: 332 LATLLICLCAVFGLLLLTCTGCRGVAHYILQTFLSLAVGALTGDAVLHLTPKVLGLHTHS 391
Query: 116 HEG---DPVDIGYGILYGFLSFMAIDKLLRVINMGSPNXXXXXXXXXXXFDDD------- 165
EG P +L G +F + L ++ P
Sbjct: 392 EEGLSPQPTWRLLAMLAGLYAFFLFENLFNLLLPRDPEDLEDGPCGHSSHSHGGHSHGVS 451
Query: 166 -HLKQSTEEDKKPTGTQSSRSKTNNKS--------------LEVSTYLNMVTEFIHKAAD 210
L S KP S +S L + Y+ + + +H AD
Sbjct: 452 LQLAPSELRQPKPPHEGSRADLVAEESPELLNPEPRRLSPELRLLPYMITLGDAVHNFAD 511
Query: 211 GIAVSSSFYTSKYVGIMSFMAVVFHEVPHELGDFAVKLSSGLTFKQAIESELFTCLGSLT 270
G+AV ++F +S G+ + +AV HE+PHELGDFA L +GL+ +QA+ L + L +
Sbjct: 512 GLAVGAAFASSWKTGLATSLAVFCHELPHELGDFAALLHAGLSVRQALLLNLASALTAFA 571
Query: 271 GAAIGCILNEMGKGNDELNNEEWTNKIMIITCGGFIYTSTVGVVPELLNI 320
G + + G E +E W I+ + G F+Y + ++P +L +
Sbjct: 572 GLYVA-----LAVGVSE-ESEAW---ILAVATGLFLYVALCDMLPAMLKV 612
>At1g68100 [P] KOG2693 Putative zinc transporter
Length = 450
Score = 72.0 bits (175), Expect = 1e-12
Identities = 56/194 (28%), Positives = 95/194 (48%), Gaps = 27/194 (13%)
Query: 170 STEEDKKPTGTQSSRSKTNNKSLEVST--------YLNMVTEFIHKAADGIAVSSSFYTS 221
S DK +GT+ + ++K +V T YLN+ ++ +H DG+A+ S+F
Sbjct: 271 SDATDKSDSGTEITSDGKSDKPEQVETRSSSLVFGYLNLFSDGVHNFTDGMALGSAFLIY 330
Query: 222 KYVGIMS-FMAVVFHEVPHELGDFAVKLSSGLTFKQAIESELFTCLGSLTGAAIGCIL-N 279
VG S M ++ HE+P E+GDF + + SG T +A+ + L +L G A+ + N
Sbjct: 331 GSVGGWSRTMFLLAHELPQEIGDFGILVRSGFTVTKALFFNFLSALVALAGTALVLVWGN 390
Query: 280 EMGKGNDELNNEEWTNKIMIITCGGFIYTSTVGVVPELLNISTNSRRKEITTTVIQIGCT 339
E G+ ++ I T GGFIY + GV+ E+ NS + + + +
Sbjct: 391 EPGQ----------SSLIEGFTAGGFIYIAVAGVLAEM----NNSGKSTLKNSACHLISL 436
Query: 340 LLGFYM---MSIIE 350
+LG + +S+IE
Sbjct: 437 ILGMSVALCISLIE 450
>Hs20545152 [P] KOG2693 Putative zinc transporter
Length = 492
Score = 68.2 bits (165), Expect = 2e-11
Identities = 45/161 (27%), Positives = 77/161 (46%), Gaps = 14/161 (8%)
Query: 193 EVSTYLNMVT--EFIHKAADGIAVSSSFYTSKYVGIMSFMAVVFHEVPHELGDFAVKLSS 250
++ T M+T + +H DG+A+ +SF S + GI + +A++ E PHELGDF + L++
Sbjct: 332 DIGTLAWMITLSDGLHNFIDGLAIGASFTVSVFQGISTSVAILCEEFPHELGDFVILLNA 391
Query: 251 GLTFKQAIESELFTCLGSLTGAAIGCILNEMGKGNDELNNEEWTNKIMIITCGGFIYTST 310
G++ +QA+ + G A G + N W I + G F+Y S
Sbjct: 392 GMSIQQALFFNFLSACCCYLGLAFGILAGSHFSAN-------W---IFALAGGMFLYISL 441
Query: 311 VGVVPELLNISTNSRRKE--ITTTVIQIGCTLLGFYMMSII 349
+ PE+ + RK + +IQ L GF +M ++
Sbjct: 442 ADMFPEMNEVCQEDERKGSILIPFIIQNLGLLTGFTIMVVL 482
>Hs11545900 [P] KOG2693 Putative zinc transporter
Length = 460
Score = 67.4 bits (163), Expect = 3e-11
Identities = 46/165 (27%), Positives = 77/165 (45%), Gaps = 15/165 (9%)
Query: 190 KSLEVSTYLNMVT--EFIHKAADGIAVSSSFYTSKYVGIMSFMAVVFHEVPHELGDFAVK 247
K E+ T M+T + +H DG+A+ +S S G+ + +A++ E PHELGDF +
Sbjct: 296 KLSEIGTIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHELGDFVIL 355
Query: 248 LSSGLTFKQAIESELFTCLGSLTGAAIGCILNEMGKGNDELNNEEWTNKIMIITCGGFIY 307
L++G++ +QA+ + G A G + + N N I + G F+Y
Sbjct: 356 LNAGMSTRQALLFNFLSACSCYVGLAFGIL----------VGNNFAPNIIFALAGGMFLY 405
Query: 308 TSTVGVVPE---LLNISTNSRRKEITTTVIQIGCTLLGFYMMSII 349
S + PE +L R+ + T +IQ L GF + +I
Sbjct: 406 ISLADMFPEMNDMLREKVTGRKTDFTFFMIQNAGMLTGFTAILLI 450
>Hs8923305 [P] KOG2693 Putative zinc transporter
Length = 626
Score = 66.6 bits (161), Expect = 5e-11
Identities = 61/241 (25%), Positives = 99/241 (40%), Gaps = 33/241 (13%)
Query: 64 LATLY--LCALPCILVAIIPGFKRGGTKMVRLMVPFALGGILGDVFLHVLPELY------ 115
LATL LCA+ +L+ G + +++ + A+G + GD LH+ P++
Sbjct: 307 LATLLICLCAVFGLLLLTCTGCRGVAHYILQTFLSLAVGALTGDAVLHLTPKVLGLHTHS 366
Query: 116 HEG---DPVDIGYGILYGFLSFMAIDKLLRVINMGSPNXXXXXXXXXXXFDDD------- 165
EG P +L G +F + L ++ P
Sbjct: 367 EEGLSPQPTWRLLAMLAGLYAFFLFENLFNLLLPRDPEDLEDGPCGHSSHSHGGHSHGVS 426
Query: 166 -HLKQSTEEDKKPTGTQSSRSKTNNKS--------------LEVSTYLNMVTEFIHKAAD 210
L S KP S +S L + Y+ + + +H AD
Sbjct: 427 LQLAPSELRQPKPPHEGSRADLVAEESPELLNPEPRRLSPELRLLPYMITLGDAVHNFAD 486
Query: 211 GIAVSSSFYTSKYVGIMSFMAVVFHEVPHELGDFAVKLSSGLTFKQAIESELFTCLGSLT 270
G+AV ++F +S G+ + +AV HE+PHELGDFA L +GL+ +QA+ L + L +
Sbjct: 487 GLAVGAAFASSWKTGLATSLAVFCHELPHELGDFAALLHAGLSVRQALLLNLASALTAFA 546
Query: 271 G 271
G
Sbjct: 547 G 547
>7295075 [P] KOG2693 Putative zinc transporter
Length = 684
Score = 66.6 bits (161), Expect = 5e-11
Identities = 41/160 (25%), Positives = 81/160 (50%), Gaps = 14/160 (8%)
Query: 190 KSLEVSTYLNMVTEFIHKAADGIAVSSSFYTSKYVGIMSFMAVVFHEVPHELGDFAVKLS 249
++L ++ ++ + +H DG+A+ ++F + G + +AV HE+PHELGDFA+ +
Sbjct: 516 ETLSAVAWMIIMGDGLHNFTDGMAIGAAFAENIAGGFSTSLAVFCHELPHELGDFAILIK 575
Query: 250 SGLTFKQAIESELFTCLGSLTGAAIGCILNEMGKGNDELNNEEWTNKIMIITCGGFIYTS 309
+G++ K A+ L T + S G G + +++ + + G FIY +
Sbjct: 576 AGMSVKSAVYYNLLTGVLSFIGMIFGIAFGQ---------SQDVAQWMFAVAAGLFIYIA 626
Query: 310 TVGVVPELLNISTNSRRKEITTTVIQIGCTLLGFYMMSII 349
V ++PE+ ++ K + ++QI L G +M +I
Sbjct: 627 LVDMMPEI-----SASHKSLGQFLLQILGMLSGVGIMLLI 661
>CE15646 [P] KOG2693 Putative zinc transporter
Length = 360
Score = 66.2 bits (160), Expect = 7e-11
Identities = 36/107 (33%), Positives = 58/107 (53%), Gaps = 9/107 (8%)
Query: 205 IHKAADGIAVSSSFYTSKYVGIMSFMAVVFHEVPHELGDFAVKLSSGLTFKQAIESELFT 264
+H DG+A+ +SF S +G ++ +AV+ HE+PHE+GD AV + SGL+ A+ L +
Sbjct: 243 VHNLVDGLAMGASFMISVKLGFITTIAVICHELPHEIGDLAVLIDSGLSMCTALILNLLS 302
Query: 265 CLGSLTGAAIGCILNEMGKGNDELNNEEWTNKIMIITCGGFIYTSTV 311
L + G I +L +EE ++ IT G F+Y + V
Sbjct: 303 ALTAYAGLFIAIVLG---------RDEEIETILLAITAGMFLYVAWV 340
>CE25496 [P] KOG2693 Putative zinc transporter
Length = 157
Score = 65.1 bits (157), Expect = 1e-10
Identities = 38/114 (33%), Positives = 61/114 (53%), Gaps = 10/114 (8%)
Query: 205 IHKAADGIAVSSSFYTSKYVGIMSFMAVVFHEVPHELGDFAVKLSSGLTFKQAIESELFT 264
+H DGI++ ++F S + G+ +AV+ E PHELGD A+ ++SG+T KQA+ L +
Sbjct: 8 LHNFIDGISIGAAFAESLHSGLSISLAVLCEEFPHELGDVAILVASGMTLKQALIYNLLS 67
Query: 265 CLGSLTGAAIGCILNEMGKGNDELNNEEWTNKIMIITCGG-FIYTSTVGVVPEL 317
+ G IG + E+G T+K GG F+Y S ++PE+
Sbjct: 68 AITCYVGFFIGVGIGELGPD---------TSKYAFGLAGGMFLYISLACMMPEM 112
>CE12962 [U] KOG3907 ZIP-like zinc transporter proteins
Length = 381
Score = 57.4 bits (137), Expect = 3e-08
Identities = 39/143 (27%), Positives = 72/143 (50%), Gaps = 10/143 (6%)
Query: 180 TQSSRSKTNNKSLEVSTYLNMVTEFIHKAADGIAVSSSFYTSKY-VGIMSFMAVVFHEVP 238
T + + + +S + +V +H AADG+A+ S+ +K V I+ F+A++ H+ P
Sbjct: 194 TVARNDRAGRSRIGISATIGLV---VHAAADGVALGSASVINKSDVQIIVFVAIMLHKAP 250
Query: 239 HELGDFAVKLSSGLTFKQAIESEL--FTCLGSLTGAAIGCILNEMGKGNDELNNEEWTNK 296
G + L + ++AI L F+ L ++ +MG + + +E T
Sbjct: 251 AAFGLVSFLLMESID-RRAIRKHLVVFSAAAPLAALVTFVLIMQMG---ESMRSESSTGV 306
Query: 297 IMIITCGGFIYTSTVGVVPELLN 319
+M+ + G F+Y +TV V+PEL N
Sbjct: 307 LMLFSAGTFLYVATVHVLPELAN 329
>Hs8922968 [U] KOG3907 ZIP-like zinc transporter proteins
Length = 307
Score = 50.4 bits (119), Expect = 4e-06
Identities = 38/142 (26%), Positives = 69/142 (47%), Gaps = 12/142 (8%)
Query: 177 PTGTQSSRSKTNNKSLEVSTYLNMVTEFIHKAADGIAVSSSFYTSKY-VGIMSFMAVVFH 235
P +SS SK ++T L +V +H AADG+A+ ++ TS+ V ++ F+A++ H
Sbjct: 136 PEAARSSNSK-------ITTTLGLV---VHAAADGVALGAAASTSQTSVQLIVFVAIMLH 185
Query: 236 EVPHELGDFAVKLSSGLTFKQAIESELFTCLGSLTGAAIGCILNEMGKGNDELNNEEWTN 295
+ P G + + +GL + I L + ++ L + L+ T
Sbjct: 186 KAPAAFGLVSFLMHAGLE-RNRIRKHLLVFALAAPVTSMVTYLGLSKSSKEALSEVNATG 244
Query: 296 KIMIITCGGFIYTSTVGVVPEL 317
M+ + G F+Y +TV V+PE+
Sbjct: 245 VAMLFSAGTFLYVATVHVLPEV 266
>7304319 [U] KOG3907 ZIP-like zinc transporter proteins
Length = 283
Score = 50.1 bits (118), Expect = 5e-06
Identities = 44/142 (30%), Positives = 67/142 (46%), Gaps = 14/142 (9%)
Query: 183 SRSKTN---NKSLEVSTYLNMVTEFIHKAADGIAVSSSFYTSKY-VGIMSFMAVVFHEVP 238
S+ K+N NK + L +V +H AADG+A+ ++ TS V I+ F+A++ H+ P
Sbjct: 89 SQRKSNVGSNKKNNATLTLGLV---VHAAADGVALGAAATTSHQDVEIIVFLAIMLHKAP 145
Query: 239 HELGDFAVKLSSGLTFKQAIESELFTCLGSLTGAAIGCILNEMGKGN---DELNNEEWTN 295
G L + Q + L A + IL G G D LN+ T
Sbjct: 146 AAFGLVTFLLHEKVDRHQIRRHLVLFSLS----APLMTILTYFGIGQEQKDTLNSVNATG 201
Query: 296 KIMIITCGGFIYTSTVGVVPEL 317
M+ + G F+Y +TV V+PEL
Sbjct: 202 IAMLFSAGTFLYVATVHVLPEL 223
>CE28958 [P] KOG2693 Putative zinc transporter
Length = 466
Score = 49.3 bits (116), Expect = 8e-06
Identities = 43/167 (25%), Positives = 79/167 (46%), Gaps = 19/167 (11%)
Query: 191 SLEVST--YLNMVTEFIHKAADGIAVSSSFYTSKYVGIMSFMAVVFHEVPHELGDFAVKL 248
++EV++ Y+ + + DG+++ ++F + G+ +AV+ + P ELG A+ +
Sbjct: 302 AMEVASVAYMIIFGSSANNFVDGMSMGAAFSDNLLRGLSIGIAVISQQFPQELGTLAILV 361
Query: 249 SSGLTFKQAIESELFTCLGSLTGAAIGCILNEMGKGNDELNNEEWTNKIMIITCGGFIYT 308
SGL K+ + + + S G +IG +L+ + DE I I+ G ++Y
Sbjct: 362 KSGLGLKKTLLFNMVPIVLSFLGFSIGVMLDSVDDSYDEY--------IFAISSGMYMYI 413
Query: 309 STVGVVPELLNISTNSRRKE-----ITTTVIQIGCTLLG---FYMMS 347
++PE+ STN KE I +++Q L G Y MS
Sbjct: 414 FLGTLIPEIRE-STNELIKENLAESILVSILQACGILFGTTFMYFMS 459
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.322 0.139 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,022,851
Number of Sequences: 60738
Number of extensions: 717642
Number of successful extensions: 1760
Number of sequences better than 1.0e-05: 25
Number of HSP's better than 0.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 1687
Number of HSP's gapped (non-prelim): 42
length of query: 350
length of database: 30,389,216
effective HSP length: 107
effective length of query: 243
effective length of database: 23,890,250
effective search space: 5805330750
effective search space used: 5805330750
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)