ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI4706 good I KOG2112 Lipid transport and metabolism Lysophospholipase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI4706 1637803 1638486 228
(228 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YLR118c [I] KOG2112 Lysophospholipase 248 5e-66
Hs5453722 [I] KOG2112 Lysophospholipase 143 2e-34
CE27390 [I] KOG2112 Lysophospholipase 132 3e-31
Hs9966764 [I] KOG2112 Lysophospholipase 129 3e-30
SPAC8E11.04c [I] KOG2112 Lysophospholipase 126 2e-29
7294700_2 [I] KOG2112 Lysophospholipase 114 1e-25
At4g22300 [I] KOG2112 Lysophospholipase 105 5e-23
At5g20060 [I] KOG2112 Lysophospholipase 84 2e-16
At3g15650 [I] KOG2112 Lysophospholipase 78 9e-15
7299372 [I] KOG2112 Lysophospholipase 78 9e-15
Hs20270341 [I] KOG2112 Lysophospholipase 73 3e-13
At1g52700 [I] KOG2112 Lysophospholipase 70 3e-12
>YLR118c [I] KOG2112 Lysophospholipase
Length = 227
Score = 248 bits (633), Expect = 5e-66
Identities = 120/229 (52%), Positives = 162/229 (70%), Gaps = 9/229 (3%)
Query: 3 LNAVRVASKAQPAKNVILVFHGLGDSGSGWSFLAEYLQ-RSPA-FAHTRFVFPNAPNMRI 60
+N +RVA+K QPA+ I+ HGLGD+GSGW FLA+YLQ R PA F HT FVFPNAP + +
Sbjct: 1 MNGLRVAAKIQPARQTIIFLHGLGDTGSGWGFLAQYLQQRDPAAFQHTNFVFPNAPELHV 60
Query: 61 DANGGMSMPAWFNIYDWANPDARVDVEGIKSSLKVINSFIQEQIDDGISPENIILGGFSQ 120
ANGG MPAWF+I +W ++VD +G +SL I ++++ID GI PE II+GGFSQ
Sbjct: 61 TANGGALMPAWFDILEWDPSFSKVDSDGFMNSLNSIEKTVKQEIDKGIKPEQIIIGGFSQ 120
Query: 121 GAALTLASTVTSPYKLGGFFALSGFCRLK---KEDLDSIAENKNKDTPVFHGHGDQDPII 177
GAAL LA++VT P+K+GG ALSGFC + K+ + I N TP+FHGHGD DP++
Sbjct: 121 GAALALATSVTLPWKIGGIVALSGFCSIPGILKQHKNGI----NVKTPIFHGHGDMDPVV 176
Query: 178 PIQYGSDAKKFFEKYFHLSDYDFKSYRGMAHSTSLEEMQDLVQFLSKAL 226
PI G AK+F++ + +Y+FK Y+GMAHST +E++DL F+ K+L
Sbjct: 177 PIGLGIKAKQFYQDSCEIQNYEFKVYKGMAHSTVPDELEDLASFIKKSL 225
>Hs5453722 [I] KOG2112 Lysophospholipase
Length = 230
Score = 143 bits (360), Expect = 2e-34
Identities = 79/225 (35%), Positives = 128/225 (56%), Gaps = 7/225 (3%)
Query: 2 PLNAVRVASKAQPAKNVILVFHGLGDSGSGWSFLAEYLQRSPAFAHTRFVFPNAPNMRID 61
PL A+ A A+ A ++ HGLGD+G GW+ ++ S H +++ P+AP +
Sbjct: 9 PLPAIVPA--ARKATAAVIFLHGLGDTGHGWAEAFAGIRSS----HIKYICPHAPVRPVT 62
Query: 62 ANGGMSMPAWFNIYDWANPDARVDVEGIKSSLKVINSFIQEQIDDGISPENIILGGFSQG 121
N ++MP+WF+I +PD++ D GIK + + I + I +++ +GI IILGGFSQG
Sbjct: 63 LNMNVAMPSWFDIIG-LSPDSQEDESGIKQAAENIKALIDQEVKNGIPSNRIILGGFSQG 121
Query: 122 AALTLASTVTSPYKLGGFFALSGFCRLKKEDLDSIAENKNKDTPVFHGHGDQDPIIPIQY 181
AL+L + +T+ KL G ALS + L+ N+D + HGD DP++P+ +
Sbjct: 122 GALSLYTALTTQQKLAGVTALSCWLPLRASFPQGPIGGANRDISILQCHGDCDPLVPLMF 181
Query: 182 GSDAKKFFEKYFHLSDYDFKSYRGMAHSTSLEEMQDLVQFLSKAL 226
GS + + + ++ FK+Y GM HS+ +EM D+ QF+ K L
Sbjct: 182 GSLTVEKLKTLVNPANVTFKTYEGMMHSSCQQEMMDVKQFIDKLL 226
>CE27390 [I] KOG2112 Lysophospholipase
Length = 223
Score = 132 bits (333), Expect = 3e-31
Identities = 71/208 (34%), Positives = 116/208 (55%), Gaps = 8/208 (3%)
Query: 16 KNVILVFHGLGDSGSGWSFLAEYLQRSPAFAHTRFVFPNAPNMRIDANGGMSMPAWFNIY 75
K ++ HGLGD G GW A+ + + +F+ P++ + N GM MPAWF+++
Sbjct: 19 KGTLIFLHGLGDQGHGW---ADAFKTEAKHDNIKFICPHSSERPVTLNMGMRMPAWFDLF 75
Query: 76 DWANPDARVDVEGIKSSLKVINSFIQEQIDDGISPENIILGGFSQGAALTLASTVTSPYK 135
+P+A+ D +GI + + ++ I ++ GI I +GGFS G AL + + +T P K
Sbjct: 76 G-LDPNAQEDEQGINRATQYVHQLIDAEVAAGIPASRIAVGGFSMGGALAIYAGLTYPQK 134
Query: 136 LGGFFALSGFCRLKKEDLDSIAENKNKDTPVFHGHGDQDPIIPIQYGSDAKKFFEKYFHL 195
LGG LS F + + S N TP+F GHG D ++P+Q+G ++++ +K+
Sbjct: 135 LGGIVGLSSFFLQRTKFPGSF--TANNATPIFLGHGTDDFLVPLQFGQMSEQYIKKF--N 190
Query: 196 SDYDFKSYRGMAHSTSLEEMQDLVQFLS 223
+ +YRGM HS+ EEM+D+ FLS
Sbjct: 191 PKVELHTYRGMQHSSCGEEMRDVKTFLS 218
>Hs9966764 [I] KOG2112 Lysophospholipase
Length = 231
Score = 129 bits (324), Expect = 3e-30
Identities = 71/224 (31%), Positives = 118/224 (51%), Gaps = 6/224 (2%)
Query: 3 LNAVRVASKAQPAKNVILVFHGLGDSGSGWSFLAEYLQRSPAFAHTRFVFPNAPNMRIDA 62
L S A+ ++ HGLGD+G W+ ++ H +++ P+AP + +
Sbjct: 11 LTDAATVSGAERETAAVIFLHGLGDTGHSWADALSTIR----LPHVKYICPHAPRIPVTL 66
Query: 63 NGGMSMPAWFNIYDWANPDARVDVEGIKSSLKVINSFIQEQIDDGISPENIILGGFSQGA 122
N M MP+WF++ +PDA D GIK + + I + I+ ++ +GI I+LGGFSQG
Sbjct: 67 NMKMVMPSWFDLMG-LSPDAPEDEAGIKKAAENIKALIEHEMKNGIPANRIVLGGFSQGG 125
Query: 123 ALTLASTVTSPYKLGGFFALSGFCRLKKEDLDSIAENKNKDTPVFHGHGDQDPIIPIQYG 182
AL+L + +T P+ L G ALS + L + A KD + HG+ DP++P+++G
Sbjct: 126 ALSLYTALTCPHPLAGIVALSCWLPLHRA-FPQAANGSAKDLAILQCHGELDPMVPVRFG 184
Query: 183 SDAKKFFEKYFHLSDYDFKSYRGMAHSTSLEEMQDLVQFLSKAL 226
+ + + FK+Y G+ HS+ +EM + +FL K L
Sbjct: 185 ALTAEKLRSVVTPARVQFKTYPGVMHSSCPQEMAAVKEFLEKLL 228
>SPAC8E11.04c [I] KOG2112 Lysophospholipase
Length = 224
Score = 126 bits (317), Expect = 2e-29
Identities = 76/219 (34%), Positives = 114/219 (51%), Gaps = 7/219 (3%)
Query: 3 LNAVRVASKAQPAKNVILVFHGLGDSGSGWSFLAEYLQRSPAFAHTRFVFPNAPNMRIDA 62
LN+V + VI + HGLGDSG GWSF+A F H +++FPNAP++ +
Sbjct: 5 LNSVIINPSVAHTATVIFL-HGLGDSGQGWSFMANTWSN---FKHIKWIFPNAPSIPVTV 60
Query: 63 NGGMSMPAWFNIYDWANPDARVDVEGIKSSLKVINSFIQEQIDDGISPENIILGGFSQGA 122
N GM MPAW++IY +A+ R D GI S ++ I ++ GI + I++GGFSQG
Sbjct: 61 NNGMKMPAWYDIYSFADM-KREDENGILRSAGQLHELIDAELALGIPSDRILIGGFSQGC 119
Query: 123 ALTLASTVTSPYKLGGFFALSGFCRLKKEDLDSIAENKNKDTPVFHGHGDQDPIIPIQYG 182
++L + +T P +L G SGF L + S K+ P+ + +DPI+P
Sbjct: 120 MVSLYAGLTYPKRLAGIMGHSGFLPLASK-FPSALSRVAKEIPILLTYMTEDPIVPSVLS 178
Query: 183 SDAKKFFEKYFHLSDYDFKSYRGMAHSTSLEEMQDLVQF 221
S + K+ L D + + G AHS S E + +F
Sbjct: 179 SASAKYLINNLQLKCLD-RPFEGDAHSLSSESFMAMYKF 216
>7294700_2 [I] KOG2112 Lysophospholipase
Length = 211
Score = 114 bits (284), Expect = 1e-25
Identities = 67/192 (34%), Positives = 104/192 (53%), Gaps = 13/192 (6%)
Query: 29 GSGWSFLAEYLQRSPAFAHTRFVFPNAPNMRIDANGGMSMPAWFNI--YDWANPDARVDV 86
G GWS ++ P F + + P AP + N G MP+WF++ D P+ D
Sbjct: 1 GHGWSSALAAIR--PPFM--KVICPTAPTQPVSLNAGFRMPSWFDLKTLDIGGPE---DE 53
Query: 87 EGIKSSLKVINSFIQEQIDDGISPENIILGGFSQGAALTLASTVTSPYKLGGFFALSGFC 146
GI+S+ ++ IQ++I GI I+LGGFSQG AL L S +T L G ALS +
Sbjct: 54 PGIQSARDSVHGMIQKEISAGIPANRIVLGGFSQGGALALYSALTYDQPLAGVVALSCWL 113
Query: 147 RLKKEDLDSIAENKNKDTPVFHGHGDQDPIIPIQYGSDAKKFFEKYFHLSDYDFKSYRGM 206
L K+ A+ + D P+F HGD DP++P ++G + + + + + FK+Y G+
Sbjct: 114 PLHKQFPG--AKVNSDDVPIFQAHGDYDPVVPYKFGQLSASLLKSF--MKNVTFKTYSGL 169
Query: 207 AHSTSLEEMQDL 218
+HS+S +EM D+
Sbjct: 170 SHSSSDDEMDDV 181
>At4g22300 [I] KOG2112 Lysophospholipase
Length = 471
Score = 105 bits (262), Expect = 5e-23
Identities = 65/222 (29%), Positives = 112/222 (50%), Gaps = 12/222 (5%)
Query: 15 AKNVILVFHGLGDSGSGWSFLAEYLQRSPAFAHTRFVFPNAPNMRIDANGGMSMPAWFNI 74
A+ IL HGLGDSG + +S ++ ++FP+AP + N G M +WF++
Sbjct: 2 ARTFILWLHGLGDSGPANEPIQTQF-KSSELSNASWLFPSAPFNPVTCNNGAVMRSWFDV 60
Query: 75 YDWA-NPDARVDVEGIKSSLKVINSFIQEQIDDGISPENIILGGFSQGAALTLASTVTSP 133
+ + +D + ++K +++ I ++I +G +PEN+ + G SQG ALTLAS + P
Sbjct: 61 PELPFKVGSPIDESSVLEAVKNVHAIIDQEIAEGTNPENVFICGLSQGGALTLASVLLYP 120
Query: 134 YKLGGFFALSGFCRLKKEDLDSIAENKNK--------DTPVFHGHGDQDPIIPIQYGSDA 185
LGG LSG+ + E K +TP+ HG D ++ + G A
Sbjct: 121 KTLGGGAVLSGWVPFTSSIISQFPEEAKKVPHLCFLINTPILWSHGTDDRMVLFEAGQAA 180
Query: 186 KKFFEKYFHLSDYDFKSYRGMAHSTSLEEMQDLVQFLSKALK 227
F ++ +FK+Y G+ HS S +E++ + ++ + LK
Sbjct: 181 LPFLKEAG--VTCEFKAYPGLGHSISNKELKYIESWIKRRLK 220
Score = 102 bits (254), Expect = 4e-22
Identities = 61/178 (34%), Positives = 95/178 (53%), Gaps = 3/178 (1%)
Query: 15 AKNVILVFHGLGDSGSGWSFLAEYLQRSPAFAHTRFVFPNAPNMRIDANGGMSMPAWFNI 74
A+ IL HGLGDSG + + L RS F +T+++FP+AP + N G MP+WF+I
Sbjct: 287 ARTFILWLHGLGDSGPANEPI-KTLFRSQEFRNTKWLFPSAPPNPVSCNYGAVMPSWFDI 345
Query: 75 YDWA-NPDARVDVEGIKSSLKVINSFIQEQIDDGISPENIILGGFSQGAALTLASTVTSP 133
+ + D + ++K +++ I ++I GI+PEN+ + GFSQG ALTLAS + P
Sbjct: 346 PELPLTAGSPKDESSLLKAVKNVHAIIDKEIAGGINPENVYICGFSQGGALTLASVLLYP 405
Query: 134 YKLGGFFALSGFCRLKKEDLDSIAENKNKDTPVFHGHGDQDPIIPIQYGSDAKKFFEK 191
+GG SG+ + E+ K TP+ HG D + + G A F ++
Sbjct: 406 KTIGGGAVFSGWIPFNSSITNQFTEDAKK-TPILWSHGIDDKTVLFEAGQAALPFLQQ 462
>At5g20060 [I] KOG2112 Lysophospholipase
Length = 252
Score = 84.0 bits (206), Expect = 2e-16
Identities = 65/226 (28%), Positives = 97/226 (42%), Gaps = 27/226 (11%)
Query: 19 ILVFHGLGDSGSGWSFLAEYLQRSPAFAHTRFVFPNAPNMRIDANGGMSMPAWFNIYDWA 78
I+ HGLGD+GS WS L E L + +++ P AP+ I GG AWF++ D
Sbjct: 36 IVWLHGLGDNGSSWSQLLETL----PLPNIKWICPTAPSQPISLFGGFPSTAWFDVVD-I 90
Query: 79 NPDARVDVEGIK-SSLKVINSFIQEQIDDGISPENIILGGFSQGAALTLASTV------- 130
N D D+EG+ ++ V N E D + +GGFS GAA +L S
Sbjct: 91 NEDGPDDMEGLDVAAAHVANLLSNEPADIKLG-----VGGFSMGAATSLYSATCFALGKY 145
Query: 131 ----TSPYKLGGFFALSGFCRLKKEDLDSIAE----NKNKDTPVFHGHGDQDPIIPIQYG 182
P L LSG+ K + E N+ P+ HG D ++P ++G
Sbjct: 146 GNGNPYPINLSAIIGLSGWLPCAKTLAGKLEEEQIKNRAASLPIVVCHGKADDVVPFKFG 205
Query: 183 SDAKKFFEKYFHLSDYDFKSYRGMAHSTSLEEMQDLVQFLSKALKL 228
+ + FK Y + H T +E+ +L +L+ L L
Sbjct: 206 EKSSQALLSN-GFKKVTFKPYSALGHHTIPQELDELCAWLTSTLSL 250
>At3g15650 [I] KOG2112 Lysophospholipase
Length = 255
Score = 78.2 bits (191), Expect = 9e-15
Identities = 68/235 (28%), Positives = 104/235 (43%), Gaps = 44/235 (18%)
Query: 19 ILVFHGLGDSGSGWSFLAEYLQRSPAFAHTRFVFPNAPNMRIDANGGMSMPAWFNIYDWA 78
I+ HGLGD+GS S L E L + +++ P AP+ + GG AWF++ +
Sbjct: 36 IVWLHGLGDNGSSSSQLLESLP----LPNIKWICPTAPSRPVSLLGGFPCTAWFDVGE-I 90
Query: 79 NPDARVDVEGIKSSLKVINSFIQEQIDDGISPENIILGGFSQGAALTLASTVTSPYKLGG 138
+ D D+EG+ +S I + + + D + +GGFS GAA+ L ST Y LG
Sbjct: 91 SEDLHDDIEGLDASAAHIANLLSAEPTD----VKVGIGGFSMGAAIALYSTTC--YALGR 144
Query: 139 F-------------FALSGFC------RLKKEDLDSIAENKNKDTPVFHGHGDQDPIIPI 179
+ LSG+ R K E + +A + P+ HG D ++P
Sbjct: 145 YGTGHAYTINLRATVGLSGWLPGWRSLRSKIESSNEVAR-RAASIPILLAHGTSDDVVPY 203
Query: 180 QYGSDAKKFFEKYFH------LSDYDFKSYRGMAHSTSLEEMQDLVQFLSKALKL 228
++G EK H FK Y G+ H T +EM ++V +L L L
Sbjct: 204 RFG-------EKSAHSLAMAGFRQTMFKPYEGLGHYTVPKEMDEVVHWLVSRLGL 251
>7299372 [I] KOG2112 Lysophospholipase
Length = 235
Score = 78.2 bits (191), Expect = 9e-15
Identities = 57/211 (27%), Positives = 89/211 (42%), Gaps = 7/211 (3%)
Query: 19 ILVFHGLGDSGSGWSFLAEYL-QRSPAFAHTRFVFPNAPNMRIDANGGMSMPAWFNIYDW 77
++ FHG GD+G +L R+ + H + ++P AP + G WF+
Sbjct: 18 VIFFHGSGDTGPNVLEWVRFLIGRNLEYPHIKIIYPTAPKQKYTPLDGELSNVWFDRKS- 76
Query: 78 ANPDARVDVEGIKSSLKVINSFIQEQIDDGISPENIILGGFSQGAALTLASTVTSPYKLG 137
N A + + +N I E++ GI I++GGFS G AL L + L
Sbjct: 77 VNIAASESKKSMSQCYDAVNQLIDEEVASGIPLNRIVVGGFSMGGALALHTGYHLRRSLA 136
Query: 138 GFFALSGFCRLKKEDLDSIAENKNKDTPVFH-GHGDQDPIIPIQYGSDAKKFFEKYFHLS 196
G FA S F DS+A K++ P HG++D ++P +G + FE L
Sbjct: 137 GVFAHSSFLNRGSVVYDSLANGKDESFPELRMYHGERDTLVPKDWGLET---FENLTKLG 193
Query: 197 -DYDFKSYRGMAHSTSLEEMQDLVQFLSKAL 226
F R H + DL Q++ + L
Sbjct: 194 VKGTFHPLRNTLHELKTASITDLQQWIYEKL 224
>Hs20270341 [I] KOG2112 Lysophospholipase
Length = 237
Score = 73.2 bits (178), Expect = 3e-13
Identities = 47/201 (23%), Positives = 83/201 (40%), Gaps = 4/201 (1%)
Query: 19 ILVFHGLGDSGSGWS-FLAEYLQRSPAFAHTRFVFPNAPNMRIDANGGMSMPAWFNIYDW 77
++ HG GDSG G ++ + L + F H + ++P AP G WF+ +
Sbjct: 24 LIFLHGSGDSGQGLRMWIKQVLNQDLTFQHIKIIYPTAPPRSYTPMKGGISNVWFDRFKI 83
Query: 78 ANPDARVDVEGIKSSLKVINSFIQEQIDDGISPENIILGGFSQGAALTLASTVTSPYKLG 137
N D +E I +V+ I E++ GI I++GGFS G + + + +
Sbjct: 84 TN-DCPEHLESIDVMCQVLTDLIDEEVKSGIKKNRILIGGFSMGGCMAMHLAYRNHQDVA 142
Query: 138 GFFALSGFCRLKKEDLDSIAENKNKDTPVFHGHGDQDPIIPIQYGSDAKKFFEKYFHLSD 197
G FALS F ++ ++ +F HG D ++ + + + +
Sbjct: 143 GVFALSSFLNKASAVYQALQKSNGVLPELFQCHGTADELVLHSWAEETNSMLKSLGVTT- 201
Query: 198 YDFKSYRGMAHSTSLEEMQDL 218
F S+ + H S E+ L
Sbjct: 202 -KFHSFPNVYHELSKTELDIL 221
>At1g52700 [I] KOG2112 Lysophospholipase
Length = 223
Score = 69.7 bits (169), Expect = 3e-12
Identities = 58/207 (28%), Positives = 98/207 (47%), Gaps = 28/207 (13%)
Query: 23 HGLGDSGSGWSFLAEYLQRSPAFAHTRFVFPNAPNMRIDANGGMSMPAWFNIYDWANPDA 82
HGLGD+GS S L + L + +++ P AP+ + + GG + AWF++ + + D
Sbjct: 40 HGLGDNGSSSSQLMDSLH----LPNIKWICPTAPSRPVTSLGGFTCTAWFDVGE-ISEDG 94
Query: 83 RVDVEGIKSSLKVINSFIQEQIDDGISPENIILGGFSQGAALTLASTVTSPYKLGGFFAL 142
D+EG+ +S I + + + P ++ +GGFS GAA++L S Y LG +
Sbjct: 95 HDDLEGLDASASHIANLLSSE------PADVGIGGFSMGAAISLYSATC--YALGRY--- 143
Query: 143 SGFCRLKKEDLDSIAENKNKDTPVFHGHGDQDPIIPIQYGS-DAKKFFEKYFHLSDYDFK 201
G +L ++ G D ++P ++G A+ F L+ FK
Sbjct: 144 -GTGHAYPINLQAVVG--------LSGWLPADDVVPYRFGEKSAQSLGMAGFRLAM--FK 192
Query: 202 SYRGMAHSTSLEEMQDLVQFLSKALKL 228
Y G+ H T EM ++V +L+ L L
Sbjct: 193 PYEGLGHYTVPREMDEVVHWLTTMLGL 219
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.319 0.137 0.409
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,095,302
Number of Sequences: 60738
Number of extensions: 617292
Number of successful extensions: 1411
Number of sequences better than 1.0e-05: 12
Number of HSP's better than 0.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 1363
Number of HSP's gapped (non-prelim): 13
length of query: 228
length of database: 30,389,216
effective HSP length: 103
effective length of query: 125
effective length of database: 24,133,202
effective search space: 3016650250
effective search space used: 3016650250
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)