ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI4730 check: MH A KOG0119 RNA processing and modification Splicing factor 1/branch point binding protein (RRM superfamily)
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI4730 1649127 1647751 -459
(459 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YLR116w [A] KOG0119 Splicing factor 1/branch point binding prote... 316 4e-86
SPCC962.06c [A] KOG0119 Splicing factor 1/branch point binding p... 225 9e-59
Hs4759340 [A] KOG0119 Splicing factor 1/branch point binding pro... 186 6e-47
7300268 [A] KOG0119 Splicing factor 1/branch point binding prote... 186 6e-47
CE28108 [A] KOG0119 Splicing factor 1/branch point binding prote... 171 3e-42
At5g51300 [A] KOG0119 Splicing factor 1/branch point binding pro... 129 7e-30
Hs22058283 [A] KOG1588 RNA-binding protein Sam68 and related KH ... 108 2e-23
CE13896 [A] KOG1588 RNA-binding protein Sam68 and related KH dom... 108 2e-23
CE14096 [A] KOG1588 RNA-binding protein Sam68 and related KH dom... 104 2e-22
7300809 [A] KOG1588 RNA-binding protein Sam68 and related KH dom... 100 8e-21
At3g08620 [A] KOG1588 RNA-binding protein Sam68 and related KH d... 94 3e-19
At5g56140 [A] KOG1588 RNA-binding protein Sam68 and related KH d... 91 3e-18
At2g38610 [A] KOG1588 RNA-binding protein Sam68 and related KH d... 89 1e-17
At4g26480_2 [A] KOG1588 RNA-binding protein Sam68 and related KH... 89 1e-17
At1g09660 [A] KOG1588 RNA-binding protein Sam68 and related KH d... 85 2e-16
Hs20553511 [A] KOG1588 RNA-binding protein Sam68 and related KH ... 81 3e-15
CE27520 [A] KOG1588 RNA-binding protein Sam68 and related KH dom... 80 5e-15
Hs5730027 [A] KOG1588 RNA-binding protein Sam68 and related KH d... 78 2e-14
CE18029 [A] KOG1588 RNA-binding protein Sam68 and related KH dom... 77 5e-14
Hs5730073 [A] KOG1588 RNA-binding protein Sam68 and related KH d... 74 3e-13
7302782 [A] KOG1588 RNA-binding protein Sam68 and related KH dom... 69 1e-11
7291417 [A] KOG1588 RNA-binding protein Sam68 and related KH dom... 69 1e-11
7291415 [A] KOG1588 RNA-binding protein Sam68 and related KH dom... 69 1e-11
7291333 [A] KOG1588 RNA-binding protein Sam68 and related KH dom... 69 2e-11
7291423 [A] KOG1588 RNA-binding protein Sam68 and related KH dom... 68 2e-11
7291433 [A] KOG1588 RNA-binding protein Sam68 and related KH dom... 67 4e-11
7291418 [A] KOG1588 RNA-binding protein Sam68 and related KH dom... 66 9e-11
CE29534_2 [A] KOG1588 RNA-binding protein Sam68 and related KH d... 61 3e-09
ECU02g1160 [A] KOG0119 Splicing factor 1/branch point binding pr... 59 1e-08
CE05936 [A] KOG1588 RNA-binding protein Sam68 and related KH dom... 57 6e-08
CE08610 [A] KOG1588 RNA-binding protein Sam68 and related KH dom... 53 8e-07
At3g32940 [A] KOG0119 Splicing factor 1/branch point binding pro... 50 7e-06
>YLR116w [A] KOG0119 Splicing factor 1/branch point binding protein (RRM
superfamily)
Length = 476
Score = 316 bits (810), Expect = 4e-86
Identities = 156/238 (65%), Positives = 185/238 (77%)
Query: 12 ALWGAKARENAVFEQIGLPAVINGFLAPEHETAYQVMFRIAEITAKLRSNDLTXXXXXXX 71
+LW E+ V LP+ I+G L E +YQVMFRI EIT KLR+ND
Sbjct: 33 SLWRKNTVESDVHRFNSLPSKISGALTREQIYSYQVMFRIQEITIKLRTNDFVPPSRKNR 92
Query: 72 XXXXXXVYDARGRRTNTKEQRYKRKLEEERHRLVEIALKMIPNFVTPDDYRRPTRFQDKY 131
VYDA+G+RTNT+EQRY++KLE+ER +LVEIALK IP FV PDDY+RPT+FQDKY
Sbjct: 93 SPSPPPVYDAQGKRTNTREQRYRKKLEDERIKLVEIALKTIPYFVPPDDYKRPTKFQDKY 152
Query: 132 YIPTEDYPDINFVGLLLGPRGNTLKKLQQESGCKISIRGRGSVRSGKAAADLPKGAMNMN 191
YIP + YPD+NFVGLLLGPRG TL+KLQ++S CKI+IRGRGSV+ GK A+DLP GAMN
Sbjct: 153 YIPVDQYPDVNFVGLLLGPRGRTLRKLQEDSNCKIAIRGRGSVKEGKNASDLPPGAMNFE 212
Query: 192 EPLHCIIIADVEDKIPLGIKACESIVVKAITSPEGQNDLKRGQLRELAVLNGTLREDN 249
+PLHC+IIAD EDKI GIK C++IV+KA+TSPEGQNDLKRGQLRELA LNGTLREDN
Sbjct: 213 DPLHCLIIADSEDKIQKGIKVCQNIVIKAVTSPEGQNDLKRGQLRELAELNGTLREDN 270
>SPCC962.06c [A] KOG0119 Splicing factor 1/branch point binding protein (RRM
superfamily)
Length = 587
Score = 225 bits (574), Expect = 9e-59
Identities = 113/229 (49%), Positives = 152/229 (66%), Gaps = 2/229 (0%)
Query: 20 ENAVFEQIGLPAVINGFLAPEHETAYQVMFRIAEITAKLRSNDLTXXXXXXXXXXXXXVY 79
E + Q+ L + + E Y + R+ EIT KLR+ D+ Y
Sbjct: 80 EEMLPSQMELETAVKSCMTMEQLELYSLNVRLEEITQKLRTGDVVPHHRERSPSPPPQ-Y 138
Query: 80 DARGRRTNTKEQRYKRKLEEERHRLVEIALKMIPNFVTPDDYRRPTRFQDKYYIPTEDYP 139
D GRR NT+E RYK+KLE+ERHR++E A+KM+P F P DYRRP + Q+K Y+P +DYP
Sbjct: 139 DNHGRRLNTREIRYKKKLEDERHRIIERAMKMVPGFRAPSDYRRPAKTQEKVYVPVKDYP 198
Query: 140 DINFVGLLLGPRGNTLKKLQQESGCKISIRGRGSVRSGKAAADLPKGAMNMNEPLHCIII 199
+INF+GLL+GPRG+TLK ++ +SG KI+IRG+GSV+ GK +D P NM E LHC++
Sbjct: 199 EINFIGLLIGPRGHTLKDMEAKSGAKIAIRGKGSVKEGKGRSD-PSVRGNMEEDLHCLVT 257
Query: 200 ADVEDKIPLGIKACESIVVKAITSPEGQNDLKRGQLRELAVLNGTLRED 248
AD EDKI IK ++++ A + PEGQNDLKR QLR+LA LNGTLR+D
Sbjct: 258 ADSEDKINHAIKLIDNVIQTAASVPEGQNDLKRNQLRQLATLNGTLRDD 306
>Hs4759340 [A] KOG0119 Splicing factor 1/branch point binding protein (RRM
superfamily)
Length = 623
Score = 186 bits (472), Expect = 6e-47
Identities = 99/224 (44%), Positives = 141/224 (62%), Gaps = 2/224 (0%)
Query: 28 GLPAVINGFLAPEHETAYQVMFRIAEITAKLRSNDLTXXXXXXXXXXXXX-VYDARGRRT 86
G+P VI L E E AY V +I ++T KLR+ DL +Y++ G+R
Sbjct: 35 GMPTVIPPGLTREQERAYIVQLQIEDLTRKLRTGDLGIPPNPEDRSPSPEPIYNSEGKRL 94
Query: 87 NTKEQRYKRKLEEERHRLVEIALKMIPNFVTPDDYRRP-TRFQDKYYIPTEDYPDINFVG 145
NT+E R ++KLEEERH L+ + + P+F P DY+ P TR DK IP ++YP+INFVG
Sbjct: 95 NTREFRTRKKLEEERHNLITEMVALNPDFKPPADYKPPATRVSDKVMIPQDEYPEINFVG 154
Query: 146 LLLGPRGNTLKKLQQESGCKISIRGRGSVRSGKAAADLPKGAMNMNEPLHCIIIADVEDK 205
LL+GPRGNTLK +++E KI IRG+GSV+ GK + +EPLH ++ A+ +
Sbjct: 155 LLIGPRGNTLKNIEKECNAKIMIRGKGSVKEGKVGRKDGQMLPGEDEPLHALVTANTMEN 214
Query: 206 IPLGIKACESIVVKAITSPEGQNDLKRGQLRELAVLNGTLREDN 249
+ ++ +I+ + I +PE QNDL++ QLRELA LNGTLRED+
Sbjct: 215 VKKAVEQIRNILKQGIETPEDQNDLRKMQLRELARLNGTLREDD 258
>7300268 [A] KOG0119 Splicing factor 1/branch point binding protein (RRM
superfamily)
Length = 663
Score = 186 bits (472), Expect = 6e-47
Identities = 100/238 (42%), Positives = 141/238 (59%), Gaps = 4/238 (1%)
Query: 14 WGAKARENAVFEQIGLPAVINGFLAPEHETAYQVMFRIAEITAKLRSNDLTXXXXXXXXX 73
WG + G+P ++ L P + AY V F+I EI+ KLR+ DL
Sbjct: 278 WGGSENDKTFIP--GMPTILPSTLDPAQQEAYLVQFQIEEISRKLRTGDLGITQNPEERS 335
Query: 74 XXXX-VYDARGRRTNTKEQRYKRKLEEERHRLVEIALKMIPNFVTPDDYRRP-TRFQDKY 131
+Y + G+R NT+E RY+++LEE+RH+L+ + P F P DY+ P TR DK
Sbjct: 336 PSPEPIYSSDGKRLNTREFRYRKRLEEQRHQLIVKMQTVNPEFKPPADYKPPVTRVSDKV 395
Query: 132 YIPTEDYPDINFVGLLLGPRGNTLKKLQQESGCKISIRGRGSVRSGKAAADLPKGAMNMN 191
IP E +PDINFVGLL+GPRGNTLK +++++G KI IRG+GSV+ GK + +
Sbjct: 396 LIPQEQHPDINFVGLLIGPRGNTLKAMEKDTGAKIIIRGKGSVKEGKVGRKDGQPLPGED 455
Query: 192 EPLHCIIIADVEDKIPLGIKACESIVVKAITSPEGQNDLKRGQLRELAVLNGTLREDN 249
EPLH I A + + + + ++ + I PEG NDL+R QLRELA LNGTLRE++
Sbjct: 456 EPLHAFITAPNPEAVRKAVDKIKDVIRQGIEVPEGHNDLRRMQLRELAQLNGTLREND 513
>CE28108 [A] KOG0119 Splicing factor 1/branch point binding protein (RRM
superfamily)
Length = 699
Score = 171 bits (432), Expect = 3e-42
Identities = 98/226 (43%), Positives = 132/226 (58%), Gaps = 9/226 (3%)
Query: 28 GLPAVINGFLAPEHETAYQVMFRIAEITAKLRSNDLTXXXXXXXXXXXXXVYDARGRRTN 87
G+P ++ L + AY + I + T KLR D VYDA G+R N
Sbjct: 203 GMPTILPADLTEDQRNAYLLQLEIEDATRKLRLADFGVAEGRERSPSPEPVYDANGKRLN 262
Query: 88 TKEQRYKRKLEEERHRLVEIALKMIPNFVTPDDYRRPT-RFQDKYYIPTEDYPDINFVGL 146
T+E R +++LE+ RH ++ LK+ PNF P DYR P R DK +IP E +PD+NFVGL
Sbjct: 263 TREVRKRQELEQLRHEKIQALLKINPNFKPPADYRAPNIRLHDKVWIPQEQFPDLNFVGL 322
Query: 147 LLGPRGNTLKKLQQESGCKISIRGRGSVRSGKAAADLPKGAM-NMNEPLHCIIIADVEDK 205
L+GPRGNTLK L+ E+G KI IRG+GS++ GK L G M NEPLH + +
Sbjct: 323 LIGPRGNTLKSLEAETGAKIIIRGKGSIKEGKLTNRL--GPMPGENEPLHAYVTGTDMNV 380
Query: 206 IPLGIKACESI--VVKAITSPEGQNDLKRGQLRELAVLNGTLREDN 249
I KACE I V+ T+ N+L++ QLRELA+LNGT R ++
Sbjct: 381 IK---KACEKIKQVIAEATALPDNNELRKLQLRELALLNGTFRPED 423
>At5g51300 [A] KOG0119 Splicing factor 1/branch point binding protein (RRM
superfamily)
Length = 804
Score = 129 bits (325), Expect = 7e-30
Identities = 73/181 (40%), Positives = 111/181 (60%), Gaps = 9/181 (4%)
Query: 78 VYDARGRRTNTKEQRYKRKLEEERHRLVEIALKMIPNFVTPDDYRRPTRFQDKYYIPTED 137
VYD G R NT+E R + +L ER ++ +K P F P DYR P + K +IP ++
Sbjct: 193 VYDNMGIRINTREYRARERLNRERQEIIAQIIKKNPAFKPPADYR-PPKLHKKLFIPMKE 251
Query: 138 YPDINFVGLLLGPRGNTLKKLQQESGCKISIRGRGSVRSGK--AAADLPKGAMNMNEPLH 195
+P NF+GL++GPRGNT K++++E+G KI IRG+GSV+ G+ DL K + NE LH
Sbjct: 252 FPGYNFIGLIIGPRGNTQKRMERETGAKIVIRGKGSVKEGRHQQKKDL-KYDPSENEDLH 310
Query: 196 CIIIADVEDKIPLGIKACESIVVKAITS-PEGQNDLKRGQLRELAVLNGTLREDNYVQTF 254
++ A+ ++ ++A +V K + E N+ KR QLRELA LNGT+R++ + +
Sbjct: 311 VLVEAETQE----ALEAAAGMVEKLLQPVDEVLNEHKRQQLRELATLNGTIRDEEFCRLC 366
Query: 255 G 255
G
Sbjct: 367 G 367
>Hs22058283 [A] KOG1588 RNA-binding protein Sam68 and related KH domain
proteins
Length = 341
Score = 108 bits (269), Expect = 2e-23
Identities = 58/137 (42%), Positives = 88/137 (63%), Gaps = 6/137 (4%)
Query: 118 PDDYRRPTRFQDKYYIPTEDYPDINFVGLLLGPRGNTLKKLQQESGCKISIRGRGSVRSG 177
PD + Q+K Y+P ++YPD NFVG +LGPRG T K+L+ E+GCKI +RG+GS+R
Sbjct: 73 PDAVGPIVQLQEKLYVPVKEYPDFNFVGRILGPRGLTAKQLEAETGCKIMVRGKGSMRD- 131
Query: 178 KAAADLPKGAMN---MNEPLHCII-IADVEDKIPLGIK-ACESIVVKAITSPEGQNDLKR 232
K + +G N +NE LH +I + D +++ + +K A E + + + EG++ LK+
Sbjct: 132 KKKEEQNRGKPNWEHLNEDLHVLITVEDAQNRAEIKLKRAVEEVKKLLVPAAEGEDSLKK 191
Query: 233 GQLRELAVLNGTLREDN 249
QL ELA+LNGT R+ N
Sbjct: 192 MQLMELAILNGTYRDAN 208
>CE13896 [A] KOG1588 RNA-binding protein Sam68 and related KH domain
proteins
Length = 403
Score = 108 bits (269), Expect = 2e-23
Identities = 59/134 (44%), Positives = 88/134 (65%), Gaps = 6/134 (4%)
Query: 118 PDDYRRPTRFQDKYYIPTEDYPDINFVGLLLGPRGNTLKKLQQESGCKISIRGRGSVRSG 177
PD T +K ++P +++PD NFVG +LGPRG T K+L+QE+GCKI +RGRGS+R
Sbjct: 79 PDAEGDSTVHTEKVFVPAKEHPDYNFVGRILGPRGMTAKQLEQETGCKIMVRGRGSMRD- 137
Query: 178 KAAADLPKGAMN---MNEPLHCII-IADVEDKIPLGI-KACESIVVKAITSPEGQNDLKR 232
K +L +G N ++E LH +I D E++ + + +A E + + +PEG++DLKR
Sbjct: 138 KKKEELNRGKPNWEHLSEELHVLIQCEDTENRAKVKLMRAVEEVRKLLVPAPEGEDDLKR 197
Query: 233 GQLRELAVLNGTLR 246
QL ELA++NGT R
Sbjct: 198 KQLMELAIINGTYR 211
>CE14096 [A] KOG1588 RNA-binding protein Sam68 and related KH domain
proteins
Length = 463
Score = 104 bits (260), Expect = 2e-22
Identities = 60/159 (37%), Positives = 95/159 (59%), Gaps = 7/159 (4%)
Query: 94 KRKLEEERHRL-VEIALKMIPNFVTPDDYRRPTRFQDKYYIPTEDYPDINFVGLLLGPRG 152
+R L++E R+ V + P P+ +K Y+P +YPD NFVG +LGPRG
Sbjct: 171 ERLLDDEIGRVRVALFQTEFPRVELPEPAGDMISITEKIYVPKNEYPDYNFVGRILGPRG 230
Query: 153 NTLKKLQQESGCKISIRGRGSVRSGKAAADLPKGAMN---MNEPLHCII-IADVEDKIPL 208
T K+L+Q++GCKI +RG+GS+R K+ +G N + + LH ++ D E+++ +
Sbjct: 231 MTAKQLEQDTGCKIMVRGKGSMRD-KSKESAHRGKANWEHLEDDLHVLVQCEDTENRVHI 289
Query: 209 GIKAC-ESIVVKAITSPEGQNDLKRGQLRELAVLNGTLR 246
++A E + I +PEG ++LKR QL ELA++NGT R
Sbjct: 290 KLQAALEQVKKLLIPAPEGTDELKRKQLMELAIINGTYR 328
>7300809 [A] KOG1588 RNA-binding protein Sam68 and related KH domain
proteins
Length = 405
Score = 99.8 bits (247), Expect = 8e-21
Identities = 52/124 (41%), Positives = 82/124 (65%), Gaps = 6/124 (4%)
Query: 129 DKYYIPTEDYPDINFVGLLLGPRGNTLKKLQQESGCKISIRGRGSVRSGKAAADLPKGAM 188
+K Y+P ++PD NFVG +LGPRG T K+L+QE+GCKI +RG+GS+R K D +G
Sbjct: 139 EKVYVPVREHPDFNFVGRILGPRGMTAKQLEQETGCKIMVRGKGSMRD-KKKEDANRGKP 197
Query: 189 N---MNEPLHCII-IADVEDKIPLGIKACESIVVK-AITSPEGQNDLKRGQLRELAVLNG 243
N +++ LH +I + D E++ + + + V K + EG+++LK+ QL ELA++NG
Sbjct: 198 NWEHLSDDLHVLITVEDTENRATVKLAQAVAEVQKLLVPQAEGEDELKKRQLMELAIING 257
Query: 244 TLRE 247
T R+
Sbjct: 258 TYRD 261
>At3g08620 [A] KOG1588 RNA-binding protein Sam68 and related KH domain
proteins
Length = 319
Score = 94.4 bits (233), Expect = 3e-19
Identities = 49/121 (40%), Positives = 80/121 (65%), Gaps = 4/121 (3%)
Query: 133 IPTEDYPDINFVGLLLGPRGNTLKKLQQESGCKISIRGRGSVRSGKAAADL--PKGAMNM 190
+P + YP+ NFVG LLGPRGN+LK+++ +GC++ IRG+GS++ + L G ++
Sbjct: 177 LPVDTYPNFNFVGRLLGPRGNSLKRVEATTGCRVYIRGKGSIKDPEKEEKLKGKPGYEHL 236
Query: 191 NEPLHCIIIADVE-DKIPLGIKACESIVVKAITS-PEGQNDLKRGQLRELAVLNGTLRED 248
NE LH +I AD+ D + + ++ + I+ + + E Q+ +KR QLRELA+LN LRE+
Sbjct: 237 NEQLHILIEADLPIDIVDIKLRQAQEIIEELVKPVDESQDYIKRQQLRELALLNSNLREN 296
Query: 249 N 249
+
Sbjct: 297 S 297
>At5g56140 [A] KOG1588 RNA-binding protein Sam68 and related KH domain
proteins
Length = 315
Score = 91.3 bits (225), Expect = 3e-18
Identities = 49/120 (40%), Positives = 78/120 (64%), Gaps = 4/120 (3%)
Query: 133 IPTEDYPDINFVGLLLGPRGNTLKKLQQESGCKISIRGRGSVRSGKAAADL--PKGAMNM 190
IP ++YP+ NFVG LLGPRGN+LK+++ + C++ IRGRGS++ + G ++
Sbjct: 172 IPVDNYPNFNFVGRLLGPRGNSLKRVEASTDCRVLIRGRGSIKDPIKEEMMRGKPGYEHL 231
Query: 191 NEPLHCIIIADVE-DKIPLGIKACESIVVKAITSPEGQNDL-KRGQLRELAVLNGTLRED 248
NEPLH ++ A++ + + + I+ +T E +D+ K+ QLRELA+LNGTLRE+
Sbjct: 232 NEPLHILVEAELPIEIVDARLMQAREILDDLLTPMEETHDMYKKQQLRELALLNGTLREE 291
>At2g38610 [A] KOG1588 RNA-binding protein Sam68 and related KH domain
proteins
Length = 286
Score = 89.0 bits (219), Expect = 1e-17
Identities = 50/122 (40%), Positives = 80/122 (64%), Gaps = 5/122 (4%)
Query: 133 IPTEDYPDINFVGLLLGPRGNTLKKLQQESGCKISIRGRGSVRSGKAAADL--PKGAMNM 190
IP ++YP+ NFVG LLGPRGN+LK+++ +GC++ IRG+GS++ + L G ++
Sbjct: 142 IPVDNYPNFNFVGRLLGPRGNSLKRVEATTGCRVFIRGKGSIKDPEKEDKLRGRPGYEHL 201
Query: 191 NEPLHCIIIADVEDKI-PLGIKACESIVVKAITS-PEGQNDLKRGQLRELAVLN-GTLRE 247
NE LH +I AD+ I + ++ + I+ + + E Q+ +KR QLRELA+LN LRE
Sbjct: 202 NEQLHILIEADLPASIVEIRLRQAQEIIEELLKPVDESQDFIKRQQLRELALLNSNNLRE 261
Query: 248 DN 249
++
Sbjct: 262 ES 263
>At4g26480_2 [A] KOG1588 RNA-binding protein Sam68 and related KH domain
proteins
Length = 285
Score = 89.0 bits (219), Expect = 1e-17
Identities = 49/121 (40%), Positives = 78/121 (63%), Gaps = 6/121 (4%)
Query: 133 IPTEDYPDINFVGLLLGPRGNTLKKLQQESGCKISIRGRGSVRSGKAAADLPKGA---MN 189
IP + YP+ NFVG LLGPRGN+LK+++ + C++ IRGRGS++ D+ +G +
Sbjct: 143 IPVDKYPNYNFVGRLLGPRGNSLKRVEASTDCRVLIRGRGSIKD-PIKEDMMRGKPGYEH 201
Query: 190 MNEPLHCIIIADVE-DKIPLGIKACESIVVKAITSPEGQNDL-KRGQLRELAVLNGTLRE 247
+NEPLH ++ A++ + + + I+ +T E +D K+ QLRELA+LNG+LRE
Sbjct: 202 LNEPLHILVEAELPIEIVDARLMQAREILDDLLTPVEETHDFYKKQQLRELALLNGSLRE 261
Query: 248 D 248
+
Sbjct: 262 E 262
>At1g09660 [A] KOG1588 RNA-binding protein Sam68 and related KH domain
proteins
Length = 163
Score = 85.1 bits (209), Expect = 2e-16
Identities = 48/121 (39%), Positives = 73/121 (59%), Gaps = 4/121 (3%)
Query: 133 IPTEDYPDINFVGLLLGPRGNTLKKLQQESGCKISIRGRGSVRSGKAAADL--PKGAMNM 190
+P + YP NFVG +LGPRGN+LK+++ + C++ IRGRGSV+ L G ++
Sbjct: 18 VPVDKYPSYNFVGRILGPRGNSLKRVELATHCRVFIRGRGSVKDTVKEEKLKGKPGYEHL 77
Query: 191 NEPLHCIIIADVEDKIPLGIKACESIVVKAITSP--EGQNDLKRGQLRELAVLNGTLRED 248
EPLH +I A++ + I ++++ P E + KR QL+ELA LNGTLRE+
Sbjct: 78 CEPLHVLIEAELPEDIINSRLEHAVHFLESLLKPMDESMDHYKREQLKELAALNGTLREE 137
Query: 249 N 249
+
Sbjct: 138 S 138
>Hs20553511 [A] KOG1588 RNA-binding protein Sam68 and related KH domain
proteins
Length = 349
Score = 81.3 bits (199), Expect = 3e-15
Identities = 53/151 (35%), Positives = 84/151 (55%), Gaps = 11/151 (7%)
Query: 126 RFQDKYYIPTEDYPDINFVGLLLGPRGNTLKKLQQESGCKISIRGRGSVRSGKAAADLPK 185
+ ++ IP + YP NFVG LLGPRGN+LK+LQ+E+G K+SI G+GS+R +L K
Sbjct: 59 KLSERVLIPVKQYPKFNFVGKLLGPRGNSLKRLQEETGAKMSILGKGSMRDKAKEEELRK 118
Query: 186 GA----MNMNEPLHCII--IADVEDKIPLGIKACESIVVKAITSPEGQNDLKRGQLRELA 239
++++ LH +I A + A E I K P+ +++++ QLREL+
Sbjct: 119 SGEAKYAHLSDELHVLIEVFAPPGEAYSRMSHALEEI--KKFLVPDYNDEIRQEQLRELS 176
Query: 240 VLNGTLREDNYVQTFGRKRIGIEVASDAAKR 270
LNG+ ++ + G + GI +A A R
Sbjct: 177 YLNGS---EDSGRGRGIRGRGIRIAPTAPSR 204
>CE27520 [A] KOG1588 RNA-binding protein Sam68 and related KH domain
proteins
Length = 576
Score = 80.5 bits (197), Expect = 5e-15
Identities = 54/182 (29%), Positives = 94/182 (50%), Gaps = 26/182 (14%)
Query: 112 IPNFVTPDDYRRPTRFQ------DKYYIPTEDYPDINFVGLLLGPRGNTLKKLQQESGCK 165
+P F+ +D R Q + +P E YP NFVG +LGPRG T+K+L++E+GC+
Sbjct: 242 LPRFMRNNDNYHDQRRQFVVTLSEILMVPVEKYPKYNFVGRILGPRGMTVKQLEKETGCR 301
Query: 166 ISIRGRGSVRSGKAAADLPKGAMNMNEPLHCIIIADVEDKIPLGI-------------KA 212
I +RGR S + + K + ++P II + + PL + K
Sbjct: 302 IFVRGRASTTASNPESKPNKSTPSFSKPSLSIISRNALTEEPLHVYIECQDTQSAAQAKM 361
Query: 213 CESI-VVKAITSP--EGQNDLKRGQLRELAVLNGTLR----EDNYVQTFGRKRIGIEVAS 265
++ V++ + SP +G+++LKR QL +++++NGT R + +V F R R + S
Sbjct: 362 AHAVEVIQRLLSPPKDGKDELKRQQLVDISLINGTYRVTSTSNEHVGQFRRPRYSADPTS 421
Query: 266 DA 267
++
Sbjct: 422 NS 423
>Hs5730027 [A] KOG1588 RNA-binding protein Sam68 and related KH domain
proteins
Length = 443
Score = 78.2 bits (191), Expect = 2e-14
Identities = 44/122 (36%), Positives = 67/122 (54%), Gaps = 4/122 (3%)
Query: 126 RFQDKYYIPTEDYPDINFVGLLLGPRGNTLKKLQQESGCKISIRGRGSVRSGKAAADLPK 185
+ +++ IP + YP NFVG +LGP+GNT+K+LQ+E+G KIS+ G+GS+R +L K
Sbjct: 155 KLKERVLIPVKQYPKFNFVGKILGPQGNTIKRLQEETGAKISVLGKGSMRDKAKEEELRK 214
Query: 186 GA----MNMNEPLHCIIIADVEDKIPLGIKACESIVVKAITSPEGQNDLKRGQLRELAVL 241
G ++N LH I + A VK P+ +D+ + Q EL+ L
Sbjct: 215 GGDPKYAHLNMDLHVFIEVFGPPCEAYALMAHAMEEVKKFLVPDMMDDICQEQFLELSYL 274
Query: 242 NG 243
NG
Sbjct: 275 NG 276
>CE18029 [A] KOG1588 RNA-binding protein Sam68 and related KH domain
proteins
Length = 254
Score = 77.0 bits (188), Expect = 5e-14
Identities = 45/121 (37%), Positives = 70/121 (57%), Gaps = 9/121 (7%)
Query: 133 IPTEDYPDINFVGLLLGPRGNTLKKLQQESGCKISIRGRGSVRS-----GKAAADLPKGA 187
IP E YP NF+G ++GPRG T K+L++++GC+I IRG S + K D + A
Sbjct: 127 IPVETYPTYNFIGRIIGPRGTTAKQLEKDTGCRIMIRGNHSNKMYGNALHKTHGDGSQDA 186
Query: 188 MNMNEPLHCIIIADVEDKIPLG--IKACESIVVKAITSPEGQNDLKRGQLRELAVLNGTL 245
+++ PL I+ + A E++ V + P+G+++LKR QL ELA++NGT
Sbjct: 187 IDL--PLRVIVETSGPRREATARITAALETVQVLLVPPPDGRDELKRRQLVELAIMNGTY 244
Query: 246 R 246
R
Sbjct: 245 R 245
>Hs5730073 [A] KOG1588 RNA-binding protein Sam68 and related KH domain
proteins
Length = 346
Score = 74.3 bits (181), Expect = 3e-13
Identities = 46/120 (38%), Positives = 68/120 (56%), Gaps = 8/120 (6%)
Query: 130 KYYIPTEDYPDINFVGLLLGPRGNTLKKLQQESGCKISIRGRGSVRSGKAAADLPKGA-- 187
K IP + +P NFVG LLGPRGN+LK+LQ+E+ K+SI G+GS+R +L K
Sbjct: 59 KVLIPVKQFPKFNFVGKLLGPRGNSLKRLQEETLTKMSILGKGSMRDKAKEEELRKSGEA 118
Query: 188 --MNMNEPLHCII--IADVEDKIPLGIKACESIVVKAITSPEGQNDLKRGQLRELAVLNG 243
++N+ LH +I A + A E I K P+ +++++ QL+EL LNG
Sbjct: 119 KYFHLNDDLHVLIEVFAPPAEAYARMGHALEEI--KKFLIPDYNDEIRQAQLQELTYLNG 176
>7302782 [A] KOG1588 RNA-binding protein Sam68 and related KH domain
proteins
Length = 428
Score = 68.9 bits (167), Expect = 1e-11
Identities = 47/146 (32%), Positives = 75/146 (51%), Gaps = 9/146 (6%)
Query: 119 DDYR-RPTRFQDKYYIPTEDYPDINFVGLLLGPRGNTLKKLQQESGCKISIRGRGSVRSG 177
D YR +P R + +P ++P NFVG LLGP+GN+L++LQ+E+ CK+++ GR S+R
Sbjct: 112 DIYREKPLRISQRVLVPIREHPKFNFVGKLLGPKGNSLRRLQEETLCKMTVLGRNSMRDR 171
Query: 178 KAAADL-----PKGAMNMNEPLHCIIIADVEDKIPLGIKACESIVVKAITSPEGQNDLKR 232
+L PK A ++N LH I A ++ P+ + +++
Sbjct: 172 VKEEELRSSKDPKYA-HLNSDLHVEISTIAPPAEAYARIAYAMAELRKYLIPDSNDIIRQ 230
Query: 233 GQLRELAVLNGTLREDNYVQTFGRKR 258
QLREL ++ T DN G K+
Sbjct: 231 EQLREL--MDSTSLNDNDNAKSGYKK 254
>7291417 [A] KOG1588 RNA-binding protein Sam68 and related KH domain
proteins
Length = 396
Score = 68.9 bits (167), Expect = 1e-11
Identities = 46/155 (29%), Positives = 77/155 (49%), Gaps = 16/155 (10%)
Query: 94 KRKLEEERHRLVEIALKMIPNFVTPDDYRRPTRFQDKYYIPTEDYPDINFVGLLLGPRGN 153
KR L++E +++ P +P R K P ++YP NFVG +LGP+GN
Sbjct: 80 KRLLDDEVEKILVSGRIPKPEIYANVYSEKPIRVAQKVLFPIKEYPKFNFVGKILGPKGN 139
Query: 154 TLKKLQQESGCKISIRGRGSVRSGKAAADL-----PKGAMNMNEPLHCIII-----ADVE 203
TL++LQ+E+ CK+ + GR S+R +L PK A +++ LH I A+
Sbjct: 140 TLRQLQEETMCKMVVMGRNSMRDHGKEEELRSSGNPKYA-HLSRDLHVEISTVAPPAEAY 198
Query: 204 DKIPLGIKACESIVVKAITSPEGQNDLKRGQLREL 238
+I + ++ P+ +D++ QLRE+
Sbjct: 199 HRISYALGEIRKFMI-----PDANDDIRLEQLREM 228
>7291415 [A] KOG1588 RNA-binding protein Sam68 and related KH domain
proteins
Length = 317
Score = 68.9 bits (167), Expect = 1e-11
Identities = 36/109 (33%), Positives = 59/109 (54%), Gaps = 18/109 (16%)
Query: 85 RTNTKEQRYKRKLEEERHRL----------VEIALKMI--------PNFVTPDDYRRPTR 126
R N Q++ L+EER RL ++ A+ + F ++P +
Sbjct: 20 RLNEVAQKFLADLDEERQRLSADFPLCALLIDEAVDRVYCTGRIPGKEFYADVYKQKPMK 79
Query: 127 FQDKYYIPTEDYPDINFVGLLLGPRGNTLKKLQQESGCKISIRGRGSVR 175
K ++P + YP NF G +LGP+GN+L++LQ+E+ CKI+I+GR S+R
Sbjct: 80 ITQKVFVPVKQYPKFNFTGKILGPKGNSLRRLQEETQCKIAIKGRSSIR 128
>7291333 [A] KOG1588 RNA-binding protein Sam68 and related KH domain
proteins
Length = 316
Score = 68.6 bits (166), Expect = 2e-11
Identities = 53/179 (29%), Positives = 84/179 (46%), Gaps = 30/179 (16%)
Query: 85 RTNTKEQRYKRKLEEERHRLVE----------------IALKMIPNF-VTPDDYR-RPTR 126
R N Q++ L+EER RL A IP + D YR +P +
Sbjct: 21 RLNEIAQKFLADLDEERQRLSAEFPLCALLIDEARDRVYATGRIPGKELYADVYRQKPMK 80
Query: 127 FQDKYYIPTEDYPDINFVGLLLGPRGNTLKKLQQESGCKISIRGRGSVRSGKAAADL--- 183
K ++P YP NF G +LGP+GN+L++LQ+E+ CKI+++GR S+R +L
Sbjct: 81 IIQKVFVPVNQYPKFNFAGKILGPKGNSLRRLQEETQCKIALKGRSSMRDRNKEEELRSD 140
Query: 184 PKGA-MNMN---EPLHCIIIADVEDKIPLGIKACESIVVKAITSPEGQNDLKRGQLREL 238
P+ A + N E I A+ +I + ++ P+ +++ QLREL
Sbjct: 141 PRYAHLQKNLFLEVSTVAIPAECHSRIAYALAEIRKYLI-----PDNNDEVSHEQLREL 194
>7291423 [A] KOG1588 RNA-binding protein Sam68 and related KH domain
proteins
Length = 470
Score = 68.2 bits (165), Expect = 2e-11
Identities = 41/130 (31%), Positives = 71/130 (54%), Gaps = 12/130 (9%)
Query: 123 RPTRFQDKYYIPTEDYPDINFVGLLLGPRGNTLKKLQQESGCKISIRGRGSVRSGKAAAD 182
+P + K +P D+P NFVG LLGP+GN++K+LQ+++ CK+++ GRGS+R + +
Sbjct: 8 KPVKVAVKVAVPVRDHPKFNFVGKLLGPKGNSMKRLQEDTMCKMAVLGRGSMRDRRKEEE 67
Query: 183 LPKGA-----MNMNEPLHCII---IADVEDKIPLGIKACESIVVKAITSPEGQNDLKRGQ 234
L +G+ ++ E LH I A E + E V+ P+ +D+++ Q
Sbjct: 68 L-RGSGDSRYAHLFEDLHVEISTFAAPAEAHARIAYALAE---VRRFLVPDYHDDIRQEQ 123
Query: 235 LRELAVLNGT 244
+ E+ L T
Sbjct: 124 MWEMQALTST 133
>7291433 [A] KOG1588 RNA-binding protein Sam68 and related KH domain
proteins
Length = 266
Score = 67.4 bits (163), Expect = 4e-11
Identities = 38/127 (29%), Positives = 63/127 (48%), Gaps = 8/127 (6%)
Query: 122 RRPTRFQDKYYIPTEDYPDINFVGLLLGPRGNTLKKLQQESGCKISIRGRGSVRSGKAAA 181
++P + K ++P +P NF G +LGP+GN+L++LQ+E+ CKI I+GR S+R
Sbjct: 76 QKPMKIIQKVFVPVNKFPKFNFTGKILGPKGNSLRRLQEETHCKIVIKGRNSMRDRNKEE 135
Query: 182 DLPKGAMNMNEPLHCIIIADVEDKIPLGIKACESIVVKAITS------PEGQNDLKRGQL 235
+L LH + +V P C + + A+ P+ +D+ Q
Sbjct: 136 ELRSSGDPRYAHLHKDLFLEVSAVAPPA--ECYARIAYALAEIRKYLIPDDNDDVWHEQQ 193
Query: 236 RELAVLN 242
REL +N
Sbjct: 194 RELMEMN 200
>7291418 [A] KOG1588 RNA-binding protein Sam68 and related KH domain
proteins
Length = 416
Score = 66.2 bits (160), Expect = 9e-11
Identities = 49/170 (28%), Positives = 83/170 (48%), Gaps = 23/170 (13%)
Query: 91 QRYKRKLEEERHRLVE---IALKMIPNFV----------TPDDY-----RRPTRFQDKYY 132
Q+Y ++L ER R+ +A+K+I + T D Y +R + K +
Sbjct: 74 QKYMQELMTERSRMENHFPLAVKLIDEALERVQLNGRIPTRDQYADVYQQRTIKLSQKVH 133
Query: 133 IPTEDYPDINFVGLLLGPRGNTLKKLQQESGCKISIRGRGSVRSGKAAADLPKGA----M 188
+P +D N+VG LLGP+GN+L++LQ+E+ CKI I GR S++ +L A
Sbjct: 134 VPIKD-KKFNYVGKLLGPKGNSLRRLQEETQCKIVILGRFSMKDRAREEELRNSADAKYA 192
Query: 189 NMNEPLHCIIIADVEDKIPLGIKACESIVVKAITSPEGQNDLKRGQLREL 238
++N PLH + A ++ +P+ +D+++ Q REL
Sbjct: 193 HLNLPLHVEVSTIAPPAEAYARVAYALAEIRRYLTPDKHDDIRQEQYREL 242
>CE29534_2 [A] KOG1588 RNA-binding protein Sam68 and related KH domain
proteins
Length = 105
Score = 61.2 bits (147), Expect = 3e-09
Identities = 35/107 (32%), Positives = 65/107 (60%), Gaps = 6/107 (5%)
Query: 144 VGLLLGPRGNTLKKLQQESGCKISIRGRGSVRSGKAAADLPK--GAMNMNEPLHCIII-- 199
VG L+GPRG T+++L+++ GCK+ IRG+G + L + G ++ EP+H +I
Sbjct: 1 VGRLIGPRGMTIRQLEKDLGCKLFIRGKGCTKDDAKEERLRERVGWEHLKEPIHVMISVR 60
Query: 200 ADVEDKIPLGIKACESIVVKAITSPEGQNDLKRGQLRELAVLNGTLR 246
+D E+ + + + ++ + + + ++LKR QL +LAV+ GTL+
Sbjct: 61 SDSEEAASEKLSSIKKMLQEFLEHTD--SELKRSQLMQLAVIEGTLK 105
>ECU02g1160 [A] KOG0119 Splicing factor 1/branch point binding protein (RRM
superfamily)
Length = 203
Score = 59.3 bits (142), Expect = 1e-08
Identities = 33/112 (29%), Positives = 60/112 (53%), Gaps = 16/112 (14%)
Query: 127 FQDKYYIPTEDYPDINFVGLLLGPRGNTLKKLQQESGCKISIRGRGSVRSGKAAADLPKG 186
+ +K YIP +++P+ NFVGL++GPRG+T K+L++ + +I IRG +
Sbjct: 76 YTNKIYIPVQEFPESNFVGLIIGPRGSTQKQLERITRARIYIRGSYKDKH---------- 125
Query: 187 AMNMNEPLHCIIIADVEDKIPLGIKACESIVVKAITSPEGQNDLKRGQLREL 238
EPLHC I A+ ++ + E+++ ++ G L+ QL+ +
Sbjct: 126 ----VEPLHCYISAETQESLKNASAVIENLIEDSVLF--GDCRLRMSQLQAI 171
>CE05936 [A] KOG1588 RNA-binding protein Sam68 and related KH domain
proteins
Length = 278
Score = 57.0 bits (136), Expect = 6e-08
Identities = 41/131 (31%), Positives = 61/131 (46%), Gaps = 16/131 (12%)
Query: 128 QDKYYIPTEDYP------DINFVGLLLGPRGNTLKKLQQESGCKISIRGRGSVRSGKAAA 181
Q K YIP N++G +LGP G + + ++ + + IRG GSVR+
Sbjct: 133 QTKVYIPEPPVSIDGKKVKCNYIGRILGPSGMSARMIENQYDVTLLIRGAGSVRNKAMDE 192
Query: 182 DLPKGAMNMNEPLHCIIIADVEDKIPLGIKACESIVVKAITSPEG-----QNDLKRGQLR 236
+ K ++ EPLH ++IA DK CE I+ KA E ++ K QL
Sbjct: 193 RVRKRNEHLEEPLHVLLIARHNDK-----TKCEEILNKAAEKIESLLTPIHDEYKMDQLV 247
Query: 237 ELAVLNGTLRE 247
A +NGT +E
Sbjct: 248 SYAKMNGTYQE 258
>CE08610 [A] KOG1588 RNA-binding protein Sam68 and related KH domain
proteins
Length = 315
Score = 53.1 bits (126), Expect = 8e-07
Identities = 33/102 (32%), Positives = 54/102 (52%), Gaps = 10/102 (9%)
Query: 103 RLVEIALKMIPNFVTPD----DYRRPTRFQDKYYIPTEDYPDINFVGLLLGPRGNTLKKL 158
RL+ + + N + P+ D +P + K +P +P+ NF+G +LGP+G TL+ L
Sbjct: 101 RLLNSEKERLENNIDPEWLEVDVAKPVKVCKKILVPIYRHPNFNFIGKVLGPKGATLQTL 160
Query: 159 QQESGCKISIRGRGSVRSGKAAADL-----PKGAMNMNEPLH 195
+ C I I GRGS + + A+L P+ A + + PLH
Sbjct: 161 CKTHKCHIYILGRGSTKDREKEAELLASGDPQHA-HFSGPLH 201
>At3g32940 [A] KOG0119 Splicing factor 1/branch point binding protein (RRM
superfamily)
Length = 590
Score = 50.1 bits (118), Expect = 7e-06
Identities = 44/214 (20%), Positives = 97/214 (44%), Gaps = 23/214 (10%)
Query: 95 RKLEEERHRLVEIALKMIPNFVTPDDYRRPTRFQDKYYIPTEDYPDINFVGLLLGPRGNT 154
++LE E+ + L++ P + P DY+ P + + I +++ D +F+ L+ G +G+T
Sbjct: 85 QQLEFEKREAIGEILELNPRYKAPPDYK-PLLKEARLPIDVKEHSDFSFLSLIFGSQGDT 143
Query: 155 LKKLQQESGCKISIRGRGSVRSGKAAADLPKGAMN----MNEPLHCIIIADVEDKIPLGI 210
K+L++E+G K+ I G ++G +L N + L+ I +D +K+ I
Sbjct: 144 QKRLEKETGAKVQIFG---TKTGGEKVELSPSDENEIQKSWQELYFQISSDTYEKVDAAI 200
Query: 211 KACESIVVKAITSPEGQNDLKRGQLRELAVLNGTLREDNYVQTFGRKRIGIEVASDAAKR 270
E +++ +++ G + E+ + T I A + +
Sbjct: 201 AVVE-LLMSSVSGNTGAGAAPPSSISEI------------ISTIPGNSIATATAPTSERT 247
Query: 271 FKNAESNIHDQSTIVNTHR--LTPMMQISIDGLG 302
+++ H S +++++ L P ++ + GLG
Sbjct: 248 TDHSQVLQHGSSFHLSSNQAPLHPPLEHFVSGLG 281
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.316 0.135 0.387
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,072,717
Number of Sequences: 60738
Number of extensions: 815439
Number of successful extensions: 2098
Number of sequences better than 1.0e-05: 32
Number of HSP's better than 0.0 without gapping: 28
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 2041
Number of HSP's gapped (non-prelim): 32
length of query: 459
length of database: 30,389,216
effective HSP length: 110
effective length of query: 349
effective length of database: 23,708,036
effective search space: 8274104564
effective search space used: 8274104564
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)