ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI4928 good L KOG2928 Replication, recombination and repair Origin recognition complex, subunit 2
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI4928 1709034 1710821 596
(596 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YBR060c [L] KOG2928 Origin recognition complex subunit 2 340 5e-93
SPBC685.09 [L] KOG2928 Origin recognition complex subunit 2 147 4e-35
7299828 [L] KOG2928 Origin recognition complex subunit 2 136 1e-31
Hs5453830 [L] KOG2928 Origin recognition complex subunit 2 132 1e-30
At2g37560 [L] KOG2928 Origin recognition complex subunit 2 122 2e-27
CE11492 [L] KOG2928 Origin recognition complex subunit 2 77 1e-13
>YBR060c [L] KOG2928 Origin recognition complex subunit 2
Length = 620
Score = 340 bits (871), Expect = 5e-93
Identities = 206/563 (36%), Positives = 321/563 (56%), Gaps = 37/563 (6%)
Query: 46 SPSKTVRPKSPKRSLTLESVSIETEYKDEESRKHSSTDTAXXXXXXXXXXXXXXLEEDDA 105
+P K RP+ + LT E + + ++ DT+ + E
Sbjct: 74 APRKRGRPRKIQEELTDRIKKDEKDTISSKKKRKLDKDTSGNVNEESKTSNNKQVMEKTG 133
Query: 106 IDYVSDTNELIHNDDEYED-LKIKIDSNESSPNKSPRRKLTFNAEPSPQRKTTRN--TVQ 162
I + ++ YED + + D N S + P T PS + TT + T
Sbjct: 134 IKEKREREKIQVATTTYEDNVTPQTDDNFVSNSPEPPEPAT----PSKKSLTTNHDFTSP 189
Query: 163 RNKIIDDDLAYDDIQQYKHL----KLNLNPNFKPTKLPKSDNNDQTSDEQSQIYFFDGFE 218
+II ++L ++YK KL L+ NF PT +PK+ QTS+ +S F D FE
Sbjct: 190 LKQIIMNNL-----KEYKDSTSPGKLTLSRNFTPTPVPKNKKLYQTSETKSASSFLDTFE 244
Query: 219 GFIDQTKILKTDKRSKNSMSSAPSISRDEYNILSQLSNDIFHRSSTKAVQKIHETLFQQF 278
G+ DQ KI++T+ +S+++MS AP ++R+E++++S N+ F + + + +I + +F Q+
Sbjct: 245 GYFDQRKIVRTNAKSRHTMSMAPDVTREEFSLVSNFFNENFQKRPRQKLFEIQKKMFPQY 304
Query: 279 TFELLQGFTLLFYGIGSKKKFLESFAFNFLSMKIA---LLQNPDIQKDDP--CIPVFVMN 333
FEL QGF+LLFYG+GSK+ FLE FA ++LS KIA L ++Q++ P IP ++N
Sbjct: 305 WFELTQGFSLLFYGVGSKRNFLEEFAIDYLSPKIAYSQLAYENELQQNKPVNSIPCLILN 364
Query: 334 GYTTLS--KNIFLDIFKILVEGETIDDQGQSNYWDNRIDLQMDRLSKYFKKRPPTVKMIL 391
GY +++F +I +LV E + ++ YW N + LQ+ ++ ++K +P +K+IL
Sbjct: 365 GYNPSCNYRDVFKEITDLLVPAEL--TRSETKYWGNHVILQIQKMIDFYKNQPLDIKLIL 422
Query: 392 LIHNLDGPSFRREHFQTRMSILAQIKQICVVASVDHIQAPFLWDHFRAQSFNFVYHDITN 451
++HNLDGPS R+ FQT +S L+ I+QI +VAS DHI AP LWD+ +AQ++NFV+HDI+N
Sbjct: 423 VVHNLDGPSIRKNTFQTMLSFLSVIRQIAIVASTDHIYAPLLWDNMKAQNYNFVFHDISN 482
Query: 452 FEPYIVETVQTDNAIDFSKDSGTLFNANGAKYVLESLTDNSKRMYKILLQLL---MGQIN 508
FEP VE+ D + K S T A GAKYVL+SLT NSK+MYK+L++ MG ++
Sbjct: 483 FEPSTVESTFQD-VMKMGK-SDTSSGAEGAKYVLQSLTVNSKKMYKLLIETQMQNMGNLS 540
Query: 509 AKNESKPRAKSSSLNKITPGIEFSELFKTCTEQFVVSSEMGLRTILSEFIDHKMAVNTKN 568
A K + + G+E C F+ S+E+ LR++L EFI+HKMA TKN
Sbjct: 541 ANTGPKRGTQRT-------GVELKLFNHLCAADFIASNEIALRSMLREFIEHKMANITKN 593
Query: 569 KMGKEIINVKYSYGDMEKMITEI 591
G EII V Y+Y ++EK++ +
Sbjct: 594 NSGMEIIWVPYTYAELEKLLKTV 616
>SPBC685.09 [L] KOG2928 Origin recognition complex subunit 2
Length = 535
Score = 147 bits (371), Expect = 4e-35
Identities = 108/382 (28%), Positives = 175/382 (45%), Gaps = 48/382 (12%)
Query: 216 GFEGFIDQTKILKTDKRSKNSMSSAPSISRDEY-NILSQLSNDIFHRSSTKAVQKIHETL 274
GF+ + D+ KT S N++S P + Y + + ++ + T+ +
Sbjct: 192 GFDEYFDKFSQRKT---SSNTLSQLPVLDNQVYLDTVKEICTET--EQHTQTLVHFQSRN 246
Query: 275 FQQFTFELLQGFTLLFYGIGSKKKFLESFAFNFLSMKIALLQNPDIQKDDPCIPVFVMNG 334
F Q+ FEL+ F LLFYG GSK+ FL SF ++K PC P+FV+ G
Sbjct: 247 FHQWYFELVNNFNLLFYGFGSKEHFLSSF----------------VEKKLPCFPIFVVKG 290
Query: 335 Y--TTLSKNI---FLDIFKILVEGETIDDQGQSNYWDNRIDLQMDRLSKYFKKRPPTVKM 389
Y KN+ FL+ ++ D QS N + K+
Sbjct: 291 YFPQLQLKNVLSSFLEFLEVTPAASVSDMLIQSLSIINSPSFSLG-------------KI 337
Query: 390 ILLIHNLDGPSFRREHFQTRMSILAQIKQICVVASVDHIQAPFLWDHFRAQSFNFVYHDI 449
+ L+HN+DG S E FQ+ ++ +A K + +ASVDH+ LWD SFNFV HD
Sbjct: 338 VFLVHNIDGESLIDERFQSALAAIASSKNVYFIASVDHVNFALLWDTSLESSFNFVMHDA 397
Query: 450 TNFEPYIVETVQTDNAIDFSKDSGTLFNANGAKYVLESLTDNSKRMYKILLQLLMGQINA 509
T F Y ET +N++ + + K+VL SL NS+ ++K LL + ++
Sbjct: 398 TTFARYYNETTY-ENSLGIGR-ANVSNKEKAIKHVLYSLPANSRGIFKFLLIHQLERMMD 455
Query: 510 KNESKPRAKSSSLNKITPGIEFSELFKTCTEQFVVSSEMGLRTILSEFIDHKMAVNTKNK 569
+ R GIE+ F+ C+ +F+ S+E R+ L+EF DH + + ++
Sbjct: 456 TQDFDARQGEK------VGIEYRSFFQKCSAEFLCSNEPNFRSQLTEFFDHNIIESKRDV 509
Query: 570 MGKEIINVKYSYGDMEKMITEI 591
EI+ V Y +E ++ ++
Sbjct: 510 SNSEILWVPYPKNLLEILLEDM 531
>7299828 [L] KOG2928 Origin recognition complex subunit 2
Length = 618
Score = 136 bits (342), Expect = 1e-31
Identities = 109/380 (28%), Positives = 183/380 (47%), Gaps = 50/380 (13%)
Query: 215 DGFEGFIDQTKILKTDK---RSKNSMSSAPSISRDEYNILSQLSNDIFHRSSTKAVQKIH 271
DG+ +KIL +D R KN +A + +++LS++ H S A+ + +
Sbjct: 281 DGYFHSHASSKILTSDHTLDRLKNPRLAADRV----FSLLSEIKTSAEHEGSINAIMEEY 336
Query: 272 ETLFQQFTFELLQGFTLLFYGIGSKKKFLESFAFNFLSMKIALLQNPDIQKDDPCIPVFV 331
+ F ++ L +GF +L YG+GSK + L+SF L + L V
Sbjct: 337 RSYFPKWMCILNEGFNILLYGLGSKHQLLQSFHREVLHKQTVL----------------V 380
Query: 332 MNGY-TTLSKNIFLDIFKILVEGETIDDQGQSNYWDNRIDLQMDRLSKYFKKRPPTVKMI 390
+NG+ +L+ LD I D G S + +D + + F P T +
Sbjct: 381 VNGFFPSLTIKDMLDSIT-----SDILDAGISPANPHEA---VDMIEEEFALIPET-HLF 431
Query: 391 LLIHNLDGPSFRREHFQTRMSILAQIKQICVVASVDHIQAPFLWDHFRAQSFNFVYHDIT 450
L++HNLDG R Q +S LA+I I ++AS+DHI P LWD + SFNF + D T
Sbjct: 432 LIVHNLDGAMLRNVKAQAILSRLARIPNIHLLASIDHINTPLLWDQGKLCSFNFSWWDCT 491
Query: 451 NFEPYIVETVQTDNAIDFSKDSGTLFNANGAKYVLESLTDNSKRMYKILLQLLMGQINAK 510
PY ET ++ + ++SG L + + V SLT NS+ +Y ++++ + K
Sbjct: 492 TMLPYTNETAFENSLL--VQNSGEL-ALSSMRSVFSSLTTNSRGIYMLIVKYQL-----K 543
Query: 511 NESKPRAKSSSLNKITPGIEFSELFKTCTEQFVVSSEMGLRTILSEFIDHKMAVNTKNKM 570
N+ N G+ F +L+ +C E F+VSS++ LR L+EF+DHK+ + ++
Sbjct: 544 NKG---------NATYQGMPFRDLYSSCREAFLVSSDLALRAQLTEFLDHKLVKSKRSVD 594
Query: 571 GKEIINVKYSYGDMEKMITE 590
G E + + +++ + E
Sbjct: 595 GSEQLTIPIDGALLQQFLEE 614
>Hs5453830 [L] KOG2928 Origin recognition complex subunit 2
Length = 577
Score = 132 bits (333), Expect = 1e-30
Identities = 103/394 (26%), Positives = 185/394 (46%), Gaps = 55/394 (13%)
Query: 192 PTKLPKSDNNDQTSDEQSQIYFFDGFEGFIDQTKILKTDKRSKNSMSSAPSISRDEYNIL 251
P+K K D +E + + +K+L +D R+ + A + N+L
Sbjct: 227 PSKRMKRDKTSDLVEEYFEAH---------SSSKVLTSD-RTLQKLKRAKLDQQTLRNLL 276
Query: 252 SQLSNDIFHRSSTKAVQKIHETLFQQFTFELLQGFTLLFYGIGSKKKFLESFAFNFLSMK 311
S++S + K + + +E LF ++ +L GF ++ YG+GSK+ LE F L
Sbjct: 277 SKVSPSF--SAELKQLNQQYEKLFHKWMLQLHLGFNIVLYGLGSKRDLLERFRTTMLQDS 334
Query: 312 IALLQNPDIQKDDPCIPV-FVMNGYTTLSKNIFLDIFKILVEGETIDDQGQSNYWDNRID 370
I ++ N P I V V+N T E +D G +++D
Sbjct: 335 IHVVINGFF----PGISVKSVLNSITE----------------EVLDHMGTFRSILDQLD 374
Query: 371 LQMDRLSKYFKKRPPTVKMILLIHNLDGPSFRREHFQTRMSILAQIKQICVVASVDHIQA 430
+++ K ++++ LLIHNLD R E Q + L+ + I ++AS+DH+ A
Sbjct: 375 WIVNKF-----KEDSSLELFLLIHNLDSQMLRGEKSQQIIGQLSSLHNIYLIASIDHLNA 429
Query: 431 PFLWDHFRAQSFNFVYHDITNFEPYIVETVQTDNAIDFSKDSGTLFNANGAKYVLESLTD 490
P +WDH + FN+++++ T + PY ET ++ + K SG+L + +VL SLT
Sbjct: 430 PLMWDHAKQSLFNWLWYETTTYSPYTEETSYENSLL--VKQSGSL-PLSSLTHVLRSLTP 486
Query: 491 NSKRMYKILLQLLMGQINAKNESKPRAKSSSLNKITPGIEFSELFKTCTEQFVVSSEMGL 550
N++ ++++L++ + N+ P G+ F + ++ C E F+V+S++ L
Sbjct: 487 NARGIFRLLIKYQL-----DNQDNPS---------YIGLSFQDFYQQCREAFLVNSDLTL 532
Query: 551 RTILSEFIDHKMAVNTKNKMGKEIINVKYSYGDM 584
R L+EF DHK+ K G E + + G +
Sbjct: 533 RAQLTEFRDHKLIRTKKGTDGVEYLLIPVDNGTL 566
>At2g37560 [L] KOG2928 Origin recognition complex subunit 2
Length = 363
Score = 122 bits (306), Expect = 2e-27
Identities = 100/376 (26%), Positives = 174/376 (45%), Gaps = 56/376 (14%)
Query: 231 KRSKNSMSSAPSISRDEYNILSQLSNDIFHRSSTKAVQKIHETLFQQFTFELLQGFTLLF 290
KRS + +S + E + + ++ H + ++T++ ++ FEL GF LL
Sbjct: 29 KRSAHKLSDIHIVDEQELRETAS-TIEMKHSKEISELMSDYKTMYSKWVFELRCGFGLLM 87
Query: 291 YGIGSKKKFLESFAFNFLSMKIALLQNPDIQKDDPCIPVFVMNGY--TTLSKNIFLDIFK 348
YG GSKK +E FA L+ V V+NGY + K + L + +
Sbjct: 88 YGFGSKKALVEDFASASLTD----------------YSVVVINGYLPSVNLKQVLLALAE 131
Query: 349 ILVE-------GETIDDQGQSNYWDNRIDLQMDRLSKYFKKRPPTVK----MILLIHNLD 397
+L E +GQ + +D D LS F P + + +++HN+D
Sbjct: 132 LLSELLKCKRKSSGSLSKGQETFPSRSMD---DILS--FLHGPQSGDKDCFICVVVHNID 186
Query: 398 GPSFRREHFQTRMSILAQIKQICVVASVDHIQAPFLWDHFRA-QSFNFVYHDITNFEPYI 456
GP+ R Q ++ L+ I +VAS+DH+ AP LWD + FN+++H + F PY
Sbjct: 187 GPALRDPESQQTLARLSSCSHIRLVASIDHVNAPLLWDKKMVHKQFNWLWHHVPTFAPYN 246
Query: 457 VETVQTDNAIDFSKDSGTLFNANGAKYVLESLTDNSKRMYKILLQLLMGQINAKNESKPR 516
VE V + T A A VL+SLT N + ++KIL + Q++ +E
Sbjct: 247 VEGVFFPLVL---AQGSTAQTAKTAAIVLQSLTPNGQNVFKILAEY---QLSHPDED--- 297
Query: 517 AKSSSLNKITPGIEFSELFKTCTEQFVVSSEMGLRTILSEFIDHKMAVNTKNKMGKEIIN 576
G+ +L+ E+F VSS++ L + L+EF DH++ +N G+E +N
Sbjct: 298 -----------GMPTDDLYSASRERFFVSSQVTLNSHLTEFKDHELVKTKRNSDGQECLN 346
Query: 577 VKYSYGDMEKMITEID 592
+ + + +++ +++
Sbjct: 347 IPLTSDAIRQLLLDLN 362
>CE11492 [L] KOG2928 Origin recognition complex subunit 2
Length = 430
Score = 76.6 bits (187), Expect = 1e-13
Identities = 78/332 (23%), Positives = 149/332 (44%), Gaps = 59/332 (17%)
Query: 251 LSQLSNDIFHRSST---KAVQKIHETLFQQFTFELLQGFTLLFYGIGSKKKFLESFAFNF 307
L L N I + +T K ++ + + F ++ L GF +L +G+GSK+ L F N
Sbjct: 121 LPGLRNYITKKDNTEFEKRLEHLADNDFGKWKLYLAAGFNILLHGVGSKRDVLTEFE-NE 179
Query: 308 LSMKIALLQNPDIQKDDPCIPVFV--MNGYTTLSKNIFLDIFKILVEGETIDDQGQSNY- 364
LS + D +KD + V + +N L+ N+ +GQS
Sbjct: 180 LSDYTYM--RVDARKDGLNVKVLLGAINENMKLNCNV---------------KRGQSTIS 222
Query: 365 WDNRIDLQMDRLSKYFKKRPPTVKMILLIHNLDGPSFRREHFQTRMSILAQIKQICVVAS 424
W I +M+ + ++IL+I N++ P +R + + +L + ++A+
Sbjct: 223 WARSIRRKMN-----------SQQLILIIDNIEAPDWRSDQ-EAFCELLENRDSVKLIAT 270
Query: 425 VDHIQAPFLWDHFRAQSFNFVYHDITNFEPYIVETVQTDN---AIDFSKDSGTLFNANGA 481
VDHI + F+W+ + S +FV+ I FE + E + D+ +D ++ + + +
Sbjct: 271 VDHIYSTFIWNSRQLSSLSFVHITINTFEIPLQELMTGDSRLLGLD-ARSNQSSHTMSSL 329
Query: 482 KYVLESLTDNSKRMYKILLQLLMGQINAKNESKPRAKSSSLNKITPGIEFSELFKTCTEQ 541
+SL NS++++++ Q+ + KP ++F +LF +
Sbjct: 330 DVFWKSLAVNSQKLFRLFFQMYF------DTKKP-------------VKFWDLFNAAKDD 370
Query: 542 FVVSSEMGLRTILSEFIDHKMAVNTKNKMGKE 573
F+ S++ LRT L EF DH++ T+ G +
Sbjct: 371 FIASTDAALRTQLVEFKDHRVLKWTRGDDGND 402
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.316 0.133 0.371
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,875,018
Number of Sequences: 60738
Number of extensions: 1450990
Number of successful extensions: 4821
Number of sequences better than 1.0e-05: 6
Number of HSP's better than 0.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 4797
Number of HSP's gapped (non-prelim): 10
length of query: 596
length of database: 30,389,216
effective HSP length: 112
effective length of query: 484
effective length of database: 23,586,560
effective search space: 11415895040
effective search space used: 11415895040
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)