ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI4935 check: MH T KOG1989 Signal transduction mechanisms ARK protein kinase family
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI4935 1711131 1713572 814
(814 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YBR059c [T] KOG1989 ARK protein kinase family 536 e-152
YIL095w [T] KOG1989 ARK protein kinase family 278 3e-74
YNL020c [T] KOG1989 ARK protein kinase family 265 2e-70
SPBC557.04 [T] KOG1989 ARK protein kinase family 250 5e-66
SPBC6B1.02 [T] KOG1989 ARK protein kinase family 243 9e-64
SPCP1E11.02 [T] KOG1989 ARK protein kinase family 213 7e-55
Hs9055206 [T] KOG1989 ARK protein kinase family 196 1e-49
Hs7662462 [T] KOG1989 ARK protein kinase family 186 1e-46
7298508 [T] KOG1989 ARK protein kinase family 176 1e-43
At2g32850 [T] KOG1989 ARK protein kinase family 166 1e-40
Hs4885251_1 [T] KOG1989 ARK protein kinase family 162 2e-39
7296894_1 [T] KOG1989 ARK protein kinase family 148 4e-35
CE00972 [T] KOG1989 ARK protein kinase family 139 2e-32
CE00971 [T] KOG1989 ARK protein kinase family 139 2e-32
CE04586 [T] KOG1989 ARK protein kinase family 109 2e-23
At5g08160 [KIT] KOG2345 Serine/threonine protein kinase/TGF-beta... 101 5e-21
SPAC19E9.02 [D] KOG0591 NIMA (never in mitosis)-related G2-speci... 93 1e-18
YPL236c [KIT] KOG2345 Serine/threonine protein kinase/TGF-beta s... 92 4e-18
SPAC23C11.16 [D] KOG0575 Polo-like serine/threonine protein kinase 90 2e-17
CE26793_1 [R] KOG0611 Predicted serine/threonine protein kinase 89 4e-17
Hs7662170 [R] KOG0611 Predicted serine/threonine protein kinase 87 1e-16
At1g66880 [T] KOG1187 Serine/threonine protein kinase 86 2e-16
SPAC890.03 [T] KOG0583 Serine/threonine protein kinase 86 3e-16
YPL150w [T] KOG0583 Serine/threonine protein kinase 85 4e-16
At4g23050 [T] KOG0192 Tyrosine kinase specific for activated (GT... 85 5e-16
YDL159w [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K) 84 7e-16
Hs7657214 [T] KOG0583 Serine/threonine protein kinase 84 9e-16
7298833 [KIT] KOG2345 Serine/threonine protein kinase/TGF-beta s... 83 1e-15
7292679 [G] KOG0599 Phosphorylase kinase gamma subunit 83 1e-15
YMR001c [D] KOG0575 Polo-like serine/threonine protein kinase 83 2e-15
At5g03730 [T] KOG0192 Tyrosine kinase specific for activated (GT... 83 2e-15
HsM4758524 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 82 3e-15
Hs7657335 [T] KOG0587 Traf2- and Nck-interacting kinase and rela... 82 3e-15
Hs5730055 [D] KOG0575 Polo-like serine/threonine protein kinase 82 3e-15
Hs22035606 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 82 3e-15
Hs22035604 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 82 3e-15
Hs22035602 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 82 3e-15
Hs13569922 [R] KOG0611 Predicted serine/threonine protein kinase 82 3e-15
At1g18390 [T] KOG1187 Serine/threonine protein kinase 82 3e-15
7302458 [T] KOG0574 STE20-like serine/threonine kinase MST 82 3e-15
Hs5454096 [T] KOG0574 STE20-like serine/threonine kinase MST 81 6e-15
7299322 [R] KOG0611 Predicted serine/threonine protein kinase 81 6e-15
At5g38210 [T] KOG1187 Serine/threonine protein kinase 81 7e-15
CE07285 [D] KOG0575 Polo-like serine/threonine protein kinase 80 1e-14
Hs4505373 [V] KOG1826 Ras GTPase activating protein RasGAP/neuro... 80 1e-14
At1g18160 [T] KOG0192 Tyrosine kinase specific for activated (GT... 80 1e-14
7296450 [D] KOG0575 Polo-like serine/threonine protein kinase 80 1e-14
7290841 [D] KOG0591 NIMA (never in mitosis)-related G2-specific ... 79 2e-14
CE23001 [R] KOG0589 Serine/threonine protein kinase 79 3e-14
CE22877 [D] KOG0575 Polo-like serine/threonine protein kinase 79 4e-14
7292249 [T] KOG0587 Traf2- and Nck-interacting kinase and relate... 79 4e-14
7302511 [T] KOG0576 Mitogen-activated protein kinase kinase kina... 78 5e-14
Hs5453882 [G] KOG0599 Phosphorylase kinase gamma subunit 78 6e-14
At5g58940 [T] KOG1187 Serine/threonine protein kinase 78 6e-14
At1g25390 [T] KOG1187 Serine/threonine protein kinase 78 6e-14
7302570 [R] KOG0586 Serine/threonine protein kinase 78 6e-14
Hs17445015 [KIT] KOG2345 Serine/threonine protein kinase/TGF-bet... 77 8e-14
At1g73660 [T] KOG0192 Tyrosine kinase specific for activated (GT... 77 8e-14
At1g08720 [T] KOG0192 Tyrosine kinase specific for activated (GT... 77 8e-14
Hs7661974 [T] KOG0583 Serine/threonine protein kinase 77 1e-13
Hs5454094 [T] KOG0574 STE20-like serine/threonine kinase MST 77 1e-13
Hs4505837 [KIT] KOG2345 Serine/threonine protein kinase/TGF-beta... 77 1e-13
Hs16178962 [T] KOG0574 STE20-like serine/threonine kinase MST 77 1e-13
CE00847 [T] KOG0583 Serine/threonine protein kinase 77 1e-13
7291778 [T] KOG0579 Ste20-like serine/threonine protein kinase 77 1e-13
CE27894_1 [R] KOG0589 Serine/threonine protein kinase 77 1e-13
YDR477w [T] KOG0583 Serine/threonine protein kinase 77 1e-13
At5g49470 [T] KOG0192 Tyrosine kinase specific for activated (GT... 77 1e-13
At3g19300 [T] KOG1187 Serine/threonine protein kinase 77 1e-13
Hs4507277_1 [R] KOG0589 Serine/threonine protein kinase 77 1e-13
At5g28290 [R] KOG0589 Serine/threonine protein kinase 76 2e-13
At4g24480 [T] KOG0192 Tyrosine kinase specific for activated (GT... 76 2e-13
SPAC2C4.14c [T] KOG0201 Serine/threonine protein kinase 76 2e-13
Hs6005810 [T] KOG0576 Mitogen-activated protein kinase kinase ki... 76 2e-13
At5g11850 [T] KOG0192 Tyrosine kinase specific for activated (GT... 76 2e-13
At3g04810 [R] KOG0589 Serine/threonine protein kinase 76 2e-13
Hs18552621 [R] KOG0597 Serine-threonine protein kinase FUSED 75 4e-13
CE27768 [R] KOG0586 Serine/threonine protein kinase 75 4e-13
CE23838 [R] KOG0586 Serine/threonine protein kinase 75 4e-13
At3g06620 [T] KOG0192 Tyrosine kinase specific for activated (GT... 75 4e-13
7297240_1 [T] KOG0587 Traf2- and Nck-interacting kinase and rela... 75 4e-13
At3g23000 [T] KOG0583 Serine/threonine protein kinase 75 5e-13
At1g67890 [T] KOG0192 Tyrosine kinase specific for activated (GT... 75 5e-13
Hs4505785 [G] KOG0599 Phosphorylase kinase gamma subunit 74 7e-13
At3g06640 [T] KOG0192 Tyrosine kinase specific for activated (GT... 74 7e-13
At3g25490 [T] KOG1187 Serine/threonine protein kinase 74 9e-13
At2g39110 [T] KOG1187 Serine/threonine protein kinase 74 9e-13
7297080 [T] KOG0583 Serine/threonine protein kinase 74 9e-13
At1g69220 [T] KOG0576 Mitogen-activated protein kinase kinase ki... 74 1e-12
CE28273 [T] KOG0587 Traf2- and Nck-interacting kinase and relate... 73 2e-12
CE25673 [T] KOG0587 Traf2- and Nck-interacting kinase and relate... 73 2e-12
CE25672 [T] KOG0587 Traf2- and Nck-interacting kinase and relate... 73 2e-12
At4g04700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 73 2e-12
At4g00330 [T] KOG1187 Serine/threonine protein kinase 73 2e-12
SPAC9G1.02 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 an... 73 2e-12
At5g58380 [T] KOG0583 Serine/threonine protein kinase 73 2e-12
YHR102w [T] KOG0201 Serine/threonine protein kinase 72 3e-12
At3g06630 [T] KOG0192 Tyrosine kinase specific for activated (GT... 72 3e-12
At1g61590 [T] KOG1187 Serine/threonine protein kinase 72 3e-12
SPAC1F5.09c [T] KOG0578 p21-activated serine/threonine protein k... 72 3e-12
ECU01g0630 [D] KOG0575 Polo-like serine/threonine protein kinase 72 3e-12
CE26649 [D] KOG0575 Polo-like serine/threonine protein kinase 72 3e-12
CE05507 [T] KOG0603 Ribosomal protein S6 kinase 72 3e-12
At4g14580 [T] KOG0583 Serine/threonine protein kinase 72 3e-12
Hs5174701 [T] KOG0579 Ste20-like serine/threonine protein kinase 72 4e-12
Hs15451902 [T] KOG0576 Mitogen-activated protein kinase kinase k... 72 4e-12
Hs14589909 [T] KOG0576 Mitogen-activated protein kinase kinase k... 72 4e-12
CE23702 [T] KOG4721 Serine/threonine protein kinase contains leu... 72 4e-12
7290150 [T] KOG0583 Serine/threonine protein kinase 72 4e-12
7290147 [T] KOG0583 Serine/threonine protein kinase 72 4e-12
CE27965 [T] KOG0574 STE20-like serine/threonine kinase MST 71 6e-12
CE27726 [T] KOG0574 STE20-like serine/threonine kinase MST 71 6e-12
CE27082 [T] KOG0574 STE20-like serine/threonine kinase MST 71 6e-12
CE07064 [T] KOG0574 STE20-like serine/threonine kinase MST 71 6e-12
At5g39440 [T] KOG0583 Serine/threonine protein kinase 71 6e-12
At1g53165 [T] KOG0201 Serine/threonine protein kinase 71 6e-12
CE16081 [T] KOG0583 Serine/threonine protein kinase 71 8e-12
CE28643 [T] KOG0583 Serine/threonine protein kinase 70 1e-11
CE07458 [T] KOG0583 Serine/threonine protein kinase 70 1e-11
At5g28680 [T] KOG1187 Serine/threonine protein kinase 70 1e-11
At2g38490 [T] KOG0583 Serine/threonine protein kinase 70 1e-11
SPCC320.12c [D] KOG0580 Serine/threonine protein kinase 70 1e-11
SPAC3H1.13 [KIT] KOG2345 Serine/threonine protein kinase/TGF-bet... 70 1e-11
Hs20070158 [T] KOG0201 Serine/threonine protein kinase 70 1e-11
Hs17933758 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 70 1e-11
7299536 [D] KOG0580 Serine/threonine protein kinase 70 1e-11
YAR019c [T] KOG0198 MEKK and related serine/threonine protein ki... 70 2e-11
HsM7657627 [D] KOG0575 Polo-like serine/threonine protein kinase 70 2e-11
HsM4507279 [D] KOG0580 Serine/threonine protein kinase 70 2e-11
HsM4505103 [R] KOG0586 Serine/threonine protein kinase 70 2e-11
Hs14042947 [T] KOG0583 Serine/threonine protein kinase 70 2e-11
At5g59700 [T] KOG1187 Serine/threonine protein kinase 70 2e-11
At5g11015 [T] KOG1187 Serine/threonine protein kinase 70 2e-11
At4g04740 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 70 2e-11
At3g46290 [T] KOG1187 Serine/threonine protein kinase 70 2e-11
At1g14370 [T] KOG1187 Serine/threonine protein kinase 70 2e-11
Hs7706601 [T] KOG0192 Tyrosine kinase specific for activated (GT... 69 2e-11
Hs19526767 [T] KOG0192 Tyrosine kinase specific for activated (G... 69 2e-11
At1g54510 [R] KOG0589 Serine/threonine protein kinase 69 2e-11
Hs20428779_1 [T] KOG0587 Traf2- and Nck-interacting kinase and r... 69 2e-11
SPAC644.06c [D] KOG0588 Serine/threonine protein kinase 69 3e-11
Hs21361433 [D] KOG0575 Polo-like serine/threonine protein kinase 69 3e-11
CE24994 [T] KOG0192 Tyrosine kinase specific for activated (GTP-... 69 3e-11
At2g23200 [T] KOG1187 Serine/threonine protein kinase 69 3e-11
7302464 [R] KOG0586 Serine/threonine protein kinase 69 3e-11
Hs4507275 [D] KOG0580 Serine/threonine protein kinase 69 4e-11
Hs20547806 [R] KOG0589 Serine/threonine protein kinase 69 4e-11
At5g35410 [T] KOG0583 Serine/threonine protein kinase 69 4e-11
At4g18700 [T] KOG0583 Serine/threonine protein kinase 69 4e-11
At3g15220 [T] KOG0201 Serine/threonine protein kinase 69 4e-11
Hs9845489 [R] KOG0586 Serine/threonine protein kinase 68 5e-11
Hs9845487 [R] KOG0586 Serine/threonine protein kinase 68 5e-11
Hs22062450 [R] KOG0586 Serine/threonine protein kinase 68 5e-11
CE21025 [D] KOG0580 Serine/threonine protein kinase 68 5e-11
At5g07070 [T] KOG0583 Serine/threonine protein kinase 68 5e-11
YOL100w [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 68 6e-11
Hs22035600 [T] KOG0576 Mitogen-activated protein kinase kinase k... 68 6e-11
Hs14770402 [R] KOG0586 Serine/threonine protein kinase 68 6e-11
CE21615 [T] KOG0578 p21-activated serine/threonine protein kinase 68 6e-11
At4g24400 [T] KOG0583 Serine/threonine protein kinase 68 6e-11
At3g19100 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 68 6e-11
YNL298w [T] KOG0578 p21-activated serine/threonine protein kinase 67 8e-11
SPCC576.15c [T] KOG0592 3-phosphoinositide-dependent protein kin... 67 8e-11
Hs5453964 [T] KOG0583 Serine/threonine protein kinase 67 8e-11
Hs4503787 [T] KOG0197 Tyrosine kinases 67 8e-11
Hs22043888 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 67 8e-11
At5g12180 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 67 8e-11
At1g48260 [T] KOG0583 Serine/threonine protein kinase 67 8e-11
7296128 [T] KOG0583 Serine/threonine protein kinase 67 8e-11
7291707 [T] KOG1152 Signal transduction serine/threonine kinase ... 67 8e-11
7290249 [R] KOG0586 Serine/threonine protein kinase 67 8e-11
Hs4826878 [T] KOG0582 Ste20-like serine/threonine protein kinase 67 1e-10
Hs20547878 [R] KOG0589 Serine/threonine protein kinase 67 1e-10
Hs19923407 [D] KOG0591 NIMA (never in mitosis)-related G2-specif... 67 1e-10
ECU02g0510 [D] KOG0596 Dual specificity; serine/threonine and ty... 67 1e-10
At5g35580 [T] KOG1187 Serine/threonine protein kinase 67 1e-10
At5g23580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 67 1e-10
At1g76040 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 67 1e-10
7293666 [D] KOG0575 Polo-like serine/threonine protein kinase 67 1e-10
SPBC4F6.06 [T] KOG0583 Serine/threonine protein kinase 67 1e-10
SPBC4C3.11 [T] KOG0592 3-phosphoinositide-dependent protein kina... 67 1e-10
Hs16507245 [T] KOG0583 Serine/threonine protein kinase 67 1e-10
CE29453 [T] KOG0192 Tyrosine kinase specific for activated (GTP-... 67 1e-10
CE20564 [T] KOG0578 p21-activated serine/threonine protein kinase 67 1e-10
CE05425 [T] KOG0578 p21-activated serine/threonine protein kinase 67 1e-10
At5g47850 [T] KOG1187 Serine/threonine protein kinase 67 1e-10
At3g17510 [T] KOG0583 Serine/threonine protein kinase 67 1e-10
At3g01490 [T] KOG0192 Tyrosine kinase specific for activated (GT... 67 1e-10
At2g45590 [T] KOG1187 Serine/threonine protein kinase 67 1e-10
At2g28940 [T] KOG1187 Serine/threonine protein kinase 67 1e-10
At2g23450 [T] KOG1187 Serine/threonine protein kinase 67 1e-10
At1g50230 [R] KOG0597 Serine-threonine protein kinase FUSED 67 1e-10
At1g30270 [T] KOG0583 Serine/threonine protein kinase 67 1e-10
At1g08650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 67 1e-10
CE06635 [Z] KOG0613 Projectin/twitchin and related proteins 66 2e-10
CE06634 [Z] KOG0613 Projectin/twitchin and related proteins 66 2e-10
At5g19360 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 66 2e-10
At4g38230 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 66 2e-10
At3g24540 [T] KOG1187 Serine/threonine protein kinase 66 2e-10
At2g02800 [T] KOG1187 Serine/threonine protein kinase 66 2e-10
Hs8393810_1 [T] KOG0587 Traf2- and Nck-interacting kinase and re... 66 2e-10
Hs20544910_1 [T] KOG0587 Traf2- and Nck-interacting kinase and r... 66 2e-10
YDR523c [T] KOG0201 Serine/threonine protein kinase 66 2e-10
HsM4759010 [T] KOG0576 Mitogen-activated protein kinase kinase k... 66 2e-10
Hs8923922 [R] KOG0586 Serine/threonine protein kinase 66 2e-10
Hs7661994 [T] KOG0579 Ste20-like serine/threonine protein kinase 66 2e-10
Hs4758700 [T] KOG0604 MAP kinase-activated protein kinase 2 66 2e-10
Hs19923464 [T] KOG0577 Serine/threonine protein kinase 66 2e-10
CE03103 [KIT] KOG2345 Serine/threonine protein kinase/TGF-beta s... 66 2e-10
At5g04510 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 66 2e-10
At4g14480 [T] KOG0582 Ste20-like serine/threonine protein kinase 66 2e-10
At3g20860 [R] KOG0589 Serine/threonine protein kinase 66 2e-10
At2g11520 [T] KOG1187 Serine/threonine protein kinase 66 2e-10
Hs4759178 [D] KOG0580 Serine/threonine protein kinase 65 3e-10
Hs4758016 [D] KOG0575 Polo-like serine/threonine protein kinase 65 3e-10
Hs4507273 [D] KOG0580 Serine/threonine protein kinase 65 3e-10
CE12472 [T] KOG0200 Fibroblast/platelet-derived growth factor re... 65 3e-10
At4g35780 [T] KOG0192 Tyrosine kinase specific for activated (GT... 65 3e-10
At2g31010 [T] KOG0192 Tyrosine kinase specific for activated (GT... 65 3e-10
At1g24030 [T] KOG1187 Serine/threonine protein kinase 65 3e-10
7298926 [T] KOG0578 p21-activated serine/threonine protein kinase 65 3e-10
SPBC21.06c [T] KOG0198 MEKK and related serine/threonine protein... 65 4e-10
SPBC17F3.02 [T] KOG0201 Serine/threonine protein kinase 65 4e-10
Hs7382496 [T] KOG0578 p21-activated serine/threonine protein kinase 65 4e-10
Hs4505599 [T] KOG0578 p21-activated serine/threonine protein kinase 65 4e-10
Hs14771959 [T] KOG0578 p21-activated serine/threonine protein ki... 65 4e-10
CE26212 [T] KOG0582 Ste20-like serine/threonine protein kinase 65 4e-10
At5g03320 [T] KOG1187 Serine/threonine protein kinase 65 4e-10
At5g01810 [T] KOG0583 Serine/threonine protein kinase 65 4e-10
At3g56760 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 65 4e-10
At1g49730 [T] KOG1187 Serine/threonine protein kinase 65 4e-10
Hs4758128_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 65 4e-10
SPCC1259.13 [D] KOG0590 Checkpoint kinase and related serine/thr... 65 5e-10
Hs4506889 [T] KOG1006 Mitogen-activated protein kinase (MAPK) ki... 65 5e-10
Hs21361133 [R] KOG0586 Serine/threonine protein kinase 65 5e-10
Hs13899225 [R] KOG0586 Serine/threonine protein kinase 65 5e-10
At3g10540 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 65 5e-10
At3g09830 [T] KOG1187 Serine/threonine protein kinase 65 5e-10
At2g17290 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 65 5e-10
At1g53570 [T] KOG0198 MEKK and related serine/threonine protein ... 65 5e-10
At1g29230 [T] KOG0583 Serine/threonine protein kinase 65 5e-10
7303019 [Z] KOG0613 Projectin/twitchin and related proteins 65 5e-10
Hs5453966 [T] KOG0583 Serine/threonine protein kinase 64 7e-10
Hs4557511 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 64 7e-10
At3g29160 [T] KOG0583 Serine/threonine protein kinase 64 7e-10
At3g10660 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 64 7e-10
At2g34180 [T] KOG0583 Serine/threonine protein kinase 64 7e-10
YDR122w [T] KOG0583 Serine/threonine protein kinase 64 9e-10
HsM4826916 [D] KOG0575 Polo-like serine/threonine protein kinase 64 9e-10
HsM4506099 [T] KOG0984 Mitogen-activated protein kinase (MAPK) k... 64 9e-10
Hs21618351 [T] KOG0984 Mitogen-activated protein kinase (MAPK) k... 64 9e-10
Hs21618349 [T] KOG0984 Mitogen-activated protein kinase (MAPK) k... 64 9e-10
Hs21618347 [T] KOG0984 Mitogen-activated protein kinase (MAPK) k... 64 9e-10
Hs21359873 [D] KOG0575 Polo-like serine/threonine protein kinase 64 9e-10
CE28479 [T] KOG0583 Serine/threonine protein kinase 64 9e-10
At5g45810 [T] KOG0583 Serine/threonine protein kinase 64 9e-10
At3g59110 [T] KOG1187 Serine/threonine protein kinase 64 9e-10
At2g45490 [D] KOG0580 Serine/threonine protein kinase 64 9e-10
At2g35890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 64 9e-10
At2g26980 [T] KOG0583 Serine/threonine protein kinase 64 9e-10
At1g12680 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 64 9e-10
YGL179c [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 64 1e-09
CE24941 [T] KOG0983 Mitogen-activated protein kinase (MAPK) kina... 64 1e-09
At5g54380 [T] KOG1187 Serine/threonine protein kinase 64 1e-09
At3g13530 [T] KOG0198 MEKK and related serine/threonine protein ... 64 1e-09
At3g04690 [T] KOG1187 Serine/threonine protein kinase 64 1e-09
At1g49580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 64 1e-09
Hs19311016_1 [R] KOG0589 Serine/threonine protein kinase 64 1e-09
YCR073c [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and r... 63 2e-09
SPAC23H4.02 [T] KOG0583 Serine/threonine protein kinase 63 2e-09
Hs5031975 [T] KOG0578 p21-activated serine/threonine protein kinase 63 2e-09
Hs4505601 [T] KOG0578 p21-activated serine/threonine protein kinase 63 2e-09
Hs15011880 [T] KOG0201 Serine/threonine protein kinase 63 2e-09
ECU08g1480 [R] KOG0586 Serine/threonine protein kinase 63 2e-09
CE15235 [R] KOG0589 Serine/threonine protein kinase 63 2e-09
At5g39000 [T] KOG1187 Serine/threonine protein kinase 63 2e-09
At4g36070 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 63 2e-09
At1g62400 [T] KOG0192 Tyrosine kinase specific for activated (GT... 63 2e-09
YBR274w [D] KOG0590 Checkpoint kinase and related serine/threoni... 63 2e-09
Hs7019543 [T] KOG0582 Ste20-like serine/threonine protein kinase 63 2e-09
At4g29810 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 63 2e-09
At4g02010 [T] KOG1187 Serine/threonine protein kinase 63 2e-09
At3g50530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 63 2e-09
At3g20410 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 63 2e-09
At2g17890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 63 2e-09
7298004 [G] KOG0658 Glycogen synthase kinase-3 63 2e-09
Hs22065797 [T] KOG0577 Serine/threonine protein kinase 62 3e-09
Hs19424132 [D] KOG0591 NIMA (never in mitosis)-related G2-specif... 62 3e-09
CE24761 [D] KOG0580 Serine/threonine protein kinase 62 3e-09
CE03584 [T] KOG0607 MAP kinase-interacting kinase and related se... 62 3e-09
At5g02070 [T] KOG1187 Serine/threonine protein kinase 62 3e-09
At4g35310 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 62 3e-09
At4g30960 [T] KOG0583 Serine/threonine protein kinase 62 3e-09
At4g24100 [T] KOG0582 Ste20-like serine/threonine protein kinase 62 3e-09
At4g23650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 62 3e-09
At3g50310 [T] KOG0198 MEKK and related serine/threonine protein ... 62 3e-09
At1g52290 [T] KOG1187 Serine/threonine protein kinase 62 3e-09
At1g49270 [T] KOG1187 Serine/threonine protein kinase 62 3e-09
YLR096w [T] KOG0583 Serine/threonine protein kinase 62 4e-09
YKL101w [D] KOG0588 Serine/threonine protein kinase 62 4e-09
SPCC74.03c [T] KOG0583 Serine/threonine protein kinase 62 4e-09
Hs4505811 [T] KOG0583 Serine/threonine protein kinase 62 4e-09
Hs14589904 [T] KOG0604 MAP kinase-activated protein kinase 2 62 4e-09
Hs10863901 [T] KOG0604 MAP kinase-activated protein kinase 2 62 4e-09
ECU07g0520 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 62 4e-09
ECU07g0360 [D] KOG0580 Serine/threonine protein kinase 62 4e-09
ECU03g0980 [T] KOG0583 Serine/threonine protein kinase 62 4e-09
At4g04720 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 62 4e-09
At4g04710 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 62 4e-09
At3g01090 [T] KOG0583 Serine/threonine protein kinase 62 4e-09
At1g33260 [T] KOG1187 Serine/threonine protein kinase 62 4e-09
7303211 [T] KOG4717 Serine/threonine protein kinase 62 4e-09
YDR490c [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 62 5e-09
At5g66790 [T] KOG1187 Serine/threonine protein kinase 62 5e-09
At1g14000 [T] KOG0192 Tyrosine kinase specific for activated (GT... 62 5e-09
7299438 [R] KOG0586 Serine/threonine protein kinase 62 5e-09
Hs4826684_1 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 62 5e-09
Hs4502553 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 61 6e-09
Hs22057171 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 61 6e-09
CE28218 [D] KOG0588 Serine/threonine protein kinase 61 6e-09
CE17284 [T] KOG0583 Serine/threonine protein kinase 61 6e-09
At5g47070 [T] KOG1187 Serine/threonine protein kinase 61 6e-09
At5g25110 [T] KOG0583 Serine/threonine protein kinase 61 6e-09
At4g32710 [T] KOG1187 Serine/threonine protein kinase 61 6e-09
At3g51990 [T] KOG1187 Serine/threonine protein kinase 61 6e-09
At2g41140 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 61 6e-09
At1g69910 [T] KOG1187 Serine/threonine protein kinase 61 6e-09
7300224 [T] KOG0201 Serine/threonine protein kinase 61 6e-09
7299437 [R] KOG0586 Serine/threonine protein kinase 61 6e-09
7292830 [T] KOG0984 Mitogen-activated protein kinase (MAPK) kina... 61 6e-09
SPAC1805.01c [T] KOG1152 Signal transduction serine/threonine ki... 61 8e-09
CE28842 [T] KOG4250 TANK binding protein kinase TBK1 61 8e-09
CE25046 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 61 8e-09
At4g10390 [T] KOG1187 Serine/threonine protein kinase 61 8e-09
At3g51550 [T] KOG1187 Serine/threonine protein kinase 61 8e-09
7303111 [T] KOG0695 Serine/threonine protein kinase 61 8e-09
7301972 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 61 8e-09
SPBC32C12.03c [T] KOG0583 Serine/threonine protein kinase 60 1e-08
Hs4826776 [T] KOG0197 Tyrosine kinases 60 1e-08
Hs4759052 [T] KOG0603 Ribosomal protein S6 kinase 60 1e-08
At5g58950 [T] KOG0192 Tyrosine kinase specific for activated (GT... 60 1e-08
At5g57630 [T] KOG0583 Serine/threonine protein kinase 60 1e-08
At5g45820 [T] KOG0583 Serine/threonine protein kinase 60 1e-08
At5g42440 [T] KOG1187 Serine/threonine protein kinase 60 1e-08
At5g14720 [T] KOG0582 Ste20-like serine/threonine protein kinase 60 1e-08
At5g04870 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 60 1e-08
At3g46930 [T] KOG0192 Tyrosine kinase specific for activated (GT... 60 1e-08
At2g46700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 60 1e-08
At1g50700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 60 1e-08
7304283 [Z] KOG0613 Projectin/twitchin and related proteins 60 1e-08
7300435 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and r... 60 1e-08
Hs4759044 [T] KOG0612 Rho-associated coiled-coil containing prot... 60 1e-08
Hs4758696 [T] KOG4721 Serine/threonine protein kinase contains l... 60 1e-08
Hs21361643 [T] KOG4717 Serine/threonine protein kinase 60 1e-08
Hs20536595 [T] KOG0612 Rho-associated coiled-coil containing pro... 60 1e-08
CE28674 [T] KOG0201 Serine/threonine protein kinase 60 1e-08
CE07510 [T] KOG0201 Serine/threonine protein kinase 60 1e-08
At4g10730 [T] KOG0582 Ste20-like serine/threonine protein kinase 60 1e-08
At3g59830 [T] KOG0192 Tyrosine kinase specific for activated (GT... 60 1e-08
At2g42960 [T] KOG1187 Serine/threonine protein kinase 60 1e-08
At1g01140 [T] KOG0583 Serine/threonine protein kinase 60 1e-08
7292656 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 60 1e-08
YCL024w [T] KOG0583 Serine/threonine protein kinase 60 2e-08
SPCC297.03 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 60 2e-08
Hs4885583 [T] KOG0612 Rho-associated coiled-coil containing prot... 60 2e-08
CE28702 [T] KOG4250 TANK binding protein kinase TBK1 60 2e-08
CE07599 [T] KOG0576 Mitogen-activated protein kinase kinase kina... 60 2e-08
At2g21480 [T] KOG1187 Serine/threonine protein kinase 60 2e-08
At1g70460 [T] KOG1187 Serine/threonine protein kinase 60 2e-08
7301213 [R] KOG0589 Serine/threonine protein kinase 60 2e-08
7293601 [T] KOG0577 Serine/threonine protein kinase 60 2e-08
YOR233w [T] KOG0583 Serine/threonine protein kinase 59 2e-08
SPAC57A10.02 [D] KOG0588 Serine/threonine protein kinase 59 2e-08
HsM5454174 [T] KOG0201 Serine/threonine protein kinase 59 2e-08
Hs21361358 [T] KOG0201 Serine/threonine protein kinase 59 2e-08
At5g40440 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 59 2e-08
At5g38990 [T] KOG1187 Serine/threonine protein kinase 59 2e-08
At5g35960 [T] KOG1187 Serine/threonine protein kinase 59 2e-08
At4g35600 [T] KOG1187 Serine/threonine protein kinase 59 2e-08
At2g31800 [T] KOG0192 Tyrosine kinase specific for activated (GT... 59 2e-08
At1g61950 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 59 2e-08
7302861 [T] KOG0696 Serine/threonine protein kinase 59 2e-08
7298652 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 59 2e-08
HsM4758892 [J] KOG1033 eIF-2alpha kinase PEK/EIF2AK3 59 3e-08
Hs7706401 [T] KOG0577 Serine/threonine protein kinase 59 3e-08
Hs5803125 [T] KOG0583 Serine/threonine protein kinase 59 3e-08
Hs4759208 [T] KOG0577 Serine/threonine protein kinase 59 3e-08
Hs4758194 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 59 3e-08
Hs4757868 [T] KOG0193 Serine/threonine protein kinase RAF 59 3e-08
Hs21361155 [J] KOG1033 eIF-2alpha kinase PEK/EIF2AK3 59 3e-08
Hs14728804 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 59 3e-08
Hs13649368 [T] KOG0583 Serine/threonine protein kinase 59 3e-08
At3g07980 [T] KOG0198 MEKK and related serine/threonine protein ... 59 3e-08
At2g38910 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 59 3e-08
At2g17700 [T] KOG0192 Tyrosine kinase specific for activated (GT... 59 3e-08
At1g09000 [T] KOG0198 MEKK and related serine/threonine protein ... 59 3e-08
7293496 [R] KOG0597 Serine-threonine protein kinase FUSED 59 3e-08
YJL187c [D] KOG0601 Cyclin-dependent kinase WEE1 59 4e-08
Hs22065589 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 59 4e-08
Hs22044030 [T] KOG0192 Tyrosine kinase specific for activated (G... 59 4e-08
Hs20479818 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 59 4e-08
CE09248 [T] KOG0200 Fibroblast/platelet-derived growth factor re... 59 4e-08
CE06504 [T] KOG0194 Protein tyrosine kinase 59 4e-08
CE05780 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 59 4e-08
At5g66210 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 59 4e-08
At2g05940 [T] KOG1187 Serine/threonine protein kinase 59 4e-08
At1g29720 [T] KOG1187 Serine/threonine protein kinase 59 4e-08
7299057 [T] KOG1006 Mitogen-activated protein kinase (MAPK) kina... 59 4e-08
7297166 [T] KOG1345 Serine/threonine kinase 59 4e-08
Hs6005922_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 59 4e-08
CE18058_1 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 59 4e-08
YJL095w [T] KOG0198 MEKK and related serine/threonine protein ki... 58 5e-08
YHR030c [T] KOG0660 Mitogen-activated protein kinase 58 5e-08
SPCC162.10 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 58 5e-08
Hs4505831 [T] KOG0612 Rho-associated coiled-coil containing prot... 58 5e-08
Hs4503095 [TDK] KOG0668 Casein kinase II alpha subunit 58 5e-08
Hs20545357 [T] KOG0583 Serine/threonine protein kinase 58 5e-08
Hs10334852 [T] KOG0612 Rho-associated coiled-coil containing pro... 58 5e-08
CE27573 [T] KOG0198 MEKK and related serine/threonine protein ki... 58 5e-08
CE07737 [T] KOG0198 MEKK and related serine/threonine protein ki... 58 5e-08
CE02377 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 58 5e-08
At4g39110 [T] KOG1187 Serine/threonine protein kinase 58 5e-08
At4g14780 [T] KOG0192 Tyrosine kinase specific for activated (GT... 58 5e-08
At3g55450 [T] KOG1187 Serine/threonine protein kinase 58 5e-08
At3g49370 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 58 5e-08
At2g42630 [T] KOG0192 Tyrosine kinase specific for activated (GT... 58 5e-08
7302908 [R] KOG0594 Protein kinase PCTAIRE and related kinases 58 5e-08
7294217 [D] KOG0588 Serine/threonine protein kinase 58 5e-08
7291742_1 [T] KOG0612 Rho-associated coiled-coil containing prot... 58 5e-08
SPCC70.05c [D] KOG0590 Checkpoint kinase and related serine/thre... 58 7e-08
HsM4506035 [T] KOG0604 MAP kinase-activated protein kinase 2 58 7e-08
Hs4502435 [T] KOG0197 Tyrosine kinases 58 7e-08
Hs21237768 [T] KOG0604 MAP kinase-activated protein kinase 2 58 7e-08
Hs21237765 [T] KOG0604 MAP kinase-activated protein kinase 2 58 7e-08
At5g50000 [T] KOG0192 Tyrosine kinase specific for activated (GT... 58 7e-08
At5g10930 [T] KOG0583 Serine/threonine protein kinase 58 7e-08
At4g32830 [D] KOG0580 Serine/threonine protein kinase 58 7e-08
At4g21940 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 58 7e-08
At3g18810 [T] KOG1187 Serine/threonine protein kinase 58 7e-08
At3g04530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 58 7e-08
At2g29000 [T] KOG1187 Serine/threonine protein kinase 58 7e-08
At2g28590 [T] KOG1187 Serine/threonine protein kinase 58 7e-08
At1g35670 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 58 7e-08
7295585 [T] KOG0192 Tyrosine kinase specific for activated (GTP-... 58 7e-08
Hs16357474_1 [T] KOG0612 Rho-associated coiled-coil containing p... 58 7e-08
YKL048c [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 57 9e-08
YHL007c [T] KOG0578 p21-activated serine/threonine protein kinase 57 9e-08
YDR507c [D] KOG0588 Serine/threonine protein kinase 57 9e-08
SPBC409.07c [T] KOG0581 Mitogen-activated protein kinase kinase ... 57 9e-08
HsM5454184 [T] KOG4721 Serine/threonine protein kinase contains ... 57 9e-08
HsM4505191 [T] KOG0607 MAP kinase-interacting kinase and related... 57 9e-08
Hs4506103 [J] KOG1033 eIF-2alpha kinase PEK/EIF2AK3 57 9e-08
Hs21735552 [T] KOG4721 Serine/threonine protein kinase contains ... 57 9e-08
Hs18602554 [T] KOG0578 p21-activated serine/threonine protein ki... 57 9e-08
CE11916 [T] KOG0612 Rho-associated coiled-coil containing protei... 57 9e-08
At5g66850 [T] KOG0198 MEKK and related serine/threonine protein ... 57 9e-08
At5g01850 [T] KOG0192 Tyrosine kinase specific for activated (GT... 57 9e-08
7295431 [D] KOG0601 Cyclin-dependent kinase WEE1 57 9e-08
YPL209c [D] KOG0580 Serine/threonine protein kinase 57 1e-07
YOL045w [T] KOG1152 Signal transduction serine/threonine kinase ... 57 1e-07
Hs6382062 [T] KOG4278 Protein tyrosine kinase 57 1e-07
Hs6382060 [T] KOG4278 Protein tyrosine kinase 57 1e-07
Hs4505153 [T] KOG0198 MEKK and related serine/threonine protein ... 57 1e-07
Hs4504803 [T] KOG0197 Tyrosine kinases 57 1e-07
Hs14670383 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 57 1e-07
CE16527 [T] KOG1006 Mitogen-activated protein kinase (MAPK) kina... 57 1e-07
CE04724 [T] KOG0983 Mitogen-activated protein kinase (MAPK) kina... 57 1e-07
At3g24400 [T] KOG1187 Serine/threonine protein kinase 57 1e-07
At3g06030 [T] KOG0198 MEKK and related serine/threonine protein ... 57 1e-07
At2g39360 [T] KOG1187 Serine/threonine protein kinase 57 1e-07
At2g25880 [D] KOG0580 Serine/threonine protein kinase 57 1e-07
At1g28390 [T] KOG1187 Serine/threonine protein kinase 57 1e-07
YKL161c [T] KOG0660 Mitogen-activated protein kinase 57 1e-07
SPCC18B5.11c [D] KOG0615 Serine/threonine protein kinase Chk2 an... 57 1e-07
Hs9910476 [T] KOG0578 p21-activated serine/threonine protein kinase 57 1e-07
Hs4507831 [OUT] KOG0595 Serine/threonine-protein kinase involved... 57 1e-07
Hs4506537 [T] KOG0192 Tyrosine kinase specific for activated (GT... 57 1e-07
CE07905 [T] KOG0579 Ste20-like serine/threonine protein kinase 57 1e-07
CE02586 [T] KOG0696 Serine/threonine protein kinase 57 1e-07
At5g61350 [T] KOG1187 Serine/threonine protein kinase 57 1e-07
At4g34500 [T] KOG1187 Serine/threonine protein kinase 57 1e-07
At2g30360 [T] KOG0583 Serine/threonine protein kinase 57 1e-07
At1g63700 [T] KOG0198 MEKK and related serine/threonine protein ... 57 1e-07
7299793 [T] KOG0583 Serine/threonine protein kinase 57 1e-07
7297611 [T] KOG0614 cGMP-dependent protein kinase 57 1e-07
At1g20650_2 [T] KOG1187 Serine/threonine protein kinase 57 1e-07
YOL113w [T] KOG0578 p21-activated serine/threonine protein kinase 56 2e-07
YAL017w [T] KOG1152 Signal transduction serine/threonine kinase ... 56 2e-07
Hs4826948 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 56 2e-07
At5g24430 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 56 2e-07
At4g08500 [T] KOG0198 MEKK and related serine/threonine protein ... 56 2e-07
At2g31500 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 56 2e-07
At2g24360 [T] KOG0192 Tyrosine kinase specific for activated (GT... 56 2e-07
At1g78530 [T] KOG1187 Serine/threonine protein kinase 56 2e-07
At1g54960 [T] KOG0198 MEKK and related serine/threonine protein ... 56 2e-07
At1g51870 [T] KOG1187 Serine/threonine protein kinase 56 2e-07
At1g17910 [T] KOG1187 Serine/threonine protein kinase 56 2e-07
At1g11050 [T] KOG1187 Serine/threonine protein kinase 56 2e-07
At1g07870 [T] KOG1187 Serine/threonine protein kinase 56 2e-07
7302478 [T] KOG4257 Focal adhesion tyrosine kinase FAK contains ... 56 2e-07
>YBR059c [T] KOG1989 ARK protein kinase family
Length = 1108
Score = 536 bits (1382), Expect = e-152
Identities = 265/396 (66%), Positives = 318/396 (79%), Gaps = 11/396 (2%)
Query: 30 SPNTQVVVGTHRCEILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVI 89
+P V VGTH+ E++ +LAEGGFA IY VKFLE NE D S LK GD+ACLKRV+
Sbjct: 23 TPGHIVCVGTHKVEVVNYLAEGGFAQIYVVKFLEYLNEFD-NTASVPLKIGDVACLKRVL 81
Query: 90 VPDENGLNELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLD 149
V DENGLNE+RNEVE MK+L+G+PNIVQY+DSNASR DG GFE+LLLMELCP KSLLD
Sbjct: 82 VQDENGLNEMRNEVEVMKKLKGAPNIVQYFDSNASRRRDGVQGFEVLLLMELCPNKSLLD 141
Query: 150 YMNNKLATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFG 209
YMN +L+TKLTEAEI+KIMYDV+ +I+QMHYLP LIHRDIKIENVLVD +NFKL DFG
Sbjct: 142 YMNQRLSTKLTEAEIVKIMYDVALSISQMHYLPVSLIHRDIKIENVLVDAKNNFKLADFG 201
Query: 210 STSMCFPIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKL 269
STS CFPIV+THQDIA+LT NIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALG+FLYKL
Sbjct: 202 STSTCFPIVTTHQDIALLTQNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGVFLYKL 261
Query: 270 LFYTTPFELTGQFAILHSKYEIPQNGYSSKLINLIIIMLAENPSLRPNIYQVMHHVCSIL 329
LF+TTPFE+TGQFAILHSKYE P N YSSKLINLIIIMLAENP+LRPNIYQV++H+C IL
Sbjct: 262 LFFTTPFEMTGQFAILHSKYEFPVNKYSSKLINLIIIMLAENPNLRPNIYQVLYHLCEIL 321
Query: 330 KCDVPFTDKYELGPYDFAKYSQYHLKLQQIQYQMFEL-----YKNEKVTSGDVDKLNDLF 384
+VP DKY G Y+F+KY+Q+ KLQ +Q QM++L +N K++ + + LND+F
Sbjct: 322 NVEVPIEDKYAEGAYNFSKYTQFQNKLQNVQLQMYQLQQKKIMQNNKLSDSEENLLNDMF 381
Query: 385 IQNFEIAPKQPID-----KGIGSVDQQEAPEDLETD 415
+ +FEI+ K P++ + + Q ++LE +
Sbjct: 382 LSSFEISSKLPMNASDGHAAVSRIPSQNVGQELEEE 417
>YIL095w [T] KOG1989 ARK protein kinase family
Length = 810
Score = 278 bits (710), Expect = 3e-74
Identities = 150/319 (47%), Positives = 200/319 (62%), Gaps = 12/319 (3%)
Query: 24 PNSHLLSPNTQVVVGTHRCEILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIA 83
P L P T + VG+H +I+++L GGFA +Y + +A +IA
Sbjct: 4 PQISLYEPGTILTVGSHHAKIIKYLTSGGFAQVYTAEISPPDPYSNA----------NIA 53
Query: 84 CLKRVIVPDENGLNELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCP 143
CLKRVIVP + GLN LR EV+ MK LR + ++V Y DS+A+R +G +E+ +LME C
Sbjct: 54 CLKRVIVPHKQGLNTLRAEVDAMKLLRNNKHVVSYIDSHAARSVNGI-AYEVFVLMEFCE 112
Query: 144 KKSLLDYMNNKLATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNF 203
+ L+D+MN +L +L E+EIL+IM I MH L PLIHRDIKIENVL+ D +
Sbjct: 113 RGGLIDFMNTRLQNRLQESEILEIMSQTVQGITAMHALQPPLIHRDIKIENVLISHDGLY 172
Query: 204 KLCDFGSTSMCFPIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALG 263
K+CDFGS S Q+ + ++I +TT QYRSPEMIDLYR LPI+EKSDIWALG
Sbjct: 173 KVCDFGSVSGVIRPPRNTQEFNYVQHDILTNTTAQYRSPEMIDLYRGLPIDEKSDIWALG 232
Query: 264 IFLYKLLFYTTPFELTGQFAILHSKYEIPQ-NGYSSKLINLIIIMLAENPSLRPNIYQVM 322
+FLYK+ +YTTPFE +G+ ILH++Y+ P YS +L NLI +ML E PS RPNI QV+
Sbjct: 233 VFLYKICYYTTPFEKSGEAGILHARYQYPSFPQYSDRLKNLIRLMLMEAPSQRPNICQVL 292
Query: 323 HHVCSILKCDVPFTDKYEL 341
V + P + Y L
Sbjct: 293 EEVSRLQNKPCPIRNFYLL 311
>YNL020c [T] KOG1989 ARK protein kinase family
Length = 638
Score = 265 bits (677), Expect = 2e-70
Identities = 141/306 (46%), Positives = 194/306 (63%), Gaps = 11/306 (3%)
Query: 33 TQVVVGTHRCEILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPD 92
TQ+ VG+H+ EI+++L GGFA +Y L N D +S +ACLKRVIVPD
Sbjct: 13 TQLTVGSHQVEIIKYLTSGGFAQVYSA----LINPPDPHSNSS------VACLKRVIVPD 62
Query: 93 ENGLNELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMN 152
+ LN LR EV+ M+ L+ + +V Y DS+A++ + +E+ +LME C + L+D+MN
Sbjct: 63 KPSLNTLRAEVDAMRLLKNNRYVVSYIDSHAAKAMLHNGSYEVFVLMEYCERGGLIDFMN 122
Query: 153 NKLATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTS 212
+L +L E EIL+IM V+ +A MH L PLIHRDIKIENVL+ ++ +KLCDFGS
Sbjct: 123 TRLQNRLHEFEILQIMSQVTQGVAAMHALQPPLIHRDIKIENVLISANNEYKLCDFGSVC 182
Query: 213 MCFPIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFY 272
Q+++ + +I +TT QYRSPEMID +R LPI+EKSDIWALGIFLYKL +Y
Sbjct: 183 GIIRPPRNSQELSYVQQDILKNTTAQYRSPEMIDTFRGLPIDEKSDIWALGIFLYKLCYY 242
Query: 273 TTPFELTGQFAILHSKYEIP-QNGYSSKLINLIIIMLAENPSLRPNIYQVMHHVCSILKC 331
TTPFE G AIL K+E P YS +L LI +L ++P RPN+YQ++ + +
Sbjct: 243 TTPFEKGGDLAILSGKFEFPLYPNYSEQLKGLIRDILVQDPRHRPNVYQLLKRISIMQNV 302
Query: 332 DVPFTD 337
P D
Sbjct: 303 PCPIND 308
>SPBC557.04 [T] KOG1989 ARK protein kinase family
Length = 872
Score = 250 bits (639), Expect = 5e-66
Identities = 139/314 (44%), Positives = 193/314 (61%), Gaps = 15/314 (4%)
Query: 29 LSPNTQVVVGTHRCEILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRV 88
L ++ V+G + I +++AEGGF+++Y V+ +SK + A LKR+
Sbjct: 12 LLAGSKFVIGKYNVTIEKYIAEGGFSHVYLVQ-----------TNSKTDGSPITAVLKRM 60
Query: 89 IVPDENGLNELRNEVETMKQLRGSPNIVQYYDSNAS--RHPDGSPGFEILLLMELCPKKS 146
PDEN L ++ E+ETM+ L+ +P++V Y DS + GFEILLLME C
Sbjct: 61 YSPDENALRFVKTEIETMELLKSNPHVVSYIDSCIFPLEKAGVNTGFEILLLMEYCAGGG 120
Query: 147 LLDYMNNKLATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLC 206
L+D+MN +L T+L+E E+LKI+ D+ +A +HYL PLIHRD+K+ENVL+ + FKLC
Sbjct: 121 LIDFMNQRLQTRLSEHEVLKIISDIVQGVASLHYLRPPLIHRDLKVENVLLSFN-TFKLC 179
Query: 207 DFGSTSMCFPIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFL 266
DFGS + +I L +I TT QYR+PEMI+LY L I+EKSD+WALG+ L
Sbjct: 180 DFGSVTEPMHAAENSSEIQALEKSINTFTTYQYRAPEMINLYSGLGIDEKSDMWALGVLL 239
Query: 267 YKLLFYTTPFELTGQFAILHSKYEIPQ-NGYSSKLINLIIIMLAENPSLRPNIYQVMHHV 325
YKL +YTTPFE G AIL + Y P YS L N+II +L NP LRPNI+Q+M +
Sbjct: 240 YKLCYYTTPFETQGPNAILTASYSFPPFPPYSHSLKNVIIALLQPNPCLRPNIFQLMCEI 299
Query: 326 CSILKCDVPFTDKY 339
C + +PF D Y
Sbjct: 300 CRLRGTALPFRDIY 313
>SPBC6B1.02 [T] KOG1989 ARK protein kinase family
Length = 953
Score = 243 bits (620), Expect = 9e-64
Identities = 138/327 (42%), Positives = 190/327 (57%), Gaps = 20/327 (6%)
Query: 33 TQVVVGTHRCEILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPD 92
T++ VG+H I +L+EGGF+++Y LL+ LKR+ VPD
Sbjct: 48 TKIQVGSHSVIIQRYLSEGGFSHVYLA----------------LLENEKPFVLKRIYVPD 91
Query: 93 ENGLNELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMN 152
+ L + E+ETMK+L+G +IV Y DS+A + +E+ LLME C L+D+MN
Sbjct: 92 KTALQLVHGEIETMKRLKGHRHIVNYIDSSAL-YSKSENRYEVYLLMEFCAGGGLIDFMN 150
Query: 153 NKLATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTS 212
+L +LTE EILKI+ DV +A+A MHYL PLIHRD+KIENVL+ +++KLCDFGS
Sbjct: 151 TRLQHRLTEGEILKILADVCDAVAAMHYLDPPLIHRDLKIENVLLVAPNSYKLCDFGSAC 210
Query: 213 MCFPIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFY 272
+T I L NI +TTPQYR+PEMID+ R I+EKSDIWA+G+ YKL +Y
Sbjct: 211 EPLAPATTPDTIMFLEQNIAAYTTPQYRAPEMIDINRRQGIDEKSDIWAIGVLAYKLCYY 270
Query: 273 TTPFELTGQFAILHSKYEIPQ-NGYSSKLINLIIIMLAENPSLRPNIYQVMHHVCSILKC 331
TTPFE G AIL + + P YS ++ I L E PS RPNIYQ + + +
Sbjct: 271 TTPFEQVGNSAILKASFSFPPFPRYSDRMKRFIATCLQEQPSHRPNIYQTLKEIMEMQGT 330
Query: 332 DVPFTDKYELGPYDFAKYSQYHLKLQQ 358
+ D Y G + + Y+ LQ+
Sbjct: 331 PLKLPDVY--GGVNASTYNPPRAPLQR 355
>SPCP1E11.02 [T] KOG1989 ARK protein kinase family
Length = 650
Score = 213 bits (543), Expect = 7e-55
Identities = 127/315 (40%), Positives = 170/315 (53%), Gaps = 15/315 (4%)
Query: 26 SHLLSPNTQVVVGTHRCEILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACL 85
S LL V + +LAEGGF+++Y V+ + K A L
Sbjct: 17 SGLLPVGFSCTVEKFSVTVKRYLAEGGFSHVYLVQLVFPG------------KPPFEAVL 64
Query: 86 KRVIVPDENGLNELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKK 145
KR+ D L + EV TMK + V YY S R FE+L+L+E CP
Sbjct: 65 KRIFATDAMALRAVHEEVRTMKLVSNQKRCVSYYGSEFFRTSKNQ--FEVLVLLEYCPCG 122
Query: 146 SLLDYMNNKLATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKL 205
L+D++N +L +L+E EILKI DV+ A+A MHYL PLIHRD+KIENVL+ +++KL
Sbjct: 123 GLIDFLNTRLQVRLSEQEILKIASDVTEAVAVMHYLKPPLIHRDLKIENVLLAAPNSYKL 182
Query: 206 CDFGSTSMCFPIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIF 265
CDFGS P T + L +I TT QYR PEMI++++ I+EKSDIWALG+
Sbjct: 183 CDFGSACHPIPGAKTAAEAKQLEYDIEKFTTWQYRCPEMINVHKGFGIDEKSDIWALGVL 242
Query: 266 LYKLLFYTTPFELTGQFAILHSKYEIPQ-NGYSSKLINLIIIMLAENPSLRPNIYQVMHH 324
YKL +YTTPFE G AI++ Y P YS +L LI +L + P RPNIYQ
Sbjct: 243 FYKLCYYTTPFEHQGLAAIMNVSYAFPTFPPYSDRLKRLISTLLQQYPWQRPNIYQTFCE 302
Query: 325 VCSILKCDVPFTDKY 339
+C + + D Y
Sbjct: 303 ICKMRNVPIHIYDIY 317
>Hs9055206 [T] KOG1989 ARK protein kinase family
Length = 355
Score = 196 bits (498), Expect = 1e-49
Identities = 119/303 (39%), Positives = 166/303 (54%), Gaps = 23/303 (7%)
Query: 37 VGTHRCEILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIAC-LKRVIVPDENG 95
VG H+ + E LAEGGF+ ++ V+ G I C LKR+ V +
Sbjct: 46 VGRHQVTLEESLAEGGFSTVFLVR-----------------THGGIRCALKRMYVNNMPD 88
Query: 96 LNELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKL 155
LN + E+ MK+L G NIV Y D + D +E+L+LME C +++ MN KL
Sbjct: 89 LNVCKREITIMKELSGHKNIVGYLDCAVNSISDNV--WEVLILMEYCRAGQVVNQMNKKL 146
Query: 156 ATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCF 215
T TE E+L+I D A+A++H TP+IHRD+K+EN+L++ N+ LCDFGS + F
Sbjct: 147 QTGFTEPEVLQIFCDTCEAVARLHQCKTPIIHRDLKVENILLNDGGNYVLCDFGSATNKF 206
Query: 216 PIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTP 275
+ + V+ I +TT YR+PEMI+LY PI K+DIWALG LYKL F+T P
Sbjct: 207 -LNPQKDGVNVVEEEIKKYTTLSYRAPEMINLYGGKPITTKADIWALGCLLYKLCFFTLP 265
Query: 276 FELTGQFAILHSKYEIPQNG-YSSKLINLIIIMLAENPSLRPNIYQVMHHVCSILKCDVP 334
F Q AI + IP N YS + LI ML +P RP+I+QV + K D P
Sbjct: 266 FG-ESQVAICDGNFTIPDNSRYSRNIHCLIRFMLEPDPEHRPDIFQVSYFAFKFAKKDCP 324
Query: 335 FTD 337
++
Sbjct: 325 VSN 327
>Hs7662462 [T] KOG1989 ARK protein kinase family
Length = 863
Score = 186 bits (473), Expect = 1e-46
Identities = 111/299 (37%), Positives = 165/299 (55%), Gaps = 20/299 (6%)
Query: 37 VGTHRCEILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGL 96
+G + + E LAEGGFA ++ V+ G LKR+ V +E+ L
Sbjct: 41 IGRQQVTVDEVLAEGGFAIVFLVR----------------TSNGMKCALKRMFVNNEHDL 84
Query: 97 NELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLA 156
+ E++ M+ L G NIV Y DS+ + G +E+L+LM+ C +++ MN +L
Sbjct: 85 QVCKREIQIMRDLSGHKNIVGYIDSSINNVSSGDV-WEVLILMDFCRGGQVVNLMNQRLQ 143
Query: 157 TKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFP 216
T TE E+L+I D A+A++H TP+IHRD+K+EN+L+ ++ LCDFGS + F
Sbjct: 144 TGFTENEVLQIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDRGHYVLCDFGSATNKFQ 203
Query: 217 IVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTPF 276
T + + + + I +TT YR+PEM++LY I K+DIWALG LYKL ++T PF
Sbjct: 204 NPQT-EGVNAVEDEIKKYTTLSYRAPEMVNLYSGKIITTKADIWALGCLLYKLCYFTLPF 262
Query: 277 ELTGQFAILHSKYEIPQNG-YSSKLINLIIIMLAENPSLRPNIYQVMHHVCSILKCDVP 334
Q AI + IP N YS + LI ML +P RP+IYQV + +LK + P
Sbjct: 263 G-ESQVAICDGNFTIPDNSRYSQDMHCLIRYMLEPDPDKRPDIYQVSYFSFKLLKKECP 320
>7298508 [T] KOG1989 ARK protein kinase family
Length = 1460
Score = 176 bits (446), Expect = 1e-43
Identities = 111/286 (38%), Positives = 157/286 (54%), Gaps = 17/286 (5%)
Query: 37 VGTHRCEILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGL 96
VG + + LAEGGFA ++ + + G S K LKR+ V +E+ L
Sbjct: 41 VGRVTVTVEDVLAEGGFAMVFLARG-------NGGGSSSATKYA----LKRMYVNNEHDL 89
Query: 97 NELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLA 156
N + E++ L G NI+ Y DS+ + P G+ E+LLLM C K +L MN +L
Sbjct: 90 NVAKREIQIASNLSGHKNIIGYVDSSIT--PTGNGVCEVLLLMPYC-KHHMLAMMNARLH 146
Query: 157 TKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFP 216
TE E+L I D++ A++++HY TP+IHRD+K+EN+L NF LCDFGS +
Sbjct: 147 VGFTEPEVLNIFCDIAEAVSRLHYCQTPIIHRDLKVENILQTDAGNFVLCDFGSAT-AKT 205
Query: 217 IVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTPF 276
+ + V+ I +TT YR+PEMIDLY I K+DIWALG LYKL F++ PF
Sbjct: 206 LNPQQHGVTVVQEEIQKYTTLSYRAPEMIDLYGGKSITTKADIWALGCMLYKLCFFSLPF 265
Query: 277 ELTGQFAILHSKYEIPQNG-YSSKLINLIIIMLAENPSLRPNIYQV 321
AI + ++ IP + YS + LI ML + RPNI+QV
Sbjct: 266 G-ESTLAIQNGQFSIPDSSKYSKGMHQLIKYMLEPDMEKRPNIWQV 310
>At2g32850 [T] KOG1989 ARK protein kinase family
Length = 693
Score = 166 bits (420), Expect = 1e-40
Identities = 105/306 (34%), Positives = 159/306 (51%), Gaps = 23/306 (7%)
Query: 37 VGTHRCEILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGL 96
+G + ++ +AEGGF+++Y + + ++ A LK +I DE L
Sbjct: 22 IGNLKVQVRNVIAEGGFSSVYLAQDVNHASKQYA--------------LKHMICNDEESL 67
Query: 97 NELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLA 156
+ E+ +K L+G PN+V Y G E LL M+ C K SL+D + N+ A
Sbjct: 68 ELVMKEISVLKSLKGHPNVVTLYAHGILDM--GRNKKEALLAMDFCGK-SLVDVLENRGA 124
Query: 157 TKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFP 216
E + L I DV NA+ MH + HRD+K EN+L+ D +KLCDFGS S
Sbjct: 125 GYFEEKQALTIFRDVCNAVFAMHCQSPRIAHRDLKAENLLLSSDGQWKLCDFGSVSTNHK 184
Query: 217 IVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTPF 276
I +++ + +NI +TTP YR+PEM DL+R I+EK DIWALG L+++ ++ F
Sbjct: 185 IFERAEEMGIEEDNIRKYTTPTYRAPEMWDLFRREMISEKVDIWALGCLLFRICYFKNAF 244
Query: 277 ELTGQFAILHSKYEIPQN-GYSSKLINLIIIMLAENPSLRPNIYQVMHHVCSIL-----K 330
+ + IL+ Y IP++ YS + +LI ML +P RP+I QV I+ K
Sbjct: 245 DGESKLQILNGNYRIPESPKYSVFITDLIKEMLQASPDERPDITQVKSQFLLIVSSQLRK 304
Query: 331 CDVPFT 336
C + T
Sbjct: 305 CKMSLT 310
>Hs4885251_1 [T] KOG1989 ARK protein kinase family
Length = 395
Score = 162 bits (410), Expect = 2e-39
Identities = 113/301 (37%), Positives = 161/301 (52%), Gaps = 24/301 (7%)
Query: 35 VVVGTHRCEILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDEN 94
V +G R + LAEGGFA +Y+ + D G +G LKR++ +E
Sbjct: 33 VELGELRLRVRRVLAEGGFAFVYEAQ--------DVG-------SGREYALKRLLSNEEE 77
Query: 95 GLNELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPG-FEILLLMELCPKKSLLDYMNN 153
+ EV MK+L G PNIVQ+ + + + G E LLL ELC K L++++
Sbjct: 78 KNRAIIQEVCFMKKLSGHPNIVQFCSAASIGKEESDTGQAEFLLLTELC-KGQLVEFLK- 135
Query: 154 KLATK--LTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGST 211
K+ ++ L+ +LKI Y A+ MH P+IHRD+K+EN+L+ KLCDFGS
Sbjct: 136 KMESRGPLSCDTVLKIFYQTCRAVQHMHRQKPPIIHRDLKVENLLLSNQGTIKLCDFGSA 195
Query: 212 SMC--FPIVS-THQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYK 268
+ +P S + Q A++ I +TTP YR+PE+IDLY PI EK DIWALG LY
Sbjct: 196 TTISHYPDYSWSAQRRALVEEEITRNTTPMYRTPEIIDLYSNFPIGEKQDIWALGCILYL 255
Query: 269 LLFYTTPFELTGQFAILHSKYEIPQNGYSSKLI-NLIIIMLAENPSLRPNIYQVMHHVCS 327
L F PFE + I++ KY IP + + +LI ML NP R +I +V+H +
Sbjct: 256 LCFRQHPFEDGAKLRIVNGKYSIPPHDTQYTVFHSLIRAMLQVNPEERLSIAEVVHQLQE 315
Query: 328 I 328
I
Sbjct: 316 I 316
>7296894_1 [T] KOG1989 ARK protein kinase family
Length = 391
Score = 148 bits (373), Expect = 4e-35
Identities = 101/297 (34%), Positives = 146/297 (49%), Gaps = 20/297 (6%)
Query: 35 VVVGTHRCEILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDEN 94
V V HR I +AEGG+A +Y + ++ E LKR+I D
Sbjct: 43 VEVAGHRLRIKCVIAEGGYAFVYVAQDVQTGTEY---------------ALKRLIGADMQ 87
Query: 95 GLNELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNK 154
+ NE+ KQL G NIV + S+ + P G + LLL ELC SL+D
Sbjct: 88 ASTAIINEINIHKQLSGHENIVAFVGSSYTA-PSTQLGAQYLLLTELCKGGSLVDCFRTN 146
Query: 155 LATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGS--TS 212
A +L+I Y ++ A+A +H P+ HRDIKIEN L+ D KLCDFGS T
Sbjct: 147 NAP-FNPTCVLRIFYQMARAVASLHSQSPPIAHRDIKIENFLIGNDKQIKLCDFGSASTE 205
Query: 213 MCFPIVS-THQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLF 271
+ P + ++L + + TTP YRSPEM+D + PI K DIWALG LY L +
Sbjct: 206 VLSPTFEWSANQRSMLEDQLNTVTTPMYRSPEMLDTWSNNPIGPKVDIWALGCILYFLCY 265
Query: 272 YTTPFELTGQFAILHSKYEIPQNGYSSKLINLIIIMLAENPSLRPNIYQVMHHVCSI 328
P+E G+ I+++ Y +P + ++I L NP R +I V+ + ++
Sbjct: 266 RKHPYEDGGKLRIINANYMLPPDPQYQCFSDIIRGCLKVNPFERLDITMVLEGLAAL 322
>CE00972 [T] KOG1989 ARK protein kinase family
Length = 690
Score = 139 bits (349), Expect = 2e-32
Identities = 105/286 (36%), Positives = 148/286 (51%), Gaps = 27/286 (9%)
Query: 41 RCEILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPD-ENGLNEL 99
R I + +AEGGFA +Y D K K LKR D E L
Sbjct: 46 RVTIEKQIAEGGFAIVYVAS------------DRKNNKFA----LKRQFTKDNEKQLEAC 89
Query: 100 RNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATK- 158
E +KQ G NIV++ DS + +G +E +LL E +K++L MN +++
Sbjct: 90 CREHSFLKQCIGHKNIVEFVDSYTNCLGNGI--WECMLLTEY-HQKNVLQLMNERISQNQ 146
Query: 159 -LTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVD--KDDNFKLCDFGSTSMCF 215
LT EIL I D+ A++ +H P P+IHRD+K+ENVL+ K ++ LCDFGS +
Sbjct: 147 YLTNDEILSIFTDLCEAVSFIHNRPQPIIHRDLKVENVLISSHKPPHYVLCDFGSATTQI 206
Query: 216 PIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTP 275
V + + + + + +TT YRSPEMID Y L I KSDIWALG+ LY+L F+ P
Sbjct: 207 LSVEKY-GVEYVKSEVERNTTMCYRSPEMIDFYSGLEIGLKSDIWALGVLLYRLCFFCVP 265
Query: 276 FELTGQFAILHSKYEIPQNGYSSKLINLIIIMLAE-NPSLRPNIYQ 320
FE AI Y+ P I ++I ML + + + RP+IYQ
Sbjct: 266 FE-ESPLAIQSVNYQFPSVPNIPDEIKVLIYMLLDIDVNRRPSIYQ 310
>CE00971 [T] KOG1989 ARK protein kinase family
Length = 1077
Score = 139 bits (349), Expect = 2e-32
Identities = 105/286 (36%), Positives = 148/286 (51%), Gaps = 27/286 (9%)
Query: 41 RCEILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPD-ENGLNEL 99
R I + +AEGGFA +Y D K K LKR D E L
Sbjct: 46 RVTIEKQIAEGGFAIVYVAS------------DRKNNKFA----LKRQFTKDNEKQLEAC 89
Query: 100 RNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATK- 158
E +KQ G NIV++ DS + +G +E +LL E +K++L MN +++
Sbjct: 90 CREHSFLKQCIGHKNIVEFVDSYTNCLGNGI--WECMLLTEY-HQKNVLQLMNERISQNQ 146
Query: 159 -LTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVD--KDDNFKLCDFGSTSMCF 215
LT EIL I D+ A++ +H P P+IHRD+K+ENVL+ K ++ LCDFGS +
Sbjct: 147 YLTNDEILSIFTDLCEAVSFIHNRPQPIIHRDLKVENVLISSHKPPHYVLCDFGSATTQI 206
Query: 216 PIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTP 275
V + + + + + +TT YRSPEMID Y L I KSDIWALG+ LY+L F+ P
Sbjct: 207 LSVEKY-GVEYVKSEVERNTTMCYRSPEMIDFYSGLEIGLKSDIWALGVLLYRLCFFCVP 265
Query: 276 FELTGQFAILHSKYEIPQNGYSSKLINLIIIMLAE-NPSLRPNIYQ 320
FE AI Y+ P I ++I ML + + + RP+IYQ
Sbjct: 266 FE-ESPLAIQSVNYQFPSVPNIPDEIKVLIYMLLDIDVNRRPSIYQ 310
>CE04586 [T] KOG1989 ARK protein kinase family
Length = 570
Score = 109 bits (272), Expect = 2e-23
Identities = 86/277 (31%), Positives = 137/277 (49%), Gaps = 36/277 (12%)
Query: 48 LAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNELRNEVETMK 107
+A+GGF ++ TN + K++ + D A K ++ NE++ MK
Sbjct: 45 IAKGGFGTVFLA-----TNTKGKQVAVKIMLSHDAAATK-----------DIDNEIDMMK 88
Query: 108 QLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLTEAEI--- 164
+L+ NI+Q +D++A E + ME C K S+ D + K E I
Sbjct: 89 KLQHE-NIIQLFDASAESRSSNRSVKEYKISMEYC-KFSIADVL-----LKYKEVSIDFV 141
Query: 165 LKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGST---SMCFPIVSTH 221
++I+Y + A+ +H + IHRDIK EN+L++ + KLCDFGS S+ +S
Sbjct: 142 VRIIYFTTRALVYLHSVGA--IHRDIKAENLLINGNGKLKLCDFGSATTKSIEMAPLSNS 199
Query: 222 QDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTPFELTGQ 281
+ +AV ++ +TTP RSPE+ D+Y PI ++ D WA+G +Y + F PF+
Sbjct: 200 ERLAV-QEEMFKYTTPITRSPEVCDVYSNWPIGKQQDNWAMGCLIYFVAFGEHPFD-GSA 257
Query: 282 FAILHSKYEIP---QNGYSSKLINLIIIMLAENPSLR 315
AI++ KY+ P Q S +LI L NP R
Sbjct: 258 LAIINGKYKKPPPVQQNQLSAFADLIAKCLTPNPDER 294
>At5g08160 [KIT] KOG2345 Serine/threonine protein kinase/TGF-beta stimulated
factor
Length = 347
Score = 101 bits (251), Expect = 5e-21
Identities = 87/323 (26%), Positives = 144/323 (43%), Gaps = 29/323 (8%)
Query: 35 VVVGTHRCEILEHLAEGGFANIYKVKFLELTNEMDA---GIDSKL-----LKAGDIACLK 86
V + +R I+ L EGGFA ++ VK + A G+ K+ L A +K
Sbjct: 21 VWINENRFRIVRQLGEGGFAFVFLVKEIVADASSAASGGGLAKKVKDPAHLSADGTYAMK 80
Query: 87 RVIVPDENGLNELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPG---FEILLLMELCP 143
+V++ ++ L +R E+ + L PN++ D DG G E LL +
Sbjct: 81 KVLIQNKEQLELVREEIR-VSSLFNHPNLLPLLDHAIISVKDGQEGAWKHEAFLLFPVHL 139
Query: 144 KKSLLDYMNNKLATKLT--EAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDD 201
+LLD A K T ++L I + + + MH L P H D+K NVL+ +
Sbjct: 140 DGTLLDNFTLMKAKKETFSTTDVLHIFRQLCDGLKHMHSLEPPYAHNDVKPGNVLLTRRK 199
Query: 202 NFK----LCDFGSTSMCFPIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKS 257
L DFGS + + Q+ L H + +R+PE+ D I+E++
Sbjct: 200 GQPPLAILMDFGSARPSRKQIRSRQEALQLQEWTSEHCSAPFRAPELWDCPSHADIDERT 259
Query: 258 DIWALGIFLYKLLFYTTPFEL-------TGQFAILHSKYEIPQNG----YSSKLINLIII 306
DIW+LG LY +++ +PFE + Q AI++++ + P G Y L +
Sbjct: 260 DIWSLGCTLYAIMYGVSPFEYALGESGGSLQLAIVNAQIKWPNTGPKASYPEALHQFVTW 319
Query: 307 MLAENPSLRPNIYQVMHHVCSIL 329
ML ++RP I ++ HV ++
Sbjct: 320 MLQPQAAVRPRIDDIIIHVDKLI 342
>SPAC19E9.02 [D] KOG0591 NIMA (never in mitosis)-related G2-specific
serine/threonine protein kinase
Length = 722
Score = 93.2 bits (230), Expect = 1e-18
Identities = 93/303 (30%), Positives = 135/303 (43%), Gaps = 54/303 (17%)
Query: 43 EILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNELRNE 102
+ILE + G F IYKV+ L+ A + K + G+I ++ + DE +N LRN
Sbjct: 5 KILECIGHGSFGRIYKVQRLK----DGALLAQKEIHFGNITRQEKQYIADE--VNILRN- 57
Query: 103 VETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATK--LT 160
+K PNIVQY +R I L ME C L + + K T
Sbjct: 58 ---LKH----PNIVQYCGEELNRSAQ-----VINLYMEYCGHGDLANLIQRYKEEKKRFT 105
Query: 161 EAEILKIMYDVSNAIAQMHYLPTP-----------------LIHRDIKIENVLVDKDDNF 203
E E+LK + A+ + HY ++HRDIK N+ +D++++
Sbjct: 106 EQEVLKFFTQLLLALYRCHYGENAPACDSQWPREIFHPKQSVLHRDIKPANIFLDENNSV 165
Query: 204 KLCDFGSTSMCFPIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALG 263
KL DFG + + + V T + YV T P Y SPE+I R P + KSD+WALG
Sbjct: 166 KLGDFGLSKLL-------DNTRVFTQS-YVGT-PYYMSPEII---RSSPYSAKSDVWALG 213
Query: 264 IFLYKLLFYTTPFE----LTGQFAILHSKYEIPQNGYSSKLINLIIIMLAENPSLRPNIY 319
++++ T PFE L Q I + YS + LI L N LRP Y
Sbjct: 214 CVIFEICMLTHPFEGRSYLELQRNICQGNLSCWDHHYSDDVFLLIRHCLEVNSDLRPTTY 273
Query: 320 QVM 322
Q++
Sbjct: 274 QLL 276
>YPL236c [KIT] KOG2345 Serine/threonine protein kinase/TGF-beta stimulated
factor
Length = 364
Score = 91.7 bits (226), Expect = 4e-18
Identities = 88/341 (25%), Positives = 144/341 (41%), Gaps = 62/341 (18%)
Query: 37 VGTHRCEILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGL 96
V R I L EGG + +Y V+ + + +D GI + L A LK++I P +
Sbjct: 25 VNDKRYRIQRLLGEGGMSFVYLVQLSKNSLIIDNGIATPELYA-----LKKIICPSVESI 79
Query: 97 NELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKL- 155
+ E+E K+ + SP +++ DS + DGS I +++ SL D +N +L
Sbjct: 80 SNGMREIENYKRFQ-SPYVIKSIDSQVMQEKDGSK--TIYIVLPYYSLGSLQDSINRRLL 136
Query: 156 -ATKLTEAEILKIMYDVSNAIAQMH-----------------------------YLPTPL 185
T ++EAE ++IM V+ + +H TPL
Sbjct: 137 EGTFVSEAECVRIMLGVTRGLLCLHDPASRQDNATSRVNVDAVSMTYSDETAMLLEDTPL 196
Query: 186 ---------------IHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTHQDIAVLTNN 230
HRDI N+L D + D GS S + ++ L
Sbjct: 197 EMDMLSSNSAGSIAYAHRDITPSNILFSSDGLPVIGDLGSCSQADITIENRHQLSELQEW 256
Query: 231 IYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTPFELTGQ-------FA 283
+ + T Y PE+++L ++ K DIW+LG Y L+F +PFE Q +A
Sbjct: 257 VNDNCTLPYTPPELLNLKLNQVLSSKVDIWSLGCTFYTLMFGISPFEREEQIHGASLTYA 316
Query: 284 ILHSKYEIPQNG-YSSKLINLIIIMLAENPSLRPNIYQVMH 323
I KY P+N +S L+++I + +P RP Q+++
Sbjct: 317 INTGKYSFPRNSRFSEGLLSVIKKCIQVDPIQRPTTSQLLN 357
>SPAC23C11.16 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 683
Score = 89.7 bits (221), Expect = 2e-17
Identities = 81/288 (28%), Positives = 132/288 (45%), Gaps = 52/288 (18%)
Query: 48 LAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNELRNEVETMK 107
+ EGGFA ++VK + A IA KR + D+ L +L E++ +
Sbjct: 47 IGEGGFARCFRVK----------DNYGNIYAAKVIA--KRSLQNDKTKL-KLFGEIK-VH 92
Query: 108 QLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLTEAEILKI 167
Q PNIV + D I L++ELC KSL++ + + +LTE E+ +
Sbjct: 93 QSMSHPNIVGFIDCFED-------STNIYLILELCEHKSLMELLRKR--KQLTEPEVRYL 143
Query: 168 MYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTHQDIAVL 227
M + A+ MH +IHRD+K+ N+++D+ +N K+ DFG ++ I
Sbjct: 144 MMQILGALKYMH--KKRVIHRDLKLGNIMLDESNNVKIGDFGLAALLMDDEERKMTIC-- 199
Query: 228 TNNIYVHTTPQYRSPEMIDLYRCLPINEKS------DIWALGIFLYKLLFYTTPFE---- 277
TP Y +PE++ N K D+W+ G+ +Y LL PF+
Sbjct: 200 -------GTPNYIAPEIL-------FNSKEGHSFEVDLWSAGVVMYALLIGKPPFQDKEV 245
Query: 278 LTGQFAILHSKYEIPQN-GYSSKLINLIIIMLAENPSLRPNIYQVMHH 324
T I + Y P N S++ +LI +L +PS+RP+I ++ H
Sbjct: 246 KTIYRKIKANSYSFPSNVDISAEAKDLISSLLTHDPSIRPSIDDIVDH 293
>CE26793_1 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 795
Score = 88.6 bits (218), Expect = 4e-17
Identities = 88/323 (27%), Positives = 146/323 (44%), Gaps = 53/323 (16%)
Query: 13 VAHTAATSAMIPNSHLLS---PNTQVVVGTHRCEILEHLAEGGFANIYKVKFLELTNEMD 69
V H S I +H +S P + HR EI + L G + + L ++ D
Sbjct: 43 VTHEPTCSKYIYGTHPMSGAEPCSPTKKEKHRFEITKKLGSGTYGKVS----LAYDHKFD 98
Query: 70 AGIDSKLLKAGDIACLKRVIVPDENGLNELRNEVETMKQLRGSPNIVQYYDSNASRHPDG 129
+ KL+K + + + L +R E+ M L PNI+Q Y+ ++
Sbjct: 99 REVAVKLIK--------KSAIESKADLVRIRREIRIMSALN-HPNIIQIYEVFENKD--- 146
Query: 130 SPGFEILLLMELCPKKSLLDYMNNKLATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRD 189
+I+L+ME L DY++ L EAE +I +++A+ H + HRD
Sbjct: 147 ----KIILVMEYSSGGELYDYVSR--CGSLPEAEARRIFRQITSAVLYCH--KHRVAHRD 198
Query: 190 IKIENVLVDKDDNFKLCDFGSTSMCFPIVSTHQDIAVLTNNIYVHTTPQYRSPEMID--L 247
+K+EN+L+D+++N K+ DFG + + D +LT +P Y SPE+I+
Sbjct: 199 LKLENILLDQNNNAKIADFG-------LSNYFADKNLLTT---FCGSPLYASPEIINGTP 248
Query: 248 YRCLPINEKSDIWALGIFLYKLLFYTTPFE------LTGQFAILHSKYEIPQNGYSSKLI 301
Y+ + D W+LGI LY L++ + PF+ + Q I Y P+ ++ +
Sbjct: 249 YK----GPEVDCWSLGILLYTLVYGSMPFDGRDFNRMVRQ--IKRGAYFEPETPSTASM- 301
Query: 302 NLIIIMLAENPSLRPNIYQVMHH 324
LI ML NP R I+ + H
Sbjct: 302 -LIRNMLRVNPERRATIFDIASH 323
>Hs7662170 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 661
Score = 86.7 bits (213), Expect = 1e-16
Identities = 75/292 (25%), Positives = 134/292 (45%), Gaps = 48/292 (16%)
Query: 40 HRCEILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNEL 99
HR E+ E L +G + + + E +G + I +++ + DE + +
Sbjct: 53 HRYELQETLGKGTYGKVKRA------TERFSG------RVVAIKSIRKDKIKDEQDMVHI 100
Query: 100 RNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKL 159
R E+E M L P+I+ Y+ ++ +I+++ME K L DY++ + +L
Sbjct: 101 RREIEIMSSLN-HPHIISIYEVFENKD-------KIVIIMEYASKGELYDYISER--RRL 150
Query: 160 TEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVS 219
+E E + +A+ H ++HRD+K+EN+L+D + N K+ DFG +++
Sbjct: 151 SERETRHFFRQIVSAVHYCH--KNGVVHRDLKLENILLDDNCNIKIADFGLSNL------ 202
Query: 220 THQDIAVLTNNIYVHT---TPQYRSPEMID--LYRCLPINEKSDIWALGIFLYKLLFYTT 274
+ ++ T +P Y SPE+++ YR + D WALG+ LY L++ T
Sbjct: 203 -------YQKDKFLQTFCGSPLYASPEIVNGRPYR----GPEVDSWALGVLLYTLVYGTM 251
Query: 275 PFELTGQFAILH--SKYEIPQNGYSSKLINLIIIMLAENPSLRPNIYQVMHH 324
PF+ ++ S E + S LI ML NP R I + +H
Sbjct: 252 PFDGFDHKNLIRQISSGEYREPTQPSDARGLIRWMLMVNPDRRATIEDIANH 303
>At1g66880 [T] KOG1187 Serine/threonine protein kinase
Length = 1286
Score = 85.9 bits (211), Expect = 2e-16
Identities = 81/290 (27%), Positives = 134/290 (45%), Gaps = 48/290 (16%)
Query: 2 SKSDTISRPNSVAHTAATS-AMIPN-SHLLSPNTQVVVGTHRCEILEH--------LAEG 51
S DT P S +++++ +++P+ S+L + + V E LE L +G
Sbjct: 907 SSRDTSRNPTSTTISSSSNHSLLPSISNLANRSDYCGVQVFSYEELEEATENFSRELGDG 966
Query: 52 GFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNELRNEVETMKQLRG 111
GF +Y +LK G +KR+ + + +NE+E +K L+
Sbjct: 967 GFGTVYY----------------GVLKDGRAVAVKRLYERSLKRVEQFKNEIEILKSLK- 1009
Query: 112 SPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYM--NNKLATKLTEAEILKIMY 169
PN+V Y SRH E+LL+ E +L +++ N A L + L I
Sbjct: 1010 HPNLVILYGCT-SRHSR-----ELLLVYEYISNGTLAEHLHGNRAEARPLCWSTRLNIAI 1063
Query: 170 DVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTHQDIAVLTN 229
+ ++A++ +H +IHRDIK N+L+D + K+ DFG S FP+ TH A
Sbjct: 1064 ETASALSFLHI--KGIIHRDIKTTNILLDDNYQVKVADFG-LSRLFPMDQTHISTA---- 1116
Query: 230 NIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTPFELT 279
TP Y PE Y+C +NEKSD+++ G+ L +L+ ++T
Sbjct: 1117 ---PQGTPGYVDPE---YYQCYQLNEKSDVYSFGVVLTELISSKEAVDIT 1160
>SPAC890.03 [T] KOG0583 Serine/threonine protein kinase
Length = 672
Score = 85.5 bits (210), Expect = 3e-16
Identities = 88/293 (30%), Positives = 137/293 (46%), Gaps = 49/293 (16%)
Query: 37 VGTHRCEILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGL 96
VGT+R E + + EG F +Y L LTN +LK+ +C K+ I+
Sbjct: 28 VGTYRIESV--VGEGSFGKVYLAAHL-LTNT------KVVLKS---SCRKQAII------ 69
Query: 97 NELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLA 156
L E+ ++L PNI + Y+ + I L ME CP L D++ +
Sbjct: 70 --LAREIHHHRRLL-HPNITRLYEVVCTED-------RIYLAMEYCPNGELYDWVARE-- 117
Query: 157 TKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFP 216
+L E +IM+ + AI +H +HRD+K+EN+ +DK N KL DFG
Sbjct: 118 KRLDEKTTCRIMWQLCCAIQYLHR--QGCVHRDLKLENIFLDKAYNVKLGDFG------- 168
Query: 217 IVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTPF 276
S D + T T Y +PE++ ++ I E DIW+LGI +Y LL PF
Sbjct: 169 -FSRDSDCSRRTFMNTRCGTVAYCAPELVQGHKY--IGECVDIWSLGIIMYALLIGRLPF 225
Query: 277 E-----LTGQFAILHSKYEIPQNGYSSKLINLIIIMLAENPSLRPNIYQVMHH 324
+ LT Q I++ + P+ S +L+ +L ++ LRP+I Q++ H
Sbjct: 226 DEDDVSLTEQ-KIINECPQYPET-LSKNSSSLLKSLLCKDYRLRPSIDQIISH 276
>YPL150w [T] KOG0583 Serine/threonine protein kinase
Length = 901
Score = 85.1 bits (209), Expect = 4e-16
Identities = 82/289 (28%), Positives = 132/289 (45%), Gaps = 53/289 (18%)
Query: 43 EILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNELRNE 102
+IL+ + EG F +Y ++ CLK D+N N +R E
Sbjct: 42 KILKQIGEGSFGKVYLALHRPTHRKV---------------CLK---TSDKNDPNIVR-E 82
Query: 103 VETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLTEA 162
V +Q P I + Y+ + ++ + +E CP K L D++ + L E
Sbjct: 83 VFYHRQF-DFPYITKLYEVIVTES-------KVWMALEYCPGKELYDHLLSLRRISLLEC 134
Query: 163 EILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTHQ 222
++ +S A+ H + +HRD+K+EN+L+DK+ N KL DFG T C
Sbjct: 135 G--ELFAQISGAVYYAHSMHC--VHRDLKLENILLDKNGNAKLTDFGFTRECM------- 183
Query: 223 DIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTPFELTGQF 282
T V T Y +PE+I+ R K DIW+LG+ LY L+ PF+ +
Sbjct: 184 ---TKTTLETVCGTTVYMAPELIE--RRTYDGFKIDIWSLGVILYTLITGYLPFDDDDE- 237
Query: 283 AILHSKYEI--PQNGYSSKLI-----NLIIIMLAENPSLRPNIYQVMHH 324
+K++I + Y +K+I +LI +LA+NP RP++ QV+ H
Sbjct: 238 --AKTKWKIVNEEPKYDAKVIPDDARDLISRLLAKNPGERPSLSQVLRH 284
>At4g23050 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 736
Score = 84.7 bits (208), Expect = 5e-16
Identities = 60/241 (24%), Positives = 122/241 (49%), Gaps = 28/241 (11%)
Query: 96 LNELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKL 155
L E + E+ MK+LR PN++ + + + ++ME P+ SL ++N
Sbjct: 507 LTECKKEINIMKKLR-HPNVLLFMGAVCTEEKSA-------IIMEYMPRGSLFKILHNT- 557
Query: 156 ATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCF 215
L + L++ DV+ + +H P++HRD+K N+LVDK+ N K+ DFG
Sbjct: 558 NQPLDKKRRLRMALDVARGMNYLHRRNPPIVHRDLKSSNLLVDKNWNVKVGDFG------ 611
Query: 216 PIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTP 275
+S ++ L+ TPQ+ +PE++ R P NEK D+++ G+ L++L+ P
Sbjct: 612 --LSKWKNATFLSTK-SGKGTPQWMAPEVL---RSEPSNEKCDVFSFGVILWELMTTLVP 665
Query: 276 F------ELTGQFAILHSKYEIPQNGYSSKLINLIIIMLAENPSLRPNIYQVMHHVCSIL 329
+ ++ G + + ++P+ G + ++ ++I +P+ RP+ +++ + S+
Sbjct: 666 WDRLNSIQVVGVVGFMDRRLDLPE-GLNPRIASIIQDCWQTDPAKRPSFEELISQMMSLF 724
Query: 330 K 330
+
Sbjct: 725 R 725
>YDL159w [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K)
Length = 515
Score = 84.3 bits (207), Expect = 7e-16
Identities = 87/358 (24%), Positives = 160/358 (44%), Gaps = 57/358 (15%)
Query: 1 MSKSDTISRPNSVAHTAATSAMIPNSHLLS-PNTQVVVGTHRCEILEHLAEGGFANIYKV 59
+S S T S P+++ + + + N H +S P + + ++ + L+ N ++
Sbjct: 129 LSPSSTNSTPSTIQGLSNIATPVENEHSISLPPLEESLSPAAADLKDTLSGTSNGNYIQL 188
Query: 60 KFLELTNEMDAGIDSKLLKA-----GDIACLKRVIVPDENG--LNELRNEVETMKQLRGS 112
+ L ++ AG ++KA I K + V N +N+L E+ +K ++
Sbjct: 189 QDLVQLGKIGAGNSGTVVKALHVPDSKIVAKKTIPVEQNNSTIINQLVRELSIVKNVKPH 248
Query: 113 PNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMN-----------NKLATKLTE 161
NI+ +Y + ++H + EI++LME SL ++ + T E
Sbjct: 249 ENIITFYGAYYNQHINN----EIIILMEYSDCGSLDKILSVYKRFVQRGTVSSKKTWFNE 304
Query: 162 AEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTH 221
I KI Y V N + + Y +IHRDIK NVL++ KLCDFG + ++++
Sbjct: 305 LTISKIAYGVLNGLDHL-YRQYKIIHRDIKPSNVLINSKGQIKLCDFGVSK---KLINSI 360
Query: 222 QDIAVLTNNIYVHTTPQYRSPEMI--DLYRCLPINEKSDIWALGIFLYKLLFYTTPFELT 279
D V T+ Y SPE I ++Y + K D+W+LG+ + +L+ T F L
Sbjct: 361 ADTFVGTST--------YMSPERIQGNVY-----SIKGDVWSLGLMIIELV--TGEFPLG 405
Query: 280 G------------QFAILHSKYEIPQNG-YSSKLINLIIIMLAENPSLRPNIYQVMHH 324
G Q + +P++ YS ++ + + +N R +I++++HH
Sbjct: 406 GHNDTPDGILDLLQRIVNEPSPRLPKDRIYSKEMTDFVNRCCIKNERERSSIHELLHH 463
>Hs7657214 [T] KOG0583 Serine/threonine protein kinase
Length = 714
Score = 84.0 bits (206), Expect = 9e-16
Identities = 67/230 (29%), Positives = 112/230 (48%), Gaps = 28/230 (12%)
Query: 99 LRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATK 158
LR E + + +R PNI Q D + + L+MELCP +L+ + K +
Sbjct: 108 LRREGQIQQMIR-HPNITQLLDILETEN-------SYYLVMELCPGGNLMHKIYEK--KR 157
Query: 159 LTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIV 218
L E+E + + + +A+ +H ++HRD+KIEN+L+D+D+N KL DFG S C I+
Sbjct: 158 LEESEARRYIRQLISAVEHLHR--AGVVHRDLKIENLLLDEDNNIKLIDFG-LSNCAGIL 214
Query: 219 STHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLL-----FYT 273
+ +P Y +PE++ + P K D+W++G+ +Y +L F
Sbjct: 215 GYSDPFSTQCG------SPAYAAPELLARKKYGP---KIDVWSIGVNMYAMLTGTLPFTV 265
Query: 274 TPFELTGQFAILHSKYEIP-QNGYSSKLINLIIIMLAENPSLRPNIYQVM 322
PF L + + K P S+ I+ + +L +P RPNI Q +
Sbjct: 266 EPFSLRALYQKMVDKEMNPLPTQLSTGAISFLRSLLEPDPVKRPNIQQAL 315
>7298833 [KIT] KOG2345 Serine/threonine protein kinase/TGF-beta stimulated
factor
Length = 320
Score = 83.2 bits (204), Expect = 1e-15
Identities = 70/302 (23%), Positives = 135/302 (44%), Gaps = 28/302 (9%)
Query: 41 RCEILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNELR 100
R I E LA GGF+ I D G ++ ++ +KR+ + N
Sbjct: 29 RYTIRERLATGGFSLI------------DLGENASTRRS---YAIKRITCHSIDDQNIAL 73
Query: 101 NEVETMKQLRGSPNIVQYYDSNASRHPDG--SPGFEILLLMELCPKKSLLDYMN--NKLA 156
E+E +++ S N+++ D D + + +++ SL D++ ++
Sbjct: 74 REIENCRKI-DSENVIRVVDYELKGQADIVINTTSTLFIVLPYYKHGSLADHLQLRSRKQ 132
Query: 157 TKLTEAEILKIMYDVSNAIAQMHY-LPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCF 215
+ EA+IL+I V + +H +P PL HRD+K N+ + + D GS +
Sbjct: 133 DHMPEAQILQIFLGVCEGLKAIHEAMPVPLAHRDLKTANICLSDSFEPIIVDLGSMTEAR 192
Query: 216 PIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTP 275
+ D L + ++ YR+PE+ + I+E++DIW+LG LY + ++ +P
Sbjct: 193 LQIVGQTDAQRLQDEAEERSSIVYRAPELFTVKTYCTIDERTDIWSLGCVLYAMCYFNSP 252
Query: 276 FELTGQ------FAILHSKYEIPQNG-YSSKLINLIIIMLAENPSLRPNIYQVMHHVCSI 328
++ + A+L IP++ Y+ + LI ML +P RP ++ V+ +
Sbjct: 253 YDPIYERGDSVALAVLSGNINIPEDSIYTEDMHELIKYMLRTDPMERPFVFSVIERTHDL 312
Query: 329 LK 330
++
Sbjct: 313 IQ 314
>7292679 [G] KOG0599 Phosphorylase kinase gamma subunit
Length = 560
Score = 83.2 bits (204), Expect = 1e-15
Identities = 68/239 (28%), Positives = 111/239 (45%), Gaps = 31/239 (12%)
Query: 96 LNELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKL 155
L R E+ ++Q+ G P I+ D S + L+ ELCPK L DY+ + +
Sbjct: 71 LEATRQEISILRQVMGHPYIIDLQDVFES-------DAFVFLVFELCPKGELFDYLTSVV 123
Query: 156 ATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCF 215
L+E + IM + + +H ++HRD+K EN+L+D++ N K+ DFG
Sbjct: 124 T--LSEKKTRTIMRQIFEGVEYIH--AKSIVHRDLKPENILLDENHNVKITDFGFAKQL- 178
Query: 216 PIVSTHQDIAVLTNNIYVHTTPQYRSPEMI--DLYRCLP-INEKSDIWALGIFLYKLLFY 272
Q+ LTN + TP Y +PE + +++ P +++ DIWA G+ ++ LL
Sbjct: 179 ------QEGEKLTN---LCGTPGYLAPETLKCNMFEGSPGYSQEVDIWACGVIMFTLLVG 229
Query: 273 TTPFELTGQFA----ILHSKYEIPQNGY---SSKLINLIIIMLAENPSLRPNIYQVMHH 324
PF Q I+ KY + S +LI L +PS R + +V+ H
Sbjct: 230 CPPFWHRKQMVMLRNIMEGKYSFTSPEWADISEDPKDLIRKCLVVDPSQRITVKEVLRH 288
>YMR001c [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 705
Score = 82.8 bits (203), Expect = 2e-15
Identities = 80/287 (27%), Positives = 134/287 (45%), Gaps = 48/287 (16%)
Query: 48 LAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNELRNEVETMK 107
L EGGFA +++K D+G ++ A +A + + E +L +E++ K
Sbjct: 88 LGEGGFARCFQIKD-------DSG---EIFAAKTVA---KASIKSEKTRKKLLSEIQIHK 134
Query: 108 QLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLTEAEILKI 167
+ PNIVQ+ D D S + +L+E+CP SL++ + + LTE E+
Sbjct: 135 SM-SHPNIVQFIDC----FEDDS---NVYILLEICPNGSLMELLKRRKV--LTEPEVRFF 184
Query: 168 MYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTHQDIAVL 227
+ AI MH +IHRD+K+ N+ D + N K+ DFG AVL
Sbjct: 185 TTQICGAIKYMH--SRRVIHRDLKLGNIFFDSNYNLKIGDFGLA-------------AVL 229
Query: 228 TN----NIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTPFELTGQFA 283
N + TP Y +PE++ + + + + DIW+LG+ LY LL PF+
Sbjct: 230 ANESERKYTICGTPNYIAPEVL-MGKHSGHSFEVDIWSLGVMLYALLIGKPPFQARDVNT 288
Query: 284 ILH----SKYEIPQN-GYSSKLINLIIIMLAENPSLRPNIYQVMHHV 325
I + P++ S + LI +L+ +P RP++ ++M +V
Sbjct: 289 IYERIKCRDFSFPRDKPISDEGKILIRDILSLDPIERPSLTEIMDYV 335
>At5g03730 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 821
Score = 82.8 bits (203), Expect = 2e-15
Identities = 69/253 (27%), Positives = 123/253 (48%), Gaps = 28/253 (11%)
Query: 96 LNELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKL 155
+NE EV MK+LR PNIV + + ++ P+ S ++ E + SL ++
Sbjct: 590 VNEFLREVAIMKRLR-HPNIVLFMGA-VTQPPNLS------IVTEYLSRGSLYRLLHKSG 641
Query: 156 ATK-LTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMC 214
A + L E L + YDV+ + +H P++HRD+K N+LVDK K+CDFG + +
Sbjct: 642 AREQLDERRRLSMAYDVAKGMNYLHNRNPPIVHRDLKSPNLLVDKKYTVKVCDFGLSRLK 701
Query: 215 FPIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTT 274
+ + A TP++ +PE++ R P NEKSD+++ G+ L++L
Sbjct: 702 ASTFLSSKSAA---------GTPEWMAPEVL---RDEPSNEKSDVYSFGVILWELATLQQ 749
Query: 275 PF------ELTGQFAILHSKYEIPQNGYSSKLINLIIIMLAENPSLRPNIYQVMHHVCSI 328
P+ ++ + EIP+N + ++ +I P RP+ +M + +
Sbjct: 750 PWGNLNPAQVVAAVGFKCKRLEIPRN-LNPQVAAIIEGCWTNEPWKRPSFATIMDLLRPL 808
Query: 329 LKCDVPFTDKYEL 341
+K VP ++ +L
Sbjct: 809 IKSAVPPPNRSDL 821
>HsM4758524 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1165
Score = 82.4 bits (202), Expect = 3e-15
Identities = 75/292 (25%), Positives = 129/292 (43%), Gaps = 41/292 (14%)
Query: 43 EILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNELRNE 102
E++E + G + +YK + +K G +A +K + V ++ E++ E
Sbjct: 26 ELVEVVGNGTYGQVYK---------------GRHVKTGQLAAIKVMDVTEDEE-EEIKLE 69
Query: 103 VETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLTEA 162
+ +K+ NI YY + + P G ++ L+ME C S+ D + N L E
Sbjct: 70 INMLKKYSHHRNIATYYGAFIKKSPPGHDD-QLWLVMEFCGAGSITDLVKNTKGNTLKED 128
Query: 163 EILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTHQ 222
I I ++ +A +H +IHRDIK +NVL+ ++ KL DFG VS
Sbjct: 129 WIAYISREILRGLAHLHI--HHVIHRDIKGQNVLLTENAEVKLVDFG--------VSAQL 178
Query: 223 DIAVLTNNIYVHTTPQYRSPEMI--DLYRCLPINEKSDIWALGIFLYKLLFYTTPFELTG 280
D V N ++ TP + +PE+I D + +SD+W+ GI ++ P
Sbjct: 179 DRTVGRRNTFI-GTPYWMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGAPPL---C 234
Query: 281 QFAILHSKYEIPQN--------GYSSKLINLIIIMLAENPSLRPNIYQVMHH 324
+ + + IP+N +S K + I L +N RP+ Q++ H
Sbjct: 235 DMHPMRALFLIPRNPPPRLKSKKWSKKFFSFIEGCLVKNYMQRPSTEQLLKH 286
>Hs7657335 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1295
Score = 82.4 bits (202), Expect = 3e-15
Identities = 76/290 (26%), Positives = 129/290 (44%), Gaps = 41/290 (14%)
Query: 43 EILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNELRNE 102
E++E + G + +YK + +K G +A +K + V ++ E++ E
Sbjct: 26 ELVEVVGNGTYGQVYK---------------GRHVKTGQLAAIKVMDVTEDEE-EEIKQE 69
Query: 103 VETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLTEA 162
+ +K+ NI YY + + P G+ ++ L+ME C S+ D + N L E
Sbjct: 70 INMLKKYSHHRNIATYYGAFIKKSPPGNDD-QLWLVMEFCGAGSVTDLVKNTKGNALKED 128
Query: 163 EILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTHQ 222
I I ++ +A +H +IHRDIK +NVL+ ++ KL DFG VS
Sbjct: 129 CIAYICREILRGLAHLH--AHKVIHRDIKGQNVLLTENAEVKLVDFG--------VSAQL 178
Query: 223 DIAVLTNNIYVHTTPQYRSPEMI--DLYRCLPINEKSDIWALGIFLYKLLFYTTPFELTG 280
D V N ++ TP + +PE+I D + +SDIW+LGI ++ P
Sbjct: 179 DRTVGRRNTFI-GTPYWMAPEVIACDENPDATYDYRSDIWSLGITAIEMAEGAPPL---C 234
Query: 281 QFAILHSKYEIPQN--------GYSSKLINLIIIMLAENPSLRPNIYQVM 322
+ + + IP+N +S K I+ I L + RP Q++
Sbjct: 235 DMHPMRALFLIPRNPPPRLKSKKWSKKFIDFIDTCLIKTYLSRPPTEQLL 284
>Hs5730055 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 685
Score = 82.4 bits (202), Expect = 3e-15
Identities = 74/283 (26%), Positives = 130/283 (45%), Gaps = 45/283 (15%)
Query: 48 LAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNELRNEVETMK 107
L +GGFA Y++ +LTN + A I RV P + ++ E+E +
Sbjct: 88 LGKGGFAKCYEMT--DLTNNK--------VYAAKIIPHSRVAKPHQR--EKIDKEIELHR 135
Query: 108 QLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLTEAEILKI 167
L ++VQ+Y + I +L+E C ++S+ + K LTE E+
Sbjct: 136 ILHHK-HVVQFYHYFEDKE-------NIYILLEYCSRRSMAHIL--KARKVLTEPEVRYY 185
Query: 168 MYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTHQDIAVL 227
+ + + + +H ++HRD+K+ N +++ K+ DFG + P+ + I
Sbjct: 186 LRQIVSGLKYLH--EQEILHRDLKLGNFFINEAMELKVGDFGLAARLEPLEHRRRTIC-- 241
Query: 228 TNNIYVHTTPQYRSPEMIDL--YRCLPINEKSDIWALGIFLYKLLFYTTPFELTG----Q 281
TP Y SPE+++ + C +SDIWALG +Y +L PFE T
Sbjct: 242 -------GTPNYLSPEVLNKQGHGC-----ESDIWALGCVMYTMLLGRPPFETTNLKETY 289
Query: 282 FAILHSKYEIPQNGYSSKLINLIIIMLAENPSLRPNIYQVMHH 324
I ++Y +P + + +LI ML++NP RP++ ++ H
Sbjct: 290 RCIREARYTMP-SSLLAPAKHLIASMLSKNPEDRPSLDDIIRH 331
>Hs22035606 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1212
Score = 82.4 bits (202), Expect = 3e-15
Identities = 75/292 (25%), Positives = 129/292 (43%), Gaps = 41/292 (14%)
Query: 43 EILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNELRNE 102
E++E + G + +YK + +K G +A +K + V ++ E++ E
Sbjct: 26 ELVEVVGNGTYGQVYK---------------GRHVKTGQLAAIKVMDVTEDEE-EEIKLE 69
Query: 103 VETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLTEA 162
+ +K+ NI YY + + P G ++ L+ME C S+ D + N L E
Sbjct: 70 INMLKKYSHHRNIATYYGAFIKKSPPGHDD-QLWLVMEFCGAGSITDLVKNTKGNTLKED 128
Query: 163 EILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTHQ 222
I I ++ +A +H +IHRDIK +NVL+ ++ KL DFG VS
Sbjct: 129 WIAYISREILRGLAHLHI--HHVIHRDIKGQNVLLTENAEVKLVDFG--------VSAQL 178
Query: 223 DIAVLTNNIYVHTTPQYRSPEMI--DLYRCLPINEKSDIWALGIFLYKLLFYTTPFELTG 280
D V N ++ TP + +PE+I D + +SD+W+ GI ++ P
Sbjct: 179 DRTVGRRNTFI-GTPYWMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGAPPL---C 234
Query: 281 QFAILHSKYEIPQN--------GYSSKLINLIIIMLAENPSLRPNIYQVMHH 324
+ + + IP+N +S K + I L +N RP+ Q++ H
Sbjct: 235 DMHPMRALFLIPRNPPPRLKSKKWSKKFFSFIEGCLVKNYMQRPSTEQLLKH 286
>Hs22035604 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1320
Score = 82.4 bits (202), Expect = 3e-15
Identities = 75/292 (25%), Positives = 129/292 (43%), Gaps = 41/292 (14%)
Query: 43 EILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNELRNE 102
E++E + G + +YK + +K G +A +K + V ++ E++ E
Sbjct: 26 ELVEVVGNGTYGQVYK---------------GRHVKTGQLAAIKVMDVTEDEE-EEIKLE 69
Query: 103 VETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLTEA 162
+ +K+ NI YY + + P G ++ L+ME C S+ D + N L E
Sbjct: 70 INMLKKYSHHRNIATYYGAFIKKSPPGHDD-QLWLVMEFCGAGSITDLVKNTKGNTLKED 128
Query: 163 EILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTHQ 222
I I ++ +A +H +IHRDIK +NVL+ ++ KL DFG VS
Sbjct: 129 WIAYISREILRGLAHLHI--HHVIHRDIKGQNVLLTENAEVKLVDFG--------VSAQL 178
Query: 223 DIAVLTNNIYVHTTPQYRSPEMI--DLYRCLPINEKSDIWALGIFLYKLLFYTTPFELTG 280
D V N ++ TP + +PE+I D + +SD+W+ GI ++ P
Sbjct: 179 DRTVGRRNTFI-GTPYWMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGAPPL---C 234
Query: 281 QFAILHSKYEIPQN--------GYSSKLINLIIIMLAENPSLRPNIYQVMHH 324
+ + + IP+N +S K + I L +N RP+ Q++ H
Sbjct: 235 DMHPMRALFLIPRNPPPRLKSKKWSKKFFSFIEGCLVKNYMQRPSTEQLLKH 286
>Hs22035602 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1166
Score = 82.4 bits (202), Expect = 3e-15
Identities = 75/292 (25%), Positives = 129/292 (43%), Gaps = 41/292 (14%)
Query: 43 EILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNELRNE 102
E++E + G + +YK + +K G +A +K + V ++ E++ E
Sbjct: 26 ELVEVVGNGTYGQVYK---------------GRHVKTGQLAAIKVMDVTEDEE-EEIKLE 69
Query: 103 VETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLTEA 162
+ +K+ NI YY + + P G ++ L+ME C S+ D + N L E
Sbjct: 70 INMLKKYSHHRNIATYYGAFIKKSPPGHDD-QLWLVMEFCGAGSITDLVKNTKGNTLKED 128
Query: 163 EILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTHQ 222
I I ++ +A +H +IHRDIK +NVL+ ++ KL DFG VS
Sbjct: 129 WIAYISREILRGLAHLHI--HHVIHRDIKGQNVLLTENAEVKLVDFG--------VSAQL 178
Query: 223 DIAVLTNNIYVHTTPQYRSPEMI--DLYRCLPINEKSDIWALGIFLYKLLFYTTPFELTG 280
D V N ++ TP + +PE+I D + +SD+W+ GI ++ P
Sbjct: 179 DRTVGRRNTFI-GTPYWMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGAPPL---C 234
Query: 281 QFAILHSKYEIPQN--------GYSSKLINLIIIMLAENPSLRPNIYQVMHH 324
+ + + IP+N +S K + I L +N RP+ Q++ H
Sbjct: 235 DMHPMRALFLIPRNPPPRLKSKKWSKKFFSFIEGCLVKNYMQRPSTEQLLKH 286
>Hs13569922 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 628
Score = 82.4 bits (202), Expect = 3e-15
Identities = 79/293 (26%), Positives = 134/293 (44%), Gaps = 51/293 (17%)
Query: 40 HRCEILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNEL 99
HR E LE L +G + + K + E + + A I +++ + DE L +
Sbjct: 51 HRYEFLETLGKGTYGKVKKAR--ESSGRLVA-----------IKSIRKDKIKDEQDLMHI 97
Query: 100 RNEVETMKQLRGSPNIVQYYD--SNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLAT 157
R E+E M L P+I+ ++ N+S+ I+++ME + L DY++ +
Sbjct: 98 RREIEIMSSLN-HPHIIAIHEVFENSSK---------IVIVMEYASRGDLYDYISER--Q 145
Query: 158 KLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPI 217
+L+E E + +A+ H ++HRD+K+EN+L+D + N K+ DFG +++
Sbjct: 146 QLSEREARHFFRQIVSAVHYCHQ--NRVVHRDLKLENILLDANGNIKIADFGLSNL---- 199
Query: 218 VSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTPFE 277
HQ + T +P Y SPE+++ + D W+LG+ LY L+ T PF+
Sbjct: 200 --YHQGKFLQT----FCGSPLYASPEIVNGKPY--TGPEVDSWSLGVLLYILVHGTMPFD 251
Query: 278 ------LTGQFAILHSKYEIPQNGYSSKLINLIIIMLAENPSLRPNIYQVMHH 324
L Q I + Y P S LI +L NP+ R + V H
Sbjct: 252 GHDHKILVKQ--ISNGAYREPPK--PSDACGLIRWLLMVNPTRRATLEDVASH 300
>At1g18390 [T] KOG1187 Serine/threonine protein kinase
Length = 605
Score = 82.4 bits (202), Expect = 3e-15
Identities = 76/288 (26%), Positives = 129/288 (44%), Gaps = 59/288 (20%)
Query: 15 HTAATSAMIPNSHLLSPNT---------QVVVGTH--RCEILEH----------LAEGGF 53
H T+A++P + P+ +++VG H E LE L +GGF
Sbjct: 247 HDTCTNALLPRNISSDPSAKSFDIEKAEELLVGVHIFSYEELEEATNNFDPSKELGDGGF 306
Query: 54 ANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNELRNEVETMKQLRGSP 113
+Y K LK G +KR+ + + RNEVE + LR P
Sbjct: 307 GTVYYGK----------------LKDGRSVAVKRLYDNNFKRAEQFRNEVEILTGLR-HP 349
Query: 114 NIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLA--TKLTEAEILKIMYDV 171
N+V + ++ + D +LL+ E +L D+++ A + L + LKI +
Sbjct: 350 NLVALFGCSSKQSRD------LLLVYEYVANGTLADHLHGPQANPSSLPWSIRLKIAVET 403
Query: 172 SNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTHQDIAVLTNNI 231
++A+ +H + +IHRD+K N+L+D++ N K+ DFG S FP+ TH A
Sbjct: 404 ASALKYLH--ASKIIHRDVKSNNILLDQNFNVKVADFG-LSRLFPMDKTHVSTA------ 454
Query: 232 YVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTPFELT 279
TP Y P D + C ++ KSD+++ + L +L+ ++T
Sbjct: 455 -PQGTPGYVDP---DYHLCYQLSNKSDVYSFAVVLMELISSLPAVDIT 498
>7302458 [T] KOG0574 STE20-like serine/threonine kinase MST
Length = 596
Score = 82.4 bits (202), Expect = 3e-15
Identities = 77/293 (26%), Positives = 132/293 (44%), Gaps = 56/293 (19%)
Query: 43 EILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNELRNE 102
+I+ L EG + ++YK E + I +K +VP E+ L+E+ E
Sbjct: 43 DIMYKLGEGSYGSVYKAVHKE---------------SSSIVAIK--LVPVESDLHEIIKE 85
Query: 103 VETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLTEA 162
+ M+Q SP +V+YY S + +++ + ME C S+ D M + T LTE
Sbjct: 86 ISIMQQC-DSPYVVRYYGSYFKQ-------YDLWICMEYCGAGSVSDIMRLRKKT-LTED 136
Query: 163 EILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTHQ 222
EI I+ D + +H IHRDIK N+L++ + KL DFG +
Sbjct: 137 EIATILSDTLQGLVYLHLRRK--IHRDIKAANILLNTEGYAKLADFG-------VAGQLT 187
Query: 223 DIAVLTNNIYVHTTPQYRSPEMIDL--YRCLPINEKSDIWALGIFLYKLLFYTTPFELTG 280
D N + TP + +PE+I+ Y C+ +DIW+LGI ++ P+ G
Sbjct: 188 DTMAKRNTVI--GTPFWMAPEVIEEIGYDCV-----ADIWSLGITALEMAEGKPPY---G 237
Query: 281 QFAILHSKYEIPQ---------NGYSSKLINLIIIMLAENPSLRPNIYQVMHH 324
+ + + + IPQ + +S++ I+ + L + P R +++ H
Sbjct: 238 EIHPMRAIFMIPQKPPPSFREPDRWSTEFIDFVSKCLVKEPDDRATATELLEH 290
>Hs5454096 [T] KOG0574 STE20-like serine/threonine kinase MST
Length = 487
Score = 81.3 bits (199), Expect = 6e-15
Identities = 76/293 (25%), Positives = 128/293 (42%), Gaps = 56/293 (19%)
Query: 43 EILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNELRNE 102
++LE L EG + ++YK E G I +K+V P E+ L E+ E
Sbjct: 31 DVLEKLGEGSYGSVYKAIHKE---------------TGQIVAIKQV--PVESDLQEIIKE 73
Query: 103 VETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLTEA 162
+ M+Q SP++V+YY S ++ ++ME C S+ D + + T LTE
Sbjct: 74 ISIMQQC-DSPHVVKYYGSYFKNT-------DLWIVMEYCGAGSVSDIIRLRNKT-LTED 124
Query: 163 EILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTHQ 222
EI I+ + +H++ IHRDIK N+L++ + + KL DFG +
Sbjct: 125 EIATILQSTLKGLEYLHFMRK--IHRDIKAGNILLNTEGHAKLADFG-------VAGQLT 175
Query: 223 DIAVLTNNIYVHTTPQYRSPEMIDL--YRCLPINEKSDIWALGIFLYKLLFYTTPFELTG 280
D N + TP + +PE+I Y C+ +DIW+LGI ++ P+
Sbjct: 176 DTMAKRNTVI--GTPFWMAPEVIQEIGYNCV-----ADIWSLGITAIEMAEGKPPY---A 225
Query: 281 QFAILHSKYEIPQNG---------YSSKLINLIIIMLAENPSLRPNIYQVMHH 324
+ + + IP N +S + + L ++P R Q++ H
Sbjct: 226 DIHPMRAIFMIPTNPPPTFRKPELWSDNFTDFVKQCLVKSPEQRATATQLLQH 278
>7299322 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 434
Score = 81.3 bits (199), Expect = 6e-15
Identities = 72/265 (27%), Positives = 125/265 (47%), Gaps = 36/265 (13%)
Query: 67 EMDAGIDSKLLKAGDIACLKRVIVPDENGLNELRNEVETMKQLRGSPNIVQYYDSNASRH 126
++ GI+ + + I +K+ + E L +R EV+ M + PNI+ Y+ +R
Sbjct: 95 KVQLGINKETGQEVAIKTIKKCKIEAEADLVRIRREVQIMSSVH-HPNIIHIYEVFENRE 153
Query: 127 PDGSPGFEILLLMELCPKKSLLDYMNNKLATKLTEAEILKIMYDVSNAIAQMHYLPTPLI 186
+++L+ME L DY++ + LTE E +I V+ A+ H +
Sbjct: 154 -------KMVLVMEFAAGGELYDYLSERKV--LTEEEARRIFRQVATAVYYCH--KHKIC 202
Query: 187 HRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTHQDIAVLTNNIYVHTTPQYRSPEMID 246
HRD+K+EN+L+D+ N K+ DFG + + D +L +P Y SPE+++
Sbjct: 203 HRDLKLENILLDEKGNAKIADFG-------LSNVFDDQRLLGT---FCGSPLYASPEIVE 252
Query: 247 --LYRCLPINEKSDIWALGIFLYKLLFYTTPFELTGQFAILHSKYEIPQNGY-----SSK 299
Y+ + D W+LG+ LY L++ + PF+ + ++ +I Q Y S+
Sbjct: 253 GTPYQ----GPEVDCWSLGVLLYTLVYGSMPFDGSNFKRLVK---QISQGDYYEPRKPSR 305
Query: 300 LINLIIIMLAENPSLRPNIYQVMHH 324
LI ML P R +I Q+ H
Sbjct: 306 ASTLIRDMLTVCPRKRASIEQICSH 330
>At5g38210 [T] KOG1187 Serine/threonine protein kinase
Length = 960
Score = 80.9 bits (198), Expect = 7e-15
Identities = 64/236 (27%), Positives = 111/236 (46%), Gaps = 38/236 (16%)
Query: 46 EHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNELRNEVET 105
+ L +GGF +Y LK G +KR+ + + +NE++
Sbjct: 636 KELGDGGFGTVYY----------------GTLKDGRAVAVKRLFERSLKRVEQFKNEIDI 679
Query: 106 MKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATK--LTEAE 163
+K L+ PN+V Y +RH E+LL+ E +L ++++ A +
Sbjct: 680 LKSLK-HPNLVILYGCT-TRHSR-----ELLLVYEYISNGTLAEHLHGNQAQSRPICWPA 732
Query: 164 ILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTHQD 223
L+I + ++A++ +H + +IHRD+K N+L+D + K+ DFG S FP+ TH
Sbjct: 733 RLQIAIETASALSYLH--ASGIIHRDVKTTNILLDSNYQVKVADFG-LSRLFPMDQTHIS 789
Query: 224 IAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTPFELT 279
A TP Y PE Y+C +NEKSD+++ G+ L +L+ ++T
Sbjct: 790 TA-------PQGTPGYVDPE---YYQCYRLNEKSDVYSFGVVLSELISSKEAVDIT 835
>CE07285 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 615
Score = 80.5 bits (197), Expect = 1e-14
Identities = 79/284 (27%), Positives = 123/284 (42%), Gaps = 52/284 (18%)
Query: 48 LAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNELRNEVETMK 107
L EGGFA+ ++ + L+ + + + + +VI+ +L EVE +
Sbjct: 41 LGEGGFAHCFEFRKLDCNDRLAVKV------------VPKVILLKSTAREKLTREVEIHR 88
Query: 108 QLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLTEAEILKI 167
QL NIVQ+ H + +ELC K SL++ NK LTE E
Sbjct: 89 QL-SHRNIVQF-------HHFFEDSQNVYFTLELCSKNSLMEL--NKQRGPLTEHEARFY 138
Query: 168 MYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTHQDIAVL 227
V+ + +H L +IHRD+K+ N+ +++ K+ DFG + C ++ +
Sbjct: 139 TIQVAEGVKHLHNLQ--IIHRDLKLGNLFLNEHLQVKIGDFGLATFC------EKNEKKM 190
Query: 228 TNNIYVHTTPQYRSPEMIDLYRCLPINEKS-----DIWALGIFLYKLLFYTTPFE----L 278
T TP Y +PE++ NE DIWA+G LY LLF + PFE
Sbjct: 191 TRG----GTPNYIAPEVL--------NETGHAFEVDIWAIGCILYVLLFGSPPFESRRVQ 238
Query: 279 TGQFAILHSKYEIPQNGYSSKLINLIIIMLAENPSLRPNIYQVM 322
I ++ Y +P+N S LI +L P RP V+
Sbjct: 239 ETYVRIKNNDYVVPENA-SPTANRLIRSLLDPVPDRRPTAEAVL 281
>Hs4505373 [V] KOG1826 Ras GTPase activating protein RasGAP/neurofibromin
Length = 445
Score = 80.1 bits (196), Expect = 1e-14
Identities = 70/237 (29%), Positives = 110/237 (45%), Gaps = 31/237 (13%)
Query: 99 LRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNN--KLA 156
L +EV +++L+ PNIV+YYD R + ++ME C L + K
Sbjct: 52 LVSEVNLLRELK-HPNIVRYYDRIIDR-----TNTTLYIVMEYCEGGDLASVITKGTKER 105
Query: 157 TKLTEAEILKIMYDVSNAIAQMHYLPT---PLIHRDIKIENVLVDKDDNFKLCDFGSTSM 213
L E +L++M ++ A+ + H ++HRD+K NV +D N KL DFG +
Sbjct: 106 QYLDEEFVLRVMTQLTLALKECHRRSDGGHTVLHRDLKPANVFLDGKQNVKLGDFGLARI 165
Query: 214 CFPIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYT 273
+ D + + TP Y SPE ++ + NEKSDIW+LG LY+L
Sbjct: 166 L------NHDTSFAKTFV---GTPYYMSPEQMNR---MSYNEKSDIWSLGCLLYELCALM 213
Query: 274 TPF------ELTGQFAILHSKYEIPQNGYSSKLINLIIIMLAENPSLRPNIYQVMHH 324
PF EL G+ I K+ YS +L +I ML RP++ +++ +
Sbjct: 214 PPFTAFSQKELAGK--IREGKFRRIPYRYSDELNEIITRMLNLKDYHRPSVEEILEN 268
>At1g18160 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 990
Score = 80.1 bits (196), Expect = 1e-14
Identities = 67/259 (25%), Positives = 125/259 (47%), Gaps = 30/259 (11%)
Query: 80 GDIACLKRVIVPDENG--LNELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILL 137
G +K+ I D G L E R+EV M++LR PNIV + + +R P+ S +
Sbjct: 734 GTAVAVKKFIDQDITGEALEEFRSEVRMMRRLR-HPNIVLFMGA-VTRPPNLS------I 785
Query: 138 LMELCPKKSLLDYMNNKLATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLV 197
+ E P+ SL ++ +L E + L++ D + + +H ++HRD+K N+LV
Sbjct: 786 VTEFLPRGSLYRLIHRP-NNQLDERKRLRMALDAARGMNYLHSCNPVIVHRDLKSPNLLV 844
Query: 198 DKDDNFKLCDFGSTSMCFPIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKS 257
DK+ K+CDFG + M ++ ++ T ++ +PE++ R P +EK
Sbjct: 845 DKNWVVKVCDFGLSRM---------KVSTYLSSKSTAGTAEWMAPEVL---RNEPADEKC 892
Query: 258 DIWALGIFLYKLLFY------TTPFELTGQFAILHSKYEIPQNGYSSKLINLIIIMLAEN 311
D+++ G+ L++L P ++ G H + +IP+ + ++I +
Sbjct: 893 DVYSYGVILWELFTLQQPWGKMNPMQVVGAVGFQHRRLDIPE-FVDPGIADIIRKCWQTD 951
Query: 312 PSLRPNIYQVMHHVCSILK 330
P LRP+ ++M + + K
Sbjct: 952 PRLRPSFGEIMDSLKQLQK 970
>7296450 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 769
Score = 80.1 bits (196), Expect = 1e-14
Identities = 82/299 (27%), Positives = 135/299 (44%), Gaps = 53/299 (17%)
Query: 43 EILEHLAEGGFANIYKVKFLELTNEMDAG-IDSKLLKAGDIACLKRVIVPDENGLNELRN 101
E+ L +GGFA +YK + L ++ ID KL++ + N +R
Sbjct: 15 EVQHLLGKGGFATVYKARCLHTHQDVAIKMIDKKLIQGTGLT-------------NRVRQ 61
Query: 102 EVETMKQLRGSPNIVQYY----DSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLAT 157
EVE +L+ P+++Q Y D+N + L++EL L YMN+ +A
Sbjct: 62 EVEIHSRLK-HPSVLQLYTFFQDANY-----------VYLVLELAHNGELHRYMNH-IAR 108
Query: 158 KLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPI 217
TE E I+ V + +H ++HRDI + N+L+ ++ + K+ DFG +
Sbjct: 109 PFTETEAASILKQVVAGLLYLH--SHNIMHRDISLSNLLLSREMHVKIADFGLATQLKRP 166
Query: 218 VSTHQDIAVLTNNIYVHTTPQYRSPEMID-LYRCLPINEKSDIWALGIFLYKLLFYTTPF 276
H + TP Y SPE++ LP +D+W++G LY LL PF
Sbjct: 167 DERHMTMC---------GTPNYISPEVVSRTSHGLP----ADVWSVGCMLYTLLVGRPPF 213
Query: 277 ELTGQFAILH----SKYEIPQNGYSSKLINLIIIMLAENPSLRPNIYQVMHHVCSILKC 331
E + L+ S+Y +P + S + +LI +L + P R + V+ H +LKC
Sbjct: 214 ETDAVQSTLNKVVMSEYIMPAH-LSYEAQDLINKLLKKLPHERITLEAVLCHP-FMLKC 270
>7290841 [D] KOG0591 NIMA (never in mitosis)-related G2-specific
serine/threonine protein kinase
Length = 735
Score = 79.3 bits (194), Expect = 2e-14
Identities = 77/292 (26%), Positives = 132/292 (44%), Gaps = 43/292 (14%)
Query: 43 EILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNELRNE 102
E+L + G F YKV+ + T E+ A K + ++ DE + L +E
Sbjct: 20 EVLAVMGNGSFGTCYKVRD-KSTGELFAW---KGMNYDEL---------DEAKCDALVSE 66
Query: 103 VETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATK--LT 160
+ ++QL+ PNIVQYY +R + ++ME C L + + +
Sbjct: 67 ISVLRQLQ-HPNIVQYYHHLVNREAKS-----VYIVMECCAGGDLAQIVQRARSQRQRFE 120
Query: 161 EAEILKIMYDVSNAIAQMHY-LPT-PLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIV 218
E I ++++ + A+ H +P ++HRDIK N+ +D N KL DFG M
Sbjct: 121 EPYIWRVLFQLCRALQVCHNKIPNGTILHRDIKPANIFLDAAGNAKLGDFGLARM----- 175
Query: 219 STHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTPF-- 276
+D + + + TP Y SPE++ + + KSD+WA+G +Y++ PF
Sbjct: 176 -LRRDQSFAASFV---GTPHYMSPELV---KGRKYDRKSDVWAVGCLVYEMCALRPPFRG 228
Query: 277 ----ELTGQFAILHSKYEIPQNGYSSKLINLIIIMLAENPSLRPNIYQVMHH 324
+L+ + A ++ YS+ L +I MLA + RP I ++ H
Sbjct: 229 RAFDQLSEKIA--QGEFSRIPAIYSTDLQEIIAFMLAVDHEQRPGIEVIIRH 278
>CE23001 [R] KOG0589 Serine/threonine protein kinase
Length = 579
Score = 79.0 bits (193), Expect = 3e-14
Identities = 85/329 (25%), Positives = 142/329 (42%), Gaps = 50/329 (15%)
Query: 28 LLSPNTQVVVGTHRCEILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKR 87
+ +PN + +R E + + +G F + + E DS L+ +I
Sbjct: 157 ITNPNPRATSAQNRYERIRTVGKGAFGSAVLYRRRE---------DSSLVIIKEI----N 203
Query: 88 VIVPDENGLNELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMEL-CPKKS 146
+ D + NEV + ++ PNI+ YYDS E +L++E+
Sbjct: 204 MYDLDSSQRRLALNEVSLLSRIE-HPNIIAYYDSFEE---------EGVLMIEMEYADGG 253
Query: 147 LLDYMNNKLATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLC 206
L M ++ L E +I +M + +A+A +H ++HRD+K NV + +D K+
Sbjct: 254 TLAQMLSRTQNLLDEEQIGDMMIQMCSAVAYLH--ENSVLHRDLKTANVFLTRDSFVKIG 311
Query: 207 DFGSTSMCFPIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFL 266
DFG + I+ T + V TP Y SPEM + NEKSD+WALG L
Sbjct: 312 DFGISK----IMGTE---TLAQGAKTVVGTPYYISPEMCS---GVSYNEKSDMWALGCIL 361
Query: 267 YKLLFYTTPFELTGQFAILHS----KYEIPQNGYSSKLINLIIIMLAENPSLRPNIYQVM 322
Y++ FE A+++S Y + YS+++ +I +L +P RP+ Q +
Sbjct: 362 YEMCCLKKAFEGDNLPALVNSIMTCAYTPVKGPYSAEMKMVIRELLQLDPQKRPSAPQAL 421
Query: 323 ----------HHVCSILKCDVPFTDKYEL 341
H ++ V FT Y+L
Sbjct: 422 KMLRPSENRHRHTSGSMRSSVSFTTLYDL 450
>CE22877 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 632
Score = 78.6 bits (192), Expect = 4e-14
Identities = 73/281 (25%), Positives = 133/281 (46%), Gaps = 42/281 (14%)
Query: 41 RCEILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNELR 100
R E + L +GGFA+ Y+++ + T E+ AG + + ++ + +++
Sbjct: 35 RYEKGKFLGKGGFAHCYELRN-KSTGELFAG-----------KVVPKALLIKQYQRDKMA 82
Query: 101 NEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLT 160
EV+ + L+ N+V+ Y + + + +ELCP++SL++ + A +T
Sbjct: 83 QEVQIHRNLQHR-NVVKLYHFFEDKS-------NVYITLELCPRRSLMELHKRRKA--VT 132
Query: 161 EAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVST 220
E E Y + + +H L ++HRD+K+ N+ ++ + K+ DFG + C
Sbjct: 133 EPEARYFTYQIVEGVLYLHNLK--IVHRDLKLGNLFLNDELQVKIGDFGLATTC------ 184
Query: 221 HQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTPFELTG 280
D T + TP Y +PE+++ + + + D+WA+G LY LLF PFE
Sbjct: 185 DNDERKKT----LCGTPNYIAPEVLNK---IGHSFEVDLWAIGCILYILLFGHPPFESKS 237
Query: 281 ----QFAILHSKYEIPQNGYSSKLINLIIIMLAENPSLRPN 317
I ++ Y IP + S+ LI ++L PS RPN
Sbjct: 238 LEETYSRIKNNNYVIPTSA-SAAASQLIRVLLDPVPSRRPN 277
>7292249 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 979
Score = 78.6 bits (192), Expect = 4e-14
Identities = 71/289 (24%), Positives = 125/289 (42%), Gaps = 35/289 (12%)
Query: 43 EILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNELRNE 102
E++E + G + +YK + K G +A +K + V ++ E++ E
Sbjct: 33 ELIEVVGNGTYGQVYK---------------GRHTKTGQLAAIKVMDVTEDEE-EEIKLE 76
Query: 103 VETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLTEA 162
+ +K+ NI YY + + P G ++ L+ME C S+ D + + L E
Sbjct: 77 INVLKKYSNHRNIATYYGAFIKKSPPGKDD-QLWLVMEYCGAGSVTDLVKSTKGQSLKEE 135
Query: 163 EILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTHQ 222
I I ++ ++ +H +IHRDIK +NVL+ + KL DFG VS
Sbjct: 136 WIAYICREILRGLSYLH--SNKVIHRDIKGQNVLLTDNAEVKLVDFG--------VSAQL 185
Query: 223 DIAVLTNNIYVHTTPQYRSPEMI--DLYRCLPINEKSDIWALGIFLYKLLFYTTPF---- 276
D + N ++ TP + +PE+I D + +SD+W+LGI ++ P
Sbjct: 186 DRTIGRRNTFI-GTPYWMAPEVIACDENPDATYDNRSDLWSLGITALEMAESQPPLCDLH 244
Query: 277 ELTGQFAI-LHSKYEIPQNGYSSKLINLIIIMLAENPSLRPNIYQVMHH 324
+ F I +S + +S K I +L ++ RP ++ H
Sbjct: 245 PMRALFLIPRNSPPRLKSKKWSKKFHGFIDTVLVKDYHQRPYTENLLKH 293
>7302511 [T] KOG0576 Mitogen-activated protein kinase kinase kinase kinase
(MAP4K) germinal center kinase family
Length = 1218
Score = 78.2 bits (191), Expect = 5e-14
Identities = 74/325 (22%), Positives = 141/325 (42%), Gaps = 46/325 (14%)
Query: 25 NSHLLSPNTQVVVGTHRCEILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIAC 84
N+++LS + E+++ + G + ++YK +K +++ ++A
Sbjct: 9 NANMLSSDISRRNPQDEYELIQKIGSGTYGDVYK---------------AKRIQSNELAA 53
Query: 85 LKRVIVPDENGLNELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPK 144
+K + + + + ++ E+ M+ R PNI+ YY S R ++ + ME C
Sbjct: 54 IKVIKLEPSDDIQIIQQEIIMMRDCR-HPNIIAYYGSYLRRD-------KLWICMEFCGG 105
Query: 145 KSLLDYMNNKLATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFK 204
SL D ++ LTE +I + + + +H + +HRDIK N+L+ + + K
Sbjct: 106 GSLQDIY--QVTGPLTEVQIAYMCRETLKGLEYLHSMGK--MHRDIKGANILLTEYGDVK 161
Query: 205 LCDFGSTSMCFPIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGI 264
L DFG ++ Q A + TP + +PE+ + R N+ DIWA GI
Sbjct: 162 LADFGVSA---------QITATINKRKSFIGTPYWMAPEVAAVERKGGYNQLCDIWACGI 212
Query: 265 FLYKLLFYTTPF----ELTGQFAILHSKYEIP----QNGYSSKLINLIIIMLAENPSLRP 316
+L P + F + S ++ P ++ +S N I L +NP RP
Sbjct: 213 TAIELAELQPPMFDLHPMRALFLMSKSGFKPPTLNNKDKWSPTFHNFIKTALTKNPKKRP 272
Query: 317 NIYQVMHHVCSILKCDVPFTDKYEL 341
+++ H ++C++ EL
Sbjct: 273 TAERLLQH--PFVQCEMSLRVAKEL 295
>Hs5453882 [G] KOG0599 Phosphorylase kinase gamma subunit
Length = 387
Score = 77.8 bits (190), Expect = 6e-14
Identities = 70/252 (27%), Positives = 117/252 (45%), Gaps = 45/252 (17%)
Query: 91 PDENGLNELRN----EVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKS 146
P+E + ELR EV+ ++++ G PNI+Q D+ + L+ +L +
Sbjct: 61 PEE--VRELREATLKEVDILRKVSGHPNIIQLKDTYETNT-------FFFLVFDLMKRGE 111
Query: 147 LLDYMNNKLATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLC 206
L DY+ K+ L+E E KIM + I +H L ++HRD+K EN+L+D + N KL
Sbjct: 112 LFDYLTEKVT--LSEKETRKIMRALLEVICTLHKLN--IVHRDLKPENILLDDNMNIKLT 167
Query: 207 DFGSTSMCFPIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINE-------KSDI 259
DFG + P + V TP Y +PE+I+ +NE + D+
Sbjct: 168 DFGFSCQLEPGERLRE----------VCGTPSYLAPEIIE----CSMNEDHPGYGKEVDM 213
Query: 260 WALGIFLYKLLFYTTPFELTGQFAIL------HSKYEIPQ-NGYSSKLINLIIIMLAENP 312
W+ G+ +Y LL + PF Q +L + ++ P+ + YS + +L+ L P
Sbjct: 214 WSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFGSPEWDDYSDTVKDLVSRFLVVQP 273
Query: 313 SLRPNIYQVMHH 324
R + + H
Sbjct: 274 QNRYTAEEALAH 285
>At5g58940 [T] KOG1187 Serine/threonine protein kinase
Length = 466
Score = 77.8 bits (190), Expect = 6e-14
Identities = 62/237 (26%), Positives = 110/237 (46%), Gaps = 36/237 (15%)
Query: 45 LEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPD--ENGLNELRNE 102
+ + EGGF ++K K L G I +KR + ++ L E +NE
Sbjct: 146 VHQIGEGGFGTVFKGK----------------LDDGTIVAIKRARKNNYGKSWLLEFKNE 189
Query: 103 VETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLTEA 162
+ T+ ++ N+V+ Y H D E ++++E +L ++++ +L A
Sbjct: 190 IYTLSKIEHM-NLVKLY--GFLEHGD-----EKVIVVEYVANGNLREHLDGLRGNRLEMA 241
Query: 163 EILKIMYDVSNAIAQMH-YLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTH 221
E L+I DV++A+ +H Y +P+IHRDIK N+L+ K+ DFG +
Sbjct: 242 ERLEIAIDVAHALTYLHTYTDSPIIHRDIKASNILITNKLRAKVADFGFARL------VS 295
Query: 222 QDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTPFEL 278
+D+ + V + Y P D R + +KSD+++ G+ L ++L P EL
Sbjct: 296 EDLGATHISTQVKGSAGYVDP---DYLRTFQLTDKSDVYSFGVLLVEILTGRRPIEL 349
>At1g25390 [T] KOG1187 Serine/threonine protein kinase
Length = 629
Score = 77.8 bits (190), Expect = 6e-14
Identities = 79/307 (25%), Positives = 136/307 (43%), Gaps = 62/307 (20%)
Query: 48 LAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNELRNEVETMK 107
L +GGF +Y K ++ G +KR+ + L + NE+E +
Sbjct: 297 LGDGGFGTVYYGK----------------VRDGREVAVKRLYEHNYRRLEQFMNEIEILT 340
Query: 108 QLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYM---NNKLATKLTEAEI 164
+L N+V Y + R E+LL+ E P ++ D++ N LT +
Sbjct: 341 RLHHK-NLVSLYGCTSRRSR------ELLLVYEFIPNGTVADHLYGENTPHQGFLTWSMR 393
Query: 165 LKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTHQDI 224
L I + ++A+A +H + +IHRD+K N+L+D++ K+ DFG S P TH
Sbjct: 394 LSIAIETASALAYLH--ASDIIHRDVKTTNILLDRNFGVKVADFG-LSRLLPSDVTHVST 450
Query: 225 AVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTPFELT----- 279
A TP Y PE +RC + +KSD+++ G+ L +L+ +++
Sbjct: 451 A-------PQGTPGYVDPE---YHRCYHLTDKSDVYSFGVVLVELISSKPAVDISRCKSE 500
Query: 280 ---GQFAI----LHSKYE-IPQN-GYSSK---------LINLIIIMLAENPSLRPNIYQV 321
AI H+ +E I QN GY++ + L L ++ ++RP + QV
Sbjct: 501 INLSSLAINKIQNHATHELIDQNLGYATNEGVRKMTTMVAELAFQCLQQDNTMRPTMEQV 560
Query: 322 MHHVCSI 328
+H + I
Sbjct: 561 VHELKGI 567
>7302570 [R] KOG0586 Serine/threonine protein kinase
Length = 702
Score = 77.8 bits (190), Expect = 6e-14
Identities = 85/307 (27%), Positives = 144/307 (46%), Gaps = 46/307 (14%)
Query: 23 IPNSHLLSPNTQVVVGTHRCEILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDI 82
+P++ +S + + VG + E + + +G FA + K+ +T A +K D
Sbjct: 24 VPSTSKISVDKLLRVGYYELE--KTIGKGNFA-VVKLATNIVTKTKVA------IKIIDK 74
Query: 83 ACLKRVIVPDENGLNELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELC 142
CL +E LN+ E+ +K LR P+I + Y+ S+ I L+ E
Sbjct: 75 TCL------NEEYLNKTFREIAILKSLR-HPHITRLYEVMESQSM-------IYLVTEYA 120
Query: 143 PKKSLLDYMNNKLATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDN 202
P + D++ ++ E E ++ + +A+ H ++HRD+K ENVL+DKD N
Sbjct: 121 PNGEIFDHLVAN--GRMKEPEAARVFTQLVSAVHYCHR--RGVVHRDLKAENVLLDKDMN 176
Query: 203 FKLCDFGSTSMCFPIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPIN-EKSDIWA 261
KL DFG + + +++ A L +P Y +PE +++ L + KSDIW+
Sbjct: 177 IKLADFGFS-------NHYEEGATLKTWC---GSPPYAAPE---VFQGLEYDGPKSDIWS 223
Query: 262 LGIFLYKLLFYTTPFE----LTGQFAILHSKYEIPQNGYSSKLINLIIIMLAENPSLRPN 317
LG+ LY L+ PF+ L + ++ K+ IP S + LI ML P R
Sbjct: 224 LGVVLYALVCGALPFDGKTILELKSRVVLGKFRIP-FFMSQECEQLIRNMLVVEPDRRYT 282
Query: 318 IYQVMHH 324
I Q++ H
Sbjct: 283 IKQIIKH 289
>Hs17445015 [KIT] KOG2345 Serine/threonine protein kinase/TGF-beta stimulated
factor
Length = 305
Score = 77.4 bits (189), Expect = 8e-14
Identities = 73/297 (24%), Positives = 132/297 (43%), Gaps = 39/297 (13%)
Query: 35 VVVGTHRCEILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDEN 94
V++ R ++ L EGGF+ + V+ L G LKR++ ++
Sbjct: 13 VIIDNKRYLFIQKLGEGGFSYVDLVEGLH---------------DGHFYALKRILCHEQQ 57
Query: 95 GLNELRNEVETMKQLRGSPNIVQYYD----SNASRHPDGSPGFEILLLMELCPKKSLLDY 150
E + E + M +L PNI++ ++H E LL+ + +L +
Sbjct: 58 DREEAQREAD-MHRLFNHPNILRLVAYCLRERGAKH-------EAWLLLPFFKRGTLWNE 109
Query: 151 MNNKLATK---LTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCD 207
+ +L K LTE +IL ++ + + +H HRD+K N+L+ + L D
Sbjct: 110 IE-RLKDKGNFLTEDQILWLLLGICRGLEAIH--AKGYAHRDLKPTNILLGDEGQPVLMD 166
Query: 208 FGSTSMCFPIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLY 267
GS + V + L + T YR+PE+ + I+E++D+W+LG LY
Sbjct: 167 LGSMNQACIHVEGSRQALTLQDWAAQRCTISYRAPELFSVQSHCVIDERTDVWSLGCVLY 226
Query: 268 KLLFYTTPFELTGQ-----FAILHSKYEIPQN-GYSSKLINLIIIMLAENPSLRPNI 318
++F P+++ Q + ++ IPQ+ +SS L L+ M+ +P RP+I
Sbjct: 227 AMMFGEGPYDMVFQKGDSVALAVQNQLSIPQSPRHSSALRQLLNSMMTVDPHQRPHI 283
>At1g73660 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 1030
Score = 77.4 bits (189), Expect = 8e-14
Identities = 67/251 (26%), Positives = 119/251 (46%), Gaps = 30/251 (11%)
Query: 80 GDIACLKRVIVPDENG--LNELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILL 137
G +K+ + D G L E R+EV MK+LR PNIV + + +R P+ S +
Sbjct: 769 GTEVAVKKFLDQDLTGEALEEFRSEVRIMKKLR-HPNIVLFMGA-VTRPPNLS------I 820
Query: 138 LMELCPKKSLLDYMNNKLATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLV 197
+ E P+ SL ++ +L E L++ D + + +H ++HRD+K N+LV
Sbjct: 821 VTEFLPRGSLYRLIHRP-NNQLDERRRLRMALDAARGMNYLHSCNPMIVHRDLKSPNLLV 879
Query: 198 DKDDNFKLCDFGSTSMCFPIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKS 257
DK+ K+CDFG + M + + A T ++ +PE++ R P +EK
Sbjct: 880 DKNWVVKVCDFGLSRMKHSTYLSSKSTA---------GTAEWMAPEVL---RNEPADEKC 927
Query: 258 DIWALGIFLYKLLFY------TTPFELTGQFAILHSKYEIPQNGYSSKLINLIIIMLAEN 311
D+++ G+ L++L P ++ G H + +IP + + +LI +
Sbjct: 928 DVYSYGVILWELFTLQQPWGKMNPMQVVGAVGFQHRRLDIP-DFVDPAIADLISKCWQTD 986
Query: 312 PSLRPNIYQVM 322
LRP+ ++M
Sbjct: 987 SKLRPSFAEIM 997
>At1g08720 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 1015
Score = 77.4 bits (189), Expect = 8e-14
Identities = 80/336 (23%), Positives = 146/336 (42%), Gaps = 57/336 (16%)
Query: 4 SDTISR---PNSVAHTAATSAMIPNSHLLSPNTQVVVGTHRCEI-------LEHLAEGGF 53
SD IS P H + +S++ S+ P CEI E + G +
Sbjct: 703 SDDISTGCDPRLKDHESTSSSLDSTSYRNDPQVLDDADVGECEIPWNDLVIAERIGLGSY 762
Query: 54 ANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENG--LNELRNEVETMKQLRG 111
+Y + G +K+ + D +G L E R+EV M++LR
Sbjct: 763 GEVYHADW-----------------HGTEVAVKKFLDQDFSGAALAEFRSEVRIMRRLR- 804
Query: 112 SPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLTEAEILKIMYDV 171
PN+V ++ +R P+ S ++ E P+ SL ++ + + E +K+ DV
Sbjct: 805 HPNVV-FFLGAVTRPPNLS------IVTEFLPRGSLYRILHRP-KSHIDERRRIKMALDV 856
Query: 172 SNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTHQDIAVLTNNI 231
+ + +H ++HRD+K N+LVD + N K+ DFG + + + + A
Sbjct: 857 AMGMNCLHTSTPTIVHRDLKTPNLLVDNNWNVKVGDFGLSRLKHNTFLSSKSTA------ 910
Query: 232 YVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFY------TTPFELTGQFAIL 285
TP++ +PE++ R P NEK D+++ G+ L++L P ++ G
Sbjct: 911 ---GTPEWMAPEVL---RNEPSNEKCDVYSFGVILWELATLRLPWRGMNPMQVVGAVGFQ 964
Query: 286 HSKYEIPQNGYSSKLINLIIIMLAENPSLRPNIYQV 321
+ + EIP+ + +I+ +P+LRP+ Q+
Sbjct: 965 NRRLEIPKE-LDPVVGRIILECWQTDPNLRPSFAQL 999
>Hs7661974 [T] KOG0583 Serine/threonine protein kinase
Length = 651
Score = 77.0 bits (188), Expect = 1e-13
Identities = 79/286 (27%), Positives = 134/286 (46%), Gaps = 41/286 (14%)
Query: 43 EILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNELRNE 102
E+ E + GGFA + K+ LT EM A +K D K + D L ++ E
Sbjct: 12 ELHETIGTGGFAKV-KLACHILTGEMVA------IKIMD----KNTLGSD---LPRIKTE 57
Query: 103 VETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLTEA 162
+E +K LR +I Q Y + + +I +++E CP L DY+ ++ +L+E
Sbjct: 58 IEALKNLRHQ-HICQLYHVLETAN-------KIFMVLEYCPGGELFDYIISQ--DRLSEE 107
Query: 163 EILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTHQ 222
E + + +A+A +H HRD+K EN+L D+ KL DFG + P +
Sbjct: 108 ETRVVFRQIVSAVAYVH--SQGYAHRDLKPENLLFDEYHKLKLIDFGLCAK--PKGNKDY 163
Query: 223 DIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTPFELTGQF 282
+ ++ Y +PE+I L ++D+W++GI LY L+ PF+
Sbjct: 164 HLQTCCGSL------AYAAPELIQGKSYL--GSEADVWSMGILLYVLMCGFLPFDDDNVM 215
Query: 283 A----ILHSKYEIPQNGYSSKLINLIIIMLAENPSLRPNIYQVMHH 324
A I+ KY++P+ S I L+ ML +P R ++ +++H
Sbjct: 216 ALYKKIMRGKYDVPK-WLSPSSILLLQQMLQVDPKKRISMKNLLNH 260
>Hs5454094 [T] KOG0574 STE20-like serine/threonine kinase MST
Length = 491
Score = 77.0 bits (188), Expect = 1e-13
Identities = 74/293 (25%), Positives = 127/293 (43%), Gaps = 56/293 (19%)
Query: 43 EILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNELRNE 102
++LE L EG + +++K E +G + +K+V P E+ L E+ E
Sbjct: 28 DVLEKLGEGSYGSVFKAIHKE---------------SGQVVAIKQV--PVESDLQEIIKE 70
Query: 103 VETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLTEA 162
+ M+Q SP +V+YY S ++ ++ME C S+ D + + T L E
Sbjct: 71 ISIMQQC-DSPYVVKYYGSYFKNT-------DLWIVMEYCGAGSVSDIIRLRNKT-LIED 121
Query: 163 EILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTHQ 222
EI I+ + +H++ IHRDIK N+L++ + + KL DFG +
Sbjct: 122 EIATILKSTLKGLEYLHFMRK--IHRDIKAGNILLNTEGHAKLADFG-------VAGQLT 172
Query: 223 DIAVLTNNIYVHTTPQYRSPEMIDL--YRCLPINEKSDIWALGIFLYKLLFYTTPFELTG 280
D N + TP + +PE+I Y C+ +DIW+LGI ++ P+
Sbjct: 173 DTMAKRNTVI--GTPFWMAPEVIQEIGYNCV-----ADIWSLGITSIEMAEGKPPY---A 222
Query: 281 QFAILHSKYEIPQNG---------YSSKLINLIIIMLAENPSLRPNIYQVMHH 324
+ + + IP N +S + + L +NP R Q++ H
Sbjct: 223 DIHPMRAIFMIPTNPPPTFRKPELWSDDFTDFVKKCLVKNPEQRATATQLLQH 275
>Hs4505837 [KIT] KOG2345 Serine/threonine protein kinase/TGF-beta stimulated
factor
Length = 310
Score = 77.0 bits (188), Expect = 1e-13
Identities = 73/297 (24%), Positives = 131/297 (43%), Gaps = 39/297 (13%)
Query: 35 VVVGTHRCEILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDEN 94
V++ R ++ L EGGF+ + V+ L G LKR++ ++
Sbjct: 13 VIIDNKRYLFIQKLGEGGFSYVDLVEGLH---------------DGHFYALKRILCHEQQ 57
Query: 95 GLNELRNEVETMKQLRGSPNIVQYYD----SNASRHPDGSPGFEILLLMELCPKKSLLDY 150
E + E + M +L PNI++ ++H E LL+ + +L +
Sbjct: 58 DREEAQREAD-MHRLFNHPNILRLVAYCLRERGAKH-------EAWLLLPFFKRGTLWNE 109
Query: 151 MNNKLATK---LTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCD 207
+ +L K LTE +IL ++ + + +H HRD+K N+L+ + L D
Sbjct: 110 IE-RLKDKGNFLTEDQILWLLLGICRGLEAIH--AKGYAHRDLKPTNILLGDEGQPVLMD 166
Query: 208 FGSTSMCFPIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLY 267
GS + V + L + T YR+PE+ + I E++D+W+LG LY
Sbjct: 167 LGSMNQACIHVEGSRQALTLQDWAAQRCTISYRAPELFSVQSHCVIGERTDVWSLGCVLY 226
Query: 268 KLLFYTTPFELTGQ-----FAILHSKYEIPQN-GYSSKLINLIIIMLAENPSLRPNI 318
++F P+++ Q + ++ IPQ+ +SS L L+ M+ +P RP+I
Sbjct: 227 AMMFGEGPYDMVFQKGDSVALAVQNQLSIPQSPRHSSALRQLLNSMMTVDPHQRPHI 283
>Hs16178962 [T] KOG0574 STE20-like serine/threonine kinase MST
Length = 491
Score = 77.0 bits (188), Expect = 1e-13
Identities = 74/293 (25%), Positives = 127/293 (43%), Gaps = 56/293 (19%)
Query: 43 EILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNELRNE 102
++LE L EG + +++K E +G + +K+V P E+ L E+ E
Sbjct: 28 DVLEKLGEGSYGSVFKAIHKE---------------SGQVVAIKQV--PVESDLQEIIKE 70
Query: 103 VETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLTEA 162
+ M+Q SP +V+YY S ++ ++ME C S+ D + + T L E
Sbjct: 71 ISIMQQC-DSPYVVKYYGSYFKNT-------DLWIVMEYCGAGSVSDIIRLRNKT-LIED 121
Query: 163 EILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTHQ 222
EI I+ + +H++ IHRDIK N+L++ + + KL DFG +
Sbjct: 122 EIATILKSTLKGLEYLHFMRK--IHRDIKAGNILLNTEGHAKLADFG-------VAGQLT 172
Query: 223 DIAVLTNNIYVHTTPQYRSPEMIDL--YRCLPINEKSDIWALGIFLYKLLFYTTPFELTG 280
D N + TP + +PE+I Y C+ +DIW+LGI ++ P+
Sbjct: 173 DTMAKRNTVI--GTPFWMAPEVIQEIGYNCV-----ADIWSLGITSIEMAEGKPPY---A 222
Query: 281 QFAILHSKYEIPQNG---------YSSKLINLIIIMLAENPSLRPNIYQVMHH 324
+ + + IP N +S + + L +NP R Q++ H
Sbjct: 223 DIHPMRAIFMIPTNPPPTFRKPELWSDDFTDFVKKCLVKNPEQRATATQLLQH 275
>CE00847 [T] KOG0583 Serine/threonine protein kinase
Length = 622
Score = 77.0 bits (188), Expect = 1e-13
Identities = 63/247 (25%), Positives = 124/247 (49%), Gaps = 37/247 (14%)
Query: 96 LNELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKL 155
+N+ RNE++ +++L P+I + + ++ +I L+MEL L Y+ K
Sbjct: 66 VNKTRNEIDNLQKLT-HPHITRLFRVISTPS-------DIFLVMELVSGGELFSYITRKG 117
Query: 156 ATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCF 215
A + E+ + + + ++ H ++HRD+K EN+L+D + N K+ DFG ++
Sbjct: 118 ALPIRESR--RYFQQIISGVSYCHN--HMIVHRDLKPENLLLDANKNIKIADFGLSN--- 170
Query: 216 PIVSTHQDIAVLTNNIYVHT---TPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFY 272
+T+ + T +P Y +PE+I L + + D+W+ G+ LY +L
Sbjct: 171 ----------YMTDGDLLSTACGSPNYAAPELIS--NKLYVGPEVDLWSCGVILYAMLCG 218
Query: 273 TTPFE---LTGQFAILHS-KYEIPQNGYSSKLINLIIIMLAENPSLRPNIYQVMHHVCSI 328
T PF+ + FA + S +Y +P + + +LI ML +P R ++ ++++H S
Sbjct: 219 TLPFDDQNVPTLFAKIKSGRYTVPYS-MEKQAADLISTMLQVDPVKRADVKRIVNH--SW 275
Query: 329 LKCDVPF 335
+ D+P+
Sbjct: 276 FRIDLPY 282
>7291778 [T] KOG0579 Ste20-like serine/threonine protein kinase
Length = 1726
Score = 77.0 bits (188), Expect = 1e-13
Identities = 72/278 (25%), Positives = 130/278 (45%), Gaps = 33/278 (11%)
Query: 60 KFLELTNEMDAGIDSKLLKAGD-----IACLKRVIVPDENGLNELRNEVETMKQLRGSPN 114
+F E+ E+ G K+ KA A K + DE L++ E++ + +++ PN
Sbjct: 35 EFWEMVGELGDGAFGKVYKAQHKEQKRFAAAKMCQLEDEENLSDHMVEIDILSEIK-HPN 93
Query: 115 IVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLTEAEILKIMYDVSNA 174
IV+ Y++ S ++ +L+E C +L D + +L LTE +I + ++
Sbjct: 94 IVELYEAF-------SIDDKLWMLIEYCDGGAL-DSIMVELEKPLTEPQIAYVCKHMTEG 145
Query: 175 IAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTHQDIAVLTNNIYVH 234
+ +H +IHRD+K NVL+ + KL DFG VS + ++ ++
Sbjct: 146 LTFLHR--NKVIHRDLKAGNVLLTMEGGVKLADFG--------VSAKNKHTMQKHDTFI- 194
Query: 235 TTPQYRSPEMI--DLYRCLPINEKSDIWALGIFLYKLLFYTTPFELTGQFAIL--HSKYE 290
TP + +PE++ + +R P + K DIW+LGI L +L P +L K E
Sbjct: 195 GTPYWMAPELVLCETFRDNPYDHKVDIWSLGITLIELAQMEPPNSEMSPMRVLLKIQKSE 254
Query: 291 IPQ----NGYSSKLINLIIIMLAENPSLRPNIYQVMHH 324
P+ + +S + + + L ++P +RP +M H
Sbjct: 255 PPKLEQPSRWSKEFNDFLKKSLVKDPQVRPTTDVLMQH 292
>CE27894_1 [R] KOG0589 Serine/threonine protein kinase
Length = 1011
Score = 77.0 bits (188), Expect = 1e-13
Identities = 71/284 (25%), Positives = 128/284 (45%), Gaps = 29/284 (10%)
Query: 43 EILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNELRNE 102
E+L+ L G F +Y V+ ++ + +KLL +I + ++ +E
Sbjct: 432 ELLDQLGAGAFGCVYTVRKKAQSHSENP---AKLLALKEIFMTNLNDRESDKSFGDMISE 488
Query: 103 VETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLTEA 162
V+ +KQ PNIV+Y H + ++ L++ C + L+ M K E
Sbjct: 489 VKIIKQQLRHPNIVRYRRIFVENHRL----YIVMDLIQGCSLRDLIITMKEKKGN-FEEK 543
Query: 163 EILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTHQ 222
+I ++ + A+ +H ++HRD+K N+++ D+ + DFG P
Sbjct: 544 KIWAMVVQMMLALRYLHK-EKQIVHRDLKPNNIMMTTDERVVITDFGLAKQKGPEYLKSA 602
Query: 223 DIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKL-----LFYTTPFE 277
++ Y PE++ + LP EK+DIW+ G +Y++ +F++T
Sbjct: 603 AGTII-----------YSCPEIV---QNLPYGEKADIWSFGCCIYEMCQLQPVFHSTNM- 647
Query: 278 LTGQFAILHSKYEIPQNGYSSKLINLIIIMLAENPSLRPNIYQV 321
LT I+ +KY+ +S L LI LA +PS RP+I +V
Sbjct: 648 LTLAMQIVEAKYDPLNEMWSDDLRFLITSCLAPDPSARPDILKV 691
>YDR477w [T] KOG0583 Serine/threonine protein kinase
Length = 633
Score = 76.6 bits (187), Expect = 1e-13
Identities = 83/321 (25%), Positives = 149/321 (45%), Gaps = 56/321 (17%)
Query: 25 NSHLLSPNTQVVVGTH--RCEILEHLAEGGFANIYKVKFLELTNEMDAG--IDSKLLKAG 80
NS L +P + + G H +I++ L EG F + K+ + T + A I+ K+L
Sbjct: 36 NSTLNNPKSSLADGAHIGNYQIVKTLGEGSFGKV-KLAYHTTTGQKVALKIINKKVLAKS 94
Query: 81 DIACLKRVIVPDENGLNELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLME 140
D+ + E+ ++ LR P+I++ YD S+ EI++++E
Sbjct: 95 DMQ-------------GRIEREISYLRLLR-HPHIIKLYDVIKSKD-------EIIMVIE 133
Query: 141 LCPKKSLLDYMNNKLATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKD 200
+ L DY+ + K++E E + + +A+ H ++HRD+K EN+L+D+
Sbjct: 134 YAGNE-LFDYIVQR--DKMSEQEARRFFQQIISAVEYCHR--HKIVHRDLKPENLLLDEH 188
Query: 201 DNFKLCDFGSTSMCFPIVSTHQDIAVLTNNIYVHT---TPQYRSPEMIDLYRCLPINEKS 257
N K+ DFG ++ ++T+ ++ T +P Y +PE+I L +
Sbjct: 189 LNVKIADFGLSN-------------IMTDGNFLKTSCGSPNYAAPEVIS--GKLYAGPEV 233
Query: 258 DIWALGIFLYKLLFYTTPFE---LTGQFA-ILHSKYEIPQNGYSSKLINLIIIMLAENPS 313
D+W+ G+ LY +L PF+ + F I + Y +P+ S LI ML NP
Sbjct: 234 DVWSCGVILYVMLCRRLPFDDESIPVLFKNISNGVYTLPK-FLSPGAAGLIKRMLIVNPL 292
Query: 314 LRPNIYQVMHHVCSILKCDVP 334
R +I+++M K D+P
Sbjct: 293 NRISIHEIMQD--DWFKVDLP 311
>At5g49470 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 730
Score = 76.6 bits (187), Expect = 1e-13
Identities = 55/213 (25%), Positives = 103/213 (47%), Gaps = 37/213 (17%)
Query: 93 ENGLNELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMN 152
E + R EV MK+LR PN++ + + S + ++ E P+ SL +
Sbjct: 527 EEIITSFRQEVSLMKRLR-HPNVLLFMGAVTSPQ-------RLCIVTEFLPRGSLFRLLQ 578
Query: 153 NKLATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTS 212
+KL + + D++ + +H+ P+IHRD+K N+LVDK+ K+ DFG
Sbjct: 579 RN-TSKLDWRRRIHMASDIARGMNYLHHCTPPIIHRDLKSSNLLVDKNWTVKVADFG--- 634
Query: 213 MCFPIVSTHQDIAVLTNNIYVHT-----TPQYRSPEMIDLYRCLPINEKSDIWALGIFLY 267
++ + + Y+ T TPQ+ +PE++ R +EKSD+++ G+ L+
Sbjct: 635 -----------LSRIKHETYLTTKTGRGTPQWMAPEVL---RNEAADEKSDVYSFGVILW 680
Query: 268 KLLFYTTPFE------LTGQFAILHSKYEIPQN 294
+L+ P+E + G ++ + E+P+N
Sbjct: 681 ELVTEKIPWESLNAMQVIGAVGFMNQRLEVPKN 713
>At3g19300 [T] KOG1187 Serine/threonine protein kinase
Length = 663
Score = 76.6 bits (187), Expect = 1e-13
Identities = 64/235 (27%), Positives = 102/235 (43%), Gaps = 55/235 (23%)
Query: 48 LAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNELRNEVETMK 107
+ GGF +YK +F G +A +K++ E +E E+E +
Sbjct: 332 IGRGGFGTVYKAEFSN----------------GLVAAVKKMNKSSEQAEDEFCREIELLA 375
Query: 108 QLRGSPNIVQYYDSNASRHPDGSPGF-----EILLLMELCPKKSLLDYMNNKLATKLTEA 162
+L RH GF E L+ E SL D++++ + L+
Sbjct: 376 RLH-------------HRHLVALKGFCNKKNERFLVYEYMENGSLKDHLHSTEKSPLSWE 422
Query: 163 EILKIMYDVSNAIAQMH-YLPTPLIHRDIKIENVLVDKDDNFKLCDFG------STSMCF 215
+KI DV+NA+ +H Y PL HRDIK N+L+D+ KL DFG S+CF
Sbjct: 423 SRMKIAIDVANALEYLHFYCDPPLCHRDIKSSNILLDEHFVAKLADFGLAHASRDGSICF 482
Query: 216 PIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLL 270
V+T + TP Y PE + + + EKSD+++ G+ L +++
Sbjct: 483 EPVNTD-----------IRGTPGYVDPEYVVTHE---LTEKSDVYSYGVVLLEII 523
>Hs4507277_1 [R] KOG0589 Serine/threonine protein kinase
Length = 292
Score = 76.6 bits (187), Expect = 1e-13
Identities = 60/225 (26%), Positives = 103/225 (45%), Gaps = 25/225 (11%)
Query: 102 EVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLTE 161
E + + QL+ PNIV Y +S +G G + ++M C L + + L E
Sbjct: 53 EAQLLSQLK-HPNIVTYKESW-----EGGDGL-LYIVMGFCEGGDLYRKLKEQKGQLLPE 105
Query: 162 AEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTH 221
++++ ++ A+ +H ++HRD+K +NV + + + K+ D G ++ H
Sbjct: 106 NQVVEWFVQIAMALQYLH--EKHILHRDLKTQNVFLTRTNIIKVGDLGIAR----VLENH 159
Query: 222 QDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTPFELTGQ 281
D+A TP Y SPE L+ P N KSD+WALG +Y++ F
Sbjct: 160 CDMASTLIG-----TPYYMSPE---LFSNKPYNYKSDVWALGCCVYEMATLKHAFNAKDM 211
Query: 282 ----FAILHSKYEIPQNGYSSKLINLIIIMLAENPSLRPNIYQVM 322
+ I+ K YS +L LI ML++ P RP++ ++
Sbjct: 212 NSLVYRIIEGKLPAMPRDYSPELAELIRTMLSKRPEERPSVRSIL 256
>At5g28290 [R] KOG0589 Serine/threonine protein kinase
Length = 568
Score = 76.3 bits (186), Expect = 2e-13
Identities = 68/281 (24%), Positives = 126/281 (44%), Gaps = 43/281 (15%)
Query: 43 EILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNE--LR 100
E+LE + +G F + V+ + KL LK++ + + G
Sbjct: 5 EVLEQIGKGSFGSALLVRHKH---------EKKLY------VLKKIRLARQTGRTRRSAH 49
Query: 101 NEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLT 160
E+E + ++R +P IV+Y DS + G + +++ C + + + + +
Sbjct: 50 QEMELISKIR-NPFIVEYKDSWVEK------GCYVCIVIGYCKGGDMAEAIKKANGVEFS 102
Query: 161 EAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVST 220
E ++ K + + A+ +H + ++HRD+K N+ + KD + +L DFG + T
Sbjct: 103 EEKLCKWLVQLLMALEYLH--ASHILHRDVKCSNIFLTKDQDIRLGDFGLAK-----ILT 155
Query: 221 HQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYT---TPFE 277
D+A V TP Y PE++ +P KSDIW+LG +Y++ F+
Sbjct: 156 SDDLA-----SSVVGTPSYMCPELL---ADIPYGSKSDIWSLGCCMYEMTALKPAFKAFD 207
Query: 278 LTGQFAILHSKYEIPQNG-YSSKLINLIIIMLAENPSLRPN 317
+ G ++ P YS+ +L+ ML +NP LRP+
Sbjct: 208 MQGLINRINRSIVAPLPAQYSTAFRSLVKSMLRKNPELRPS 248
>At4g24480 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 963
Score = 76.3 bits (186), Expect = 2e-13
Identities = 66/248 (26%), Positives = 117/248 (46%), Gaps = 35/248 (14%)
Query: 100 RNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKL 159
+ V MK++R PN+V + + R + ++ E P+ SL ++ + +L
Sbjct: 717 KQAVAIMKRVR-HPNVVLFMGAVTERP-------RLSIITEYLPRGSLFRLIHRPASGEL 768
Query: 160 TEAEI-LKIMYDVSNAIAQ-------MHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGST 211
+ L++ DV AI +H L P++H D+K N+LVDK+ K+CDFG +
Sbjct: 769 LDQRRRLRMALDVVCAIPHYAKGLNYLHCLNPPVVHWDLKSPNLLVDKNWTVKVCDFGLS 828
Query: 212 SMCFPIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLF 271
+ +A TP++ +PE + R P NEKSD+++ G+ L++L+
Sbjct: 829 RFKANTFIPSKSVA---------GTPEWMAPEFL---RGEPTNEKSDVYSFGVVLWELIT 876
Query: 272 YTTPF------ELTGQFAILHSKYEIPQNGYSSKLINLIIIMLAENPSLRPNIYQVMHHV 325
P+ ++ G A + + IP N S L++L+ A+ PS RP ++ +
Sbjct: 877 LQQPWNGLSPAQVVGAVAFQNRRLIIPPN-TSPVLVSLMEACWADEPSQRPAFGSIVDTL 935
Query: 326 CSILKCDV 333
+LK V
Sbjct: 936 KKLLKSPV 943
>SPAC2C4.14c [T] KOG0201 Serine/threonine protein kinase
Length = 312
Score = 75.9 bits (185), Expect = 2e-13
Identities = 80/327 (24%), Positives = 137/327 (41%), Gaps = 46/327 (14%)
Query: 40 HRCEILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNEL 99
H+ L+ + +G F ++++ + +E + + LK D+ K + + L
Sbjct: 4 HQYRDLQLIGQGSFGSVFRAQDVESSKIV-------ALKVVDLDATK-------DQIETL 49
Query: 100 RNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKL 159
E+ + L S +I +YY S GF + + ME C S LD + KL+
Sbjct: 50 TQEINFLIDLN-SVHITKYYASFVD-------GFRLWITMEYCDGGSCLDLL--KLSGTF 99
Query: 160 TEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVS 219
+E I ++M V A+ +H +HRDIK N+L KD KL DFG + +
Sbjct: 100 SERVIAEVMRQVLEALVYLH--GQGKMHRDIKAANILTMKDGLVKLADFGVSGQLESLRD 157
Query: 220 THQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTPFELT 279
+ D TP + +PE++ + N K+DIW+LGI Y+L P+
Sbjct: 158 KNDDFV---------GTPFWMAPEVV---KQTGYNYKADIWSLGITAYELATGEPPYSGI 205
Query: 280 GQFAIL-----HSKYEIPQNGYSSKLINLIIIMLAENPSLRPNIYQVMHHVCSILKCDVP 334
+L HS + ++ +S + + L +NP R + H +K P
Sbjct: 206 HPMKVLLLIPKHSPPSLERSKFSRAFCDFVSNCLKKNPKDRATAEYLSKH--KFIKKYCP 263
Query: 335 FTDKYELGPYDFAKYSQYHLKLQQIQY 361
T E+ +AK+ + L + Y
Sbjct: 264 NTSVKEV-VASYAKWKESELLPEATPY 289
>Hs6005810 [T] KOG0576 Mitogen-activated protein kinase kinase kinase kinase
(MAP4K) germinal center kinase family
Length = 833
Score = 75.9 bits (185), Expect = 2e-13
Identities = 72/275 (26%), Positives = 123/275 (44%), Gaps = 34/275 (12%)
Query: 63 ELTNEMDAGIDSKLLKA-----GDIACLKRVIVPDENGLNELRNEVETMKQLRGSPNIVQ 117
+L + G ++ KA GD+ LK V + ++ ++ L+ E+ +K R + NIV
Sbjct: 18 DLLQRLGGGTYGEVFKARDKVSGDLVALKMVKMEPDDDVSTLQKEILILKTCRHA-NIVA 76
Query: 118 YYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLTEAEILKIMYDVSNAIAQ 177
Y+ S ++ + ME C SL D ++ L+E +I + +V +A
Sbjct: 77 YHGSYLWLQ-------KLWICMEFCGAGSLQDIY--QVTGSLSELQISYVCREVLQGLAY 127
Query: 178 MHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTHQDIAVLTNNIYVHTTP 237
+H IHRDIK N+L++ +L DFG ++ Q A L + TP
Sbjct: 128 LH--SQKKIHRDIKGANILINDAGEVRLADFGISA---------QIGATLARRLSFIGTP 176
Query: 238 QYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTPF----ELTGQFAILHSKYEIP- 292
+ +PE+ + NE DIW+LGI +L P L F + S Y+ P
Sbjct: 177 YWMAPEVAAVALKGGYNELCDIWSLGITAIELAELQPPLFDVHPLRVLFLMTKSGYQPPR 236
Query: 293 ---QNGYSSKLINLIIIMLAENPSLRPNIYQVMHH 324
+ +S+ N I + L ++P RP+ +++ H
Sbjct: 237 LKEKGKWSAAFHNFIKVTLTKSPKKRPSATKMLSH 271
>At5g11850 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 886
Score = 75.9 bits (185), Expect = 2e-13
Identities = 60/223 (26%), Positives = 111/223 (48%), Gaps = 29/223 (13%)
Query: 80 GDIACLKRVIVPDENG--LNELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILL 137
G +K+ + D +G L + ++E+E M +LR PN+V + + +R P+ S +
Sbjct: 670 GTEVAVKKFLDQDFSGDALTQFKSEIEIMLRLR-HPNVVLFMGA-VTRPPNFS------I 721
Query: 138 LMELCPKKSLLDYMNNKLATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLV 197
L E P+ SL ++ +L E +++ DV+ + +H ++HRD+K N+LV
Sbjct: 722 LTEFLPRGSLYRLLHRP-NHQLDEKRRMRMALDVAKGMNYLHTSHPTVVHRDLKSPNLLV 780
Query: 198 DKDDNFKLCDFGSTSMCFPIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKS 257
DK+ K+CDFG + M + + A TP++ +PE++ R P NEK
Sbjct: 781 DKNWVVKVCDFGLSRMKHHTYLSSKSTA---------GTPEWMAPEVL---RNEPANEKC 828
Query: 258 DIWALGIFLYKLLFYTTPF------ELTGQFAILHSKYEIPQN 294
D+++ G+ L++L P+ ++ G + + EIP +
Sbjct: 829 DVYSFGVILWELATSRVPWKGLNPMQVVGAVGFQNRRLEIPDD 871
>At3g04810 [R] KOG0589 Serine/threonine protein kinase
Length = 606
Score = 75.9 bits (185), Expect = 2e-13
Identities = 68/286 (23%), Positives = 127/286 (43%), Gaps = 43/286 (15%)
Query: 43 EILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNE--LR 100
E+LE + +G F + V+ + KL LK++ + + G
Sbjct: 5 EVLEQIGKGSFGSALLVRHKH---------EKKLY------VLKKIRLARQTGRTRRSAH 49
Query: 101 NEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLT 160
E+E + ++ +P IV+Y DS + G + +++ C + + + T
Sbjct: 50 QEMELISKIH-NPFIVEYKDSWVEK------GCYVCIIIGYCKGGDMAEAIKKTNGVHFT 102
Query: 161 EAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVST 220
E ++ K + + A+ +H ++HRD+K N+ + KD + +L DFG V T
Sbjct: 103 EEKLCKWLVQILLALEYLH--ANHILHRDVKCSNIFLTKDQDIRLGDFGLAK-----VLT 155
Query: 221 HQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTPFELTG 280
D+A V TP Y PE++ +P KSDIW+LG +Y++ F+
Sbjct: 156 SDDLA-----SSVVGTPSYMCPELL---ADIPYGSKSDIWSLGCCMYEMTAMKPAFKAFD 207
Query: 281 QFAILH--SKYEIP--QNGYSSKLINLIIIMLAENPSLRPNIYQVM 322
+++ ++ +P YS+ L+ ML +NP LRP+ +++
Sbjct: 208 MQGLINRINRSIVPPLPAQYSAAFRGLVKSMLRKNPELRPSAAELL 253
>Hs18552621 [R] KOG0597 Serine-threonine protein kinase FUSED
Length = 1315
Score = 75.1 bits (183), Expect = 4e-13
Identities = 72/286 (25%), Positives = 129/286 (44%), Gaps = 45/286 (15%)
Query: 44 ILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRV--IVPDENGLNELRN 101
+LE + EG F +YK + + + LK + + E L L+
Sbjct: 6 VLEMIGEGSFGRVYK---------------GRRKYSAQVVALKFIPKLGRSEKELRNLQR 50
Query: 102 EVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLTE 161
E+E M+ LR PNIV DS + E++++ + + L + + KL E
Sbjct: 51 EIEIMRGLR-HPNIVHMLDSFETDK-------EVVVVTDYA-EGELFQILEDD--GKLPE 99
Query: 162 AEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTH 221
++ I + +A+ +H ++HRD+K +N+L+ K KLCDFG +
Sbjct: 100 DQVQAIAAQLVSALYYLH--SHRILHRDMKPQNILLAKGGGIKLCDFGFAR------AMS 151
Query: 222 QDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTPFELTGQ 281
+ VLT+ + TP Y SPE+++ P + +D+W++G LY+L T PF T
Sbjct: 152 TNTMVLTS---IKGTPLYMSPELVEE---RPYDHTADLWSVGCILYELAVGTPPFYATSI 205
Query: 282 FAILHSKYEIP---QNGYSSKLINLIIIMLAENPSLRPNIYQVMHH 324
F ++ + P + S N + +L ++P R + +++H
Sbjct: 206 FQLVSLILKDPVRWPSTISPCFKNFLQGLLTKDPRQRLSWPDLLYH 251
>CE27768 [R] KOG0586 Serine/threonine protein kinase
Length = 1096
Score = 75.1 bits (183), Expect = 4e-13
Identities = 82/324 (25%), Positives = 141/324 (43%), Gaps = 50/324 (15%)
Query: 6 TISRPNSVAHTAATSAMIPNSHLLSPNTQVVVGTHRCEILEHLAEGGFANIYKVKFLELT 65
T +S A + S M S + V VG ++ +L+ + +G FA + K +
Sbjct: 88 TSGSSSSHARSTGQSGMSSRSAARRNDQDVHVGKYK--LLKTIGKGNFAKVKLAKHVITG 145
Query: 66 NEMDAGIDSKLLKAGDIACLKRVIVPDENGLNELRNEVETMKQLRGSPNIVQYYDSNASR 125
+E+ I K + + L +L EV+ MKQL PNIV+ Y +
Sbjct: 146 HEVAIKIIDKTAL-------------NPSSLQKLFREVKIMKQL-DHPNIVKLYQVMETE 191
Query: 126 HPDGSPGFEILLLMELCPKKSLLDYM--NNKLATKLTEAEILKIMYDVSNAIAQMHYLPT 183
+ L++E + DY+ + ++ K A+ +I+ +A+ +H
Sbjct: 192 QT-------LYLVLEYASGGEVFDYLVAHGRMKEKEARAKFRQIV----SAVQYLH--SK 238
Query: 184 PLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTHQDIAVLTNNIYVHT-TPQYRSP 242
+IHRD+K EN+L+D+D N K+ DFG + L N + +P Y +P
Sbjct: 239 NIIHRDLKAENLLLDQDMNIKIADFG-----------FSNTFSLGNKLDTFCGSPPYAAP 287
Query: 243 EMIDLYRCLPINEKSDIWALGIFLYKLLFYTTPFELTG----QFAILHSKYEIPQNGYSS 298
E+ + + D+W+LG+ LY L+ + PF+ + +L KY IP S+
Sbjct: 288 ELFSGKKY--DGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFY-MST 344
Query: 299 KLINLIIIMLAENPSLRPNIYQVM 322
NL+ L NP R ++ +M
Sbjct: 345 DCENLLKKFLVINPQRRSSLDNIM 368
>CE23838 [R] KOG0586 Serine/threonine protein kinase
Length = 1192
Score = 75.1 bits (183), Expect = 4e-13
Identities = 82/324 (25%), Positives = 141/324 (43%), Gaps = 50/324 (15%)
Query: 6 TISRPNSVAHTAATSAMIPNSHLLSPNTQVVVGTHRCEILEHLAEGGFANIYKVKFLELT 65
T +S A + S M S + V VG ++ +L+ + +G FA + K +
Sbjct: 136 TSGSSSSHARSTGQSGMSSRSAARRNDQDVHVGKYK--LLKTIGKGNFAKVKLAKHVITG 193
Query: 66 NEMDAGIDSKLLKAGDIACLKRVIVPDENGLNELRNEVETMKQLRGSPNIVQYYDSNASR 125
+E+ I K + + L +L EV+ MKQL PNIV+ Y +
Sbjct: 194 HEVAIKIIDKTAL-------------NPSSLQKLFREVKIMKQL-DHPNIVKLYQVMETE 239
Query: 126 HPDGSPGFEILLLMELCPKKSLLDYM--NNKLATKLTEAEILKIMYDVSNAIAQMHYLPT 183
+ L++E + DY+ + ++ K A+ +I+ +A+ +H
Sbjct: 240 QT-------LYLVLEYASGGEVFDYLVAHGRMKEKEARAKFRQIV----SAVQYLH--SK 286
Query: 184 PLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTHQDIAVLTNNIYVHT-TPQYRSP 242
+IHRD+K EN+L+D+D N K+ DFG + L N + +P Y +P
Sbjct: 287 NIIHRDLKAENLLLDQDMNIKIADFG-----------FSNTFSLGNKLDTFCGSPPYAAP 335
Query: 243 EMIDLYRCLPINEKSDIWALGIFLYKLLFYTTPFELTG----QFAILHSKYEIPQNGYSS 298
E+ + + D+W+LG+ LY L+ + PF+ + +L KY IP S+
Sbjct: 336 ELFSGKKY--DGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFY-MST 392
Query: 299 KLINLIIIMLAENPSLRPNIYQVM 322
NL+ L NP R ++ +M
Sbjct: 393 DCENLLKKFLVINPQRRSSLDNIM 416
>At3g06620 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 773
Score = 75.1 bits (183), Expect = 4e-13
Identities = 60/233 (25%), Positives = 110/233 (46%), Gaps = 28/233 (12%)
Query: 96 LNELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKL 155
+ + EV MK+LR PN++ + + S + ++ E P+ SL + K
Sbjct: 533 IESFKQEVLLMKRLR-HPNVLLFMGAVTSPQ-------RLCIVSEFLPRGSLFRLLQ-KS 583
Query: 156 ATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCF 215
+KL + + D++ + +H+ P+IHRD+K N+LVDK+ K+ DFG + +
Sbjct: 584 TSKLDWRRRIHMALDIARGMNYLHHCSPPIIHRDLKSSNLLVDKNWTVKVADFGLSRIKH 643
Query: 216 PIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTP 275
T + TPQ+ +PE++ R +EKSDI++ G+ L++L P
Sbjct: 644 ETYLTSKS---------GKGTPQWMAPEVL---RNESADEKSDIYSFGVVLWELATEKIP 691
Query: 276 FE------LTGQFAILHSKYEIPQNGYSSKLINLIIIMLAENPSLRPNIYQVM 322
+E + G + + EIP++ + I+L+ + LRP ++M
Sbjct: 692 WETLNSMQVIGAVGFMDQRLEIPKD-IDPRWISLMESCWHSDTKLRPTFQELM 743
>7297240_1 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 326
Score = 75.1 bits (183), Expect = 4e-13
Identities = 75/304 (24%), Positives = 135/304 (43%), Gaps = 39/304 (12%)
Query: 31 PNTQVVVGTHRCEILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIV 90
P Q+ T + EI E +A+G A +++ K EL N+ I LK
Sbjct: 5 PYAQLPDPTDKFEIYEEIAQGVNAKVFRAK--ELDNDR-------------IVALKIQHY 49
Query: 91 PDENGLNELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDY 150
+E+ ++ + E T++ PN+ ++Y P+G EI +ME C + +D
Sbjct: 50 DEEHQVS-IEEEYRTLRDYCDHPNLPEFYGVYKLSKPNGPD--EIWFVMEYCAGGTAVDM 106
Query: 151 MNN--KLATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDF 208
+N KL ++ E I I+ + A +++ ++HRDI+ +N+L+ K+ KLCDF
Sbjct: 107 VNKLLKLDRRMREEHIAYIIRETCRAAIELNR--NHVLHRDIRGDNILLTKNGRVKLCDF 164
Query: 209 GSTSMCFPIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLY--RCLPINEKSDIWALGIFL 266
G + Q + L +P + +PE++ R I ++D+WALGI
Sbjct: 165 G---------LSRQVDSTLGKRGTCIGSPCWMAPEVVSAMESREPDITVRADVWALGITT 215
Query: 267 YKLLFYTTPF----ELTGQFAILHSKYE--IPQNGYSSKLINLIIIMLAENPSLRPNIYQ 320
+L PF F I+ + + +S ++ + I L +N RP + +
Sbjct: 216 IELADGKPPFADMHPTRAMFQIIRNPPPTLMRPTNWSQQINDFISESLEKNAENRPMMVE 275
Query: 321 VMHH 324
++ H
Sbjct: 276 MVEH 279
>At3g23000 [T] KOG0583 Serine/threonine protein kinase
Length = 429
Score = 74.7 bits (182), Expect = 5e-13
Identities = 77/288 (26%), Positives = 134/288 (45%), Gaps = 46/288 (15%)
Query: 43 EILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLN-ELRN 101
E+ L G FA ++ + I+S L A I K+ I E+G+ +
Sbjct: 26 ELGRRLGSGSFAKVHLAR----------SIESDELVAVKIIEKKKTI---ESGMEPRIIR 72
Query: 102 EVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLTE 161
E++ M++LR PNI++ ++ A++ +I L+MEL L + + +L E
Sbjct: 73 EIDAMRRLRHHPNILKIHEVMATKS-------KIYLVMELASGGELFSKVLRR--GRLPE 123
Query: 162 AEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTH 221
+ + +++A+ H + HRD+K +N+L+D+ N K+ DFG +++ H
Sbjct: 124 STARRYFQQLASALRFSHQ--DGVAHRDVKPQNLLLDEQGNLKVSDFGLSAL-----PEH 176
Query: 222 QDIAVLTNNIYVHT---TPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTPFE- 277
N +HT TP Y +PE+I R K+D W+ G+ L+ LL PF+
Sbjct: 177 ------LQNGLLHTACGTPAYTAPEVIS--RRGYDGAKADAWSCGVILFVLLVGDVPFDD 228
Query: 278 --LTGQFAILHSK-YEIPQNGYSSKLINLIIIMLAENPSLRPNIYQVM 322
+ + +H + Y P + S + ++I ML NP R +I VM
Sbjct: 229 SNIAAMYRKIHRRDYRFP-SWISKQAKSIIYQMLDPNPVTRMSIETVM 275
>At1g67890 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 738
Score = 74.7 bits (182), Expect = 5e-13
Identities = 55/208 (26%), Positives = 103/208 (49%), Gaps = 28/208 (13%)
Query: 93 ENGLNELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMN 152
E + + EV MK+LR PN++ + + AS + ++ E P+ SL +
Sbjct: 523 EEIITSFKQEVSLMKRLR-HPNVLLFMGAVASPQ-------RLCIVTEFLPRGSLFRLLQ 574
Query: 153 NKLATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTS 212
+KL + + D++ + +H+ P+IHRD+K N+LVD++ K+ DFG
Sbjct: 575 RN-KSKLDLRRRIHMASDIARGMNYLHHCSPPIIHRDLKSSNLLVDRNWTVKVADFG--- 630
Query: 213 MCFPIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFY 272
+S + LT N TPQ+ +PE++ R +EKSD+++ G+ L++L+
Sbjct: 631 -----LSRIKHETYLTTN--GRGTPQWMAPEVL---RNEAADEKSDVYSFGVVLWELVTE 680
Query: 273 TTPFE------LTGQFAILHSKYEIPQN 294
P+E + G ++ + E+P++
Sbjct: 681 KIPWENLNAMQVIGAVGFMNQRLEVPKD 708
>Hs4505785 [G] KOG0599 Phosphorylase kinase gamma subunit
Length = 406
Score = 74.3 bits (181), Expect = 7e-13
Identities = 64/235 (27%), Positives = 108/235 (45%), Gaps = 31/235 (13%)
Query: 100 RNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKL 159
R E ++Q+ G P+I+ DS S + L+ +L K L DY+ K+A L
Sbjct: 75 RRETHILRQVAGHPHIITLIDSYESSS-------FMFLVFDLMRKGELFDYLTEKVA--L 125
Query: 160 TEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVS 219
+E E IM + A++ +H ++HRD+K EN+L+D + +L DFG + P
Sbjct: 126 SEKETRSIMRSLLEAVSFLH--ANNIVHRDLKPENILLDDNMQIRLSDFGFSCHLEPGEK 183
Query: 220 THQDIAVLTNNIYVHTTPQYRSPEMI--DLYRCLP-INEKSDIWALGIFLYKLLFYTTPF 276
+ + TP Y +PE++ + P ++ D+WA G+ L+ LL + PF
Sbjct: 184 LRE----------LCGTPGYLAPEILKCSMDETHPGYGKEVDLWACGVILFTLLAGSPPF 233
Query: 277 ELTGQF----AILHSKYEIPQ---NGYSSKLINLIIIMLAENPSLRPNIYQVMHH 324
Q I+ +Y+ + SS + +LI +L +P R Q + H
Sbjct: 234 WHRRQILMLRMIMEGQYQFSSPEWDDRSSTVKDLISRLLQVDPEARLTAEQALQH 288
>At3g06640 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 763
Score = 74.3 bits (181), Expect = 7e-13
Identities = 62/239 (25%), Positives = 112/239 (45%), Gaps = 28/239 (11%)
Query: 93 ENGLNELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMN 152
E + R EV M++LR PN++ + A P G + ++ E P+ SL +
Sbjct: 482 EEVIQSFRQEVSLMQRLR-HPNVLLFM--GAVTLPQG-----LCIVSEFLPRGSLFRLLQ 533
Query: 153 NKLATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTS 212
++ KL + + D++ + +H P+IHRD+K N+LVDK+ K+ DFG +
Sbjct: 534 RNMS-KLDWRRRINMALDIARGMNYLHRCSPPIIHRDLKSSNLLVDKNLTVKVADFGLSR 592
Query: 213 MCFPIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFY 272
+ H + + PQ+ +PE++ R +EKSDI++ G+ L++L
Sbjct: 593 -----IKHHTYLTSKSGK----GMPQWMAPEVL---RNESADEKSDIYSFGVVLWELATE 640
Query: 273 TTPFE------LTGQFAILHSKYEIPQNGYSSKLINLIIIMLAENPSLRPNIYQVMHHV 325
P+E + G ++ + EIP++ I+LI + LRP ++M +
Sbjct: 641 KIPWENLNSMQVIGAVGFMNQRLEIPKD-IDPDWISLIESCWHRDAKLRPTFQELMERL 698
>At3g25490 [T] KOG1187 Serine/threonine protein kinase
Length = 433
Score = 73.9 bits (180), Expect = 9e-13
Identities = 79/285 (27%), Positives = 130/285 (44%), Gaps = 49/285 (17%)
Query: 44 ILEHLAEGGFANI-YKVKFLELTNEMDAGID-SKLLKAG-------------DIACLKRV 88
++E L+ G +NI +K+ E E G D S++L G I +K+
Sbjct: 79 LIERLSGAGSSNIDFKIFTEEDMKEATNGYDVSRILGQGGQWTVYKGILPDNSIVAIKKT 138
Query: 89 IVPDENGLNELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLL 148
+ D N + + NEV + Q+ N+V+ LL+ E SL
Sbjct: 139 RLGDNNQVEQFINEVLVLSQINHR-NVVKLLGCCLETEVP-------LLVYEFITGGSLF 190
Query: 149 DYMNNKL-ATKLTEAEILKIMYDVSNAIAQMHY-LPTPLIHRDIKIENVLVDKDDNFKLC 206
D+++ + + LT L+I +V+ AIA +H P+IHRDIK EN+L+D++ K+
Sbjct: 191 DHLHGSMFVSSLTWEHRLEIAIEVAGAIAYLHSGASIPIIHRDIKTENILLDENLTAKVA 250
Query: 207 DFGSTSMCFPIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFL 266
DFG++ + D LT V T Y PE Y +NEKSD+++ G+ L
Sbjct: 251 DFGASKL------KPMDKEQLTT--MVQGTLGYLDPE---YYTTWLLNEKSDVYSFGVVL 299
Query: 267 YKLLFYTTPFELTGQFAILHSKYEIPQNGYSSKLINLIIIMLAEN 311
+L ++GQ A+ +E P+ S L++ ++ EN
Sbjct: 300 MEL--------ISGQKALC---FERPET--SKHLVSYFVLATKEN 331
>At2g39110 [T] KOG1187 Serine/threonine protein kinase
Length = 419
Score = 73.9 bits (180), Expect = 9e-13
Identities = 69/232 (29%), Positives = 108/232 (45%), Gaps = 27/232 (11%)
Query: 48 LAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNELRNEVETMK 107
+ EGGF +++ + N D+ K DIA +K++ G E EV +
Sbjct: 81 IGEGGFGGVFRGV---IQNPQDSR------KKIDIA-VKQLSRRGLQGHKEWVTEVNVLG 130
Query: 108 QLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNK-LATKLTEAEILK 166
+ PN+V+ A D G + LL+ E +S+ D+++N+ + T L + LK
Sbjct: 131 VVE-HPNLVKLIGYCAE---DDERGIQRLLVYEYVQNRSVQDHLSNRFIVTPLPWSTRLK 186
Query: 167 IMYDVSNAIAQMHY-LPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTHQDIA 225
I D + +A +H + +I RD K N+L+D++ N KL DFG M TH
Sbjct: 187 IAQDTARGLAYLHQGMEFQIIFRDFKSSNILLDENWNAKLSDFGLARMGPSDGITHVSTV 246
Query: 226 VLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTPFE 277
V T Y +PE I + KSD+W+ GIFLY+L+ PF+
Sbjct: 247 VGTIG--------YAAPEYIQTGH---LTAKSDVWSYGIFLYELITGRRPFD 287
>7297080 [T] KOG0583 Serine/threonine protein kinase
Length = 329
Score = 73.9 bits (180), Expect = 9e-13
Identities = 71/277 (25%), Positives = 119/277 (42%), Gaps = 39/277 (14%)
Query: 52 GFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNELRNEVETMKQLRG 111
G N KVK G + K + + +V P E L E+E +K L
Sbjct: 75 GTGNYAKVKI---------GFSEEYGKRVAVKIISKVKAPSEYTQKFLPREIEAVKGLHH 125
Query: 112 SPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLTEAEILKIMYDV 171
N++ +Y S + H + L+M+L +LLDY+ + L E + + +
Sbjct: 126 E-NLITFYQSIETSH-------RVYLIMQLAENGTLLDYVRERKF--LDEPQSRTLFKQL 175
Query: 172 SNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTHQDIAVLTNNI 231
+A+ +H ++HRDIK EN+L+D++ N KL DFG +D N +
Sbjct: 176 VSAVEYIH--SKGVVHRDIKCENLLLDENWNLKLIDFG---------FARKDTRTSDNQV 224
Query: 232 YVHTT----PQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTPFELTGQFAIL-- 285
+ T Y SPE++ P SDIWA G+ Y ++F P++ + +L
Sbjct: 225 ILSKTFCGSYAYASPEILKGVAYDPF--MSDIWACGVVCYAMVFGRLPYDGSNVHILLKR 282
Query: 286 -HSKYEIPQNGYSSKLINLIIIMLAENPSLRPNIYQV 321
+ P++ +S +I+ + +R NI QV
Sbjct: 283 INQSLVFPKSPSASSECKHMIMHILAPVKIRYNIPQV 319
>At1g69220 [T] KOG0576 Mitogen-activated protein kinase kinase kinase kinase
(MAP4K) germinal center kinase family
Length = 836
Score = 73.6 bits (179), Expect = 1e-12
Identities = 72/293 (24%), Positives = 123/293 (41%), Gaps = 45/293 (15%)
Query: 39 THRCEILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPD-ENGLN 97
T + E L L +G + ++YK + L K +I +K + + + E G
Sbjct: 246 TTKYEFLNELGKGSYGSVYKARDL---------------KTSEIVAVKVISLTEGEEGYE 290
Query: 98 ELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLAT 157
E+R E+E ++Q PN+V+Y S + ++ME C S+ D MN
Sbjct: 291 EIRGEIEMLQQCN-HPNVVRYLGSYQGED-------YLWIVMEYCGGGSVADLMN-VTEE 341
Query: 158 KLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPI 217
L E +I I + +A +H + +HRDIK N+L+ + KL DFG
Sbjct: 342 ALEEYQIAYICREALKGLAYLHSIYK--VHRDIKGGNILLTEQGEVKLGDFG-------- 391
Query: 218 VSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTPFE 277
V+ + N ++ TP + +PE+I R + K D+WALG+ ++ P
Sbjct: 392 VAAQLTRTMSKRNTFI-GTPHWMAPEVIQENR---YDGKVDVWALGVSAIEMAEGLPPRS 447
Query: 278 LTGQFAILHSKYEIP------QNGYSSKLINLIIIMLAENPSLRPNIYQVMHH 324
+L P + +S + + L + P LRP +++ H
Sbjct: 448 SVHPMRVLFMISIEPAPMLEDKEKWSLVFHDFVAKCLTKEPRLRPTAAEMLKH 500
>CE28273 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1096
Score = 73.2 bits (178), Expect = 2e-12
Identities = 60/225 (26%), Positives = 104/225 (45%), Gaps = 30/225 (13%)
Query: 43 EILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNELRNE 102
E++E + G + +YK + +K +A +K + + +E+ +E++ E
Sbjct: 22 ELIEVVGNGTYGQVYK---------------GRHVKTAQLAAIKIMNI-NEDEEDEIKLE 65
Query: 103 VETMKQLRGSPNIVQYYDSNASRHPDGSPGFEIL-LLMELCPKKSLLDYMNNKLATKLTE 161
+ +K+ N+ YY + + P + + L L+ME C S+ D + N L E
Sbjct: 66 INMLKKHSHHRNVATYYGAFIKKLPSSTGKHDQLWLVMEFCGSGSITDLVKNTKGGSLKE 125
Query: 162 AEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTH 221
I I ++ + +H + +IHRDIK +NVL+ KL DFG VS
Sbjct: 126 EWIAYICREILRGLYHLHQ--SKVIHRDIKGQNVLLTDSAEVKLVDFG--------VSAQ 175
Query: 222 QDIAVLTNNIYVHTTPQYRSPEMI--DLYRCLPINEKSDIWALGI 264
D V N ++ TP + +PE+I D + +SD+W+LGI
Sbjct: 176 LDKTVGRRNTFI-GTPYWMAPEVIACDESPEATYDSRSDLWSLGI 219
>CE25673 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1082
Score = 73.2 bits (178), Expect = 2e-12
Identities = 60/225 (26%), Positives = 104/225 (45%), Gaps = 30/225 (13%)
Query: 43 EILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNELRNE 102
E++E + G + +YK + +K +A +K + + +E+ +E++ E
Sbjct: 22 ELIEVVGNGTYGQVYK---------------GRHVKTAQLAAIKIMNI-NEDEEDEIKLE 65
Query: 103 VETMKQLRGSPNIVQYYDSNASRHPDGSPGFEIL-LLMELCPKKSLLDYMNNKLATKLTE 161
+ +K+ N+ YY + + P + + L L+ME C S+ D + N L E
Sbjct: 66 INMLKKHSHHRNVATYYGAFIKKLPSSTGKHDQLWLVMEFCGSGSITDLVKNTKGGSLKE 125
Query: 162 AEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTH 221
I I ++ + +H + +IHRDIK +NVL+ KL DFG VS
Sbjct: 126 EWIAYICREILRGLYHLHQ--SKVIHRDIKGQNVLLTDSAEVKLVDFG--------VSAQ 175
Query: 222 QDIAVLTNNIYVHTTPQYRSPEMI--DLYRCLPINEKSDIWALGI 264
D V N ++ TP + +PE+I D + +SD+W+LGI
Sbjct: 176 LDKTVGRRNTFI-GTPYWMAPEVIACDESPEATYDSRSDLWSLGI 219
>CE25672 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1087
Score = 73.2 bits (178), Expect = 2e-12
Identities = 60/225 (26%), Positives = 104/225 (45%), Gaps = 30/225 (13%)
Query: 43 EILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNELRNE 102
E++E + G + +YK + +K +A +K + + +E+ +E++ E
Sbjct: 22 ELIEVVGNGTYGQVYK---------------GRHVKTAQLAAIKIMNI-NEDEEDEIKLE 65
Query: 103 VETMKQLRGSPNIVQYYDSNASRHPDGSPGFEIL-LLMELCPKKSLLDYMNNKLATKLTE 161
+ +K+ N+ YY + + P + + L L+ME C S+ D + N L E
Sbjct: 66 INMLKKHSHHRNVATYYGAFIKKLPSSTGKHDQLWLVMEFCGSGSITDLVKNTKGGSLKE 125
Query: 162 AEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTH 221
I I ++ + +H + +IHRDIK +NVL+ KL DFG VS
Sbjct: 126 EWIAYICREILRGLYHLHQ--SKVIHRDIKGQNVLLTDSAEVKLVDFG--------VSAQ 175
Query: 222 QDIAVLTNNIYVHTTPQYRSPEMI--DLYRCLPINEKSDIWALGI 264
D V N ++ TP + +PE+I D + +SD+W+LGI
Sbjct: 176 LDKTVGRRNTFI-GTPYWMAPEVIACDESPEATYDSRSDLWSLGI 219
>At4g04700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 347
Score = 73.2 bits (178), Expect = 2e-12
Identities = 71/243 (29%), Positives = 113/243 (46%), Gaps = 35/243 (14%)
Query: 92 DENGLNELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYM 151
DE +++ E+ MKQL G PNIV++ NA D + ++ME C L D +
Sbjct: 66 DEECEEDVKREIRIMKQLSGEPNIVEF--KNAYEDKD-----SVHIVMEYCGGGELYDKI 118
Query: 152 --NNKLATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIEN-VLVDKDDN--FKLC 206
+ +E E I+ + N + HY+ ++HRD+K EN +L DDN K+
Sbjct: 119 LALYDVGKSYSEKEAAGIIRSIVNVVKNCHYM--GVMHRDLKPENFLLTSNDDNATVKVI 176
Query: 207 DFGSTSMCFPIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFL 266
DFG S+ +QD+A + Y +PE++ +++DIW+ GI L
Sbjct: 177 DFG-CSVFIEEGKVYQDLA---------GSDYYIAPEVLQ----GNYGKEADIWSAGIIL 222
Query: 267 YKLLFYTTPF------ELTGQFAILHSKY-EIPQNGYSSKLINLIIIMLAENPSLRPNIY 319
Y LL +PF ++ + L Y E P S+ I+L+ ML NP R +
Sbjct: 223 YILLCGKSPFVKEPEGQMFNEIKSLEIDYSEEPWPLRDSRAIHLVKRMLDRNPKERISAA 282
Query: 320 QVM 322
+V+
Sbjct: 283 EVL 285
>At4g00330 [T] KOG1187 Serine/threonine protein kinase
Length = 341
Score = 73.2 bits (178), Expect = 2e-12
Identities = 69/253 (27%), Positives = 115/253 (45%), Gaps = 53/253 (20%)
Query: 48 LAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRV---IVPDENGLN-ELRNEV 103
+ +GGF +YKVK L+ G +KR + D G + E +E+
Sbjct: 39 IGQGGFGTVYKVK----------------LRDGKTFAVKRAKKSMHDDRQGADAEFMSEI 82
Query: 104 ETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLAT------ 157
+T+ Q+ ++V+YY H D E +L++E +L D+++ + +
Sbjct: 83 QTLAQVTHL-SLVKYYGFVV--HND-----EKILVVEYVANGTLRDHLDCEYTSYYYLLF 134
Query: 158 ---KLTEAEILKIMYDVSNAIAQMH--------YLPTPLIHRDIKIENVLVDKDDNFKLC 206
L A L I DV++AI +H Y+ P+IHRDIK N+L+ ++ K+
Sbjct: 135 EGKTLDMATRLDIATDVAHAITYLHMYTRKSIVYIEPPIIHRDIKSSNILLTENYRAKVA 194
Query: 207 DFGSTSMCFPIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFL 266
DFG F ++ D + V T Y PE + Y+ + EKSD+++ G+ L
Sbjct: 195 DFG-----FARLAPDTDSGATHVSTQVKGTAGYLDPEYLTTYQ---LTEKSDVYSFGVLL 246
Query: 267 YKLLFYTTPFELT 279
+LL P EL+
Sbjct: 247 VELLTGRRPIELS 259
>SPAC9G1.02 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and related
serine/threonine protein kinases
Length = 1401
Score = 72.8 bits (177), Expect = 2e-12
Identities = 68/263 (25%), Positives = 123/263 (45%), Gaps = 31/263 (11%)
Query: 77 LKAGDIACLKRVIVPDE----NGLNELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPG 132
++ GD+ +K + + D + ++++ NE+ +++L PN+V YY R
Sbjct: 1057 METGDLLAVKEIKLQDSRTFRSTVDQIHNEMTVLERLN-HPNVVTYYGVEVHRE------ 1109
Query: 133 FEILLLMELCPKKSLLDYMNNKLATKLTEAEILKI-MYDVSNAIAQMHYLPTPLIHRDIK 191
++ + ME C SL D + + ++ + +LK+ + + +A +H ++HRDIK
Sbjct: 1110 -KVYIFMEFCQGGSLADLLAHG---RIEDENVLKVYVVQLLEGLAYIH--SQHILHRDIK 1163
Query: 192 IENVLVDKDDNFKLCDFGSTSMCFPIVS---THQDIAVLTNNIYVHTTPQYRSPEMIDLY 248
N+L+D K DFGS P ++DI ++ TP Y +PE+I L
Sbjct: 1164 PANILLDHRGMIKYSDFGSALYVSPPTDPEVRYEDIQPELQ--HLAGTPMYMAPEII-LG 1220
Query: 249 RCLPINEKSDIWALGIFLYKLLFYTTPF-ELTGQFAILH-----SKYEIPQNGYSSKLIN 302
DIW+LG + +++ +TP+ E+ ++AI++ IPQN S L
Sbjct: 1221 TKKGDFGAMDIWSLGCVILEMMTGSTPWSEMDNEWAIMYHVAAMHTPSIPQNEKISSLAR 1280
Query: 303 LIIIMLAE-NPSLRPNIYQVMHH 324
I E +P RP ++ H
Sbjct: 1281 DFIEQCFERDPEQRPRAVDLLTH 1303
>At5g58380 [T] KOG0583 Serine/threonine protein kinase
Length = 464
Score = 72.8 bits (177), Expect = 2e-12
Identities = 83/291 (28%), Positives = 136/291 (46%), Gaps = 47/291 (16%)
Query: 39 THRCEILEHLAEGGFANIYKVKFLELTNEMDA--GIDS-KLLKAGDIACLKRVIVPDENG 95
T + ++ L +G FA +Y + + LTN+ A ID K++K G I +KR
Sbjct: 9 TDKYDVGRLLGQGTFAKVYYGRSI-LTNQSVAIKMIDKEKVMKVGLIEQIKR-------- 59
Query: 96 LNELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKL 155
E+ M+ R PN+V+ Y+ A++ I +ME C L NK+
Sbjct: 60 ------EISVMRIAR-HPNVVELYEVMATKT-------RIYFVMEYCKGGELF----NKV 101
Query: 156 AT-KLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMC 214
A KL + K Y + NA+ H + HRDIK EN+L+D ++N K+ DFG +++
Sbjct: 102 AKGKLRDDVAWKYFYQLINAVDFCH--SREVYHRDIKPENLLLDDNENLKVSDFGLSALA 159
Query: 215 FPIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTT 274
QD + T TP Y +PE+I+ R K+DIW+ G+ L+ LL
Sbjct: 160 ---DCKRQDGLLHT----TCGTPAYVAPEVIN--RKGYDGTKADIWSCGVVLFVLLAGYL 210
Query: 275 PFELTGQFAILH----SKYEIPQNGYSSKLINLIIIMLAENPSLRPNIYQV 321
PF + + + ++ P + ++ ++ L+ ML NP R I ++
Sbjct: 211 PFHDSNLMEMYRKIGKADFKAP-SWFAPEVRRLLCKMLDPNPETRITIARI 260
>YHR102w [T] KOG0201 Serine/threonine protein kinase
Length = 1080
Score = 72.4 bits (176), Expect = 3e-12
Identities = 67/245 (27%), Positives = 110/245 (44%), Gaps = 29/245 (11%)
Query: 77 LKAGDIACLKRV-IVPDENGLNELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEI 135
+K G + +K + + D + + +++ E++ + L+ NI +YY S +
Sbjct: 43 VKTGRVYAIKVLNLDSDSDEVEDVQREIQFLASLKQISNITRYYGSYLK-------DTSL 95
Query: 136 LLLMELCPKKSLLDYMNNKLATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENV 195
++ME C SL + K+ E I IM ++ A+ +H +IHRDIK NV
Sbjct: 96 WIIMEHCAGGSLRSLLR---PGKIDEKYIGVIMRELLVALKCIH--KDNVIHRDIKAANV 150
Query: 196 LVDKDDNFKLCDFGSTSMCFPIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINE 255
L+ + N KLCDFG + Q +A TP + +PE+I + +
Sbjct: 151 LITNEGNVKLCDFGVAAQVNQTSLRRQTMA---------GTPYWMAPEVI--MEGVYYDT 199
Query: 256 KSDIWALGIFLYKLLFYTTPF----ELTGQFAILHSK-YEIPQNGYSSKLINLIIIMLAE 310
K DIW+LGI Y++ P+ L I+ SK + YS+ L I + L E
Sbjct: 200 KVDIWSLGITTYEIATGNPPYCDVEALRAMQLIIKSKPPRLEDRSYSTSLKEFIALCLDE 259
Query: 311 NPSLR 315
+P R
Sbjct: 260 DPKER 264
>At3g06630 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 671
Score = 72.4 bits (176), Expect = 3e-12
Identities = 54/208 (25%), Positives = 100/208 (47%), Gaps = 27/208 (12%)
Query: 93 ENGLNELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMN 152
E+ + EV MK+LR PN++ + + S + ++ E P+ SL +
Sbjct: 470 ESVIKSFEKEVSLMKRLR-HPNVLLFMGAVTSPQ-------RLCIVSEFVPRGSLFRLLQ 521
Query: 153 NKLATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTS 212
++ KL + + D++ + +H P+IHRD+K N+LVD++ K+ DFG +
Sbjct: 522 RSMS-KLDWRRRINMALDIARGMNYLHCCSPPIIHRDLKSSNLLVDRNWTVKVADFGLSR 580
Query: 213 MCFPIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFY 272
+ HQ + TPQ+ +PE++ R +EKSDI++ G+ L++L
Sbjct: 581 I------KHQTYLTSKSG---KGTPQWMAPEVL---RNESADEKSDIYSFGVVLWELATE 628
Query: 273 TTPFE------LTGQFAILHSKYEIPQN 294
P+E + G ++ + EIP++
Sbjct: 629 KIPWENLNSMQVIGAVGFMNQRLEIPKD 656
>At1g61590 [T] KOG1187 Serine/threonine protein kinase
Length = 424
Score = 72.4 bits (176), Expect = 3e-12
Identities = 63/223 (28%), Positives = 102/223 (45%), Gaps = 27/223 (12%)
Query: 48 LAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNELRNEVETMK 107
L EGGF +YK + + LKA +A +K + + G E +EV +
Sbjct: 105 LGEGGFGKVYKGYVDDYLRQS--------LKAQPVA-VKLLDIEGLQGHREWLSEVIFLG 155
Query: 108 QLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLTEAEILKI 167
QL+ PN+V+ E +L+ E P+ SL +++ +++ L A LKI
Sbjct: 156 QLK-HPNLVKLIGYCCEEE-------ERVLIYEFMPRGSLENHLFRRISLSLPWATRLKI 207
Query: 168 MYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTHQDIAVL 227
+ +A +H L +P+I+RD K N+L+D D KL DFG M +H V+
Sbjct: 208 AVAAAKGLAFLHDLESPIIYRDFKTSNILLDSDFTAKLSDFGLAKMGPEGSKSHVTTRVM 267
Query: 228 TNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLL 270
Y + P+Y S + KSD+++ G+ L +LL
Sbjct: 268 --GTYGYAAPEYVSTG--------HLTTKSDVYSYGVVLLELL 300
>SPAC1F5.09c [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 589
Score = 72.0 bits (175), Expect = 3e-12
Identities = 65/230 (28%), Positives = 105/230 (45%), Gaps = 36/230 (15%)
Query: 48 LAEGGFANIYKVKFLELTNEMDAGI-DSKLLKAGDIACLKRVIVPDENGLNELRNEVETM 106
L +G ++Y K + GI DS +K+ D+ C R + + NE+ M
Sbjct: 315 LGQGASGSVYLAK---VVGGKQLGIFDSVAIKSIDLQCQTRKEL--------ILNEITVM 363
Query: 107 KQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLTEAEILK 166
++ PNIV Y DS R + ++ME SL D + +KLTEA+I +
Sbjct: 364 RESI-HPNIVTYLDSFLVRER------HLWVVMEYMNAGSLTDIIEK---SKLTEAQIAR 413
Query: 167 IMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTHQDIAV 226
I + I +H +IHRDIK +NVL+D N K+ DFG C + +
Sbjct: 414 ICLETCKGIQHLH--ARNIIHRDIKSDNVLLDNSGNIKITDFG---FCARLSNR------ 462
Query: 227 LTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTPF 276
+ + TP + +PE++ + K DIW+LGI + +++ P+
Sbjct: 463 TNKRVTMVGTPYWMAPEVV---KQNEYGTKVDIWSLGIMIIEMIENEPPY 509
>ECU01g0630 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 488
Score = 72.0 bits (175), Expect = 3e-12
Identities = 60/232 (25%), Positives = 110/232 (46%), Gaps = 27/232 (11%)
Query: 98 ELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLAT 157
+L +E+ +L +PN+V+ Y S S + +++ELC + +L + K
Sbjct: 83 KLESEIAIHSKL-DNPNVVKMYRSFRSSE-------YVFMVLELCERGALDALL--KRNG 132
Query: 158 KLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPI 217
KL E + + + + +H ++HRD+K+ N+ +D N K+ DFG +++
Sbjct: 133 KLKERHVARFVKQTVEGLIYLHN-SVSVVHRDLKLGNLFLDSKFNVKIGDFGLSAV---- 187
Query: 218 VSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTPFE 277
I + + TP Y +PE++ + + ++DIW+LG+ +Y LL PF+
Sbjct: 188 ------IKDGEKKVTMCGTPNYIAPEVL-FGKASGHSFEADIWSLGVIIYTLLVGVPPFQ 240
Query: 278 LTGQFAILH----SKYEIPQN-GYSSKLINLIIIMLAENPSLRPNIYQVMHH 324
I + Y P+N SS+ I+LI +L NP RP + ++ H
Sbjct: 241 KKNVEDIYKMIKLNNYIFPENCDLSSEAIDLITQILNTNPLERPTLEHILSH 292
>CE26649 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 648
Score = 72.0 bits (175), Expect = 3e-12
Identities = 75/278 (26%), Positives = 130/278 (45%), Gaps = 42/278 (15%)
Query: 48 LAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNELRNEVETMK 107
L +GGFA+ Y ELTN ++ + AG + + + ++ + +++ EV+ +
Sbjct: 44 LGKGGFAHCY-----ELTNRA-----TREVVAGKV--VPKSMLVKQYQRDKMTQEVQIHR 91
Query: 108 QLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLTEAEILKI 167
+L G NIV+ ++ + + +ELC ++SL++ + A +TE E
Sbjct: 92 EL-GHINIVKLFNFFEDN-------LNVYITLELCARRSLMELHKRRKA--VTEPEARYF 141
Query: 168 MYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTHQDIAVL 227
+ + + + +H L +IHRD+K+ N+ ++ D K+ DFG + V+ + L
Sbjct: 142 THQIVDGVLYLHDLN--IIHRDMKLGNLFLNDDLVVKIGDFGLATT----VNGDERKKTL 195
Query: 228 TNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTPFELTG----QFA 283
TP Y +PE+++ + + DIWA+G LY LLF PFE
Sbjct: 196 CG------TPNYIAPEVLNK---AGHSFEVDIWAVGCILYILLFGQPPFESKSLEETYSR 246
Query: 284 ILHSKYEIPQNGYSSKLINLIIIMLAENPSLRPNIYQV 321
I H+ Y IP + +LI ML P+ RP QV
Sbjct: 247 IRHNNYTIPSIA-TQPAASLIRKMLDPEPTRRPTAKQV 283
>CE05507 [T] KOG0603 Ribosomal protein S6 kinase
Length = 785
Score = 72.0 bits (175), Expect = 3e-12
Identities = 67/260 (25%), Positives = 118/260 (44%), Gaps = 45/260 (17%)
Query: 97 NELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLA 156
++ + E ++ ++G PNIVQ +D + S L+ME+ LL+ +
Sbjct: 419 SQAQREARILEMVQGHPNIVQLHDVH-------SDPLHFYLVMEILTGNELLERIRK--L 469
Query: 157 TKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVL---VDKDDNFKLCDFG---- 209
+ TE+E IM + +A+ +H ++HRD+K EN+L +D +L DFG
Sbjct: 470 ERFTESEAADIMRQLVSAVKYLH--DKRIVHRDLKPENILFESIDSSARLRLVDFGFARL 527
Query: 210 -STSMCFPIVSTH---QDIAVLTNNIYVHT-----TPQYRSPEMIDLYRCLP-INEKSDI 259
SM + S + ++ +N +H+ T QY +PE++D+ P NE+ D+
Sbjct: 528 LPNSMEQQLKSVQVLRKMYGLIAHNHSLHSETPCFTLQYAAPEVLDVGDSQPEYNEQCDL 587
Query: 260 WALGIFLYKLLFYTTPFELTGQFAILHSKYEIPQ--------------NGYSSKLINLII 305
W+LG+ L+ +L PF + S EI Q S+ NLI
Sbjct: 588 WSLGVVLFTMLSGQVPFHARSR---QESATEIMQRICRAEFSFTGDAWTNVSADAKNLIT 644
Query: 306 IMLAENPSLRPNIYQVMHHV 325
+L +P R ++ ++ H+
Sbjct: 645 GLLTVDPKKRLSMQELTAHM 664
Score = 57.0 bits (136), Expect = 1e-07
Identities = 60/243 (24%), Positives = 112/243 (45%), Gaps = 40/243 (16%)
Query: 44 ILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNELRNEV 103
+L L +G + ++ V+ + G D + A + RV+ + L E
Sbjct: 19 LLRVLGKGAYGKVFLVRKV-------GGKDHNTIYAMKVLRKTRVLTKQKT-LEHTMAER 70
Query: 104 ETMKQLRGSP---NIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLT 160
+ +++LRG+P N+ + ++ H ++ME L ++ ++ L
Sbjct: 71 QVLERLRGTPFLVNLFYAFQTDTKLH----------IVMEYVRGGELFTHLCSRGHFDLE 120
Query: 161 EAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVST 220
A ++ ++ AI +H +I+RD+K+EN+L+D++ + KL DFG + + P
Sbjct: 121 AARF--VIAELVVAIDSLHQ--RKVIYRDLKLENILLDEEGHVKLTDFGLSKLFLP---G 173
Query: 221 HQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDI---WALGIFLYKLLFYTTPFE 277
D A N Y T +Y SPE+I+ P SD+ W+LG+ ++LL +PF
Sbjct: 174 ELDRA----NSYCGTI-EYMSPEVIN----RPEGGYSDVVDWWSLGVISFELLTGCSPFT 224
Query: 278 LTG 280
+ G
Sbjct: 225 VDG 227
>At4g14580 [T] KOG0583 Serine/threonine protein kinase
Length = 426
Score = 72.0 bits (175), Expect = 3e-12
Identities = 69/298 (23%), Positives = 133/298 (44%), Gaps = 65/298 (21%)
Query: 43 EILEHLAEGGFANIY-----------KVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVP 91
E+ L G FA ++ +K ++ +D+G++ ++++
Sbjct: 22 ELGRRLGSGSFAKVHVARSISTGELVAIKIIDKQKTIDSGMEPRIIR------------- 68
Query: 92 DENGLNELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYM 151
E+E M++L PN+++ ++ A++ +I L++E L +
Sbjct: 69 ----------EIEAMRRLHNHPNVLKIHEVMATKS-------KIYLVVEYAAGGELFTKL 111
Query: 152 NNKLATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGST 211
+L E+ + +++A++ H + HRD+K +N+L+DK N K+ DFG +
Sbjct: 112 IR--FGRLNESAARRYFQQLASALSFCHR--DGIAHRDVKPQNLLLDKQGNLKVSDFGLS 167
Query: 212 SMCFPIVSTHQDIAVLTNNIYVHT---TPQYRSPEMIDLYRCLPINEKSDIWALGIFLYK 268
++ H+ +NN +HT TP Y +PE+I K+D W+ G+FL+
Sbjct: 168 AL-----PEHR-----SNNGLLHTACGTPAYTAPEVIAQRGY--DGAKADAWSCGVFLFV 215
Query: 269 LLFYTTPFE---LTGQFAILHSK-YEIPQNGYSSKLINLIIIMLAENPSLRPNIYQVM 322
LL PF+ + + +H + Y P + S ++I +L NP R +I VM
Sbjct: 216 LLAGYVPFDDANIVAMYRKIHKRDYRFP-SWISKPARSIIYKLLDPNPETRMSIEAVM 272
>Hs5174701 [T] KOG0579 Ste20-like serine/threonine protein kinase
Length = 968
Score = 71.6 bits (174), Expect = 4e-12
Identities = 73/290 (25%), Positives = 128/290 (43%), Gaps = 43/290 (14%)
Query: 43 EILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNELRNE 102
EI+ L +G F +YK K E G +A K + E L + E
Sbjct: 37 EIVGELGDGAFGKVYKAKNKE---------------TGALAAAKVIETKSEEELEDYIVE 81
Query: 103 VETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLTEA 162
+E + P IV+ + + DG ++ +++E CP ++ D + +L LTE
Sbjct: 82 IEILATC-DHPYIVKLL---GAYYHDG----KLWIMIEFCPGGAV-DAIMLELDRGLTEP 132
Query: 163 EILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTHQ 222
+I + + A+ +H +IHRD+K NVL+ + + +L DFG ++ +
Sbjct: 133 QIQVVCRQMLEALNFLH--SKRIIHRDLKAGNVLMTLEGDIRLADFGVSA---------K 181
Query: 223 DIAVLTNNIYVHTTPQYRSPE--MIDLYRCLPINEKSDIWALGIFLYKLLFYTTP-FELT 279
++ L TP + +PE M + + P + K+DIW+LGI L ++ P EL
Sbjct: 182 NLKTLQKRDSFIGTPYWMAPEVVMCETMKDTPYDYKADIWSLGITLIEMAQIEPPHHELN 241
Query: 280 GQFAILHSKYEIP-----QNGYSSKLINLIIIMLAENPSLRPNIYQVMHH 324
+L P + +S + + + I L +NP RP+ Q++ H
Sbjct: 242 PMRVLLKIAKSDPPTLLTPSKWSVEFRDFLKIALDKNPETRPSAAQLLEH 291
>Hs15451902 [T] KOG0576 Mitogen-activated protein kinase kinase kinase kinase
(MAP4K) germinal center kinase family
Length = 894
Score = 71.6 bits (174), Expect = 4e-12
Identities = 67/291 (23%), Positives = 128/291 (43%), Gaps = 46/291 (15%)
Query: 43 EILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNELRNE 102
E+++ + G + ++YK ++ + G++A +K + + ++ E
Sbjct: 17 ELIQRIGSGTYGDVYK---------------ARNVNTGELAAIKVIKLEPGEDFAVVQQE 61
Query: 103 VETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLTEA 162
+ MK + PNIV Y+ S R ++ + ME C SL D + + L+E
Sbjct: 62 IIMMKDCK-HPNIVAYFGSYLRRD-------KLWICMEFCGGGSLQDIYH--VTGPLSE- 110
Query: 163 EILKIMYDVSNAIAQMHYLPTP-LIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTH 221
L+I Y + ++YL + +HRDIK N+L+ + + KL DFG ++
Sbjct: 111 --LQIAYVSRETLQGLYYLHSKGKMHRDIKGANILLTDNGHVKLADFGVSA--------- 159
Query: 222 QDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTPF----E 277
Q A + TP + +PE+ + R N+ D+WA+GI +L P
Sbjct: 160 QITATIAKRKSFIGTPYWMAPEVAAVERKGGYNQLCDLWAVGITAIELAELQPPMFDLHP 219
Query: 278 LTGQFAILHSKYEIP----QNGYSSKLINLIIIMLAENPSLRPNIYQVMHH 324
+ F + S ++ P + +S+ + + + L +NP RP +++ H
Sbjct: 220 MRALFLMTKSNFQPPKLKDKMKWSNSFHHFVKMALTKNPKKRPTAEKLLQH 270
>Hs14589909 [T] KOG0576 Mitogen-activated protein kinase kinase kinase kinase
(MAP4K) germinal center kinase family
Length = 846
Score = 71.6 bits (174), Expect = 4e-12
Identities = 65/290 (22%), Positives = 126/290 (43%), Gaps = 44/290 (15%)
Query: 43 EILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNELRNE 102
E+++ + G + ++YK + + G++A +K + + + + ++ E
Sbjct: 21 ELVQRVGSGTYGDVYKARNVH---------------TGELAAVKIIKLEPGDDFSLIQQE 65
Query: 103 VETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLTEA 162
+ +K+ + NIV Y+ S SR ++ + ME C SL D + + L+E
Sbjct: 66 IFMVKECKHC-NIVAYFGSYLSRE-------KLWICMEYCGGGSLQDIYH--VTGPLSEL 115
Query: 163 EILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTHQ 222
+I + + +A +H +HRDIK N+L+ + KL DFG + ++ +
Sbjct: 116 QIAYVCRETLQGLAYLH--TKGKMHRDIKGANILLTDHGDVKLADFGVAAKITATIAKRK 173
Query: 223 DIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTPF----EL 278
TP + +PE+ + + N+ DIWA+GI +L P +
Sbjct: 174 SFI---------GTPYWMAPEVAAVEKNGGYNQLCDIWAVGITAIELGELQPPMFDLHPM 224
Query: 279 TGQFAILHSKYEIP----QNGYSSKLINLIIIMLAENPSLRPNIYQVMHH 324
F + S ++ P + +SS N + I L +NP RP +++ H
Sbjct: 225 RALFLMSKSNFQPPKLKDKTKWSSTFHNFVKIALTKNPKKRPTAERLLTH 274
>CE23702 [T] KOG4721 Serine/threonine protein kinase contains leucine zipper
domain
Length = 855
Score = 71.6 bits (174), Expect = 4e-12
Identities = 65/245 (26%), Positives = 117/245 (47%), Gaps = 33/245 (13%)
Query: 86 KRVIVPDENGLNELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKK 145
+ V V N L E E++ ++ LR NI+++ + SP + ++ME C K
Sbjct: 84 RTVAVKKVNQLKE--TEIKHLRHLRHQ-NIIEFLGVCSK-----SPCY--CIVMEYCSKG 133
Query: 146 SLLDYMNNKLATKLTEAEILKIMYDVSNAIAQMHYL-PTPLIHRDIKIENVLVDKDDNFK 204
L + ++ +T + + ++++ MHYL +IHRD+K N+L+ +D+ K
Sbjct: 134 QLCTVLKSR--NTITRELFAQWVKEIADG---MHYLHQNKVIHRDLKSPNILISAEDSIK 188
Query: 205 LCDFGSTSMCFPIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGI 264
+CDFG++ M + ST T + +PEMI + P NEK D+++ G+
Sbjct: 189 ICDFGTSHMQKKMDSTMMSFC---------GTVSWMAPEMI---KKQPCNEKVDVYSFGV 236
Query: 265 FLYKLLFYTTPFELTGQFAILH----SKYEIPQNGYSSK-LINLIIIMLAENPSLRPNIY 319
L+++L TP+ Q AI+ + +P + K L+ LI L++ RP+
Sbjct: 237 VLWEMLTRETPYANIAQMAIIFGVGTNILSLPMPEEAPKGLVLLIKQCLSQKGRNRPSFS 296
Query: 320 QVMHH 324
+ H
Sbjct: 297 HIRQH 301
>7290150 [T] KOG0583 Serine/threonine protein kinase
Length = 582
Score = 71.6 bits (174), Expect = 4e-12
Identities = 63/250 (25%), Positives = 119/250 (47%), Gaps = 35/250 (14%)
Query: 82 IACLKRVIVPDENGLNELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMEL 141
+ L R + + + ++R E++ +K R P+I++ Y ++ +I ++ME
Sbjct: 56 VKILNRQKIKSLDVVGKIRREIQNLKLFR-HPHIIKLYQVISTPS-------DIFMIMEY 107
Query: 142 CPKKSLLDYMNNKLATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDD 201
L DY+ KL E + + + + + H ++HRD+K EN+L+D +
Sbjct: 108 VSGGELFDYIVKH--GKLQEHQARRFFQQIISGVDYCHR--HMIVHRDLKPENLLLDHNM 163
Query: 202 NFKLCDFGSTSMCFPIVSTHQDIAVLTNNIYVHT---TPQYRSPEMIDLYRCLPINEKSD 258
+ K+ DFG ++M + + ++ T +P Y +PE+I L + D
Sbjct: 164 HVKIADFGLSNM-------------MLDGEFLRTSCGSPNYAAPEVIS--GKLYAGPEVD 208
Query: 259 IWALGIFLYKLLFYTTPFE---LTGQFAILHSK-YEIPQNGYSSKLINLIIIMLAENPSL 314
IW+ G+ LY LL T PF+ + F + S + IP+ + +++NL+ ML +P
Sbjct: 209 IWSCGVILYALLCGTLPFDDEHVPTLFRKIKSGIFPIPEY-LNKQVVNLVCQMLQVDPLK 267
Query: 315 RPNIYQVMHH 324
R NI ++ H
Sbjct: 268 RANIEEIKKH 277
>7290147 [T] KOG0583 Serine/threonine protein kinase
Length = 291
Score = 71.6 bits (174), Expect = 4e-12
Identities = 66/242 (27%), Positives = 113/242 (46%), Gaps = 34/242 (14%)
Query: 37 VGTHRCEILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPD-ENG 95
+G + + L +G F + FL NE+ + K+ C+KR+IV + +
Sbjct: 3 LGDSKLRAVRVLGQGTFGRV----FLCHQNEVRGQPERKV-------CVKRIIVRNPKTE 51
Query: 96 LNELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKL 155
L ++ EV + QLR P+IV++ S S + ++ME P +L D + +L
Sbjct: 52 LGLIKEEVYIISQLR-HPHIVEFLRSF-------SHAGTVNIVMEYVPNGTLRDVIQ-QL 102
Query: 156 ATKLTEAEILKIMYDVSNAIAQMHYLPTP-LIHRDIKIENVLVDKDDNFKLCDFGSTSMC 214
+ ++M + + + YL +IHRDIK EN+L+D +D K+ DFG ++
Sbjct: 103 PSGTGGVNQERLMGYFRDMVVGLEYLHIRCVIHRDIKPENMLLDANDRVKIADFGIANVH 162
Query: 215 FPIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTT 274
P + TP Y +PE + ++ KSD+W+LG+ LY+L +
Sbjct: 163 APSTQLQAGMG----------TPMYMAPEAMSSQG--KVDFKSDVWSLGLVLYELCLGRS 210
Query: 275 PF 276
PF
Sbjct: 211 PF 212
>CE27965 [T] KOG0574 STE20-like serine/threonine kinase MST
Length = 525
Score = 71.2 bits (173), Expect = 6e-12
Identities = 63/222 (28%), Positives = 104/222 (46%), Gaps = 40/222 (18%)
Query: 43 EILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNELRNE 102
+I+ L EG + +++K E +G + +K+V P + L E+ E
Sbjct: 64 DIVGKLGEGSYGSVHKAIHRE---------------SGHVLAIKKV--PVDTDLQEIIKE 106
Query: 103 VETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLTEA 162
+ M+Q + S +V+YY S +H D + ++ME C S+ D M + L+E
Sbjct: 107 ISIMQQCK-SKYVVKYYGSYF-KHSD------LWIVMEYCGAGSISDIMRAR-RKPLSEQ 157
Query: 163 EILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTHQ 222
EI ++ D + +H L IHRDIK N+L++ D KL DFG +
Sbjct: 158 EISAVLRDTLKGLQYLHDLKK--IHRDIKAGNILLNTDGIAKLADFG-------VAGQLT 208
Query: 223 DIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGI 264
D N + TP + +PE+I+ + + K+DIW+LGI
Sbjct: 209 DTMAKRNTVI--GTPFWMAPEVIEE---IGYDTKADIWSLGI 245
>CE27726 [T] KOG0574 STE20-like serine/threonine kinase MST
Length = 640
Score = 71.2 bits (173), Expect = 6e-12
Identities = 63/222 (28%), Positives = 104/222 (46%), Gaps = 40/222 (18%)
Query: 43 EILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNELRNE 102
+I+ L EG + +++K E +G + +K+V P + L E+ E
Sbjct: 36 DIVGKLGEGSYGSVHKAIHRE---------------SGHVLAIKKV--PVDTDLQEIIKE 78
Query: 103 VETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLTEA 162
+ M+Q + S +V+YY S +H D + ++ME C S+ D M + L+E
Sbjct: 79 ISIMQQCK-SKYVVKYYGSYF-KHSD------LWIVMEYCGAGSISDIMRAR-RKPLSEQ 129
Query: 163 EILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTHQ 222
EI ++ D + +H L IHRDIK N+L++ D KL DFG +
Sbjct: 130 EISAVLRDTLKGLQYLHDLKK--IHRDIKAGNILLNTDGIAKLADFG-------VAGQLT 180
Query: 223 DIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGI 264
D N + TP + +PE+I+ + + K+DIW+LGI
Sbjct: 181 DTMAKRNTVI--GTPFWMAPEVIEE---IGYDTKADIWSLGI 217
>CE27082 [T] KOG0574 STE20-like serine/threonine kinase MST
Length = 421
Score = 71.2 bits (173), Expect = 6e-12
Identities = 63/222 (28%), Positives = 104/222 (46%), Gaps = 40/222 (18%)
Query: 43 EILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNELRNE 102
+I+ L EG + +++K E +G + +K+V P + L E+ E
Sbjct: 36 DIVGKLGEGSYGSVHKAIHRE---------------SGHVLAIKKV--PVDTDLQEIIKE 78
Query: 103 VETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLTEA 162
+ M+Q + S +V+YY S +H D + ++ME C S+ D M + L+E
Sbjct: 79 ISIMQQCK-SKYVVKYYGSYF-KHSD------LWIVMEYCGAGSISDIMRAR-RKPLSEQ 129
Query: 163 EILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTHQ 222
EI ++ D + +H L IHRDIK N+L++ D KL DFG +
Sbjct: 130 EISAVLRDTLKGLQYLHDLKK--IHRDIKAGNILLNTDGIAKLADFG-------VAGQLT 180
Query: 223 DIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGI 264
D N + TP + +PE+I+ + + K+DIW+LGI
Sbjct: 181 DTMAKRNTVI--GTPFWMAPEVIEE---IGYDTKADIWSLGI 217
>CE07064 [T] KOG0574 STE20-like serine/threonine kinase MST
Length = 523
Score = 71.2 bits (173), Expect = 6e-12
Identities = 63/222 (28%), Positives = 104/222 (46%), Gaps = 40/222 (18%)
Query: 43 EILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNELRNE 102
+I+ L EG + +++K E +G + +K+V P + L E+ E
Sbjct: 64 DIVGKLGEGSYGSVHKAIHRE---------------SGHVLAIKKV--PVDTDLQEIIKE 106
Query: 103 VETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLTEA 162
+ M+Q + S +V+YY S +H D + ++ME C S+ D M + L+E
Sbjct: 107 ISIMQQCK-SKYVVKYYGSYF-KHSD------LWIVMEYCGAGSISDIMRAR-RKPLSEQ 157
Query: 163 EILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTHQ 222
EI ++ D + +H L IHRDIK N+L++ D KL DFG +
Sbjct: 158 EISAVLRDTLKGLQYLHDLKK--IHRDIKAGNILLNTDGIAKLADFG-------VAGQLT 208
Query: 223 DIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGI 264
D N + TP + +PE+I+ + + K+DIW+LGI
Sbjct: 209 DTMAKRNTVI--GTPFWMAPEVIEE---IGYDTKADIWSLGI 245
>At5g39440 [T] KOG0583 Serine/threonine protein kinase
Length = 494
Score = 71.2 bits (173), Expect = 6e-12
Identities = 64/234 (27%), Positives = 111/234 (47%), Gaps = 36/234 (15%)
Query: 98 ELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLAT 157
+++ E++ ++ L P+I++ Y+ + + +I ++ME L DY+ K
Sbjct: 63 KVQREIKILRFLM-HPHIIRQYEVIETPN-------DIYVVMEYVKSGELFDYIVEK--G 112
Query: 158 KLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPI 217
KL E E + + + + H ++HRD+K ENVL+D N K+ DFG ++
Sbjct: 113 KLQEDEARHLFQQIISGVEYCHR--NMIVHRDLKPENVLLDSQCNIKIVDFGLSN----- 165
Query: 218 VSTHQDIAVLTNNIYVHT---TPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTT 274
V+ + ++ T +P Y +PE+I P DIW+ G+ LY LL T
Sbjct: 166 --------VMHDGHFLKTSCGSPNYAAPEVIS---GKPYGPDVDIWSCGVILYALLCGTL 214
Query: 275 PFE---LTGQF-AILHSKYEIPQNGYSSKLINLIIIMLAENPSLRPNIYQVMHH 324
PF+ + F I Y +P N S +LI ML +P++R +I ++ H
Sbjct: 215 PFDDENIPNVFEKIKRGMYTLP-NHLSHFARDLIPRMLMVDPTMRISITEIRQH 267
>At1g53165 [T] KOG0201 Serine/threonine protein kinase
Length = 1007
Score = 71.2 bits (173), Expect = 6e-12
Identities = 73/298 (24%), Positives = 127/298 (42%), Gaps = 48/298 (16%)
Query: 34 QVVVGTHRCEILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDE 93
Q GT R E + G F ++YK D++L K D+A + E
Sbjct: 335 QEAAGT-RFSQFELIGRGSFGDVYKA------------FDTELNK--DVAIKVIDLEESE 379
Query: 94 NGLNELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNN 153
+ + +++ E+ + Q R P I +YY S + ++ ++ME S+ D +
Sbjct: 380 DEIEDIQKEISVLSQCR-CPYITEYYGSYLHQT-------KLWIIMEYMAGGSVADLLQP 431
Query: 154 KLATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSM 213
L E I I D+ +A+ +H IHRDIK N+L+ ++ + K+ DFG ++
Sbjct: 432 --GNPLDEISIACITRDLLHAVEYLH--AEGKIHRDIKAANILLSENGDVKVADFGVSAQ 487
Query: 214 CFPIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYT 273
+S + TP + +PE+I NEK+DIW+LGI + ++
Sbjct: 488 LTRTISRRKTFV---------GTPFWMAPEVIQ--NSEGYNEKADIWSLGITMIEMAKGE 536
Query: 274 TPFELTGQFAILHSKYEIPQNG-------YSSKLINLIIIMLAENPSLRPNIYQVMHH 324
P +L + IP+ +S L + L + P+ RPN +++ H
Sbjct: 537 PPLADLHPMRVL---FIIPRESPPQLDEHFSRPLKEFVSFCLKKAPAERPNAKELLKH 591
>CE16081 [T] KOG0583 Serine/threonine protein kinase
Length = 334
Score = 70.9 bits (172), Expect = 8e-12
Identities = 74/279 (26%), Positives = 120/279 (42%), Gaps = 38/279 (13%)
Query: 58 KVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVP-------DENGLNELRNEVETMKQLR 110
++ F L E+ AG SK+ ++V V D L E++ M+++
Sbjct: 45 RIGFYRLGKELGAGNFSKVKLGVHQLTKEKVAVKIMDKAKMDAKAQKLLSREIQAMEEMN 104
Query: 111 GSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLTEAEILKIMYD 170
PNIV+ ++ + + L++E L Y++ + KLTE + +
Sbjct: 105 -HPNIVKLFEVVETLT-------RVHLVIEYASGGELYTYVHER--GKLTEGDAKPLFAQ 154
Query: 171 VSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTHQDIAVLTNN 230
+ +A++ MH ++HRDIK ENV+ + KL DFG + +V Q +
Sbjct: 155 IVSAVSHMH--SRNIVHRDIKAENVMFSSPNTVKLVDFGFSC----LVDREQMLRTFCG- 207
Query: 231 IYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTPFELTG----QFAILH 286
+P Y +PE+ E D+WALG+ L+ +L TPF+ + I
Sbjct: 208 -----SPPYAAPELFQ--DTSYAGELVDVWALGVLLFFMLIGVTPFKAETVPDMKVLITA 260
Query: 287 SKYEIPQNGYSSKL-INLIIIMLAENPSLRPNIYQVMHH 324
KY+IP Y S L LI ML + R +I V H
Sbjct: 261 GKYQIPD--YVSLLATELIKSMLKTDTGQRADIDSVKKH 297
>CE28643 [T] KOG0583 Serine/threonine protein kinase
Length = 564
Score = 70.5 bits (171), Expect = 1e-11
Identities = 60/249 (24%), Positives = 114/249 (45%), Gaps = 33/249 (13%)
Query: 82 IACLKRVIVPDENGLNELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMEL 141
+ L R + + + ++R E++ + R P+I++ Y ++ +I ++ME
Sbjct: 53 VKILNRQKIKSLDVVGKIRREIQNLSLFR-HPHIIRLYQVISTPS-------DIFMIMEH 104
Query: 142 CPKKSLLDYMNNKLATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDD 201
L DY+ +L AE + + + + H ++HRD+K EN+L+D+ +
Sbjct: 105 VSGGELFDYIVKH--GRLKTAEARRFFQQIISGVDYCHR--HMVVHRDLKPENLLLDEQN 160
Query: 202 NFKLCDFGSTSMCFPIVSTHQDIAVLTNNIYVHT---TPQYRSPEMIDLYRCLPINEKSD 258
N K+ DFG ++ ++T+ ++ T +P Y +PE+I L + D
Sbjct: 161 NVKIADFGLSN-------------IMTDGDFLRTSCGSPNYAAPEVIS--GKLYAGPEVD 205
Query: 259 IWALGIFLYKLLFYTTPFE---LTGQFAILHSKYEIPQNGYSSKLINLIIIMLAENPSLR 315
+W+ G+ LY LL T PF+ + F + S + ++NL+ ML +P R
Sbjct: 206 VWSCGVILYALLCGTLPFDDEHVPSLFRKIKSGVFPTPDFLERPIVNLLHHMLCVDPMKR 265
Query: 316 PNIYQVMHH 324
I V+ H
Sbjct: 266 ATIKDVIAH 274
>CE07458 [T] KOG0583 Serine/threonine protein kinase
Length = 562
Score = 70.5 bits (171), Expect = 1e-11
Identities = 60/249 (24%), Positives = 114/249 (45%), Gaps = 33/249 (13%)
Query: 82 IACLKRVIVPDENGLNELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMEL 141
+ L R + + + ++R E++ + R P+I++ Y ++ +I ++ME
Sbjct: 53 VKILNRQKIKSLDVVGKIRREIQNLSLFR-HPHIIRLYQVISTPS-------DIFMIMEH 104
Query: 142 CPKKSLLDYMNNKLATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDD 201
L DY+ +L AE + + + + H ++HRD+K EN+L+D+ +
Sbjct: 105 VSGGELFDYIVKH--GRLKTAEARRFFQQIISGVDYCHR--HMVVHRDLKPENLLLDEQN 160
Query: 202 NFKLCDFGSTSMCFPIVSTHQDIAVLTNNIYVHT---TPQYRSPEMIDLYRCLPINEKSD 258
N K+ DFG ++ ++T+ ++ T +P Y +PE+I L + D
Sbjct: 161 NVKIADFGLSN-------------IMTDGDFLRTSCGSPNYAAPEVIS--GKLYAGPEVD 205
Query: 259 IWALGIFLYKLLFYTTPFE---LTGQFAILHSKYEIPQNGYSSKLINLIIIMLAENPSLR 315
+W+ G+ LY LL T PF+ + F + S + ++NL+ ML +P R
Sbjct: 206 VWSCGVILYALLCGTLPFDDEHVPSLFRKIKSGVFPTPDFLERPIVNLLHHMLCVDPMKR 265
Query: 316 PNIYQVMHH 324
I V+ H
Sbjct: 266 ATIKDVIAH 274
>At5g28680 [T] KOG1187 Serine/threonine protein kinase
Length = 858
Score = 70.5 bits (171), Expect = 1e-11
Identities = 64/275 (23%), Positives = 120/275 (43%), Gaps = 48/275 (17%)
Query: 2 SKSDTISRPNSVAHTAATSAMIPNSHLLSPNTQVVVGTHRCEILEHLAEGGFANIYKVKF 61
+KS + N+ +H + +A + LS ++ GTH + + GGF +YK
Sbjct: 484 TKSTISGKSNNGSHLSNLAAGLCRRFSLS---EIKHGTHNFDESNVIGVGGFGKVYK--- 537
Query: 62 LELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNELRNEVETMKQLRGSP--NIVQYY 119
++ G +K+ E GLNE E+E + +LR +++ Y
Sbjct: 538 -------------GVIDGGTKVAIKKSNPNSEQGLNEFETEIELLSRLRHKHLVSLIGYC 584
Query: 120 DSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLTEAEILKIMYDVSNAIAQMH 179
D G E+ L+ + +L +++ N +LT L+I + + H
Sbjct: 585 DE----------GGEMCLIYDYMSLGTLREHLYNTKRPQLTWKRRLEIAIGAARGL---H 631
Query: 180 YLPT----PLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTHQDIAVLTNNIYVHT 235
YL T +IHRD+K N+L+D++ K+ DFG + + H + + + +
Sbjct: 632 YLHTGAKYTIIHRDVKTTNILLDENWVAKVSDFGLSKTGPNMNGGH--VTTVVKGSFGYL 689
Query: 236 TPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLL 270
P+Y +R + EKSD+++ G+ L+++L
Sbjct: 690 DPEY--------FRRQQLTEKSDVYSFGVVLFEVL 716
>At2g38490 [T] KOG0583 Serine/threonine protein kinase
Length = 431
Score = 70.5 bits (171), Expect = 1e-11
Identities = 78/281 (27%), Positives = 133/281 (46%), Gaps = 43/281 (15%)
Query: 48 LAEGGFANIYKVKFLELTNEMDA--GIDSKLLKAGDIACLKRVIVPDENGLNELRNEVET 105
L G FA +Y+ + L+ E A + K LK G A +KR E+
Sbjct: 34 LGSGAFAKVYQAEDLQNGGESVAIKVVQKKRLKDGLTAHVKR--------------EISV 79
Query: 106 MKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLTEAEIL 165
M++LR P+IV + A++ +I +MEL L + + + TE+
Sbjct: 80 MRRLR-HPHIVLLSEVLATKT-------KIYFVMELAKGGELFSRVTSN---RFTESLSR 128
Query: 166 KIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTHQDIA 225
K + +A+ H + HRD+K EN+L+D++ + K+ DFG ++M I H D
Sbjct: 129 KYFRQLISAVRYCH--ARGVFHRDLKPENLLLDENRDLKVSDFGLSAMKEQI---HPDGM 183
Query: 226 VLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTPF---ELTGQF 282
+ T + TP Y +PE+ L + K+DIW+ G+ L+ L PF + G +
Sbjct: 184 LHT----LCGTPAYVAPEL--LLKKGYDGSKADIWSCGVVLFLLNAGYLPFRDPNIMGLY 237
Query: 283 AILH-SKYEIPQNGYSSKLINLIIIMLAENPSLRPNIYQVM 322
+H ++Y++P + SS L L+ +L NP LR + +++
Sbjct: 238 RKIHKAQYKLP-DWTSSDLRKLLRRLLEPNPELRITVEEIL 277
>SPCC320.12c [D] KOG0580 Serine/threonine protein kinase
Length = 384
Score = 70.1 bits (170), Expect = 1e-11
Identities = 68/232 (29%), Positives = 105/232 (44%), Gaps = 32/232 (13%)
Query: 98 ELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLAT 157
++R E+E LR NI++ Y I L++E + L Y + + A
Sbjct: 162 QVRREIEIQSNLRHK-NILRLYGHFHDEK-------RIYLILEFAGRGEL--YQHLRRAK 211
Query: 158 KLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPI 217
+ +E K ++ ++NA++ +H +IHRDIK EN+L+ D KL DFG
Sbjct: 212 RFSEEVASKYIFQMANALSYLH--KKHVIHRDIKPENILLGIDGEIKLSDFG-------- 261
Query: 218 VSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTPFE 277
S H A + T Y PEM++ EK D+W+LG+ Y+ L PFE
Sbjct: 262 WSVH---APSNRRTTLCGTLDYLPPEMVE---GKEHTEKVDLWSLGVLTYEFLVGAPPFE 315
Query: 278 -LTGQFA----ILHSKYEIPQNGYSSKLINLIIIMLAENPSLRPNIYQVMHH 324
++G A I +IP + +LI +L NP R ++ QVM H
Sbjct: 316 DMSGHSATYKRIAKVDLKIP-SFVPPDARDLISRLLQHNPEKRMSLEQVMRH 366
>SPAC3H1.13 [KIT] KOG2345 Serine/threonine protein kinase/TGF-beta stimulated
factor
Length = 344
Score = 70.1 bits (170), Expect = 1e-11
Identities = 78/348 (22%), Positives = 143/348 (40%), Gaps = 57/348 (16%)
Query: 18 ATSAMIPNSHLLSPNTQVVVGTHRCEILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLL 77
A + P L N V + R I + L EGGFA +Y V+ ++NE KL
Sbjct: 8 ALDTLSPYISNLFDNDVVCINNERYRIQKLLGEGGFAFVYLVQ--NVSNE-------KLY 58
Query: 78 KAGDIACLKRVIVPDENGLNELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILL 137
I C G+ + E + ++ + S +++ Y + DGS + +
Sbjct: 59 ALKKIKCSF-----GNKGIKKAMKEADYHRKFK-SNYLLKSYTHQLVKEADGSEF--VYI 110
Query: 138 LMELCPKKSLLDYMNNK--LATKLTEAEILKIMYDVSNAIAQMH---------------- 179
L K S+ + N + ++E IL + A+ +H
Sbjct: 111 LFPYFAKGSVAQVIRNCDIEGSYISEKRILVWCSCLCKALQYLHENVAGDSPKQPEVNDL 170
Query: 180 ------YLP--------TPLIHRDIKIENVLVDKDDN-FKLCDFGSTSMCFPIVSTHQDI 224
+P IH DIK +N+L+ ++ L DFGS + S + +
Sbjct: 171 IMFDEPQVPQNTSNNNLVSYIHGDIKPDNLLLHENSREIVLTDFGSICLVPIFASNNSEA 230
Query: 225 AVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTPFEL------ 278
+ + + T +R+PE+ + I EK+DIW+ G LY ++F+ +PFE
Sbjct: 231 IAIQDKASENCTMPFRAPELFHVKAGSTITEKADIWSFGCTLYTIMFHASPFEREVSQGG 290
Query: 279 TGQFAILHSKYEIP-QNGYSSKLINLIIIMLAENPSLRPNIYQVMHHV 325
+ A+ +++Y P ++ YS+ L ++ L P+ RP+ +++ +
Sbjct: 291 SLALAVCNAQYSFPRKHPYSTLLCEIVEACLQREPNKRPSARELLSKI 338
>Hs20070158 [T] KOG0201 Serine/threonine protein kinase
Length = 443
Score = 70.1 bits (170), Expect = 1e-11
Identities = 73/287 (25%), Positives = 120/287 (41%), Gaps = 49/287 (17%)
Query: 45 LEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNELRNEVE 104
LE + +G F ++K GID++ K I + DE + +++ E+
Sbjct: 39 LEKIGKGSFGEVFK------------GIDNRTQKVVAIKIIDLEEAEDE--IEDIQQEIT 84
Query: 105 TMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLTEAEI 164
+ Q SP + +YY S ++ ++ME S LD + L E +I
Sbjct: 85 VLSQC-DSPYVTKYYGSYLK-------DTKLWIIMEYLGGGSALDLLE---PGPLDETQI 133
Query: 165 LKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTHQDI 224
I+ ++ + +H IHRDIK NVL+ + KL DFG V+
Sbjct: 134 ATILREILKGLDYLH--SEKKIHRDIKAANVLLSEHGEVKLADFG--------VAGQLTD 183
Query: 225 AVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTPFELTGQFAI 284
+ N +V TP + +PE+I + + K+DIW+LGI +L P +
Sbjct: 184 TQIKRNTFV-GTPFWMAPEVI---KQSAYDSKADIWSLGITAIELARGEPPHSELHPMKV 239
Query: 285 LHSKYEIPQN-------GYSSKLINLIIIMLAENPSLRPNIYQVMHH 324
L + IP+N YS L + L + PS RP +++ H
Sbjct: 240 L---FLIPKNNPPTLEGNYSKPLKEFVEACLNKEPSFRPTAKELLKH 283
>Hs17933758 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kinase beta
and related serine/threonine protein kinases
Length = 588
Score = 70.1 bits (170), Expect = 1e-11
Identities = 63/235 (26%), Positives = 111/235 (46%), Gaps = 27/235 (11%)
Query: 96 LNELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKL 155
+ ++ E+ +K+L PN+V+ + + D + ++ EL + +++ K
Sbjct: 230 IEQVYQEIAILKKL-DHPNVVKLVEVLDDPNED-----HLYMVFELVNQGPVMEVPTLK- 282
Query: 156 ATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCF 215
L+E + D+ I +HY +IHRDIK N+LV +D + K+ DFG ++
Sbjct: 283 --PLSEDQARFYFQDLIKGIEYLHY--QKIIHRDIKPSNLLVGEDGHIKIADFGVSN--- 335
Query: 216 PIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTP 275
A+L+N + TP + +PE + R + + D+WA+G+ LY +F P
Sbjct: 336 ---EFKGSDALLSNTV---GTPAFMAPESLSETRKIFSGKALDVWAMGVTLYCFVFGQCP 389
Query: 276 FELTGQFAILHSK-----YEIP-QNGYSSKLINLIIIMLAENPSLRPNIYQVMHH 324
F + + LHSK E P Q + L +LI ML +NP R + ++ H
Sbjct: 390 F-MDERIMCLHSKIKSQALEFPDQPDIAEDLKDLITRMLDKNPESRIVVPEIKLH 443
>7299536 [D] KOG0580 Serine/threonine protein kinase
Length = 411
Score = 70.1 bits (170), Expect = 1e-11
Identities = 77/282 (27%), Positives = 130/282 (45%), Gaps = 43/282 (15%)
Query: 48 LAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNELRNEVETMK 107
L G F N+Y L E + K+L KR I + N +++R E+E
Sbjct: 160 LGRGKFGNVY----LAREKESQFVVALKVL-------FKRQI-GESNVEHQVRREIEIQS 207
Query: 108 QLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLTEAEILKI 167
LR P+I++ Y A H D I L++E P+ +L + + + + E +
Sbjct: 208 HLR-HPHILRLY---AYFHDD----VRIYLILEYAPQGTLFNALQAQPMKRFDERQSATY 259
Query: 168 MYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTHQDIAVL 227
+ + +A+ +H +IHRDIK EN+L+ K+ DFG S H+ ++
Sbjct: 260 IQALCSALLYLH--ERDIIHRDIKPENLLLGHKGVLKIADFG--------WSVHEPNSM- 308
Query: 228 TNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLL-----FYTTPFELTGQF 282
+ + T Y PEM+ + P + D+W+LG+ ++LL FY+ ++ T +
Sbjct: 309 --RMTLCGTVDYLPPEMV---QGKPHTKNVDLWSLGVLCFELLVGHAPFYSKNYDETYK- 362
Query: 283 AILHSKYEIPQNGYSSKLINLIIIMLAENPSLRPNIYQVMHH 324
IL Y++P++ S +LI +L NP R + QVM H
Sbjct: 363 KILKVDYKLPEH-ISKAASHLISKLLVLNPQHRLPLDQVMVH 403
>YAR019c [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 974
Score = 69.7 bits (169), Expect = 2e-11
Identities = 64/248 (25%), Positives = 114/248 (45%), Gaps = 31/248 (12%)
Query: 82 IACLKRVIVPDENGLNELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMEL 141
+ +K V+ ++ LN++ E+ +K L + NIV+Y H +E+ +L+E
Sbjct: 50 VVAIKEVVYENDEELNDIMAEISLLKNLNHN-NIVKY-------HGFIRKSYELYILLEY 101
Query: 142 CPKKSLLDYMNNKLATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDD 201
C SL ++ +T L+E E + + +H +IHRDIK N+L+ D+
Sbjct: 102 CANGSLRRLISRS-STGLSENESKTYVTQTLLGLKYLH--GEGVIHRDIKAANILLSADN 158
Query: 202 NFKLCDFGSTSMCFPIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWA 261
KL DFG VST + + LT + T + +PE++ + SDIW+
Sbjct: 159 TVKLADFG--------VSTIVNSSALT----LAGTLNWMAPEILGNRGASTL---SDIWS 203
Query: 262 LGIFLYKLLFYTTPF----ELTGQFAILHSKYEIPQNGYSSKLINLIIIMLAENPSLRPN 317
LG + ++L P+ + +A+ + Y P + +S L + + +N RP
Sbjct: 204 LGATVVEMLTKNPPYHNLTDANIYYAVENDTY-YPPSSFSEPLKDFLSKCFVKNMYKRPT 262
Query: 318 IYQVMHHV 325
Q++ HV
Sbjct: 263 ADQLLKHV 270
>HsM7657627 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 970
Score = 69.7 bits (169), Expect = 2e-11
Identities = 75/288 (26%), Positives = 130/288 (45%), Gaps = 54/288 (18%)
Query: 48 LAEGGFANIYKVKFLELTNEMDAG-IDSKLL-KAGDIACLKRVIVPDENGLNELRNEVET 105
L +G FA +Y+ + + E+ ID K + KAG + ++NEV+
Sbjct: 18 LGKGSFAGVYRAESIHTGLEVAIKMIDKKAMYKAGMV--------------QRVKNEVKI 63
Query: 106 MKQLRGSPNIVQYY----DSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLTE 161
QL+ P+I++ Y DSN + L++E+C + Y+ N++ +E
Sbjct: 64 HCQLK-HPSILELYNYFEDSNY-----------VYLVLEMCHNGEMNRYLKNRVKP-FSE 110
Query: 162 AEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFG-STSMCFPIVST 220
E M+ + + +H ++HRD+ + N+L+ ++ N K+ DFG +T + P
Sbjct: 111 NEARHFMHQIITGMLYLH--SHGILHRDLTLSNLLLTRNMNIKIADFGLATQLKMP---- 164
Query: 221 HQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTPFELTG 280
H+ L TP Y SPE+ +SD+W+LG Y LL PF+
Sbjct: 165 HEKHYTLCG------TPNYISPEIATR---SAHGLESDVWSLGCMFYTLLIGRPPFDTDT 215
Query: 281 QFAILH----SKYEIPQNGYSSKLINLIIIMLAENPSLRPNIYQVMHH 324
L+ + YE+P S + +LI +L NP+ R ++ V+ H
Sbjct: 216 VKNTLNKVVLADYEMP-TFLSIEAKDLIHQLLRRNPADRLSLSSVLDH 262
>HsM4507279 [D] KOG0580 Serine/threonine protein kinase
Length = 402
Score = 69.7 bits (169), Expect = 2e-11
Identities = 80/299 (26%), Positives = 128/299 (42%), Gaps = 47/299 (15%)
Query: 32 NTQVVVGTHRCEILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVP 91
N + V EI L +G F N+Y + + SK + A + L + +
Sbjct: 122 NQKEAVALEDFEIGRPLGKGKFGNVYLAREKQ----------SKFILA--LKVLFKAQLE 169
Query: 92 DENGLNELRNEVETMKQLRGSPNIVQYYD--SNASRHPDGSPGFEILLLMELCPKKSLLD 149
++LR EVE LR PNI++ Y +A+R + L++E P ++
Sbjct: 170 KAGVEHQLRREVEIQSHLR-HPNILRLYGYFHDATR---------VYLILEYAPLGTV-- 217
Query: 150 YMNNKLATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFG 209
Y + +K E + ++NA++ H +IHRDIK EN+L+ K+ DFG
Sbjct: 218 YRELQKLSKFDEQRTANLYNRIANALSYCH--SKRVIHRDIKPENLLLGSAGELKIADFG 275
Query: 210 STSMCFPIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKL 269
S H A + + T Y PEMI+ +EK D+W+LG+ Y+
Sbjct: 276 --------WSVH---APSSRRTTLCGTLDYLPPEMIE---GRMHDEKVDLWSLGVLCYEF 321
Query: 270 LFYTTPFELT----GQFAILHSKYEIPQNGYSSKLINLIIIMLAENPSLRPNIYQVMHH 324
L PFE I ++ P + + +LI +L NPS RP + +V+ H
Sbjct: 322 LVGKPPFEANTYQETYKRISRVEFTFP-DFVTEGARDLISRLLKHNPSQRPMLREVLEH 379
>HsM4505103 [R] KOG0586 Serine/threonine protein kinase
Length = 713
Score = 69.7 bits (169), Expect = 2e-11
Identities = 77/318 (24%), Positives = 133/318 (41%), Gaps = 44/318 (13%)
Query: 9 RPNSVAHTAATSAMIPNSHLLSPNTQVVVGTHRCEILEHLAEGGFANIYKVKFLELTNEM 68
R + T+ + A NS + Q +G +R +L+ + +G FA + + + E+
Sbjct: 25 RQEVTSRTSRSGARCRNSIASCADEQPHIGNYR--LLKTIGKGNFAKVKLARHILTGREV 82
Query: 69 DAGIDSKLLKAGDIACLKRVIVPDENGLNELRNEVETMKQLRGSPNIVQYYDSNASRHPD 128
I K + L +L EV MK L PNIV+ ++ ++
Sbjct: 83 AIKIIDKTQL-------------NPTSLQKLFREVRIMKILN-HPNIVKLFEVIETQKT- 127
Query: 129 GSPGFEILLLMELCPKKSLLDYMNNKLATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHR 188
+ L+ME + DY+ ++ E E + +A+ H ++HR
Sbjct: 128 ------LYLIMEYASGGKVFDYL--VAHGRMKEKEARSKFRQIVSAVQYCHQ--KRIVHR 177
Query: 189 DIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLY 248
D+K EN+L+D D N K+ DFG ++ + V +P Y +PE+
Sbjct: 178 DLKAENLLLDADMNIKIADFGFSN----------EFTVGGKLDTFCGSPPYAAPELFQGK 227
Query: 249 RCLPINEKSDIWALGIFLYKLLFYTTPFELTG----QFAILHSKYEIPQNGYSSKLINLI 304
+ + D+W+LG+ LY L+ + PF+ + +L KY IP S+ NL+
Sbjct: 228 KY--DGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFY-MSTDCENLL 284
Query: 305 IIMLAENPSLRPNIYQVM 322
L NP R + Q+M
Sbjct: 285 KRFLVLNPIKRGTLEQIM 302
>Hs14042947 [T] KOG0583 Serine/threonine protein kinase
Length = 367
Score = 69.7 bits (169), Expect = 2e-11
Identities = 64/232 (27%), Positives = 114/232 (48%), Gaps = 25/232 (10%)
Query: 99 LRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATK 158
L E+E + L +I++ Y+ + H ++ ++MEL + LL+ + + A
Sbjct: 57 LPREIEILAMLNHC-SIIKTYEIFETSHG------KVYIVMELAVQGDLLELIKTRGA-- 107
Query: 159 LTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIV 218
L E E K + +S AI H L ++HRD+K +N+L+DKD N KL DF + C
Sbjct: 108 LHEDEARKKFHQLSLAIKYCHDLD--VVHRDLKCDNLLLDKDFNIKLSDFSFSKRCL--- 162
Query: 219 STHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEK-SDIWALGIFLYKLLFYTTPFE 277
D + + +P Y +PE++ + +P K DIW+LG+ LY ++ + P++
Sbjct: 163 --RDDSGRMALSKTFCGSPAYAAPEVL---QGIPYQPKVYDIWSLGVILYIMVCGSMPYD 217
Query: 278 LTGQFAILHSKYEIPQNGYSSKLI-----NLIIIMLAENPSLRPNIYQVMHH 324
+ +L + E N SK + +LI ML + + R +I +++ H
Sbjct: 218 DSNIKKMLRIQKEHRVNFPRSKHLTGECKDLIYHMLQPDVNRRLHIDEILSH 269
>At5g59700 [T] KOG1187 Serine/threonine protein kinase
Length = 829
Score = 69.7 bits (169), Expect = 2e-11
Identities = 68/276 (24%), Positives = 115/276 (41%), Gaps = 49/276 (17%)
Query: 1 MSKSDTISRPNSVAHTAATSAMIPNSHLLSPNTQVVVGTHRCEILEHLAEGGFANIYKVK 60
+S + T S N + S NS P V T+ + + GGF +YK +
Sbjct: 445 LSSNGTTSSSNGTTLASIAS----NSSYRIPLVAVKEATNSFDENRAIGVGGFGKVYKGE 500
Query: 61 FLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNELRNEVETMKQLRGSP--NIVQY 118
L G +KR + GL E R E+E + Q R +++ Y
Sbjct: 501 ----------------LHDGTKVAVKRANPKSQQGLAEFRTEIEMLSQFRHRHLVSLIGY 544
Query: 119 YDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLTEAEILKIMYDVSNAIAQM 178
D N E++L+ E +L ++ L+ + L+I + +
Sbjct: 545 CDENN----------EMILVYEYMENGTLKSHLYGSGLLSLSWKQRLEICIGSARGL--- 591
Query: 179 HYLPT----PLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTHQDIAVLTNNIYVH 234
HYL T P+IHRD+K N+L+D++ K+ DFG + I TH AV + +
Sbjct: 592 HYLHTGDAKPVIHRDVKSANILLDENLMAKVADFGLSKTGPEIDQTHVSTAV--KGSFGY 649
Query: 235 TTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLL 270
P+Y +R + EKSD+++ G+ ++++L
Sbjct: 650 LDPEY--------FRRQQLTEKSDVYSFGVVMFEVL 677
>At5g11015 [T] KOG1187 Serine/threonine protein kinase
Length = 402
Score = 69.7 bits (169), Expect = 2e-11
Identities = 75/316 (23%), Positives = 136/316 (42%), Gaps = 64/316 (20%)
Query: 48 LAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNELRNEVETMK 107
L +GGF +Y L N + A + K++ +E+ E ++EVE +
Sbjct: 116 LGQGGFGCVYSAT---LENNISAAV-------------KKLDCANEDAAKEFKSEVEILS 159
Query: 108 QLRGSPNIVQY--YDSNASRHPDGSPGFEILLLMELCPKKSLLDYMN-NKLATKLTEAEI 164
+L+ PNI+ Y +N + ++ EL P SL +++ + + +T
Sbjct: 160 KLQ-HPNIISLLGYSTNDTAR---------FIVYELMPNVSLESHLHGSSQGSAITWPMR 209
Query: 165 LKIMYDVSNAIAQMHYLPTP-LIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTHQD 223
+KI DV+ + +H P +IHRD+K N+L+D + N K+ DFG + P H+
Sbjct: 210 MKIALDVTRGLEYLHEHCHPAIIHRDLKSSNILLDSNFNAKISDFGLAVVDGPKNKNHK- 268
Query: 224 IAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTPFE------ 277
+ T Y +PE + + + EKSD++A G+ L +LL P E
Sbjct: 269 ---------LSGTVGYVAPEYLLNGQ---LTEKSDVYAFGVVLLELLLGKKPVEKLAPGE 316
Query: 278 ----LTGQFAILHSKYEIP-----------QNGYSSKLINLIIIMLAENPSLRPNIYQVM 322
+T L + ++P + ++ + I+ + PS RP I V+
Sbjct: 317 CQSIITWAMPYLTDRTKLPSVIDPAIKDTMDLKHLYQVAAVAILCVQPEPSYRPLITDVL 376
Query: 323 HHVCSILKCDVPFTDK 338
H + ++ ++ T K
Sbjct: 377 HSLIPLVPMELGGTLK 392
>At4g04740 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 520
Score = 69.7 bits (169), Expect = 2e-11
Identities = 83/287 (28%), Positives = 127/287 (43%), Gaps = 51/287 (17%)
Query: 60 KFLELTNEMDAG-----IDSKLLKAGDI-AC---LKRVIVPDENGLNELRNEVETMKQLR 110
KF L E+ G K + G+I AC LKR ++ E G +++ E++ M+ L
Sbjct: 67 KFYSLGRELGRGGLGITYMCKEIGTGNIYACKSILKRKLI-SELGREDVKTEIQIMQHLS 125
Query: 111 GSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLD-YMNNKLATKLTEAEILKIMY 169
G PN+V+ S RH + L+MELC L D + ++ A +K +
Sbjct: 126 GQPNVVEIKGSYEDRH-------SVHLVMELCAGGELFDRIIAQGHYSERAAAGTIKSIV 178
Query: 170 DVSNAIAQMHYLPTPLIHRDIKIENVLV-DKDDN--FKLCDFGSTSMCFPIVSTHQDIAV 226
DV Q+ +L +IHRD+K EN L K++N K+ DFG ++ +
Sbjct: 179 DV----VQICHL-NGVIHRDLKPENFLFSSKEENAMLKVTDFGLSAF------------I 221
Query: 227 LTNNIY--VHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTPFELTGQ--- 281
IY V +P Y +PE++ ++ DIW+ G+ LY LL PF +
Sbjct: 222 EEGKIYKDVVGSPYYVAPEVLR----QSYGKEIDIWSAGVILYILLCGVPPFWADNEEGV 277
Query: 282 -FAILHSKYEI---PQNGYSSKLINLIIIMLAENPSLRPNIYQVMHH 324
IL K + P S +L+ ML E+P R QV+ H
Sbjct: 278 FVEILKCKIDFVREPWPSISDSAKDLVEKMLTEDPKRRITAAQVLEH 324
>At3g46290 [T] KOG1187 Serine/threonine protein kinase
Length = 830
Score = 69.7 bits (169), Expect = 2e-11
Identities = 61/257 (23%), Positives = 112/257 (42%), Gaps = 45/257 (17%)
Query: 20 SAMIPNSHLLSPNTQVVVGTHRCEILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKA 79
+++ N++ P V T+ + ++ GGF +YK + L
Sbjct: 463 TSITTNANYRIPFAAVKDATNNFDESRNIGVGGFGKVYKGE----------------LND 506
Query: 80 GDIACLKRVIVPDENGLNELRNEVETMKQLRGSP--NIVQYYDSNASRHPDGSPGFEILL 137
G +KR + GL E R E+E + Q R +++ Y D N E++L
Sbjct: 507 GTKVAVKRGNPKSQQGLAEFRTEIEMLSQFRHRHLVSLIGYCDENN----------EMIL 556
Query: 138 LMELCPKKSLLDYMNNKLATKLTEAEILKIMYDVSNAIAQMHYLPT----PLIHRDIKIE 193
+ E ++ ++ LT + L+I + + HYL T P+IHRD+K
Sbjct: 557 IYEYMENGTVKSHLYGSGLPSLTWKQRLEICIGAARGL---HYLHTGDSKPVIHRDVKSA 613
Query: 194 NVLVDKDDNFKLCDFGSTSMCFPIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPI 253
N+L+D++ K+ DFG + + TH AV + + P+Y +R +
Sbjct: 614 NILLDENFMAKVADFGLSKTGPELDQTHVSTAV--KGSFGYLDPEY--------FRRQQL 663
Query: 254 NEKSDIWALGIFLYKLL 270
+KSD+++ G+ L+++L
Sbjct: 664 TDKSDVYSFGVVLFEVL 680
>At1g14370 [T] KOG1187 Serine/threonine protein kinase
Length = 426
Score = 69.7 bits (169), Expect = 2e-11
Identities = 77/297 (25%), Positives = 129/297 (42%), Gaps = 47/297 (15%)
Query: 48 LAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNELRNEVETMK 107
L EGGF ++K +++ T+ + + +G + +K++ G E EV +
Sbjct: 92 LGEGGFGCVFK-GWIDQTS-----LTASRPGSGIVVAVKQLKPEGFQGHKEWLTEVNYLG 145
Query: 108 QLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLTEAEILKI 167
QL PN+V A G LL+ E PK SL +++ + A LT A +K+
Sbjct: 146 QL-SHPNLVLLVGYCAE-------GENRLLVYEFMPKGSLENHLFRRGAQPLTWAIRMKV 197
Query: 168 MYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTHQDIAVL 227
+ + +H + +I+RD K N+L+D D N KL DFG +TH V+
Sbjct: 198 AVGAAKGLTFLHEAKSQVIYRDFKAANILLDADFNAKLSDFGLAKAGPTGDNTHVSTKVI 257
Query: 228 TNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFL------------------YKL 269
T Y +PE + R + KSD+++ G+ L Y L
Sbjct: 258 -------GTHGYAAPEYVATGR---LTAKSDVYSFGVVLLELISGRRAMDNSNGGNEYSL 307
Query: 270 LFYTTPF--ELTGQFAILHSKY--EIPQNGYSSKLINLIIIMLAENPSLRPNIYQVM 322
+ + TP+ + F I+ +K + PQ G + NL + L + LRP + +V+
Sbjct: 308 VDWATPYLGDKRKLFRIMDTKLGGQYPQKG-AFTAANLALQCLNPDAKLRPKMSEVL 363
>Hs7706601 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 800
Score = 69.3 bits (168), Expect = 2e-11
Identities = 64/239 (26%), Positives = 107/239 (43%), Gaps = 52/239 (21%)
Query: 43 EILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNELRNE 102
+ E+ G F ++Y+ K++ E+ KLLK + E
Sbjct: 17 QFFENCGGGSFGSVYRAKWISQDKEVAV---KKLLK--------------------IEKE 53
Query: 103 VETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLTEA 162
E + L NI+Q+Y P + I+ E SL DY+N+ + ++
Sbjct: 54 AEILSVL-SHRNIIQFYGVILE-----PPNYGIVT--EYASLGSLYDYINSNRSEEMDMD 105
Query: 163 EILKIMYDVSNAIAQMHYL----PTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIV 218
I+ DV+ MHYL P +IHRD+K NV++ D K+CDFG++ F
Sbjct: 106 HIMTWATDVAKG---MHYLHMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASR--FHNH 160
Query: 219 STHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTPFE 277
+TH + V T P + +PE+I + LP++E D ++ G+ L+++L PF+
Sbjct: 161 TTHMSL--------VGTFP-WMAPEVI---QSLPVSETCDTYSYGVVLWEMLTREVPFK 207
>Hs19526767 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 455
Score = 69.3 bits (168), Expect = 2e-11
Identities = 64/239 (26%), Positives = 107/239 (43%), Gaps = 52/239 (21%)
Query: 43 EILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNELRNE 102
+ E+ G F ++Y+ K++ E+ KLLK + E
Sbjct: 17 QFFENCGGGSFGSVYRAKWISQDKEVAV---KKLLK--------------------IEKE 53
Query: 103 VETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLTEA 162
E + L NI+Q+Y P + I+ E SL DY+N+ + ++
Sbjct: 54 AEILSVL-SHRNIIQFYGVILE-----PPNYGIVT--EYASLGSLYDYINSNRSEEMDMD 105
Query: 163 EILKIMYDVSNAIAQMHYL----PTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIV 218
I+ DV+ MHYL P +IHRD+K NV++ D K+CDFG++ F
Sbjct: 106 HIMTWATDVAKG---MHYLHMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASR--FHNH 160
Query: 219 STHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTPFE 277
+TH + V T P + +PE+I + LP++E D ++ G+ L+++L PF+
Sbjct: 161 TTHMSL--------VGTFP-WMAPEVI---QSLPVSETCDTYSYGVVLWEMLTREVPFK 207
>At1g54510 [R] KOG0589 Serine/threonine protein kinase
Length = 612
Score = 69.3 bits (168), Expect = 2e-11
Identities = 54/228 (23%), Positives = 104/228 (44%), Gaps = 28/228 (12%)
Query: 102 EVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLTE 161
E+E + ++R P IV+Y DS + + +++ C + + E
Sbjct: 51 EMELISKMR-HPFIVEYKDSWVEK------ACYVCIVIGYCEGGDMAQAIKKSNGVHFQE 103
Query: 162 AEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTH 221
++ K + + + +H ++HRD+K N+ + K+ + +L DFG + T
Sbjct: 104 EKLCKWLVQLLMGLEYLH--SNHILHRDVKCSNIFLTKEQDIRLGDFGLAK-----ILTS 156
Query: 222 QDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTPFELTGQ 281
D LT+++ TP Y PE++ +P KSDIW+LG +Y++ + F+
Sbjct: 157 DD---LTSSVV--GTPSYMCPELL---ADIPYGSKSDIWSLGCCIYEMAYLKPAFKAFDM 208
Query: 282 FAILHSKYE-----IPQNGYSSKLINLIIIMLAENPSLRPNIYQVMHH 324
A+++ + +P YS L+ ML +NP +RP+ ++ H
Sbjct: 209 QALINKINKTIVSPLPAK-YSGPFRGLVKSMLRKNPEVRPSASDLLRH 255
>Hs20428779_1 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 357
Score = 69.3 bits (168), Expect = 2e-11
Identities = 65/235 (27%), Positives = 107/235 (44%), Gaps = 33/235 (14%)
Query: 39 THRCEILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNE 98
T EI+E + +G + +YKV TN+ D G +A +K ++ P + E
Sbjct: 24 TDTWEIIETIGKGTYGKVYKV-----TNKRD----------GSLAAVK-ILDPVSDMDEE 67
Query: 99 LRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKL--A 156
+ E ++ L PN+V++Y D G ++ L++ELC S+ + + L
Sbjct: 68 IEAEYNILQFLPNHPNVVKFY--GMFYKADHCVGGQLWLVLELCNGGSVTELVKGLLRCG 125
Query: 157 TKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFP 216
+L EA I I+Y + +H +IHRD+K N+L+ + KL DFG
Sbjct: 126 QRLDEAMISYILYGALLGLQHLHN--NRIIHRDVKGNNILLTTEGGVKLVDFG------- 176
Query: 217 IVSTHQDIAVLTNNIYVHTTPQYRSPEMI--DLYRCLPINEKSDIWALGIFLYKL 269
VS L N V TP + +PE+I + + + D+W+LGI +L
Sbjct: 177 -VSAQLTSTRLRRNTSV-GTPFWMAPEVIACEQQYDSSYDARCDVWSLGITAIEL 229
>SPAC644.06c [D] KOG0588 Serine/threonine protein kinase
Length = 593
Score = 68.9 bits (167), Expect = 3e-11
Identities = 74/260 (28%), Positives = 115/260 (43%), Gaps = 42/260 (16%)
Query: 74 SKLLKAGDIACLKRVIVPDENGLNELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGF 133
+K K GD+A +K I+P + E+ M+ LR PNI++ YD
Sbjct: 29 AKHAKTGDLAAIK--IIPIRYA--SIGMEILMMRLLR-HPNILRLYDVWTDHQ------- 76
Query: 134 EILLLMELCPKKSLLDYMNNKLATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIE 193
+ L +E P L Y+ L+E E + + +A+A H HRD+K+E
Sbjct: 77 HMYLALEYVPDGELFHYIRKH--GPLSEREAAHYLSQILDAVAHCHRFR--FRHRDLKLE 132
Query: 194 NVLVD-KDDNFKLCDFGSTSMCFPIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDL--YRC 250
N+L+ + K+ DFG + + + + L N + Y +PE++ YR
Sbjct: 133 NILIKVNEQQIKIADFG-------MATVEPNDSCLENYC---GSLHYLAPEIVSHKPYRG 182
Query: 251 LPINEKSDIWALGIFLYKLLFYTTPFELTGQFA------ILHSKYEIPQNGYSSKLINLI 304
P +D+W+ G+ LY LL PF GQ I H Y++P + SS +L+
Sbjct: 183 AP----ADVWSCGVILYSLLSNKLPF--GGQNTDVIYNKIRHGAYDLP-SSISSAAQDLL 235
Query: 305 IIMLAENPSLRPNIYQVMHH 324
ML NPS R I +V H
Sbjct: 236 HRMLDVNPSTRITIPEVFSH 255
>Hs21361433 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 970
Score = 68.9 bits (167), Expect = 3e-11
Identities = 75/288 (26%), Positives = 130/288 (45%), Gaps = 54/288 (18%)
Query: 48 LAEGGFANIYKVKFLELTNEMDAG-IDSKLL-KAGDIACLKRVIVPDENGLNELRNEVET 105
L +G FA +Y+ + + E+ ID K + KAG + ++NEV+
Sbjct: 18 LGKGSFAGVYRAESIHSGLEVAIKMIDKKAMYKAGMV--------------QRVQNEVKI 63
Query: 106 MKQLRGSPNIVQYY----DSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLTE 161
QL+ P+I++ Y DSN + L++E+C + Y+ N++ +E
Sbjct: 64 HCQLK-HPSILELYNYFEDSNY-----------VYLVLEMCHNGEMNRYLKNRVKP-FSE 110
Query: 162 AEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFG-STSMCFPIVST 220
E M+ + + +H ++HRD+ + N+L+ ++ N K+ DFG +T + P
Sbjct: 111 NEARHFMHQIITGMLYLH--SHGILHRDLTLSNLLLTRNMNIKIADFGLATQLKMP---- 164
Query: 221 HQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTPFELTG 280
H+ L TP Y SPE+ +SD+W+LG Y LL PF+
Sbjct: 165 HEKHYTLCG------TPNYISPEIATR---SAHGLESDVWSLGCMFYTLLIGRPPFDTDT 215
Query: 281 QFAILH----SKYEIPQNGYSSKLINLIIIMLAENPSLRPNIYQVMHH 324
L+ + YE+P S + +LI +L NP+ R ++ V+ H
Sbjct: 216 VKNTLNKVVLADYEMP-TFLSIEAKDLIHQLLRRNPADRLSLSSVLDH 262
>CE24994 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 536
Score = 68.9 bits (167), Expect = 3e-11
Identities = 53/179 (29%), Positives = 89/179 (49%), Gaps = 24/179 (13%)
Query: 99 LRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATK 158
L E + M LR PNI++ Y S P G ++ME S+ D + ++
Sbjct: 94 LIREAKVMWDLRNHPNIIKIYGLYKS--PRNGQG----VVMEYMDCGSMADLLYDRTHIN 147
Query: 159 LTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLV-DKDDNFKLCDFGSTSMCFPI 217
T + M+ +S+A+ H +HRD+K++N+L+ D+ KLCDFG+
Sbjct: 148 YTIDHVASWMFQLSSAVDFFH--SNSQVHRDLKLQNMLLSDRYRTMKLCDFGT------F 199
Query: 218 VSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTPF 276
S HQ +T+N TP +PE+ +RC N KSDI+++GI +++++ P+
Sbjct: 200 TSMHQS---MTSN---RGTPITMAPEV---FRCEQYNMKSDIYSIGIIMWQIIARNHPY 249
>At2g23200 [T] KOG1187 Serine/threonine protein kinase
Length = 834
Score = 68.9 bits (167), Expect = 3e-11
Identities = 65/270 (24%), Positives = 123/270 (45%), Gaps = 47/270 (17%)
Query: 8 SRPNSVAHTAATSAMIPNSHL--LSPNTQVVVGTHRCEILEHLAEGGFANIYKVKFLELT 65
+RP S H + + N HL P T ++ T+ + + +GGF +YK
Sbjct: 456 NRPISQYHNSP----LRNLHLGLTIPFTDILSATNNFDEQLLIGKGGFGYVYKA------ 505
Query: 66 NEMDAGIDSKLLKAGDIACLKRVIVPDENGLNELRNEVETMKQLRGSP--NIVQYYDSNA 123
+L G A +KR G+ E + E++ + ++R ++ Y + N+
Sbjct: 506 ----------ILPDGTKAAIKRGKTGSGQGILEFQTEIQVLSRIRHRHLVSLTGYCEENS 555
Query: 124 SRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLTEAEILKIMYDVSNAIAQMHYLPT 183
E++L+ E K +L +++ LT + L+I + + +H +
Sbjct: 556 ----------EMILVYEFMEKGTLKEHLYGSNLPSLTWKQRLEICIGAARGLDYLHSSGS 605
Query: 184 P--LIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTHQDIAVLTNNIYVHTTPQYRS 241
+IHRD+K N+L+D+ + K+ DFG + + +QD + ++ NI T Y
Sbjct: 606 EGAIIHRDVKSTNILLDEHNIAKVADFGLSKI------HNQDESNISINI--KGTFGYLD 657
Query: 242 PEMIDLYRCLPINEKSDIWALGIFLYKLLF 271
PE + ++ + EKSD++A G+ L ++LF
Sbjct: 658 PEYLQTHK---LTEKSDVYAFGVVLLEVLF 684
>7302464 [R] KOG0586 Serine/threonine protein kinase
Length = 739
Score = 68.9 bits (167), Expect = 3e-11
Identities = 79/326 (24%), Positives = 140/326 (42%), Gaps = 52/326 (15%)
Query: 8 SRPNSVAHTAATSAMIPNSHLLSPN------TQVVVGTHRCEILEHLAEGGFANIYKVKF 61
+ P+++ +++ PN + S T+ +G ++ +++ + +G FA + K
Sbjct: 113 AHPSAIKQRTSSAKGSPNMQMRSSAPMRWRATEEHIGKYK--LIKTIGKGNFAKVKLAKH 170
Query: 62 LELTNEMDAGI-DSKLLKAGDIACLKRVIVPDENGLNELRNEVETMKQLRGSPNIVQYYD 120
L E+ I D L G L +L EV MK L PNIV+ +
Sbjct: 171 LPTGKEVAIKIIDKTQLNPGS--------------LQKLFREVRIMKML-DHPNIVKLFQ 215
Query: 121 SNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLTEAEILKIMYDVSNAIAQMHY 180
+ + L+ME + DY+ L ++ E E + +A+ H
Sbjct: 216 VIETEKT-------LYLIMEYASGGEVFDYL--VLHGRMKEKEARVKFRQIVSAVQYCHQ 266
Query: 181 LPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTHQDIAVLTNNIYVHTTPQYR 240
+IHRD+K EN+L+D + N K+ DFG ++ P + D +P Y
Sbjct: 267 --KRIIHRDLKAENLLLDSELNIKIADFGFSNEFTP--GSKLDTFC--------GSPPYA 314
Query: 241 SPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTPFELTG----QFAILHSKYEIPQNGY 296
+PE+ + + D+W+LG+ LY L+ + PF+ + + +L KY IP
Sbjct: 315 APELFQGKKY--DGPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFY-M 371
Query: 297 SSKLINLIIIMLAENPSLRPNIYQVM 322
S+ NL+ L NP+ R ++ +M
Sbjct: 372 STDCENLLRKFLVLNPAKRASLETIM 397
>Hs4507275 [D] KOG0580 Serine/threonine protein kinase
Length = 403
Score = 68.6 bits (166), Expect = 4e-11
Identities = 78/288 (27%), Positives = 126/288 (43%), Gaps = 47/288 (16%)
Query: 43 EILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNELRNE 102
EI L +G F N+Y + + SK + A + L + + ++LR E
Sbjct: 134 EIGRPLGKGKFGNVYLAREKQ----------SKFILA--LKVLFKAQLEKAGVEHQLRRE 181
Query: 103 VETMKQLRGSPNIVQYYD--SNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLT 160
VE LR PNI++ Y +A+R + L++E P ++ Y + +K
Sbjct: 182 VEIQSHLR-HPNILRLYGYFHDATR---------VYLILEYAPLGTV--YRELQKLSKFD 229
Query: 161 EAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVST 220
E + +++NA++ H +IHRDIK EN+L+ K+ DFG S
Sbjct: 230 EQRTATYITELANALSYCH--SKRVIHRDIKPENLLLGSAGELKIADFG--------WSV 279
Query: 221 HQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTPFELT- 279
H A + + T Y PEMI+ +EK D+W+LG+ Y+ L PFE
Sbjct: 280 H---APSSRRTTLCGTLDYLPPEMIE---GRMHDEKVDLWSLGVLCYEFLVGKPPFEANT 333
Query: 280 ---GQFAILHSKYEIPQNGYSSKLINLIIIMLAENPSLRPNIYQVMHH 324
I ++ P + + +LI +L NPS RP + +V+ H
Sbjct: 334 YQETYKRISRVEFTFP-DFVTEGARDLISRLLKHNPSQRPMLREVLEH 380
>Hs20547806 [R] KOG0589 Serine/threonine protein kinase
Length = 489
Score = 68.6 bits (166), Expect = 4e-11
Identities = 75/281 (26%), Positives = 121/281 (42%), Gaps = 46/281 (16%)
Query: 44 ILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDE-NGLNELRNE 102
+L + EG F V+ E +N+M A +K + +P + R E
Sbjct: 6 VLRMIGEGSFGRALLVQH-ESSNQMFA--------------MKEIRLPKSFSNTQNSRKE 50
Query: 103 VETMKQLRGSPNIVQYYDS-NASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLTE 161
+ +++ PNIV + +S A H + ++ME C L+ + + E
Sbjct: 51 AVLLAKMK-HPNIVAFKESFEAEGH--------LYIVMEYCDGGDLMQKIKQQKGKLFPE 101
Query: 162 AEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTH 221
IL + + +H ++HRDIK +N+ + ++ KL DFGS + +S
Sbjct: 102 DMILNWFTQMCLGVNHIH--KKRVLHRDIKSKNIFLTQNGKVKLGDFGSARL----LSNP 155
Query: 222 QDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTPFELTGQ 281
A YV T P Y PE ++ LP N KSDIW+LG LY+L PF+
Sbjct: 156 MAFACT----YVGT-PYYVPPE---IWENLPYNNKSDIWSLGCILYELCTLKHPFQANSW 207
Query: 282 FAILHSKYE-----IPQNGYSSKLINLIIIMLAENPSLRPN 317
++ + +P + YS +L L+ M NPS RP+
Sbjct: 208 KNLILKVCQGCISPLPSH-YSYELQFLVKQMFKRNPSHRPS 247
>At5g35410 [T] KOG0583 Serine/threonine protein kinase
Length = 446
Score = 68.6 bits (166), Expect = 4e-11
Identities = 76/279 (27%), Positives = 132/279 (47%), Gaps = 38/279 (13%)
Query: 43 EILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNELRNE 102
E+ + EG FA KVKF T+ D + K++ I LK +V ++++ E
Sbjct: 12 EVGRTIGEGTFA---KVKFARNTDTGD-NVAIKIMAKSTI--LKNRMV------DQIKRE 59
Query: 103 VETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLTEA 162
+ MK +R PNIV+ Y+ AS +I +++E L D + +K +L E+
Sbjct: 60 ISIMKIVR-HPNIVRLYEVLASPS-------KIYIVLEFVTGGELFDRIVHK--GRLEES 109
Query: 163 EILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTHQ 222
E K + +A+A H + HRD+K EN+L+D + N K+ DFG +++ +
Sbjct: 110 ESRKYFQQLVDAVAHCHC--KGVYHRDLKPENLLLDTNGNLKVSDFGLSAL------PQE 161
Query: 223 DIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTPF---ELT 279
+ +L TP Y +PE++ +DIW+ G+ L+ +L PF +L
Sbjct: 162 GVELLRTTC---GTPNYVAPEVLSGQGY--DGSAADIWSCGVILFVILAGYLPFSETDLP 216
Query: 280 GQFAILHSKYEIPQNGYSSKLINLIIIMLAENPSLRPNI 318
G + +++ +S+++ LI +L NP R I
Sbjct: 217 GLYRKINAAEFSCPPWFSAEVKFLIHRILDPNPKTRIQI 255
>At4g18700 [T] KOG0583 Serine/threonine protein kinase
Length = 489
Score = 68.6 bits (166), Expect = 4e-11
Identities = 85/292 (29%), Positives = 136/292 (46%), Gaps = 47/292 (16%)
Query: 41 RCEILEHLAEGGFANIYKVKFLELTNEMDA--GIDS-KLLKAGDIACLKRVIVPDENGLN 97
R E+ + L G FA +Y + ++ TNE A ID K+LK G IA +KR
Sbjct: 25 RYEMGKLLGHGTFAKVYLARNVK-TNESVAIKVIDKEKVLKGGLIAHIKR---------- 73
Query: 98 ELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLAT 157
E+ ++++R PNIVQ ++ A++ +I +ME L NK+A
Sbjct: 74 ----EISILRRVR-HPNIVQLFEVMATKA-------KIYFVMEYVRGGELF----NKVAK 117
Query: 158 -KLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFP 216
+L E K + +A+ H + HRD+K EN+L+D++ N K+ DFG +++
Sbjct: 118 GRLKEEVARKYFQQLISAVTFCH--ARGVYHRDLKPENLLLDENGNLKVSDFGLSAVSDQ 175
Query: 217 IVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTPF 276
I QD T TP Y +PE+ L R K DIW+ G+ L+ L+ PF
Sbjct: 176 I---RQDGLFHT----FCGTPAYVAPEV--LARKGYDAAKVDIWSCGVILFVLMAGYLPF 226
Query: 277 ELTGQFA----ILHSKYEIPQNGYSSKLINLIIIMLAENPSLRPNIYQVMHH 324
A I ++ P+ +S++L L+ +L NP R ++M +
Sbjct: 227 HDRNVMAMYKKIYRGEFRCPR-WFSTELTRLLSKLLETNPEKRFTFPEIMEN 277
>At3g15220 [T] KOG0201 Serine/threonine protein kinase
Length = 690
Score = 68.6 bits (166), Expect = 4e-11
Identities = 66/284 (23%), Positives = 125/284 (43%), Gaps = 41/284 (14%)
Query: 45 LEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNELRNEVE 104
+E + G F ++YK +L E+ +K D+ E+ + +++ E+
Sbjct: 18 IELIGRGSFGDVYKAFDKDLNKEV-------AIKVIDLE-------ESEDEIEDIQKEIS 63
Query: 105 TMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLTEAEI 164
+ Q R P I +YY S + ++ ++ME S+ D + + L E I
Sbjct: 64 VLSQCR-CPYITEYYGSYLHQT-------KLWIIMEYMAGGSVADLLQSN--NPLDETSI 113
Query: 165 LKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTHQDI 224
I D+ +A+ +H IHRDIK N+L+ ++ + K+ DFG ++ +S +
Sbjct: 114 ACITRDLLHAVEYLHN--EGKIHRDIKAANILLSENGDVKVADFGVSAQLTRTISRRKTF 171
Query: 225 AVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTPF-ELTGQFA 283
TP + +PE+I NEK+DIW+LGI + ++ P +L
Sbjct: 172 V---------GTPFWMAPEVIQ--NSEGYNEKADIWSLGITVIEMAKGEPPLADLHPMRV 220
Query: 284 ILHSKYEIP---QNGYSSKLINLIIIMLAENPSLRPNIYQVMHH 324
+ E P +S ++ + + L + P+ RP+ +++ H
Sbjct: 221 LFIIPRETPPQLDEHFSRQVKEFVSLCLKKAPAERPSAKELIKH 264
>Hs9845489 [R] KOG0586 Serine/threonine protein kinase
Length = 691
Score = 68.2 bits (165), Expect = 5e-11
Identities = 75/300 (25%), Positives = 131/300 (43%), Gaps = 50/300 (16%)
Query: 30 SPNTQVVVGTHRCEILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVI 89
S + Q +G +R +L+ + +G FA + + + E+ I K
Sbjct: 10 SADEQPHIGNYR--LLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQL----------- 56
Query: 90 VPDENGLNELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLD 149
+ + L +L EV MK L PNIV+ ++ + + L+ME + D
Sbjct: 57 --NSSSLQKLFREVRIMKVLN-HPNIVKLFEVIETEKT-------LYLVMEYASGGEVFD 106
Query: 150 YM--NNKLATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCD 207
Y+ + ++ K A+ +I+ +A+ H ++HRD+K EN+L+D D N K+ D
Sbjct: 107 YLVAHGRMKEKEARAKFRQIV----SAVQYCHQ--KFIVHRDLKAENLLLDADMNIKIAD 160
Query: 208 FGSTSMCFPIVSTHQDIAVLTNNIYVHT-TPQYRSPEMIDLYRCLPINEKSDIWALGIFL 266
FG ++ N + +P Y +PE+ + + D+W+LG+ L
Sbjct: 161 FGFSNE-----------FTFGNKLDTFCGSPPYAAPELFQGKKY--DGPEVDVWSLGVIL 207
Query: 267 YKLLFYTTPFELTG----QFAILHSKYEIPQNGYSSKLINLIIIMLAENPSLRPNIYQVM 322
Y L+ + PF+ + +L KY IP S+ NL+ L NPS R + Q+M
Sbjct: 208 YTLVSGSLPFDGQNLKELRERVLRGKYRIPFY-MSTDCENLLKKFLILNPSKRGTLEQIM 266
>Hs9845487 [R] KOG0586 Serine/threonine protein kinase
Length = 745
Score = 68.2 bits (165), Expect = 5e-11
Identities = 75/300 (25%), Positives = 131/300 (43%), Gaps = 50/300 (16%)
Query: 30 SPNTQVVVGTHRCEILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVI 89
S + Q +G +R +L+ + +G FA + + + E+ I K
Sbjct: 10 SADEQPHIGNYR--LLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQL----------- 56
Query: 90 VPDENGLNELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLD 149
+ + L +L EV MK L PNIV+ ++ + + L+ME + D
Sbjct: 57 --NSSSLQKLFREVRIMKVLN-HPNIVKLFEVIETEKT-------LYLVMEYASGGEVFD 106
Query: 150 YM--NNKLATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCD 207
Y+ + ++ K A+ +I+ +A+ H ++HRD+K EN+L+D D N K+ D
Sbjct: 107 YLVAHGRMKEKEARAKFRQIV----SAVQYCHQ--KFIVHRDLKAENLLLDADMNIKIAD 160
Query: 208 FGSTSMCFPIVSTHQDIAVLTNNIYVHT-TPQYRSPEMIDLYRCLPINEKSDIWALGIFL 266
FG ++ N + +P Y +PE+ + + D+W+LG+ L
Sbjct: 161 FGFSNE-----------FTFGNKLDTFCGSPPYAAPELFQGKKY--DGPEVDVWSLGVIL 207
Query: 267 YKLLFYTTPFELTG----QFAILHSKYEIPQNGYSSKLINLIIIMLAENPSLRPNIYQVM 322
Y L+ + PF+ + +L KY IP S+ NL+ L NPS R + Q+M
Sbjct: 208 YTLVSGSLPFDGQNLKELRERVLRGKYRIPFY-MSTDCENLLKKFLILNPSKRGTLEQIM 266
>Hs22062450 [R] KOG0586 Serine/threonine protein kinase
Length = 787
Score = 68.2 bits (165), Expect = 5e-11
Identities = 75/300 (25%), Positives = 131/300 (43%), Gaps = 50/300 (16%)
Query: 30 SPNTQVVVGTHRCEILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVI 89
S + Q +G +R +L+ + +G FA + + + E+ I K
Sbjct: 43 SADEQPHIGNYR--LLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQL----------- 89
Query: 90 VPDENGLNELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLD 149
+ + L +L EV MK L PNIV+ ++ + + L+ME + D
Sbjct: 90 --NSSSLQKLFREVRIMKVLN-HPNIVKLFEVIETEKT-------LYLVMEYASGGEVFD 139
Query: 150 YM--NNKLATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCD 207
Y+ + ++ K A+ +I+ +A+ H ++HRD+K EN+L+D D N K+ D
Sbjct: 140 YLVAHGRMKEKEARAKFRQIV----SAVQYCHQ--KFIVHRDLKAENLLLDADMNIKIAD 193
Query: 208 FGSTSMCFPIVSTHQDIAVLTNNIYVHT-TPQYRSPEMIDLYRCLPINEKSDIWALGIFL 266
FG ++ N + +P Y +PE+ + + D+W+LG+ L
Sbjct: 194 FGFSNE-----------FTFGNKLDTFCGSPPYAAPELFQGKKY--DGPEVDVWSLGVIL 240
Query: 267 YKLLFYTTPFELTG----QFAILHSKYEIPQNGYSSKLINLIIIMLAENPSLRPNIYQVM 322
Y L+ + PF+ + +L KY IP S+ NL+ L NPS R + Q+M
Sbjct: 241 YTLVSGSLPFDGQNLKELRERVLRGKYRIPFY-MSTDCENLLKKFLILNPSKRGTLEQIM 299
>CE21025 [D] KOG0580 Serine/threonine protein kinase
Length = 326
Score = 68.2 bits (165), Expect = 5e-11
Identities = 67/234 (28%), Positives = 106/234 (44%), Gaps = 33/234 (14%)
Query: 97 NELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLA 156
++L+ E+E LR PNI+ Y H D + ++++ + L + + ++
Sbjct: 87 HQLKREIEIQYHLR-HPNILTLY---GYFHDDK----RVFVILDYASRGELFNVLQSQPG 138
Query: 157 TKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFP 216
K+ E + + ++NA+ H +IHRDIK EN+L+D N KL DFG +
Sbjct: 139 HKVNEVIAGRFVRQLANALHYCH--SKGVIHRDIKPENLLLDSKLNLKLADFG-----WS 191
Query: 217 IVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTPF 276
+V+ H L T Y +PEM+ P + DIWA+GI L+++L PF
Sbjct: 192 VVADHSKRHTLCG------TMDYLAPEMVSNQ---PHDFNVDIWAIGILLFEMLVGYAPF 242
Query: 277 -ELTGQ---FAILHSKYEIPQ--NGYSSKLINLIIIMLAENPSLRPNIYQVMHH 324
TG I K IP ++ LIN II + P R + +M H
Sbjct: 243 ANQTGDKLIARIKECKIYIPSVVTDGAASLINAII---KKEPQERLPLVDIMAH 293
>At5g07070 [T] KOG0583 Serine/threonine protein kinase
Length = 456
Score = 68.2 bits (165), Expect = 5e-11
Identities = 75/243 (30%), Positives = 115/243 (46%), Gaps = 38/243 (15%)
Query: 39 THRCEILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNE 98
T R E+ L +G FA +Y + TNE S +K D + RV GL++
Sbjct: 9 TERYEVGRLLGQGTFAKVYFGRSNH-TNE------SVAIKMIDKDKVMRV------GLSQ 55
Query: 99 -LRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLAT 157
++ E+ M+ + PN+V+ Y+ A++ I ++E C L NK+A
Sbjct: 56 QIKREISVMR-IAKHPNVVELYEVMATKS-------RIYFVIEYCKGGELF----NKVAK 103
Query: 158 -KLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFP 216
KL E K Y + +A+ H + HRDIK EN+L+D +DN K+ DFG +++
Sbjct: 104 GKLKEDVAWKYFYQLISAVDFCH--SRGVYHRDIKPENLLLDDNDNLKVSDFGLSALA-- 159
Query: 217 IVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTPF 276
QD + T TP Y +PE+I+ R K+DIW+ G+ L+ LL PF
Sbjct: 160 -DCKRQDGLLHT----TCGTPAYVAPEVIN--RKGYEGTKADIWSCGVVLFVLLAGYLPF 212
Query: 277 ELT 279
T
Sbjct: 213 HDT 215
>YOL100w [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 1081
Score = 67.8 bits (164), Expect = 6e-11
Identities = 61/234 (26%), Positives = 104/234 (44%), Gaps = 31/234 (13%)
Query: 102 EVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLTE 161
E +++L SP++V+ + S D S + L+E P L M K L E
Sbjct: 227 EKTALQKLNNSPSVVRLF----STFQDES---SLYFLLEYAPNGDFLSLM--KKYGSLDE 277
Query: 162 AEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFP----I 217
+ +AI +H +IHRDIK EN+L+D + KL DFG+ + P +
Sbjct: 278 TCARYYAAQIIDAIDYLH--SNGIIHRDIKPENILLDGEMKIKLTDFGTAKLLNPTNNSV 335
Query: 218 VSTHQDIAVLTNNIYVHTTPQYRSPEMID----LYRCLPINEKSDIWALGIFLYKLLFYT 273
D++ + + T +Y SPE+++ YRC DIWA G L++++
Sbjct: 336 SKPEYDLSTRSKSFV--GTAEYVSPELLNDSFTDYRC-------DIWAFGCILFQMIAGK 386
Query: 274 TPFELTGQFAILHSKYEIP---QNGYSSKLINLIIIMLAENPSLRPNIYQVMHH 324
PF+ T ++ ++ G+ + +L+ +L +N R I Q+ H
Sbjct: 387 PPFKATNEYLTFQKVMKVQYAFTPGFPLIIRDLVKKILVKNLDRRLTISQIKEH 440
>Hs22035600 [T] KOG0576 Mitogen-activated protein kinase kinase kinase kinase
(MAP4K) germinal center kinase family
Length = 820
Score = 67.8 bits (164), Expect = 6e-11
Identities = 73/295 (24%), Positives = 130/295 (43%), Gaps = 50/295 (16%)
Query: 41 RCEILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNELR 100
R E+L+ + G + ++YK + +T+E+ A +K V + + ++ L+
Sbjct: 15 RFELLQRVGAGTYGDVYKARDT-VTSEL--------------AAVKIVKLDPGDDISSLQ 59
Query: 101 NEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLT 160
E+ +++ R PN+V Y S + + ME C SL + + AT
Sbjct: 60 QEITILRECR-HPNVVAYIGSYLRND-------RLWICMEFCGGGSLQEIYH---ATGPL 108
Query: 161 EAEILKIMYDVSNAIAQMHYLPTP-LIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVS 219
E +I Y A+ +H+L + IHRDIK N+L+ + KL DFG VS
Sbjct: 109 EER--QIAYVCREALKGLHHLHSQGKIHRDIKGANLLLTLQGDVKLADFG--------VS 158
Query: 220 THQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKL------LFYT 273
+V ++ T P + +PE+ + R NE D+WALGI +L LF+
Sbjct: 159 GELTASVAKRRSFIGT-PYWMAPEVAAVERKGGYNELCDVWALGITAIELGELQPPLFHL 217
Query: 274 TPFELTGQFAILHSKYEIP----QNGYSSKLINLIIIMLAENPSLRPNIYQVMHH 324
P + + S ++ P + ++ + + + L +NP RP +++ H
Sbjct: 218 HP--MRALMLMSKSSFQPPKLRDKTRWTQNFHHFLKLALTKNPKKRPTAEKLLQH 270
>Hs14770402 [R] KOG0586 Serine/threonine protein kinase
Length = 926
Score = 67.8 bits (164), Expect = 6e-11
Identities = 62/246 (25%), Positives = 113/246 (45%), Gaps = 29/246 (11%)
Query: 92 DENGLNELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYM 151
D L ++ EV+ MK L P+I++ Y ++ + L+ E + DY+
Sbjct: 57 DAVNLEKIYREVQIMKML-DHPHIIKLYQVMETKSM-------LYLVTEYAKNGEIFDYL 108
Query: 152 NNKLATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGST 211
N +L E+E + + + +A+ H ++HRD+K EN+L+D + N K+ DFG
Sbjct: 109 ANH--GRLNESEARRKFWQILSAVDYCH--GRKIVHRDLKAENLLLDNNMNIKIADFGFG 164
Query: 212 SMCFPIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLF 271
+ + + +A +P Y +PE+ + + + DIW++G+ LY L+
Sbjct: 165 N----FFKSGELLATWCG------SPPYAAPEVFEGQQY--EGPQLDIWSMGVVLYVLVC 212
Query: 272 YTTPFELTG----QFAILHSKYEIPQNGYSSKLINLIIIMLAENPSLRPNIYQVMHHVCS 327
PF+ + +L ++ IP S +LI ML +PS R I Q+ H
Sbjct: 213 GALPFDGPTLPILRQRVLEGRFRIPY-FMSEDCEHLIRRMLVLDPSKRLTIAQIKEHKWM 271
Query: 328 ILKCDV 333
+++ V
Sbjct: 272 LIEVPV 277
>CE21615 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 378
Score = 67.8 bits (164), Expect = 6e-11
Identities = 66/253 (26%), Positives = 115/253 (45%), Gaps = 37/253 (14%)
Query: 81 DIACLKRVIVPDENGLNELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLME 140
D+ +KR+ + L E++ MKQ R PN+V Y +S D + ++M+
Sbjct: 132 DVVAVKRMAFKTQPKKEMLLTEIKVMKQYR-HPNLVNYIESYLVDADD------LWVVMD 184
Query: 141 LCPKKSLLDYMNNKLATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKD 200
+L D + + T+L E +I ++ + A+ +H ++HRDIK +NVL+ +
Sbjct: 185 YLEGGNLTDVV---VKTELDEGQIAAVLQECLKALHFLHR--HSIVHRDIKSDNVLLGMN 239
Query: 201 DNFKLCDFGSTSMCFPIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIW 260
KL D G + P + +D V TP + SPE+++ + N K DIW
Sbjct: 240 GEVKLTDMGFCAQIQP--GSKRDTVV--------GTPYWMSPEILNKKQ---YNYKVDIW 286
Query: 261 ALGIFLYKLLFYTTPFELTGQFAILHSKYEIPQNG---------YSSKLINLIIIMLAEN 311
+LGI +++ P+ + L + Y I QNG SS+ N + L +
Sbjct: 287 SLGIMALEMIDGEPPYL---RETPLKAIYLIAQNGKPEIKQRDRLSSEFNNFLDKCLVVD 343
Query: 312 PSLRPNIYQVMHH 324
P R + +++ H
Sbjct: 344 PDQRADTTELLAH 356
>At4g24400 [T] KOG0583 Serine/threonine protein kinase
Length = 445
Score = 67.8 bits (164), Expect = 6e-11
Identities = 78/293 (26%), Positives = 133/293 (44%), Gaps = 44/293 (15%)
Query: 35 VVVGTHRCEILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDEN 94
VV + E+ + EG FA KVKF + T E + K++ I +KR +V
Sbjct: 2 VVRKVGKYELGRTIGEGTFA---KVKFAQNT-ETGESVAMKIVDRSTI--IKRKMV---- 51
Query: 95 GLNELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNK 154
++++ E+ MK +R P +V+ Y+ ASR +I +++E L D +
Sbjct: 52 --DQIKREISIMKLVR-HPCVVRLYEVLASRT-------KIYIILEYITGGELFDKIVRN 101
Query: 155 LATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMC 214
+L+E+E K + + + + H + HRD+K EN+L+D N K+ DFG +++
Sbjct: 102 --GRLSESEARKYFHQLIDGVDYCH--SKGVYHRDLKPENLLLDSQGNLKISDFGLSAL- 156
Query: 215 FPIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDL--YRCLPINEKSDIWALGIFLYKLLFY 272
Q + +L TP Y +PE++ Y +DIW+ G+ LY L+
Sbjct: 157 -----PEQGVTILKTTC---GTPNYVAPEVLSHKGYN----GAVADIWSCGVILYVLMAG 204
Query: 273 TTPFELTGQFAILHSKYEIPQNGYSSKLI----NLIIIMLAENPSLRPNIYQV 321
PF+ L+SK + + S +LI +L NP R I ++
Sbjct: 205 YLPFD-EMDLPTLYSKIDKAEFSCPSYFALGAKSLINRILDPNPETRITIAEI 256
>At3g19100 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 599
Score = 67.8 bits (164), Expect = 6e-11
Identities = 64/252 (25%), Positives = 115/252 (45%), Gaps = 36/252 (14%)
Query: 96 LNELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKL 155
+ ++R EV+ ++ L G N+VQ+YD+ + ++MELC LLD + +
Sbjct: 189 IEDVRREVKILRALSGHQNLVQFYDA-------FEDNANVYIVMELCGGGELLDRILAR- 240
Query: 156 ATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVL-VDKDDN--FKLCDFGSTS 212
K +E + ++ + N +A H ++HRD+K EN L K++N K+ DFG +
Sbjct: 241 GGKYSEDDAKAVLIQILNVVAFCHL--QGVVHRDLKPENFLYTSKEENSMLKVIDFGLSD 298
Query: 213 MCFPIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFY 272
P + + + + Y Y +PE+ L+R ++D+W++G+ Y LL
Sbjct: 299 FVRP----DERLNDIVGSAY------YVAPEV--LHR--SYTTEADVWSIGVIAYILLCG 344
Query: 273 TTPFELTGQFAILH-------SKYEIPQNGYSSKLINLIIIMLAENPSLRPNIYQVMHH- 324
+ PF + I S E P S + + + +L ++P R Q + H
Sbjct: 345 SRPFWARTESGIFRAVLKADPSFDEPPWPSLSFEAKDFVKRLLYKDPRKRMTASQALMHP 404
Query: 325 -VCSILKCDVPF 335
+ K D+PF
Sbjct: 405 WIAGYKKIDIPF 416
>YNL298w [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 842
Score = 67.4 bits (163), Expect = 8e-11
Identities = 70/308 (22%), Positives = 128/308 (40%), Gaps = 42/308 (13%)
Query: 43 EILEHLAEGGFANIYKVKFLELTNEMDA----GIDSKLLKAGDIACLKRVIVPDENGLNE 98
+++E +G ++Y + + E + D GD +K++++ +
Sbjct: 547 KVIEKAGQGASGSVYLAERTHIPTESNMIELINNDIDEPHVGDKVAIKQMVLSKQPRKEL 606
Query: 99 LRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLA-- 156
+ NE+ MK R NIV + ++ D + ++ME SL D + N
Sbjct: 607 IVNEILVMKDSRHK-NIVNFLEAYLRTDDD------LWVVMEFMEGGSLTDIIENSPTND 659
Query: 157 ---TKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSM 213
+ LTE +I I+ + + +H +IHRDIK +NVL+D K+ DFG
Sbjct: 660 NSHSPLTEPQIAYIVRETCQGLKFLH--DKHIIHRDIKSDNVLLDTRARVKITDFG---F 714
Query: 214 CFPIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYT 273
C + A + TP + +PE++ + +EK D+W+LGI ++L
Sbjct: 715 CARLTDKRSKRATMVG------TPYWMAPEVV---KQREYDEKIDVWSLGIMTIEMLEGE 765
Query: 274 TPFELTGQFAILHSKYEIPQNG---------YSSKLINLIIIMLAENPSLRPNIYQVMHH 324
P+ L + Y I NG S ++ + + L + R + +++HH
Sbjct: 766 PPYLNEDP---LKALYLIATNGTPKLKHPESLSLEIKRFLSVCLCVDVRYRASTEELLHH 822
Query: 325 VCSILKCD 332
+ CD
Sbjct: 823 GFFNMACD 830
>SPCC576.15c [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 592
Score = 67.4 bits (163), Expect = 8e-11
Identities = 80/325 (24%), Positives = 139/325 (42%), Gaps = 44/325 (13%)
Query: 10 PNSVAHTAATSAMIPNSHLLSPNTQVVVGTHRCEILEHLAEGGFANIYKVKFLELTNEMD 69
P++V H + + P+S +PN + V EIL EG ++ + LT +
Sbjct: 73 PSAVPHISTPN---PSSGASTPNIKRVSDFKFGEIL---GEGSYSTV-------LTATEN 119
Query: 70 AGIDSKLLKAGDIACLKRVIVPDENGLNELRNEVETMKQLRGSPNIVQYYDSNASRHPDG 129
+ +K D KR I+ ++ + E E + L P ++ + + H
Sbjct: 120 STKREYAIKVLD----KRHIIKEKKE-KYVNIEKEALCILSKHPGFIKLFYTFQDAH--- 171
Query: 130 SPGFEILLLMELCPKKSLLDYMNNKLATKLTEAEILKIMYDVSNAIAQMHYLP-TPLIHR 188
+ ++ L LLDY+N KL + Y + + + Y+ +IHR
Sbjct: 172 ----NLYFVLSLARNGELLDYIN-----KLGRFNEICAQYYAALIVDSIDYMHGRGVIHR 222
Query: 189 DIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTHQDIAVLTNNIYVHT-----TPQYRSPE 243
D+K EN+L+D + K+ DFGS + +H++ + H+ T +Y SPE
Sbjct: 223 DLKPENILLDDNMRTKITDFGSAKILNSSHGSHEEDTHHADKPQAHSRSFVGTARYVSPE 282
Query: 244 MIDLYRCLPINEKSDIWALGIFLYKLLFYTTPFELTGQF----AILHSKYEIPQNGYSSK 299
++ SDIWA G L+++L PF ++ +ILH YEIP + S
Sbjct: 283 VLS---DKIAGTASDIWAFGCILFQMLAGKPPFVAGNEYLTFQSILHLSYEIPPD-ISDV 338
Query: 300 LINLIIIMLAENPSLRPNIYQVMHH 324
+LI +L +P R + ++ H
Sbjct: 339 ASDLIKKLLVLDPKDRLTVDEIHQH 363
>Hs5453964 [T] KOG0583 Serine/threonine protein kinase
Length = 550
Score = 67.4 bits (163), Expect = 8e-11
Identities = 64/250 (25%), Positives = 115/250 (45%), Gaps = 35/250 (14%)
Query: 82 IACLKRVIVPDENGLNELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMEL 141
+ L R + + + ++R E++ +K R P+I++ Y ++ +I ++ME
Sbjct: 46 VKILNRQKIRSLDVVGKIRREIQNLKLFR-HPHIIKLYQVISTPS-------DIFMVMEY 97
Query: 142 CPKKSLLDYMNNKLATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDD 201
L DY+ +L E E ++ + + + H ++HRD+K ENVL+D
Sbjct: 98 VSGGELFDYICKN--GRLDEKESRRLFQQILSGVDYCHR--HMVVHRDLKPENVLLDAHM 153
Query: 202 NFKLCDFGSTSMCFPIVSTHQDIAVLTNNIYVHT---TPQYRSPEMIDLYRCLPINEKSD 258
N K+ DFG ++M +++ ++ T +P Y +PE+I L + D
Sbjct: 154 NAKIADFGLSNM-------------MSDGEFLRTSCGSPNYAAPEVIS--GRLYAGPEVD 198
Query: 259 IWALGIFLYKLLFYTTPFE----LTGQFAILHSKYEIPQNGYSSKLINLIIIMLAENPSL 314
IW+ G+ LY LL T PF+ T I + PQ + +I+L+ ML +P
Sbjct: 199 IWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQY-LNPSVISLLKHMLQVDPMK 257
Query: 315 RPNIYQVMHH 324
R +I + H
Sbjct: 258 RASIKDIREH 267
>Hs4503787 [T] KOG0197 Tyrosine kinases
Length = 505
Score = 67.4 bits (163), Expect = 8e-11
Identities = 64/256 (25%), Positives = 116/256 (45%), Gaps = 23/256 (8%)
Query: 87 RVIVPDENGLNELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKS 146
+ + P N+ E + MK LR P ++Q Y P I ++ EL S
Sbjct: 262 KTLKPGSMDPNDFLREAQIMKNLR-HPKLIQLYAVCTLEDP-------IYIITELMRHGS 313
Query: 147 LLDYMNNKLATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLC 206
L +Y+ N +K+ + + + V++ +A + IHRD+ NVLV + + +K+
Sbjct: 314 LQEYLQNDTGSKIHLTQQVDMAAQVASGMAYLE--SRNYIHRDLAARNVLVGEHNIYKVA 371
Query: 207 DFGSTSMCFPIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFL 266
DFG + F + ++DI + I + ++ +PE I R + KSD+W+ GI L
Sbjct: 372 DFG-LARVFKV--DNEDIYESRHEIKLPV--KWTAPEAI---RSNKFSIKSDVWSFGILL 423
Query: 267 YKLLFY-TTPFE-LTGQFAI--LHSKYEIPQ-NGYSSKLINLIIIMLAENPSLRPNIYQV 321
Y+++ Y P+ +TG I L Y +PQ + + N+++ P RP +
Sbjct: 424 YEIITYGKMPYSGMTGAQVIQMLAQNYRLPQPSNCPQQFYNIMLECWNAEPKERPTFETL 483
Query: 322 MHHVCSILKCDVPFTD 337
+ + D ++D
Sbjct: 484 RWKLEDYFETDSSYSD 499
>Hs22043888 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 765
Score = 67.4 bits (163), Expect = 8e-11
Identities = 70/240 (29%), Positives = 106/240 (44%), Gaps = 42/240 (17%)
Query: 99 LRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATK 158
+ NEV +++++ PNI+ + + E+ L+MEL L D + + +TK
Sbjct: 259 IENEVSILRRVK-HPNIIMLVEEMET-------ATELFLVMELVKGGDLFDAITS--STK 308
Query: 159 LTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLV----DKDDNFKLCDFGSTSMC 214
TE + ++Y+++NA+ +H L ++HRDIK EN+LV D + KL DFG +
Sbjct: 309 YTERDGSAMVYNLANALRYLHGLS--IVHRDIKPENLLVCEYPDGTKSLKLGDFGLAT-- 364
Query: 215 FPIVSTHQDIAVLTNNIY-VHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYT 273
V+ +Y V TP Y +PE+I K DIWA G+ Y LL
Sbjct: 365 -----------VVEGPLYTVCGTPTYVAPEIIAE---TGYGLKVDIWAAGVITYILLCGF 410
Query: 274 TPFELTGQF------AILHSKYEIPQ---NGYSSKLINLIIIMLAENPSLRPNIYQVMHH 324
PF IL K E P + + LI ML N R Q++ H
Sbjct: 411 PPFRSENNLQEDLFDQILAGKLEFPAPYWDNITDSAKELISQMLQVNVEARCTAGQILSH 470
>At5g12180 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 528
Score = 67.4 bits (163), Expect = 8e-11
Identities = 72/250 (28%), Positives = 116/250 (45%), Gaps = 38/250 (15%)
Query: 86 KRVIVPDENGLNELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKK 145
KR +V E+ + ++R EV+ M L G PNIV+ + +H + L+MELC
Sbjct: 106 KRKLVNKED-IEDVRREVQIMHHLTGQPNIVELKGAYEDKH-------SVHLVMELCAGG 157
Query: 146 SLLDYMNNK-LATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIEN-VLVDKDDN- 202
L D + K ++ A +L+ + + + M +IHRD+K EN +L++KD+N
Sbjct: 158 ELFDRIIAKGHYSERAAASLLRTIVQIVHTCHSM-----GVIHRDLKPENFLLLNKDENS 212
Query: 203 -FKLCDFGSTSMCFPIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWA 261
K DFG S+ + +DI + Y +PE++ ++DIW+
Sbjct: 213 PLKATDFG-LSVFYKPGEVFKDIV---------GSAYYIAPEVLK----RKYGPEADIWS 258
Query: 262 LGIFLYKLLFYTTPF---ELTGQF-AILHSKYEI---PQNGYSSKLINLIIIMLAENPSL 314
+G+ LY LL PF G F AIL + P S + +L+ ML +P
Sbjct: 259 IGVMLYILLCGVPPFWAESENGIFNAILRGHVDFSSDPWPSISPQAKDLVKKMLNSDPKQ 318
Query: 315 RPNIYQVMHH 324
R QV++H
Sbjct: 319 RLTAAQVLNH 328
>At1g48260 [T] KOG0583 Serine/threonine protein kinase
Length = 432
Score = 67.4 bits (163), Expect = 8e-11
Identities = 80/287 (27%), Positives = 131/287 (44%), Gaps = 55/287 (19%)
Query: 52 GFANIYKVKFL--ELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNELRNEVETMKQL 109
G N KVKF LT E A +K + +C+ R+ N +++ E+ T+K L
Sbjct: 18 GEGNSAKVKFAIDTLTGESFA------IKIIEKSCITRL-----NVSFQIKREIRTLKVL 66
Query: 110 RGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLTEAEILKIMY 169
+ PNIV+ ++ AS+ +I +++E L D + +K KL+E + K+
Sbjct: 67 K-HPNIVRLHEVLASKT-------KIYMVLECVTGGDLFDRIVSK--GKLSETQGRKMFQ 116
Query: 170 DVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTHQDIAVLTN 229
+ + ++ H + HRD+K+ENVL+D + K+ DFG +++ S H
Sbjct: 117 QLIDGVSYCHN--KGVFHRDLKLENVLLDAKGHIKITDFGLSAL-----SQH-----YRE 164
Query: 230 NIYVHTT---PQYRSPEMIDLYRCLPINE-----KSDIWALGIFLYKLLFYTTPFELTGQ 281
+ +HTT P Y +PE++ NE SDIW+ G+ LY +L PF+
Sbjct: 165 DGLLHTTCGSPNYVAPEVL-------ANEGYDGAASDIWSCGVILYVILTGCLPFDDANL 217
Query: 282 FAILHSKYE----IPQNGYSSKLINLIIIMLAENPSLRPNIYQVMHH 324
I ++ IP+ S +I ML NP R I + H
Sbjct: 218 AVICRKIFKGDPPIPR-WISLGAKTMIKRMLDPNPVTRVTIAGIKAH 263
>7296128 [T] KOG0583 Serine/threonine protein kinase
Length = 550
Score = 67.4 bits (163), Expect = 8e-11
Identities = 70/256 (27%), Positives = 110/256 (42%), Gaps = 33/256 (12%)
Query: 159 LTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIV 218
L E ++ + A+ MH L +HRDIK ENVL+ +D KL DFG ++
Sbjct: 140 LREIHAAPLLKQLLLAVKHMHSLG--YVHRDIKAENVLLLSEDRLKLADFGFSTQLINGT 197
Query: 219 STHQDIAVLTNNIYVHTTPQYRSPEMI--DLYRCLPINEKSDIWALGIFLYKLLFYTTPF 276
+Q + +P Y +PE+ D Y P+ D+WALGI LY ++ PF
Sbjct: 198 GANQKLDTFCG------SPPYAAPELFSDDHYIGAPV----DVWALGILLYFMVVGNMPF 247
Query: 277 ELTG----QFAILHSKYEIPQNGYSSKLINLIIIMLAENPSLRPNIYQVMHH---VCSIL 329
+ AIL Y +P S I LI +L P+ RP I +++ C L
Sbjct: 248 RAPTIPGLKAAILKGDYLLP-GQLSLPCIRLIQRILIHIPAQRPTIDDMLNSQFVTCPKL 306
Query: 330 KCDV------PFTDKYELGPYDFAKYSQYHLKLQQIQYQMFELYKNEKVTSGDVDKLNDL 383
D+ T + + S K ++ + E+ K + S + + +++
Sbjct: 307 SADLMQWEINQHTKPVKRSIFWVRSKSHRLRKSASLRDRYAEVVKKPAI-SMNTRQQDEM 365
Query: 384 FIQNFEIAPKQPIDKG 399
F+QNF QPI+ G
Sbjct: 366 FVQNF----LQPIEMG 377
>7291707 [T] KOG1152 Signal transduction serine/threonine kinase with
PAS/PAC sensor domain
Length = 1005
Score = 67.4 bits (163), Expect = 8e-11
Identities = 48/156 (30%), Positives = 84/156 (53%), Gaps = 17/156 (10%)
Query: 167 IMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTHQDIAV 226
I V++A+ +H ++HRDIK EN+++D++ KL DFGS +T +
Sbjct: 685 IFRQVADAVNYLH--EQKILHRDIKDENIIIDQNFTIKLIDFGS--------ATFMEEGK 734
Query: 227 LTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTPFELTGQFAILH 286
+ Y T +Y SPE++ R + + +IWALG+ LY L+F+ PF + L
Sbjct: 735 FFSTFY--GTTEYCSPEVLAGNRY--VGPELEIWALGVTLYVLMFFENPFIDVEE--TLK 788
Query: 287 SKYEIPQNGYSSKLINLIIIMLAENPSLRPNIYQVM 322
++ +IP+ S +L L+ ML ++P R ++Q++
Sbjct: 789 AEIQIPK-AVSEQLSRLLSSMLNKDPKYRCTMHQLI 823
>7290249 [R] KOG0586 Serine/threonine protein kinase
Length = 1398
Score = 67.4 bits (163), Expect = 8e-11
Identities = 68/259 (26%), Positives = 124/259 (47%), Gaps = 36/259 (13%)
Query: 92 DENGLNELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYM 151
D+ L ++ EVE MK+L+ P+I++ Y +++ I ++ E + + DY+
Sbjct: 178 DQTNLQKVYREVEIMKRLK-HPHIIKLYQVMETKNM-------IYIVSEYASQGEIFDYI 229
Query: 152 NNKLATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGST 211
+++E+ + + +A+ H ++HRD+K EN+L+D + N K+ DFG +
Sbjct: 230 AKY--GRMSESAARFKFWQIISAVEYCH--KKGIVHRDLKAENLLLDLNMNIKIADFGFS 285
Query: 212 SMCFP--IVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKL 269
+ P +++T +P Y +PE+ + + + DIW+LG+ LY L
Sbjct: 286 NHFKPGELLATWCG------------SPPYAAPEVFEGKQY--TGPEIDIWSLGVVLYVL 331
Query: 270 LFYTTPFE----LTGQFAILHSKYEIPQNGYSSKLINLIIIMLAENPSLRPNIYQVMHH- 324
+ PF+ + + +L ++ IP SS+ +LI ML P+ R I Q+ H
Sbjct: 332 VCGALPFDGSTLQSLRDRVLSGRFRIP-FFMSSECEHLIRRMLVLEPTRRYTIDQIKRHR 390
Query: 325 -VCSILKCDVPFTDKYELG 342
+C L V KY LG
Sbjct: 391 WMCPELLEHV-LIAKYNLG 408
>Hs4826878 [T] KOG0582 Ste20-like serine/threonine protein kinase
Length = 527
Score = 67.0 bits (162), Expect = 1e-10
Identities = 66/256 (25%), Positives = 116/256 (44%), Gaps = 45/256 (17%)
Query: 93 ENGLNELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMN 152
+ ++EL E++ M Q PNIV YY S + E+ L+M+L S+LD +
Sbjct: 54 QTSMDELLKEIQAMSQCH-HPNIVSYYTSFVVKD-------ELWLVMKLLSGGSVLDIIK 105
Query: 153 NKLATK------LTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLC 206
+ +A L E+ I I+ +V + +H IHRD+K N+L+ +D + ++
Sbjct: 106 HIVAKGEHKSGVLDESTIATILREVLEGLEYLH--KNGQIHRDVKAGNILLGEDGSVQIA 163
Query: 207 DFGSTSMCFPIVSTHQDIAVLTNNIYVHT---TPQYRSPEMIDLYRCLPINEKSDIWALG 263
DFG ++ ++T DI T N T TP + +PE+++ R + K+DIW+ G
Sbjct: 164 DFGVSA----FLATGGDI---TRNKVRKTFVGTPCWMAPEVMEQVR--GYDFKADIWSFG 214
Query: 264 IFLYKLLFYTTPFELTGQFAIL---------------HSKYEIPQNGYSSKLINLIIIML 308
I +L P+ +L K + + G S + +I + L
Sbjct: 215 ITAIELATGAAPYHKYPPMKVLMLTLQNDPPSLETGVQDKEMLKKYGKSFR--KMISLCL 272
Query: 309 AENPSLRPNIYQVMHH 324
++P RP +++ H
Sbjct: 273 QKDPEKRPTAAELLRH 288
>Hs20547878 [R] KOG0589 Serine/threonine protein kinase
Length = 758
Score = 67.0 bits (162), Expect = 1e-10
Identities = 55/197 (27%), Positives = 90/197 (44%), Gaps = 27/197 (13%)
Query: 135 ILLLMELCPKKSLLDYMNNKLATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIEN 194
+ ++ME C L+ +N + +E +IL +S + +H ++HRDIK +N
Sbjct: 52 LFIVMEYCDGGDLMKRINRQRGVLFSEDQILGWFVQISLGLKHIH--DRKILHRDIKAQN 109
Query: 195 VLVDKDDNF-KLCDFGSTSMCFPIVSTHQDIAVLTNNIYVHTT----PQYRSPEMIDLYR 249
+ + K+ KL DFG VL N++ + T P Y SPE+ +
Sbjct: 110 IFLSKNGMVAKLGDFGIAR-------------VLNNSMELARTCIGTPYYLSPEIC---Q 153
Query: 250 CLPINEKSDIWALGIFLYKLLFYTTPFELTG----QFAILHSKYEIPQNGYSSKLINLII 305
P N K+DIW+LG LY+L PFE I + + G+S +L +LI
Sbjct: 154 NKPYNNKTDIWSLGCVLYELCTLKHPFEGNNLQQLVLKICQAHFAPISPGFSRELHSLIS 213
Query: 306 IMLAENPSLRPNIYQVM 322
+ +P RP+I ++
Sbjct: 214 QLFQVSPRDRPSINSIL 230
>Hs19923407 [D] KOG0591 NIMA (never in mitosis)-related G2-specific
serine/threonine protein kinase
Length = 313
Score = 67.0 bits (162), Expect = 1e-10
Identities = 82/322 (25%), Positives = 130/322 (39%), Gaps = 54/322 (16%)
Query: 11 NSVAHTAATSAMIPNSHLLSPNTQVVVGTHRC-----EILEHLAEGGFANIYKVKFLELT 65
N++ HT + P PNT + RC +I + + G F+ +YK L
Sbjct: 15 NNLCHTLGP--VHPPDPQRHPNTL----SFRCSLADFQIEKKIGRGQFSEVYKATCL--- 65
Query: 66 NEMDAGIDSKLLKAGDIACLKRVIVPDENGLNELRNEVETMKQLRGSPNIVQYYDSNASR 125
+D K + + + + D + E+ +KQL PNI++Y DS
Sbjct: 66 ------LDRKTVALKKVQIFEMM---DAKARQDCVKEIGLLKQLN-HPNIIKYLDSFIED 115
Query: 126 HPDGSPGFEILLLMELCPKKSLLDYMN--NKLATKLTEAEILKIMYDVSNAIAQMHYLPT 183
+ E+ +++EL L + K + E + K + +A+ MH
Sbjct: 116 N-------ELNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEHMH--SR 166
Query: 184 PLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTHQDIAVLTNNIYVHTTPQYRSPE 243
++HRDIK NV + KL D G F +T V TP Y SPE
Sbjct: 167 RVMHRDIKPANVFITATGVVKLGDLG-LGRFFSSETTAAHSLV--------GTPYYMSPE 217
Query: 244 MIDLYRCLPINEKSDIWALGIFLYKLLFYTTPF--ELTGQFAILHSKYE-----IPQNGY 296
I N KSDIW+LG LY++ +PF + F++ + +P Y
Sbjct: 218 RIHENG---YNFKSDIWSLGCLLYEMAALQSPFYGDKMNLFSLCQKIEQCDYPPLPGEHY 274
Query: 297 SSKLINLIIIMLAENPSLRPNI 318
S KL L+ + + +P RP+I
Sbjct: 275 SEKLRELVSMCICPDPHQRPDI 296
>ECU02g0510 [D] KOG0596 Dual specificity; serine/threonine and tyrosine kinase
Length = 586
Score = 67.0 bits (162), Expect = 1e-10
Identities = 74/310 (23%), Positives = 130/310 (41%), Gaps = 52/310 (16%)
Query: 24 PNSHLLSPNTQVVVGTHRCEILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIA 83
P S + ++++ EIL+ + +GG + +YKV F ++
Sbjct: 271 PRSGAVRSRERIIIKGREIEILKQIGKGGSSKVYKVLF-----------------GSNVY 313
Query: 84 CLKRV-IVPDENGLNELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELC 142
LKRV ++ DE L+ NE+ + + +G+ IV+ D H G I
Sbjct: 314 ALKRVELIGDEKMLSSYINEINLLYKFKGTSEIVEIID-----HEVGEDYLHI------- 361
Query: 143 PKKSLLDYMNNKLATKLTEA----EILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVD 198
LL+Y L+ + + +K +++ I + ++ +IH D+K N L
Sbjct: 362 ----LLEYGETDLSKIIRKGGLSMNFIKDVWEQMLLIVKRVHIER-IIHCDLKPANFLFV 416
Query: 199 KDDNFKLCDFGSTSMCFPIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSD 258
K KL DFG + V + ++L+ T Y SPE + + + SD
Sbjct: 417 K-GRVKLIDFGISK-----VIRNDTTSILSEE--QCGTVNYMSPEAVTQNKS-KVARSSD 467
Query: 259 IWALGIFLYKLLFYTTPF-ELTGQFAILHSKYEIPQNGYSSKLINLIIIM---LAENPSL 314
IW+LG LY+++ P E + E + Y+SK +++M LA +P
Sbjct: 468 IWSLGCILYEMVHSNPPLHEYPNLIQKIQRLQEYSEFKYTSKNKAAVMVMKECLARDPKK 527
Query: 315 RPNIYQVMHH 324
RP I +++H
Sbjct: 528 RPTIDNLLNH 537
>At5g35580 [T] KOG1187 Serine/threonine protein kinase
Length = 457
Score = 67.0 bits (162), Expect = 1e-10
Identities = 75/271 (27%), Positives = 113/271 (41%), Gaps = 40/271 (14%)
Query: 7 ISRPNSVAHTAATSAMIPNSHL-LSPNTQVVVGTHRCEILEHLAEGGFANIYKVKFLELT 65
IS P+S + S + S L + ++ V T L EGGF ++K
Sbjct: 52 ISNPSSTTLSEDLSISLAGSDLHVFTQAELRVITQSFSSSNFLGEGGFGPVHK------- 104
Query: 66 NEMDAGIDSKL---LKAGDIACLKRVIVPDENGLNELRNEVETMKQLRGSPNIVQ---YY 119
ID KL LKA +A +K + + G E EV + +L+ PN+V+ Y
Sbjct: 105 ----GFIDDKLRPGLKAQPVA-VKLLDLDGLQGHREFMTEVMCLGKLK-HPNLVKLIGYC 158
Query: 120 DSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLTEAEILKIMYDVSNAIAQMH 179
A R LL+ E P+ SL + + + L L I Y+ + + +H
Sbjct: 159 CEEAHR----------LLVYEFMPRGSLESQLFRRCSLPLPWTTRLNIAYEAAKGLQFLH 208
Query: 180 YLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTHQDIAVLTNNIYVHTTPQY 239
P+I+RD K N+L+D D KL DFG TH V+ T Y
Sbjct: 209 EAEKPIIYRDFKASNILLDSDYTAKLSDFGLAKDGPQGDDTHVSTRVM-------GTQGY 261
Query: 240 RSPEMIDLYRCLPINEKSDIWALGIFLYKLL 270
+PE I + KSD+++ G+ L +LL
Sbjct: 262 AAPEYIMTGH---LTAKSDVYSFGVVLLELL 289
>At5g23580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 490
Score = 67.0 bits (162), Expect = 1e-10
Identities = 70/252 (27%), Positives = 109/252 (42%), Gaps = 42/252 (16%)
Query: 86 KRVIVPDENGLNELRNEVETMKQLRGSPNIVQY---YDSNASRHPDGSPGFEILLLMELC 142
KR ++ E+ + LR E++ M L PN+V+ Y+ + H L+MELC
Sbjct: 55 KRKLLCQEDYDDVLR-EIQIMHHLSEYPNVVRIESAYEDTKNVH----------LVMELC 103
Query: 143 PKKSLLDYMNNKLATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLV---DK 199
L D + + +E E K++ + + H L ++HRD+K EN L D+
Sbjct: 104 EGGELFDRIVKR--GHYSEREAAKLIKTIVGVVEACHSLG--VVHRDLKPENFLFSSSDE 159
Query: 200 DDNFKLCDFGSTSMCFPIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDI 259
D + K DFG + C P + + L + Y Y +PE++ + + D+
Sbjct: 160 DASLKSTDFGLSVFCTP----GEAFSELVGSAY------YVAPEVLHKH----YGPECDV 205
Query: 260 WALGIFLYKLLFYTTPFELTGQFA----ILHSKYEI---PQNGYSSKLINLIIIMLAENP 312
W+ G+ LY LL PF + IL K E P S +LI ML NP
Sbjct: 206 WSAGVILYILLCGFPPFWAESEIGIFRKILQGKLEFEINPWPSISESAKDLIKKMLESNP 265
Query: 313 SLRPNIYQVMHH 324
R +QV+ H
Sbjct: 266 KKRLTAHQVLCH 277
>At1g76040 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 534
Score = 67.0 bits (162), Expect = 1e-10
Identities = 68/242 (28%), Positives = 108/242 (44%), Gaps = 41/242 (16%)
Query: 96 LNELRNEVETMKQLRGSPNIVQY---YDSNASRHPDGSPGFEILLLMELCPKKSLLDYMN 152
+ ++R EV ++ L G PNIV++ Y+ + H L+MELC L D +
Sbjct: 127 IEDVRREVMILQHLTGQPNIVEFRGAYEDKDNLH----------LVMELCSGGELFDRII 176
Query: 153 NKLATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLV---DKDDNFKLCDFG 209
K +E E I + N + H++ ++HRD+K EN L+ ++D K DFG
Sbjct: 177 KK--GSYSEKEAANIFRQIVNVVHVCHFM--GVVHRDLKPENFLLVSNEEDSPIKATDFG 232
Query: 210 STSMCFPIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKL 269
S+ ++DI + Y +PE+ L+R ++ D+W+ G+ LY L
Sbjct: 233 -LSVFIEEGKVYRDIV---------GSAYYVAPEV--LHR--NYGKEIDVWSAGVMLYIL 278
Query: 270 LFYTTPF----ELTGQFAILHSKYEI---PQNGYSSKLINLIIIMLAENPSLRPNIYQVM 322
L PF E T AIL K ++ P S +LI ML +P R + +
Sbjct: 279 LSGVPPFWGETEKTIFEAILEGKLDLETSPWPTISESAKDLIRKMLIRDPKKRITAAEAL 338
Query: 323 HH 324
H
Sbjct: 339 EH 340
>7293666 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 576
Score = 67.0 bits (162), Expect = 1e-10
Identities = 69/284 (24%), Positives = 127/284 (44%), Gaps = 43/284 (15%)
Query: 45 LEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNELRNEVE 104
+ +GGFA Y++ +E + AG I K +I ++ E +
Sbjct: 28 MRFFGKGGFAKCYEIIDVETDDVF----------AGKIVSKKLMI---KHNQKEKTAQEI 74
Query: 105 TMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLTEAEI 164
T+ + PNIV++++ I +++ELC K+S+++ +K +TE E
Sbjct: 75 TIHRSLNHPNIVKFHNYFEDSQ-------NIYIVLELCKKRSMMEL--HKRRKSITEFEC 125
Query: 165 LKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTHQDI 224
+Y + + +H +IHRD+K+ N+ ++ + K+ DFG + + +
Sbjct: 126 RYYIYQIIQGVKYLH--DNRIIHRDLKLGNLFLNDLLHVKIGDFGLATRIEYEGERKKTL 183
Query: 225 AVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTPFE---LTGQ 281
TP Y +PE++ + + DIW++G +Y LL PFE L
Sbjct: 184 C---------GTPNYIAPEILTKKGH---SFEVDIWSIGCVMYTLLVGQPPFETKTLKDT 231
Query: 282 FA-ILHSKYEIPQNGYSSK-LINLIIIMLAENPSLRPNIYQVMH 323
++ I +Y +P Y K +++I ML NP RP I Q+++
Sbjct: 232 YSKIKKCEYRVP--SYLRKPAADMVIAMLQPNPESRPAIGQLLN 273
>SPBC4F6.06 [T] KOG0583 Serine/threonine protein kinase
Length = 891
Score = 66.6 bits (161), Expect = 1e-10
Identities = 51/202 (25%), Positives = 97/202 (47%), Gaps = 21/202 (10%)
Query: 137 LLMELCPKKSLLDYMNNKLATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVL 196
++ E +LDY+ + KL E + K + + +A++ +H ++HRD+KIEN+L
Sbjct: 218 MVFEFVDGGQMLDYIISH--GKLKEKQARKFVRQIGSALSYLHQ--NSVVHRDLKIENIL 273
Query: 197 VDKDDNFKLCDFGSTSMCFPIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEK 256
+ K + K+ DFG ++ + + ++Y + +PE+++ I +
Sbjct: 274 ISKTGDIKIIDFGLSN----LYRRQSRLRTFCGSLY------FAAPELLNAQPY--IGPE 321
Query: 257 SDIWALGIFLYKLLFYTTPFELTGQFAILHSKYEIPQNGYSSKLIN----LIIIMLAENP 312
D+W+ GI LY L+ PF+ + LH+K + Y S L + L+ ML +P
Sbjct: 322 VDVWSFGIVLYVLVCGKVPFD-DQNMSALHAKIKKGTVEYPSYLSSDCKGLLSRMLVTDP 380
Query: 313 SLRPNIYQVMHHVCSILKCDVP 334
R + +V++H I + P
Sbjct: 381 LKRATLEEVLNHPWMIRNYEGP 402
>SPBC4C3.11 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 420
Score = 66.6 bits (161), Expect = 1e-10
Identities = 55/225 (24%), Positives = 103/225 (45%), Gaps = 20/225 (8%)
Query: 73 DSKLLKAGDIACLKRVIVPDENGLNELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPG 132
D K K I L + + EN + + E ++M +L G P I + + +
Sbjct: 73 DKKSWKEYAIKVLDKKYIVKENKVKYVNIERDSMMRLNGFPGISRLFHTFQD-------D 125
Query: 133 FEILLLMELCPKKSLLDYMNNKLATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKI 192
++ ++EL P LL Y+ K L E + ++ ++I MH +IHRD+K
Sbjct: 126 LKLYYVLELAPNGELLQYI--KKYRFLDENCVRFYAAEILSSIEYMH--SCGIIHRDLKP 181
Query: 193 ENVLVDKDDNFKLCDFGSTSMCFPIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLP 252
EN+L D + + K+ DFG+ + P D ++ T +Y +PE++
Sbjct: 182 ENILFDGNMHVKITDFGTAKILPPKYVNSPDYTTFPSSFV--GTAEYVAPELLSRQ---V 236
Query: 253 INEKSDIWALGIFLYKLLFYTTPFELTGQ----FAILHSKYEIPQ 293
+++ SD+WA +Y+++ + PF + I+ +YE+P+
Sbjct: 237 VSKSSDLWAFACVVYQMIVGSPPFHGSNPNNIFKKIMSLEYELPK 281
>Hs16507245 [T] KOG0583 Serine/threonine protein kinase
Length = 358
Score = 66.6 bits (161), Expect = 1e-10
Identities = 56/196 (28%), Positives = 101/196 (50%), Gaps = 18/196 (9%)
Query: 135 ILLLMELCPKKSLLDYMNNKLATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIEN 194
I ++MEL + LL+++ K L E K+ +S+A+ H L ++HRD+K EN
Sbjct: 86 IYIIMELGVQGDLLEFI--KCQGALHEDVARKMFRQLSSAVKYCHDLD--IVHRDLKCEN 141
Query: 195 VLVDKDDNFKLCDFGSTSMCFPIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPIN 254
+L+DKD N KL DFG + C + ++ + + + Y +PE++ + +P
Sbjct: 142 LLLDKDFNIKLSDFGFSKRCL----RDSNGRIILSKTFCGSA-AYAAPEVL---QSIPYQ 193
Query: 255 EK-SDIWALGIFLYKLLFYTTPFELTGQFAILHSKYEIPQNGYSSKLI-----NLIIIML 308
K DIW+LG+ LY ++ + P++ + +L + E + SK + +LI ML
Sbjct: 194 PKVYDIWSLGVILYIMVCGSMPYDDSDIRKMLRIQKEHRVDFPRSKNLTCECKDLIYRML 253
Query: 309 AENPSLRPNIYQVMHH 324
+ S R +I +++ H
Sbjct: 254 QPDVSQRLHIDEILSH 269
>CE29453 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 740
Score = 66.6 bits (161), Expect = 1e-10
Identities = 75/323 (23%), Positives = 144/323 (44%), Gaps = 62/323 (19%)
Query: 99 LRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATK 158
L E E + ++R NI+Q+Y + G + ++ E K SL D+++++ +
Sbjct: 89 LEKEAEILSKIRHK-NIIQFYGICKAT------GNDFFIVTEYAEKGSLYDFIHSEESQS 141
Query: 159 LTEAE-------ILKIMYDVSNAIAQMHY-LPTPLIHRDIKIENVLVDKDDNFKLCDFGS 210
+ ++K +++ I +HY +IHRD+K +NV++DK+ K+CDFG+
Sbjct: 142 FASSSGGNSFDVVVKWASQIASGIQYLHYDAVDTIIHRDLKSKNVVLDKNLVCKICDFGT 201
Query: 211 TSMCFPIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLL 270
+ TH A T + SPEMI + + +D+W+ G+ L+++L
Sbjct: 202 SKDL-----THSCTAPSWGG-----TAAWMSPEMI--LQSEGLTTATDVWSYGVVLWEIL 249
Query: 271 FYTTPFELTGQFAILHSKYEIPQNGYSSKLINLIIIMLAENPSLRPNIYQVMHHVCSILK 330
P++ +F I I Q+G I LA PS + Q+M
Sbjct: 250 SKEVPYKDYSEFRIFTM---ITQSG----------ITLAIPPSCPAPLKQLM-------- 288
Query: 331 CDVPFTDKYELGPYDFAKYSQYHLKLQQIQYQMFELYKNEKVTSGDVDKLND-LFIQNFE 389
++ +++ P D A ++QIQ ++ L N+K D++K + L I+
Sbjct: 289 -----SNCWKMTPKDRA-------NMRQIQGELNRLAGNQKKMRKDLEKRREQLEIREKA 336
Query: 390 IAPKQPIDKGIGSVDQQEAPEDL 412
+ + +++ + + PED+
Sbjct: 337 LKQRMKVEQAVLD-SARHPPEDV 358
>CE20564 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 540
Score = 66.6 bits (161), Expect = 1e-10
Identities = 55/195 (28%), Positives = 93/195 (47%), Gaps = 25/195 (12%)
Query: 82 IACLKRVIVPDENGLNELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMEL 141
I +KR+ + + L NEV ++Q + PNIV+++ S+ E+ ++ME
Sbjct: 274 IVAVKRMNLRKQQRRELLFNEVSILRQYQ-HPNIVRFFSSHLVDD-------ELWVVMEF 325
Query: 142 CPKKSLLDYMNNKLATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDD 201
SL D + AT++TE +I I V A+ +H +IHRDIK +++L+ +D
Sbjct: 326 MEGGSLTDIVT---ATRMTEPQIATISRQVLGALDFLH--ARKVIHRDIKSDSILLKRDG 380
Query: 202 NFKLCDFGSTSMCFPIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWA 261
KL DFG V + + TP + + E+I P + ++DIW+
Sbjct: 381 TVKLTDFGFCGQLSEEVPRRRSLV---------GTPYWTAAEVIARE---PYDTRADIWS 428
Query: 262 LGIFLYKLLFYTTPF 276
GI L +++ PF
Sbjct: 429 FGIMLIEMVEGEPPF 443
>CE05425 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 542
Score = 66.6 bits (161), Expect = 1e-10
Identities = 55/195 (28%), Positives = 93/195 (47%), Gaps = 25/195 (12%)
Query: 82 IACLKRVIVPDENGLNELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMEL 141
I +KR+ + + L NEV ++Q + PNIV+++ S+ E+ ++ME
Sbjct: 276 IVAVKRMNLRKQQRRELLFNEVSILRQYQ-HPNIVRFFSSHLVDD-------ELWVVMEF 327
Query: 142 CPKKSLLDYMNNKLATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDD 201
SL D + AT++TE +I I V A+ +H +IHRDIK +++L+ +D
Sbjct: 328 MEGGSLTDIVT---ATRMTEPQIATISRQVLGALDFLH--ARKVIHRDIKSDSILLKRDG 382
Query: 202 NFKLCDFGSTSMCFPIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWA 261
KL DFG V + + TP + + E+I P + ++DIW+
Sbjct: 383 TVKLTDFGFCGQLSEEVPRRRSLV---------GTPYWTAAEVIARE---PYDTRADIWS 430
Query: 262 LGIFLYKLLFYTTPF 276
GI L +++ PF
Sbjct: 431 FGIMLIEMVEGEPPF 445
>At5g47850 [T] KOG1187 Serine/threonine protein kinase
Length = 751
Score = 66.6 bits (161), Expect = 1e-10
Identities = 67/274 (24%), Positives = 120/274 (43%), Gaps = 53/274 (19%)
Query: 34 QVVVGTHRCEILEHLAEGGFANIYK----------VKFLELTNEMDAGIDSKLLKAGDIA 83
++ + T + HL G F ++Y+ +K ELTN +G + +A +
Sbjct: 435 ELALATDGFSVRFHLGIGSFGSVYQGVLSDGRHVAIKRAELTNPTLSGTTMRHRRADKDS 494
Query: 84 CLKRVIVPDENGLNELRNEVETMKQL--RGSPNIVQYYDSNASRHPDGSPGFEILLLMEL 141
NE+E+M +L + ++ +Y+ R +L+ E
Sbjct: 495 AFV--------------NELESMSRLNHKNLVRLLGFYEDTEER----------ILVYEY 530
Query: 142 CPKKSLLDYMNNKLATKLTEAEILKIMYDVSNAIAQMH-YLPTPLIHRDIKIENVLVDKD 200
SL D+++N L+ L I D + I +H ++ P+IHRDIK N+L+D
Sbjct: 531 MKNGSLADHLHNPQFDPLSWQTRLMIALDAARGIQYLHEFIVPPVIHRDIKSSNILLDAT 590
Query: 201 DNFKLCDFGSTSMCFPIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIW 260
K+ DFG + M + D++ L +++ T Y PE Y+ + KSD++
Sbjct: 591 WTAKVSDFGLSQMG---PTEEDDVSHL--SLHAAGTLGYIDPE---YYKFQQLTTKSDVY 642
Query: 261 ALGIFLYKLLFYTTPFELTGQFAILHSKYEIPQN 294
+ G+ L +L L+G AI +++ E P+N
Sbjct: 643 SFGVVLLEL--------LSGHKAIHNNEDENPRN 668
>At3g17510 [T] KOG0583 Serine/threonine protein kinase
Length = 446
Score = 66.6 bits (161), Expect = 1e-10
Identities = 70/249 (28%), Positives = 118/249 (47%), Gaps = 40/249 (16%)
Query: 43 EILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNELRNE 102
E+ L EG F KVKF + D+ + + + + + D N +++ E
Sbjct: 21 ELGRTLGEGNFG---KVKFAK---------DTVSGHSFAVKIIDKSRIADLNFSLQIKRE 68
Query: 103 VETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLTEA 162
+ T+K L+ P+IV+ ++ AS+ +I ++MEL L D + + KLTE
Sbjct: 69 IRTLKMLK-HPHIVRLHEVLASKT-------KINMVMELVTGGELFDRIVSN--GKLTET 118
Query: 163 EILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTHQ 222
+ K+ + + I+ H + HRD+K+ENVL+D + K+ DFG ++ + +
Sbjct: 119 DGRKMFQQLIDGISYCH--SKGVFHRDLKLENVLLDAKGHIKITDFGLSA----LPQHFR 172
Query: 223 DIAVLTNNIYVHTT---PQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTPFELT 279
D +L HTT P Y +PE+ L SDIW+ G+ LY +L PF+
Sbjct: 173 DDGLL------HTTCGSPNYVAPEV--LANRGYDGAASDIWSCGVILYVILTGCLPFD-D 223
Query: 280 GQFAILHSK 288
A+L+ K
Sbjct: 224 RNLAVLYQK 232
>At3g01490 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 411
Score = 66.6 bits (161), Expect = 1e-10
Identities = 52/200 (26%), Positives = 95/200 (47%), Gaps = 21/200 (10%)
Query: 129 GSPGFEILLLMELCPKKSLLDYMNNKLATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHR 188
G P +++E CP +L ++ KL ++++ D++ ++ +H ++HR
Sbjct: 195 GMPSNVCCVVVEYCPGGALKSFLIKTRRRKLAFKVVIQLSLDLARGLSYLH--SQKIVHR 252
Query: 189 DIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLY 248
D+K EN+L+DK K+ DFG + S D+ T T Y +PE+++
Sbjct: 253 DVKTENMLLDKSRTLKIADFGVARL---EASNPNDMTGETG------TLGYMAPEVLN-- 301
Query: 249 RCLPINEKSDIWALGIFLYKLLFYTTPF------ELTGQFAILHSKYEIPQNGYSSKLIN 302
P N K D+++ GI L+++ P+ E+T + + EIP+ SS L N
Sbjct: 302 -GSPYNRKCDVYSFGICLWEIYCCDMPYPDLSFSEVTSAVVRQNLRPEIPRCCPSS-LAN 359
Query: 303 LIIIMLAENPSLRPNIYQVM 322
++ NP RP + +V+
Sbjct: 360 VMKRCWDANPEKRPEMEEVV 379
>At2g45590 [T] KOG1187 Serine/threonine protein kinase
Length = 683
Score = 66.6 bits (161), Expect = 1e-10
Identities = 49/165 (29%), Positives = 79/165 (47%), Gaps = 20/165 (12%)
Query: 47 HLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNELRNEVETM 106
HL GGF ++YK F +G DS +K D + G E NE+
Sbjct: 97 HLGHGGFGSVYKADF-------PSGGDSLAVKVMDTSA------GSLQGEREFHNELSLS 143
Query: 107 KQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLTE-AEIL 165
L GSP++V ++ R G +++L+ EL +SL D + ++ +L + +
Sbjct: 144 SHLIGSPHVVSLLGFSSDRR-----GRKLILVYELMANRSLQDALLDRKCVELMDWNKRF 198
Query: 166 KIMYDVSNAIAQMHYLPTPLI-HRDIKIENVLVDKDDNFKLCDFG 209
+I D++ I +H+ P+I H DIK N+L+D D K+ DFG
Sbjct: 199 EIATDIAKGIEFLHHCCDPIIIHGDIKPSNILLDSDFKAKIGDFG 243
>At2g28940 [T] KOG1187 Serine/threonine protein kinase
Length = 462
Score = 66.6 bits (161), Expect = 1e-10
Identities = 66/226 (29%), Positives = 105/226 (46%), Gaps = 26/226 (11%)
Query: 48 LAEGGFANIYKVKFLELTNEMDA-GIDSKLLKAGDIACLKRVIVPDENGLNELRNEVETM 106
+ EGGF +Y+ + + D+ G DSK+ A +K++ G E NEV +
Sbjct: 108 IGEGGFGCVYR----GVVDVSDSNGFDSKINVA-----VKQLNRQGLQGHKEWINEVNFL 158
Query: 107 KQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLAT-KLTEAEIL 165
+ PN+V+ A D G + LL+ EL KSL D++ ++ + L L
Sbjct: 159 GVVN-HPNLVKLVGYCAD---DDERGMQRLLVYELMCNKSLEDHLVGRVVSVSLPWMMRL 214
Query: 166 KIMYDVSNAIAQMHY-LPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTHQDI 224
KI D + +A +H + LI RD K N+L+D+ KL DFG P H
Sbjct: 215 KIAQDAAQGLAYLHEEMDFQLIFRDFKSSNILLDERFGAKLSDFGLARQGPPEGLGHVST 274
Query: 225 AVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLL 270
+V+ T Y +PE + + + KSD+W+ G+ LY+L+
Sbjct: 275 SVV-------GTVGYAAPEYVQTGK---LTAKSDVWSFGVVLYELI 310
>At2g23450 [T] KOG1187 Serine/threonine protein kinase
Length = 694
Score = 66.6 bits (161), Expect = 1e-10
Identities = 49/197 (24%), Positives = 98/197 (48%), Gaps = 24/197 (12%)
Query: 77 LKAGDIACLKRVIVPDENGLNELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEIL 136
L+ + +KR+ D L+++ NE++ + + PN+V+ + G P +
Sbjct: 353 LQNDEWVAIKRLRHRDSESLDQVMNEIKLLSSV-SHPNLVRLLGCCIEQ---GDP----V 404
Query: 137 LLMELCPKKSLLDYMNNKLATKLTEAEILKIMYDVSNAIAQMHY-LPTPLIHRDIKIENV 195
L+ E P +L +++ + L L + + AIA +H + P+ HRDIK N+
Sbjct: 405 LVYEYMPNGTLSEHLQRDRGSGLPWTLRLTVATQTAKAIAYLHSSMNPPIYHRDIKSTNI 464
Query: 196 LVDKDDNFKLCDFGSTSMCFPIVSTHQDIAVLTNNIYVHTTPQYRSPEMID--LYRCLPI 253
L+D D N K+ DFG + + +T + ++ T PQ +P +D ++C +
Sbjct: 465 LLDYDFNSKVADFGLSRL------------GMTESSHISTAPQ-GTPGYLDPQYHQCFHL 511
Query: 254 NEKSDIWALGIFLYKLL 270
++KSD+++ G+ L +++
Sbjct: 512 SDKSDVYSFGVVLAEII 528
>At1g50230 [R] KOG0597 Serine-threonine protein kinase FUSED
Length = 269
Score = 66.6 bits (161), Expect = 1e-10
Identities = 58/254 (22%), Positives = 109/254 (42%), Gaps = 48/254 (18%)
Query: 37 VGTHRCEILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPD--EN 94
+G ++E + EG F +YK + G +K ++ +
Sbjct: 1 MGVEDYHVIELVGEGSFGRVYK---------------GRRKYTGQTVAMKFIMKQGKTDK 45
Query: 95 GLNELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNK 154
++ LR E+E +++L+ NI++ DS + E ++ E + ++K
Sbjct: 46 DIHSLRQEIEILRKLKHE-NIIEMLDSFENAR-------EFCVVTEFAQGELFEILEDDK 97
Query: 155 LATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMC 214
L E ++ I + A+ +H +IHRD+K +N+L+ KLCDFG
Sbjct: 98 C---LPEEQVQAIAKQLVKALDYLH--SNRIIHRDMKPQNILIGAGSVVKLCDFGFAR-- 150
Query: 215 FPIVSTHQDIAVLTNNIYVHT---TPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLF 271
A+ TN + + + TP Y +PE++ + P + D+W+LG+ LY+L
Sbjct: 151 ----------AMSTNTVVLRSIKGTPLYMAPELV---KEQPYDRTVDLWSLGVILYELYV 197
Query: 272 YTTPFELTGQFAIL 285
PF +A++
Sbjct: 198 GQPPFYTNSVYALI 211
>At1g30270 [T] KOG0583 Serine/threonine protein kinase
Length = 480
Score = 66.6 bits (161), Expect = 1e-10
Identities = 77/294 (26%), Positives = 137/294 (46%), Gaps = 56/294 (19%)
Query: 43 EILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLN----- 97
E+ L EG FA KVKF ++ ++ GD +K ++ E L
Sbjct: 32 ELGRTLGEGTFA---KVKF------------ARNVENGDNVAIK--VIDKEKVLKNKMIA 74
Query: 98 ELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLAT 157
+++ E+ TMK ++ PN+++ ++ AS+ +I ++E L D +++
Sbjct: 75 QIKREISTMKLIK-HPNVIRMFEVMASKT-------KIYFVLEFVTGGELFDKISSN--G 124
Query: 158 KLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPI 217
+L E E K + NA+ H + HRD+K EN+L+D + K+ DFG +++
Sbjct: 125 RLKEDEARKYFQQLINAVDYCH--SRGVYHRDLKPENLLLDANGALKVSDFGLSAL---- 178
Query: 218 VSTHQDIAVLTNNIYVHT---TPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTT 274
Q+ +L HT TP Y +PE+I+ K+D+W+ G+ L+ L+
Sbjct: 179 --PQQEDGLL------HTTCGTPNYVAPEVINNKGY--DGAKADLWSCGVILFVLMAGYL 228
Query: 275 PFE---LTGQF-AILHSKYEIPQNGYSSKLINLIIIMLAENPSLRPNIYQVMHH 324
PFE LT + I +++ P +S+ LI +L NP+ R +V+ +
Sbjct: 229 PFEDSNLTSLYKKIFKAEFTCPP-WFSASAKKLIKRILDPNPATRITFAEVIEN 281
>At1g08650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 284
Score = 66.6 bits (161), Expect = 1e-10
Identities = 79/295 (26%), Positives = 126/295 (41%), Gaps = 45/295 (15%)
Query: 39 THRCEILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNE 98
T++ +I E + G F + +V + T + A K D A L D+
Sbjct: 12 TNKYQICEEIGRGRFGTVSRV-YAPATGDFFA------CKTIDKASLS-----DDLDRAC 59
Query: 99 LRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELC-PKKSLLDYMNNKLAT 157
L NE + M L PNIVQ +D + + + MEL P S+ D + + +
Sbjct: 60 LDNEPKLMALLSYHPNIVQIHDLIDTDST-------LSIFMELVHPSVSIYDRLVS--SG 110
Query: 158 KLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVD-KDDNFKLCDFGSTSMCFP 216
E + + A++ H ++HRDIK EN+LVD ++D K+CDFGS
Sbjct: 111 TFFEPQTASFAKQILQALSHCHRYG--VVHRDIKPENILVDLRNDTVKICDFGSGIWLGE 168
Query: 217 IVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTPF 276
+T + TP Y +PE++ Y EK D+W+ G+ LY +L T PF
Sbjct: 169 GETTEGVVG----------TPYYVAPEVLMGYS---YGEKVDLWSAGVVLYTMLAGTPPF 215
Query: 277 --ELTGQF--AILHSKYEIPQ---NGYSSKLINLIIIMLAENPSLRPNIYQVMHH 324
E + A+L P G SS + + ++ ++ S R + Q + H
Sbjct: 216 YGETAEEIFEAVLRGNLRFPTKIFRGVSSMAKDFLRKLICKDASRRFSAEQALRH 270
>CE06635 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 7160
Score = 66.2 bits (160), Expect = 2e-10
Identities = 69/291 (23%), Positives = 122/291 (41%), Gaps = 48/291 (16%)
Query: 43 EILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNELRNE 102
+I E L G F +++V N A K V+ P E+ +R E
Sbjct: 6264 DIHEELGTGAFGVVHRVTERATGNNFAA---------------KFVMTPHESDKETVRKE 6308
Query: 103 VETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLTEA 162
++TM LR P +V +D+ + E++++ E L + + ++ K++E
Sbjct: 6309 IQTMSVLR-HPTLVNLHDAFEDDN-------EMVMIYEFMSGGELFEKVADE-HNKMSED 6359
Query: 163 EILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVL--VDKDDNFKLCDFGSTSMCFPIVST 220
E ++ M V + MH +H D+K EN++ + + KL DFG T+ P
Sbjct: 6360 EAVEYMRQVCKGLCHMH--ENNYVHLDLKPENIMFTTKRSNELKLIDFGLTAHLDP---- 6413
Query: 221 HQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTPFELTG 280
Q + V T T ++ +PE+ + P+ +D+W++G+ Y LL +PF
Sbjct: 6414 KQSVKVTTG------TAEFAAPEVAE---GKPVGYYTDMWSVGVLSYILLSGLSPFGGEN 6464
Query: 281 QFAILHSKYEIPQN-------GYSSKLINLIIIMLAENPSLRPNIYQVMHH 324
L + N G S + I +L +P+ R I+Q + H
Sbjct: 6465 DDETLRNVKSCDWNMDDSAFSGISEDGKDFIRKLLLADPNTRMTIHQALEH 6515
>CE06634 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 6831
Score = 66.2 bits (160), Expect = 2e-10
Identities = 69/291 (23%), Positives = 122/291 (41%), Gaps = 48/291 (16%)
Query: 43 EILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNELRNE 102
+I E L G F +++V N A K V+ P E+ +R E
Sbjct: 5935 DIHEELGTGAFGVVHRVTERATGNNFAA---------------KFVMTPHESDKETVRKE 5979
Query: 103 VETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLTEA 162
++TM LR P +V +D+ + E++++ E L + + ++ K++E
Sbjct: 5980 IQTMSVLR-HPTLVNLHDAFEDDN-------EMVMIYEFMSGGELFEKVADE-HNKMSED 6030
Query: 163 EILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVL--VDKDDNFKLCDFGSTSMCFPIVST 220
E ++ M V + MH +H D+K EN++ + + KL DFG T+ P
Sbjct: 6031 EAVEYMRQVCKGLCHMH--ENNYVHLDLKPENIMFTTKRSNELKLIDFGLTAHLDP---- 6084
Query: 221 HQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTPFELTG 280
Q + V T T ++ +PE+ + P+ +D+W++G+ Y LL +PF
Sbjct: 6085 KQSVKVTTG------TAEFAAPEVAE---GKPVGYYTDMWSVGVLSYILLSGLSPFGGEN 6135
Query: 281 QFAILHSKYEIPQN-------GYSSKLINLIIIMLAENPSLRPNIYQVMHH 324
L + N G S + I +L +P+ R I+Q + H
Sbjct: 6136 DDETLRNVKSCDWNMDDSAFSGISEDGKDFIRKLLLADPNTRMTIHQALEH 6186
>At5g19360 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 523
Score = 66.2 bits (160), Expect = 2e-10
Identities = 71/250 (28%), Positives = 117/250 (46%), Gaps = 38/250 (15%)
Query: 86 KRVIVPDENGLNELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKK 145
KR +V E+ + ++R EV+ M L G PNIV+ + +H + L+MELC
Sbjct: 101 KRKLVNKED-IEDVRREVQIMHHLTGQPNIVELKGAYEDKH-------SVHLVMELCAGG 152
Query: 146 SLLDYMNNK-LATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIEN-VLVDKDDN- 202
L D + K ++ A +L+ + + + M +IHRD+K EN +L+ KD+N
Sbjct: 153 ELFDRIIAKGHYSERAAASLLRTIVQIIHTCHSM-----GVIHRDLKPENFLLLSKDENS 207
Query: 203 -FKLCDFGSTSMCFPIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWA 261
K DFG S+ + +DI + Y +PE++ ++DIW+
Sbjct: 208 PLKATDFG-LSVFYKPGEVFKDIV---------GSAYYIAPEVLR----RKYGPEADIWS 253
Query: 262 LGIFLYKLLFYTTPF---ELTGQF-AILHSKYEIPQNGY---SSKLINLIIIMLAENPSL 314
+G+ LY LL PF G F AIL + + + + S + +L+ ML +P
Sbjct: 254 IGVMLYILLCGVPPFWAESENGIFNAILSGQVDFSSDPWPVISPQAKDLVRKMLNSDPKQ 313
Query: 315 RPNIYQVMHH 324
R QV++H
Sbjct: 314 RLTAAQVLNH 323
>At4g38230 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 484
Score = 66.2 bits (160), Expect = 2e-10
Identities = 72/250 (28%), Positives = 114/250 (44%), Gaps = 38/250 (15%)
Query: 86 KRVIVPDENGLNELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKK 145
KR ++ E+ + ++R E++ M L G NIV A P + ++MELC
Sbjct: 57 KRKLISKED-VEDVRREIQIMHHLAGYKNIVTI--KGAYEDP-----LYVHIVMELCSGG 108
Query: 146 SLLDYMNNK-LATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIEN-VLVDKDDNF 203
L D + + ++ AE++KI+ V A + ++HRD+K EN +LV+KDD+F
Sbjct: 109 ELFDRIIQRGHYSERKAAELIKIIVGVVEACHSLG-----VMHRDLKPENFLLVNKDDDF 163
Query: 204 KL--CDFGSTSMCFPIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWA 261
L DFG S+ F +D+ +P Y +PE++ + ++D+W
Sbjct: 164 SLKAIDFG-LSVFFKPGQIFEDVV---------GSPYYVAPEVLLKH----YGPEADVWT 209
Query: 262 LGIFLYKLLFYTTPFELTGQFAIL------HSKYEI-PQNGYSSKLINLIIIMLAENPSL 314
G+ LY L+ PF Q I H ++ P S NLI ML PS
Sbjct: 210 AGVILYILVSGVPPFWAETQQGIFDAVLKGHIDFDSDPWPLISDSAKNLIRGMLCSRPSE 269
Query: 315 RPNIYQVMHH 324
R +QV+ H
Sbjct: 270 RLTAHQVLRH 279
>At3g24540 [T] KOG1187 Serine/threonine protein kinase
Length = 509
Score = 66.2 bits (160), Expect = 2e-10
Identities = 58/239 (24%), Positives = 102/239 (42%), Gaps = 40/239 (16%)
Query: 48 LAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNELRNEVETMK 107
L EGGF +YK +L G+ +K++ V G E + EV +
Sbjct: 185 LGEGGFGFVYK----------------GILNNGNEVAVKQLKVGSAQGEKEFQAEVNIIS 228
Query: 108 QL--RGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLTEAEIL 165
Q+ R ++V Y + A R LL+ E P +L +++ K + + L
Sbjct: 229 QIHHRNLVSLVGYCIAGAQR----------LLVYEFVPNNTLEFHLHGKGRPTMEWSLRL 278
Query: 166 KIMYDVSNAIAQMHYLPTP-LIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTHQDI 224
KI S ++ +H P +IHRDIK N+L+D K+ DFG + + T+ +
Sbjct: 279 KIAVSSSKGLSYLHENCNPKIIHRDIKAANILIDFKFEAKVADFGLAKIA---LDTNTHV 335
Query: 225 AVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTPFELTGQFA 283
+ + + P+Y + + EKSD+++ G+ L +L+ P + +A
Sbjct: 336 STRVMGTFGYLAPEYAASG--------KLTEKSDVYSFGVVLLELITGRRPVDANNVYA 386
>At2g02800 [T] KOG1187 Serine/threonine protein kinase
Length = 426
Score = 66.2 bits (160), Expect = 2e-10
Identities = 63/228 (27%), Positives = 97/228 (41%), Gaps = 34/228 (14%)
Query: 48 LAEGGFANIYKVKFLELTNEMDAGIDSKLLKA-----GDIACLKRVIVPDENGLNELRNE 102
L EGGF ++K ID L A G + +K++ G E E
Sbjct: 89 LGEGGFGYVFK-----------GWIDGTTLTASKPGSGIVVAVKKLKTEGYQGHKEWLTE 137
Query: 103 VETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLTEA 162
V + QL PN+V+ G LL+ E PK SL +++ + A LT A
Sbjct: 138 VNYLGQL-SHPNLVKLVGYCVE-------GENRLLVYEFMPKGSLENHLFRRGAQPLTWA 189
Query: 163 EILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTHQ 222
+K+ + + +H + +I+RD K N+L+D + N KL DFG TH
Sbjct: 190 IRMKVAIGAAKGLTFLHDAKSQVIYRDFKAANILLDAEFNSKLSDFGLAKAGPTGDKTHV 249
Query: 223 DIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLL 270
V+ T Y +PE + R + KSD+++ G+ L +LL
Sbjct: 250 STQVM-------GTHGYAAPEYVATGR---LTAKSDVYSFGVVLLELL 287
>Hs8393810_1 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 336
Score = 66.2 bits (160), Expect = 2e-10
Identities = 70/295 (23%), Positives = 130/295 (43%), Gaps = 45/295 (15%)
Query: 43 EILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNELRNE 102
EI E + +G + ++KV L N A + +++ P + E+ E
Sbjct: 22 EITETIGKGTYGKVFKV--LNKKNGQKAAV--------------KILDPIHDIDEEIEAE 65
Query: 103 VETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNN--KLATKLT 160
+K L PN+V++Y + D G ++ L++ELC S+ D + K +++
Sbjct: 66 YNILKALSDHPNVVRFYGIYFKK--DKVNGDKLWLVLELCSGGSVTDLVKGFLKRGERMS 123
Query: 161 EAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVST 220
E I I+++ + +H T IHRD+K N+L+ + KL DFG ++ + ST
Sbjct: 124 EPLIAYILHEALMGLQHLHNNKT--IHRDVKGNNILLTTEGGVKLVDFGVSAQ---LTST 178
Query: 221 HQDIAVLTNNIYVHTTPQYRSPEMIDLYRCL--PINEKSDIWALGIFLYKLLFYTTPFEL 278
N V TP + +PE+I + L + + D W+LGI +L P
Sbjct: 179 RH-----RRNTSV-GTPFWMAPEVIACEQQLDTTYDARCDTWSLGITAIELGDGDPPL-- 230
Query: 279 TGQFAILHSKYEIPQNG---------YSSKLINLIIIMLAENPSLRPNIYQVMHH 324
+ + ++IP+N +S++ + I L ++ RP + +++ H
Sbjct: 231 -ADLHPMRALFKIPRNPPPKLRQPELWSAEFNDFISKCLTKDYEKRPTVSELLQH 284
>Hs20544910_1 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 336
Score = 66.2 bits (160), Expect = 2e-10
Identities = 70/295 (23%), Positives = 130/295 (43%), Gaps = 45/295 (15%)
Query: 43 EILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNELRNE 102
EI E + +G + ++KV L N A + +++ P + E+ E
Sbjct: 22 EITETIGKGTYGKVFKV--LNKKNGQKAAV--------------KILDPIHDIDEEIEAE 65
Query: 103 VETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNN--KLATKLT 160
+K L PN+V++Y + D G ++ L++ELC S+ D + K +++
Sbjct: 66 YNILKALSDHPNVVRFYGIYFKK--DKVNGDKLWLVLELCSGGSVTDLVKGFLKRGERMS 123
Query: 161 EAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVST 220
E I I+++ + +H T IHRD+K N+L+ + KL DFG ++ + ST
Sbjct: 124 EPLIAYILHEALMGLQHLHNNKT--IHRDVKGNNILLTTEGGVKLVDFGVSAQ---LTST 178
Query: 221 HQDIAVLTNNIYVHTTPQYRSPEMIDLYRCL--PINEKSDIWALGIFLYKLLFYTTPFEL 278
N V TP + +PE+I + L + + D W+LGI +L P
Sbjct: 179 RH-----RRNTSV-GTPFWMAPEVIACEQQLDTTYDARCDTWSLGITAIELGDGDPPL-- 230
Query: 279 TGQFAILHSKYEIPQNG---------YSSKLINLIIIMLAENPSLRPNIYQVMHH 324
+ + ++IP+N +S++ + I L ++ RP + +++ H
Sbjct: 231 -ADLHPMRALFKIPRNPPPKLRQPELWSAEFNDFISKCLTKDYEKRPTVSELLQH 284
>YDR523c [T] KOG0201 Serine/threonine protein kinase
Length = 490
Score = 65.9 bits (159), Expect = 2e-10
Identities = 55/193 (28%), Positives = 94/193 (48%), Gaps = 23/193 (11%)
Query: 137 LLMELCPKKSLLDYMNNKLATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVL 196
++ME C S D + L E ++ I+++V+ + +H IHRDIK N+L
Sbjct: 91 IVMEYCGGGSCSDLLKRSYVNGLPEEKVSFIIHEVTLGLKYLH--EQRKIHRDIKAANIL 148
Query: 197 VDKDDNFKLCDFGSTSMCFPIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPI--- 253
++++ KL DFG VS H + L + +V TP + +PE++ C +
Sbjct: 149 LNEEGMVKLGDFG--------VSGHIR-STLKRDTFV-GTPYWMAPEVV----CCEVDGY 194
Query: 254 NEKSDIWALGIFLYKLLFYTTPFELTGQFAILHS--KYEIP--QNGYSSKLINLIIIMLA 309
NEK+DIW+LGI Y+LL P ++ + K + P Q +S + + L
Sbjct: 195 NEKADIWSLGITTYELLKGLPPLSKYDPMKVMTNLPKRKPPKLQGPFSDAAKDFVAGCLV 254
Query: 310 ENPSLRPNIYQVM 322
+ P+ RP+ Y ++
Sbjct: 255 KTPADRPSAYNLL 267
>HsM4759010 [T] KOG0576 Mitogen-activated protein kinase kinase kinase kinase
(MAP4K) germinal center kinase family
Length = 819
Score = 65.9 bits (159), Expect = 2e-10
Identities = 72/295 (24%), Positives = 129/295 (43%), Gaps = 50/295 (16%)
Query: 41 RCEILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNELR 100
R E+L+ + G + ++YK + +T+E+ A +K V + + ++ L+
Sbjct: 14 RFELLQRVGAGTYGDVYKARDT-VTSEL--------------AAVKIVKLDPGDDISSLQ 58
Query: 101 NEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLT 160
E+ +++ R PN+V Y S + + ME C SL + + AT
Sbjct: 59 QEITILRECR-HPNVVAYIGSYLRND-------RLWICMEFCGGGSLQEIYH---ATGPL 107
Query: 161 EAEILKIMYDVSNAIAQMHYLPTP-LIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVS 219
E +I Y + +H+L + IHRDIK N+L+ + KL DFG VS
Sbjct: 108 EER--QIAYVCRERLKGLHHLHSQGKIHRDIKGANLLLTLQGDVKLADFG--------VS 157
Query: 220 THQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKL------LFYT 273
+V ++ T P + +PE+ + R NE D+WALGI +L LF+
Sbjct: 158 GELTASVAKRRSFIGT-PYWMAPEVAAVERKGGYNELCDVWALGITAIELGELQPPLFHL 216
Query: 274 TPFELTGQFAILHSKYEIP----QNGYSSKLINLIIIMLAENPSLRPNIYQVMHH 324
P + + S ++ P + ++ + + + L +NP RP +++ H
Sbjct: 217 HP--MRALMLMSKSSFQPPKLRDKTRWTQNFHHFLKLALTKNPKKRPTAEKLLQH 269
>Hs8923922 [R] KOG0586 Serine/threonine protein kinase
Length = 795
Score = 65.9 bits (159), Expect = 2e-10
Identities = 63/233 (27%), Positives = 108/233 (46%), Gaps = 33/233 (14%)
Query: 96 LNELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYM--NN 153
L +L EV MK L PNIV+ ++ + + L+ME + DY+ +
Sbjct: 101 LQKLFREVRIMKILN-HPNIVKLFEVIETEKT-------LYLVMEYASGGEVFDYLVAHG 152
Query: 154 KLATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSM 213
++ K A+ +I+ +A+ H ++HRD+K EN+L+D D N K+ DFG ++
Sbjct: 153 RMKEKEARAKFRQIV----SAVQYCHQ--KYIVHRDLKAENLLLDGDMNIKIADFGFSN- 205
Query: 214 CFPIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYT 273
+ V +P Y +PE+ + + D+W+LG+ LY L+ +
Sbjct: 206 ---------EFTVGNKLDTFCGSPPYAAPELFQGKKY--DGPEVDVWSLGVILYTLVSGS 254
Query: 274 TPFELTG----QFAILHSKYEIPQNGYSSKLINLIIIMLAENPSLRPNIYQVM 322
PF+ + +L KY IP S+ NL+ +L NP R ++ Q+M
Sbjct: 255 LPFDGQNLKELRERVLRGKYRIPFY-MSTDCENLLKKLLVLNPIKRGSLEQIM 306
>Hs7661994 [T] KOG0579 Ste20-like serine/threonine protein kinase
Length = 1152
Score = 65.9 bits (159), Expect = 2e-10
Identities = 71/295 (24%), Positives = 123/295 (41%), Gaps = 53/295 (17%)
Query: 43 EILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNELRNE 102
EI+ L +G F +YK + E +A K + E L + E
Sbjct: 35 EIIGELGDGAFGKVYKAQNKE---------------TSVLAAAKVIDTKSEEELEDYMVE 79
Query: 103 VETMKQLRGSPNIVQ-----YYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLAT 157
++ + PNIV+ YY++N + +L+E C +D + +L
Sbjct: 80 IDILASC-DHPNIVKLLDAFYYENN------------LWILIEFC-AGGAVDAVMLELER 125
Query: 158 KLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPI 217
LTE++I + +A+ +H +IHRD+K N+L D + KL DFG
Sbjct: 126 PLTESQIQVVCKQTLDALNYLH--DNKIIHRDLKAGNILFTLDGDIKLADFG-------- 175
Query: 218 VSTHQDIAVLTNNIYVHTTPQYRSPE--MIDLYRCLPINEKSDIWALGIFLYKLLFYTTP 275
VS + + ++ TP + +PE M + + P + K+D+W+LGI L ++ P
Sbjct: 176 VSAKNTRTIQRRDSFI-GTPYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAEIEPP 234
Query: 276 FELTGQFAIL--HSKYEIP----QNGYSSKLINLIIIMLAENPSLRPNIYQVMHH 324
+L +K E P + +SS + + L +N R Q++ H
Sbjct: 235 HHELNPMRVLLKIAKSEPPTLAQPSRWSSNFKDFLKKCLEKNVDARWTTSQLLQH 289
>Hs4758700 [T] KOG0604 MAP kinase-activated protein kinase 2
Length = 382
Score = 65.9 bits (159), Expect = 2e-10
Identities = 71/239 (29%), Positives = 102/239 (41%), Gaps = 33/239 (13%)
Query: 100 RNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKL 159
R EV+ Q G P+IV D + H +L++ME L + +
Sbjct: 82 RQEVDHHWQASGGPHIVCILDVYENMHHGKRC---LLIIMECMEGGELFSRIQERGDQAF 138
Query: 160 TEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLV---DKDDNFKLCDFGSTSMCFP 216
TE E +IM D+ AI +H + HRD+K EN+L +KD KL DFG
Sbjct: 139 TEREAAEIMRDIGTAIQFLH--SHNIAHRDVKPENLLYTSKEKDAVLKLTDFGFAK---- 192
Query: 217 IVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTPF 276
T Q+ L Y TP Y +PE++ + ++ D+W+LG+ +Y LL PF
Sbjct: 193 --ETTQN--ALQTPCY---TPYYVAPEVLGPEK---YDKSCDMWSLGVIMYILLCGFPPF 242
Query: 277 -ELTGQFAILHSKYEIPQNGY----------SSKLINLIIIMLAENPSLRPNIYQVMHH 324
TGQ K I Y S LI ++L +P+ R I Q M+H
Sbjct: 243 YSNTGQAISPGMKRRIRLGQYGFPNPEWSEVSEDAKQLIRLLLKTDPTERLTITQFMNH 301
>Hs19923464 [T] KOG0577 Serine/threonine protein kinase
Length = 898
Score = 65.9 bits (159), Expect = 2e-10
Identities = 64/234 (27%), Positives = 98/234 (41%), Gaps = 34/234 (14%)
Query: 98 ELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELC--PKKSLLDYMNNKL 155
++ EV+ ++QL+ PN ++Y H L+ME C LL+ L
Sbjct: 68 DILKEVKFLRQLK-HPNTIEYKGCYLKEHT-------AWLVMEYCLGSASDLLEVHKKPL 119
Query: 156 ATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCF 215
E EI I + + +A +H LIHRDIK N+L+ + KL DFGS SM
Sbjct: 120 Q----EVEIAAITHGALHGLAYLH--SHALIHRDIKAGNILLTEPGQVKLADFGSASMAS 173
Query: 216 PIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTP 275
P N +V TP + +PE+I + K DIW+LGI +L P
Sbjct: 174 PA------------NSFV-GTPYWMAPEVILAMDEGQYDGKVDIWSLGITCIELAERKPP 220
Query: 276 -FELTGQFAILH----SKYEIPQNGYSSKLINLIIIMLAENPSLRPNIYQVMHH 324
F + A+ H + N ++ + L + P RP +++ H
Sbjct: 221 LFNMNAMSALYHIAQNDSPTLQSNEWTDSFRRFVDYCLQKIPQERPTSAELLRH 274
>CE03103 [KIT] KOG2345 Serine/threonine protein kinase/TGF-beta stimulated
factor
Length = 283
Score = 65.9 bits (159), Expect = 2e-10
Identities = 57/194 (29%), Positives = 91/194 (46%), Gaps = 12/194 (6%)
Query: 145 KSLLDYMNN-KLATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNF 203
++ L+Y+ K+ ++ E + LK + +AI Q+H H DIK N+L D
Sbjct: 66 QNFLEYIEELKIGGEVDELKHLKYFSGIVSAIEQLHGFE--FAHLDIKPANIL-KSGDTI 122
Query: 204 KLCDFGSTSMCFPIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALG 263
K+ DFGS + + T D + + YR+PE+ + + D+WALG
Sbjct: 123 KMIDFGSATKMPIEIKTSADHHRHKEDAEELCSMMYRAPELFNCEIGSTLTTAVDVWALG 182
Query: 264 IFLYKLLFYTTPF----ELTGQFAI-LHSKYEIPQN---GYSSKLINLIIIMLAENPSLR 315
+ LY+ L+ PF E G A+ S + I N S K INLI +L +P+ R
Sbjct: 183 VCLYEFLYLENPFNKIYEQGGSIALATQSPHMIKWNENRHISEKSINLIKSILIVDPNQR 242
Query: 316 PNIYQVMHHVCSIL 329
P I ++ V ++L
Sbjct: 243 PTIGELRAKVDNLL 256
>At5g04510 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 488
Score = 65.9 bits (159), Expect = 2e-10
Identities = 75/260 (28%), Positives = 118/260 (44%), Gaps = 38/260 (14%)
Query: 72 IDSKLLKAGDIACLK---RVIVPDENGLNELRNEVETMKQLRGSPNIVQYYDSNASRHPD 128
+ +K + G + LK + + EN ++ E + QL P I++ Y + D
Sbjct: 56 VRAKKKETGTVYALKIMDKKFITKENKTAYVKLERIVLDQLE-HPGIIKLYFT----FQD 110
Query: 129 GSPGFEILLLMELCPKKSLLDYMNNKLATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHR 188
S + + +E C L D + K +L+E E +V +A+ +H + LIHR
Sbjct: 111 TS---SLYMALESCEGGELFDQITRK--GRLSEDEARFYTAEVVDALEYIHSMG--LIHR 163
Query: 189 DIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTHQD--IAVLTNNIYVHT------TPQYR 240
DIK EN+L+ D + K+ DFGS V QD I VL N T Y
Sbjct: 164 DIKPENLLLTSDGHIKIADFGS-------VKPMQDSQITVLPNAASDDKACTFVGTAAYV 216
Query: 241 SPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTPFELTGQF----AILHSKYEIPQNGY 296
PE+++ P +D+WALG LY++L T+PF+ ++ I+ + P N +
Sbjct: 217 PPEVLN---SSPATFGNDLWALGCTLYQMLSGTSPFKDASEWLIFQRIIARDIKFP-NHF 272
Query: 297 SSKLINLIIIMLAENPSLRP 316
S +LI +L PS RP
Sbjct: 273 SEAARDLIDRLLDTEPSRRP 292
>At4g14480 [T] KOG0582 Ste20-like serine/threonine protein kinase
Length = 487
Score = 65.9 bits (159), Expect = 2e-10
Identities = 66/248 (26%), Positives = 110/248 (43%), Gaps = 34/248 (13%)
Query: 97 NELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLA 156
+ LR E +TM L PNI+ Y S + ++M SL +++
Sbjct: 57 DSLRRETKTMSLL-SHPNILNAYCSFTVDRC-------LWVVMPFMSCGSLHSIVSSSFP 108
Query: 157 TKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFG-STSMCF 215
+ L E I + + NAI+ +H +HRDIK N+LVD D + KL DFG S S+
Sbjct: 109 SGLPENCISVFLKETLNAISYLH--DQGHLHRDIKAGNILVDSDGSVKLADFGVSASIYE 166
Query: 216 PIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTP 275
P+ S+ + + TP + +PE++ + K+DIW+ GI +L P
Sbjct: 167 PVTSSSGTTSSSLRLTDIAGTPYWMAPEVVHSH--TGYGFKADIWSFGITALELAHGRPP 224
Query: 276 -----------FELTGQFAILHSKYEIPQNGYSSK--------LINLIIIMLAENPSLRP 316
++T +F S YEI +G S K ++ + L ++P+ RP
Sbjct: 225 LSHLPPLKSLLMKITKRFHF--SDYEINTSGSSKKGNKKFSKAFREMVGLCLEQDPTKRP 282
Query: 317 NIYQVMHH 324
+ +++ H
Sbjct: 283 SAEKLLKH 290
>At3g20860 [R] KOG0589 Serine/threonine protein kinase
Length = 427
Score = 65.9 bits (159), Expect = 2e-10
Identities = 57/228 (25%), Positives = 103/228 (45%), Gaps = 29/228 (12%)
Query: 102 EVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLTE 161
E+ + +L+ SP IV+Y DS + + ++ C + + +E
Sbjct: 62 EMSLISKLK-SPYIVEYKDSWVEKDC-------VCIVTSYCEGGDMTQMIKKSRGVFASE 113
Query: 162 AEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTH 221
++ + M + AI +H ++HRD+K N+ + K++ +L DFG +
Sbjct: 114 EKLCRWMVQLLLAIDYLHN--NRVLHRDLKCSNIFLTKENEVRLGDFGLAKLL-----GK 166
Query: 222 QDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTPFELTGQ 281
D+A + TP Y PE++ +P KSDIW+LG ++++ + F+
Sbjct: 167 DDLA-----SSMVGTPNYMCPELL---ADIPYGYKSDIWSLGCCMFEVAAHQPAFKAPDM 218
Query: 282 FAILH-----SKYEIPQNGYSSKLINLIIIMLAENPSLRPNIYQVMHH 324
A+++ S +P YSS L LI ML +NP RP +++ H
Sbjct: 219 AALINKINRSSLSPLPVM-YSSSLKRLIKSMLRKNPEHRPTAAELLRH 265
>At2g11520 [T] KOG1187 Serine/threonine protein kinase
Length = 310
Score = 65.9 bits (159), Expect = 2e-10
Identities = 66/250 (26%), Positives = 106/250 (42%), Gaps = 41/250 (16%)
Query: 33 TQVVVGTHRCEILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPD 92
+Q+ T + EGGF ++K +L G + +KR
Sbjct: 16 SQINTATGNFADSHQIGEGGFGVVFK----------------GVLDDGQVVAIKRAKKEH 59
Query: 93 -ENGLNELRNEVETMKQLRGSPNIVQ---YYDSNASRHPDGSPGFEILLLMELCPKKSLL 148
EN E ++EV+ + ++ G N+V+ Y D G E L++ E +L
Sbjct: 60 FENLRTEFKSEVDLLSKI-GHRNLVKLLGYVDK----------GDERLIITEYVRNGTLR 108
Query: 149 DYMNNKLATKLTEAEILKIMYDVSNAIAQMH-YLPTPLIHRDIKIENVLVDKDDNFKLCD 207
D+++ TKL + L+I+ DV + + +H Y +IHRDIK N+L+ K+ D
Sbjct: 109 DHLDGARGTKLNFNQRLEIVIDVCHGLTYLHSYAERQIIHRDIKSSNILLTDSMRAKVAD 168
Query: 208 FGSTSMCFPIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLY 267
FG + P S I V T Y PE + Y + KSD+++ GI L
Sbjct: 169 FG-FARGGPTDSNQTHILT-----QVKGTVGYLDPEYMKTYH---LTAKSDVYSFGILLV 219
Query: 268 KLLFYTTPFE 277
++L P E
Sbjct: 220 EILTGRRPVE 229
>Hs4759178 [D] KOG0580 Serine/threonine protein kinase
Length = 344
Score = 65.5 bits (158), Expect = 3e-10
Identities = 81/289 (28%), Positives = 119/289 (41%), Gaps = 49/289 (16%)
Query: 43 EILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVI---VPDENGLNEL 99
EI L +G F N+Y L E K+ I LK + + E ++L
Sbjct: 78 EIGRPLGKGKFGNVY------LAREK---------KSHFIVALKVLFKSQIEKEGVEHQL 122
Query: 100 RNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKL 159
R E+E L PNI++ Y+ R I L++E P+ L Y + +
Sbjct: 123 RREIEIQAHLH-HPNILRLYNYFYDRR-------RIYLILEYAPRGEL--YKELQKSCTF 172
Query: 160 TEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVS 219
E IM ++++A+ H +IHRDIK EN+L+ K+ DFG S
Sbjct: 173 DEQRTATIMEELADALMYCH--GKKVIHRDIKPENLLLGLKGELKIADFGW--------S 222
Query: 220 THQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTPFELT 279
H A + T Y PEMI+ NEK D+W +G+ Y+LL PFE
Sbjct: 223 VH---APSLRRKTMCGTLDYLPPEMIEGRMH---NEKVDLWCIGVLCYELLVGNPPFESA 276
Query: 280 GQ----FAILHSKYEIPQNGYSSKLINLIIIMLAENPSLRPNIYQVMHH 324
I+ + P + + +LI +L NPS R + QV H
Sbjct: 277 SHNETYRRIVKVDLKFPAS-VPTGAQDLISKLLRHNPSERLPLAQVSAH 324
>Hs4758016 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 607
Score = 65.5 bits (158), Expect = 3e-10
Identities = 68/281 (24%), Positives = 122/281 (43%), Gaps = 41/281 (14%)
Query: 48 LAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNELRNEVETMK 107
L +GGFA Y+ D++ A + + + V + ++ NE+E +
Sbjct: 29 LGKGGFARCYEAT------------DTETGSAYAVKVIPQSRVAKPHQREKILNEIELHR 76
Query: 108 QLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLTEAEILKI 167
L+ +IV++ S H + + I + +ELC +KSL K L E E+
Sbjct: 77 DLQHR-HIVRF-----SHHFEDADN--IYIFLELCSRKSLAHIW--KARHTLLEPEVRYY 126
Query: 168 MYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTHQDIAVL 227
+ + + + +H ++HRD+K+ N + ++ K+ DFG + P + I
Sbjct: 127 LRQILSGLKYLHQ--RGILHRDLKLGNFFITENMELKVGDFGLAARLEPPEQRKKTIC-- 182
Query: 228 TNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTPFELTG----QFA 283
TP Y +PE++ P ++D+W+LG +Y LL + PFE
Sbjct: 183 -------GTPNYVAPEVLLRQGHGP---EADVWSLGCVMYTLLCGSPPFETADLKETYRC 232
Query: 284 ILHSKYEIPQNGYSSKLINLIIIMLAENPSLRPNIYQVMHH 324
I Y +P + S L+ +L +P RP+I Q++ H
Sbjct: 233 IKQVHYTLPAS-LSLPARQLLAAILRASPRDRPSIDQILRH 272
>Hs4507273 [D] KOG0580 Serine/threonine protein kinase
Length = 275
Score = 65.5 bits (158), Expect = 3e-10
Identities = 68/238 (28%), Positives = 107/238 (44%), Gaps = 44/238 (18%)
Query: 43 EILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGL-NELRN 101
EI L +G F N+Y + E S + A + ++ ++ GL ++LR
Sbjct: 10 EIGRPLGKGKFGNVYLARLKE----------SHFIVALKVLFKSQI---EKEGLEHQLRR 56
Query: 102 EVETMKQLRGSPNIVQYYD--SNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKL 159
E+E L+ PNI++ Y+ +A R + L++E P+ L Y + + KL
Sbjct: 57 EIEIQAHLQ-HPNILRLYNYFHDARR---------VYLILEYAPRGEL--YKELQKSEKL 104
Query: 160 TEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVS 219
E I+ +V++A+ H +IHRDIK EN+L+ K+ DFG S
Sbjct: 105 DEQRTATIIEEVADALTYCH--DKKVIHRDIKPENLLLGFRGEVKIADFGW--------S 154
Query: 220 THQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTPFE 277
H L + T Y PEMI+ +EK D+W +G+ Y+LL PFE
Sbjct: 155 VHTP---LPERKTMCGTLDYLPPEMIE---GRTYDEKVDLWCIGVLCYELLVGYPPFE 206
>CE12472 [T] KOG0200 Fibroblast/platelet-derived growth factor receptor and
related receptor tyrosine kinases
Length = 495
Score = 65.5 bits (158), Expect = 3e-10
Identities = 53/194 (27%), Positives = 92/194 (47%), Gaps = 29/194 (14%)
Query: 149 DYMNNKLATKLTEAEILKIMYDVSNAIAQMHYLPT-PLIHRDIKIENVLVDKDDNFKLCD 207
DY+ + LT +++L ++N M YL + P++HRD+ + NVL+ K+ ++ D
Sbjct: 283 DYVIKESLDSLTTSDLLSFGLQIANG---MQYLASIPMVHRDLALRNVLLKKNKTIRIAD 339
Query: 208 FGSTSMCFPIVSTHQD----IAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALG 263
FG + TH++ I T + V ++ SPE D + EKSD+W+ G
Sbjct: 340 FG-------MARTHENKSYYIPQKTKDAPVPV--RWMSPEAFD---TMKFTEKSDVWSFG 387
Query: 264 IFLYKLL------FYTTPFELTGQFAILHSKYEIPQNGYSS-KLINLIIIMLAENPSLRP 316
I LY++ + P E ++ +HS PQ + +L +L+ + E P LRP
Sbjct: 388 ICLYEIFTLGQLPYPDVPSERIYEY--MHSGRRCPQPQHCHVELYDLMKLCWHEKPELRP 445
Query: 317 NIYQVMHHVCSILK 330
N + + +K
Sbjct: 446 NFSNCVEYFIGHMK 459
>At4g35780 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 553
Score = 65.5 bits (158), Expect = 3e-10
Identities = 57/241 (23%), Positives = 116/241 (47%), Gaps = 31/241 (12%)
Query: 96 LNELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKL 155
L E EV M+++R N+VQ+ + +R P+ + ++ E + S+ D+++
Sbjct: 314 LREFSQEVYIMRKVRHK-NVVQFIGA-CTRSPN------LCIVTEFMTRGSIYDFLHKHK 365
Query: 156 ATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCF 215
++ +LK+ DVS + +H +IHRD+K N+L+D+ + K+ DFG
Sbjct: 366 GVFKIQS-LLKVALDVSKGMNYLHQ--NNIIHRDLKTANLLMDEHEVVKVADFGVAR--- 419
Query: 216 PIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLL----- 270
V T + Y ++ +PE+I+ P + ++D+++ I L++LL
Sbjct: 420 --VQTESGVMTAETGTY-----RWMAPEVIE---HKPYDHRADVFSYAIVLWELLTGELP 469
Query: 271 -FYTTPFELTGQFAILHSKYEIPQNGYSSKLINLIIIMLAENPSLRPNIYQVMHHVCSIL 329
Y TP + + +IP+ + KL L+ ++P+LRPN +++ + ++
Sbjct: 470 YSYLTPLQAAVGVVQKGLRPKIPKETH-PKLTELLEKCWQQDPALRPNFAEIIEMLNQLI 528
Query: 330 K 330
+
Sbjct: 529 R 529
>At2g31010 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 375
Score = 65.5 bits (158), Expect = 3e-10
Identities = 59/217 (27%), Positives = 107/217 (49%), Gaps = 27/217 (12%)
Query: 96 LNELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKL 155
+ + NE+ + ++R PN+V + + ++ P S I MEL L+ K
Sbjct: 95 MEDFCNEISILSRVR-HPNVVLFLGA-CTKPPRLSM---ITEYMELGSLYYLIHMSGQK- 148
Query: 156 ATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCF 215
KL+ L+++ D+ + +H + ++HRD+K N LVDK K+CDFG +
Sbjct: 149 -KKLSWHRRLRMLRDICRGLMCIHRMK--IVHRDLKSANCLVDKHWTVKICDFGLSR--- 202
Query: 216 PIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTP 275
+ T +++ ++ TP++ +PE+I R P EK DI++LG+ +++L P
Sbjct: 203 --IMTDENMKDTSS----AGTPEWMAPELI---RNRPFTEKCDIFSLGVIMWELSTLRKP 253
Query: 276 FELTGQ----FAILH--SKYEIPQNGYSSKLINLIII 306
+E FA+ H S+ EIP S + L+++
Sbjct: 254 WEGVPPEKVVFAVAHEGSRLEIPDGPLSKLIAGLVLL 290
>At1g24030 [T] KOG1187 Serine/threonine protein kinase
Length = 303
Score = 65.5 bits (158), Expect = 3e-10
Identities = 72/280 (25%), Positives = 119/280 (41%), Gaps = 62/280 (22%)
Query: 48 LAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPD---ENGLNELRNEVE 104
L +GGF +Y+ LK G++ +K++ +P +G E R EV+
Sbjct: 14 LGKGGFGRVYQ----------------GTLKTGEVVAIKKMDLPTFKKADGEREFRVEVD 57
Query: 105 TMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLTEAEI 164
+ +L PN+V A DG F L+ E +L D++N K++ +
Sbjct: 58 ILSRL-DHPNLVSLIGYCA----DGKHRF---LVYEYMQNGNLQDHLNAKISWPIR---- 105
Query: 165 LKIMYDVSNAIAQMHYLPT---PLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTH 221
L+I + +A +H + P++HRD K NVL+D + N K+ DFG + T
Sbjct: 106 LRIALGAAKGLAYLHSSSSVGIPIVHRDFKSTNVLLDSNYNAKISDFGLAKLMPEGKDTC 165
Query: 222 QDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTPFELT-- 279
VL + + P+Y S + L +SDI+A G+ L +LL +LT
Sbjct: 166 VTARVL--GTFGYFDPEYTSTGKLTL--------QSDIYAFGVVLLELLTGRRAVDLTQG 215
Query: 280 --GQFAILHSK--------------YEIPQNGYSSKLINL 303
Q +L + E+P+N YS + I +
Sbjct: 216 PNEQNLVLQVRNILNDRKKLRKVIDVELPRNSYSMEAITM 255
>7298926 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 704
Score = 65.5 bits (158), Expect = 3e-10
Identities = 67/269 (24%), Positives = 114/269 (41%), Gaps = 42/269 (15%)
Query: 10 PNSVAHTAATSAMIPNSHLLSPNTQVVVG--THRCEILEHLAEGGFANIYKVKFLELTNE 67
PN+ A A M L T V VG + +E + +G +Y +E +
Sbjct: 396 PNTRAANAKKKKMSDEEILEKLRTIVSVGDPNRKYTKMEKIGQGASGTVYTA--IESSTG 453
Query: 68 MDAGIDSKLLKAGDIACLKRVIVPDENGLNELRNEVETMKQLRGSPNIVQYYDSNASRHP 127
M+ I K++ + + + NE+ M++ + PN+V Y DS
Sbjct: 454 MEVAI-------------KQMNLSQQPKKELIINEILVMRENK-HPNVVNYLDSYLVSE- 498
Query: 128 DGSPGFEILLLMELCPKKSLLDYMNNKLATKLTEAEILKIMYDVSNAIAQMHYLPTPLIH 187
E+ ++ME P SL D + T + E +I + +V A+ +H +IH
Sbjct: 499 ------ELWVVMEYLPGGSLTDVVTE---TCMDEGQIAAVCREVLQALEFLH--ANQVIH 547
Query: 188 RDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDL 247
RDIK +N+L+ D + KL DFG + P S + TP + +PE++
Sbjct: 548 RDIKSDNILLGLDGSVKLTDFGFCAQISPEQSKRTTMV---------GTPYWMAPEVVTR 598
Query: 248 YRCLPINEKSDIWALGIFLYKLLFYTTPF 276
+ P K D+W+LGI +++ P+
Sbjct: 599 KQYGP---KVDLWSLGIMAIEMVEGEPPY 624
>SPBC21.06c [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 1062
Score = 65.1 bits (157), Expect = 4e-10
Identities = 62/257 (24%), Positives = 120/257 (46%), Gaps = 38/257 (14%)
Query: 77 LKAGDIACLKRVIVPD--ENGLNELRNEVETMKQLRGSPNIVQY---YDSNASRHPDGSP 131
+K G+ +K+V + ++ L+ ++ E++ +K L PNIV+Y Y +N S
Sbjct: 29 IKNGETVAVKKVKLSKMLKSDLSVIKMEIDLLKNL-DHPNIVKYRGSYQTNDS------- 80
Query: 132 GFEILLLMELCPKKSLLDYMNNKLATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIK 191
+ +++E C SL N K+ E + + V + +H +IHRDIK
Sbjct: 81 ---LCIILEYCENGSLRSICKN--FGKIPENLVALYTFQVLQGLLYLHN--QGVIHRDIK 133
Query: 192 IENVLVDKDDNFKLCDFGSTSMCFPIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCL 251
N+L KD KL DFG + ++ +D +V+ +P + +PE+I+L +
Sbjct: 134 GANILTTKDGTIKLADFGVATK----INALEDHSVV-------GSPYWMAPEVIEL---V 179
Query: 252 PINEKSDIWALGIFLYKLLFYTTPF----ELTGQFAILHSKYEIPQNGYSSKLINLIIIM 307
SDIW++G + +LL P+ + F ++ ++ + SS + ++
Sbjct: 180 GATTASDIWSVGCTVIELLDGNPPYYDLDPTSALFRMVKDEHPPLPSNISSAAKSFLMQC 239
Query: 308 LAENPSLRPNIYQVMHH 324
++P+LR +++ H
Sbjct: 240 FQKDPNLRIKTRKLLKH 256
>SPBC17F3.02 [T] KOG0201 Serine/threonine protein kinase
Length = 652
Score = 65.1 bits (157), Expect = 4e-10
Identities = 62/233 (26%), Positives = 106/233 (44%), Gaps = 49/233 (21%)
Query: 92 DENGLNELRNEVETMKQLRGSP--NIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLD 149
DE+ +++++ EV + +L+ S NI++Y+ S G + ++M+ C S+
Sbjct: 46 DEDEVSDIQKEVAVLSELKQSDVENIIKYHGSYLV-------GTNLWIIMDYCHGGSVRT 98
Query: 150 YMNNKLATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFG 209
M A ++E I I+ + A+ +H+ +IHRDIK N+LV N KLCDFG
Sbjct: 99 LME---AGPISEPCISLILRETLQALKFIHH--AGIIHRDIKAANILVSMSGNVKLCDFG 153
Query: 210 STSMCFPIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYK- 268
V+ +I ++ TP + +PE+I + N +DIW+LGI Y+
Sbjct: 154 --------VAAELNINRRKRITFI-GTPYWMAPEVIRDGQ--EYNVMADIWSLGITAYEI 202
Query: 269 -----------------LLFYTTPFELTGQFAILHSKY------EIPQNGYSS 298
L+ +T P L G F+ L ++ ++PQ S
Sbjct: 203 ATGSPPHAKEDPFRAVYLIAHTAPPRLNGNFSALLKEFIASCLQDVPQRRLDS 255
>Hs7382496 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 545
Score = 65.1 bits (157), Expect = 4e-10
Identities = 71/281 (25%), Positives = 117/281 (41%), Gaps = 40/281 (14%)
Query: 10 PNSVAHTAATSAMIPNSHLLSPNTQVVVGTHRC---------EILEHLAEGGFANIYKVK 60
P + ATS + P + +P + T + EILE L K K
Sbjct: 210 PVTPTRDVATSPISPTENNTTPPDALTRNTEKQKKKPKMSDEEILEKLRSIVSVGDPKKK 269
Query: 61 FLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNELR-----NEVETMKQLRGSPNI 115
+ ++ G + A D+A + V + N + + NE+ M++ + +PNI
Sbjct: 270 YTRF-EKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMRENK-NPNI 327
Query: 116 VQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLTEAEILKIMYDVSNAI 175
V Y DS G E+ ++ME SL D + T + E +I + + A+
Sbjct: 328 VNYLDSYLV-------GDELWVVMEYLAGGSLTDVVTE---TCMDEGQIAAVCRECLQAL 377
Query: 176 AQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTHQDIAVLTNNIYVHT 235
+H +IHRDIK +N+L+ D + KL DFG + P S +
Sbjct: 378 EFLH--SNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMV---------G 426
Query: 236 TPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTPF 276
TP + +PE++ P K DIW+LGI +++ P+
Sbjct: 427 TPYWMAPEVVTRKAYGP---KVDIWSLGIMAIEMIEGEPPY 464
>Hs4505599 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 525
Score = 65.1 bits (157), Expect = 4e-10
Identities = 54/197 (27%), Positives = 91/197 (45%), Gaps = 24/197 (12%)
Query: 80 GDIACLKRVIVPDENGLNELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLM 139
G +K++ + + + NE+ MK+L+ +PNIV + DS G E+ ++M
Sbjct: 272 GQEVAIKQINLQKQPKKELIINEILVMKELK-NPNIVNFLDSYLV-------GDELFVVM 323
Query: 140 ELCPKKSLLDYMNNKLATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDK 199
E SL D + + EA+I + + A+ +H +IHRDIK +NVL+
Sbjct: 324 EYLAGGSLTDVVTETAC--MDEAQIAAVCRECLQALEFLH--ANQVIHRDIKSDNVLLGM 379
Query: 200 DDNFKLCDFGSTSMCFPIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDI 259
+ + KL DFG + P S + TP + +PE++ P K DI
Sbjct: 380 EGSVKLTDFGFCAQITPEQSKRSTMV---------GTPYWMAPEVVTRKAYGP---KVDI 427
Query: 260 WALGIFLYKLLFYTTPF 276
W+LGI +++ P+
Sbjct: 428 WSLGIMAIEMVEGEPPY 444
>Hs14771959 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 719
Score = 65.1 bits (157), Expect = 4e-10
Identities = 67/270 (24%), Positives = 115/270 (41%), Gaps = 35/270 (12%)
Query: 80 GDIACLKRVIVPDENGLNELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLM 139
G +K++ + + L NEV M+ N+V Y S G E+ ++M
Sbjct: 472 GKQVAVKKMDLRKQQRRELLFNEVVIMRDYHHD-NVVDMYSSYLV-------GDELWVVM 523
Query: 140 ELCPKKSLLDYMNNKLATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDK 199
E +L D + + T++ E +I + V A++ +H +IHRDIK +++L+
Sbjct: 524 EFLEGGALTDIVTH---TRMNEEQIATVCLSVLRALSYLHN--QGVIHRDIKSDSILLTS 578
Query: 200 DDNFKLCDFGSTSMCFPIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDI 259
D KL DFG + V + + TP + +PE+I LP + DI
Sbjct: 579 DGRIKLSDFGFCAQVSKEVPKRKSLV---------GTPYWMAPEVISR---LPYGTEVDI 626
Query: 260 WALGIFLYKLLFYTTP-FELTGQFAILHSKYEIPQ-----NGYSSKLINLIIIMLAENPS 313
W+LGI + +++ P F A+ + +P + SS L + +ML PS
Sbjct: 627 WSLGIMVIEMIDGEPPYFNEPPLQAMRRIRDSLPPRVKDLHKVSSVLRGFLDLMLVREPS 686
Query: 314 LRPNIYQVMHH----VCSILKCDVPFTDKY 339
R +++ H + C VP +Y
Sbjct: 687 QRATAQELLGHPFLKLAGPPSCIVPLMRQY 716
>CE26212 [T] KOG0582 Ste20-like serine/threonine protein kinase
Length = 545
Score = 65.1 bits (157), Expect = 4e-10
Identities = 59/254 (23%), Positives = 110/254 (43%), Gaps = 37/254 (14%)
Query: 93 ENGLNELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMN 152
+ ++EL +E++ M Q PN+V YY S ++ E+ ++M L S+LD +
Sbjct: 94 QTSVDELSHEIQAMSQCN-HPNVVSYYTSFIAQE-------ELWVVMRLLNCGSMLDILK 145
Query: 153 NKLAT---------KLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNF 203
K+ L E I ++ +V + H IHRDIK N+L+ D
Sbjct: 146 RKVKAIGKEQAQFGVLDEVSIATVLREVLKGLEYFHL--NGQIHRDIKAGNILLADDGTI 203
Query: 204 KLCDFGSTSMCFPIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALG 263
++ DFG + + S+ D++ TP + +PE+++ + + K+DIW+LG
Sbjct: 204 QIADFGVSGW---LASSGGDLSRQKVRHTFVGTPCWMAPEVME--QVQGYDFKADIWSLG 258
Query: 264 IFLYKLLFYTTPFELTGQFAIL-------------HSKYEIPQNGYSSKLINLIIIMLAE 310
I +L T P+ +L +++ + Y LI L +
Sbjct: 259 ILAIELATGTAPYHKYPPMKVLMLTLQNDPPTLETNAERKDQYKAYGKSFKTLIRDCLQK 318
Query: 311 NPSLRPNIYQVMHH 324
+P+ RP +++ +
Sbjct: 319 DPAKRPTASELLKY 332
>At5g03320 [T] KOG1187 Serine/threonine protein kinase
Length = 420
Score = 65.1 bits (157), Expect = 4e-10
Identities = 60/232 (25%), Positives = 98/232 (41%), Gaps = 38/232 (16%)
Query: 128 DGSPGFEILLLMELCPKKSLLDYMNNKLATKLTEAEILKIMYDVSNAIAQMHY-LPTPLI 186
D G + LL+ E P +S+ +++ + T LT L+I D + + +H + +I
Sbjct: 153 DDERGIQRLLVYEYMPNQSVEFHLSPRSPTVLTWDLRLRIAQDAARGLTYLHEEMDFQII 212
Query: 187 HRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTHQDIAVLTNNIYVHTTPQYRSPEMID 246
RD K N+L+D++ KL DFG + S+H V+ T Y +PE I
Sbjct: 213 FRDFKSSNILLDENWTAKLSDFGLARLGPSPGSSHVSTDVVG-------TMGYAAPEYIQ 265
Query: 247 LYRCLPINEKSDIWALGIFLYKLLFYTTPFEL-------------------TGQFAI--- 284
R + KSD+W G+F+Y+L+ P + T +F +
Sbjct: 266 TGR---LTSKSDVWGYGVFIYELITGRRPLDRNKPKGEQKLLEWVRPYLSDTRRFRLIVD 322
Query: 285 --LHSKYEIPQNGYSSKLINLIIIMLAENPSLRPNIYQVMHHVCSILKCDVP 334
L KY I KL + + L N RP + +V+ V I++ P
Sbjct: 323 PRLEGKYMIKS---VQKLAVVANLCLTRNAKARPKMSEVLEMVTKIVEASSP 371
>At5g01810 [T] KOG0583 Serine/threonine protein kinase
Length = 421
Score = 65.1 bits (157), Expect = 4e-10
Identities = 69/239 (28%), Positives = 110/239 (45%), Gaps = 40/239 (16%)
Query: 41 RCEILEHLAEGGFANIYKVKFLELTNEMDAGIDSK--LLKAGDIACLKRVIVPDENGLNE 98
R E+ + L +G FA +Y + L+ + + + K +LK G +KR
Sbjct: 11 RYEVGKFLGQGTFAKVYHARHLKTGDSVAIKVIDKERILKVGMTEQIKR----------- 59
Query: 99 LRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLAT- 157
E+ M+ LR PNIV+ ++ A++ +I +ME L NK++T
Sbjct: 60 ---EISAMRLLR-HPNIVELHEVMATKS-------KIYFVMEHVKGGELF----NKVSTG 104
Query: 158 KLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPI 217
KL E K + A+ H + HRD+K EN+L+D+ N K+ DFG +++
Sbjct: 105 KLREDVARKYFQQLVRAVDFCH--SRGVCHRDLKPENLLLDEHGNLKISDFGLSALS--- 159
Query: 218 VSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTPF 276
S QD + T TP Y +PE+I R K+D+W+ G+ L+ LL PF
Sbjct: 160 DSRRQDGLLHT----TCGTPAYVAPEVIS--RNGYDGFKADVWSCGVILFVLLAGYLPF 212
>At3g56760 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 577
Score = 65.1 bits (157), Expect = 4e-10
Identities = 52/202 (25%), Positives = 94/202 (45%), Gaps = 27/202 (13%)
Query: 96 LNELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKL 155
+ ++R EV+ ++ L G N+VQ+YD+ + ++MELC LLD + +
Sbjct: 169 IEDVRREVKILRALTGHKNLVQFYDAFEDDE-------NVYIVMELCQGGELLDKILQR- 220
Query: 156 ATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLV---DKDDNFKLCDFGSTS 212
K +E + K+M + + +A H ++HRD+K EN L D+ K DFG +
Sbjct: 221 GGKYSEVDAKKVMIQILSVVAYCHL--QGVVHRDLKPENFLFTTKDESSPLKAIDFGLSD 278
Query: 213 MCFPIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFY 272
P + + + + Y Y +PE+ L+R ++D+W++G+ Y LL
Sbjct: 279 YVRP----DERLNDIVGSAY------YVAPEV--LHR--TYGTEADMWSIGVIAYILLCG 324
Query: 273 TTPFELTGQFAILHSKYEIPQN 294
+ PF + I + + N
Sbjct: 325 SRPFWARSESGIFRAVLKAEPN 346
>At1g49730 [T] KOG1187 Serine/threonine protein kinase
Length = 658
Score = 65.1 bits (157), Expect = 4e-10
Identities = 74/311 (23%), Positives = 130/311 (41%), Gaps = 66/311 (21%)
Query: 48 LAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNELRNEVETMK 107
+ +GGF +YK +F + G IA +K++ E + E+ +
Sbjct: 328 IGQGGFGTVYKAEFND----------------GLIAAVKKMNKVSEQAEQDFCREIGLLA 371
Query: 108 QLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLTEAEILKI 167
+L N+V ++ E L+ + SL D+++ + +KI
Sbjct: 372 KLHHR-NLVALKGFCINKK-------ERFLVYDYMKNGSLKDHLHAIGKPPPSWGTRMKI 423
Query: 168 MYDVSNAIAQMH-YLPTPLIHRDIKIENVLVDKDDNFKLCDFG------STSMCFPIVST 220
DV+NA+ +H Y PL HRDIK N+L+D++ KL DFG S+CF V+T
Sbjct: 424 AIDVANALEYLHFYCDPPLCHRDIKSSNILLDENFVAKLSDFGLAHSSRDGSVCFEPVNT 483
Query: 221 HQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTP----- 275
+ TP Y PE + + EKSD+++ G+ L +L+
Sbjct: 484 D-----------IRGTPGYVDPEYVVTQE---LTEKSDVYSYGVVLLELITGRRAVDEGR 529
Query: 276 --FELTGQFAILHSKY--------EIPQNGYSSKLINLIIIML----AENPSLRPNIYQV 321
E++ +F + SK+ + N K ++ ++ ++ + RP+I QV
Sbjct: 530 NLVEMSQRFLLAKSKHLELVDPRIKDSINDAGGKQLDAVVTVVRLCTEKEGRSRPSIKQV 589
Query: 322 MHHVCSILKCD 332
+ +C CD
Sbjct: 590 LRLLCE--SCD 598
>Hs4758128_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 385
Score = 65.1 bits (157), Expect = 4e-10
Identities = 71/239 (29%), Positives = 110/239 (45%), Gaps = 40/239 (16%)
Query: 99 LRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATK 158
++NEV +++++ PNIV + + E+ L+MEL L D + + K
Sbjct: 89 IQNEVSILRRVK-HPNIVLLIE-------EMDVPTELYLVMELVKGGDLFDAITS--TNK 138
Query: 159 LTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLV----DKDDNFKLCDFGSTSMC 214
TE + ++Y++++AI +H L ++HRDIK EN+LV D + KL DFG
Sbjct: 139 YTERDASGMLYNLASAIKYLHSLN--IVHRDIKPENLLVYEHQDGSKSLKLGDFG----- 191
Query: 215 FPIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTT 274
++T D + T V TP Y +PE+I K DIWA G+ Y LL
Sbjct: 192 ---LATIVDGPLYT----VCGTPTYVAPEIIAE---TGYGLKVDIWAAGVITYILLCGFP 241
Query: 275 PFELTGQ------FAILHSKYEIPQ---NGYSSKLINLIIIMLAENPSLRPNIYQVMHH 324
PF +G IL + + P + S LI +ML + R + QV+ H
Sbjct: 242 PFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELITMMLLVDVDQRFSAVQVLEH 300
>SPCC1259.13 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 496
Score = 64.7 bits (156), Expect = 5e-10
Identities = 73/296 (24%), Positives = 124/296 (41%), Gaps = 57/296 (19%)
Query: 54 ANIYKVKFLE---LTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNELRNEVETMKQLR 110
A IY VKF+ T+ M+AG+ ++ + +E++ K
Sbjct: 32 AKIYAVKFVNKKHATSCMNAGVWAR----------------------RMASEIQLHKLCN 69
Query: 111 GSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLTEAEILKIMYD 170
G NI+ +Y N + +P +++E L D + + A+
Sbjct: 70 GHKNIIHFY--NTAENPQWR-----WVVLEFAQGGDLFDKIEPDVGIDEDVAQFY--FAQ 120
Query: 171 VSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTHQDIAVLTNN 230
+ I+ MH + HRD+K EN+L+D + N K+ DFG F + +++ + L N+
Sbjct: 121 LMEGISFMH--SKGVAHRDLKPENILLDYNGNLKISDFG-----FASLFSYKGKSRLLNS 173
Query: 231 IYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTPFE----LTGQFAILH 286
+P Y +PE+ Y K D+W+ GI L+ LL TP++ TG + +
Sbjct: 174 PV--GSPPYAAPEITQQYD----GSKVDVWSCGIILFALLLGNTPWDEAISNTGDYLLYK 227
Query: 287 SKYEIPQ----NGYSSKLINLIIIMLAENPSLRPNIYQVMHHVCSILKCDVPFTDK 338
+ E P N S ++I ML +P R ++ V+ H L PF K
Sbjct: 228 KQCERPSYHPWNLLSPGAYSIITGMLRSDPFKRYSVKHVVQH--PWLTSSTPFRTK 281
>Hs4506889 [T] KOG1006 Mitogen-activated protein kinase (MAPK) kinase MKK4
Length = 399
Score = 64.7 bits (156), Expect = 5e-10
Identities = 74/284 (26%), Positives = 118/284 (41%), Gaps = 40/284 (14%)
Query: 79 AGDIACLKRV-IVPDENGLNELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILL 137
+G I +KR+ DE +L +++ + + P IVQ+Y + R D +
Sbjct: 124 SGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYIVQFYGA-LFREGD------CWI 176
Query: 138 LMELCPKK--SLLDYMNNKLATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENV 195
MEL Y+ + L + E + KI A+ + +IHRDIK N+
Sbjct: 177 CMELMSTSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNHLKE-NLKIIHRDIKPSNI 235
Query: 196 LVDKDDNFKLCDFGSTSMCFPIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLP-IN 254
L+D+ N KLCDFG + ++ +D Y +PE ID +
Sbjct: 236 LLDRSGNIKLCDFGISGQLVDSIAKTRDAG----------CRPYMAPERIDPSASRQGYD 285
Query: 255 EKSDIWALGIFLYKLLFYTTPF-ELTGQFAILHS--KYEIPQ------NGYSSKLINLII 305
+SD+W+LGI LY+L P+ + F L K + PQ +S IN +
Sbjct: 286 VRSDVWSLGITLYELATGRFPYPKWNSVFDQLTQVVKGDPPQLSNSEEREFSPSFINFVN 345
Query: 306 IMLAENPSLRPNIYQVMHHVCSILKCDVPFTDKYELGPYDFAKY 349
+ L ++ S RP +++ H PF YE + A Y
Sbjct: 346 LCLTKDESKRPKYKELLKH---------PFILMYEERAVEVACY 380
>Hs21361133 [R] KOG0586 Serine/threonine protein kinase
Length = 752
Score = 64.7 bits (156), Expect = 5e-10
Identities = 80/339 (23%), Positives = 137/339 (39%), Gaps = 63/339 (18%)
Query: 9 RPNSVAHTAATSAMIPNSHLLSPNTQVVVGTHRCEILEHLAEGGFANIYKVKFLELTNEM 68
R + T+ + A NS + Q +G +R +L+ + +G FA + + + E+
Sbjct: 25 RQEVTSRTSRSGARCRNSIASCADEQPHIGNYR--LLKTIGKGNFAKVKLARHILTGREV 82
Query: 69 DAGIDSKLLKAGDIACLKRVIVPDENGLNELRNEVETMKQLRGSPNIVQYYDSNASRHPD 128
I K + L +L EV MK L PNIV+ ++ +
Sbjct: 83 AIKIIDKTQL-------------NPTSLQKLFREVRIMKILN-HPNIVKLFEVIETEKT- 127
Query: 129 GSPGFEILLLMELCPKKSLLDYMNNKLATKLTEA--------------------EILKIM 168
+ L+ME + DY+ K EA ++L +M
Sbjct: 128 ------LYLIMEYASGGEVFDYLVAHGKMKEKEARSKFRQGCQAGQTIKVQVSFDLLSLM 181
Query: 169 YD-VSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTHQDIAVL 227
+ + +A+ H ++HRD+K EN+L+D D N K+ DFG ++ + V
Sbjct: 182 FTFIVSAVQYCHQ--KRIVHRDLKAENLLLDADMNIKIADFGFSN----------EFTVG 229
Query: 228 TNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTPFELTG----QFA 283
+P Y +PE+ + + D+W+LG+ LY L+ + PF+ +
Sbjct: 230 GKLDTFCGSPPYAAPELFQGKKY--DGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRER 287
Query: 284 ILHSKYEIPQNGYSSKLINLIIIMLAENPSLRPNIYQVM 322
+L KY IP S+ NL+ L NP R + Q+M
Sbjct: 288 VLRGKYRIPFY-MSTDCENLLKRFLVLNPIKRGTLEQIM 325
>Hs13899225 [R] KOG0586 Serine/threonine protein kinase
Length = 688
Score = 64.7 bits (156), Expect = 5e-10
Identities = 74/305 (24%), Positives = 131/305 (42%), Gaps = 50/305 (16%)
Query: 25 NSHLLSPNTQVVVGTHRCEILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIAC 84
NS P Q VG +R +L + +G A + + + E+ I K
Sbjct: 44 NSIASCPEEQPHVGNYR--LLRTIGKGNSAKVKLARHILTGREVAIKIIDKTQL------ 95
Query: 85 LKRVIVPDENGLNELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPK 144
+ + L +L EV MK L PNIV+ ++ + + L+ME
Sbjct: 96 -------NPSSLQKLFREVRIMKGLN-HPNIVKLFEVIETEKT-------LYLVMEYASA 140
Query: 145 KSLLDYM--NNKLATKLTEAEILKIMYDVSNAIAQMHYLPTP-LIHRDIKIENVLVDKDD 201
+ DY+ + ++ K A+ +I ++ +HY ++HRD+K EN+L+D +
Sbjct: 141 GEVFDYLVSHGRMKEKEARAKFRQI-------VSAVHYCHQKNIVHRDLKAENLLLDAEA 193
Query: 202 NFKLCDFGSTSMCFPIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWA 261
N K+ DFG ++ F + S +P Y +PE+ + + DIW+
Sbjct: 194 NIKIADFGFSNE-FTLGSKLDTFC---------GSPPYAAPELFQGKKY--DGPEVDIWS 241
Query: 262 LGIFLYKLLFYTTPFELTG----QFAILHSKYEIPQNGYSSKLINLIIIMLAENPSLRPN 317
LG+ LY L+ + PF+ + +L KY +P S+ +++ L NP+ R
Sbjct: 242 LGVILYTLVSGSLPFDGHNLKELRERVLRGKYRVPFY-MSTDCESILRRFLVLNPAKRCT 300
Query: 318 IYQVM 322
+ Q+M
Sbjct: 301 LEQIM 305
>At3g10540 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 483
Score = 64.7 bits (156), Expect = 5e-10
Identities = 61/194 (31%), Positives = 93/194 (47%), Gaps = 27/194 (13%)
Query: 135 ILLLMELCPKKSLLDYMNNKLATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIEN 194
+ + +E C L D + K +L+E E +V +A+ +H + LIHRDIK EN
Sbjct: 115 LYMALESCEGGELFDQITRK--GRLSEDEARFYSAEVVDALEYIHNMG--LIHRDIKPEN 170
Query: 195 VLVDKDDNFKLCDFGSTSMCFPIVSTHQD--IAVLTNNIYVHT------TPQYRSPEMID 246
+L+ D + K+ DFGS V QD I VL N T Y PE+++
Sbjct: 171 LLLTLDGHIKIADFGS-------VKPMQDSQITVLPNAASDDKACTFVGTAAYVPPEVLN 223
Query: 247 LYRCLPINEKSDIWALGIFLYKLLFYTTPFELTGQF----AILHSKYEIPQNGYSSKLIN 302
P +D+WALG LY++L T+PF+ ++ I+ + P N +S +
Sbjct: 224 ---SSPATFGNDLWALGCTLYQMLSGTSPFKDASEWLIFQRIIARDIKFP-NHFSEAARD 279
Query: 303 LIIIMLAENPSLRP 316
LI +L +PS RP
Sbjct: 280 LIDRLLDTDPSRRP 293
>At3g09830 [T] KOG1187 Serine/threonine protein kinase
Length = 418
Score = 64.7 bits (156), Expect = 5e-10
Identities = 46/151 (30%), Positives = 72/151 (47%), Gaps = 11/151 (7%)
Query: 128 DGSPGFEILLLMELCPKKSLLDYMNNKLATKLTEAEILKIMYDVSNAIAQMHY-LPTPLI 186
D G + LL+ E P +S+ +++ + T LT L+I D + + +H + +I
Sbjct: 156 DDERGIQRLLVYEYMPNRSVEFHLSPRSLTVLTWDLRLRIAQDAARGLTYLHEEMEFQII 215
Query: 187 HRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTHQDIAVLTNNIYVHTTPQYRSPEMID 246
RD K N+L+D+D KL DFG + TH V+ T Y +PE I
Sbjct: 216 FRDFKSSNILLDEDWKAKLSDFGLARLGPSEGLTHVSTDVV-------GTMGYAAPEYIQ 268
Query: 247 LYRCLPINEKSDIWALGIFLYKLLFYTTPFE 277
R + KSD+W G+FLY+L+ P +
Sbjct: 269 TGR---LTSKSDVWGYGVFLYELITGRRPVD 296
>At2g17290 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 544
Score = 64.7 bits (156), Expect = 5e-10
Identities = 73/258 (28%), Positives = 117/258 (45%), Gaps = 41/258 (15%)
Query: 81 DIACL---KRVIVPDENGLNELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILL 137
D AC KR ++ E+ + ++R E++ M L G NIV A P + +
Sbjct: 110 DYACKSISKRKLISKED-VEDVRREIQIMHHLAGHKNIVTI--KGAYEDP-----LYVHI 161
Query: 138 LMELCPKKSLLDYMNNK-LATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIEN-V 195
+MELC L D + ++ ++ AE+ KI+ V A + ++HRD+K EN +
Sbjct: 162 VMELCAGGELFDRIIHRGHYSERKAAELTKIIVGVVEACHSLG-----VMHRDLKPENFL 216
Query: 196 LVDKDDNFKL--CDFGSTSMCFPIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPI 253
LV+KDD+F L DFG S+ F +D+ +P Y +PE++ +
Sbjct: 217 LVNKDDDFSLKAIDFG-LSVFFKPGQIFKDVV---------GSPYYVAPEVLLKH----Y 262
Query: 254 NEKSDIWALGIFLYKLLFYTTPFELTGQFAILHSKYE-------IPQNGYSSKLINLIII 306
++D+W G+ LY LL PF Q I + + P S +LI
Sbjct: 263 GPEADVWTAGVILYILLSGVPPFWAETQQGIFDAVLKGYIDFDTDPWPVISDSAKDLIRK 322
Query: 307 MLAENPSLRPNIYQVMHH 324
ML +PS R ++V+ H
Sbjct: 323 MLCSSPSERLTAHEVLRH 340
>At1g53570 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 608
Score = 64.7 bits (156), Expect = 5e-10
Identities = 74/286 (25%), Positives = 122/286 (41%), Gaps = 41/286 (14%)
Query: 52 GFANIYKVKFLE--LTNEMDAGIDSKLLKAGDIACLKRV-IVPDENG----LNELRNEVE 104
GF+ K KFL ++ G +S+ G + +K V ++ D+ L +L E+
Sbjct: 210 GFSTWKKGKFLGSGTFGQVYLGFNSE---KGKMCAIKEVKVISDDQTSKECLKQLNQEIN 266
Query: 105 TMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLTEAEI 164
+ QL PNIVQYY S S + + +E S+ + + TE I
Sbjct: 267 LLNQLC-HPNIVQYYGSELSEET-------LSVYLEYVSGGSIHKLLKDY--GSFTEPVI 316
Query: 165 LKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTHQDI 224
+ +A +H T +HRDIK N+LVD + KL DFG + +
Sbjct: 317 QNYTRQILAGLAYLHGRNT--VHRDIKGANILVDPNGEIKLADFGMA----------KHV 364
Query: 225 AVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTPFE----LTG 280
+ + +P + +PE++ DIW+LG + ++ P+ +
Sbjct: 365 TAFSTMLSFKGSPYWMAPEVVMSQN--GYTHAVDIWSLGCTILEMATSKPPWSQFEGVAA 422
Query: 281 QFAILHSK--YEIPQNGYSSKLINLIIIMLAENPSLRPNIYQVMHH 324
F I +SK EIP + S+ N I + L NP++RP Q++ H
Sbjct: 423 IFKIGNSKDTPEIPDH-LSNDAKNFIRLCLQRNPTVRPTASQLLEH 467
>At1g29230 [T] KOG0583 Serine/threonine protein kinase
Length = 520
Score = 64.7 bits (156), Expect = 5e-10
Identities = 72/302 (23%), Positives = 136/302 (44%), Gaps = 51/302 (16%)
Query: 30 SPNTQVVVGTHRCEILEHLAEGGFANIYKVKFLELTNEMDAGI--DSKLLKAGDIACLKR 87
SP +++G + E+ + L G FA +Y + ++ +++ + K++K+G +A +KR
Sbjct: 64 SPRNNILMGKY--ELGKLLGHGTFAKVYLAQNIKSGDKVAIKVIDKEKIMKSGLVAHIKR 121
Query: 88 VIVPDENGLNELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSL 147
E+ ++++R P IV ++ A++ +I +ME L
Sbjct: 122 --------------EISILRRVR-HPYIVHLFEVMATKS-------KIYFVMEYVGGGEL 159
Query: 148 LDYMNNKLATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCD 207
N +L E + + ++++ H + HRD+K EN+L+D N K+ D
Sbjct: 160 F---NTVAKGRLPEETARRYFQQLISSVSFCH--GRGVYHRDLKPENLLLDNKGNLKVSD 214
Query: 208 FGSTSMCFPIVSTHQDIAVLTNNIYVHT---TPQYRSPEMIDLYRCLPINEKSDIWALGI 264
FG +++ L + HT TP Y +PE+ L R K+D+W+ G+
Sbjct: 215 FGLSAVA----------EQLRQDGLCHTFCGTPAYIAPEV--LTRKGYDAAKADVWSCGV 262
Query: 265 FLYKLLFYTTPFE----LTGQFAILHSKYEIPQNGYSSKLINLIIIMLAENPSLRPNIYQ 320
L+ L+ PF + I ++ P+ +SS L+ L+ +L NP R I +
Sbjct: 263 ILFVLMAGHIPFYDKNIMVMYKKIYKGEFRCPR-WFSSDLVRLLTRLLDTNPDTRITIPE 321
Query: 321 VM 322
+M
Sbjct: 322 IM 323
>7303019 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 913
Score = 64.7 bits (156), Expect = 5e-10
Identities = 65/238 (27%), Positives = 106/238 (44%), Gaps = 40/238 (16%)
Query: 41 RCEILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNELR 100
R EI+E L +G F +YKV+ + G +LL A I C+K ++
Sbjct: 277 RFEIIEELGKGRFGIVYKVQ--------ERGQPEQLLAAKVIKCIK------SQDRQKVL 322
Query: 101 NEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLT 160
E+ M+ L+ P ++Q S S EI+++ME L + + T LT
Sbjct: 323 EEISIMRALQ-HPKLLQLAASFESPR-------EIVMVMEYITGGELFERVVADDFT-LT 373
Query: 161 EAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDK--DDNFKLCDFGSTSMCFPIV 218
E + + + V + +A MH ++H D+K EN++ K+ DFG +
Sbjct: 374 EMDCILFLRQVCDGVAYMH--GQSVVHLDLKPENIMCHTRTSHQIKIIDFGLAQR----L 427
Query: 219 STHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTPF 276
T + VL TP++ PE+I PI +SD+W++G+ Y LL +PF
Sbjct: 428 DTKAPVRVLFG------TPEFIPPEIISYE---PIGFQSDMWSVGVICYVLLSGLSPF 476
>Hs5453966 [T] KOG0583 Serine/threonine protein kinase
Length = 552
Score = 64.3 bits (155), Expect = 7e-10
Identities = 62/250 (24%), Positives = 113/250 (44%), Gaps = 35/250 (14%)
Query: 82 IACLKRVIVPDENGLNELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMEL 141
+ L R + + + +++ E++ +K R P+I++ Y S + ++ME
Sbjct: 44 VKILNRQKIRSLDVVGKIKREIQNLKLFR-HPHIIKLYQVI-------STPTDFFMVMEY 95
Query: 142 CPKKSLLDYMNNKLATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDD 201
L DY+ ++ E E ++ + +A+ H ++HRD+K ENVL+D
Sbjct: 96 VSGGELFDYICKH--GRVEEMEARRLFQQILSAVDYCHR--HMVVHRDLKPENVLLDAHM 151
Query: 202 NFKLCDFGSTSMCFPIVSTHQDIAVLTNNIYVHT---TPQYRSPEMIDLYRCLPINEKSD 258
N K+ DFG ++M +++ ++ T +P Y +PE+I L + D
Sbjct: 152 NAKIADFGLSNM-------------MSDGEFLRTSCGSPNYTAPEVIS--GRLYAGPEVD 196
Query: 259 IWALGIFLYKLLFYTTPFE----LTGQFAILHSKYEIPQNGYSSKLINLIIIMLAENPSL 314
IW+ G+ LY LL T PF+ T I + IP+ + + L++ ML +P
Sbjct: 197 IWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEY-LNRSVATLLMHMLQVDPLK 255
Query: 315 RPNIYQVMHH 324
R I + H
Sbjct: 256 RATIKDIREH 265
>Hs4557511 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 454
Score = 64.3 bits (155), Expect = 7e-10
Identities = 74/294 (25%), Positives = 135/294 (45%), Gaps = 47/294 (15%)
Query: 43 EILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNELRNE 102
E+ E L G FA + K + E A K +K ++ +R + +E + E
Sbjct: 14 EMGEELGSGQFAIVRKCRQKGTGKEYAA----KFIKKRRLSSSRRGVSREE-----IERE 64
Query: 103 VETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLATKLTEA 162
V ++++R PNI+ +D ++ +++L++EL L D++ K LTE
Sbjct: 65 VNILREIR-HPNIITLHDIFENKT-------DVVLILELVSGGELFDFLAEK--ESLTED 114
Query: 163 EILKIMYDVSNAIAQMHYLPTPLI-HRDIKIENV-LVDKD---DNFKLCDFGSTSMCFPI 217
E + + + + + HYL + I H D+K EN+ L+DK+ KL DFG
Sbjct: 115 EATQFLKQILDGV---HYLHSKRIAHFDLKPENIMLLDKNVPNPRIKLIDFG-------- 163
Query: 218 VSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTPF- 276
++ + NI+ TP++ +PE+++ P+ ++D+W++G+ Y LL +PF
Sbjct: 164 IAHKIEAGNEFKNIF--GTPEFVAPEIVNYE---PLGLEADMWSIGVITYILLSGASPFL 218
Query: 277 ------ELTGQFAILHSKYEIPQNGYSSKLINLIIIMLAENPSLRPNIYQVMHH 324
LT A+ + E + S + I +L ++P R I Q + H
Sbjct: 219 GETKQETLTNISAVNYDFDEEYFSNTSELAKDFIRRLLVKDPKRRMTIAQSLEH 272
>At3g29160 [T] KOG0583 Serine/threonine protein kinase
Length = 512
Score = 64.3 bits (155), Expect = 7e-10
Identities = 62/234 (26%), Positives = 109/234 (46%), Gaps = 35/234 (14%)
Query: 98 ELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKSLLDYMNNKLAT 157
++R E++ ++ L P+I++ Y+ + +I ++ME L DY+ K
Sbjct: 64 KVRREIKILR-LFMHPHIIRQYEVIETTS-------DIYVVMEYVKSGELFDYIVEK--G 113
Query: 158 KLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPI 217
+L E E + + + H ++HRD+K EN+L+D N K+ DFG ++
Sbjct: 114 RLQEDEARNFFQQIISGVEYCHR--NMVVHRDLKPENLLLDSRCNIKIADFGLSN----- 166
Query: 218 VSTHQDIAVLTNNIYVHT---TPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTT 274
V+ + ++ T +P Y +PE+I L + D+W+ G+ LY LL T
Sbjct: 167 --------VMRDGHFLKTSCGSPNYAAPEVIS--GKLYAGPEVDVWSCGVILYALLCGTL 216
Query: 275 PFE---LTGQF-AILHSKYEIPQNGYSSKLINLIIIMLAENPSLRPNIYQVMHH 324
PF+ + F I Y +P + SS+ +LI ML +P R I ++ H
Sbjct: 217 PFDDENIPNLFKKIKGGIYTLPSH-LSSEARDLIPRMLIVDPVKRITIPEIRQH 269
>At3g10660 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 646
Score = 64.3 bits (155), Expect = 7e-10
Identities = 66/252 (26%), Positives = 108/252 (42%), Gaps = 42/252 (16%)
Query: 86 KRVIVPDENGLNELRNEVETMKQLRGSPNIVQY---YDSNASRHPDGSPGFEILLLMELC 142
KR ++ DE+ + ++R E++ M L G PN++ Y+ + H L+MELC
Sbjct: 219 KRKLLTDED-VEDVRREIQIMHHLAGHPNVISIKGAYEDVVAVH----------LVMELC 267
Query: 143 PKKSLLDYMNNKLATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLV---DK 199
L D + + TE + ++ + + H L ++HRD+K EN L ++
Sbjct: 268 SGGELFDRIIQR--GHYTERKAAELARTIVGVLEACHSLG--VMHRDLKPENFLFVSREE 323
Query: 200 DDNFKLCDFGSTSMCFPIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDI 259
D K DFG SM F D+ +P Y +PE++ +SD+
Sbjct: 324 DSLLKTIDFG-LSMFFKPDEVFTDVV---------GSPYYVAPEVLRKR----YGPESDV 369
Query: 260 WALGIFLYKLLFYTTPFELTGQFAI----LHSKYEI---PQNGYSSKLINLIIIMLAENP 312
W+ G+ +Y LL PF + I LH + P S +L+ ML +P
Sbjct: 370 WSAGVIVYILLSGVPPFWAETEQGIFEQVLHGDLDFSSDPWPSISESAKDLVRKMLVRDP 429
Query: 313 SLRPNIYQVMHH 324
R +QV+ H
Sbjct: 430 KRRLTAHQVLCH 441
>At2g34180 [T] KOG0583 Serine/threonine protein kinase
Length = 502
Score = 64.3 bits (155), Expect = 7e-10
Identities = 76/302 (25%), Positives = 131/302 (43%), Gaps = 44/302 (14%)
Query: 30 SPNT-QVVVGTHRCEILEHLAEGGFANIYKVKFLELTNEMDAGI--DSKLLKAGDIACLK 86
SP T Q + + EI + L G FA +Y + + ++ + K++K+G +K
Sbjct: 44 SPRTPQGSILMDKYEIGKLLGHGSFAKVYLARNIHSGEDVAIKVIDKEKIVKSGLAGHIK 103
Query: 87 RVIVPDENGLNELRNEVETMKQLRGSPNIVQYYDSNASRHPDGSPGFEILLLMELCPKKS 146
R E+ ++++R P IV + A++ +I ++ME
Sbjct: 104 R--------------EISILRRVR-HPYIVHLLEVMATKT-------KIYIVMEYVRGGE 141
Query: 147 LLDYMNNKLATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLC 206
L N +L E + + +++A H + HRD+K+EN+L+D N K+
Sbjct: 142 LY---NTVARGRLREGTARRYFQQLISSVAFCH--SRGVYHRDLKLENLLLDDKGNVKVS 196
Query: 207 DFGSTSMCFPIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFL 266
DFG +VS + TP Y +PE+ L R K+DIW+ G+ L
Sbjct: 197 DFG-----LSVVSEQLKQEGICQTFC--GTPAYLAPEV--LTRKGYEGAKADIWSCGVIL 247
Query: 267 YKLLFYTTPFE----LTGQFAILHSKYEIPQNGYSSKLINLIIIMLAENPSLRPNIYQVM 322
+ L+ PF+ L I +++ P+ +S +L L+ ML NP R I ++M
Sbjct: 248 FVLMAGYLPFDDKNILVMYTKIYKGQFKCPK-WFSPELARLVTRMLDTNPDTRITIPEIM 306
Query: 323 HH 324
H
Sbjct: 307 KH 308
>YDR122w [T] KOG0583 Serine/threonine protein kinase
Length = 1064
Score = 63.9 bits (154), Expect = 9e-10
Identities = 70/298 (23%), Positives = 133/298 (44%), Gaps = 39/298 (13%)
Query: 43 EILEHLAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACL--KRVIVPDENGLNELR 100
E +E + G + K TNE+ A K++ A L ++++ P +N + L
Sbjct: 121 EFVETVGAGSMGKVKLAKH-RYTNEVCA---VKIVNRATKAFLHKEQMLPPPKNEQDVLE 176
Query: 101 NEVETMKQL-RGSPNIVQYYDSNASRHPDGSPGFEIL-------LLMELCPKKSLLDYMN 152
+ + K++ R I + HP FE+ +L E LLDY+
Sbjct: 177 RQKKLEKEISRDKRTIREASLGQILYHPHICRLFEMCTLSNHFYMLFEYVSGGQLLDYII 236
Query: 153 NKLATKLTEAEILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTS 212
+ E + K +++A+ +H ++HRD+KIEN+++ K+ DFG ++
Sbjct: 237 QH--GSIREHQARKFARGIASALIYLH--ANNIVHRDLKIENIMISDSSEIKIIDFGLSN 292
Query: 213 MCFPIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRCLP-INEKSDIWALGIFLYKLLF 271
I + + + ++Y + +PE++ + P + D+W+ G+ L+ L+
Sbjct: 293 ----IYDSRKQLHTFCGSLY------FAAPELL---KANPYTGPEVDVWSFGVVLFVLVC 339
Query: 272 YTTPFELTGQFAILH-----SKYEIPQNGYSSKLINLIIIMLAENPSLRPNIYQVMHH 324
PF+ ++LH K E PQ+ S ++I+L+ ML +P R + QV+ H
Sbjct: 340 GKVPFD-DENSSVLHEKIKQGKVEYPQH-LSIEVISLLSKMLVVDPKRRATLKQVVEH 395
>HsM4826916 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 603
Score = 63.9 bits (154), Expect = 9e-10
Identities = 72/285 (25%), Positives = 128/285 (44%), Gaps = 51/285 (17%)
Query: 48 LAEGGFANIYKVKFLELTNEMDAGIDSKLLKAGDIACLKRVIVPDENGLNELRNEVETMK 107
L +GGFA +++ DA D+K + AG I VP L + E +M+
Sbjct: 59 LGKGGFAKCFEIS--------DA--DTKEVFAGKI-------VPKSLLLKPHQREKMSME 101
Query: 108 QLRGSPNIVQYYDSNASRHPDGSPGFE-----ILLLMELCPKKSLLDYMNNKLATKLTEA 162
+ + S A +H G GF + +++ELC ++SLL+ + A LTE
Sbjct: 102 --------ISIHRSLAHQHVVGFHGFFEDNDFVFVVLELCRRRSLLEPHKRRKA--LTEP 151
Query: 163 EILKIMYDVSNAIAQMHYLPTPLIHRDIKIENVLVDKDDNFKLCDFGSTSMCFPIVSTHQ 222
E + + +H +IHRD+K+ N+ +++D K+ DFG + +
Sbjct: 152 EARYYLRQIVLGCQYLHR--NRVIHRDLKLGNLFLNEDLEVKIGDFGLATKVEYDGERKK 209
Query: 223 DIAVLTNNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGIFLYKLLFYTTPFELT--- 279
+ TP Y +PE++ + + D+W++G +Y LL PFE +
Sbjct: 210 TLC---------GTPNYIAPEVLSKKE---HSFEVDVWSIGCIMYTLLVGKPPFETSCLK 257
Query: 280 -GQFAILHSKYEIPQNGYSSKLINLIIIMLAENPSLRPNIYQVMH 323
I ++Y IP++ + +LI ML +P+ RP I ++++
Sbjct: 258 ETYLRIKKNEYSIPKH-INPVAASLIQKMLQTDPTARPTINELLN 301
>HsM4506099 [T] KOG0984 Mitogen-activated protein kinase (MAPK) kinase
MKK3/MKK6
Length = 318
Score = 63.9 bits (154), Expect = 9e-10
Identities = 49/200 (24%), Positives = 92/200 (45%), Gaps = 21/200 (10%)
Query: 134 EILLLMELCPKKSLLDYMNNKLATK---LTEAEILKIMYDVSNAIAQMHYLPTPLIHRDI 190
++ + MEL LD K+ K + E + +I + A+ +H +IHRD+
Sbjct: 106 DVWICMELMDTS--LDKFYRKVLDKNMTIPEDILGEIAVSIVRALEHLHS-KLSVIHRDV 162
Query: 191 KIENVLVDKDDNFKLCDFGSTSMCFPIVSTHQDIAVLTNNIYVHTTPQYRSPEMIDLYRC 250
K NVL++K+ + K+CDFG + V+ D + P+ +PE+
Sbjct: 163 KPSNVLINKEGHVKMCDFGISGYLVDSVAKTMDAGCKP-----YMAPERINPEL----NQ 213
Query: 251 LPINEKSDIWALGIFLYKLLFYTTPFELTG------QFAILHSKYEIPQNGYSSKLINLI 304
N KSD+W+LGI + ++ P+E G + + ++P + +S + ++
Sbjct: 214 KGYNVKSDVWSLGITMIEMAILRFPYESWGTPFQQLKQVVEEPSPQLPADRFSPEFVDFT 273
Query: 305 IIMLAENPSLRPNIYQVMHH 324
L +NP+ R + ++M H
Sbjct: 274 AQCLRKNPAERMSYLELMEH 293
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.315 0.132 0.377
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 44,911,301
Number of Sequences: 60738
Number of extensions: 1905049
Number of successful extensions: 8604
Number of sequences better than 1.0e-05: 740
Number of HSP's better than 0.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 722
Number of HSP's that attempted gapping in prelim test: 7625
Number of HSP's gapped (non-prelim): 833
length of query: 814
length of database: 30,389,216
effective HSP length: 115
effective length of query: 699
effective length of database: 23,404,346
effective search space: 16359637854
effective search space used: 16359637854
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.5 bits)