ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI5184 good U KOG0860 Intracellular trafficking, secretion, and vesicular transport Synaptobrevin/VAMP-like protein
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI5184 1800266 1799574 -231
(231 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YLR093c [U] KOG0860 Synaptobrevin/VAMP-like protein 181 6e-46
At5g11150 [U] KOG0859 Synaptobrevin/VAMP-like protein 57 2e-08
7303846 [U] KOG0859 Synaptobrevin/VAMP-like protein 57 2e-08
At4g32150 [U] KOG0859 Synaptobrevin/VAMP-like protein 55 6e-08
At2g25340 [U] KOG0859 Synaptobrevin/VAMP-like protein 55 8e-08
7303772 [U] KOG0860 Synaptobrevin/VAMP-like protein 55 1e-07
CE18252 [U] KOG0860 Synaptobrevin/VAMP-like protein 54 1e-07
At5g22360 [U] KOG0859 Synaptobrevin/VAMP-like protein 54 2e-07
At2g32670 [U] KOG0859 Synaptobrevin/VAMP-like protein 54 2e-07
Hs4759300 [U] KOG0860 Synaptobrevin/VAMP-like protein 53 3e-07
At3g54300 [U] KOG0859 Synaptobrevin/VAMP-like protein 53 3e-07
Hs7657675 [U] KOG0860 Synaptobrevin/VAMP-like protein 53 4e-07
Hs9257251 [U] KOG0860 Synaptobrevin/VAMP-like protein 52 9e-07
Hs7657673 [U] KOG0860 Synaptobrevin/VAMP-like protein 52 9e-07
At1g04760 [U] KOG0859 Synaptobrevin/VAMP-like protein 52 9e-07
YOR327c [U] KOG0860 Synaptobrevin/VAMP-like protein 51 1e-06
At2g33120 [U] KOG0859 Synaptobrevin/VAMP-like protein 51 1e-06
Hs14736500 [U] KOG0860 Synaptobrevin/VAMP-like protein 51 2e-06
SPAC6G9.11 [U] KOG0860 Synaptobrevin/VAMP-like protein 50 2e-06
Hs4507863 [U] KOG0860 Synaptobrevin/VAMP-like protein 50 3e-06
Hs14043026 [U] KOG0860 Synaptobrevin/VAMP-like protein 50 3e-06
At1g04750 [U] KOG0859 Synaptobrevin/VAMP-like protein 49 4e-06
7292118 [U] KOG0860 Synaptobrevin/VAMP-like protein 49 4e-06
YAL030w [U] KOG0860 Synaptobrevin/VAMP-like protein 49 6e-06
>YLR093c [U] KOG0860 Synaptobrevin/VAMP-like protein
Length = 253
Score = 181 bits (460), Expect = 6e-46
Identities = 100/230 (43%), Positives = 144/230 (62%), Gaps = 21/230 (9%)
Query: 1 MKRYSVSYVEVWDGDRVLSSWYDSKDENNSKYGSTDKGRADQKAVFHRLIGDMVIRTVVN 60
MKR++VSYVEV +SS + +N + T +FH LI DMV+ VV
Sbjct: 1 MKRFNVSYVEVIKNGETISSCFQPFQKNENYGTITSANEQITPVIFHNLIMDMVLPKVVP 60
Query: 61 LPGNKVTKTSIDLIEGYDCYYTTAENNK--VLICFVKEEVPKFLPLRLLSELKCL-NNDN 117
+ GNKVTK S++LI+G+DC+Y+T +++ V +CF ++PK LP+R+LS L+ +N
Sbjct: 61 IKGNKVTKMSMNLIDGFDCFYSTDDHDPKTVYVCFTLVDMPKILPIRILSGLQEYESNAT 120
Query: 118 DEYLKSNIDNQLDKFHEELLSYRTE--------------GQQTAA----STEEELQNIIA 159
+E L S++ LD FHEEL+ YR + GQ T + +TE++++++I
Sbjct: 121 NELLSSHVGQILDSFHEELVEYRNQTLNSSGNGQSSNGNGQNTISDIGDATEDQIKDVIQ 180
Query: 160 IMNDNIDKFLQRQERISLLVDNTNQLNENSFKFQRKSSKIMRKMWWNNVK 209
IMNDNIDKFL+RQER+SLLVD T+QLN +S KF+RK+ I MWW VK
Sbjct: 181 IMNDNIDKFLERQERVSLLVDKTSQLNSSSNKFRRKAVNIKEIMWWQKVK 230
>At5g11150 [U] KOG0859 Synaptobrevin/VAMP-like protein
Length = 221
Score = 57.4 bits (137), Expect = 2e-08
Identities = 24/57 (42%), Positives = 37/57 (64%)
Query: 153 ELQNIIAIMNDNIDKFLQRQERISLLVDNTNQLNENSFKFQRKSSKIMRKMWWNNVK 209
E+ + +M +NIDK L R ER+ LLVD T + N+F+F++++ + MWW NVK
Sbjct: 134 EMSQVRNVMIENIDKVLDRGERLELLVDKTENMQGNTFRFRKQARRYRTIMWWRNVK 190
>7303846 [U] KOG0859 Synaptobrevin/VAMP-like protein
Length = 218
Score = 57.0 bits (136), Expect = 2e-08
Identities = 37/160 (23%), Positives = 73/160 (45%), Gaps = 12/160 (7%)
Query: 59 VNLPGNKVTKTSIDLIEGYDCYYTTAENNKVLICFVKEEVPKFLPLRLLSELK-----CL 113
+ + +K+T T D + Y C EN V +C E + L+++K
Sbjct: 36 IGVHNHKMTYTHGDYLIHYTC-----ENKLVYMCITDNEFERSRAFLFLADIKQKFIQTY 90
Query: 114 NNDNDEYLKSNIDNQLDKFHEELLSYRTEGQQ--TAASTEEELQNIIAIMNDNIDKFLQR 171
+ +++ + K + + Y ++ ++ T + ++ + IM NID R
Sbjct: 91 GLQVATAIAYSMNTEFSKILAQQMVYFSQSREVDTISRVHGQIDELKDIMVKNIDSLRDR 150
Query: 172 QERISLLVDNTNQLNENSFKFQRKSSKIMRKMWWNNVKFY 211
E++ LLV+ T L+ NS F++ S + R+M+W N++ Y
Sbjct: 151 GEKLELLVNKTENLSNNSVAFRKASRNLARQMFWKNIRVY 190
>At4g32150 [U] KOG0859 Synaptobrevin/VAMP-like protein
Length = 219
Score = 55.5 bits (132), Expect = 6e-08
Identities = 22/57 (38%), Positives = 36/57 (62%)
Query: 153 ELQNIIAIMNDNIDKFLQRQERISLLVDNTNQLNENSFKFQRKSSKIMRKMWWNNVK 209
E+ + +M +NIDK L R ER+ LLVD T + N+F+F++++ + +WW N K
Sbjct: 133 EMNQVRGVMIENIDKVLDRGERLELLVDKTANMQGNTFRFRKQARRFRSNVWWRNCK 189
>At2g25340 [U] KOG0859 Synaptobrevin/VAMP-like protein
Length = 219
Score = 55.1 bits (131), Expect = 8e-08
Identities = 36/163 (22%), Positives = 74/163 (45%), Gaps = 23/163 (14%)
Query: 61 LPGNKVTKTSIDLIEGYDCYYTTAENNKVLICFVKEEVPKFLPLRLLSEL---------K 111
+PGN + S + ++ + ++C E+ + +P L ++ +
Sbjct: 36 IPGNGDSHVSYS--QDRYVFHVKRTDGLTVLCMADEDAGRRIPFSFLEDIHQRFVRTYGR 93
Query: 112 CLNND-----NDEYLKSNIDNQLDKFHEELLSYRTEGQQTAASTEEELQNIIAIMNDNID 166
+++ NDE+ S + NQ +++ T + + E+ + +M +NID
Sbjct: 94 AIHSAQAYAMNDEF--SRVLNQQIEYYSN-----DPNADTISRIKGEMNQVRDVMIENID 146
Query: 167 KFLQRQERISLLVDNTNQLNENSFKFQRKSSKIMRKMWWNNVK 209
L R ER+ LLVD T + N+F+F++++ + +WW N K
Sbjct: 147 NILDRGERLELLVDKTANMQGNTFRFRKQTRRFNNTVWWRNCK 189
>7303772 [U] KOG0860 Synaptobrevin/VAMP-like protein
Length = 129
Score = 54.7 bits (130), Expect = 1e-07
Identities = 20/66 (30%), Positives = 43/66 (64%)
Query: 144 QQTAASTEEELQNIIAIMNDNIDKFLQRQERISLLVDNTNQLNENSFKFQRKSSKIMRKM 203
Q+ T+ ++ ++ IM N++K L+R +++S L + +QL + + +F++++ K+ RK
Sbjct: 22 QKKLQQTQAKVDEVVGIMRVNVEKVLERDQKLSELGERADQLEQGASQFEQQAGKLKRKQ 81
Query: 204 WWNNVK 209
WW N+K
Sbjct: 82 WWANMK 87
>CE18252 [U] KOG0860 Synaptobrevin/VAMP-like protein
Length = 109
Score = 54.3 bits (129), Expect = 1e-07
Identities = 23/66 (34%), Positives = 41/66 (61%), Gaps = 4/66 (6%)
Query: 144 QQTAASTEEELQNIIAIMNDNIDKFLQRQERISLLVDNTNQLNENSFKFQRKSSKIMRKM 203
QQT A +E ++ IM N++K L+R +++S L D + L E + +F++ ++ + RK
Sbjct: 25 QQTQAQVDE----VVGIMKVNVEKVLERDQKLSQLDDRADALQEGASQFEKSAATLKRKY 80
Query: 204 WWNNVK 209
WW N+K
Sbjct: 81 WWKNIK 86
>At5g22360 [U] KOG0859 Synaptobrevin/VAMP-like protein
Length = 221
Score = 53.9 bits (128), Expect = 2e-07
Identities = 22/57 (38%), Positives = 39/57 (67%)
Query: 153 ELQNIIAIMNDNIDKFLQRQERISLLVDNTNQLNENSFKFQRKSSKIMRKMWWNNVK 209
E+ I ++M +NI+K ++R +RI LLVD T + ++SF F+++S ++ R +W N K
Sbjct: 134 EVSEIRSVMVENIEKIMERGDRIELLVDKTATMQDSSFHFRKQSKRLRRALWMKNAK 190
>At2g32670 [U] KOG0859 Synaptobrevin/VAMP-like protein
Length = 220
Score = 53.5 bits (127), Expect = 2e-07
Identities = 24/62 (38%), Positives = 38/62 (60%)
Query: 148 ASTEEELQNIIAIMNDNIDKFLQRQERISLLVDNTNQLNENSFKFQRKSSKIMRKMWWNN 207
A + ++ + +M +NI+K L R E+I LLVD T L + F+ + +KI RKMW+ N
Sbjct: 132 AKVKAQVTEVKGVMMENIEKVLDRGEKIELLVDKTENLRSQAQDFRTQGTKIRRKMWFEN 191
Query: 208 VK 209
+K
Sbjct: 192 MK 193
>Hs4759300 [U] KOG0860 Synaptobrevin/VAMP-like protein
Length = 100
Score = 53.1 bits (126), Expect = 3e-07
Identities = 21/71 (29%), Positives = 40/71 (55%)
Query: 141 TEGQQTAASTEEELQNIIAIMNDNIDKFLQRQERISLLVDNTNQLNENSFKFQRKSSKIM 200
T + T+ ++ ++ IM N+DK L+R +++S L D + L + +F+ ++K+
Sbjct: 9 TGSNRRLQQTQNQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFETSAAKLK 68
Query: 201 RKMWWNNVKFY 211
RK WW N K +
Sbjct: 69 RKYWWKNCKMW 79
>At3g54300 [U] KOG0859 Synaptobrevin/VAMP-like protein
Length = 240
Score = 53.1 bits (126), Expect = 3e-07
Identities = 28/89 (31%), Positives = 46/89 (51%), Gaps = 3/89 (3%)
Query: 124 NIDNQLDKFHEELLSY---RTEGQQTAASTEEELQNIIAIMNDNIDKFLQRQERISLLVD 180
N+D + +E + Y E + + ++ + IM DNI+K L R E+I LLVD
Sbjct: 124 NLDREFGPILKEHMQYCMSHPEEMSKLSKLKAQITEVKGIMMDNIEKVLDRGEKIELLVD 183
Query: 181 NTNQLNENSFKFQRKSSKIMRKMWWNNVK 209
T L + FQR+ ++ RKMW +++
Sbjct: 184 KTENLQFQADSFQRQGRQLRRKMWLQSLQ 212
>Hs7657675 [U] KOG0860 Synaptobrevin/VAMP-like protein
Length = 116
Score = 52.8 bits (125), Expect = 4e-07
Identities = 24/66 (36%), Positives = 40/66 (60%), Gaps = 4/66 (6%)
Query: 144 QQTAASTEEELQNIIAIMNDNIDKFLQRQERISLLVDNTNQLNENSFKFQRKSSKIMRKM 203
QQT A +E ++ IM N+DK L+R +++S L D + L + +F+ ++K+ RK
Sbjct: 33 QQTQAQVDE----VVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFETSAAKLKRKY 88
Query: 204 WWNNVK 209
WW N+K
Sbjct: 89 WWKNLK 94
>Hs9257251 [U] KOG0860 Synaptobrevin/VAMP-like protein
Length = 116
Score = 51.6 bits (122), Expect = 9e-07
Identities = 24/66 (36%), Positives = 39/66 (58%), Gaps = 4/66 (6%)
Query: 144 QQTAASTEEELQNIIAIMNDNIDKFLQRQERISLLVDNTNQLNENSFKFQRKSSKIMRKM 203
QQT A EE ++ I+ N+DK L+R +++S L D + L + +F+ ++K+ RK
Sbjct: 35 QQTQAQVEE----VVDIIRVNVDKVLERDQKLSELDDRADALQAGASQFESSAAKLKRKY 90
Query: 204 WWNNVK 209
WW N K
Sbjct: 91 WWKNCK 96
>Hs7657673 [U] KOG0860 Synaptobrevin/VAMP-like protein
Length = 118
Score = 51.6 bits (122), Expect = 9e-07
Identities = 24/66 (36%), Positives = 39/66 (58%), Gaps = 4/66 (6%)
Query: 144 QQTAASTEEELQNIIAIMNDNIDKFLQRQERISLLVDNTNQLNENSFKFQRKSSKIMRKM 203
QQT A EE ++ I+ N+DK L+R +++S L D + L + +F+ ++K+ RK
Sbjct: 35 QQTQAQVEE----VVDIIRVNVDKVLERDQKLSELDDRADALQAGASQFESSAAKLKRKY 90
Query: 204 WWNNVK 209
WW N K
Sbjct: 91 WWKNCK 96
>At1g04760 [U] KOG0859 Synaptobrevin/VAMP-like protein
Length = 220
Score = 51.6 bits (122), Expect = 9e-07
Identities = 37/137 (27%), Positives = 61/137 (44%), Gaps = 13/137 (9%)
Query: 84 AENNKVLICFVKEEVPKFLPLRLLSELKCLNNDNDEYLKSNIDN-QLDKFHEELLSYRTE 142
A+N V E + +P+ L +K + N Y + + ++E S E
Sbjct: 59 ADNGFTYCVVVIESAGRQIPMAFLERVK--EDFNKRYGGGKASTAKANSLNKEFGSKLKE 116
Query: 143 GQQTAASTEEELQNII----------AIMNDNIDKFLQRQERISLLVDNTNQLNENSFKF 192
Q A EE+ + +M +NI+K L R E+I LLVD T L + F
Sbjct: 117 HMQYCADHPEEISKLSKVKAQVTEVKGVMMENIEKVLDRGEKIELLVDKTENLRSQAQDF 176
Query: 193 QRKSSKIMRKMWWNNVK 209
+ + +K+ RK+W+ N+K
Sbjct: 177 RTQGTKMKRKLWFENMK 193
>YOR327c [U] KOG0860 Synaptobrevin/VAMP-like protein
Length = 115
Score = 51.2 bits (121), Expect = 1e-06
Identities = 20/66 (30%), Positives = 42/66 (63%)
Query: 144 QQTAASTEEELQNIIAIMNDNIDKFLQRQERISLLVDNTNQLNENSFKFQRKSSKIMRKM 203
Q A+ +E+ + + IM DNI+K +R ER++ + D + L ++ F+R ++++ ++M
Sbjct: 25 QNKTAALRQEIDDTVGIMRDNINKVAERGERLTSIEDKADNLAISAQGFKRGANRVRKQM 84
Query: 204 WWNNVK 209
WW ++K
Sbjct: 85 WWKDLK 90
>At2g33120 [U] KOG0859 Synaptobrevin/VAMP-like protein
Length = 221
Score = 51.2 bits (121), Expect = 1e-06
Identities = 22/62 (35%), Positives = 38/62 (60%)
Query: 148 ASTEEELQNIIAIMNDNIDKFLQRQERISLLVDNTNQLNENSFKFQRKSSKIMRKMWWNN 207
A + ++ + +M +NI+K L R E+I LLVD T L + F+ + +++ RKMW+ N
Sbjct: 132 AKVKAQVSEVKGVMMENIEKVLDRGEKIELLVDKTENLRSQAQDFRTQGTQMRRKMWFQN 191
Query: 208 VK 209
+K
Sbjct: 192 MK 193
>Hs14736500 [U] KOG0860 Synaptobrevin/VAMP-like protein
Length = 140
Score = 50.8 bits (120), Expect = 2e-06
Identities = 19/59 (32%), Positives = 36/59 (60%)
Query: 151 EEELQNIIAIMNDNIDKFLQRQERISLLVDNTNQLNENSFKFQRKSSKIMRKMWWNNVK 209
+ ++ +I +M +NI K ++R ER+ L D + L++N+ F +S ++ R+MWW K
Sbjct: 56 QNQVDEVIDVMQENITKVIERGERLDELQDKSESLSDNATAFSNRSKQLRRQMWWRGCK 114
>SPAC6G9.11 [U] KOG0860 Synaptobrevin/VAMP-like protein
Length = 121
Score = 50.4 bits (119), Expect = 2e-06
Identities = 22/69 (31%), Positives = 44/69 (62%), Gaps = 1/69 (1%)
Query: 141 TEGQQTAASTEEELQNIIAIMNDNIDKFLQRQERISLLVDNTNQLNENSFKFQRKSSKIM 200
T +TAA ++++ + + IM +NI K +R ER+ L D T+ L ++ F+R ++++
Sbjct: 27 TPNMKTAA-IQQQIDDTVGIMRENISKVSERGERLDSLQDKTDNLAVSAQGFRRGANRVR 85
Query: 201 RKMWWNNVK 209
+KMWW +++
Sbjct: 86 KKMWWKDMR 94
>Hs4507863 [U] KOG0860 Synaptobrevin/VAMP-like protein
Length = 141
Score = 50.1 bits (118), Expect = 3e-06
Identities = 19/59 (32%), Positives = 36/59 (60%)
Query: 151 EEELQNIIAIMNDNIDKFLQRQERISLLVDNTNQLNENSFKFQRKSSKIMRKMWWNNVK 209
+ ++ +I +M +NI K ++R ER+ L D + L++N+ F +S ++ R+MWW K
Sbjct: 57 QNQVDEVIDVMPENITKVIERGERLDELQDKSESLSDNATAFSNRSKQLRRQMWWRGCK 115
>Hs14043026 [U] KOG0860 Synaptobrevin/VAMP-like protein
Length = 100
Score = 49.7 bits (117), Expect = 3e-06
Identities = 22/67 (32%), Positives = 34/67 (49%)
Query: 143 GQQTAASTEEELQNIIAIMNDNIDKFLQRQERISLLVDNTNQLNENSFKFQRKSSKIMRK 202
G + + E++ + IM N+++ L R E + L + T L S F+ S K+ RK
Sbjct: 9 GNDRVRNLQSEVEGVKNIMTQNVERILARGENLEHLRNKTEDLEATSEHFKTTSQKVARK 68
Query: 203 MWWNNVK 209
WW NVK
Sbjct: 69 FWWKNVK 75
>At1g04750 [U] KOG0859 Synaptobrevin/VAMP-like protein
Length = 219
Score = 49.3 bits (116), Expect = 4e-06
Identities = 22/62 (35%), Positives = 36/62 (57%)
Query: 148 ASTEEELQNIIAIMNDNIDKFLQRQERISLLVDNTNQLNENSFKFQRKSSKIMRKMWWNN 207
A + ++ + +M +NI+K L R E+I LLVD T L + F+ +++ RKMW N
Sbjct: 132 AKVKAQVSEVKGVMMENIEKVLDRGEKIELLVDKTENLRSQAQDFRTTGTQMRRKMWLQN 191
Query: 208 VK 209
+K
Sbjct: 192 MK 193
>7292118 [U] KOG0860 Synaptobrevin/VAMP-like protein
Length = 192
Score = 49.3 bits (116), Expect = 4e-06
Identities = 19/66 (28%), Positives = 40/66 (59%)
Query: 144 QQTAASTEEELQNIIAIMNDNIDKFLQRQERISLLVDNTNQLNENSFKFQRKSSKIMRKM 203
Q+ T+ ++ ++ IM N++K L+R ++S L D + L + + +F++++ K+ RK
Sbjct: 48 QKRLQQTQAQVDEVVDIMRTNVEKVLERDSKLSELDDRADALQQGASQFEQQAGKLKRKF 107
Query: 204 WWNNVK 209
W N+K
Sbjct: 108 WLQNLK 113
>YAL030w [U] KOG0860 Synaptobrevin/VAMP-like protein
Length = 117
Score = 48.9 bits (115), Expect = 6e-06
Identities = 20/77 (25%), Positives = 44/77 (56%)
Query: 133 HEELLSYRTEGQQTAASTEEELQNIIAIMNDNIDKFLQRQERISLLVDNTNQLNENSFKF 192
H+E + + A + E+ + + IM DNI+K +R ER++ + D + L ++ F
Sbjct: 15 HDEERPQNVQSKSRTAELQAEIDDTVGIMRDNINKVAERGERLTSIEDKADNLAVSAQGF 74
Query: 193 QRKSSKIMRKMWWNNVK 209
+R ++++ + MW+ ++K
Sbjct: 75 KRGANRVRKAMWYKDLK 91
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.316 0.133 0.385
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,979,842
Number of Sequences: 60738
Number of extensions: 557812
Number of successful extensions: 2136
Number of sequences better than 1.0e-05: 24
Number of HSP's better than 0.0 without gapping: 24
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 2109
Number of HSP's gapped (non-prelim): 24
length of query: 231
length of database: 30,389,216
effective HSP length: 103
effective length of query: 128
effective length of database: 24,133,202
effective search space: 3089049856
effective search space used: 3089049856
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)