ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI5351 good L KOG2248 Replication, recombination and repair 3'-5' exonuclease
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI5351 1854593 1856026 478
(478 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YLR107w [L] KOG2248 3'-5' exonuclease 371 e-102
SPAC1782.08c [L] KOG2248 3'-5' exonuclease 166 5e-41
Hs22050764 [L] KOG2248 3'-5' exonuclease 140 4e-33
Hs14764743 [L] KOG2248 3'-5' exonuclease 139 9e-33
Hs22050790 [L] KOG2248 3'-5' exonuclease 135 1e-31
Hs22050759 [L] KOG2248 3'-5' exonuclease 116 6e-26
7290209 [L] KOG2248 3'-5' exonuclease 114 2e-25
YGR276c [L] KOG2248 3'-5' exonuclease 114 3e-25
7301627 [L] KOG2248 3'-5' exonuclease 114 3e-25
CE25823 [L] KOG2248 3'-5' exonuclease 113 5e-25
CE24469 [L] KOG2248 3'-5' exonuclease 113 7e-25
Hs22047614 [L] KOG2248 3'-5' exonuclease 112 2e-24
SPAC637.09 [L] KOG2248 3'-5' exonuclease 98 3e-20
ECU07g0380 [L] KOG2248 3'-5' exonuclease 96 2e-19
At3g15080 [L] KOG2249 3'-5' exonuclease 86 2e-16
Hs13569913 [L] KOG2248 3'-5' exonuclease 78 3e-14
At3g50100 [L] KOG2248 3'-5' exonuclease 76 1e-13
CE07923 [L] KOG2248 3'-5' exonuclease 72 1e-12
7295335 [L] KOG2248 3'-5' exonuclease 72 1e-12
7294419 [L] KOG2249 3'-5' exonuclease 72 2e-12
SPBC1604.09c [L] KOG2249 3'-5' exonuclease 70 5e-12
YOL080c [L] KOG2249 3'-5' exonuclease 70 9e-12
At5g25800 [L] KOG2248 3'-5' exonuclease 68 3e-11
At5g05540 [L] KOG2248 3'-5' exonuclease 67 6e-11
Hs9966857_2 [L] KOG2249 3'-5' exonuclease 65 2e-10
Hs13569960 [L] KOG2249 3'-5' exonuclease 65 2e-10
Hs21362094 [L] KOG2249 3'-5' exonuclease 65 3e-10
CE19046 [L] KOG2249 3'-5' exonuclease 64 4e-10
Hs22057667 [L] KOG2249 3'-5' exonuclease 64 5e-10
HsM12232443 [L] KOG2249 3'-5' exonuclease 58 3e-08
CE01269 [L] KOG1275 PAB-dependent poly(A) ribonuclease subunit PAN2 57 8e-08
YGL094c [L] KOG1275 PAB-dependent poly(A) ribonuclease subunit PAN2 55 2e-07
SPAC22G7.04 [L] KOG1275 PAB-dependent poly(A) ribonuclease subun... 53 1e-06
Hs6857800 [L] KOG2249 3'-5' exonuclease 52 2e-06
7303975 [L] KOG1275 PAB-dependent poly(A) ribonuclease subunit PAN2 52 2e-06
>YLR107w [L] KOG2248 3'-5' exonuclease
Length = 404
Score = 371 bits (953), Expect = e-102
Identities = 189/399 (47%), Positives = 273/399 (68%), Gaps = 19/399 (4%)
Query: 99 VLRPVDMKMQPAPYQDRVRVVQKIYTQLKRF----QSSSPHIIKASTIWEHEVAKIAKTR 154
+LRPVD+ QP +Q+R +++QK++ QL++ + ++ + + +T E VAK + +
Sbjct: 4 LLRPVDLVNQPLGFQERYKILQKLFKQLQKAYAHTKGTNIDLERLATRLEVHVAKNSLSG 63
Query: 155 QSYAFNASILLRDIVKYKGNLDK---TGKPKN----------NSSSLIQRSHVLQKLRSL 201
QSY FN SILLRD++KYKG+L K G+P N++S+ +S ++ L++L
Sbjct: 64 QSYKFNMSILLRDVLKYKGDLSKIKINGRPLKGAKPHLSSIGNANSITTKSKAMEALKAL 123
Query: 202 LLDEETLSRNGFFVK-MYDTDPINESESDYVECYRCETKFDVTKIMEPTVCRYHLQRKVY 260
+LD + L +NG+ VK M + + S Y C RC + F T IME T+CRYH +++Y
Sbjct: 124 ILDSKVLEKNGYIVKEMQNKTNDDNSTQLYAPCLRCSSNFKKTDIMEKTLCRYHPLKRIY 183
Query: 261 NRETKKREFPCCGASLESYSDISAGCMKAKNHVYKWENFTKLSSVVPFKSLVDIKGEENV 320
NR+TK ++PCCG + +S S + GC +HV++ E++ +L + F S DI G ENV
Sbjct: 184 NRDTKNHQYPCCGETTDSVSFLRLGCKTFFHHVFRGESYDELCKISKFSSTDDIDGVENV 243
Query: 321 LALDCEMAFTSKGYEMIRITIVDFWSSEVVYDKVIKPLGEIIDLNSKFSGIHHIDDT-AP 379
L+LDCEMAFTS GYEMIR+TIVDF++ + ++D VI+P+G+I+DLNS FSG+H ID T P
Sbjct: 244 LSLDCEMAFTSLGYEMIRLTIVDFFTGKTLFDHVIQPIGDIVDLNSDFSGVHEIDRTNCP 303
Query: 380 TIHEAEKCYICPSMINQNSILIGHGLDNDLRVMRIVHDKVIDTAVLYPAGKYKSSLKNLS 439
T EA ++ ++IN+NSILIGHGL+NDL VMR+ H+KVIDTA+LY K+K SLKNL+
Sbjct: 304 TYKEALDVFLSENLINKNSILIGHGLENDLNVMRLFHNKVIDTAILYSRTKFKVSLKNLA 363
Query: 440 FEILSRRIQGGEHDSSEDAIAAMDVIKKKLSIPLDKKSW 478
FE+LSR+IQ GEHDSS+DAIA MDV+K K+ I + W
Sbjct: 364 FEVLSRKIQNGEHDSSQDAIATMDVVKVKIGISPSQNKW 402
>SPAC1782.08c [L] KOG2248 3'-5' exonuclease
Length = 540
Score = 166 bits (421), Expect = 5e-41
Identities = 118/366 (32%), Positives = 188/366 (51%), Gaps = 35/366 (9%)
Query: 109 PAPYQDRVRVVQKIYTQLKRFQSSSPHIIKASTIWEHEVAKIAKTRQSYAFNASILLRDI 168
PA ++ R R+ +Y K S+ + + E + + A ++ Y+ + + +
Sbjct: 190 PAGHELRKRMTHLLYESYKDLGYSNAESSMLALLDEKNICETANSKMIYSSSCKSKILSL 249
Query: 169 VKYKGNLDKTGKPKNNSSSLIQRSHVLQKLRSLLLDEETLSRNGFFVKMYDTDPINESES 228
K PK N IQ S +KL SL+ EE L G+ + D P+N +
Sbjct: 250 KK---------APKKNE---IQGSTPDEKLESLVHSEEELILWGYNIG--DVAPVNPPD- 294
Query: 229 DYVECYRCETKFDVTKIMEPTVCRYHLQRKVYNRE--TKKREFPCCGASLESYSDISAGC 286
+ EC RC T+F + C YH + ++ K R + CCG S+GC
Sbjct: 295 ELRECDRCGTRFADPR----GPCTYHWGKLFREKQGGEKIRTYTCCGVK----EGDSSGC 346
Query: 287 MKAKNHVYKWENFTKLSSVVPFKSLVDIKGEENV--LALDCEMAFTSKGYEMIRITIVDF 344
+ NHV+K+ + L+SV PF L D + + ALDCE+ +T+ G E+ R+T+V
Sbjct: 347 IIEDNHVFKYRHLPYLASVHPFSYLPDSTNSKQLSHCALDCELCYTTNGMELARLTVVA- 405
Query: 345 WSSEVVYDKVIKPLGEIIDLNSKFSGIHHIDDTAPTIHEAEKCYICPSMI--NQNSILIG 402
++ D IKP G+I+ LN++FSGIH + I ++ YI + N+N+ILIG
Sbjct: 406 -KESIIMDVFIKPKGKILSLNTRFSGIHDAKELESGI-TMDQMYIKIKELGMNKNTILIG 463
Query: 403 HGLDNDLRVMRIVHDKVIDTAVLYPAGK---YKSSLKNLSFEILSRRIQGGEHDSSEDAI 459
HGL+NDL MR++H +VIDTA+L+ + ++ SLK L+ + L IQ HDS EDA+
Sbjct: 464 HGLENDLNAMRLIHKRVIDTALLFTHARGPPFRYSLKYLTKKYLGTTIQTSTHDSEEDAV 523
Query: 460 AAMDVI 465
+A+ ++
Sbjct: 524 SALQLV 529
>Hs22050764 [L] KOG2248 3'-5' exonuclease
Length = 506
Score = 140 bits (353), Expect = 4e-33
Identities = 94/300 (31%), Positives = 152/300 (50%), Gaps = 25/300 (8%)
Query: 189 IQRSHVLQKLRSLLLDEETLSRNGF---------FVKMYDTDPINESESDYVECYRCETK 239
+ R+ + +L+ LL ++ L NG+ ++ +S C RC T+
Sbjct: 192 LSRAALYSRLQEFLLTQDQLKENGYPFPHPERPGGAVLFTGQGKGPGDSSCRVCCRCGTE 251
Query: 240 FDVT---KIMEPTVCRYHLQRKVYNRETKKR--EFPCCGASLESYSDISAGCMKAKNHVY 294
+ V+ + + +C YH R ++ R ++ CC A+ S GC AK HV
Sbjct: 252 YLVSSSGRCVRDQLCYYHWGRVRSSQVAGGRVSQYTCCAAAPGS-----VGCQVAKQHVR 306
Query: 295 KWENFTKLSSVVPFKSLVDIKGEENVLALDCEMAFTSKGYEMIRITIVDFWSSEVVYDKV 354
+ V FK + + ALDCEM +T+ G E+ R+T+VD VVYD
Sbjct: 307 DGRKESLDGFVETFKKELSRDAYPGIYALDCEMCYTTHGLELTRVTVVDA-DMRVVYDTF 365
Query: 355 IKPLGEIIDLNSKFSGIHHIDDTAPTIHEAEKCYICPSMINQNSILIGHGLDNDLRVMRI 414
+KP EI+D N++FSG+ D +I + I S + +ILIGH L++DL +++
Sbjct: 366 VKPDNEIVDYNTRFSGVTEADVAKTSITLPQVQAILLSFFSAQTILIGHSLESDLLALKL 425
Query: 415 VHDKVIDTAVLYP---AGKYKSSLKNLSFEILSRRIQGGE--HDSSEDAIAAMDVIKKKL 469
+H V+DTAVL+P YK SL+NL+ + L++ IQ + H+SSEDA A + ++ K+
Sbjct: 426 IHSTVVDTAVLFPHYLGFPYKRSLRNLAADYLAQIIQNSQDGHNSSEDANACLQLVMWKV 485
>Hs14764743 [L] KOG2248 3'-5' exonuclease
Length = 1221
Score = 139 bits (350), Expect = 9e-33
Identities = 96/307 (31%), Positives = 155/307 (50%), Gaps = 29/307 (9%)
Query: 180 KPKNNSSSLIQRSHVLQKLRSLLLDEETLSRNGFFVK---------MYDTDPINESESDY 230
+P + ++ + + +LR LL ++ L NG+ ++ + +S
Sbjct: 911 RPSSPRVEDLKGAALYSRLREYLLTQDQLKENGYPFPHPERPGGAIIFTAEEKRPKDSSC 970
Query: 231 VECYRCETKFDVT---KIMEPTVCRYHLQRKVYNRETK--KREFPCCGASLESYSDISAG 285
C RC T++ V+ + + C YH R NR + ++ CC A+ S G
Sbjct: 971 RTCCRCGTEYLVSSSGRCIRDEECYYHWGRLRRNRVAGGWETQYMCCSAAAGS-----VG 1025
Query: 286 CMKAKNHVYKWENFTKLSSVVPFKSLVDIKGEENVLALDCEMAFTSKGYEMIRITIVDFW 345
C AK HV V F+ + + ALDCEM++T+ G E+ R+T+VD
Sbjct: 1026 CQVAKQHVQDGRKERLEGFVKTFEKELSGDTHPGIYALDCEMSYTTYGLELTRVTVVDT- 1084
Query: 346 SSEVVYDKVIKPLGEIIDLNSKFSGIHHID--DTAPTIHEAEKCYICPSMINQNSILIGH 403
VVYD +KP EI+D N++FSG+ D DT+ T+ + + + SM + ++ILIGH
Sbjct: 1085 DVHVVYDTFVKPDNEIVDYNTRFSGVTEADLADTSVTLRDVQAVLL--SMFSADTILIGH 1142
Query: 404 GLDNDLRVMRIVHDKVIDTAVLYP---AGKYKSSLKNLSFEILSRRIQGG--EHDSSEDA 458
L++DL ++++H V+DT+VL+P YK SL+NL + L + IQ H SSEDA
Sbjct: 1143 SLESDLLALKVIHSTVVDTSVLFPHRLGLPYKRSLRNLMADYLRQIIQDNVDGHSSSEDA 1202
Query: 459 IAAMDVI 465
A M ++
Sbjct: 1203 GACMHLV 1209
>Hs22050790 [L] KOG2248 3'-5' exonuclease
Length = 539
Score = 135 bits (341), Expect = 1e-31
Identities = 86/247 (34%), Positives = 134/247 (53%), Gaps = 16/247 (6%)
Query: 233 CYRCETKFDVT---KIMEPTVCRYHLQRKVYNRETKKR--EFPCCGASLESYSDISAGCM 287
C RC T++ V+ + + +C YH R ++ R ++ CC A+ S GC
Sbjct: 278 CCRCGTEYLVSSSGRCVRDQLCYYHWGRVRSSQVAGGRVSQYTCCAAAPGS-----VGCQ 332
Query: 288 KAKNHVYKWENFTKLSSVVPFKSLVDIKGEENVLALDCEMAFTSKGYEMIRITIVDFWSS 347
AK HV + V FK + + ALDCEM +T+ G E+ R+T+VD
Sbjct: 333 VAKQHVRDGRKESLDGFVETFKKELSRDAYPGIYALDCEMCYTTHGLELTRVTVVDA-DM 391
Query: 348 EVVYDKVIKPLGEIIDLNSKFSGIHHIDDTAPTIHEAEKCYICPSMINQNSILIGHGLDN 407
VVYD +KP EI+D N++FSG+ D +I + I S + +ILIGH L++
Sbjct: 392 RVVYDTFVKPDNEIVDYNTRFSGVTEADVAKTSITLPQVQAILLSFFSAQTILIGHSLES 451
Query: 408 DLRVMRIVHDKVIDTAVLYP---AGKYKSSLKNLSFEILSRRIQGGE--HDSSEDAIAAM 462
DL ++++H+ V+DTAVL+P YK SL+NL+ + L++ IQ + H+SSEDA A +
Sbjct: 452 DLLALKLIHNTVVDTAVLFPHYLGFPYKRSLRNLAADYLAQIIQDSQDGHNSSEDANACL 511
Query: 463 DVIKKKL 469
++ K+
Sbjct: 512 QLVMWKV 518
>Hs22050759 [L] KOG2248 3'-5' exonuclease
Length = 226
Score = 116 bits (291), Expect = 6e-26
Identities = 63/157 (40%), Positives = 98/157 (62%), Gaps = 6/157 (3%)
Query: 318 ENVLALDCEMAFTSKGYEMIRITIVDFWSSEVVYDKVIKPLGEIIDLNSKFSGIHHIDDT 377
+ + ALDCEM +T+ G E+ R+T+VD VVYD +KP EI+D N++FSG+ D
Sbjct: 50 QEIYALDCEMCYTTHGLELTRVTVVDA-DMRVVYDTFVKPDNEIVDYNTRFSGVTEADVA 108
Query: 378 APTIHEAEKCYICPSMINQNSILIGHGLDNDLRVMRIVHDKVIDTAVLYP---AGKYKSS 434
+I + I S + +ILIGH L++DL ++++H V+DTAVL+P YK S
Sbjct: 109 KTSITLPQVQAILLSFFSAQTILIGHSLESDLLALKLIHSTVVDTAVLFPHYLGFPYKRS 168
Query: 435 LKNLSFEILSRRIQGGE--HDSSEDAIAAMDVIKKKL 469
L+NL+ + L++ IQ + H+SSEDA A + ++ K+
Sbjct: 169 LRNLAADYLAQIIQDSQDGHNSSEDASACLQLVMWKV 205
>7290209 [L] KOG2248 3'-5' exonuclease
Length = 631
Score = 114 bits (286), Expect = 2e-25
Identities = 85/271 (31%), Positives = 146/271 (53%), Gaps = 39/271 (14%)
Query: 233 CYRCETKFDVTKI----MEPTVCRYHLQR-KVYNRETKKREFPCCGASLESYSDISAGCM 287
C RC+ F V ++ + C+YH + + Y + CC ES S GC
Sbjct: 373 CARCKRHFLVDELTGQYLTHEECQYHSGKYQRYYDGVSHGRWTCCNEGEES----SPGCC 428
Query: 288 KAKNHVYKWENFTKLSSVV----PFKSLVDIK----GEEN--VLALDCEMAFTSKGYEMI 337
HV+ SVV P+ V + GE+ V ALDCEM++T +G ++
Sbjct: 429 LGDRHVWS-------GSVVGVNGPYYDFVRTEHRGSGEDEPAVYALDCEMSYTGRGLDVT 481
Query: 338 RITIVDFWSSEVVYDKVIKPLGEIIDLNSKFSGIHHID--DTAPTIHEAEKCYICPSMIN 395
++++V + ++VY+ ++P+ +IID N+++SGI D A ++ E ++ + +I
Sbjct: 482 KVSLVAL-NGQLVYEHFVRPVCDIIDYNTQYSGITETDLCSGAKSLAEVQRDLL--QLIT 538
Query: 396 QNSILIGHGLDNDLRVMRIVHDKVIDTAVLYP---AGKYKSSLKNLSFEILSRRIQGGE- 451
++ILIGHGL+NDLR +R+VH+ +IDT++ +P Y+ +L++L+ L R IQ G+
Sbjct: 539 ADTILIGHGLENDLRALRLVHNTLIDTSISFPHCNGFPYRRALRHLTKVHLKRDIQAGDG 598
Query: 452 ---HDSSEDAIAAMDVIKKKLSIPLDKK-SW 478
H S ED+ A M+++ +++ LD SW
Sbjct: 599 TTGHSSFEDSRACMELMLWRVNRELDPAWSW 629
>YGR276c [L] KOG2248 3'-5' exonuclease
Length = 553
Score = 114 bits (285), Expect = 3e-25
Identities = 64/160 (40%), Positives = 102/160 (63%), Gaps = 9/160 (5%)
Query: 316 GEENVLALDCEMAFTSKGYEMIRITIVDFWSSEVVYDKVIKPLGEIIDLNSKFSGIHHID 375
G ++ ALDCEM + +G + RI++V+F +EV+Y++++KP I+D +++SGI
Sbjct: 221 GGSHIFALDCEMCLSEQGLVLTRISLVNF-DNEVIYEELVKPDVPIVDYLTRYSGITEEK 279
Query: 376 DTA---PTIHEAEKCYICPSMINQNSILIGHGLDNDLRVMRIVHDKVIDTAVLY---PAG 429
T T+ E +K + +I+++ ILIGH L NDL+VM++ H V+DTA++Y
Sbjct: 280 LTVGAKKTLREVQKDLL--KIISRSDILIGHSLQNDLKVMKLKHPLVVDTAIIYHHKAGD 337
Query: 430 KYKSSLKNLSFEILSRRIQGGEHDSSEDAIAAMDVIKKKL 469
+K SLK LS L++ IQ GEHDS EDA A +++ K K+
Sbjct: 338 PFKPSLKYLSETFLNKSIQNGEHDSVEDARACLELTKLKI 377
>7301627 [L] KOG2248 3'-5' exonuclease
Length = 1010
Score = 114 bits (285), Expect = 3e-25
Identities = 84/268 (31%), Positives = 133/268 (49%), Gaps = 46/268 (17%)
Query: 233 CYRCETKF--DVTKIMEPTVCRYHLQRKVYNRETKKREFPCCGASLESYSDISAGCMKAK 290
C RC F D+ + +C YH + Y R + CC + GC A
Sbjct: 747 CSRCGKVFSLDIYEHQSFDMCNYHPKSTGYRRGFTDHQHRCCQQPAGT-----PGCTYAN 801
Query: 291 NHVYKWENFTKLSSVVPFKSLVDIKGEE------NVLALDCEMAFTSKGYEMIRITIVDF 344
HV + + KL+ V K++ +GEE ++ ALDCEM +T+ G E+ R+T+VD
Sbjct: 802 YHVSDYYDPEKLTCFV--KTIE--RGEEFVPTKKDIYALDCEMCYTTHGIELTRVTVVDI 857
Query: 345 WSSEVVYDKVIKPLGEIIDLNS-------------------KFSGIHH--IDDTAPTIHE 383
+ VYD ++KP +I+D N+ +SGI + + TI +
Sbjct: 858 -NGRSVYDALVKPDNQIVDYNTTWVNVAFRLFRINLQYSDFSYSGITEAMLSNETRTIRD 916
Query: 384 AEKCYICPSMINQNSILIGHGLDNDLRVMRIVHDKVIDTAVLYP---AGKYKSSLKNLSF 440
+ + SM + ++L+GH L++DL+ ++++HD V+DT+VL+P K +LK L
Sbjct: 917 VQA--VLMSMFHAKTVLVGHSLESDLKALKLIHDVVVDTSVLFPHKMGPPKKRALKTLCI 974
Query: 441 EILSRRIQGGE--HDSSEDAIAAMDVIK 466
E L R IQ E HDS+EDA + +IK
Sbjct: 975 ENLKRIIQESEAGHDSAEDAEVCIQLIK 1002
>CE25823 [L] KOG2248 3'-5' exonuclease
Length = 305
Score = 113 bits (283), Expect = 5e-25
Identities = 84/258 (32%), Positives = 129/258 (49%), Gaps = 20/258 (7%)
Query: 230 YVECYRCETKFDVTK--IMEPTVCRYHLQRKVYNRETKKREFPCCGASLESYSDISAGCM 287
Y +C RC F + C YH + K ++ T K+ PCC A + GC+
Sbjct: 54 YRKCSRCSKGFYLNPDGTANAQKCVYHHRAK-WDPLTGKKHLPCCSAKP---GPSTKGCL 109
Query: 288 KAKNHVYK--WENFTKLSSVVPFKSLVDIKGEENVLALDCEMAFTSKGYEMIRITIVDFW 345
HV+ WE+ V P D V ALDCE+ T G E+ R+++VD
Sbjct: 110 VEDRHVFSQSWEDTLWEFVVSPQAKGKDDHRSNKVFALDCELVHTLNGLEVARVSLVDM- 168
Query: 346 SSEVVYDKVIKPLGEIIDLNSKFSGIHHIDDTAPTIHEAEKCYICPSMINQNSILIGHGL 405
+V+ D P+ E+I NS FSG+ D + EA + + +IN ++L+GH L
Sbjct: 169 KGKVLLDTFALPVFEVISFNSTFSGVTEKDMESAISLEACRLQLF-QLINSETLLVGHSL 227
Query: 406 DNDLRVMRIVHDKVIDTAVLY----PAGKY--KSSLKNLSFEILSRRIQ--GGEHDSSED 457
++DL+ +R+VH VIDTAVL+ P+ Y K SL+NL+ + L + +Q H S ED
Sbjct: 228 ESDLKALRLVHHNVIDTAVLFSIVDPSRSYILKLSLQNLAKKYLCKDVQSEASGHSSIED 287
Query: 458 AIAAMDVIKKK--LSIPL 473
+ M+++ + LS+ L
Sbjct: 288 SHTCMELLATRHLLSVKL 305
>CE24469 [L] KOG2248 3'-5' exonuclease
Length = 365
Score = 113 bits (282), Expect = 7e-25
Identities = 81/248 (32%), Positives = 124/248 (49%), Gaps = 18/248 (7%)
Query: 230 YVECYRCETKFDVTK--IMEPTVCRYHLQRKVYNRETKKREFPCCGASLESYSDISAGCM 287
Y +C RC F + C YH + K ++ T K+ PCC A + GC+
Sbjct: 91 YRKCSRCSKGFYLNPDGTANAQKCVYHHRAK-WDPLTGKKHLPCCSAKP---GPSTKGCL 146
Query: 288 KAKNHVYK--WENFTKLSSVVPFKSLVDIKGEENVLALDCEMAFTSKGYEMIRITIVDFW 345
HV+ WE+ V P D V ALDCE+ T G E+ R+++VD
Sbjct: 147 VEDRHVFSQSWEDTLWEFVVSPQAKGKDDHRSNKVFALDCELVHTLNGLEVARVSLVDM- 205
Query: 346 SSEVVYDKVIKPLGEIIDLNSKFSGIHHIDDTAPTIHEAEKCYICPSMINQNSILIGHGL 405
+V+ D P+ E+I NS FSG+ D + EA + + +IN ++L+GH L
Sbjct: 206 KGKVLLDTFALPVFEVISFNSTFSGVTEKDMESAISLEACRLQLF-QLINSETLLVGHSL 264
Query: 406 DNDLRVMRIVHDKVIDTAVLY----PAGKY--KSSLKNLSFEILSRRIQ--GGEHDSSED 457
++DL+ +R+VH VIDTAVL+ P+ Y K SL+NL+ + L + +Q H S ED
Sbjct: 265 ESDLKALRLVHHNVIDTAVLFSIVDPSRSYILKLSLQNLAKKYLCKDVQSEASGHSSIED 324
Query: 458 AIAAMDVI 465
+ M+++
Sbjct: 325 SHTCMELL 332
>Hs22047614 [L] KOG2248 3'-5' exonuclease
Length = 646
Score = 112 bits (279), Expect = 2e-24
Identities = 86/301 (28%), Positives = 139/301 (45%), Gaps = 44/301 (14%)
Query: 189 IQRSHVLQKLRSLLLDEETLSRNGF---------FVKMYDTDPINESESDYVECYRCETK 239
+ R+ + +L+ LL ++ L NG+ ++ +S C RC T+
Sbjct: 267 LSRAALYSRLQEFLLTQDQLKENGYPFPHPERPGGAVLFTGQGKGPGDSSCRVCCRCGTE 326
Query: 240 FDVT---KIMEPTVCRYHLQRKVYNRETKKR--EFPCCGASLESYSDISAGCMKAKNHVY 294
+ V+ + + +C YH R ++ R ++ CC A+ S GC AK HV
Sbjct: 327 YLVSSSGRCVRDQLCYYHWGRVRSSQVAGGRVSQYTCCAAAPGS-----VGCQVAKQHVR 381
Query: 295 KWENFTKLSSVVPFKSLVDIKGEENVLALDCEMAFTSKGYEMIRITIVDFWSSEVVYDKV 354
+ V FK + + ALDCEM +T+ G E+ R+T+VD VVYD
Sbjct: 382 DGRKESLHGFVETFKKELSRDAYPGIYALDCEMCYTTHGLELTRVTVVDA-DMRVVYDTF 440
Query: 355 IKPLGEIIDLNSKFSGIHHIDDTAPTIHEAEKCYICPSMINQNSILIGHGLDNDLRVMRI 414
+KP EI+D F +P + CP+ L++DL +++
Sbjct: 441 VKPDNEIVDTTPGF-------PESPRPTSPRRASRCPN------------LESDLLALKL 481
Query: 415 VHDKVIDTAVLYP---AGKYKSSLKNLSFEILSRRIQGGE--HDSSEDAIAAMDVIKKKL 469
+H V+DTAVL+P YK SL+NL+ + L++ IQ + H+SSEDA A + ++ K
Sbjct: 482 IHSTVVDTAVLFPHYLGFPYKRSLRNLAADYLAQIIQDSQDGHNSSEDANACLQLVMWKA 541
Query: 470 S 470
S
Sbjct: 542 S 542
>SPAC637.09 [L] KOG2248 3'-5' exonuclease
Length = 623
Score = 97.8 bits (242), Expect = 3e-20
Identities = 58/156 (37%), Positives = 91/156 (58%), Gaps = 7/156 (4%)
Query: 320 VLALDCEMAFTSKGYEMIRITIVDFWSSEVVYDKVIKPLGEIIDLNSKFSGIHHIDDTAP 379
+LA+DCEM T G E+ R+TIVD SEV+YD+ +KP + D +++SGI
Sbjct: 268 ILAIDCEMVRTENGLEIARVTIVDM-KSEVIYDEFVKPESPVTDYVTQYSGITEEKLRNV 326
Query: 380 TIHEAEKCYICPSMINQNSILIGHGLDNDLRVMRIVHDKVIDTAVLYPAGK---YKSSLK 436
T ++ ++ N++L+GH L++DL ++ H +IDTA +Y + K SLK
Sbjct: 327 TTVLSDVQSYLKKTVDNNTVLLGHSLNSDLNCLKFTHPHIIDTANIYNHTRGPPSKPSLK 386
Query: 437 NLSFEILSRRIQGG---EHDSSEDAIAAMDVIKKKL 469
L+ + L R IQ HDS+EDA+A +D++K K+
Sbjct: 387 WLATKWLRREIQKAGALGHDSAEDALACVDLLKLKV 422
>ECU07g0380 [L] KOG2248 3'-5' exonuclease
Length = 370
Score = 95.5 bits (236), Expect = 2e-19
Identities = 58/158 (36%), Positives = 93/158 (58%), Gaps = 7/158 (4%)
Query: 319 NVLALDCEMAFTSKGYEMIRITIVDFWSSEVVYDKVIKPLGEIIDLNSKFSGI-HHIDDT 377
+++ALD E T G E R+T+VD + EV+YDK+IKP ++D +K+SG+ + D
Sbjct: 146 DIVALDVEKVRTKMGKEPGRVTMVDC-NGEVIYDKIIKPKEPVVDYLTKYSGLTKEVVDR 204
Query: 378 APTIHEAEKCYICPSMINQNSILIGHGLDNDLRVMRIVHDKVIDTAVLY--PAGKYKSSL 435
I + + I N+++IGHG++NDL +R+ HDK+IDTA L+ P G+ K SL
Sbjct: 205 GIDIEIVRNEVL--NFIGTNTVIIGHGIENDLSSLRLYHDKIIDTAHLFLSPLGR-KISL 261
Query: 436 KNLSFEILSRRIQGGEHDSSEDAIAAMDVIKKKLSIPL 473
L+ L++ I HDS DA+ ++++ K+ L
Sbjct: 262 AQLARTYLAKDIHVETHDSRVDAVTCLELLSVKIQYML 299
>At3g15080 [L] KOG2249 3'-5' exonuclease
Length = 273
Score = 85.5 bits (210), Expect = 2e-16
Identities = 56/167 (33%), Positives = 92/167 (54%), Gaps = 21/167 (12%)
Query: 321 LALDCEMAFTSKGYEMI--RITIVDFWSSEVVYDKVIKPLGEIIDLNSKFSGIHHIDDTA 378
+A+DCEM S+G + R+T+V+ W + V+YD+ ++P+ ++D + SGI D
Sbjct: 82 VAMDCEMVGVSQGTKSALGRVTLVNKWGN-VLYDEFVRPVEHVVDFRTSISGIRPRD--- 137
Query: 379 PTIHEAEKCYICPSMINQ---NSILIGHGLDNDLRVMRIVHDK--VIDTAVLYP--AGKY 431
+ +A+ + + + + IL+GH L NDL+ + + H K + DT P GK
Sbjct: 138 --LRKAKDFRVAQTKVAELIKGKILVGHALHNDLKALLLTHPKKDIRDTGEYQPFLKGKT 195
Query: 432 KSSLKNLSFEILSRRIQGGEHDSSEDAIAAMDVIKKKLSIPLDKKSW 478
+ SLK+L+ EIL IQ GEH +DA AAM + +K ++K W
Sbjct: 196 RKSLKHLASEILGADIQNGEHCPIDDARAAMMLYQK------NRKEW 236
>Hs13569913 [L] KOG2248 3'-5' exonuclease
Length = 774
Score = 78.2 bits (191), Expect = 3e-14
Identities = 51/151 (33%), Positives = 86/151 (56%), Gaps = 5/151 (3%)
Query: 320 VLALDCEMAFTSKGYEMIRITIVDFWSSEVVYDKVIKPLGEIIDLNSKFSGIHHIDDTAP 379
+ LDCEM TSKG E+ RI++V V D+++KP +I+D + FSGI
Sbjct: 228 LFGLDCEMCLTSKGRELTRISLVAEGGC-CVMDELVKPENKILDYLTSFSGITKKILNPV 286
Query: 380 TIHEAEKCYICPSMINQNSILIGHGLDNDLRVMRIVHDKVIDTAVLYPAGK-YKSSLKNL 438
T + +++ +++L+GH LD DLR ++++H VIDT++LY + + LK L
Sbjct: 287 TTKLKDVQRQLKALLPPDAVLVGHSLDLDLRALKMIHPYVIDTSLLYVREQGRRFKLKFL 346
Query: 439 SFEILSRRIQGGE---HDSSEDAIAAMDVIK 466
+ IL + IQ + HD++EDA +++ +
Sbjct: 347 AKVILGKDIQCPDRLGHDATEDARTILELAR 377
>At3g50100 [L] KOG2248 3'-5' exonuclease
Length = 406
Score = 75.9 bits (185), Expect = 1e-13
Identities = 51/151 (33%), Positives = 82/151 (53%), Gaps = 8/151 (5%)
Query: 319 NVLALDCEMAFTSKGYE-MIRITIVDFWSSEVVYDKVIKPLGEIIDLNSKFSGIHHIDDT 377
N++A+DCEM G E ++R+ +VD +V+ D+ +KP ++D + +GI D
Sbjct: 139 NMVAVDCEMVLCEDGTEGLVRVGVVDR-DLKVILDEFVKPNKPVVDYRTDITGITAEDIE 197
Query: 378 APTIHEAEKCYICPSMINQNSILIGHGLDNDLRVMRIVHDKVIDTAVL--YPAGK--YKS 433
++ + ++ +IL+GH L+ DL V++I H KVIDTA++ YP + +
Sbjct: 198 NASLSVVDIQETLQPFLSTGTILVGHSLNRDLEVLKIDHPKVIDTALVFKYPNTRKLRRP 257
Query: 434 SLKNLSFEILSRRIQ--GGEHDSSEDAIAAM 462
SL NL IL ++ G HD DA AAM
Sbjct: 258 SLNNLCKSILGYEVRKTGVPHDCVHDASAAM 288
>CE07923 [L] KOG2248 3'-5' exonuclease
Length = 594
Score = 72.4 bits (176), Expect = 1e-12
Identities = 56/174 (32%), Positives = 95/174 (54%), Gaps = 12/174 (6%)
Query: 305 VVPFKS-LVDIKGEENVLALDCEMAFTS-KGYEMIRITIVDFWSSEVVYDKVIKPLGEII 362
VVP K I + ++DCEM T E+ RI+IVD + + ++ D ++KP G I
Sbjct: 205 VVPTKQGYKKISASSPMFSVDCEMCETDVANRELTRISIVDEFENTIL-DTLVKPEGRIT 263
Query: 363 DLNSKFSGI--HHIDDTAPTIHEAEKCYICPSMINQNSILIGHGLDNDLRVMRIVHDKVI 420
D +++SGI ++ T+ + +K S++ ++IL+GH L++DL+ M++ H +
Sbjct: 264 DYVTRWSGITPDMMEGVTTTLGDVQKAI--QSLLPPDAILVGHSLEHDLQAMKMTHPFCL 321
Query: 421 DTAVLY----PAGKYKSSLKNLSFEILSRRIQGG-EHDSSEDAIAAMDVIKKKL 469
D + ++++SLKNL+ L +IQ H S EDA AAM + + KL
Sbjct: 322 DVGHVLNYTNSNTEFRNSLKNLTELFLGAQIQSEFGHCSYEDAWAAMRLAQLKL 375
>7295335 [L] KOG2248 3'-5' exonuclease
Length = 681
Score = 72.4 bits (176), Expect = 1e-12
Identities = 54/164 (32%), Positives = 90/164 (53%), Gaps = 21/164 (12%)
Query: 320 VLALDCEMAFTSKGY-EMIRITIVDFWSSEVVYDKVIKPLGEIIDLNSKFSGIHHIDDTA 378
+ +DCEM T G E+ RI+IV+ + E VY+ ++ P I D +++SGI TA
Sbjct: 356 MFGVDCEMCHTEAGCNELTRISIVNE-NYETVYETLVLPNNRITDYLTQYSGI-----TA 409
Query: 379 PTIHEAEKCYIC-----PSMINQNSILIGHGLDNDLRVMRIVHDKVIDTAVLYPAG---K 430
+ + K ++ ++IL+G L++DL M+++H VIDT+V + +
Sbjct: 410 EIMEQVTKRLDVVQKEVSELLPPDAILVGQSLNSDLNAMKMMHPYVIDTSVCFNTSGVRR 469
Query: 431 YKSSLKNLS----FEILSRRIQGGEHDSSEDAIAAMDVIKKKLS 470
K+ LK+L+ EI+ I G HDS ED+ A + ++KKKL+
Sbjct: 470 RKTKLKDLAKTFLQEIIQENIDG--HDSIEDSRATLKLVKKKLA 511
>7294419 [L] KOG2249 3'-5' exonuclease
Length = 290
Score = 72.0 bits (175), Expect = 2e-12
Identities = 58/163 (35%), Positives = 82/163 (49%), Gaps = 23/163 (14%)
Query: 320 VLALDCEMA---FTSKGYEMIRITIVDFWSSEVVYDKVIKPLGEIIDLNSKFSGIHHID- 375
+LA+DCEM ++ + R++IV+ V+ DK +KP E+ D + SGI D
Sbjct: 117 ILAMDCEMVGVGHNTRDDMLARVSIVNRMG-HVLLDKYVKPRKEVTDYRTSVSGIRPQDI 175
Query: 376 ----DTAPTIHEAEKCYICPSMINQNSILIGHGLDNDLRVMRIVHD--KVIDTAVLYPAG 429
D A +E K + IL+GHGL NDL V+ I H + DT+ P
Sbjct: 176 ANGEDFAAVQNEVMK-------LIHGRILVGHGLRNDLAVLGIRHPFHDIRDTSHYKPLC 228
Query: 430 KYKS-----SLKNLSFEILSRRIQGGEHDSSEDAIAAMDVIKK 467
K S SLK L+ +L + IQ GEH+S EDA AAM + +
Sbjct: 229 KLISNTHTPSLKRLTKAVLGQEIQTGEHNSVEDARAAMGIYNR 271
>SPBC1604.09c [L] KOG2249 3'-5' exonuclease
Length = 260
Score = 70.5 bits (171), Expect = 5e-12
Identities = 52/156 (33%), Positives = 84/156 (53%), Gaps = 14/156 (8%)
Query: 321 LALDCEMAFTSKGYEMI-RITIVDFWSSEVVYDKVIKPLGEIIDLNSKFSGIH--HIDDT 377
+A+DCEM + ++ R++IV++ VVYD ++P ++ D + SG+ H+ D
Sbjct: 94 IAMDCEMVGVADDMSVLARVSIVNY-HGHVVYDTYVRPKEKVTDWRTWVSGVKSFHMRD- 151
Query: 378 APTIHEAEKCYICPSMINQNSILIGHGLDNDLRVMRIVHDK--VIDTAVLYPAGKYKSS- 434
AP+ EK + I N +L+GH + NDL+V+ + H + + DT+ K
Sbjct: 152 APSF---EKVQAEVAKILDNRVLVGHAVHNDLKVLLLSHPRRMIRDTSRFSGYRKLAKGR 208
Query: 435 ---LKNLSFEILSRRIQGGEHDSSEDAIAAMDVIKK 467
LK L+ IL R IQ G+H S +DA A M++ KK
Sbjct: 209 TPGLKKLAEVILGRDIQSGQHSSVQDAQATMELYKK 244
>YOL080c [L] KOG2249 3'-5' exonuclease
Length = 289
Score = 69.7 bits (169), Expect = 9e-12
Identities = 58/161 (36%), Positives = 87/161 (54%), Gaps = 19/161 (11%)
Query: 321 LALDCEMAFTS---KGYEMIRITIVDFWSSEVVYDKVIKPLGEIIDLNSKFSGI--HHID 375
+A+DCE K + RI+IV+++ VV D+ +KP ++++ + SGI H+
Sbjct: 122 IAMDCEFVGVGPEGKESALARISIVNYFG-HVVLDEFVKPREKVVEWRTWVSGIKPEHMK 180
Query: 376 DTAPTIHEAEKCYICPSMINQNSILIGHGLDNDLRVMRIVHDKVI--DTA------VLYP 427
+ A T EA+K + I + IL+GH L +DL + + H K + DT+ LY
Sbjct: 181 N-AITFKEAQKK---TADILEGRILVGHALKHDLEALMLSHPKSLLRDTSRHLPFRKLYA 236
Query: 428 AGKYKSSLKNLSFEILSRRIQGGEHDSSEDAIAAMDVIKKK 468
GK SLK L+ E+L IQ GEH S EDA A M + KK+
Sbjct: 237 KGK-TPSLKKLTREVLKISIQEGEHSSVEDARATMLLYKKE 276
>At5g25800 [L] KOG2248 3'-5' exonuclease
Length = 534
Score = 68.2 bits (165), Expect = 3e-11
Identities = 47/152 (30%), Positives = 79/152 (51%), Gaps = 37/152 (24%)
Query: 320 VLALDCEMAFTSKGYEMIRITIVDFWSSEVVYDKVIKPLGEIIDLNSKFSGIHHI--DDT 377
++ALDCEM +G E+ R+T+VD +V+ DK++ P I D N+++SGI + +
Sbjct: 215 IVALDCEM----EGLELTRVTLVDI-QGQVLLDKLVMPTNPITDYNTRYSGITAVMMEGV 269
Query: 378 APTIHEAEKCYICPSMINQNSILIGHGLDNDLRVMRIVHDKVIDTAVLYPAGKYKSSLKN 437
T+ + ++ ++ ++ + +IL+GH L+NDL ++I H N
Sbjct: 270 TTTLKDIQEEFL--KLVFKETILVGHSLENDLLSLKISH--------------------N 307
Query: 438 LSFEILSRRIQGGEHDSSEDAIAAMDVIKKKL 469
L E HDS+EDA AAMD+ K+
Sbjct: 308 LESE--------SGHDSAEDAKAAMDLALLKI 331
>At5g05540 [L] KOG2248 3'-5' exonuclease
Length = 466
Score = 67.0 bits (162), Expect = 6e-11
Identities = 51/175 (29%), Positives = 90/175 (51%), Gaps = 19/175 (10%)
Query: 320 VLALDCEMAFTSKGYE-MIRITIVDFWSSEVVYDKVIKPLGEIIDLNSKFSGIHHIDDTA 378
++A+DCEM G E ++R+ VD +V+ D+ +KP ++D + +G+ D
Sbjct: 142 MIAIDCEMVLCEDGSEAVVRVAAVDR-DLKVILDEFVKPNQPVVDYRTFITGLTAQDLEK 200
Query: 379 PTIHEAEKCYICPSMINQNSILIGHGLDNDLRVMRIVHDKVIDTAVLY---------PAG 429
TI + I++++IL+G L++DL+V+++ H +VIDT++++ P
Sbjct: 201 ATISVVDIQEKLLMFISEDTILVGQSLNHDLKVLKVDHARVIDTSLVFKYNYDGTRRPLR 260
Query: 430 KYKSSLKNLSFEILSRRIQ--GGEHDSSEDAIAAMDVIKKKL------SIPLDKK 476
+ SL L IL +Q G H+ DA AAM ++ L S+PL K+
Sbjct: 261 LKRPSLNYLCKCILGYEVQKEGVPHNCVHDAEAAMKLVLAILDNGAETSVPLSKE 315
>Hs9966857_2 [L] KOG2249 3'-5' exonuclease
Length = 252
Score = 65.5 bits (158), Expect = 2e-10
Identities = 56/159 (35%), Positives = 82/159 (51%), Gaps = 18/159 (11%)
Query: 316 GEENVLALDCEMAFTS-KGYEMI--RITIVDFWSSEVVYDKVIKPLGEIIDLNSKFSGIH 372
G LALDCEM KG E + R++IV+ + + VYDK +KP + D + SGI
Sbjct: 69 GLTRALALDCEMVGVGPKGEESMAARVSIVNQYG-KCVYDKYVKPTEPVTDYRTAVSGIR 127
Query: 373 HIDDTAPTIHEAEKCYICPSMINQ---NSILIGHGLDNDLRVMRIVHDK--VIDTAVLYP 427
+ + E+ + + + IL+GH L NDL+V+ + H K + DT P
Sbjct: 128 -----PENLKQGEELEVVQKEVAEMLKGRILVGHALHNDLKVLFLDHPKKKIRDTQKYKP 182
Query: 428 -AGKYKS---SLKNLSFEILSRRIQGGEHDSSEDAIAAM 462
+ KS SL+ LS +IL ++Q EH S +DA AAM
Sbjct: 183 FKSQVKSGRPSLRLLSEKILGLQVQQAEHCSIQDAQAAM 221
>Hs13569960 [L] KOG2249 3'-5' exonuclease
Length = 353
Score = 65.1 bits (157), Expect = 2e-10
Identities = 52/164 (31%), Positives = 89/164 (53%), Gaps = 23/164 (14%)
Query: 320 VLALDCEMAFTS-KGY--EMIRITIVDFWSSEVVYDKVIKPLGEIIDLNSKFSGI---HH 373
++A+DCEM T KG+ + R +IV++ + +V+YD+ I P I+D +++SGI H
Sbjct: 179 MVAIDCEMVGTGPKGHVSSLARCSIVNY-NGDVLYDEYILPPCHIVDYRTRWSGIRKQHM 237
Query: 374 IDDTAPTIHEAEKCYICPSMINQNSILIGHGLDNDLRVMRIVHDKVI--DTAVLYPAGKY 431
++ T I + I I++GH + ND + ++ H K + DT+ + P +
Sbjct: 238 VNATPFKIARGQILKIL-----TGKIVVGHAIHNDFKALQYFHPKSLTRDTSHIPPLNRK 292
Query: 432 KS-------SLKNLSFEILSRRIQGGE--HDSSEDAIAAMDVIK 466
SLK+L+ ++L+R IQ G+ H S EDA A M++ K
Sbjct: 293 ADCPENATMSLKHLTKKLLNRDIQVGKSGHSSVEDAQATMELYK 336
>Hs21362094 [L] KOG2249 3'-5' exonuclease
Length = 325
Score = 64.7 bits (156), Expect = 3e-10
Identities = 48/162 (29%), Positives = 84/162 (51%), Gaps = 21/162 (12%)
Query: 321 LALDCEMAFTS---KGYEMIRITIVDFWSSEVVYDKVIKPLGEIIDLNSKFSGI--HHID 375
+A+DCEM T + E+ R +IV + +V+YDK I+P I D +++SGI H+
Sbjct: 111 VAIDCEMVGTGPRGRVSELARCSIVSY-HGDVLYDKYIRPEMPIADYRTRWSGITRQHMR 169
Query: 376 DTAPTIHEAEKCYICPSMINQNSILIGHGLDNDLRVMRIVHDKVIDTAVLYPAG------ 429
P A+K + + + +++GH L ND + ++ VH + Y
Sbjct: 170 KAVP-FQVAQKEIL---KLLKGKVVVGHALHNDFQALKYVHPRSQTRDTTYVPNFLSEPG 225
Query: 430 ---KYKSSLKNLSFEILSRRIQGGE--HDSSEDAIAAMDVIK 466
+ + SLK+L+ ++L ++IQ G+ H S EDA AM++ +
Sbjct: 226 LHTRARVSLKDLALQLLHKKIQVGQHGHSSVEDATTAMELYR 267
>CE19046 [L] KOG2249 3'-5' exonuclease
Length = 269
Score = 64.3 bits (155), Expect = 4e-10
Identities = 52/162 (32%), Positives = 83/162 (51%), Gaps = 16/162 (9%)
Query: 320 VLALDCEMAFTSKGYE---MIRITIVDFWSSEVVYDKVIKPLGEIIDLNSKFSGIHHIDD 376
V+A+DCE G + RI+IV+ ++VYDK +KP ++ D + SGI +
Sbjct: 102 VIAIDCEYVGAGMGGTTDILARISIVNELG-KIVYDKFVKPTEKVTDFRTAVSGIRPENM 160
Query: 377 TAPTIHEAEKCYICPSMINQNSILIGHGLDNDLRVMRIVHDKVI--DTA---VLYPAGKY 431
+ + + S + I+IGH + ND RV+++ H + + DTA +L +
Sbjct: 161 IKAIPFDRAQTEV--SKLIDGRIVIGHAVHNDFRVLKLNHIRKLTRDTAKCTILKNMANH 218
Query: 432 KS--SLKNLSFEILSRRIQGGEHDSSEDAIAAM---DVIKKK 468
SLK L+ E+L IQ GEHDS DA A+ + +KK+
Sbjct: 219 HGTPSLKKLAKEVLGIEIQRGEHDSITDARVALRLYEAVKKQ 260
>Hs22057667 [L] KOG2249 3'-5' exonuclease
Length = 325
Score = 63.9 bits (154), Expect = 5e-10
Identities = 48/162 (29%), Positives = 84/162 (51%), Gaps = 21/162 (12%)
Query: 321 LALDCEMAFTS---KGYEMIRITIVDFWSSEVVYDKVIKPLGEIIDLNSKFSGI--HHID 375
+A+DCEM T + E+ R +IV + + V+YDK I+P I D +++SGI H+
Sbjct: 111 VAIDCEMVGTGPRGRVSELARCSIVSYHGN-VLYDKYIRPEMPIADYRTRWSGITRQHMR 169
Query: 376 DTAPTIHEAEKCYICPSMINQNSILIGHGLDNDLRVMRIVHDKVIDTAVLYPAG------ 429
P A+K + + + +++GH L ND + ++ VH + Y
Sbjct: 170 KAVP-FQVAQKEIL---KLLKGKVVVGHALHNDFQALKYVHPRSQTRDTTYVPNFLSEPG 225
Query: 430 ---KYKSSLKNLSFEILSRRIQGGE--HDSSEDAIAAMDVIK 466
+ + SLK+L+ ++L ++IQ G+ H S EDA AM++ +
Sbjct: 226 LHTRARVSLKDLALQLLHKKIQVGQHGHSSVEDATTAMELYR 267
>HsM12232443 [L] KOG2249 3'-5' exonuclease
Length = 209
Score = 58.2 bits (139), Expect = 3e-08
Identities = 42/145 (28%), Positives = 75/145 (50%), Gaps = 18/145 (12%)
Query: 335 EMIRITIVDFWSSEVVYDKVIKPLGEIIDLNSKFSGI--HHIDDTAPTIHEAEKCYICPS 392
E+ R +IV + +V+YDK I+P I D +++SGI H+ P A+K +
Sbjct: 12 ELARCSIVSY-HGDVLYDKYIRPEMPIADYRTRWSGITRQHMRKAVP-FQVAQKEIL--- 66
Query: 393 MINQNSILIGHGLDNDLRVMRIVHDKVIDTAVLYPAG---------KYKSSLKNLSFEIL 443
+ + +++GH L ND + ++ VH + Y + + SLK+L+ ++L
Sbjct: 67 KLLKGKVVVGHALHNDFQALKYVHPRSQTRDTTYVPNFLSEPGLHTRARVSLKDLALQLL 126
Query: 444 SRRIQGGE--HDSSEDAIAAMDVIK 466
++IQ G+ H S EDA AM++ +
Sbjct: 127 HKKIQVGQHGHSSVEDATTAMELYR 151
>CE01269 [L] KOG1275 PAB-dependent poly(A) ribonuclease subunit PAN2
Length = 1131
Score = 56.6 bits (135), Expect = 8e-08
Identities = 54/185 (29%), Positives = 86/185 (46%), Gaps = 23/185 (12%)
Query: 309 KSLVDIKGEENVLALDCE--------MAFTSKGYEMI---RITIVDFWSSEVVYDKVIKP 357
+SL ++ E+ ++ LD E + F K +M R + VD +++D +K
Sbjct: 897 QSLEELPKEKELVGLDAEFIKIKTDLLEFDGKTVQMRAVGRASCVDSTGERIIFDDHVKL 956
Query: 358 LG--EIIDLNSKFSGIHHIDDTAPTIHEA-----EKCYICPSMINQNSI-LIGHGLDNDL 409
E++D +KFSGI D PT E ++ + ++ Q + +GH L ND
Sbjct: 957 TDDVEVVDYLTKFSGIVKAD-LCPTTSEKYLTTHKRLLLRMHVLIQRGVTFVGHALHNDF 1015
Query: 410 RVMRI--VHDKVIDTAVLYPAGKYKS-SLKNLSFEILSRRIQGGEHDSSEDAIAAMDVIK 466
V+ + ++IDT L G + SL+ L EIL IQ HDS DA A+ + +
Sbjct: 1016 TVLNVHVAESQIIDTVTLMRLGTQRMLSLQFLVKEILGETIQMEAHDSVVDARYALKLYR 1075
Query: 467 KKLSI 471
K L I
Sbjct: 1076 KYLEI 1080
>YGL094c [L] KOG1275 PAB-dependent poly(A) ribonuclease subunit PAN2
Length = 1115
Score = 55.1 bits (131), Expect = 2e-07
Identities = 29/75 (38%), Positives = 46/75 (60%), Gaps = 2/75 (2%)
Query: 399 ILIGHGLDNDLRVMRI--VHDKVIDTAVLYPAGKYKSSLKNLSFEILSRRIQGGEHDSSE 456
+ +GHGL+ND + + I +++ DTA+ + GK SL+ L++ +L IQ G HDS E
Sbjct: 1011 VFVGHGLNNDFKHININVPRNQIRDTAIYFLQGKRYLSLRYLAYVLLGMNIQEGNHDSIE 1070
Query: 457 DAIAAMDVIKKKLSI 471
DA A+ + KK L +
Sbjct: 1071 DAHTALILYKKYLHL 1085
>SPAC22G7.04 [L] KOG1275 PAB-dependent poly(A) ribonuclease subunit PAN2
Length = 1115
Score = 52.8 bits (125), Expect = 1e-06
Identities = 37/112 (33%), Positives = 63/112 (56%), Gaps = 9/112 (8%)
Query: 360 EIIDLNSKFSGIHHID---DTAP-TIHEAEKCYI-CPSMINQNSILIGHGLDNDLRVMRI 414
++ D +++SGIH D D +P + + Y ++N I +GHGL D R++ +
Sbjct: 946 KVTDYLTEYSGIHPGDLDPDRSPYNVVPLKVAYKKLRLLVNAGCIFVGHGLQKDFRIINL 1005
Query: 415 V--HDKVIDTAVLY--PAGKYKSSLKNLSFEILSRRIQGGEHDSSEDAIAAM 462
+ ++V+DT L+ + + K SLK L++ +L IQ EHDS EDA+ A+
Sbjct: 1006 LVPPEQVVDTVDLFFLSSRQRKLSLKFLAWYLLDEEIQLTEHDSIEDALTAL 1057
>Hs6857800 [L] KOG2249 3'-5' exonuclease
Length = 181
Score = 52.0 bits (123), Expect = 2e-06
Identities = 47/166 (28%), Positives = 80/166 (47%), Gaps = 24/166 (14%)
Query: 316 GEENVLALDCEMAFTSKGYE--MIRITIVDFWSSEVVYDKVIKPLGEIIDLNSKFSGI-- 371
G V+A+DCEM E + R ++V+ + V+YDK I+P GEI D ++ SG+
Sbjct: 3 GSREVVAMDCEMVGLGPHRESGLARCSLVNVHGA-VLYDKFIRPEGEITDYRTRVSGVTP 61
Query: 372 -HHIDDTAPTIHEAEKCYICPSMINQNSILIGHGLDNDLRVMR------IVHDKVIDTAV 424
H + T + E + + +++GH L +D + ++ ++D D +
Sbjct: 62 QHMVGATPFAVARLEILQLL-----KGKLVVGHDLKHDFQALKEDMSGYTIYDTSTD-RL 115
Query: 425 LYPAGKY----KSSLKNLSFEILSRRIQGG--EHDSSEDAIAAMDV 464
L+ K + SL+ LS +L + IQ H S EDA A M++
Sbjct: 116 LWREAKLDHCRRVSLRVLSERLLHKSIQNSLLGHSSVEDARATMEL 161
>7303975 [L] KOG1275 PAB-dependent poly(A) ribonuclease subunit PAN2
Length = 1209
Score = 52.0 bits (123), Expect = 2e-06
Identities = 30/87 (34%), Positives = 49/87 (55%), Gaps = 3/87 (3%)
Query: 393 MINQNSILIGHGLDNDLRVMRIV--HDKVIDTAVLYPAGKYKS-SLKNLSFEILSRRIQG 449
+++ I +GHGL ND RV+ I +++IDT L+ ++ SL+ L++ L +IQ
Sbjct: 1101 LVDVGVIFVGHGLKNDFRVINIYVPSEQIIDTVHLFHMPHHRMVSLRFLAWHFLGTKIQS 1160
Query: 450 GEHDSSEDAIAAMDVIKKKLSIPLDKK 476
HDS EDA + + K L + +KK
Sbjct: 1161 ETHDSIEDARTTLQLYKHYLKLQEEKK 1187
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.319 0.134 0.393
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,197,687
Number of Sequences: 60738
Number of extensions: 1200866
Number of successful extensions: 3366
Number of sequences better than 1.0e-05: 35
Number of HSP's better than 0.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 29
Number of HSP's that attempted gapping in prelim test: 3281
Number of HSP's gapped (non-prelim): 39
length of query: 478
length of database: 30,389,216
effective HSP length: 110
effective length of query: 368
effective length of database: 23,708,036
effective search space: 8724557248
effective search space used: 8724557248
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)