ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI5380 check: MH T KOG0660 Signal transduction mechanisms Mitogen-activated protein kinase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI5380 1867209 1868540 444
(444 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YLR113w [T] KOG0660 Mitogen-activated protein kinase 695 0.0
SPAC24B11.06c [T] KOG0660 Mitogen-activated protein kinase 594 e-169
Hs20986512 [T] KOG0660 Mitogen-activated protein kinase 372 e-103
Hs4503069 [T] KOG0660 Mitogen-activated protein kinase 369 e-102
7298087 [T] KOG0660 Mitogen-activated protein kinase 366 e-101
Hs20128774 [T] KOG0660 Mitogen-activated protein kinase 352 5e-97
7301110 [T] KOG0660 Mitogen-activated protein kinase 352 6e-97
At2g43790 [T] KOG0660 Mitogen-activated protein kinase 346 5e-95
At3g45640 [T] KOG0660 Mitogen-activated protein kinase 345 1e-94
Hs20986531 [T] KOG0660 Mitogen-activated protein kinase 343 4e-94
Hs20986529 [T] KOG0660 Mitogen-activated protein kinase 342 5e-94
Hs4506785 [T] KOG0660 Mitogen-activated protein kinase 341 1e-93
At4g01370 [T] KOG0660 Mitogen-activated protein kinase 340 2e-93
CE06686 [T] KOG0660 Mitogen-activated protein kinase 338 7e-93
At1g07880 [T] KOG0660 Mitogen-activated protein kinase 334 1e-91
CE24971 [T] KOG0660 Mitogen-activated protein kinase 331 2e-90
CE01583 [T] KOG0660 Mitogen-activated protein kinase 331 2e-90
At3g59790 [T] KOG0660 Mitogen-activated protein kinase 329 6e-90
At4g11330 [T] KOG0660 Mitogen-activated protein kinase 327 3e-89
SPAC31G5.09c [T] KOG0660 Mitogen-activated protein kinase 324 1e-88
Hs20562757 [T] KOG0660 Mitogen-activated protein kinase 322 9e-88
Hs4506085 [T] KOG0660 Mitogen-activated protein kinase 319 5e-87
At1g59580 [T] KOG0660 Mitogen-activated protein kinase 318 1e-86
At1g10210 [T] KOG0660 Mitogen-activated protein kinase 317 2e-86
At2g46070 [T] KOG0660 Mitogen-activated protein kinase 314 1e-85
Hs20986501 [T] KOG0660 Mitogen-activated protein kinase 314 2e-85
Hs20986497 [T] KOG0660 Mitogen-activated protein kinase 314 2e-85
At2g18170 [T] KOG0660 Mitogen-activated protein kinase 307 2e-83
YHR030c [T] KOG0660 Mitogen-activated protein kinase 305 1e-82
SPBC119.08 [T] KOG0660 Mitogen-activated protein kinase 305 1e-82
At4g36450 [T] KOG0660 Mitogen-activated protein kinase 300 3e-81
YGR040w [T] KOG0660 Mitogen-activated protein kinase 298 8e-81
YBL016w [T] KOG0660 Mitogen-activated protein kinase 297 2e-80
At1g18150 [T] KOG0660 Mitogen-activated protein kinase 297 2e-80
Hs20986514 [T] KOG0660 Mitogen-activated protein kinase 294 2e-79
At3g14720 [T] KOG0660 Mitogen-activated protein kinase 291 1e-78
At2g42880 [T] KOG0660 Mitogen-activated protein kinase 289 5e-78
At1g73670 [T] KOG0660 Mitogen-activated protein kinase 288 1e-77
At1g53510 [T] KOG0660 Mitogen-activated protein kinase 287 2e-77
Hs20986516 [T] KOG0660 Mitogen-activated protein kinase 286 3e-77
At3g18040 [T] KOG0660 Mitogen-activated protein kinase 281 1e-75
At5g19010 [T] KOG0660 Mitogen-activated protein kinase 280 3e-75
CE17062 [T] KOG0660 Mitogen-activated protein kinase 280 4e-75
CE06762 [T] KOG0660 Mitogen-activated protein kinase 271 1e-72
At2g01450 [T] KOG0660 Mitogen-activated protein kinase 268 1e-71
Hs21237745 [T] KOG0665 Jun-N-terminal kinase (JNK) 262 7e-70
Hs21237742 [T] KOG0665 Jun-N-terminal kinase (JNK) 261 1e-69
Hs20986521 [T] KOG0665 Jun-N-terminal kinase (JNK) 260 3e-69
Hs20986519 [T] KOG0665 Jun-N-terminal kinase (JNK) 260 3e-69
Hs4506081 [T] KOG0665 Jun-N-terminal kinase (JNK) 259 4e-69
Hs20986510 [T] KOG0665 Jun-N-terminal kinase (JNK) 259 4e-69
Hs20986506 [T] KOG0665 Jun-N-terminal kinase (JNK) 259 4e-69
7297631 [T] KOG0665 Jun-N-terminal kinase (JNK) 259 4e-69
Hs21237736 [T] KOG0665 Jun-N-terminal kinase (JNK) 258 1e-68
HsM20070143 [T] KOG0665 Jun-N-terminal kinase (JNK) 258 2e-68
CE27574 [T] KOG0665 Jun-N-terminal kinase (JNK) 258 2e-68
Hs21237739 [T] KOG0665 Jun-N-terminal kinase (JNK) 257 2e-68
Hs7706445 [T] KOG0664 Nemo-like MAPK-related serine/threonine pr... 256 6e-68
Hs4506095 [T] KOG0665 Jun-N-terminal kinase (JNK) 255 1e-67
Hs20986523 [T] KOG0665 Jun-N-terminal kinase (JNK) 255 1e-67
YKL161c [T] KOG0660 Mitogen-activated protein kinase 251 2e-66
Hs20986499 [T] KOG0660 Mitogen-activated protein kinase 242 9e-64
7295173 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 241 2e-63
CE29466 [T] KOG0665 Jun-N-terminal kinase (JNK) 238 1e-62
CE02602_1 [T] KOG0660 Mitogen-activated protein kinase 233 4e-61
CE29478 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 231 2e-60
CE29477 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 231 2e-60
CE29476 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 231 2e-60
CE29318 [T] KOG0660 Mitogen-activated protein kinase 229 6e-60
Hs4506091 [T] KOG0660 Mitogen-activated protein kinase 221 2e-57
YPR054w [T] KOG0660 Mitogen-activated protein kinase 220 4e-57
CE17305 [T] KOG0665 Jun-N-terminal kinase (JNK) 219 6e-57
CE29020 [T] KOG0660 Mitogen-activated protein kinase 216 5e-56
CE27220 [T] KOG0660 Mitogen-activated protein kinase 209 7e-54
Hs4506089 [T] KOG0660 Mitogen-activated protein kinase 206 4e-53
At3g48750 [R] KOG0594 Protein kinase PCTAIRE and related kinases 199 5e-51
7291043 [T] KOG0660 Mitogen-activated protein kinase 199 7e-51
Hs4502709 [R] KOG0594 Protein kinase PCTAIRE and related kinases 194 2e-49
7297680 [R] KOG0594 Protein kinase PCTAIRE and related kinases 193 4e-49
Hs4557439 [R] KOG0594 Protein kinase PCTAIRE and related kinases 192 8e-49
At1g73690 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 189 7e-48
YBR160w [R] KOG0594 Protein kinase PCTAIRE and related kinases 182 9e-46
Hs20986508 [T] KOG0665 Jun-N-terminal kinase (JNK) 181 2e-45
At1g66750 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 181 2e-45
Hs16936528 [R] KOG0594 Protein kinase PCTAIRE and related kinases 181 3e-45
CE26422 [D] KOG0600 Cdc2-related protein kinase 181 3e-45
ECU08g1920 [R] KOG0594 Protein kinase PCTAIRE and related kinases 180 3e-45
Hs20502986 [T] KOG0660 Mitogen-activated protein kinase 178 2e-44
At1g57870 [G] KOG0658 Glycogen synthase kinase-3 177 2e-44
At1g18040 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 177 4e-44
7297578 [T] KOG0661 MAPK related serine/threonine protein kinase 177 4e-44
7300773 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 176 5e-44
Hs11496279 [T] KOG0661 MAPK related serine/threonine protein kinase 176 8e-44
Hs7705551 [T] KOG0661 MAPK related serine/threonine protein kinase 175 1e-43
Hs4826675 [UT] KOG0662 Cyclin-dependent kinase CDK5 175 1e-43
At2g38620 [R] KOG0594 Protein kinase PCTAIRE and related kinases 175 1e-43
SPBC11B10.09 [R] KOG0594 Protein kinase PCTAIRE and related kinases 175 1e-43
Hs7662388 [T] KOG0661 MAPK related serine/threonine protein kinase 175 1e-43
SPAC1687.15 [G] KOG0658 Glycogen synthase kinase-3 174 2e-43
At4g18710 [G] KOG0658 Glycogen synthase kinase-3 174 2e-43
Hs4505569 [R] KOG0593 Predicted protein kinase KKIAMRE 174 2e-43
Hs4505649 [R] KOG0594 Protein kinase PCTAIRE and related kinases 173 4e-43
At1g09840 [G] KOG0658 Glycogen synthase kinase-3 172 7e-43
SPBC18H10.15 [R] KOG0663 Protein kinase PITSLRE and related kinases 172 9e-43
At3g05840 [G] KOG0658 Glycogen synthase kinase-3 172 1e-42
Hs5453860 [R] KOG0594 Protein kinase PCTAIRE and related kinases 171 2e-42
Hs15011928 [R] KOG0594 Protein kinase PCTAIRE and related kinases 171 2e-42
At1g06390 [G] KOG0658 Glycogen synthase kinase-3 171 2e-42
Hs4758652 [R] KOG0593 Predicted protein kinase KKIAMRE 171 3e-42
At5g26751 [G] KOG0658 Glycogen synthase kinase-3 171 3e-42
CE29073 [R] KOG0594 Protein kinase PCTAIRE and related kinases 170 3e-42
CE06779 [R] KOG0594 Protein kinase PCTAIRE and related kinases 170 3e-42
At5g50860 [D] KOG0600 Cdc2-related protein kinase 170 4e-42
At2g30980 [G] KOG0658 Glycogen synthase kinase-3 170 4e-42
Hs21040235 [R] KOG0594 Protein kinase PCTAIRE and related kinases 169 6e-42
YPL031c [R] KOG0594 Protein kinase PCTAIRE and related kinases 169 1e-41
SPAC2F3.15 [D] KOG0600 Cdc2-related protein kinase 169 1e-41
At5g10270 [D] KOG0600 Cdc2-related protein kinase 169 1e-41
Hs4502731 [R] KOG0663 Protein kinase PITSLRE and related kinases 168 1e-41
Hs16950647 [R] KOG0663 Protein kinase PITSLRE and related kinases 168 1e-41
YMR139w [G] KOG0658 Glycogen synthase kinase-3 168 2e-41
At5g64960 [D] KOG0600 Cdc2-related protein kinase 168 2e-41
At1g03740 [D] KOG0600 Cdc2-related protein kinase 168 2e-41
Hs4502735 [R] KOG0594 Protein kinase PCTAIRE and related kinases 167 3e-41
At4g13020 [T] KOG0661 MAPK related serine/threonine protein kinase 167 3e-41
7297009 [R] KOG0593 Predicted protein kinase KKIAMRE 167 3e-41
7300650 [R] KOG0594 Protein kinase PCTAIRE and related kinases 167 4e-41
At3g05050 [D] KOG0600 Cdc2-related protein kinase 166 5e-41
7292375 [R] KOG0594 Protein kinase PCTAIRE and related kinases 166 6e-41
At5g45430 [T] KOG0661 MAPK related serine/threonine protein kinase 166 8e-41
Hs4502743 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 165 1e-40
At5g63370 [R] KOG0663 Protein kinase PITSLRE and related kinases 165 1e-40
At3g61160 [G] KOG0658 Glycogen synthase kinase-3 165 1e-40
At5g63610 [K] KOG0666 Cyclin C-dependent kinase CDK8 165 1e-40
At4g00720 [G] KOG0658 Glycogen synthase kinase-3 165 1e-40
At1g54610 [D] KOG0600 Cdc2-related protein kinase 165 1e-40
Hs16160923 [R] KOG0594 Protein kinase PCTAIRE and related kinases 164 2e-40
7303804 [R] KOG0663 Protein kinase PITSLRE and related kinases 164 2e-40
At3g54180 [R] KOG0594 Protein kinase PCTAIRE and related kinases 164 2e-40
7290565 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 164 3e-40
CE20258 [R] KOG0593 Predicted protein kinase KKIAMRE 163 4e-40
At1g33770 [D] KOG0600 Cdc2-related protein kinase 163 4e-40
At5g14640 [G] KOG0658 Glycogen synthase kinase-3 163 5e-40
At1g67580 [R] KOG0663 Protein kinase PITSLRE and related kinases 163 5e-40
SPBC8D2.01 [G] KOG0658 Glycogen synthase kinase-3 162 7e-40
At1g71530 [D] KOG0600 Cdc2-related protein kinase 162 7e-40
At5g44290 [D] KOG0600 Cdc2-related protein kinase 162 9e-40
At4g22940 [D] KOG0600 Cdc2-related protein kinase 162 9e-40
At4g10010 [D] KOG0600 Cdc2-related protein kinase 162 9e-40
Hs7657498 [T] KOG0661 MAPK related serine/threonine protein kinase 162 1e-39
CE12408 [T] KOG0661 MAPK related serine/threonine protein kinase 162 1e-39
HsM4504163 [G] KOG0658 Glycogen synthase kinase-3 161 2e-39
Hs4507281 [R] KOG0593 Predicted protein kinase KKIAMRE 161 2e-39
CE21401 [G] KOG0658 Glycogen synthase kinase-3 161 2e-39
CE00315 [R] KOG0594 Protein kinase PCTAIRE and related kinases 161 2e-39
7290342 [G] KOG0658 Glycogen synthase kinase-3 161 2e-39
SPBC19F8.07 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polyme... 160 3e-39
At4g19110 [T] KOG0661 MAPK related serine/threonine protein kinase 160 3e-39
7303051 [UT] KOG0662 Cyclin-dependent kinase CDK5 160 3e-39
CE21213 [UT] KOG0662 Cyclin-dependent kinase CDK5 160 5e-39
At1g53050 [D] KOG0600 Cdc2-related protein kinase 159 6e-39
Hs16357496 [R] KOG0663 Protein kinase PITSLRE and related kinases 159 8e-39
Hs16332372 [R] KOG0663 Protein kinase PITSLRE and related kinases 159 8e-39
Hs16332370 [R] KOG0663 Protein kinase PITSLRE and related kinases 159 8e-39
Hs16332368 [R] KOG0663 Protein kinase PITSLRE and related kinases 159 8e-39
Hs16332366 [R] KOG0663 Protein kinase PITSLRE and related kinases 159 8e-39
Hs16332364 [R] KOG0663 Protein kinase PITSLRE and related kinases 159 8e-39
Hs16332362 [R] KOG0663 Protein kinase PITSLRE and related kinases 159 8e-39
Hs16332360 [R] KOG0663 Protein kinase PITSLRE and related kinases 159 8e-39
Hs16332358 [R] KOG0663 Protein kinase PITSLRE and related kinases 159 8e-39
Hs10835055 [R] KOG0663 Protein kinase PITSLRE and related kinases 159 8e-39
At1g18670 [D] KOG0600 Cdc2-related protein kinase 159 8e-39
At1g09600 [D] KOG0600 Cdc2-related protein kinase 159 8e-39
Hs22051130 [G] KOG0658 Glycogen synthase kinase-3 159 1e-38
Hs16357498 [R] KOG0663 Protein kinase PITSLRE and related kinases 159 1e-38
Hs16357486 [R] KOG0663 Protein kinase PITSLRE and related kinases 159 1e-38
Hs16357484 [R] KOG0663 Protein kinase PITSLRE and related kinases 159 1e-38
Hs16357482 [R] KOG0663 Protein kinase PITSLRE and related kinases 159 1e-38
Hs16357480 [R] KOG0663 Protein kinase PITSLRE and related kinases 159 1e-38
Hs11995474 [G] KOG0658 Glycogen synthase kinase-3 159 1e-38
At1g76540 [R] KOG0594 Protein kinase PCTAIRE and related kinases 159 1e-38
At1g57700 [D] KOG0600 Cdc2-related protein kinase 159 1e-38
At5g39420 [D] KOG0600 Cdc2-related protein kinase 158 1e-38
Hs16357494 [R] KOG0663 Protein kinase PITSLRE and related kinases 158 2e-38
Hs16357492 [R] KOG0663 Protein kinase PITSLRE and related kinases 158 2e-38
At1g74330 [D] KOG0600 Cdc2-related protein kinase 158 2e-38
At1g20930 [R] KOG0594 Protein kinase PCTAIRE and related kinases 158 2e-38
Hs6912584 [R] KOG0594 Protein kinase PCTAIRE and related kinases 157 3e-38
CE23605 [T] KOG0665 Jun-N-terminal kinase (JNK) 157 3e-38
CE11556 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 157 4e-38
Hs4502741 [R] KOG0594 Protein kinase PCTAIRE and related kinases 156 7e-38
ECU11g1290 [R] KOG0663 Protein kinase PITSLRE and related kinases 155 9e-38
Hs21361340 [G] KOG0658 Glycogen synthase kinase-3 155 1e-37
SPCC16C4.11 [R] KOG0594 Protein kinase PCTAIRE and related kinases 154 2e-37
CE18009 [R] KOG0594 Protein kinase PCTAIRE and related kinases 154 2e-37
YPR161c [D] KOG0600 Cdc2-related protein kinase 154 3e-37
SPAC3C7.06c [T] KOG0661 MAPK related serine/threonine protein ki... 153 6e-37
7296451 [D] KOG0600 Cdc2-related protein kinase 152 1e-36
SPBPI064 [G] KOG0658 Glycogen synthase kinase-3 152 1e-36
YDL079c [G] KOG0658 Glycogen synthase kinase-3 151 2e-36
YNL307c [G] KOG0658 Glycogen synthase kinase-3 150 4e-36
YKL139w [D] KOG0600 Cdc2-related protein kinase 150 5e-36
Hs4502747 [D] KOG0669 Cyclin T-dependent kinase CDK9 150 5e-36
CE29612 [R] KOG0594 Protein kinase PCTAIRE and related kinases 149 6e-36
7302908 [R] KOG0594 Protein kinase PCTAIRE and related kinases 149 1e-35
CE19749 [T] KOG0665 Jun-N-terminal kinase (JNK) 147 2e-35
CE01761 [R] KOG0663 Protein kinase PITSLRE and related kinases 147 3e-35
Hs7706059 [R] KOG0593 Predicted protein kinase KKIAMRE 146 5e-35
Hs4503095 [TDK] KOG0668 Casein kinase II alpha subunit 146 7e-35
7296346 [R] KOG0663 Protein kinase PITSLRE and related kinases 146 7e-35
Hs7706549 [D] KOG0600 Cdc2-related protein kinase 145 9e-35
ECU11g0960 [D] KOG0600 Cdc2-related protein kinase 145 9e-35
SPBC32H8.10 [D] KOG0600 Cdc2-related protein kinase 145 1e-34
CE26988 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 145 1e-34
Hs17461944 [R] KOG0593 Predicted protein kinase KKIAMRE 145 2e-34
YDL108w [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 144 2e-34
Hs14110390 [D] KOG0600 Cdc2-related protein kinase 144 2e-34
Hs14110387 [D] KOG0600 Cdc2-related protein kinase 144 2e-34
CE08727 [G] KOG0658 Glycogen synthase kinase-3 144 3e-34
Hs18581346 [T] KOG0660 Mitogen-activated protein kinase 143 4e-34
ECU02g1450 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymer... 143 4e-34
7289745 [TDK] KOG0668 Casein kinase II alpha subunit 143 6e-34
YOL128c [G] KOG0658 Glycogen synthase kinase-3 142 1e-33
Hs4503097 [TDK] KOG0668 Casein kinase II alpha subunit 141 2e-33
CE28918 [R] KOG0594 Protein kinase PCTAIRE and related kinases 141 2e-33
CE18608 [R] KOG0594 Protein kinase PCTAIRE and related kinases 141 2e-33
ECU07g1270 [G] KOG0658 Glycogen synthase kinase-3 141 2e-33
7291442 [D] KOG0669 Cyclin T-dependent kinase CDK9 141 2e-33
SPBC8D2.19 [T] KOG0661 MAPK related serine/threonine protein kinase 140 3e-33
CE19219 [T] KOG0665 Jun-N-terminal kinase (JNK) 140 4e-33
CE03811 [R] KOG0663 Protein kinase PITSLRE and related kinases 140 4e-33
CE17321 [TDK] KOG0668 Casein kinase II alpha subunit 137 2e-32
7298142 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 137 4e-32
CE23751 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 135 2e-31
CE19878 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 135 2e-31
CE05897 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 135 2e-31
Hs7106269 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 134 3e-31
Hs20550209 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 134 3e-31
SPAC23H4.17c [K] KOG0666 Cyclin C-dependent kinase CDK8 133 5e-31
7294866 [K] KOG0666 Cyclin C-dependent kinase CDK8 133 5e-31
Hs5922004 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 132 8e-31
Hs4503427 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 132 8e-31
At2g23070 [TDK] KOG0668 Casein kinase II alpha subunit 132 1e-30
Hs4503429 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 131 2e-30
At3g50000 [TDK] KOG0668 Casein kinase II alpha subunit 131 2e-30
SPAC1D4.11c [T] KOG0671 LAMMER dual specificity kinases 130 3e-30
Hs17452757 [UT] KOG0662 Cyclin-dependent kinase CDK5 130 5e-30
CE05686 [A] KOG0670 U4/U6-associated splicing factor PRP4 129 1e-29
YPL042c [K] KOG0666 Cyclin C-dependent kinase CDK8 128 1e-29
At5g67380 [TDK] KOG0668 Casein kinase II alpha subunit 128 1e-29
ECU08g1790 [D] KOG0600 Cdc2-related protein kinase 128 2e-29
At2g23080 [TDK] KOG0668 Casein kinase II alpha subunit 128 2e-29
Hs16306492 [R] KOG0594 Protein kinase PCTAIRE and related kinases 125 1e-28
CE17815 [K] KOG0666 Cyclin C-dependent kinase CDK8 125 1e-28
Hs16936530 [R] KOG0594 Protein kinase PCTAIRE and related kinases 125 2e-28
SPAC23C11.11 [TDK] KOG0668 Casein kinase II alpha subunit 124 2e-28
Hs20551615 [K] KOG0666 Cyclin C-dependent kinase CDK8 124 2e-28
ECU05g1510 [TDK] KOG0668 Casein kinase II alpha subunit 124 3e-28
Hs4502745 [K] KOG0666 Cyclin C-dependent kinase CDK8 124 4e-28
7293496 [R] KOG0597 Serine-threonine protein kinase FUSED 122 1e-27
CE23826 [D] KOG0669 Cyclin T-dependent kinase CDK9 122 1e-27
CE18824 [D] KOG0669 Cyclin T-dependent kinase CDK9 122 1e-27
YOR061w [TDK] KOG0668 Casein kinase II alpha subunit 121 2e-27
At3g56760 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 119 7e-27
SPAC2F7.03c [R] KOG0667 Dual-specificity tyrosine-phosphorylatio... 119 9e-27
ECU08g0230 [R] KOG0594 Protein kinase PCTAIRE and related kinases 119 9e-27
CE09532 [G] KOG0658 Glycogen synthase kinase-3 119 1e-26
7291932 [A] KOG0670 U4/U6-associated splicing factor PRP4 118 2e-26
SPAC1E11.03 [R] KOG0667 Dual-specificity tyrosine-phosphorylatio... 118 2e-26
CE06352 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 118 2e-26
At3g53640 [A] KOG0670 U4/U6-associated splicing factor PRP4 118 2e-26
Hs17999535 [A] KOG0670 U4/U6-associated splicing factor PRP4 117 3e-26
At1g13350 [A] KOG0670 U4/U6-associated splicing factor PRP4 117 3e-26
Hs6005850 [D] KOG0615 Serine/threonine protein kinase Chk2 and r... 117 3e-26
At2g41140 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 117 3e-26
At3g25840 [A] KOG0670 U4/U6-associated splicing factor PRP4 116 6e-26
Hs18552621 [R] KOG0597 Serine-threonine protein kinase FUSED 116 8e-26
CE04173 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 116 8e-26
7298004 [G] KOG0658 Glycogen synthase kinase-3 116 8e-26
YJL141c [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 115 1e-25
At1g73460 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 115 1e-25
CE21615 [T] KOG0578 p21-activated serine/threonine protein kinase 115 1e-25
HsM7657627 [D] KOG0575 Polo-like serine/threonine protein kinase 114 2e-25
At5g35980 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 114 2e-25
Hs7662170 [R] KOG0611 Predicted serine/threonine protein kinase 114 4e-25
At3g49370 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 114 4e-25
At3g01090 [T] KOG0583 Serine/threonine protein kinase 114 4e-25
SPCC777.14 [A] KOG0670 U4/U6-associated splicing factor PRP4 113 5e-25
Hs21361433 [D] KOG0575 Polo-like serine/threonine protein kinase 113 5e-25
ECU11g0180 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 113 5e-25
At3g19100 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 113 5e-25
Hs4758008 [T] KOG0671 LAMMER dual specificity kinases 113 6e-25
Hs22045050 [T] KOG0671 LAMMER dual specificity kinases 113 6e-25
YJL106w [T] KOG0661 MAPK related serine/threonine protein kinase 112 8e-25
CE04172 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 112 8e-25
At1g50230 [R] KOG0597 Serine-threonine protein kinase FUSED 112 1e-24
7300149 [T] KOG0578 p21-activated serine/threonine protein kinase 112 1e-24
7298652 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 112 1e-24
SPBC1604.14c [T] KOG0578 p21-activated serine/threonine protein ... 112 1e-24
Hs5922001 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 112 1e-24
Hs5921999 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 112 1e-24
CE20405 [G] KOG0658 Glycogen synthase kinase-3 112 1e-24
At5g24430 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 112 1e-24
CE04430 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 111 2e-24
At3g17750 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 111 2e-24
Hs14771959 [T] KOG0578 p21-activated serine/threonine protein ki... 110 3e-24
CE05377 [G] KOG0658 Glycogen synthase kinase-3 110 4e-24
Hs9910476 [T] KOG0578 p21-activated serine/threonine protein kinase 109 7e-24
Hs4758128_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 109 7e-24
Hs5031975 [T] KOG0578 p21-activated serine/threonine protein kinase 109 9e-24
SPAC9G1.02 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 an... 108 1e-23
CE05866 [G] KOG0658 Glycogen synthase kinase-3 108 1e-23
At5g19450 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 108 1e-23
At2g40120 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 108 1e-23
At1g49580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 108 1e-23
YIL035c [TDK] KOG0668 Casein kinase II alpha subunit 108 2e-23
SPCC74.03c [T] KOG0583 Serine/threonine protein kinase 108 2e-23
YDR507c [D] KOG0588 Serine/threonine protein kinase 108 2e-23
SPBC17F3.02 [T] KOG0201 Serine/threonine protein kinase 108 2e-23
At4g23650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 108 2e-23
7298926 [T] KOG0578 p21-activated serine/threonine protein kinase 108 2e-23
SPCC18B5.11c [D] KOG0615 Serine/threonine protein kinase Chk2 an... 107 4e-23
Hs20479818 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 107 5e-23
At5g25110 [T] KOG0583 Serine/threonine protein kinase 107 5e-23
Hs4758016 [D] KOG0575 Polo-like serine/threonine protein kinase 106 8e-23
At2g17890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 106 8e-23
At1g73450 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 106 8e-23
Hs4505599 [T] KOG0578 p21-activated serine/threonine protein kinase 105 1e-22
Hs14728804 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 105 1e-22
Hs13430860 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 105 1e-22
CE19302_1 [G] KOG0658 Glycogen synthase kinase-3 105 1e-22
SPCC320.12c [D] KOG0580 Serine/threonine protein kinase 105 2e-22
SPBC12D12.04c [T] KOG0694 Serine/threonine protein kinase 105 2e-22
Hs4502553 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 105 2e-22
Hs19923468 [T] KOG4236 Serine/threonine protein kinase PKC mu/PK... 105 2e-22
Hs11386209 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 105 2e-22
At4g24740 [T] KOG0671 LAMMER dual specificity kinases 105 2e-22
At3g53570 [T] KOG0671 LAMMER dual specificity kinases 105 2e-22
7300435 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and r... 105 2e-22
Hs4758222 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 104 2e-22
Hs18765758 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 104 2e-22
Hs18765756 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 104 2e-22
Hs18765754 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 104 2e-22
Hs18765752 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 104 2e-22
Hs18765750 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 104 2e-22
ECU02g0550 [D] KOG0575 Polo-like serine/threonine protein kinase 104 2e-22
At5g10930 [T] KOG0583 Serine/threonine protein kinase 104 2e-22
At3g61960 [OUT] KOG0595 Serine/threonine-protein kinase involved... 104 2e-22
At4g04720 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 104 3e-22
At3g57530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 104 3e-22
At3g50530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 104 3e-22
At2g41860 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 104 3e-22
At2g37840 [OUT] KOG0595 Serine/threonine-protein kinase involved... 104 3e-22
7300559 [T] KOG4279 Serine/threonine protein kinase 104 3e-22
YJL095w [T] KOG0198 MEKK and related serine/threonine protein ki... 103 4e-22
Hs7662210 [OUT] KOG0595 Serine/threonine-protein kinase involved... 103 4e-22
Hs20149547 [T] KOG0603 Ribosomal protein S6 kinase 103 4e-22
Hs19923464 [T] KOG0577 Serine/threonine protein kinase 103 4e-22
YDR477w [T] KOG0583 Serine/threonine protein kinase 103 5e-22
At3g04530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 103 5e-22
At1g12580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 103 5e-22
7299438 [R] KOG0586 Serine/threonine protein kinase 103 5e-22
Hs4826684_1 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 103 5e-22
At5g01820 [T] KOG0583 Serine/threonine protein kinase 103 7e-22
At1g54510 [R] KOG0589 Serine/threonine protein kinase 103 7e-22
7303211 [T] KOG4717 Serine/threonine protein kinase 103 7e-22
CE06635 [Z] KOG0613 Projectin/twitchin and related proteins 102 9e-22
CE06634 [Z] KOG0613 Projectin/twitchin and related proteins 102 9e-22
At4g36070 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 102 9e-22
At3g29160 [T] KOG0583 Serine/threonine protein kinase 102 9e-22
At2g38490 [T] KOG0583 Serine/threonine protein kinase 102 9e-22
At2g25880 [D] KOG0580 Serine/threonine protein kinase 102 9e-22
YGL179c [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 102 1e-21
Hs14196445 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 102 1e-21
At4g18700 [T] KOG0583 Serine/threonine protein kinase 102 1e-21
At1g08650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 102 1e-21
Hs5174547 [T] KOG4279 Serine/threonine protein kinase 102 1e-21
Hs4759050 [T] KOG0603 Ribosomal protein S6 kinase 102 1e-21
Hs20127418 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase ... 102 1e-21
Hs19923570 [T] KOG0603 Ribosomal protein S6 kinase 102 1e-21
CE01612 [G] KOG0658 Glycogen synthase kinase-3 102 1e-21
At5g45820 [T] KOG0583 Serine/threonine protein kinase 102 1e-21
At5g39440 [T] KOG0583 Serine/threonine protein kinase 102 1e-21
At1g76040 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 102 1e-21
Hs6031180 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and... 101 2e-21
Hs5803088 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and... 101 2e-21
At4g04740 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 101 2e-21
At2g46700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 101 2e-21
Hs7657526 [T] KOG0603 Ribosomal protein S6 kinase 101 3e-21
Hs7382496 [T] KOG0578 p21-activated serine/threonine protein kinase 101 3e-21
At5g45810 [T] KOG0583 Serine/threonine protein kinase 101 3e-21
At2g30360 [T] KOG0583 Serine/threonine protein kinase 101 3e-21
7291976 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 101 3e-21
At5g01810 [T] KOG0583 Serine/threonine protein kinase 100 3e-21
At1g53570 [T] KOG0198 MEKK and related serine/threonine protein ... 100 3e-21
YFR014c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 100 4e-21
HsM5454174 [T] KOG0201 Serine/threonine protein kinase 100 4e-21
Hs5031689 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD... 100 4e-21
Hs21361358 [T] KOG0201 Serine/threonine protein kinase 100 4e-21
CE28251 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 100 4e-21
At4g32830 [D] KOG0580 Serine/threonine protein kinase 100 4e-21
SPCC576.15c [T] KOG0592 3-phosphoinositide-dependent protein kin... 100 6e-21
ECU08g1480 [R] KOG0586 Serine/threonine protein kinase 100 6e-21
CE28218 [D] KOG0588 Serine/threonine protein kinase 100 6e-21
7296450 [D] KOG0575 Polo-like serine/threonine protein kinase 100 6e-21
Hs7657214 [T] KOG0583 Serine/threonine protein kinase 100 7e-21
Hs4505601 [T] KOG0578 p21-activated serine/threonine protein kinase 100 7e-21
Hs21389587 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 100 7e-21
Hs14670383 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 100 7e-21
At5g04870 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 100 7e-21
At1g09000 [T] KOG0198 MEKK and related serine/threonine protein ... 100 7e-21
7293601 [T] KOG0577 Serine/threonine protein kinase 100 7e-21
YHL007c [T] KOG0578 p21-activated serine/threonine protein kinase 99 1e-20
YDR466w [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 99 1e-20
Hs4506075 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD... 99 1e-20
Hs20545245 [D] KOG0588 Serine/threonine protein kinase 99 1e-20
CE27297 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 99 1e-20
7304358 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 99 1e-20
SPBC4C3.11 [T] KOG0592 3-phosphoinositide-dependent protein kina... 99 1e-20
At1g50700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 99 1e-20
7292679 [G] KOG0599 Phosphorylase kinase gamma subunit 99 1e-20
7290249 [R] KOG0586 Serine/threonine protein kinase 99 1e-20
YDL101c [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 99 2e-20
Hs7706401 [T] KOG0577 Serine/threonine protein kinase 99 2e-20
Hs4759208 [T] KOG0577 Serine/threonine protein kinase 99 2e-20
Hs4557511 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 99 2e-20
CE21025 [D] KOG0580 Serine/threonine protein kinase 99 2e-20
CE27670 [T] KOG0578 p21-activated serine/threonine protein kinase 98 2e-20
CE24993 [D] KOG0669 Cyclin T-dependent kinase CDK9 98 2e-20
CE24516 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 98 2e-20
At3g10660 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 98 2e-20
7293666 [D] KOG0575 Polo-like serine/threonine protein kinase 98 2e-20
YKL101w [D] KOG0588 Serine/threonine protein kinase 98 3e-20
SPAC23C11.16 [D] KOG0575 Polo-like serine/threonine protein kinase 98 3e-20
SPAC1F3.02c [T] KOG0198 MEKK and related serine/threonine protei... 98 3e-20
Hs5453976 [T] KOG0694 Serine/threonine protein kinase 98 3e-20
Hs22035600 [T] KOG0576 Mitogen-activated protein kinase kinase k... 98 3e-20
CE09360 [Z] KOG0613 Projectin/twitchin and related proteins 98 3e-20
At5g66880 [T] KOG0583 Serine/threonine protein kinase 98 3e-20
At5g07070 [T] KOG0583 Serine/threonine protein kinase 98 3e-20
At2g17290 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 98 3e-20
Hs5730055 [D] KOG0575 Polo-like serine/threonine protein kinase 97 4e-20
YPL209c [D] KOG0580 Serine/threonine protein kinase 97 5e-20
HsM4759010 [T] KOG0576 Mitogen-activated protein kinase kinase k... 97 5e-20
CE17284 [T] KOG0583 Serine/threonine protein kinase 97 5e-20
At1g14000 [T] KOG0192 Tyrosine kinase specific for activated (GT... 97 5e-20
7302570 [R] KOG0586 Serine/threonine protein kinase 97 5e-20
CE20167 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD a... 97 6e-20
At5g58380 [T] KOG0583 Serine/threonine protein kinase 97 6e-20
YPL153c [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 96 8e-20
Hs9966875 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 96 8e-20
Hs4758702 [T] KOG4279 Serine/threonine protein kinase 96 8e-20
Hs13569922 [R] KOG0611 Predicted serine/threonine protein kinase 96 8e-20
Hs5453964 [T] KOG0583 Serine/threonine protein kinase 96 1e-19
CE25046 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 96 1e-19
CE03492 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 96 1e-19
At3g50500 [T] KOG0583 Serine/threonine protein kinase 96 1e-19
YOR233w [T] KOG0583 Serine/threonine protein kinase 96 1e-19
YOL016c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 96 1e-19
Hs4507831 [OUT] KOG0595 Serine/threonine-protein kinase involved... 96 1e-19
Hs22043888 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 96 1e-19
Hs15011880 [T] KOG0201 Serine/threonine protein kinase 96 1e-19
7299437 [R] KOG0586 Serine/threonine protein kinase 96 1e-19
YCR073c [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and r... 95 2e-19
SPAC9G1.09 [T] KOG0201 Serine/threonine protein kinase 95 2e-19
At4g30960 [T] KOG0583 Serine/threonine protein kinase 95 2e-19
At1g69220 [T] KOG0576 Mitogen-activated protein kinase kinase ki... 95 2e-19
At1g53165 [T] KOG0201 Serine/threonine protein kinase 95 2e-19
HsM4826916 [D] KOG0575 Polo-like serine/threonine protein kinase 95 2e-19
Hs21359873 [D] KOG0575 Polo-like serine/threonine protein kinase 95 2e-19
ECU07g0360 [D] KOG0580 Serine/threonine protein kinase 95 2e-19
At2g38910 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 95 2e-19
Hs4507275 [D] KOG0580 Serine/threonine protein kinase 94 3e-19
CE27768 [R] KOG0586 Serine/threonine protein kinase 94 3e-19
CE23838 [R] KOG0586 Serine/threonine protein kinase 94 3e-19
At2g45490 [D] KOG0580 Serine/threonine protein kinase 94 3e-19
Hs4507277_1 [R] KOG0589 Serine/threonine protein kinase 94 3e-19
Hs14993776 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 94 4e-19
CE02586 [T] KOG0696 Serine/threonine protein kinase 94 4e-19
At4g32660 [T] KOG0671 LAMMER dual specificity kinases 94 4e-19
At3g15220 [T] KOG0201 Serine/threonine protein kinase 94 4e-19
At2g35890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 94 4e-19
YHR102w [T] KOG0201 Serine/threonine protein kinase 94 5e-19
YAR019c [T] KOG0198 MEKK and related serine/threonine protein ki... 94 5e-19
SPCC162.10 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 94 5e-19
Hs20538863 [T] KOG4250 TANK binding protein kinase TBK1 94 5e-19
At4g28980 [R] KOG0594 Protein kinase PCTAIRE and related kinases 94 5e-19
Hs22050308_2 [T] KOG0198 MEKK and related serine/threonine prote... 94 5e-19
Hs4505695 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 93 9e-19
At4g40010 [T] KOG0583 Serine/threonine protein kinase 93 9e-19
7294537 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 93 9e-19
7294217 [D] KOG0588 Serine/threonine protein kinase 93 9e-19
HsM4507279 [D] KOG0580 Serine/threonine protein kinase 92 1e-18
Hs4759178 [D] KOG0580 Serine/threonine protein kinase 92 1e-18
Hs4759052 [T] KOG0603 Ribosomal protein S6 kinase 92 1e-18
Hs21361643 [T] KOG4717 Serine/threonine protein kinase 92 1e-18
Hs20070158 [T] KOG0201 Serine/threonine protein kinase 92 1e-18
Hs15451902 [T] KOG0576 Mitogen-activated protein kinase kinase k... 92 1e-18
CE27177 [T] KOG4279 Serine/threonine protein kinase 92 1e-18
CE21879 [D] KOG0590 Checkpoint kinase and related serine/threoni... 92 1e-18
>YLR113w [T] KOG0660 Mitogen-activated protein kinase
Length = 435
Score = 695 bits (1794), Expect = 0.0
Identities = 350/459 (76%), Positives = 374/459 (81%), Gaps = 43/459 (9%)
Query: 2 SNEEFIRTQIFGTVFEITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSV 61
+NEEFIRTQIFGTVFEITNRY +LNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFST+V
Sbjct: 3 TNEEFIRTQIFGTVFEITNRYNDLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTAV 62
Query: 62 LAKRTYRELKLLKHLRHENLICLEDIFLSPLEDIYFVTELQGTDLHRLLQTRPLEKQFVQ 121
LAKRTYRELKLLKHLRHENLICL+DIFLSPLEDIYFVTELQGTDLHRLLQTRPLEKQFVQ
Sbjct: 63 LAKRTYRELKLLKHLRHENLICLQDIFLSPLEDIYFVTELQGTDLHRLLQTRPLEKQFVQ 122
Query: 122 YFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQMTGYVSTRYY 181
YFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQMTGYVSTRYY
Sbjct: 123 YFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQMTGYVSTRYY 182
Query: 182 RAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVID 241
RAPEIMLTWQKY+VEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVI+
Sbjct: 183 RAPEIMLTWQKYDVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIN 242
Query: 242 TICSENTLKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPYL 301
TICSENTLKFVTSLPHRDP+PFS RF+ +EPDA+DLLEKMLVFDPKKRITAADALAHPY
Sbjct: 243 TICSENTLKFVTSLPHRDPIPFSERFKTVEPDAVDLLEKMLVFDPKKRITAADALAHPYS 302
Query: 302 SPYHDPTDEPIAEAKFDWNFNDADLPVDTWRVMMYSEILDFHQIG--DPQINTNATFDDX 359
+PYHDPTDEP+A+AKFDW+FNDADLPVDTWRVMMYSEILDFH+IG D QI+ +ATFDD
Sbjct: 303 APYHDPTDEPVADAKFDWHFNDADLPVDTWRVMMYSEILDFHKIGGSDGQIDISATFDDQ 362
Query: 360 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPPQAQVTPQQLEXXXXXXXXXXXXXX 419
QAQ Q
Sbjct: 363 VAAATAAAA---------------------------QAQAQAQAQVQLNMAAHSHNGAGT 395
Query: 420 IGPD--------------PANETLTNFANQADQYVSKFK 444
G D AN+T+T++ NQA QY ++F+
Sbjct: 396 TGNDHSDIAGGNKVSDHVAANDTITDYGNQAIQYANEFQ 434
>SPAC24B11.06c [T] KOG0660 Mitogen-activated protein kinase
Length = 349
Score = 594 bits (1531), Expect = e-169
Identities = 280/341 (82%), Positives = 313/341 (91%)
Query: 5 EFIRTQIFGTVFEITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAK 64
EFIRTQIFGT FEIT RY++L P+GMGAFGLVCSA D LT VA+KKIMKPFST VLAK
Sbjct: 3 EFIRTQIFGTCFEITTRYSDLQPIGMGAFGLVCSAKDQLTGMNVAVKKIMKPFSTPVLAK 62
Query: 65 RTYRELKLLKHLRHENLICLEDIFLSPLEDIYFVTELQGTDLHRLLQTRPLEKQFVQYFL 124
RTYRELKLLKHLRHEN+I L DIF+SP EDIYFVTEL GTDLHRLL +RPLE QF+QYFL
Sbjct: 63 RTYRELKLLKHLRHENIISLSDIFISPFEDIYFVTELLGTDLHRLLTSRPLETQFIQYFL 122
Query: 125 YQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQMTGYVSTRYYRAP 184
YQILRGLK+VHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQMTGYVSTRYYRAP
Sbjct: 123 YQILRGLKFVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQMTGYVSTRYYRAP 182
Query: 185 EIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTIC 244
EIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPG+DHV+QFSIIT+LLG+PP +VI+TIC
Sbjct: 183 EIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGRDHVNQFSIITELLGTPPMEVIETIC 242
Query: 245 SENTLKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPYLSPY 304
S+NTL+FV SLP ++ VPF+ +F+N +PDAIDLLEKMLVFDP+KRI+AADALAH YL+PY
Sbjct: 243 SKNTLRFVQSLPQKEKVPFAEKFKNADPDAIDLLEKMLVFDPRKRISAADALAHNYLAPY 302
Query: 305 HDPTDEPIAEAKFDWNFNDADLPVDTWRVMMYSEILDFHQI 345
HDPTDEP+A+ FDW+F D DLPV+TW+VMMYSE+L FH +
Sbjct: 303 HDPTDEPVADEVFDWSFQDNDLPVETWKVMMYSEVLSFHNM 343
>Hs20986512 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 372 bits (954), Expect = e-103
Identities = 180/349 (51%), Positives = 242/349 (68%), Gaps = 8/349 (2%)
Query: 1 MSNEE--FIRTQIFGTVFEITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFS 58
MS E F R ++ T++E+ RY NL+PVG GA+G VC+A DT T VA+KK+ +PF
Sbjct: 1 MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQ 60
Query: 59 TSVLAKRTYRELKLLKHLRHENLICLEDIF-----LSPLEDIYFVTELQGTDLHRLLQTR 113
+ + AKRTYREL+LLKH++HEN+I L D+F L D+Y VT L G DL+ +++ +
Sbjct: 61 SIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ 120
Query: 114 PLEKQFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQMT 173
L VQ+ +YQILRGLKY+HSA +IHRDLKPSN+ +NE+C+LKI DFGLAR D +MT
Sbjct: 121 KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMT 180
Query: 174 GYVSTRYYRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLG 233
GYV+TR+YRAPEIML W YN VDIWS GCI AE++ G+ LFPG DH+ Q +I L+G
Sbjct: 181 GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVG 240
Query: 234 SPPKDVIDTICSENTLKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAA 293
+P +++ I SE+ ++ SL + F++ F P A+DLLEKMLV D KRITAA
Sbjct: 241 TPGAELLKKISSESARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAA 300
Query: 294 DALAHPYLSPYHDPTDEPIAEAKFDWNFNDADLPVDTWRVMMYSEILDF 342
ALAH Y + YHDP DEP+A+ +D +F DL +D W+ + Y E++ F
Sbjct: 301 QALAHAYFAQYHDPDDEPVAD-PYDQSFESRDLLIDEWKSLTYDEVISF 348
>Hs4503069 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 369 bits (946), Expect = e-102
Identities = 180/349 (51%), Positives = 240/349 (68%), Gaps = 8/349 (2%)
Query: 1 MSNEE--FIRTQIFGTVFEITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFS 58
MS E F R ++ T++E+ RY NL+PVG GA+G VC+A DT T VA+KK+ +PF
Sbjct: 1 MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQ 60
Query: 59 TSVLAKRTYRELKLLKHLRHENLICLEDIF-----LSPLEDIYFVTELQGTDLHRLLQTR 113
+ + AKRTYREL+LLKH++HEN+I L D+F L D+Y VT L G DL+ +++ +
Sbjct: 61 SIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ 120
Query: 114 PLEKQFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQMT 173
L VQ+ +YQILRGLKY+HSA +IHRDLKPSN+ +NE+C+LKI DFGLAR D +MT
Sbjct: 121 KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMT 180
Query: 174 GYVSTRYYRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLG 233
GYV+TR+YRAPEIML W YN VDIWS GCI AE++ G+ LFPG DH++Q I L G
Sbjct: 181 GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLQQIMRLTG 240
Query: 234 SPPKDVIDTICSENTLKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAA 293
+PP +I+ + S ++ SL + F++ F P A+DLLEKMLV D KRITAA
Sbjct: 241 TPPAYLINRMPSHEARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAA 300
Query: 294 DALAHPYLSPYHDPTDEPIAEAKFDWNFNDADLPVDTWRVMMYSEILDF 342
ALAH Y + YHDP DEP+A+ +D +F DL +D W+ + Y E++ F
Sbjct: 301 QALAHAYFAQYHDPDDEPVAD-PYDQSFESRDLLIDEWKSLTYDEVISF 348
>7298087 [T] KOG0660 Mitogen-activated protein kinase
Length = 365
Score = 366 bits (939), Expect = e-101
Identities = 182/346 (52%), Positives = 236/346 (67%), Gaps = 9/346 (2%)
Query: 5 EFIRTQIFGTVFEITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAK 64
+F + I T +EI Y NL PVG GA+G VC A TS VAIKK+ +PF ++V AK
Sbjct: 7 KFYKLDINRTEWEIPETYQNLQPVGQGAYGQVCKAVVRGTSTKVAIKKLARPFQSAVHAK 66
Query: 65 RTYRELKLLKHLRHENLICLEDIF--------LSPLEDIYFVTELQGTDLHRLLQTRPLE 116
RTYREL+LLKH+ HEN+I L D+F L + +Y VT L DL+ +++T+ L
Sbjct: 67 RTYRELRLLKHMDHENVIGLLDVFHPGQPADSLDQFQQVYMVTHLMDADLNNIIRTQKLS 126
Query: 117 KQFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQMTGYV 176
VQ+ +YQILRGLKY+HSAGVIHRDLKPSNI +NE+C+L+I DFGLAR + +MTGYV
Sbjct: 127 DDHVQFLVYQILRGLKYIHSAGVIHRDLKPSNIAVNEDCELRILDFGLARPAESEMTGYV 186
Query: 177 STRYYRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPP 236
+TR+YRAPEIML W YN DIWS GCI AE++ G+ LFPG DH+HQ ++I ++LG+P
Sbjct: 187 ATRWYRAPEIMLNWMHYNQTADIWSVGCIMAELLTGRTLFPGTDHIHQLNLIMEVLGTPA 246
Query: 237 KDVIDTICSENTLKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADAL 296
+ + I SE+ ++ SLP F F+ P AIDLLEKML D KRITA AL
Sbjct: 247 DEFMSRISSESARNYIRSLPVMPRRNFRDIFRGANPLAIDLLEKMLELDADKRITAEQAL 306
Query: 297 AHPYLSPYHDPTDEPIAEAKFDWNFNDADLPVDTWRVMMYSEILDF 342
AHPY+ YHDPTDE A A +D +F + +LPV+ WR M++SE+ F
Sbjct: 307 AHPYMEKYHDPTDEQTA-ALYDQSFEENELPVEKWREMVFSEVTAF 351
>Hs20128774 [T] KOG0660 Mitogen-activated protein kinase
Length = 364
Score = 352 bits (904), Expect = 5e-97
Identities = 170/342 (49%), Positives = 235/342 (68%), Gaps = 6/342 (1%)
Query: 6 FIRTQIFGTVFEITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKR 65
F R ++ TV+E+ R L PVG GA+G VCSA D Q VA+KK+ +PF + + A+R
Sbjct: 8 FYRQELNKTVWEVPQRLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQSLIHARR 67
Query: 66 TYRELKLLKHLRHENLICLEDIF-----LSPLEDIYFVTELQGTDLHRLLQTRPLEKQFV 120
TYREL+LLKHL+HEN+I L D+F + ++Y VT L G DL+ +++ + L + V
Sbjct: 68 TYRELRLLKHLKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQALSDEHV 127
Query: 121 QYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQMTGYVSTRY 180
Q+ +YQ+LRGLKY+HSAG+IHRDLKPSN+ +NE+C+L+I DFGLAR D +MTGYV+TR+
Sbjct: 128 QFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEMTGYVATRW 187
Query: 181 YRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVI 240
YRAPEIML W YN VDIWS GCI AE+++GK LFPG D++ Q I +++G+P +V+
Sbjct: 188 YRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEVVGTPSPEVL 247
Query: 241 DTICSENTLKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPY 300
I SE+ ++ SLP SS F+ P AIDLL +MLV D +R++AA+ALAH Y
Sbjct: 248 AKISSEHARTYIQSLPPMPQKDLSSIFRGANPLAIDLLGRMLVLDSDQRVSAAEALAHAY 307
Query: 301 LSPYHDPTDEPIAEAKFDWNFNDADLPVDTWRVMMYSEILDF 342
S YHDP DEP AE +D + + ++ W+ + Y E+L F
Sbjct: 308 FSQYHDPEDEPEAE-PYDESVEAKERTLEEWKELTYQEVLSF 348
>7301110 [T] KOG0660 Mitogen-activated protein kinase
Length = 366
Score = 352 bits (903), Expect = 6e-97
Identities = 176/347 (50%), Positives = 237/347 (67%), Gaps = 9/347 (2%)
Query: 4 EEFIRTQIFGTVFEITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLA 63
++F + I T +EI + Y +L PVG GA+G V A T+ VAIKK+ +PF ++V A
Sbjct: 7 KKFYKLDINRTEWEIPDIYQDLQPVGSGAYGQVSKAVVRGTNMHVAIKKLARPFQSAVHA 66
Query: 64 KRTYRELKLLKHLRHENLICLEDIF--------LSPLEDIYFVTELQGTDLHRLLQTRPL 115
KRTYREL+LLKH+ HEN+I L DIF L + +Y VT L DL+ +++ + L
Sbjct: 67 KRTYRELRLLKHMDHENVIGLLDIFHPHPANGSLENFQQVYLVTHLMDADLNNIIRMQHL 126
Query: 116 EKQFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQMTGY 175
VQ+ +YQILRGLKY+HSAGVIHRDLKPSNI +NE+C+L+I DFGLAR + +MTGY
Sbjct: 127 SDDHVQFLVYQILRGLKYIHSAGVIHRDLKPSNIAVNEDCELRILDFGLARPTENEMTGY 186
Query: 176 VSTRYYRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSP 235
V+TR+YRAPEIML W Y+ VDIWS GCI AE+I + LFPG DH+HQ ++I ++LG+P
Sbjct: 187 VATRWYRAPEIMLNWMHYDQTVDIWSVGCIMAELITRRTLFPGTDHIHQLNLIMEMLGTP 246
Query: 236 PKDVIDTICSENTLKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADA 295
P + + I SE+ ++ SLP F + F+N P AIDLLEKML D +KRITA +A
Sbjct: 247 PAEFLKKISSESARSYIQSLPPMKGRSFKNVFKNANPLAIDLLEKMLELDAEKRITAEEA 306
Query: 296 LAHPYLSPYHDPTDEPIAEAKFDWNFNDADLPVDTWRVMMYSEILDF 342
L+HPYL Y +P+ E +D +F D DLPVD W+ ++Y E+ +F
Sbjct: 307 LSHPYLEKYAEPSVEQ-TSPPYDHSFEDMDLPVDKWKELIYKEVTNF 352
>At2g43790 [T] KOG0660 Mitogen-activated protein kinase
Length = 395
Score = 346 bits (887), Expect = 5e-95
Identities = 167/346 (48%), Positives = 241/346 (69%), Gaps = 9/346 (2%)
Query: 6 FIRTQIFGTVFEITNRYTN-LNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAK 64
FI+ IFG +FE+T +Y + P+G GA+G+VCSA ++ T++ VAIKKI F + AK
Sbjct: 46 FIQYNIFGNIFEVTAKYKPPIMPIGKGAYGIVCSAMNSETNESVAIKKIANAFDNKIDAK 105
Query: 65 RTYRELKLLKHLRHENLICLEDIFLSPLE----DIYFVTELQGTDLHRLLQT-RPLEKQF 119
RT RE+KLL+H+ HEN++ + DI PL D+Y EL TDLH+++++ + L ++
Sbjct: 106 RTLREIKLLRHMDHENIVAIRDIIPPPLRNAFNDVYIAYELMDTDLHQIIRSNQALSEEH 165
Query: 120 VQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARI--QDPQMTGYVS 177
QYFLYQILRGLKY+HSA V+HRDLKPSN+L+N NCDLKICDFGLAR+ + MT YV
Sbjct: 166 CQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARVTSESDFMTEYVV 225
Query: 178 TRYYRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPK 237
TR+YRAPE++L Y +D+WS GCIF E+++ KPLFPG+DHVHQ ++ +L+G+P +
Sbjct: 226 TRWYRAPELLLNSSDYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPSE 285
Query: 238 DVIDTICSENTLKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALA 297
+ ++ + +EN +++ LP + +F + P AIDL+EKML FDP++RIT DALA
Sbjct: 286 EELEFL-NENAKRYIRQLPPYPRQSITDKFPTVHPLAIDLIEKMLTFDPRRRITVLDALA 344
Query: 298 HPYLSPYHDPTDEPIAEAKFDWNFNDADLPVDTWRVMMYSEILDFH 343
HPYL+ HD +DEP F+++F + L + + ++Y E L F+
Sbjct: 345 HPYLNSLHDISDEPECTIPFNFDFENHALSEEQMKELIYREALAFN 390
>At3g45640 [T] KOG0660 Mitogen-activated protein kinase
Length = 370
Score = 345 bits (884), Expect = 1e-94
Identities = 168/344 (48%), Positives = 235/344 (67%), Gaps = 8/344 (2%)
Query: 5 EFIRTQIFGTVFEITNRYTN-LNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLA 63
+FI IFG++FEIT++Y + P+G GA+G+VCS DT T++ VA+KKI F + A
Sbjct: 20 QFISYDIFGSLFEITSKYRPPIIPIGRGAYGIVCSVLDTETNELVAMKKIANAFDNHMDA 79
Query: 64 KRTYRELKLLKHLRHENLICLEDIFLSPLE----DIYFVTELQGTDLHRLLQT-RPLEKQ 118
KRT RE+KLL+HL HEN+I + D+ PL D+Y TEL TDLH+++++ + L ++
Sbjct: 80 KRTLREIKLLRHLDHENIIAIRDVVPPPLRRQFSDVYISTELMDTDLHQIIRSNQSLSEE 139
Query: 119 FVQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLAR--IQDPQMTGYV 176
QYFLYQ+LRGLKY+HSA +IHRDLKPSN+L+N NCDLKICDFGLAR ++ MT YV
Sbjct: 140 HCQYFLYQLLRGLKYIHSANIIHRDLKPSNLLLNANCDLKICDFGLARPTSENDFMTEYV 199
Query: 177 STRYYRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPP 236
TR+YRAPE++L Y +D+WS GCIF E++ KPLFPGKDHVHQ ++T+LLG+P
Sbjct: 200 VTRWYRAPELLLNSSDYTAAIDVWSVGCIFMELMNRKPLFPGKDHVHQMRLLTELLGTPT 259
Query: 237 KDVIDTICSENTLKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADAL 296
+ + +E+ +++ LP+ P + F ++ P AIDL+++ML FDP +RIT AL
Sbjct: 260 ESDLGFTHNEDAKRYIRQLPNFPRQPLAKLFSHVNPMAIDLVDRMLTFDPNRRITVEQAL 319
Query: 297 AHPYLSPYHDPTDEPIAEAKFDWNFNDADLPVDTWRVMMYSEIL 340
H YL+ HDP DEPI + F + F L + + M+Y E +
Sbjct: 320 NHQYLAKLHDPNDEPICQKPFSFEFEQQPLDEEQIKEMIYQEAI 363
>Hs20986531 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 343 bits (879), Expect = 4e-94
Identities = 169/340 (49%), Positives = 232/340 (67%), Gaps = 11/340 (3%)
Query: 13 GTVFEITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKL 72
G VF++ RYTNL+ +G GA+G+VCSA D + VAIKKI PF +RT RE+K+
Sbjct: 16 GQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKI-SPFEHQTYCQRTLREIKI 74
Query: 73 LKHLRHENLICLEDIFLSP----LEDIYFVTELQGTDLHRLLQTRPLEKQFVQYFLYQIL 128
L RHEN+I + DI +P ++D+Y V +L TDL++LL+T+ L + YFLYQIL
Sbjct: 75 LLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQIL 134
Query: 129 RGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQ------MTGYVSTRYYR 182
RGLKY+HSA V+HRDLKPSN+L+N CDLKICDFGLAR+ DP +T YV+TR+YR
Sbjct: 135 RGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYR 194
Query: 183 APEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDT 242
APEIML + Y +DIWS GCI AEM+ +P+FPGK ++ Q + I +LGSP ++ ++
Sbjct: 195 APEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNC 254
Query: 243 ICSENTLKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPYLS 302
I + ++ SLPH++ VP++ F N + A+DLL+KML F+P KRI ALAHPYL
Sbjct: 255 IINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLE 314
Query: 303 PYHDPTDEPIAEAKFDWNFNDADLPVDTWRVMMYSEILDF 342
Y+DP+DEPIAEA F ++ DLP + + +++ E F
Sbjct: 315 QYYDPSDEPIAEAPFKFDMELDDLPKEKLKELIFEETARF 354
>Hs20986529 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 342 bits (878), Expect = 5e-94
Identities = 169/340 (49%), Positives = 231/340 (67%), Gaps = 11/340 (3%)
Query: 13 GTVFEITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKL 72
G VF++ RYTNL+ +G GA+G+VCSA D + VAIKKI PF +RT RE+K+
Sbjct: 16 GQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKI-SPFEHQTYCQRTLREIKI 74
Query: 73 LKHLRHENLICLEDIFLSP----LEDIYFVTELQGTDLHRLLQTRPLEKQFVQYFLYQIL 128
L RHEN+I + DI +P ++D+Y V +L TDL++LL+T+ L + YFLYQIL
Sbjct: 75 LLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQIL 134
Query: 129 RGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQ------MTGYVSTRYYR 182
RGLKY+HSA V+HRDLKPSN+L+N CDLKICDFGLAR+ DP +T YV+TR+YR
Sbjct: 135 RGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYR 194
Query: 183 APEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDT 242
APEIML + Y +DIWS GCI AEM+ +P+FPGK ++ Q I +LGSP ++ ++
Sbjct: 195 APEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLKHILGILGSPSQEDLNC 254
Query: 243 ICSENTLKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPYLS 302
I + ++ SLPH++ VP++ F N + A+DLL+KML F+P KRI ALAHPYL
Sbjct: 255 IINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLE 314
Query: 303 PYHDPTDEPIAEAKFDWNFNDADLPVDTWRVMMYSEILDF 342
Y+DP+DEPIAEA F ++ DLP + + +++ E F
Sbjct: 315 QYYDPSDEPIAEAPFKFDMELDDLPKEKLKELIFEETARF 354
>Hs4506785 [T] KOG0660 Mitogen-activated protein kinase
Length = 367
Score = 341 bits (875), Expect = 1e-93
Identities = 165/342 (48%), Positives = 225/342 (65%), Gaps = 6/342 (1%)
Query: 6 FIRTQIFGTVFEITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKR 65
F R ++ T +E+ Y +L PVG GA+G VCSA D T VAIKK+ +PF + + AKR
Sbjct: 11 FYRQEVTKTAWEVRAVYRDLQPVGSGAYGAVCSAVDGRTGAKVAIKKLYRPFQSELFAKR 70
Query: 66 TYRELKLLKHLRHENLICLEDIF-----LSPLEDIYFVTELQGTDLHRLLQTRPLEKQFV 120
YREL+LLKH+RHEN+I L D+F L D Y V GTDL +L++ L + +
Sbjct: 71 AYRELRLLKHMRHENVIGLLDVFTPDETLDDFTDFYLVMPFMGTDLGKLMKHEKLGEDRI 130
Query: 121 QYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQMTGYVSTRY 180
Q+ +YQ+L+GL+Y+H+AG+IHRDLKP N+ +NE+C+LKI DFGLAR D +MTGYV TR+
Sbjct: 131 QFLVYQMLKGLRYIHAAGIIHRDLKPGNLAVNEDCELKILDFGLARQADSEMTGYVVTRW 190
Query: 181 YRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVI 240
YRAPE++L W +Y VDIWS GCI AEMI GK LF G DH+ Q I + G+PP + +
Sbjct: 191 YRAPEVILNWMRYTQTVDIWSVGCIMAEMITGKTLFKGSDHLDQLKEIMKVTGTPPAEFV 250
Query: 241 DTICSENTLKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPY 300
+ S+ + LP + F+S N P A++LLEKMLV D ++R+TA +ALAHPY
Sbjct: 251 QRLQSDEAKNNMKGLPELEKKDFASILTNASPLAVNLLEKMLVLDAEQRVTAGEALAHPY 310
Query: 301 LSPYHDPTDEPIAEAKFDWNFNDADLPVDTWRVMMYSEILDF 342
HD DEP + K+D +F+D D +D W+ + Y E+L F
Sbjct: 311 FESLHDTEDEPQVQ-KYDDSFDDVDRTLDEWKRVTYKEVLSF 351
>At4g01370 [T] KOG0660 Mitogen-activated protein kinase
Length = 376
Score = 340 bits (872), Expect = 2e-93
Identities = 165/346 (47%), Positives = 236/346 (67%), Gaps = 8/346 (2%)
Query: 6 FIRTQIFGTVFEITNRYTN-LNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAK 64
+++ ++G +FE++ +Y L P+G GA+G+VC+AT++ T + VAIKKI F + AK
Sbjct: 26 YVQYNVYGNLFEVSRKYVPPLRPIGRGAYGIVCAATNSETGEEVAIKKIGNAFDNIIDAK 85
Query: 65 RTYRELKLLKHLRHENLICLEDIFLSP----LEDIYFVTELQGTDLHRLLQT-RPLEKQF 119
RT RE+KLLKH+ HEN+I ++DI P D+Y V EL TDLH+++++ +PL
Sbjct: 86 RTLREIKLLKHMDHENVIAVKDIIKPPQRENFNDVYIVYELMDTDLHQIIRSNQPLTDDH 145
Query: 120 VQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQ--MTGYVS 177
++FLYQ+LRGLKYVHSA V+HRDLKPSN+L+N NCDLK+ DFGLAR + MT YV
Sbjct: 146 CRFFLYQLLRGLKYVHSANVLHRDLKPSNLLLNANCDLKLGDFGLARTKSETDFMTEYVV 205
Query: 178 TRYYRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPK 237
TR+YRAPE++L +Y +DIWS GCI E + +PLFPGKD+VHQ +IT+L+GSP
Sbjct: 206 TRWYRAPELLLNCSEYTAAIDIWSVGCILGETMTREPLFPGKDYVHQLRLITELIGSPDD 265
Query: 238 DVIDTICSENTLKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALA 297
+ + S+N ++V LP F++RF N+ A+DLLEKMLVFDP +RIT +AL
Sbjct: 266 SSLGFLRSDNARRYVRQLPQYPRQNFAARFPNMSAGAVDLLEKMLVFDPSRRITVDEALC 325
Query: 298 HPYLSPYHDPTDEPIAEAKFDWNFNDADLPVDTWRVMMYSEILDFH 343
HPYL+P HD +EP+ F+++F L + + ++Y E + F+
Sbjct: 326 HPYLAPLHDINEEPVCVRPFNFDFEQPTLTEENIKELIYRETVKFN 371
>CE06686 [T] KOG0660 Mitogen-activated protein kinase
Length = 377
Score = 338 bits (868), Expect = 7e-93
Identities = 168/346 (48%), Positives = 230/346 (65%), Gaps = 6/346 (1%)
Query: 4 EEFIRTQIFGTVFEITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLA 63
E + ++ +V+ + N Y NL P+G GA+G VC+A T + VAIKK +PF + + A
Sbjct: 17 EGYYVVELNRSVWVVPNYYINLTPIGTGAYGTVCAAECTRSGTRVAIKKFNRPFQSIIHA 76
Query: 64 KRTYRELKLLKHLRHENLICLEDIF-----LSPLEDIYFVTELQGTDLHRLLQTRPLEKQ 118
+RTYREL+LL+ + HEN+I L D+F ++ +ED+YFV+ L G DL +L+ + L
Sbjct: 77 RRTYRELRLLRCMCHENIIDLLDVFTPNENVNDIEDVYFVSMLMGADLSNILKIQRLNDD 136
Query: 119 FVQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQMTGYVST 178
+Q+ +YQILRGLKY+HSA +IHRDLKPSNI +NE+C+LKI DFGLAR D +MTGYV+T
Sbjct: 137 HIQFLVYQILRGLKYIHSADIIHRDLKPSNIAVNEDCELKILDFGLARQTDSEMTGYVAT 196
Query: 179 RYYRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKD 238
R+YRAPEIML W Y VD+WS GCI AE+I GK LFPG DH+ Q + I + G+P ++
Sbjct: 197 RWYRAPEIMLNWMHYTQTVDVWSVGCILAELITGKTLFPGSDHIDQLTRIMSVTGTPDEE 256
Query: 239 VIDTICSENTLKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAH 298
+ I SE ++ +LP F F P AIDLLEKML DP +R TA +A+ H
Sbjct: 257 FLKKISSEEARNYIRNLPKMTRRDFKRLFAQATPQAIDLLEKMLHLDPDRRPTAKEAMEH 316
Query: 299 PYLSPYHDPTDEPIAEAKFDWNFNDADLPVDTWRVMMYSEILDFHQ 344
YL+ YHD TDEPIAE + D N + +D W+ +++ EI DF +
Sbjct: 317 EYLAAYHDETDEPIAE-EMDLNDDVRADTIDEWKKIIWEEISDFQK 361
>At1g07880 [T] KOG0660 Mitogen-activated protein kinase
Length = 363
Score = 334 bits (857), Expect = 1e-91
Identities = 167/345 (48%), Positives = 230/345 (66%), Gaps = 8/345 (2%)
Query: 6 FIRTQIFGTVFEITNRYTN-LNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAK 64
++ + G +FE++++Y + P+G GA+G+VC AT++ T++ VAIKKI F V AK
Sbjct: 16 YVMYNVLGNIFELSSKYIPPIEPIGRGAYGIVCCATNSETNEEVAIKKIANAFDNRVDAK 75
Query: 65 RTYRELKLLKHLRHENLICLEDIFLSP----LEDIYFVTELQGTDLHRLLQ-TRPLEKQF 119
RT RE+KLL H+ H+N+I ++DI P ED+Y V EL TDLH++++ T+ L
Sbjct: 76 RTLREIKLLSHMDHDNVIKIKDIIELPEKERFEDVYIVYELMDTDLHQIIRSTQTLTDDH 135
Query: 120 VQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQ--MTGYVS 177
QYFLYQILRGLKY+HSA V+HRDLKPSN+++N NCDLKICDFGLAR + MT YV
Sbjct: 136 CQYFLYQILRGLKYIHSANVLHRDLKPSNLVLNTNCDLKICDFGLARTSNETEIMTEYVV 195
Query: 178 TRYYRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPK 237
TR+YRAPE++L +Y +DIWS GCIF E++ + LFPGKD+V Q +IT+LLGSP
Sbjct: 196 TRWYRAPELLLNSSEYTGAIDIWSVGCIFMEILRRETLFPGKDYVQQLKLITELLGSPDD 255
Query: 238 DVIDTICSENTLKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALA 297
+D + S+N K+V LPH F +F N+ P A+DL EKMLVFDP KRIT +AL
Sbjct: 256 SDLDFLRSDNARKYVKQLPHVQKQSFREKFPNISPMALDLAEKMLVFDPSKRITVDEALK 315
Query: 298 HPYLSPYHDPTDEPIAEAKFDWNFNDADLPVDTWRVMMYSEILDF 342
PYL+ H+ +EP F ++F + L + +++ E L F
Sbjct: 316 QPYLASLHEINEEPTCPTPFSFDFEETALDEQDIKELVWRESLHF 360
>CE24971 [T] KOG0660 Mitogen-activated protein kinase
Length = 444
Score = 331 bits (848), Expect = 2e-90
Identities = 164/345 (47%), Positives = 226/345 (64%), Gaps = 11/345 (3%)
Query: 10 QIFGTVFEITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRE 69
++ G +FE+ RY NL+ +G GA+G+V SA DT+T VAIKKI PF +RT RE
Sbjct: 84 EVHGQLFEVAPRYVNLSYIGEGAYGMVASALDTITRDRVAIKKI-SPFEHQTFCQRTLRE 142
Query: 70 LKLLKHLRHENLICLEDIFLSP----LEDIYFVTELQGTDLHRLLQTRPLEKQFVQYFLY 125
+K+L +HEN+I +++I S L+DIY V L TDL++LL+T+ L V YFLY
Sbjct: 143 IKILNRFKHENIINIQEIIRSETVDSLKDIYIVQCLMETDLYKLLKTQKLSNDHVCYFLY 202
Query: 126 QILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQ------MTGYVSTR 179
QILRGLKY+HSA V+HRDLKPSN+L+N CDLKICDFGLAR+ DPQ +T YV+TR
Sbjct: 203 QILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVTDPQTDHTGFLTEYVATR 262
Query: 180 YYRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDV 239
+YRAPEIML + Y +D+WS GCI AEM+ +PLFPGK ++ Q ++I ++GSP
Sbjct: 263 WYRAPEIMLNSKGYTKSIDVWSVGCILAEMLSNRPLFPGKHYLDQLNLILAVVGSPSNAD 322
Query: 240 IDTICSENTLKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHP 299
+ I ++ ++ SLPH+ P++ + +P A+DLL+KML F+P RI ALAHP
Sbjct: 323 LQCIINDKARSYLISLPHKPKQPWARLYPGADPRALDLLDKMLTFNPHNRIDIEQALAHP 382
Query: 300 YLSPYHDPTDEPIAEAKFDWNFNDADLPVDTWRVMMYSEILDFHQ 344
YL Y+DP DEP+ E F DLP + + +++ E H+
Sbjct: 383 YLEQYYDPGDEPVCEEPFTLEMEFDDLPKEKLKELIWEEAEAHHR 427
>CE01583 [T] KOG0660 Mitogen-activated protein kinase
Length = 376
Score = 331 bits (848), Expect = 2e-90
Identities = 164/345 (47%), Positives = 226/345 (64%), Gaps = 11/345 (3%)
Query: 10 QIFGTVFEITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRE 69
++ G +FE+ RY NL+ +G GA+G+V SA DT+T VAIKKI PF +RT RE
Sbjct: 16 EVHGQLFEVAPRYVNLSYIGEGAYGMVASALDTITRDRVAIKKI-SPFEHQTFCQRTLRE 74
Query: 70 LKLLKHLRHENLICLEDIFLSP----LEDIYFVTELQGTDLHRLLQTRPLEKQFVQYFLY 125
+K+L +HEN+I +++I S L+DIY V L TDL++LL+T+ L V YFLY
Sbjct: 75 IKILNRFKHENIINIQEIIRSETVDSLKDIYIVQCLMETDLYKLLKTQKLSNDHVCYFLY 134
Query: 126 QILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQ------MTGYVSTR 179
QILRGLKY+HSA V+HRDLKPSN+L+N CDLKICDFGLAR+ DPQ +T YV+TR
Sbjct: 135 QILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVTDPQTDHTGFLTEYVATR 194
Query: 180 YYRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDV 239
+YRAPEIML + Y +D+WS GCI AEM+ +PLFPGK ++ Q ++I ++GSP
Sbjct: 195 WYRAPEIMLNSKGYTKSIDVWSVGCILAEMLSNRPLFPGKHYLDQLNLILAVVGSPSNAD 254
Query: 240 IDTICSENTLKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHP 299
+ I ++ ++ SLPH+ P++ + +P A+DLL+KML F+P RI ALAHP
Sbjct: 255 LQCIINDKARSYLISLPHKPKQPWARLYPGADPRALDLLDKMLTFNPHNRIDIEQALAHP 314
Query: 300 YLSPYHDPTDEPIAEAKFDWNFNDADLPVDTWRVMMYSEILDFHQ 344
YL Y+DP DEP+ E F DLP + + +++ E H+
Sbjct: 315 YLEQYYDPGDEPVCEEPFTLEMEFDDLPKEKLKELIWEEAEAHHR 359
>At3g59790 [T] KOG0660 Mitogen-activated protein kinase
Length = 393
Score = 329 bits (843), Expect = 6e-90
Identities = 163/346 (47%), Positives = 236/346 (68%), Gaps = 9/346 (2%)
Query: 6 FIRTQIFGTVFEITNRYTN-LNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAK 64
+I+ +FG +FE+ +Y + P+G GA G+VCSA D+ T++ VAIKKI + F ++ AK
Sbjct: 43 YIQYNLFGHIFELPAKYKPPIRPIGRGACGIVCSAVDSETNEKVAIKKITQVFDNTIEAK 102
Query: 65 RTYRELKLLKHLRHENLICLEDIFLSP----LEDIYFVTELQGTDLHRLLQT-RPLEKQF 119
RT RE+KLL+H HEN++ + D+ L P ED+Y V EL DL+R L++ + L K
Sbjct: 103 RTLREIKLLRHFDHENIVAIRDVILPPQRDSFEDVYIVNELMEFDLYRTLKSDQELTKDH 162
Query: 120 VQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARI--QDPQMTGYVS 177
YF+YQILRGLKY+HSA V+HRDLKPSN+L++ CDLKICDFGLAR + MT YV
Sbjct: 163 GMYFMYQILRGLKYIHSANVLHRDLKPSNLLLSTQCDLKICDFGLARATPESNLMTEYVV 222
Query: 178 TRYYRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPK 237
TR+YRAPE++L Y +D+WS GCIF E++ +PLFPGKD V+Q ++ +L+G+P +
Sbjct: 223 TRWYRAPELLLGSSDYTAAIDVWSVGCIFMEIMNREPLFPGKDQVNQLRLLLELIGTPSE 282
Query: 238 DVIDTICSENTLKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALA 297
+ + ++ SE +++ LP F+ +F N+ P AIDL+EKML FDPK+RI+ +ALA
Sbjct: 283 EELGSL-SEYAKRYIRQLPTLPRQSFTEKFPNVPPLAIDLVEKMLTFDPKQRISVKEALA 341
Query: 298 HPYLSPYHDPTDEPIAEAKFDWNFNDADLPVDTWRVMMYSEILDFH 343
HPYLS +HD TDEP F+++ ++ + +R ++Y E L F+
Sbjct: 342 HPYLSSFHDITDEPECSEPFNFDLDEHPFSEEQFRELIYCEALAFN 387
>At4g11330 [T] KOG0660 Mitogen-activated protein kinase
Length = 373
Score = 327 bits (837), Expect = 3e-89
Identities = 167/348 (47%), Positives = 233/348 (65%), Gaps = 11/348 (3%)
Query: 6 FIRTQIFGTVFEITNRYTN-LNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAK 64
+ + ++G +FE++N+Y + P+G GA L + D+ T + +AIKKI K F V AK
Sbjct: 26 YFQYNVYGNLFEVSNKYVPPIRPIGRGASVL---SVDSETHEEIAIKKIGKAFDNKVDAK 82
Query: 65 RTYRELKLLKHLRHENLICLEDIFLSPLE----DIYFVTELQGTDLHRLLQT-RPLEKQF 119
RT RE+KLL+HL HEN++ ++DI P + D+Y V EL TDLH+++++ + L
Sbjct: 83 RTLREIKLLRHLEHENVVVIKDIIRPPKKEDFVDVYIVFELMDTDLHQIIRSNQSLNDDH 142
Query: 120 VQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARI--QDPQMTGYVS 177
QYFLYQILRGLKY+HSA V+HRDLKPSN+L+N NCDLKI DFGLAR + MT YV
Sbjct: 143 CQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNSNCDLKITDFGLARTTSETEYMTEYVV 202
Query: 178 TRYYRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPK 237
TR+YRAPE++L +Y +D+WS GCIFAE++ +PLFPGKD+VHQ +IT+L+GSP
Sbjct: 203 TRWYRAPELLLNSSEYTSAIDVWSVGCIFAEIMTREPLFPGKDYVHQLKLITELIGSPDG 262
Query: 238 DVIDTICSENTLKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALA 297
++ + S N K+V LP FS+RF ++ AIDLLEKMLVFDP KRIT +AL
Sbjct: 263 ASLEFLRSANARKYVKELPKFPRQNFSARFPSMNSTAIDLLEKMLVFDPVKRITVEEALC 322
Query: 298 HPYLSPYHDPTDEPIAEAKFDWNFNDADLPVDTWRVMMYSEILDFHQI 345
+PYLS HD DEP+ F ++F D + + +++ E + F+ +
Sbjct: 323 YPYLSALHDLNDEPVCSNHFSFHFEDPSSTEEEIKELVWLESVKFNPL 370
>SPAC31G5.09c [T] KOG0660 Mitogen-activated protein kinase
Length = 372
Score = 324 bits (831), Expect = 1e-88
Identities = 165/338 (48%), Positives = 222/338 (64%), Gaps = 15/338 (4%)
Query: 16 FEITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKH 75
FE+ Y +N +G GA+G+VC+A + VA+KKI PF+ V RT RE+KLL+H
Sbjct: 33 FELPEEYEMINLIGQGAYGVVCAALHKPSGLKVAVKKI-HPFNHPVFCLRTLREIKLLRH 91
Query: 76 LRHENLICLEDIFLSP----LEDIYFVTELQGTDLHRLLQTRPLEKQFVQYFLYQILRGL 131
RHEN+I + DI P LED+Y V EL TDL+R+++++PL QYF YQILR L
Sbjct: 92 FRHENIISILDILPPPSYQELEDVYIVQELMETDLYRVIRSQPLSDDHCQYFTYQILRAL 151
Query: 132 KYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQ------MTGYVSTRYYRAPE 185
K +HSAGV+HRDLKPSN+L+N NCDLK+ DFGLAR Q MT YV+TR+YRAPE
Sbjct: 152 KAMHSAGVVHRDLKPSNLLLNANCDLKVADFGLARSTTAQGGNPGFMTEYVATRWYRAPE 211
Query: 186 IMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICS 245
IML++++Y+ +D+WS GCI AEM+ +PLFPGKD+ Q ++I ++LG+P D I S
Sbjct: 212 IMLSFREYSKAIDLWSTGCILAEMLSARPLFPGKDYHSQITLILNILGTPTMDDFSRIKS 271
Query: 246 ENTLKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPYLSPYH 305
K++ SLP V F + F PDAIDLLEK+L F+P KRITA +AL HPY++ YH
Sbjct: 272 ARARKYIKSLPFTPKVSFKALFPQASPDAIDLLEKLLTFNPDKRITAEEALKHPYVAAYH 331
Query: 306 DPTDEPIAEAK----FDWNFNDADLPVDTWRVMMYSEI 339
D +DEP A D N DL + + +++ E+
Sbjct: 332 DASDEPTASPMPPNLVDLYCNKEDLEIPVLKALIFREV 369
>Hs20562757 [T] KOG0660 Mitogen-activated protein kinase
Length = 379
Score = 322 bits (824), Expect = 9e-88
Identities = 162/340 (47%), Positives = 223/340 (64%), Gaps = 11/340 (3%)
Query: 13 GTVFEITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKL 72
G F++ RYT L +G GA+G+V SA D + VAIKKI PF +RT RE+++
Sbjct: 33 GQPFDVGPRYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKI-SPFEHQTYCQRTLREIQI 91
Query: 73 LKHLRHENLICLEDIF----LSPLEDIYFVTELQGTDLHRLLQTRPLEKQFVQYFLYQIL 128
L RHEN+I + DI L + D+Y V +L TDL++LL+++ L + YFLYQIL
Sbjct: 92 LLRFRHENVIGIRDILRASTLEAMRDVYIVQDLMETDLYKLLKSQQLSNDHICYFLYQIL 151
Query: 129 RGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQ------MTGYVSTRYYR 182
RGLKY+HSA V+HRDLKPSN+LIN CDLKICDFGLARI DP+ +T YV+TR+YR
Sbjct: 152 RGLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYR 211
Query: 183 APEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDT 242
APEIML + Y +DIWS GCI AEM+ +P+FPGK ++ Q + I +LGSP ++ ++
Sbjct: 212 APEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNC 271
Query: 243 ICSENTLKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPYLS 302
I + ++ SLP + V ++ F + A+DLL++ML F+P KRIT +ALAHPYL
Sbjct: 272 IINMKARNYLQSLPSKTKVAWAKLFPKSDSKALDLLDRMLTFNPNKRITVEEALAHPYLE 331
Query: 303 PYHDPTDEPIAEAKFDWNFNDADLPVDTWRVMMYSEILDF 342
Y+DPTDEP+AE F + DLP + + +++ E F
Sbjct: 332 QYYDPTDEPVAEEPFTFAMELDDLPKERLKELIFQETARF 371
>Hs4506085 [T] KOG0660 Mitogen-activated protein kinase
Length = 365
Score = 319 bits (818), Expect = 5e-87
Identities = 159/345 (46%), Positives = 217/345 (62%), Gaps = 6/345 (1%)
Query: 6 FIRTQIFGTVFEITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKR 65
F + + T +E+ Y + VG GA+G VCSA D + + VAIKK+ +PF + + AKR
Sbjct: 9 FYKQDVNKTAWELPKTYVSPTHVGSGAYGSVCSAIDKRSGEKVAIKKLSRPFQSEIFAKR 68
Query: 66 TYRELKLLKHLRHENLICLEDIF-----LSPLEDIYFVTELQGTDLHRLLQTRPLEKQFV 120
YREL LLKH++HEN+I L D+F L D Y V TDL +++ E++ +
Sbjct: 69 AYRELLLLKHMQHENVIGLLDVFTPASSLRNFYDFYLVMPFMQTDLQKIMGMEFSEEK-I 127
Query: 121 QYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQMTGYVSTRY 180
QY +YQ+L+GLKY+HSAGV+HRDLKP N+ +NE+C+LKI DFGLAR D +MTGYV TR+
Sbjct: 128 QYLVYQMLKGLKYIHSAGVVHRDLKPGNLAVNEDCELKILDFGLARHADAEMTGYVVTRW 187
Query: 181 YRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVI 240
YRAPE++L+W YN VDIWS GCI AEM+ GK LF GKD++ Q + I + G P + +
Sbjct: 188 YRAPEVILSWMHYNQTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILKVTGVPGTEFV 247
Query: 241 DTICSENTLKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPY 300
+ + ++ SLP F+ F P A DLLEKML D KR+TAA AL HP+
Sbjct: 248 QKLNDKAAKSYIQSLPQTPRKDFTQLFPRASPQAADLLEKMLELDVDKRLTAAQALTHPF 307
Query: 301 LSPYHDPTDEPIAEAKFDWNFNDADLPVDTWRVMMYSEILDFHQI 345
P+ DP +E A+ FD + L VD W+ +Y EI++F I
Sbjct: 308 FEPFRDPEEETEAQQPFDDSLEHEKLTVDEWKQHIYKEIVNFSPI 352
>At1g59580 [T] KOG0660 Mitogen-activated protein kinase
Length = 376
Score = 318 bits (814), Expect = 1e-86
Identities = 153/339 (45%), Positives = 230/339 (67%), Gaps = 9/339 (2%)
Query: 14 TVFEITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLL 73
T+FEI +Y + P+G GA+G+VCS+ + +++ VAIKKI F + A RT RELKLL
Sbjct: 24 TLFEIDTKYVPIKPIGRGAYGVVCSSVNRESNERVAIKKIHNVFENRIDALRTLRELKLL 83
Query: 74 KHLRHENLICLEDIFLS----PLEDIYFVTELQGTDLHRLLQT-RPLEKQFVQYFLYQIL 128
+HLRHEN++ L+D+ ++ +D+Y V EL TDLH+++++ + L QYFL+Q+L
Sbjct: 84 RHLRHENVVALKDVMMANHKRSFKDVYLVYELMDTDLHQIIKSSQVLSNDHCQYFLFQLL 143
Query: 129 RGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQ---MTGYVSTRYYRAPE 185
RGLKY+HSA ++HRDLKP N+L+N NCDLKICDFGLAR + + MT YV TR+YRAPE
Sbjct: 144 RGLKYIHSANILHRDLKPGNLLVNANCDLKICDFGLARTSNTKGQFMTEYVVTRWYRAPE 203
Query: 186 IMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICS 245
++L Y +D+WS GCIFAE++ KP+FPG + ++Q +I ++LGS ++ ++ I +
Sbjct: 204 LLLCCDNYGTSIDVWSVGCIFAELLGRKPVFPGTECLNQIKLIINILGSQREEDLEFIDN 263
Query: 246 ENTLKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPYLSPYH 305
+++ SLP+ + FS + AIDLL+KMLV DP KRI+ +AL HPY++P +
Sbjct: 264 PKAKRYIESLPYSPGISFSRLYPGANVLAIDLLQKMLVLDPSKRISVTEALQHPYMAPLY 323
Query: 306 DPTDEPIAEAKFDWNFN-DADLPVDTWRVMMYSEILDFH 343
DP+ P A+ D + + D DL + R +M+ E++ +H
Sbjct: 324 DPSANPPAQVPIDLDVDEDEDLGAEMIRELMWKEMIHYH 362
>At1g10210 [T] KOG0660 Mitogen-activated protein kinase
Length = 370
Score = 317 bits (812), Expect = 2e-86
Identities = 158/347 (45%), Positives = 233/347 (66%), Gaps = 13/347 (3%)
Query: 14 TVFEITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLL 73
T+FEI +Y + P+G GA+G+VCS+ ++ T++ VAIKKI + + A RT RELKLL
Sbjct: 24 TLFEIDTKYMPIKPIGRGAYGVVCSSVNSDTNEKVAIKKIHNVYENRIDALRTLRELKLL 83
Query: 74 KHLRHENLICLEDIFLS----PLEDIYFVTELQGTDLHRLLQT-RPLEKQFVQYFLYQIL 128
+HLRHEN+I L+D+ + +D+Y V EL TDLH+++++ + L QYFL+Q+L
Sbjct: 84 RHLRHENVIALKDVMMPIHKMSFKDVYLVYELMDTDLHQIIKSSQVLSNDHCQYFLFQLL 143
Query: 129 RGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQ---MTGYVSTRYYRAPE 185
RGLKY+HSA ++HRDLKP N+L+N NCDLKICDFGLAR + + MT YV TR+YRAPE
Sbjct: 144 RGLKYIHSANILHRDLKPGNLLVNANCDLKICDFGLARASNTKGQFMTEYVVTRWYRAPE 203
Query: 186 IMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICS 245
++L Y +D+WS GCIFAE++ KP+F G + ++Q +I ++LGS ++ ++ I +
Sbjct: 204 LLLCCDNYGTSIDVWSVGCIFAELLGRKPIFQGTECLNQLKLIVNILGSQREEDLEFIDN 263
Query: 246 ENTLKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPYLSPYH 305
+++ SLP+ + S + AIDLL+KMLVFDP KRI+ ++AL HPY++P +
Sbjct: 264 PKAKRYIRSLPYSPGMSLSRLYPGAHVLAIDLLQKMLVFDPSKRISVSEALQHPYMAPLY 323
Query: 306 DPTDEPIAEAKFDWNFNDADLPVDTWRVMMYSEILDFHQIGDPQINT 352
DP P A+ D + D DL + R MM++E+L +H PQ +T
Sbjct: 324 DPNANPPAQVPIDLDV-DEDLREEMIREMMWNEMLHYH----PQAST 365
>At2g46070 [T] KOG0660 Mitogen-activated protein kinase
Length = 406
Score = 314 bits (805), Expect = 1e-85
Identities = 154/346 (44%), Positives = 227/346 (65%), Gaps = 8/346 (2%)
Query: 6 FIRTQIFGTVFEITNRYTN-LNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAK 64
+++ ++G +FE++ +Y + P+G GA G+VC+A +++T + VAIKKI F + AK
Sbjct: 58 YVQYNVYGQLFEVSRKYVPPIRPIGRGACGIVCAAVNSVTGEKVAIKKIGNAFDNIIDAK 117
Query: 65 RTYRELKLLKHLRHENLICLEDIFLSP----LEDIYFVTELQGTDLHRLLQT-RPLEKQF 119
RT RE+KLL+H+ HEN+I ++DI P D+Y V EL TDL R+L++ + L
Sbjct: 118 RTLREIKLLRHMDHENVITIKDIVRPPQRDIFNDVYIVYELMDTDLQRILRSNQTLTSDQ 177
Query: 120 VQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQ--MTGYVS 177
++ +YQ+LRGLKYVHSA ++HRDL+PSN+L+N +LKI DFGLAR MT YV
Sbjct: 178 CRFLVYQLLRGLKYVHSANILHRDLRPSNVLLNSKNELKIGDFGLARTTSDTDFMTEYVV 237
Query: 178 TRYYRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPK 237
TR+YRAPE++L +Y +DIWS GCI E++ G+PLFPGKD+VHQ +IT+L+GSP
Sbjct: 238 TRWYRAPELLLNCSEYTAAIDIWSVGCILGEIMTGQPLFPGKDYVHQLRLITELVGSPDN 297
Query: 238 DVIDTICSENTLKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALA 297
+ + S+N ++V LP F++RF + AIDLLE+MLVFDP +RI+ +AL
Sbjct: 298 SSLGFLRSDNARRYVRQLPRYPKQQFAARFPKMPTTAIDLLERMLVFDPNRRISVDEALG 357
Query: 298 HPYLSPYHDPTDEPIAEAKFDWNFNDADLPVDTWRVMMYSEILDFH 343
H YLSP+HD EP+ F ++F + + ++Y E + F+
Sbjct: 358 HAYLSPHHDVAKEPVCSTPFSFDFEHPSCTEEHIKELIYKESVKFN 403
>Hs20986501 [T] KOG0660 Mitogen-activated protein kinase
Length = 816
Score = 314 bits (804), Expect = 2e-85
Identities = 161/354 (45%), Positives = 228/354 (63%), Gaps = 13/354 (3%)
Query: 3 NEEFIRTQIFGTVFEITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVL 62
N ++ + F F++ + Y + +G GA+G+V SA LT Q VAIKKI F
Sbjct: 36 NLALLKARSFDVTFDVGDEYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTN 95
Query: 63 AKRTYRELKLLKHLRHENLICLEDIF-----LSPLEDIYFVTELQGTDLHRLLQT-RPLE 116
AKRT RELK+LKH +H+N+I ++DI + +Y V +L +DLH+++ + +PL
Sbjct: 96 AKRTLRELKILKHFKHDNIIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQPLT 155
Query: 117 KQFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLAR--IQDPQ--- 171
+ V+YFLYQ+LRGLKY+HSA VIHRDLKPSN+L+NENC+LKI DFG+AR P
Sbjct: 156 LEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQ 215
Query: 172 --MTGYVSTRYYRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIIT 229
MT YV+TR+YRAPE+ML+ +Y +D+WS GCIF EM+ + LFPGK++VHQ +I
Sbjct: 216 YFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIM 275
Query: 230 DLLGSPPKDVIDTICSENTLKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKR 289
+LG+P VI + +E ++ SLP R PVP+ + + + A+ LL +ML F+P R
Sbjct: 276 MVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQALSLLGRMLRFEPSAR 335
Query: 290 ITAADALAHPYLSPYHDPTDEPIAEAKFDWNFNDADLPVDTWRVMMYSEILDFH 343
I+AA AL HP+L+ YHDP DEP FD+ F+ L + + + +EI DFH
Sbjct: 336 ISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKEAIVAEIEDFH 389
>Hs20986497 [T] KOG0660 Mitogen-activated protein kinase
Length = 816
Score = 314 bits (804), Expect = 2e-85
Identities = 161/354 (45%), Positives = 228/354 (63%), Gaps = 13/354 (3%)
Query: 3 NEEFIRTQIFGTVFEITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVL 62
N ++ + F F++ + Y + +G GA+G+V SA LT Q VAIKKI F
Sbjct: 36 NLALLKARSFDVTFDVGDEYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTN 95
Query: 63 AKRTYRELKLLKHLRHENLICLEDIF-----LSPLEDIYFVTELQGTDLHRLLQT-RPLE 116
AKRT RELK+LKH +H+N+I ++DI + +Y V +L +DLH+++ + +PL
Sbjct: 96 AKRTLRELKILKHFKHDNIIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQPLT 155
Query: 117 KQFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLAR--IQDPQ--- 171
+ V+YFLYQ+LRGLKY+HSA VIHRDLKPSN+L+NENC+LKI DFG+AR P
Sbjct: 156 LEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQ 215
Query: 172 --MTGYVSTRYYRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIIT 229
MT YV+TR+YRAPE+ML+ +Y +D+WS GCIF EM+ + LFPGK++VHQ +I
Sbjct: 216 YFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIM 275
Query: 230 DLLGSPPKDVIDTICSENTLKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKR 289
+LG+P VI + +E ++ SLP R PVP+ + + + A+ LL +ML F+P R
Sbjct: 276 MVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQALSLLGRMLRFEPSAR 335
Query: 290 ITAADALAHPYLSPYHDPTDEPIAEAKFDWNFNDADLPVDTWRVMMYSEILDFH 343
I+AA AL HP+L+ YHDP DEP FD+ F+ L + + + +EI DFH
Sbjct: 336 ISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKEAIVAEIEDFH 389
>At2g18170 [T] KOG0660 Mitogen-activated protein kinase
Length = 368
Score = 307 bits (787), Expect = 2e-83
Identities = 156/338 (46%), Positives = 221/338 (65%), Gaps = 9/338 (2%)
Query: 14 TVFEITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLL 73
T+FEI +Y + P+G GA+G+VCS+ + T++ VAIKKI F V A RT RELKLL
Sbjct: 24 TLFEIDTKYVPIKPIGRGAYGVVCSSINRETNERVAIKKIHNVFENRVDALRTLRELKLL 83
Query: 74 KHLRHENLICLEDIFL----SPLEDIYFVTELQGTDLHRLLQT-RPLEKQFVQYFLYQIL 128
+H+RHEN+I L+D+ L S +D+Y V EL TDLH+++++ + L +YFL+Q+L
Sbjct: 84 RHVRHENVIALKDVMLPANRSSFKDVYLVYELMDTDLHQIIKSSQSLSDDHCKYFLFQLL 143
Query: 129 RGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQ---MTGYVSTRYYRAPE 185
RGLKY+HSA ++HRDLKP N+L+N NCDLKICDFGLAR MT YV TR+YRAPE
Sbjct: 144 RGLKYLHSANILHRDLKPGNLLVNANCDLKICDFGLARTSQGNEQFMTEYVVTRWYRAPE 203
Query: 186 IMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICS 245
++L Y +D+WS GCIFAE++ KP+FPG + ++Q +I +++GS + I I +
Sbjct: 204 LLLCCDNYGTSIDVWSVGCIFAEILGRKPIFPGTECLNQLKLIINVVGSQQESDIRFIDN 263
Query: 246 ENTLKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPYLSPYH 305
+F+ SLP+ S+ + P AIDLL++MLVFDP KRI+ DAL HPY++
Sbjct: 264 PKARRFIKSLPYSRGTHLSNLYPQANPLAIDLLQRMLVFDPTKRISVTDALLHPYMAGLF 323
Query: 306 DPTDEPIAEAKFDWNFNDADLPVDTWRVMMYSEILDFH 343
DP P A + D ++ R MM++E+L +H
Sbjct: 324 DPGSNPPAHVPISLDI-DENMEEPVIREMMWNEMLYYH 360
>YHR030c [T] KOG0660 Mitogen-activated protein kinase
Length = 484
Score = 305 bits (780), Expect = 1e-82
Identities = 156/349 (44%), Positives = 227/349 (64%), Gaps = 17/349 (4%)
Query: 10 QIFGTVFEITNRYTNLNPVGMGAFGLVCSA--TDTLTSQPVAIKKIMKPFSTSVLAKRTY 67
++F F + R+ + +G GA+G+VCSA + VAIKK+ FS ++L KR+
Sbjct: 11 KVFNQDFSVDKRFQLIKEIGHGAYGIVCSARFAEAAEDTTVAIKKVTNVFSKTLLCKRSL 70
Query: 68 RELKLLKHLR-HENLICLEDIFL-----SPLEDIYFVTELQGTDLHRLLQT-RPLEKQFV 120
RELKLL+H R H+N+ CL D+ + + +Y EL D+H+++++ +PL
Sbjct: 71 RELKLLRHFRGHKNITCLYDMDIVFYPDGSINGLYLYEELMECDMHQIIKSGQPLTDAHY 130
Query: 121 QYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLAR------IQDPQ-MT 173
Q F YQIL GLKY+HSA V+HRDLKP N+L+N +C LKICDFGLAR +++ Q +T
Sbjct: 131 QSFTYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENSQFLT 190
Query: 174 GYVSTRYYRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLG 233
YV+TR+YRAPEIML++Q Y +D+WSAGCI AE + GKP+F GKD+V+Q + I +LG
Sbjct: 191 EYVATRWYRAPEIMLSYQGYTKAIDVWSAGCILAEFLGGKPIFKGKDYVNQLNQILQVLG 250
Query: 234 SPPKDVIDTICSENTLKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAA 293
+PP + + I S+N ++ L VPF + + N A+DLLE+ML FDP+KRIT
Sbjct: 251 TPPDETLRRIGSKNVQDYIHQLGFIPKVPFVNLYPNANSQALDLLEQMLAFDPQKRITVD 310
Query: 294 DALAHPYLSPYHDPTDEPIAEAKFDWNFNDADLPVDTWRVMMYSEILDF 342
+AL HPYLS +HDP DEP+ KF+++F + ++ + M+ E+ DF
Sbjct: 311 EALEHPYLSIWHDPADEPVCSEKFEFSFESVN-DMEDLKQMVIQEVQDF 358
>SPBC119.08 [T] KOG0660 Mitogen-activated protein kinase
Length = 422
Score = 305 bits (780), Expect = 1e-82
Identities = 156/349 (44%), Positives = 230/349 (65%), Gaps = 15/349 (4%)
Query: 10 QIFGTVFEITNRYTNLNPVGMGAFGLVCSATDTLTS--QPVAIKKIMKPFSTSVLAKRTY 67
++F + + + +G GA+G+VC+A + + + VAIKKI FS S+L KR
Sbjct: 9 RVFNQEMYVEPNFKVVKELGQGAYGIVCAARNVASKDQEAVAIKKITNVFSKSILTKRAL 68
Query: 68 RELKLLKHLR-HENLICLEDI-FLSP--LEDIYFVTELQGTDLHRLLQT-RPLEKQFVQY 122
RE+KLL H R H N+ C+ D+ ++P ++Y EL DL+ ++++ +PL Q
Sbjct: 69 REIKLLIHFRNHRNITCIYDLDIINPYNFNEVYIYEELMEADLNAIIKSGQPLTDAHFQS 128
Query: 123 FLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLAR--IQDPQ-----MTGY 175
F+YQIL GLKY+HSA VIHRDLKP N+L+N +C+LKICDFGLAR ++P+ MT Y
Sbjct: 129 FIYQILCGLKYIHSANVIHRDLKPGNLLVNADCELKICDFGLARGCSENPEENPGFMTEY 188
Query: 176 VSTRYYRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSP 235
V+TR+YRAPEIML++ Y+ +D+WS GCI AE++ G PLF GKD VHQ ++I LG+P
Sbjct: 189 VATRWYRAPEIMLSFSSYHKGIDVWSVGCILAELLGGTPLFKGKDFVHQLNLILHQLGTP 248
Query: 236 PKDVIDTICSENTLKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADA 295
++ + I S ++V SLP + P+PF + F P A+DLL K+L FDP +RI+ DA
Sbjct: 249 DEETLSHISSSRAQEYVRSLPKQRPIPFETNFPKANPLALDLLAKLLAFDPNRRISVDDA 308
Query: 296 LAHPYLSPYHDPTDEPIAEAKFDWNFNDADLPVDTWRVMMYSEILDFHQ 344
L HPYL+ +HDP+DEP+ ++ FD++F + + RV++ E+L+F Q
Sbjct: 309 LEHPYLAVWHDPSDEPVCDSVFDFSFEYIEDANELRRVIL-DEVLNFRQ 356
>At4g36450 [T] KOG0660 Mitogen-activated protein kinase
Length = 361
Score = 300 bits (768), Expect = 3e-81
Identities = 150/334 (44%), Positives = 218/334 (64%), Gaps = 5/334 (1%)
Query: 14 TVFEITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLL 73
T+FEI +Y + P+G GA+G+VCS+ ++ T++ VAIKKI F + A RT RELKLL
Sbjct: 24 TLFEIDTKYVPIKPIGRGAYGVVCSSINSETNERVAIKKIHNVFENRIDALRTLRELKLL 83
Query: 74 KHLRHENLICLEDIFLSP----LEDIYFVTELQGTDLHRLLQT-RPLEKQFVQYFLYQIL 128
+H+RHEN+I L+D+ L D+Y V EL +DL++++++ + L +YFL+Q+L
Sbjct: 84 RHVRHENVISLKDVMLPTHRYSFRDVYLVYELMDSDLNQIIKSSQSLSDDHCKYFLFQLL 143
Query: 129 RGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQMTGYVSTRYYRAPEIML 188
RGLKY+HSA ++HRDLKP N+L+N NCDLKICDFGLAR + MT YV TR+YRAPE++L
Sbjct: 144 RGLKYLHSANILHRDLKPGNLLVNANCDLKICDFGLARTYEQFMTEYVVTRWYRAPELLL 203
Query: 189 TWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENT 248
Y +D+WS GCIFAE++ KP+FPG + ++Q +I +++GS + I ++
Sbjct: 204 CCDNYGTSIDVWSVGCIFAEILGRKPIFPGTECLNQLKLIINVVGSQQDWDLQFIDNQKA 263
Query: 249 LKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPYLSPYHDPT 308
+F+ SLP FS + + P AIDLL++MLVFDP KRI+ +DAL HPY+ +P
Sbjct: 264 RRFIKSLPFSKGTHFSHIYPHANPLAIDLLQRMLVFDPTKRISVSDALLHPYMEGLLEPE 323
Query: 309 DEPIAEAKFDWNFNDADLPVDTWRVMMYSEILDF 342
P D ++ D R MM+ E+L +
Sbjct: 324 CNPSENVPVSSLEIDENMEGDMIREMMWEEMLHY 357
>YGR040w [T] KOG0660 Mitogen-activated protein kinase
Length = 368
Score = 298 bits (764), Expect = 8e-81
Identities = 162/359 (45%), Positives = 228/359 (63%), Gaps = 35/359 (9%)
Query: 16 FEITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKH 75
F+I ++Y ++ +G GA+G VCSA + VAIKKI +PFS + RT RE+KLL++
Sbjct: 7 FDIPSQYKLVDLIGEGAYGTVCSAIHKPSGIKVAIKKI-QPFSKKLFVTRTIREIKLLRY 65
Query: 76 LR-HENLICLED----IFLSPLEDIYFVTELQGTDLHRLLQTR-----PLEKQFVQYFLY 125
HEN+I + D + + L +Y V EL TDL +++ + L VQYF Y
Sbjct: 66 FHEHENIISILDKVRPVSIDKLNAVYLVEELMETDLQKVINNQNSGFSTLSDDHVQYFTY 125
Query: 126 QILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQ----------MTGY 175
QILR LK +HSA VIHRD+KPSN+L+N NCDLK+CDFGLAR MT Y
Sbjct: 126 QILRALKSIHSAQVIHRDIKPSNLLLNSNCDLKVCDFGLARCLASSSDSRETLVGFMTEY 185
Query: 176 VSTRYYRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSP 235
V+TR+YRAPEIMLT+Q+Y +DIWS GCI AEM+ GKPLFPG+D+ HQ +I ++LG+P
Sbjct: 186 VATRWYRAPEIMLTFQEYTTAMDIWSCGCILAEMVSGKPLFPGRDYHHQLWLILEVLGTP 245
Query: 236 PKDVIDTICSENTLKFVTSLPHRDPVPFSSRFQ--NLEPDAIDLLEKMLVFDPKKRITAA 293
+ + I S+ +++ +LP R P+P+ + + +L PD IDLL+KML F+P KRI+AA
Sbjct: 246 SFEDFNQIKSKRAKEYIANLPMRPPLPWETVWSKTDLNPDMIDLLDKMLQFNPDKRISAA 305
Query: 294 DALAHPYLSPYHDPTDEP-IAEAKFDWNF-----------NDADLPVDTWRVMMYSEIL 340
+AL HPYL+ YHDP+DEP D F + ++P++ + M+Y E++
Sbjct: 306 EALRHPYLAMYHDPSDEPEYPPLNLDDEFWKLDNKIMRPEEEEEVPIEMLKDMLYDELM 364
>YBL016w [T] KOG0660 Mitogen-activated protein kinase
Length = 353
Score = 297 bits (761), Expect = 2e-80
Identities = 152/318 (47%), Positives = 205/318 (63%), Gaps = 19/318 (5%)
Query: 15 VFEITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLK 74
V+ I++ + + +G GA+G+VCSAT T + VAIKKI +PF + A RT RE+K+LK
Sbjct: 6 VYNISSDFQLKSLLGEGAYGVVCSATHKPTGEIVAIKKI-EPFDKPLFALRTLREIKILK 64
Query: 75 HLRHENLICLEDI----FLSPLEDIYFVTELQGTDLHRLLQTRPLEKQFVQYFLYQILRG 130
H +HEN+I + +I ++Y + EL TDLHR++ T+ L +QYF+YQ LR
Sbjct: 65 HFKHENIITIFNIQRPDSFENFNEVYIIQELMQTDLHRVISTQMLSDDHIQYFIYQTLRA 124
Query: 131 LKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARI-------------QDPQMTGYVS 177
+K +H + VIHRDLKPSN+LIN NCDLK+CDFGLARI Q MT YV+
Sbjct: 125 VKVLHGSNVIHRDLKPSNLLINSNCDLKVCDFGLARIIDESAADNSEPTGQQSGMTEYVA 184
Query: 178 TRYYRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPK 237
TR+YRAPE+MLT KY+ +D+WS GCI AE+ +P+FPG+D+ HQ +I ++G+P
Sbjct: 185 TRWYRAPEVMLTSAKYSRAMDVWSCGCILAELFLRRPIFPGRDYRHQLLLIFGIIGTPHS 244
Query: 238 D-VIDTICSENTLKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADAL 296
D + I S +++ SLP P F + P IDLL++MLVFDP KRITA +AL
Sbjct: 245 DNDLRCIESPRAREYIKSLPMYPAAPLEKMFPRVNPKGIDLLQRMLVFDPAKRITAKEAL 304
Query: 297 AHPYLSPYHDPTDEPIAE 314
HPYL YHDP DEP E
Sbjct: 305 EHPYLQTYHDPNDEPEGE 322
>At1g18150 [T] KOG0660 Mitogen-activated protein kinase
Length = 589
Score = 297 bits (760), Expect = 2e-80
Identities = 164/348 (47%), Positives = 222/348 (63%), Gaps = 18/348 (5%)
Query: 12 FGTVFEITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELK 71
F T + NRY VG G++G+V SA D+ T + VAIKKI F A R RE+K
Sbjct: 94 FFTEYGEANRYQIQEVVGKGSYGVVASAVDSHTGERVAIKKINDVFEHVSDATRILREIK 153
Query: 72 LLKHLRHENLICLEDIFLSP----LEDIYFVTELQGTDLHRLLQTRP-LEKQFVQYFLYQ 126
LL+ LRH +++ ++ I L P DIY V EL +DLH++++ L + Q+FLYQ
Sbjct: 154 LLRLLRHPDVVEIKHIMLPPSRREFRDIYVVFELMESDLHQVIKANDDLTPEHYQFFLYQ 213
Query: 127 ILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQM------TGYVSTRY 180
+LRGLKYVH+A V HRDLKP NIL N +C LKICDFGLAR+ T YV+TR+
Sbjct: 214 LLRGLKYVHAANVFHRDLKPKNILANADCKLKICDFGLARVSFNDAPTAIFWTDYVATRW 273
Query: 181 YRAPEIMLTW-QKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDV 239
YRAPE+ ++ KY +DIWS GCIFAEM+ GKPLFPGK+ VHQ ++TD LG+PP +
Sbjct: 274 YRAPELCGSFFSKYTPAIDIWSVGCIFAEMLLGKPLFPGKNVVHQLDLMTDFLGTPPPES 333
Query: 240 IDTICSENTLKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHP 299
I I +E ++++S+ + PVPFS +F +P A+ LLE++L FDPK R +A DALA P
Sbjct: 334 ISRIRNEKARRYLSSMRKKQPVPFSHKFPKADPLALRLLERLLAFDPKDRASAEDALADP 393
Query: 300 YLS----PYHDPTDEPIAEAKFDWNFNDADLPVDTWRVMMYSEILDFH 343
Y S +PT +PI++ +FD F L D R ++Y EIL++H
Sbjct: 394 YFSGLSNSEREPTTQPISKLEFD--FERKKLVKDDVRELIYREILEYH 439
>Hs20986514 [T] KOG0660 Mitogen-activated protein kinase
Length = 297
Score = 294 bits (753), Expect = 2e-79
Identities = 142/279 (50%), Positives = 193/279 (68%), Gaps = 7/279 (2%)
Query: 1 MSNEE--FIRTQIFGTVFEITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFS 58
MS E F R ++ T++E+ RY NL+PVG GA+G VC+A DT T VA+KK+ +PF
Sbjct: 1 MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQ 60
Query: 59 TSVLAKRTYRELKLLKHLRHENLICLEDIF-----LSPLEDIYFVTELQGTDLHRLLQTR 113
+ + AKRTYREL+LLKH++HEN+I L D+F L D+Y VT L G DL+ +++ +
Sbjct: 61 SIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ 120
Query: 114 PLEKQFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQMT 173
L VQ+ +YQILRGLKY+HSA +IHRDLKPSN+ +NE+C+LKI DFGLAR D +MT
Sbjct: 121 KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMT 180
Query: 174 GYVSTRYYRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLG 233
GYV+TR+YRAPEIML W YN VDIWS GCI AE++ G+ LFPG DH+ Q +I L+G
Sbjct: 181 GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVG 240
Query: 234 SPPKDVIDTICSENTLKFVTSLPHRDPVPFSSRFQNLEP 272
+P +++ I SE+ ++ SL + F++ F P
Sbjct: 241 TPGAELLKKISSESARNYIQSLTQMPKMNFANVFIGANP 279
>At3g14720 [T] KOG0660 Mitogen-activated protein kinase
Length = 586
Score = 291 bits (746), Expect = 1e-78
Identities = 159/348 (45%), Positives = 223/348 (63%), Gaps = 18/348 (5%)
Query: 12 FGTVFEITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELK 71
F T + NRY L +G G++G+VC+A DT T + VAIKKI F A R RE+K
Sbjct: 3 FFTEYGDANRYRILEVIGKGSYGVVCAAIDTQTGEKVAIKKINDVFEHVSDALRILREVK 62
Query: 72 LLKHLRHENLICLEDIFLSP----LEDIYFVTELQGTDLHRLLQTRP-LEKQFVQYFLYQ 126
LL+ LRH +++ ++ I L P +DIY V EL +DLH++++ L ++ Q+FLYQ
Sbjct: 63 LLRLLRHPDIVEIKSIMLPPSKREFKDIYVVFELMESDLHQVIKANDDLTREHHQFFLYQ 122
Query: 127 ILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQM------TGYVSTRY 180
+LR LKY+H+A V HRDLKP NIL N NC LK+CDFGLAR+ T YV+TR+
Sbjct: 123 MLRALKYMHTANVYHRDLKPKNILANANCKLKVCDFGLARVSFNDTPTTVFWTDYVATRW 182
Query: 181 YRAPEIMLTW-QKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDV 239
YRAPE+ ++ KY +DIWS GCIFAE++ GKPLFPGK VHQ +ITDLLG+P +
Sbjct: 183 YRAPELCGSFCSKYTPAIDIWSIGCIFAEVLTGKPLFPGKSVVHQLDLITDLLGTPKSET 242
Query: 240 IDTICSENTLKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHP 299
I + +E K++ + ++ VPFS +F N +P A+ LL+++L FDPK R TAA+ALA P
Sbjct: 243 IAGVRNEKARKYLNEMRKKNLVPFSQKFPNADPLALRLLQRLLAFDPKDRPTAAEALADP 302
Query: 300 YL----SPYHDPTDEPIAEAKFDWNFNDADLPVDTWRVMMYSEILDFH 343
Y +P+ +PI++ +F+ F L D R ++Y EIL++H
Sbjct: 303 YFKCLAKVEREPSCQPISKMEFE--FERRRLTKDDIRELIYREILEYH 348
>At2g42880 [T] KOG0660 Mitogen-activated protein kinase
Length = 594
Score = 289 bits (740), Expect = 5e-78
Identities = 154/340 (45%), Positives = 220/340 (64%), Gaps = 18/340 (5%)
Query: 20 NRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHE 79
NR+ +G G++G+VCSA DTLT + VAIKKI F A R RE+KLL+ LRH
Sbjct: 11 NRFKVQEVIGKGSYGVVCSAIDTLTGEKVAIKKIHDIFEHISDAARILREIKLLRLLRHP 70
Query: 80 NLICLEDIFLSP----LEDIYFVTELQGTDLHRLLQTRP-LEKQFVQYFLYQILRGLKYV 134
+++ ++ I L P +DIY V EL +DLH++++ L ++ Q+FLYQ+LR LKY+
Sbjct: 71 DIVEIKHIMLPPSRREFKDIYVVFELMESDLHQVIKANDDLTREHYQFFLYQLLRALKYI 130
Query: 135 HSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQM------TGYVSTRYYRAPEIML 188
H+A V HRDLKP NIL N NC LKICDFGLAR+ T YV+TR+YRAPE+
Sbjct: 131 HTANVYHRDLKPKNILANANCKLKICDFGLARVAFNDTPTTIFWTDYVATRWYRAPELCG 190
Query: 189 T-WQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSEN 247
+ + KY +DIWS GCIFAE++ GKPLFPGK+ VHQ ++TDLLG+P D I + +E
Sbjct: 191 SFYSKYTPAIDIWSIGCIFAEVLMGKPLFPGKNVVHQLDLMTDLLGTPSLDTISRVRNEK 250
Query: 248 TLKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPYLSPY--- 304
+++TS+ + P+PF+ +F N +P ++ LLE++L FDPK R TA +ALA PY
Sbjct: 251 ARRYLTSMRKKPPIPFAQKFPNADPLSLKLLERLLAFDPKDRPTAEEALADPYFKGLAKV 310
Query: 305 -HDPTDEPIAEAKFDWNFNDADLPVDTWRVMMYSEILDFH 343
+P+ +PI + +F+ F + + R ++ EIL++H
Sbjct: 311 EREPSCQPITKMEFE--FERRKVTKEDIRELISREILEYH 348
>At1g73670 [T] KOG0660 Mitogen-activated protein kinase
Length = 576
Score = 288 bits (736), Expect = 1e-77
Identities = 158/348 (45%), Positives = 220/348 (62%), Gaps = 18/348 (5%)
Query: 12 FGTVFEITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELK 71
F T + NRY VG G++G+V SA DT T + VAIKKI F A R RE+K
Sbjct: 80 FFTEYGEANRYQIQEVVGKGSYGVVGSAIDTHTGERVAIKKINDVFDHISDATRILREIK 139
Query: 72 LLKHLRHENLICLEDIFLSP----LEDIYFVTELQGTDLHRLLQTRP-LEKQFVQYFLYQ 126
LL+ L H +++ ++ I L P D+Y V EL +DLH++++ L + Q+FLYQ
Sbjct: 140 LLRLLLHPDVVEIKHIMLPPSRREFRDVYVVFELMESDLHQVIKANDDLTPEHHQFFLYQ 199
Query: 127 ILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQM------TGYVSTRY 180
+LRGLKYVH+A V HRDLKP NIL N +C LKICDFGLAR+ T YV+TR+
Sbjct: 200 LLRGLKYVHAANVFHRDLKPKNILANADCKLKICDFGLARVSFNDAPTAIFWTDYVATRW 259
Query: 181 YRAPEIMLTW-QKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDV 239
YRAPE+ ++ KY +DIWS GCIFAEM+ GKPLFPGK+ VHQ I+TD LG+PP +
Sbjct: 260 YRAPELCGSFFSKYTPAIDIWSVGCIFAEMLLGKPLFPGKNVVHQLDIMTDFLGTPPPEA 319
Query: 240 IDTICSENTLKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHP 299
I I ++ +++ ++ + PVPFS +F +P A+ LLE+++ FDPK R +A +ALA P
Sbjct: 320 ISKIRNDKARRYLGNMRKKQPVPFSKKFPKADPSALRLLERLIAFDPKDRPSAEEALADP 379
Query: 300 YL----SPYHDPTDEPIAEAKFDWNFNDADLPVDTWRVMMYSEILDFH 343
Y S +P+ +PI++ +F+ F L D R ++Y EIL++H
Sbjct: 380 YFNGLSSKVREPSTQPISKLEFE--FERKKLTKDDIRELIYREILEYH 425
>At1g53510 [T] KOG0660 Mitogen-activated protein kinase
Length = 603
Score = 287 bits (735), Expect = 2e-77
Identities = 154/346 (44%), Positives = 219/346 (62%), Gaps = 14/346 (4%)
Query: 12 FGTVFEITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELK 71
F T + NRY L +G G++G+VC+A DT T + VAIKKI F A R RE+K
Sbjct: 3 FFTEYGDANRYRILEVIGKGSYGVVCAAIDTHTGEKVAIKKINDVFEHISDALRILREVK 62
Query: 72 LLKHLRHENLICLEDIFLSP----LEDIYFVTELQGTDLHRLLQTRP-LEKQFVQYFLYQ 126
LL+ LRH +++ ++ I L P +DIY V EL +DLH++++ L ++ Q+FLYQ
Sbjct: 63 LLRLLRHPDIVEIKSIMLPPSKREFKDIYVVFELMESDLHQVIKANDDLTREHHQFFLYQ 122
Query: 127 ILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQM------TGYVSTRY 180
+LR LK++H+A V HRDLKP NIL N NC LK+CDFGLAR+ T YV+TR+
Sbjct: 123 MLRALKFMHTANVYHRDLKPKNILANANCKLKVCDFGLARVAFNDTPTTVFWTDYVATRW 182
Query: 181 YRAPEIMLTW-QKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDV 239
YRAPE+ ++ KY +D+WS GCIFAE++ GKPLFPGK VHQ +ITDLLG+P +
Sbjct: 183 YRAPELCGSFFSKYTPAIDVWSIGCIFAEVLTGKPLFPGKSVVHQLELITDLLGTPKSET 242
Query: 240 IDTICSENTLKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHP 299
I + ++ K++T + ++PV FS +F +P A+ LL+++L FDPK R T A+ALA P
Sbjct: 243 ISGVRNDKARKYLTEMRKKNPVTFSQKFSKADPLALRLLQRLLAFDPKDRPTPAEALADP 302
Query: 300 YLSPYHDPTDEPIAE--AKFDWNFNDADLPVDTWRVMMYSEILDFH 343
Y EP ++ +K ++ F L D R ++Y EIL++H
Sbjct: 303 YFKGLSKIEREPSSQQISKMEFEFERRRLTKDDIRELIYREILEYH 348
>Hs20986516 [T] KOG0660 Mitogen-activated protein kinase
Length = 307
Score = 286 bits (733), Expect = 3e-77
Identities = 137/254 (53%), Positives = 183/254 (71%), Gaps = 7/254 (2%)
Query: 1 MSNEE--FIRTQIFGTVFEITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFS 58
MS E F R ++ T++E+ RY NL+PVG GA+G VC+A DT T VA+KK+ +PF
Sbjct: 1 MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQ 60
Query: 59 TSVLAKRTYRELKLLKHLRHENLICLEDIF-----LSPLEDIYFVTELQGTDLHRLLQTR 113
+ + AKRTYREL+LLKH++HEN+I L D+F L D+Y VT L G DL+ +++ +
Sbjct: 61 SIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ 120
Query: 114 PLEKQFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQMT 173
L VQ+ +YQILRGLKY+HSA +IHRDLKPSN+ +NE+C+LKI DFGLAR D +MT
Sbjct: 121 KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMT 180
Query: 174 GYVSTRYYRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLG 233
GYV+TR+YRAPEIML W YN VDIWS GCI AE++ G+ LFPG DH+ Q +I L+G
Sbjct: 181 GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVG 240
Query: 234 SPPKDVIDTICSEN 247
+P +++ I SE+
Sbjct: 241 TPGAELLKKISSES 254
>At3g18040 [T] KOG0660 Mitogen-activated protein kinase
Length = 613
Score = 281 bits (720), Expect = 1e-75
Identities = 152/348 (43%), Positives = 222/348 (63%), Gaps = 18/348 (5%)
Query: 12 FGTVFEITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELK 71
F T + +RY +G G++G+V SA DT + + VAIKKI F A R RE+K
Sbjct: 116 FFTEYGEASRYQIQEVIGKGSYGVVASAIDTHSGEKVAIKKINDVFEHVSDATRILREIK 175
Query: 72 LLKHLRHENLICLEDIFLSP----LEDIYFVTELQGTDLHRLLQTRP-LEKQFVQYFLYQ 126
LL+ LRH +++ ++ + L P DIY V EL +DLH++++ L + Q+FLYQ
Sbjct: 176 LLRLLRHPDIVEIKHVMLPPSRREFRDIYVVFELMESDLHQVIKANDDLTPEHYQFFLYQ 235
Query: 127 ILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQM------TGYVSTRY 180
+LRGLK++H+A V HRDLKP NIL N +C LKICDFGLAR+ T YV+TR+
Sbjct: 236 LLRGLKFIHTANVFHRDLKPKNILANSDCKLKICDFGLARVSFNDAPSAIFWTDYVATRW 295
Query: 181 YRAPEIMLTW-QKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDV 239
YRAPE+ ++ KY +DIWS GCIFAEM+ GKPLFPGK+ VHQ I+TDLLG+PP +
Sbjct: 296 YRAPELCGSFFSKYTPAIDIWSIGCIFAEMLTGKPLFPGKNVVHQLDIMTDLLGTPPPEA 355
Query: 240 IDTICSENTLKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHP 299
I I +E +++ ++ + PVPF+ +F +++P A+ LL ++L FDPK R +A +ALA P
Sbjct: 356 IARIRNEKARRYLGNMRRKPPVPFTHKFPHVDPLALRLLHRLLAFDPKDRPSAEEALADP 415
Query: 300 YL----SPYHDPTDEPIAEAKFDWNFNDADLPVDTWRVMMYSEILDFH 343
Y + +P+ +PI + +F+ F + + R ++Y EIL++H
Sbjct: 416 YFYGLANVDREPSTQPIPKLEFE--FERRKITKEDVRELIYREILEYH 461
>At5g19010 [T] KOG0660 Mitogen-activated protein kinase
Length = 567
Score = 280 bits (716), Expect = 3e-75
Identities = 153/346 (44%), Positives = 217/346 (62%), Gaps = 14/346 (4%)
Query: 12 FGTVFEITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELK 71
F T + +RY +G G++G+VCSA DT T + VAIKKI F A R RE+K
Sbjct: 15 FFTEYGEGSRYRIEEVIGKGSYGVVCSAYDTHTGEKVAIKKINDIFEHVSDATRILREIK 74
Query: 72 LLKHLRHENLICLEDIFLSP----LEDIYFVTELQGTDLHRLLQTRP-LEKQFVQYFLYQ 126
LL+ LRH +++ ++ I L P DIY V EL +DLH++++ L + Q+FLYQ
Sbjct: 75 LLRLLRHPDIVEIKHILLPPSRREFRDIYVVFELMESDLHQVIKANDDLTPEHYQFFLYQ 134
Query: 127 ILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQM------TGYVSTRY 180
+LRGLKY+H+A V HRDLKP NIL N +C LKICDFGLAR+ T YV+TR+
Sbjct: 135 LLRGLKYIHTANVFHRDLKPKNILANADCKLKICDFGLARVAFNDTPTAIFWTDYVATRW 194
Query: 181 YRAPEIMLTW-QKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDV 239
YRAPE+ ++ KY +DIWS GCIFAE++ GKPLFPGK+ VHQ ++TD+LG+P +
Sbjct: 195 YRAPELCGSFFSKYTPAIDIWSIGCIFAELLTGKPLFPGKNVVHQLDLMTDMLGTPSAEA 254
Query: 240 IDTICSENTLKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHP 299
I + +E ++++S+ + P+PFS +F + +P A+ LLEKML F+PK R TA +ALA
Sbjct: 255 IGRVRNEKARRYLSSMRKKKPIPFSHKFPHTDPLALRLLEKMLSFEPKDRPTAEEALADV 314
Query: 300 YLSPYHDPTDEPIAE--AKFDWNFNDADLPVDTWRVMMYSEILDFH 343
Y EP A+ K ++ F + + R ++Y E L++H
Sbjct: 315 YFKGLAKVEREPSAQPVTKLEFEFERRRITKEDVRELIYRESLEYH 360
>CE17062 [T] KOG0660 Mitogen-activated protein kinase
Length = 448
Score = 280 bits (715), Expect = 4e-75
Identities = 149/364 (40%), Positives = 213/364 (57%), Gaps = 57/364 (15%)
Query: 4 EEFIRTQIFGTVFEITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLA 63
E + ++ T + + Y +L P+G GA+G+VC+A T VAIKK +PF +++ A
Sbjct: 31 EGYHEVELNKTKWVLPQWYNSLKPLGEGAYGVVCTAEYEPTGDRVAIKKFFRPFQSTIHA 90
Query: 64 KRTYRELKLLKHLRHENLICLEDIFL-----SPLEDIYFVTELQGTDLHRLLQTRPLEKQ 118
KRTYRELKLL+ L+H+N++ + D+F S L ++YFV+ L G+DL +++ + L +
Sbjct: 91 KRTYRELKLLRTLQHDNVLEMIDVFTPDPDASSLNNVYFVSVLMGSDLQNIMKIQRLTDE 150
Query: 119 FVQYFLYQILRGLKY-----------------------------VHSAGVIHRDLKPSNI 149
+Q +YQ+LRGLKY +HSAG+IHRDLKPSNI
Sbjct: 151 QIQLLIYQVLRGLKYMSHQNFNSTIILKKLMHPFQRRNTRFRLYIHSAGIIHRDLKPSNI 210
Query: 150 LINENCDLK-----------------ICDFGLARIQDPQMTGYVSTRYYRAPEIMLTWQK 192
+NE C++K I DFGLAR QD +MTGYV+TR+YRAPEIML W
Sbjct: 211 AVNERCEVKVFLSFSQLSFLILSFFKILDFGLARAQDAEMTGYVATRWYRAPEIMLNWMH 270
Query: 193 YNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLKFV 252
Y VD+WS GCI AE++ G+PLFPG DH+ Q + I ++G+P ++ I SE ++
Sbjct: 271 YTQTVDVWSVGCILAELVSGRPLFPGDDHIDQLTKIMSVVGTPKEEFWSKIQSEEARNYI 330
Query: 253 TSLPHRDPV---PFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPYLSPYHDPTD 309
+R P+ F + F P A++LLE ML+ DP +RI+ + AL H YL Y P D
Sbjct: 331 ---KNRSPIIRQDFVTLFPMASPYALELLEMMLILDPDRRISVSSALRHDYLREYSVPND 387
Query: 310 EPIA 313
EP+A
Sbjct: 388 EPVA 391
>CE06762 [T] KOG0660 Mitogen-activated protein kinase
Length = 367
Score = 271 bits (693), Expect = 1e-72
Identities = 141/301 (46%), Positives = 201/301 (65%), Gaps = 16/301 (5%)
Query: 28 VGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHENLICLEDI 87
VG GA+G+VC A DT + VAIKKI + F+ LAKR+ RE+++L+ L HEN+I + D+
Sbjct: 63 VGAGAYGVVCKAMDTRNKKQVAIKKIPRAFTAHTLAKRSLREVRILRELLHENIIAVLDM 122
Query: 88 FLSPL---EDIYFVTELQGTDLHRLLQTRP-LEKQFVQYFLYQILRGLKYVHSAGVIHRD 143
F + +DIY V +L TDLH++L +R L +Q QYF YQ+LRGLKY+HSAG+IHRD
Sbjct: 123 FTAEGAHGKDIYLVMDLMETDLHQILHSRQTLMEQHFQYFFYQLLRGLKYLHSAGIIHRD 182
Query: 144 LKPSNILINENCDLKICDFGLAR-------IQDP-----QMTGYVSTRYYRAPEIMLTWQ 191
LKPSN+L+N +C L+I DFG+AR ++D MT YVSTR+YRAPEI+ +
Sbjct: 183 LKPSNLLLNGDCLLRIADFGMARAYASASTVRDDANVGGHMTQYVSTRWYRAPEILFSMV 242
Query: 192 KYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLKF 251
+Y+ +VD+WSAGCIFAEM+ + LFPGKD V Q +I LGSP ++VI+ I S+
Sbjct: 243 EYDTKVDLWSAGCIFAEMLLRRQLFPGKDSVSQIKMIVYYLGSPEEEVINRITSDLVRDS 302
Query: 252 VTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPYLSPYHDPTDEP 311
+ + + P+PFS+ F P+A +++ +L P KR +A L HP+++ YH+ EP
Sbjct: 303 IEACGRKTPLPFSAIFPKASPEARNMVSYLLQISPWKRYSADQILQHPFMAQYHNDQYEP 362
Query: 312 I 312
+
Sbjct: 363 L 363
>At2g01450 [T] KOG0660 Mitogen-activated protein kinase
Length = 516
Score = 268 bits (685), Expect = 1e-71
Identities = 149/343 (43%), Positives = 213/343 (61%), Gaps = 18/343 (5%)
Query: 12 FGTVFEITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELK 71
F T + ++Y VG G++G+V SA T VAIKK+ F A R RE+K
Sbjct: 6 FFTEYGEASQYQIQEVVGKGSYGVVASAECPHTGGKVAIKKMTNVFEHVSDAIRILREIK 65
Query: 72 LLKHLRHENLICLEDIFLSP----LEDIYFVTELQGTDLHRLLQTRP-LEKQFVQYFLYQ 126
LL+ LRH +++ ++ I L P +DIY V EL +DLH +L+ L Q Q+FLYQ
Sbjct: 66 LLRLLRHPDIVEIKHIMLPPCRKEFKDIYVVFELMESDLHHVLKVNDDLTPQHHQFFLYQ 125
Query: 127 ILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQM------TGYVSTRY 180
+LRGLK++HSA V HRDLKP NIL N +C +KICD GLAR+ T YV+TR+
Sbjct: 126 LLRGLKFMHSAHVFHRDLKPKNILANADCKIKICDLGLARVSFTDSPSAVFWTDYVATRW 185
Query: 181 YRAPEIMLT-WQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDV 239
YRAPE+ + + Y +D+WS GCIFAEM+ GKPLFPGK+ VHQ ++TDLLG+P
Sbjct: 186 YRAPELCGSFYSNYTPAIDMWSVGCIFAEMLTGKPLFPGKNVVHQLELVTDLLGTPSPIT 245
Query: 240 IDTICSENTLKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHP 299
+ I +E K++ ++ +DPVPF+ +F N++P A+ LL++++ FDPK R +A +ALA P
Sbjct: 246 LSRIRNEKARKYLGNMRRKDPVPFTHKFPNIDPVALKLLQRLIAFDPKDRPSAEEALADP 305
Query: 300 YLSPY----HDPTDEPIAEAKFDWNFNDADLPVDTWRVMMYSE 338
Y ++P+ +PI++ +F+ F L D R +MY E
Sbjct: 306 YFQGLANVDYEPSRQPISKLEFE--FERRKLTRDDVRELMYRE 346
>Hs21237745 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 424
Score = 262 bits (670), Expect = 7e-70
Identities = 148/383 (38%), Positives = 221/383 (57%), Gaps = 33/383 (8%)
Query: 3 NEEFIRTQIFGTVFEITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVL 62
+ +F Q+ + F + RY L P+G GA G+VC+A DT+ VA+KK+ +PF
Sbjct: 7 DSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTH 66
Query: 63 AKRTYRELKLLKHLRHENLICLEDIF-----LSPLEDIYFVTELQGTDLHRLLQTRPLEK 117
AKR YREL LLK + H+N+I L ++F L +D+Y V EL +L +++ L+
Sbjct: 67 AKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIHME-LDH 125
Query: 118 QFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLAR--IQDPQMTGY 175
+ + Y LYQ+L G+K++HSAG+IHRDLKPSNI++ +C LKI DFGLAR + MT Y
Sbjct: 126 ERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNFMMTPY 185
Query: 176 VSTRYYRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSP 235
V TRYYRAPE++L Y VDIWS GCI AEM+ K LFPG+D++ Q++ + + LG+P
Sbjct: 186 VVTRYYRAPEVIL-GMGYKENVDIWSVGCIMAEMVLHKVLFPGRDYIDQWNKVIEQLGTP 244
Query: 236 PKDVIDTICSENTLKFVTSLPHRDPVPFSSRF------QNLEPDAI------DLLEKMLV 283
+ + + +V + P + F F E D I DLL KMLV
Sbjct: 245 SAEFMKKL-QPTVRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSKMLV 303
Query: 284 FDPKKRITAADALAHPYLSPYHDPTD-EPIAEAKFDWNFNDADLPVDTWRVMMYSEILDF 342
DP KRI+ +AL HPY++ ++DP + E +D + + ++ W+ ++Y E++D+
Sbjct: 304 IDPDKRISVDEALRHPYITVWYDPAEAEAPPPQIYDAQLEEREHAIEEWKELIYKEVMDW 363
Query: 343 H----------QIGDPQINTNAT 355
Q D +++NAT
Sbjct: 364 EERSKNGVVKDQPSDAAVSSNAT 386
>Hs21237742 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 382
Score = 261 bits (667), Expect = 1e-69
Identities = 143/362 (39%), Positives = 214/362 (58%), Gaps = 23/362 (6%)
Query: 3 NEEFIRTQIFGTVFEITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVL 62
+ +F Q+ + F + RY L P+G GA G+VC+A DT+ VA+KK+ +PF
Sbjct: 7 DSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTH 66
Query: 63 AKRTYRELKLLKHLRHENLICLEDIF-----LSPLEDIYFVTELQGTDLHRLLQTRPLEK 117
AKR YREL LLK + H+N+I L ++F L +D+Y V EL +L +++ L+
Sbjct: 67 AKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIHME-LDH 125
Query: 118 QFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLAR--IQDPQMTGY 175
+ + Y LYQ+L G+K++HSAG+IHRDLKPSNI++ +C LKI DFGLAR + MT Y
Sbjct: 126 ERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNFMMTPY 185
Query: 176 VSTRYYRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSP 235
V TRYYRAPE++L Y VDIWS GCI AEM+ K LFPG+D++ Q++ + + LG+P
Sbjct: 186 VVTRYYRAPEVIL-GMGYKENVDIWSVGCIMAEMVLHKVLFPGRDYIDQWNKVIEQLGTP 244
Query: 236 PKDVIDTICSENTLKFVTSLPHRDPVPFSSRF------QNLEPDAI------DLLEKMLV 283
+ + + +V + P + F F E D I DLL KMLV
Sbjct: 245 SAEFMKKL-QPTVRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSKMLV 303
Query: 284 FDPKKRITAADALAHPYLSPYHDPTD-EPIAEAKFDWNFNDADLPVDTWRVMMYSEILDF 342
DP KRI+ +AL HPY++ ++DP + E +D + + ++ W+ ++Y E++D+
Sbjct: 304 IDPDKRISVDEALRHPYITVWYDPAEAEAPPPQIYDAQLEEREHAIEEWKELIYKEVMDW 363
Query: 343 HQ 344
+
Sbjct: 364 EE 365
>Hs20986521 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 427
Score = 260 bits (664), Expect = 3e-69
Identities = 142/362 (39%), Positives = 211/362 (58%), Gaps = 23/362 (6%)
Query: 3 NEEFIRTQIFGTVFEITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVL 62
+ F +I + F + RY NL P+G GA G+VC+A D + + VAIKK+ +PF
Sbjct: 7 DNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTH 66
Query: 63 AKRTYRELKLLKHLRHENLICLEDIF-----LSPLEDIYFVTELQGTDLHRLLQTRPLEK 117
AKR YREL L+K + H+N+I L ++F L +D+Y V EL +L +++Q L+
Sbjct: 67 AKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQME-LDH 125
Query: 118 QFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDP--QMTGY 175
+ + Y LYQ+L G+K++HSAG+IHRDLKPSNI++ +C LKI DFGLAR MT Y
Sbjct: 126 ERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPY 185
Query: 176 VSTRYYRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSP 235
V TRYYRAPE++L Y VDIWS GCI EMI+G LFPG DH+ Q++ + + LG+P
Sbjct: 186 VVTRYYRAPEVIL-GMGYKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQLGTP 244
Query: 236 PKDVIDTICSENTLKFVTSLPHRDPVPFSSRFQNL------------EPDAIDLLEKMLV 283
+ + + +V + P F F ++ A DLL KMLV
Sbjct: 245 CPEFMKKL-QPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSKMLV 303
Query: 284 FDPKKRITAADALAHPYLSPYHDPTDEPIAEAKF-DWNFNDADLPVDTWRVMMYSEILDF 342
D KRI+ +AL HPY++ ++DP++ K D ++ + ++ W+ ++Y E++D
Sbjct: 304 IDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEVMDL 363
Query: 343 HQ 344
+
Sbjct: 364 EE 365
>Hs20986519 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 384
Score = 260 bits (664), Expect = 3e-69
Identities = 142/362 (39%), Positives = 211/362 (58%), Gaps = 23/362 (6%)
Query: 3 NEEFIRTQIFGTVFEITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVL 62
+ F +I + F + RY NL P+G GA G+VC+A D + + VAIKK+ +PF
Sbjct: 7 DNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTH 66
Query: 63 AKRTYRELKLLKHLRHENLICLEDIF-----LSPLEDIYFVTELQGTDLHRLLQTRPLEK 117
AKR YREL L+K + H+N+I L ++F L +D+Y V EL +L +++Q L+
Sbjct: 67 AKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQME-LDH 125
Query: 118 QFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDP--QMTGY 175
+ + Y LYQ+L G+K++HSAG+IHRDLKPSNI++ +C LKI DFGLAR MT Y
Sbjct: 126 ERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPY 185
Query: 176 VSTRYYRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSP 235
V TRYYRAPE++L Y VDIWS GCI EMI+G LFPG DH+ Q++ + + LG+P
Sbjct: 186 VVTRYYRAPEVIL-GMGYKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQLGTP 244
Query: 236 PKDVIDTICSENTLKFVTSLPHRDPVPFSSRFQNL------------EPDAIDLLEKMLV 283
+ + + +V + P F F ++ A DLL KMLV
Sbjct: 245 CPEFMKKL-QPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSKMLV 303
Query: 284 FDPKKRITAADALAHPYLSPYHDPTDEPIAEAKF-DWNFNDADLPVDTWRVMMYSEILDF 342
D KRI+ +AL HPY++ ++DP++ K D ++ + ++ W+ ++Y E++D
Sbjct: 304 IDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEVMDL 363
Query: 343 HQ 344
+
Sbjct: 364 EE 365
>Hs4506081 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 422
Score = 259 bits (663), Expect = 4e-69
Identities = 144/358 (40%), Positives = 215/358 (59%), Gaps = 21/358 (5%)
Query: 3 NEEFIRTQIFGTVFEITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVL 62
+ +F ++ + F + RY NL P+G GA G+VC+A D + + VAIKK+ +PF
Sbjct: 45 DNQFYSVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTH 104
Query: 63 AKRTYRELKLLKHLRHENLICLEDIF-----LSPLEDIYFVTELQGTDLHRLLQTRPLEK 117
AKR YREL L+K + H+N+I L ++F L +D+Y V EL +L +++Q L+
Sbjct: 105 AKRAYRELVLMKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQME-LDH 163
Query: 118 QFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDP--QMTGY 175
+ + Y LYQ+L G+K++HSAG+IHRDLKPSNI++ +C LKI DFGLAR MT Y
Sbjct: 164 ERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPY 223
Query: 176 VSTRYYRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSP 235
V TRYYRAPE++L Y VDIWS GCI EM+ K LFPG+D++ Q++ + + LG+P
Sbjct: 224 VVTRYYRAPEVIL-GMGYKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTP 282
Query: 236 PKDVIDTI------CSENTLKFV-TSLPHRDP---VPFSSRFQNLE-PDAIDLLEKMLVF 284
+ + + EN K+ + P P P S L+ A DLL KMLV
Sbjct: 283 CPEFMKKLQPTVRNYVENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVI 342
Query: 285 DPKKRITAADALAHPYLSPYHDPTD-EPIAEAKFDWNFNDADLPVDTWRVMMYSEILD 341
DP KRI+ DAL HPY++ ++DP + E +D ++ + ++ W+ ++Y E+++
Sbjct: 343 DPAKRISVDDALQHPYINVWYDPAEVEAPPPQIYDKQLDEREHTIEEWKELIYKEVMN 400
>Hs20986510 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 464
Score = 259 bits (663), Expect = 4e-69
Identities = 144/358 (40%), Positives = 215/358 (59%), Gaps = 21/358 (5%)
Query: 3 NEEFIRTQIFGTVFEITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVL 62
+ +F ++ + F + RY NL P+G GA G+VC+A D + + VAIKK+ +PF
Sbjct: 45 DNQFYSVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTH 104
Query: 63 AKRTYRELKLLKHLRHENLICLEDIF-----LSPLEDIYFVTELQGTDLHRLLQTRPLEK 117
AKR YREL L+K + H+N+I L ++F L +D+Y V EL +L +++Q L+
Sbjct: 105 AKRAYRELVLMKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQME-LDH 163
Query: 118 QFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDP--QMTGY 175
+ + Y LYQ+L G+K++HSAG+IHRDLKPSNI++ +C LKI DFGLAR MT Y
Sbjct: 164 ERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPY 223
Query: 176 VSTRYYRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSP 235
V TRYYRAPE++L Y VDIWS GCI EM+ K LFPG+D++ Q++ + + LG+P
Sbjct: 224 VVTRYYRAPEVIL-GMGYKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTP 282
Query: 236 PKDVIDTI------CSENTLKFV-TSLPHRDP---VPFSSRFQNLE-PDAIDLLEKMLVF 284
+ + + EN K+ + P P P S L+ A DLL KMLV
Sbjct: 283 CPEFMKKLQPTVRNYVENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVI 342
Query: 285 DPKKRITAADALAHPYLSPYHDPTD-EPIAEAKFDWNFNDADLPVDTWRVMMYSEILD 341
DP KRI+ DAL HPY++ ++DP + E +D ++ + ++ W+ ++Y E+++
Sbjct: 343 DPAKRISVDDALQHPYINVWYDPAEVEAPPPQIYDKQLDEREHTIEEWKELIYKEVMN 400
>Hs20986506 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 426
Score = 259 bits (663), Expect = 4e-69
Identities = 144/358 (40%), Positives = 215/358 (59%), Gaps = 21/358 (5%)
Query: 3 NEEFIRTQIFGTVFEITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVL 62
+ +F ++ + F + RY NL P+G GA G+VC+A D + + VAIKK+ +PF
Sbjct: 7 DNQFYSVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTH 66
Query: 63 AKRTYRELKLLKHLRHENLICLEDIF-----LSPLEDIYFVTELQGTDLHRLLQTRPLEK 117
AKR YREL L+K + H+N+I L ++F L +D+Y V EL +L +++Q L+
Sbjct: 67 AKRAYRELVLMKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQME-LDH 125
Query: 118 QFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDP--QMTGY 175
+ + Y LYQ+L G+K++HSAG+IHRDLKPSNI++ +C LKI DFGLAR MT Y
Sbjct: 126 ERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPY 185
Query: 176 VSTRYYRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSP 235
V TRYYRAPE++L Y VDIWS GCI EM+ K LFPG+D++ Q++ + + LG+P
Sbjct: 186 VVTRYYRAPEVIL-GMGYKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTP 244
Query: 236 PKDVIDTI------CSENTLKFV-TSLPHRDP---VPFSSRFQNLE-PDAIDLLEKMLVF 284
+ + + EN K+ + P P P S L+ A DLL KMLV
Sbjct: 245 CPEFMKKLQPTVRNYVENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVI 304
Query: 285 DPKKRITAADALAHPYLSPYHDPTD-EPIAEAKFDWNFNDADLPVDTWRVMMYSEILD 341
DP KRI+ DAL HPY++ ++DP + E +D ++ + ++ W+ ++Y E+++
Sbjct: 305 DPAKRISVDDALQHPYINVWYDPAEVEAPPPQIYDKQLDEREHTIEEWKELIYKEVMN 362
>7297631 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 372
Score = 259 bits (663), Expect = 4e-69
Identities = 147/355 (41%), Positives = 210/355 (58%), Gaps = 26/355 (7%)
Query: 10 QIFGTVFEITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRE 69
++ T F I +RY NL P+G GA G+VC+A DT+T Q VAIKK+ +PF AKR YRE
Sbjct: 12 EVGDTNFTIHSRYINLRPIGSGAQGIVCAAYDTITQQNVAIKKLSRPFQNVTHAKRAYRE 71
Query: 70 LKLLKHLRHENLICLEDIF-----LSPLEDIYFVTELQGTDLHRLLQTRPLEKQFVQYFL 124
KL+K + H+N+I L + F L +D+Y V EL +L +++Q L+ + Y L
Sbjct: 72 FKLMKLVNHKNIIGLLNAFTPQRNLEEFQDVYLVMELMDANLCQVIQ-MDLDHDRMSYLL 130
Query: 125 YQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDP--QMTGYVSTRYYR 182
YQ+L G+K++HSAG+IHRDLKPSNI++ +C LKI DFGLAR MT YV TRYYR
Sbjct: 131 YQMLCGIKHLHSAGIIHRDLKPSNIVVKADCTLKILDFGLARTAGTTFMMTPYVVTRYYR 190
Query: 183 APEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDT 242
APE++L Y VDIWS GCI EMI G LFPG DH+ Q++ I + LG+P +
Sbjct: 191 APEVIL-GMGYTENVDIWSVGCIMGEMIRGGVLFPGTDHIDQWNKIIEQLGTPSPSFMQR 249
Query: 243 ICSENTLKFVTSLPHRDPVPFSSRF-------------QNLEPDAIDLLEKMLVFDPKKR 289
+ +V + P F F + DA +LL KMLV DP++R
Sbjct: 250 L-QPTVRNYVENRPRYTGYSFDRLFPDGLFPNDNNQNSRRKASDARNLLSKMLVIDPEQR 308
Query: 290 ITAADALAHPYLSPYHD--PTDEPIAEAKFDWNFNDADLPVDTWRVMMYSEILDF 342
I+ +AL H Y++ ++D D P E +D + ++ + V+ W+ ++Y E++D+
Sbjct: 309 ISVDEALKHEYINVWYDAEEVDAPAPE-PYDHSVDEREHTVEQWKELIYEEVMDY 362
>Hs21237736 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 424
Score = 258 bits (660), Expect = 1e-68
Identities = 145/383 (37%), Positives = 219/383 (56%), Gaps = 33/383 (8%)
Query: 3 NEEFIRTQIFGTVFEITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVL 62
+ +F Q+ + F + RY L P+G GA G+VC+A DT+ VA+KK+ +PF
Sbjct: 7 DSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTH 66
Query: 63 AKRTYRELKLLKHLRHENLICLEDIF-----LSPLEDIYFVTELQGTDLHRLLQTRPLEK 117
AKR YREL LLK + H+N+I L ++F L +D+Y V EL +L +++ L+
Sbjct: 67 AKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIHME-LDH 125
Query: 118 QFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLAR--IQDPQMTGY 175
+ + Y LYQ+L G+K++HSAG+IHRDLKPSNI++ +C LKI DFGLAR + MT Y
Sbjct: 126 ERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNFMMTPY 185
Query: 176 VSTRYYRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSP 235
V TRYYRAPE++L Y VDIWS GCI E+++G +F G DH+ Q++ + + LG+P
Sbjct: 186 VVTRYYRAPEVIL-GMGYKENVDIWSVGCIMGELVKGCVIFQGTDHIDQWNKVIEQLGTP 244
Query: 236 PKDVIDTICSENTLKFVTSLPHRDPVPFSSRF------QNLEPDAI------DLLEKMLV 283
+ + + +V + P + F F E D I DLL KMLV
Sbjct: 245 SAEFMKKL-QPTVRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSKMLV 303
Query: 284 FDPKKRITAADALAHPYLSPYHDPTD-EPIAEAKFDWNFNDADLPVDTWRVMMYSEILDF 342
DP KRI+ +AL HPY++ ++DP + E +D + + ++ W+ ++Y E++D+
Sbjct: 304 IDPDKRISVDEALRHPYITVWYDPAEAEAPPPQIYDAQLEEREHAIEEWKELIYKEVMDW 363
Query: 343 H----------QIGDPQINTNAT 355
Q D +++NAT
Sbjct: 364 EERSKNGVVKDQPSDAAVSSNAT 386
>HsM20070143 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 424
Score = 258 bits (658), Expect = 2e-68
Identities = 145/383 (37%), Positives = 219/383 (56%), Gaps = 33/383 (8%)
Query: 3 NEEFIRTQIFGTVFEITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVL 62
+ +F Q+ + F + RY L P+G GA G+VC+A DT+ VA+KK+ +PF
Sbjct: 7 DSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTH 66
Query: 63 AKRTYRELKLLKHLRHENLICLEDIF-----LSPLEDIYFVTELQGTDLHRLLQTRPLEK 117
AKR YREL LLK + H+N+I L ++F L +D+Y V EL +L +++ L+
Sbjct: 67 AKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIHME-LDH 125
Query: 118 QFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLAR--IQDPQMTGY 175
+ + Y LYQ+L G+K++HSAG+IHRDLKPSNI++ +C LKI DFGLAR + MT Y
Sbjct: 126 ERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNFMMTPY 185
Query: 176 VSTRYYRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSP 235
V TRYYRAPE++L Y VDIWS GCI E+++G +F G DH+ Q++ + + LG+P
Sbjct: 186 VVTRYYRAPEVIL-GMGYKENVDIWSVGCIMGELVKGCVIFQGTDHIDQWNKVIEQLGTP 244
Query: 236 PKDVIDTICSENTLKFVTSLPHRDPVPFSSRF------QNLEPDAI------DLLEKMLV 283
+ + + +V + P + F F E D I DLL KMLV
Sbjct: 245 SAEFMKKL-QPTVRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSKMLV 303
Query: 284 FDPKKRITAADALAHPYLSPYHDPTD-EPIAEAKFDWNFNDADLPVDTWRVMMYSEILDF 342
DP KRI+ +AL HPY++ ++DP + E +D + + ++ W+ ++Y E++D+
Sbjct: 304 IDPDKRISVDEALRHPYITVWYDPAEAEAPPPQIYDAQLEEREHAIEEWKELIYKEVMDW 363
Query: 343 H----------QIGDPQINTNAT 355
Q D +++NAT
Sbjct: 364 EERSKNGVVKDQPPDAAVSSNAT 386
>CE27574 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 463
Score = 258 bits (658), Expect = 2e-68
Identities = 146/350 (41%), Positives = 211/350 (59%), Gaps = 24/350 (6%)
Query: 18 ITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLR 77
+ RY NL +G GA G+VCSA DT+ ++ VAIKK+ +PF AKR YRELKL+ +
Sbjct: 115 VLKRYQNLRLIGSGAQGIVCSAFDTVRNEQVAIKKLSRPFQNVTHAKRAYRELKLMSLVN 174
Query: 78 HENLICLEDIF-----LSPLEDIYFVTELQGTDLHRLLQTRPLEKQFVQYFLYQILRGLK 132
H+N+I + + F L D+Y V EL +L +++Q L+ + + Y LYQ+L G++
Sbjct: 175 HKNIIGILNCFTPQKKLDEFNDLYIVMELMDANLCQVIQM-DLDHERLSYLLYQMLCGIR 233
Query: 133 YVHSAGVIHRDLKPSNILINENCDLKICDFGLAR--IQDPQMTGYVSTRYYRAPEIMLTW 190
++HSAG+IHRDLKPSNI++ +C LKI DFGLAR I+ MT YV TRYYRAPE++L
Sbjct: 234 HLHSAGIIHRDLKPSNIVVRSDCTLKILDFGLARTAIEAFMMTPYVVTRYYRAPEVIL-G 292
Query: 191 QKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLK 250
Y VD+WS GCIF E+I G+ LFPG DH+ Q++ I + LG+P + ++ +
Sbjct: 293 MGYKENVDVWSIGCIFGELIRGRVLFPGGDHIDQWTRIIEQLGTPDRSFLERL-QPTVRN 351
Query: 251 FVTSLPHRDPVPFSSRF-QNLEP-----------DAIDLLEKMLVFDPKKRITAADALAH 298
+V + P PF F N+ P A DLL +MLV DP++RI+ DAL H
Sbjct: 352 YVENRPRYQATPFEVLFSDNMFPMTADSSRLTGAQARDLLSRMLVIDPERRISVDDALRH 411
Query: 299 PYLSPYHDPTDEPIAEAKFDWNFN-DADLPVDTWRVMMYSEILDFHQIGD 347
PY++ + D E A ++ N D + VD+WR ++ E+ D+ + D
Sbjct: 412 PYVNVWFDEI-EVYAPPPLPYDHNMDVEQNVDSWREHIFRELTDYARTHD 460
>Hs21237739 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 382
Score = 257 bits (657), Expect = 2e-68
Identities = 140/362 (38%), Positives = 212/362 (57%), Gaps = 23/362 (6%)
Query: 3 NEEFIRTQIFGTVFEITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVL 62
+ +F Q+ + F + RY L P+G GA G+VC+A DT+ VA+KK+ +PF
Sbjct: 7 DSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTH 66
Query: 63 AKRTYRELKLLKHLRHENLICLEDIF-----LSPLEDIYFVTELQGTDLHRLLQTRPLEK 117
AKR YREL LLK + H+N+I L ++F L +D+Y V EL +L +++ L+
Sbjct: 67 AKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIHME-LDH 125
Query: 118 QFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLAR--IQDPQMTGY 175
+ + Y LYQ+L G+K++HSAG+IHRDLKPSNI++ +C LKI DFGLAR + MT Y
Sbjct: 126 ERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNFMMTPY 185
Query: 176 VSTRYYRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSP 235
V TRYYRAPE++L Y VDIWS GCI E+++G +F G DH+ Q++ + + LG+P
Sbjct: 186 VVTRYYRAPEVIL-GMGYKENVDIWSVGCIMGELVKGCVIFQGTDHIDQWNKVIEQLGTP 244
Query: 236 PKDVIDTICSENTLKFVTSLPHRDPVPFSSRF------QNLEPDAI------DLLEKMLV 283
+ + + +V + P + F F E D I DLL KMLV
Sbjct: 245 SAEFMKKL-QPTVRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSKMLV 303
Query: 284 FDPKKRITAADALAHPYLSPYHDPTD-EPIAEAKFDWNFNDADLPVDTWRVMMYSEILDF 342
DP KRI+ +AL HPY++ ++DP + E +D + + ++ W+ ++Y E++D+
Sbjct: 304 IDPDKRISVDEALRHPYITVWYDPAEAEAPPPQIYDAQLEEREHAIEEWKELIYKEVMDW 363
Query: 343 HQ 344
+
Sbjct: 364 EE 365
>Hs7706445 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 515
Score = 256 bits (653), Expect = 6e-68
Identities = 137/287 (47%), Positives = 188/287 (64%), Gaps = 14/287 (4%)
Query: 27 PVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHENLICLED 86
P+G GAFG+V S TD + VA+KK+ F V KR +RELK+L +H+N++ D
Sbjct: 131 PIGYGAFGVVWSVTDPRDGKRVALKKMPNVFQNLVSCKRVFRELKMLCFFKHDNVLSALD 190
Query: 87 IFLSP----LEDIYFVTELQGTDLHRLLQT-RPLEKQFVQYFLYQILRGLKYVHSAGVIH 141
I P E+IY VTEL +DLH+++ + +PL V+ FLYQILRGLKY+HSAG++H
Sbjct: 191 ILQPPHIDYFEEIYVVTELMQSDLHKIIVSPQPLSSDHVKVFLYQILRGLKYLHSAGILH 250
Query: 142 RDLKPSNILINENCDLKICDFGLARIQD----PQMTGYVSTRYYRAPEIMLTWQKYNVEV 197
RD+KP N+L+N NC LKICDFGLAR+++ MT V T+YYRAPEI++ + Y+ +
Sbjct: 251 RDIKPGNLLVNSNCVLKICDFGLARVEELDESRHMTQEVVTQYYRAPEILMGSRHYSNAI 310
Query: 198 DIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLKFVTSLPH 257
DIWS GCIFAE++ + LF + + Q +ITDLLG+P + + T C E + PH
Sbjct: 311 DIWSVGCIFAELLGRRILFQAQSPIQQLDLITDLLGTPSLEAMRTAC-EGAKAHILRGPH 369
Query: 258 RD---PVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPYL 301
+ PV ++ Q +A+ LL +MLVFDP KRI+A DALAHPYL
Sbjct: 370 KQPSLPVLYTLSSQATH-EAVHLLCRMLVFDPSKRISAKDALAHPYL 415
>Hs4506095 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 384
Score = 255 bits (651), Expect = 1e-67
Identities = 139/362 (38%), Positives = 211/362 (57%), Gaps = 23/362 (6%)
Query: 3 NEEFIRTQIFGTVFEITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVL 62
+ F +I + F + RY NL P+G GA G+VC+A D + + VAIKK+ +PF
Sbjct: 7 DNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTH 66
Query: 63 AKRTYRELKLLKHLRHENLICLEDIF-----LSPLEDIYFVTELQGTDLHRLLQTRPLEK 117
AKR YREL L+K + H+N+I L ++F L +D+Y V EL +L +++Q L+
Sbjct: 67 AKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQME-LDH 125
Query: 118 QFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDP--QMTGY 175
+ + Y LYQ+L G+K++HSAG+IHRDLKPSNI++ +C LKI DFGLAR MT Y
Sbjct: 126 ERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPY 185
Query: 176 VSTRYYRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSP 235
V TRYYRAPE++L Y VD+WS GCI EM+ K LFPG+D++ Q++ + + LG+P
Sbjct: 186 VVTRYYRAPEVIL-GMGYKENVDLWSVGCIMGEMVCHKILFPGRDYIDQWNKVIEQLGTP 244
Query: 236 PKDVIDTICSENTLKFVTSLPHRDPVPFSSRFQNL------------EPDAIDLLEKMLV 283
+ + + +V + P F F ++ A DLL KMLV
Sbjct: 245 CPEFMKKL-QPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSKMLV 303
Query: 284 FDPKKRITAADALAHPYLSPYHDPTDEPIAEAKF-DWNFNDADLPVDTWRVMMYSEILDF 342
D KRI+ +AL HPY++ ++DP++ K D ++ + ++ W+ ++Y E++D
Sbjct: 304 IDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEVMDL 363
Query: 343 HQ 344
+
Sbjct: 364 EE 365
>Hs20986523 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 427
Score = 255 bits (651), Expect = 1e-67
Identities = 139/362 (38%), Positives = 211/362 (57%), Gaps = 23/362 (6%)
Query: 3 NEEFIRTQIFGTVFEITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVL 62
+ F +I + F + RY NL P+G GA G+VC+A D + + VAIKK+ +PF
Sbjct: 7 DNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTH 66
Query: 63 AKRTYRELKLLKHLRHENLICLEDIF-----LSPLEDIYFVTELQGTDLHRLLQTRPLEK 117
AKR YREL L+K + H+N+I L ++F L +D+Y V EL +L +++Q L+
Sbjct: 67 AKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQME-LDH 125
Query: 118 QFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDP--QMTGY 175
+ + Y LYQ+L G+K++HSAG+IHRDLKPSNI++ +C LKI DFGLAR MT Y
Sbjct: 126 ERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPY 185
Query: 176 VSTRYYRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSP 235
V TRYYRAPE++L Y VD+WS GCI EM+ K LFPG+D++ Q++ + + LG+P
Sbjct: 186 VVTRYYRAPEVIL-GMGYKENVDLWSVGCIMGEMVCHKILFPGRDYIDQWNKVIEQLGTP 244
Query: 236 PKDVIDTICSENTLKFVTSLPHRDPVPFSSRFQNL------------EPDAIDLLEKMLV 283
+ + + +V + P F F ++ A DLL KMLV
Sbjct: 245 CPEFMKKL-QPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSKMLV 303
Query: 284 FDPKKRITAADALAHPYLSPYHDPTDEPIAEAKF-DWNFNDADLPVDTWRVMMYSEILDF 342
D KRI+ +AL HPY++ ++DP++ K D ++ + ++ W+ ++Y E++D
Sbjct: 304 IDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEVMDL 363
Query: 343 HQ 344
+
Sbjct: 364 EE 365
>YKL161c [T] KOG0660 Mitogen-activated protein kinase
Length = 433
Score = 251 bits (641), Expect = 2e-66
Identities = 138/350 (39%), Positives = 206/350 (58%), Gaps = 17/350 (4%)
Query: 12 FGTVFEITNRYTNLNPVGMGAFGLVCSATDTLTSQP--VAIKKIMKPFSTSVLAKRTYRE 69
FG F + + +G G+ L+CS+T T +++ VAI+KI F + KRT RE
Sbjct: 13 FGQDFILNKHFHLTGKIGRGSHSLICSSTYTESNEETHVAIRKIPNAFGNKLSCKRTLRE 72
Query: 70 LKLLKHLR-HENLICL--EDIFLSP---LEDIYFVTELQGTDLHRLLQTRP-LEKQFVQY 122
LKLL+HLR H N++ L DI P L +Y EL DL +++++ LE Q
Sbjct: 73 LKLLRHLRGHPNIVWLFDTDIVFYPNGALNGVYLYEELMECDLSQIIRSEQRLEDAHFQS 132
Query: 123 FLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLA-------RIQDPQMTGY 175
F+YQIL LKY+HSA V+H DLKP N+L+N +C LKIC+FGL+ ++ D + GY
Sbjct: 133 FIYQILCALKYIHSANVLHCDLKPKNLLVNSDCQLKICNFGLSCSYSENHKVNDGFIKGY 192
Query: 176 VSTRYYRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSP 235
+++ +Y+APEI+L +Q+ VDIWS GCI AE++ KP+F GKD+V + I +LG+P
Sbjct: 193 ITSIWYKAPEILLNYQECTKAVDIWSTGCILAELLGRKPMFEGKDYVDHLNHILQILGTP 252
Query: 236 PKDVIDTICSENTLKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADA 295
P++ + I S+ ++ + F S P+A++LL+KML FDPKKRIT DA
Sbjct: 253 PEETLQEIASQKVYNYIFQFGNIPGRSFESILPGANPEALELLKKMLEFDPKKRITVEDA 312
Query: 296 LAHPYLSPYHDPTDEPIAEAKFDWNFNDADLPVDTWRVMMYSEILDFHQI 345
L HPYLS +HD +E + F + F + + ++ E+ DF ++
Sbjct: 313 LEHPYLSMWHDIDEEFSCQKTFRFEFEHIESMAELGNEVI-KEVFDFRKV 361
>Hs20986499 [T] KOG0660 Mitogen-activated protein kinase
Length = 677
Score = 242 bits (617), Expect = 9e-64
Identities = 121/248 (48%), Positives = 169/248 (67%), Gaps = 8/248 (3%)
Query: 104 TDLHRLLQT-RPLEKQFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDF 162
+DLH+++ + +PL + V+YFLYQ+LRGLKY+HSA VIHRDLKPSN+L+NENC+LKI DF
Sbjct: 3 SDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDF 62
Query: 163 GLAR--IQDPQ-----MTGYVSTRYYRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPL 215
G+AR P MT YV+TR+YRAPE+ML+ +Y +D+WS GCIF EM+ + L
Sbjct: 63 GMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARRQL 122
Query: 216 FPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLKFVTSLPHRDPVPFSSRFQNLEPDAI 275
FPGK++VHQ +I +LG+P VI + +E ++ SLP R PVP+ + + + A+
Sbjct: 123 FPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQAL 182
Query: 276 DLLEKMLVFDPKKRITAADALAHPYLSPYHDPTDEPIAEAKFDWNFNDADLPVDTWRVMM 335
LL +ML F+P RI+AA AL HP+L+ YHDP DEP FD+ F+ L + + +
Sbjct: 183 SLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKEAI 242
Query: 336 YSEILDFH 343
+EI DFH
Sbjct: 243 VAEIEDFH 250
>7295173 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 474
Score = 241 bits (615), Expect = 2e-63
Identities = 128/287 (44%), Positives = 184/287 (63%), Gaps = 14/287 (4%)
Query: 27 PVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHENLICLED 86
P+G GAFG+V + TD + VA+KK+ F + V +KR +RELK+L +HEN++ D
Sbjct: 45 PIGYGAFGVVWAVTDPRDGRRVALKKLPNVFQSLVSSKRVFRELKMLCFFKHENVLSALD 104
Query: 87 IFLSP----LEDIYFVTELQGTDLHRLLQT-RPLEKQFVQYFLYQILRGLKYVHSAGVIH 141
I P ++IY +TEL +DLH+++ + + L ++ FLYQILRGLKY+HSA ++H
Sbjct: 105 ILQPPHLDFFQEIYVITELLQSDLHKIIVSPQHLSADHIKVFLYQILRGLKYLHSARILH 164
Query: 142 RDLKPSNILINENCDLKICDFGLARIQDP----QMTGYVSTRYYRAPEIMLTWQKYNVEV 197
RD+KP N+L+N NC LKICDFGLAR+++P MT V T+YYRAPEI++ + Y+ V
Sbjct: 165 RDIKPGNLLVNSNCVLKICDFGLARVEEPDQAKHMTQEVVTQYYRAPEILMGARHYSSAV 224
Query: 198 DIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLKFVTSLPH 257
D+WS GCIF E++ + LF ++ V Q +IT+LLG+P + + C + P
Sbjct: 225 DVWSVGCIFGELLGRRILFQAQNPVQQLELITELLGTPTMEDMRHACEGARTHMLRRAP- 283
Query: 258 RDPVPFSSRF---QNLEPDAIDLLEKMLVFDPKKRITAADALAHPYL 301
P FS + + +A+ LL +MLVFDP KRI+ DALAHPYL
Sbjct: 284 -KPPSFSVLYTLSSHATHEAVHLLCQMLVFDPDKRISVTDALAHPYL 329
>CE29466 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 390
Score = 238 bits (607), Expect = 1e-62
Identities = 143/360 (39%), Positives = 211/360 (57%), Gaps = 29/360 (8%)
Query: 7 IRTQIFG--TVFEITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAK 64
IR I G + F I RY NL+ + GA G V A D +T+Q VAIKK+ +PF ++ AK
Sbjct: 21 IRDPIAGADSTFTIPTRYVNLSFLNAGAQGTVVMADDLVTTQRVAIKKMQQPFVMTMSAK 80
Query: 65 RTYRELKLLKHLRHENLICLEDIF-----LSPLEDIYFVTELQGTDLHRLLQTRPLEKQF 119
R YRE LL ++H N+I L + F LS ++Y V EL +LH ++ L+ +
Sbjct: 81 RAYREFILLTTIKHPNIIRLLNAFTPDTSLSTFREVYLVMELMTHNLHEVIHRLRLDHKT 140
Query: 120 VQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQD----PQMTGY 175
+ +F+YQ L +K++H++GVIHRDLKPSNI++N+ C LK+ DFGLAR ++ +M+ Y
Sbjct: 141 LSFFVYQSLCAIKHLHNSGVIHRDLKPSNIVVNDRCVLKVLDFGLARKKNVDTSMRMSDY 200
Query: 176 VSTRYYRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSP 235
V TRYYRAPE++L Y+ +VDIWS GCIFAEMI LFPGKD + Q++ I +LG+P
Sbjct: 201 VVTRYYRAPEVIL-GLPYSEKVDIWSVGCIFAEMINHTVLFPGKDRIDQWTKIYSVLGTP 259
Query: 236 PKDVIDTICSENTLKFVTSLPHRDPVPFSSRF--QNLEPD------------AIDLLEKM 281
I + ++ +V SLP FS N P+ A DLL M
Sbjct: 260 DDHFISQL-GQSAAMYVRSLPRHQARAFSEIVPDTNFLPETENPRVHLTPHVARDLLFNM 318
Query: 282 LVFDPKKRITAADALAHPYLSPY--HDPTDEPIAEAKFDWNFNDADLPVDTWRVMMYSEI 339
L +P++R + DAL HPY+ + D + P +E ++D + AD + W+ ++++E+
Sbjct: 319 LKINPEERYSVEDALNHPYVKLWFKDDEVNAPASENRYDQEIDFADKTLIEWKELIFNEV 378
>CE02602_1 [T] KOG0660 Mitogen-activated protein kinase
Length = 342
Score = 233 bits (594), Expect = 4e-61
Identities = 124/300 (41%), Positives = 184/300 (61%), Gaps = 19/300 (6%)
Query: 21 RYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHEN 80
+Y +G GAFG+VC A D+ ++ VAIKKI + F AK RE+++ + L HEN
Sbjct: 43 QYLAQENLGAGAFGVVCRAIDSKLNKQVAIKKITRVFKNQSTAKCALREIRITRELSHEN 102
Query: 81 LICLEDIFLSPL---EDIYFVTELQGTDLHRLLQT-RPLEKQFVQYFLYQILRGLKYVHS 136
+I D+ + +DIY V +L TDL +L++ + L ++ QYF YQIL+GLKY+HS
Sbjct: 103 IINSTDVLMRESGSGQDIYIVMDLMETDLLSVLKSNQTLNEKHFQYFFYQILKGLKYLHS 162
Query: 137 AGVIHRDLKPSNILINENCDLKICDFGLARIQDPQMTG---------------YVSTRYY 181
AG+IHRDLKP+N+L+NE+C LKI DFG++R T YVST +Y
Sbjct: 163 AGIIHRDLKPANLLLNEDCSLKIADFGMSRSGPSTKTTPNTSPNAHISGDLSQYVSTLWY 222
Query: 182 RAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVID 241
RAPEI+L+ +Y+ +VDIWSAGCI AEM+ +P+F G D Q ++ + LG+P + VI
Sbjct: 223 RAPEILLSMGEYDTQVDIWSAGCILAEMLLLRPIFTGTDSYSQIQLLIEYLGTPDEQVIR 282
Query: 242 TICSENTLKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPYL 301
I S + +++S + P+PF++ F N +A +++ KML P KR +A L P++
Sbjct: 283 RIKSPSIRDYISSFGPKTPLPFTAMFPNASIEARNIVSKMLQISPWKRFSAEQLLEEPFV 342
>CE29478 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 437
Score = 231 bits (588), Expect = 2e-60
Identities = 122/287 (42%), Positives = 180/287 (62%), Gaps = 12/287 (4%)
Query: 27 PVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHENLICLED 86
P+G GAFG+V S TD + + VA+KK+ F KR +RE+K+L RH+N++ L D
Sbjct: 48 PIGYGAFGVVWSVTDPRSGKRVALKKMPNVFQNLASCKRVFREIKMLSSFRHDNVLSLLD 107
Query: 87 IFL----SPLEDIYFVTELQGTDLHRLLQT-RPLEKQFVQYFLYQILRGLKYVHSAGVIH 141
I S +++Y +TEL +DLH+++ + + L V+ F+YQILRGLKY+H+A ++H
Sbjct: 108 ILQPANPSFFQELYVLTELMQSDLHKIIVSPQALTPDHVKVFVYQILRGLKYLHTANILH 167
Query: 142 RDLKPSNILINENCDLKICDFGLARIQDPQ----MTGYVSTRYYRAPEIMLTWQKYNVEV 197
RD+KP N+L+N NC LKICDFGLAR D + MT V T+YYRAPE+++ ++Y V
Sbjct: 168 RDIKPGNLLVNSNCILKICDFGLARTWDQRDRLNMTHEVVTQYYRAPELLMGARRYTGAV 227
Query: 198 DIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTIC---SENTLKFVTS 254
DIWS GCIFAE+++ K LF + Q +I DLLG+P ++ + C + L+
Sbjct: 228 DIWSVGCIFAELLQRKILFQAAGPIEQLQMIIDLLGTPSQEAMKYACEGAKNHVLRAGLR 287
Query: 255 LPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPYL 301
P + + + +A+DLL+K+L FDP KRI+ +AL H YL
Sbjct: 288 APDTQRLYKIASPDDKNHEAVDLLQKLLHFDPDKRISVEEALQHRYL 334
>CE29477 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 462
Score = 231 bits (588), Expect = 2e-60
Identities = 122/287 (42%), Positives = 180/287 (62%), Gaps = 12/287 (4%)
Query: 27 PVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHENLICLED 86
P+G GAFG+V S TD + + VA+KK+ F KR +RE+K+L RH+N++ L D
Sbjct: 73 PIGYGAFGVVWSVTDPRSGKRVALKKMPNVFQNLASCKRVFREIKMLSSFRHDNVLSLLD 132
Query: 87 IFL----SPLEDIYFVTELQGTDLHRLLQT-RPLEKQFVQYFLYQILRGLKYVHSAGVIH 141
I S +++Y +TEL +DLH+++ + + L V+ F+YQILRGLKY+H+A ++H
Sbjct: 133 ILQPANPSFFQELYVLTELMQSDLHKIIVSPQALTPDHVKVFVYQILRGLKYLHTANILH 192
Query: 142 RDLKPSNILINENCDLKICDFGLARIQDPQ----MTGYVSTRYYRAPEIMLTWQKYNVEV 197
RD+KP N+L+N NC LKICDFGLAR D + MT V T+YYRAPE+++ ++Y V
Sbjct: 193 RDIKPGNLLVNSNCILKICDFGLARTWDQRDRLNMTHEVVTQYYRAPELLMGARRYTGAV 252
Query: 198 DIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTIC---SENTLKFVTS 254
DIWS GCIFAE+++ K LF + Q +I DLLG+P ++ + C + L+
Sbjct: 253 DIWSVGCIFAELLQRKILFQAAGPIEQLQMIIDLLGTPSQEAMKYACEGAKNHVLRAGLR 312
Query: 255 LPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPYL 301
P + + + +A+DLL+K+L FDP KRI+ +AL H YL
Sbjct: 313 APDTQRLYKIASPDDKNHEAVDLLQKLLHFDPDKRISVEEALQHRYL 359
>CE29476 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 634
Score = 231 bits (588), Expect = 2e-60
Identities = 122/287 (42%), Positives = 180/287 (62%), Gaps = 12/287 (4%)
Query: 27 PVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHENLICLED 86
P+G GAFG+V S TD + + VA+KK+ F KR +RE+K+L RH+N++ L D
Sbjct: 245 PIGYGAFGVVWSVTDPRSGKRVALKKMPNVFQNLASCKRVFREIKMLSSFRHDNVLSLLD 304
Query: 87 IFL----SPLEDIYFVTELQGTDLHRLLQT-RPLEKQFVQYFLYQILRGLKYVHSAGVIH 141
I S +++Y +TEL +DLH+++ + + L V+ F+YQILRGLKY+H+A ++H
Sbjct: 305 ILQPANPSFFQELYVLTELMQSDLHKIIVSPQALTPDHVKVFVYQILRGLKYLHTANILH 364
Query: 142 RDLKPSNILINENCDLKICDFGLARIQDPQ----MTGYVSTRYYRAPEIMLTWQKYNVEV 197
RD+KP N+L+N NC LKICDFGLAR D + MT V T+YYRAPE+++ ++Y V
Sbjct: 365 RDIKPGNLLVNSNCILKICDFGLARTWDQRDRLNMTHEVVTQYYRAPELLMGARRYTGAV 424
Query: 198 DIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTIC---SENTLKFVTS 254
DIWS GCIFAE+++ K LF + Q +I DLLG+P ++ + C + L+
Sbjct: 425 DIWSVGCIFAELLQRKILFQAAGPIEQLQMIIDLLGTPSQEAMKYACEGAKNHVLRAGLR 484
Query: 255 LPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPYL 301
P + + + +A+DLL+K+L FDP KRI+ +AL H YL
Sbjct: 485 APDTQRLYKIASPDDKNHEAVDLLQKLLHFDPDKRISVEEALQHRYL 531
>CE29318 [T] KOG0660 Mitogen-activated protein kinase
Length = 474
Score = 229 bits (584), Expect = 6e-60
Identities = 135/341 (39%), Positives = 203/341 (58%), Gaps = 25/341 (7%)
Query: 28 VGMGAFGLVCSATDTLTS---QPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHENLICL 84
+G G+FG V + + VAIKK+ +PF A+R +RE KLL+ +RH+N+IC
Sbjct: 124 LGGGSFGNVIKTSAVCRDGLRRYVAIKKMREPFFDPHHARRIFRETKLLQLMRHDNIICA 183
Query: 85 EDIFLSPLE----DIYFVTELQGTDLHRLLQT------RPLEKQFVQYFLYQILRGLKYV 134
DI+ E D+Y VTE G L+++L+ R L + +++ +YQI+R LKY+
Sbjct: 184 LDIYTPDEENDFRDVYVVTEFAGRSLYQILKQQRDYGRRVLTDEHIKFIIYQIIRALKYI 243
Query: 135 HSAGVIHRDLKPSNILINENCDLKICDFGLARI---QDPQMTGYVSTRYYRAPEIMLTWQ 191
HSA +IHRDLKP N+ + ++ DL I DFGLAR +D +T YV TR+YR+PE+ + W+
Sbjct: 244 HSANIIHRDLKPGNLALTDDSDLMILDFGLARSLEKKDTSLTQYVQTRWYRSPEV-IYWK 302
Query: 192 --KYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTL 249
Y D+WS GCI AE++ G+PLFPG + Q+ IT L GSP ++++ I ++N+
Sbjct: 303 IDSYTNLADMWSLGCIAAELLTGEPLFPGDEPNAQYQRITQLCGSPDEELLTKIENDNSS 362
Query: 250 KF---VTSLPHRDPVPFSSRF--QNLEPDAIDLLEKMLVFDPKKRITAADALAHPYLSPY 304
+ S F F N D IDLLEK+LV DP+KRIT +A+ HPYL+ +
Sbjct: 363 AIKAVIQSYTTHKRRNFRDVFSAHNPSEDFIDLLEKLLVLDPEKRITVEEAIQHPYLAEF 422
Query: 305 HDPTDEPIAEAKFDWNFNDADLPVDTWRVMMYSEILDFHQI 345
P DEP A+ FD + + A + WR ++ EI+++ ++
Sbjct: 423 SLPEDEPRADHIFDLDDSQARTRFE-WRDAVWKEIMNYKRL 462
>Hs4506091 [T] KOG0660 Mitogen-activated protein kinase
Length = 721
Score = 221 bits (563), Expect = 2e-57
Identities = 127/324 (39%), Positives = 191/324 (58%), Gaps = 27/324 (8%)
Query: 16 FEITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKH 75
F++ +RY +L P+G G GLV SA D + VAIKKI+ SV K RE+K+++
Sbjct: 14 FDLGSRYMDLKPLGCGGNGLVFSAVDNDCDKRVAIKKIVLTDPQSV--KHALREIKIIRR 71
Query: 76 LRHENLICLEDIF-------------LSPLEDIYFVTELQGTDLHRLLQTRPLEKQFVQY 122
L H+N++ + +I L+ L +Y V E TDL +L+ PL ++ +
Sbjct: 72 LDHDNIVKVFEILGPSGSQLTDDVGSLTELNSVYIVQEYMETDLANVLEQGPLLEEHARL 131
Query: 123 FLYQILRGLKYVHSAGVIHRDLKPSNILIN-ENCDLKICDFGLARIQDPQMT--GYVS-- 177
F+YQ+LRGLKY+HSA V+HRDLKP+N+ IN E+ LKI DFGLARI DP + G++S
Sbjct: 132 FMYQLLRGLKYIHSANVLHRDLKPANLFINTEDLVLKIGDFGLARIMDPHYSHKGHLSEG 191
Query: 178 --TRYYRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSP 235
T++YR+P ++L+ Y +D+W+AGCIFAEM+ GK LF G + Q +I + +
Sbjct: 192 LVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLTGKTLFAGAHELEQMQLILESIPVV 251
Query: 236 PKDVIDTICSENTLKFVTSL--PHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAA 293
++ + S + + PH+ P + + +A+D LE++L F P R+TA
Sbjct: 252 HEEDRQELLSVIPVYIRNDMTEPHK---PLTQLLPGISREALDFLEQILTFSPMDRLTAE 308
Query: 294 DALAHPYLSPYHDPTDEPIAEAKF 317
+AL+HPY+S Y P DEPI+ F
Sbjct: 309 EALSHPYMSIYSFPMDEPISSHPF 332
>YPR054w [T] KOG0660 Mitogen-activated protein kinase
Length = 388
Score = 220 bits (560), Expect = 4e-57
Identities = 136/347 (39%), Positives = 194/347 (55%), Gaps = 23/347 (6%)
Query: 18 ITNRYTNLNPVGMGAFGLVCSATDTLTSQP--VAIKKIMKPFSTSVLAKRTYRELKLLK- 74
I Y + +G GA+G VCS S +A+KKI F+ +L KR RELK +
Sbjct: 34 IPGYYEIIQFLGKGAYGTVCSVKFKGRSPAARIAVKKISNIFNKEILLKRAIRELKFMNF 93
Query: 75 ---HLRHENLICLEDIFLSPLEDIYFVTELQGTDLHRLLQTRPLEKQF-VQYFLYQILRG 130
H NLI LE + SP + +Y EL DL +++ + +F ++YFLYQIL G
Sbjct: 94 FKGHKNIVNLIDLEIVTSSPYDGLYCYQELIDYDLAKVIHSSVQLSEFHIKYFLYQILCG 153
Query: 131 LKYVHSAGVIHRDLKPSNILINENCDLKICDFGLAR-----------IQDPQMTGYVSTR 179
LKY+HSA VIHRDLKP NIL N LKICDFGLAR P +T YV+TR
Sbjct: 154 LKYIHSADVIHRDLKPGNILCTLNGCLKICDFGLARGIHAGFFKCHSTVQPHITNYVATR 213
Query: 180 YYRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDV 239
+YRAPE++L+ Q Y+ VDIW+ GCI AE KP+F G+D +HQ I +LG+P KD+
Sbjct: 214 WYRAPELLLSNQPYSKSVDIWAVGCILAEFYARKPVFMGRDSMHQIFEIIKVLGTPDKDI 273
Query: 240 I---DTICSENTLKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADAL 296
+ TI + N K ++ P +P+S+ F +AI+L+E +L +D R+ A+
Sbjct: 274 LIKFGTIKAWNLGK-NSNNPVYKKIPWSNIFPFASHEAINLIESLLHWDSTHRLNVEQAI 332
Query: 297 AHPYLSPYHDPTDEPIA-EAKFDWNFNDADLPVDTWRVMMYSEILDF 342
+HP+L+ P DEP+ + FD+ + + R + E+ +F
Sbjct: 333 SHPFLNEVRKPDDEPVCLQGPFDFTYESELNSMSKLRDYLVEEVKNF 379
>CE17305 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 375
Score = 219 bits (558), Expect = 6e-57
Identities = 135/352 (38%), Positives = 198/352 (55%), Gaps = 33/352 (9%)
Query: 13 GTVFEITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKL 72
G F I RY NL + +GA G+V A D +T+Q VAIKK+ +PF ++ A+R YRE L
Sbjct: 20 GITFTIPTRYVNLKFLNVGAQGIVVMADDLVTTQRVAIKKMQQPFLLTMSARRAYREFIL 79
Query: 73 LKHLRHENLICLEDIF-----LSPLEDIYFVTELQGTDLHRLLQTRPLEKQFVQYFLYQI 127
L L+H N+I L + F LS +++Y V E +LH ++ L+ + + + +YQ
Sbjct: 80 LTTLKHPNIIRLLNAFTPDTSLSSFQEVYLVMEFMTHNLHEVIHRLRLDHETLSFLVYQS 139
Query: 128 LRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQ--DPQMTGYVSTRYYRAPE 185
L +K++H+ G IHRDLKPSNI++NE C LK+ DFGLAR + D +M+ YV TRYYRAPE
Sbjct: 140 LCAIKHLHNLGFIHRDLKPSNIVVNERCVLKVLDFGLARRRNVDMRMSDYVGTRYYRAPE 199
Query: 186 IMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICS 245
++L Y+ +VDIWS GCI AEMI LFPGKD Q++ I+ +L +P I+ +
Sbjct: 200 VIL-GLNYSEKVDIWSVGCILAEMINHTVLFPGKDIRDQWTQISSVLRTPDDHFINQLEP 258
Query: 246 ENTLKFVTSLPHRDPVPFSSRFQNLEPD------------------AIDLLEKMLVFDPK 287
+ +V SLP + F + PD A DLL ML +P+
Sbjct: 259 IGAV-YVRSLPQH----LARAFNEIVPDSNFLPETENPKDHLTLHMARDLLFNMLKINPE 313
Query: 288 KRITAADALAHPYLSPYHDPTDEPIAEAKFDWNFNDADLPVDTWRVMMYSEI 339
+R + DAL HPY D + P +E D + D + W+ ++++E+
Sbjct: 314 ERYSVEDALNHPY--TMDDEVNAPASEIPDDEVNDIDDWTLIEWKRLIFNEV 363
>CE29020 [T] KOG0660 Mitogen-activated protein kinase
Length = 470
Score = 216 bits (550), Expect = 5e-56
Identities = 117/327 (35%), Positives = 189/327 (57%), Gaps = 15/327 (4%)
Query: 28 VGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHL-RHENLICLED 86
+G GA+G+V A D + + VA+KKI F ++RT+RE+ L+ +H N+I L +
Sbjct: 19 LGKGAYGIVWKAYDKRSRETVALKKIFDAFRNPTDSQRTFREVMFLQEFGKHPNVIKLYN 78
Query: 87 IFLSPLE-DIYFVTELQGTDLHRLLQTRPLEKQF-VQYFLYQILRGLKYVHSAGVIHRDL 144
IF + + DIY E DLH +++ + K QY + Q+ R ++++HS V+HRDL
Sbjct: 79 IFRADNDRDIYLAFEFMEADLHNVIKKGSILKDVHKQYIMCQLFRAIRFLHSGNVLHRDL 138
Query: 145 KPSNILINENCDLKICDFGLAR----IQD-------PQMTGYVSTRYYRAPEIMLTWQKY 193
KPSN+L++ +C +K+ DFGLAR ++D P +T YV+TR+YR+PEI+L ++Y
Sbjct: 139 KPSNVLLDADCRVKLADFGLARSLSSLEDYPEGQKMPDLTEYVATRWYRSPEILLAAKRY 198
Query: 194 NVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLKFVT 253
VD+WS GCI AEM+ G+ LFPG ++Q I + + P + I +I S +
Sbjct: 199 TKGVDMWSLGCILAEMLIGRALFPGSSTINQIERIMNTIAKPSRADIASIGSHYAASVLE 258
Query: 254 SLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPYLSPYHDPTDEPIA 313
+P R P + AID+++++L+F P+KR+T L HPY+ +H+P++EP+
Sbjct: 259 KMPQRPRKPLDLIITQSQTAAIDMVQRLLIFAPQKRLTVEQCLVHPYVVQFHNPSEEPVL 318
Query: 314 EAKFDWNFND-ADLPVDTWRVMMYSEI 339
+ D L +D +R +Y I
Sbjct: 319 NYEVYPPLPDHIQLSIDDYRDRLYEMI 345
>CE27220 [T] KOG0660 Mitogen-activated protein kinase
Length = 472
Score = 209 bits (532), Expect = 7e-54
Identities = 111/307 (36%), Positives = 180/307 (58%), Gaps = 27/307 (8%)
Query: 22 YTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHENL 81
Y +G GAFG+VC A +T ++Q VAIKK+ +T LA+RT RE+++L+++ H N+
Sbjct: 82 YEPTQNIGSGAFGIVCEAVETSSNQKVAIKKVAHASATPTLARRTLREIRVLRYINHPNI 141
Query: 82 ICLEDIFLS--PLE-DIYFVTELQGTDLHRLLQTR--PLEKQFVQYFLYQILRGLKYVHS 136
+ L DIF + PL D++ V +L +LH ++ PLE+ ++ FL Q+LRGL+Y+H+
Sbjct: 142 VPLRDIFRTKGPLGIDVFLVMDLMQNNLHHIIYGNEDPLEEHYINAFLGQLLRGLEYLHA 201
Query: 137 AGVIHRDLKPSNILINENCDLKICDFGLARIQDPQ------------MTGYVSTRYYRAP 184
A + HRDLKPSN+L+N++ L+I DFG+A+ D MT +V+T YRAP
Sbjct: 202 ACIAHRDLKPSNLLVNQDGTLRIADFGMAKCADNSSKKHDDEEHCYYMTQHVATLPYRAP 261
Query: 185 EIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTIC 244
E++ +++ VD+W+ GCIF EM+ + PG+ Q ++ +LG PP++VI+ +
Sbjct: 262 ELLFVLPEHSTAVDMWAVGCIFGEMVIRNEILPGRSVQGQIKMLLTMLGQPPQEVINEVR 321
Query: 245 SENTLKFVTSLPHR-----DPVPF-----SSRFQNLEPDAIDLLEKMLVFDPKKRITAAD 294
+ T K + + D + F + D ID ++++ +D +KRI D
Sbjct: 322 CDRTRKLIQDFGRKADAEWDDIMFCKARGDDQIVRGNCDTIDFVKQLFQYDAQKRINIQD 381
Query: 295 ALAHPYL 301
AL HPY+
Sbjct: 382 ALLHPYI 388
>Hs4506089 [T] KOG0660 Mitogen-activated protein kinase
Length = 557
Score = 206 bits (525), Expect = 4e-53
Identities = 119/319 (37%), Positives = 181/319 (56%), Gaps = 21/319 (6%)
Query: 16 FEITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKH 75
+++ R+ + P+G G GLV SA D+ + VA+KKI + S+ K RE+K+++
Sbjct: 14 YDLGGRFVDFQPLGFGVNGLVLSAVDSRACRKVAVKKIALSDARSM--KHALREIKIIRR 71
Query: 76 LRHENLICLEDIFLSPLEDI----------YFVTELQGTDLHRLLQTRPLEKQFVQYFLY 125
L H+N++ + ++ D+ Y V E TDL RLL+ L ++ + F+Y
Sbjct: 72 LDHDNIVKVYEVLGPKGTDLQGELFKFSVAYIVQEYMETDLARLLEQGTLAEEHAKLFMY 131
Query: 126 QILRGLKYVHSAGVIHRDLKPSNILIN-ENCDLKICDFGLARIQDPQMT--GYVS----T 178
Q+LRGLKY+HSA V+HRDLKP+NI I+ E+ LKI DFGLARI D + GY+S T
Sbjct: 132 QLLRGLKYIHSANVLHRDLKPANIFISTEDLVLKIGDFGLARIVDQHYSHKGYLSEGLVT 191
Query: 179 RYYRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKD 238
++YR+P ++L+ Y +D+W+AGCI AEM+ G+ LF G + Q +I + + ++
Sbjct: 192 KWYRSPRLLLSPNNYTKAIDMWAAGCILAEMLTGRMLFAGAHELEQMQLILETIPVIREE 251
Query: 239 VIDTICSENTLKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAH 298
D + + S P + +AID LEK+L F+P R+TA L H
Sbjct: 252 DKDELL--RVMPSFVSSTWEVKRPLRKLLPEVNSEAIDFLEKILTFNPMDRLTAEMGLQH 309
Query: 299 PYLSPYHDPTDEPIAEAKF 317
PY+SPY P DEP ++ F
Sbjct: 310 PYMSPYSCPEDEPTSQHPF 328
>At3g48750 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 294
Score = 199 bits (507), Expect = 5e-51
Identities = 115/288 (39%), Positives = 164/288 (56%), Gaps = 10/288 (3%)
Query: 20 NRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHE 79
++Y + +G G +G+V A D +T++ +A+KKI + RE+ LLK ++H
Sbjct: 2 DQYEKVEKIGEGTYGVVYKARDKVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQHS 61
Query: 80 NLICLEDIFLSPLEDIYFVTELQGTDLHRLLQTRP---LEKQFVQYFLYQILRGLKYVHS 136
N++ +D+ S + +Y V E DL + + + P + ++ +LYQILRG+ Y HS
Sbjct: 62 NIVKYDDVVHSE-KRLYLVFEYLDLDLKKHMDSTPDFSKDLHMIKTYLYQILRGIAYCHS 120
Query: 137 AGVIHRDLKPSNILINENCD-LKICDFGLAR---IQDPQMTGYVSTRYYRAPEIMLTWQK 192
V+HRDLKP N+LI+ + LK+ DFGLAR I T V T +YRAPEI+L
Sbjct: 121 HRVLHRDLKPQNLLIDRRTNSLKLADFGLARAFGIPVRTFTHEVVTLWYRAPEILLGSHH 180
Query: 193 YNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLKFV 252
Y+ VDIWS GCIFAEMI KPLFPG + Q I ++G+P +D + S K
Sbjct: 181 YSTPVDIWSVGCIFAEMISQKPLFPGDSEIDQLFKIFRIMGTPYEDTWRGVTSLPDYK-- 238
Query: 253 TSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPY 300
++ P P + NL+PD +DLL KML+ DP KRI A AL H Y
Sbjct: 239 SAFPKWKPTDLETFVPNLDPDGVDLLSKMLLMDPTKRINARAALEHEY 286
>7291043 [T] KOG0660 Mitogen-activated protein kinase
Length = 392
Score = 199 bits (506), Expect = 7e-51
Identities = 117/313 (37%), Positives = 172/313 (54%), Gaps = 27/313 (8%)
Query: 10 QIFGTVFEITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRE 69
Q ++F++ R +G GA+G+V ATD T VA+KK+ F A+RTYRE
Sbjct: 19 QTVESIFDVRKR------MGKGAYGIVWKATDRRTKNTVALKKVFDAFRDETDAQRTYRE 72
Query: 70 LKLLKHLR-HENLICLEDIFLSPLE-DIYFVTELQGTDLHRLLQT----RPLEKQFVQYF 123
+ L+ R H N++ L DIF + D Y V E +DLH +++ + + K+FV
Sbjct: 73 VIFLRAFRCHPNIVRLVDIFKASNNLDFYLVFEFMESDLHNVIKRGNVLKDVHKRFV--- 129
Query: 124 LYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARI-----------QDPQM 172
+YQ++ +K++HS VIHRDLKPSNILI+ C LK+ DFGLAR QD +
Sbjct: 130 MYQLINAIKFIHSGNVIHRDLKPSNILIDSKCRLKVADFGLARTLSSRRIYDDLEQDGML 189
Query: 173 TGYVSTRYYRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQF-SIITDL 231
T YV+TR+YRAPEI++ + Y +D+W GCI EMI KPLF G V+Q I+T L
Sbjct: 190 TDYVATRWYRAPEILVASRNYTKGIDMWGLGCILGEMIRQKPLFQGTSTVNQIEKIVTSL 249
Query: 232 LGSPPKDVIDTICSENTLKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRIT 291
D+ S ++ ++ +N D I L++ +LV +P R+T
Sbjct: 250 PNVTKLDIASIGPSFGSVLLSRNIQRDRRYSLDEMMKNCCDDGISLVKALLVLNPHNRLT 309
Query: 292 AADALAHPYLSPY 304
A +A+ HPY+S +
Sbjct: 310 AKEAIRHPYVSRF 322
>Hs4502709 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 297
Score = 194 bits (493), Expect = 2e-49
Identities = 109/288 (37%), Positives = 161/288 (55%), Gaps = 10/288 (3%)
Query: 22 YTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHENL 81
YT + +G G +G+V T Q VA+KKI + RE+ LLK LRH N+
Sbjct: 4 YTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNI 63
Query: 82 ICLEDIFLSPLEDIYFVTELQGTDLHRLLQTRP----LEKQFVQYFLYQILRGLKYVHSA 137
+ L+D+ + +Y + E DL + L + P ++ V+ +LYQIL+G+ + HS
Sbjct: 64 VSLQDVLMQDSR-LYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSR 122
Query: 138 GVIHRDLKPSNILINENCDLKICDFGLAR---IQDPQMTGYVSTRYYRAPEIMLTWQKYN 194
V+HRDLKP N+LI++ +K+ DFGLAR I T V T +YR+PE++L +Y+
Sbjct: 123 RVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSARYS 182
Query: 195 VEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLKFVTS 254
VDIWS G IFAE+ KPLF G + Q I LG+P +V + E+ + +
Sbjct: 183 TPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEV--ESLQDYKNT 240
Query: 255 LPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPYLS 302
P P +S +NL+ + +DLL KML++DP KRI+ AL HPY +
Sbjct: 241 FPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFN 288
>7297680 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 297
Score = 193 bits (491), Expect = 4e-49
Identities = 106/290 (36%), Positives = 165/290 (56%), Gaps = 10/290 (3%)
Query: 22 YTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHENL 81
+ + +G G +G+V + LT Q VA+KKI + RE+ LLK L+HEN+
Sbjct: 4 FEKIEKIGEGTYGVVYKGRNRLTGQIVAMKKIRLESDDEGVPSTAIREISLLKELKHENI 63
Query: 82 ICLEDIFLSPLEDIYFVTELQGTDLHRLLQTRPLEK----QFVQYFLYQILRGLKYVHSA 137
+CLED+ + IY + E DL + + + P++K + V+ +LYQI + + H
Sbjct: 64 VCLEDVLMEE-NRIYLIFEFLSMDLKKYMDSLPVDKHMESELVRSYLYQITSAILFCHRR 122
Query: 138 GVIHRDLKPSNILINENCDLKICDFGLAR---IQDPQMTGYVSTRYYRAPEIMLTWQKYN 194
V+HRDLKP N+LI+++ +K+ DFGL R I T + T +YRAPE++L +Y+
Sbjct: 123 RVLHRDLKPQNLLIDKSGLIKVADFGLGRSFGIPVRIYTHEIVTLWYRAPEVLLGSPRYS 182
Query: 195 VEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLKFVTS 254
VDIWS GCIFAEM KPLF G + Q + +L +P +D+ + S K +
Sbjct: 183 CPVDIWSIGCIFAEMATRKPLFQGDSEIDQLFRMFRILKTPTEDIWPGVTSLPDYK--NT 240
Query: 255 LPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPYLSPY 304
P +++ +NL+ + IDL++KML++DP RI+A D L HPY + +
Sbjct: 241 FPCWSTNQLTNQLKNLDANGIDLIQKMLIYDPVHRISAKDILEHPYFNGF 290
>Hs4557439 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 305
Score = 192 bits (488), Expect = 8e-49
Identities = 121/305 (39%), Positives = 168/305 (54%), Gaps = 26/305 (8%)
Query: 22 YTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHENL 81
+ + +G G +G+V A + T Q VA+KKI + RE+ LLK L+H N+
Sbjct: 4 FQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKHPNI 63
Query: 82 ICLEDIFLSPLEDIYFVTELQGTDLHRLLQTRP---LEKQFVQYFLYQILRGLKYVHSAG 138
+ L D+ + + +Y V E DL + + + P L ++ +L+Q+L+G+ + HS
Sbjct: 64 VRLLDVVHNERK-LYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQLLQGVSFCHSHR 122
Query: 139 VIHRDLKPSNILINENCDLKICDFGLARIQDPQMTGY---VSTRYYRAPEIMLTWQKYNV 195
VIHRDLKP N+LINE +K+ DFGLAR + Y V T +YRAPEI+L + Y
Sbjct: 123 VIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSKFYTT 182
Query: 196 EVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLKFVTSL 255
VDIWS GCIFAEM+ K LFPG + Q I +LG+P SE+T VT L
Sbjct: 183 AVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTP---------SEDTWPGVTQL 233
Query: 256 P-HRDPVPFSSR------FQNLEPDAIDLLEKMLVFDPKKRITAADALAHPYLSPYHDPT 308
P ++ P +R NLEP+ DLL ++L +DP +RITA ALAHPY S P
Sbjct: 234 PDYKGSFPKWTRKGLEEIVPNLEPEGRDLLMQLLQYDPSQRITAKTALAHPYFS---SPE 290
Query: 309 DEPIA 313
P A
Sbjct: 291 PSPAA 295
>At1g73690 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 398
Score = 189 bits (480), Expect = 7e-48
Identities = 120/320 (37%), Positives = 173/320 (53%), Gaps = 16/320 (5%)
Query: 17 EITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHL 76
++ +RY +G G +G+V ATDT + VAIKKI + RE+KLLK L
Sbjct: 6 KVADRYLKREVLGQGTYGVVFKATDTKNGETVAIKKIRLGKEKEGVNVTALREIKLLKEL 65
Query: 77 RHENLICLEDIFLSPLEDIYFVTELQGTDLHRLLQTRPL--EKQFVQYFLYQILRGLKYV 134
+H ++I L D F E+++ V E TDL +++ R L V+ +L IL+GL+Y
Sbjct: 66 KHPHIIELIDAFPHK-ENLHIVFEFMETDLEAVIRDRNLYLSPGDVKSYLQMILKGLEYC 124
Query: 135 HSAGVIHRDLKPSNILINENCDLKICDFGLARI---QDPQMTGYVSTRYYRAPEIMLTWQ 191
H V+HRD+KP+N+LI N LK+ DFGLARI + T V R+YRAPE++ +
Sbjct: 125 HGKWVLHRDMKPNNLLIGPNGQLKLADFGLARIFGSPGRKFTHQVFARWYRAPELLFGAK 184
Query: 192 KYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDV-IDTICSENTLK 250
+Y+ VD+W+AGCIFAE++ +P G + Q S I G+P D D IC + ++
Sbjct: 185 QYDGAVDVWAAGCIFAELLLRRPFLQGNSDIDQLSKIFAAFGTPKADQWPDMICLPDYVE 244
Query: 251 FVTSLPHRDPVP-FSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPYLSPYHDPTD 309
+ P P S + DA+DLL KM +DPK RI+ AL H Y + PTD
Sbjct: 245 Y-----QFVPAPSLRSLLPTVSEDALDLLSKMFTYDPKSRISIQQALKHRYFTSAPSPTD 299
Query: 310 E---PIAEAKFDWNFNDADL 326
P +K D +D+ L
Sbjct: 300 PLKLPRPVSKQDAKSSDSKL 319
>YBR160w [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 298
Score = 182 bits (462), Expect = 9e-46
Identities = 112/294 (38%), Positives = 158/294 (53%), Gaps = 13/294 (4%)
Query: 17 EITNRYTNLNPVGMGAFGLVCSATDTLTSQP---VAIKKIMKPFSTSVLAKRTYRELKLL 73
E+ N Y L VG G +G+V A D Q VA+KKI + RE+ LL
Sbjct: 4 ELAN-YKRLEKVGEGTYGVVYKALDLRPGQGQRVVALKKIRLESEDEGVPSTAIREISLL 62
Query: 74 KHLRHENLICLEDIFLSPLEDIYFVTELQGTDLHRLLQ----TRPLEKQFVQYFLYQILR 129
K L+ +N++ L DI S +Y V E DL R ++ +PL V+ F+ Q+ +
Sbjct: 63 KELKDDNIVRLYDIVHSDAHKLYLVFEFLDLDLKRYMEGIPKDQPLGADIVKKFMMQLCK 122
Query: 130 GLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQMTGY---VSTRYYRAPEI 186
G+ Y HS ++HRDLKP N+LIN++ +LK+ DFGLAR + Y + T +YRAPE+
Sbjct: 123 GIAYCHSHRILHRDLKPQNLLINKDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEV 182
Query: 187 MLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSE 246
+L ++Y+ VD WS GCIFAEM KP+F G + Q I +LG+P + + I
Sbjct: 183 LLGGKQYSTGVDTWSIGCIFAEMCNRKPIFSGDSEIDQIFKIFRVLGTPNEAIWPDIV-- 240
Query: 247 NTLKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPY 300
F S P S +L+P IDLL+K+L +DP RI+A A HPY
Sbjct: 241 YLPDFKPSFPQWRRKDLSQVVPSLDPRGIDLLDKLLAYDPINRISARRAAIHPY 294
>Hs20986508 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 277
Score = 181 bits (459), Expect = 2e-45
Identities = 104/256 (40%), Positives = 154/256 (59%), Gaps = 16/256 (6%)
Query: 100 ELQGTDLHRLLQTRPLEKQFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKI 159
EL +L +++Q L+ + + Y LYQ+L G+K++HSAG+IHRDLKPSNI++ +C LKI
Sbjct: 2 ELMDANLCQVIQME-LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKI 60
Query: 160 CDFGLARIQDP--QMTGYVSTRYYRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFP 217
DFGLAR MT YV TRYYRAPE++L Y VDIWS GCI EM+ K LFP
Sbjct: 61 LDFGLARTAGTSFMMTPYVVTRYYRAPEVIL-GMGYKENVDIWSVGCIMGEMVRHKILFP 119
Query: 218 GKDHVHQFSIITDLLGSPPKDVIDTI------CSENTLKFV-TSLPHRDP---VPFSSRF 267
G+D++ Q++ + + LG+P + + + EN K+ + P P P S
Sbjct: 120 GRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRNYVENRPKYAGLTFPKLFPDSLFPADSEH 179
Query: 268 QNLE-PDAIDLLEKMLVFDPKKRITAADALAHPYLSPYHDPTD-EPIAEAKFDWNFNDAD 325
L+ A DLL KMLV DP KRI+ DAL HPY++ ++DP + E +D ++ +
Sbjct: 180 NKLKASQARDLLSKMLVIDPAKRISVDDALQHPYINVWYDPAEVEAPPPQIYDKQLDERE 239
Query: 326 LPVDTWRVMMYSEILD 341
++ W+ ++Y E+++
Sbjct: 240 HTIEEWKELIYKEVMN 255
>At1g66750 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 348
Score = 181 bits (459), Expect = 2e-45
Identities = 108/296 (36%), Positives = 160/296 (53%), Gaps = 11/296 (3%)
Query: 20 NRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHE 79
+RY +G G +G+V ATDT T + VA+KKI + RE+KLLK L H
Sbjct: 11 DRYLRRQILGEGTYGVVYKATDTKTGKTVAVKKIRLGNQKEGVNFTALREIKLLKELNHP 70
Query: 80 NLICLEDIFLSPLEDIYFVTELQGTDLHRLLQTRP--LEKQFVQYFLYQILRGLKYVHSA 137
+++ L D F ++ V E TDL +++ R L ++ ++ L+GL Y H
Sbjct: 71 HIVELIDAFPHD-GSLHLVFEYMQTDLEAVIRDRNIFLSPGDIKSYMLMTLKGLAYCHKK 129
Query: 138 GVIHRDLKPSNILINENCDLKICDFGLARI---QDPQMTGYVSTRYYRAPEIMLTWQKYN 194
V+HRD+KP+N+LI EN LK+ DFGLAR+ + + T V +YRAPE++ ++Y
Sbjct: 130 WVLHRDMKPNNLLIGENGLLKLADFGLARLFGSPNRRFTHQVFATWYRAPELLFGSRQYG 189
Query: 195 VEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSP-PKDVIDTICSENTLKFVT 253
VD+W+AGCIFAE++ +P PG + Q I G+P P D I + ++F
Sbjct: 190 AGVDVWAAGCIFAELLLRRPFLPGSTEIDQLGKIFQAFGTPVPSQWSDMIYLPDYMEF-- 247
Query: 254 SLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPYLSPYHDPTD 309
+ P + F DA+DLL KM ++DP++RIT AL H Y S PT+
Sbjct: 248 --SYTPAPPLRTIFPMASDDALDLLAKMFIYDPRQRITIQQALDHRYFSSSPSPTE 301
>Hs16936528 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 298
Score = 181 bits (458), Expect = 3e-45
Identities = 111/292 (38%), Positives = 155/292 (53%), Gaps = 9/292 (3%)
Query: 22 YTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHENL 81
+ + +G G +G+V A + LT + VA+KKI T + RE+ LLK L H N+
Sbjct: 4 FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNI 63
Query: 82 ICLEDIFLSPLEDIYFVTELQGTDLHRLLQTRPLEK---QFVQYFLYQILRGLKYVHSAG 138
+ L D+ + +Y V E DL + + L ++ +L+Q+L+GL + HS
Sbjct: 64 VKLLDVIHTE-NKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHR 122
Query: 139 VIHRDLKPSNILINENCDLKICDFGLARIQDPQMTGY---VSTRYYRAPEIMLTWQKYNV 195
V+HRDLKP N+LIN +K+ DFGLAR + Y V T +YRAPEI+L + Y+
Sbjct: 123 VLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYST 182
Query: 196 EVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLKFVTSL 255
VDIWS GCIFAEM+ + LFPG + Q I LG+P + V + S K S
Sbjct: 183 AVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYK--PSF 240
Query: 256 PHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPYLSPYHDP 307
P FS L+ D LL +ML +DP KRI+A ALAHP+ P
Sbjct: 241 PKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKP 292
>CE26422 [D] KOG0600 Cdc2-related protein kinase
Length = 684
Score = 181 bits (458), Expect = 3e-45
Identities = 105/310 (33%), Positives = 167/310 (53%), Gaps = 23/310 (7%)
Query: 22 YTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHENL 81
YT L+ +G G +G V A + LT + VA+K++ RE+K+L+ L H+N+
Sbjct: 311 YTMLDQIGEGTYGQVYKAVNNLTGEQVALKRVRLENEKEGFPITAIREIKILRQLHHKNI 370
Query: 82 ICLEDIFLSPLE---------DIYFVTELQGTDLHRLLQTRPL---EKQFVQYFLYQILR 129
+ L DI + + + Y V E DL LL+++ L K + Q+L
Sbjct: 371 VRLMDIVIDDISMDELKRTRANFYLVFEYVDHDLIGLLESKELVDFNKDQICSLFKQLLE 430
Query: 130 GLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQM---TGYVSTRYYRAPEI 186
GL Y+H+ G +HRD+K SNIL+N +LKI D GLAR+ + + T V T +YR PE+
Sbjct: 431 GLAYIHNTGFLHRDIKCSNILVNNKGELKIADLGLARLWEKESRLYTNRVITLWYRPPEL 490
Query: 187 MLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKD---VIDTI 243
+L ++Y +D+WS GC+ E+ KPLF G + Q +I+ + GSP D + +
Sbjct: 491 LLGDERYGPAIDVWSTGCMLGELFTRKPLFNGNNEFGQLELISKVCGSPNVDNWPELTEL 550
Query: 244 CSENTLKFVTSLPHRDPVPFSSRFQNLEP-DAIDLLEKMLVFDPKKRITAADALAHPYLS 302
NT + + R F+++ P +A+DLL+KML +P+KRI+A +AL HP++
Sbjct: 551 VGWNTFRMKRTYQRR----IREEFEHIMPREAVDLLDKMLTLNPEKRISAKEALNHPWIR 606
Query: 303 PYHDPTDEPI 312
T +P+
Sbjct: 607 SLEHTTVQPL 616
>ECU08g1920 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 296
Score = 180 bits (457), Expect = 3e-45
Identities = 104/291 (35%), Positives = 159/291 (53%), Gaps = 12/291 (4%)
Query: 18 ITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLR 77
+T + L +G G +G+V A + T++ VA+KKI + T RE+ LLK+L+
Sbjct: 1 MTESFQKLEKIGEGTYGVVYKARERNTNRVVALKKIRLENENEGIPATTIREILLLKNLK 60
Query: 78 HENLICLEDIFLSPLEDIYFVTELQGTDLHRLL-----QTRPLEKQFVQYFLYQILRGLK 132
H ++ L D+ + +Y V E DL R L + R +E+ FV+ Q+L ++
Sbjct: 61 HSTIVELSDVIYNN-NKMYLVFEYVELDLRRYLDRMSDEGRLVEEGFVRKMSQQLLTAME 119
Query: 133 YVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQMTGY---VSTRYYRAPEIMLT 189
Y HS + HRDLKP NIL++ ++K+ DFGL R + Y V T +YR PE++L
Sbjct: 120 YCHSRNIFHRDLKPQNILVDPKENIKLADFGLGRAAGIPLRTYTTEVVTLWYRPPELLLG 179
Query: 190 WQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTL 249
+ Y+ VD+WSA CI AE++ +P FPG + Q I +LG+P + EN
Sbjct: 180 CKYYDASVDVWSAACIMAEVVLMRPFFPGDSEIDQLFRIFKVLGTPNNSRWSNV--ENFP 237
Query: 250 KFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPY 300
+ P DPV + F+ +PD +DL+ KML +DPK R+TA + L+H Y
Sbjct: 238 NYKVEFPVWDPVDLKTIFRG-DPDFVDLISKMLEYDPKMRMTAKNGLSHKY 287
>Hs20502986 [T] KOG0660 Mitogen-activated protein kinase
Length = 277
Score = 178 bits (451), Expect = 2e-44
Identities = 98/249 (39%), Positives = 144/249 (57%), Gaps = 28/249 (11%)
Query: 18 ITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLR 77
I RY +G GA+G+V A D T + VAIKKI F A+RT+RE+ LL+
Sbjct: 9 IVRRYLLRRQLGQGAYGIVWKAVDRRTGEVVAIKKIFDAFRDKTDAQRTFREITLLQEFG 68
Query: 78 -HENLICLEDIFLSPLE-DIYFVTELQG-----------------TDLHRLLQTRPL-EK 117
H N+I L D+ + + DIY V E G TDL+ +++ L +
Sbjct: 69 DHPNIISLLDVIRAENDRDIYLVFEFMGCPPSPPPPTAVRTLSADTDLNAVIRKGGLLQD 128
Query: 118 QFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARI--------QD 169
V+ YQ+LR +++HS V+HRD KPSN+L++ NC +K+CDFGLAR +D
Sbjct: 129 VHVRSIFYQLLRATRFLHSGHVVHRDQKPSNVLLDANCTVKLCDFGLARSLGDLPEGPED 188
Query: 170 PQMTGYVSTRYYRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIIT 229
+T YV+TR+YRAPE++L+ +Y + VD+WS GCI EM+ G+PLFPG +HQ +I
Sbjct: 189 QAVTEYVATRWYRAPEVLLSSHRYTLGVDMWSLGCILGEMLRGRPLFPGTSTLHQLELIL 248
Query: 230 DLLGSPPKD 238
+ + P ++
Sbjct: 249 ETIPPPSEE 257
>At1g57870 [G] KOG0658 Glycogen synthase kinase-3
Length = 420
Score = 177 bits (450), Expect = 2e-44
Identities = 112/306 (36%), Positives = 170/306 (54%), Gaps = 29/306 (9%)
Query: 19 TNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRH 78
T Y + VG G+FG+V A T + VAIKK+++ + REL++++ L H
Sbjct: 79 TVSYIAEHVVGTGSFGMVFQAKCRETGEVVAIKKVLQD------KRYKNRELQIMQMLDH 132
Query: 79 ENLICLEDIFLSPLED--------IYFVTEL---QGTDLHRLLQTRPLEKQFVQYFLYQI 127
N++CL+ F S E+ + FV E R+ Q PL +V+ + YQI
Sbjct: 133 PNVVCLKHSFYSRTENEEVYLNLVLEFVPETVNRTARSYSRMNQLMPLI--YVKLYTYQI 190
Query: 128 LRGLKYVHSA-GVIHRDLKPSNILINENC-DLKICDFGLARIQ---DPQMTGYVSTRYYR 182
RGL Y+H+ G+ HRD+KP N+L+N + LKICDFG A++ +P ++ Y+ +RYYR
Sbjct: 191 CRGLAYLHNCCGLCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNIS-YICSRYYR 249
Query: 183 APEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDT 242
APE++ +Y +DIWS GC+ AE++ G+PLFPG+ V Q I +LG+P ++ I
Sbjct: 250 APELIFGATEYTTAIDIWSTGCVMAELLLGQPLFPGESGVDQLVEIIKVLGTPTREEIKC 309
Query: 243 ICSENTLKFVTSLPHRDPVPFSSRFQ-NLEPDAIDLLEKMLVFDPKKRITAADALAHPYL 301
+ + N +F P P P+ FQ L P+A+DLL + + P R TA +A HP+
Sbjct: 310 M-NPNYTEF--KFPQIKPHPWHKVFQKRLPPEAVDLLCRFFQYSPNLRCTAVEACIHPFF 366
Query: 302 SPYHDP 307
DP
Sbjct: 367 DELRDP 372
>At1g18040 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 391
Score = 177 bits (448), Expect = 4e-44
Identities = 110/304 (36%), Positives = 158/304 (51%), Gaps = 21/304 (6%)
Query: 17 EITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHL 76
++ +RY +G G +G+V ATDT T Q VAIKKI + RE+K+LK L
Sbjct: 7 KVADRYLKQEVLGQGTYGVVFKATDTKTEQTVAIKKIRLGKQREGVNITALREIKMLKEL 66
Query: 77 RHENLICLEDIFLSPLEDIYFVTELQGTDLHRLLQTRP--LEKQFVQYFLYQILRGLKYV 134
+H ++I L D F E+++ V E TDL +++ L ++ +L +GL Y
Sbjct: 67 KHPHIILLIDAFPHK-ENLHLVFEFMETDLEAVIRDSNIFLSPADIKSYLLMTFKGLAYC 125
Query: 135 HSAGVIHRDLKPSNILINENCDLKICDFGLARI---QDPQMTGYVSTRYYRAPEIMLTWQ 191
H V+HRD+KP+N+LI + LK+ DFGLARI + + T V R+YRAPE++ +
Sbjct: 126 HDKWVLHRDMKPNNLLIGVDGQLKLADFGLARIFGSPNRKFTHQVFARWYRAPELLFGAK 185
Query: 192 KYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLKF 251
+Y VD+W+ CIFAE++ +P G + Q S I G+P D +
Sbjct: 186 QYGAAVDVWAVACIFAELLLRRPFLQGNSDIDQLSKIFAAFGTPKADQWPDL-------- 237
Query: 252 VTSLP-----HRDPVP-FSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPYLSPYH 305
T LP P P S F + DA+DLL KM +DPK RI+ AL H Y +
Sbjct: 238 -TKLPDYVEYQFVPAPSLRSLFPAVSDDALDLLSKMFTYDPKARISIKQALEHRYFTSAP 296
Query: 306 DPTD 309
PTD
Sbjct: 297 APTD 300
>7297578 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 822
Score = 177 bits (448), Expect = 4e-44
Identities = 109/286 (38%), Positives = 159/286 (55%), Gaps = 9/286 (3%)
Query: 20 NRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHE 79
NRY L +G G +G V T + VAIK++ + + + A RE+K LK L H
Sbjct: 2 NRYITLTQLGDGTYGTVVLGQRKDTGEKVAIKRMKRKYYSWEEAMNL-REVKSLKKLSHP 60
Query: 80 NLICLEDIFLSPLEDIYFVTELQGTDLHRLLQTRP--LEKQFVQYFLYQILRGLKYVHSA 137
N++ L+++ + + +YFV E +L+++++ R L + ++ L+Q+L GL ++H
Sbjct: 61 NIVKLKEV-IRENDTLYFVFEYMKENLYQMIKDRDTHLPEPELKSILFQVLTGLAFMHRH 119
Query: 138 GVIHRDLKPSNILINENCDLKICDFGLARI--QDPQMTGYVSTRYYRAPEIMLTWQKYNV 195
G HRDLKP N+L + +KI DFGLAR P T YVSTR+YRAPE++L Y
Sbjct: 120 GFFHRDLKPENLLCSGPDLIKIADFGLAREIRSRPPFTDYVSTRWYRAPEVLLHSTNYGS 179
Query: 196 EVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPK-DVIDTICSENTLKFVTS 254
+D+W+ GCI AE+ +PLFPG V Q I +LG+P K D D + + F
Sbjct: 180 TIDLWAMGCIMAELYTFRPLFPGSSEVDQLFKICSVLGTPDKDDWPDGYRLASMIHF--R 237
Query: 255 LPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPY 300
P VP SS + +DLLE ML +DP KR TA +L +PY
Sbjct: 238 YPDCIKVPLSSVVSRCSQNGLDLLEDMLAYDPDKRPTAQQSLKYPY 283
>7300773 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 302
Score = 176 bits (447), Expect = 5e-44
Identities = 110/300 (36%), Positives = 167/300 (55%), Gaps = 26/300 (8%)
Query: 20 NRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHE 79
+RY L +G G G V A D ++ VAIKK+ +A T RE+K L+ + E
Sbjct: 7 SRYKMLEKIGEGVHGCVFKAIDLQRNKEVAIKKVALKNKFGNIALNTLREIKTLQLCKSE 66
Query: 80 NLICLEDIFLSPLEDIYFVTELQGTDLHRLLQTR--PLEKQFVQYFLYQILRGLKYVHSA 137
++ + DI+ L + V E Q L+ L++ PL +Q V+ F +Q+ +G+ Y+H A
Sbjct: 67 YILDIIDIY-PDLTGLSLVLEYQPDTLYNRLKSEVNPLSRQQVRKFAHQMFKGIAYLHEA 125
Query: 138 GVIHRDLKPSNILINENCDLKICDFGLARIQDPQ-----MTGYVSTRYYRAPEIMLTWQK 192
G++HRD+KP+N+LI++ LKI DFGLAR+ P+ + VSTR+YRAPEI+ QK
Sbjct: 126 GLMHRDIKPANLLISDTDMLKIADFGLARLYFPEDESRLYSPQVSTRWYRAPEILFGSQK 185
Query: 193 YNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLKFV 252
Y VD+W+AGC+ AEM+ G PLF G + Q +II LGSP N +
Sbjct: 186 YGTGVDMWAAGCVVAEMLRGVPLFAGTTDIEQLAIIIRTLGSP---------RLNQWPEL 236
Query: 253 TSLPHRDPVPFSS----RFQNLEPDA-----IDLLEKMLVFDPKKRITAADALAHPYLSP 303
TSLP + F + + NL P I+L+ ++V++PK R+ A++ + L+P
Sbjct: 237 TSLPDYSKIRFPNSVGIHWDNLFPSCTHAVEINLVSNLVVYNPKNRLKASEVGSASSLTP 296
>Hs11496279 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 623
Score = 176 bits (445), Expect = 8e-44
Identities = 106/286 (37%), Positives = 161/286 (56%), Gaps = 9/286 (3%)
Query: 20 NRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHE 79
NRYT + +G G +G V + + VAIK++ + F S RE+K LK L H
Sbjct: 2 NRYTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFY-SWDECMNLREVKSLKKLNHA 60
Query: 80 NLICLEDIFLSPLEDIYFVTELQGTDLHRLLQTRP--LEKQFVQYFLYQILRGLKYVHSA 137
N+I L+++ + + +YF+ E +L++L++ R + ++ +YQIL+GL ++H
Sbjct: 61 NVIKLKEV-IRENDHLYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKH 119
Query: 138 GVIHRDLKPSNILINENCDLKICDFGLARI--QDPQMTGYVSTRYYRAPEIMLTWQKYNV 195
G HRD+KP N+L +KI DFGLAR P T YVSTR+YRAPE++L Y+
Sbjct: 120 GFFHRDMKPENLLCMGPELVKIADFGLARELRSQPPYTDYVSTRWYRAPEVLLRSSVYSS 179
Query: 196 EVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPK-DVIDTICSENTLKFVTS 254
+D+W+ G I AE+ +PLFPG V + I +LG+P K D + +++ F
Sbjct: 180 PIDVWAVGSIMAELYMLRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNF--R 237
Query: 255 LPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPY 300
P P+ + N +AI L+ +ML +DPKKR TA+ AL HPY
Sbjct: 238 FPQCVPINLKTLIPNASNEAIQLMTEMLNWDPKKRPTASQALKHPY 283
>Hs7705551 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 632
Score = 175 bits (444), Expect = 1e-43
Identities = 106/291 (36%), Positives = 159/291 (54%), Gaps = 9/291 (3%)
Query: 20 NRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHE 79
NRYT + +G G +G V + + +AIKK+ + F S RE+K LK L H
Sbjct: 2 NRYTTIRQLGDGTYGSVLLGRSIESGELIAIKKMKRKFY-SWEECMNQREVKSLKKLNHA 60
Query: 80 NLICLEDIFLSPLEDIYFVTELQGTDLHRLLQTRP--LEKQFVQYFLYQILRGLKYVHSA 137
N++ L+++ + + +YF+ E +L++L++ R + ++ +YQIL+GL ++H
Sbjct: 61 NVVKLKEV-IRENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKL 119
Query: 138 GVIHRDLKPSNILINENCDLKICDFGLARI--QDPQMTGYVSTRYYRAPEIMLTWQKYNV 195
G HRDLKP N+L +KI DFGLAR P T YVSTR+YRAPE++L Y+
Sbjct: 120 GFFHRDLKPENLLCMGPELVKIADFGLAREIRSKPPYTDYVSTRWYRAPEVLLRSTNYSS 179
Query: 196 EVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPK-DVIDTICSENTLKFVTS 254
+D+W+ GCI AE+ +PLFPG + I +LG+P K D + + + F
Sbjct: 180 PIDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNF--R 237
Query: 255 LPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPYLSPYH 305
P P + N +A+ LL ML +DPKKR TA+ AL +PY H
Sbjct: 238 WPQCVPNNLKTLIPNASSEAVQLLRDMLQWDPKKRPTASQALRYPYFQVGH 288
>Hs4826675 [UT] KOG0662 Cyclin-dependent kinase CDK5
Length = 292
Score = 175 bits (444), Expect = 1e-43
Identities = 109/300 (36%), Positives = 163/300 (54%), Gaps = 23/300 (7%)
Query: 21 RYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHEN 80
+Y L +G G +G V A + T + VA+K++ + RE+ LLK L+H+N
Sbjct: 3 KYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKN 62
Query: 81 LICLEDIFLSPLEDIYFVTELQGTDLHRLLQT--RPLEKQFVQYFLYQILRGLKYVHSAG 138
++ L D+ S + + V E DL + + L+ + V+ FL+Q+L+GL + HS
Sbjct: 63 IVRLHDVLHSD-KKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSRN 121
Query: 139 VIHRDLKPSNILINENCDLKICDFGLARIQDPQMTGY---VSTRYYRAPEIMLTWQKYNV 195
V+HRDLKP N+LIN N +LK+ DFGLAR + Y V T +YR P+++ + Y+
Sbjct: 122 VLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYST 181
Query: 196 EVDIWSAGCIFAEMIE-GKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLKFVTS 254
+D+WSAGCIFAE+ G+PLFPG D Q I LLG+P +E +T
Sbjct: 182 SIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTP---------TEEQWPSMTK 232
Query: 255 LPHRDPVPF---SSRFQNLEP----DAIDLLEKMLVFDPKKRITAADALAHPYLSPYHDP 307
LP P P ++ N+ P DLL+ +L +P +RI+A +AL HPY S + P
Sbjct: 233 LPDYKPYPMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFSDFCPP 292
>At2g38620 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 311
Score = 175 bits (444), Expect = 1e-43
Identities = 110/303 (36%), Positives = 159/303 (52%), Gaps = 26/303 (8%)
Query: 21 RYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHE- 79
+Y L VG G +G V A + T + VA+KK + RE+ LL+ L
Sbjct: 3 KYEKLEKVGEGTYGKVYKAMEKTTGKLVALKKTRLEMDEEGIPPTALREISLLQMLSQSI 62
Query: 80 ---NLICLEDIFLS--------PLEDIYFVTELQGTDLHRLLQT-------RPLEKQFVQ 121
L+C+E + S P ++Y V E TDL + + + RPLE VQ
Sbjct: 63 YIVRLLCVEHVIQSKDSTVSHSPKSNLYLVFEYLDTDLKKFIDSHRKGSNPRPLEASLVQ 122
Query: 122 YFLYQILRGLKYVHSAGVIHRDLKPSNILINENCD-LKICDFGLARIQDPQMTGY---VS 177
F++Q+ +G+ + HS GV+HRDLKP N+L++++ LKI D GL+R + Y +
Sbjct: 123 RFMFQLFKGVAHCHSHGVLHRDLKPQNLLLDKDKGILKIADLGLSRAFTVPLKAYTHEIV 182
Query: 178 TRYYRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPK 237
T +YRAPE++L Y+ VDIWS GCIFAEMI + LFPG Q I LLG+P +
Sbjct: 183 TLWYRAPEVLLGSTHYSTAVDIWSVGCIFAEMIRRQALFPGDSEFQQLLHIFRLLGTPTE 242
Query: 238 DVIDTICSENTLKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALA 297
+ + L+ P +P S +L P+ IDLL +ML ++P +RI+A AL
Sbjct: 243 QQWPGVMA---LRDWHVYPKWEPQDLSRAVPSLSPEGIDLLTQMLKYNPAERISAKAALD 299
Query: 298 HPY 300
HPY
Sbjct: 300 HPY 302
>SPBC11B10.09 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 297
Score = 175 bits (443), Expect = 1e-43
Identities = 109/297 (36%), Positives = 157/297 (52%), Gaps = 16/297 (5%)
Query: 22 YTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHEN- 80
Y + +G G +G+V A L+ + VA+KKI + + RE+ LLK + EN
Sbjct: 4 YQKVEKIGEGTYGVVYKARHKLSGRIVAMKKIRLEDESEGVPSTAIREISLLKEVNDENN 63
Query: 81 ---LICLEDIFLSPLEDIYFVTELQGTDLHRLLQ------TRPLEKQFVQYFLYQILRGL 131
+ L DI L +Y V E DL + + L+ + VQ F YQ++ G+
Sbjct: 64 RSNCVRLLDI-LHAESKLYLVFEFLDMDLKKYMDRISETGATSLDPRLVQKFTYQLVNGV 122
Query: 132 KYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQMTGY---VSTRYYRAPEIML 188
+ HS +IHRDLKP N+LI++ +LK+ DFGLAR + Y + T +YRAPE++L
Sbjct: 123 NFCHSRRIIHRDLKPQNLLIDKEGNLKLADFGLARSFGVPLRNYTHEIVTLWYRAPEVLL 182
Query: 189 TWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENT 248
+ Y+ VDIWS GCIFAEMI PLFPG + + I +LG+P ++V +
Sbjct: 183 GSRHYSTGVDIWSVGCIFAEMIRRSPLFPGDSEIDEIFKIFQVLGTPNEEVWPGVTLLQD 242
Query: 249 LKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPYLSPYH 305
K ++ P + N E DAI+LL MLV+DP RI+A AL YL +H
Sbjct: 243 YK--STFPRWKRMDLHKVVPNGEEDAIELLSAMLVYDPAHRISAKRALQQNYLRDFH 297
>Hs7662388 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 632
Score = 175 bits (443), Expect = 1e-43
Identities = 106/291 (36%), Positives = 159/291 (54%), Gaps = 9/291 (3%)
Query: 20 NRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHE 79
NRYT + +G G +G V + + +AIKK+ + F S RE+K LK L H
Sbjct: 2 NRYTTIRQLGDGTYGSVLLGRSIESGELIAIKKMKRKFY-SWEECMNLREVKSLKKLNHA 60
Query: 80 NLICLEDIFLSPLEDIYFVTELQGTDLHRLLQTRP--LEKQFVQYFLYQILRGLKYVHSA 137
N++ L+++ + + +YF+ E +L++L++ R + ++ +YQIL+GL ++H
Sbjct: 61 NVVKLKEV-IRENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKH 119
Query: 138 GVIHRDLKPSNILINENCDLKICDFGLARI--QDPQMTGYVSTRYYRAPEIMLTWQKYNV 195
G HRDLKP N+L +KI DFGLAR P T YVSTR+YRAPE++L Y+
Sbjct: 120 GFFHRDLKPENLLCMGPELVKIADFGLAREIRSKPPYTDYVSTRWYRAPEVLLRSTNYSS 179
Query: 196 EVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPK-DVIDTICSENTLKFVTS 254
+D+W+ GCI AE+ +PLFPG + I +LG+P K D + + + F
Sbjct: 180 PIDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNF--R 237
Query: 255 LPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPYLSPYH 305
P P + N +A+ LL ML +DPKKR TA+ AL +PY H
Sbjct: 238 WPQCVPNNLKTLIPNASSEAVQLLRDMLQWDPKKRPTASQALRYPYFQVGH 288
>SPAC1687.15 [G] KOG0658 Glycogen synthase kinase-3
Length = 387
Score = 174 bits (442), Expect = 2e-43
Identities = 104/301 (34%), Positives = 168/301 (55%), Gaps = 25/301 (8%)
Query: 22 YTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHENL 81
YT+ VG G+FG+V + AIK++++ + REL++++ ++H N+
Sbjct: 32 YTSSKVVGSGSFGVVMQVHLIESDSKAAIKRVLQD------KRFKNRELQIMRIMKHPNI 85
Query: 82 ICLEDIFLSP---LEDIYF--VTELQGTDLHRLLQTRPLEKQF-----VQYFLYQILRGL 131
+ L + + +++Y V E ++R + +K V+ ++YQ+LR L
Sbjct: 86 VDLIAYYYTTGDNSDEVYLNLVLEFMPETIYRASRLYTRQKLSMPMLEVKLYIYQLLRSL 145
Query: 132 KYVHSAGVIHRDLKPSNILIN-ENCDLKICDFGLARIQ---DPQMTGYVSTRYYRAPEIM 187
Y+H++G+ HRD+KP N+L++ EN LK+CDFG A+I +P ++ Y+ +RYYRAPE++
Sbjct: 146 AYIHASGICHRDIKPQNLLLDPENGILKLCDFGSAKILVAGEPNVS-YICSRYYRAPELI 204
Query: 188 LTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSEN 247
Y +DIWS GC+ AE++ G PLFPG+ + Q I +LG+P ++ I T+ N
Sbjct: 205 FGATDYTHAIDIWSTGCVMAELMLGHPLFPGESGIDQLVEIIKILGTPSREQIKTM---N 261
Query: 248 TLKFVTSLPHRDPVPFSSRFQNLEP-DAIDLLEKMLVFDPKKRITAADALAHPYLSPYHD 306
P P P S F P DA+DLL KML + P R+TAA+A+ HP+ D
Sbjct: 262 PNYMEHRFPQIRPQPLSRVFSRSVPLDALDLLSKMLQYTPTDRLTAAEAMCHPFFDELRD 321
Query: 307 P 307
P
Sbjct: 322 P 322
>At4g18710 [G] KOG0658 Glycogen synthase kinase-3
Length = 380
Score = 174 bits (442), Expect = 2e-43
Identities = 109/297 (36%), Positives = 165/297 (54%), Gaps = 29/297 (9%)
Query: 28 VGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTY--RELKLLKHLRHENLICLE 85
VG G+FG+V A T + VAIKK VL R Y REL+L++ + H N++CL+
Sbjct: 46 VGTGSFGIVFQAKCLETGETVAIKK--------VLQDRRYKNRELQLMRVMDHPNVVCLK 97
Query: 86 DIFLSPLED----IYFVTELQGTDLHRLLQTRPLEKQ-----FVQYFLYQILRGLKYVHS 136
F S + V E L+R+L+ Q +V+ ++YQI RGL Y+H+
Sbjct: 98 HCFFSTTSKDELFLNLVMEYVPESLYRVLKHYSSANQRMPLVYVKLYMYQIFRGLAYIHN 157
Query: 137 -AGVIHRDLKPSNILINE-NCDLKICDFGLAR--IQDPQMTGYVSTRYYRAPEIMLTWQK 192
AGV HRDLKP N+L++ +KICDFG A+ ++ Y+ +R+YRAPE++ +
Sbjct: 158 VAGVCHRDLKPQNLLVDPLTHQVKICDFGSAKQLVKGEANISYICSRFYRAPELIFGATE 217
Query: 193 YNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENT-LKF 251
Y +DIWSAGC+ AE++ G+PLFPG++ V Q I +LG+P ++ I + T +F
Sbjct: 218 YTTSIDIWSAGCVLAELLLGQPLFPGENAVDQLVEIIKVLGTPTREEIRCMNPHYTDFRF 277
Query: 252 VTSLPHRDPVPFSSRF-QNLEPDAIDLLEKMLVFDPKKRITAADALAHPYLSPYHDP 307
H P+ F + + P+AID ++L + P R TA +A AHP+ +P
Sbjct: 278 PQIKAH----PWHKIFHKRMPPEAIDFASRLLQYSPSLRCTALEACAHPFFDELREP 330
>Hs4505569 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 493
Score = 174 bits (441), Expect = 2e-43
Identities = 107/287 (37%), Positives = 160/287 (55%), Gaps = 10/287 (3%)
Query: 21 RYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHEN 80
+Y NL VG G++G+V + T + VAIKK ++ ++ K RE+KLLK LRHEN
Sbjct: 3 KYENLGLVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHEN 62
Query: 81 LICLEDIFLSPLEDIYFVTELQGTDLHRLLQTRP--LEKQFVQYFLYQILRGLKYVHSAG 138
L+ L ++ + Y V E + L+ P L+ Q VQ +L+QI+ G+ + HS
Sbjct: 63 LVNLLEV-CKKKKRWYLVFEFVDHTILDDLELFPNGLDYQVVQKYLFQIINGIGFCHSHN 121
Query: 139 VIHRDLKPSNILINENCDLKICDFGLARI---QDPQMTGYVSTRYYRAPEIMLTWQKYNV 195
+IHRD+KP NIL++++ +K+CDFG AR T YV+TR+YRAPE+++ KY
Sbjct: 122 IIHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVYTDYVATRWYRAPELLVGDVKYGK 181
Query: 196 EVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGS-PPKDVIDTICSENTLKFVTS 254
VD+W+ GC+ EM G+PLFPG + Q I LG+ P+ + ++N +
Sbjct: 182 AVDVWAIGCLVTEMFMGEPLFPGDSDIDQLYHIMMCLGNLIPRH--QELFNKNPVFAGVR 239
Query: 255 LPH-RDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPY 300
LP ++ P R+ L IDL +K L DP KR A+ L H +
Sbjct: 240 LPEIKEREPLERRYPKLSEVVIDLAKKCLHIDPDKRPFCAELLHHDF 286
>Hs4505649 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 523
Score = 173 bits (439), Expect = 4e-43
Identities = 103/284 (36%), Positives = 149/284 (52%), Gaps = 8/284 (2%)
Query: 22 YTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHENL 81
Y L +G G + V LT VA+K+I RE+ LLK L+H N+
Sbjct: 192 YIKLEKLGEGTYATVYKGRSKLTENLVALKEIRLEHEEGAPCT-AIREVSLLKDLKHANI 250
Query: 82 ICLEDIFLSPLEDIYFVTELQGTDLHRLLQT--RPLEKQFVQYFLYQILRGLKYVHSAGV 139
+ L DI + + + V E DL + + + V+ FLYQILRGL Y H V
Sbjct: 251 VTLHDIVHTD-KSLTLVFEYLDKDLKQYMDDCGNIMSMHNVKLFLYQILRGLAYCHRRKV 309
Query: 140 IHRDLKPSNILINENCDLKICDFGLARIQDPQMTGY---VSTRYYRAPEIMLTWQKYNVE 196
+HRDLKP N+LINE +LK+ DFGLAR + Y V T +YR P+++L +Y +
Sbjct: 310 LHRDLKPQNLLINEKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSSEYLTQ 369
Query: 197 VDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLKFVTSLP 256
+D+W GCIF EM G+PLFPG + +I LLG+P ++ I S K + P
Sbjct: 370 IDMWGVGCIFFEMASGRPLFPGSTVEDELHLIFRLLGTPSQETWPGISSNEEFKNY-NFP 428
Query: 257 HRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPY 300
P P + L+ + I+L+ K L ++ KKR++A +A+ H Y
Sbjct: 429 KYKPEPLINHAPRLDSEGIELIRKFLQYESKKRVSAEEAMKHVY 472
>At1g09840 [G] KOG0658 Glycogen synthase kinase-3
Length = 421
Score = 172 bits (437), Expect = 7e-43
Identities = 108/304 (35%), Positives = 170/304 (55%), Gaps = 25/304 (8%)
Query: 19 TNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRH 78
T Y + + VG G+FG+V A T + VAIKK+++ + REL++++ L H
Sbjct: 80 TVSYISEHVVGTGSFGMVFQAKCRETGEVVAIKKVLQD------KRYKNRELQIMQMLDH 133
Query: 79 ENLICLEDIFLSPL--EDIYF--VTELQGTDLHRLLQTRPLEKQ-----FVQYFLYQILR 129
N + L+ F S E++Y V E ++R+ ++ Q +V+ + YQI R
Sbjct: 134 PNAVALKHSFFSRTDNEEVYLNLVLEFVPETVNRVARSYSRTNQLMPLIYVKLYTYQICR 193
Query: 130 GLKYVHSA-GVIHRDLKPSNILINENC-DLKICDFGLARIQ---DPQMTGYVSTRYYRAP 184
L Y+H++ G+ HRD+KP N+L+N + LKICDFG A++ +P ++ Y+ +RYYRAP
Sbjct: 194 ALAYIHNSFGLCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNVS-YICSRYYRAP 252
Query: 185 EIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTIC 244
E++ +Y +DIWS GC+ AE++ G+PLFPG+ V Q I +LG+P ++ I +
Sbjct: 253 ELIFGASEYTTAIDIWSTGCVMAELLLGQPLFPGESGVDQLVEIIKVLGTPTREEIKCM- 311
Query: 245 SENTLKFVTSLPHRDPVPFSSRFQ-NLEPDAIDLLEKMLVFDPKKRITAADALAHPYLSP 303
+ N +F P P P+ FQ L P+A+DLL + + P R TA +A HP
Sbjct: 312 NPNYTEF--KFPQIKPHPWHKVFQKRLPPEAVDLLCRFFQYSPNLRCTALEACIHPLFDE 369
Query: 304 YHDP 307
DP
Sbjct: 370 LRDP 373
>SPBC18H10.15 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 398
Score = 172 bits (436), Expect = 9e-43
Identities = 109/298 (36%), Positives = 163/298 (54%), Gaps = 14/298 (4%)
Query: 22 YTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHENL 81
Y L + G++G+V D T+ VA+KKI + + RE++ L +RH+N+
Sbjct: 74 YEILEKIEEGSYGIVYRGLDKSTNTLVALKKIKFDPNGIGFPITSLREIESLSSIRHDNI 133
Query: 82 ICLEDIFLSP-LEDIYFVTELQGTDLHRLLQTRPLE--KQFVQYFLYQILRGLKYVHSAG 138
+ LE + + L+D+Y V E DL LL P + + V+ + Q+L ++H
Sbjct: 134 VELEKVVVGKDLKDVYLVMEFMEHDLKTLLDNMPEDFLQSEVKTLMLQLLAATAFMHHHW 193
Query: 139 VIHRDLKPSNILINENCDLKICDFGLAR-IQDPQ--MTGYVSTRYYRAPEIMLTWQKYNV 195
+HRDLKPSN+L+N ++K+ DFGLAR + +P+ +T V T +YRAPE++L Y
Sbjct: 194 YLHRDLKPSNLLMNNTGEIKLADFGLARPVSEPKSSLTRLVVTLWYRAPELLLGAPSYGK 253
Query: 196 EVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLKFVTSL 255
E+D+WS GCIFAEMI PLF GK + Q I +LLG P ++ L + +
Sbjct: 254 EIDMWSIGCIFAEMITRTPLFSGKSELDQLYKIFNLLGYPTREEWPQYF---LLPYANKI 310
Query: 256 PHRDPVPFSSRFQ----NLEPDAIDLLEKMLVFDPKKRITAADALAHPYLSPYHDPTD 309
H VP S+ + NL +A DLL ++L +P KRI+A +AL HPY P D
Sbjct: 311 KH-PTVPTHSKIRTSIPNLTGNAYDLLNRLLSLNPAKRISAKEALEHPYFYESPRPKD 367
>At3g05840 [G] KOG0658 Glycogen synthase kinase-3
Length = 409
Score = 172 bits (435), Expect = 1e-42
Identities = 106/297 (35%), Positives = 168/297 (55%), Gaps = 29/297 (9%)
Query: 28 VGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTY--RELKLLKHLRHENLICLE 85
VG G+FG+V A T + VAIKK VL R Y REL+ ++ L H N++ L+
Sbjct: 79 VGHGSFGVVFQAKCLETGETVAIKK--------VLQDRRYKNRELQTMRLLDHPNVVSLK 130
Query: 86 DIFLSPLE--DIYF--VTELQGTDLHRLLQ-----TRPLEKQFVQYFLYQILRGLKYVHS 136
F S E ++Y V E +HR+++ + + +V+ + YQI R L Y+H
Sbjct: 131 HCFFSTTEKDELYLNLVLEYVPETVHRVIKHYNKLNQRMPLVYVKLYTYQIFRSLSYIHR 190
Query: 137 A-GVIHRDLKPSNILINENC-DLKICDFGLARIQ---DPQMTGYVSTRYYRAPEIMLTWQ 191
GV HRD+KP N+L+N + +K+CDFG A++ +P ++ Y+ +RYYRAPE++
Sbjct: 191 CIGVCHRDIKPQNLLVNPHTHQVKLCDFGSAKVLVKGEPNIS-YICSRYYRAPELIFGAT 249
Query: 192 KYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLKF 251
+Y +D+WSAGC+ AE++ G+PLFPG+ V Q I +LG+P ++ I + + N +F
Sbjct: 250 EYTTAIDVWSAGCVLAELLLGQPLFPGESGVDQLVEIIKVLGTPTREEIKCM-NPNYTEF 308
Query: 252 VTSLPHRDPVPFSSRF-QNLEPDAIDLLEKMLVFDPKKRITAADALAHPYLSPYHDP 307
P P+ F + + P+A+DL+ ++L + P R A D+L HP+ DP
Sbjct: 309 --KFPQIKAHPWHKIFHKRMPPEAVDLVSRLLQYSPNLRCAALDSLVHPFFDELRDP 363
>Hs5453860 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 496
Score = 171 bits (434), Expect = 2e-42
Identities = 105/284 (36%), Positives = 147/284 (50%), Gaps = 8/284 (2%)
Query: 22 YTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHENL 81
Y L+ +G G + V LT VA+K+I RE+ LLK L+H N+
Sbjct: 165 YIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHEEGAPCT-AIREVSLLKDLKHANI 223
Query: 82 ICLEDIFLSPLEDIYFVTELQGTDLHRLLQT--RPLEKQFVQYFLYQILRGLKYVHSAGV 139
+ L DI + + + V E DL + L + V+ FL+Q+LRGL Y H V
Sbjct: 224 VTLHDIIHTE-KSLTLVFEYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQKV 282
Query: 140 IHRDLKPSNILINENCDLKICDFGLARIQDPQMTGY---VSTRYYRAPEIMLTWQKYNVE 196
+HRDLKP N+LINE +LK+ DFGLAR + Y V T +YR P+I+L Y+ +
Sbjct: 283 LHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQ 342
Query: 197 VDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLKFVTSLP 256
+D+W GCIF EM G+PLFPG Q I +LG+P ++ I S K + P
Sbjct: 343 IDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFK-TYNYP 401
Query: 257 HRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPY 300
S L+ D DLL K+L F+ + RI+A DA+ HP+
Sbjct: 402 KYRAEALLSHAPRLDSDGADLLTKLLQFEGRNRISAEDAMKHPF 445
>Hs15011928 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 448
Score = 171 bits (434), Expect = 2e-42
Identities = 105/284 (36%), Positives = 147/284 (50%), Gaps = 8/284 (2%)
Query: 22 YTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHENL 81
Y L+ +G G + V LT VA+K+I RE+ LLK L+H N+
Sbjct: 117 YIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHEEGAPCT-AIREVSLLKDLKHANI 175
Query: 82 ICLEDIFLSPLEDIYFVTELQGTDLHRLLQT--RPLEKQFVQYFLYQILRGLKYVHSAGV 139
+ L DI + + + V E DL + L + V+ FL+Q+LRGL Y H V
Sbjct: 176 VTLHDIIHTE-KSLTLVFEYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQKV 234
Query: 140 IHRDLKPSNILINENCDLKICDFGLARIQDPQMTGY---VSTRYYRAPEIMLTWQKYNVE 196
+HRDLKP N+LINE +LK+ DFGLAR + Y V T +YR P+I+L Y+ +
Sbjct: 235 LHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQ 294
Query: 197 VDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLKFVTSLP 256
+D+W GCIF EM G+PLFPG Q I +LG+P ++ I S K + P
Sbjct: 295 IDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFK-TYNYP 353
Query: 257 HRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPY 300
S L+ D DLL K+L F+ + RI+A DA+ HP+
Sbjct: 354 KYRAEALLSHAPRLDSDGADLLTKLLQFEGRNRISAEDAMKHPF 397
>At1g06390 [G] KOG0658 Glycogen synthase kinase-3
Length = 407
Score = 171 bits (433), Expect = 2e-42
Identities = 109/297 (36%), Positives = 167/297 (55%), Gaps = 29/297 (9%)
Query: 28 VGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTY--RELKLLKHLRHENLICLE 85
VG G+FG+V A T + VAIKK VL R Y REL+L++ + H N+I L+
Sbjct: 76 VGTGSFGIVFQAKCLETGESVAIKK--------VLQDRRYKNRELQLMRPMDHPNVISLK 127
Query: 86 DIFLSPLED----IYFVTELQGTDLHRLLQTRPLEKQ-----FVQYFLYQILRGLKYVHS 136
F S + V E L+R+L+ Q +V+ + YQI RGL Y+H+
Sbjct: 128 HCFFSTTSRDELFLNLVMEYVPETLYRVLRHYTSSNQRMPIFYVKLYTYQIFRGLAYIHT 187
Query: 137 A-GVIHRDLKPSNILINE-NCDLKICDFGLARIQ---DPQMTGYVSTRYYRAPEIMLTWQ 191
GV HRD+KP N+L++ +K+CDFG A++ +P ++ Y+ +RYYRAPE++
Sbjct: 188 VPGVCHRDVKPQNLLVDPLTHQVKLCDFGSAKVLVKGEPNIS-YICSRYYRAPELIFGAT 246
Query: 192 KYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLKF 251
+Y +DIWSAGC+ AE++ G+PLFPG++ V Q I +LG+P ++ I + + N F
Sbjct: 247 EYTASIDIWSAGCVLAELLLGQPLFPGENSVDQLVEIIKVLGTPTREEIRCM-NPNYTDF 305
Query: 252 VTSLPHRDPVPFSSRF-QNLEPDAIDLLEKMLVFDPKKRITAADALAHPYLSPYHDP 307
P P+ F + + P+AIDL ++L + P R TA +A AHP+ + +P
Sbjct: 306 --RFPQIKAHPWHKVFHKRMPPEAIDLASRLLQYSPSLRCTALEACAHPFFNELREP 360
>Hs4758652 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 358
Score = 171 bits (432), Expect = 3e-42
Identities = 101/297 (34%), Positives = 156/297 (52%), Gaps = 12/297 (4%)
Query: 21 RYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHEN 80
+Y + +G G++G+V + T Q VAIKK ++ V+ K RE+++LK L+H N
Sbjct: 4 KYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQLKHPN 63
Query: 81 LICLEDIFLSPLEDIYFVTELQGTDLHRLLQ-TRPLEKQFVQYFLYQILRGLKYVHSAGV 139
L+ L ++F T LH L + R + + V+ +Q L+ + + H
Sbjct: 64 LVNLLEVFRRKRRLHLVFEYCDHTVLHELDRYQRGVPEHLVKSITWQTLQAVNFCHKHNC 123
Query: 140 IHRDLKPSNILINENCDLKICDFGLARI---QDPQMTGYVSTRYYRAPEIMLTWQKYNVE 196
IHRD+KP NILI ++ +K+CDFG AR+ T YV+TR+YR+PE+++ +Y
Sbjct: 124 IHRDVKPENILITKHSVIKLCDFGFARLLTGPSDYYTDYVATRWYRSPELLVGDTQYGPP 183
Query: 197 VDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVI---DTICSENTLKFVT 253
VD+W+ GC+FAE++ G PL+PGK V Q +I LG D+I + S N
Sbjct: 184 VDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLG----DLIPRHQQVFSTNQYFSGV 239
Query: 254 SLPH-RDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPYLSPYHDPTD 309
+P D P +F N+ A+ LL+ L DP +R+T L HPY + D
Sbjct: 240 KIPDPEDMEPLELKFPNISYPALGLLKGCLHMDPTERLTCEQLLHHPYFENIREIED 296
>At5g26751 [G] KOG0658 Glycogen synthase kinase-3
Length = 413
Score = 171 bits (432), Expect = 3e-42
Identities = 106/297 (35%), Positives = 167/297 (55%), Gaps = 29/297 (9%)
Query: 28 VGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTY--RELKLLKHLRHENLICLE 85
VG G+FG+V A T + VAIKK VL R Y REL+ ++ L H N++ L+
Sbjct: 75 VGHGSFGVVFQAKCLETGETVAIKK--------VLQDRRYKNRELQTMRLLDHPNVVSLK 126
Query: 86 DIFLSPLE--DIYF--VTELQGTDLHRLLQ-----TRPLEKQFVQYFLYQILRGLKYVHS 136
F S E ++Y V E +HR+++ + + +V+ + YQI R L Y+H
Sbjct: 127 HCFFSTTEKDELYLNLVLEYVPETVHRVIKHYNKLNQRMPLIYVKLYTYQIFRALSYIHR 186
Query: 137 A-GVIHRDLKPSNILINENC-DLKICDFGLARIQ---DPQMTGYVSTRYYRAPEIMLTWQ 191
GV HRD+KP N+L+N + +K+CDFG A++ +P ++ Y+ +RYYRAPE++
Sbjct: 187 CIGVCHRDIKPQNLLVNPHTHQVKLCDFGSAKVLVKGEPNIS-YICSRYYRAPELIFGAT 245
Query: 192 KYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLKF 251
+Y +D+WSAGC+ AE++ G+PLFPG+ V Q I +LG+P ++ I + + N +F
Sbjct: 246 EYTTAIDVWSAGCVLAELLLGQPLFPGESGVDQLVEIIKVLGTPTREEIKCM-NPNYTEF 304
Query: 252 VTSLPHRDPVPFSSRF-QNLEPDAIDLLEKMLVFDPKKRITAADALAHPYLSPYHDP 307
P P+ F + + P+A+DL+ ++L + P R A D L HP+ DP
Sbjct: 305 --KFPQIKAHPWHKIFHKRMPPEAVDLVSRLLQYSPNLRSAALDTLVHPFFDELRDP 359
>CE29073 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 700
Score = 170 bits (431), Expect = 3e-42
Identities = 101/285 (35%), Positives = 152/285 (52%), Gaps = 8/285 (2%)
Query: 22 YTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHENL 81
Y L+ +G G + V LT++ VA+K+I RE+ LL++LRH N+
Sbjct: 361 YEKLDKLGEGTYATVFRGRSILTNKFVALKEIRLEQEEGAPCT-AIREVSLLRNLRHANV 419
Query: 82 ICLEDIFLSPLEDIYFVTELQGTDLHRLLQT--RPLEKQFVQYFLYQILRGLKYVHSAGV 139
+ L DI + + V E DL + + + ++ ++ FLYQ+LRGL Y H V
Sbjct: 420 VTLHDIIHTD-RLLTLVFEYVDRDLKQYMDSCNNAMQMNNIRLFLYQLLRGLAYCHQRRV 478
Query: 140 IHRDLKPSNILINENCDLKICDFGLARIQDPQMTGY---VSTRYYRAPEIMLTWQKYNVE 196
+HRDLKP N+LI +LK+ DFGLAR + Y V T +YR P+++L Y+
Sbjct: 479 LHRDLKPQNLLITAKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTDYSTH 538
Query: 197 VDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLKFVTSLP 256
+D+W GCI EMI G+ LFPG Q +I LGSP D TIC + T + +
Sbjct: 539 IDMWGVGCILFEMIAGRALFPGGTPTEQLGLIFRTLGSPRPDRHPTICEKPTF-YPYANR 597
Query: 257 HRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPYL 301
H +P P + ++ +LL K L ++ K R++AA+A+ HP+L
Sbjct: 598 HYNPDPLCRQIPRIDAHGFELLMKFLQYEGKDRVSAAEAVKHPFL 642
>CE06779 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 577
Score = 170 bits (431), Expect = 3e-42
Identities = 101/285 (35%), Positives = 152/285 (52%), Gaps = 8/285 (2%)
Query: 22 YTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHENL 81
Y L+ +G G + V LT++ VA+K+I RE+ LL++LRH N+
Sbjct: 238 YEKLDKLGEGTYATVFRGRSILTNKFVALKEIRLEQEEGAPCT-AIREVSLLRNLRHANV 296
Query: 82 ICLEDIFLSPLEDIYFVTELQGTDLHRLLQT--RPLEKQFVQYFLYQILRGLKYVHSAGV 139
+ L DI + + V E DL + + + ++ ++ FLYQ+LRGL Y H V
Sbjct: 297 VTLHDIIHTD-RLLTLVFEYVDRDLKQYMDSCNNAMQMNNIRLFLYQLLRGLAYCHQRRV 355
Query: 140 IHRDLKPSNILINENCDLKICDFGLARIQDPQMTGY---VSTRYYRAPEIMLTWQKYNVE 196
+HRDLKP N+LI +LK+ DFGLAR + Y V T +YR P+++L Y+
Sbjct: 356 LHRDLKPQNLLITAKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTDYSTH 415
Query: 197 VDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLKFVTSLP 256
+D+W GCI EMI G+ LFPG Q +I LGSP D TIC + T + +
Sbjct: 416 IDMWGVGCILFEMIAGRALFPGGTPTEQLGLIFRTLGSPRPDRHPTICEKPTF-YPYANR 474
Query: 257 HRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPYL 301
H +P P + ++ +LL K L ++ K R++AA+A+ HP+L
Sbjct: 475 HYNPDPLCRQIPRIDAHGFELLMKFLQYEGKDRVSAAEAVKHPFL 519
>At5g50860 [D] KOG0600 Cdc2-related protein kinase
Length = 580
Score = 170 bits (430), Expect = 4e-42
Identities = 107/295 (36%), Positives = 153/295 (51%), Gaps = 9/295 (3%)
Query: 22 YTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHENL 81
Y L +G G + V A D L+ + VA+KK+ + K RE+ +L+ L H N+
Sbjct: 114 YEKLEKIGQGTYSNVYKAKDLLSGKIVALKKVRFDNLEAESVKFMAREILVLRRLNHPNV 173
Query: 82 ICLEDIFLSPLE-DIYFVTELQGTDLHRLLQTRPLEKQF--VQYFLYQILRGLKYVHSAG 138
I L+ + S + +Y V E DL L T+ L+ V+ F+ Q+L GL++ HS G
Sbjct: 174 IKLQGLVTSRVSCSLYLVFEYMEHDLSGLAATQGLKFDLPQVKCFMKQLLSGLEHCHSRG 233
Query: 139 VIHRDLKPSNILINENCDLKICDFGLARIQDPQ----MTGYVSTRYYRAPEIMLTWQKYN 194
V+HRD+K SN+LI+ + LKI DFGLA DP+ MT V T +YR PE++L Y
Sbjct: 234 VLHRDIKGSNLLIDNDGILKIADFGLATFYDPKQKQTMTSRVVTLWYRPPELLLGATSYG 293
Query: 195 VEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLKFVTS 254
VD+WSAGCI AE++ GKP+ PG+ V Q I L GSP N F
Sbjct: 294 TGVDLWSAGCIMAELLAGKPVMPGRTEVEQLHKIFKLCGSPSDSYWKKYRLPNATLFKPQ 353
Query: 255 LPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPYLSPYHDPTD 309
P++ V + F P ++ L+E +L DP R T+ AL + + P D
Sbjct: 354 HPYKRCV--AEAFNGFTPSSVHLVETLLTIDPADRGTSTSALNSEFFTTEPLPCD 406
>At2g30980 [G] KOG0658 Glycogen synthase kinase-3
Length = 412
Score = 170 bits (430), Expect = 4e-42
Identities = 108/296 (36%), Positives = 167/296 (55%), Gaps = 27/296 (9%)
Query: 28 VGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTY--RELKLLKHLRHENLICLE 85
VG G+FG+V A T + VAIKK VL R Y REL+L++ + H N++ L+
Sbjct: 78 VGTGSFGIVFQAKCLETGESVAIKK--------VLQDRRYKNRELQLMRLMDHPNVVSLK 129
Query: 86 DIFLSPL--EDIYF--VTELQGTDLHRLLQTRPLEKQ-----FVQYFLYQILRGLKYVHS 136
F S ++++ V E L+R+L+ Q +V+ + YQI RGL Y+H+
Sbjct: 130 HCFFSTTTRDELFLNLVMEYVPETLYRVLKHYTSSNQRMPIFYVKLYTYQIFRGLAYIHT 189
Query: 137 A-GVIHRDLKPSNILINE-NCDLKICDFGLARI--QDPQMTGYVSTRYYRAPEIMLTWQK 192
A GV HRD+KP N+L++ K+CDFG A++ + Y+ +RYYRAPE++ +
Sbjct: 190 APGVCHRDVKPQNLLVDPLTHQCKLCDFGSAKVLVKGEANISYICSRYYRAPELIFGATE 249
Query: 193 YNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLKFV 252
Y +DIWSAGC+ AE++ G+PLFPG++ V Q I +LG+P ++ I + + N F
Sbjct: 250 YTSSIDIWSAGCVLAELLLGQPLFPGENSVDQLVEIIKVLGTPTREEIRCM-NPNYTDF- 307
Query: 253 TSLPHRDPVPFSSRF-QNLEPDAIDLLEKMLVFDPKKRITAADALAHPYLSPYHDP 307
P P+ F + + P+AIDL ++L + P R TA +A AHP+ + +P
Sbjct: 308 -RFPQIKAHPWHKVFHKRMPPEAIDLASRLLQYSPSLRCTALEACAHPFFNELREP 362
>Hs21040235 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 384
Score = 169 bits (429), Expect = 6e-42
Identities = 112/304 (36%), Positives = 161/304 (52%), Gaps = 29/304 (9%)
Query: 16 FEITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKH 75
F + Y NL +G G++ V + Q VA+K I V RE LLK
Sbjct: 46 FGAASSYLNLEKLGEGSYATVYKGISRINGQLVALKVISMNAEEGV-PFTAIREASLLKG 104
Query: 76 LRHENLICLEDIFLSPLEDIYFVTELQGTDLHRLLQTRP--LEKQFVQYFLYQILRGLKY 133
L+H N++ L DI + E + FV E TDL + + P L V+ F++Q+LRGL Y
Sbjct: 105 LKHANIVLLHDI-IHTKETLTFVFEYMHTDLAQYMSQHPGGLHPHNVRLFMFQLLRGLAY 163
Query: 134 VHSAGVIHRDLKPSNILINENCDLKICDFGLAR---IQDPQMTGYVSTRYYRAPEIMLTW 190
+H V+HRDLKP N+LI+ +LK+ DFGLAR I + V T +YR P+ +L
Sbjct: 164 IHHQHVLHRDLKPQNLLISHLGELKLADFGLARAKSIPSQTYSSEVVTLWYRPPDALLGA 223
Query: 191 QKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHV-HQFSIITDLLGSPPKDVIDTICSENTL 249
+Y+ E+DIW AGCIF EM +G+PLFPG ++ Q I ++LG P +E+T
Sbjct: 224 TEYSSELDIWGAGCIFIEMFQGQPLFPGVSNILEQLEKIWEVLGVP---------TEDTW 274
Query: 250 KFVTSLPHRDPVPFS-----------SRFQNLEPDAIDLLEKMLVFDPKKRITAADALAH 298
V+ LP+ +P F +R + P+A DL +ML P+ R++A +AL H
Sbjct: 275 PGVSKLPNYNPEWFPLPTPRSLHVVWNRLGRV-PEAEDLASQMLKGFPRDRVSAQEALVH 333
Query: 299 PYLS 302
Y S
Sbjct: 334 DYFS 337
>YPL031c [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 305
Score = 169 bits (427), Expect = 1e-41
Identities = 100/302 (33%), Positives = 162/302 (53%), Gaps = 19/302 (6%)
Query: 19 TNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRH 78
++++ L +G G + V + T VA+K++ K S RE+ L+K L+H
Sbjct: 4 SSQFKQLEKLGNGTYATVYKGLNKTTGVYVALKEV-KLDSEEGTPSTAIREISLMKELKH 62
Query: 79 ENLICLEDIFLSPLEDIYFVTELQGTDLHRLLQTRP-------LEKQFVQYFLYQILRGL 131
EN++ L D+ + + V E DL + + +R LE V+YF +Q+L+GL
Sbjct: 63 ENIVRLYDVIHTE-NKLTLVFEFMDNDLKKYMDSRTVGNTPRGLELNLVKYFQWQLLQGL 121
Query: 132 KYVHSAGVIHRDLKPSNILINENCDLKICDFGLAR---IQDPQMTGYVSTRYYRAPEIML 188
+ H ++HRDLKP N+LIN+ LK+ DFGLAR I + V T +YRAP++++
Sbjct: 122 AFCHENKILHRDLKPQNLLINKRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLM 181
Query: 189 TWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENT 248
+ Y+ +DIWS GCI AEMI GKPLFPG + Q +I D++G+P + + ++
Sbjct: 182 GSRTYSTSIDIWSCGCILAEMITGKPLFPGTNDEEQLKLIFDIMGTPNESLWPSV--TKL 239
Query: 249 LKFVTSLPHRDPVPFSSRFQ-----NLEPDAIDLLEKMLVFDPKKRITAADALAHPYLSP 303
K+ ++ R P Q L+ + +D L +L +P R++A AL HP+ +
Sbjct: 240 PKYNPNIQQRPPRDLRQVLQPHTKEPLDGNLMDFLHGLLQLNPDMRLSAKQALHHPWFAE 299
Query: 304 YH 305
Y+
Sbjct: 300 YY 301
>SPAC2F3.15 [D] KOG0600 Cdc2-related protein kinase
Length = 593
Score = 169 bits (427), Expect = 1e-41
Identities = 102/296 (34%), Positives = 154/296 (51%), Gaps = 8/296 (2%)
Query: 22 YTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHENL 81
Y ++ +G G +G V A +T+T VA+K+I T RE+K+L+ LRH+N+
Sbjct: 277 YEKIDQIGEGTYGKVYKAINTVTGDLVALKRIRLEQEKDGFPITTVREVKILQRLRHKNI 336
Query: 82 ICLEDIFLSPLEDIYFVTELQGTDLHRLLQTRPLE--KQFVQYFLYQILRGLKYVHSAGV 139
+ L +I + +Y V E DL +L L +++ QI L Y+H GV
Sbjct: 337 VRLLEIMVEK-SSVYMVFEYMDHDLTGVLLNSQLHFTPGNIKHLSKQIFEALAYLHHRGV 395
Query: 140 IHRDLKPSNILINENCDLKICDFGLARI----QDPQMTGYVSTRYYRAPEIMLTWQKYNV 195
+HRD+K SNIL+N N DLK DFGLAR + T V T ++R PE++L Y+
Sbjct: 396 LHRDIKGSNILLNNNGDLKFADFGLARFNTSSKSANYTNRVITLWFRPPELLLGETAYDT 455
Query: 196 EVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLKFVTSL 255
VDIWSAGCI E+ GKP F G+D + Q +I D++G+P + + + + +
Sbjct: 456 AVDIWSAGCIVMELFTGKPFFQGRDEISQLEVIYDMMGTPDVHSWPEVKNLPWYELLKPV 515
Query: 256 PHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPYLSPYHDPTDEP 311
+ + + L P AIDL +K+L +P R +A + L H Y + P EP
Sbjct: 516 EEKKSRFVETFKEILSPAAIDLCQKLLALNPFCRPSAHETLMHEYFTS-ESPPPEP 570
>At5g10270 [D] KOG0600 Cdc2-related protein kinase
Length = 505
Score = 169 bits (427), Expect = 1e-41
Identities = 112/303 (36%), Positives = 154/303 (49%), Gaps = 28/303 (9%)
Query: 22 YTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHENL 81
+ L +G G +G V A + T + VA+KKI RE+K+LK L HEN+
Sbjct: 26 FEKLEQIGEGTYGQVYMAKEIKTGEIVALKKIRMDNEREGFPITAIREIKILKKLHHENV 85
Query: 82 ICLEDIFLSPLED---------------IYFVTELQGTDLHRLLQTRPLEKQFVQYFLY- 125
I L++I SP D IY V E DL L L Q Y
Sbjct: 86 IQLKEIVTSPGRDRDDQGKPDNNKYKGGIYMVFEYMDHDLTGLADRPGLRFTVPQIKCYM 145
Query: 126 -QILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQMTGYVSTR----Y 180
Q+L GL Y H V+HRD+K SN+LI+ +LK+ DFGLAR TG ++ R +
Sbjct: 146 KQLLTGLHYCHVNQVLHRDIKGSNLLIDNEGNLKLADFGLARSYSHDHTGNLTNRVITLW 205
Query: 181 YRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDV- 239
YR PE++L KY +D+WS GCIFAE++ KP+ PGK+ Q + I +L GSP + +
Sbjct: 206 YRPPELLLGATKYGPAIDMWSVGCIFAELLHAKPILPGKNEQEQLNKIFELCGSPDEKLW 265
Query: 240 --IDTICSENTLKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALA 297
+ + N K L R F++ + A++LLEKMLV DP +RI+A DAL
Sbjct: 266 PGVSKMPWFNNFKPARPLKRR----VREFFRHFDRHALELLEKMLVLDPAQRISAKDALD 321
Query: 298 HPY 300
Y
Sbjct: 322 AEY 324
>Hs4502731 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 360
Score = 168 bits (426), Expect = 1e-41
Identities = 102/285 (35%), Positives = 155/285 (53%), Gaps = 7/285 (2%)
Query: 22 YTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHENL 81
+ LN +G G +G+V A DT T + VA+KK+ + + RE+ LL LRH N+
Sbjct: 39 FEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLRLRHPNI 98
Query: 82 ICLEDIFL-SPLEDIYFVTELQGTDLHRLLQTRP--LEKQFVQYFLYQILRGLKYVHSAG 138
+ L+++ + + LE I+ V DL LL+ P + V+ + Q+LRGL+Y+H
Sbjct: 99 VELKEVVVGNHLESIFLVMGYCEQDLASLLENMPTPFSEAQVKCIVLQVLRGLQYLHRNF 158
Query: 139 VIHRDLKPSNILINENCDLKICDFGLAR---IQDPQMTGYVSTRYYRAPEIMLTWQKYNV 195
+IHRDLK SN+L+ + +K DFGLAR + MT V T +YRAPE++L
Sbjct: 159 IIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPMTPKVVTLWYRAPELLLGTTTQTT 218
Query: 196 EVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLKFVTSL 255
+D+W+ GCI AE++ +PL PG +HQ +I LLG+P +++ S+ L SL
Sbjct: 219 SIDMWAVGCILAELLAHRPLLPGTSEIHQIDLIVQLLGTPSENIWPGF-SKLPLVGQYSL 277
Query: 256 PHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPY 300
+ +F L + LL + ++DPKKR TA D L Y
Sbjct: 278 RKQPYNNLKHKFPWLSEAGLRLLHFLFMYDPKKRATAGDCLESSY 322
>Hs16950647 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 314
Score = 168 bits (426), Expect = 1e-41
Identities = 102/285 (35%), Positives = 155/285 (53%), Gaps = 7/285 (2%)
Query: 22 YTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHENL 81
+ LN +G G +G+V A DT T + VA+KK+ + + RE+ LL LRH N+
Sbjct: 10 FEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLRLRHPNI 69
Query: 82 ICLEDIFL-SPLEDIYFVTELQGTDLHRLLQTRP--LEKQFVQYFLYQILRGLKYVHSAG 138
+ L+++ + + LE I+ V DL LL+ P + V+ + Q+LRGL+Y+H
Sbjct: 70 VELKEVVVGNHLESIFLVMGYCEQDLASLLENMPTPFSEAQVKCIVLQVLRGLQYLHRNF 129
Query: 139 VIHRDLKPSNILINENCDLKICDFGLAR---IQDPQMTGYVSTRYYRAPEIMLTWQKYNV 195
+IHRDLK SN+L+ + +K DFGLAR + MT V T +YRAPE++L
Sbjct: 130 IIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPMTPKVVTLWYRAPELLLGTTTQTT 189
Query: 196 EVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLKFVTSL 255
+D+W+ GCI AE++ +PL PG +HQ +I LLG+P +++ S+ L SL
Sbjct: 190 SIDMWAVGCILAELLAHRPLLPGTSEIHQIDLIVQLLGTPSENIWPGF-SKLPLVGQYSL 248
Query: 256 PHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPY 300
+ +F L + LL + ++DPKKR TA D L Y
Sbjct: 249 RKQPYNNLKHKFPWLSEAGLRLLHFLFMYDPKKRATAGDCLESSY 293
>YMR139w [G] KOG0658 Glycogen synthase kinase-3
Length = 370
Score = 168 bits (425), Expect = 2e-41
Identities = 98/286 (34%), Positives = 157/286 (54%), Gaps = 22/286 (7%)
Query: 28 VGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHENLICLEDI 87
VG G+FG+V + T++ VAIKK+++ + REL+++K L H N+I L+
Sbjct: 45 VGHGSFGVVFATVIQETNEKVAIKKVLQD------KRFKNRELEIMKMLSHINIIDLKYF 98
Query: 88 FLS--PLEDIYF--VTELQGTDLHRLL-----QTRPLEKQFVQYFLYQILRGLKYVHS-A 137
F ++IY + E L++ L Q P+ + ++Y+++Q+ + L Y+H A
Sbjct: 99 FYERDSQDEIYLNLILEYMPQSLYQRLRHFVHQRTPMSRLEIKYYMFQLFKSLNYLHHFA 158
Query: 138 GVIHRDLKPSNILIN-ENCDLKICDFGLARIQDPQM--TGYVSTRYYRAPEIMLTWQKYN 194
V HRD+KP N+L++ E LK+CDFG A+ P Y+ +RYYRAPE++ Y
Sbjct: 159 NVCHRDIKPQNLLVDPETWSLKLCDFGSAKQLKPTEPNVSYICSRYYRAPELIFGATNYT 218
Query: 195 VEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLKFVTS 254
++DIWS+GC+ AE++ G+P+FPG+ + Q I +LG+P K ICS N
Sbjct: 219 NQIDIWSSGCVMAELLLGQPMFPGESGIDQLVEIIKILGTPSK---QEICSMNPNYMEHK 275
Query: 255 LPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPY 300
P P+P S F+ + ++ L +L +DP +R A L PY
Sbjct: 276 FPQIKPIPLSRVFKKEDDQTVEFLADVLKYDPLERFNALQCLCSPY 321
>At5g64960 [D] KOG0600 Cdc2-related protein kinase
Length = 513
Score = 168 bits (425), Expect = 2e-41
Identities = 112/303 (36%), Positives = 153/303 (49%), Gaps = 28/303 (9%)
Query: 22 YTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHENL 81
+ L +G G +G V A + T + VA+KKI RE+K+LK L HEN+
Sbjct: 26 FEKLEQIGEGTYGQVYMAKEIKTGEIVALKKIRMDNEREGFPITAIREIKILKKLHHENV 85
Query: 82 ICLEDIFLSPLED---------------IYFVTELQGTDLHRLLQTRPLEKQFVQYFLY- 125
I L++I SP D IY V E DL L L Q Y
Sbjct: 86 IHLKEIVTSPGRDRDDQGKPDNNKYKGGIYMVFEYMDHDLTGLADRPGLRFTVPQIKCYM 145
Query: 126 -QILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQMTGYVSTR----Y 180
Q+L GL Y H V+HRD+K SN+LI+ +LK+ DFGLAR TG ++ R +
Sbjct: 146 KQLLTGLHYCHVNQVLHRDIKGSNLLIDNEGNLKLADFGLARSYSHDHTGNLTNRVITLW 205
Query: 181 YRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKD-- 238
YR PE++L KY +D+WS GCIFAE++ GKP+ PGK Q + I +L GSP +
Sbjct: 206 YRPPELLLGATKYGPAIDMWSVGCIFAELLNGKPILPGKTENEQLNKIYELCGSPDESNW 265
Query: 239 -VIDTICSENTLKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALA 297
+ + N +K L R +++ + A++LLEKMLV DP +RI A DAL
Sbjct: 266 PGVSKMPWYNQMKSSRPLKRR----VREIYRHFDRHALELLEKMLVLDPSQRICAKDALD 321
Query: 298 HPY 300
Y
Sbjct: 322 AEY 324
>At1g03740 [D] KOG0600 Cdc2-related protein kinase
Length = 542
Score = 168 bits (425), Expect = 2e-41
Identities = 108/302 (35%), Positives = 160/302 (52%), Gaps = 12/302 (3%)
Query: 20 NRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHE 79
N + L +G G + V A D L ++ VA+KK+ + K RE+ +++ L H
Sbjct: 211 NTFEKLEKIGQGTYSSVYRARDLLHNKIVALKKVRFDLNDMESVKFMAREIIVMRRLDHP 270
Query: 80 NLICLEDIFLSPLED-IYFVTELQGTDLHRL--LQTRPLEKQFVQYFLYQILRGLKYVHS 136
N++ LE + +P+ +Y V E DL L L + V+ ++ Q+L GL++ HS
Sbjct: 271 NVLKLEGLITAPVSSSLYLVFEYMDHDLLGLSSLPGVKFTEPQVKCYMRQLLSGLEHCHS 330
Query: 137 AGVIHRDLKPSNILINENCDLKICDFGLARIQDP----QMTGYVSTRYYRAPEIMLTWQK 192
GV+HRD+K SN+LI+ LKI DFGLA DP +T +V T +YR PE++L
Sbjct: 331 RGVLHRDIKGSNLLIDSKGVLKIADFGLATFFDPAKSVSLTSHVVTLWYRPPELLLGASH 390
Query: 193 YNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLKFV 252
Y V VD+WS GCI E+ GKP+ PGK V Q I L GSP ++ ++ F
Sbjct: 391 YGVGVDLWSTGCILGELYAGKPILPGKTEVEQLHKIFKLCGSPTENYWRKQKLPSSAGFK 450
Query: 253 TSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPYL--SPYH-DPTD 309
T++P+R V S F++ + LLE +L DP R +A AL Y P+ DP++
Sbjct: 451 TAIPYRRKV--SEMFKDFPASVLSLLETLLSIDPDHRSSADRALESEYFKTKPFACDPSN 508
Query: 310 EP 311
P
Sbjct: 509 LP 510
>Hs4502735 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 303
Score = 167 bits (423), Expect = 3e-41
Identities = 115/298 (38%), Positives = 152/298 (50%), Gaps = 20/298 (6%)
Query: 19 TNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSV---LAKRTYRELKLLKH 75
T+RY + +G+GA+G V A D + VA+K + P L T RE+ LL+
Sbjct: 3 TSRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGGGGGLPISTVREVALLRR 62
Query: 76 LR---HENLICLEDIFLSPLED----IYFVTELQGTDLHRLLQTRP---LEKQFVQYFLY 125
L H N++ L D+ + D + V E DL L P L + ++ +
Sbjct: 63 LEAFEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDLMR 122
Query: 126 QILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQM--TGYVSTRYYRA 183
Q LRGL ++H+ ++HRDLKP NIL+ +K+ DFGLARI QM T V T +YRA
Sbjct: 123 QFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMALTPVVVTLWYRA 182
Query: 184 PEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTI 243
PE++L Y VD+WS GCIFAEM KPLF G Q I DL+G PP+D
Sbjct: 183 PEVLLQ-STYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWPRD 241
Query: 244 CSENTLKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPYL 301
S F P R P P S +E LL +ML F+P KRI+A AL H YL
Sbjct: 242 VSLPRGAF----PPRGPRPVQSVVPEMEESGAQLLLEMLTFNPHKRISAFRALQHSYL 295
>At4g13020 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 443
Score = 167 bits (423), Expect = 3e-41
Identities = 107/299 (35%), Positives = 161/299 (53%), Gaps = 19/299 (6%)
Query: 21 RYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHEN 80
RY L +G G G V A + T + VA+KK+ + F RE+K L+ L H +
Sbjct: 11 RYKILEELGDGTCGSVYKAVNLETYEVVAVKKMKRKFYYWEECVNL-REVKALRKLNHPH 69
Query: 81 LICLEDIFLSPLEDIYFVTELQGTDLHRLLQTR--PLEKQFVQYFLYQILRGLKYVHSAG 138
+I L++I + +++F+ E +L+ +++ R P + ++ F+ Q+L+GL ++H G
Sbjct: 70 IIKLKEI-VREHNELFFIFECMDHNLYHIMKERERPFSEGEIRSFMSQMLQGLAHMHKNG 128
Query: 139 VIHRDLKPSNILINENCDLKICDFGLAR--IQDPQMTGYVSTRYYRAPEIMLTWQKYNVE 196
HRDLKP N+L+ N LKI DFGLAR P T YVSTR+YRAPE++L Y
Sbjct: 129 YFHRDLKPENLLVTNNI-LKIADFGLAREVASMPPYTEYVSTRWYRAPEVLLQSSLYTPA 187
Query: 197 VDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLKFVTSLP 256
VD+W+ G I AE+ PLFPG+ + Q I +LG P T ++ + S+
Sbjct: 188 VDMWAVGAILAELYALTPLFPGESEIDQLYKICCVLGKPD---WTTFPEAKSISRIMSIS 244
Query: 257 HRD--PVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPYLS-------PYHD 306
H + + N P+AIDL+ ++ +DP KR TA +AL HP+ S P HD
Sbjct: 245 HTEFPQTRIADLLPNAAPEAIDLINRLCSWDPLKRPTADEALNHPFFSMATQASYPIHD 303
>7297009 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 392
Score = 167 bits (423), Expect = 3e-41
Identities = 104/296 (35%), Positives = 155/296 (52%), Gaps = 16/296 (5%)
Query: 20 NRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHE 79
+RY L+ +G G++G+V D T VA+K+ ++ + K RE++LLK+L+H
Sbjct: 2 DRYEKLSRLGEGSYGVVYKCRDRETGALVAVKRFVESEDDPAIRKIALREIRLLKNLKHP 61
Query: 80 NLICLEDIFLSP--LEDIYFVTELQGTDLHRLLQ-TRPLEKQFVQYFLYQILRGLKYVHS 136
NL+ L ++F L ++ EL T LH L + + + + YQ L G+ Y H
Sbjct: 62 NLVSLLEVFRRKRRLHLVFEFCEL--TVLHELERHPQGCPEHLTKQICYQTLLGVAYCHK 119
Query: 137 AGVIHRDLKPSNILINENCDLKICDFGLARIQDP--QMTGYVSTRYYRAPEIMLTWQKYN 194
G +HRD+KP NIL+ +K+CDFG AR+ P T YV+TR+YRAPE+++ +Y
Sbjct: 120 QGCLHRDIKPENILLTAQGQVKLCDFGFARMLSPGENYTDYVATRWYRAPELLVGDTQYG 179
Query: 195 VEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLKFV-- 252
VD+W+ GC+FAE++ G+ L+PG+ V Q +I LG I K +
Sbjct: 180 TPVDVWAIGCLFAELVRGEALWPGRSDVDQLYLIRKTLGDLLPRHIQIFGQNEYFKGITL 239
Query: 253 ----TSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPYLSPY 304
T P D +P S+ QN P ID L+K L DP KR + H Y Y
Sbjct: 240 PVPPTLEPLEDKMPAKSQ-QN--PLTIDFLKKCLDKDPTKRWSCEKLTKHSYFDDY 292
>7300650 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 314
Score = 167 bits (422), Expect = 4e-41
Identities = 104/298 (34%), Positives = 155/298 (51%), Gaps = 30/298 (10%)
Query: 18 ITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLR 77
I + + +G G +G+V A T Q VA+KKI T + RE+ LLK+L+
Sbjct: 4 ILDNFQRAEKIGEGTYGIVYKARSNSTGQDVALKKIRLEGETEGVPSTAIREISLLKNLK 63
Query: 78 HENLICLEDIFLSPLEDIYFVTELQGTDLHRLLQTRP--LEKQFVQYFLYQILRGLKYVH 135
H N++ L D+ +S ++Y + E DL +L+ + Q ++ +++QIL + + H
Sbjct: 64 HPNVVQLFDVVISG-NNLYMIFEYLNMDLKKLMDKKKDVFTPQLIKSYMHQILDAVGFCH 122
Query: 136 SAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQMTGY---VSTRYYRAPEIMLTWQK 192
+ ++HRDLKP N+L++ +K+ DFGLAR + M Y V T +YRAPEI+L +
Sbjct: 123 TNRILHRDLKPQNLLVDTAGKIKLADFGLARAFNVPMRAYTHEVVTLWYRAPEILLGTKF 182
Query: 193 YNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLKFV 252
Y+ VDIWS GCIF+EMI + LFPG + Q I L +P E V
Sbjct: 183 YSTGVDIWSLGCIFSEMIMRRSLFPGDSEIDQLYRIFRTLSTP---------DETNWPGV 233
Query: 253 TSLPHRDPVPFSSRFQN----------LEPDAIDLLEKMLVFDPKKRITAADALAHPY 300
T LP F ++F E +A +L+ ML +DP RI+A DAL H Y
Sbjct: 234 TQLP-----DFKTKFPRWEGTNMPQPITEHEAHELIMSMLCYDPNLRISAKDALQHAY 286
>At3g05050 [D] KOG0600 Cdc2-related protein kinase
Length = 593
Score = 166 bits (421), Expect = 5e-41
Identities = 105/304 (34%), Positives = 166/304 (54%), Gaps = 22/304 (7%)
Query: 22 YTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHENL 81
+ ++ +G G + V A D+LT VA+KK+ + K RE+ +L+ L H N+
Sbjct: 138 FEKIDKIGSGTYSNVYKAKDSLTGNIVALKKVRCDVNERESLKFMAREILILRRLDHPNV 197
Query: 82 ICLEDIFLSPLED-IYFVTELQGTDLHRLLQTRPLE--KQFVQYFLYQILRGLKYVHSAG 138
I LE + S + +Y V DL L + ++ +Q V+ ++ Q+L GL++ H+ G
Sbjct: 198 IKLEGLVTSRMSSSLYLVFRYMDHDLAGLAASPEIKFTEQQVKCYMKQLLSGLEHCHNRG 257
Query: 139 VIHRDLKPSNILINENCDLKICDFGLARIQDP----QMTGYVSTRYYRAPEIMLTWQKYN 194
V+HRD+K SN+LI++ L+I DFGLA D +MT V T +YR+PE++ +Y+
Sbjct: 258 VLHRDIKGSNLLIDDGGVLRIGDFGLATFFDASKRQEMTNRVVTLWYRSPELLHGVVEYS 317
Query: 195 VEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLKFVTS 254
V VD+WSAGCI AE++ G+ + PG++ V Q I L GSP ++ I +T K
Sbjct: 318 VGVDLWSAGCILAELLAGRAIMPGRNEVEQLHRIYKLCGSPSEEYWKKIRLPSTHKHA-- 375
Query: 255 LPHRDPVPFSSR-----FQNLEPDAIDLLEKMLVFDPKKRITAADALAHPYLSPYHDPTD 309
H P+P R +++ P+A+ LL+ +L DP +R TA D L + T
Sbjct: 376 --HHKPLPQYKRRIREVYKDFSPEALSLLDTLLALDPAERQTATDVLMSDFF------TT 427
Query: 310 EPIA 313
EP+A
Sbjct: 428 EPLA 431
>7292375 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 509
Score = 166 bits (420), Expect = 6e-41
Identities = 107/299 (35%), Positives = 157/299 (51%), Gaps = 31/299 (10%)
Query: 22 YTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIM------KPFSTSVLAKRTYRELKLLKH 75
Y L P+G G++ V LT Q VA+K+I PF+ RE LLK
Sbjct: 192 YVKLEPLGEGSYATVYKGFSKLTYQRVALKEIRLQEEEGAPFTA-------IREASLLKE 244
Query: 76 LRHENLICLEDIFLSPLEDIYFVTELQGTDLHRLLQTRP--LEKQFVQYFLYQILRGLKY 133
L+H N++ L DI + E + FV E TDL + ++ P L+ + V+ FL+Q+LRGL Y
Sbjct: 245 LKHSNIVTLHDI-VHTRETLTFVFEYVNTDLSQYMEKHPGGLDHRNVRLFLFQLLRGLSY 303
Query: 134 VHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQMTGY---VSTRYYRAPEIMLTW 190
H V+HRD+KP N+LI++ +LK+ DFGLAR + Y V T +YR P+++L
Sbjct: 304 CHKRRVLHRDVKPQNLLISDCGELKLADFGLARAKSVPSHTYSHEVVTLWYRPPDVLLGS 363
Query: 191 QKYNVEVDIWSAGCIFAEMIEGKPLFPG-KDHVHQFSIITDLLGSPPKDVIDTICSENTL 249
+Y+ +D+W GCIF EM+ G P FPG +D Q I LLG+P +D +
Sbjct: 364 TEYSTSLDMWGVGCIFVEMVTGMPTFPGIRDTYDQLDKIFKLLGTPTEDTWPGV-----T 418
Query: 250 KFVTSLPHRDPVPFSSRFQNLEPDAIDLLE------KMLVFDPKKRITAADALAHPYLS 302
F PH+ + + P D++E L +P++R+ A DAL HPY +
Sbjct: 419 HFPGYKPHKLGFYRPRKLGHNFPRLYDIIEGETIANGFLQLNPEQRLGADDALQHPYFA 477
>At5g45430 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 530
Score = 166 bits (419), Expect = 8e-41
Identities = 104/301 (34%), Positives = 169/301 (55%), Gaps = 19/301 (6%)
Query: 21 RYTNLNPVGMGAFGLVCSATDTLTSQ--------PVAIKKIMKPFSTSVLAKRTYRELKL 72
RYT L VG G FG V A + T++ VAIK++ K + + RE+K
Sbjct: 3 RYTLLKEVGDGTFGNVWRAVNKQTNEVGTEVFYVQVAIKRMKKKYFSWEECVNL-REVKS 61
Query: 73 LKHLRHENLICLEDIFLSPLEDIYFVTELQGTDLHRLLQTRP--LEKQFVQYFLYQILRG 130
L + H N++ L+++ + + +YFV E +L++L++ RP + ++ + +Q+ +G
Sbjct: 62 LSRMNHPNIVKLKEV-IRENDILYFVFEYMECNLYQLMKDRPKHFAESDIRNWCFQVFQG 120
Query: 131 LKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQD--PQMTGYVSTRYYRAPEIML 188
L Y+H G HRDLKP N+L++++ +KI D GLAR D P T YVSTR+YRAPE++L
Sbjct: 121 LSYMHQRGYFHRDLKPENLLVSKDV-IKIADLGLAREIDSSPPYTEYVSTRWYRAPEVLL 179
Query: 189 TWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDV-IDTICSEN 247
Y +VD+W+ G I AE++ +PLFPG + I ++GSP ++ ++ + +
Sbjct: 180 QSYVYTSKVDMWAMGAIMAELLSLRPLFPGASEADEIYKICSVIGSPTEETWLEGLNLAS 239
Query: 248 TLKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPYL-SPYHD 306
+ + P V SS DA++L+E++ +DP R T A+AL HP+ S Y+
Sbjct: 240 VINY--QFPQFPGVHLSSVMPYASADAVNLIERLCSWDPCNRPTTAEALQHPFFQSCYYI 297
Query: 307 P 307
P
Sbjct: 298 P 298
>Hs4502743 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 346
Score = 165 bits (418), Expect = 1e-40
Identities = 105/296 (35%), Positives = 156/296 (52%), Gaps = 12/296 (4%)
Query: 21 RYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSV---LAKRTYRELKLLKHLR 77
RY L+ +G G F V A D T+Q VAIKKI + + + RE+KLL+ L
Sbjct: 11 RYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELS 70
Query: 78 HENLICLEDIFLSPLEDIYFVTELQGTDLHRLLQTRPL--EKQFVQYFLYQILRGLKYVH 135
H N+I L D F +I V + TDL +++ L ++ ++ L+GL+Y+H
Sbjct: 71 HPNIIGLLDAF-GHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLH 129
Query: 136 SAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQMTGY---VSTRYYRAPEIMLTWQK 192
++HRDLKP+N+L++EN LK+ DFGLA+ Y V TR+YRAPE++ +
Sbjct: 130 QHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARM 189
Query: 193 YNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLKFV 252
Y V VD+W+ GCI AE++ P PG + Q + I + LG+P ++ +CS
Sbjct: 190 YGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTF 249
Query: 253 TSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPYLSPYHDPT 308
S P +P F D +DL++ + +F+P RITA AL Y S PT
Sbjct: 250 KSFP---GIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPT 302
>At5g63370 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 612
Score = 165 bits (418), Expect = 1e-40
Identities = 108/296 (36%), Positives = 157/296 (52%), Gaps = 17/296 (5%)
Query: 20 NRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKI-MKP--FSTSV-LAKRTYRELKLLKH 75
N + LN + G +G+V A D T + VA+KKI MK F + RE+ +L
Sbjct: 295 NEFQKLNKINEGTYGIVYKARDEKTKEIVALKKIKMKEDRFEEEYGFPLTSLREINILLS 354
Query: 76 LRHENLICLEDIFLSPLED--IYFVTELQGTDLHRLLQTR--PLEKQFVQYFLYQILRGL 131
H ++ ++++ + D +Y V E DL ++ R P V+ + Q+L GL
Sbjct: 355 CNHPAIVNVKEVVVGGKNDNDVYMVMEHLEHDLRGVMDRRKEPFSTSEVKCLMMQLLDGL 414
Query: 132 KYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQMTGY---VSTRYYRAPEIML 188
KY+H+ +IHRDLKPSN+L+N +LKICDFG+AR + Y V T++YR PE++L
Sbjct: 415 KYLHTNWIIHRDLKPSNLLMNNCGELKICDFGMARQYGSPIKPYTQMVITQWYRPPELLL 474
Query: 189 TWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICS--E 246
++Y+ VD+WS GCI AE++ KPLFPGK + Q I +LG+P + + S
Sbjct: 475 GAKEYSTAVDMWSVGCIMAELLSQKPLFPGKSELDQLQKIFAVLGTPNEAIWPGFSSFPN 534
Query: 247 NTLKFVTS----LPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAH 298
KF T L + P Q L DLL +L DP+KR+T DAL H
Sbjct: 535 AKAKFPTQPYNMLRKKFPAISFVGGQILSERGFDLLNSLLTLDPEKRLTVEDALNH 590
>At3g61160 [G] KOG0658 Glycogen synthase kinase-3
Length = 431
Score = 165 bits (418), Expect = 1e-40
Identities = 104/304 (34%), Positives = 163/304 (53%), Gaps = 25/304 (8%)
Query: 19 TNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRH 78
T Y + +G G+FG+V A T + VAIKK+++ + REL++++ L H
Sbjct: 99 TISYRAEHVIGTGSFGVVFQAKCLETEEKVAIKKVLQD------KRYKNRELQIMRMLDH 152
Query: 79 ENLICLEDIFLSPLE--DIYF--VTELQGTDLHRLLQTRPLEKQ-----FVQYFLYQILR 129
N++ L+ F S E ++Y V E ++R ++ Q ++Q + YQI R
Sbjct: 153 PNVVELKHSFFSTTEKDELYLNLVLEYVPETIYRASRSYTKMNQHMPLIYIQLYTYQICR 212
Query: 130 GLKYVHSA-GVIHRDLKPSNILINE-NCDLKICDFGLARIQDP--QMTGYVSTRYYRAPE 185
+ Y+H GV HRD+KP N+L+N ++KICDFG A++ P Y+ +RYYRAPE
Sbjct: 213 AMNYLHQVVGVCHRDIKPQNLLVNNVTHEVKICDFGSAKMLIPGEPNISYICSRYYRAPE 272
Query: 186 IMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICS 245
++ +Y +D+WS GC+ AE+ G PLFPG+ V Q I +LG+P ++ I +
Sbjct: 273 LIFGATEYTSAIDMWSVGCVMAELFLGHPLFPGETSVDQLVEIIKILGTPAREEIKNMNP 332
Query: 246 E-NTLKFVTSLPHRDPVPFSSRF-QNLEPDAIDLLEKMLVFDPKKRITAADALAHPYLSP 303
N KF P P+ F + + P+A+DL ++L + P R TA +A AHP+
Sbjct: 333 RYNDFKF----PQIKAQPWHKIFRRQVSPEAMDLASRLLQYSPNLRCTALEACAHPFFDD 388
Query: 304 YHDP 307
DP
Sbjct: 389 LRDP 392
>At5g63610 [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 470
Score = 165 bits (417), Expect = 1e-40
Identities = 117/346 (33%), Positives = 177/346 (50%), Gaps = 34/346 (9%)
Query: 17 EITNRYTNLNPVGMGAFGLVCSA-TDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKH 75
E +Y + +G G +GLV A T T +P+AIKK + ++ RE+ LL+
Sbjct: 20 EWLQQYNLVGKIGEGTYGLVFLARTKTPPKRPIAIKKFKQSKDGDGVSPTAIREIMLLRE 79
Query: 76 LRHENLICLEDIFLSPLE-DIYFVTELQGTDLHRLLQTR------PLEKQFVQYFLYQIL 128
+ HEN++ L ++ ++ + +Y + DL+ +++ L V+ L+Q+L
Sbjct: 80 ISHENVVKLVNVHINFADMSLYLAFDYAEYDLYEIIRHHRDKVGHSLNTYTVKSLLWQLL 139
Query: 129 RGLKYVHSAGVIHRDLKPSNILI----NENCDLKICDFGLARIQDPQM-----TGYVSTR 179
GL Y+HS +IHRDLKPSNIL+ E+ +KI DFGLARI + G V T
Sbjct: 140 NGLNYLHSNWIIHRDLKPSNILVMGDAEEHGIVKIADFGLARIYQAPLKPLSDNGVVVTI 199
Query: 180 YYRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKD--------HVHQFSIITDL 231
+YRAPE++L + Y VD+W+ GCIFAE++ KPLF G + + Q I +
Sbjct: 200 WYRAPELLLGSKHYTSAVDMWAVGCIFAELLTLKPLFQGAEAKSSQNPFQLDQLDKIFKI 259
Query: 232 LGSPPKDVIDTICS----ENTLKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPK 287
LG P D T+ + +N ++ + + + + N + A DLL KML +DP
Sbjct: 260 LGHPTMDKWPTLVNLPHWQNDVQHIQAHKYDSVGLHNVVHLNQKSPAYDLLSKMLEYDPL 319
Query: 288 KRITAADALAHPYLSPYHDP---TDEPIAEAKFDWNFNDADLPVDT 330
KRITA+ AL H Y DP + +A + N N PVDT
Sbjct: 320 KRITASQALEHEYFR--MDPLPGRNAFVASQPMEKNVNYPTRPVDT 363
>At4g00720 [G] KOG0658 Glycogen synthase kinase-3
Length = 472
Score = 165 bits (417), Expect = 1e-40
Identities = 103/303 (33%), Positives = 161/303 (52%), Gaps = 23/303 (7%)
Query: 19 TNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRH 78
T Y VG G+FG+V A T + VAIKK+++ + REL++++ H
Sbjct: 135 TISYMAQRVVGTGSFGVVFQAKCLETGEQVAIKKVLQD------KRYKNRELQIMRLQDH 188
Query: 79 ENLICLEDIFLSPLE--DIYFVTELQ-------GTDLHRLLQTRPLEKQFVQYFLYQILR 129
N++ L F S + ++Y L+ H + + FVQ + YQI R
Sbjct: 189 PNVVRLRHSFFSTTDKDELYLNLVLEYVPETVYRASKHYTKMNQHMPIIFVQLYTYQICR 248
Query: 130 GLKYVHSA-GVIHRDLKPSNILIN-ENCDLKICDFGLARIQDP--QMTGYVSTRYYRAPE 185
L Y+H GV HRD+KP N+L+N + LKICDFG A++ P Y+ +RYYRAPE
Sbjct: 249 ALNYLHRVVGVCHRDIKPQNLLVNPQTHQLKICDFGSAKMLVPGEPNISYICSRYYRAPE 308
Query: 186 IMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICS 245
++ +Y +D+WS GC+ AE++ G+PLFPG+ + Q I +LG+P ++ I + +
Sbjct: 309 LIFGATEYTNAIDMWSGGCVMAELLLGQPLFPGESGIDQLVEIIKILGTPTREEIRCM-N 367
Query: 246 ENTLKFVTSLPHRDPVPFSSRF-QNLEPDAIDLLEKMLVFDPKKRITAADALAHPYLSPY 304
N +F P P+ F + + P+A+DL+ ++L + P R TA +A AHP+
Sbjct: 368 PNYTEF--KFPQIKAHPWHKIFHKRMPPEAVDLVSRLLQYSPNLRCTALEACAHPFFDDL 425
Query: 305 HDP 307
DP
Sbjct: 426 RDP 428
>At1g54610 [D] KOG0600 Cdc2-related protein kinase
Length = 572
Score = 165 bits (417), Expect = 1e-40
Identities = 109/315 (34%), Positives = 171/315 (53%), Gaps = 24/315 (7%)
Query: 13 GTVFEITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKI----MKPFSTSVLAKRTYR 68
G V + + ++ +G G + V A D LT + VA+KK+ ++P S +A R
Sbjct: 109 GWVPRKADTFEKIDKIGQGTYSNVYKAKDMLTGKIVALKKVRFDNLEPESVKFMA----R 164
Query: 69 ELKLLKHLRHENLICLEDIFLSPLE-DIYFVTELQGTDLHRLLQTRPLE--KQFVQYFLY 125
E+ +L+ L H N++ LE + S + +Y V + DL L + ++ + V+ +
Sbjct: 165 EILVLRRLDHPNVVKLEGLVTSRMSCSLYLVFQYMDHDLAGLASSPVVKFSESEVKCLMR 224
Query: 126 QILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQ----MTGYVSTRYY 181
Q++ GL++ HS GV+HRD+K SN+LI++ LKI DFGLA I DP MT V T +Y
Sbjct: 225 QLISGLEHCHSRGVLHRDIKGSNLLIDDGGVLKIADFGLATIFDPNHKRPMTSRVVTLWY 284
Query: 182 RAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVID 241
RAPE++L Y V +D+WSAGCI AE++ G+P+ PG+ V Q I L GSP +D
Sbjct: 285 RAPELLLGATDYGVGIDLWSAGCILAELLAGRPIMPGRTEVEQLHKIYKLCGSPSED--- 341
Query: 242 TICSENTLKFVTSLPHRDPVPFSSR--FQNLEPDAIDLLEKMLVFDPKKRITAADALAHP 299
+ R+P S R F++ P ++ L++ +L +P+ R TA+ AL
Sbjct: 342 -YWKKGKFTHGAIYKPREPYKRSIRETFKDFPPSSLPLIDALLSIEPEDRQTASAALKSE 400
Query: 300 YLS--PYH-DPTDEP 311
+ + PY +P D P
Sbjct: 401 FFTSEPYACEPADLP 415
>Hs16160923 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 472
Score = 164 bits (416), Expect = 2e-40
Identities = 97/284 (34%), Positives = 150/284 (52%), Gaps = 8/284 (2%)
Query: 22 YTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHENL 81
Y L+ +G G + V LT VA+K+I RE+ LLK+L+H N+
Sbjct: 142 YVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHEEGAPCT-AIREVSLLKNLKHANI 200
Query: 82 ICLEDIFLSPLEDIYFVTELQGTDLHRLLQT--RPLEKQFVQYFLYQILRGLKYVHSAGV 139
+ L D+ + + V E +DL + L + V+ F++Q+LRGL Y H +
Sbjct: 201 VTLHDLIHTD-RSLTLVFEYLDSDLKQYLDHCGNLMSMHNVKIFMFQLLRGLAYCHHRKI 259
Query: 140 IHRDLKPSNILINENCDLKICDFGLARIQDPQMTGY---VSTRYYRAPEIMLTWQKYNVE 196
+HRDLKP N+LINE +LK+ DFGLAR + Y V T +YR P+++L +Y+
Sbjct: 260 LHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYSTP 319
Query: 197 VDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLKFVTSLP 256
+D+W GCI EM G+PLFPG + +I LLG+P ++ + + + + S P
Sbjct: 320 IDMWGVGCIHYEMATGRPLFPGSTVKEELHLIFRLLGTPTEETWPGVTAFSEFR-TYSFP 378
Query: 257 HRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPY 300
P P + L+ D I LL +L+++ K R++A AL+H Y
Sbjct: 379 CYLPQPLINHAPRLDTDGIHLLSSLLLYESKSRMSAEAALSHSY 422
>7303804 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 387
Score = 164 bits (416), Expect = 2e-40
Identities = 96/289 (33%), Positives = 158/289 (54%), Gaps = 11/289 (3%)
Query: 20 NRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHE 79
+ + LN VG G++G+V A DT +++ VA+KK+ L RE+ +LK HE
Sbjct: 51 SEFEKLNRVGEGSYGIVYRARDTRSNEIVALKKVRMDQEKDGLPISGLREIMILKQCHHE 110
Query: 80 NLICLEDIFLSP-LEDIYFVTELQGTDLHRLLQ--TRPLEKQFVQYFLYQILRGLKYVHS 136
N++ L ++ + L+ I+ V + DL +L ++P + V+ Q+L+ LKY+HS
Sbjct: 111 NIVRLREVVVGKSLDSIFLVMDFCEQDLASVLDNMSQPFTESEVKCITLQVLKALKYLHS 170
Query: 137 AGVIHRDLKPSNILINENCDLKICDFGLARI---QDPQMTGYVSTRYYRAPEIMLTWQKY 193
+IHRDLK SN+L+ + +K+ DFGLAR+ MT + T +YRAPE++L + +
Sbjct: 171 RFMIHRDLKVSNLLMTDKGCIKVADFGLARMFSNPPKPMTPQMVTLWYRAPELLLGCRTH 230
Query: 194 NVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLKFVT 253
VD+W+ GCI E++ GKPL PG + Q +I DLLG+P + + ++ T
Sbjct: 231 TTAVDMWAFGCILGELLLGKPLLPGNSEIAQLDMIIDLLGAPSESIWPGFADLPAVQNFT 290
Query: 254 --SLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPY 300
P+ + P +F + +LL + +++PK R TA + L Y
Sbjct: 291 LSQQPYNNLTP---KFHMIGQSGRNLLNILFIYNPKTRATAEECLKSKY 336
>At3g54180 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 309
Score = 164 bits (415), Expect = 2e-40
Identities = 104/301 (34%), Positives = 156/301 (51%), Gaps = 24/301 (7%)
Query: 21 RYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHE- 79
+Y L VG G +G V A + T + VA+KK + RE+ LL+ L
Sbjct: 3 KYEKLEKVGEGTYGKVYKAMEKGTGKLVALKKTRLEMDEEGIPPTALREISLLQMLSTSI 62
Query: 80 ---NLICLEDIFL------SPLEDIYFVTELQGTDLHRLLQT-------RPLEKQFVQYF 123
L+C+E + S ++Y V E TDL + + + +PLE +Q
Sbjct: 63 YVVRLLCVEHVHQPSTKSQSTKSNLYLVFEYLDTDLKKFIDSYRKGPNPKPLEPFLIQKL 122
Query: 124 LYQILRGLKYVHSAGVIHRDLKPSNILINENCDL-KICDFGLARIQDPQMTGY---VSTR 179
++Q+ +G+ + HS GV+HRDLKP N+L+ ++ +L KI D GL R + Y + T
Sbjct: 123 MFQLCKGVAHCHSHGVLHRDLKPQNLLLVKDKELLKIADLGLGRAFTVPLKSYTHEIVTL 182
Query: 180 YYRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDV 239
+YRAPE++L Y+ VD+WS GCIFAEM+ + LFPG Q I LLG+P +
Sbjct: 183 WYRAPEVLLGSTHYSTGVDMWSVGCIFAEMVRRQALFPGDSEFQQLLHIFRLLGTPTEQQ 242
Query: 240 IDTICSENTLKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHP 299
+ +TL+ P +P + +L P +DLL KML ++P +RI+A AL HP
Sbjct: 243 WPGV---STLRDWHVYPKWEPQDLTLAVPSLSPQGVDLLTKMLKYNPAERISAKTALDHP 299
Query: 300 Y 300
Y
Sbjct: 300 Y 300
>7290565 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 353
Score = 164 bits (414), Expect = 3e-40
Identities = 100/301 (33%), Positives = 163/301 (53%), Gaps = 12/301 (3%)
Query: 19 TNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSV---LAKRTYRELKLLKH 75
T RY L+ +G G F V A DT+T+Q VA+KKI K + + RE+K+L+
Sbjct: 9 TERYAKLSFLGEGQFATVYKARDTVTNQIVAVKKIKKGSREDARDGINRTALREIKILQE 68
Query: 76 LRHENLICLEDIFLSPLEDIYFVTELQGTDLHRLLQTRP--LEKQFVQYFLYQILRGLKY 133
L+HEN+I L D+F L ++ V + TDL +++ L + ++ + L+GL+Y
Sbjct: 69 LQHENIIGLVDVF-GQLSNVSLVFDFMDTDLEVIIKDNKIILTQANIKAYAIMTLKGLEY 127
Query: 134 VHSAGVIHRDLKPSNILINENCDLKICDFGLAR-IQDPQM--TGYVSTRYYRAPEIMLTW 190
+H ++HRDLKP+N+L+N + LKI DFGLA+ P T +V TR+YR+PE++
Sbjct: 128 LHLNWILHRDLKPNNLLVNSDGILKIGDFGLAKSFGSPNRIYTHHVVTRWYRSPELLFGA 187
Query: 191 QKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLK 250
++Y VD+W+ GCI AE++ P PG + Q + I LG+P + + +
Sbjct: 188 RQYGTGVDMWAVGCILAELMLRVPFMPGDSDLDQLTRIFSTLGTPTEAEWPHLSKLHDYL 247
Query: 251 FVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPYLSPYHDPTDE 310
+ P P + F D I L++++ +P +R++ +AL+ PY + PT
Sbjct: 248 QFRNFP---GTPLDNIFTAAGNDLIHLMQRLFAMNPLRRVSCREALSMPYFANKPAPTVG 304
Query: 311 P 311
P
Sbjct: 305 P 305
>CE20258 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 353
Score = 163 bits (413), Expect = 4e-40
Identities = 96/291 (32%), Positives = 162/291 (54%), Gaps = 13/291 (4%)
Query: 20 NRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHE 79
++Y L+ +G G++G+V + T Q VAIKK ++ + K RE+++LK L+H+
Sbjct: 2 DKYDRLSKLGEGSYGVVYKCKNRDTGQIVAIKKFVETEDDPHIKKIALREIRMLKQLKHQ 61
Query: 80 NLICLEDIFLSPLEDIYFVTELQGTDLHRLLQTRP--LEKQFVQYFLYQILRGLKYVHSA 137
NL+ L ++F + ++ V EL + L+ P + + ++ +YQ+L LK+ HS
Sbjct: 62 NLVGLIEVFKRNRK-LHLVFELCDRTVLHELEKNPHGVNDELIKKIIYQLLEALKFCHSH 120
Query: 138 GVIHRDLKPSNILINENCDLKICDFGLARIQDP--QMTGYVSTRYYRAPEIMLTWQKYNV 195
IHRD+KP NI + N +K+ DFG ARI + T YV+TR+YR+PE+++ +Y
Sbjct: 121 KCIHRDVKPENIFLTRNDQVKLGDFGFARIINTTEMYTDYVATRWYRSPELLVGDVQYGP 180
Query: 196 EVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGS-PPKDVIDTICSENTLKFVTS 254
VDIW+ GC++AE++ G+ L+PG+ + Q I LG P+ + +I N F S
Sbjct: 181 PVDIWAVGCVYAELLTGEALWPGRSDIDQLYHIRKTLGEFLPRHI--SIFRTNQFFFGLS 238
Query: 255 LP---HRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPYLS 302
+P H +P+P S+ N +D L+K P +R + ++ + H S
Sbjct: 239 IPEPEHLEPLP--SKLPNASSAQLDFLQKCFEMSPDRRFSCSELMLHGIFS 287
>At1g33770 [D] KOG0600 Cdc2-related protein kinase
Length = 614
Score = 163 bits (413), Expect = 4e-40
Identities = 107/308 (34%), Positives = 166/308 (53%), Gaps = 27/308 (8%)
Query: 11 IFGTVFEITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKI----MKPFSTSVLAKRT 66
I G V + + L+ +G G + +V A D T + VA+KK+ M P S +A
Sbjct: 130 IKGWVPRRADSFEKLDKIGQGTYSIVYKARDLETGKIVAMKKVRFANMDPESVRFMA--- 186
Query: 67 YRELKLLKHLRHENLICLEDIFLSPLE-DIYFVTELQGTDLHRLLQTRP---LEKQFVQY 122
RE+ +L+ L H N++ L+ + S L ++ V E DL L RP + ++
Sbjct: 187 -REINILRKLDHPNVMKLQCLVTSKLSGSLHLVFEYMEHDLSGLA-LRPGVKFTEPQIKC 244
Query: 123 FLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARI----QDPQMTGYVST 178
F+ Q+L GL++ HS G++HRD+K SN+L+N + LKI DFGLA QD +T V T
Sbjct: 245 FMKQLLCGLEHCHSRGILHRDIKGSNLLVNNDGVLKIGDFGLASFYKPDQDQPLTSRVVT 304
Query: 179 RYYRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKD 238
+YRAPE++L +Y +D+WS GCI AE+ KP+ PG+ V Q I L GSP ++
Sbjct: 305 LWYRAPELLLGSTEYGPAIDLWSVGCILAELFVCKPIMPGRTEVEQMHKIFKLCGSPSEE 364
Query: 239 VIDTICSENTLKFVTSLPHRDPVPFS----SRFQNLEPDAIDLLEKMLVFDPKKRITAAD 294
NT KF + ++ P+ F+NL ++DLL+K+L +P+KR +A+
Sbjct: 365 F------WNTTKFPQATSYKPQHPYKRVLLETFKNLSSSSLDLLDKLLSVEPEKRCSASS 418
Query: 295 ALAHPYLS 302
L + +
Sbjct: 419 TLLSEFFT 426
>At5g14640 [G] KOG0658 Glycogen synthase kinase-3
Length = 408
Score = 163 bits (412), Expect = 5e-40
Identities = 103/295 (34%), Positives = 165/295 (55%), Gaps = 27/295 (9%)
Query: 28 VGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHENLICLEDI 87
VG G+FG+V A T + VAIKK+++ + REL+ ++ L H N++ L+
Sbjct: 80 VGQGSFGIVFQAKCLETGETVAIKKVLQD------KRYKNRELQTMRLLDHPNVVSLKHC 133
Query: 88 FLSPLE--DIYF--VTELQGTDLHRLLQTRPLEKQ-----FVQYFLYQILRGLKYVHSA- 137
F S E ++Y V E ++R+ + Q +V+ + YQI R L Y+H
Sbjct: 134 FFSTTEKDELYLNLVLEYVPETVYRVSKHYSRANQRMPIIYVKLYTYQICRALAYIHGGV 193
Query: 138 GVIHRDLKPSNILINENC-DLKICDFGLARIQ---DPQMTGYVSTRYYRAPEIMLTWQKY 193
GV HRD+KP N+L+N + +K+CDFG A++ +P ++ Y+ +RYYRAPE++ +Y
Sbjct: 194 GVCHRDIKPQNLLVNPHTHQVKLCDFGSAKVLVKGEPNIS-YICSRYYRAPELIFGATEY 252
Query: 194 NVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLKFVT 253
+DIWSAGC+ AE++ G+PLFPG+ V Q I +LG+P ++ I + + N +F
Sbjct: 253 TTTIDIWSAGCVLAELLLGQPLFPGESGVDQLVEIIKVLGTPTREEIKCM-NPNYTEF-- 309
Query: 254 SLPHRDPVPFSSRF-QNLEPDAIDLLEKMLVFDPKKRITAADALAHPYLSPYHDP 307
P P+ F + P+A+DL+ ++L + P R TA A+ HP+ DP
Sbjct: 310 KFPQIKAHPWHKIFHKRTPPEAVDLVSRLLQYSPNLRSTA--AIVHPFFDELRDP 362
>At1g67580 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 752
Score = 163 bits (412), Expect = 5e-40
Identities = 99/293 (33%), Positives = 157/293 (52%), Gaps = 12/293 (4%)
Query: 20 NRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHE 79
+ + LN + G +G+V A D T + VA+KK+ + RE+ +L H
Sbjct: 404 DEFERLNKIDEGTYGVVYRAKDKKTGEIVALKKVKMEKEREGFPLTSLREINILLSFHHP 463
Query: 80 NLICLEDIFL-SPLEDIYFVTELQGTDLHRLLQT--RPLEKQFVQYFLYQILRGLKYVHS 136
+++ ++++ + S L+ I+ V E DL L++T + + V+ + Q+L G+KY+H
Sbjct: 464 SIVDVKEVVVGSSLDSIFMVMEYMEHDLKALMETMKQRFSQSEVKCLMLQLLEGVKYLHD 523
Query: 137 AGVIHRDLKPSNILINENCDLKICDFGLARIQDPQMTGY---VSTRYYRAPEIMLTWQKY 193
V+HRDLK SN+L+N +LKICDFGLAR + Y V T +YRAPE++L ++Y
Sbjct: 524 NWVLHRDLKTSNLLLNNRGELKICDFGLARQYGSPLKPYTHLVVTLWYRAPELLLGAKQY 583
Query: 194 NVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLK--F 251
+ +D+WS GCI AE++ PLF GK Q I +LG+P + + +K F
Sbjct: 584 STAIDMWSLGCIMAELLMKAPLFNGKTEFDQLDKIFRILGTPNESIWPGFSKLPGVKVNF 643
Query: 252 V----TSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPY 300
V L + P + L DLL K+L +DP++RIT +AL H +
Sbjct: 644 VKHQYNLLRKKFPATSFTGAPVLSDAGFDLLNKLLTYDPERRITVNEALKHDW 696
>SPBC8D2.01 [G] KOG0658 Glycogen synthase kinase-3
Length = 381
Score = 162 bits (411), Expect = 7e-40
Identities = 114/354 (32%), Positives = 182/354 (51%), Gaps = 35/354 (9%)
Query: 1 MSNEEFIRTQIF--GTVFEI-TNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPF 57
MS++ + T++ GT E T Y +G G+FG+V A T +A+K++++
Sbjct: 1 MSDDSHLETKVVTDGTTGEKKTISYEPCRVLGSGSFGVVIQAKLVGTPGFIAVKRVLQD- 59
Query: 58 STSVLAKRTYRELKLLKHLRHENLICLEDIFLS--PLED-------IYFVTELQGTDLHR 108
+ REL++++ + H N+I L F + P +D + ++ E D+
Sbjct: 60 -----KRYKNRELQIMRAISHPNIIKLIAFFHTHNPSKDETHLCLLLEYMPETVFDDMRW 114
Query: 109 LLQTRP-LEKQFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCD-LKICDFGLAR 166
+ R + ++ + +Q+ R L Y+HS GV HRD+KP N+L++ LK+CDFG A+
Sbjct: 115 YTRRRKSIPNLSIKLYAFQLFRALAYLHSTGVCHRDIKPQNLLVDYKTGILKLCDFGSAK 174
Query: 167 IQDPQM--TGYVSTRYYRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQ 224
+ P Y+ +RYYRAPE++ Y ++D+WSA C+ AE+ G+PLFPG V Q
Sbjct: 175 VLVPSEPNVSYICSRYYRAPELVFGATHYTTKIDVWSAACVIAELFIGRPLFPGDSSVEQ 234
Query: 225 FSIITDLLGSPPKDVIDTICSENTLKFVTSLPHRDPVPFSSRF-QNLEPDAIDLLEKMLV 283
I +LG+P I ++ + N + SLP+ P S N +A+DLL KML
Sbjct: 235 LVEIIRVLGTPSYHEI-SVMNPNYVNH--SLPNVRPHTLESVMPHNCTKNAMDLLHKMLT 291
Query: 284 FDPKKRITAADALAHPYLSPYHDPT-------DEPIAEAKFD--WNFNDADLPV 328
+ P KRI+A + L HP+ DP DE E +NFN A+L +
Sbjct: 292 YVPSKRISAIEVLTHPFFDELRDPNCMYHCSRDEGTIERHLPPLFNFNLAELSI 345
>At1g71530 [D] KOG0600 Cdc2-related protein kinase
Length = 655
Score = 162 bits (411), Expect = 7e-40
Identities = 107/303 (35%), Positives = 159/303 (52%), Gaps = 17/303 (5%)
Query: 11 IFGTVFEITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKI----MKPFSTSVLAKRT 66
I G V + L+ +G G + V A D T + VA+KK+ M P S +A
Sbjct: 136 IKGWVPRCAESFEKLDKIGQGTYSSVYKARDLETGKIVAMKKVRFVNMDPESVRFMA--- 192
Query: 67 YRELKLLKHLRHENLICLEDIFLSPLE-DIYFVTELQGTDLHRLLQTRPLE--KQFVQYF 123
RE+ +L+ L H N++ LE + S L +Y V E DL L T ++ + ++ +
Sbjct: 193 -REILILRKLDHPNVMKLEGLVTSRLSGSLYLVFEYMEHDLAGLAATPGIKFSEPQIKCY 251
Query: 124 LYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQ----DPQMTGYVSTR 179
+ Q+ RGL++ H G++HRD+K SN+LIN LKI DFGLA D Q+T V T
Sbjct: 252 MQQLFRGLEHCHRRGILHRDIKGSNLLINNEGVLKIGDFGLANFYRGDGDLQLTSRVVTL 311
Query: 180 YYRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDV 239
+YRAPE++L +Y +D+WSAGCI E+ GKP+ PG+ V Q I L GSP +D
Sbjct: 312 WYRAPELLLGATEYGPAIDLWSAGCILTELFAGKPIMPGRTEVEQMHKIFKLCGSPSEDY 371
Query: 240 IDTICSENTLKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHP 299
F S P++ PV + F + A+ L+ K+L +P+KR +AA L
Sbjct: 372 WRRATLPLATSFKPSHPYK-PV-LAETFNHFPSSALMLINKLLAIEPEKRGSAASTLRSE 429
Query: 300 YLS 302
+ +
Sbjct: 430 FFT 432
>At5g44290 [D] KOG0600 Cdc2-related protein kinase
Length = 644
Score = 162 bits (410), Expect = 9e-40
Identities = 108/304 (35%), Positives = 157/304 (51%), Gaps = 20/304 (6%)
Query: 22 YTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHENL 81
+ L +G G + V A D ++ VA+K++ S K RE+ +++ L H N+
Sbjct: 137 FEKLEKIGQGTYSSVYKARDLTNNKIVALKRVRFDLSDLESVKFMAREIIVMRRLDHPNV 196
Query: 82 ICLEDIFLSPLED-IYFVTELQGTDLHRLLQTRPLE--KQFVQYFLYQILRGLKYVHSAG 138
+ LE + + + +Y V E DL L ++ + V+ ++ Q+L GL + HS G
Sbjct: 197 LKLEGLITASVSSSLYLVFEYMDHDLVGLASIPGIKFSEPQVKCYMQQLLSGLHHCHSRG 256
Query: 139 VIHRDLKPSNILINENCDLKICDFGLARIQDPQ----MTGYVSTRYYRAPEIMLTWQKYN 194
V+HRD+K SN+LI+ N LKI DFGLA DPQ +T V T +YR PE++L Y
Sbjct: 257 VLHRDIKGSNLLIDSNGVLKIADFGLATFFDPQNCVPLTSRVVTLWYRPPELLLGACHYG 316
Query: 195 VEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLKFVTS 254
V VD+WS GCI E+ GKP+ GK V Q I L GSP +D LK S
Sbjct: 317 VGVDLWSTGCILGELYSGKPILAGKTEVEQLHKIFKLCGSPTEDY------WRKLKLPPS 370
Query: 255 LPHRDPVPFSSR----FQNLEPDAIDLLEKMLVFDPKKRITAADALAHPYL--SPYH-DP 307
R +P+ R F++L + + LLE +L DP +R +AA AL Y P+ DP
Sbjct: 371 AAFRPALPYGRRVAEMFKDLPTNVLSLLEALLSIDPDRRGSAARALESEYFRTEPFACDP 430
Query: 308 TDEP 311
+ P
Sbjct: 431 SSLP 434
>At4g22940 [D] KOG0600 Cdc2-related protein kinase
Length = 458
Score = 162 bits (410), Expect = 9e-40
Identities = 109/286 (38%), Positives = 148/286 (51%), Gaps = 20/286 (6%)
Query: 28 VGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHENLICLEDI 87
+G G F V A D L ++ VA+K+I + S K RE+ +L+ L H N+I LE +
Sbjct: 109 IGGGTFSKVFKARDLLRNKTVALKRIRFDINNSESIKCIAREIIILRKLDHPNVIKLEGL 168
Query: 88 FLSPLED--IYFVTELQGTDL---HRLLQTRPLEKQFVQYFLYQILRGLKYVHSAGVIHR 142
L + +Y + E DL LL E Q V+ ++ Q+LRGL + H+ V+HR
Sbjct: 169 MLVDHDSSTLYLIFEYMEHDLLGLSSLLGVHFSEPQ-VKCYMRQLLRGLDHCHTNHVLHR 227
Query: 143 DLKPSNILINENCDLKICDFGLARIQDPQ----MTGYVSTRYYRAPEIMLTWQKYNVEVD 198
D+K SN+LIN + LKI DFGLA DP +T +V+T +YR PE++L Y + VD
Sbjct: 228 DMKSSNLLINGDGVLKIADFGLATFFDPHNSVPLTTHVATLWYRPPELLLGASHYGIGVD 287
Query: 199 IWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLKFVTSLPHR 258
+WS GC+ E+ GKP+ PGK+ Q I L GSP D LK S P R
Sbjct: 288 LWSTGCVIGELYAGKPILPGKNETDQLHKIFKLCGSPSDDY------WTKLKLQLSTPLR 341
Query: 259 DPVPFSSR----FQNLEPDAIDLLEKMLVFDPKKRITAADALAHPY 300
P+ S F+ I LLE +L DP R TAA AL Y
Sbjct: 342 PIYPYGSHIAETFKQFPASVISLLETLLSIDPDFRGTAASALKSKY 387
>At4g10010 [D] KOG0600 Cdc2-related protein kinase
Length = 649
Score = 162 bits (410), Expect = 9e-40
Identities = 108/306 (35%), Positives = 159/306 (51%), Gaps = 23/306 (7%)
Query: 11 IFGTVFEITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKI----MKPFSTSVLAKRT 66
I G V + L+ +G G + V A D T + VA+KK+ M P S +A
Sbjct: 145 IKGWVPRRAESFEKLDKIGQGTYSSVYRARDLETGKMVAMKKVRFVNMDPESVRFMA--- 201
Query: 67 YRELKLLKHLRHENLICLEDIFLSPLE-DIYFVTELQGTDLHRLLQTRP---LEKQFVQY 122
RE+ +L+ L H N++ LE + S L +Y V E DL L RP + ++
Sbjct: 202 -REINILRKLDHPNVMKLECLVTSKLSGSLYLVFEYMEHDLSGLA-LRPGVKFTESQIKC 259
Query: 123 FLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARI----QDPQMTGYVST 178
++ Q+L GL++ HS G++HRD+K N+L+N + LKI DFGLA I QD +T V T
Sbjct: 260 YMKQLLSGLEHCHSRGILHRDIKGPNLLVNNDGVLKIGDFGLANIYHPEQDQPLTSRVVT 319
Query: 179 RYYRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKD 238
+YRAPE++L +Y +D+WS GCI E+ GKP+ PG+ V Q I GSP
Sbjct: 320 LWYRAPELLLGATEYGPGIDLWSVGCILTELFLGKPIMPGRTEVEQMHKIFKFCGSPS-- 377
Query: 239 VIDTICSENTLKFVTSLPHRDPVP--FSSRFQNLEPDAIDLLEKMLVFDPKKRITAADAL 296
D + L TS + P F+NL P A+ L++K+L +P KR TA+ L
Sbjct: 378 --DDYWQKTKLPLATSFKPQQPYKRVLLETFKNLPPSALALVDKLLSLEPAKRGTASSTL 435
Query: 297 AHPYLS 302
+ + +
Sbjct: 436 SSKFFT 441
>Hs7657498 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 419
Score = 162 bits (409), Expect = 1e-39
Identities = 93/285 (32%), Positives = 152/285 (52%), Gaps = 10/285 (3%)
Query: 22 YTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLR-HEN 80
Y + +G G F V A K++ + F S+ RE++ L+ L H N
Sbjct: 4 YKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQRFE-SIEQVNNLREIQALRRLNPHPN 62
Query: 81 LICLEDI-FLSPLEDIYFVTELQGTDLHRLLQTR--PLEKQFVQYFLYQILRGLKYVHSA 137
++ L ++ F + + EL +++ L++ R PL ++ + +++YQ+ + L ++H
Sbjct: 63 ILMLHEVVFDRKSGSLALICELMDMNIYELIRGRRYPLSEKKIMHYMYQLCKSLDHIHRN 122
Query: 138 GVIHRDLKPSNILINENCDLKICDFGLAR--IQDPQMTGYVSTRYYRAPEIMLTWQKYNV 195
G+ HRD+KP NILI ++ LK+ DFG R T Y+STR+YRAPE +LT Y
Sbjct: 123 GIFHRDVKPENILIKQDV-LKLGDFGSCRSVYSKQPYTEYISTRWYRAPECLLTDGFYTY 181
Query: 196 EVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLKFVTSL 255
++D+WSAGC+F E+ +PLFPG + + Q S I D++G+P + ++ + F
Sbjct: 182 KMDLWSAGCVFYEIASLQPLFPGVNELDQISKIHDVIGTPAQKILTKFKQSRAMNFDFPF 241
Query: 256 PHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPY 300
+P + NL P + LL M+ +DP +RI A AL HPY
Sbjct: 242 KKGSGIPLLT--TNLSPQCLSLLHAMVAYDPDERIAAHQALQHPY 284
>CE12408 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 527
Score = 162 bits (409), Expect = 1e-39
Identities = 102/287 (35%), Positives = 153/287 (52%), Gaps = 13/287 (4%)
Query: 21 RYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHEN 80
RY +G G FG V A T VAIK++ K F + A + RE+K LK L H N
Sbjct: 44 RYLMTKRLGDGTFGEVMLAKKIDTGDRVAIKRMKKKFYSWEEAM-SLREVKSLKKLNHPN 102
Query: 81 LICLEDIFLSPLEDIYFVTELQGTDLHRLLQTRP--LEKQFVQYFLYQILRGLKYVHSAG 138
+I L ++ + + +YFV E +L+ L++ R + ++ +YQ+L+GL ++H G
Sbjct: 103 IIKLREV-IRENDILYFVFEFMQENLYELMKDRDRYFPESVIRNIIYQVLQGLAFMHKNG 161
Query: 139 VIHRDLKPSNILINENCDLKICDFGLARI--QDPQMTGYVSTRYYRAPEIMLTWQKYNVE 196
HRD+KP NI+ N +KI DFGLAR P T YVSTR+YRAPEI+L YN
Sbjct: 162 FFHRDMKPENIMCNGTELVKIADFGLAREIRSKPPYTDYVSTRWYRAPEILLRSTSYNSP 221
Query: 197 VDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVID---TICSENTLKFVT 253
+D+W+ GCI AE+ +PLFPG + Q I +LG+P KD + S +F
Sbjct: 222 IDMWALGCIMAELYILRPLFPGTSEMDQLFKIISILGTPNKDEWPEGYQLASAMNFRFQQ 281
Query: 254 SLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPY 300
+ P + + + L+ M++++P+KR A +L + Y
Sbjct: 282 VV----ATPMEQVVNTISKEGMKLMMDMMLWNPEKRPNANQSLRYKY 324
>HsM4504163 [G] KOG0658 Glycogen synthase kinase-3
Length = 420
Score = 161 bits (408), Expect = 2e-39
Identities = 98/300 (32%), Positives = 165/300 (54%), Gaps = 23/300 (7%)
Query: 22 YTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHENL 81
YT+ +G G+FG+V A + + VAIKK+++ + REL++++ L H N+
Sbjct: 56 YTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQD------KRFKNRELQIMRKLDHCNI 109
Query: 82 ICLEDIFLSPLE---DIYF--VTELQGTDLHRLLQTRPLEKQ-----FVQYFLYQILRGL 131
+ L F S E ++Y V + ++R+ + KQ +V+ ++YQ+ R L
Sbjct: 110 VRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSL 169
Query: 132 KYVHSAGVIHRDLKPSNILIN-ENCDLKICDFGLAR--IQDPQMTGYVSTRYYRAPEIML 188
Y+HS G+ HRD+KP N+L++ + LK+CDFG A+ ++ Y+ +RYYRAPE++
Sbjct: 170 AYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIF 229
Query: 189 TWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENT 248
Y +D+WSAGC+ AE++ G+P+FPG V Q I +LG+P ++ I + + N
Sbjct: 230 GATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREM-NPNY 288
Query: 249 LKFVTSLPHRDPVPFSSRFQ-NLEPDAIDLLEKMLVFDPKKRITAADALAHPYLSPYHDP 307
+F P P++ F+ P+AI L ++L + P R+T +A AH + DP
Sbjct: 289 TEF--KFPQIKAHPWTKVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELRDP 346
>Hs4507281 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 1030
Score = 161 bits (407), Expect = 2e-39
Identities = 95/289 (32%), Positives = 152/289 (51%), Gaps = 9/289 (3%)
Query: 18 ITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLR 77
+ N++ L VG GA+G+V T + VAIKK + + T RELK+L+ L+
Sbjct: 9 VMNKFEILGVVGEGAYGVVLKCRHKETHEIVAIKKFKDSEENEEVKETTLRELKMLRTLK 68
Query: 78 HENLICLEDIFLSPLEDIYFVTELQGTDLHRLLQTRP--LEKQFVQYFLYQILRGLKYVH 135
EN++ L++ F + +Y V E ++ LL+ P + + V+ ++YQ+++ + + H
Sbjct: 69 QENIVELKEAFRRRGK-LYLVFEYVEKNMLELLEEMPNGVPPEKVKSYIYQLIKAIHWCH 127
Query: 136 SAGVIHRDLKPSNILINENCDLKICDFGLARI----QDPQMTGYVSTRYYRAPEIMLTWQ 191
++HRD+KP N+LI+ N LK+CDFG AR + T YV+TR+YR+PE++L
Sbjct: 128 KNDIVHRDIKPENLLISHNDVLKLCDFGFARNLSEGNNANYTEYVATRWYRSPELLL-GA 186
Query: 192 KYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLKF 251
Y VD+WS GCI E+ +G+PLFPG+ + Q I +LG P + + S
Sbjct: 187 PYGKSVDMWSVGCILGELSDGQPLFPGESEIDQLFTIQKVLGPLPSEQMKLFYSNPRFHG 246
Query: 252 VTSLPHRDPVPFSSRFQN-LEPDAIDLLEKMLVFDPKKRITAADALAHP 299
+ P R+ L +DL++ +L DP R L HP
Sbjct: 247 LRFPAVNHPQSLERRYLGILNSVLLDLMKNLLKLDPADRYLTEQCLNHP 295
>CE21401 [G] KOG0658 Glycogen synthase kinase-3
Length = 362
Score = 161 bits (407), Expect = 2e-39
Identities = 98/300 (32%), Positives = 170/300 (56%), Gaps = 23/300 (7%)
Query: 22 YTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHENL 81
Y + +G G+FG+V A + T++ VAIKK+++ + REL++++ L H N+
Sbjct: 36 YYDQKVIGNGSFGVVFLAKLSTTNEMVAIKKVLQD------KRFKNRELQIMRKLNHPNI 89
Query: 82 ICLEDIFLSPLE---DIYF--VTELQGTDLHRLLQTRPLEKQ-----FVQYFLYQILRGL 131
+ L+ F S E ++Y + E ++R+ + ++Q +V+ ++YQ+LR L
Sbjct: 90 VKLKYFFYSSGEKKDELYLNLILEYVPETVYRVARHYSKQRQQIPMIYVKLYMYQLLRSL 149
Query: 132 KYVHSAGVIHRDLKPSNILIN-ENCDLKICDFGLAR--IQDPQMTGYVSTRYYRAPEIML 188
Y+HS G+ HRD+KP N+LI+ E+ LK+CDFG A+ +++ Y+ +RYYRAPE++
Sbjct: 150 AYIHSIGICHRDIKPQNLLIDPESGVLKLCDFGSAKYLVRNEPNVSYICSRYYRAPELIF 209
Query: 189 TWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENT 248
Y +D+WSAG + AE++ G+P+FPG V Q I +LG+P ++ I ++ + N
Sbjct: 210 GATNYTNSIDVWSAGTVMAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIQSM-NPNY 268
Query: 249 LKFVTSLPHRDPVPFSSRFQNLEP-DAIDLLEKMLVFDPKKRITAADALAHPYLSPYHDP 307
+F P P++ F+ P +AIDL+ K++ + P R T A H + +P
Sbjct: 269 KEF--KFPQIKAHPWNKVFRVHTPAEAIDLISKIIEYTPTSRPTPQAACQHAFFDELRNP 326
>CE00315 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 332
Score = 161 bits (407), Expect = 2e-39
Identities = 102/297 (34%), Positives = 157/297 (52%), Gaps = 21/297 (7%)
Query: 20 NRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHE 79
N +T L +G G +G+V + T+ VA+KKI + RE+ LLK L+H
Sbjct: 20 NDFTKLEKIGEGTYGVVYKGKNRRTNAMVAMKKIRLESEDEGVPSTAVREISLLKELQHP 79
Query: 80 NLICLEDIFLSPLEDIYFVTELQGTDLHRLL------QTRPLEKQFVQYFLYQILRGLKY 133
N++ LE + + ++ + E DL R + + PLE ++ + +QIL+ + +
Sbjct: 80 NVVGLEAVIMQE-NRLFLIFEFLSFDLKRYMDQLGKDEYLPLET--LKSYTFQILQAMCF 136
Query: 134 VHSAGVIHRDLKPSNILINENCDLKICDFGLAR---IQDPQMTGYVSTRYYRAPEIMLTW 190
H VIHRDLKP N+L++ N +K+ DFGLAR I T V T +YRAPEI++
Sbjct: 137 CHQRRVIHRDLKPQNLLVDNNGAIKLADFGLARAIGIPIRVYTHEVVTLWYRAPEILMGA 196
Query: 191 QKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLK 250
Q+Y++ VD+WS GCIFAEM KPLF G + + I +LG+P + ++ E+
Sbjct: 197 QRYSMGVDMWSIGCIFAEMATKKPLFQGDSEIDELFRIFRVLGTPTE--LEWNGVESLPD 254
Query: 251 FVTSLPHRDPVPFSSRFQN-------LEPDAIDLLEKMLVFDPKKRITAADALAHPY 300
+ + P +F + L+ A LLE +L++DP R+ A AL HPY
Sbjct: 255 YKATFPKWRENFLRDKFYDKKTGKHLLDDTAFSLLEGLLIYDPSLRLNAKKALVHPY 311
>7290342 [G] KOG0658 Glycogen synthase kinase-3
Length = 1008
Score = 161 bits (407), Expect = 2e-39
Identities = 98/293 (33%), Positives = 161/293 (54%), Gaps = 23/293 (7%)
Query: 22 YTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHENL 81
YT+ +G G+FG+V A T + VAIKK+++ + REL++++ L H N+
Sbjct: 548 YTDTKVIGNGSFGVVFQAKLCDTGELVAIKKVLQD------RRFKNRELQIMRKLEHCNI 601
Query: 82 ICLEDIFLSPLED-----IYFVTELQGTDLHRLLQTRPLEKQ-----FVQYFLYQILRGL 131
+ L F S E + V E ++++ + KQ F++ ++YQ+ R L
Sbjct: 602 VKLLYFFYSSGEKRDEVFLNLVLEYIPETVYKVARQYAKTKQTIPINFIRLYMYQLFRSL 661
Query: 132 KYVHSAGVIHRDLKPSNILIN-ENCDLKICDFGLAR--IQDPQMTGYVSTRYYRAPEIML 188
Y+HS G+ HRD+KP N+L++ E LK+CDFG A+ + Y+ +RYYRAPE++
Sbjct: 662 AYIHSLGICHRDIKPQNLLLDPETAVLKLCDFGSAKQLLHGEPNVSYICSRYYRAPELIF 721
Query: 189 TWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENT 248
Y ++D+WSAGC+ AE++ G+P+FPG V Q + +LG+P ++ I + + N
Sbjct: 722 GAINYTTKIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEVIKVLGTPTREQIREM-NPNY 780
Query: 249 LKFVTSLPHRDPVPFSSRFQNLEP-DAIDLLEKMLVFDPKKRITAADALAHPY 300
+F P P+ F+ P +AI+L+ +L + P RIT A AHP+
Sbjct: 781 TEF--KFPQIKSHPWQKVFRIRTPTEAINLVSLLLEYTPSARITPLKACAHPF 831
>SPBC19F8.07 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 335
Score = 160 bits (406), Expect = 3e-39
Identities = 103/301 (34%), Positives = 158/301 (52%), Gaps = 10/301 (3%)
Query: 22 YTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHENL 81
Y VG G + +V T++ VAIKKI + RE+K L+ RH+N+
Sbjct: 11 YVKERKVGEGTYAVVFLGRQKETNRRVAIKKIKVGQFKDGIDISALREIKFLRESRHDNV 70
Query: 82 ICLEDIFLSPLEDIYFVTELQGTDLHRLLQTRPLEKQ--FVQYFLYQILRGLKYVHSAGV 139
I L D+F S ++ + E +DL L++ + + Q ++ ++ +LRGL ++HS +
Sbjct: 71 IELVDVF-STKSNLNIILEFLDSDLEMLIKDKFIVFQPAHIKSWMVMLLRGLHHIHSRFI 129
Query: 140 IHRDLKPSNILINENCDLKICDFGLARI--QDPQMTGYVSTRYYRAPEIMLTWQKYNVEV 197
+HRDLKP+N+LI+ + LK+ DFGL+R M+ V TR+YR PE+ + + Y V
Sbjct: 130 LHRDLKPNNLLISSDGVLKLADFGLSRDFGTPSHMSHQVITRWYRPPELFMGCRSYGTGV 189
Query: 198 DIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLKFVTSLPH 257
D+WS GCIFAE++ P PG+ + Q ++I LG+P +VI S L + H
Sbjct: 190 DMWSVGCIFAELMLRTPYLPGESDLDQLNVIFRALGTPEPEVIK---SMQQLPNYVEMKH 246
Query: 258 RDPV--PFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPYLSPYHDPTDEPIAEA 315
P + F + IDLL+ ML ++P +R TA AL H Y S PT +
Sbjct: 247 IPPPNGGMEALFSAAGHEEIDLLKMMLDYNPYRRPTAQQALEHHYFSALPKPTHPSLLPR 306
Query: 316 K 316
K
Sbjct: 307 K 307
>At4g19110 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 256
Score = 160 bits (406), Expect = 3e-39
Identities = 87/240 (36%), Positives = 146/240 (60%), Gaps = 13/240 (5%)
Query: 68 RELKLLKHLRHENLICLEDIFLSPLEDIYFVTELQGTDLHRLLQTRPLEKQF----VQYF 123
RE+K L+ + H N++ L+++ + + +YFV E +L++L++ R +K F ++ +
Sbjct: 15 REVKSLRRMNHPNIVKLKEV-IRENDILYFVFEYMECNLYQLMKDR--QKLFAEADIKNW 71
Query: 124 LYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARI--QDPQMTGYVSTRYY 181
+Q+ +GL Y+H G HRDLKP N+L++++ +KI DFGLAR P T YVSTR+Y
Sbjct: 72 CFQVFQGLSYMHQRGYFHRDLKPENLLVSKDI-IKIADFGLAREVNSSPPFTEYVSTRWY 130
Query: 182 RAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDV-I 240
RAPE++L Y +VD+W+ G I AE++ +P+FPG + I ++G+P ++ +
Sbjct: 131 RAPEVLLQSYVYTSKVDMWAMGAIMAELLSLRPIFPGASEADEIYKICSVIGTPTEETWL 190
Query: 241 DTICSENTLKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPY 300
+ + NT+ + P VP SS + DAI+L+E++ +DP R TAA+ L HP+
Sbjct: 191 EGLNLANTINY--QFPQLPGVPLSSLMPSASEDAINLIERLCSWDPSSRPTAAEVLQHPF 248
>7303051 [UT] KOG0662 Cyclin-dependent kinase CDK5
Length = 294
Score = 160 bits (406), Expect = 3e-39
Identities = 98/288 (34%), Positives = 155/288 (53%), Gaps = 9/288 (3%)
Query: 21 RYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHEN 80
+Y + +G G +G V + T + VA+K++ + RE+ LLK L+H+N
Sbjct: 3 KYDKMEKIGEGTYGTVFKGRNRDTMEIVALKRVRLDEDDEGVPSSALREICLLKELKHKN 62
Query: 81 LICLEDIFLSPLEDIYFVTELQGTDLHRLLQTR--PLEKQFVQYFLYQILRGLKYVHSAG 138
++ L D+ S + + V E DL + + ++ + F+ Q+LRGL + HS
Sbjct: 63 IVRLIDVLHSD-KKLTLVFEHCDQDLKKYFDSLNGEIDMAVCRSFMLQLLRGLAFCHSHN 121
Query: 139 VIHRDLKPSNILINENCDLKICDFGLARIQDPQMTGY---VSTRYYRAPEIMLTWQKYNV 195
V+HRDLKP N+LIN+N +LK+ DFGLAR + Y V T +YR P+++ + Y
Sbjct: 122 VLHRDLKPQNLLINKNGELKLADFGLARAFGIPVKCYSAEVVTLWYRPPDVLFGAKLYTT 181
Query: 196 EVDIWSAGCIFAEMIE-GKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLKFVTS 254
+D+WSAGCI AE+ + G+PLFPG D + Q I +LG+P +D + + + S
Sbjct: 182 SIDMWSAGCILAELADAGRPLFPGSDVLDQLMKIFRVLGTPNEDSWPGVSHLSDYVALPS 241
Query: 255 LPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPYLS 302
P +S L DLL+K+L+ P +RI+A A+ HPY +
Sbjct: 242 FP--AITSWSQLVPRLNSKGRDLLQKLLICRPNQRISAEAAMQHPYFT 287
>CE21213 [UT] KOG0662 Cyclin-dependent kinase CDK5
Length = 292
Score = 160 bits (404), Expect = 5e-39
Identities = 104/298 (34%), Positives = 152/298 (50%), Gaps = 23/298 (7%)
Query: 22 YTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHENL 81
Y + +G G +G V A + + + VA+K++ + RE+ +L+ L+H N+
Sbjct: 4 YDKMEKIGEGTYGTVFKARNKNSGEIVALKRVRLDDDDEGVPSSALREICILRELKHRNV 63
Query: 82 ICLEDIFLSPLEDIYFVTELQGTDLHRLLQTRP--LEKQFVQYFLYQILRGLKYVHSAGV 139
+ L D+ S + V E DL + + ++ Q + + Q+LRGL + H+ V
Sbjct: 64 VRLYDVVHSE-NKLTLVFEYCDQDLKKFFDSLNGYMDAQTARSLMLQLLRGLSFCHAHHV 122
Query: 140 IHRDLKPSNILINENCDLKICDFGLAR---IQDPQMTGYVSTRYYRAPEIMLTWQKYNVE 196
+HRDLKP N+LIN N LK+ DFGLAR + + V T +YR P+++ + YN
Sbjct: 123 LHRDLKPQNLLINTNGTLKLADFGLARAFGVPVRCFSAEVVTLWYRPPDVLFGAKLYNTS 182
Query: 197 VDIWSAGCIFAEMIE-GKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLKFVTSL 255
+D+WSAGCIFAE+ G+PLFPG D Q I LGSP SE+ +T L
Sbjct: 183 IDMWSAGCIFAEISNAGRPLFPGADVDDQLKRIFKQLGSP---------SEDNWPSITQL 233
Query: 256 PHRDPVP-------FSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPYLSPYHD 306
P P P +S NL DLL+K+LV +P RI A AL H Y + D
Sbjct: 234 PDYKPYPIYHPTLTWSQIVPNLNSRGRDLLQKLLVCNPAGRIDADAALRHAYFADTSD 291
>At1g53050 [D] KOG0600 Cdc2-related protein kinase
Length = 694
Score = 159 bits (403), Expect = 6e-39
Identities = 110/310 (35%), Positives = 161/310 (51%), Gaps = 17/310 (5%)
Query: 11 IFGTVFEITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKI----MKPFSTSVLAKRT 66
I G V + + L+ +G G + V A D + VA+KK+ ++P S +A
Sbjct: 123 IRGWVPRRADSFEKLDKIGQGTYSNVYRARDLDQKKIVALKKVRFDNLEPESVRFMA--- 179
Query: 67 YRELKLLKHLRHENLICLEDIFLSPLE-DIYFVTELQGTDLHRLLQTRPLE--KQFVQYF 123
RE+++L+ L H N+I LE + S + +Y V E DL L ++ + V+ +
Sbjct: 180 -REIQILRRLDHPNIIKLEGLVTSRMSCSLYLVFEYMEHDLAGLASHPAIKFSESQVKCY 238
Query: 124 LYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQ----MTGYVSTR 179
L Q+L GL + HS GV+HRD+K SN+LI+ + LKI DFGLA DP+ +T V T
Sbjct: 239 LQQLLHGLDHCHSRGVLHRDIKGSNLLIDNSGVLKIADFGLASFFDPRQTQPLTSRVVTL 298
Query: 180 YYRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDV 239
+YR PE++L +Y VD+WSAGCI AE+ GKP+ PG+ V Q I L GSP +D
Sbjct: 299 WYRPPELLLGATRYGAAVDLWSAGCILAELYAGKPIMPGRTEVEQLHKIFKLCGSPTEDY 358
Query: 240 IDTICSENTLKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHP 299
+ F + P++ V F+ A+ LLE +L +P R TA AL
Sbjct: 359 WVKSRLPHATIFKPTQPYKRLV--GETFKEFPQPALALLETLLSVNPDDRGTATAALKSE 416
Query: 300 YLSPYHDPTD 309
+ S P D
Sbjct: 417 FFSTRPLPCD 426
>Hs16357496 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 439
Score = 159 bits (402), Expect = 8e-39
Identities = 100/295 (33%), Positives = 158/295 (52%), Gaps = 14/295 (4%)
Query: 25 LNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHENLICL 84
LN + G +G+V A D T + VA+K++ + RE+ + +H N++ +
Sbjct: 85 LNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTV 144
Query: 85 EDIFL-SPLEDIYFVTELQGTDLHRLLQT--RPLEKQFVQYFLYQILRGLKYVHSAGVIH 141
+I + S ++ IY V DL L++T +P V+ + Q+LRG+K++H ++H
Sbjct: 145 REIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILH 204
Query: 142 RDLKPSNILINENCDLKICDFGLARIQDPQMTGY---VSTRYYRAPEIMLTWQKYNVEVD 198
RDLK SN+L++ LK+ DFGLAR + Y V T +YRAPE++L ++Y+ VD
Sbjct: 205 RDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYSTAVD 264
Query: 199 IWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLKFVTSLPHR 258
+WS GCIF E++ KPLFPGK + Q + + LG+P + + +K +T H
Sbjct: 265 MWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKMTFSEH- 323
Query: 259 DPVPFSS---RFQNLEPD-AIDLLEKMLVFDPKKRITAADALAHPYLSPYHDPTD 309
P+++ RF L D DL+ K L + P +RI+A D L H Y P D
Sbjct: 324 ---PYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPID 375
>Hs16332372 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 771
Score = 159 bits (402), Expect = 8e-39
Identities = 100/295 (33%), Positives = 158/295 (52%), Gaps = 14/295 (4%)
Query: 25 LNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHENLICL 84
LN + G +G+V A D T + VA+K++ + RE+ + +H N++ +
Sbjct: 417 LNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTV 476
Query: 85 EDIFL-SPLEDIYFVTELQGTDLHRLLQT--RPLEKQFVQYFLYQILRGLKYVHSAGVIH 141
+I + S ++ IY V DL L++T +P V+ + Q+LRG+K++H ++H
Sbjct: 477 REIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILH 536
Query: 142 RDLKPSNILINENCDLKICDFGLARIQDPQMTGY---VSTRYYRAPEIMLTWQKYNVEVD 198
RDLK SN+L++ LK+ DFGLAR + Y V T +YRAPE++L ++Y+ VD
Sbjct: 537 RDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYSTAVD 596
Query: 199 IWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLKFVTSLPHR 258
+WS GCIF E++ KPLFPGK + Q + + LG+P + + +K +T H
Sbjct: 597 MWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKMTFSEH- 655
Query: 259 DPVPFSS---RFQNLEPD-AIDLLEKMLVFDPKKRITAADALAHPYLSPYHDPTD 309
P+++ RF L D DL+ K L + P +RI+A D L H Y P D
Sbjct: 656 ---PYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPID 707
>Hs16332370 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 780
Score = 159 bits (402), Expect = 8e-39
Identities = 100/295 (33%), Positives = 158/295 (52%), Gaps = 14/295 (4%)
Query: 25 LNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHENLICL 84
LN + G +G+V A D T + VA+K++ + RE+ + +H N++ +
Sbjct: 426 LNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTV 485
Query: 85 EDIFL-SPLEDIYFVTELQGTDLHRLLQT--RPLEKQFVQYFLYQILRGLKYVHSAGVIH 141
+I + S ++ IY V DL L++T +P V+ + Q+LRG+K++H ++H
Sbjct: 486 REIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILH 545
Query: 142 RDLKPSNILINENCDLKICDFGLARIQDPQMTGY---VSTRYYRAPEIMLTWQKYNVEVD 198
RDLK SN+L++ LK+ DFGLAR + Y V T +YRAPE++L ++Y+ VD
Sbjct: 546 RDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYSTAVD 605
Query: 199 IWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLKFVTSLPHR 258
+WS GCIF E++ KPLFPGK + Q + + LG+P + + +K +T H
Sbjct: 606 MWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKMTFSEH- 664
Query: 259 DPVPFSS---RFQNLEPD-AIDLLEKMLVFDPKKRITAADALAHPYLSPYHDPTD 309
P+++ RF L D DL+ K L + P +RI+A D L H Y P D
Sbjct: 665 ---PYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPID 716
>Hs16332368 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 461
Score = 159 bits (402), Expect = 8e-39
Identities = 100/295 (33%), Positives = 158/295 (52%), Gaps = 14/295 (4%)
Query: 25 LNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHENLICL 84
LN + G +G+V A D T + VA+K++ + RE+ + +H N++ +
Sbjct: 107 LNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTV 166
Query: 85 EDIFL-SPLEDIYFVTELQGTDLHRLLQT--RPLEKQFVQYFLYQILRGLKYVHSAGVIH 141
+I + S ++ IY V DL L++T +P V+ + Q+LRG+K++H ++H
Sbjct: 167 REIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILH 226
Query: 142 RDLKPSNILINENCDLKICDFGLARIQDPQMTGY---VSTRYYRAPEIMLTWQKYNVEVD 198
RDLK SN+L++ LK+ DFGLAR + Y V T +YRAPE++L ++Y+ VD
Sbjct: 227 RDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYSTAVD 286
Query: 199 IWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLKFVTSLPHR 258
+WS GCIF E++ KPLFPGK + Q + + LG+P + + +K +T H
Sbjct: 287 MWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKMTFSEH- 345
Query: 259 DPVPFSS---RFQNLEPD-AIDLLEKMLVFDPKKRITAADALAHPYLSPYHDPTD 309
P+++ RF L D DL+ K L + P +RI+A D L H Y P D
Sbjct: 346 ---PYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPID 397
>Hs16332366 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 565
Score = 159 bits (402), Expect = 8e-39
Identities = 100/295 (33%), Positives = 158/295 (52%), Gaps = 14/295 (4%)
Query: 25 LNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHENLICL 84
LN + G +G+V A D T + VA+K++ + RE+ + +H N++ +
Sbjct: 211 LNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTV 270
Query: 85 EDIFL-SPLEDIYFVTELQGTDLHRLLQT--RPLEKQFVQYFLYQILRGLKYVHSAGVIH 141
+I + S ++ IY V DL L++T +P V+ + Q+LRG+K++H ++H
Sbjct: 271 REIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILH 330
Query: 142 RDLKPSNILINENCDLKICDFGLARIQDPQMTGY---VSTRYYRAPEIMLTWQKYNVEVD 198
RDLK SN+L++ LK+ DFGLAR + Y V T +YRAPE++L ++Y+ VD
Sbjct: 331 RDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYSTAVD 390
Query: 199 IWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLKFVTSLPHR 258
+WS GCIF E++ KPLFPGK + Q + + LG+P + + +K +T H
Sbjct: 391 MWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKMTFSEH- 449
Query: 259 DPVPFSS---RFQNLEPD-AIDLLEKMLVFDPKKRITAADALAHPYLSPYHDPTD 309
P+++ RF L D DL+ K L + P +RI+A D L H Y P D
Sbjct: 450 ---PYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPID 501
>Hs16332364 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 748
Score = 159 bits (402), Expect = 8e-39
Identities = 100/295 (33%), Positives = 158/295 (52%), Gaps = 14/295 (4%)
Query: 25 LNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHENLICL 84
LN + G +G+V A D T + VA+K++ + RE+ + +H N++ +
Sbjct: 394 LNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTV 453
Query: 85 EDIFL-SPLEDIYFVTELQGTDLHRLLQT--RPLEKQFVQYFLYQILRGLKYVHSAGVIH 141
+I + S ++ IY V DL L++T +P V+ + Q+LRG+K++H ++H
Sbjct: 454 REIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILH 513
Query: 142 RDLKPSNILINENCDLKICDFGLARIQDPQMTGY---VSTRYYRAPEIMLTWQKYNVEVD 198
RDLK SN+L++ LK+ DFGLAR + Y V T +YRAPE++L ++Y+ VD
Sbjct: 514 RDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYSTAVD 573
Query: 199 IWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLKFVTSLPHR 258
+WS GCIF E++ KPLFPGK + Q + + LG+P + + +K +T H
Sbjct: 574 MWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKMTFSEH- 632
Query: 259 DPVPFSS---RFQNLEPD-AIDLLEKMLVFDPKKRITAADALAHPYLSPYHDPTD 309
P+++ RF L D DL+ K L + P +RI+A D L H Y P D
Sbjct: 633 ---PYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPID 684
>Hs16332362 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 737
Score = 159 bits (402), Expect = 8e-39
Identities = 100/295 (33%), Positives = 158/295 (52%), Gaps = 14/295 (4%)
Query: 25 LNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHENLICL 84
LN + G +G+V A D T + VA+K++ + RE+ + +H N++ +
Sbjct: 383 LNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTV 442
Query: 85 EDIFL-SPLEDIYFVTELQGTDLHRLLQT--RPLEKQFVQYFLYQILRGLKYVHSAGVIH 141
+I + S ++ IY V DL L++T +P V+ + Q+LRG+K++H ++H
Sbjct: 443 REIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILH 502
Query: 142 RDLKPSNILINENCDLKICDFGLARIQDPQMTGY---VSTRYYRAPEIMLTWQKYNVEVD 198
RDLK SN+L++ LK+ DFGLAR + Y V T +YRAPE++L ++Y+ VD
Sbjct: 503 RDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYSTAVD 562
Query: 199 IWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLKFVTSLPHR 258
+WS GCIF E++ KPLFPGK + Q + + LG+P + + +K +T H
Sbjct: 563 MWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKMTFSEH- 621
Query: 259 DPVPFSS---RFQNLEPD-AIDLLEKMLVFDPKKRITAADALAHPYLSPYHDPTD 309
P+++ RF L D DL+ K L + P +RI+A D L H Y P D
Sbjct: 622 ---PYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPID 673
>Hs16332360 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 526
Score = 159 bits (402), Expect = 8e-39
Identities = 100/295 (33%), Positives = 158/295 (52%), Gaps = 14/295 (4%)
Query: 25 LNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHENLICL 84
LN + G +G+V A D T + VA+K++ + RE+ + +H N++ +
Sbjct: 172 LNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTV 231
Query: 85 EDIFL-SPLEDIYFVTELQGTDLHRLLQT--RPLEKQFVQYFLYQILRGLKYVHSAGVIH 141
+I + S ++ IY V DL L++T +P V+ + Q+LRG+K++H ++H
Sbjct: 232 REIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILH 291
Query: 142 RDLKPSNILINENCDLKICDFGLARIQDPQMTGY---VSTRYYRAPEIMLTWQKYNVEVD 198
RDLK SN+L++ LK+ DFGLAR + Y V T +YRAPE++L ++Y+ VD
Sbjct: 292 RDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYSTAVD 351
Query: 199 IWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLKFVTSLPHR 258
+WS GCIF E++ KPLFPGK + Q + + LG+P + + +K +T H
Sbjct: 352 MWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKMTFSEH- 410
Query: 259 DPVPFSS---RFQNLEPD-AIDLLEKMLVFDPKKRITAADALAHPYLSPYHDPTD 309
P+++ RF L D DL+ K L + P +RI+A D L H Y P D
Sbjct: 411 ---PYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPID 462
>Hs16332358 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 782
Score = 159 bits (402), Expect = 8e-39
Identities = 100/295 (33%), Positives = 158/295 (52%), Gaps = 14/295 (4%)
Query: 25 LNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHENLICL 84
LN + G +G+V A D T + VA+K++ + RE+ + +H N++ +
Sbjct: 428 LNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTV 487
Query: 85 EDIFL-SPLEDIYFVTELQGTDLHRLLQT--RPLEKQFVQYFLYQILRGLKYVHSAGVIH 141
+I + S ++ IY V DL L++T +P V+ + Q+LRG+K++H ++H
Sbjct: 488 REIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILH 547
Query: 142 RDLKPSNILINENCDLKICDFGLARIQDPQMTGY---VSTRYYRAPEIMLTWQKYNVEVD 198
RDLK SN+L++ LK+ DFGLAR + Y V T +YRAPE++L ++Y+ VD
Sbjct: 548 RDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYSTAVD 607
Query: 199 IWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLKFVTSLPHR 258
+WS GCIF E++ KPLFPGK + Q + + LG+P + + +K +T H
Sbjct: 608 MWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKMTFSEH- 666
Query: 259 DPVPFSS---RFQNLEPD-AIDLLEKMLVFDPKKRITAADALAHPYLSPYHDPTD 309
P+++ RF L D DL+ K L + P +RI+A D L H Y P D
Sbjct: 667 ---PYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPID 718
>Hs10835055 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 795
Score = 159 bits (402), Expect = 8e-39
Identities = 100/295 (33%), Positives = 158/295 (52%), Gaps = 14/295 (4%)
Query: 25 LNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHENLICL 84
LN + G +G+V A D T + VA+K++ + RE+ + +H N++ +
Sbjct: 441 LNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTV 500
Query: 85 EDIFL-SPLEDIYFVTELQGTDLHRLLQT--RPLEKQFVQYFLYQILRGLKYVHSAGVIH 141
+I + S ++ IY V DL L++T +P V+ + Q+LRG+K++H ++H
Sbjct: 501 REIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILH 560
Query: 142 RDLKPSNILINENCDLKICDFGLARIQDPQMTGY---VSTRYYRAPEIMLTWQKYNVEVD 198
RDLK SN+L++ LK+ DFGLAR + Y V T +YRAPE++L ++Y+ VD
Sbjct: 561 RDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYSTAVD 620
Query: 199 IWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLKFVTSLPHR 258
+WS GCIF E++ KPLFPGK + Q + + LG+P + + +K +T H
Sbjct: 621 MWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKMTFSEH- 679
Query: 259 DPVPFSS---RFQNLEPD-AIDLLEKMLVFDPKKRITAADALAHPYLSPYHDPTD 309
P+++ RF L D DL+ K L + P +RI+A D L H Y P D
Sbjct: 680 ---PYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPID 731
>At1g18670 [D] KOG0600 Cdc2-related protein kinase
Length = 662
Score = 159 bits (402), Expect = 8e-39
Identities = 107/317 (33%), Positives = 166/317 (51%), Gaps = 19/317 (5%)
Query: 11 IFGTVFEITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKI----MKPFSTSVLAKRT 66
I G V ++ + L +G G + V A +T T + VA+KK+ +P S +A
Sbjct: 120 IHGWVPFRSDAFEKLEKIGQGTYSSVFRARETETGRIVALKKVRFDNFEPESVRFMA--- 176
Query: 67 YRELKLLKHLRHENLICLEDIFLSPLE-DIYFVTELQGTDLHRLLQTRPLE--KQFVQYF 123
RE+ +L+ L H N+I LE I S L I+ V E DL LL + ++ ++ +
Sbjct: 177 -REILILRKLNHPNIIKLEGIVTSKLSCSIHLVFEYMEHDLTGLLSSPDIDFTTPQIKCY 235
Query: 124 LYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQ-----MTGYVST 178
+ Q+L GL + H+ GV+HRD+K SN+L+N LK+ DFGLA + +T V T
Sbjct: 236 MKQLLSGLDHCHARGVMHRDIKGSNLLVNNEGILKVADFGLANFCNASGNKQPLTSRVVT 295
Query: 179 RYYRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKD 238
+YR PE++L +Y VD+WS GC+FAE++ GKP+ G+ V Q I L GSPP+D
Sbjct: 296 LWYRPPELLLGATEYGASVDLWSVGCVFAELLIGKPVLQGRTEVEQLHKIFKLCGSPPED 355
Query: 239 VIDTICSENTLKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAH 298
+ + F + + + + + L I+L+E +L P KR TA+ AL
Sbjct: 356 YWKKSKLPHAMLFKPQQHYDGCLRETLKLKGLSDADINLIETLLSIQPHKRGTASTALVS 415
Query: 299 PYLS--PYH-DPTDEPI 312
Y + P+ DP+ P+
Sbjct: 416 QYFTSKPFACDPSSLPV 432
>At1g09600 [D] KOG0600 Cdc2-related protein kinase
Length = 714
Score = 159 bits (402), Expect = 8e-39
Identities = 109/315 (34%), Positives = 164/315 (51%), Gaps = 20/315 (6%)
Query: 11 IFGTVFEITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKI----MKPFSTSVLAKRT 66
I G + + + L +G G + V A D T+Q VA+KK+ M P S +A
Sbjct: 152 INGWIPRKADSFEKLEKIGQGTYSSVYKARDLETNQLVALKKVRFANMDPDSVRFMA--- 208
Query: 67 YRELKLLKHLRHENLICLEDIFLSPLE-DIYFVTELQGTDLHRLLQTRPLE--KQFVQYF 123
RE+ +L+ L H N++ LE + S + +Y + E DL L T + + ++ +
Sbjct: 209 -REIIILRRLDHPNVMKLEGLITSRVSGSMYLIFEYMEHDLAGLASTPGINFSEAQIKCY 267
Query: 124 LYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARI----QDPQMTGYVSTR 179
+ Q+L GL++ HS GV+HRD+K SN+L++ N +LKI DFGLA Q +T V T
Sbjct: 268 MKQLLHGLEHCHSRGVLHRDIKGSNLLLDHNNNLKIGDFGLANFYQGHQKQPLTSRVVTL 327
Query: 180 YYRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDV 239
+YR PE++L Y V VD+WS GCI AE+ GKP+ PG+ V Q I L GSP ++
Sbjct: 328 WYRPPELLLGSTDYGVTVDLWSTGCILAELFTGKPIMPGRTEVEQLHKIFKLCGSPSEEY 387
Query: 240 IDTICSENTLKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHP 299
+ F P++ V + F++L A+ L+E +L +P R T A AL
Sbjct: 388 WKISKLPHATIFKPQQPYKRCV--AETFKSLPSSALALVEVLLAVEPDARGTTASALESE 445
Query: 300 YL--SPY-HDPTDEP 311
+ SP DP+ P
Sbjct: 446 FFTTSPLASDPSSLP 460
>Hs22051130 [G] KOG0658 Glycogen synthase kinase-3
Length = 483
Score = 159 bits (401), Expect = 1e-38
Identities = 99/293 (33%), Positives = 159/293 (53%), Gaps = 23/293 (7%)
Query: 22 YTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHENL 81
YT++ +G G+FG+V A T + VAIKK+++ + REL++++ L H N+
Sbjct: 119 YTDIKVIGNGSFGVVYQARLAETRELVAIKKVLQD------KRFKNRELQIMRKLDHCNI 172
Query: 82 ICLEDIFLSPLE---DIYF--VTELQGTDLHRLLQTRPLEKQ-----FVQYFLYQILRGL 131
+ L F S E ++Y V E ++R+ + K +V+ ++YQ+ R L
Sbjct: 173 VRLRYFFYSSGEKKDELYLNLVLEYVPETVYRVARHFTKAKLTIPILYVKVYMYQLFRSL 232
Query: 132 KYVHSAGVIHRDLKPSNILIN-ENCDLKICDFGLAR--IQDPQMTGYVSTRYYRAPEIML 188
Y+HS GV HRD+KP N+L++ + LK+CDFG A+ ++ Y+ +RYYRAPE++
Sbjct: 233 AYIHSQGVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIF 292
Query: 189 TWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENT 248
Y +D+WSAGC+ AE++ G+P+FPG V Q I +LG+P ++ I + T
Sbjct: 293 GATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYT 352
Query: 249 -LKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPY 300
KF H F SR P+AI L +L + P R++ +A AH +
Sbjct: 353 EFKFPQIKAHPWTKVFKSR---TPPEAIALCSSLLEYTPSSRLSPLEACAHSF 402
>Hs16357498 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 777
Score = 159 bits (401), Expect = 1e-38
Identities = 99/295 (33%), Positives = 158/295 (53%), Gaps = 14/295 (4%)
Query: 25 LNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHENLICL 84
LN + G +G+V A D T + VA+K++ + RE+ + +H N++ +
Sbjct: 423 LNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTV 482
Query: 85 EDIFL-SPLEDIYFVTELQGTDLHRLLQT--RPLEKQFVQYFLYQILRGLKYVHSAGVIH 141
+I + S ++ IY V DL L++T +P V+ + Q+LRG+K++H ++H
Sbjct: 483 REIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILH 542
Query: 142 RDLKPSNILINENCDLKICDFGLARIQDPQMTGY---VSTRYYRAPEIMLTWQKYNVEVD 198
RDLK SN+L++ LK+ DFGLAR + Y V T++YRAPE++L ++Y+ VD
Sbjct: 543 RDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVD 602
Query: 199 IWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLKFVTSLPHR 258
+WS GCIF E++ KPLFPG + Q + + LG+P + + +K +T H
Sbjct: 603 MWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSEH- 661
Query: 259 DPVPFSS---RFQNLEPD-AIDLLEKMLVFDPKKRITAADALAHPYLSPYHDPTD 309
P+++ RF L D DL+ K L + P +RI+A D L H Y P D
Sbjct: 662 ---PYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPID 713
>Hs16357486 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 780
Score = 159 bits (401), Expect = 1e-38
Identities = 99/295 (33%), Positives = 158/295 (53%), Gaps = 14/295 (4%)
Query: 25 LNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHENLICL 84
LN + G +G+V A D T + VA+K++ + RE+ + +H N++ +
Sbjct: 426 LNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTV 485
Query: 85 EDIFL-SPLEDIYFVTELQGTDLHRLLQT--RPLEKQFVQYFLYQILRGLKYVHSAGVIH 141
+I + S ++ IY V DL L++T +P V+ + Q+LRG+K++H ++H
Sbjct: 486 REIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILH 545
Query: 142 RDLKPSNILINENCDLKICDFGLARIQDPQMTGY---VSTRYYRAPEIMLTWQKYNVEVD 198
RDLK SN+L++ LK+ DFGLAR + Y V T++YRAPE++L ++Y+ VD
Sbjct: 546 RDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVD 605
Query: 199 IWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLKFVTSLPHR 258
+WS GCIF E++ KPLFPG + Q + + LG+P + + +K +T H
Sbjct: 606 MWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSEH- 664
Query: 259 DPVPFSS---RFQNLEPD-AIDLLEKMLVFDPKKRITAADALAHPYLSPYHDPTD 309
P+++ RF L D DL+ K L + P +RI+A D L H Y P D
Sbjct: 665 ---PYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPID 716
>Hs16357484 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 767
Score = 159 bits (401), Expect = 1e-38
Identities = 99/295 (33%), Positives = 158/295 (53%), Gaps = 14/295 (4%)
Query: 25 LNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHENLICL 84
LN + G +G+V A D T + VA+K++ + RE+ + +H N++ +
Sbjct: 413 LNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTV 472
Query: 85 EDIFL-SPLEDIYFVTELQGTDLHRLLQT--RPLEKQFVQYFLYQILRGLKYVHSAGVIH 141
+I + S ++ IY V DL L++T +P V+ + Q+LRG+K++H ++H
Sbjct: 473 REIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILH 532
Query: 142 RDLKPSNILINENCDLKICDFGLARIQDPQMTGY---VSTRYYRAPEIMLTWQKYNVEVD 198
RDLK SN+L++ LK+ DFGLAR + Y V T++YRAPE++L ++Y+ VD
Sbjct: 533 RDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVD 592
Query: 199 IWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLKFVTSLPHR 258
+WS GCIF E++ KPLFPG + Q + + LG+P + + +K +T H
Sbjct: 593 MWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSEH- 651
Query: 259 DPVPFSS---RFQNLEPD-AIDLLEKMLVFDPKKRITAADALAHPYLSPYHDPTD 309
P+++ RF L D DL+ K L + P +RI+A D L H Y P D
Sbjct: 652 ---PYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPID 703
>Hs16357482 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 776
Score = 159 bits (401), Expect = 1e-38
Identities = 99/295 (33%), Positives = 158/295 (53%), Gaps = 14/295 (4%)
Query: 25 LNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHENLICL 84
LN + G +G+V A D T + VA+K++ + RE+ + +H N++ +
Sbjct: 422 LNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTV 481
Query: 85 EDIFL-SPLEDIYFVTELQGTDLHRLLQT--RPLEKQFVQYFLYQILRGLKYVHSAGVIH 141
+I + S ++ IY V DL L++T +P V+ + Q+LRG+K++H ++H
Sbjct: 482 REIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILH 541
Query: 142 RDLKPSNILINENCDLKICDFGLARIQDPQMTGY---VSTRYYRAPEIMLTWQKYNVEVD 198
RDLK SN+L++ LK+ DFGLAR + Y V T++YRAPE++L ++Y+ VD
Sbjct: 542 RDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVD 601
Query: 199 IWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLKFVTSLPHR 258
+WS GCIF E++ KPLFPG + Q + + LG+P + + +K +T H
Sbjct: 602 MWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSEH- 660
Query: 259 DPVPFSS---RFQNLEPD-AIDLLEKMLVFDPKKRITAADALAHPYLSPYHDPTD 309
P+++ RF L D DL+ K L + P +RI+A D L H Y P D
Sbjct: 661 ---PYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPID 712
>Hs16357480 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 397
Score = 159 bits (401), Expect = 1e-38
Identities = 99/295 (33%), Positives = 158/295 (53%), Gaps = 14/295 (4%)
Query: 25 LNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHENLICL 84
LN + G +G+V A D T + VA+K++ + RE+ + +H N++ +
Sbjct: 43 LNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTV 102
Query: 85 EDIFL-SPLEDIYFVTELQGTDLHRLLQT--RPLEKQFVQYFLYQILRGLKYVHSAGVIH 141
+I + S ++ IY V DL L++T +P V+ + Q+LRG+K++H ++H
Sbjct: 103 REIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILH 162
Query: 142 RDLKPSNILINENCDLKICDFGLARIQDPQMTGY---VSTRYYRAPEIMLTWQKYNVEVD 198
RDLK SN+L++ LK+ DFGLAR + Y V T++YRAPE++L ++Y+ VD
Sbjct: 163 RDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVD 222
Query: 199 IWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLKFVTSLPHR 258
+WS GCIF E++ KPLFPG + Q + + LG+P + + +K +T H
Sbjct: 223 MWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSEH- 281
Query: 259 DPVPFSS---RFQNLEPD-AIDLLEKMLVFDPKKRITAADALAHPYLSPYHDPTD 309
P+++ RF L D DL+ K L + P +RI+A D L H Y P D
Sbjct: 282 ---PYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPID 333
>Hs11995474 [G] KOG0658 Glycogen synthase kinase-3
Length = 483
Score = 159 bits (401), Expect = 1e-38
Identities = 99/293 (33%), Positives = 159/293 (53%), Gaps = 23/293 (7%)
Query: 22 YTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHENL 81
YT++ +G G+FG+V A T + VAIKK+++ + REL++++ L H N+
Sbjct: 119 YTDIKVIGNGSFGVVYQARLAETRELVAIKKVLQD------KRFKNRELQIMRKLDHCNI 172
Query: 82 ICLEDIFLSPLE---DIYF--VTELQGTDLHRLLQTRPLEKQ-----FVQYFLYQILRGL 131
+ L F S E ++Y V E ++R+ + K +V+ ++YQ+ R L
Sbjct: 173 VRLRYFFYSSGEKKDELYLNLVLEYVPETVYRVARHFTKAKLTIPILYVKVYMYQLFRSL 232
Query: 132 KYVHSAGVIHRDLKPSNILIN-ENCDLKICDFGLAR--IQDPQMTGYVSTRYYRAPEIML 188
Y+HS GV HRD+KP N+L++ + LK+CDFG A+ ++ Y+ +RYYRAPE++
Sbjct: 233 AYIHSQGVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIF 292
Query: 189 TWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENT 248
Y +D+WSAGC+ AE++ G+P+FPG V Q I +LG+P ++ I + T
Sbjct: 293 GATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYT 352
Query: 249 -LKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPY 300
KF H F SR P+AI L +L + P R++ +A AH +
Sbjct: 353 EFKFPQIKAHPWTKVFKSR---TPPEAIALCSSLLEYTPSSRLSPLEACAHSF 402
>At1g76540 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 313
Score = 159 bits (401), Expect = 1e-38
Identities = 98/293 (33%), Positives = 157/293 (53%), Gaps = 17/293 (5%)
Query: 22 YTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHL-RHEN 80
+ L VG G +G V A + T + VA+KK + T RE+ +L+ L R +
Sbjct: 14 FEKLEKVGEGTYGKVYRAREKATGKIVALKKTRLHEDEEGVPSTTLREISILRMLARDPH 73
Query: 81 LICLEDIFLSPLED----IYFVTELQGTDLHRLLQT-----RPLEKQFVQYFLYQILRGL 131
++ L D+ ++ +Y V E TD+ + +++ + + Q ++ +YQ+ +G+
Sbjct: 74 VVRLMDVKQGLSKEGKTVLYLVFEYMDTDVKKFIRSFRSTGKNIPTQTIKSLMYQLCKGM 133
Query: 132 KYVHSAGVIHRDLKPSNILIN-ENCDLKICDFGLARIQDPQMTGY---VSTRYYRAPEIM 187
+ H G++HRDLKP N+L++ + LKI D GLAR M Y + T +YRAPE++
Sbjct: 134 AFCHGHGILHRDLKPHNLLMDPKTMRLKIADLGLARAFTLPMKKYTHEILTLWYRAPEVL 193
Query: 188 LTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSEN 247
L Y+ VD+WS GCIFAE++ + +F G + Q I L G+P +++ + +
Sbjct: 194 LGATHYSTAVDMWSVGCIFAELVTNQAIFQGDSELQQLLHIFKLFGTPNEEMWPGV---S 250
Query: 248 TLKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPY 300
TLK P P SS NL+ +DLL KML ++P KRI+A A+ HPY
Sbjct: 251 TLKNWHEYPQWKPSTLSSAVPNLDEAGVDLLSKMLQYEPAKRISAKMAMEHPY 303
>At1g57700 [D] KOG0600 Cdc2-related protein kinase
Length = 686
Score = 159 bits (401), Expect = 1e-38
Identities = 107/308 (34%), Positives = 160/308 (51%), Gaps = 19/308 (6%)
Query: 11 IFGTVFEITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKI----MKPFSTSVLAKRT 66
I G + + + L +G G + V A D T+Q VA+KK+ M P S +A
Sbjct: 135 INGWIPRSADSFEKLEMIGQGTYSSVYRARDLETNQIVALKKVRFANMDPESVRFMA--- 191
Query: 67 YRELKLLKHLRHENLICLEDIFLSPLE-DIYFVTELQGTDLHRLLQTRPLEKQFVQYFLY 125
RE+ +L+ L H N++ LE + +S +Y + E DL L T ++ Q
Sbjct: 192 -REIIILRRLNHPNVMKLEGLIISKASGSMYLIFEYMDHDLAGLASTPGIKFSQAQ---- 246
Query: 126 QILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQ----MTGYVSTRYY 181
Q+L GL++ HS GV+HRD+K SN+L++ N +LKI DFGL+ Q +T V T +Y
Sbjct: 247 QLLLGLEHCHSCGVLHRDIKCSNLLLDRNNNLKIGDFGLSNFYRGQRKQPLTSRVVTLWY 306
Query: 182 RAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVID 241
R PE++L Y V VD+WS GCI AE+ GKPL PG+ V Q I L GSP ++
Sbjct: 307 RPPELLLGSTDYGVTVDLWSTGCILAELFTGKPLLPGRTEVEQMHKIFKLCGSPSEEYWR 366
Query: 242 TICSENTLKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPYL 301
+ F P++ V + F++L A+ LLE +L +P R TA+ AL +
Sbjct: 367 RSRLRHATIFKPQHPYKRCV--ADTFKDLPSSALALLEVLLAVEPDARGTASSALQSEFF 424
Query: 302 SPYHDPTD 309
+ P++
Sbjct: 425 TTKPFPSE 432
>At5g39420 [D] KOG0600 Cdc2-related protein kinase
Length = 576
Score = 158 bits (400), Expect = 1e-38
Identities = 111/324 (34%), Positives = 164/324 (50%), Gaps = 23/324 (7%)
Query: 22 YTNLNPVGMGAFGLVCSATDTLTSQPVAIKKI----MKPFSTSVLAKRTYRELKLLKHLR 77
+ L +G G + V A + T + VA+KK+ ++P S +A RE+ +L+ L
Sbjct: 105 FQKLEKIGQGTYSSVFRAREVETGKMVALKKVKFDNLQPESIRFMA----REILILRKLN 160
Query: 78 HENLICLEDIFLSPLED-IYFVTELQGTDLHRLLQTRPLE--KQFVQYFLYQILRGLKYV 134
H N++ LE I S IY V E DL L + + ++ ++ Q+L GL++
Sbjct: 161 HPNIMKLEGIVTSRASSSIYLVFEYMEHDLAGLSSNPDIRFTEPQIKCYMKQLLWGLEHC 220
Query: 135 HSAGVIHRDLKPSNILINENCDLKICDFGLARIQDP----QMTGYVSTRYYRAPEIMLTW 190
H GVIHRD+K SNIL+N LK+ DFGLA + P Q+T V T +YRAPE+++
Sbjct: 221 HMRGVIHRDIKASNILVNNKGVLKLGDFGLANVVTPSNKNQLTSRVVTLWYRAPELLMGS 280
Query: 191 QKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLK 250
Y V VD+WS GC+FAE++ GKP+ G+ + Q I L GSP D+ L
Sbjct: 281 TSYGVSVDLWSVGCVFAEILMGKPILKGRTEIEQLHKIYKLCGSPQ----DSFWKRTKLP 336
Query: 251 FVTSL--PHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADAL-AHPYLSPYHDP 307
TS H R ++L + LLE +L +P KR TA+ AL + L + P
Sbjct: 337 HATSFKPQHTYEATLRERCKDLSATGVYLLETLLSMEPDKRGTASSALNSEDTLEVKNIP 396
Query: 308 TDEPIAEAKFDWN-FNDADLPVDT 330
+ A N + +DLP+ T
Sbjct: 397 NEASRATTTTHGNYYKVSDLPMTT 420
>Hs16357494 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 775
Score = 158 bits (399), Expect = 2e-38
Identities = 98/295 (33%), Positives = 157/295 (53%), Gaps = 14/295 (4%)
Query: 25 LNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHENLICL 84
LN + G +G+V A D T + VA+K++ + RE+ + +H N++ +
Sbjct: 421 LNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKENEGFPITSLREINTILKAQHPNIVTV 480
Query: 85 EDIFL-SPLEDIYFVTELQGTDLHRLLQT--RPLEKQFVQYFLYQILRGLKYVHSAGVIH 141
+I + S ++ IY V DL L++T +P V+ + Q+LRG+K++H ++H
Sbjct: 481 REIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILH 540
Query: 142 RDLKPSNILINENCDLKICDFGLARIQDPQMTGY---VSTRYYRAPEIMLTWQKYNVEVD 198
RDLK SN+L++ LK+ DFGLAR + Y V T++YRAPE++L ++Y+ VD
Sbjct: 541 RDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVD 600
Query: 199 IWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLKFVTSLPHR 258
+WS GCIF E++ KPLFPG + Q + + LG+P + + +K +T H
Sbjct: 601 MWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSEH- 659
Query: 259 DPVPFSS---RF-QNLEPDAIDLLEKMLVFDPKKRITAADALAHPYLSPYHDPTD 309
P+++ RF L DL+ K L + P +RI+A D L H Y P D
Sbjct: 660 ---PYNNLRKRFGALLSEQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPID 711
>Hs16357492 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 777
Score = 158 bits (399), Expect = 2e-38
Identities = 98/295 (33%), Positives = 157/295 (53%), Gaps = 14/295 (4%)
Query: 25 LNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHENLICL 84
LN + G +G+V A D T + VA+K++ + RE+ + +H N++ +
Sbjct: 423 LNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKENEGFPITSLREINTILKAQHPNIVTV 482
Query: 85 EDIFL-SPLEDIYFVTELQGTDLHRLLQT--RPLEKQFVQYFLYQILRGLKYVHSAGVIH 141
+I + S ++ IY V DL L++T +P V+ + Q+LRG+K++H ++H
Sbjct: 483 REIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILH 542
Query: 142 RDLKPSNILINENCDLKICDFGLARIQDPQMTGY---VSTRYYRAPEIMLTWQKYNVEVD 198
RDLK SN+L++ LK+ DFGLAR + Y V T++YRAPE++L ++Y+ VD
Sbjct: 543 RDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVD 602
Query: 199 IWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLKFVTSLPHR 258
+WS GCIF E++ KPLFPG + Q + + LG+P + + +K +T H
Sbjct: 603 MWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSEH- 661
Query: 259 DPVPFSS---RF-QNLEPDAIDLLEKMLVFDPKKRITAADALAHPYLSPYHDPTD 309
P+++ RF L DL+ K L + P +RI+A D L H Y P D
Sbjct: 662 ---PYNNLRKRFGALLSEQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPID 713
>At1g74330 [D] KOG0600 Cdc2-related protein kinase
Length = 445
Score = 158 bits (399), Expect = 2e-38
Identities = 108/318 (33%), Positives = 165/318 (50%), Gaps = 22/318 (6%)
Query: 11 IFGTVFEITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKI----MKPFSTSVLAKRT 66
I G V ++ + L +G G + V A +T T + VA+KK+ +P S +A
Sbjct: 110 IHGWVPLRSDAFEKLEKIGQGTYSNVFRAVETETGRIVALKKVRFDNFEPESVKFMA--- 166
Query: 67 YRELKLLKHLRHENLICLEDIFLSPLE-DIYFVTELQGTDLHRLLQTRPLE--KQFVQYF 123
RE+ +L+ L H N+I LE + S L +I V E DL LL + ++ ++ +
Sbjct: 167 -REILILRRLNHPNIIKLEGLITSKLSCNIQLVFEYMEHDLTGLLSSPDIKFTTPQIKCY 225
Query: 124 LYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQ------MTGYVS 177
+ Q+L GL + HS GV+HRD+K SN+L++ LK+ DFGLA + +T V
Sbjct: 226 MKQLLSGLDHCHSRGVMHRDIKGSNLLLSNEGILKVADFGLANFSNSSGHKKKPLTSRVV 285
Query: 178 TRYYRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPK 237
T +YR PE++L Y VD+WS GC+FAE++ GKP+ G+ V Q I L GSPP+
Sbjct: 286 TLWYRPPELLLGATDYGASVDLWSVGCVFAELLLGKPILRGRTEVEQLHKIFKLCGSPPE 345
Query: 238 DVIDTICSENTLKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALA 297
D + + F + + ++L I+L+E +L DP KR TA+ AL
Sbjct: 346 DYWKKSKLPHAMLFKPQQTYDSCL--RETLKDLSETEINLIETLLSIDPHKRGTASSALV 403
Query: 298 HPYLS--PYH-DPTDEPI 312
Y + P+ DP+ PI
Sbjct: 404 SQYFTTKPFACDPSSLPI 421
>At1g20930 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 315
Score = 158 bits (399), Expect = 2e-38
Identities = 101/299 (33%), Positives = 158/299 (52%), Gaps = 17/299 (5%)
Query: 22 YTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHL-RHEN 80
+ L VG G +G V A + T VA+KK + T RE+ +L+ L R +
Sbjct: 16 FEKLEKVGEGTYGKVYRAREKATGMIVALKKTRLHEDEEGVPPTTLREISILRMLARDPH 75
Query: 81 LICLEDIFLSPLED----IYFVTELQGTDLHRLLQT-----RPLEKQFVQYFLYQILRGL 131
++ L D+ ++ +Y V E TDL + +++ + + + V+ +YQ+ +G+
Sbjct: 76 IVRLMDVKQGINKEGKTVLYLVFEYVDTDLKKFIRSFRQAGQNIPQNTVKCLMYQLCKGM 135
Query: 132 KYVHSAGVIHRDLKPSNILIN-ENCDLKICDFGLARIQDPQMTGY---VSTRYYRAPEIM 187
+ H GV+HRDLKP N+L++ + LKI D GLAR M Y + T +YRAPE++
Sbjct: 136 AFCHGHGVLHRDLKPHNLLMDRKTMTLKIADLGLARAFTLPMKKYTHEILTLWYRAPEVL 195
Query: 188 LTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSEN 247
L Y+ VD+WS GCIFAE++ + +F G + Q I LLG+P ++V + +
Sbjct: 196 LGATHYSTGVDMWSVGCIFAELVTKQAIFAGDSELQQLLRIFRLLGTPNEEVWPGV---S 252
Query: 248 TLKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPYLSPYHD 306
LK P P+ S+ NL+ +DLL KML ++P KRI+A A+ HPY D
Sbjct: 253 KLKDWHEYPQWKPLSLSTAVPNLDEAGLDLLSKMLEYEPAKRISAKKAMEHPYFDDLPD 311
>Hs6912584 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 451
Score = 157 bits (397), Expect = 3e-38
Identities = 110/305 (36%), Positives = 158/305 (51%), Gaps = 31/305 (10%)
Query: 16 FEITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIK--KIMKPFSTSVLAKRTYRELKLL 73
F + Y L +G G++ V + + VA+K ++ + T A RE LL
Sbjct: 111 FGKADSYEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPFTA---IREASLL 167
Query: 74 KHLRHENLICLEDIFLSPLEDIYFVTELQGTDLHRLLQTRP--LEKQFVQYFLYQILRGL 131
K L+H N++ L DI + E + V E TDL + + P L V+ FL+Q+LRGL
Sbjct: 168 KGLKHANIVLLHDI-IHTKETLTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQLLRGL 226
Query: 132 KYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQMTGY---VSTRYYRAPEIML 188
Y+H ++HRDLKP N+LI++ +LK+ DFGLAR + Y V T +YR P+++L
Sbjct: 227 SYIHQRYILHRDLKPQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLL 286
Query: 189 TWQKYNVEVDIWSAGCIFAEMIEGKPLFPG-KDHVHQFSIITDLLGSPPKDVIDTICSEN 247
+Y+ +D+W GCIF EMI+G FPG KD Q I +LG+P +E+
Sbjct: 287 GSTEYSTCLDMWGVGCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTP---------NED 337
Query: 248 TLKFVTSLPHRDPVPFS-SRFQNLEP---------DAIDLLEKMLVFDPKKRITAADALA 297
T V SLPH P F+ +NL A DL K+L PK R++A AL+
Sbjct: 338 TWPGVHSLPHFKPERFTLYSSKNLRQAWNKLSYVNHAEDLASKLLQCSPKNRLSAQAALS 397
Query: 298 HPYLS 302
H Y S
Sbjct: 398 HEYFS 402
>CE23605 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 384
Score = 157 bits (397), Expect = 3e-38
Identities = 108/315 (34%), Positives = 162/315 (51%), Gaps = 28/315 (8%)
Query: 13 GTVFEITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLA--KRTYREL 70
GT F + RY N+ P V A D + +PV IKK+M P S +R REL
Sbjct: 12 GTFFTVPVRYVNVQPFQFDK-PFVVHAFDQVLGRPVVIKKVMLPDSLHDRQPWRRAQREL 70
Query: 71 KLLKHLRHENLICLEDIFL---SPLE--DIYFVTELQGTDLHRLLQTRPLE--KQFVQYF 123
+ ++ +N++ + F +PL+ + Y V E + L + E + V+
Sbjct: 71 NCMLNIEDDNVVKMYSTFTPAENPLKMTEFYIVREYMHGTMKNLSASTFNEGGHRTVKSI 130
Query: 124 LYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDP-QMTGYVSTRYYR 182
+ I RG++Y+H+ + HRDLKP NIL+N+ D+K+CDFG + +DP T Y+ R+YR
Sbjct: 131 FFDICRGVQYLHAMRISHRDLKPENILMNQEGDVKLCDFGHSNKEDPTSNTPYIVQRFYR 190
Query: 183 APEIML-TWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVID 241
APEI+ T VDIWS GCI AE++ G LF GKDH+ QF ++ LG+
Sbjct: 191 APEIICETTDNNKTNVDIWSLGCILAELLTGHVLFRGKDHIDQFILMVQFLGNAGPSFYS 250
Query: 242 TICSENTLKFVTSL---PHRDPVPFSSRFQN--------LEPD----AIDLLEKMLVFDP 286
+ +E+ F+ ++ P+ F SRF + EP + DLL +MLV +P
Sbjct: 251 QM-NEHARNFLLRYNLDQYQAPINFYSRFPDTVFQGVLQFEPKECDMSRDLLFRMLVINP 309
Query: 287 KKRITAADALAHPYL 301
R+ L+HPYL
Sbjct: 310 DDRLNIQMVLSHPYL 324
>CE11556 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 305
Score = 157 bits (396), Expect = 4e-38
Identities = 94/224 (41%), Positives = 129/224 (56%), Gaps = 27/224 (12%)
Query: 21 RYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHEN 80
RY + G GAFGLV A DTLTS+ VAIK+IM P + V R E+ L++L H N
Sbjct: 7 RYETIQVAGRGAFGLVVIARDTLTSKRVAIKRIMVPNVSKVSLAR---EISCLRNLHHRN 63
Query: 81 LICLEDIFLSPLEDIY-FVTELQGTDLHRLLQTRPLEKQFVQYFLYQILRGLKYVHSAGV 139
++ L D F P D+ VTE E + Y+ QIL G+ Y+HS +
Sbjct: 64 ILKLLDCF--PSADLMSIVTE---------------EVPYTWYYT-QILSGIAYLHSKEI 105
Query: 140 IHRDLKPSNILINENCDLKICDFGLARIQDPQMTGY-----VSTRYYRAPEIMLTWQKYN 194
+HRD+KP NIL+ +KI DFG A P+ V+TR+YRAPE++ +KY
Sbjct: 106 MHRDIKPENILVTSRNVVKIADFGQACFYMPKDPNQEYDVNVATRWYRAPELLFGSKKYK 165
Query: 195 VEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKD 238
+VDIW+ GCI AE++ GKP+FPG+ + Q SII +LG+P +D
Sbjct: 166 PDVDIWAIGCILAELVRGKPIFPGRSELEQISIIFGVLGTPNED 209
>Hs4502741 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 326
Score = 156 bits (394), Expect = 7e-38
Identities = 109/303 (35%), Positives = 154/303 (49%), Gaps = 38/303 (12%)
Query: 21 RYTNLNPVGMGAFGLVCSATDTLTS-QPVAIKKIMKPFSTSVLAKRTYRELKLLKHLR-- 77
+Y + +G GA+G V A D + VA+K++ + T RE+ +L+HL
Sbjct: 12 QYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLRHLETF 71
Query: 78 -HENLICLEDIFLSPLED----IYFVTELQGTDLHRLLQTRP---LEKQFVQYFLYQILR 129
H N++ L D+ D + V E DL L P + + ++ ++Q+LR
Sbjct: 72 EHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQLLR 131
Query: 130 GLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQM--TGYVSTRYYRAPEIM 187
GL ++HS V+HRDLKP NIL+ + +K+ DFGLARI QM T V T +YRAPE++
Sbjct: 132 GLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMALTSVVVTLWYRAPEVL 191
Query: 188 LTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSP-----PKDVIDT 242
L Y VD+WS GCIFAEM KPLF G V Q I D++G P P+DV
Sbjct: 192 LQ-SSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGEEDWPRDV--- 247
Query: 243 ICSENTLKFVTSLPH-----RDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALA 297
+LP + P +++ DLL K L F+P KRI+A AL+
Sbjct: 248 -----------ALPRQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALS 296
Query: 298 HPY 300
HPY
Sbjct: 297 HPY 299
>ECU11g1290 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 328
Score = 155 bits (393), Expect = 9e-38
Identities = 95/294 (32%), Positives = 156/294 (52%), Gaps = 24/294 (8%)
Query: 22 YTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKP---FSTSVLAKRTYRELKLLKHLRH 78
Y + + G+FG V ++ A+K+ M P + T+ + RE+ +LKH+RH
Sbjct: 26 YEKVCRISSGSFGNVYRVRRKTDNRVFALKR-MNPSMCYDTNGFSILYIREVMILKHIRH 84
Query: 79 ENLICLEDIFLS-PLEDIYFVTELQGTDLHRLLQT-RPLEKQFVQYFLYQILRGLKYVHS 136
N++ +E++ + D + V E TDL ++ + + + ++ Q+L+GLK++H
Sbjct: 85 RNIMEIEEVVEGCEINDFFIVMECCDTDLRSVIHSVGKIGMKAARFLTCQMLKGLKFLHG 144
Query: 137 AGVIHRDLKPSNILINENCDLKICDFGLARIQDPQMTGYVSTRYYRAPEIMLTWQKYNVE 196
AG++HRDLKPSNIL+ + L+I DFGLAR + QMT V T +YR EI+L + Y+
Sbjct: 145 AGIVHRDLKPSNILLMRDGGLRIADFGLARAIESQMTNLVVTLWYRPIEILLGSETYDES 204
Query: 197 VDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLKFVTSLP 256
+D+WS GC+ EM+ G+P+ G+ + Q I LLG P + + LP
Sbjct: 205 IDMWSVGCVVGEMLRGEPILAGEGEMDQLDRIFRLLGYPTDADFEGL----------DLP 254
Query: 257 H----RDPVPFSSRFQN----LEPDAIDLLEKMLVFDPKKRITAADALAHPYLS 302
H R P F + F+ +A + +L FDP+KR TA+ L +++
Sbjct: 255 HFKNIRRPSTFEASFEGDFECYGEEAASFVRNLLSFDPRKRCTASQGLCSGFVA 308
>Hs21361340 [G] KOG0658 Glycogen synthase kinase-3
Length = 433
Score = 155 bits (392), Expect = 1e-37
Identities = 98/310 (31%), Positives = 164/310 (52%), Gaps = 30/310 (9%)
Query: 22 YTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHENL 81
YT+ +G G+FG+V A + + VAIKK+++ + REL++++ L H N+
Sbjct: 56 YTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQD------KRFKNRELQIMRKLDHCNI 109
Query: 82 ICLEDIFLSPLE---DIYF--VTELQGTDLHRLLQTRPLEKQ-----FVQYFLYQILRGL 131
+ L F S E ++Y V + ++R+ + KQ +V+ ++YQ+ R L
Sbjct: 110 VRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSL 169
Query: 132 KYVHSAGVIHRDLKPSNILIN-ENCDLKICDFGLAR--IQDPQMTGYVSTRYYRAPEIML 188
Y+HS G+ HRD+KP N+L++ + LK+CDFG A+ ++ Y+ +RYYRAPE++
Sbjct: 170 AYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIF 229
Query: 189 TWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENT 248
Y +D+WSAGC+ AE++ G+P+FPG V Q I +LG+P ++ I + T
Sbjct: 230 GATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYT 289
Query: 249 -LKF--VTSLPHRDPVPFSSRFQN--------LEPDAIDLLEKMLVFDPKKRITAADALA 297
KF + + P + F + P+AI L ++L + P R+T +A A
Sbjct: 290 EFKFPQIKAHPWTKDSSGTGHFTSGVRVFRPRTPPEAIALCSRLLEYTPTARLTPLEACA 349
Query: 298 HPYLSPYHDP 307
H + DP
Sbjct: 350 HSFFDELRDP 359
>SPCC16C4.11 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 288
Score = 154 bits (390), Expect = 2e-37
Identities = 99/293 (33%), Positives = 148/293 (49%), Gaps = 25/293 (8%)
Query: 22 YTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHENL 81
Y L +G G + V + +T + VA+K +++ + RE+ L+K LRH N+
Sbjct: 3 YQRLEKLGEGTYAHVYKGQNRVTGEIVALK-VIRIDADEGTPSTAIREISLMKELRHPNI 61
Query: 82 ICLEDIFLSPLEDIYFVTELQGTDLHRLLQTR----PLEKQFVQYFLYQILRGLKYVHSA 137
+ L D+ L + V E DL + + T L V+ F Q+L+G+ + H
Sbjct: 62 MSLSDV-LQTENKLMLVFEYMEKDLKKYMDTYGNQGALPPSQVKNFTQQLLKGISFCHEN 120
Query: 138 GVIHRDLKPSNILINENCDLKICDFGLAR---IQDPQMTGYVSTRYYRAPEIMLTWQKYN 194
V+HRDLKP N+LIN +LK+ DFGLAR I + V T +YRAP+++L + Y+
Sbjct: 121 RVLHRDLKPQNLLINSRGELKLADFGLARSIGIPVNTFSNEVVTLWYRAPDVLLGSRVYS 180
Query: 195 VEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLKFVTS 254
+DIWS GCI AEM G+PLF G ++ Q I LLG+P +E + ++
Sbjct: 181 TSIDIWSVGCIMAEMATGRPLFAGSNNEDQLLKIFRLLGTP---------TEQSWPGISL 231
Query: 255 LPHRDPV-------PFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPY 300
LP P + F +P +DLL +ML P+ R T DAL H +
Sbjct: 232 LPEYKPTFPIYKAQDLAYLFPTFDPLGLDLLRRMLRLQPELRTTGQDALQHAW 284
>CE18009 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 384
Score = 154 bits (390), Expect = 2e-37
Identities = 99/315 (31%), Positives = 157/315 (49%), Gaps = 40/315 (12%)
Query: 17 EITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHL 76
++ R+ +L +G G +G+V A + A+K I + RE+ +K L
Sbjct: 40 DLQGRFCSLRRIGEGTYGVVFKAIHVRDNVKCALKMIRTDRDEEGIPSTCLREISCIKDL 99
Query: 77 RHENLICLEDIF---------------LSPLEDIYFVTELQGTDLHRLLQ-----TRPLE 116
+H+N++ L DI S +Y V E DL LL+ L
Sbjct: 100 QHDNIVTLFDIIYASHFLNYNNIFFEKFSSNSKLYMVFEFIDRDLKNLLEMLEPTNSVLP 159
Query: 117 KQFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLAR---IQDPQMT 173
+V+ F++Q+L L Y H ++HRDLKP NIL++++ +KI DFGLAR T
Sbjct: 160 PNYVKSFMWQLLSALSYCHLRRIVHRDLKPQNILVSDSGVIKIADFGLARNFSFPSRNYT 219
Query: 174 GYVSTRYYRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLG 233
V T +YR PEI+L Q+Y+ +D+WS GCIF+E+ KPLFPG+ + Q I +++G
Sbjct: 220 HEVVTLWYRPPEILLGSQRYSTSLDMWSLGCIFSEIASNKPLFPGECEISQLFKIFEIVG 279
Query: 234 SPPKDVIDTICSENTLKFVTSLPHRDPV--PFSSRFQNLEP------DAIDLLEKMLVFD 285
+P + + V S PH V + + LE + +D+L ++L +
Sbjct: 280 TP---------NIKSWPGVDSFPHYKAVFPQWPVNLKKLEETSCLTGNGLDVLREILRYP 330
Query: 286 PKKRITAADALAHPY 300
P++R+TA AL+H Y
Sbjct: 331 PERRLTAKGALSHRY 345
>YPR161c [D] KOG0600 Cdc2-related protein kinase
Length = 657
Score = 154 bits (388), Expect = 3e-37
Identities = 104/331 (31%), Positives = 158/331 (47%), Gaps = 34/331 (10%)
Query: 10 QIFG-TVFEITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYR 68
+++G TVF+ N Y +G G FG V T + VA+KKI+ + R
Sbjct: 49 KVYGCTVFQ--NHYREDEKLGQGTFGEVYKGIHLETQRQVAMKKIIVSVEKDLFPITAQR 106
Query: 69 ELKLLKHLRHENLICLEDIFLSPLEDI------------YFVTELQGTDLHRLLQTRPLE 116
E+ +LK L H+N+I L ++ DI Y + DL +L +
Sbjct: 107 EITILKRLNHKNIIKLIEMVYDHSPDITNAASSNLHKSFYMILPYMVADLSGVLHNPRIN 166
Query: 117 KQF--VQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARI------- 167
+ ++ + QIL GL Y+H A +HRD+K +NILI+ N LK+ DFGLAR+
Sbjct: 167 LEMCDIKNMMLQILEGLNYIHCAKFMHRDIKTANILIDHNGVLKLADFGLARLYYGCPPN 226
Query: 168 --------QDPQMTGYVSTRYYRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGK 219
+ T V TR+YRAPE++L ++Y VDIW GC+FAE E KP+ GK
Sbjct: 227 LKYPGGAGSGAKYTSVVVTRWYRAPELVLGDKQYTTAVDIWGVGCVFAEFFEKKPILQGK 286
Query: 220 DHVHQFSIITDLLGSPPKDVIDTICSENTLKFVTSLPHRDPVPFSSRFQNLEPDAIDLLE 279
+ Q +I LLG+P ++ D + + + P + L +D L
Sbjct: 287 TDIDQGHVIFKLLGTPTEE--DWAVARYLPGAELTTTNYKPTLRERFGKYLSETGLDFLG 344
Query: 280 KMLVFDPKKRITAADALAHPYLSPYHDPTDE 310
++L DP KR+TA A HP+ P+++
Sbjct: 345 QLLALDPYKRLTAMSAKHHPWFKEDPLPSEK 375
>SPAC3C7.06c [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 650
Score = 153 bits (386), Expect = 6e-37
Identities = 108/294 (36%), Positives = 157/294 (52%), Gaps = 25/294 (8%)
Query: 22 YTNLNPVGMGAFGLVCSATD-TLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHEN 80
Y + VG G FG V AT T + + VAIK + K + A R LL+ +EN
Sbjct: 36 YNVVRKVGDGTFGSVYLATTKTPSKEVVAIKSMKKKLAKVSDATRLREVHSLLRLSENEN 95
Query: 81 LICLEDIFLSPLEDIYFVTELQGTDLHRLLQTR---PLEKQFVQYFLYQILRGLKYVHSA 137
++ + D+++ ++ V E +L++L+ TR PL + VQ + QI +GL ++H+
Sbjct: 96 IVNIFDLYIDQFRCLHIVMEFLDCNLYQLISTRKNDPLTLEQVQDIMRQIFKGLNHIHTN 155
Query: 138 GVIHRDLKPSNILINENCD-----LKICDFGLARIQD--PQMTGYVSTRYYRAPEIMLTW 190
G HRD+KP NILI+ N D +KI DFGLAR + P T YVSTR+YRAPE++L
Sbjct: 156 GFFHRDMKPENILISSNSDSSSFNVKIADFGLAREINSRPPYTEYVSTRWYRAPELLLRD 215
Query: 191 QKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDT------IC 244
Y+ VDI++AGC+ E+ +P+FPG D Q + ++LGSP + +T I
Sbjct: 216 SYYSFPVDIYAAGCMAFEIATLQPIFPGNDDFDQLYKMCEILGSPDEQSQNTGDKGGGIW 275
Query: 245 SENTL---KFVTSLPHRDPVPFSSRFQ---NLEPDAIDLLEKMLVFDPKKRITA 292
L K SLP P+ F F NL +L ++L +DP KR TA
Sbjct: 276 DRAELLANKLGISLPKMAPLDFGDLFSPPWNLA--FASMLSQLLKWDPAKRPTA 327
>7296451 [D] KOG0600 Cdc2-related protein kinase
Length = 1157
Score = 152 bits (384), Expect = 1e-36
Identities = 102/305 (33%), Positives = 151/305 (49%), Gaps = 26/305 (8%)
Query: 28 VGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHENLICLEDI 87
+G G +G V A D T+ VA+KK+ RE+K+L+ L H N++ L +I
Sbjct: 810 IGEGTYGQVYKARDHHTNDMVALKKVRLEHEKEGFPITAVREIKILRQLNHRNIVNLHEI 869
Query: 88 ---------FLSPLEDIYFVTELQGTDLHRLLQTRPLE--KQFVQYFLYQILRGLKYVHS 136
F Y V E DL LL++ ++ ++ + Q+L GL Y H
Sbjct: 870 VTDKQDAVEFRKDKGSFYLVFEYMDHDLMGLLESGMVDFNEENNASIMKQLLDGLNYCHK 929
Query: 137 AGVIHRDLKPSNILINENCDLKICDFGLARI-----QDPQMTGYVSTRYYRAPEIMLTWQ 191
+HRD+K SNIL+N +K+ DFGLAR+ ++ T V T +YR PE++L +
Sbjct: 930 KNFLHRDIKCSNILMNNRGKVKLADFGLARLYNADDRERPYTNKVITLWYRPPELLLGEE 989
Query: 192 KYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICS---ENT 248
+Y +D+WS GCI E+ +PLF + Q I+ + GSP V + +T
Sbjct: 990 RYGPSIDVWSCGCILGELFVKRPLFQANAEMAQLETISKICGSPVPAVWPNVIKLPLFHT 1049
Query: 249 LKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPYL---SPYH 305
LK + R F+ + A+DLL+KML DP KRITA DAL P+L +P
Sbjct: 1050 LKQKKTHRRR----LREDFEFMPAPALDLLDKMLDLDPDKRITAEDALRSPWLRKINPDE 1105
Query: 306 DPTDE 310
PT +
Sbjct: 1106 MPTPQ 1110
>SPBPI064 [G] KOG0658 Glycogen synthase kinase-3
Length = 350
Score = 152 bits (383), Expect = 1e-36
Identities = 98/287 (34%), Positives = 151/287 (52%), Gaps = 26/287 (9%)
Query: 65 RTYRELKLLKHLRHENLICLEDIFLS--PLED-------IYFVTELQGTDLHRLLQTRP- 114
R REL++++ + H N+I L F + P +D + ++ E D+ + R
Sbjct: 31 RVNRELQIMRAISHPNIIKLIAFFHTHNPSKDETHLCLLLEYMPETVFDDMRWYTRRRKS 90
Query: 115 LEKQFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCD-LKICDFGLARIQDPQM- 172
+ ++ + +Q+ R L Y+HS GV HRD+KP N+L++ LK+CDFG A++ P
Sbjct: 91 IPNLSIKLYAFQLFRALAYLHSTGVCHRDIKPQNLLVDYKTGILKLCDFGSAKVLVPSEP 150
Query: 173 -TGYVSTRYYRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDL 231
Y+ +RYYRAPE++ Y ++D+WSA C+ AE+ G+PLFPG V Q I +
Sbjct: 151 NVSYICSRYYRAPELVFGATHYTTKIDVWSAACVIAELFIGRPLFPGDSSVEQLVEIIRV 210
Query: 232 LGSPPKDVIDTICSENTLKFVTSLPHRDPVPFSSRF-QNLEPDAIDLLEKMLVFDPKKRI 290
LG+P I ++ + N + SLP+ P S N +A+DLL KML + P KRI
Sbjct: 211 LGTPSYHEI-SVMNPNYVNH--SLPNVRPHTLESVMPHNCTKNAMDLLHKMLTYVPSKRI 267
Query: 291 TAADALAHPYLSPYHDPT-------DEPIAEAKFD--WNFNDADLPV 328
+A + L HP+ DP DE E +NFN A+L +
Sbjct: 268 SAIEVLTHPFFDELRDPNCMYHCSRDEGTIERHLPPLFNFNLAELSI 314
>YDL079c [G] KOG0658 Glycogen synthase kinase-3
Length = 501
Score = 151 bits (382), Expect = 2e-36
Identities = 101/302 (33%), Positives = 156/302 (51%), Gaps = 30/302 (9%)
Query: 22 YTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTY--RELKLLKHLRHE 79
Y VG G+FG+V + T+Q VAIKK VL R Y REL+ +K L H
Sbjct: 164 YPTTEVVGHGSFGVVVTTVIIETNQKVAIKK--------VLQDRRYKNRELETMKMLCHP 215
Query: 80 NLICLEDIFLSPLED----IYFVTELQGTDLHRLLQ-----TRPLEKQFVQYFLYQILRG 130
N + L+ F E+ + V + L++ L+ + + ++++ YQ+ +
Sbjct: 216 NTVGLQYYFYEKDEEDEVYLNLVLDYMPQSLYQRLRHFVNLKMQMPRVEIKFYAYQLFKA 275
Query: 131 LKYVHSAG-VIHRDLKPSNILINENC-DLKICDFGLARIQDPQM--TGYVSTRYYRAPEI 186
L Y+H+ + HRD+KP N+L++ KICDFG A+ P Y+ +RYYRAPE+
Sbjct: 276 LNYLHNVPRICHRDIKPQNLLVDPTTFSFKICDFGSAKCLKPDQPNVSYICSRYYRAPEL 335
Query: 187 MLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSE 246
M Y+ +VD+WS+ C+ AE++ GKPLF G+ + Q I ++G P KD I + +
Sbjct: 336 MFGATNYSNQVDVWSSACVIAELLLGKPLFSGESGIDQLVEIIKIMGIPTKDEISGM-NP 394
Query: 247 NTLKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPYLSPYHD 306
N V P+ P+ + F+ +PD +DLL K L + P +R+ L LS Y D
Sbjct: 395 NYEDHV--FPNIKPITLAEIFKAEDPDTLDLLTKTLKYHPCERLVPLQCL----LSSYFD 448
Query: 307 PT 308
T
Sbjct: 449 ET 450
>YNL307c [G] KOG0658 Glycogen synthase kinase-3
Length = 375
Score = 150 bits (379), Expect = 4e-36
Identities = 107/327 (32%), Positives = 170/327 (51%), Gaps = 33/327 (10%)
Query: 28 VGMGAFGLVCSATDTLTSQ----PVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHENLIC 83
+G GAFG V A T + P AIKK+ P T + REL++L+ H N++
Sbjct: 41 IGRGAFGTVVQAYLTQDKKNWLGPFAIKKV--PAHTEYKS----RELQILRIADHPNIVK 94
Query: 84 LEDIF--LSPLEDIYF-------VTELQGTDLHRLLQTR-PLEKQFVQYFLYQILRGLKY 133
L+ F LSP ++ + + E +++R + + + + ++ + YQI RG+ Y
Sbjct: 95 LQYFFTHLSPQDNKVYQHLAMECLPETLQIEINRYVTNKLEMPLKHIRLYTYQIARGMLY 154
Query: 134 VHSAGVIHRDLKPSNILIN-ENCDLKICDFGLARIQDPQMTG--YVSTRYYRAPEIMLTW 190
+H GV HRD+KPSN+L++ E LKICDFG A+ + Y+ +R+YRAPE+++
Sbjct: 155 LHGLGVCHRDIKPSNVLVDPETGVLKICDFGSAKKLEHNQPSISYICSRFYRAPELIIGC 214
Query: 191 QKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVI--DTICSENT 248
+Y ++DIW GC+ EM+ GK +F G++ + Q I LLG P K I +
Sbjct: 215 TQYTTQIDIWGLGCVMGEMLIGKAIFQGQEPLLQLREIAKLLGPPDKRFIFFSNPAYDGP 274
Query: 249 LKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPYLSPY-HDP 307
L F F + PD IDLL K+LV++P++R++ LAH + + +D
Sbjct: 275 LFSKPLFSGSSQQRFEKYFGHSGPDGIDLLMKILVYEPQQRLSPRRILAHQFFNELRNDD 334
Query: 308 T------DEPIAEAKFDWNFNDADLPV 328
T EPI ++FND +L +
Sbjct: 335 TFLPRGFTEPIKLPNL-FDFNDFELQI 360
>YKL139w [D] KOG0600 Cdc2-related protein kinase
Length = 528
Score = 150 bits (378), Expect = 5e-36
Identities = 95/309 (30%), Positives = 156/309 (49%), Gaps = 25/309 (8%)
Query: 19 TNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRH 78
T+ Y + VG G +G V A +T T + VA+KK+ + RE+KLL+ H
Sbjct: 180 TSVYLRIMQVGEGTYGKVYKAKNTNTEKLVALKKLRLQGEREGFPITSIREIKLLQSFDH 239
Query: 79 ENLICLEDIFLSPLEDIYFVTELQGTDLHRLLQTRPLEKQFVQ--YFLYQILRGLKYVHS 136
N+ +++I + + +Y + E DL LL + ++ Q + Q+L G++Y+H
Sbjct: 240 PNVSTIKEIMVESQKTVYMIFEYADNDLSGLLLNKEVQISHSQCKHLFKQLLLGMEYLHD 299
Query: 137 AGVIHRDLKPSNILINENCDLKICDFGLARIQDPQM--TGYVSTRYYRAPEIMLTWQKYN 194
++HRD+K SNILI+ +LKI DFGLAR + + T V T +YR PE++L Y
Sbjct: 300 NKILHRDVKGSNILIDNQGNLKITDFGLARKMNSRADYTNRVITLWYRPPELLLGTTNYG 359
Query: 195 VEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDT---------ICS 245
EVD+W GC+ E+ +F G + + Q I ++G+P + T I
Sbjct: 360 TEVDMWGCGCLLVELFNKTAIFQGSNELEQIESIFKIMGTPTINSWPTLYDMPWFFMIMP 419
Query: 246 ENTLKFVTSLPHRDPVPFSSRFQNLEPDA--IDLLEKMLVFDPKKRITAADALAHPYLSP 303
+ T K+V + FS +F+++ P + + L +L +D KR +A +AL Y
Sbjct: 420 QQTTKYVNN--------FSEKFKSVLPSSKCLQLAINLLCYDQTKRFSATEALQSDYFK- 470
Query: 304 YHDPTDEPI 312
+P EP+
Sbjct: 471 -EEPKPEPL 478
>Hs4502747 [D] KOG0669 Cyclin T-dependent kinase CDK9
Length = 372
Score = 150 bits (378), Expect = 5e-36
Identities = 102/309 (33%), Positives = 155/309 (50%), Gaps = 21/309 (6%)
Query: 20 NRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHE 79
++Y L +G G FG V A T Q VA+KK++ RE+K+L+ L+HE
Sbjct: 17 SKYEKLAKIGQGTFGEVFKARHRKTGQKVALKKVLMENEKEGFPITALREIKILQLLKHE 76
Query: 80 NLICLEDIF---LSPLE----DIYFVTELQGTDLHRLLQTRPLEKQF--VQYFLYQILRG 130
N++ L +I SP IY V + DL LL ++ ++ + +L G
Sbjct: 77 NVVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNVLVKFTLSEIKRVMQMLLNG 136
Query: 131 LKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARI-------QDPQMTGYVSTRYYRA 183
L Y+H ++HRD+K +N+LI + LK+ DFGLAR Q + T V T +YR
Sbjct: 137 LYYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFSLAKNSQPNRYTNRVVTLWYRP 196
Query: 184 PEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDV---I 240
PE++L + Y +D+W AGCI AEM P+ G HQ ++I+ L GS +V +
Sbjct: 197 PELLLGERDYGPPIDLWGAGCIMAEMWTRSPIMQGNTEQHQLALISQLCGSITPEVWPNV 256
Query: 241 DTICSENTLKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPY 300
D L+ V + V + +P A+DL++K+LV DP +RI + DAL H +
Sbjct: 257 DNYELYEKLELVKG--QKRKVKDRLKAYVRDPYALDLIDKLLVLDPAQRIDSDDALNHDF 314
Query: 301 LSPYHDPTD 309
P+D
Sbjct: 315 FWSDPMPSD 323
>CE29612 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 426
Score = 149 bits (377), Expect = 6e-36
Identities = 99/311 (31%), Positives = 154/311 (48%), Gaps = 35/311 (11%)
Query: 17 EITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHL 76
++ + Y ++ +G G++ V L VA+K+I F L RE LL++L
Sbjct: 103 DVNDLYKRIDKLGEGSYATVYKCESKLDGSIVALKEIKLQFQEG-LPFTAIREASLLRNL 161
Query: 77 RHENLICLEDIFLSPLEDIYFVTELQGTDLHRLLQTRP--LEKQFVQYFLYQILRGLKYV 134
RH N++ L DIF + FV E DL + L+ L+ ++ L+Q+LRGL +
Sbjct: 162 RHANIVSLHDIFYQH-HQLTFVFEYMKMDLSKYLEQNVYGLDSIDIKLLLFQLLRGLDFC 220
Query: 135 HSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQMTGY---VSTRYYRAPEIMLTWQ 191
H ++HRDLKP N+L++E+ LK+ DFGLAR + Y V T +YR P++++
Sbjct: 221 HRKKILHRDLKPQNLLLDEDGVLKLADFGLARAKSVPSRTYSHEVVTLWYRPPDVLMGST 280
Query: 192 KYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVH------QFSIITDLLGSPPKDVIDTICS 245
Y+ +D+W GCIFAE+ G LFPG H Q +I + G+P
Sbjct: 281 DYSTSLDMWGVGCIFAEICTGAALFPGSKDSHYPGTKDQLDMIFSIRGTP---------D 331
Query: 246 ENTLKFVTSLPHRDPVPFSSRFQNLEPDAI------------DLLEKMLVFDPKKRITAA 293
E V +LP P F R++ L A+ +LL +L P+ R++AA
Sbjct: 332 EKKWPEVKTLPGYTPELF-PRYRELSFIAVNPMFTKILKTGQELLGMLLQLRPESRVSAA 390
Query: 294 DALAHPYLSPY 304
A+ HPY + +
Sbjct: 391 SAMLHPYFASF 401
>7302908 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 317
Score = 149 bits (375), Expect = 1e-35
Identities = 106/291 (36%), Positives = 143/291 (48%), Gaps = 17/291 (5%)
Query: 22 YTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLR---H 78
Y LN +G GA+G V A D +T VA+KK+ + + + T RE+ LLK L H
Sbjct: 26 YQELNIIGEGAYGTVYRARDVITGNIVALKKVRISLNENGVPMSTLREISLLKQLNASNH 85
Query: 79 ENLICLEDIFLSPLED----IYFVTELQGTDLHRLLQTRP---LEKQFVQYFLYQILRGL 131
N++ L ++ D I V E DL L+ P + +Q ++L G+
Sbjct: 86 ANIVKLYEVCQFLERDGQLLILLVFEHVEQDLSDLIDRLPKSGMSPPTIQRLSRELLTGV 145
Query: 132 KYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQM--TGYVSTRYYRAPEIMLT 189
++HS +IHRDLKP N+L++ LKI DFGLA+ +M T V T +YRAPE++L
Sbjct: 146 DFLHSHRIIHRDLKPQNLLVSSQGHLKIADFGLAKTYGSEMKLTSVVVTLWYRAPEVLLA 205
Query: 190 WQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTL 249
Q YN VDIWSA CI EM + LFPG +Q I +L G P + S
Sbjct: 206 -QPYNSTVDIWSAACIIFEMFNRRALFPGTSEKNQLDRIFELTGRPTEQQWPQTISVALE 264
Query: 250 KFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPY 300
F P R P +L A DLL KML +D R +A L H Y
Sbjct: 265 HF----PQRHPKRPKDFCPHLCKYADDLLNKMLSYDLHLRPSALACLEHDY 311
>CE19749 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 398
Score = 147 bits (372), Expect = 2e-35
Identities = 108/329 (32%), Positives = 162/329 (48%), Gaps = 42/329 (12%)
Query: 13 GTVFEITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLA--KRTYREL 70
GT F + RY N+ P V A D + +PV IKK+M P S +R REL
Sbjct: 12 GTFFTVPVRYVNVQPFQFDK-PFVVHAFDQVLGRPVVIKKVMLPDSLHDRQPWRRAQREL 70
Query: 71 KLLKHLRHENLICLEDIFL---SPLE--DIYFVTELQGTDLHRLLQTRPLE--KQFVQYF 123
+ ++ +N++ + F +PL+ + Y V E + L + E + V+
Sbjct: 71 NCMLNIEDDNVVKMYSTFTPAENPLKMTEFYIVREYMHGTMKNLSASTFNEGGHRTVKSI 130
Query: 124 LYQILRGLKYVHSAGVIHR--------------DLKPSNILINENCDLKICDFGLARIQD 169
+ I RG++Y+H+ + HR DLKP NIL+N+ D+K+CDFG + +D
Sbjct: 131 FFDICRGVQYLHAMRISHRYFISKLVYFVTERQDLKPENILMNQEGDVKLCDFGHSNKED 190
Query: 170 PQM-TGYVSTRYYRAPEIML-TWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSI 227
P T Y+ R+YRAPEI+ T VDIWS GCI AE++ G LF GKDH+ QF +
Sbjct: 191 PTSNTPYIVQRFYRAPEIICETTDNNKTNVDIWSLGCILAELLTGHVLFRGKDHIDQFIL 250
Query: 228 ITDLLGSPPKDVIDTICSENTLKFVTSL---PHRDPVPFSSRFQN--------LEPD--- 273
+ LG+ + +E+ F+ ++ P+ F SRF + EP
Sbjct: 251 MVQFLGNAGPSFYSQM-NEHARNFLLRYNLDQYQAPINFYSRFPDTVFQGVLQFEPKECD 309
Query: 274 -AIDLLEKMLVFDPKKRITAADALAHPYL 301
+ DLL +MLV +P R+ L+HPYL
Sbjct: 310 MSRDLLFRMLVINPDDRLNIQMVLSHPYL 338
>CE01761 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 719
Score = 147 bits (371), Expect = 3e-35
Identities = 107/316 (33%), Positives = 160/316 (49%), Gaps = 15/316 (4%)
Query: 20 NRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELK-LLKHLRH 78
+ Y +N V G FG+V D T + VA+K++ RE+ LLK H
Sbjct: 354 DEYECVNRVDEGTFGVVYRGKDKRTDEIVALKRLKMEKEKEGFPITALREINMLLKAGNH 413
Query: 79 ENLICLEDIFL-SPLEDIYFVTELQGTDLHRLLQTRPLE-KQFV----QYFLYQILRGLK 132
N++ +++I L S ++ IY E D+ LL T K+F + L Q+L G++
Sbjct: 414 PNIVNVKEILLGSNMDKIYMAMEFVEHDMKSLLDTMSRRNKRFSIGEQKTLLQQLLSGIE 473
Query: 133 YVHSAGVIHRDLKPSNILINENCDLKICDFGLAR-IQDP--QMTGYVSTRYYRAPEIMLT 189
++H ++HRDLK SN+L++ LKI DFGLAR DP + T V T +YR+PE++L
Sbjct: 474 HMHKLWILHRDLKTSNLLMSHKGILKIADFGLAREYGDPLKKFTSIVVTLWYRSPELLLG 533
Query: 190 WQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTL 249
+ Y+ VD+WS GCI AE I KPLFPG+ + Q I +G+P + + + +
Sbjct: 534 TRLYSTPVDMWSVGCIMAEFILLKPLFPGRGELEQIKKIFMEMGTPTESIWPGVTELDGW 593
Query: 250 KFVT--SLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPYLS--PYH 305
K +T P+ + L LL +L DPK R +A AL H + + PY
Sbjct: 594 KALTFEKYPYNQLRKRFLAGRLLNDTGFKLLNGLLTLDPKNRFSATQALDHEWFTEEPYP 653
Query: 306 DPTDE-PIAEAKFDWN 320
P +E P AK + N
Sbjct: 654 VPPEEFPTFPAKSEQN 669
>Hs7706059 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 455
Score = 146 bits (369), Expect = 5e-35
Identities = 100/287 (34%), Positives = 146/287 (50%), Gaps = 9/287 (3%)
Query: 22 YTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHENL 81
Y L VG G++G V T Q VAIK + SV K RE+K LK HENL
Sbjct: 4 YETLGKVGEGSYGTVMKCKHKNTGQIVAIKIFYERPEQSV-NKIAMREIKFLKQFHHENL 62
Query: 82 ICLEDIFLSPLEDIYFVTE-LQGTDLHRLLQ-TRPLEKQFVQYFLYQILRGLKYVHSAGV 139
+ L ++F + I+ V E + T L L LE + ++ +L+QILR + Y+HS +
Sbjct: 63 VNLIEVFRQK-KKIHLVFEFIDHTVLDELQHYCHGLESKRLRKYLFQILRAIDYLHSNNI 121
Query: 140 IHRDLKPSNILINENCDLKICDFGLAR---IQDPQMTGYVSTRYYRAPEIMLTWQKYNVE 196
IHRD+KP NIL++++ K+CDFG AR T YV+TR+YRAPE++L Y
Sbjct: 122 IHRDIKPENILVSQSGITKLCDFGFARTLAAPGDIYTDYVATRWYRAPELVLKDTSYGKP 181
Query: 197 VDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLKFVTSLP 256
VDIW+ GC+ EM G P P + I +G+ + I S++ + LP
Sbjct: 182 VDIWALGCMIIEMATGNPYLPSSSDLDLLHKIVLKVGNLSPH-LQNIFSKSPIFAGVVLP 240
Query: 257 H-RDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPYLS 302
+ P ++ L D++ L DP RI+++D L H Y +
Sbjct: 241 QVQHPKNARKKYPKLNGLLADIVHACLQIDPADRISSSDLLHHEYFT 287
>Hs4503095 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 391
Score = 146 bits (368), Expect = 7e-35
Identities = 97/292 (33%), Positives = 159/292 (54%), Gaps = 20/292 (6%)
Query: 22 YTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRH-EN 80
Y + +G G + V A + ++ V +K I+KP V K+ RE+K+L++LR N
Sbjct: 39 YQLVRKLGRGKYSEVFEAINITNNEKVVVK-ILKP----VKKKKIKREIKILENLRGGPN 93
Query: 81 LICLEDIFLSPLE--DIYFVTELQGTDLHRLLQTRPLEKQFVQYFLYQILRGLKYVHSAG 138
+I L DI P+ + TD +L QT L +++++Y+IL+ L Y HS G
Sbjct: 94 IITLADIVKDPVSRTPALVFEHVNNTDFKQLYQT--LTDYDIRFYMYEILKALDYCHSMG 151
Query: 139 VIHRDLKPSNILI-NENCDLKICDFGLARIQDP--QMTGYVSTRYYRAPEIMLTWQKYNV 195
++HRD+KP N++I +E+ L++ D+GLA P + V++RY++ PE+++ +Q Y+
Sbjct: 152 IMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDY 211
Query: 196 EVDIWSAGCIFAEMIEGK-PLFPGKDHVHQFSIITDLLGSPP-KDVIDTICSENTLKFVT 253
+D+WS GC+ A MI K P F G D+ Q I +LG+ D ID E +F
Sbjct: 212 SLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFND 271
Query: 254 SLPHR-----DPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPY 300
L + S + P+A+D L+K+L +D + R+TA +A+ HPY
Sbjct: 272 ILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPY 323
>7296346 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 952
Score = 146 bits (368), Expect = 7e-35
Identities = 93/299 (31%), Positives = 153/299 (51%), Gaps = 14/299 (4%)
Query: 25 LNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHENLICL 84
LN + G +G+V A D T++ VA+K++ + RE+ L +H N++ +
Sbjct: 561 LNRIEEGTYGVVYRAKDKRTNEIVALKRLKMEKEKEGFPITSLREINTLLKGQHPNIVTV 620
Query: 85 EDIFL-SPLEDIYFVTELQGTDLHRLLQTRPLEKQF-----VQYFLYQILRGLKYVHSAG 138
+I + S ++ I+ V + DL L++T KQ V+ Q+LR + ++H
Sbjct: 621 REIVVGSNMDKIFIVMDYVEHDLKSLMETMKNRKQSFFPGEVKCLTQQLLRAVAHLHDNW 680
Query: 139 VIHRDLKPSNILINENCDLKICDFGLARIQDPQMTGYVS---TRYYRAPEIMLTWQKYNV 195
++HRDLK SN+L++ LK+ DFGLAR + Y S T +YRAPE++L Y+
Sbjct: 681 ILHRDLKTSNLLLSHKGILKVGDFGLAREYGSPIKKYTSLVVTLWYRAPELLLCSPVYST 740
Query: 196 EVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDV----IDTICSENTLKF 251
+D+WS GCIFAE ++ PLFPGK + + + I LG+P + + + +N L
Sbjct: 741 PIDVWSVGCIFAEFLQMLPLFPGKSEIDELNRIFKELGTPNEKIWPGYTELPAVKNMLSQ 800
Query: 252 VTSLPHRDPVPFSSRFQNLEPD-AIDLLEKMLVFDPKKRITAADALAHPYLSPYHDPTD 309
+ FQ + + LL+ +L +DPK+R++A AL H + P D
Sbjct: 801 NSQFTEYPVSQLRKHFQEKTSEMGLSLLQGLLTYDPKQRLSADAALKHGFFKELPLPID 859
>Hs7706549 [D] KOG0600 Cdc2-related protein kinase
Length = 1490
Score = 145 bits (367), Expect = 9e-35
Identities = 92/300 (30%), Positives = 149/300 (49%), Gaps = 22/300 (7%)
Query: 20 NRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHE 79
+++ + +G G +G V A D T + VA+KK+ RE+K+L+ L H
Sbjct: 725 DKFDIIGIIGEGTYGQVYKARDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLIHR 784
Query: 80 NLICLEDIFLSPLEDI---------YFVTELQGTDLHRLLQTRPLE--KQFVQYFLYQIL 128
+++ +++I + + Y V E DL LL++ + + ++ F+ Q++
Sbjct: 785 SVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFMKQLM 844
Query: 129 RGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQ----MTGYVSTRYYRAP 184
GL+Y H +HRD+K SNIL+N + +K+ DFGLAR+ + + T V T +YR P
Sbjct: 845 EGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLWYRPP 904
Query: 185 EIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTIC 244
E++L ++Y +D+WS GCI E+ KP+F + Q +I+ L GSP V +
Sbjct: 905 ELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDVI 964
Query: 245 S---ENTLKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPYL 301
NT+K R F + A+DLL+ ML DP KR TA L +L
Sbjct: 965 KLPYFNTMKPKKQYRRR----LREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFL 1020
>ECU11g0960 [D] KOG0600 Cdc2-related protein kinase
Length = 329
Score = 145 bits (367), Expect = 9e-35
Identities = 92/288 (31%), Positives = 144/288 (49%), Gaps = 22/288 (7%)
Query: 22 YTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHENL 81
Y + +G G FG V A A+KK+ K L+ T RE+++L+ + H ++
Sbjct: 22 YEKIRIIGEGTFGQVILARKGRARY--ALKKVSK--EKEGLSVTTIREVQVLRAMGHPSI 77
Query: 82 ICLEDIFLSPLEDIYFVTELQGTDLHRLLQTRPLEKQFVQYFLYQILRGLKYVHSAGVIH 141
+ L ++ + P DIY V DL+R +++ + +++ YQI +G+ Y+HS G++H
Sbjct: 78 VRLIEVVVEPGGDIYMVFPYFPYDLNRFIRSNKMTCSEIKHIFYQIAQGVCYIHSKGIMH 137
Query: 142 RDLKPSNILINENCDLKICDFGLAR--IQDPQMTGYVSTRYYRAPEIMLTWQKYNVEVDI 199
RDLK +NIL+++ + I DFG+AR + T + T +YRAPEI+L Y VDI
Sbjct: 138 RDLKSANILLDQKLNASIADFGMARYTTKTGAYTPGMVTLWYRAPEILLGSSSYTYAVDI 197
Query: 200 WSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLKFVTSLP--- 256
WS GCI EM G +F G + Q ++ GS +EN+ V LP
Sbjct: 198 WSLGCILTEMYLGHMIFQGSTEMLQLEMVIHACGS---------INENSYPGVQDLPGFR 248
Query: 257 ----HRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPY 300
+ P + + A++L+ KML DP KRIT + Y
Sbjct: 249 NFRLPQSPRRIEGIIRKHDASAVELVSKMLCLDPSKRITVEQVVGSKY 296
>SPBC32H8.10 [D] KOG0600 Cdc2-related protein kinase
Length = 591
Score = 145 bits (366), Expect = 1e-34
Identities = 96/310 (30%), Positives = 155/310 (49%), Gaps = 28/310 (9%)
Query: 22 YTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHENL 81
Y + +G G FG V + + A+K+I+ RE+K+LK ++HEN+
Sbjct: 36 YHLMEKLGEGTFGEVYKSQRRKDGKVYALKRILMHTEKEGFPITAIREIKILKSIKHENI 95
Query: 82 ICLEDIFLSPLE-------DIYFVTELQGTDLHRLLQTRPLE--KQFVQYFLYQILRGLK 132
I L D+ + + IY VT DL LL+ ++ + ++ ++ Q+ G K
Sbjct: 96 IPLSDMTVVRADKKHRRRGSIYMVTPYMDHDLSGLLENPSVKFTEPQIKCYMKQLFAGTK 155
Query: 133 YVHSAGVIHRDLKPSNILINENCDLKICDFGLARI--------QDP--------QMTGYV 176
Y+H ++HRDLK +N+LI+ + LKI DFGLAR+ ++P + TG V
Sbjct: 156 YLHDQLILHRDLKAANLLIDNHGILKIADFGLARVITEESYANKNPGLPPPNRREYTGCV 215
Query: 177 STRYYRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPP 236
TR+YR+PE++L ++Y +D+WS GCI AEM +G+P+ G + Q I L GSP
Sbjct: 216 VTRWYRSPELLLGERRYTTAIDMWSVGCIMAEMYKGRPILQGSSDLDQLDKIFRLCGSPT 275
Query: 237 KDVIDTICSENTLKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADAL 296
+ + + V S P P + F + L +L +P +R++A+ AL
Sbjct: 276 QATMPNWEKLPGCEGVRSFPSH-PRTLETAFFTFGKEMTSLCGAILTLNPDERLSASMAL 334
Query: 297 AHPYLS--PY 304
H Y + PY
Sbjct: 335 EHEYFTTPPY 344
>CE26988 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 308
Score = 145 bits (366), Expect = 1e-34
Identities = 90/288 (31%), Positives = 146/288 (50%), Gaps = 27/288 (9%)
Query: 18 ITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIM---KPFSTSVLAKRTYRELKLLK 74
++ RY + +G G F V A D + + VAIKKI + + + + RE+KLLK
Sbjct: 1 MSRRYDTIKHLGEGQFANVYLAQDLESGECVAIKKIKLGSREEAKDGINRTAIREIKLLK 60
Query: 75 HLRHENLICLEDIFLSPLEDIYFVTELQGTDLHRLLQTRP--LEKQFVQYFLYQILRGLK 132
+ H+N+I L D+ + I V + TDL +++ + L ++ Q+L GL+
Sbjct: 61 EIHHDNIIGLRDV-IGHRTSIQLVFDFMDTDLEHVIKDKEIILMPAHIKNITMQMLLGLE 119
Query: 133 YVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQMTGYVSTRYYRAPEIMLTWQK 192
++H ++HRDLKP+N+L+N+ G V TR+YRAPE++ +
Sbjct: 120 FLHVHWILHRDLKPNNLLMNK-------------------MGRVVTRWYRAPELLFGARS 160
Query: 193 YNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLKFV 252
Y V +DIWS GCI AE++ P+FPG+ + Q I ++LG P + + N+ +V
Sbjct: 161 YGVGIDIWSVGCIIAELLLRNPIFPGESDIDQLVKIFNILGCPTPETWPNMTEMNS--YV 218
Query: 253 TSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPY 300
P + + + F D +DL+ M FDP KR+T +L Y
Sbjct: 219 IIKPQTEYMALNYYFSAAPQDLLDLMAGMWTFDPIKRLTCTQSLQMEY 266
>Hs17461944 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 385
Score = 145 bits (365), Expect = 2e-34
Identities = 94/298 (31%), Positives = 152/298 (50%), Gaps = 15/298 (5%)
Query: 21 RYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHEN 80
+Y L G G++G+V + + Q VA+KK ++ V+ K RE+++LK L+H N
Sbjct: 3 KYEKLAKTGEGSYGVVFKCRNKTSGQVVAVKKFVESEDDPVVKKIALREIRMLKQLKHPN 62
Query: 81 LICLEDIFLSPLEDIYFVTELQGTDLHRLLQTRP--LEKQFVQYFLYQILRGLKYVHSAG 138
L+ L ++F + ++ V E L L+ P ++ + L + +
Sbjct: 63 LVNLIEVFRRKRK-MHLVFEYCDHTLLNELERNPNGMDSDSIVGRLRSVADRSRLAPKNN 121
Query: 139 ------VIHRDLKPSNILINENCDLKICDFGLARIQDP--QMTGYVSTRYYRAPEIMLTW 190
IHRD+KP NILI + +KICDFG A+I P T YV+TR+YRAPE+++
Sbjct: 122 QIMILQCIHRDIKPENILITKQGIIKICDFGFAQILIPGDAYTDYVATRWYRAPELLVGD 181
Query: 191 QKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGS-PPKDVIDTICSENTL 249
+Y VDIW+ GC+FAE++ G+PL+PGK V Q +I LG P+ +I N
Sbjct: 182 TQYGSSVDIWAIGCVFAELLTGQPLWPGKSDVDQLYLIIRTLGKLIPRH--QSIFKSNGF 239
Query: 250 KFVTSLPH-RDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPYLSPYHD 306
S+P D +F ++ P A++ ++ L +P R+T + L Y + +
Sbjct: 240 FHGISIPEPEDMETLEEKFSDVHPVALNFMKGCLKMNPDDRLTCSQLLESSYFDSFQE 297
>YDL108w [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 306
Score = 144 bits (364), Expect = 2e-34
Identities = 94/298 (31%), Positives = 149/298 (49%), Gaps = 6/298 (2%)
Query: 17 EITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHL 76
++ YT VG G + +V T + +AIK+I L RE+K L+ +
Sbjct: 2 KVNMEYTKEKKVGEGTYAVVYLGCQHSTGRKIAIKEIKTSEFKDGLDMSAIREVKYLQEM 61
Query: 77 RHENLICLEDIFLSPLEDIYFVTELQGTDLHRLLQTRPL--EKQFVQYFLYQILRGLKYV 134
+H N+I L DIF++ +++ V E TDL +++ + + ++ ++ LRG+ +
Sbjct: 62 QHPNVIELIDIFMA-YDNLNLVLEFLPTDLEVVIKDKSILFTPADIKAWMLMTLRGVYHC 120
Query: 135 HSAGVIHRDLKPSNILINENCDLKICDFGLAR-IQDPQ--MTGYVSTRYYRAPEIMLTWQ 191
H ++HRDLKP+N+L + + +K+ DFGLAR I P +T V TR+YRAPE++ +
Sbjct: 121 HRNFILHRDLKPNNLLFSPDGQIKVADFGLARAIPAPHEILTSNVVTRWYRAPELLFGAK 180
Query: 192 KYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLKF 251
Y +DIWS G IFAE++ P PG++ V Q + LG+P + S T
Sbjct: 181 HYTSAIDIWSVGVIFAELMLRIPYLPGQNDVDQMEVTFRALGTPTDRDWPEVSSFMTYNK 240
Query: 252 VTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPYLSPYHDPTD 309
+ P RF A+D + ML +P+KR TA L Y P+D
Sbjct: 241 LQIYPPPSRDELRKRFIAASEYALDFMCGMLTMNPQKRWTAVQCLESDYFKELPPPSD 298
>Hs14110390 [D] KOG0600 Cdc2-related protein kinase
Length = 1452
Score = 144 bits (364), Expect = 2e-34
Identities = 93/301 (30%), Positives = 149/301 (48%), Gaps = 24/301 (7%)
Query: 20 NRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHE 79
+++ + +G G +G V A D T + VA+KK+ RE+K+L+ L H+
Sbjct: 703 DKFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTHQ 762
Query: 80 NLICLEDIFLSPLED----------IYFVTELQGTDLHRLLQTRPLE--KQFVQYFLYQI 127
++I +++I ++ ED Y V E DL LL++ + + ++ F+ Q+
Sbjct: 763 SIINMKEI-VTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQL 821
Query: 128 LRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQ----MTGYVSTRYYRA 183
+ GL Y H +HRD+K SNIL+N +K+ DFGLAR+ + T V T +YR
Sbjct: 822 MEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRPYTNKVITLWYRP 881
Query: 184 PEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTI 243
PE++L ++Y +D+WS GCI E+ KP+F + Q +I+ + GSP V +
Sbjct: 882 PELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELISRICGSPCPAVWPDV 941
Query: 244 CS---ENTLKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPY 300
NT+K + F + A+DL + ML DP KR TA AL +
Sbjct: 942 IKLPYFNTMKPKKQYRRK----LREEFVFIPAAALDLFDYMLALDPSKRCTAEQALQCEF 997
Query: 301 L 301
L
Sbjct: 998 L 998
>Hs14110387 [D] KOG0600 Cdc2-related protein kinase
Length = 1512
Score = 144 bits (364), Expect = 2e-34
Identities = 93/301 (30%), Positives = 149/301 (48%), Gaps = 24/301 (7%)
Query: 20 NRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHE 79
+++ + +G G +G V A D T + VA+KK+ RE+K+L+ L H+
Sbjct: 703 DKFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTHQ 762
Query: 80 NLICLEDIFLSPLED----------IYFVTELQGTDLHRLLQTRPLE--KQFVQYFLYQI 127
++I +++I ++ ED Y V E DL LL++ + + ++ F+ Q+
Sbjct: 763 SIINMKEI-VTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQL 821
Query: 128 LRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQ----MTGYVSTRYYRA 183
+ GL Y H +HRD+K SNIL+N +K+ DFGLAR+ + T V T +YR
Sbjct: 822 MEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRPYTNKVITLWYRP 881
Query: 184 PEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTI 243
PE++L ++Y +D+WS GCI E+ KP+F + Q +I+ + GSP V +
Sbjct: 882 PELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELISRICGSPCPAVWPDV 941
Query: 244 CS---ENTLKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPY 300
NT+K + F + A+DL + ML DP KR TA AL +
Sbjct: 942 IKLPYFNTMKPKKQYRRK----LREEFVFIPAAALDLFDYMLALDPSKRCTAEQALQCEF 997
Query: 301 L 301
L
Sbjct: 998 L 998
>CE08727 [G] KOG0658 Glycogen synthase kinase-3
Length = 367
Score = 144 bits (363), Expect = 3e-34
Identities = 100/330 (30%), Positives = 160/330 (48%), Gaps = 49/330 (14%)
Query: 17 EITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHL 76
E+ ++TNL +G G+FG V A +P+AIKKI V + REL ++ +
Sbjct: 32 EVEIQFTNLQLIGTGSFGAVYKAVLRENDEPIAIKKI------KVDDRFKSRELTIMHEM 85
Query: 77 RHENLICLEDIFLSPLED-IYFVTELQGTDL---HRLL--QTRPLEKQFVQYFLYQILRG 130
H N+I L ++ E+ + FV E DL HR + + ++ +++Q+LRG
Sbjct: 86 DHPNIIRLLYYYVMQQENCLNFVMEFMPKDLAYVHRQFAHNDKQMPAYSIKLYMFQLLRG 145
Query: 131 LKYVHSAGVIHRDLKPSNILINE-NCDLKICDFGLARI---QDPQMTGYVSTRYYRAPEI 186
+ ++H ++HRD+KP N+L++E N LKICDFG A+ +P +T Y+ +RYYRAPE+
Sbjct: 146 IGFLHLHNIVHRDIKPKNLLVDESNGILKICDFGSAKRLEKNEPNIT-YICSRYYRAPEL 204
Query: 187 MLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVI------ 240
+ + Y+ +D WS G + E++ P+F V ++ G+P K+ +
Sbjct: 205 IFGSKNYDTSIDTWSVGTVVGELLHNSPIFLADSAVDILALQIKAFGTPSKEDMAKWNYE 264
Query: 241 ------DTICSENTLKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAAD 294
DTI KF+ + L ++LL ++ DPK RI +
Sbjct: 265 YVHIPYDTITGVGIQKFIG--------------RKLSLSTLELLNSLMKMDPKLRIKPYE 310
Query: 295 ALAHPYLSPYHD-----PTDEPIAEAKFDW 319
AL PY D P+ PI FDW
Sbjct: 311 ALTLPYFDDLRDPHYKLPSGAPIPPL-FDW 339
>Hs18581346 [T] KOG0660 Mitogen-activated protein kinase
Length = 377
Score = 143 bits (361), Expect = 4e-34
Identities = 100/316 (31%), Positives = 156/316 (48%), Gaps = 61/316 (19%)
Query: 16 FEITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKH 75
F++ + Y +L P+G G L SA D + VAIKKI+ SV K E+K+++
Sbjct: 44 FDLDSTYMDLKPLGCGGNYLFFSAVDNDCDKRVAIKKIVLTNPQSV--KHALCEIKIIRR 101
Query: 76 LRHENLICLEDI-------------FLSPLEDIYFVTELQGTDLHRLLQTRPLEKQFVQY 122
L H+N++ + +I L+ L +Y V E TDL ++L+ PL ++ +
Sbjct: 102 LDHDNIVKVFEIPGPSGSQLTDDVGSLTELNSVYIVQEYMKTDLSKVLEQGPLLEEHARL 161
Query: 123 FLYQILRGLKYVHSAGVIHRDLKPSNILIN-ENCDLKICDFGLARIQDPQMTGYVSTRYY 181
F+YQ+LRGLKY+HSA V+HRDLKP+N+ IN E+ LKI DFGLARI DP +R +
Sbjct: 162 FMYQLLRGLKYIHSANVLHRDLKPTNLFINTEDLVLKIGDFGLARIMDPHY-----SRAH 216
Query: 182 RAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVID 241
++ LT +E P+ +D S+I + + +
Sbjct: 217 ELEQMQLT--------------------LESIPVAHEEDRQELLSVIPVYIRNHMTE--- 253
Query: 242 TICSENTLKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPYL 301
PH+ P + + +A++ LE++L F P + A +AL+HPY+
Sbjct: 254 --------------PHK---PLTQLLPGISREALNFLEQILTFSPMDWLIAEEALSHPYM 296
Query: 302 SPYHDPTDEPIAEAKF 317
S P D+PI+ F
Sbjct: 297 SICSFPMDKPISSHPF 312
>ECU02g1450 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 308
Score = 143 bits (361), Expect = 4e-34
Identities = 93/276 (33%), Positives = 141/276 (50%), Gaps = 7/276 (2%)
Query: 35 LVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHENLICLEDIFLSPLED 94
LV S T + PVAIKKI T RE+K LK + + ++ L D F+ +
Sbjct: 31 LVSSGT-RIEDVPVAIKKIKPTKYTQGHEISAIREIKSLKRIDSKYVVRLIDTFVYD-KC 88
Query: 95 IYFVTELQGTDLHRLLQT--RPLEKQFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILIN 152
++ V E T+L +++ + + ++ ++ +LRG+ H +IHRD+KP+NILI
Sbjct: 89 VHIVLEYVETNLENVIRNSDKIIMPGDIKAWILMVLRGVYECHRLFIIHRDIKPNNILIT 148
Query: 153 ENCDLKICDFGLARIQDPQMTGYVSTRYYRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEG 212
+K+ DFGL R +MT TR+YRAPE+++ + Y VD+WS GC+FAE+
Sbjct: 149 SEGMVKLADFGLTRGIGNRMTPQAVTRWYRAPELLMGSRDYGSPVDMWSVGCVFAELFLR 208
Query: 213 KPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLKFVTSLPHRDPVPFSSRFQNLEP 272
PLF G + Q +I LG+P + + +TL + F
Sbjct: 209 VPLFAGDTDIQQLDMIFRALGTPVEREWPGV---STLPEFLDFQQYPKASLNGLFSAASS 265
Query: 273 DAIDLLEKMLVFDPKKRITAADALAHPYLSPYHDPT 308
DA+DLLEK+L +P RI+ DA+ HPY PT
Sbjct: 266 DALDLLEKLLTLNPCNRISCDDAIKHPYFKSSPPPT 301
>7289745 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 336
Score = 143 bits (360), Expect = 6e-34
Identities = 96/295 (32%), Positives = 158/295 (53%), Gaps = 20/295 (6%)
Query: 22 YTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRH-EN 80
Y + +G G + V A + T++ +K I+KP V K+ RE+K+L++LR N
Sbjct: 37 YQLVRKLGRGKYSEVFEAINITTTEKCVVK-ILKP----VKKKKIKREIKILENLRGGTN 91
Query: 81 LICLEDIFLSPLE--DIYFVTELQGTDLHRLLQTRPLEKQFVQYFLYQILRGLKYVHSAG 138
+I L + P+ + TD +L QT L ++Y+L+++L+ L Y HS G
Sbjct: 92 IITLLAVVKDPVSRTPALIFEHVNNTDFKQLYQT--LTDYEIRYYLFELLKALDYCHSMG 149
Query: 139 VIHRDLKPSNILI-NENCDLKICDFGLARIQDP--QMTGYVSTRYYRAPEIMLTWQKYNV 195
++HRD+KP N++I +EN L++ D+GLA P + V++RY++ PE+++ +Q Y+
Sbjct: 150 IMHRDVKPHNVMIDHENRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDY 209
Query: 196 EVDIWSAGCIFAEMIEGK-PLFPGKDHVHQFSIITDLLGSP------PKDVIDTICSENT 248
+D+WS GC+ A MI K P F G D+ Q I +LG+ K ID +
Sbjct: 210 SLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEELYAYLDKYNIDLDPRFHD 269
Query: 249 LKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPYLSP 303
+ S + S + P+A+D L+K+L +D R+TA +A+AHPY P
Sbjct: 270 ILQRHSRKRWERFVHSDNQHLVSPEALDFLDKLLRYDHVDRLTAREAMAHPYFLP 324
>YOL128c [G] KOG0658 Glycogen synthase kinase-3
Length = 375
Score = 142 bits (357), Expect = 1e-33
Identities = 95/301 (31%), Positives = 152/301 (49%), Gaps = 31/301 (10%)
Query: 28 VGMGAFGLVCSATDTLTS----QPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHENLIC 83
+G G+FG V + + S P AIK+++K L EL++L+++RH NL+
Sbjct: 47 IGHGSFGTVTQSILSSNSIEWLGPYAIKRVVKSPKVQSL------ELEILQNIRHPNLVT 100
Query: 84 LEDIFLSPLED------------IYFVTELQGTDLHRLLQT-RPLEKQFVQYFLYQILRG 130
LE F S + ++ + +++H + + ++ + +QILR
Sbjct: 101 LEFFFESHCTTKDGGHLYQKNFVMEYIPQTLSSEIHEYFDNGSKMPTKHIKLYTFQILRA 160
Query: 131 LKYVHSAGVIHRDLKPSNILINENCDL-KICDFGLARIQDP--QMTGYVSTRYYRAPEIM 187
L +HS + H DLKPSNILI + + K+CDFG A+ D ++ Y +R+YRAPE++
Sbjct: 161 LLTLHSMSICHGDLKPSNILIIPSSGIAKVCDFGSAQRLDDNTELKTYFCSRFYRAPELL 220
Query: 188 LTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSEN 247
L + Y ++DIWS GCI EMI+G+PLF G Q I LLG PK I +N
Sbjct: 221 LNSKDYTTQIDIWSLGCIIGEMIKGQPLFKGDSANSQLEEIAKLLGRFPKSSI-----KN 275
Query: 248 TLKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPYLSPYHDP 307
+ + SL + F F ++E ++ L K+L +D +R A +AH + +
Sbjct: 276 SQELQDSLNDQKFKKFMHWFPSIEFFDVEFLLKVLTYDATERCDARQLMAHEFFDALRNE 335
Query: 308 T 308
T
Sbjct: 336 T 336
>Hs4503097 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 350
Score = 141 bits (356), Expect = 2e-33
Identities = 95/306 (31%), Positives = 164/306 (53%), Gaps = 20/306 (6%)
Query: 22 YTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRH-EN 80
Y + +G G + V A + ++ V +K I+KP V K+ RE+K+L++LR N
Sbjct: 40 YQLVRKLGRGKYSEVFEAINITNNERVVVK-ILKP----VKKKKIKREVKILENLRGGTN 94
Query: 81 LICLEDIFLSPLEDIYFVT--ELQGTDLHRLLQTRPLEKQFVQYFLYQILRGLKYVHSAG 138
+I L D P+ + + TD +L Q L +++++Y++L+ L Y HS G
Sbjct: 95 IIKLIDTVKDPVSKTPALVFEYINNTDFKQLYQI--LTDFDIRFYMYELLKALDYCHSKG 152
Query: 139 VIHRDLKPSNILI-NENCDLKICDFGLARIQDP--QMTGYVSTRYYRAPEIMLTWQKYNV 195
++HRD+KP N++I ++ L++ D+GLA P + V++RY++ PE+++ +Q Y+
Sbjct: 153 IMHRDVKPHNVMIDHQQKKLRLIDWGLAEFYHPAQEYNVRVASRYFKGPELLVDYQMYDY 212
Query: 196 EVDIWSAGCIFAEMI-EGKPLFPGKDHVHQFSIITDLLGSP------PKDVIDTICSENT 248
+D+WS GC+ A MI +P F G+D+ Q I +LG+ K ID N
Sbjct: 213 SLDMWSLGCMLASMIFRREPFFHGQDNYDQLVRIAKVLGTEELYGYLKKYHIDLDPHFND 272
Query: 249 LKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPYLSPYHDPT 308
+ S + S + P+A+DLL+K+L +D ++R+TA +A+ HPY P
Sbjct: 273 ILGQHSRKRWENFIHSENRHLVSPEALDLLDKLLRYDHQQRLTAKEAMEHPYFYPVVKEQ 332
Query: 309 DEPIAE 314
+P A+
Sbjct: 333 SQPCAD 338
>CE28918 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 406
Score = 141 bits (356), Expect = 2e-33
Identities = 91/288 (31%), Positives = 149/288 (51%), Gaps = 17/288 (5%)
Query: 28 VGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLR---HENLICL 84
+G GA+G V + A+K+IM + + RE+ ++KHL H N+I L
Sbjct: 108 LGKGAYGNVYRVRSLHDGKDYALKQIMISSKNEGIPQSVLREITVMKHLARKAHPNIISL 167
Query: 85 EDIF--LSPLEDIY---FVTELQGTDLHRLLQTRP--LEKQFVQYFLYQILRGLKYVHSA 137
+ +F L P+ I + E DLH L+ P + +Q ++ QI+R L ++H+
Sbjct: 168 KSVFHQLDPVRAILKINMIMERCDWDLHTFLRNIPRGVPEQQAKHVTAQIVRALDFLHTH 227
Query: 138 GVIHRDLKPSNILINENCDLKICDFGLAR--IQDPQMTGYVSTRYYRAPEIMLTWQKYNV 195
+IHRDLKP NIL+N + +K+ DFGL++ T V T +YR+PE++L YN
Sbjct: 228 SIIHRDLKPQNILLNRDQTVKLADFGLSKEYSNTTAFTTLVVTLWYRSPEVLLQ-SYYNS 286
Query: 196 EVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLKFVTSL 255
VD+W+ GCI +E+ +PLF G++ Q + I +G+P + ++ S
Sbjct: 287 TVDMWALGCIVSEIYCRQPLFVGQNEAEQLTDIFKKMGTP----VGKDWPSESVIARDSF 342
Query: 256 PHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPYLSP 303
P P + AI+ +++ L +D KR++A AL+HP+L P
Sbjct: 343 PQYRPTNLKDLSPQMSKQAIEFVQQCLRYDHSKRLSARGALSHPFLKP 390
>CE18608 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 342
Score = 141 bits (356), Expect = 2e-33
Identities = 91/288 (31%), Positives = 149/288 (51%), Gaps = 17/288 (5%)
Query: 28 VGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLR---HENLICL 84
+G GA+G V + A+K+IM + + RE+ ++KHL H N+I L
Sbjct: 44 LGKGAYGNVYRVRSLHDGKDYALKQIMISSKNEGIPQSVLREITVMKHLARKAHPNIISL 103
Query: 85 EDIF--LSPLEDIY---FVTELQGTDLHRLLQTRP--LEKQFVQYFLYQILRGLKYVHSA 137
+ +F L P+ I + E DLH L+ P + +Q ++ QI+R L ++H+
Sbjct: 104 KSVFHQLDPVRAILKINMIMERCDWDLHTFLRNIPRGVPEQQAKHVTAQIVRALDFLHTH 163
Query: 138 GVIHRDLKPSNILINENCDLKICDFGLAR--IQDPQMTGYVSTRYYRAPEIMLTWQKYNV 195
+IHRDLKP NIL+N + +K+ DFGL++ T V T +YR+PE++L YN
Sbjct: 164 SIIHRDLKPQNILLNRDQTVKLADFGLSKEYSNTTAFTTLVVTLWYRSPEVLLQ-SYYNS 222
Query: 196 EVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLKFVTSL 255
VD+W+ GCI +E+ +PLF G++ Q + I +G+P + ++ S
Sbjct: 223 TVDMWALGCIVSEIYCRQPLFVGQNEAEQLTDIFKKMGTP----VGKDWPSESVIARDSF 278
Query: 256 PHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPYLSP 303
P P + AI+ +++ L +D KR++A AL+HP+L P
Sbjct: 279 PQYRPTNLKDLSPQMSKQAIEFVQQCLRYDHSKRLSARGALSHPFLKP 326
>ECU07g1270 [G] KOG0658 Glycogen synthase kinase-3
Length = 334
Score = 141 bits (355), Expect = 2e-33
Identities = 94/303 (31%), Positives = 155/303 (51%), Gaps = 26/303 (8%)
Query: 13 GTVFEITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTY--REL 70
G V E+ RY + +G G+FG+V D + A+K++ + R Y REL
Sbjct: 49 GEVKEVRYRYVEM--IGRGSFGVVVKIMDDRHNF-FALKRVYQD--------RRYHNREL 97
Query: 71 KLLKHLRHENLICLEDIFLSPLED----IYFVTELQGTDLHRLLQT-RPLEKQFVQYFLY 125
+L + H N++ L F + + +T+ G +L ++ R +E + ++
Sbjct: 98 GILMEVDHPNIVRLVSYFHTDKTSSGAYLNIITDFVGMNLEEYIKANRGVETEEIRSVYR 157
Query: 126 QILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARI--QDPQMTGYVSTRYYRA 183
QIL GL+Y+H + HRD+KPSNILI+ N +KICD G A++ + Y+ +R+YRA
Sbjct: 158 QILEGLRYLHEKNICHRDMKPSNILIDTNGLVKICDLGSAKVIKSGERNITYICSRFYRA 217
Query: 184 PEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTI 243
PE +L +++Y+ ++DIWS GC+ AE P+F G + I +++ D+I
Sbjct: 218 PENLLDYKEYDFKIDIWSVGCVIAEFRHPGPIFKGDTSGSTLNRILEIVRVTSDDLIGLG 277
Query: 244 CSENTLKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPYLSP 303
C + LK + FS +PD +++LEK L F P KR TA++ L +
Sbjct: 278 CLKPDLKQGVGIRKYLEAFFS------DPDLLEVLEKSLAFSPCKRSTASELLRKQFFQQ 331
Query: 304 YHD 306
H+
Sbjct: 332 AHE 334
>7291442 [D] KOG0669 Cyclin T-dependent kinase CDK9
Length = 404
Score = 141 bits (355), Expect = 2e-33
Identities = 104/328 (31%), Positives = 157/328 (47%), Gaps = 21/328 (6%)
Query: 1 MSNEEFIRTQIFGTVFEITNRYTNLNPVGMGAFGLVCSATDTLTSQP-VAIKKIMKPFST 59
M +++I F E +N+Y + +G G FG V A + ++ VA+KK++
Sbjct: 30 MEKQKYIEDYDFPYCDE-SNKYEKVAKIGQGTFGEVFKAREKKGNKKFVAMKKVLMDNEK 88
Query: 60 SVLAKRTYRELKLLKHLRHENLICLEDIFLSPL-------EDIYFVTELQGTDLHRLLQT 112
RE+++L+ L+HEN++ L +I + Y V + DL LL
Sbjct: 89 EGFPITALREIRILQLLKHENVVNLIEICRTKATATNGYRSTFYLVFDFCEHDLAGLLSN 148
Query: 113 RPLEKQF--VQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARI--- 167
++ ++ + Q+L GL Y+HS ++HRD+K +N+LI ++ LK+ DFGLAR
Sbjct: 149 MNVKFSLGEIKKVMQQLLNGLYYIHSNKILHRDMKAANVLITKHGILKLADFGLARAFSI 208
Query: 168 ----QDPQMTGYVSTRYYRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVH 223
+ T V T +YR PE++L + Y VD+W AGCI AEM P+ G
Sbjct: 209 PKNESKNRYTNRVVTLWYRPPELLLGDRNYGPPVDMWGAGCIMAEMWTRSPIMQGNTEQQ 268
Query: 224 QFSIITDLLGSPPKDVIDTICSENTLKFVTSLPHRDPVPFSSRFQNLEPD--AIDLLEKM 281
Q + I+ L GS DV + E L LP R + D DLL+K+
Sbjct: 269 QLTFISQLCGSFTPDVWPGV-EELELYKSIELPKNQKRRVKERLRPYVKDQTGCDLLDKL 327
Query: 282 LVFDPKKRITAADALAHPYLSPYHDPTD 309
L DPKKRI A AL H + P+D
Sbjct: 328 LTLDPKKRIDADTALNHDFFWTDPMPSD 355
>SPBC8D2.19 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 559
Score = 140 bits (354), Expect = 3e-33
Identities = 106/318 (33%), Positives = 157/318 (49%), Gaps = 29/318 (9%)
Query: 1 MSNEEFIRT-QIFGTVFEITNRYTNLNPVGMGAFGLVCSATDTLTS---QPVAIKKIM-- 54
MSNE + +FE +RY +G G+FG V A + + VA+KK+
Sbjct: 1 MSNESIYSVLDLTQVIFE--DRYLVKQKLGDGSFGTVYLAQRKEKNGLYETVAVKKLKNS 58
Query: 55 -KPFSTSVLAKRTYRELKLLKHLRHENLICLEDIFLSPLEDIYFVTELQGTDLHRLL--- 110
KP L K L L K +H LI L + F+ P +I+ V E +L +L
Sbjct: 59 SKPKPKHELLKLR-ESLALRKISKHPCLIDLLETFMDPYRNIFLVMEFMDCNLFQLFKRR 117
Query: 111 QTRPLEKQFVQYFLYQILRGLKYVHSAGVIHRDLKPSNIL--------INENCDLKICDF 162
Q R K+ L QI+ G++++H G +HRD+KP NIL I+ +K+ DF
Sbjct: 118 QGRLFTKETAFNILLQIISGIEHIHKHGFMHRDIKPENILVKRISPKPISSRYSIKLGDF 177
Query: 163 GLAR--IQDPQMTGYVSTRYYRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKD 220
GLAR + +T YVSTR+YRAPE++L YN VD+++ GCI E+ KPLFPG++
Sbjct: 178 GLARPSVSSDPLTEYVSTRWYRAPELLLRSGSYNHSVDLYAFGCIVFEIYSLKPLFPGRN 237
Query: 221 HVHQFSIITDLLGSPPKDVIDTI-----CSENTLKFVTSLPHRDPVPFSSRF-QNLEPDA 274
Q + + ++LG+P D +DT+ E + LP P P QN
Sbjct: 238 ETDQLNRVCEILGNPGIDELDTLHYWSQAKELAKRLGFMLPPTKPYPIQKLLPQNCPEGH 297
Query: 275 IDLLEKMLVFDPKKRITA 292
++ +L ++P R TA
Sbjct: 298 AKMIPCLLAWNPDVRPTA 315
>CE19219 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 381
Score = 140 bits (353), Expect = 4e-33
Identities = 103/313 (32%), Positives = 151/313 (47%), Gaps = 28/313 (8%)
Query: 15 VFEITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKP--FSTSVLAKRTYRELKL 72
+F + NRY +L P G + A D ++ + V IKK++ P F +R REL
Sbjct: 11 LFIVPNRYVDLLPSQFGN-AMEVIAFDQISERRVVIKKVVLPENFDNWQHWRRAQRELFC 69
Query: 73 LKHLRHENLICLEDIF-----LSPLEDIYFVTELQGTDLHRLLQTRP--LEKQFVQYFLY 125
H++ EN + + I+ + + + Y V E +L + + P L+ + ++ +
Sbjct: 70 TLHIQEENFVKMYSIYTWVETVEEMREFYTVREYMDWNLRNFILSTPEKLDHKVIKSIFF 129
Query: 126 QILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQM-TGYVSTRYYRAP 184
+ ++Y+HS V HRDLKP N+LIN KI F A +DP + T Y+ R+YRAP
Sbjct: 130 DVCLAVQYMHSIRVGHRDLKPENVLINYEAIAKISGFAHANREDPFVNTPYIVQRFYRAP 189
Query: 185 EIML-TWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTI 243
EI+ T VDIWS GCI AE++ GK LF G+ + QF I LG+P +
Sbjct: 190 EILCETMDNNKPSVDIWSLGCILAELLTGKILFTGQTQIDQFFQIVRFLGNPDLSFYMQM 249
Query: 244 CSENTLKFVTSLP---HRDPVPFSSRFQN--------LEPD----AIDLLEKMLVFDPKK 288
++ F LP ++ P F N EP A DLL +MLV +P
Sbjct: 250 -PDSARTFFLGLPMNQYQKPTNIHEHFPNSLFLDTMISEPIDCDLARDLLFRMLVINPDD 308
Query: 289 RITAADALAHPYL 301
RI L HPYL
Sbjct: 309 RIDIQKILVHPYL 321
>CE03811 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 763
Score = 140 bits (353), Expect = 4e-33
Identities = 100/322 (31%), Positives = 161/322 (49%), Gaps = 22/322 (6%)
Query: 20 NRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELK-LLKHLRH 78
+ Y LN + G +G V +T T + VA+K+ RE+ LLK H
Sbjct: 397 SEYVILNVIAEGTYGEVFRGKNTRTDEVVALKRFKMEKEKEGFPITALREINMLLKAGAH 456
Query: 79 ENLICLEDIFL-SPLEDIYFVTELQGTDLHRLL-QTRPLEKQFV----QYFLYQILRGLK 132
EN++ +++I + S ++Y E D+ L+ + R ++F + + Q+L G++
Sbjct: 457 ENIVNVKEILVGSTKTEVYMAMEYVEHDVKSLIDKMRSRNQRFKTGQQKTLMSQLLSGIE 516
Query: 133 YVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDP--------QMTGYVSTRYYRAP 184
++H ++HRDLK SN+LI+ + LKI DFGLAR ++T V T +YR+P
Sbjct: 517 HMHKLWILHRDLKTSNLLISHSGILKIADFGLAREYGEARDIEKRMKLTPIVVTLWYRSP 576
Query: 185 EIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTIC 244
E++L + Y+ VD+WS GCI AE I KP+F G +Q I ++G+P + + I
Sbjct: 577 ELLLEPKTYSTPVDMWSIGCIMAEFIMMKPMFQGDSEPNQVHQIFQMMGTPTEQIWPDI- 635
Query: 245 SENTLKFVTSLPHRDPVPFSSRFQN---LEPDAIDLLEKMLVFDPKKRITAADALAHPYL 301
E + + P P F+ + DLL ML +P R+TA++AL H +
Sbjct: 636 KELKVWNMVEFPPVKPGQLRRIFKGEKLVNETGFDLLNGMLCLNPANRLTASEALQHDWF 695
Query: 302 SPYH---DPTDEPIAEAKFDWN 320
S + P D P+ AK + N
Sbjct: 696 SEHPKAVPPEDLPVYPAKSELN 717
>CE17321 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 360
Score = 137 bits (346), Expect = 2e-32
Identities = 92/295 (31%), Positives = 156/295 (52%), Gaps = 20/295 (6%)
Query: 22 YTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRH-EN 80
Y + +G G + V T + V +K I+KP V K+ RE+K+L++LR N
Sbjct: 38 YQLVRKLGRGKYSEVFEGFKMSTDEKVVVK-ILKP----VKKKKIKREIKILENLRGGTN 92
Query: 81 LICLEDIFLSPLE--DIYFVTELQGTDLHRLLQTRPLEKQFVQYFLYQILRGLKYVHSAG 138
+I L D+ P+ + +D +L QT L ++Y+LY++L+ L + HS G
Sbjct: 93 IITLLDVVKDPISRTPALIFEHVNNSDFKQLYQT--LSDYDIRYYLYELLKALDFCHSQG 150
Query: 139 VIHRDLKPSNILIN-ENCDLKICDFGLARIQDPQM--TGYVSTRYYRAPEIMLTWQKYNV 195
++HRD+KP N++I+ E +L++ D+GLA P+ V++RY++ PE+++ +Q Y+
Sbjct: 151 IMHRDVKPHNVMIDAEKRELRLIDWGLAEFYHPRQDYNVRVASRYFKGPELLVDYQCYDY 210
Query: 196 EVDIWSAGCIFAEMIEGK-PLFPGKDHVHQFSIITDLLGSP------PKDVIDTICSENT 248
+D+WS GC+ A MI K P F G D+ Q I +LG+ + ID N
Sbjct: 211 SLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTDELYEYIARYHIDLDPRFND 270
Query: 249 LKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPYLSP 303
+ S + + + P+A+D L+K+L +D +R+TA +A+ H Y P
Sbjct: 271 ILGRHSRKRWERFIHAENQHLVTPEALDFLDKLLRYDHAERLTAQEAMGHEYFRP 325
>7298142 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 722
Score = 137 bits (344), Expect = 4e-32
Identities = 95/308 (30%), Positives = 156/308 (49%), Gaps = 27/308 (8%)
Query: 18 ITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLR 77
I RY L +G G+FG V A D T+ VAIK I + + EL +L LR
Sbjct: 194 IAFRYEILEVIGKGSFGQVIRALDHKTNTHVAIKIIR---NKKRFLNQAVVELNILDELR 250
Query: 78 HENLICLEDIFLSPLEDIYF------VTELQGTDLHRLLQTRP---LEKQFVQYFLYQIL 128
++ ++ + L+ YF EL +L+ L++ ++ F I+
Sbjct: 251 EKDADGSHNV-IHMLDYTYFRKHLCITFELMSLNLYELIKKNNYNGFSMSLIRRFCNSIV 309
Query: 129 RGLKYVHSAGVIHRDLKPSNILINE--NCDLKICDFGLARIQDPQMTGYVSTRYYRAPEI 186
+ L+ ++ +IH DLKP NIL+ + + +K+ DFG + D ++ Y+ +R+YR+PE+
Sbjct: 310 KCLRLLYKENIIHCDLKPENILLKQRGSSSIKVIDFGSSCYVDRKIYTYIQSRFYRSPEV 369
Query: 187 MLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDT---- 242
+L Q Y +D+WS GCI AE+ G PLFPG++ V Q + I ++LG PPK +I
Sbjct: 370 ILGLQ-YGTAIDMWSLGCILAELYTGFPLFPGENEVEQLACIMEVLGLPPKVLISVARRR 428
Query: 243 ---ICSENTLKFVTSLPHRDPVPFSSRFQNL----EPDAIDLLEKMLVFDPKKRITAADA 295
S + + +T+ R P S ++ + ID L++ L +DP +R+T +A
Sbjct: 429 RLFFDSRDAPRCITNTKGRKRSPGSKSLAHILHCQDRYFIDFLQRCLEWDPAERMTPDEA 488
Query: 296 LAHPYLSP 303
H +L P
Sbjct: 489 AHHEFLQP 496
>CE23751 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 796
Score = 135 bits (339), Expect = 2e-31
Identities = 102/328 (31%), Positives = 164/328 (49%), Gaps = 54/328 (16%)
Query: 18 ITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYR----ELKLL 73
I RY L +G G+FG V A D Q VA+K + KR +R E+++L
Sbjct: 457 IAYRYEVLKVIGKGSFGQVIKAFDHKYQQYVALKLVRNE-------KRFHRQADEEIRIL 509
Query: 74 KHLRHE------NLICLEDIFLSPLEDIYFVT-ELQGTDLHRLLQTRPLEK---QFVQYF 123
HLR + N+I + D F + +T EL +L+ L++ + V+ F
Sbjct: 510 DHLRRQDSDGTHNIIHMLDYF--NFRNHKCITFELLSINLYELIKRNKFQGFSLMLVRKF 567
Query: 124 LYQILRGLKYVHSAGVIHRDLKPSNILINEN--CDLKICDFGLARIQDPQMTGYVSTRYY 181
Y +L L + +IH DLKP N+L+ + +K+ DFG + D ++ Y+ +R+Y
Sbjct: 568 AYSMLLCLDLLQKNRLIHCDLKPENVLLKQQGRSGIKVIDFGSSCFDDQRIYTYIQSRFY 627
Query: 182 RAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVID 241
RAPE++L KY + +D+WS GCI AE++ G PL PG+D Q ++I +LLG PP ++
Sbjct: 628 RAPEVILG-TKYGMPIDMWSLGCILAELLTGYPLLPGEDENDQLALIIELLGMPPPKSLE 686
Query: 242 T-------ICSENTLKF--VTSLPHRDPV------------------PFSSRFQNLEPDA 274
T I S+ ++ TS+P V +S+ +N+ +
Sbjct: 687 TAKRARTFITSKGYPRYCTATSMPDGSVVLAGARSKRGKMRGPPASRSWSTALKNMGDEL 746
Query: 275 -IDLLEKMLVFDPKKRITAADALAHPYL 301
+D L++ L +DP+ R+T A AL H +L
Sbjct: 747 FVDFLKRCLDWDPETRMTPAQALKHKWL 774
>CE19878 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 817
Score = 135 bits (339), Expect = 2e-31
Identities = 102/328 (31%), Positives = 164/328 (49%), Gaps = 54/328 (16%)
Query: 18 ITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYR----ELKLL 73
I RY L +G G+FG V A D Q VA+K + KR +R E+++L
Sbjct: 457 IAYRYEVLKVIGKGSFGQVIKAFDHKYQQYVALKLVRNE-------KRFHRQADEEIRIL 509
Query: 74 KHLRHE------NLICLEDIFLSPLEDIYFVT-ELQGTDLHRLLQTRPLEK---QFVQYF 123
HLR + N+I + D F + +T EL +L+ L++ + V+ F
Sbjct: 510 DHLRRQDSDGTHNIIHMLDYF--NFRNHKCITFELLSINLYELIKRNKFQGFSLMLVRKF 567
Query: 124 LYQILRGLKYVHSAGVIHRDLKPSNILINEN--CDLKICDFGLARIQDPQMTGYVSTRYY 181
Y +L L + +IH DLKP N+L+ + +K+ DFG + D ++ Y+ +R+Y
Sbjct: 568 AYSMLLCLDLLQKNRLIHCDLKPENVLLKQQGRSGIKVIDFGSSCFDDQRIYTYIQSRFY 627
Query: 182 RAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVID 241
RAPE++L KY + +D+WS GCI AE++ G PL PG+D Q ++I +LLG PP ++
Sbjct: 628 RAPEVILG-TKYGMPIDMWSLGCILAELLTGYPLLPGEDENDQLALIIELLGMPPPKSLE 686
Query: 242 T-------ICSENTLKF--VTSLPHRDPV------------------PFSSRFQNLEPDA 274
T I S+ ++ TS+P V +S+ +N+ +
Sbjct: 687 TAKRARTFITSKGYPRYCTATSMPDGSVVLAGARSKRGKMRGPPASRSWSTALKNMGDEL 746
Query: 275 -IDLLEKMLVFDPKKRITAADALAHPYL 301
+D L++ L +DP+ R+T A AL H +L
Sbjct: 747 FVDFLKRCLDWDPETRMTPAQALKHKWL 774
>CE05897 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 508
Score = 135 bits (339), Expect = 2e-31
Identities = 102/328 (31%), Positives = 164/328 (49%), Gaps = 54/328 (16%)
Query: 18 ITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYR----ELKLL 73
I RY L +G G+FG V A D Q VA+K + KR +R E+++L
Sbjct: 163 IAYRYEVLKVIGKGSFGQVIKAFDHKYQQYVALKLVRNE-------KRFHRQADEEIRIL 215
Query: 74 KHLRHE------NLICLEDIFLSPLEDIYFVT-ELQGTDLHRLLQTRPLEK---QFVQYF 123
HLR + N+I + D F + +T EL +L+ L++ + V+ F
Sbjct: 216 DHLRRQDSDGTHNIIHMLDYF--NFRNHKCITFELLSINLYELIKRNKFQGFSLMLVRKF 273
Query: 124 LYQILRGLKYVHSAGVIHRDLKPSNILINEN--CDLKICDFGLARIQDPQMTGYVSTRYY 181
Y +L L + +IH DLKP N+L+ + +K+ DFG + D ++ Y+ +R+Y
Sbjct: 274 AYSMLLCLDLLQKNRLIHCDLKPENVLLKQQGRSGIKVIDFGSSCFDDQRIYTYIQSRFY 333
Query: 182 RAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVID 241
RAPE++L KY + +D+WS GCI AE++ G PL PG+D Q ++I +LLG PP ++
Sbjct: 334 RAPEVILG-TKYGMPIDMWSLGCILAELLTGYPLLPGEDENDQLALIIELLGMPPPKSLE 392
Query: 242 T-------ICSENTLKF--VTSLPHRDPV------------------PFSSRFQNLEPDA 274
T I S+ ++ TS+P V +S+ +N+ +
Sbjct: 393 TAKRARTFITSKGYPRYCTATSMPDGSVVLAGARSKRGKMRGPPASRSWSTALKNMGDEL 452
Query: 275 -IDLLEKMLVFDPKKRITAADALAHPYL 301
+D L++ L +DP+ R+T A AL H +L
Sbjct: 453 FVDFLKRCLDWDPETRMTPAQALKHKWL 480
>Hs7106269 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 452
Score = 134 bits (337), Expect = 3e-31
Identities = 88/304 (28%), Positives = 146/304 (47%), Gaps = 31/304 (10%)
Query: 20 NRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHE 79
++Y L +G GA G+V A T + +A+KK+ + RE+K L+ +
Sbjct: 2 DQYCILGRIGEGAHGIVFKAKHVETGEIIALKKVALRRLEDGFPNQALREIKALQEMEDN 61
Query: 80 NLICLEDIFLSPLEDIYFVTELQGTDLHRLLQ--TRPLEKQFVQYFLYQILRGLKYVHSA 137
+ E +DL +++ RPL + V+ +L +L+G+ + H+
Sbjct: 62 QYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCHAN 121
Query: 138 GVIHRDLKPSNILINENCDLKICDFGLARIQDPQMTGYVSTRYYRAPEIMLTWQKYNVEV 197
++HRDLKP+N+LI+ + LKI DFGLAR+ P + + Y +V
Sbjct: 122 NIVHRDLKPANLLISASGQLKIADFGLARVFSPDGS-----------------RLYTHQV 164
Query: 198 DIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDV---IDTICSENTLKFVTS 254
S GCI E++ G PLFPGK+ + Q + +LG+P V + + N + F
Sbjct: 165 ATRSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYNKISFKEQ 224
Query: 255 LPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPYL----SPYHDPTDE 310
+ P+P ++ P A+DLL + L++ P +RI A+ AL H Y P H P++
Sbjct: 225 V----PMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQYFFTAPLPAH-PSEL 279
Query: 311 PIAE 314
PI +
Sbjct: 280 PIPQ 283
>Hs20550209 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 520
Score = 134 bits (337), Expect = 3e-31
Identities = 91/317 (28%), Positives = 157/317 (48%), Gaps = 29/317 (9%)
Query: 18 ITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLR 77
I RY L +G G+FG V D ++ VA+K I + ++ ELK+L+ LR
Sbjct: 100 IAYRYEVLETIGKGSFGQVAKCLDHKNNELVALKIIR---NKKRFHQQALMELKILEALR 156
Query: 78 HE------NLICLEDIFLSPLEDIYFVT-ELQGTDLHRLLQTRPLEK---QFVQYFLYQI 127
+ N++ ++D F + + +T EL G +L+ L++ + V+ F +
Sbjct: 157 KKDKDNTYNVVHMKDFFY--FRNHFCITFELLGINLYELMKNNNFQGFSLSIVRRFTLSV 214
Query: 128 LRGLKYVHSAGVIHRDLKPSNILINEN--CDLKICDFGLARIQDPQMTGYVSTRYYRAPE 185
L+ L+ + +IH DLKP NI++ + +K+ DFG + + ++ Y+ +R+YR+PE
Sbjct: 215 LKCLQMLSVEKIIHCDLKPENIVLYQKGQASVKVIDFGSSCYEHQKVYTYIQSRFYRSPE 274
Query: 186 IMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICS 245
++L Y+V +D+WS GCI AE+ G PLFPG++ V Q + I ++LG PP I T
Sbjct: 275 VILG-HPYDVAIDMWSLGCITAELYTGYPLFPGENEVEQLACIMEVLGLPPAGFIQTASR 333
Query: 246 ENTLKFVTSLP-----------HRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAAD 294
T P + D + + + +D L + LV++P R+T
Sbjct: 334 RQTFFDSKGFPKNITNNRGKKRYPDSKDLTMVLKTYDTSFLDFLRRCLVWEPSLRMTPDQ 393
Query: 295 ALAHPYLSPYHDPTDEP 311
AL H ++ + +P
Sbjct: 394 ALKHAWIHQSRNLKPQP 410
>SPAC23H4.17c [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 352
Score = 133 bits (335), Expect = 5e-31
Identities = 97/316 (30%), Positives = 159/316 (49%), Gaps = 35/316 (11%)
Query: 22 YTNLNPVGMGAFGLVCSATDTLTSQP--VAIKKIM---KPFSTSV----LAKRTYRELKL 72
Y + + G +G V A + ++ AIKK K S++ +++ RE+ L
Sbjct: 5 YKIIGFISSGTYGKVYKAVSSNSNDKRLFAIKKFKAESKQVSSNAQQTGVSQSAIREMML 64
Query: 73 LKHLRHENLICLEDIFLSP--LEDIYFVTE---LQGTDLHRLLQTRPLEKQFVQYFLYQI 127
+ ++HEN++ L + L + ++ E LQ H +TR + ++ L+QI
Sbjct: 65 CREIQHENIVSLVQVLLKDGTISMVFEYAEHDLLQIIHFHSRSRTRQIPPSILKSILWQI 124
Query: 128 LRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLAR-IQDPQMTGYVSTR-----YY 181
+ G+ Y+H ++HRDLKP+NI+I +KI D GL R I+DP + Y S R +Y
Sbjct: 125 INGVAYLHENWIMHRDLKPANIMITATGKVKIGDLGLGRLIRDPILPFYSSDRVVVTIWY 184
Query: 182 RAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKD-----------HVHQFSIITD 230
RAPE++L Y +D+W+ GCI+ EM+ PLF G + Q I +
Sbjct: 185 RAPELLLGAHDYTPAIDVWAIGCIYGEMLALSPLFKGDEIKMEDKKVVPFQSTQMLRIME 244
Query: 231 LLGSPPKDVIDTICSENTLKFVTSLPHR---DPVP-FSSRFQNLEPDAIDLLEKMLVFDP 286
LLG+P ++ + + ++S R + +P + +N +P +DLL KML +DP
Sbjct: 245 LLGTPTEERWPGLKNYPEYYQLSSFEVRYWNNLLPQWYQTVKNRDPQGLDLLMKMLQYDP 304
Query: 287 KKRITAADALAHPYLS 302
K RITA AL H + +
Sbjct: 305 KSRITAKQALEHVFFT 320
>7294866 [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 531
Score = 133 bits (335), Expect = 5e-31
Identities = 109/346 (31%), Positives = 170/346 (48%), Gaps = 44/346 (12%)
Query: 7 IRTQIFGTVFEITNRYTNLNPVGMGAFGLVCSAT--DTLTSQPVAIKKIMKPFSTSVLAK 64
++TQI T E Y VG G +G V A +T + A+K+I + L+
Sbjct: 84 MKTQIERTKVEDLFNYEGCK-VGRGTYGHVYKAKWKETSDGKEYALKQI----DGTGLSM 138
Query: 65 RTYRELKLLKHLRHENLICLEDIFLSPLE-DIYFVTELQGTDLHRLLQ----TRPLEKQ- 118
RE+ LL+ L+H+N+I L +FLS + ++ + + DL +++ + +KQ
Sbjct: 139 SACREIALLRELKHQNVITLIRVFLSHNDRKVFLLIDYAEHDLWHIIKFHRAAKATKKQV 198
Query: 119 -----FVQYFLYQILRGLKYVHSAGVIHRDLKPSNILI----NENCDLKICDFGLARIQD 169
V+ LYQIL G+ Y+HS V+HRDLKP+NIL+ NE +KI D G AR+ +
Sbjct: 199 VVPRGMVKSLLYQILDGIHYLHSNWVLHRDLKPANILVMGDGNERGRVKIADMGFARLFN 258
Query: 170 P------QMTGYVSTRYYRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKD--- 220
+ V T +YRAPE++L + Y +DIW+ GCIFAE++ +P+F +
Sbjct: 259 APLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDI 318
Query: 221 ------HVHQFSIITDLLGSPPK---DVIDTICSENTL--KFVTSLPHRDPVPFSSRFQN 269
H Q I +++G P + I + +TL F S +
Sbjct: 319 KTSNPYHHDQLDRIFNVMGFPQDKDWEDIKKMPEHHTLTKDFKRSTYSTCSLAKYMERHK 378
Query: 270 LEPD--AIDLLEKMLVFDPKKRITAADALAHPYLSPYHDPTDEPIA 313
++PD A LL+K+L+ DP KRIT+ A+ Y PT + A
Sbjct: 379 IKPDSKAFHLLQKLLLMDPNKRITSEQAMQDQYFQEEPQPTQDVFA 424
>Hs5922004 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 601
Score = 132 bits (333), Expect = 8e-31
Identities = 97/326 (29%), Positives = 160/326 (48%), Gaps = 50/326 (15%)
Query: 18 ITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLR 77
+ RY L +G G+FG V A D Q VA+K + + ++ E+++L+HLR
Sbjct: 218 VAYRYEVLKVIGKGSFGQVVKAYDHKVHQHVALKMVR---NEKRFHRQAAEEIRILEHLR 274
Query: 78 HE------NLICLEDIFLSPLEDIYFVTELQGTDLHRLLQTRPLEK---QFVQYFLYQIL 128
+ N+I + + F I EL +L+ L++ + V+ F + IL
Sbjct: 275 KQDKDNTMNVIHMLENFTFR-NHICMTFELLSMNLYELIKKNKFQGFSLPLVRKFAHSIL 333
Query: 129 RGLKYVHSAGVIHRDLKPSNILINEN--CDLKICDFGLARIQDPQMTGYVSTRYYRAPEI 186
+ L +H +IH DLKP NIL+ + +K+ DFG + + ++ Y+ +R+YRAPE+
Sbjct: 334 QCLDALHKNRIIHCDLKPENILLKQQGRSGIKVIDFGSSCYEHQRVYTYIQSRFYRAPEV 393
Query: 187 MLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSE 246
+L +Y + +D+WS GCI AE++ G PL PG+D Q + + +LLG P + ++D S+
Sbjct: 394 ILG-ARYGMPIDMWSLGCILAELLTGYPLLPGEDEGDQLACMIELLGMPSQKLLD--ASK 450
Query: 247 NTLKFVTSLPH--------------------------RDPVPFSSRFQNL-----EPDAI 275
FV+S + R P P S + N +P +
Sbjct: 451 RAKNFVSSKGYPRYCTVTTLSDGSVVLNGGRSRRGKLRGP-PESREWGNALKGCDDPLFL 509
Query: 276 DLLEKMLVFDPKKRITAADALAHPYL 301
D L++ L +DP R+T AL HP+L
Sbjct: 510 DFLKQCLEWDPAVRMTPGQALRHPWL 535
>Hs4503427 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 528
Score = 132 bits (333), Expect = 8e-31
Identities = 97/326 (29%), Positives = 160/326 (48%), Gaps = 50/326 (15%)
Query: 18 ITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLR 77
+ RY L +G G+FG V A D Q VA+K + + ++ E+++L+HLR
Sbjct: 145 VAYRYEVLKVIGKGSFGQVVKAYDHKVHQHVALKMVR---NEKRFHRQAAEEIRILEHLR 201
Query: 78 HE------NLICLEDIFLSPLEDIYFVTELQGTDLHRLLQTRPLEK---QFVQYFLYQIL 128
+ N+I + + F I EL +L+ L++ + V+ F + IL
Sbjct: 202 KQDKDNTMNVIHMLENFTFR-NHICMTFELLSMNLYELIKKNKFQGFSLPLVRKFAHSIL 260
Query: 129 RGLKYVHSAGVIHRDLKPSNILINEN--CDLKICDFGLARIQDPQMTGYVSTRYYRAPEI 186
+ L +H +IH DLKP NIL+ + +K+ DFG + + ++ Y+ +R+YRAPE+
Sbjct: 261 QCLDALHKNRIIHCDLKPENILLKQQGRSGIKVIDFGSSCYEHQRVYTYIQSRFYRAPEV 320
Query: 187 MLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSE 246
+L +Y + +D+WS GCI AE++ G PL PG+D Q + + +LLG P + ++D S+
Sbjct: 321 ILG-ARYGMPIDMWSLGCILAELLTGYPLLPGEDEGDQLACMIELLGMPSQKLLD--ASK 377
Query: 247 NTLKFVTSLPH--------------------------RDPVPFSSRFQNL-----EPDAI 275
FV+S + R P P S + N +P +
Sbjct: 378 RAKNFVSSKGYPRYCTVTTLSDGSVVLNGGRSRRGKLRGP-PESREWGNALKGCDDPLFL 436
Query: 276 DLLEKMLVFDPKKRITAADALAHPYL 301
D L++ L +DP R+T AL HP+L
Sbjct: 437 DFLKQCLEWDPAVRMTPGQALRHPWL 462
>At2g23070 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 432
Score = 132 bits (331), Expect = 1e-30
Identities = 96/303 (31%), Positives = 163/303 (53%), Gaps = 28/303 (9%)
Query: 18 ITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHL- 76
+ + Y + VG G + V ++ IK I+KP V K+ RE+K+L++L
Sbjct: 128 VQDDYEVVRKVGRGKYSEVFEGIHATDNEKCVIK-ILKP----VKKKKIKREIKILQNLC 182
Query: 77 RHENLICLEDIFL---SPLEDIYFVTELQGTDLHRLLQTRPLEKQFVQYFLYQILRGLKY 133
N++ L DI S + F + D L T L V+Y+++++L+ L +
Sbjct: 183 GGPNIVKLLDIVRDQQSKTPSLIF-EHVNNKDFKVLYPT--LSDYDVRYYIFELLKALDF 239
Query: 134 VHSAGVIHRDLKPSNILIN-ENCDLKICDFGLARIQDP--QMTGYVSTRYYRAPEIMLTW 190
HS G++HRD+KP N++I+ E L++ D+GLA P + V++RY++ PE+++
Sbjct: 240 CHSRGIMHRDVKPHNVMIDHEQRKLRLIDWGLAEFYHPGKEYNVRVASRYFKGPELLVDL 299
Query: 191 QKYNVEVDIWSAGCIFAEMIEGK-PLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTL 249
Q Y+ +D+WS GC+FA MI K P F G D+ Q I +LG+ D ++ ++ +
Sbjct: 300 QDYDYSLDLWSLGCMFAGMIFRKEPFFYGHDNYDQLVKIAKVLGT---DELNAYLNKYRI 356
Query: 250 KF---VTSLPHRDPVPFSSRFQNLE------PDAIDLLEKMLVFDPKKRITAADALAHPY 300
+ +TSL R ++F N E P+A+D ++K+L +D ++R TA +A+AHPY
Sbjct: 357 ELDPNLTSLVGRHSRKPWTKFINSENQHLAVPEAVDFVDKLLRYDHQERPTAKEAMAHPY 416
Query: 301 LSP 303
P
Sbjct: 417 FYP 419
>Hs4503429 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 553
Score = 131 bits (330), Expect = 2e-30
Identities = 97/323 (30%), Positives = 157/323 (48%), Gaps = 48/323 (14%)
Query: 21 RYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHLRHE- 79
RY L +G G+FG V D Q VA+K + + ++ E+++L+HL+ +
Sbjct: 173 RYEVLKIIGKGSFGQVARVYDHKLRQYVALKMVR---NEKRFHRQAAEEIRILEHLKKQD 229
Query: 80 -----NLICLEDIFLSPLEDIYFVTELQGTDLHRLLQTRPLEK---QFVQYFLYQILRGL 131
N+I + + F + EL DL+ L++ + Q V+ F IL+ L
Sbjct: 230 KTGSMNVIHMLESFTFR-NHVCMAFELLSIDLYELIKKNKFQGFSVQLVRKFAQSILQSL 288
Query: 132 KYVHSAGVIHRDLKPSNILINEN--CDLKICDFGLARIQDPQMTGYVSTRYYRAPEIMLT 189
+H +IH DLKP NIL+ + K+ DFG + + ++ Y+ +R+YRAPEI+L
Sbjct: 289 DALHKNKIIHCDLKPENILLKHHGRSSTKVIDFGSSCFEYQKLYTYIQSRFYRAPEIILG 348
Query: 190 WQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTL 249
+Y+ +DIWS CI AE++ G+PLFPG+D Q + + +LLG PP +++ S+
Sbjct: 349 -SRYSTPIDIWSFRCILAELLTGQPLFPGEDEGDQLACMMELLGMPPPKLLEQ--SKRAK 405
Query: 250 KFVTS--LPHRDPVPF------------SSRFQNLEPDA----------------IDLLE 279
F+ S +P V S R + P I+ L+
Sbjct: 406 YFINSKGIPRYCSVTTQADGRVVLVGGRSRRGKKRGPPGSKDWGTALKGCDDYLFIEFLK 465
Query: 280 KMLVFDPKKRITAADALAHPYLS 302
+ L +DP R+T A AL HP++S
Sbjct: 466 RCLHWDPSARLTPAQALRHPWIS 488
>At3g50000 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 333
Score = 131 bits (329), Expect = 2e-30
Identities = 97/299 (32%), Positives = 162/299 (53%), Gaps = 30/299 (10%)
Query: 22 YTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHL-RHEN 80
Y + VG G + V + + + I KI+KP V K+ RE+K+L++L N
Sbjct: 34 YEVVRKVGRGKYSEVFEGIN-MNNNEKCIIKILKP----VKKKKIRREIKILQNLCGGPN 88
Query: 81 LICLEDIFL---SPLEDIYFVTELQGTDLHRLLQTRPLEKQFVQYFLYQILRGLKYVHSA 137
++ L D+ S + F + TD L T L ++Y++Y++L+ L + HS
Sbjct: 89 IVKLLDVVRDQHSKTPSLIF-EYVNSTDFKVLYPT--LTDYDIRYYIYELLKALDFCHSQ 145
Query: 138 GVIHRDLKPSNILI-NENCDLKICDFGLARIQDP--QMTGYVSTRYYRAPEIMLTWQKYN 194
G++HRD+KP N++I +E L++ D+GLA P + V++RY++ PE+++ Q Y+
Sbjct: 146 GIMHRDVKPHNVMIDHELRKLRLIDWGLAEFYHPGKEYNVRVASRYFKGPELLVDLQDYD 205
Query: 195 VEVDIWSAGCIFAEMIEGK-PLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLKFVT 253
+D+WS GC+FA MI K P F G D+ Q I +LG+ D ++ ++ L+ T
Sbjct: 206 YSLDMWSLGCMFAGMIFRKEPFFYGHDNQDQLVKIAKVLGT---DELNAYLNKYQLELDT 262
Query: 254 SLP----HRDPVPFSSRFQN------LEPDAIDLLEKMLVFDPKKRITAADALAHPYLS 302
L P+ S+F N + P+AID L+K+L +D + R+TA +A+AHPY +
Sbjct: 263 QLEALVGRHSRKPW-SKFINADNRHLVSPEAIDYLDKLLRYDHQDRLTAKEAMAHPYFA 320
>SPAC1D4.11c [T] KOG0671 LAMMER dual specificity kinases
Length = 690
Score = 130 bits (328), Expect = 3e-30
Identities = 94/329 (28%), Positives = 153/329 (45%), Gaps = 45/329 (13%)
Query: 17 EITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIK---KIMKPFSTSVLAKRTYRELKLL 73
+ NRYT + +G G FG V D T + AIK I K S++ R + +
Sbjct: 357 KFANRYTVVRLLGHGTFGKVIQCYDQSTGRHCAIKVTRAIPKYREASLIELRVLQTIAHS 416
Query: 74 KHLRHENLICLEDIFLSPLEDIYFVTELQGTDLHRLLQTR---PLEKQFVQYFLYQILRG 130
I L D F + I VT+L G + L+ P + +Q Q+ +
Sbjct: 417 DPTNENKCIQLRDYF-DYRKHICIVTDLFGWSVFDFLKNNNYIPFPLKHIQMLSQQLFKS 475
Query: 131 LKYVHSAGVIHRDLKPSNILINEN-------------------CDLKICDFGLARIQDPQ 171
+ ++HS G++H DLKP N+L+ N C++++ DFG A +D
Sbjct: 476 VAFLHSLGLVHTDLKPENVLLVSNASRTIRLPYRNYSQKVLNSCEIRLIDFGSATFEDEY 535
Query: 172 MTGYVSTRYYRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDL 231
+ VSTR+YRAPEI+L ++ D+WS GCI E+ G+ LF + ++ +
Sbjct: 536 HSSVVSTRHYRAPEIIL-GLGWSYPCDVWSIGCILVELFTGQALFQTHEDSEHLCMMEKI 594
Query: 232 LGSPPKDVIDT--------ICSENTLKFVTSLPHRDPVPFSSRFQNLE-------PDA-- 274
LG +++I S+ +++ S + + + Q LE P+
Sbjct: 595 LGPFDRNMISRSSRTSQRFFKSDGKVRYPLSNTPKKSINYLQSLQTLEQIFAVSSPEVAL 654
Query: 275 -IDLLEKMLVFDPKKRITAADALAHPYLS 302
+DLL+K+ V+DPK+RITA +AL HP+ +
Sbjct: 655 LLDLLKKVFVYDPKRRITAKEALWHPFFT 683
>Hs17452757 [UT] KOG0662 Cyclin-dependent kinase CDK5
Length = 366
Score = 130 bits (326), Expect = 5e-30
Identities = 95/302 (31%), Positives = 149/302 (48%), Gaps = 17/302 (5%)
Query: 9 TQIFGTVFEITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYR 68
T + + + L +G G +G V A + T + VA+K + + + R
Sbjct: 62 TVLASNILSREDEQKKLEKIGEGTYGTVFKAKNWETHEIVALKWVRLDDNDDGVPSSALR 121
Query: 69 ELKLLKHLRHENLICLEDIFLSPLEDIYFVTELQGTDLHRLLQT--RPLEKQFVQYFLYQ 126
E+ LLK L+H+N++ L D+ S + + V + L + + L+ + V+ FL+Q
Sbjct: 122 EICLLKELKHKNIVRLHDLLHSD-KKLTLVFKFCHQHLKKYFDSCNGDLDPEIVKSFLFQ 180
Query: 127 ILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQMTGYVSTRYYRAPEI 186
+L+GL + HS V+ RDLKP N+LIN N +LK+ DFGL+R + YV ++ A
Sbjct: 181 LLKGLGFCHSRNVLRRDLKPQNLLINRNGELKLADFGLSRAFGIPIC-YV---FFGA--- 233
Query: 187 MLTWQKYNVEVDIWSAGCIFAEMIE-GKPLFPGKDHVHQFSIITDLLGSPPKDVIDTICS 245
+ Y+ +D+WSAGCIFAE+ G PLFPG D Q I LLG K+ ++
Sbjct: 234 ----KLYSTSIDLWSAGCIFAELANAGWPLFPGNDVDDQLKRIFWLLGMLTKEQWPSMTK 289
Query: 246 ENTLKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPYLSPYH 305
K P + L DLL+ +L +P + I+A +AL +PY S +
Sbjct: 290 LPDYKLYPLYP--ATTSLVNIVPKLSATGRDLLQNLLKCNPCQCISAEEALQYPYFSDFC 347
Query: 306 DP 307
P
Sbjct: 348 PP 349
>CE05686 [A] KOG0670 U4/U6-associated splicing factor PRP4
Length = 775
Score = 129 bits (323), Expect = 1e-29
Identities = 99/338 (29%), Positives = 151/338 (44%), Gaps = 70/338 (20%)
Query: 18 ITNRYTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHL- 76
+ RY + G G FG VC D VA+K I + V+ K REL++L+ L
Sbjct: 451 LDTRYRVVGFTGAGVFGNVCRCNDQTKGNTVAVKIIR---NNEVMYKTGLRELEVLRKLN 507
Query: 77 -----------------RHENLICLEDIFLSPLEDIYFVTELQGTDLHRLL----QTRPL 115
+H N +CL V E +L LL Q L
Sbjct: 508 EADKEDKYHCLRLFRTFKHHNHLCL-------------VFENLSMNLRELLKKYGQKDGL 554
Query: 116 EKQFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILINEN-CDLKICDFGLA-RIQDPQMT 173
+ V+ + Q+L L+ + +H D+KP NIL+NE+ LK+CDFG A R+ + ++
Sbjct: 555 HLKAVRSYAQQLLLALRLLKKLEFVHADIKPDNILVNESKLTLKLCDFGSAGRVNEQELA 614
Query: 174 GYVSTRYYRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLG 233
Y+ +R+YRAPEIML +++ +D+WS E+ GK +FPG+ + H + TD+ G
Sbjct: 615 PYLVSRFYRAPEIMLG-VRHDYAIDLWSVAVTLYEVYTGKIMFPGRTNNHMLKLFTDVKG 673
Query: 234 SPPKDV---------------------IDTICSENTLKFVTSL-PHRDPVPFSSRFQNLE 271
P + +D + N + + +L P RD Q L
Sbjct: 674 KYPNKLVRKSQFKDTHFDVNCNLLYQEVDKVTERNKITVLANLKPTRDLESELIAGQRLS 733
Query: 272 PDAID-------LLEKMLVFDPKKRITAADALAHPYLS 302
D +D LL+ ML+ DP KR T +AL HP+ +
Sbjct: 734 RDQMDQIQAFRTLLDGMLILDPSKRTTCNEALKHPFFT 771
>YPL042c [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 555
Score = 128 bits (322), Expect = 1e-29
Identities = 95/312 (30%), Positives = 158/312 (50%), Gaps = 36/312 (11%)
Query: 38 SATDTLTSQPVAIKKIMKPFSTSV----------LAKRTYRELKLLKHLRHENLICLEDI 87
S TL +P+ + +K F T +++ RE+ L + L +++L L +I
Sbjct: 166 SQKQTLIKKPLTVFYAIKKFKTEKDGVEQLHYTGISQSACREMALCRELHNKHLTTLVEI 225
Query: 88 FLSPLEDIYFVTELQGTDLHRLL------QTRPLEKQFVQYFLYQILRGLKYVHSAGVIH 141
FL + ++ V E DL +++ + R + + V+ ++Q+L G+ Y+H V+H
Sbjct: 226 FLER-KCVHMVYEYAEHDLLQIIHFHSHPEKRMIPPRMVRSIMWQLLDGVSYLHQNWVLH 284
Query: 142 RDLKPSNILINENCDLKICDFGLAR----IQDPQMTG--YVSTRYYRAPEIMLTWQKYNV 195
RDLKP+NI++ + +KI D GLAR + TG V T +YRAPE++L + Y
Sbjct: 285 RDLKPANIMVTIDGCVKIGDLGLARKFHNMLQTLYTGDKVVVTIWYRAPELLLGARHYTP 344
Query: 196 EVDIWSAGCIFAEMIEGKPLFPGKD-----------HVHQFSIITDLLGSPPKDVIDTIC 244
VD+WS GCIFAE+I +P+F G++ V+Q I ++LG+P + + +
Sbjct: 345 AVDLWSVGCIFAELIGLQPIFKGEEAKLDSKKTVPFQVNQLQRILEVLGTPDQKIWPYLE 404
Query: 245 SENTLKFVTSLP-HRDPV-PFSSRFQNLEPDAIDLLEKMLVFDPKKRITAADALAHPYLS 302
+T P +RD + + + A+ LL +L +DP KRI A +AL H Y +
Sbjct: 405 KYPEYDQITKFPKYRDNLATWYHSAGGRDKHALSLLYHLLNYDPIKRIDAFNALEHKYFT 464
Query: 303 PYHDPTDEPIAE 314
P E + E
Sbjct: 465 ESDIPVSENVFE 476
>At5g67380 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 333
Score = 128 bits (322), Expect = 1e-29
Identities = 96/298 (32%), Positives = 162/298 (54%), Gaps = 28/298 (9%)
Query: 22 YTNLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYRELKLLKHL-RHEN 80
Y + VG G + V + + S+ I KI+KP V K+ RE+K+L++L N
Sbjct: 34 YEVVRKVGRGKYSEVFEGIN-VNSKEKCIIKILKP----VKKKKIRREIKILQNLCGGPN 88
Query: 81 LICLEDIFL---SPLEDIYFVTELQGTDLHRLLQTRPLEKQFVQYFLYQILRGLKYVHSA 137
++ L D+ S + F + TD L T L ++Y++Y++L+ L + HS
Sbjct: 89 IVKLLDVVRDQHSKTPSLIF-EYVNSTDFKVLYPT--LTDYDIRYYIYELLKALDFCHSQ 145
Query: 138 GVIHRDLKPSNILI-NENCDLKICDFGLARIQDP--QMTGYVSTRYYRAPEIMLTWQKYN 194
G++HRD+KP N++I +E L++ D+GLA P + V++RY++ PE+++ Q Y+
Sbjct: 146 GIMHRDVKPHNVMIDHELRKLRLIDWGLAEFYHPGKEYNVRVASRYFKGPELLVDLQDYD 205
Query: 195 VEVDIWSAGCIFAEMIEGK-PLFPGKDHVHQFSIITDLLGSPPKDVIDTICSENTLKF-- 251
+D+WS GC+FA MI K P F G D+ Q I +LG+ D ++ ++ L+
Sbjct: 206 YSLDMWSLGCMFAGMIFRKEPFFYGHDNQDQLVKIAKVLGT---DELNAYLNKYQLELDP 262
Query: 252 -VTSLPHRDPVPFSSRFQN------LEPDAIDLLEKMLVFDPKKRITAADALAHPYLS 302
+ +L R S+F N + P+AID L+K+L +D + R+TA +A+AH Y +
Sbjct: 263 QLEALVGRHSRKPWSKFINADNQHLVSPEAIDFLDKLLRYDHQDRLTAKEAMAHAYFA 320
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.321 0.139 0.421
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,717,593
Number of Sequences: 60738
Number of extensions: 1107810
Number of successful extensions: 7590
Number of sequences better than 1.0e-05: 1669
Number of HSP's better than 0.0 without gapping: 557
Number of HSP's successfully gapped in prelim test: 1112
Number of HSP's that attempted gapping in prelim test: 3790
Number of HSP's gapped (non-prelim): 2139
length of query: 444
length of database: 30,389,216
effective HSP length: 110
effective length of query: 334
effective length of database: 23,708,036
effective search space: 7918484024
effective search space used: 7918484024
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)