ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI5418 good S KOG3969 Function unknown Uncharacterized conserved protein
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI5418 1885395 1884346 -350
(350 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YLR270w [S] KOG3969 Uncharacterized conserved protein 493 e-139
YOR173w [S] KOG3969 Uncharacterized conserved protein 427 e-120
SPBP4H10.20 [S] KOG3969 Uncharacterized conserved protein 233 3e-61
7296680 [S] KOG3969 Uncharacterized conserved protein 193 3e-49
Hs7661734 [S] KOG3969 Uncharacterized conserved protein 178 1e-44
CE23280 [S] KOG3969 Uncharacterized conserved protein 150 2e-36
ECU10g1710 [S] KOG3969 Uncharacterized conserved protein 86 8e-17
>YLR270w [S] KOG3969 Uncharacterized conserved protein
Length = 350
Score = 493 bits (1269), Expect = e-139
Identities = 225/344 (65%), Positives = 286/344 (82%), Gaps = 3/344 (0%)
Query: 10 DFRALIDEFRFSRVLNSNPQTKQISLLGTIKGQDAIVTLEKTHFQFDKVVNNPNS---ST 66
DF +LI F+F VL+SNPQTK +SLLGTI +DAI+T EKTHF FD+ V P+ ST
Sbjct: 7 DFASLIKRFQFVSVLDSNPQTKVMSLLGTIDNKDAIITAEKTHFLFDETVRRPSQDGRST 66
Query: 67 LSLHQCESEYSCMNSIQTLKPIANNDIYFWGMSVMKQDLELNPTAKINLIWPATQVHIEK 126
L+ CE+EYSC+N IQ LK I +NDIY+WG+SV+KQD+E NPTAK+NLIWPAT +HI+K
Sbjct: 67 PVLYNCENEYSCINGIQELKEITSNDIYYWGLSVIKQDMESNPTAKLNLIWPATPIHIKK 126
Query: 127 YDKQLCHMVRETPEIYKRIVKPYVDDMVNNGRLQWVQNILYNGAESDRVVFKYFDQESPK 186
Y++Q H+VRETPE+YKRIV+PY+++M NNGRL+WV NILY GAES+RVV+K F +E+
Sbjct: 127 YEQQNFHLVRETPEMYKRIVQPYIEEMCNNGRLKWVNNILYEGAESERVVYKDFSEENKD 186
Query: 187 DGFVVLPDMKWDGVNMDALYLVAIVHRDDIKSLRDLRPEHQQWLIDMKNKIRSVVPSCYN 246
DGF++LPDMKWDG+N+D+LYLVAIV+R DIK++RDLR +QWLI++ NKIRS+VP CYN
Sbjct: 187 DGFLILPDMKWDGMNLDSLYLVAIVYRTDIKTIRDLRYSDRQWLINLNNKIRSIVPGCYN 246
Query: 247 YLVPADQLRLFIHYQPSYYHFHIHIVNVRHSGLGDGIAVGKAHLIEDVIENLNYMGPEGY 306
Y V D+LR+ +HYQPSYYHFHIHIVN++H GLG+ IA GKA L+ED+IE LNY+GPEGY
Sbjct: 247 YAVHPDELRILVHYQPSYYHFHIHIVNIKHPGLGNSIAAGKAILLEDIIEMLNYLGPEGY 306
Query: 307 MNRTMTYVIGENHHLWKNGLEQELEQQLKDDGIPEPPEITNDFE 350
MN+T+TY IGENH LWK GLE+EL +QL+ DGIP+ P+I N F+
Sbjct: 307 MNKTITYAIGENHDLWKRGLEEELTKQLERDGIPKIPKIVNGFK 350
>YOR173w [S] KOG3969 Uncharacterized conserved protein
Length = 397
Score = 427 bits (1099), Expect = e-120
Identities = 197/344 (57%), Positives = 261/344 (75%), Gaps = 4/344 (1%)
Query: 10 DFRALIDEFRFSRVLNSNPQTKQISLLGTIKGQDAIVTLEKTHFQFDKVVNNPNSSTLS- 68
D +LI F++ RVL+SNP TK ISLLG+I G+DA++T EKTHF FD+ V P+ S S
Sbjct: 49 DLASLIGRFKYVRVLDSNPHTKVISLLGSIDGKDAVLTAEKTHFIFDETVRRPSQSGRST 108
Query: 69 ---LHQCESEYSCMNSIQTLKPIANNDIYFWGMSVMKQDLELNPTAKINLIWPATQVHIE 125
H+ EYS +N I LK + +NDIY+WG+SV+KQ + NPTAK+NLIWPA+Q HI+
Sbjct: 109 PIFFHREIDEYSFLNGITDLKELTSNDIYYWGLSVLKQHILHNPTAKVNLIWPASQFHIK 168
Query: 126 KYDKQLCHMVRETPEIYKRIVKPYVDDMVNNGRLQWVQNILYNGAESDRVVFKYFDQESP 185
YD+Q H+VRETP++Y+ IV P++ +M + R++WV NILY GAE DRVV+K + +
Sbjct: 169 GYDQQDLHVVRETPDMYRNIVVPFIQEMCTSERMKWVNNILYEGAEDDRVVYKEYSSRNK 228
Query: 186 KDGFVVLPDMKWDGVNMDALYLVAIVHRDDIKSLRDLRPEHQQWLIDMKNKIRSVVPSCY 245
+DGFV+LPDMKWDG+N+D+LYLVAIV+RDDIKSLRDL P H+ WLI + KI++++P Y
Sbjct: 229 EDGFVILPDMKWDGINIDSLYLVAIVYRDDIKSLRDLNPNHRDWLIRLNKKIKTIIPQHY 288
Query: 246 NYLVPADQLRLFIHYQPSYYHFHIHIVNVRHSGLGDGIAVGKAHLIEDVIENLNYMGPEG 305
+Y V D+LR+FIHYQPSYYHFH+HIVN+RH G+G+ G L+EDVIE L ++GPEG
Sbjct: 289 DYNVNPDELRVFIHYQPSYYHFHVHIVNIRHPGVGEERGSGMTILLEDVIEALGFLGPEG 348
Query: 306 YMNRTMTYVIGENHHLWKNGLEQELEQQLKDDGIPEPPEITNDF 349
YM +T+TYVIGENH LWK G ++E+E+QLK DGI PE + F
Sbjct: 349 YMKKTLTYVIGENHDLWKKGFKEEVEKQLKHDGIATSPEKGSGF 392
>SPBP4H10.20 [S] KOG3969 Uncharacterized conserved protein
Length = 304
Score = 233 bits (594), Expect = 3e-61
Identities = 124/310 (40%), Positives = 192/310 (61%), Gaps = 23/310 (7%)
Query: 14 LIDEFRFSRVLNSNPQTKQISLLGTIKGQDAIVTLEKTHFQFDKVVNNPNSSTLSLHQCE 73
L+ EF+F ++L + ++K I+L G I+ + A++ LEKT F + T+ L Q
Sbjct: 11 LLKEFKFEKILKDDTKSKIITLYGKIRNEVALLLLEKTAFDLN---------TIKLDQLA 61
Query: 74 SEYSCMNSIQTLKPIANNDIYFWGMSVMKQDLELNPTAKINLIWPATQVHIEKYDKQLCH 133
+ +Q K + NND++ W +S QD P+ K LIWPA++ H+ KY Q
Sbjct: 62 T------FLQDTKLVENNDVFHWFLSTNFQDCSTLPSVKSTLIWPASETHVRKYSSQKKR 115
Query: 134 MVRETPEIYKRIVKPYVDDMVNNGRLQWVQNILYNGAESDRVVFKYFDQESPKDGFVVLP 193
MV ETPE+Y ++ KP+++ ++QWV+NIL + AE++R+V + P +GF+V+P
Sbjct: 116 MVCETPEMYLKVTKPFIETQ-RGPQIQWVENILTHKAEAERIV---VEDPDPLNGFIVIP 171
Query: 194 DMKWDGVNMDALYLVAIVHRDDIKSLRDLRPEHQQWLIDMKNKIRSVVPSCYNYLVPADQ 253
D+KWD M AL L+AIVH DI S+RDL+ +H L +++NK+ + VP + V +Q
Sbjct: 172 DLKWDRQTMSALNLMAIVHATDIASIRDLKYKHIPLLENIRNKVLTEVPK--QFSVDKNQ 229
Query: 254 LRLFIHYQPSYYHFHIHIVNVRHSGLGDGIAVGKAHLIEDVIENLNYMGPEGYMNRTMTY 313
L++F+HY PSYYH H+HI++V H GDG AVG+A L++DVI+ L P+G N +T+
Sbjct: 230 LKMFVHYLPSYYHLHVHILHVDHE-TGDGSAVGRAILLDDVIDRLR-NSPDGLENVNITF 287
Query: 314 VIGENHHLWK 323
IGE H L++
Sbjct: 288 NIGEQHFLFQ 297
>7296680 [S] KOG3969 Uncharacterized conserved protein
Length = 374
Score = 193 bits (491), Expect = 3e-49
Identities = 119/319 (37%), Positives = 180/319 (56%), Gaps = 23/319 (7%)
Query: 15 IDEFRFSRVLNSNPQTKQISLLGTIKG---QDAIVTLEKTHFQFDKVVNNPNSSTLSLHQ 71
+ +F+ R+L +N K ISLLGT DAIV EK ++ V +T S +
Sbjct: 17 LSKFQLKRILTNNSVRKSISLLGTFPDLGTDDAIVVFEKNAYRESDV------ATASSEE 70
Query: 72 CESEYSCMNSIQTLKPIANNDIYFWGMSVMKQDLELNPTAKINLIWPATQVHIEKYDKQL 131
+ S + + N+IY V QDL + K +I+PAT+ HIEKY
Sbjct: 71 SPKKPSYFTADLKVDTEFINNIYGSFQVVPTQDL---CSVKSTVIYPATEKHIEKYSVSQ 127
Query: 132 CHMVRETPEIYKRIVKPYVDDMVNNGRLQWVQNILYNGAESDRVVFKYFDQESPKDGFVV 191
+++RETP++Y+RI PY+ + L+WV NIL + E++R+V+ + PK GF++
Sbjct: 128 KYLIRETPDLYQRITLPYLTS--SQFSLEWVYNILEHKQETERIVY---EDRDPKTGFIL 182
Query: 192 LPDMKWDGVNMDALYLVAIVHRDDIKSLRDLRPEHQQWLIDMKNKIRSVVPSCYNYLVPA 251
LPD+KWDG N++ LYL+ IVH+ DIKSLRDL H L +++ + + Y +
Sbjct: 183 LPDLKWDGRNVETLYLLGIVHKRDIKSLRDLNESHLDLLRNVRQASKDAIAKLYG--INP 240
Query: 252 DQLRLFIHYQPSYYHFHIHIVNVRHSGLGDGIAVGKAHLIEDVIENLNYMGPEGYMNRTM 311
+QLR++ HYQPS+YH H+HI VR+ GI K+H+++ VI NL M P+ Y T+
Sbjct: 241 NQLRMYFHYQPSFYHLHVHINPVRND--APGIWCEKSHMLDTVINNLELM-PDYYQRATL 297
Query: 312 TYVIGENHHLWKNGLEQEL 330
+V+ E + L + EQEL
Sbjct: 298 PFVLYEGNKL-LDLYEQEL 315
>Hs7661734 [S] KOG3969 Uncharacterized conserved protein
Length = 337
Score = 178 bits (451), Expect = 1e-44
Identities = 116/323 (35%), Positives = 172/323 (52%), Gaps = 41/323 (12%)
Query: 18 FRFSRVLNSNPQTKQISLLGTIK-------GQDAIVTLEKTHFQFDKVVNN-PNSSTLSL 69
FR +VL + + K I L G + G+DA+V LEKT FQ ++V S L L
Sbjct: 47 FRLQKVLRESARDKIIFLHGKVNEASGDGDGEDAVVILEKTPFQVEQVAQLLTGSPELQL 106
Query: 70 HQCESEYSCMNSIQTLKPIANNDIYFWGMSVMKQDLELNPTAKINLIWPATQVHIEKYDK 129
YS + P ND+ K +++PAT+ H++KY +
Sbjct: 107 QFSNDIYS---TYHLFPPRQLNDV------------------KTTVVYPATEKHLQKYLR 145
Query: 130 QLCHMVRETPEIYKRIVKPYVDDMVNNGRLQWVQNILYNGAESDRVVFKYFDQESPKDGF 189
Q ++RET + Y+ I P+++ + +QWV NIL AE+DR+VF+ D P DGF
Sbjct: 146 QDLRLIRETGDDYRNITLPHLESQSLS--IQWVYNILDKKAEADRIVFENPD---PSDGF 200
Query: 190 VVLPDMKWDGVNMDALYLVAIVHRDDIKSLRDLRPEHQQWLIDMKNKIRSVVPSCYNYLV 249
V++PD+KW+ +D LYL+AI HR I+SLRDL PEH L ++ ++ + + Y +
Sbjct: 201 VLIPDLKWNQQQLDDLYLIAICHRRGIRSLRDLTPEHLPLLRNILHQGQEAI--LQRYRM 258
Query: 250 PADQLRLFIHYQPSYYHFHIHIVNVRHSGLGDGIAVGKAHLIEDVIENLNYMGPEGYMNR 309
D LR+++HY PSYYH H+H + G G V +AHL+ +VIENL P Y R
Sbjct: 259 KGDHLRVYLHYLPSYYHLHVHFTALGFEAPGSG--VERAHLLAEVIENLE-CDPRHYQQR 315
Query: 310 TMTYVIGENHHLWKNGLEQELEQ 332
T+T+ + + L K L QE +Q
Sbjct: 316 TLTFALRADDPLLK--LLQEAQQ 336
>CE23280 [S] KOG3969 Uncharacterized conserved protein
Length = 311
Score = 150 bits (380), Expect = 2e-36
Identities = 95/300 (31%), Positives = 159/300 (52%), Gaps = 30/300 (10%)
Query: 15 IDEFRFSRVLNSNPQTKQIS-LLGTIKGQDAIVTLEKTHFQFDKVVNNPNSSTLSLHQCE 73
+ + +F +L ++ K + LL G I+ K+ F +K
Sbjct: 23 LQDAKFQEILGADSSHKSLFVLLSHPDGSQGILLANKSPFSEEK---------------- 66
Query: 74 SEYSCMNSIQTLKPIANNDIYFWGMSVMKQDLELNPTAKINLIWPATQVHIEKYDKQLCH 133
S+ + + L+ I+ NDI+ G ++ D +LN K LI+P I KY ++
Sbjct: 67 SDIEKLLATAQLQEISRNDIF--GSYNIEIDPKLN-LLKSQLIYPINDRLIAKYRQEEKF 123
Query: 134 MVRETPEIYKRIVKPYVDDMVNNGRLQWVQNILYNGAESDRVVFKYFDQESPKDGFVVLP 193
++RETPE+Y+ + +PY++ N L WV N L +E D++VF+ D E+ GFV+L
Sbjct: 124 VIRETPELYETVTRPYIEKYQLN--LNWVYNCLEKRSEVDKIVFEDPDNEN---GFVLLQ 178
Query: 194 DMKWDGVNMDALYLVAIVHRDDIKSLRDLRPEHQQWLIDMKNKIRSVVPSCYNYLVPADQ 253
D+KWDG ++ LY++AI HR +KS+RDL + + L +M++K + Y + DQ
Sbjct: 179 DIKWDGKTLENLYVLAICHRHGLKSVRDLTGDDLEMLYNMRDKSLEAINQKYG--LKTDQ 236
Query: 254 LRLFIHYQPSYYHFHIHIVNVRHSGLGDGIAVGKAHLIEDVIENLNYMGPEGYMNRTMTY 313
++ + HYQPS+YH H+H +N+++ A L++DVI NL + PE Y T+T+
Sbjct: 237 IKCYFHYQPSFYHLHVHFINLKYD--APASTTMSAILLDDVINNLE-LNPEHYKKSTLTF 293
>ECU10g1710 [S] KOG3969 Uncharacterized conserved protein
Length = 263
Score = 85.9 bits (211), Expect = 8e-17
Identities = 54/209 (25%), Positives = 110/209 (51%), Gaps = 22/209 (10%)
Query: 90 NNDIYFWGMSVMKQDLELNPTAKINLIWPATQVHIEKYDKQLCHMVRETPEIYKRIVKPY 149
+NDIY+ + + +++ LI+PAT+ H+ KY + + V ET E Y +K
Sbjct: 58 SNDIYYSFKASVPMNIDFR------LIYPATEEHVRKYCSKRIY-VEETYEEYLDFIKS- 109
Query: 150 VDDMVNNGRLQWVQNILYNGAESDRVVFKYFDQESPKDGFVVLPDMKWDGVNMDALYLVA 209
+ +N W+ N++ Y D+E +++PD KW+ +D L+ +
Sbjct: 110 ASQITSN----WMDNLIAQDRSDLNEEIMYEDEE-----VIMIPDYKWNPQTVDLLHFLV 160
Query: 210 IVHRDDIKSLRDLRPEHQQWLIDMKNKIRSVVPSCYNYLVPADQLRLFIHYQPSYYHFHI 269
+ +K++RD+R Q L+D + K R+++ + + + + + +F HY+P+Y+ H+
Sbjct: 161 VFKDPGLKTIRDIRD--YQILVDAREKARNLLETRFG--LDFNHVFMFFHYRPTYFRLHL 216
Query: 270 HIVNVRHSGLGDGIAVGKAHLIEDVIENL 298
H++N++ + G+ ++ +A + DVI NL
Sbjct: 217 HVMNIKMAHEGN-VSCTRAIPLHDVIHNL 244
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.320 0.138 0.421
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,220,602
Number of Sequences: 60738
Number of extensions: 1042197
Number of successful extensions: 2521
Number of sequences better than 1.0e-05: 7
Number of HSP's better than 0.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 2493
Number of HSP's gapped (non-prelim): 7
length of query: 350
length of database: 30,389,216
effective HSP length: 107
effective length of query: 243
effective length of database: 23,890,250
effective search space: 5805330750
effective search space used: 5805330750
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)