ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI5916 good TBLD KOG0889 Cell cycle control, cell division, chromosome partitioning Histone acetyltransferase SAGA, TRRAP/TRA1 component, PI-3 kinase superfamily
r_klactVI5916 good TBLD KOG0889 Chromatin structure and dynamics Histone acetyltransferase SAGA, TRRAP/TRA1 component, PI-3 kinase superfamily
r_klactVI5916 good TBLD KOG0889 Replication, recombination and repair Histone acetyltransferase SAGA, TRRAP/TRA1 component, PI-3 kinase superfamily
r_klactVI5916 good TBLD KOG0889 Signal transduction mechanisms Histone acetyltransferase SAGA, TRRAP/TRA1 component, PI-3 kinase superfamily
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI5916 2062327 2051036 -3764
(3764 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YHR099w [TBLD] KOG0889 Histone acetyltransferase SAGA TRRAP/TRA1... 4620 0.0
SPBP16F5.03c [TBLD] KOG0889 Histone acetyltransferase SAGA TRRAP... 2000 0.0
SPAC1F5.11c [TBLD] KOG0889 Histone acetyltransferase SAGA TRRAP/... 1826 0.0
At2g17930 [TBLD] KOG0889 Histone acetyltransferase SAGA TRRAP/TR... 1123 0.0
Hs4507691 [TBLD] KOG0889 Histone acetyltransferase SAGA TRRAP/TR... 1089 0.0
7302249 [TBLD] KOG0889 Histone acetyltransferase SAGA TRRAP/TRA1... 1050 0.0
CE05429 [TBLD] KOG0889 Histone acetyltransferase SAGA TRRAP/TRA1... 303 5e-81
ECU05g0540 [TBLD] KOG0889 Histone acetyltransferase SAGA TRRAP/T... 166 7e-40
SPBC30D10.10c [L] KOG0891 DNA-dependent protein kinase 105 1e-21
SPBC216.07c [L] KOG0891 DNA-dependent protein kinase 78 2e-13
SPBC216.05 [TBLD] KOG0890 Protein kinase of the PI-3 kinase fami... 70 9e-11
CE28813 [L] KOG0891 DNA-dependent protein kinase 67 4e-10
CE07705 [L] KOG0891 DNA-dependent protein kinase 67 4e-10
YKL203c [L] KOG0891 DNA-dependent protein kinase 67 6e-10
YJR066w [L] KOG0891 DNA-dependent protein kinase 66 9e-10
Hs4826730 [L] KOG0891 DNA-dependent protein kinase 66 1e-09
At5g40820 [TBLD] KOG0890 Protein kinase of the PI-3 kinase famil... 60 9e-08
Hs4502325 [TBLD] KOG0890 Protein kinase of the PI-3 kinase famil... 58 3e-07
Hs22041606 [TBLD] KOG0890 Protein kinase of the PI-3 kinase fami... 58 3e-07
7297995 [L] KOG0891 DNA-dependent protein kinase 57 6e-07
>YHR099w [TBLD] KOG0889 Histone acetyltransferase SAGA TRRAP/TRA1 component
PI-3 kinase superfamily
Length = 3744
Score = 4620 bits (11984), Expect = 0.0
Identities = 2319/3804 (60%), Positives = 2897/3804 (75%), Gaps = 113/3804 (2%)
Query: 8 ERMDTFVERIRDTEDVAE-RHAIISELYDVLDVVTSSVEYDEFXXXXXXXXXXXXNDDQI 66
E+++ F R RD + + R++ +SELYD+++++ S +Y F + I
Sbjct: 5 EQIEQFASRFRDDDATLQSRYSTLSELYDIMELLNSPEDYHFFLQAVIPLLLNQLKEVPI 64
Query: 67 SMNASSPEHKLRNTCLELLNRCPLNDKMEPMAMEVLQCLLKILTLENDENGVLCMKILTS 126
S +A SPE KLRN+ L++ NRC +N +P AMEVL+ LL +L EN+ENG+LCMK+LT+
Sbjct: 65 SYDAHSPEQKLRNSMLDIFNRCLMNQTFQPYAMEVLEFLLSVLPKENEENGILCMKVLTT 124
Query: 127 LFKCYKQPLESEVNTFIKIIVGIYENVPNLVASTFLGEEETSSSTADSQ---------DF 177
LFK +K L+ ++++FI+II+ IY+N PNL+ TF + DS D
Sbjct: 125 LFKSFKSILQDKLDSFIRIIIQIYKNTPNLINQTFYEAGKAEQGDLDSPKEPQADELLDE 184
Query: 178 SNSNNEEDAFENLSAPSKKHLEKATES---------FKTLSECPITMVTLFSSYKHLILV 228
+ N+EE F + + ++ E +T S FK LSECPITMVTL+SSYK L
Sbjct: 185 FSKNDEEKDFPSKQSSTEPRFENSTSSNGLRSSMFSFKILSECPITMVTLYSSYKQLTST 244
Query: 229 DLPTFLPLVIDLLTLEVKQQQKSREELEAKGEKLIGMSSEIKNRSAFCDYVLAQIKATSF 288
LP F PL+++LL +++KQQQ++RE+ E++GE +S+EI NR A+CD++LAQIKATSF
Sbjct: 245 SLPEFTPLIMNLLNIQIKQQQEAREQAESRGEHFTSISTEIINRPAYCDFILAQIKATSF 304
Query: 289 LAYVFIRGYATDILKLHVKKVPDLVMRLLQDCPSELSSARKELLHATRHILSTSYKKLFL 348
LAYVFIRGYA + L+ +V VPDL++RLLQDCPSELSSARKELLHATRHILST+YKKLFL
Sbjct: 305 LAYVFIRGYAPEFLQDYVNFVPDLIIRLLQDCPSELSSARKELLHATRHILSTNYKKLFL 364
Query: 349 PKINLMFDQKVLIGDGFTSYETLRPLAYSTLADFIHNIRSDLAMADIEKTVKMYTSFLLD 408
PK++ +FD+++LIG+GFT +ETLRPLAYST+ADFIHNIRS+L +++IEKT+K+YT +LLD
Sbjct: 365 PKLDYLFDERILIGNGFTMHETLRPLAYSTVADFIHNIRSELQLSEIEKTIKIYTGYLLD 424
Query: 409 ESLALTVQIMSAKXXXXXXXXXXXXGKKDAYEVPKAKKLLMTIIEAYTSRFKLLNSQHKK 468
ESLALTVQIMSAK GK++ E P+AKKLLM II++Y +RFK LN Q+
Sbjct: 425 ESLALTVQIMSAKLLLNLVERILKLGKENPQEAPRAKKLLMIIIDSYMNRFKTLNRQYDT 484
Query: 469 ILKQHNVYEQSKNKKSKEIQDQLAKDRHDVDEYMVNILKSTDE--LLPSSVTVDTNADVD 526
I+K + YE K +K++++++ + + + +E+M +L+ +D+ L+P D N D
Sbjct: 485 IMKYYGRYETHKKEKAEKLKNSIQDNDKESEEFMRKVLEPSDDDHLMPQPKKEDINDSPD 544
Query: 527 GDITMSEEPDISEKGNSSVHSDNNTSLTVKNQDKNSDISFKENSVEILDFNDIQNHAPII 586
++T S++ VKN ++ DI+N+API+
Sbjct: 545 VEMTESDK-------------------VVKND---------------VEMFDIKNYAPIL 570
Query: 587 LFQATSNDPLKDAFYLYRTLLSFLKTIIHDLKVFNPPPDEYTTMNPKMWSALSRVFSYEE 646
L +NDP+KDAFYLYRTL+SFLKTIIHDLKVFNPPP+EYT NPK+W+++SRVFSYEE
Sbjct: 571 LLPTPTNDPIKDAFYLYRTLMSFLKTIIHDLKVFNPPPNEYTVANPKLWASVSRVFSYEE 630
Query: 647 VIVLKNLFHECIAGLHLFSSNPEGIDPSTVKAHFDITTPSLPVSATKDGRELMDYFAIIF 706
VIV K+LFHECI GL F + E + P T K HFDI+ PSLPVSATKD RELMDY A +F
Sbjct: 631 VIVFKDLFHECIIGLKFFKDHNEKLSPETTKKHFDISMPSLPVSATKDARELMDYLAFMF 690
Query: 707 MQIDSPVFNEIVESEIVFIYESLLRDSALLHVAQSFLTSEITSPNFTGILLKFLNSKLPE 766
MQ+D+ FNEI+E E+ F+YE +L DS LLHVAQSFLTSEITSPNF GILL+FL KL +
Sbjct: 691 MQMDNATFNEIIEQELPFVYERMLEDSGLLHVAQSFLTSEITSPNFAGILLRFLKGKLKD 750
Query: 767 LGNVDSNKSNILIRLFKLSFMSVNLFPITNEAVLLPHLNNLILDSLKYSTEAEEPLVYFY 826
LGNVD N SN+LIRLFKLSFMSVNLFP NE VLLPHLN+LIL+SLKYST AEEPLVYFY
Sbjct: 751 LGNVDFNTSNVLIRLFKLSFMSVNLFPNINEVVLLPHLNDLILNSLKYSTTAEEPLVYFY 810
Query: 827 LIRTLFRSIGGGRFENLYRSIKPILQTLLQSLNKMIQTACRPHERDLYVELCLTVPVRLS 886
LIRTLFRSIGGGRFENLYRSIKPILQ LLQSLN+MI TA PHER+LYVELC+TVPVRLS
Sbjct: 811 LIRTLFRSIGGGRFENLYRSIKPILQVLLQSLNQMILTARLPHERELYVELCITVPVRLS 870
Query: 887 VLAPYLNYLMKPLVYALVGFPELITQGLRTLELCIDNLTPEYLDPILEPVVGDVMKALFD 946
VLAPYL +LMKPLV+AL +P+L++QGLRTLELCIDNLT EY DPI+EPV+ DV KALF+
Sbjct: 871 VLAPYLPFLMKPLVFALQQYPDLVSQGLRTLELCIDNLTAEYFDPIIEPVIDDVSKALFN 930
Query: 947 LLKPQPFNHQISHTTVRILGKLGGRNRRFIETPKDLKTETELNIEVDAWFNIYGFNSEVP 1006
LL+PQPFNH ISH VRILGKLGGRNR+F++ P DL +TEL+I+ A F I G +VP
Sbjct: 931 LLQPQPFNHAISHNVVRILGKLGGRNRQFLKPPTDLTEKTELDIDAIADFKINGMPEDVP 990
Query: 1007 LSITPGVNSASDILKDYRVNLFYRKSAYKYLSTVLMLLLGSVGPIPKNLTECLQKGVKLL 1066
LS+TPG+ SA +IL+ Y+ ++ YRKSAYKYL+ VL+L+ S P N TE L+ V +
Sbjct: 991 LSVTPGIQSALNILQSYKSDIHYRKSAYKYLTCVLLLMTKSSAEFPTNYTELLKTAVNSI 1050
Query: 1067 NSEELEDNIQFNDEKVVDPGKFNNXXXXXXXXXXCMFYAASIKELQEDVTVLVNKIVTHF 1126
E + F+ E V+ ++N +FYA SIKEL++D L+N ++ HF
Sbjct: 1051 KLERIGIEKNFDLEPTVNKRDYSNQENLFLRLLESVFYATSIKELKDDAMDLLNNLLDHF 1110
Query: 1127 SLLQVNEALSEKRRQPHVFSVDVKQPDVSISCDILLKAIRNGLCSYLEDSRALAIEAIKK 1186
LLQVN L KR F++D+K P+ + ++L AI L Y+ + R + + A K+
Sbjct: 1111 CLLQVNTTLLNKRNYNGTFNIDLKNPNFMLDSSLILDAIPFALSYYIPEVREVGVLAYKR 1170
Query: 1187 VHDIGKVIYGDTLYLEHSFITTLMRTFIHQCYSETYYEKRAGMXXXXXXXXXXXXPVHYV 1246
+++ +IYG+ L L HSFI L + FIH CY ETYY KR G+ ++
Sbjct: 1171 IYEKSCLIYGEELALSHSFIPELAKQFIHLCYDETYYNKRGGVLGIKVLIDNVKSSSVFL 1230
Query: 1247 KNFQYGLTSGLLFVLKDTHAEAPLFITEDAKALLYEVIEVTCADVKEENLGDKHLQNSLT 1306
K +QY L +GLLFVLKDT +EAP IT+ A+ LL +++ +T ADVKEE+LG+K L+N+LT
Sbjct: 1231 KKYQYNLANGLLFVLKDTQSEAPSAITDSAEKLLIDLLSITFADVKEEDLGNKVLENTLT 1290
Query: 1307 DIVCELSNPTEIVRNVCQECLGKISTLTKIPVVTLMNHAKNFLLSPIFAKPLRALPFSMQ 1366
DIVCELSN VRN CQ+ L IS LT IP+V LM+H+K FLLSPIFAKPLRALPF+MQ
Sbjct: 1291 DIVCELSNANPKVRNACQKSLHTISNLTGIPIVKLMDHSKQFLLSPIFAKPLRALPFTMQ 1350
Query: 1367 IGNVDAVIYCLRLQNSFLKFDEELFRLLHESIALVDADDISLAST-QRITEYQTSQQLIK 1425
IGNVDA+ +CL L N+FL F+EELFRLL ESI L DA+D SL++ Q+ TEY TS+QL++
Sbjct: 1351 IGNVDAITFCLSLPNTFLTFNEELFRLLQESIVLADAEDESLSTNIQKTTEYSTSEQLVQ 1410
Query: 1426 LRVVCIRLLAQALLNPEFANAQNGSIRIKVLAVFFKTMLKPSPEIIEATYEGLKIVLAEN 1485
LR+ CI+LLA AL N EFA AQ G+IRI++LAVFFKTMLK SPEII TYE LK LAEN
Sbjct: 1411 LRIACIKLLAIALKNEEFATAQQGNIRIRILAVFFKTMLKTSPEIINTTYEALKGSLAEN 1470
Query: 1486 SKLPKELLQNGLKPMLMNLSDHQKLTVPGXXXXXXXXXXXIAYFKVEIGKKLSDHLDAWC 1545
SKLPKELLQNGLKP+LMNLSDHQKLTVPG IAYFKVEIG+KL DHL AWC
Sbjct: 1471 SKLPKELLQNGLKPLLMNLSDHQKLTVPGLDALSKLLELLIAYFKVEIGRKLLDHLTAWC 1530
Query: 1546 QIEVLDTLFGKEITQQTPTKIICSIFNIFHLLPPQAGIFLNELVFKLISLERKLRLQLDS 1605
++EVLDTLFG+++ +Q PTKII SI NIFHLLPPQA +FLN+L+ K++ LERKLRLQLDS
Sbjct: 1531 RVEVLDTLFGQDLAEQMPTKIIVSIINIFHLLPPQADMFLNDLLLKVMLLERKLRLQLDS 1590
Query: 1606 PFRVPLAKYLNRFHVQVLTYFKTNMRSRQLVLLMCSIIQKKEAPVLRKAFEPQLREFLKF 1665
PFR PLA+YLNRFH V YFK NM RQLVL MC+I+Q+ EA L + FE +L F F
Sbjct: 1591 PFRTPLARYLNRFHNPVTEYFKKNMTLRQLVLFMCNIVQRPEAKELAEDFEKELDNFYDF 1650
Query: 1666 YVEKIPENPVRVVSFFANSIDLVYVYHTSNEESWILENSDILFELKSMLTTVLKLINENS 1725
Y+ IP+N VRVVSFF N +DL +N + W+ + +++ +LK ML LK I ENS
Sbjct: 1651 YISNIPKNQVRVVSFFTNMVDLFNTMVITNGDEWLKKKGNMILKLKDMLNLTLKTIKENS 1710
Query: 1726 FNIDILQLNQSIEKFQMIYLAYLKQKKYDV-PLFLEMIQYSYDNDLKIPNEVNSFIFDDI 1784
F ID LQLNQSI KFQ +YL + + + D PL L+ I +S+ N +K + FIF +I
Sbjct: 1711 FYIDHLQLNQSIAKFQALYLRFTELSERDQNPLLLDFIDFSFSNGIKASYSLKKFIFHNI 1770
Query: 1785 ISCVDVQLKRKYILECLQFSLREERSLKARNFVIKRVVNSIMIHESTTKNSVDELISPDN 1844
I+ + + + +I + F L ++ L AR FV+K V+NS +I+E T S+ + D
Sbjct: 1771 IASSNKEKQNNFINDATLFVL-SDKCLDARIFVLKNVINSTLIYEVATSGSLKSYLVEDK 1829
Query: 1845 EI--FAFLNQHIWNPKSSSVVLNTVIGKLDSIRFELLQLTSILLKYAPTLLEPVKRDLIK 1902
+ L+ IW S++++ V+ D RFELLQL++I +K P ++ +K+D+IK
Sbjct: 1830 KPKWLELLHNKIWK-NSNAILAYDVLDHHDLFRFELLQLSAIFIKADPEIIAEIKKDIIK 1888
Query: 1903 FAWKFIKLEDIQLKQAAYVTTSLFISKFDLPVNIVTQVFVAILRVHQIEARFMVKESLDL 1962
F W FIKLED +KQ+AY+ TS FISKFD P+ +VTQVFVA+LR +EAR++VK+SLD+
Sbjct: 1889 FCWNFIKLEDTLIKQSAYLVTSYFISKFDFPIKVVTQVFVALLRSSHVEARYLVKQSLDV 1948
Query: 1963 LAPVVADRSKGSEEPTTWVNWVRRVILESNFQQNTILYQFLISQKDIFFPYKDMFIPNII 2022
L PV+ +R + P TW+NWV+RV++E++ QN ILYQFLIS D+FF +D+FI NII
Sbjct: 1949 LTPVLHERMNAAGTPDTWINWVKRVMVENSSSQNNILYQFLISHPDLFFNSRDLFISNII 2008
Query: 2023 SYIGRLTLLTNPSTENQTLTIDLCDLVMYWEKQTF------SAQSKDDPDVNMDGSEGIV 2076
++ ++T ++N ++++ TL IDL L++YWE +T + ++ D DV M S+ +
Sbjct: 2009 HHMNKITFMSNSNSDSHTLAIDLASLILYWENKTLEITNVNNTKTDSDGDVVMSDSKSDI 2068
Query: 2077 T---------------SSSTSLSQREAFAAFLIRFICVSNHRACETPLGSKALSVLTELL 2121
+S SL REA AFLIR++C SNHRA ET LG +A+++L+EL+
Sbjct: 2069 NPVEADTTAIIVDANNNSPISLHLREACTAFLIRYVCASNHRAIETELGLRAINILSELI 2128
Query: 2122 SIGYLPEAVVKLSYFEKFLIQQDLESANLLYYCMNALDVLDIIFRTKDPKWIINNLKTIQ 2181
S + VKL YFEKFLI QDL+S N+LYYCMNALDVL + F+ K +WI+ NL TIQ
Sbjct: 2129 SDKHWTNVNVKLVYFEKFLIFQDLDSENILYYCMNALDVLYVFFKNKTKEWIMENLPTIQ 2188
Query: 2182 TLLDKCLHANHHDLQEALQKVLSTVLTAVKDDDVPFESEEDTDSKVFVNLVSSIISENLN 2241
LL+KC+ ++HHD+QEALQKVL ++ A+K V EE++ K F+ +++S+I+++L
Sbjct: 2189 NLLEKCIKSDHHDVQEALQKVLQVIMKAIKAQGVSVIIEEESPGKTFIQMLTSVITQDLQ 2248
Query: 2242 GTTSVAAGVILCWTLFVNIPSQIDVLLPLLMKTFNKLCKDHLTISQPKDATAVEDARITT 2301
T+SV AGV L W LF+N P I LL LMKTF+KLCKDHL+ISQPKDA A+E+ARITT
Sbjct: 2249 ETSSVTAGVTLAWVLFMNFPDNIVPLLTPLMKTFSKLCKDHLSISQPKDAMALEEARITT 2308
Query: 2302 KLLKKVFYILSFKVSTLGDSRRPFLSTVALLIDRSMDQNFLQKIVLIAKNWVFTNEIFPT 2361
KLL+KV YILS KVS LGDSRRPFLSTVALLID SMDQNFL+KIV ++++W+F EIFPT
Sbjct: 2309 KLLEKVLYILSLKVSLLGDSRRPFLSTVALLIDHSMDQNFLRKIVNMSRSWIFNTEIFPT 2368
Query: 2362 VKEKAAILTKMLAFEIRGEPHLSKQFYEIILQLFENKKYNNSEITVRMEQPFLVGTRISD 2421
VKEKAAILTKMLAFEIRGEP LSK FYEI+L+LF+ + +NN+EITVRMEQPFLVGTR+ D
Sbjct: 2369 VKEKAAILTKMLAFEIRGEPSLSKLFYEIVLKLFDQEHFNNTEITVRMEQPFLVGTRVED 2428
Query: 2422 IKLRSKLMNILNGSLDNDIKERLYYVVRDQNWEFVADYMWLSQACQLLFGACVMEHRIKL 2481
I +R + M IL+ SL+ DIKERLYYV+RDQNWEF+ADY WL+QA QLL+G+ E + L
Sbjct: 2429 IGIRKRFMTILDNSLERDIKERLYYVIRDQNWEFIADYPWLNQALQLLYGSFNREKELSL 2488
Query: 2482 TEHFPLSPLSAIERNIIVEDEDKV--ITNSALESLIREHQSFIDKINSIKCCDIINPLVD 2539
+ LSP S ++ + E+ + V + + L + ++ H + + + I D I+ L++
Sbjct: 2489 KNIYCLSPPSILQE-YLPENAEMVTEVNDLELSNFVKGHIASMQGLCRIISSDFIDSLIE 2547
Query: 2540 IFYQSPEAVRATWVNVFPVAYKSIPRNEKYGFVRSLVALLSKDYHTKQASIHVNVISTML 2599
IFYQ P+A+ WV +FP YKSIP+NEKYGFVRS++ LLSK YHT+Q S NVI+ +L
Sbjct: 2548 IFYQDPKAIHRAWVTLFPQVYKSIPKNEKYGFVRSIITLLSKPYHTRQISSRTNVINMLL 2607
Query: 2600 ESVSKIESLELPPHLVRYLGITFNAWYQSIDLLEQIQETSNIDNSKILDTNEDALLELYS 2659
+S+SKIESLELPPHLV+YL I++NAWYQSI++LE IQ ++IDN+KI++ NEDALLELY
Sbjct: 2608 DSISKIESLELPPHLVKYLAISYNAWYQSINILESIQSNTSIDNTKIIEANEDALLELYV 2667
Query: 2660 SIQEDDMFYGLWRRKAKYTESSIALSYEQIGLWDKAQQMYEAAQVKARGGFLPYSESEYE 2719
++QE+DMFYGLWRR+AKYTE++I LSYEQIGLWDKAQQ+YE AQVKAR G LPYS+SEY
Sbjct: 2668 NLQEEDMFYGLWRRRAKYTETNIGLSYEQIGLWDKAQQLYEVAQVKARSGALPYSQSEYA 2727
Query: 2720 LWEDNWILCASKLQHWDILTELAKHEGFTDLLLECGWRVAEWNADREALEHSVKSVMDVP 2779
LWEDNWI CA KLQHWD+LTELAKHEGFTDLLLECGWRVA+WN+DR+ALE SVKSVMDVP
Sbjct: 2728 LWEDNWIQCAEKLQHWDVLTELAKHEGFTDLLLECGWRVADWNSDRDALEQSVKSVMDVP 2787
Query: 2780 TPRRQIFETFLALQQFGETKKGDQEVRRLCDEGIQLSLKKWHSLPKRYTPAHKALLHSFQ 2839
TPRRQ+F+TFLALQ F E++KGDQEVR+LCDEGIQLSL KW SLP RYTPAHK LLH FQ
Sbjct: 2788 TPRRQMFKTFLALQNFAESRKGDQEVRKLCDEGIQLSLIKWVSLPIRYTPAHKWLLHGFQ 2847
Query: 2840 QYMEFLEATQIYANLASTTVQNLDTKAQEIKRVLQAWRDRLPNIWDDITIWDDLVTWRQH 2899
QYMEFLEATQIYANL +TTVQNLD+KAQEIKR+LQAWRDRLPN WDD+ +W+DLVTWRQH
Sbjct: 2848 QYMEFLEATQIYANLHTTTVQNLDSKAQEIKRILQAWRDRLPNTWDDVNMWNDLVTWRQH 2907
Query: 2900 VFNVINSAYLPLVPALQQANSNSNINTHAYRGYHEIAWVINRFAHVARRHNMPDVCISQL 2959
F VIN+AYLPL+PALQQ+NSNSNINTHAYRGYHEIAWVINRFAHVAR+HNMPDVCISQL
Sbjct: 2908 AFQVINNAYLPLIPALQQSNSNSNINTHAYRGYHEIAWVINRFAHVARKHNMPDVCISQL 2967
Query: 2960 ARIYTLPNIEIQEAFLKLREQAKCHYQNMNELTTGLDVISNTNLVYFGTVQKAEFFTLKG 3019
ARIYTLPNIEIQEAFLKLREQAKCHYQNMNELTTGLDVISNTNLVYFGTVQKAEFFTLKG
Sbjct: 2968 ARIYTLPNIEIQEAFLKLREQAKCHYQNMNELTTGLDVISNTNLVYFGTVQKAEFFTLKG 3027
Query: 3020 MFLSKLRAHDEANQAFATAVQIDLNLAKAWAQWGFFNDRRLSEEPKNISFASNAMSCYLQ 3079
MFLSKLRA++EANQAFATAVQIDLNLAKAWAQWGFFNDRRLSEEP NISFASNA+SCYLQ
Sbjct: 3028 MFLSKLRAYEEANQAFATAVQIDLNLAKAWAQWGFFNDRRLSEEPNNISFASNAISCYLQ 3087
Query: 3080 AAGLYKNSKTRKLLSRILWLLGRDDSSNSLAYAFDSFRGEIPVWYWITFIPQLLTALSHK 3139
AAGLYKNSK R+LL RILWL+ DD+S L AFDSFRGEIPVWYWITFIPQLLT+LSHK
Sbjct: 3088 AAGLYKNSKIRELLCRILWLISIDDASGMLTNAFDSFRGEIPVWYWITFIPQLLTSLSHK 3147
Query: 3140 EAFLVRKILIRIAKSYPQALHFQLRTTKEDFAVIQRQSLALARTQGEPAETENQENSKHP 3199
EA +VR ILIRIAKSYPQALHFQLRTTKEDFAVIQRQ++A+ G+ +T N N +
Sbjct: 3148 EANMVRHILIRIAKSYPQALHFQLRTTKEDFAVIQRQTMAV---MGDKPDT-NDRNGR-- 3201
Query: 3200 SPDNSRTTSQNKSQDQDMYPNNRQPWEYLEELNGILKTAYPLLALSLESLVDQINQKFKT 3259
RQPWEYL+ELN ILKTAYPLLALSLESLV QIN +FK+
Sbjct: 3202 ----------------------RQPWEYLQELNNILKTAYPLLALSLESLVAQINDRFKS 3239
Query: 3260 NPDEDLFRLINVLLIDGTYNYNRLPYPREKPPLPSSTEANLIRFSENLLPPNIRVKFNAD 3319
DEDLFRLINVLLIDGT NYNRLP+PR+ P LP +TE NL++FS LL P IR KFNAD
Sbjct: 3240 TTDEDLFRLINVLLIDGTLNYNRLPFPRKNPKLPENTEKNLVKFSTTLLAPYIRPKFNAD 3299
Query: 3320 FIESKPDFEVYIKRLRFWRNRLENKLDRAPKVESMEAICPNLSNFHHQKFEDIKVPGQYL 3379
FI++KPD+E YIKRLR+WR RLENKLDRA K E++E +CP+LSNFHHQKFEDI++PGQYL
Sbjct: 3300 FIDNKPDYETYIKRLRYWRRRLENKLDRASKKENLEVLCPHLSNFHHQKFEDIEIPGQYL 3359
Query: 3380 LNKDNNTHFVKIGRFMPEVDFTRGTHTSHRRLTIRGHDGSLHSFAVQYPAVRHSRREERM 3439
LNKDNN HF+KI RF+P VDF RGTH+S+RRL IRGHDGS+HSFAVQYPAVRHSRREERM
Sbjct: 3360 LNKDNNVHFIKIARFLPTVDFVRGTHSSYRRLMIRGHDGSVHSFAVQYPAVRHSRREERM 3419
Query: 3440 FQLYRLLNERLRKNVQTRRRDIQFTVPIAVPLSPQVRVMSDSASFRTLHQIYDEFCAKKN 3499
FQLYRL N+ L KNV+TRRR IQF +PIA+PLSPQVR+M+DS SF TLH+I++EFC KK
Sbjct: 3420 FQLYRLFNKSLSKNVETRRRSIQFNLPIAIPLSPQVRIMNDSVSFTTLHEIHNEFCKKKG 3479
Query: 3500 MDRDAIQDFITEQLNVAHDKVLPPPDITAVKVEIFSSIHSLFIPSTLLKDYYSKLFSEFE 3559
D D IQDF+ ++LN AHD LP PD+T +KVEIF+SI ++F+PS +LKD+++ LF++FE
Sbjct: 3480 FDPDDIQDFMADKLNAAHDDALPAPDMTILKVEIFNSIQTMFVPSNVLKDHFTSLFTQFE 3539
Query: 3560 DFWLFRKQFASQYAAFVFMTFMLSINNRSPHKIFVDEKSGNVHTLEMLPSRYSYERVNQY 3619
DFWLFRKQFASQY++FVFM++M+ INNR+PHKI VD+ SGNV TLEMLPSR+ YERV
Sbjct: 3540 DFWLFRKQFASQYSSFVFMSYMMMINNRTPHKIHVDKTSGNVFTLEMLPSRFPYERVKPL 3599
Query: 3620 AKQFETNLPNSAPVFHNNEPVPFRMTPNIQKLIGDSAMEGVFSVGLFVIARALLEPDHEL 3679
K + +LP +P+FHNNEPVPFR+TPNIQ LIGDSA+EG+F+V LF I+RAL+EPD+EL
Sbjct: 3600 LKNHDLSLPPDSPIFHNNEPVPFRLTPNIQSLIGDSALEGIFAVNLFTISRALIEPDNEL 3659
Query: 3680 NTYLSLFIRDEVISWYSSMNRSIVEDPHLYAIVLTNVDLIIRKVAQFGHMSSSPSVATQY 3739
NTYL+LFIRDE+ISW+S+++R I+E+P L +V TNVDLIIRKVAQ GH++S+P+V TQ+
Sbjct: 3660 NTYLALFIRDEIISWFSNLHRPIIENPQLREMVQTNVDLIIRKVAQLGHLNSTPTVTTQF 3719
Query: 3740 VLDAISAAVSPRNLAKCDQSFMAW 3763
+LD I +AVSPRNLA+ D +FM W
Sbjct: 3720 ILDCIGSAVSPRNLARTDVNFMPW 3743
>SPBP16F5.03c [TBLD] KOG0889 Histone acetyltransferase SAGA TRRAP/TRA1 component
PI-3 kinase superfamily
Length = 3699
Score = 2000 bits (5182), Expect = 0.0
Identities = 1168/3265 (35%), Positives = 1821/3265 (55%), Gaps = 138/3265 (4%)
Query: 564 ISFKENSVEILDFNDIQNHAPIILFQATSNDPLKDAFYLYRTLLSFLKTIIHDLKVFNPP 623
I +EN ++ F + P Q + D LKD +L++ L +K ++ LK N P
Sbjct: 509 IKIEENKHDLPMFEN-----PTGAAQPSGLDKLKDCIFLFKNTLLGIKPVLFGLKQRNIP 563
Query: 624 PDEYTTMNPKMWSALSRVFSYEEVIVLKNLFHECIAGLHLFSSNPE-GIDPSTVKAHFDI 682
+ + WS + S EV++ + L E + G + ++ + G+ S+ +
Sbjct: 564 LANGSIFTAQEWSEKLHLSSTNEVLLFRRLLVESLKGFSYYQTDEKTGVFKSSKNLAYSQ 623
Query: 683 TTPSLPVSATK--DGRELMDYFAIIFMQIDSPVFNEIVESEIVFIYESLLRDSALLHVAQ 740
SL + +K + +EL++ A +F+ +D VF EI+ESE I+E L+ + ALLH+ Q
Sbjct: 624 LDSSLTTNPSKLLEEKELLEMLATLFLHLDPSVFVEILESEFPNIFECLVDNLALLHIFQ 683
Query: 741 SFLTSEITSPNFTGILLKFLNSKLPELGNVDSNKSNILIRLFKLSFMSVNLFPITNEAVL 800
++++E+TS N TGI+L F L ++G+ S + ++L+RLFKL+FM+VN+FP N VL
Sbjct: 684 FWMSNEVTSVNCTGIVLSFCCDNLAKIGSGQSTRVSVLLRLFKLAFMTVNVFPEKNAEVL 743
Query: 801 LPHLNNLILDSLKYSTEAEEPLVYFYLIRTLFRSIGGGRFENLYRSIKPILQTLLQSLNK 860
PH++ +I SL+ +T+A EPL Y YL++ LFR+I GG+F++LY+ I P+LQ +L+ N+
Sbjct: 744 RPHISYIISTSLELTTDAVEPLNYVYLMKALFRNISGGKFDSLYKEILPLLQVMLECFNR 803
Query: 861 MIQTACRPHERDLYVELCLTVPVRLSVLAPYLNYLMKPLVYALVGFPELITQGLRTLELC 920
+I T +++LY ELCLT+P+RLSVL P++N+LMKPL+ AL G PE+ +QGLR ELC
Sbjct: 804 LIFTVTSTSQKELYAELCLTLPIRLSVLLPHMNFLMKPLIVALKGPPEIASQGLRIFELC 863
Query: 921 IDNLTPEYLDPILEPVVGDVMKALFDLLKPQPFNHQISHTTVRILGKLGGRNRRFIETPK 980
+DNLT E+LDP+L+ ++ D++ L++ + N+Q+ + VRILGK+GGRNR+
Sbjct: 864 LDNLTQEFLDPLLDSIMPDLLICLWNHSRLNQSNNQLHQSAVRILGKMGGRNRQIYLGTF 923
Query: 981 DLKTETELNIEVDAWFNIYGFNSEVPLSITPGVNSASDILKDYRVNLFYRKSAYKYLSTV 1040
+ NI F+ G + L + + S+ +L + +L +K A++ +
Sbjct: 924 GFDFLQDENIFPSIQFSFQGSSQNFSLEHSKFLMSSCAVLNNQNSDLEEKKQAFQMVKNS 983
Query: 1041 LMLLLGSVGPIPKNLTECLQKGVKLLNSEELEDNIQFNDEKVVDPGK----------FNN 1090
+LL S P ++ E + + + + ++ N+Q + P K +N
Sbjct: 984 YLLLFASAKP-DEDFWESIDTMCRAV-VDRMDKNLQQVSNGRLCPDKDESYYLQRSIVSN 1041
Query: 1091 XXXXXXXXXXCMFYAASIKELQEDVTVLVNKIVTHFSLLQ-VNEALSEKRRQPHVFSVDV 1149
C+ + A +E +N+ + +L VN A S + + ++F D
Sbjct: 1042 IFKSLVGSMSCVEFVAEARET-------INRSLEWLIVLDLVNYADSLQIKDQNIF--DN 1092
Query: 1150 KQPDVSISCDILLKAIRNGLCSYLEDSRALAIEAIKKVHDIGKVIYGDTLYLEH--SFIT 1207
Q + + I LCS E++R+ A+ I + K++ TL + SF
Sbjct: 1093 LQSIKMLDLTTCINGIFESLCSENENTRSNALSCIDHYLNAHKMLLNTTLDISKLPSF-Q 1151
Query: 1208 TLMRTFIHQCYSETYYEKRAGMXXXXXXXXXXXXPVHYVKNFQYGLTSGLLFVLKDTHAE 1267
L+ F C+ E +Y+K AG ++++ + + L F+LKDT +
Sbjct: 1152 NLVTVFCQSCHKELWYQKNAGFLGLKAILSYDSHHKLWIQDRLHDILKALFFILKDTPTD 1211
Query: 1268 APLFITEDAKALLYEVIEVTCA--DVKEENLGDKHLQNSLTDIVCELSNPTEIVRNVCQE 1325
+ + ++ + ++ C DV ++ N+ + EL +P + VRN Q+
Sbjct: 1212 YGVLKLTEVRSFIVDITTQFCILQDVLAPKERANNIINAFSPFFLELLHPNDHVRNTVQQ 1271
Query: 1326 CLGKISTLTKIPVVTLMNHAKNFLLSPIFAKPLRALPFSMQIGNVDAVIYCLRLQNSFLK 1385
+ IS +K+ VV L+ K+ LLSPIF KPLRALPF++QIG++DA+ YCL SFL
Sbjct: 1272 AIENISNNSKLSVVDLLLPIKDRLLSPIFGKPLRALPFTIQIGHIDAITYCLHRSPSFLD 1331
Query: 1386 FDEELFRLLHESIALVDADDISLASTQRITEYQTSQQLIKLRVVCIRLLAQALLNPEFAN 1445
+EL+RL E+IAL DA+D +L + + ++ + S L KLR C+ LL +L+ +F
Sbjct: 1332 LTDELYRLFRETIALADAEDEALVTMLKTSQSKDSSSLRKLRATCLHLLFASLVAHKFDQ 1391
Query: 1446 AQNGSIRIKVLAVFFKTMLKPSPEIIEATYEGLKIVLAENSKLPKELLQNGLKPMLMNLS 1505
Q+ R K++A+FFK + P EI + L+ VL++N KLPKELLQ+GL+P+LMNLS
Sbjct: 1392 PQHAQTRTKIIAIFFKDLYSPHKEIYSVAIDALRHVLSQNQKLPKELLQSGLRPILMNLS 1451
Query: 1506 DHQKLTVPGXXXXXXXXXXXIAYFKVEIGKKLSDHLDAWCQIEVLDTLFGKEITQQTPTK 1565
DH KL+V G YFKVEIG+KL HL+ +VL+T + +
Sbjct: 1452 DHNKLSVNGLEGLSRLLRLLTNYFKVEIGRKLLQHLNVLSDSKVLETASLSLLKTNPRIE 1511
Query: 1566 IICSIFNIFHLLPPQAGIFLNELVFKLISLERKLRLQLDSPFRVPLAKYLNRFHVQVLTY 1625
II S+ N+F LPP + FL +L+ ++++E LR +SP R PL +++ Y
Sbjct: 1512 IIVSLVNVFRDLPPLSAQFLGDLLSSVVNIEAVLRKYSNSPLRKPLYSFMDLHANDTWMY 1571
Query: 1626 FKTNMRSRQLVLLMCSIIQKKEAPVLRKAFEPQLREFLKFYVEKIP-EN--PVRVVSFFA 1682
N R+ L+ + + LR+ + L+ + + EN P+ V A
Sbjct: 1572 ILNNARNGDLITRFVGALNDPMSEKLRETAGNYWGKLLELISQPVSVENLAPMYAVDIIA 1631
Query: 1683 NSIDLVYVYHTSNEESWILENSDILFELKSMLTTVLKLINENSFNIDILQLNQSIEKFQM 1742
V+ Y ++N ++ ++ I+ L L +L NE F L + + I
Sbjct: 1632 T----VFPYISANVDAGVISAKFIV--LSKSLYGMLSSYNEYLF----LPIRRCISSITK 1681
Query: 1743 IYLAYLKQKKYDVPLFLEMIQYSYDNDLKIPNEVNSFIFDDIISCVDVQLKRKYILECLQ 1802
+ L+ LK+ + + LE+ ++ D+D E + +I+ K+ L C
Sbjct: 1682 MLLSSLKKIEKKLEFSLEVFRFKADDDNDFLPEYIDSLCGCLITSTSAAEKKSIFLVCC- 1740
Query: 1803 FSLREERSLKA--RNFVIKRVVNSIMIHESTTKNSVDELISPDNEIFAFLNQHIWNPKSS 1860
S+ ++S++ + F++ +V+N ++ N +D+ ++ + H+W
Sbjct: 1741 -SIVGDKSVRPFFKAFLLDKVINPLVFKSCGENNFIDK------DVVHSVYTHVWRVSIR 1793
Query: 1861 SVVLNTVIGKLDSIRFELLQLTSILLKYAPTLLEPVKRDLIKFAWKFIKLEDIQLKQAAY 1920
V G DS ++ LT+ L KY LL ++ +I AW +IKLED +KQAAY
Sbjct: 1794 DFA--EVSGATDSFYMGIMCLTTALCKYHSALLNDYRKSVIMSAWNYIKLEDPMVKQAAY 1851
Query: 1921 VTTSLFISKFDLPVNIVTQVFVAILRVHQIEARFMVKESLDLLAPVVADRSKGSEEPT-- 1978
T + FIS +D P IVT V+V+IL+ +Q E R ++ SL L V+ R + T
Sbjct: 1852 ATIACFISAYDTPAKIVTPVYVSILKTYQPEVRAFIEFSLASLLSVLTARLSSPSDSTFP 1911
Query: 1979 TWVNWVRRVILES--NFQQNTILYQFLISQKDIFFPYKDMFIPNIISYIGRLTLLTNPST 2036
W R VI E Q +YQF+ D+FF FI +++ + +L ++ ST
Sbjct: 1912 LWAKLPRLVISEDVQGISQPLTVYQFICKAPDLFFSCCSHFIVPMVNALPKLVSFSSAST 1971
Query: 2037 ENQTLTIDLCDLVMYWEKQTFSAQSKDDPDVNMDGSEGIVTSSSTSLSQREAFAAFLIRF 2096
E + L +D+ + W+++ +++ + ++ S S EA FLI+F
Sbjct: 1972 EPRKLALDIVQTFINWQRKQNESENSE--------------TTLFSNSHIEAILTFLIKF 2017
Query: 2097 ICVSNHRACETPLGSKALSVLTELLSIGYLPEAVVKLSYFEKFLIQQDLESANLLYYCMN 2156
+ + E PL K LS+ +L S + + ++FEK L+ D N N
Sbjct: 2018 LSLFPEPVEENPLSKKGLSLFNDLFSFPRWKDCQLNSNFFEKILVDMDFNDNNYRTVA-N 2076
Query: 2157 ALDVLDIIFRTKDPKWIINNLKTIQTLLDKCLHANHHDLQEALQKVLSTVLTAVKDDDVP 2216
L V +I + + ++I I L+DK L + +L+++ +L ++
Sbjct: 2077 TLFVFGVILKNRGMEYIQREYSHIIALIDKSLRCGKLPVTHSLEQI---ILLLLQSHPTQ 2133
Query: 2217 FESEEDT-DSKVFVNLVSSIISENLNGTTSVAAGVILCWTLFVNIPSQIDVLLPLLMKTF 2275
E EEDT ++ F L+ S+I +NL T++ + + + + P +D LL L K F
Sbjct: 2134 AEEEEDTNEADDFKQLLLSVIHDNLAAATNIESAICYLQIVKSSNPEALDGLLLPLNKCF 2193
Query: 2276 NKLCKDHLT------ISQPKDATAVEDARITTKLLKKVFYILSFKVSTLGDSRRPFLSTV 2329
K+ +DH+ I T + +KLL I+ ++++LGD RR FLS V
Sbjct: 2194 QKVARDHIVACMQSAIQASGKVTLPSASDTVSKLLISFIEIIRVRMASLGDQRRWFLSVV 2253
Query: 2330 ALLIDRSMDQNFLQKIVLIAKNWVFTN-EIFPTVKEKAAILTKMLAFEIRGEPHLSKQFY 2388
L+++S + I+ + K WV + F TVKEK A+L KM FE R + L +
Sbjct: 2254 VQLLEKSSSFELCEHILNVTKEWVIVKRDSFLTVKEKTALLLKMRTFEGRFDNKLYIEAC 2313
Query: 2389 EIILQLFENKKYNNSEITVRMEQPFLVGTRISDIKLRSKLMNILNGSLDNDIKERLYYVV 2448
+++ ++ + + ++E+T R++Q FL+ T D K+R M+I + S+ ++ RL +++
Sbjct: 2314 DLLSTIYRDPIFAHTELTARLKQAFLLATASKDTKIRMDFMDIFDSSMSRNVYSRLTFIL 2373
Query: 2449 RDQNWEFVADYMWLSQACQLLFGACVMEHRIKLTEH---FPLSPLSAIERNIIVEDEDKV 2505
+W+ + W+ QA +L GA + ++LT++ F P++ + + E K
Sbjct: 2374 DATSWDTIPSIYWIKQANYILLGAINAKQPVRLTDNSLRFAPVPMTKPILSSLPEVFSKH 2433
Query: 2506 ITNSALE----SLIREHQSFIDKINSIKCCDIINPLVDIFYQSPEAVRATWVNVFPVAYK 2561
SA+ + ++ F+ + + II PL I S W +FP+A+K
Sbjct: 2434 -NGSAIPLGRFTFFKQLDLFLKRNKELTVQKIIFPLAHIQMLSDADANKLWQYIFPLAWK 2492
Query: 2562 SIPRNEKYGFVRSLVALLSKDYHTKQASIHVNVISTMLESVSKIES-LELPPHLVRYLGI 2620
+ + + +SL+ LL++DYH KQ + NVIST++ S K + LELPPHLV+YLG
Sbjct: 2493 ILSSDNRSDLSKSLIYLLTRDYHIKQVNNRPNVISTLVSSFVKCAAKLELPPHLVKYLGK 2552
Query: 2621 TFNAWYQSIDLLEQIQETSNID---NSKILDTNEDALLELYSSIQEDDMFYGLWRRKAKY 2677
+ +++S+ LLE IQ + D N+K+ ++ DA+ ELY+S+ EDDMFYG WRR KY
Sbjct: 2553 LYGVYHESVSLLE-IQLSDKYDMYQNAKVQESRADAVAELYASLNEDDMFYGHWRRNCKY 2611
Query: 2678 TESSIALSYEQIGLWDKAQQMYEAAQVKARGGFLPYSESEYELWEDNWILCASKLQHWDI 2737
++ +ALSYEQ+G+W +AQQ+YE AQ KAR +P+SESEY LWED W++CA KLQ WD+
Sbjct: 2612 LQTQVALSYEQLGMWGRAQQLYEQAQTKARSEAIPFSESEYNLWEDQWVMCAQKLQQWDV 2671
Query: 2738 LTELAKHEGFTDLLLECGWRVAEWNADREALEHSVKSVMDVPTPRRQIFETFLALQQFGE 2797
LTELAKHEG ++LLLEC WR+++W+ +RE+LE ++KS+ DVPTPR+ F+ F+ LQ+
Sbjct: 2672 LTELAKHEGSSELLLECAWRISDWSNNRESLEVAIKSLSDVPTPRKLTFQCFMTLQKSVS 2731
Query: 2798 TKKGDQEVRRLCDEGIQLSLKKWHSLPKRYTPAHKALLHSFQQYMEFLEATQIYANLAST 2857
+E +++ E IQL+L KWH LP++ +H +LLH FQQ++E EA IY++L +
Sbjct: 2732 QPLAIKEFQQVLSEAIQLALIKWHQLPEKVNQSHYSLLHLFQQFVELQEAATIYSHLNAI 2791
Query: 2858 TVQNLDTKAQEIKRVLQAWRDRLPNIWDDITIWDDLVTWRQHVFNVINSAYLPLVPALQQ 2917
QNL T Q IK LQ W++RLPN+WDDI +W DL++WRQ VF++IN YLPLVP +Q
Sbjct: 2792 NFQNLPTNVQLIKSALQVWQERLPNVWDDINLWRDLISWRQIVFSMINRVYLPLVPTIQA 2851
Query: 2918 ANSNSNIN----THAYRGYHEIAWVINRFAHVARRHNMPDVCISQLARIYTLPNIEIQEA 2973
+S + N + +RGYHE AW+INRFAHVAR+H +P VC++QL +IYTLPNIEIQEA
Sbjct: 2852 NSSADSSNPPNTSFLFRGYHETAWLINRFAHVARKHKLPSVCLNQLTKIYTLPNIEIQEA 2911
Query: 2974 FLKLREQAKCHYQNMNELTTGLDVISNTNLVYFGTVQKAEFFTLKGMFLSKLRAHDEANQ 3033
F KLREQ C+ QN +L TGL+V++NTNL+YF + QK+EF TLKG FL KL +EANQ
Sbjct: 2912 FYKLREQVLCYLQNPRDLKTGLEVVTNTNLMYFNSRQKSEFVTLKGKFLEKLNRGEEANQ 2971
Query: 3034 AFATAVQIDLNLAKAWAQWGFFNDRRLSEEPKNISFASNAMSCYLQAAGLYKNSKTRKLL 3093
+A AVQIDL L KAWA+WG +ND ++ P N+S A NA+SCYLQAAG Y++SK RK+L
Sbjct: 2972 MYAAAVQIDLGLPKAWAEWGRYNDLLFNKSPDNLSAACNAISCYLQAAGTYQSSKARKML 3031
Query: 3094 SRILWLLGRDDSSNSLAYAFDSFRGEIPVWYWITFIPQLLTALSHKEAFLVRKILIRIAK 3153
+R+LWLL +DS+ ++ AF+S++G+IPVW+W+TFIPQLL +LS + +L +IAK
Sbjct: 3032 ARVLWLLSLNDSAGTIVKAFESYKGDIPVWHWLTFIPQLLNSLSKGDTKCAPVVLKKIAK 3091
Query: 3154 SYPQALHFQLRTTKEDFAVIQRQSLALARTQGEPAETENQENSKHPSPDNSRTTSQNKSQ 3213
SYPQAL F LRT +ED A ++R +A ++ N++ S S S N
Sbjct: 3092 SYPQALFFTLRTAREDIAQVKRTEMAAWKSNTTDENKRNEDILSIQSNFLSTNQSTNAPA 3151
Query: 3214 DQDMYPNNRQPWEYLEELNGILKTAYPLLALSLESLVDQINQKFKTNPDEDLFRLINVLL 3273
+++ WEY++E+ ILKTAYPLLAL++E+LVDQI KFK D D FRL+ LL
Sbjct: 3152 TNKEDGLSKKVWEYIDEIMSILKTAYPLLALTMETLVDQIQAKFKCKNDGDAFRLVVALL 3211
Query: 3274 IDGTYNYNRLPYPREKPPLPSSTEANLIRFSENLLPPNIRVKFNADFIESKPDFEVYIKR 3333
D + RL ++ LPSSTE+NL F++N+LP + F DFI + + YI +
Sbjct: 3212 NDAVQHSIRLGIVTDEMKLPSSTESNLSLFADNILPDYCKQLFKEDFIVNSNGLKSYIFK 3271
Query: 3334 LRFWRNRLENKLDRAPKVESMEAICPNLSNFHHQKFEDIKVPGQYLLNKDNNTHFVKIGR 3393
LR WR+ E L + PK + +E L FHHQKF++I+VPGQYLL+KDNN F I R
Sbjct: 3272 LRKWRSYFERLLSKVPKKQYLEQYSSFLCEFHHQKFDEIEVPGQYLLHKDNNNSFSCIER 3331
Query: 3394 FMPEVDFTRGTHTSHRRLTIRGHDGSLHSFAVQYPAVRHSRREERMFQLYRLLNERLRKN 3453
F+PEV+ G +RRL+IR + G++H F +QYP+ R+SRREER QL R LN+ L N
Sbjct: 3332 FLPEVELIVGHGVCYRRLSIRSNGGTIHPFVIQYPSARNSRREERFMQLTRYLNDALALN 3391
Query: 3454 VQTRRRDIQFTVPIAVPLSPQVRVMSDSASFRTLHQIYDEFCAKKNMDRDAIQDFITEQL 3513
+TRRR ++F +P +PLS +R++ D S TL +IY+ + + N RD ++ T +L
Sbjct: 3392 CETRRRCLKFYIPAVIPLSSHIRLLEDQPSSITLQKIYEIYSERNNFSRDDPKELFTNEL 3451
Query: 3514 --------------NVAHDKVLPPPDITAVKVEIFSSIHSLFIPSTLLKDYYSKLFSEFE 3559
+ +K+ + + ++ +F +I L+ PST+LKDY+S +F+ +
Sbjct: 3452 SKHMMELNSQISQESTDAEKLANRKQLFSRRIGMFENIQKLYSPSTILKDYFSSIFTNYS 3511
Query: 3560 DFWLFRKQFASQYAAFVFMTFMLSINNRSPHKIFVDEKSGNVHTLEMLPSRYSYERVNQY 3619
D WLFRK F+ QYA F F+T++LSINNR P K+ SG V T E LPS S
Sbjct: 3512 DLWLFRKNFSYQYACFSFITYILSINNRIPAKLVFSRDSGGVWTTEALPSMVS------- 3564
Query: 3620 AKQFETNLPNSAPVFHNNEPVPFRMTPNIQKLIGDSAMEGVFSVGLFVIARALLEPDHEL 3679
S PV+HN E VPFR TPNI++ IG + EG+ + IARAL +PD +L
Sbjct: 3565 ----------STPVYHNGEIVPFRFTPNIKEFIGKTCTEGLLGPSIMAIARALSKPDFDL 3614
Query: 3680 NTYLSLFIRDEVISWYSSMNRSIVEDPHLYAIVLTNVDLIIRKVAQFGHMSSSPSVATQY 3739
+ YL +FIRD++ W + + + D + V +N DLI+R+VA ++ Q
Sbjct: 3615 DMYLGIFIRDDLFWWLAQQTKGVPADFSMLNKVNSNTDLIMRRVASLSQVAYGNLPVNQT 3674
Query: 3740 VLDAISAAVSPRNLAKCDQSFMAWL 3764
+D ++ A S + LA+ D + WL
Sbjct: 3675 AIDYLAQASSSKVLAQMDVLWAPWL 3699
Score = 212 bits (539), Expect = 1e-53
Identities = 127/392 (32%), Positives = 206/392 (52%), Gaps = 7/392 (1%)
Query: 32 ELYDVLD--VVTSSVEYDEFXXXXXXXXXXXXNDDQISMNASSPEHKLRNTCLELLNRCP 89
E+ D LD +VT ++ F + + ++ + H+LR LELL +
Sbjct: 67 EIRDALDDVLVTEKTNFETFIPLLEDTLSLLEKERPV-FSSLAATHRLRIALLELLKKSG 125
Query: 90 LNDKMEPMAMEVLQCLLKILTLENDENGVLCMKILTSLFKCYKQPLESEVNTFIKIIVGI 149
E LL+I+ +N+E VL +K++ LFK + + V F+ I+V
Sbjct: 126 SYKGFEAFVNRTFAVLLRIVVNDNEEMAVLALKLVVLLFKDHSSLAKGHVQEFLSIVVEN 185
Query: 150 YENVPNLVASTFLGEEETSSSTADSQDFSNSNNEEDAFENLSAPSKKHLEKATESFKTLS 209
Y+++ +V+ F ++ +T S S +++ A + K + KA+ SFK +
Sbjct: 186 YKSMTTVVSEAF--PPRSAPNTPSSHPMSAASSASPAEIGMEHAGPKMIPKASSSFKVTA 243
Query: 210 ECPITMVTLFSSYKHLILVDLPTFLPLVIDLLTLEVKQQQKSREELEAKGEKLIGMSSEI 269
E PI + LF +YK LI LP PLV+ ++L Q ++R E++ E IG+ +
Sbjct: 244 EFPIIVFLLFQTYKDLIPKMLPLLAPLVLQFISLRPPPQAEARRLAESQKEVFIGVVPSL 303
Query: 270 KNRSAFCDYVLAQIKATSFLAYVFIRGYATDILKLHVKKVPDLVMRLLQDCPSELSSARK 329
+ + D + AQIK+ SFLAY+ +R + LK +P ++L DCPSEL R+
Sbjct: 304 RRNHLYNDLISAQIKSFSFLAYL-LRSFGA-ALKQFESSIPICTLQLFMDCPSELYQTRR 361
Query: 330 ELLHATRHILSTSYKKLFLPKINLMFDQKVLIGDGFTSYETLRPLAYSTLADFIHNIRSD 389
ELL ATRH+LST Y + FLP ++ + D K+L+G G TS +LRP+A+S LAD +H +R +
Sbjct: 362 ELLVATRHVLSTDYLRGFLPYVDQLLDTKILVGSGITSQHSLRPMAFSMLADMLHYVRME 421
Query: 390 LAMADIEKTVKMYTSFLLDESLALTVQIMSAK 421
L+ I K + +Y S L+D+ +Q M+ K
Sbjct: 422 LSPQQIYKVILLYFSILMDDFYTSAIQAMATK 453
>SPAC1F5.11c [TBLD] KOG0889 Histone acetyltransferase SAGA TRRAP/TRA1 component
PI-3 kinase superfamily
Length = 3655
Score = 1826 bits (4729), Expect = 0.0
Identities = 1087/3255 (33%), Positives = 1748/3255 (53%), Gaps = 176/3255 (5%)
Query: 596 LKDAFYLYRTLLSFLKTIIHDLKVFNPPPDEYTTMNPKMWSALSRVFSYEEVIVLKNLFH 655
+ D +L++ L+ L+ +++ L+ E + + +S E + + LF
Sbjct: 491 VNDGSFLFKNLMFGLRALMYGLRTCKSRCIE---IGGEQFSGFLTNIKPFEAVTFQKLFF 547
Query: 656 ECIAGLHLFSSNPEGIDPSTVKAHFDITTPSLP-VSATKDGRELMDYFAIIFMQIDSPVF 714
E G F ++ + P++ + KD ++ ++ FA IF+ ++ +F
Sbjct: 548 EVGKGFSYFRPEQVYLETFFCCEEESLDRPAISTLPRNKDEKDCLEVFATIFIHLEPSIF 607
Query: 715 NEIVESEIVFIYESLLRDSALLHVAQSFLTSEITSPNFTGILLKFLNSKLPELGNVDSNK 774
++ E+ + ++ L ++ L H+ Q L++E TS F ILL+FL S++ ELG+ D
Sbjct: 608 LKVFETNLPTFFDQLKKNLTLFHIPQFLLSNESTSSKFLNILLRFLLSRIEELGSSDIRH 667
Query: 775 SNILIRLFKLSFMSVNLFPITNEAVLLPHLNNLILDSLKYSTEAEEPLVYFYLIRTLFRS 834
++L+RLF+LSF++V++F NE VL P+++ +I+ +K + + L Y+YL+R LFR
Sbjct: 668 GSVLLRLFRLSFVTVSMFATENEPVLRPYVSEIIVKCMKLAPNSANSLNYYYLLRALFRG 727
Query: 835 IGGGRFENLYRSIKPILQTLLQSLNKMIQTACRPHERDLYVELCLTVPVRLSVLAPYLNY 894
IGGGRFE+LY+ + P+L LL++ N ++ +A P E+DL+ ELCLT+PVRLS+L PY++Y
Sbjct: 728 IGGGRFESLYKEVMPLLHALLEAFNSLLISARTPKEKDLFTELCLTIPVRLSLLLPYMSY 787
Query: 895 LMKPLVYALVGFPELITQGLRTLELCIDNLTPEYLDPILEPVVGDVMKALFDLLKPQPFN 954
LM+PLV +L EL++QGLRT ELC+DNLTP++LDPI+ P + D+M AL+ L+P P+N
Sbjct: 788 LMRPLVMSLKSSQELVSQGLRTFELCLDNLTPDFLDPIMAPYIEDLMNALWSHLQPLPYN 847
Query: 955 HQISHTTVRILGKLGGRNRRFIETPKDLKTETELNIEVDAWFNIYGFNSEVPLSITPGVN 1014
+ SHT ++ILGKLGGRNR+ ++ + LK E N + +I G L T V+
Sbjct: 848 YNHSHTALKILGKLGGRNRKLLDRVQSLKNSPEPNNDFTLLLSIKGVKQPQLLHYTQYVD 907
Query: 1015 SASDILKDYRVNLFYRKSAYKYLSTVLMLLLGSVGPIPKNLTECLQKGVKLLNSEELEDN 1074
A ++L +L ++ A+ Y+ + L + + T L ++ + + N
Sbjct: 908 EAVNLLSSPSSDLEVKQQAFTYVCNISKLYV-----YKSDATNSLASSIRCTADKISKSN 962
Query: 1075 IQFNDEKVVDPGKFNNXXXXX------------XXXXXCMFYAASIKELQEDVTVLVNKI 1122
F V P + +F+A ++ EL+E+ + K+
Sbjct: 963 FDFRRPYSVIPSRMTGRSSFTQLSDDSDETIILASATYGLFFATTVDELREEAYFWLEKL 1022
Query: 1123 VTHFSLLQVNEALSEKRRQPHVFSVDVKQPDVSISCDILLKAIRNGLCSYLEDSRALAIE 1182
+ + + A + F+ ++ Q +V IS + +C+
Sbjct: 1023 AVNVIVHDIFYAFDVIQGNHSKFTTNL-QKEVIISPHYFAHCLSEVVCNDNSKMGDAVKH 1081
Query: 1183 AIKKVHDIGKVIYGDTLYLEHSFIT----TLMRTFIHQCYSETYYEKRAGMXXXXXXXXX 1238
+K + + I+ + E +FI L+ F H+CY +Y+K G
Sbjct: 1082 VLKFMFSFLESIFENP---ERAFILPIFEVLLSDFRHKCYDPHWYKKYGGCFGLECLIEQ 1138
Query: 1239 XXXPVHYVKNFQYGLTSGLLFVLKDTHAEAPLFITEDAKALLYEVIEVTCADVKEENLGD 1298
++ + Q + + L F LKDT +E P + +L ++ A E
Sbjct: 1139 DHSS-KWLFDRQVDILTALFFTLKDTTSEVPTVCKDHVMDVLKQLFRKIYASKDTEIA-- 1195
Query: 1299 KHLQNSLTDIVCELSNPTEIVRNVCQECLGKISTLTKIPVVTLMNHAKNFLLSPIFAKPL 1358
L +V ELSN +VR+ Q+ L +S L+ P+V L++ K LLSPIFAKPL
Sbjct: 1196 ---PGILGHLVLELSNHNSVVRSSTQKLLSLLSELSNTPIVKLVSPFKERLLSPIFAKPL 1252
Query: 1359 RALPFSMQIGNVDAVIYCLRLQNSFLKFDEELFRLLHESIALVDADDISLASTQRITEYQ 1418
RALPF +QIG++DAV YC+ L + + F +EL RL+HE+ AL +ADD +L + + ++
Sbjct: 1253 RALPFHIQIGHIDAVNYCISLGSELITFSDELIRLIHETTALAEADDDALIGIGKTSHFK 1312
Query: 1419 TSQQLIKLRVVCIRLLAQALLNPEFANAQNGSIRIKVLAVFFKTMLKPSPEIIEATYEGL 1478
+ LI+LRVVC+ LL+ +L +F N Q+ +R ++ VFFK++ S E+IEA GL
Sbjct: 1313 NAALLIRLRVVCVELLSTCILKIDFNNPQHAHLREGIIVVFFKSLYAKSKELIEAASLGL 1372
Query: 1479 KIVLAENSKLPKELLQNGLKPMLMNLSDHQKLTVPGXXXXXXXXXXXIAYFKVEIGKKLS 1538
K L E+ KL KELLQ L+P+L N+SD+++L+V G YFKVEIG+KL
Sbjct: 1373 KNALQEDQKLSKELLQTTLRPILYNISDYRRLSVAGLEGLGRLLRLLTNYFKVEIGRKLL 1432
Query: 1539 DHLDAWCQIEVLDTLFGKEITQQTPTKIICSIFNIFHLLPPQAGIFLNELVFKLISLERK 1598
DHL A + + + QT KI+ ++ ++FHLLP A F++EL+ ++ +
Sbjct: 1433 DHLKALLENVDFQKVSSLPLFCQTEMKIVRALIDLFHLLPNNANRFMDELLICVVEFSLR 1492
Query: 1599 LRLQLDSPFRVPLAKYLNRFHVQVLTYFKTNMRSRQLVLLMCSIIQKKEAPVLRKAFEPQ 1658
L+ + F PL KY+NR+ +F + +++ K++ L +
Sbjct: 1493 LQRTFPNYFSEPLLKYVNRYPEDAWKFFMVRYDEAAFTSVFVELLRLKDSDPLLSVVKDN 1552
Query: 1659 LREFLKFYVEKIPENPVRVVSFFANSIDLVYVYHTSNEESWILENSDILFELKSMLTTVL 1718
F +I SF +S ++ + S+ + +D + +
Sbjct: 1553 WLFFQTILTNEINTVTANRYSFALDSAIVIL----QRDPSFFKDKNDFFRGSMDAVLAIS 1608
Query: 1719 KLINENSFNIDILQLNQSIEKFQMIYLAYLKQKKYDVPLFLEMIQYSYDNDLKIPNEVNS 1778
L+ S ++ N + + L + YD+ + Y+YD+ LK+ + +
Sbjct: 1609 HLVENESILESMVFWNDLLVRTSTFLL-----EVYDLCI------YNYDDGLKLLSCFHM 1657
Query: 1779 F---IFDDIISCVDVQLKRKYILECLQFSLREERSL---KARNFVIKRVVNSIMIHESTT 1832
+ + +++S + L +K L+ +++ +L K F++K + I++ T
Sbjct: 1658 YKNSLAKNLVSDLTAHLVKKIEEPDLENNVKLILNLILSKDYGFLLKENLAGILL---TY 1714
Query: 1833 KNSVDELISPDNEIFAFLNQHIWNPKSSSVVLNTVIGKLDSIRFELLQLTSILLKYAPTL 1892
N + N+IF+ + + S++V N + I+ LQ+ S LK P +
Sbjct: 1715 LNQNVSSLEKCNQIFSIFYEVFFQHPSTNVYAND-----EGIKIGALQIISFFLKNVPEI 1769
Query: 1893 LEPVKRDLIKFAWKFIKLEDIQLKQAAYVTTSLFISKFDLPVNIVTQVFVAILRVHQIEA 1952
+ +++K F ED+ +KQ + SLFI + P +V V++A+L+ IE
Sbjct: 1770 TVQHQTEMLKMCSLFGNSEDVMIKQLSIYVMSLFILRSQFPYELVNVVYMALLKSSPIEV 1829
Query: 1953 RFMVKESLDLLAPVVADRSKGSEEPTTWVNWVRRVILES--NFQQNTILYQFLISQKDIF 2010
R +VK S D + + S++ W +VI N Q +Y F+ S DIF
Sbjct: 1830 RHLVKSSFDNIFSYIFSEEPESKKSPIWFELPLQVISSQSQNISQLLNVYDFISSHSDIF 1889
Query: 2011 FPYKDMFIPNIISYIGRLTLLTNPSTENQTLTIDLCDLVMYWEKQTFSAQSKDDPDVNMD 2070
++ ++P +I + + + NP+ E + L++ L +++ W +D + +D
Sbjct: 1890 IEHRGRYVPILIDSLYKFGAIPNPNPEIRALSLGLIKVLLEW----------NDLQLKVD 1939
Query: 2071 GSEGIVTSSSTSLSQREAFAAFLIRFICVSNHRACETPLGSKALSVLTELLSIGYLPEAV 2130
E S +Q+ A ++L RF+C+ + E L S+A+S+L LLS G
Sbjct: 1940 QKEIF------SNNQKRAILSYLFRFVCLFSEPFTEG-LCSEAISLLERLLSSGTWASLG 1992
Query: 2131 VKLSYFEKFLIQQDLESANLLYYCMNALDVLDIIFRTKDPKWIINNLKTIQTLLDKCLHA 2190
+KLS+F K + D AN + + N+L L I+ D WI NL ++ LL+K L
Sbjct: 1993 MKLSFFTKSITHFDATDANSVMFA-NSLRTLSIVVGHSDSAWIEENLSDLKFLLEKSLEN 2051
Query: 2191 NHHDLQEALQKVLSTVLTAVKDDDVPFESEEDTDSKVFVNLVSSIIS---ENLNGTTSVA 2247
+Q A+ +ST+LT + +F ++ +SI S L + +
Sbjct: 2052 ESVGVQSAIGNFVSTILTLSNTHP------SIAGNPIFNDIWTSIASWTERRLQSCSQIE 2105
Query: 2248 AGVILCWTLFVNIPSQIDVLLPLLMKTFNKLCKDHLTISQPKDATAVE-------DARIT 2300
+ F + LLP M+ F+K+ K+ L++ ++ D R++
Sbjct: 2106 VTLPCVECFFKYKKDALHTLLPGFMRCFHKVAKEFLSLGSQPSGNSLNLQIVNAVDERVS 2165
Query: 2301 TKLLKKVFYILSFKVSTLGDSRRPFLSTVALLIDRSMDQNFLQKIVLIAKNWVFTNEI-F 2359
+LK + + +S LGD RR FLS + +I++S ++ I + W+ + +
Sbjct: 2166 --ILKSMIELGCSYISYLGDQRRWFLSALVQIIEKSSSYEICNYLLEIVRGWIMNSPVPV 2223
Query: 2360 PTVKEKAAILTKMLAFEIRGEPH----LSKQFYEIILQLFENKKYNNSEITVRMEQPFLV 2415
PTVKEKAA+L KM+ FE R + L ++ I ++E + Y NSE+T R+E +L+
Sbjct: 2224 PTVKEKAALLLKMVTFEGRFSQNEQNDLFNKYLSFIADIYEMEPYKNSELTFRLEAVYLL 2283
Query: 2416 GTRISDIKLRSKLMNILNGSLDNDIKERLYYVVRDQNWEFVADYMWLSQA------CQLL 2469
GTR+++ KL+ + + LN S +D+ R +++ Q+WE +++ W+ Q C L
Sbjct: 2284 GTRVANKKLKERFIKGLNSSFPSDLFSRFQFLLGSQHWESLSNTYWIVQLNIFLSRCFDL 2343
Query: 2470 FGACVMEHRIKLTEHFPLSPLSAIERNIIVEDEDKVITNSALESLIREHQSFIDKINSIK 2529
C + KL F + E + +++ N+ L+ I + NS+
Sbjct: 2344 NQRCQFYKKPKLFSCFSIYCREFDEDLTSQAQDTEMLHNNLLKYGIIDFNQ-----NSML 2398
Query: 2530 CCDIINPLVDIFYQSPEAVRATWVNVFPVAYKSIPRNEKYGFVRSLVALLSKDYHTKQAS 2589
D + P++ + + + + W + F + S ++E + S+++ LS++YH +
Sbjct: 2399 VSDFVLPVLSLQFSNSKIAEYLWRDFFNASVCSFTKDEIPLCIGSIISFLSREYHIRLLG 2458
Query: 2590 IHVNVISTMLES-VSKIESLELPPHLVRYLGITFNAWYQSIDLLEQ-IQETSNIDNSKIL 2647
NV+ T+L S VS + LPPHL+ YL T+ + I LLE +Q + ++
Sbjct: 2459 KTPNVLETILTSIVSSDMPIPLPPHLLVYLSKTYGLHHYCILLLENSLQNNPGLSEDELT 2518
Query: 2648 DTNE---DALLELYSSIQEDDMFYGLWRRKAKYTESSIALSYEQIGLWDKAQQMYEAAQV 2704
++ DAL ++Y S+ E D+++GLWRR+A + E+ +A S+EQ W+KAQ +YE AQ+
Sbjct: 2519 VYHKSCLDALSDIYYSLDEHDLYHGLWRRRANFLETEVATSHEQCHEWEKAQLVYEHAQL 2578
Query: 2705 KARGGFLPYSESEYELWEDNWILCASKLQHWDILTELAKHEGFTDLLLECGWRVAEWNAD 2764
K G LPYS +E+ W D+WILCA KL WD+L + +K EG +L LEC WR+++W+ +
Sbjct: 2579 KVCTGSLPYSPTEHGFWLDHWILCAQKLNQWDVLFDFSKQEGCAELYLECAWRLSDWSTE 2638
Query: 2765 REALEHSVKSVMDVPTPRRQIFETFLALQQFGETKKGDQEVRRLCDEGIQLSLKKWHSLP 2824
++ LE + KS+ + RR + L L + E R+ DE +Q SL++W LP
Sbjct: 2639 QDTLEKATKSLSPFTSLRRHTADALLYLNKTQRKMGSVTEFSRIIDECMQFSLRRWQQLP 2698
Query: 2825 KRYTPAHKALLHSFQQYMEFLEATQIYANLASTTVQNLDTKAQEIKRVLQAWRDRLPNIW 2884
KR +H +LLH FQ+ +E EA IY+ L T + N+D K ++IK VLQ WR+RLPN+W
Sbjct: 2699 KRVYQSHVSLLHHFQEIVELQEAFGIYSQLNDTNIHNIDNKLRDIKVVLQGWRERLPNVW 2758
Query: 2885 DDITIWDDLVTWRQHVFNVINSAYLPLVPALQQANSNSNINT--HAYRGYHEIAWVINRF 2942
DDI IW DL+ WRQ VF IN +LPLV QQ+ + SN N+ + YRGYHE+AW+INRF
Sbjct: 2759 DDIDIWSDLIAWRQSVFKSINKVFLPLVSIAQQSTNKSNTNSVSYLYRGYHELAWIINRF 2818
Query: 2943 AHVARRHNMPDVCISQLARIYTLPNIEIQEAFLKLREQAKCHYQNMNELTTGLDVISNTN 3002
AHVAR H++P+VCI+QL +IYTLPNIEIQEAFLKLREQA+CHY++ +E+ GL+VI+NTN
Sbjct: 2819 AHVARVHHLPEVCINQLTKIYTLPNIEIQEAFLKLREQAECHYESPSEMQLGLEVINNTN 2878
Query: 3003 LVYFGTVQKAEFFTLKGMFLSKLRAHDEANQAFATAVQIDLNLAKAWAQWGFFNDRRLSE 3062
L+YF QKAEFFTLKGMF ++L DEANQAFATAVQID+ KAW++WG ++D
Sbjct: 2879 LMYFRNRQKAEFFTLKGMFQNRLGEKDEANQAFATAVQIDIGSGKAWSEWGLYHDELFQA 2938
Query: 3063 EPKNISFASNAMSCYLQAAGLYKNSKTRKLLSRILWLLGRDDSSNSLAYAFDSFRGEIPV 3122
P+ I A NA+SC+LQA+ L +S ++ LL+R+LWLL DDS S++ SF+ EIP
Sbjct: 2939 NPQEIHHACNAVSCFLQASSLLSSSNSKPLLTRVLWLLSVDDSHGSVSEVVSSFKSEIPT 2998
Query: 3123 WYWITFIPQLLTALSHKEAFLVRKILIRIAKSYPQALHFQLRTTKEDFAVIQRQSLALAR 3182
W WI FIPQLL+ALSH+E+ R ILI+IAK+YPQ+LHFQLRT EDF ++++Q A
Sbjct: 2999 WNWIPFIPQLLSALSHRESIHARAILIQIAKTYPQSLHFQLRTAYEDFLMLKKQQAANV- 3057
Query: 3183 TQGEPAETENQENSKHPSPD-------------NSRTTSQNK--SQDQDMYPNNRQPWEY 3227
+G EN +S + S D NS+ S + S ++ + WE
Sbjct: 3058 LRGNSRLRENDSSSDNKSKDLSPSGSFSSVSQFNSKNGSPSSIDSSEKHQISTVKPAWEL 3117
Query: 3228 LEELNGILKTAYPLLALSLESLVDQINQKFKTNPDEDLFRLINVLLIDGTYNYNRLPYPR 3287
+ ++ ILKTAYPLLAL++E++VDQI+ + K+ P+ED +RLI LL DG +RL
Sbjct: 3118 IADVTSILKTAYPLLALTMETMVDQIHTRLKSFPEEDAYRLIVALLNDGLQYISRLGVVS 3177
Query: 3288 EKPPLPSSTEANLIRFSENLLPPNIRVKFNADFIESKPDFEVYIKRLRFWRNRLENKLDR 3347
+ ++AN+ RF+EN+LP ++R F DF+E+K D Y+ +LR WR + EN LD+
Sbjct: 3178 KNTFQLPMSQANIQRFAENVLPVSVREAFLRDFVETKLDLLTYVDKLRMWRKKFENILDQ 3237
Query: 3348 APKVESMEAICPNLSNFHHQKFEDIKVPGQYLLNKDNNTHFVKIGRFMPEVDFTRGTHTS 3407
PK +E LS F HQKF+++++PGQYLL+K+NN FV++ RF+P VD RG
Sbjct: 3238 RPKFLHLEQCSLYLSEFQHQKFDEVEIPGQYLLDKNNNNDFVRLERFVPNVDLVRGHTMC 3297
Query: 3408 HRRLTIRGHDGSLHSFAVQYPAVRHSRREERMFQLYRLLNERLRKNVQTRRRDIQFTVPI 3467
++RLT+RG+DG L+ FA+QYPA RHSRREERM QL N LR ++ + R+ F +P
Sbjct: 3298 YKRLTLRGYDGKLYPFALQYPATRHSRREERMLQLLGTFNTVLRSKIEIQNRNFSFQIPS 3357
Query: 3468 AVPLSPQVRVMSDSASFRTLHQIYDEFCAKKNMDRDAIQDFITEQL-------------- 3513
++PLS +R+++D S+ T+ I DE+C + M D F ++L
Sbjct: 3358 SIPLSSHMRIIADKPSYVTMQTISDEYCKNRGMPLDYGIRFYFDRLQTGLIQLKRASASM 3417
Query: 3514 ----NVAHDKVLPPPDITAVKVEIFSSIHSLFIPSTLLKDYYSKLFSEFEDFWLFRKQFA 3569
V K + +++++ +++S P ++ DY+ K F + DFW FR+ F
Sbjct: 3418 LSNSTVEEKKQIFRQRALQLRMQLLETLNSSVFPESIYYDYFYKTFERYCDFWFFRRTFT 3477
Query: 3570 SQYAAFVFMTFMLSINNRSPHKIFVDEKSGNVHTLEMLPSRYSYERVNQYAKQFETNLPN 3629
+QYA + MT++ +I RSP K+F+ + SG V + ++LPS + +
Sbjct: 3478 TQYAYMIIMTYVFNIGGRSPQKLFIVKDSGQVMSQDLLPS-----------------MTS 3520
Query: 3630 SAPVFHNNEPVPFRMTPNIQKLIGDSAMEGVFSVGLFVIARALLEPDHELNTYLSLFIRD 3689
+ PVFHN E VPFR+TP IQ LI D +EG+ S + IA++L P ++ YLSL++RD
Sbjct: 3521 NQPVFHNTEAVPFRLTPPIQYLISDLGVEGLLSGLVMSIAQSLSSPTTDIKQYLSLYVRD 3580
Query: 3690 EVISWYSSMNRSIVEDPHLYAIVLTNVDLIIRKVAQFGHMSSSPSVATQYVLDAISAAVS 3749
EV W + I + L+ V NV+L+ R+++ H Q ++D +S A +
Sbjct: 3581 EVFWWSKQQRKPIPQGIQLFETVKVNVELLFRRISVISHNVPEDLPLNQTLVDLVSQATN 3640
Query: 3750 PRNLAKCDQSFMAWL 3764
P+ LA+ DQ + AWL
Sbjct: 3641 PQQLAQMDQLWQAWL 3655
Score = 202 bits (513), Expect = 1e-50
Identities = 119/424 (28%), Positives = 228/424 (53%), Gaps = 15/424 (3%)
Query: 65 QISMNASSPEHKLRNTCLELLNRCPLNDKMEPMAMEVLQCLLKILTLENDENGVLCMKIL 124
++++ +S ++L+ L L+ C D+ + A + + ++ +N+E V C+K++
Sbjct: 63 EVNLYRNSSVNELKIEALTLIQSCAHRDEFKQYAQSCVLSFISLIKADNEEVAVFCLKVI 122
Query: 125 TSLFKCYKQPLESEVNTFIKIIVGIYENVPNLVASTFL----GEEETSSSTADSQDFSNS 180
+FK +K +ES F +++ + N+P L+ S F+ EE +++ A S
Sbjct: 123 MDIFKTFKFCIESTAQPFFDLVLELSTNLPYLIPSIFVENPKSNEEENTTLAFGSYLSTE 182
Query: 181 NNEEDAFENLSAPSKKHLEKATESFKTLSECPITMVTLFSSYKHLILVDLPTFLPLVIDL 240
+ N A S + LE A++SF+ ECP+ +V + +Y+ + +P + +
Sbjct: 183 TSIIQQRVNSLAISTQPLELASQSFRVYVECPVIIVLILQAYRQAAFPGVQAIIPCFLKM 242
Query: 241 LTLEVKQQQKSREELEAKGEKLIGMSSEIKNRSAFCDYVLAQIKATSFLAYVFIRGYATD 300
+ ++V S +E + I I+N+ + ++ +AQ+K SFLAY+ +R +
Sbjct: 243 VQIDVPIDIASYAMIEK--DSSIDFIEFIRNKYQYRNFFMAQVKTLSFLAYI-LRTHPNT 299
Query: 301 ILKLHVKKVPDLVMRLLQDCPSELSSARKELLHATRHILSTSYKKLFLPKINLMFDQKVL 360
+ + + +PD+V++LL+ CP ++ ARKELL ATRHILST+ K LF+ K++ + D +L
Sbjct: 300 LSEKDI--IPDIVIKLLRRCPFDMCFARKELLVATRHILSTNLKSLFVKKLDFLLDLNIL 357
Query: 361 IGDGFTSYETLRPLAYSTLADFIHNIRSDLAMADIEKTVKMYTSFLLDESLALTVQIMSA 420
+G+G + + LRPLA+STLAD +H++R +L I K++ +Y++ + D +L++ +Q M A
Sbjct: 358 LGNGVGTQKLLRPLAFSTLADLLHHVRDELNETQIRKSIMIYSTNMHDLTLSIGLQTMGA 417
Query: 421 KXXXXXXXXXXXXGKKDAYEVPKAKKLLMTIIEAYTSRFKLLNSQHKKILKQHNVYEQSK 480
+ +P A LL++I +++ ++F LN + K+ E+ K
Sbjct: 418 RLILNMVDRMISLP-----SIPDAIFLLLSIFDSFVNKFSELNDSLDQFFKK-KYEEEIK 471
Query: 481 NKKS 484
KS
Sbjct: 472 ETKS 475
>At2g17930 [TBLD] KOG0889 Histone acetyltransferase SAGA TRRAP/TRA1 component
PI-3 kinase superfamily
Length = 3795
Score = 1123 bits (2904), Expect = 0.0
Identities = 936/3490 (26%), Positives = 1583/3490 (44%), Gaps = 445/3490 (12%)
Query: 596 LKDAFYLYRTLLSFLKTIIHDLKVFN-PPPDEYTTMNP-KMWSALSRVFSYEEVIVLKNL 653
+ D L +TL+ +KTII + + P P + M ++W A VLK+
Sbjct: 428 VNDCKNLIKTLVMGMKTIIWSITHAHLPRPQGFKGMREDEVWKASG---------VLKSG 478
Query: 654 FHECIAGLHLFSSNPEGIDPSTVKAHFDITTPSLPVSATKDGRELMDYFAIIFMQIDSPV 713
H C+A LF E + + + + A + R+LMD F++ ++
Sbjct: 479 VH-CLA---LFKEKDEEKEMLNLFSQ---------ILAIMEPRDLMDMFSLCMPEL---- 521
Query: 714 FNEIVESEIVFIYESLLRDSALLHVAQSFLTSEITSPNFTGILLKFL-NSKLPELGNVDS 772
+ES++ ++ L+ + + L + F +L+ L +SKL L N DS
Sbjct: 522 ------------FESMINNNQLVQIFAALLQAPKVYKPFADVLINLLVSSKLDVLKNPDS 569
Query: 773 NKSNILIRLFKLSFMSVNLFPITNEAVLLPHLNNLILDSLKYSTEAEEPLVYFYLIRTLF 832
+ +++ LF+ F +V P E +L H+ ++ +K +TE E+PL Y L+RT+F
Sbjct: 570 AATKLVLHLFRCIFGAVTKTPSDFERILQHHVPVIMEVCMKNATEVEKPLGYMQLLRTVF 629
Query: 833 RSIGGGRFENLYRSIKPILQTLLQSLNKMIQTACRPHERDLYVELCLTVPVRLSVLAPYL 892
R + G ++E L R + P+L L L M++ +DL +ELCLT+P RLS L PYL
Sbjct: 630 RGLAGCKYELLLRDLIPMLLPCLNILLTMLEGPAGEDMKDLLLELCLTLPARLSSLLPYL 689
Query: 893 NYLMKPLVYALVGFPELITQGLRTLELCIDNLTPEYLDPILEPVVGDVMKALFDLLKPQP 952
LMKPLV+ L G EL++ GLRTLE +D+L P++L+P + V+ +V+ AL+ L+P P
Sbjct: 690 PRLMKPLVFCLRGSDELVSLGLRTLEFWVDSLNPDFLEPSMANVMSEVILALWSHLRPVP 749
Query: 953 FNHQISHTTVRILGKLGGRNRRFIETPKDL--KTETELNIEVDAWFNIYGFNSEVPLSIT 1010
+ ++ILGKLGGRNRRF++ P L K E + + F VPL
Sbjct: 750 YPW--GKKALQILGKLGGRNRRFLKEPLTLECKDNPEHGLRLVLTFEP-STPFLVPLDKF 806
Query: 1011 PGVNSASDILKDYRVNLFYRKSAYKYLSTVLMLLLG------SVGPIPKNLTECLQKGVK 1064
+ A+ I +++ ++++YRK A K+L L+ L VG P+ L+ L+ V
Sbjct: 807 INLAVAAVIQRNHGMDIYYRKQALKFLRVCLLSQLNLPGCVTDVGQTPRQLSTLLRSSVD 866
Query: 1065 LLNSEELEDNIQFN-DEKVVDPGKFNNXXXXXXXXXXCMFYAASIKELQEDVTVLVNKIV 1123
+S + ++ D V + + A+S +L + V I
Sbjct: 867 --SSWHRSEAVEIKADLGVKTKTQLMAEKSIFKTLLITILAASSDPDLSDTDDDFVENIC 924
Query: 1124 THFSL-LQVN---------------EALSEKRRQPHVFSVDVKQPDVSISCDILL----- 1162
HF++ L V+ +S R S ++KQ D I D L+
Sbjct: 925 RHFAIILHVDYTSSNASTSTSSLGGSVISTSSRSKSNQSSNLKQLDPLIFLDALVDVLAD 984
Query: 1163 ------KAIRNGLCSYLEDSRALA------IEAIKKVHDIGKVIYGDT---LYLEHSFIT 1207
KA N L + E LA + + H+ ++ + +Y H +
Sbjct: 985 ENRLHAKAALNALNVFAETLLFLARVKHADVLMARGGHNASMIVSSPSTNPVYSPHPSVR 1044
Query: 1208 T-----LMRTFIHQCYSETYYEKRAGMXXXXXXXXXXXXPVHYVKNFQYGLTSGLLFVLK 1262
L+ +H CY T+ + G+ V + FQ + GL++VLK
Sbjct: 1045 IPVFEQLLPRLLHGCYGSTWQAQMGGVMGLGALVGKVN--VETLCYFQVKIVRGLVYVLK 1102
Query: 1263 DTHAEAPLFITEDAKALLYEVIEVTCADVKEENLGDKHLQNSLTDIVCELSNPTEI--VR 1320
A E ++ L+ + V D K Q+ + + EL NP VR
Sbjct: 1103 RLPVYASKEQEETSQVLMQILRVVNNVDEANSEARRKSFQDVVEYLATELFNPNASIPVR 1162
Query: 1321 NVCQECLGKISTLTKIPVVTLMNHAKNFLLSPIFAKPLRALPFSMQIGNVDAVIYCLRLQ 1380
Q CL +++ T V L+ LL P+ +PLR+ Q+G V A+ +CL L+
Sbjct: 1163 KNVQNCLALLASRTGSEVTELLEPLYQLLLQPLIMRPLRSKTVDQQVGTVAALNFCLALR 1222
Query: 1381 NSFLKFDEELFRLLHESIALVDADDISLASTQRITEYQTSQQLIKLRVVCIRLLAQALLN 1440
LK EL L E++ + +AD+ A + TS L +LR CI LL +
Sbjct: 1223 PPLLKVTPELVNFLQEALQIAEADETVWAVKLMNPKVLTS--LNRLRTACIELLCTTMAW 1280
Query: 1441 PEFANAQNGSIRIKVLAVFFKTMLKPSPEIIEATYEGLKIVLAENSKLPKELLQNGLKPM 1500
+F + +R K++++FFK++ +PEI+ EGL+ V+ + ++PKELLQ+ L+P+
Sbjct: 1281 TDFRTQTHNELRAKIISMFFKSLTCRAPEIVAVAKEGLRQVINQQ-RMPKELLQSSLRPI 1339
Query: 1501 LMNLSDHQKLTVPGXXXXXXXXXXXIAYFKVEIGKKLSDHLDAWCQIEVLDTLFGKEITQ 1560
L+NL+ + L++P +F V +G KL +HL W + E L
Sbjct: 1340 LVNLAHTKNLSMPLLQGLARLLELLSNWFNVTLGGKLLEHLKKWLEPEKLAQSQKAWKAG 1399
Query: 1561 QTPTKIICSIFNIFHLLPPQAGIFLNELVFKLISLERKLR-----LQLDSPFRVPLAKYL 1615
+ P KI +I +FHLLP A FL+ELV I LE L +++SP+R+PL K+L
Sbjct: 1400 EEP-KIAAAIIELFHLLPHAASKFLDELVTLTIDLEAALPPGQVYSEINSPYRLPLTKFL 1458
Query: 1616 NRFHVQVLTYFKTNMRSRQLVLLMCSIIQKKEAPVLRKAFEPQLREFLKFYVEKIPENPV 1675
NR+ + YF + + + II+ LR+ ++ L + +I P
Sbjct: 1459 NRYAALAVDYFLSRLSEPKYFRRFMYIIRSDAGQPLREELAKSPQKILSYAFPEISPKPD 1518
Query: 1676 RVVSFFANSIDLVYVYHTSNEESWI---LENSDI---------------LFELKSMLTTV 1717
+S A++ +S +E+ I LE+S++ L+ +K+M+ +
Sbjct: 1519 PTLSTTASTPPAT----SSGDENHISVKLESSNVASTKANIASDAYFQGLYLIKTMVKLI 1574
Query: 1718 LKLINENSFNIDILQLN-------QSIEKFQMIYLAYLKQKKYDVPLFLEMIQYSYDNDL 1770
+ N D L L ++ Q + L +K+ K+ V FL +++
Sbjct: 1575 PSWLQSNRSVFDTLVLIWKSPARISRLQNEQELNLVQVKESKWLVKCFLNYLRHEKSEVN 1634
Query: 1771 KIPNEVNSFIFDDIISCVDVQLKRKYILECLQFSLREERSLKARNFVIKRVVNSIMIHES 1830
+ + ++ F+F I LK YI+E + + +F+ + +S +
Sbjct: 1635 VLFDILSIFLFHSRIDYTF--LKEFYIIEVAEGYPPNMKRALLLHFL--NLFHSKQLGHD 1690
Query: 1831 TTKNSVDELISPDNEIFAFLNQHIWNPKSSSVVLNTVIGKLDS-----------IRFELL 1879
++ LI P AF N W +V V LD +R ELL
Sbjct: 1691 HLVQAMQMLILP-MLAHAFQNGQTWEVIDPDIVKTIVERLLDPPEEVSAEYDEPLRIELL 1749
Query: 1880 QLTSILLKYAPTLLEPVKRDLIKFAWKFIKLEDIQLKQAAYVTTSLFISKFDLPVNIVTQ 1939
QL ++LLKY + L +++LIKF W +K ED KQ A+V F+ + P I+ Q
Sbjct: 1750 QLATLLLKYLQSDLVHHRKELIKFGWNHLKREDSASKQWAFVNVCHFLDAYQAPEKIILQ 1809
Query: 1940 VFVAILRVHQIEARFMVKESLDLLAPVVADRSK-GSEEPTTWVNWVRRVILESNFQQNTI 1998
VFVA+LR Q E + +VK++LD+L P + R G W+ + +++++E +
Sbjct: 1810 VFVALLRTCQPENKMLVKQALDILMPALPKRLPLGDSRMPIWIRYTKKILVEEGHSIPNL 1869
Query: 1999 LYQFL--ISQKDIFFPYKDMFIPNIISYIGRLTLLTNPSTENQTLTIDLCDLVMYWEKQT 2056
++ FL + D+F+ + F+P +++ + RL L N + EN+ L I+L LV+ WE+Q
Sbjct: 1870 IHIFLLVVRHSDLFYSCRAQFVPQMVNSLSRLGLPYNTTAENRRLAIELAGLVVSWERQR 1929
Query: 2057 -------------------FSAQSKDDPDVNMDGSE------------------------ 2073
S DP + DGS
Sbjct: 1930 QNEMKMVTDTDGTSQITDEMHTSSGADPKRSTDGSATSEDPSKRVKIEPGLQSICVMSPG 1989
Query: 2074 ------GIVTSSSTS---------LSQREAFAAFLIRFICVSNHRACET-PLGSKALSVL 2117
+ T S + + E FLIR V + ET + +AL +L
Sbjct: 1990 GASSIPNVETPGSATQPDEEFKPNAAMEEMIINFLIRVALVIEPKDRETNTMYKQALDLL 2049
Query: 2118 TELLSIGYLPEAVVKLSYFEKFLIQQDLESANLLYYCMNALDVLDIIFRTKDPKWIINNL 2177
++ L + P A VK +Y EK L ++ LDV++ + + +I NN+
Sbjct: 2050 SQALEVW--PSANVKFNYLEKLLSSMPPSQSDPSTALAQGLDVMNKVLEKQPHLFIRNNI 2107
Query: 2178 KTIQTLLDKCLHANHHDLQEALQKVLSTVLTAVKDDDVPFESEEDTDSKVFVNLVSSIIS 2237
I +L+ C D ++L +L V TA D + D K+ V+ +I+
Sbjct: 2108 NQISQILEPCFKHKMLDAGKSLCSLLKMVFTAFPLD----AANTPPDIKLLYQKVNELIN 2163
Query: 2238 ENLNGTTSVAAG-----------VILCWTLFVNIPSQIDVLLPLLMKTFNKLCKD----- 2281
+++N T+ V+L N+ V +L++ +L +D
Sbjct: 2164 KHVNTVTAPQTSGDDNSFGSISFVLLVIKTLANVHKNF-VDSYVLVRILQRLARDLGSAV 2222
Query: 2282 --HLTISQPKDA-TAVEDARITTKL------LKKVFYILSFKVSTLGDSRRPFLSTV-AL 2331
H Q D+ +AV +R T + +K V ++ V + D +R + L
Sbjct: 2223 GSHPRQGQRTDSDSAVTSSRQTADVGAVICNIKSVLELIDETVMLIADCKRSVTQILNTL 2282
Query: 2332 LIDRSMDQNFLQKIVLIAKNWVFTN----------EIFPTVKEKAAILTKMLAFEIRGEP 2381
L ++ D + L I+ + K WV + F T K+ L K+ + +
Sbjct: 2283 LSEKGTDASVLLCILDMIKRWVEDDFSKTGASGLSGSFLTQKDVLTFLNKLSYID---KQ 2339
Query: 2382 HLSKQFYEI----ILQLF-----ENKKYN---NSEITVRMEQPFLVGTRISDIKLRSKLM 2429
H S + E LQL ++ KY E+++++E+ F++G R S +R K
Sbjct: 2340 HFSSEALEEWDQKYLQLLYGLCADSTKYPLGLRQEVSLKVERHFMLGLRASHPGMRRKFF 2399
Query: 2430 NILNGSLDNDIKERLYYVVRDQNWEFVADYMWLSQACQLLFGACVMEHRIKLTEH----F 2485
+ + SL + RL Y+++ Q+WE ++D WL Q LL V + I L +
Sbjct: 2400 LLYHESLGKTLFARLQYIIQIQDWEALSDVFWLKQGLDLLLAILVEDKPISLAPNSARVL 2459
Query: 2486 PLSPLS--AIERNIIVEDEDKVITNSALESLIREHQSFIDKINSIKCCDIINPLVDIFYQ 2543
PL P I+ E S +S++ +H F+ + ++ D++ PL ++ +
Sbjct: 2460 PLLPSDNPGIQHQAPANLEGPEEVTSMFDSIVMKHAQFLSATSKLQVADVVIPLRELAHT 2519
Query: 2544 SPEAVRATWVNVFPVAYKSIPRNEKYGFVRSLVALLSKDYHTKQASIHVNVISTMLESVS 2603
WV VFP+ + ++ + E+ + +++LLSKDYH KQ NV+ +LE +
Sbjct: 2520 DANVAYHLWVLVFPIVWVTLLKEEQVALAKPMISLLSKDYHKKQQGHRPNVVQALLEGLQ 2579
Query: 2604 KIESL-ELPPHLVRYLGITFNAWYQSIDLLEQIQETSNIDNSKILDTNEDALLELYSSIQ 2662
+P L++Y+G T+NAW+ ++ LLE +++SK ++ L ELY +
Sbjct: 2580 LSHPQPRMPSELIKYIGKTYNAWHLALALLES-HVMLFMNDSKCAES----LAELYRLLN 2634
Query: 2663 EDDMFYGLWRRKAKYTESSIALSYEQIGLWDKAQQMYEAAQVKARGGFLPYS--ESEYEL 2720
E+DM +GLW++++ E+ LS Q G W +AQ ++ A VKA G + ++E L
Sbjct: 2635 EEDMRFGLWKKRSITAETRAGLSLVQHGFWQRAQSLFYQAMVKATQGTYNNTVPKAEMCL 2694
Query: 2721 WEDNWILCASKLQHWDILTELAKHEGFTDLLLECGWRVAEWNADREALEHSVKSVMDVPT 2780
WE+ W+ CAS+L WD L + K ++LL+ W++ +W ++ H + T
Sbjct: 2695 WEEQWLHCASQLSQWDALVDFGKSIENYEILLDSLWKLPDWAYLKD---HVIPKAQVEET 2751
Query: 2781 PRRQIFETFLALQQFGETKKGDQEVRRLCDEGIQLSLKKWHSLPKRYTPAHKALLHSFQQ 2840
P+ ++ +++ AL GD E +G+ L+L++W LP+ A LL FQQ
Sbjct: 2752 PKLRLVQSYFALHDRNSNGVGDAE--NTVGKGVDLALEQWWQLPEMSVHARVPLLQQFQQ 2809
Query: 2841 YMEFLEATQIYANLAS-------TTVQNLDTKAQEIKRVLQAWRDRLPNIWDDITIWDDL 2893
+E E+ +I+ ++A+ T V L + ++K +L+ WR R PN WD++T+W D+
Sbjct: 2810 LVEVQESARIHVDIANGNKVSGNTAVGGLGNRYADLKDILETWRLRTPNEWDNMTVWYDM 2869
Query: 2894 VTWRQHVFNVINSAYLPLVPALQQANSNSNINTHAYRGYHEIAWVINRFAHVARRHNMPD 2953
+ WR ++NV+ A+ A SNS ++ + G+ + AW +N+ A +AR+ + D
Sbjct: 2870 LQWRNEMYNVVIDAFKDF------ATSNSPLH---HLGFRDKAWNVNKLARIARKQGLYD 2920
Query: 2954 VCISQLARIYTLPNIEIQEAFLKLREQAKCHYQNMNELTTGLDVISNTNLVYFGTVQKAE 3013
VC+ L ++Y +E+QEAF+K+REQAK + + E +GL++I++TNL YF KAE
Sbjct: 2921 VCVQILEKMYGHSTMEVQEAFVKIREQAKAYLEMKGERASGLNLINSTNLEYFPDKIKAE 2980
Query: 3014 FFTLKGMFLSKLRAHDEANQAFATAVQIDLNLAKAWAQWGFFNDRRLSEEPKNISFASNA 3073
F LKG F KL + AN A++ A+ + NL K W WG + D E + I + A
Sbjct: 2981 IFRLKGDFHLKLNDTESANIAYSNAITLFKNLPKGWISWGSYCDMAYQETQEEI-WLEYA 3039
Query: 3074 MSCYLQAAGLYKNSKTRKLLSRILWLLGRDDSSNSLAYAFDSFRGEIPVWYWITFIPQLL 3133
+SC+LQ + S +R ++R+L+LL D ++ + FD ++P W W+++IPQLL
Sbjct: 3040 VSCFLQGI-RFGVSNSRSHIARVLYLLSFDTANEPVGKVFDKHLDQVPHWVWLSWIPQLL 3098
Query: 3134 TALSHKEAFLVRKILIRIAKSYPQALHFQLRT---TKED-----------FAVIQRQSLA 3179
+L EA + +L++IA +PQAL++ LRT + D A +Q+
Sbjct: 3099 LSLQRTEAPHCKLVLLKIAAVFPQALYYWLRTYLLERRDAVNKSELGRLVLAQRMQQNAT 3158
Query: 3180 LARTQGEPAETENQ---------ENSKHPSPDNSRTTSQNKSQDQDMYPNNRQP------ 3224
A G +ENQ H S + S+ + + +++P + QP
Sbjct: 3159 GAGHGGSNLPSENQIHQGAQTSGAGGTHDSGNPHGQESERSTTENNLHPGSDQPMHQSSS 3218
Query: 3225 ------------------------WEYLEELNGILKTAYPLLALSLESLVDQINQKFKTN 3260
++ +++ L+ + LA LE L+ +I +F T
Sbjct: 3219 AINDNNENTVRRNGASLAISAAGAFDAAKDIMEALRGKHNNLASELEVLLTEIGSRFVTL 3278
Query: 3261 PDEDLFRLINVLLIDGTYNYNRLPYPREKPPLPSSTEANLIRFSENLLPPNIRVKFNADF 3320
P+E L ++N LL Y Y P++T A + + + L R F+AD
Sbjct: 3279 PEERLLAVVNALL-HRCYKY------------PTATTAEVPQPLKKELSGVCRACFSADA 3325
Query: 3321 I--------ESKPDFEVYI----------------KRLRFWRNRLENKL-DRAPKVESME 3355
+ E K DFE ++ RL+ W+N L++ + DR P V +E
Sbjct: 3326 VTKHVEFVKEYKQDFERHLDPESTTTFPATLAELTARLKKWKNILQSNVEDRFPAVLRLE 3385
Query: 3356 AICPNLSNFHHQKFEDIKVPGQYLLNKD-NNTHFVKIGRFMPEVDFTRGTHTSHRRLTIR 3414
L +F+ D+++PGQY +++ H VK+ R +V R +S RRLT+
Sbjct: 3386 DESRVLRDFN---VVDVEIPGQYFADQEVAPDHTVKLDRVGADVPIVRRHGSSFRRLTLI 3442
Query: 3415 GHDGSLHSFAVQYPAVRHSRREERMFQLYRLLNERLRKNVQTRRRDIQFTVPIAVPLSPQ 3474
G DGS F VQ ++R +ER+ QL+R++N+ K+ ++RRR I PI +P+ Q
Sbjct: 3443 GSDGSQKHFIVQTSLTPNARSDERILQLFRVMNQMFDKHKESRRRHIGIHTPIIIPVWSQ 3502
Query: 3475 VRVMSDSASFRTLHQIYDEFCAKKNMDRDAIQDFITEQLNVAHDKVLPPPDITAVKVEIF 3534
VR++ D + T ++Y+ CA+ + + D EQLN A + I ++++ +
Sbjct: 3503 VRMVEDDLMYNTFLEVYENHCARNDREADLPITHFKEQLNQAISGQISAEAIGDLRLQAY 3562
Query: 3535 SSIHSLFIPSTLLKDYYSKLFSEFEDFWLFRKQFASQYAAFVFMTFMLSINNRSPHKIFV 3594
I + ++ Y K W F+KQFA Q A FM+FML I RSP+K+
Sbjct: 3563 IDITKTLVNDSIFSQYMYKTLMSGSHMWAFKKQFAVQLAVSSFMSFMLQIGGRSPNKVLF 3622
Query: 3595 DEKSGNVHTLEMLPSRYSYERVNQYAKQFETNLPNSAPVFHNNEPVPFRMTPNIQKLIGD 3654
+ +G + + P+ ++ N + NEPVPFR+T N+Q
Sbjct: 3623 AKNTGKMFQTDFHPA-------------YDAN-----GMIEFNEPVPFRLTRNMQAFFSQ 3664
Query: 3655 SAMEGVFSVGLFVIARALL--EPDHELNTYLSLFIRDEVISWYSSMNRSIVEDP------ 3706
+EG+ + A+A++ + + L L++F RDE++SW+ + P
Sbjct: 3665 FGVEGLLMSSMCSAAQAVISSKQNEHLRYQLAMFFRDELLSWFGRRPLGVPIPPVGGIAT 3724
Query: 3707 ----HLYAIVLTNVDLIIRKVAQFGHMSSS---------PSVATQYVLDAISAAVSPRNL 3753
L V NV+ +I+++ S P + V + + AA+SPRNL
Sbjct: 3725 LNPAELKHKVNANVEDVIKRIRGIAPQYFSEEDENTVEPPQSVQRGVNELVEAALSPRNL 3784
Query: 3754 AKCDQSFMAW 3763
D ++ W
Sbjct: 3785 CMMDPTWHPW 3794
Score = 97.1 bits (240), Expect = 5e-19
Identities = 52/203 (25%), Positives = 106/203 (51%), Gaps = 8/203 (3%)
Query: 72 SPEHKLRNTCLELLNRCPLNDKMEPMAMEVLQCLLKILTLENDENGVLCMKILTSLFKCY 131
+PEHKLRN +E+LNR P ++ + P ++L+ +++LT +N+ENG++C++I+ L + +
Sbjct: 69 NPEHKLRNIVVEILNRLPHSEVLRPFVQDLLKVAMQVLTADNEENGLICIRIIFDLLRNF 128
Query: 132 KQPLESEVNTFIKIIVGIYENVPNLVASTFLGEEETSSSTADSQDFSNSNNEEDAFENLS 191
+ LE+EV F+ + IY V+ F + + + + + +
Sbjct: 129 RPTLENEVQPFLDFVCKIYSIFRFTVSHFF-----DNVKMEEVKPMEMPTSSDQSLTPTP 183
Query: 192 APSKKHLEKATESFKTLSECPITMVTLFSSYKHLILVDLPTFLPLVIDLLTLEVKQQQKS 251
L +T SFK ++E P+ ++ LF Y L+ ++P LPL++ +++ + S
Sbjct: 184 PIGNVQLNPSTRSFKIITESPLVVMFLFQLYSRLVQTNIPHLLPLMVAAISVPGPENVPS 243
Query: 252 R---EELEAKGEKLIGMSSEIKN 271
+ +E KG ++ + +K+
Sbjct: 244 HLKPQFIELKGAQVKELLVSLKH 266
Score = 91.3 bits (225), Expect = 3e-17
Identities = 49/164 (29%), Positives = 93/164 (55%), Gaps = 2/164 (1%)
Query: 323 ELSSAR-KELLHATRHILSTSYKKLFLPKINLMFDQKVLIGDGFTSYETLRPLAYSTLAD 381
EL A+ KELL + +H+L T +K+ P I+ + D++VL+G G +E+LRPLAYS LA+
Sbjct: 251 ELKGAQVKELLVSLKHVLGTDFKRGLFPLIDTLLDERVLVGTGRACFESLRPLAYSLLAE 310
Query: 382 FIHNIRSDLAMADIEKTVKMYTSFLLDESLALTVQIMSAKXXXXXXXXXXXXGKKDAYEV 441
+H++R DL++A + + + +++ + D +L+L++ A+ G D +
Sbjct: 311 IVHHVRGDLSLAQLSRIIYLFSRNMHDSTLSLSIHTTCARLMLNLVEPIFEKG-VDQQSM 369
Query: 442 PKAKKLLMTIIEAYTSRFKLLNSQHKKILKQHNVYEQSKNKKSK 485
+A+ LL I++A+ +F ++L++ V + +SK
Sbjct: 370 DEARILLGRILDAFVGKFSTFKRTIPQLLEEGEVGKDRVTLRSK 413
>Hs4507691 [TBLD] KOG0889 Histone acetyltransferase SAGA TRRAP/TRA1 component
PI-3 kinase superfamily
Length = 3830
Score = 1089 bits (2816), Expect = 0.0
Identities = 858/3304 (25%), Positives = 1513/3304 (44%), Gaps = 331/3304 (10%)
Query: 693 KDGRELMDYFAIIFMQIDSPVFNEIVESEIVFIYESLLRDSALLHVAQSFLTSEITSPNF 752
K+ +E++++FA +F ++ F EI ++ + ++ E + ++ AL VA SFL + TS F
Sbjct: 626 KEEKEVLEHFAGVFTMMNPLTFKEIFQTTVPYMVERISKNYALQIVANSFLANPTTSALF 685
Query: 753 TGILLKFLNSKLPELGNVDSNKSNILIRLFKLSFMSVNLFPITNEAVLLPHLNNLILDSL 812
IL+++L +LPE+G+ + SN+ ++LFKL F SV+LF NE +L PHL+ ++ S+
Sbjct: 686 ATILVEYLLDRLPEMGS-NVELSNLYLKLFKLVFGSVSLFAAENEQMLKPHLHKIVNSSM 744
Query: 813 KYSTEAEEPLVYFYLIRTLFRSIGGGRFENLYRSIKPILQTLLQSLNKMIQTACRPHERD 872
+ + A+EP YF L+R LFRSIGGG + LY+ P+L LLQ LN + + H +D
Sbjct: 745 ELAQTAKEPYNYFLLLRALFRSIGGGSHDLLYQEFLPLLPNLLQGLNMLQSGLHKQHMKD 804
Query: 873 LYVELCLTVPVRLSVLAPYLNYLMKPLVYALVGFPELITQGLRTLELCIDNLTPEYLDPI 932
L+VELCLTVPVRLS L PYL LM PLV AL G L++QGLRTLELC+DNL P++L
Sbjct: 805 LFVELCLTVPVRLSSLLPYLPMLMDPLVSALNGSQTLVSQGLRTLELCVDNLQPDFLYDH 864
Query: 933 LEPVVGDVMKALFDLLKPQPFNHQISHTTVRILGKLGGRNRRFIETPKDLK---TETELN 989
++PV ++M+AL+ L+ ISH R+LGK GG NR+ ++ + L TE +
Sbjct: 865 IQPVRAELMQALWRTLRNPA--DSISHVAYRVLGKFGGSNRKMLKESQKLHYVVTEVQ-G 921
Query: 990 IEVDAWFNIYGFNSEVPLSITPGVNSASDILKDYRVNLFYRKSAYKYLSTVLMLLLGSVG 1049
+ F+ + ++P+ + +A D LK +YR+ A++ + L+ ++
Sbjct: 922 PSITVEFSDCKASLQLPME--KAIETALDCLKSANTEPYYRRQAWEVIKCFLVAMMS--- 976
Query: 1050 PIPKNLTECLQKGVKLLNSEELEDNIQFNDEKVVDPGKFNNXXXXXXXXXXCMFYAASIK 1109
+ N Q +E+ N+ + F +A IK
Sbjct: 977 -LEDNKHALYQLLAHPNFTEKTIPNVIISHRYKAQDTPARKTFEQALTGA---FMSAVIK 1032
Query: 1110 ELQEDVTVLVNKIVTHFSLLQVNEALS-------EKRRQPHVFSVDVKQPDVSISCDILL 1162
+L+ V ++ H++++ V + + QP ++ + + S D L+
Sbjct: 1033 DLRPSALPFVASLIRHYTMVAVAQQCGPFLLPCYQVGSQPST-AMFHSEENGSKGMDPLV 1091
Query: 1163 KAIRNGLCSYLEDSRALAIE--AIKKVHDIGKVIYGDT-LYLEHSFITTLMRTFIHQCYS 1219
+C E+ I A+ + D+ +I G + + ++ CY
Sbjct: 1092 LIDAIAICMAYEEKELCKIGEVALAVIFDVASIILGSKERACQLPLFSYIVERLCACCYE 1151
Query: 1220 ETYYEKRAGMXXXXXXXXXXXXPVHYVKNFQYGLTSGLLFVLKDTHAEAPLFITEDAKAL 1279
+ +Y K G+ P+ +V Q LLFV+ D E AK
Sbjct: 1152 QAWYAKLGGVVSIKFLMERL--PLTWVLQNQQTFLKALLFVMMDLTGEVSNGAVAMAKTT 1209
Query: 1280 LYEVIEVTCADVKEENLGD-------KHLQNSLTDIVCELSNPTEIVRNVCQECLGKIST 1332
L +++ +K+E + K + D+V E+++P VR L ++
Sbjct: 1210 LEQLLMRCATPLKDEERAEEIVAAQEKSFHHVTHDLVREVTSPNSTVRKQAMHSLQVLAQ 1269
Query: 1333 LTKIPVVTLMNHAKNFLLSPIFAKP--LRALPFSMQIGNVDAVIYCLRLQNSFLKFDEEL 1390
+T V +M K L + K LR P + QIG ++ +C LQ D +
Sbjct: 1270 VTGKSVTVIMEPHKEVLQDMVPPKKHLLRHQPANAQIGLMEGNTFCTTLQPRLFTMDLNV 1329
Query: 1391 FR---LLHESIALVDADDISLASTQRITEYQTSQQLIKLRVVCIRLLAQALLNPEFANAQ 1447
E + L +A+D +L ++ Y++ L+ LR+ + LA P+
Sbjct: 1330 VEHKVFYTELLNLCEAEDSALT---KLPCYKSLPSLVPLRIAALNALAACNYLPQS---- 1382
Query: 1448 NGSIRIKVLAVFFKTMLKPSPEIIEATYEGLKIVLAENSKLPKELLQNGLKPMLMNLSDH 1507
R K++A FK + + E+ EA ++ L E + + + + ++P+LM L D+
Sbjct: 1383 ----REKIIAALFKALNSTNSELQEAGEACMRKFL-EGATIEVDQIHTHMRPLLMMLGDY 1437
Query: 1508 QKLTVPGXXXXXXXXXXXIAYFKVEIGKKLSDHLDAWCQIEVLDTLFGKEITQQTPTKII 1567
+ LT+ F + ++ HL W ++ V+ T G + + KI
Sbjct: 1438 RSLTLNVVNRLTSVTRLFPNSFNDKFCDQMMQHLRKWMEVVVI-THKGGQRSDGNEMKIC 1496
Query: 1568 CSIFNIFHLLPPQAGIFLNELVFKLISLERKLRLQLDSPFRVPLAKYLNRFHVQVLTYF- 1626
+I N+FHL+P + L+ ++ ER + ++ SPFR PL K+L R Q + F
Sbjct: 1497 SAIINLFHLIPAAPQTLVKPLLEVVMKTERAMLIEAGSPFREPLIKFLTRHPSQTVELFM 1556
Query: 1627 -KTNMRSRQLVLLMCSIIQKKEAPVLRKAFEPQLREFLKFYVEKIPENPVRVVSFFANSI 1685
+ + Q + S ++ K+A LR F+ + + VR S +++
Sbjct: 1557 MEATLNDPQWSRMFMSFLKHKDARPLRDVLAANPNRFITLLLPGGAQTAVRPGSPSTSTM 1616
Query: 1686 DLVYVYHT--------SNEESWILENSDILFELKSMLTTVLKLINENSFNIDILQLNQSI 1737
L + N++SW+ ++ +L+ + V + E ++ N
Sbjct: 1617 RLDLQFQAIKIISIIVKNDDSWLASQHSLVSQLRRVW--VSENFQERHRKENMAATNWKE 1674
Query: 1738 EKF-QMIYLAYLKQKKYDVPLFLEMIQYSYDNDLKIPNEVNSFIFDDIISCVDVQLKRKY 1796
K L Y K+ D+ L ++++ L + ++ ++I + KR
Sbjct: 1675 PKLLAYCLLNYCKRNYGDIELLFQLLRAFTGRFLCNMTFLKEYMEEEIPKNYSIAQKRAL 1734
Query: 1797 ILECLQFSLRE-ERSLKARNFVIKRVVNSIMIHESTTKNSVDELISPDNEIFAFLNQHIW 1855
+ F+ LKA+ V++ ++N ++ S K ++L+ P N
Sbjct: 1735 FFRFVDFNDPNFGDELKAK--VLQHILNPAFLY-SFEKGEGEQLLGPPNPEGD------- 1784
Query: 1856 NPKSSSVVLNTVI-------GKLDSIRFELLQLTSILLKYAPTLLEPVKRD-------LI 1901
NP+S + V T + LDS+R LLQ ++L+++AP + ++ L+
Sbjct: 1785 NPESITSVFITKVLDPEKQADMLDSLRIYLLQYATLLVEHAPHHIHDNNKNRNSKLRRLM 1844
Query: 1902 KFAWKFIKLE---DIQLKQAAYVTTSLFISKFDLPVNIVTQVFVAILRVHQIEARFMVKE 1958
FAW + + D K + ++ + I+KF + IV QVF ++L+ H +EAR +V++
Sbjct: 1845 TFAWPCLLSKACVDPACKYSGHLLLAHIIAKFAIHKKIVLQVFHSLLKAHAMEARAIVRQ 1904
Query: 1959 SLDLLAPVVADRSKGSEEPTTWVNWVRRVILESNFQQNTILY--QFLISQKDIFFPYKDM 2016
++ +L P V R + + T +W R++I+E +++ ++ +++P +
Sbjct: 1905 AMAILTPAVPARMEDGHQMLT--HWTRKIIVEEGHTVPQLVHILHLIVQHFKVYYPVRHH 1962
Query: 2017 FIPNIISYIGRLTLLTNPSTENQTLTIDLCDLVMYWEKQTFSAQSKD---DPDVNMDGSE 2073
+ +++S + RL + + E + L +DL ++V+ WE Q Q D DP+ + +G
Sbjct: 1963 LVQHMVSAMQRLGFTPSVTIEQRRLAVDLSEVVIKWELQRIKDQQPDSDMDPNSSGEGVN 2022
Query: 2074 GIVTSSSTSLS-----------------------------------------QREAFAAF 2092
+ +S LS + F
Sbjct: 2023 SVSSSIKRGLSVDSAQEVKRFRTATGAISAVFGRSQSLPGADSLLAKPIDKQHTDTVVNF 2082
Query: 2093 LIRFICV--SNHRACETP---LGSKALSVLTELLSIGYLPEAVVKLSYFEKFLIQQDLES 2147
LIR C N +P L + +++L L P++ +KL +F+K L+ +E
Sbjct: 2083 LIRVACQVNDNTNTAGSPGEVLSRRCVNLLKTALRPDMWPKSELKLQWFDKLLMT--VEQ 2140
Query: 2148 ANLLYY--CMNALDVLDIIFRTKDPKWIINNLKTIQTLLDKCLHANHHDLQEALQKVLST 2205
N + Y L+VL + I+++ K +Q + C+ + + A+ +LS
Sbjct: 2141 PNQVNYGNICTGLEVLSFLLTVLQSPAILSSFKPLQRGIAACMTCGNTKVLRAVHSLLSR 2200
Query: 2206 VLTAVKDDDVPFESEEDTDS--------KVFVNLVSSIISENL-------NGTTSVAAGV 2250
+++ F +E T S + V +I E L N S G
Sbjct: 2201 LMSI-------FPTEPSTSSVASKYEELECLYAAVGKVIYEGLTNYEKATNANPSQLFGT 2253
Query: 2251 ILCW-TLFVNIPSQIDVLLPLLMKTFNKLCKDHLTISQPKDATAVEDARITTKLLKKVFY 2309
++ + N PS ID L+ + M++ K+ ++HL +T T++L+
Sbjct: 2254 LMILKSACSNNPSYIDRLISVFMRSLQKMVREHLNPQAASGSTEATSG--TSELVMLSLE 2311
Query: 2310 ILSFKVSTLG-DSRRPFLSTVAL-LIDRSMDQNFLQKIVLIAKNWVFTNEIF-----PTV 2362
++ +++ + + R+ F+ + LI++S D L+ +V I + WV N PT+
Sbjct: 2312 LVKTRLAVMSMEMRKNFIQAILTSLIEKSPDAKILRAVVKIVEEWVKNNSPMAANQTPTL 2371
Query: 2363 KEKAAILTKMLAFEIRGEPH---LSKQFYEIILQLFENKKYNNSEITVRMEQPFLVGTRI 2419
+EK+ +L KM+ + + P L+ QF +++ ++ ++ + SE+T ++E FL G R
Sbjct: 2372 REKSILLVKMMTYIEKRFPEDLELNAQFLDLVNYVYRDETLSGSELTAKLEPAFLSGLRC 2431
Query: 2420 SDIKLRSKLMNILNGSLDNDIKERLYYVVRDQNWEFVADYMWLSQACQLLFGACVMEHRI 2479
+ +R+K + + S+ + ERL YV QNWE + ++ W+ Q +LL C I
Sbjct: 2432 AQPLIRAKFFEVFDNSMKRRVYERLLYVTCSQNWEAMGNHFWIKQCIELLLAVCEKSTPI 2491
Query: 2480 ---------------------------KLTEHFPLSPLSA---------IERNIIVEDED 2503
+ H P +E +I + D
Sbjct: 2492 GTSCQGAMLPSITNVINLADSHDRAAFAMVTHVKQEPRERENSESKEEDVEIDIELAPGD 2551
Query: 2504 KVIT-----------NSALESLIREHQSFIDKINSIKCCDIINPLVDIFYQSPEAVRATW 2552
+ T + L L H F+D + +K +++ V + + S TW
Sbjct: 2552 QTSTPKTKELSEKDIGNQLHMLTNRHDKFLDTLREVKTGALLSAFVQLCHISTTLAEKTW 2611
Query: 2553 VNVFPVAYKSIPRNEKYGFVRSLVALLSKDYHTKQASIHVNVISTMLESVSK-IESLELP 2611
V +FP +K + +++ + L H Q + ++ +E++S+ + + +
Sbjct: 2612 VQLFPRLWKILSDRQQHALAGEISPFLCSGSHQVQRDCQPSALNCFVEAMSQCVPPIPIR 2671
Query: 2612 PHLVRYLGITFNAWYQSIDLLE----------QI---QETSNIDNSKILDTNE---DALL 2655
P +++YLG T N W++S +LE QI Q T + I + D+L
Sbjct: 2672 PCVLKYLGKTHNLWFRSTLMLEHQAFEKGLSLQIKPKQTTEFYEQESITPPQQEILDSLA 2731
Query: 2656 ELYSSIQEDDMFYGLWRRKAKYTESSIALSYEQIGLWDKAQQMYEAAQVKA-----RGGF 2710
ELYS +QE+DM+ GLW+++ KY+E++ A++YEQ G +++AQ+ YE A KA R
Sbjct: 2732 ELYSLLQEEDMWAGLWQKRCKYSETATAIAYEQHGFFEQAQESYEKAMDKAKKEHERSNA 2791
Query: 2711 LPYSESEYELWEDNWILCASKLQHWDILTELAKHEGFTD--LLLECGWRVAEWNADREAL 2768
P EY+LWED+WI C+ +L W+ LTE + +G + L+LEC WRV+ W A +EAL
Sbjct: 2792 SPAIFPEYQLWEDHWIRCSKELNQWEALTEYGQSKGHINPYLVLECAWRVSNWTAMKEAL 2851
Query: 2769 EHSVKSVMDVPTPRRQIFETFLALQQFGETKKGDQEVRRLCDEGIQLSLKKWHSLPKRYT 2828
S + ++ +LA+ E + + RL + L++++W LP +
Sbjct: 2852 VQVEVSCPKEMAWKVNMYRGYLAICHPEEQQLSF--IERLVEMASSLAIREWRRLPHVVS 2909
Query: 2829 PAHKALLHSFQQYMEFLEATQIYANLASTTVQNLDTKAQEIKRVLQAWRDRLPNIWDDIT 2888
H LL + QQ +E EA QI A L T + + ++K V++ WR+RLP + DD++
Sbjct: 2910 HVHTPLLQAAQQIIELQEAAQINAGLQPTNLGR-NNSLHDMKTVVKTWRNRLPIVSDDLS 2968
Query: 2889 IWDDLVTWRQHVFNVINSAYLPLVPALQQANSNSNINTHAYRGYHEIAWVINRFAHVARR 2948
W + WRQH + I +AY + ++ + + +A G H A I ++ +AR+
Sbjct: 2969 HWSSIFMWRQHHYQAIVTAY-------ENSSQHDPSSNNAMLGVHASASAIIQYGKIARK 3021
Query: 2949 HNMPDVCISQLARIYTLPNIEIQEAFLKLREQAKCHYQ-----NMNELTTGLDVISNTNL 3003
+ +V + L+RI+T+P + I + F K+R+Q KC+ Q NE GL+VI +TNL
Sbjct: 3022 QGLVNVALDILSRIHTIPTVPIVDCFQKIRQQVKCYLQLAGVMGKNECMQGLEVIESTNL 3081
Query: 3004 VYFGTVQKAEFFTLKGMFLSKLRAHDEANQAFATAVQIDLNLAKAWAQWGFFNDRRLSEE 3063
YF AEF+ LKGMFL+++ +EAN+AF+ AVQ+ L KAWA WG + + +E
Sbjct: 3082 KYFTKEMTAEFYALKGMFLAQINKSEEANKAFSAAVQMHDVLVKAWAMWGDYLENIFVKE 3141
Query: 3064 PKNISFASNAMSCYLQAAGLYKNSKTRKLLSRILWLLGRDDSSNSLAYAFDSFRGEIPVW 3123
+ + +A++CYL A SK+RK L+++LWLL DD N+LA A D + +P
Sbjct: 3142 -RQLHLGVSAITCYLHACRHQNESKSRKYLAKVLWLLSFDDDKNTLADAVDKYCIGVPPI 3200
Query: 3124 YWITFIPQLLTALSHKEAFLVRKILIRIAKSYPQALHFQLRTTKEDFAVIQRQ------- 3176
W+ +IPQLLT L E L+ ++ ++ + YPQA++F +RT + QR+
Sbjct: 3201 QWLAWIPQLLTCLVGSEGKLLLNLISQVGRVYPQAVYFPIRTLYLTLKIEQRERYKSDPG 3260
Query: 3177 SLALARTQGEPAETENQENSKHPSPDNSRTTSQNKSQDQDMYPNNRQPWEYLEELNGILK 3236
+ + + + HP + +S DQ ++ E L +L L
Sbjct: 3261 PIRATAPMWRCSRIMHMQRELHP----TLLSSLEGIVDQMVWFRENWHEEVLRQLQQGLA 3316
Query: 3237 TAYPLLALSLESLVDQINQKFKTNPDEDLFRLINVLLIDGTYNYNRLPYPREKPPLPSST 3296
Y + ++ D N + L V L + N + + L
Sbjct: 3317 KCYSVAFEKSGAVSDAKITPHTLNFVKKLVSTFGVGL-ENVSNVSTMFSSAASESLARRA 3375
Query: 3297 EANLIRFSENLLPPNIRVKFNADFIESKP---DFEVYIKRLRFWRNRLENKLDRAPKVES 3353
+A +++ + ++ +F DF S P I +L+ W LE K + PK
Sbjct: 3376 QAT----AQDPVFQKLKGQFTTDFDFSVPGSMKLHNLISKLKKWIKILEAKTKQLPKFFL 3431
Query: 3354 MEAICPNLSNFHHQKFEDIKVPGQYLLNKDNNTHFVKIGRFMPEVDFTRGTHTSHRRLTI 3413
+E C LSNF Q E +++PG++L+ K + +++KI RFMP V+ + +T+ RRL I
Sbjct: 3432 IEEKCRFLSNFSAQTAE-VEIPGEFLMPKPTH-YYIKIARFMPRVEIVQKHNTAARRLYI 3489
Query: 3414 RGHDGSLHSFAVQYPA-VRHSRREERMFQLYRLLNERLRKNVQTRRRDIQFTVPIAVPLS 3472
RGH+G ++ + V A + SRREER+ QL RLLN L K +T +R + FTVP V +S
Sbjct: 3490 RGHNGKIYPYLVMNDACLTESRREERVLQLLRLLNPCLEKRKETTKRHLFFTVPRVVAVS 3549
Query: 3473 PQVRVMSDSASFRTLHQIYDEFCAKKNMDRDAIQDFITEQLNVAHDKVLPPPDITAVKVE 3532
PQ+R++ D+ S +L +IY + CAKK ++ D ++L + V +
Sbjct: 3550 PQMRLVEDNPSSLSLVEIYKQRCAKKGIEHDNPISRYYDRLATVQARGTQASH--QVLRD 3607
Query: 3533 IFSSIHSLFIPSTLLKDYYSKLFSEFEDFWLFRKQFASQYAAFVFMTFMLSINNRSPHKI 3592
I + S +P ++LK++ F D+W FRK F Q A F F+L +N +P +
Sbjct: 3608 ILKEVQSNMVPRSMLKEWALHTFPNATDYWTFRKMFTIQLALIGFAEFVLHLNRLNPEML 3667
Query: 3593 FVDEKSGNVHTLEMLPSRYSYERVNQYAKQFETNLPNSAPVFHNNEPVPFRMTPNIQKLI 3652
+ + +G ++ F ++ ++ N PVPFR+TPNI + +
Sbjct: 3668 QIAQDTGKLN-----------------VAYFRFDINDATGDLDANRPVPFRLTPNISEFL 3710
Query: 3653 GDSAMEGVFSVGLFVIARALLEPDHELNTYLSLFIRDEVISWYSSMNRSI---------- 3702
+ G + + +AR +P+ +++ L +RDE+I+W+
Sbjct: 3711 TTIGVSGPLTASMIAVARCFAQPNFKVDGILKTVLRDEIIAWHKKTQEDTSSPLSAAGQP 3770
Query: 3703 --VEDPHLYAIVLTNVDLIIRKVAQFGHMSSSPSVATQYVLDAISAAVSPRNLAKCDQSF 3760
++ L ++V V I+ ++ S V ++AA S NL + D ++
Sbjct: 3771 ENMDSQQLVSLVQKAVTAIMTRLHNLAQFEGGES----KVNTLVAAANSLDNLCRMDPAW 3826
Query: 3761 MAWL 3764
WL
Sbjct: 3827 HPWL 3830
Score = 214 bits (546), Expect = 2e-54
Identities = 132/468 (28%), Positives = 235/468 (50%), Gaps = 32/468 (6%)
Query: 1 MESTDTHERMDTFVERIRDTEDVAE-RHAIISELYDVLDVVTSSVEYDEFXXXXXXXXXX 59
++ T ++ FV + D E + ++ E+ + + VTSS +Y F
Sbjct: 12 VDQTTLMKKYLQFVAALTDVNTPDETKLKMMQEVSENFENVTSSPQYSTFLEHIIPRFLT 71
Query: 60 XXNDDQISMNASSPEHKLRNTCLELLNRCPLNDKMEPMAMEVLQCLLKILTLENDENGVL 119
D ++ P +LR LE+++R P N+ + P VL + + L EN+EN ++
Sbjct: 72 FLQDGEVQFLQEKPAQQLRKLVLEIIHRIPTNEHLRPHTKNVLSVMFRFLETENEENVLI 131
Query: 120 CMKILTSLFKCYKQPLESEVNTFIKIIVGIYENVPNLVASTFLGEEETSSSTADSQDFSN 179
C++I+ L K ++ P+ E++ F+ + IY+ +P +V F + +T +
Sbjct: 132 CLRIIIELHKQFRPPITQEIHHFLDFVKQIYKELPKVVNRYFENPQVIPENTVPPPEMVG 191
Query: 180 S--------NNEEDAFENLSAPSKKHLEKATESFKTLSECPITMVTLFSSYKHLILVDLP 231
N E E+ + + + + S K L+E PI +V ++ YK I +
Sbjct: 192 MITTIAVKVNPER---EDSETRTHSIIPRGSLSLKVLAELPIIVVLMYQLYKLNIHNVVA 248
Query: 232 TFLPLVIDLLTLEVKQQQKSREELEAKGEKLIGMSSEIKNRSAFCDYVLAQIKATSFLAY 291
F+PL+++ + ++V Q + + + N+ + D++ AQIK SFLAY
Sbjct: 249 EFVPLIMNTIAIQVSAQARQHK---------------LYNKELYADFIAAQIKTLSFLAY 293
Query: 292 VFIRGYATDILKLHVKKVPDLVMRLLQDCPSELSSARKELLHATRHILSTSYKKLFLPKI 351
+ IR Y + K + V + ++LL +CP+E + RKELL A +HIL+T + F+P +
Sbjct: 294 I-IRIYQELVTKYSQQMVKGM-LQLLSNCPAETAHLRKELLIAAKHILTTELRNQFIPCM 351
Query: 352 NLMFDQKVLIGDGFTSYETLRPLAYSTLADFIHNIRSDLAMADIEKTVKMYTSFLLDESL 411
+ +FD+ +LIG G+T+ ETLRPLAYSTLAD +H++R L ++D+ V+++ + DESL
Sbjct: 352 DKLFDESILIGSGYTARETLRPLAYSTLADLVHHVRQHLPLSDLSLAVQLFAKNIDDESL 411
Query: 412 ALTVQIMSAKXXXXXXXXXXXXGKKDAYEVPKAKKLLMTIIEAYTSRF 459
++Q MS K K E + +LM ++E + +F
Sbjct: 412 PSSIQTMSCKLLLNLVDCIR---SKSEQESGNGRDVLMRMLEVFVLKF 456
>7302249 [TBLD] KOG0889 Histone acetyltransferase SAGA TRRAP/TRA1 component
PI-3 kinase superfamily
Length = 3435
Score = 1050 bits (2716), Expect = 0.0
Identities = 863/3305 (26%), Positives = 1525/3305 (46%), Gaps = 341/3305 (10%)
Query: 669 EGIDPSTVKAHFDITTPSLPVSATKDGRELMDYFAIIFMQIDSPVFNEIVESEIVFIYES 728
E +D T+ + + S +S +K+ +E++++F+ IF+ + S F EI + I F+ E
Sbjct: 263 EALDIYTINVNPNQQRTSGLISRSKEEKEVLEHFSGIFLMMHSQNFQEIFSTTINFLVER 322
Query: 729 LLRDSALLHVAQSFLTSEITSPNFTGILLKFLNSKLPELGNVDSNKSNILIRLFKLSFMS 788
+ ++ +L +A SFL + TSP F +L+++L +K+ E+G+ + +SN+ +RLFKL F S
Sbjct: 323 IYKNQSLQVIANSFLANPTTSPLFATVLVEYLLNKMEEMGS-NLERSNLYLRLFKLVFGS 381
Query: 789 VNLFPITNEAVLLPHLNNLILDSLKYSTEAEEPLVYFYLIRTLFRSIGGGRFENLYRSIK 848
V+LFP+ NE +L PHL+ ++ S++ + +EEP YF L+R LFRSIGGG + LY+
Sbjct: 382 VSLFPVENEQMLRPHLHKIVNRSMELALISEEPYNYFLLLRALFRSIGGGSHDLLYQEFL 441
Query: 849 PILQTLLQSLNKMIQTACRPHERDLYVELCLTVPVRLSVLAPYLNYLMKPLVYALVGFPE 908
P+L LL+ LN++ + H RDL+VELCLTVPVRLS L PYL LM PLV AL G P
Sbjct: 442 PLLPNLLEGLNRLQSGFHKQHMRDLFVELCLTVPVRLSSLLPYLPMLMDPLVSALNGSPT 501
Query: 909 LITQGLRTLELCIDNLTPEYLDPILEPVVGDVMKALFDLLKPQPFNHQISHTTVRILGKL 968
LI+QGLRTLELC+DNL P++L ++PV +M+AL+ L+ Q + R+LGK
Sbjct: 502 LISQGLRTLELCVDNLQPDFLYDHIQPVRAALMQALWKTLRNQ---DNAALVAFRVLGKF 558
Query: 969 GGRNRRFIETPKDLK--TETELNIEVDAWFNIYGFNSEVPLSITPGVNSASDILKDYRVN 1026
GG NR+ + P+ L + I + +F Y + + + + SA L +
Sbjct: 559 GGGNRKMMVEPQALSYIINDKPTISIVTYFQEY--ETPIDFPVDEAIKSAFRALGSNSTD 616
Query: 1027 LFYRKSAYKYLSTVLMLLLGSVGPIPKNLTECLQKGVKLLNSEELEDNIQFNDEKVVDPG 1086
FYR+ +++ + L + +L + +KL + +N N
Sbjct: 617 QFYRRQSWEVIRCFLAAFI--------SLDDEKHMLLKLFTHVDFVENKIMNWSTFQHKA 668
Query: 1087 KFNNXXXXXXXXXXCMFYAASIKELQEDVTVLVNKIVTHFSLLQVNEALSEKRRQPHVFS 1146
M A++ K+L++ V ++ +V H++++ + +Q F
Sbjct: 669 GNETVRETHQTALIGMLVASATKDLRDSVCPVMAAVVRHYTMVAI-------AQQAGPFP 721
Query: 1147 VDVKQPDVSISCDILLKAIRNGLCSYLEDSRALAIEAIKKVHDIGKVIYGD-TLYLEHSF 1205
Q I IL+ A+ + + ++ I + + D I G+ +
Sbjct: 722 QKGYQATHGIDPMILIDALASCMGHEEKELCKPGIACMGIILDTATNIMGNKDRACKLPI 781
Query: 1206 ITTLMRTFIHQCYSETYYEKRAGMXXXXXXXXXXXXPVHYVKNFQYGLTSGLLFVLKDTH 1265
I L + CY +Y K G + F + +FVL D
Sbjct: 782 IQYLAEKMVSLCYDRPWYSKVGGCQAIQFLCKHMSLRALFQNLFNF--LKAFMFVLMDLE 839
Query: 1266 AEAPLFITEDAKALLYEVIEVTCADVKE--ENLGDKHLQNSLT-----DIVCELSNPTEI 1318
+ E K+ + ++E+ + E +N+ K LQ T ++V +++P I
Sbjct: 840 GDVSNGAIEITKSYMKSMLEICLTPINECYKNIDLKDLQAKATYEVIHELVRHITSPNTI 899
Query: 1319 VRNVCQECLGKISTLTKIPVVTLMNHAKNFLLSPIFAKP--LRALPFSMQIGNVDAVIYC 1376
VR L I T+ V +M+ K+ L I K LR P + QIG +D +C
Sbjct: 900 VREESMVLLKHIGTIQSKTVSEVMDPHKDVLADIIPPKKHLLRHQPANAQIGLMDGNTFC 959
Query: 1377 LRLQNSFLKFD-----EELFRLLHESIALVDADDISLASTQRITEYQTSQQLIKLRVVCI 1431
L+ D +LF HE + L +A+D +LA ++ Y+ LI LR +
Sbjct: 960 TTLEPRLFTIDLTNTYHKLF--FHELLTLSEAEDATLA---KLDCYKNVPNLIPLRTSAL 1014
Query: 1432 RLLAQALLNPEFANAQNGSIRIKVLAVFFKTMLKPSPEIIEATYEGLKIVLAENSKLPKE 1491
R LA + + K++ + FK M E+ + +K + L KE
Sbjct: 1015 RALAACHYISDIGYKE------KIINIIFKVMESDKSELQTTAFHCMKHFIT-GVTLEKE 1067
Query: 1492 LLQNGLKPMLMNLSDHQKLTVPGXXXXXXXXXXXIAYFKVEIGKKLSDHLDAWCQIEVLD 1551
+Q+ ++P+L+ L DH+ L++P F ++ +++ H +I V +
Sbjct: 1068 KVQSAMRPLLLKLGDHRNLSIPAIKRLSYFTQIFPQMFNEKLSEQILQHCSKIMEIFVSE 1127
Query: 1552 --------TLFGKEITQQTPTKIICSIFNIFHLLPPQAGI-FLNELVFKLISLERKLRLQ 1602
F + KI+ I F++ A + ++ +L ++ E+ L ++
Sbjct: 1128 YKSTSPNVNFFASSKGGEYEQKIVILIEMFFYI---SASVKYIEKLCQLVLKTEKNLMIE 1184
Query: 1603 LDSPFRVPLAKYLNRFHVQVLTYFKTN--MRSRQLVLLMCSIIQKKEAPVLRKAFEPQLR 1660
SP+R L K+L RF + + F T M Q L +++ + R +
Sbjct: 1185 ASSPYREALIKFLQRFPTETVDLFLTESLMIDPQWNRLFIYLLKHETGVSFRAVIKSSRY 1244
Query: 1661 EFLKFYVEKIPENPVRVVSFFANSIDLVYVYHTSNEESWILENSDILFELKSMLTTVLKL 1720
L Y+ E P + + L+ +++ WI DI+ LK+ L
Sbjct: 1245 NNLIHYLNTHTEFPEALKYEIQHQAVLIIFTLMESDDQWIPTRQDIVDALKNCWQNYLST 1304
Query: 1721 INENSFNIDILQLNQSIEKFQMIYLAYLKQKKYDVPLFLEMIQYSYDNDLKIPNEVNSFI 1780
++ D+ L I L Y D+ L ++++ + + F+
Sbjct: 1305 LSSEDVLCDLWHL------IGKILLHYFSNNTNDIELLFQLLRALCFRFIPDVYFLRDFL 1358
Query: 1781 FDDIISCVDVQLKRK---YILECLQFSLREERSLKARNFVIKRVVNSIMI---HESTTKN 1834
+ V KR Y +E S E LKA +++ +++I S K
Sbjct: 1359 QHTVAQSFTVNWKRNAFFYFVENFNNSFLSE-ELKA------KIITAVIIPCFAVSFDKG 1411
Query: 1835 SVDELISPDNEIFAFLNQHIWNPKSSSVVLNTVIGK----LDSIRFELLQLTSILLKYAP 1890
++LI + ++I SV +N V D++R LLQL +L++ A
Sbjct: 1412 EGNKLIGAPPTPYQEDEKNI-----VSVFINKVFDPDKQYDDAVRIALLQLACLLVERAS 1466
Query: 1891 TLLEP----------VKRDLIKFAWKFIKLE---DIQLKQAAYVTTSLFISKFDLPVNIV 1937
+ R L+ FAW + + D + ++ S I++ + IV
Sbjct: 1467 QHIHDGDANNKRQGNKLRRLMTFAWPCLLSKSSVDPTARYHGHLLLSHIIARLAIHKKIV 1526
Query: 1938 TQVFVAILRVHQIEARFMVKESLDLLAPVVADRSKGSEEPTTWVNWVRRVILESN--FQQ 1995
QVF ++L+ H +EAR +VK++LD+L P + R + T +W +++I+E QQ
Sbjct: 1527 LQVFHSLLKGHALEARSIVKQALDVLTPAMPLRMEDGN--TMLTHWTKKIIVEEGHAMQQ 1584
Query: 1996 NTILYQFLISQKDIFFPYKDMFIPNIISYIGRLTLLTNPSTENQTLTIDLCDLVMYWEKQ 2055
+ Q +I ++FP + + ++I+Y+ RL S E++ L +DL ++++ WE
Sbjct: 1585 LFHILQLIIRHYKVYFPVRHQLVQHLINYMQRLGFPPTASIEHKKLAVDLAEVIIKWELH 1644
Query: 2056 TFSAQSKDDPDVNMDGS-EGIVTSSSTSLSQREAFAAFLIRFICVSNHRACETPLGSKAL 2114
+ KDD + DG+ E ++ SS S + F + ET + K +
Sbjct: 1645 ----RIKDDRETKTDGTEEELIQESSVKRSGIDLVETRKKSFDIIR-----ETTVQGKCV 1695
Query: 2115 SVLTELLSIGYLPEAV-VKLSYFEKFLIQQDLESANLLYYCMNALDVLDIIFRTKDPKWI 2173
+L + P+ +KL++ +K L + NL C +D L + P +
Sbjct: 1696 MLLKMAMRPEIWPQPFDIKLNWLDKVLATVETPHHNLNNIC-TGIDFLTFLTTILSPDQL 1754
Query: 2174 INNLKTIQTLLDKC-LHANHHDLQEALQKVLSTVLTAVKDDDVPFESEEDTDSKVFVNLV 2232
++ ++ +Q L C +H N + +++ LT + P + D + V
Sbjct: 1755 VSIIRPVQRGLSLCIIHQN-----TRIVRLMHMFLTRIMAIFPPDTQHKHEDLDLLYTAV 1809
Query: 2233 SSIISENLN--------GTTSVAAGVILCWTLFVNIPSQIDVLLPLLMKTFNKLCKDHL- 2283
S +I+ENL +S+ +++ N S ID +L ++ N L +DH+
Sbjct: 1810 SKMIAENLTSYEKSPQPNASSLFGTLMILKACTTNNASYIDRILVQFIRVLNHLTRDHIN 1869
Query: 2284 ------TISQPKDATA--VEDARITTKLLKKVFYILSFKVSTLGDSRRPFLSTVAL-LID 2334
ISQ D+ A +E ++ +L+K +++S ++ R+ F+ T+ + LI+
Sbjct: 1870 TIGGNTVISQSPDSNALPLELLVLSLELIKNRIFVMSVEI------RKLFIGTILVSLIE 1923
Query: 2335 RSMDQNFLQKIVLIAKNWVFTNE-----IFPTVKEKAAILTKML---AFEIRGEPHLSKQ 2386
+S + ++ I+ + W+ T E P+++EK+A+L K++ + E L+ Q
Sbjct: 1924 KSTEVKIIKCIIKMLDEWIKTKEPNVMTQVPSIREKSALLVKLMQNVEKKFTDEIELNIQ 1983
Query: 2387 FYEIILQLFENKKYNNSEITVRMEQPFLVGTRISDIKLRSKLMNILNGSLDNDIKERLYY 2446
F EII ++ ++ +E+T ++E FL G R + +RSK IL+ S+ + +RL Y
Sbjct: 1984 FLEIINFIYRDEILKQTELTNKLEGAFLNGLRFQNPNVRSKFFEILDSSMRRRLHDRLLY 2043
Query: 2447 VVRDQNWEFVADYMWLSQACQLLFGACVMEHRIK----------LTEHFPLSPLSAIERN 2496
++ Q W+ + + W+ Q +LL +I+ +T P++ E +
Sbjct: 2044 IICSQAWDTIGSHYWIKQCIELLILTANTMMQIQCSNEQFKIPSITSVIPVNSSETQENS 2103
Query: 2497 II---------------VEDEDKVI------------------TNSALESLIREHQSFID 2523
+ V+D+D V L L+ + F++
Sbjct: 2104 FVSFLSSHSESFDIIQTVDDKDDVYDIDLNADRKEDCQQILPNRRVTLVELVYKQAEFLE 2163
Query: 2524 KINSIKCCDIINPLVDIFYQSPEAVRATWVNVFPVAYKSIPRNEKYGFVRSLVALLSKDY 2583
+I+ ++ + + + ++ W+++FP + +++ + L+ LS
Sbjct: 2164 ANRNIRTDQMLVATSQLCHIDTQLAQSVWLSMFPRIWSIFTEDQRCNITKELIPFLSSGT 2223
Query: 2584 HTKQASIHVNVISTMLESVSK-IESLELPPHLVRYLGITFNAWYQSIDLLE-----QIQE 2637
+ Q H + ++T +ES++K + +PP+L+ YLG + N W+++I +LE Q +
Sbjct: 2224 NVNQKDCHPSTLNTFVESLTKCAPPIYIPPNLLAYLGKSHNLWHRAILVLEDMAVNQSMQ 2283
Query: 2638 TSNIDNSK----ILDTNE-----DALLELYSSIQEDDMFYGLWRRKAKYTESSIALSYEQ 2688
+ +ID + LD + D+L ++YSS+ E+D++ GLW + A Y E++IA+SYEQ
Sbjct: 2284 SKDIDGGENQFSDLDVQQSNNIFDSLSKMYSSMHEEDLWAGLWLKFAHYPETNIAVSYEQ 2343
Query: 2689 IGLWDKAQQMYEAAQVK-----ARGGFLPYSESEYELWEDNWILCASKLQHWDILTELAK 2743
+G +++AQ Y+ A K + G Y SE LWE++W+ CA +L WDIL + A+
Sbjct: 2344 MGFFEEAQGAYDLAMTKFKQDLSNGVVNTYVNSELLLWENHWMRCAKELNQWDILLDYAQ 2403
Query: 2744 HEGFTD--LLLECGWRVAEWNADREALEHSVKSVMDVPTPRRQIFETFLALQQFGETKKG 2801
+ L+LE WRV +WN + AL + + + + +++ +L++ E + G
Sbjct: 2404 TNKDKNMFLILESSWRVPDWNLMKIALAKTEQCYLKHYGFKINLYKGYLSILHQEERQTG 2463
Query: 2802 DQEVRRLCDEGIQLSLKKWHSLPKRYTPAHKALLHSFQQYMEFLEATQIYANLASTTVQN 2861
+ + R + L +++W LP + H L + QQ ME EA+QI+ LA Q+
Sbjct: 2464 N--IERYVEIASSLCIREWRRLPNIVSHIHLPYLQASQQIMELHEASQIHQGLA----QS 2517
Query: 2862 LDTKAQEIKRVLQAWRDRLPNIWDDITIWDDLVTWRQHVFNVINSAYLPLVPALQQANSN 2921
+ ++K +++ WR+RLP I DD++ W D+ TWRQH + +I QQ++
Sbjct: 2518 RNNSLHDMKAIVKTWRNRLPIISDDLSHWSDIFTWRQHHYQIITQ------HLEQQSDQG 2571
Query: 2922 SNINTHAYRGYHEIAWVINRFAHVARRHNMPDVCISQLARIYTLPNIEIQEAFLKLREQA 2981
S + G H A I F +AR+HN+ VC L+RIYT+P++ I + F K+R+Q
Sbjct: 2572 STM-----LGVHASAQAIISFGKIARKHNLTGVCQETLSRIYTIPSVPIVDCFQKIRQQV 2626
Query: 2982 KCHYQ-----NMNELTTGLDVISNTNLVYFGTVQKAEFFTLKGMFLSKLRAHDEANQAFA 3036
KC+ Q NE+ L+VI +TNL YF AEF+ LKG+ L+++ +EA ++F+
Sbjct: 2627 KCYLQMPSTSGKNEINEALEVIESTNLKYFTGEMNAEFYALKGLLLAQIGRSEEAGKSFS 2686
Query: 3037 TAVQIDLNLAKAWAQWGFFNDRRLSEEPKNISFASNAMSCYLQAAGLYKNSKTRKLLSRI 3096
A Q+ L KAWA WG + ++ +E K I+ A +A+ CYLQA+ SKTRK ++++
Sbjct: 2687 VAAQLHDGLTKAWAMWGDYMEQIFLKERK-ITLAVDALICYLQASRNQIESKTRKYIAKV 2745
Query: 3097 LWLLGRDDSSNSLAYAFDSFRGEIPVWYWITFIPQLLTALSHKEAFLVRKILIRIAKSYP 3156
LW L D+++ L + IP YW+ +IPQLL L E ++ +L +I + YP
Sbjct: 2746 LWFLSYDNNTKILISTLEKHVAGIPPSYWLPWIPQLLCCLEQFEGDVILNLLSQIGRLYP 2805
Query: 3157 QALHFQLRTTKEDFAVIQRQSLALARTQGEPAETENQENSKHPSPDNSRTTSQNKSQDQD 3216
QA++F +RT L L Q E +T Q S + T S +
Sbjct: 2806 QAVYFPIRTL----------YLTLKIEQREKHKTAEQAVKSSCSNIDGTTLSFGRGASHG 2855
Query: 3217 MYPN-----NRQPWEYLEELNGILKTAYPLLALSLESLVDQINQKFKTNPDEDLFRLINV 3271
P+ P ++ + + +P + SLE +VDQ+ F+ + E++ R +
Sbjct: 2856 NIPSINPIKATPPMWRCSKVMQLQREVHPTILSSLEGIVDQM-VWFRESWTEEVLRQLRQ 2914
Query: 3272 LLI--------------DGTYNYNRLPYPR----------EKPPLPSSTEANLIRFSENL 3307
LI T + L + + E P ++ + SE+L
Sbjct: 2915 GLIKCYAIAFEKRDTVQHSTITPHTLHFVKKLGSTFGIGIENVPGSVTSSISNSAASESL 2974
Query: 3308 -----------LPPNIRVKFNADFIESKP---DFEVYIKRLRFWRNRLENKLDRAPKVES 3353
+ ++ +F DF SKP I +L+ W LE K+ + P
Sbjct: 2975 ARRAQVTFQDPVFQKMKEQFTNDFDFSKPGAMKLHNLISKLKTWIKVLETKVKKLPTSFL 3034
Query: 3354 MEAICPNLSNFHHQKFEDIKVPGQYLLNKDNNTHFVKIGRFMPEVDFTRGTHTSHRRLTI 3413
+E C LSNF QK ++++PG+ L+ ++ ++V+I RFMP V+ + +T+ RRL I
Sbjct: 3035 IEDKCRFLSNF-SQKTAEVELPGELLIPLSSH-YYVRIARFMPRVEIVQKNNTAARRLYI 3092
Query: 3414 RGHDGSLHSFAVQYPA-VRHSRREERMFQLYRLLNERLRKNVQTRRRDIQFTVPIAVPLS 3472
RG +G ++ + V + + +RREER+ QL R+LN L K +T RR + TVP VP+S
Sbjct: 3093 RGTNGKIYPYLVVLDSGLGDARREERVLQLKRMLNYYLEKQKETSRRFLNITVPRVVPIS 3152
Query: 3473 PQVRVMSDSASFRTLHQIYDEFCAKKNMDRDAIQDFITEQLNVAHDKVLPPPDITAVKVE 3532
PQ+R+ D+ + +L +I+ + C +D D + ++ + P + E
Sbjct: 3153 PQMRLAEDNPNSISLLKIFKKCCQSMQVDYD--MPIVKYYDRLSEVQARGTPTTHTLLRE 3210
Query: 3533 IFSSIHSLFIPSTLLKDYYSKLFSEFEDFWLFRKQFASQYAAFVFMTFMLSINNRSPHKI 3592
IFS I +P TLLK + K F DFW FRK Q A L++ + +
Sbjct: 3211 IFSEIQWTMVPKTLLKHWALKTFLAATDFWHFRKMLTLQLALAFLCEHALNLTRLNADMM 3270
Query: 3593 FVDEKSGNVHTLEMLPSRYSYERVNQYAKQFETNLPNSAPVFHNNEPVPFRMTPNIQKLI 3652
++ + SG ++ SY F+ ++ + + + PVPFR+TPN+ + I
Sbjct: 3271 YLHQDSGLMN--------ISY---------FKFDVNDDKCQLNQHRPVPFRLTPNVGEFI 3313
Query: 3653 GDSAMEGVFSVGLFVIARALLEPDHELNTYLSLFIRDEVISWYSSMNR--SIVED----- 3705
+ G S + AR ++P+++L++ L +RDE+I+ R ++E
Sbjct: 3314 THFGITGPLSAAIVATARCFIQPNYKLSSILQTILRDEIIALQKKGFRECKLIEGSEDRY 3373
Query: 3706 ------PHLYAIVLTNVDLIIRKVAQFGHMSSSPSVATQYVLDAISAAVSPRNLAKCDQS 3759
H IV + VD+I + +F +S S+ + + + +A + NL + D +
Sbjct: 3374 SDGNCMEHSVNIVNSAVDII---MTRFNKISYFDSIENKKISVLVQSATNIDNLCRMDPA 3430
Query: 3760 FMAWL 3764
+ WL
Sbjct: 3431 WHPWL 3435
Score = 99.8 bits (247), Expect = 8e-20
Identities = 53/150 (35%), Positives = 89/150 (59%), Gaps = 4/150 (2%)
Query: 313 VMRLLQDCPSELSSARKELLHATRHILSTSYKKLFLPKINLMFDQKVLIGDGFTSYETLR 372
++ L+++CP E + RKELL A RHI +T ++ F+P I +FD+ +LIG G T +++R
Sbjct: 1 MLNLMKNCPKEAAHLRKELLIAARHIFATDLRQKFIPSIEQLFDEDLLIGKGVT-LDSIR 59
Query: 373 PLAYSTLADFIHNIRSDLAMADIEKTVKMYTSFLLDESLALTVQIMSAKXXXXXXXXXXX 432
PLAYSTLAD H++R L + + K V +++ + DESLA+ +Q MS K
Sbjct: 60 PLAYSTLADLAHHVRQSLNIDVLIKAVNLFSKNVHDESLAVGIQTMSCKLLLNLVDCLRH 119
Query: 433 XGKKDAYEVPKAKKLLMTIIEAYTSRFKLL 462
+ E ++K LL +++ + +F+ +
Sbjct: 120 HSET---EPQRSKALLSKLLKVFVKKFETI 146
>CE05429 [TBLD] KOG0889 Histone acetyltransferase SAGA TRRAP/TRA1 component
PI-3 kinase superfamily
Length = 3944
Score = 303 bits (775), Expect = 5e-81
Identities = 268/969 (27%), Positives = 450/969 (45%), Gaps = 114/969 (11%)
Query: 70 ASSPEHKLRNTCLELLNRCPLNDKMEPMAMEVLQCLLKILTLENDENGVLCMKILTSLFK 129
A + +LR LE++ R + M+ + E+++ +++++T+EN+EN L +KI+T +
Sbjct: 85 AENNTQQLRKLMLEIILRLSNVEAMKHHSKEIIKQMMRLITVENEENANLAIKIVTDQGR 144
Query: 130 CY-KQPLESEVNTFIKIIVGIYENVPNLVASTFLG------EEETSSSTADSQDFSNSNN 182
K EV+ +I+V V +L AS G E + ST+ +
Sbjct: 145 STGKMQYCGEVS---QIMVSFKTMVIDLTASGRAGDMFNIKEHKAPPSTSSDEQVITEYL 201
Query: 183 EEDAFENL-------SAPSKKH--LEKATESFKTLSECPITMVTLFSSYKHLILVDLPTF 233
+ ++ P K+ + A +S K L E P ++ + +K I + F
Sbjct: 202 KTCYYQQTVLLNGTEGKPPLKYNMIPSAHQSTKVLLEVPYLVIFFYQHFKTAIQTEALDF 261
Query: 234 LPLVIDLLTLEVKQQQKSREELEAKGEKLIGMSSEIKNRSAFCDYVLAQIKATSFLAYVF 293
+ L +D L + V + K + N+ D+V AQ + FL++V
Sbjct: 262 MRLGLDFLNVRVPDEDKLKT-----------------NQIITDDFVSAQSR---FLSFVN 301
Query: 294 IRGYATDILKLHVKKVPDLV---MRLLQDCPSELSSARKELLHATRHILSTSYKKLFLPK 350
I + L ++ P LV M++L+ CP++L S R+E+L A ++ S K F P
Sbjct: 302 IMAKIPAFMDLIMQNGPLLVSGTMQMLERCPADLISVRREVLMALKYFTSGEMKSKFFPM 361
Query: 351 INLMFDQKVLIGDGFTSYETLRPLAYSTLADFIHNIRSDLAMADIEKTVKMYTSFLLDES 410
+ + ++V++G GFT+ E LR Y LAD +H++R+ + I + ++ L D +
Sbjct: 362 LPRLIAEEVVLGTGFTAIEHLRVFMYQMLADLLHHMRNSIDYEMITHVIFVFCRTLHDPN 421
Query: 411 LALTVQIMSAKXXXXXXXXXXXXGKKDAYEVPKAKKLLMTIIEAYTSRFKLLNSQHKKIL 470
+ VQIMSA+ K D+++ + LL+ I+E++ ++ K L H IL
Sbjct: 422 NSSQVQIMSARLLNSLAESLC---KMDSHDT--TRDLLIEILESHVAKLKTLAVYHMPIL 476
Query: 471 KQHNVYEQSKNKKSKEIQDQLAKDRHDVDEYMVNILKSTDELLPSS----VTVDTNADVD 526
Q E KS E D ++ +NI K T +P +++D+ +++
Sbjct: 477 FQQYGTEIDYEYKSYE---------RDAEKPGMNIPKDTIRGVPKRRIRRLSIDSVEELE 527
Query: 527 GDITMSEEPDISEKGNSSVHSDNNTSLTVKNQDKNSDISFKENSVEILDFNDIQNHAPII 586
++ EP SE + S N K K S + IL P+
Sbjct: 528 ---FLASEPSTSEDADESGGDPNKLPPPTKEGKKTSPEA-------ILTAMSTMTPPPLA 577
Query: 587 LFQATSNDPLKDAFYLYRTLLSFLKTIIHDLKVFNPPPDEYTTMNPKMWSALSRVFSYEE 646
+ +A + L + ++ K + L++ P D Y + R+ Y
Sbjct: 578 IVEARN---------LVKYIMHTCKFVTGQLRIARPSQDMYHCSKER--DLFERLLRYG- 625
Query: 647 VIVLKNLFHECIAGLHLFSSNPEGIDPSTVKAHFDITTPSLPVSA-TKDGRELMDYFAII 705
++ ++F + P+T P + S TKD ++ ++ A +
Sbjct: 626 -VMCMDVF----------------VLPTTRNQ------PQMHSSMRTKDEKDALESLANV 662
Query: 706 FMQIDSPVFNEIVESEIVFIYESLLRDSALLHVAQSFLTSEITSPNFTGILLKFLNSKLP 765
F ID +F EI E + F+ E + + L + + P F +L FL S++
Sbjct: 663 FTTIDHAIFREIFEKYMDFLIERIYNRNYPLQLMVNTFLVRNEVPFFASTMLSFLMSRM- 721
Query: 766 ELGNVDSNKSNILIRLFKLSFMSV--NLFPITNEAVLLPHLNNLILDSLKYSTEAEEPLV 823
+L V ++K+ + ++LFK+ F ++ N + + +L +L ++ S + A EPL
Sbjct: 722 KLLEVSNDKTMLYVKLFKIIFSAIGANGSGLHGDKMLTSYLPEILKQSTVLALTAREPLN 781
Query: 824 YFYLIRTLFRSIGGGRFENLYRSIKPILQTLLQSLNKMIQTACRPHERDLYVELCLTVPV 883
YF L+R LFRSIGGG + LY +L LLQ LNK+ R R+L+VELCLTVPV
Sbjct: 782 YFLLLRALFRSIGGGAQDILYGKFLQLLPNLLQFLNKLTSCQHRIQMRELFVELCLTVPV 841
Query: 884 RLSVLAPYLNYLMKPLVYALVGFPELITQGLRTLELCIDNLTPEYLDPILEPVVGDVMKA 943
RLS L PYL LM PLV A+ G P ++TQGLRTLELC+DNL PEYL + PV G +M+
Sbjct: 842 RLSSLLPYLPLLMDPLVCAMNGSPNIVTQGLRTLELCVDNLQPEYLLENMLPVRGALMQG 901
Query: 944 LFDLLKPQPFNHQISHTTVRILGKLGGRNRRFIETPKDLKTETELNIEVDAWFNIYGFNS 1003
L+ ++ P ++ RILGK GG NR+ + P+ L+ T + ++ F+ G +
Sbjct: 902 LWRVVSKAPDTSSMT-AAFRILGKFGGANRKLLNQPQILQVATLGDSYINMEFSRMGLDG 960
Query: 1004 ----EVPLS 1008
+PLS
Sbjct: 961 NHSIHLPLS 969
Score = 223 bits (569), Expect = 4e-57
Identities = 314/1618 (19%), Positives = 658/1618 (40%), Gaps = 209/1618 (12%)
Query: 1717 VLKLINENSFNIDILQLNQSIEKFQMIYLAYLKQKKYDVPLFLEMIQYSYDNDLKIPNEV 1776
++K + E+ + + L LN +L YL+ YD LF+ + N + + +
Sbjct: 1713 IVKRMTEHKYKVPKLILNT--------FLRYLRLNIYDYDLFIVIASCFNGNFVTDLSFL 1764
Query: 1777 NSFIFDDIISCVDVQLKRKYILECLQFSLREERS-------LKARNFVI----------- 1818
++ ++I V +Q +R+ L +Q + ++ +KA +++
Sbjct: 1765 REYLETEVIPKVPLQWRRELFLRIMQKFDTDPQTAGTSMQHVKALQYLVIPTLHWAFERY 1824
Query: 1819 --KRVVNSIMIHESTTKNSVDELISPDNEIFAFLNQHIWNPKSSSVVLNTVIGKLDSIRF 1876
+V + I +S + VD S DN + + +SV+ + D +
Sbjct: 1825 DTDEIVGTAPIDDSDSSMDVDPAGSSDNLV----------ARLTSVIDSHRNYLSDGMVI 1874
Query: 1877 ELLQLTSILLKYAPTLLEPVK--------RDLIKFAWKFIKL---EDIQLKQAAYVTTSL 1925
QL ++ ++ A + R L+ FAW + + +D ++ + +
Sbjct: 1875 VFYQLCTLFVQNASEHIHNNNCKKQGGRLRILMLFAWPCLTMYNHQDPTMRYTGFFFLAN 1934
Query: 1926 FISKFDLPVNIVTQVFVAILRVHQIEARFMVKESLDLLAPVVADRSKGSEEPTTWVNWVR 1985
I +F + IV QVF ++ +Q + R +++++D+L P + R++ + ++ V+
Sbjct: 1935 IIERFTINRKIVLQVFHQLMTTYQQDTRDQIRKAIDILTPAL--RTRMEDGHLQILSHVK 1992
Query: 1986 RVILES--NFQQNTILYQFLISQKDIFFPYKDMFIPNIISYIGRLTLLTNPSTEN---QT 2040
++++E N Q ++Q ++ +++ + + +++ + R ++ N EN +
Sbjct: 1993 KILIEECHNLQHVQHVFQMVVRNYRVYYHVRLELLTPLLNGVQRALVMPNSVLENWQTRR 2052
Query: 2041 LTIDLCDLVMYWEK-QTFSAQS--KDDPDVNMDGS-EGIVTSSSTSL------------- 2083
+++C++V+ WE +T D+ + +D + + T+SST
Sbjct: 2053 HAVEICEMVIKWELFRTLKTDHIISDEEALEVDKQLDKLRTASSTDRFDFEEAHNKRDMP 2112
Query: 2084 -SQR-------EAFAAFLIRFICVSNHRACETPLGSKAL--SVLTELLSIGYLPEAVVKL 2133
+QR + L+RF C++ H+ + S+ L S+ E +S +L
Sbjct: 2113 DAQRTIIKEHADVIVNMLVRF-CMTFHQNSGSSSTSQTLRPSMWGEFVSF--------RL 2163
Query: 2134 SYFEKFL-------IQQDLES---ANLLYYCMNALDVLDIIFRTKDPKWIINNLKTIQTL 2183
+ EKFL ++ D+ S AN + + LD+L I ++ ++ +Q
Sbjct: 2164 TMIEKFLSIPNDNALRNDISSTAYANTIQNAQHTLDMLCNIIPVMPKTSLMTMMRQLQRP 2223
Query: 2184 LDKCLH--ANHHDLQEALQKVLSTVLTAVKDDDVPFESEEDTDSKV--FVNLVSSIISEN 2239
L +CL+ A + + + +++S +L + E + + F++ + +N
Sbjct: 2224 LIQCLNNGAQNFKMTRLVTQIVSRLLEKTNVSVNGLDELEQLNQYISRFLHEHFGSLLKN 2283
Query: 2240 LNGTTSVAAGVI-LCWTLFVNIPSQIDVLLPLLMKTFNKLCKDHLT-ISQPKDATAVEDA 2297
L+G G L T+ + P+ +D L+P +K + K+HL ++ +D V++
Sbjct: 2284 LSGPVLGVLGAFSLLRTICGHEPAYLDHLMPSFVKVMERAAKEHLAYVANSQDGNMVKNV 2343
Query: 2298 RITTKLLKKVFYILSFKVSTLG-DSRRPFLS-TVALLIDRSMDQNFLQKIVLIAKNWVFT 2355
+LL ++ +V + + +R + +A LI +S +Q V + + T
Sbjct: 2344 ---AELLCACMELVRPRVDHISMEIKRSIVGGIIAELIIKSNHDKIIQTSVKLLGAMIST 2400
Query: 2356 NEIFPTVKEKAAILTKM---LAFEIRGEPHLSKQFYEIILQLFENKKYNNSEITVRMEQP 2412
++ T+ +L ++ + + + L + +++ +FEN +Y NSE R+ +
Sbjct: 2401 QDMEFTILTVLPLLVRIQSIIVTKFKNCKDLIADYLVVVITVFENSEYRNSEAGSRLWEG 2460
Query: 2413 FLVGTRISDIKLRSKLMNILNGSLDN----DIKERLYYVVRDQNWEFVADYMWLSQACQL 2468
F G + SD + R K + + + DI R+ Y++++Q+W WL A
Sbjct: 2461 FFWGLKSSDPQTREKFSIVWEKTWPHMATVDIAHRMKYIMQNQDWSKFKHAFWLKFALWG 2520
Query: 2469 LFGACV---------------MEHRIKLTEHFPLSPLSAIERNIIVEDED----KVITNS 2509
+ ME ++ P P+ E++ + +D K
Sbjct: 2521 MLRTIAKRPTDPNNKRKKDQPMEVETEMKREEP-EPMEVDEKDSQDDSKDAGEPKEKEKL 2579
Query: 2510 ALESLIREHQSFIDKINSIKCCDIINPLVDIFYQSPE--AVRATWVNVFPVAYKSIPRNE 2567
LE L+ Q +D+ ++ D ++ + I + E WV +F + S+ ++E
Sbjct: 2580 TLELLLAGQQELLDEASNYDFADALDTVSQITFALNENQVTSKMWVVLFKSFWSSLSQSE 2639
Query: 2568 KYGFVRSLVALLSKDYHTK-QASIHVNVISTMLESVSKIESLELPPHLVRYLGITFNAWY 2626
F +V +S H Q + +V++ LE+V +++ LP L+ ++ W+
Sbjct: 2640 IEDFTALVVPFMSSGVHNNYQTGVQDSVLAVWLEAVG--DAVHLPSRLIEFISSKHECWH 2697
Query: 2627 QSIDLLEQIQET--SNIDNSKILDTNE-----------DALLELYSSIQEDDMFYGLWRR 2673
I LLE T ++N+ + + ++L LY+ I E D F +W R
Sbjct: 2698 TGIRLLENHIWTIPKQLNNTLLREMKVAPGLAGDIETLESLGTLYNEISEFDQFAAIWER 2757
Query: 2674 KAKYTESSIALSYEQIGLWDKAQQMYEAAQ----------------VKARGGFLPYSESE 2717
+A + ++ A+S Q+G + AQ E + + P + E
Sbjct: 2758 RAVFPDTMRAMSAMQLGDMELAQSYLEKSMSSTYETLAPTINPNNTSNSEKHVSPIIDKE 2817
Query: 2718 YELWEDNWILCASKLQHWDILTELAKHEGFTDL--LLECGWRVAEWNADREA---LEHSV 2772
Y+ W + +I S+L W + ++ + + L+ + +WN E + +
Sbjct: 2818 YDHWMEMYITNCSELLQWQNVADVCNGKDMQHVRGLINAASHIPDWNVVEECKSQIAGCI 2877
Query: 2773 KSVMDVPTPRRQIFETFLALQQFGETKKGDQEVRRLCDEGIQLSLKKWHSLPKRYTPAHK 2832
+ + T + + + + + E + + +W +LP + H
Sbjct: 2878 PPSFHLDYTLFNLMSTVMRMNENSSPTHMKERCKIAIQECTEAHISRWRALPSVVSYGHV 2937
Query: 2833 ALLHSFQQYMEFLEATQIYANLASTTVQNLDTKAQ-EIKRVLQAWRDRLPNIWDDITIWD 2891
+L + E E+T I L +D ++K +++ +R+R P DD+
Sbjct: 2938 KILQAMNLVREIEESTDIRIALLEAPSNKVDQALMGDMKSLMKVFRNRTPTTSDDMGFVS 2997
Query: 2892 DLVTWRQHVFNVI--NSAYLPLVPALQQANSNSNINTHAYRGYHEIAWVINRFAHVARRH 2949
WR + ++ Y V A N +I ++A + + A H
Sbjct: 2998 TWYDWRNQIHGMMLQRFEYWDKVGLNVAATGNQSIVPIHSMAQAQLA--VAKHAKNLGFH 3055
Query: 2950 NMPDVCISQLARIYTLPNIEIQEAFL----KLREQAK--CHYQNMNE-LTTGLDVISNTN 3002
N+ +++LA + +P ++ Q+ LR+ A + NE L L+V+ +
Sbjct: 3056 NLTKDLLNKLAGLTAIPMMDAQDKVCTYGKTLRDMANSAADERVKNELLCEALEVLEDVR 3115
Query: 3003 LVYFGTVQKAEFFTLKGMFLSKLRAHDEANQAFATAVQ-IDLNLA------KAWAQWG-- 3053
+ Q A + S L + A+ F+ A Q +DL + K WG
Sbjct: 3116 IDDLQKDQVAALLYHRANIHSVLDQAENADYTFSAASQLVDLQNSVTTTGIKLMKNWGHH 3175
Query: 3054 ----FFNDRRLSEEPKNISFASNAMSCYLQAAGLYKNSKTRKLLSRILWL---LGRDDSS 3106
FF+ E N F A++CY AA + + K RK +++ILWL L S
Sbjct: 3176 LYKRFFSTTVCKETGNN--FGRQALACYFIAARVDNDIKARKPIAKILWLSKHLNACGSH 3233
Query: 3107 NSLAYAFDSFRGEIPVWYWITFIPQLLTALSHKEAFLVRKILIRIAKSYPQALHFQLR 3164
+ + ++ W+ ++PQL+T + +K IL ++A ++P + + +R
Sbjct: 3234 EVMNRVIKKQLHSLNLFNWLYWLPQLVTDVRYKPNSNFVLILCKMAAAHPLQVFYHIR 3291
>ECU05g0540 [TBLD] KOG0889 Histone acetyltransferase SAGA TRRAP/TRA1 component
PI-3 kinase superfamily
Length = 3436
Score = 166 bits (420), Expect = 7e-40
Identities = 135/547 (24%), Positives = 246/547 (44%), Gaps = 57/547 (10%)
Query: 2656 ELYSSIQEDDMFYGLWRRKAKYTESSIALSYEQIGLWDKAQQMYEAAQVKARGGFLPYSE 2715
E+Y + + D +YG+ R + E+ A +Q+G +AQ +YE Q KA + + E
Sbjct: 2279 EIYRRLMDSDGYYGMSRSVCIFPETMQAYFLQQVGKTREAQDLYEKIQKKAGEHRISFDE 2338
Query: 2716 SEYELWEDNWILCASKLQHWDILTELAKHEGFTDLLLECGWRVAEWNADREALEHSVKSV 2775
+EY+ W+D WI CA +LQ WD+ E G L E W ++ + D++AL+ KS+
Sbjct: 2339 NEYKKWQDEWIRCARELQQWDVCYEAGIETGDYSLSTESLWHLSSFT-DQDALKR-FKSM 2396
Query: 2776 MDVPTP--RRQIFETFLALQQFGETKKGDQEVRRLCDEGIQLSLKKWHSLPKRYTPAHKA 2833
+D ++ ++ F + K +++ ++ + I L L+ S P +
Sbjct: 2397 VDTGKNGFEKEFYDAFASTY----AKYSAEKIGKILERNI-LELR---SYPAGSNAGSRF 2448
Query: 2834 LLHSFQQYMEFLEATQIYANLASTTVQNLDTKAQEIKRVLQAWRDRLPNIWDDITIWDDL 2893
LL+ Q +E +EA I+ + A+ + +L W+D+ P+ D W
Sbjct: 2449 LLY-LQIIIEMIEAEPIFNDRIDG--------AESLTSILFRWKDKEPSDQDVFEQWSLF 2499
Query: 2894 VTWRQHVFN---VINSAY------------------------LPLVPAL----QQANSNS 2922
TWR+H ++ +I Y +P+ L + +
Sbjct: 2500 RTWRRHAYSRLGMIEKTYGGETAYKAPGRSYAEEMAASPGRRVPMTSHLFSPKEMIEGSI 2559
Query: 2923 NINTHAY-RGYHEIAWVINRFAHVARRHNMPDVCISQLARIYTLPNIEIQEAFLKLREQA 2981
+ +G +E+A +N F+ A H D + L ++ L ++++ + F K+ +
Sbjct: 2560 KVKKELIAKGTNELAKTLNGFSKAAIEHGYYDAALFHLKEVFDLSSVKVGDVFQKVVYEL 2619
Query: 2982 KCHYQNMNELTTGLDVISNTNLVYFGTVQKAEFFTLKGMFLSKLRAHDEANQAFATAVQI 3041
C E G++ +TN+ +F Q + F +G+F KL +A + + +VQI
Sbjct: 2620 LC-LLGKKEYKIGVEQCGSTNIQHFSDSQSSVLFNFRGLFSEKLGKFSDAEKFYLQSVQI 2678
Query: 3042 DLNLAKAWAQWGFFNDRRLSEEPKNISFASNAMSCYLQAAGLYKNSKTRKLLSRILWLLG 3101
+ + W W F R++ E + +A LQA K RK + +++ L+
Sbjct: 2679 CNVVGENWLTWAKFLFNRINGE--GVGPKEDAFVALLQAVVYCNGKKARKGILKLILLMD 2736
Query: 3102 RDDSSNSLAYAFDSFRGEIPVWYWITFIPQLLTALSHKEAFLVRKILIRIAKSYPQALHF 3161
+ SS F EI + +I FIPQL+ LS ++A LV+ IL +I++ +PQA+
Sbjct: 2737 KH-SSLCDTDMFHKVLQEIDISRFIYFIPQLIGLLSKEDAELVQIILAKISEEHPQAIAG 2795
Query: 3162 QLRTTKE 3168
L+ +E
Sbjct: 2796 PLKAARE 2802
>SPBC30D10.10c [L] KOG0891 DNA-dependent protein kinase
Length = 2335
Score = 105 bits (262), Expect = 1e-21
Identities = 231/1158 (19%), Positives = 449/1158 (37%), Gaps = 178/1158 (15%)
Query: 2589 SIHVNVISTMLESVSKIE----SLELPPHLVRYLGITFNAWYQSIDL--LEQIQETSNID 2642
+I V ++ T+L +E +L +P ++ N + +++ L+ +QET
Sbjct: 1197 NISVEILQTLLNLAEYMEREDHTLPIPIKVISAHASKCNVYAKALHYTELQFVQETKE-- 1254
Query: 2643 NSKILDTNEDALLELYSSIQEDDMFYGLWRRKAKYTESSIALS-YEQIGLWDKAQQMYEA 2701
++ + ++L+ + + +Q+ D G+ + ++ + S+ + YE++ WD A YE
Sbjct: 1255 --EVSISTIESLITINNHLQQSDAAVGMLQYTKEHKQFSLKETWYEKLHRWDDALAAYEH 1312
Query: 2702 AQVKARGGFLPYSESEYELWEDNWILCASKLQHWDILTELAK----------HEGFTDLL 2751
+ + +S +E+ + C L WD L+ELA+ E L
Sbjct: 1313 REREG--------DSSFEI-NIGKLRCYYALGDWDHLSELAQKAWVTSEQEHREAIAPLA 1363
Query: 2752 LECGWRVAEWNADREALEHSVKSVMDVPTPRRQIFETFLALQQFGETKKGDQEVRRLCDE 2811
W + +WN E + S MD ++ F A+ G+ K + R D
Sbjct: 1364 AAAAWGLGQWNLISEYV-----SAMDRDPQDKEFFSAISAVH-LGQYNKAYGHIERHRDI 1417
Query: 2812 GIQ-LSLKKWHSLPKRYTPAHKA-LLHSFQQYMEFLEATQIYANLASTTVQNLDTKAQEI 2869
+ LS S + Y K+ +L ++ +++ + Q NL S
Sbjct: 1418 LVNDLSSIIGESYNRAYGIMVKSQMLSELEEIIDYKKNMQYENNLDS------------- 1464
Query: 2870 KRVLQAWRDRLPNIWDDITIWDDLVTWRQHVFNVINSAYLPLVPALQQANSNSNINTHAY 2929
+ + WR RL ++ +W + + +R V + +S + + A S+ ++
Sbjct: 1465 --LKKTWRKRLEGCQKNVDVWHNTLRFRALVLSPQDSPEMWIKLADLCRRSDRLKLSNQC 1522
Query: 2930 RGYHEIAWVINRFAHVARRHNMPDVCISQLARIYTLP--NIEIQEAFLKLREQAKCHYQN 2987
Y N + + + P V + L ++ NI + E + H
Sbjct: 1523 LTYLMGRDPSNAYPLDSLKLLNPHVVYTYLKYLWATDQKNIAVSELEEFTSYLSSKHGYK 1582
Query: 2988 MNELTTGLDVISNTNLVYFGTVQKAEFFTLKGMFLSKLRAHDEANQ--------AFATAV 3039
M + + +D+++++++ A F G + L+ D NQ + A
Sbjct: 1583 MGDSSKLVDILASSSVSSEERSFLARCFHKLGKWKKSLQ--DSVNQESVRDILNCYFYAT 1640
Query: 3040 QIDLNLAKAWAQWGFFNDRRLS---------EEPKNISFASNAMSCYLQAAGLYKNSKTR 3090
D + KAW W N + + + A+ + ++ L + + +
Sbjct: 1641 LFDKSWYKAWHSWALANFEVVGYYEQTEHGVTQDMYEQYIVPAIKGFFHSSVLNQKNSLQ 1700
Query: 3091 KLLSRILWLLGRDDSSNSLAYAFDSFRGEIPVWYWITFIPQLLTALSHKEAFL---VRKI 3147
+L R+L L + + +A A +P+ W+ IPQL+ + + + V ++
Sbjct: 1701 DIL-RLLNLWFKFGEHSDVAAAIVEGFSNVPMDTWLEVIPQLIARIHTSSSSVRASVHQL 1759
Query: 3148 LIRIAKSYPQALHFQLRTTKEDFAVIQRQSLALARTQGEPAETENQENSKHPSPDNSRTT 3207
L I + +PQAL + SL ++ P + + ++ +S T
Sbjct: 1760 LSDIGRVHPQALVY---------------SLTVSSKSTNPQQKHSAKSIMDSMLSHSDTL 1804
Query: 3208 SQNKSQDQDMYPNNRQPWEYLEELNGILKTAYPLLALSLESLVDQINQKFKTNPDEDLFR 3267
RQ +EL ++ A L E L + F D D+
Sbjct: 1805 V-------------RQALLVSQEL---IRVAILWHELWYEGLEEASQAYFS---DHDISL 1845
Query: 3268 LINVLLIDGTYNYNRLPYPREKPPLPSSTEANLIRFSENLLPP-NIRVKF--NADFIESK 3324
+I+++ L EK P S + F +L + KF + D E
Sbjct: 1846 MIDIV--------KPLHETLEKGPSTLSEISFAQTFGYDLRKARSYWQKFLQDGDPTELN 1897
Query: 3325 PDFEVYIKRLRFWRNRLENKLDRAPKVESMEAICPNLSNFHHQKFEDIKVPGQYLLNKDN 3384
+++Y + R R++ +L R +E ++ + P L + ++ VPG Y NK
Sbjct: 1898 QSWDLYYQVFR----RIQKQLPRIKHLE-LQYVSPKLLDACDL---ELAVPGTYGHNKP- 1948
Query: 3385 NTHFVKIGRFMPEVDFTRGTHTSHRRLTIRGHDGSLHSFAVQYPAVRHSRREERMFQLYR 3444
++I F + RRLTI G DG + + ++ R++ER+ QL+
Sbjct: 1949 ---VIRISHFHHTFEVISSKQRP-RRLTIHGSDGKDYQYVLK--GHEDLRQDERVMQLFG 2002
Query: 3445 LLNERLRKNVQTRRRDIQFTVPIAVPLSPQVRVMSDSASFRTLHQIYDEFCAKKNMDRDA 3504
L N L + +T +R + +PLSP ++ TLH + EF +K+N+
Sbjct: 2003 LCNTLLTTDSETFKRRLNIERYTVIPLSPNSGLLGWVPHSDTLHFLIKEFRSKRNI---- 2058
Query: 3505 IQDFITEQLNVAHDKVLP-PPDITAV----KVEIFSSIHSLFIPSTLLKDYYSKLF--SE 3557
LN+ H +L PD ++ K+E+F + + +T D Y L+ S
Sbjct: 2059 -------LLNLEHRMMLQMAPDCDSLTLLQKLEVFEYV----MANTDGYDLYHVLWLKSR 2107
Query: 3558 FEDFWLFRKQFASQYAAFVFMT-FMLSINNRSPHKIFVDEKSGNVHTLEMLPSRYSYERV 3616
+ WL R+ +Q A + M ++L + +R P + +D SG + ++
Sbjct: 2108 SSEAWLDRRTSYTQSLAVMSMVGYILGLGDRHPSNLMMDRYSGKIIHID----------- 2156
Query: 3617 NQYAKQFETNLPNSAPVFHNNEPVPFRMTPNIQKLIGDSAMEGVFSVGLFVIARALLEPD 3676
+ FE + E +PFR+T + + S ++G + + ++ R L
Sbjct: 2157 --FGDCFEVAMHRE----KFPEKIPFRLTRMLINAMEVSGIQGTYKITCELVMRVLRSNT 2210
Query: 3677 HELNTYLSLFIRDEVISW 3694
L L F+ D +I+W
Sbjct: 2211 ESLMAVLEAFVYDPLINW 2228
>SPBC216.07c [L] KOG0891 DNA-dependent protein kinase
Length = 1973
Score = 78.2 bits (191), Expect = 2e-13
Identities = 139/695 (20%), Positives = 268/695 (38%), Gaps = 126/695 (18%)
Query: 3029 DEANQAFATAVQIDLNLAKAWAQWGFFNDRR---LSEEPKNISFASNAMSCYLQAAGLYK 3085
D Q++ A Q D KAW W N L + + I A+ G +K
Sbjct: 1270 DGVLQSYMYATQFDSKWYKAWHSWALANFEAVKFLEQSEEQIPSAAYEQYIIPAVKGFFK 1329
Query: 3086 N--------SKTRKLLSRILWLLGRDDSS--NSLAYAFDSFRGEIPVWYWITFIPQLLTA 3135
+ T +LL+ LW ++S+ N+L + +I W+ IPQL+
Sbjct: 1330 SIALSKGNLQDTLRLLN--LWFKFGNNSNVINTLNVGISTVNIDI----WLDVIPQLIAR 1383
Query: 3136 LSHKEAFLVRKILIRIAKSYPQALHFQLRTTKEDFAVIQRQSLALARTQGEPAETENQEN 3195
+ H + VRK + ++ +A Q+L T +++ ++N
Sbjct: 1384 I-HASSLSVRKSVHQLLSDVGRA---------------HPQALVYPLTVAAKSQSSARQN 1427
Query: 3196 SKHPSPDNSRTTSQNKSQDQDMYPNNRQPWEYLEELNGILKTAYPLLALSLESLVDQINQ 3255
+ D+ +T S + + + +++ A E L +
Sbjct: 1428 AALAIMDSLKTHSPRLVEQARLVSHE------------LIRAAILWHEQWHEGLEEASRL 1475
Query: 3256 KFKTNPDEDLF---RLINVLLIDGTYNYNRLPYPREKPPLPSSTEANLIRFSENLLPPN- 3311
F + E +F R ++ +L G + + + F +L+
Sbjct: 1476 YFGDHNIEGMFAVLRPLHEMLERGPETLREISFQQA--------------FGRDLVEARD 1521
Query: 3312 --IRVKFNADFIESKPDFEVYIKRLRFWRNRLENKLDRAPKVESMEA--ICPNLSNFHHQ 3367
IR + D + +++Y + + R +L P++ +++ + P L + H
Sbjct: 1522 CCIRFEQTGDISDLNQAWDLYYQVFKKIRKQL-------PQLTTLDLQYVSPKLLHVHDL 1574
Query: 3368 KFEDIKVPGQYLLNKDNNTHFVKIGRFMPEVDFTRGTHTSHRRLTIRGHDGSLHSFAVQY 3427
++ VPG Y+ K ++I +F P + RRL+I+G DG + + ++
Sbjct: 1575 ---ELAVPGTYVSGKP----VIRIVKFYPTFNVITSKQRP-RRLSIKGSDGKDYQYVLK- 1625
Query: 3428 PAVRHSRREERMFQLYRLLNERLRKNVQTRRRDIQFTVPIAVPLSPQVRVMSDSASFRTL 3487
R++ER+ QL+ L N L + +T +R + +PLSP ++ TL
Sbjct: 1626 -GHEDIRQDERVMQLFGLCNNLLLADPETFKRLLSIQRYPVIPLSPDSGLLGWVLDSDTL 1684
Query: 3488 HQIYDEFCAKKNMDRDAIQDFITEQLNVAHDKVLP-PPDITAV----KVEIFSSIHSLFI 3542
H + ++ + + LN+ H ++ PD + KVE+F +
Sbjct: 1685 HVLIRDYRESRKI-----------LLNIEHRLIIQMAPDYDRLTLLQKVEVFEYA----L 1729
Query: 3543 PSTLLKDYYSKLF--SEFEDFWLFRKQFASQYAAFVFMT-FMLSINNRSPHKIFVDEKSG 3599
ST +D Y L+ S + WL R+ S+ A + M ++L + +R P + +D +G
Sbjct: 1730 LSTTGQDLYRVLWLKSRSSEAWLNRRTNYSRTLAVMSMVGYILGLGDRHPSNLMLDRYTG 1789
Query: 3600 NVHTLEMLPSRYSYERVNQYAKQFETNLPNSAPVFHNNEPVPFRMTPNIQKLIGDSAMEG 3659
N+ ++ V + ++F E +PFR+T + + S +EG
Sbjct: 1790 NIIHIDF----GDCFEVAMHREKFP-------------EKIPFRLTRMLVNAMEVSGIEG 1832
Query: 3660 VFSVGLFVIARALLEPDHELNTYLSLFIRDEVISW 3694
F + + R L + L F+ D +I+W
Sbjct: 1833 TFRITCEHVMRVLRTNKESVMAVLEAFVYDPLINW 1867
>SPBC216.05 [TBLD] KOG0890 Protein kinase of the PI-3 kinase family involved in
mitotic growth DNA repair and meiotic recombination
Length = 2386
Score = 69.7 bits (169), Expect = 9e-11
Identities = 85/402 (21%), Positives = 166/402 (41%), Gaps = 46/402 (11%)
Query: 3367 QKFEDIKVPGQYLLNKDNNTHFVK----IGRFMPEVDFTRGTHTSHRRLTIRGHDGSLHS 3422
+ F DI +P + N+ ++ F K + +F EVD R++ +RG DG+L+
Sbjct: 2022 KSFLDITLPAKDA-NRASHYPFPKTQPTLLKFEDEVDIMNSLQKP-RKVYVRGTDGNLYP 2079
Query: 3423 FAVQYPAVRHSRREERMFQLYRLLNERLRKNVQTRRRDIQFTVPIAVPLSPQVRVMSDSA 3482
F + R++ R+ + L+ + LRK+ + RR++ + +PL+ + +
Sbjct: 2080 FLCK--PKDDLRKDARLMEFNNLICKILRKDQEANRRNLCIRTYVVIPLNEECGFIEWVN 2137
Query: 3483 SFRTLHQIYDEFCAKKNMDRDAIQDFITEQLNVAHDKVLPPPDITAVKVEIFSS-IHSLF 3541
R +I + +KN+ +++ V D L P+ +IF I F
Sbjct: 2138 HTRPFREILLKSYRQKNIP------ISYQEIKVDLDFALRSPN----PGDIFEKKILPKF 2187
Query: 3542 IPSTLLKDYYSKLFSEFEDFWLFRKQFASQYAAFVFMTFMLSINNRSPHKIFVDEKSGNV 3601
P + +++ + F E ++ R+ + A + ++L + +R I DE +G
Sbjct: 2188 PP--VFYEWFVESFPEPNNWVTSRQNYCRTLAVMSIVGYVLGLGDRHGENILFDEFTGEA 2245
Query: 3602 HTLEMLPSRYSYERVNQYAKQFETNLPNSAPVFHNNEPVPFRMTPNIQKLIGDSAMEGVF 3661
++ + F+ L F E VPFR+T N+ +G + EG F
Sbjct: 2246 IHVD-------------FNCLFDKGL-----TFEKPEKVPFRLTHNMVDAMGPTGYEGGF 2287
Query: 3662 SVGLFVIARALLEPDHELNTYLSLFIRDEVISWYSSMNRSIVEDPHLYAIVLTNVDLIIR 3721
+ R L L + L F+ D ++ W + S + + +D+I +
Sbjct: 2288 RKASEITMRLLRSNQDTLMSVLESFLHDPLVEWNRKKSSSKYPNNEANEV----LDIIRK 2343
Query: 3722 KVAQFGHMSSSPSVATQYVLDAISAAVSPRNLAKCDQSFMAW 3763
K F + P + + I +AV+P+NL + ++ W
Sbjct: 2344 KFQGFMPGETIPLSIEGQIQELIKSAVNPKNLV---EMYIGW 2382
>CE28813 [L] KOG0891 DNA-dependent protein kinase
Length = 687
Score = 67.4 bits (163), Expect = 4e-10
Identities = 104/464 (22%), Positives = 190/464 (40%), Gaps = 74/464 (15%)
Query: 3327 FEVYIKRLRFWRNRLE--NKLDRAPKVESMEAICPNLSNFHHQKFEDIKVPGQYLLNKDN 3384
+E+Y + R++L N LD + + PNL + K ++ VPG Y D
Sbjct: 267 WEIYCSVFKKLRDQLATLNSLD-------LVYVSPNLVS---AKDLELVVPGTY----DP 312
Query: 3385 NTHFVKIGRFMPEVDFTRGTHTSHRRLTIRGHDGSLHSFAVQYPAVRHSRREERMFQLYR 3444
+ V I F +++ R++ IRG +G + F ++ R++ER+ QL+
Sbjct: 313 SAPIVSIQSFSSKMNVITSKQRP-RKMVIRGSNGLDYQFLLK--GHEDPRQDERVMQLFG 369
Query: 3445 LLNERLRKNVQTRRRDIQFTVPIAVPLSPQVRVMSDSASFRTLHQIYDEFCAKKNMDRDA 3504
L+N L N +T RR++ V LS ++ + TLH + E+ KK +
Sbjct: 370 LVNTLLANNSETCRRNLTIQRYSIVALSKDSGLIGWVPNCDTLHTLVKEYREKKAKIPLS 429
Query: 3505 IQDFITEQLNVAHDKVLPPPDITAVKVEIFSSIHSLFIPSTLLKDYYSKLFSEFEDFWLF 3564
I+ ++L++ + + K+++F S S+ L + K S + W
Sbjct: 430 IEHKTLQKLSLETEHL-----TLMQKLQLFESALSVTQGEDLRHVLWLK--SPSSEVWFD 482
Query: 3565 RK-QFASQYAAFVFMTFMLSINNRSPHKIFVDEKSGNVHTLEMLPSRYSYERVNQYAKQF 3623
R+ + A + ++L + +R P + +D +G V ++ + F
Sbjct: 483 RRTNYTRSVACMSMVGYILGLGDRHPSNLMLDRLTGKVVHID-------------FGDCF 529
Query: 3624 E-TNLPNSAPVFHNNEPVPFRMTPNIQKLIGDSAMEGVFSVGLFVIARALLEPDHELNTY 3682
E L P E VPFR+T + + + ++GV++ + + L L
Sbjct: 530 EVAMLREKFP-----ERVPFRLTRMLINAMEVTGLDGVYNYTAERVLKMLRTNQESLLAV 584
Query: 3683 LSLFIRDEVISWYSSMNRSIVEDP----------HLYAIVLTN-------VDLIIRKV-- 3723
L F+ D VI+W + + +DP ++ VL + ++ I RK+
Sbjct: 585 LEAFVYDPVINW--RLVEGMKKDPKTRKDTGGRQNMAGAVLPSSSTTDSIMETIKRKLDG 642
Query: 3724 AQFGHMSSS----PSVATQYVLDAISAAVSPRNLAKCDQSFMAW 3763
+F H S P T+ + A SP NL QS++ W
Sbjct: 643 TEFVHTDGSTPPEPLQVTEQLAMLTEQATSPLNLC---QSYIGW 683
>CE07705 [L] KOG0891 DNA-dependent protein kinase
Length = 2697
Score = 67.4 bits (163), Expect = 4e-10
Identities = 104/464 (22%), Positives = 190/464 (40%), Gaps = 74/464 (15%)
Query: 3327 FEVYIKRLRFWRNRLE--NKLDRAPKVESMEAICPNLSNFHHQKFEDIKVPGQYLLNKDN 3384
+E+Y + R++L N LD + + PNL + K ++ VPG Y D
Sbjct: 2277 WEIYCSVFKKLRDQLATLNSLD-------LVYVSPNLVS---AKDLELVVPGTY----DP 2322
Query: 3385 NTHFVKIGRFMPEVDFTRGTHTSHRRLTIRGHDGSLHSFAVQYPAVRHSRREERMFQLYR 3444
+ V I F +++ R++ IRG +G + F ++ R++ER+ QL+
Sbjct: 2323 SAPIVSIQSFSSKMNVITSKQRP-RKMVIRGSNGLDYQFLLK--GHEDPRQDERVMQLFG 2379
Query: 3445 LLNERLRKNVQTRRRDIQFTVPIAVPLSPQVRVMSDSASFRTLHQIYDEFCAKKNMDRDA 3504
L+N L N +T RR++ V LS ++ + TLH + E+ KK +
Sbjct: 2380 LVNTLLANNSETCRRNLTIQRYSIVALSKDSGLIGWVPNCDTLHTLVKEYREKKAKIPLS 2439
Query: 3505 IQDFITEQLNVAHDKVLPPPDITAVKVEIFSSIHSLFIPSTLLKDYYSKLFSEFEDFWLF 3564
I+ ++L++ + + K+++F S S+ L + K S + W
Sbjct: 2440 IEHKTLQKLSLETEHL-----TLMQKLQLFESALSVTQGEDLRHVLWLK--SPSSEVWFD 2492
Query: 3565 RK-QFASQYAAFVFMTFMLSINNRSPHKIFVDEKSGNVHTLEMLPSRYSYERVNQYAKQF 3623
R+ + A + ++L + +R P + +D +G V ++ + F
Sbjct: 2493 RRTNYTRSVACMSMVGYILGLGDRHPSNLMLDRLTGKVVHID-------------FGDCF 2539
Query: 3624 E-TNLPNSAPVFHNNEPVPFRMTPNIQKLIGDSAMEGVFSVGLFVIARALLEPDHELNTY 3682
E L P E VPFR+T + + + ++GV++ + + L L
Sbjct: 2540 EVAMLREKFP-----ERVPFRLTRMLINAMEVTGLDGVYNYTAERVLKMLRTNQESLLAV 2594
Query: 3683 LSLFIRDEVISWYSSMNRSIVEDP----------HLYAIVLTN-------VDLIIRKV-- 3723
L F+ D VI+W + + +DP ++ VL + ++ I RK+
Sbjct: 2595 LEAFVYDPVINW--RLVEGMKKDPKTRKDTGGRQNMAGAVLPSSSTTDSIMETIKRKLDG 2652
Query: 3724 AQFGHMSSS----PSVATQYVLDAISAAVSPRNLAKCDQSFMAW 3763
+F H S P T+ + A SP NL QS++ W
Sbjct: 2653 TEFVHTDGSTPPEPLQVTEQLAMLTEQATSPLNLC---QSYIGW 2693
>YKL203c [L] KOG0891 DNA-dependent protein kinase
Length = 2473
Score = 67.0 bits (162), Expect = 6e-10
Identities = 82/363 (22%), Positives = 156/363 (42%), Gaps = 43/363 (11%)
Query: 3349 PKVESMEA--ICPNLSNFHHQKFEDIKVPGQYLLNKDNNTHFVKIGRFMPEVDFTRGTHT 3406
P+++++E + P L + H ++ VPG VKI +F P V +
Sbjct: 2055 PQLQTLELQHVSPKLLSAHDL---ELAVPGT---RASGGKPIVKISKFEP-VFSVISSKQ 2107
Query: 3407 SHRRLTIRGHDGSLHSFAVQYPAVRHSRREERMFQLYRLLNERLRKNVQTRRRDIQFTVP 3466
R+ I+G DG + + ++ R++ + QL+ L+N L+ + + RR +
Sbjct: 2108 RPRKFCIKGSDGKDYKYVLK--GHEDIRQDSLVMQLFGLVNTLLQNDAECFRRHLDIQQY 2165
Query: 3467 IAVPLSPQVRVMSDSASFRTLHQIYDEFCAKKNMDRDAIQDFITEQLNVAHDKVLPPPDI 3526
A+PLSP+ ++ + T H + E K + + I+ ++ Q+ +D +
Sbjct: 2166 PAIPLSPKSGLLGWVPNSDTFHVLIREHREAKKIPLN-IEHWVMLQMAPDYDNLT----- 2219
Query: 3527 TAVKVEIFSSIHSLFIPSTLLKDYYSKLF--SEFEDFWLFRKQFASQYAAFVFMT-FMLS 3583
KVE+F+ + +T +D Y L+ S + WL R+ ++ A + MT ++L
Sbjct: 2220 LLQKVEVFTYA----LNNTEGQDLYKVLWLKSRSSETWLERRTTYTRSLAVMSMTGYILG 2275
Query: 3584 INNRSPHKIFVDEKSGNVHTLEMLPSRYSYERVNQYAKQFETN-LPNSAPVFHNNEPVPF 3642
+ +R P + +D +G V ++ + FE L P E VPF
Sbjct: 2276 LGDRHPSNLMLDRITGKVIHID-------------FGDCFEAAILREKFP-----EKVPF 2317
Query: 3643 RMTPNIQKLIGDSAMEGVFSVGLFVIARALLEPDHELNTYLSLFIRDEVISWYSSMNRSI 3702
R+T + + S +EG F + + + L + L L F D +I+W +
Sbjct: 2318 RLTRMLTYAMEVSGIEGSFRITCENVMKVLRDNKGSLMAILEAFAFDPLINWGFDLPTKK 2377
Query: 3703 VED 3705
+E+
Sbjct: 2378 IEE 2380
>YJR066w [L] KOG0891 DNA-dependent protein kinase
Length = 2470
Score = 66.2 bits (160), Expect = 9e-10
Identities = 80/362 (22%), Positives = 149/362 (41%), Gaps = 47/362 (12%)
Query: 3371 DIKVPGQYLLNKDNNTHFVKIGRFMPEVDFTRGTHTSHRRLTIRGHDGSLHSFAVQYPAV 3430
++ VPG Y K ++I +F P R+ +I+G DG + + ++
Sbjct: 2074 ELAVPGTYFPGKPT----IRIAKFEPLFSVISSKQRP-RKFSIKGSDGKDYKYVLK--GH 2126
Query: 3431 RHSRREERMFQLYRLLNERLRKNVQTRRRDIQFTVPIAVPLSPQVRVMSDSASFRTLHQI 3490
R++ + QL+ L+N L+ + + +R + A+PLSP+ ++ + T H +
Sbjct: 2127 EDIRQDSLVMQLFGLVNTLLKNDSECFKRHLDIQQYPAIPLSPKSGLLGWVPNSDTFHVL 2186
Query: 3491 YDEFCAKKNMDRDAIQDFITEQLNVAHDKVLP-PPDITAV----KVEIFSSIHSLFIPST 3545
E K + LN+ H +L PD + K+E+F+ + +T
Sbjct: 2187 IREHRDAKKIP-----------LNIEHWVMLQMAPDYENLTLLQKIEVFTYA----LDNT 2231
Query: 3546 LLKDYYSKLF--SEFEDFWLFRKQFASQYAAFVFMT-FMLSINNRSPHKIFVDEKSGNVH 3602
+D Y L+ S + WL R+ ++ A + MT ++L + +R P + +D +G V
Sbjct: 2232 KGQDLYKILWLKSRSSETWLERRTTYTRSLAVMSMTGYILGLGDRHPSNLMLDRITGKVI 2291
Query: 3603 TLEMLPSRYSYERVNQYAKQFETNLPNSAPVFHNNEPVPFRMTPNIQKLIGDSAMEGVFS 3662
++ + FE + E VPFR+T + + S +EG F
Sbjct: 2292 HID-------------FGDCFEAAILREK----YPEKVPFRLTRMLTYAMEVSGIEGSFR 2334
Query: 3663 VGLFVIARALLEPDHELNTYLSLFIRDEVISWYSSMNRSIVEDPHLYAIVLTNVDLIIRK 3722
+ + R L + L L F D +I W + + + + L N ++RK
Sbjct: 2335 ITCENVMRVLRDNKESLMAILEAFALDPLIHWGFDLPPQKLTEQTGIPLPLINPSELLRK 2394
Query: 3723 VA 3724
A
Sbjct: 2395 GA 2396
>Hs4826730 [L] KOG0891 DNA-dependent protein kinase
Length = 2549
Score = 65.9 bits (159), Expect = 1e-09
Identities = 69/330 (20%), Positives = 130/330 (38%), Gaps = 43/330 (13%)
Query: 3371 DIKVPGQYLLNKDNNTHFVKIGRFMPEVDFTRGTHTSHRRLTIRGHDGSLHSFAVQYPAV 3430
++ VPG Y D N ++I P + R+LT+ G +G H F
Sbjct: 2137 ELAVPGTY----DPNQPIIRIQSIAPSLQVITSKQRP-RKLTLMGSNG--HEFVFLLKGH 2189
Query: 3431 RHSRREERMFQLYRLLNERLRKNVQTRRRDIQFTVPIAVPLSPQVRVMSDSASFRTLHQI 3490
R++ER+ QL+ L+N L + + R+++ +PLS ++ TLH +
Sbjct: 2190 EDLRQDERVMQLFGLVNTLLANDPTSLRKNLSIQRYAVIPLSTNSGLIGWVPHCDTLHAL 2249
Query: 3491 YDEFCAKKNMDRDAIQDFITEQLNVAHDKVL-PPPDITAV----KVEIFSSIHSLFIPST 3545
++ KK + LN+ H +L PD + KVE+F +
Sbjct: 2250 IRDYREKKKI-----------LLNIEHRIMLRMAPDYDHLTLMQKVEVFEHAVNNTAGDD 2298
Query: 3546 LLKDYYSKLFSEFEDFWLFRK-QFASQYAAFVFMTFMLSINNRSPHKIFVDEKSGNVHTL 3604
L K + K S + W R+ + A + ++L + +R P + +D SG + +
Sbjct: 2299 LAKLLWLK--SPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHI 2356
Query: 3605 EMLPSRYSYERVNQYAKQFETNLPNSAPVFHNNEPVPFRMTPNIQKLIGDSAMEGVFSVG 3664
+ + FE + E +PFR+T + + + ++G + +
Sbjct: 2357 D-------------FGDCFEVAMTRE----KFPEKIPFRLTRMLTNAMEVTGLDGNYRIT 2399
Query: 3665 LFVIARALLEPDHELNTYLSLFIRDEVISW 3694
+ L E + L F+ D +++W
Sbjct: 2400 CHTVMEVLREHKDSVMAVLEAFVYDPLLNW 2429
>At5g40820 [TBLD] KOG0890 Protein kinase of the PI-3 kinase family involved in
mitotic growth DNA repair and meiotic recombination
Length = 2810
Score = 59.7 bits (143), Expect = 9e-08
Identities = 79/364 (21%), Positives = 143/364 (38%), Gaps = 49/364 (13%)
Query: 3409 RRLTIRGHDGSLHSFAVQYPAVRHS----RREERMFQLYRLLNERLRKNVQTRRRDIQFT 3464
+++ + G+DG ++YP + R++ RM + ++N L K ++RRR +
Sbjct: 2381 KKIILLGNDG------IEYPFLCKPKDDLRKDARMMEFTAMINRLLSKYPESRRRKLYIR 2434
Query: 3465 VPIAVPLSPQVRVMSDSASFRTL-HQIYDEFCAKKNMDRDAIQDFITEQLNVAHDKVLPP 3523
PL+ ++ R L H + D + + DR Q+ +D+
Sbjct: 2435 TFAVAPLTEDCGLVEWVPHTRGLRHILQDIYISCGKFDRQKTNP----QIKRIYDQCAVK 2490
Query: 3524 PDITAVKVEIFSSIHSLFIPSTLLKDYYSKLFSEFEDFWLFRKQFASQYAAFVFMTFMLS 3583
+ +K +I +F ++ FSE ++ R +A A + + ++
Sbjct: 2491 KEYEMLKTKILPMFPPVF------HKWFLTTFSEPAAWFRSRVAYAHTTAVWSMVGHIVG 2544
Query: 3584 INNRSPHKIFVDEKSGN-VHTLEMLPSRYSYERVNQYAKQFETNLPNSAPVFHNNEPVPF 3642
+ +R I D SG+ VH ++ F+ L P E VPF
Sbjct: 2545 LGDRHGENILFDSTSGDCVHV--------------DFSCLFDKGLQLEKP-----ELVPF 2585
Query: 3643 RMTPNIQKLIGDSAMEGVFSVGLFVIARALLEPDHELNTYLSLFIRDEVISWYSSMNRSI 3702
R+T N+ +G + EG+F + L L + L FI D ++ W S S
Sbjct: 2586 RLTQNMIDGLGITGYEGIFMRVCEITLTVLRTHRETLMSILETFIHDPLVEWTKSHKSSG 2645
Query: 3703 VE--DPHLYAIVLTNVDLIIRKVAQFGHMSSSPSVATQYVLDAISAAVSPRNLAKCDQSF 3760
VE +PH +++++ ++ G + P I+ AVS NL K +
Sbjct: 2646 VEVQNPHAQR-AISSIEARLQ-----GVVVGVPLPVEGQARRLIADAVSLENLGKMYIWW 2699
Query: 3761 MAWL 3764
M WL
Sbjct: 2700 MPWL 2703
>Hs4502325 [TBLD] KOG0890 Protein kinase of the PI-3 kinase family involved in
mitotic growth DNA repair and meiotic recombination
Length = 2644
Score = 58.2 bits (139), Expect = 3e-07
Identities = 53/288 (18%), Positives = 117/288 (40%), Gaps = 34/288 (11%)
Query: 3409 RRLTIRGHDGSLHSFAVQYPAVRHSRREERMFQLYRLLNERLRKNVQTRRRDIQFTVPIA 3468
++++++G DG + + R++ R+ + L+N+ LRK+ ++RRR++
Sbjct: 2310 KKISLKGSDGKF--YIMMCKPKDDLRKDCRLMEFNSLINKCLRKDAESRRRELHIRTYAV 2367
Query: 3469 VPLSPQVRVMSDSASFRTLHQIYDEFCAKKNMDRDAIQDFITEQLNVAHDKVLPPPDITA 3528
+PL+ + ++ + L I + +K + ++T + +LP +
Sbjct: 2368 IPLNDECGIIEWVNNTAGLRPILTKLYKEKGV-------YMTGK--ELRQCMLPKSAALS 2418
Query: 3529 VKVEIFSSIHSLFIPS--TLLKDYYSKLFSEFEDFWLFRKQFASQYAAFVFMTFMLSINN 3586
K+++F +P + +++ + F + ++ R + A + ++L + +
Sbjct: 2419 EKLKVF---REFLLPRHPPIFHEWFLRTFPDPTSWYSSRSAYCRSTAVMSMVGYILGLGD 2475
Query: 3587 RSPHKIFVDEKSGNVHTLEMLPSRYSYERVNQYAKQFETNLPNSAPVFHNNEPVPFRMTP 3646
R I D +G ++ L N F E VPFR+T
Sbjct: 2476 RHGENILFDSLTGECVHVDF------------------NCLFNKGETFEVPEIVPFRLTH 2517
Query: 3647 NIQKLIGDSAMEGVFSVGLFVIARALLEPDHELNTYLSLFIRDEVISW 3694
N+ +G EG+F V R + + L + L F+ D ++ W
Sbjct: 2518 NMVNGMGPMGTEGLFRRACEVTMRLMRDQREPLMSVLKTFLHDPLVEW 2565
>Hs22041606 [TBLD] KOG0890 Protein kinase of the PI-3 kinase family involved in
mitotic growth DNA repair and meiotic recombination
Length = 1212
Score = 58.2 bits (139), Expect = 3e-07
Identities = 53/288 (18%), Positives = 117/288 (40%), Gaps = 34/288 (11%)
Query: 3409 RRLTIRGHDGSLHSFAVQYPAVRHSRREERMFQLYRLLNERLRKNVQTRRRDIQFTVPIA 3468
++++++G DG + + R++ R+ + L+N+ LRK+ ++RRR++
Sbjct: 878 KKISLKGSDGKF--YIMMCKPKDDLRKDCRLMEFNSLINKCLRKDAESRRRELHIRTYAV 935
Query: 3469 VPLSPQVRVMSDSASFRTLHQIYDEFCAKKNMDRDAIQDFITEQLNVAHDKVLPPPDITA 3528
+PL+ + ++ + L I + +K + ++T + +LP +
Sbjct: 936 IPLNDECGIIEWVNNTAGLRPILTKLYKEKGV-------YMTGK--ELRQCMLPKSAALS 986
Query: 3529 VKVEIFSSIHSLFIPS--TLLKDYYSKLFSEFEDFWLFRKQFASQYAAFVFMTFMLSINN 3586
K+++F +P + +++ + F + ++ R + A + ++L + +
Sbjct: 987 EKLKVF---REFLLPRHPPIFHEWFLRTFPDPTSWYSSRSAYCRSTAVMSMVGYILGLGD 1043
Query: 3587 RSPHKIFVDEKSGNVHTLEMLPSRYSYERVNQYAKQFETNLPNSAPVFHNNEPVPFRMTP 3646
R I D +G ++ L N F E VPFR+T
Sbjct: 1044 RHGENILFDSLTGECVHVDF------------------NCLFNKGETFEVPEIVPFRLTH 1085
Query: 3647 NIQKLIGDSAMEGVFSVGLFVIARALLEPDHELNTYLSLFIRDEVISW 3694
N+ +G EG+F V R + + L + L F+ D ++ W
Sbjct: 1086 NMVNGMGPMGTEGLFRRACEVTMRLMRDQREPLMSVLKTFLHDPLVEW 1133
>7297995 [L] KOG0891 DNA-dependent protein kinase
Length = 2470
Score = 57.0 bits (136), Expect = 6e-07
Identities = 64/292 (21%), Positives = 116/292 (38%), Gaps = 38/292 (13%)
Query: 3409 RRLTIRGHDGSLHSFAVQYPAVRHSRREERMFQLYRLLNERLRKNVQTRRRDIQFTVPIA 3468
R+L IRG +G + + ++ R++ER+ QL+ L+N L + T RR++
Sbjct: 2091 RKLCIRGSNGKDYMYLLK--GHEDLRQDERVMQLFSLVNTLLLDDPDTFRRNLAIQRYAV 2148
Query: 3469 VPLSPQVRVMSDSASFRTLHQIYDEFCAKKNMDRDAIQDFITEQLNVAHDKVLP-PPDIT 3527
+PLS ++ TLH + ++ KK + LN H +L PD
Sbjct: 2149 IPLSTNSGLIGWVPHCDTLHTLIRDYRDKKKV-----------PLNQEHRTMLNFAPDYD 2197
Query: 3528 AV----KVEIFSSIHSLFIPSTLLKDYYSKLFSEFEDFWLFRK-QFASQYAAFVFMTFML 3582
+ KVE+F L K + K S + W R+ + A + ++L
Sbjct: 2198 HLTLMQKVEVFEHALGQTQGDDLAKLLWLK--SPSSELWFERRNNYTRSLAVMSMVGYIL 2255
Query: 3583 SINNRSPHKIFVDEKSGNVHTLEMLPSRYSYERVNQYAKQFETNLPNSAPVFHNNEPVPF 3642
+ +R P + +D SG + ++ + FE + E +PF
Sbjct: 2256 GLGDRHPSNLMLDRMSGKILHID-------------FGDCFEVAMTRE----KFPEKIPF 2298
Query: 3643 RMTPNIQKLIGDSAMEGVFSVGLFVIARALLEPDHELNTYLSLFIRDEVISW 3694
R+T + K + + +EG + + L L L F+ D +++W
Sbjct: 2299 RLTRMLIKAMEVTGIEGTYRRTCESVMLVLRRNKDSLMAVLEAFVYDPLLNW 2350
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.321 0.136 0.392
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 214,410,287
Number of Sequences: 60738
Number of extensions: 9243833
Number of successful extensions: 27384
Number of sequences better than 1.0e-05: 20
Number of HSP's better than 0.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 27087
Number of HSP's gapped (non-prelim): 123
length of query: 3764
length of database: 30,389,216
effective HSP length: 126
effective length of query: 3638
effective length of database: 22,736,228
effective search space: 82714397464
effective search space used: 82714397464
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)