ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI5963 good V KOG4003 Defense mechanisms Pyrazinamidase/nicotinamidase PNC1
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI5963 2080118 2079465 -218
(218 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YGL037c [V] KOG4003 Pyrazinamidase/nicotinamidase PNC1 219 3e-57
7300541 [V] KOG4003 Pyrazinamidase/nicotinamidase PNC1 114 8e-26
CE27609 [V] KOG4003 Pyrazinamidase/nicotinamidase PNC1 107 2e-23
SPBC557.06c [V] KOG4003 Pyrazinamidase/nicotinamidase PNC1 87 2e-17
>YGL037c [V] KOG4003 Pyrazinamidase/nicotinamidase PNC1
Length = 216
Score = 219 bits (557), Expect = 3e-57
Identities = 98/214 (45%), Positives = 153/214 (70%), Gaps = 5/214 (2%)
Query: 4 RALLVIDIQNDFLPPKGSLAVQDGDTIIDPVIQLLQD--QDWDCVAMTKDWHPPDHISFA 61
+ L+V+D+QNDF+ P GSL V G+ +I+P+ L+QD +DW + +T+DWHP HISFA
Sbjct: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
Query: 62 KNHGLPD-FSSFTYDSPVPGSTEKQSATLWPVHCVQETWGSEVPEKLLAEILKLKVPHKI 120
KNH + +S++TY SP PG Q LWPVHCV+ TWGS++ ++++ +++ + KI
Sbjct: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHI--KI 119
Query: 121 VNKGYLSDREYYSGFNDIWNDHHTELDAFFKENDVTEIYVVGLAFDFCVKNSAISAANLG 180
V+KG+L+DREYYS F+DIWN H T+++ + +++ E+Y+VG+A ++CVK +AISAA LG
Sbjct: 120 VDKGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELG 179
Query: 181 YHVTILKDYTKAIANDLQSIESFIQELAKNEVSV 214
Y T+L DYT+ I++D + I +EL + ++V
Sbjct: 180 YKTTVLLDYTRPISDDPEVINKVKEELKAHNINV 213
>7300541 [V] KOG4003 Pyrazinamidase/nicotinamidase PNC1
Length = 328
Score = 114 bits (286), Expect = 8e-26
Identities = 75/213 (35%), Positives = 107/213 (50%), Gaps = 26/213 (12%)
Query: 5 ALLVIDIQNDFLPPKGSL------AVQDGDTIIDPVIQLLQDQDWDCVAMTKDWHPPDHI 58
A L++D+QNDF+ GSL A Q G I++P+ +LL D+D V + DWHP DH+
Sbjct: 69 AFLIVDVQNDFI--SGSLDISNCSAQQQGHEILEPINKLLDTVDFDAVFYSLDWHPSDHV 126
Query: 59 SFAKN---------HGLPDFSSFTYDSPVPGSTEKQSATLWPVHCVQETWGSEVPEKLLA 109
SF N L S+ +D+ + LWP HCVQ++WG+E+ + L
Sbjct: 127 SFIDNVKMRPMDESSALDSDSAKVFDTVIFAGPPPMKQRLWPRHCVQDSWGAELHKDLKV 186
Query: 110 EILKLKVPHKI-VNKGYLSDREYYSGFNDIWNDHHTELDAFFKENDVTEIYVVGLAFDFC 168
V H I V KG + + YS F D T L+A K T+IYV GLA+D C
Sbjct: 187 ------VDHGIKVYKGTNPEVDSYSVFWDNKKLSDTTLNAQLKMKGATDIYVCGLAYDVC 240
Query: 169 VKNSAISAANLGYHVTILKDYTKAIANDLQSIE 201
V +A+ A + GY ++ D + D+ IE
Sbjct: 241 VGATAVDALSAGYRTILIDDCCR--GTDVHDIE 271
>CE27609 [V] KOG4003 Pyrazinamidase/nicotinamidase PNC1
Length = 335
Score = 107 bits (266), Expect = 2e-23
Identities = 67/205 (32%), Positives = 102/205 (49%), Gaps = 34/205 (16%)
Query: 5 ALLVIDIQNDFLPPKGSLAVQDGD------TIIDPVIQLLQDQDWDCVAMTKDWHPPDHI 58
ALLV+D QNDF+ GSL + DGD + I P+ +LLQ WD V TKDWHP +HI
Sbjct: 94 ALLVVDFQNDFVD--GSLKIGDGDAGQEPSSAITPLNELLQLSSWDLVVYTKDWHPHNHI 151
Query: 59 SFA--------------KNHGLPDFSSFTYDSPVPGSTEKQSATLWPVHCVQETWGSEV- 103
SF +N L F S + P+ K L+P HC+Q++WGS++
Sbjct: 152 SFLSQAHNSDRVMDEKDENKTLGFFDSVQFLKPI-----KTEQVLYPDHCIQKSWGSDIH 206
Query: 104 PEKLLAEILKLKVPHKIVNKGYLSDREYYSGFNDIWNDHHTELDAFFKENDVTEIYVVGL 163
PE +A+ + + KG + YS FND TEL+ + ++ + + GL
Sbjct: 207 PEIYIAD------NAEYIMKGVDPYLDSYSAFNDNNGRSKTELEDLLRRENIDAVVIAGL 260
Query: 164 AFDFCVKNSAISAANLGYHVTILKD 188
A+D CV+ + + A + ++ +
Sbjct: 261 AYDICVRFTCLDAVKQNFLAAVIPE 285
>SPBC557.06c [V] KOG4003 Pyrazinamidase/nicotinamidase PNC1
Length = 198
Score = 86.7 bits (213), Expect = 2e-17
Identities = 65/179 (36%), Positives = 93/179 (51%), Gaps = 20/179 (11%)
Query: 33 PVIQLLQDQD--WDCVAMTKDWHPPDHISFAKNH-GLPDFSSFTYDSPVPGSTEKQSATL 89
PVI L + D WD V TKD HP DH+SF +H P S + G KQ TL
Sbjct: 11 PVINRLLENDYKWDTVIATKDVHPKDHLSFTTSHSSTPKPSGTVVNIEAYGHVYKQ--TL 68
Query: 90 WPVHCVQETWGSEVPEKLLAEILKLKVPHKIVNKGYLSDR--EYYSGFND-IWNDHHTEL 146
W HCV+ T G E P+ L + ++ +P KG SDR E YSGF D I D+ L
Sbjct: 69 WNSHCVENTPGCEFPDSLNGDRIEFVIP-----KG--SDRLVESYSGFYDAIGRDN--GL 119
Query: 147 DAFFKENDVTEIYVVGLAFDFCVKNSAISAANLGYHVTILKDYTKAIANDL--QSIESF 203
A + +T++++ G+A D CVK +A+ A + Y+ I+ + K + + Q+I+ F
Sbjct: 120 KAILDKKGITDVFIAGVATDICVKETALHARH-WYNTYIISEAVKGSSTESHNQAIKDF 177
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.318 0.136 0.413
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,847,004
Number of Sequences: 60738
Number of extensions: 607789
Number of successful extensions: 1368
Number of sequences better than 1.0e-05: 4
Number of HSP's better than 0.0 without gapping: 1
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 1356
Number of HSP's gapped (non-prelim): 4
length of query: 218
length of database: 30,389,216
effective HSP length: 102
effective length of query: 116
effective length of database: 24,193,940
effective search space: 2806497040
effective search space used: 2806497040
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)