ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI5974 check: MH T KOG0671 Signal transduction mechanisms LAMMER dual specificity kinases
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI5974 2085547 2083451 -699
(699 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YLL019c [T] KOG0671 LAMMER dual specificity kinases 680 0.0
SPAC1D4.11c [T] KOG0671 LAMMER dual specificity kinases 299 9e-81
At3g53570 [T] KOG0671 LAMMER dual specificity kinases 260 6e-69
Hs4758008 [T] KOG0671 LAMMER dual specificity kinases 257 4e-68
Hs22045050 [T] KOG0671 LAMMER dual specificity kinases 257 4e-68
At4g24740 [T] KOG0671 LAMMER dual specificity kinases 253 7e-67
CE05549 [T] KOG0671 LAMMER dual specificity kinases 246 9e-65
At4g32660 [T] KOG0671 LAMMER dual specificity kinases 244 2e-64
7301719 [T] KOG0671 LAMMER dual specificity kinases 242 2e-63
Hs10190706 [T] KOG0671 LAMMER dual specificity kinases 239 8e-63
Hs4502883_2 [T] KOG0671 LAMMER dual specificity kinases 232 2e-60
Hs4502885_2 [T] KOG0671 LAMMER dual specificity kinases 229 8e-60
SPAC2F7.03c [R] KOG0667 Dual-specificity tyrosine-phosphorylatio... 169 1e-41
Hs4503429 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 154 6e-37
Hs20550209 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 152 2e-36
Hs5922004 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 145 2e-34
Hs4503427 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 145 2e-34
7298142 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 143 8e-34
ECU11g0180 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 141 4e-33
Hs13430860 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 140 9e-33
YJL141c [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 139 1e-32
CE23751 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 139 1e-32
CE19878 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 139 1e-32
CE05897 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 139 1e-32
At3g53640 [A] KOG0670 U4/U6-associated splicing factor PRP4 139 1e-32
7291976 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 139 2e-32
Hs5922001 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 138 3e-32
Hs5921999 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 138 3e-32
Hs4758222 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 138 3e-32
CE04430 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 135 2e-31
Hs11386209 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 135 2e-31
CE05686 [A] KOG0670 U4/U6-associated splicing factor PRP4 135 3e-31
Hs18765758 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 134 6e-31
Hs18765756 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 134 6e-31
Hs18765754 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 134 6e-31
Hs18765752 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 134 6e-31
Hs18765750 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 134 6e-31
At1g13350 [A] KOG0670 U4/U6-associated splicing factor PRP4 132 2e-30
At3g17750 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 131 4e-30
At1g73460 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 131 4e-30
At2g40120 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 129 1e-29
At1g73450 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 129 2e-29
Hs17999535 [A] KOG0670 U4/U6-associated splicing factor PRP4 128 3e-29
CE06352 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 127 4e-29
At5g35980 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 126 1e-28
At3g25840 [A] KOG0670 U4/U6-associated splicing factor PRP4 125 2e-28
SPAC1E11.03 [R] KOG0667 Dual-specificity tyrosine-phosphorylatio... 124 4e-28
At4g35500 [T] KOG1290 Serine/threonine protein kinase 122 2e-27
At2g17530 [T] KOG1290 Serine/threonine protein kinase 121 4e-27
7291932 [A] KOG0670 U4/U6-associated splicing factor PRP4 121 4e-27
Hs21389587 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 120 7e-27
SPCC777.14 [A] KOG0670 U4/U6-associated splicing factor PRP4 117 8e-26
Hs20468251 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 103 1e-21
Hs4503069 [T] KOG0660 Mitogen-activated protein kinase 99 2e-20
Hs20986516 [T] KOG0660 Mitogen-activated protein kinase 97 8e-20
Hs20986514 [T] KOG0660 Mitogen-activated protein kinase 97 8e-20
Hs20986512 [T] KOG0660 Mitogen-activated protein kinase 97 8e-20
Hs4507281 [R] KOG0593 Predicted protein kinase KKIAMRE 94 7e-19
SPAC24B11.06c [T] KOG0660 Mitogen-activated protein kinase 94 9e-19
CE20258 [R] KOG0593 Predicted protein kinase KKIAMRE 93 1e-18
7297009 [R] KOG0593 Predicted protein kinase KKIAMRE 93 2e-18
SPBC8D2.01 [G] KOG0658 Glycogen synthase kinase-3 92 4e-18
Hs20128774 [T] KOG0660 Mitogen-activated protein kinase 91 5e-18
SPBC530.14c [T] KOG1290 Serine/threonine protein kinase 91 6e-18
SPBC11B10.09 [R] KOG0594 Protein kinase PCTAIRE and related kinases 91 6e-18
7298087 [T] KOG0660 Mitogen-activated protein kinase 89 2e-17
CE04173 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 88 4e-17
SPCC16C4.11 [R] KOG0594 Protein kinase PCTAIRE and related kinases 87 7e-17
CE06686 [T] KOG0660 Mitogen-activated protein kinase 87 9e-17
7303073 [T] KOG1290 Serine/threonine protein kinase 87 9e-17
YLR113w [T] KOG0660 Mitogen-activated protein kinase 86 1e-16
Hs16936528 [R] KOG0594 Protein kinase PCTAIRE and related kinases 86 1e-16
YGR040w [T] KOG0660 Mitogen-activated protein kinase 86 2e-16
Hs4758652 [R] KOG0593 Predicted protein kinase KKIAMRE 85 4e-16
Hs20562757 [T] KOG0660 Mitogen-activated protein kinase 85 4e-16
CE27574 [T] KOG0665 Jun-N-terminal kinase (JNK) 84 6e-16
Hs4507221 [T] KOG1290 Serine/threonine protein kinase 84 7e-16
CE26621 [T] KOG0671 LAMMER dual specificity kinases 84 7e-16
CE00315 [R] KOG0594 Protein kinase PCTAIRE and related kinases 84 7e-16
Hs7705551 [T] KOG0661 MAPK related serine/threonine protein kinase 84 1e-15
Hs7662388 [T] KOG0661 MAPK related serine/threonine protein kinase 83 1e-15
Hs18552621 [R] KOG0597 Serine-threonine protein kinase FUSED 83 2e-15
At5g14640 [G] KOG0658 Glycogen synthase kinase-3 83 2e-15
7296535 [T] KOG1290 Serine/threonine protein kinase 83 2e-15
HsM4504163 [G] KOG0658 Glycogen synthase kinase-3 82 2e-15
Hs7657629 [T] KOG1290 Serine/threonine protein kinase 82 2e-15
Hs21361340 [G] KOG0658 Glycogen synthase kinase-3 82 2e-15
CE19353_3 [T] KOG0671 LAMMER dual specificity kinases 82 3e-15
CE02602_1 [T] KOG0660 Mitogen-activated protein kinase 82 3e-15
Hs11496279 [T] KOG0661 MAPK related serine/threonine protein kinase 82 4e-15
7302908 [R] KOG0594 Protein kinase PCTAIRE and related kinases 82 4e-15
Hs4506785 [T] KOG0660 Mitogen-activated protein kinase 81 6e-15
7301110 [T] KOG0660 Mitogen-activated protein kinase 81 6e-15
Hs7706059 [R] KOG0593 Predicted protein kinase KKIAMRE 80 8e-15
Hs20986531 [T] KOG0660 Mitogen-activated protein kinase 80 8e-15
Hs20986529 [T] KOG0660 Mitogen-activated protein kinase 80 8e-15
CE29318 [T] KOG0660 Mitogen-activated protein kinase 80 8e-15
At1g50230 [R] KOG0597 Serine-threonine protein kinase FUSED 80 8e-15
7300773 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 80 8e-15
7290342 [G] KOG0658 Glycogen synthase kinase-3 80 8e-15
Hs4826684_1 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 80 8e-15
Hs4759052 [T] KOG0603 Ribosomal protein S6 kinase 80 1e-14
Hs4502743 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 80 1e-14
Hs4557439 [R] KOG0594 Protein kinase PCTAIRE and related kinases 80 1e-14
CE27415 [T] KOG0671 LAMMER dual specificity kinases 80 1e-14
CE17305 [T] KOG0665 Jun-N-terminal kinase (JNK) 80 1e-14
CE05507 [T] KOG0603 Ribosomal protein S6 kinase 80 1e-14
At3g04530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 80 1e-14
At1g06390 [G] KOG0658 Glycogen synthase kinase-3 80 1e-14
HsM20070143 [T] KOG0665 Jun-N-terminal kinase (JNK) 79 2e-14
Hs4505569 [R] KOG0593 Predicted protein kinase KKIAMRE 79 2e-14
Hs21237739 [T] KOG0665 Jun-N-terminal kinase (JNK) 79 2e-14
Hs21237736 [T] KOG0665 Jun-N-terminal kinase (JNK) 79 2e-14
At5g22840 [T] KOG1290 Serine/threonine protein kinase 79 2e-14
At3g18040 [T] KOG0660 Mitogen-activated protein kinase 79 2e-14
At3g48750 [R] KOG0594 Protein kinase PCTAIRE and related kinases 79 2e-14
At3g05840 [G] KOG0658 Glycogen synthase kinase-3 79 2e-14
At2g42880 [T] KOG0660 Mitogen-activated protein kinase 79 2e-14
YMR216c [T] KOG1290 Serine/threonine protein kinase 79 3e-14
SPBPI064 [G] KOG0658 Glycogen synthase kinase-3 79 3e-14
Hs22051130 [G] KOG0658 Glycogen synthase kinase-3 79 3e-14
Hs15834624 [T] KOG1290 Serine/threonine protein kinase 79 3e-14
Hs11995474 [G] KOG0658 Glycogen synthase kinase-3 79 3e-14
At4g18710 [G] KOG0658 Glycogen synthase kinase-3 79 3e-14
At1g54610 [D] KOG0600 Cdc2-related protein kinase 79 3e-14
CE04172 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 78 4e-14
At2g30980 [G] KOG0658 Glycogen synthase kinase-3 78 4e-14
Hs21237745 [T] KOG0665 Jun-N-terminal kinase (JNK) 78 5e-14
Hs21237742 [T] KOG0665 Jun-N-terminal kinase (JNK) 78 5e-14
Hs20986521 [T] KOG0665 Jun-N-terminal kinase (JNK) 78 5e-14
Hs20986519 [T] KOG0665 Jun-N-terminal kinase (JNK) 78 5e-14
CE21401 [G] KOG0658 Glycogen synthase kinase-3 78 5e-14
At5g26751 [G] KOG0658 Glycogen synthase kinase-3 78 5e-14
CE12408 [T] KOG0661 MAPK related serine/threonine protein kinase 77 7e-14
YJL106w [T] KOG0661 MAPK related serine/threonine protein kinase 77 9e-14
At3g61160 [G] KOG0658 Glycogen synthase kinase-3 77 1e-13
At5g19010 [T] KOG0660 Mitogen-activated protein kinase 75 3e-13
At3g45640 [T] KOG0660 Mitogen-activated protein kinase 75 3e-13
At1g57870 [G] KOG0658 Glycogen synthase kinase-3 75 3e-13
SPAC1687.15 [G] KOG0658 Glycogen synthase kinase-3 75 3e-13
CE17062 [T] KOG0660 Mitogen-activated protein kinase 75 3e-13
At3g17850 [TR] KOG0606 Microtubule-associated serine/threonine k... 75 3e-13
At1g18150 [T] KOG0660 Mitogen-activated protein kinase 75 3e-13
At1g18040 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 75 3e-13
7293139 [T] KOG1290 Serine/threonine protein kinase 75 3e-13
At1g76540 [R] KOG0594 Protein kinase PCTAIRE and related kinases 75 4e-13
Hs4506081 [T] KOG0665 Jun-N-terminal kinase (JNK) 74 6e-13
Hs4502735 [R] KOG0594 Protein kinase PCTAIRE and related kinases 74 6e-13
Hs20986510 [T] KOG0665 Jun-N-terminal kinase (JNK) 74 6e-13
Hs17461944 [R] KOG0593 Predicted protein kinase KKIAMRE 74 6e-13
CE29298 [T] KOG0690 Serine/threonine protein kinase 74 6e-13
CE18646 [T] KOG0690 Serine/threonine protein kinase 74 6e-13
7298004 [G] KOG0658 Glycogen synthase kinase-3 74 6e-13
Hs14777335 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 74 8e-13
ECU08g0230 [R] KOG0594 Protein kinase PCTAIRE and related kinases 74 8e-13
CE18967 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD a... 74 8e-13
Hs6912584 [R] KOG0594 Protein kinase PCTAIRE and related kinases 74 1e-12
Hs20986506 [T] KOG0665 Jun-N-terminal kinase (JNK) 74 1e-12
CE29466 [T] KOG0665 Jun-N-terminal kinase (JNK) 74 1e-12
7297631 [T] KOG0665 Jun-N-terminal kinase (JNK) 74 1e-12
7296346 [R] KOG0663 Protein kinase PITSLRE and related kinases 74 1e-12
YOL045w [T] KOG1152 Signal transduction serine/threonine kinase ... 73 1e-12
YMR139w [G] KOG0658 Glycogen synthase kinase-3 73 1e-12
At1g53510 [T] KOG0660 Mitogen-activated protein kinase 73 1e-12
7297680 [R] KOG0594 Protein kinase PCTAIRE and related kinases 73 1e-12
YHR030c [T] KOG0660 Mitogen-activated protein kinase 73 2e-12
SPAC2F3.15 [D] KOG0600 Cdc2-related protein kinase 73 2e-12
At1g20930 [R] KOG0594 Protein kinase PCTAIRE and related kinases 73 2e-12
At1g09840 [G] KOG0658 Glycogen synthase kinase-3 73 2e-12
YOR231w [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K) 72 2e-12
SPAC23A1.06c [T] KOG0032 Ca2+/calmodulin-dependent protein kinas... 72 2e-12
Hs4502741 [R] KOG0594 Protein kinase PCTAIRE and related kinases 72 2e-12
Hs22057171 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 72 2e-12
CE29020 [T] KOG0660 Mitogen-activated protein kinase 72 2e-12
At3g14720 [T] KOG0660 Mitogen-activated protein kinase 72 2e-12
7303804 [R] KOG0663 Protein kinase PITSLRE and related kinases 72 2e-12
YBL016w [T] KOG0660 Mitogen-activated protein kinase 72 3e-12
SPAC31G5.09c [T] KOG0660 Mitogen-activated protein kinase 72 3e-12
Hs7657526 [T] KOG0603 Ribosomal protein S6 kinase 72 3e-12
Hs14110390 [D] KOG0600 Cdc2-related protein kinase 72 3e-12
Hs14110387 [D] KOG0600 Cdc2-related protein kinase 72 3e-12
CE08727 [G] KOG0658 Glycogen synthase kinase-3 72 3e-12
CE06762 [T] KOG0660 Mitogen-activated protein kinase 72 3e-12
At3g44850 [T] KOG1290 Serine/threonine protein kinase 72 3e-12
Hs4759050 [T] KOG0603 Ribosomal protein S6 kinase 72 4e-12
Hs4506095 [T] KOG0665 Jun-N-terminal kinase (JNK) 72 4e-12
Hs20986523 [T] KOG0665 Jun-N-terminal kinase (JNK) 72 4e-12
CE29073 [R] KOG0594 Protein kinase PCTAIRE and related kinases 72 4e-12
CE06779 [R] KOG0594 Protein kinase PCTAIRE and related kinases 72 4e-12
7296450 [D] KOG0575 Polo-like serine/threonine protein kinase 72 4e-12
YFR014c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 71 5e-12
At3g13530 [T] KOG0198 MEKK and related serine/threonine protein ... 71 5e-12
YOL128c [G] KOG0658 Glycogen synthase kinase-3 71 6e-12
Hs14196445 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 71 6e-12
At4g00720 [G] KOG0658 Glycogen synthase kinase-3 71 6e-12
At1g12580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 71 6e-12
ECU11g0960 [D] KOG0600 Cdc2-related protein kinase 70 8e-12
CE18009 [R] KOG0594 Protein kinase PCTAIRE and related kinases 70 8e-12
At1g73670 [T] KOG0660 Mitogen-activated protein kinase 70 8e-12
Hs5453860 [R] KOG0594 Protein kinase PCTAIRE and related kinases 70 1e-11
Hs15011928 [R] KOG0594 Protein kinase PCTAIRE and related kinases 70 1e-11
ECU11g1500 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 70 1e-11
Hs4502745 [K] KOG0666 Cyclin C-dependent kinase CDK8 70 1e-11
Hs20479818 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 70 1e-11
Hs20149547 [T] KOG0603 Ribosomal protein S6 kinase 70 1e-11
Hs4502557 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 69 2e-11
ECU08g1920 [R] KOG0594 Protein kinase PCTAIRE and related kinases 69 2e-11
CE20458 [T] KOG1290 Serine/threonine protein kinase 69 2e-11
CE20457 [T] KOG1290 Serine/threonine protein kinase 69 2e-11
CE02949 [T] KOG1290 Serine/threonine protein kinase 69 2e-11
At2g38490 [T] KOG0583 Serine/threonine protein kinase 69 2e-11
YNR031c [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and r... 69 2e-11
SPBC8D2.19 [T] KOG0661 MAPK related serine/threonine protein kinase 69 2e-11
Hs7706549 [D] KOG0600 Cdc2-related protein kinase 69 2e-11
Hs4557511 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 69 2e-11
Hs14670383 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 69 2e-11
CE18608 [R] KOG0594 Protein kinase PCTAIRE and related kinases 69 2e-11
At3g07980 [T] KOG0198 MEKK and related serine/threonine protein ... 69 2e-11
At1g48490 [TR] KOG0606 Microtubule-associated serine/threonine k... 69 2e-11
Hs22050308_2 [T] KOG0198 MEKK and related serine/threonine prote... 69 2e-11
Hs4503095 [TDK] KOG0668 Casein kinase II alpha subunit 69 3e-11
Hs20551615 [K] KOG0666 Cyclin C-dependent kinase CDK8 69 3e-11
Hs20502986 [T] KOG0660 Mitogen-activated protein kinase 69 3e-11
At2g01450 [T] KOG0660 Mitogen-activated protein kinase 69 3e-11
CE26793_1 [R] KOG0611 Predicted serine/threonine protein kinase 69 3e-11
YAL017w [T] KOG1152 Signal transduction serine/threonine kinase ... 68 4e-11
SPACUNK12.02c [T] KOG0032 Ca2+/calmodulin-dependent protein kina... 68 4e-11
Hs7662170 [R] KOG0611 Predicted serine/threonine protein kinase 68 4e-11
At1g73690 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 68 4e-11
SPBC119.08 [T] KOG0660 Mitogen-activated protein kinase 68 5e-11
SPAC3C7.06c [T] KOG0661 MAPK related serine/threonine protein ki... 68 5e-11
Hs4506735 [T] KOG0603 Ribosomal protein S6 kinase 68 5e-11
Hs16160923 [R] KOG0594 Protein kinase PCTAIRE and related kinases 68 5e-11
At1g54960 [T] KOG0198 MEKK and related serine/threonine protein ... 68 5e-11
7291043 [T] KOG0660 Mitogen-activated protein kinase 68 5e-11
YDL079c [G] KOG0658 Glycogen synthase kinase-3 67 7e-11
Hs9966875 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 67 7e-11
CE24516 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 67 7e-11
YOL016c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 67 1e-10
Hs7706445 [T] KOG0664 Nemo-like MAPK-related serine/threonine pr... 67 1e-10
At3g10540 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 67 1e-10
SPCC1322.08 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 66 2e-10
Hs20986508 [T] KOG0665 Jun-N-terminal kinase (JNK) 66 2e-10
CE20167 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD a... 66 2e-10
At3g53030 [T] KOG1290 Serine/threonine protein kinase 66 2e-10
7294866 [K] KOG0666 Cyclin C-dependent kinase CDK8 66 2e-10
SPAC23H4.17c [K] KOG0666 Cyclin C-dependent kinase CDK8 66 2e-10
Hs16418343 [T] KOG0583 Serine/threonine protein kinase 66 2e-10
CE28918 [R] KOG0594 Protein kinase PCTAIRE and related kinases 66 2e-10
Hs21361433 [D] KOG0575 Polo-like serine/threonine protein kinase 65 3e-10
Hs19923570 [T] KOG0603 Ribosomal protein S6 kinase 65 3e-10
CE27768 [R] KOG0586 Serine/threonine protein kinase 65 3e-10
CE23838 [R] KOG0586 Serine/threonine protein kinase 65 3e-10
CE15475 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 65 3e-10
CE15473 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 65 3e-10
At5g44290 [D] KOG0600 Cdc2-related protein kinase 65 3e-10
At1g53700 [R] KOG0610 Putative serine/threonine protein kinase 65 3e-10
7290565 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 65 3e-10
YPL203w [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 65 4e-10
SPCC18B5.11c [D] KOG0615 Serine/threonine protein kinase Chk2 an... 65 4e-10
SPBC32H8.10 [D] KOG0600 Cdc2-related protein kinase 65 4e-10
SPAC24B11.11c [R] KOG0605 NDR and related serine/threonine kinases 65 4e-10
HsM7657627 [D] KOG0575 Polo-like serine/threonine protein kinase 65 4e-10
Hs15619015 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 65 4e-10
At1g76040 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 65 4e-10
Hs21040235 [R] KOG0594 Protein kinase PCTAIRE and related kinases 65 5e-10
SPAC2C4.14c [T] KOG0201 Serine/threonine protein kinase 64 6e-10
Hs4507831 [OUT] KOG0595 Serine/threonine-protein kinase involved... 64 6e-10
ECU07g1270 [G] KOG0658 Glycogen synthase kinase-3 64 6e-10
CE18454 [T] KOG4717 Serine/threonine protein kinase 64 6e-10
CE03584 [T] KOG0607 MAP kinase-interacting kinase and related se... 64 6e-10
At3g15220 [T] KOG0201 Serine/threonine protein kinase 64 6e-10
At3g06030 [T] KOG0198 MEKK and related serine/threonine protein ... 64 6e-10
7291442 [D] KOG0669 Cyclin T-dependent kinase CDK9 64 6e-10
Hs4505649 [R] KOG0594 Protein kinase PCTAIRE and related kinases 64 8e-10
ECU08g1480 [R] KOG0586 Serine/threonine protein kinase 64 8e-10
CE25437 [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K) 64 8e-10
CE17815 [K] KOG0666 Cyclin C-dependent kinase CDK8 64 8e-10
At1g66750 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 64 8e-10
At1g45160 [TR] KOG0606 Microtubule-associated serine/threonine k... 64 8e-10
At1g03740 [D] KOG0600 Cdc2-related protein kinase 64 8e-10
7303211 [T] KOG4717 Serine/threonine protein kinase 64 8e-10
7293496 [R] KOG0597 Serine-threonine protein kinase FUSED 64 8e-10
Hs6005922_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 64 8e-10
Hs13569922 [R] KOG0611 Predicted serine/threonine protein kinase 64 1e-09
CE29612 [R] KOG0594 Protein kinase PCTAIRE and related kinases 64 1e-09
At5g04510 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 64 1e-09
Hs6005850 [D] KOG0615 Serine/threonine protein kinase Chk2 and r... 63 1e-09
CE19294 [T] KOG0198 MEKK and related serine/threonine protein ki... 63 1e-09
CE04603 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 63 1e-09
7296451 [D] KOG0600 Cdc2-related protein kinase 63 1e-09
YLR248w [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 63 2e-09
ECU03g0980 [T] KOG0583 Serine/threonine protein kinase 63 2e-09
CE27220 [T] KOG0660 Mitogen-activated protein kinase 63 2e-09
CE01554 [T] KOG0986 G protein-coupled receptor kinase 63 2e-09
Hs4758128_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 63 2e-09
Hs4758192 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 62 2e-09
Hs4506057 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 62 2e-09
Hs4506055 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 62 2e-09
CE18169 [T] KOG0603 Ribosomal protein S6 kinase 62 2e-09
CE13014 [T] KOG0603 Ribosomal protein S6 kinase 62 2e-09
At1g61950 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 62 2e-09
YGL158w [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 62 3e-09
Hs7706286 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase E... 62 3e-09
Hs5453882 [G] KOG0599 Phosphorylase kinase gamma subunit 62 3e-09
CE28061 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 62 3e-09
CE28060 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 62 3e-09
CE28059 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 62 3e-09
CE28058 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 62 3e-09
CE28057 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 62 3e-09
CE28056 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 62 3e-09
CE28055 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 62 3e-09
CE28054 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 62 3e-09
CE28053 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 62 3e-09
CE28051 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 62 3e-09
At4g11330 [T] KOG0660 Mitogen-activated protein kinase 62 3e-09
At4g04700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 62 3e-09
At3g17510 [T] KOG0583 Serine/threonine protein kinase 62 3e-09
7292375 [R] KOG0594 Protein kinase PCTAIRE and related kinases 62 3e-09
YCR073c [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and r... 62 4e-09
Hs5174547 [T] KOG4279 Serine/threonine protein kinase 62 4e-09
Hs4502553 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 62 4e-09
Hs16936530 [R] KOG0594 Protein kinase PCTAIRE and related kinases 62 4e-09
ECU07g0360 [D] KOG0580 Serine/threonine protein kinase 62 4e-09
At2g46700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 62 4e-09
YPL153c [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 61 5e-09
CE21213 [UT] KOG0662 Cyclin-dependent kinase CDK5 61 5e-09
CE01761 [R] KOG0663 Protein kinase PITSLRE and related kinases 61 5e-09
At5g25110 [T] KOG0583 Serine/threonine protein kinase 61 5e-09
At3g49370 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 61 5e-09
7295431 [D] KOG0601 Cyclin-dependent kinase WEE1 61 5e-09
YPR111w [R] KOG0605 NDR and related serine/threonine kinases 61 7e-09
YJL095w [T] KOG0198 MEKK and related serine/threonine protein ki... 61 7e-09
HsM4505191 [T] KOG0607 MAP kinase-interacting kinase and related... 61 7e-09
Hs9994197 [T] KOG0607 MAP kinase-interacting kinase and related ... 61 7e-09
7299507 [T] KOG0607 MAP kinase-interacting kinase and related se... 61 7e-09
7294537 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 61 7e-09
Hs19311016_1 [R] KOG0589 Serine/threonine protein kinase 61 7e-09
YNR047w [R] KOG0610 Putative serine/threonine protein kinase 60 9e-09
YKL101w [D] KOG0588 Serine/threonine protein kinase 60 9e-09
YGR092w [R] KOG0605 NDR and related serine/threonine kinases 60 9e-09
Hs7662210 [OUT] KOG0595 Serine/threonine-protein kinase involved... 60 1e-08
At5g24430 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 60 1e-08
YOR061w [TDK] KOG0668 Casein kinase II alpha subunit 60 1e-08
SPCC4G3.08 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 60 1e-08
CE21086 [D] KOG0590 Checkpoint kinase and related serine/threoni... 60 1e-08
At2g41910 [T] KOG0198 MEKK and related serine/threonine protein ... 60 1e-08
Hs4505695 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 59 2e-08
Hs4502747 [D] KOG0669 Cyclin T-dependent kinase CDK9 59 2e-08
Hs14149671 [TR] KOG0606 Microtubule-associated serine/threonine ... 59 2e-08
CE21879 [D] KOG0590 Checkpoint kinase and related serine/threoni... 59 2e-08
CE02377 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 59 2e-08
At5g45430 [T] KOG0661 MAPK related serine/threonine protein kinase 59 2e-08
At3g12690 [R] KOG0610 Putative serine/threonine protein kinase 59 2e-08
At2g41860 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 59 2e-08
At2g17290 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 59 2e-08
7300106 [T] KOG0690 Serine/threonine protein kinase 59 2e-08
CE28674 [T] KOG0201 Serine/threonine protein kinase 59 3e-08
CE07510 [T] KOG0201 Serine/threonine protein kinase 59 3e-08
At5g45820 [T] KOG0583 Serine/threonine protein kinase 59 3e-08
At3g57530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 59 3e-08
Hs14993776 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 59 3e-08
At5g57630 [T] KOG0583 Serine/threonine protein kinase 59 3e-08
At3g44200 [R] KOG0589 Serine/threonine protein kinase 59 3e-08
At3g20410 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 59 3e-08
At2g42550 [T] KOG0198 MEKK and related serine/threonine protein ... 59 3e-08
7304283 [Z] KOG0613 Projectin/twitchin and related proteins 59 3e-08
7294265 [TR] KOG0606 Microtubule-associated serine/threonine kin... 59 3e-08
YKL139w [D] KOG0600 Cdc2-related protein kinase 58 6e-08
SPCC63.08c [OUT] KOG0595 Serine/threonine-protein kinase involve... 58 6e-08
SPBC19F8.07 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polyme... 58 6e-08
Hs14776113 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 58 6e-08
CE17284 [T] KOG0583 Serine/threonine protein kinase 58 6e-08
CE15612 [T] KOG0690 Serine/threonine protein kinase 58 6e-08
CE04522 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 58 6e-08
At5g19360 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 58 6e-08
At1g30270 [T] KOG0583 Serine/threonine protein kinase 58 6e-08
At1g12680 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 58 6e-08
7292249 [T] KOG0587 Traf2- and Nck-interacting kinase and relate... 58 6e-08
Hs14728804 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 57 7e-08
CE25046 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 57 7e-08
At4g35310 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 57 7e-08
At1g74330 [D] KOG0600 Cdc2-related protein kinase 57 7e-08
7296128 [T] KOG0583 Serine/threonine protein kinase 57 7e-08
YDL159w [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K) 57 1e-07
Hs21389411 [T] KOG0694 Serine/threonine protein kinase 57 1e-07
CE05274 [T] KOG0690 Serine/threonine protein kinase 57 1e-07
At1g50700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 57 1e-07
Hs6031180 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and... 57 1e-07
Hs5803088 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and... 57 1e-07
Hs20543401 [TR] KOG0606 Microtubule-associated serine/threonine ... 57 1e-07
Hs14916455 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 57 1e-07
CE28643 [T] KOG0583 Serine/threonine protein kinase 57 1e-07
CE07458 [T] KOG0583 Serine/threonine protein kinase 57 1e-07
At3g51850 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 57 1e-07
At2g31500 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 57 1e-07
At2g17890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 57 1e-07
At1g18670 [D] KOG0600 Cdc2-related protein kinase 57 1e-07
YMR291w [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 56 2e-07
YDR490c [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 56 2e-07
YDL101c [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 56 2e-07
Hs4505785 [G] KOG0599 Phosphorylase kinase gamma subunit 56 2e-07
Hs14042966 [T] KOG0583 Serine/threonine protein kinase 56 2e-07
CE29478 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 56 2e-07
CE29477 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 56 2e-07
CE29476 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 56 2e-07
At5g12180 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 56 2e-07
At4g13000 [R] KOG0610 Putative serine/threonine protein kinase 56 2e-07
At3g19100 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 56 2e-07
7304311 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 56 2e-07
CE29622 [T] KOG1006 Mitogen-activated protein kinase (MAPK) kina... 56 2e-07
CE28650 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 56 2e-07
7304358 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 56 2e-07
YDR477w [T] KOG0583 Serine/threonine protein kinase 55 3e-07
Hs5453966 [T] KOG0583 Serine/threonine protein kinase 55 3e-07
Hs5453964 [T] KOG0583 Serine/threonine protein kinase 55 3e-07
CE07599 [T] KOG0576 Mitogen-activated protein kinase kinase kina... 55 3e-07
At2g41920 [T] KOG0198 MEKK and related serine/threonine protein ... 55 3e-07
7290150 [T] KOG0583 Serine/threonine protein kinase 55 3e-07
YOL100w [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 55 4e-07
At5g66880 [T] KOG0583 Serine/threonine protein kinase 55 4e-07
At1g18890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 55 4e-07
YOL113w [T] KOG0578 p21-activated serine/threonine protein kinase 55 5e-07
SPBC18H10.15 [R] KOG0663 Protein kinase PITSLRE and related kinases 55 5e-07
HsM4758928 [D] KOG0601 Cyclin-dependent kinase WEE1 55 5e-07
Hs21361083 [D] KOG0601 Cyclin-dependent kinase WEE1 55 5e-07
Hs20547806 [R] KOG0589 Serine/threonine protein kinase 55 5e-07
CE12478 [D] KOG0590 Checkpoint kinase and related serine/threoni... 55 5e-07
At4g04740 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 55 5e-07
At2g23070 [TDK] KOG0668 Casein kinase II alpha subunit 55 5e-07
YAR018c [D] KOG0591 NIMA (never in mitosis)-related G2-specific ... 54 6e-07
SPCC576.15c [T] KOG0592 3-phosphoinositide-dependent protein kin... 54 6e-07
CE20236 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 54 6e-07
At3g23000 [T] KOG0583 Serine/threonine protein kinase 54 6e-07
7299438 [R] KOG0586 Serine/threonine protein kinase 54 6e-07
SPCC74.03c [T] KOG0583 Serine/threonine protein kinase 54 8e-07
SPCC417.06c [R] KOG0605 NDR and related serine/threonine kinases 54 8e-07
Hs18596354 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 54 8e-07
Hs15011880 [T] KOG0201 Serine/threonine protein kinase 54 8e-07
Hs14141724 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase ... 54 8e-07
At4g38470 [T] KOG0192 Tyrosine kinase specific for activated (GT... 54 8e-07
At1g29230 [T] KOG0583 Serine/threonine protein kinase 54 8e-07
YOR351c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 54 1e-06
SPBC1D7.05c [T] KOG0198 MEKK and related serine/threonine protei... 54 1e-06
HsM5454174 [T] KOG0201 Serine/threonine protein kinase 54 1e-06
Hs21361358 [T] KOG0201 Serine/threonine protein kinase 54 1e-06
At5g63610 [K] KOG0666 Cyclin C-dependent kinase CDK8 54 1e-06
At2g05060 [T] KOG0198 MEKK and related serine/threonine protein ... 54 1e-06
At1g49580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 54 1e-06
7300559 [T] KOG4279 Serine/threonine protein kinase 54 1e-06
7295933 [T] KOG1163 Casein kinase (serine/threonine/tyrosine pro... 54 1e-06
CE03754 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 53 1e-06
At3g14370 [R] KOG0610 Putative serine/threonine protein kinase 53 1e-06
At3g01090 [T] KOG0583 Serine/threonine protein kinase 53 1e-06
YLR362w [T] KOG0198 MEKK and related serine/threonine protein ki... 53 2e-06
SPBC4C3.11 [T] KOG0592 3-phosphoinositide-dependent protein kina... 53 2e-06
Hs4758700 [T] KOG0604 MAP kinase-activated protein kinase 2 53 2e-06
Hs17466653 [T] KOG1290 Serine/threonine protein kinase 53 2e-06
YKL161c [T] KOG0660 Mitogen-activated protein kinase 52 2e-06
Hs17455844 [TR] KOG0606 Microtubule-associated serine/threonine ... 52 2e-06
ECU11g1290 [R] KOG0663 Protein kinase PITSLRE and related kinases 52 2e-06
CE17354 [T] KOG0694 Serine/threonine protein kinase 52 2e-06
CE17353 [T] KOG0694 Serine/threonine protein kinase 52 2e-06
CE09430 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 52 2e-06
7299793 [T] KOG0583 Serine/threonine protein kinase 52 2e-06
SPAC9G1.02 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 an... 52 3e-06
SPAC23C4.12 [T] KOG1164 Casein kinase (serine/threonine/tyrosine... 52 3e-06
SPAC23C11.16 [D] KOG0575 Polo-like serine/threonine protein kinase 52 3e-06
CE26988 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 52 3e-06
At3g50530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 52 3e-06
At3g29160 [T] KOG0583 Serine/threonine protein kinase 52 3e-06
CE18539 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 52 4e-06
CE09360 [Z] KOG0613 Projectin/twitchin and related proteins 52 4e-06
At4g36070 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 52 4e-06
At2g17700 [T] KOG0192 Tyrosine kinase specific for activated (GT... 52 4e-06
SPBC337.04 [R] KOG0586 Serine/threonine protein kinase 51 5e-06
CE01519 [T] KOG1027 Serine/threonine protein kinase and endoribo... 51 5e-06
SPBC1861.09 [R] KOG0610 Putative serine/threonine protein kinase 51 7e-06
Hs16950621 [Z] KOG0613 Projectin/twitchin and related proteins 51 7e-06
Hs16950613 [Z] KOG0613 Projectin/twitchin and related proteins 51 7e-06
Hs16950611 [Z] KOG0613 Projectin/twitchin and related proteins 51 7e-06
Hs16950601 [Z] KOG0613 Projectin/twitchin and related proteins 51 7e-06
At2g34650 [R] KOG0610 Putative serine/threonine protein kinase 51 7e-06
7302202 [D] KOG1166 Mitotic checkpoint serine/threonine protein ... 51 7e-06
7300224 [T] KOG0201 Serine/threonine protein kinase 51 7e-06
At4g09570 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 50 9e-06
At1g35670 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 50 9e-06
Hs4502567_1 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase... 50 9e-06
>YLL019c [T] KOG0671 LAMMER dual specificity kinases
Length = 737
Score = 680 bits (1754), Expect = 0.0
Identities = 341/581 (58%), Positives = 424/581 (72%), Gaps = 39/581 (6%)
Query: 139 NSVNYTSAKKVKKQRTVSLPQLPHARLLYE------PRNTD----RRTQNDDELLHVSGT 188
NS T+ KK KKQRT+SLPQLP ++L Y+ P T+ R TQ ++ELLH++G+
Sbjct: 168 NSTYITTPKKFKKQRTISLPQLPLSKLSYQSNYFNVPDQTNAIVPRVTQTENELLHLTGS 227
Query: 189 TTQTVDGNKLIKLPLIRSLSPVPVADFRLXXXXXXXXXXXXXXFDISNSASKSPSRFTKI 248
+T++GNK + L + S SP ++ S S +
Sbjct: 228 CAKTLEGNKAVNLTIAHSTSPFSNPPAQIA----------------SLPQSNLKKQIGSS 271
Query: 249 LKKSPLLGSHQDKLRSMDRFKTDEEGHYVYQENDIFAKN-RFQAMQLLGQGTFGKVVKCK 307
L+K GS + + FKTD++GHYVYQENDIF RF LLGQGTFGKV+KC
Sbjct: 272 LRKFTSNGSSESASSNKSNFKTDKDGHYVYQENDIFGSGGRFVVKDLLGQGTFGKVLKCI 331
Query: 308 DYLNDIT-VAVKIIRAVDRYRQAAKTELRVLQTIKENDRSGQYQCLLLREFFDYKNHICL 366
D + VAVK+IRAVDRYR+AAKTELR+LQTI ND GQ+QCLLLRE FDYKNHICL
Sbjct: 332 DNKYEPNYVAVKVIRAVDRYREAAKTELRILQTILNNDPQGQFQCLLLRECFDYKNHICL 391
Query: 367 VTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQLVRSVCFLHDLGIIHTDLKPENILICDE 426
VTDLYGRS+YDFM +NG ARFPGSH+QAI +QL+RSVCFLHDLGIIHTDLKPENILICDE
Sbjct: 392 VTDLYGRSIYDFMCSNGIARFPGSHIQAIARQLIRSVCFLHDLGIIHTDLKPENILICDE 451
Query: 427 TCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKLIDFGSAVFYNEYHPPVVSTRHYR 486
T + Q LP++ + SL++RR+ AS GKRKIL NPE+K+IDFGSA+F+ EYHPPV+STRHYR
Sbjct: 452 THIAQKLPLKTVQSLSKRRREASKGKRKILKNPEIKIIDFGSAIFHYEYHPPVISTRHYR 511
Query: 487 APEIVLGLGWSFPCDIWSIACVLVELVTGESLYPIHENTEHMAMMQRINNEKFPKKMVEK 546
APEIVLGLGWSFPCDIWSIACVLVELV GESLYPIHEN EHMAMMQRIN FP +++K
Sbjct: 512 APEIVLGLGWSFPCDIWSIACVLVELVIGESLYPIHENLEHMAMMQRINGTPFPTDIIDK 571
Query: 547 MFFKVENKYGSIPTDLQTSVVKYFDRQTGELRWPLRNSKGQVITKEKSWKRILATCDRLD 606
MF+K ++K G+ P+DL ++V+K+FDR+T L+WP +N +G IT EKS KR+L +CDRLD
Sbjct: 572 MFYKSKHKLGNSPSDLNSTVIKHFDRKTLSLQWPEKNKRGDTITTEKSMKRVLQSCDRLD 631
Query: 607 VFISKKLQMDYGSWLEIHWDMQLEDNWRLILSK-----------NIDSRNIDKNVFMFWY 655
++ISK L+ DYG L I+W++ E NW LI SK + + +DK F+FWY
Sbjct: 632 IYISKVLKQDYGDSLSINWNLPPEKNWSLINSKLAWKRQTHSSSSSTTDELDKETFLFWY 691
Query: 656 YFVDLCRKMFEFDPTKRITAKEVIEHEWFNIGILDEGISHY 696
+F+DL RKMFEFDPTKRITAK+ ++HEWFN+GILD+GI+ Y
Sbjct: 692 WFIDLLRKMFEFDPTKRITAKDALDHEWFNLGILDDGIATY 732
>SPAC1D4.11c [T] KOG0671 LAMMER dual specificity kinases
Length = 690
Score = 299 bits (766), Expect = 9e-81
Identities = 160/414 (38%), Positives = 237/414 (56%), Gaps = 76/414 (18%)
Query: 271 DEEGHYVYQENDIFAKNRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAA 330
D++GHY N FA NR+ ++LLG GTFGKV++C D A+K+ RA+ +YR+A+
Sbjct: 345 DDDGHYKVVPNSKFA-NRYTVVRLLGHGTFGKVIQCYDQSTGRHCAIKVTRAIPKYREAS 403
Query: 331 KTELRVLQTIKENDRSGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGS 390
ELRVLQTI +D + + +C+ LR++FDY+ HIC+VTDL+G SV+DF+ NN Y FP
Sbjct: 404 LIELRVLQTIAHSDPTNENKCIQLRDYFDYRKHICIVTDLFGWSVFDFLKNNNYIPFPLK 463
Query: 391 HVQAIGKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASG 450
H+Q + +QL +SV FLH LG++HTDLKPEN+L+ LP
Sbjct: 464 HIQMLSQQLFKSVAFLHSLGLVHTDLKPENVLLVSNASRTIRLPYR-------------N 510
Query: 451 GKRKILINPEVKLIDFGSAVFYNEYHPPVVSTRHYRAPEIVLGLGWSFPCDIWSIACVLV 510
+K+L + E++LIDFGSA F +EYH VVSTRHYRAPEI+LGLGWS+PCD+WSI C+LV
Sbjct: 511 YSQKVLNSCEIRLIDFGSATFEDEYHSSVVSTRHYRAPEIILGLGWSYPCDVWSIGCILV 570
Query: 511 ELVTGESLYPIHENTEHMAMMQRINNEKFPKKMVEKMFFKVENKYGSIPTDLQTSVVKYF 570
EL TG++L+ HE++EH+ MM++I F + M+ + + + F
Sbjct: 571 ELFTGQALFQTHEDSEHLCMMEKILG-PFDRNMISR----------------SSRTSQRF 613
Query: 571 DRQTGELRWPLRNSKGQVITKEKSWKRILATCDRLDVFISKKLQMDYGSWLEIHWDMQLE 630
+ G++R+PL N+ K ++ + L T +++ S ++ +
Sbjct: 614 FKSDGKVRYPLSNTP----KKSINYLQSLQTLEQIFAVSSPEVAL--------------- 654
Query: 631 DNWRLILSKNIDSRNIDKNVFMFWYYFVDLCRKMFEFDPTKRITAKEVIEHEWF 684
+DL +K+F +DP +RITAKE + H +F
Sbjct: 655 --------------------------LLDLLKKVFVYDPKRRITAKEALWHPFF 682
>At3g53570 [T] KOG0671 LAMMER dual specificity kinases
Length = 467
Score = 260 bits (664), Expect = 6e-69
Identities = 151/415 (36%), Positives = 227/415 (54%), Gaps = 70/415 (16%)
Query: 271 DEEGHYVYQENDIFAKNRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAA 330
D++GHYV+ D R+Q + +G+GTFG+V++C D N VA+K+IR++++YR+AA
Sbjct: 98 DKDGHYVFVVGDTLTP-RYQILSKMGEGTFGQVLECFDNKNKEVVAIKVIRSINKYREAA 156
Query: 331 KTELRVLQTIKENDRSGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGS 390
E+ VLQ + +D G +C+ +R +FDY+NHIC+V + G S+YDF+ N Y FP
Sbjct: 157 MIEIDVLQRLTRHDVGGS-RCVQIRNWFDYRNHICIVFEKLGPSLYDFLRKNSYRSFPID 215
Query: 391 HVQAIGKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASG 450
V+ +G+QL+ SV ++HDL +IHTDLKPENIL+ ++ I D R G
Sbjct: 216 LVRELGRQLLESVAYMHDLRLIHTDLKPENILLVSSEYIK------IPDYKFLSRPTKDG 269
Query: 451 GKRKILINPE-VKLIDFGSAVFYNEYHPPVVSTRHYRAPEIVLGLGWSFPCDIWSIACVL 509
K L +KLIDFGS F ++ H +VSTRHYRAPE++LG+GW++PCD+WSI C+L
Sbjct: 270 SYFKNLPKSSAIKLIDFGSTTFEHQDHNYIVSTRHYRAPEVILGVGWNYPCDLWSIGCIL 329
Query: 510 VELVTGESLYPIHENTEHMAMMQRINNEKFPKKMVEKMFFKVENKYGSIPTDLQTSVVKY 569
VEL +GE+L+ HEN EH+AMM+R+ P MV + + E KY
Sbjct: 330 VELCSGEALFQTHENLEHLAMMERVLG-PLPPHMVLRADRRSE---------------KY 373
Query: 570 FDRQTGELRWPLRNSKGQVITKEKSWKRILATCDRLDVFISKKLQMDYGSWLEIHWDMQL 629
F R+ +L WP + T S K +
Sbjct: 374 F-RRGAKLDWP------EGATSRDSLKAV------------------------------- 395
Query: 630 EDNWRLILSKNIDSRNIDKNVFMFWYYFVDLCRKMFEFDPTKRITAKEVIEHEWF 684
W+L N+ +++D + +DL + + +DPT+R A+E + H +F
Sbjct: 396 ---WKLPRLPNLIMQHVDHSA----GDLIDLLQGLLRYDPTERFKAREALNHPFF 443
>Hs4758008 [T] KOG0671 LAMMER dual specificity kinases
Length = 484
Score = 257 bits (657), Expect = 4e-68
Identities = 147/417 (35%), Positives = 224/417 (53%), Gaps = 82/417 (19%)
Query: 271 DEEGHYVYQENDIFAKNRFQAMQLLGQGTFGKVVKCKDY-LNDITVAVKIIRAVDRYRQA 329
DEEGH + Q D+ + R++ + LG+G FGKVV+C D+ VAVKI++ VDRY +A
Sbjct: 144 DEEGHLICQSGDVLSA-RYEIVDTLGEGAFGKVVECIDHKAGGRHVAVKIVKNVDRYCEA 202
Query: 330 AKTELRVLQTIKENDRSGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPG 389
A++E++VL+ + D + ++C+ + E+F++ HIC+V +L G S YDF+ NG+ F
Sbjct: 203 ARSEIQVLEHLNTTDPNSTFRCVQMLEWFEHHGHICIVFELLGLSTYDFIKENGFLPFRL 262
Query: 390 SHVQAIGKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLAS 449
H++ + Q+ +SV FLH + HTDLKPENIL E P D T
Sbjct: 263 DHIRKMAYQICKSVNFLHSNKLTHTDLKPENILFVQSDYTEAYNPKIKRDERT------- 315
Query: 450 GGKRKILINPEVKLIDFGSAVFYNEYHPPVVSTRHYRAPEIVLGLGWSFPCDIWSIACVL 509
LINP++K++DFGSA + +E+H +VSTRHYRAPE++L LGWS PCD+WSI C+L
Sbjct: 316 ------LINPDIKVVDFGSATYDDEHHSTLVSTRHYRAPEVILALGWSQPCDVWSIGCIL 369
Query: 510 VELVTGESLYPIHENTEHMAMMQRINNEKFPKKMVEKMFFKVENKYGSIPTDLQTSVVKY 569
+E G +++P H++ EH+AMM+RI PK M++K T KY
Sbjct: 370 IEYYLGFTVFPTHDSKEHLAMMERILG-PLPKHMIQK-----------------TRKRKY 411
Query: 570 FDRQTGELRWPLRNSKGQVITKEKSWKRILATCDRLDVFISKKLQMDYGSWLEIHWDMQL 629
F L W +S G+ +++ C L F
Sbjct: 412 FHHD--RLDWDEHSSAGRYVSR---------ACKPLKEF--------------------- 439
Query: 630 EDNWRLILSKNIDSRNIDKNVFMFWYYFVDLCRKMFEFDPTKRITAKEVIEHEWFNI 686
+LS++++ + DL +KM E+DP KRIT +E ++H +F++
Sbjct: 440 ------MLSQDVEHERL-----------FDLIQKMLEYDPAKRITLREALKHPFFDL 479
>Hs22045050 [T] KOG0671 LAMMER dual specificity kinases
Length = 484
Score = 257 bits (657), Expect = 4e-68
Identities = 147/417 (35%), Positives = 224/417 (53%), Gaps = 82/417 (19%)
Query: 271 DEEGHYVYQENDIFAKNRFQAMQLLGQGTFGKVVKCKDY-LNDITVAVKIIRAVDRYRQA 329
DEEGH + Q D+ + R++ + LG+G FGKVV+C D+ VAVKI++ VDRY +A
Sbjct: 144 DEEGHLICQSGDVLSA-RYEIVDTLGEGAFGKVVECIDHKAGGRHVAVKIVKNVDRYCEA 202
Query: 330 AKTELRVLQTIKENDRSGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPG 389
A++E++VL+ + D + ++C+ + E+F++ HIC+V +L G S YDF+ NG+ F
Sbjct: 203 ARSEIQVLEHLNTTDPNSTFRCVQMLEWFEHHGHICIVFELLGLSTYDFIKENGFLPFRL 262
Query: 390 SHVQAIGKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLAS 449
H++ + Q+ +SV FLH + HTDLKPENIL E P D T
Sbjct: 263 DHIRKMAYQICKSVNFLHSNKLTHTDLKPENILFVQSDYTEAYNPKIKRDERT------- 315
Query: 450 GGKRKILINPEVKLIDFGSAVFYNEYHPPVVSTRHYRAPEIVLGLGWSFPCDIWSIACVL 509
LINP++K++DFGSA + +E+H +VSTRHYRAPE++L LGWS PCD+WSI C+L
Sbjct: 316 ------LINPDIKVVDFGSATYDDEHHSTLVSTRHYRAPEVILALGWSQPCDVWSIGCIL 369
Query: 510 VELVTGESLYPIHENTEHMAMMQRINNEKFPKKMVEKMFFKVENKYGSIPTDLQTSVVKY 569
+E G +++P H++ EH+AMM+RI PK M++K T KY
Sbjct: 370 IEYYLGFTVFPTHDSKEHLAMMERILG-PLPKHMIQK-----------------TRKRKY 411
Query: 570 FDRQTGELRWPLRNSKGQVITKEKSWKRILATCDRLDVFISKKLQMDYGSWLEIHWDMQL 629
F L W +S G+ +++ C L F
Sbjct: 412 FHHD--RLDWDEHSSAGRYVSRR---------CKPLKEF--------------------- 439
Query: 630 EDNWRLILSKNIDSRNIDKNVFMFWYYFVDLCRKMFEFDPTKRITAKEVIEHEWFNI 686
+LS++++ + DL +KM E+DP KRIT +E ++H +F++
Sbjct: 440 ------MLSQDVEHERL-----------FDLIQKMLEYDPAKRITLREALKHPFFDL 479
>At4g24740 [T] KOG0671 LAMMER dual specificity kinases
Length = 427
Score = 253 bits (646), Expect = 7e-67
Identities = 146/414 (35%), Positives = 226/414 (54%), Gaps = 71/414 (17%)
Query: 271 DEEGHYVYQENDIFAKNRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAA 330
D++GHY+++ D R++ +G+GTFG+V++C D VAVKI+R V +YR+AA
Sbjct: 81 DKDGHYIFELGDDLTP-RYKIYSKMGEGTFGQVLECWDRERKEMVAVKIVRGVKKYREAA 139
Query: 331 KTELRVLQTIKENDRSGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGS 390
E+ +LQ + ++D+ G +C+ +R +FDY+NHIC+V + G S+YDF+ N Y FP
Sbjct: 140 MIEIEMLQQLGKHDKGGN-RCVQIRNWFDYRNHICIVFEKLGSSLYDFLRKNNYRSFPID 198
Query: 391 HVQAIGKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASG 450
V+ IG QL+ V F+HDL +IHTDLKPENIL+ V+ I R
Sbjct: 199 LVREIGWQLLECVAFMHDLRMIHTDLKPENILLVSSDYVK-------IPEYKGSRLQRDV 251
Query: 451 GKRKILINPEVKLIDFGSAVFYNEYHPPVVSTRHYRAPEIVLGLGWSFPCDIWSIACVLV 510
+++ + +K+IDFGS + + +VSTRHYRAPE++LGLGWS+PCD+WS+ C++V
Sbjct: 252 CYKRVPKSSAIKVIDFGSTTYERQDQTYIVSTRHYRAPEVILGLGWSYPCDVWSVGCIIV 311
Query: 511 ELVTGESLYPIHENTEHMAMMQRINNEKFPKKMVEKMFFKVENKYGSIPTDLQTSVVKYF 570
EL TGE+L+ HEN EH+AMM+R+ FP++M++K+ E KY
Sbjct: 312 ELCTGEALFQTHENLEHLAMMERVLG-PFPQQMLKKVDRHSE---------------KYV 355
Query: 571 DRQTGELRWPLRNSKGQVITKEKSWKRILATCDRLDVFISKKLQMDYGSWLEIHWDMQLE 630
R G L WP T S K +L
Sbjct: 356 RR--GRLDWP------DGATSRDSLKAVL------------------------------- 376
Query: 631 DNWRLILSKNIDSRNIDKNVFMFWYYFVDLCRKMFEFDPTKRITAKEVIEHEWF 684
+L +N+ +++D + +++ + + FDP++RITA+E + H +F
Sbjct: 377 ---KLPRLQNLIMQHVDHSA----GELINMVQGLLRFDPSERITAREALRHPFF 423
>CE05549 [T] KOG0671 LAMMER dual specificity kinases
Length = 903
Score = 246 bits (628), Expect = 9e-65
Identities = 132/315 (41%), Positives = 193/315 (60%), Gaps = 8/315 (2%)
Query: 233 DISNSASKSPSRFTKILKKSPLLGSHQDKLRSMDRFKTDEEGHYVYQENDIFAKNRFQAM 292
D + S+S + ++ K P + S Q + + D++GH +Y + D F NRF
Sbjct: 501 DKARKPSRSGLQASQARPKVPEIVSSQ-----RTQHQDDKDGHLIYSKGD-FILNRFTIY 554
Query: 293 QLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKENDRSGQYQCL 352
LG+GTFGKVV+ D L+D +A+KII+ V +YR+AAK E++VLQ + E D + +
Sbjct: 555 DTLGEGTFGKVVRVNDSLSDTFMALKIIKNVSKYREAAKLEVKVLQKLAEKDPEKKNWVI 614
Query: 353 LLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQLVRSVCFLHDLGII 412
+ +FDY HICL+ DL G S++DF+ N Y +P I QL +V FLHD +
Sbjct: 615 HMGSYFDYNGHICLLFDLMGSSIFDFLKANHYKPYPMEQTLHITWQLCNAVKFLHDNKLT 674
Query: 413 HTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGK-RKILINPEVKLIDFGSAVF 471
HTDLKPENIL D + + ++ + R K+ + ++L + V+LIDFGSA F
Sbjct: 675 HTDLKPENILFVDSRYTTKLVDKKVGKFVLRRFKIDDCFQPLRVLHSTHVRLIDFGSATF 734
Query: 472 YNEYHPPVVSTRHYRAPEIVLGLGWSFPCDIWSIACVLVELVTGESLYPIHENTEHMAMM 531
+E+H +VSTRHYRAPE++L LGWS PCD+WSI C+L EL TG +L+ HEN EH+AMM
Sbjct: 735 DHEHHSIIVSTRHYRAPEVILELGWSQPCDVWSIGCILYELYTGVTLFQTHENREHLAMM 794
Query: 532 QRINNEKFPKKMVEK 546
+R+ + P +M ++
Sbjct: 795 ERVLGD-IPLRMAKR 808
>At4g32660 [T] KOG0671 LAMMER dual specificity kinases
Length = 400
Score = 244 bits (624), Expect = 2e-64
Identities = 150/417 (35%), Positives = 226/417 (53%), Gaps = 77/417 (18%)
Query: 271 DEEGHYVYQENDIFAKNRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAA 330
D +GHYV+ D R++ + +G+GTFG+V++C D VA+KIIR++ +YR AA
Sbjct: 54 DRDGHYVFSLRDNLTP-RYKILSKMGEGTFGRVLECWDRDTKEYVAIKIIRSIKKYRDAA 112
Query: 331 KTELRVLQTIKENDRSGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGS 390
E+ VLQ + ++D+ G+ +C+ ++ +FDY+NHIC+V + G S++DF+ N Y+ FP +
Sbjct: 113 MIEIDVLQKLVKSDK-GRTRCVQMKNWFDYRNHICIVFEKLGPSLFDFLKRNKYSAFPLA 171
Query: 391 HVQAIGKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASG 450
V+ G QL+ SV ++H+L ++HTDLKPENIL+ V+ L + ++ A+
Sbjct: 172 LVRDFGCQLLESVAYMHELQLVHTDLKPENILLVSSENVK----------LPDNKRSAAN 221
Query: 451 GK--RKILINPEVKLIDFGSAVFYNEYHPPVVSTRHYRAPEIVLGLGWSFPCDIWSIACV 508
R + + +KLIDFGS V N H +V TRHYR+PE++LGLGWS+ CD+WSI C+
Sbjct: 222 ETHFRCLPKSSAIKLIDFGSTVCDNRIHHSIVQTRHYRSPEVILGLGWSYQCDLWSIGCI 281
Query: 509 LVELVTGESLYPIHENTEHMAMMQRINNEKFPKKMVEKMFFKVENKYGSIPTDLQTSVVK 568
L EL TGE+L+ H+N EH+AMM+R P+ M K E K
Sbjct: 282 LFELCTGEALFQTHDNLEHLAMMERALG-PLPEHMTRKASRGAE---------------K 325
Query: 569 YFDRQTGELRWPL-RNSKGQVITKEKSWKRILATCDRLDVFISKKLQMDYGSWLEIHWDM 627
YF R+ L WP NS+ + R + DRL +SK +
Sbjct: 326 YF-RRGCRLNWPEGANSRESI--------RAVKRLDRLKDMVSKHV-------------- 362
Query: 628 QLEDNWRLILSKNIDSRNIDKNVFMFWYYFVDLCRKMFEFDPTKRITAKEVIEHEWF 684
DN R SR F DL + +DP++R+TA E ++H +F
Sbjct: 363 ---DNTR--------SR------------FADLLYGLLAYDPSERLTANEALDHPFF 396
>7301719 [T] KOG0671 LAMMER dual specificity kinases
Length = 517
Score = 242 bits (617), Expect = 2e-63
Identities = 147/415 (35%), Positives = 214/415 (51%), Gaps = 82/415 (19%)
Query: 271 DEEGHYVYQENDIFAKNRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAA 330
D +GH +Y DI +R++ M LG+GTFG+VVK KD D +A+KII+ V++YR+AA
Sbjct: 153 DADGHLIYHTGDIL-HHRYKIMATLGEGTFGRVVKVKDMERDYCMALKIIKNVEKYREAA 211
Query: 331 KTELRVLQTIKENDRSGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGS 390
K E+ L+ I + D + C+ + ++FDY H+C+V ++ G SV+DF+ N Y +P
Sbjct: 212 KLEINALEKIAQKDPHCDHLCVKMIDWFDYHGHMCIVFEMLGLSVFDFLRENNYEPYPLD 271
Query: 391 HVQAIGKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASG 450
V+ + QL SV FLHD + HTDLKPENIL D D + +
Sbjct: 272 QVRHMAYQLCYSVKFLHDNRLTHTDLKPENILFVDS------------DYTSHYNHKINR 319
Query: 451 GKRKILINPEVKLIDFGSAVFYNEYHPPVVSTRHYRAPEIVLGLGWSFPCDIWSIACVLV 510
R++ N +V+LIDFGSA F +E+H +VSTRHYRAPE++L LGWS PCD+WSI C+L
Sbjct: 320 EVRRVK-NTDVRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSQPCDVWSIGCILF 378
Query: 511 ELVTGESLYPIHENTEHMAMMQRINNEKFPKKMVEKMFFKVENKYGSIPTDLQTSVVKYF 570
EL G +L+ H+N EH+AMM+RI + P +M K + KYF
Sbjct: 379 ELYLGITLFQTHDNREHLAMMERILGQ-IPYRMARK------------------TKTKYF 419
Query: 571 DRQTGELRWPLRNSKGQVITKEKSWKRILATCDRLDVFISKKLQMDYGSWLEIHWDMQLE 630
G+L W ++S G+ + + + L C D E
Sbjct: 420 --YHGKLDWDEKSSAGRYV---RDHCKPLFLCQLSD----------------------SE 452
Query: 631 DNWRLILSKNIDSRNIDKNVFMFWYYFVDLCRKMFEFDPTKRITAKEVIEHEWFN 685
D+ L L +KM E++P+ RIT E + H +F+
Sbjct: 453 DHCELF----------------------SLIKKMLEYEPSSRITLGEALHHPFFD 485
>Hs10190706 [T] KOG0671 LAMMER dual specificity kinases
Length = 481
Score = 239 bits (611), Expect = 8e-63
Identities = 128/348 (36%), Positives = 209/348 (59%), Gaps = 26/348 (7%)
Query: 237 SASKSPSRFTKILKKSPLLGSHQDKLRSMDRFKT-----DEEGHYVYQENDIFAKNRFQA 291
S SP R K++ SHQ + +S R ++ DEEGH + Q D+ + R++
Sbjct: 108 SRRSSPKR-----KRNRHCSSHQSRSKSHRRKRSRSIEDDEEGHLICQSGDVL-RARYEI 161
Query: 292 MQLLGQGTFGKVVKCKDY-LNDITVAVKIIRAVDRYRQAAKTELRVLQTIKENDRSGQYQ 350
+ LG+G FGKVV+C D+ ++ + VAVKI++ V RYR+AA++E++VL+ + D + ++
Sbjct: 162 VDTLGEGAFGKVVECIDHGMDGMHVAVKIVKNVGRYREAARSEIQVLEHLNSTDPNSVFR 221
Query: 351 CLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQLVRSVCFLHDLG 410
C+ + E+FD+ H+C+V +L G S YDF+ N + F H++ + Q+ +S+ FLH
Sbjct: 222 CVQMLEWFDHHGHVCIVFELLGLSTYDFIKENSFLPFQIDHIRQMAYQICQSINFLHHNK 281
Query: 411 IIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKLIDFGSAV 470
+ HTDLKPENIL V + +S +R + + L N ++K++DFGSA
Sbjct: 282 LTHTDLKPENILFVKSDYVVK------YNSKMKRDE-------RTLKNTDIKVVDFGSAT 328
Query: 471 FYNEYHPPVVSTRHYRAPEIVLGLGWSFPCDIWSIACVLVELVTGESLYPIHENTEHMAM 530
+ +E+H +VSTRHYRAPE++L LGWS PCD+WSI C+L+E G +++ H++ EH+AM
Sbjct: 329 YDDEHHSTLVSTRHYRAPEVILALGWSQPCDVWSIGCILIEYYLGFTVFQTHDSKEHLAM 388
Query: 531 MQRINNEKFPKKMVEKMFFKVENKYGSIPTDLQTSVVKYFDRQTGELR 578
M+RI P+ M++K + + + D +S +Y R+ L+
Sbjct: 389 MERILG-PIPQHMIQKTRKRKYFHHNQLDWDEHSSAGRYVRRRCKPLK 435
>Hs4502883_2 [T] KOG0671 LAMMER dual specificity kinases
Length = 363
Score = 232 bits (591), Expect = 2e-60
Identities = 140/416 (33%), Positives = 216/416 (51%), Gaps = 84/416 (20%)
Query: 271 DEEGHYVYQENDIFAKNRFQAMQLLGQGTFGKVVKCKDYLND-ITVAVKIIRAVDRYRQA 329
D EGH +Y D + + R++ + LG+GTFG+VV+C D+ VA+KII+ V++Y++A
Sbjct: 10 DAEGHLIYHVGD-WLQERYEIVSTLGEGTFGRVVQCVDHRRGGARVALKIIKNVEKYKEA 68
Query: 330 AKTELRVLQTIKENDRSGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPG 389
A+ E+ VL+ I E D + C+ + ++FDY H+C+ +L G S +DF+ +N Y +P
Sbjct: 69 ARLEINVLEKINEKDPDNKNLCVQMFDWFDYHGHMCISFELLGLSTFDFLKDNNYLPYPI 128
Query: 390 SHVQAIGKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLAS 449
V+ + QL ++V FLHD + HTDLKPENIL + E+ +L ++R S
Sbjct: 129 HQVRHMAFQLCQAVKFLHDNKLTHTDLKPENILFVNSD-------YELTYNLEKKRDERS 181
Query: 450 GGKRKILINPEVKLIDFGSAVFYNEYHPPVVSTRHYRAPEIVLGLGWSFPCDIWSIACVL 509
+ + V+++DFGSA F +E+H +VSTRHYRAPE++L LGWS PCD+WSI C++
Sbjct: 182 ------VKSTAVRVVDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSQPCDVWSIGCII 235
Query: 510 VELVTGESLYPIHENTEHMAMMQRINNEKFPKKMVEKMFFKVENKYGSIPTDLQTSVVKY 569
E G +L+ H+N EH+AMM+RI P +M+ K T KY
Sbjct: 236 FEYYVGFTLFQTHDNREHLAMMERILG-PIPSRMIRK-----------------TRKQKY 277
Query: 570 FDRQTGELRWPLRNSKGQVITKE-KSWKRILATCDRLDVFISKKLQMDYGSWLEIHWDMQ 628
F R G L W S G+ + + K +R L + +
Sbjct: 278 FYR--GRLDWDENTSAGRYVRENCKPLRRYLTS--------------------------E 309
Query: 629 LEDNWRLILSKNIDSRNIDKNVFMFWYYFVDLCRKMFEFDPTKRITAKEVIEHEWF 684
E++ +L DL M E++P KR+T E ++H +F
Sbjct: 310 AEEHHQLF----------------------DLIESMLEYEPAKRLTLGEALQHPFF 343
>Hs4502885_2 [T] KOG0671 LAMMER dual specificity kinases
Length = 367
Score = 229 bits (585), Expect = 8e-60
Identities = 141/431 (32%), Positives = 226/431 (51%), Gaps = 86/431 (19%)
Query: 257 SHQDKLRSMDRFKTDEEGHYVYQENDIFAKNRFQAMQLLGQGTFGKVVKCKDYLNDIT-V 315
S Q R+ + D+EGH V + D + + R++ + LG+GTFGKVV+C D+ + V
Sbjct: 2 SQQSSKRTGRSVEDDKEGHLVCRIGD-WLQERYEIVGNLGEGTFGKVVECLDHARGKSQV 60
Query: 316 AVKIIRAVDRYRQAAKTELRVLQTIKENDRSGQYQCLLLREFFDYKNHICLVTDLYGRSV 375
A+KIIR V +YR+AA+ E+ VL+ IKE D+ ++ C+L+ ++F++ H+C+ +L G++
Sbjct: 61 ALKIIRNVGKYREAARLEINVLKKIKEKDKENKFLCVLMSDWFNFHGHMCIAFELLGKNT 120
Query: 376 YDFMTNNGYARFPGSHVQAIGKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPM 435
++F+ N + +P HV+ + QL ++ FLH+ + HTDLKPENIL +
Sbjct: 121 FEFLKENNFQPYPLPHVRHMAYQLCHALRFLHENQLTHTDLKPENILFVNSE-------- 172
Query: 436 EIIDSLTERRKLASGGKRKILINPEVKLIDFGSAVFYNEYHPPVVSTRHYRAPEIVLGLG 495
++L K + K + N +++ DFGSA F +E+H +V+TRHYR PE++L LG
Sbjct: 173 --FETLYNEHKSC---EEKSVKNTSIRVADFGSATFDHEHHTTIVATRHYRPPEVILELG 227
Query: 496 WSFPCDIWSIACVLVELVTGESLYPIHENTEHMAMMQRINNEKFPKKMVEKMFFKVENKY 555
W+ PCD+WSI C+L E G +L+ HEN EH+ MM++I
Sbjct: 228 WAQPCDVWSIGCILFEYYRGFTLFQTHENREHLVMMEKI--------------------L 267
Query: 556 GSIPTDL--QTSVVKYFDRQTGELRWPLRNSKGQVITKEKSWKRILATCDRLDVFISKKL 613
G IP+ + +T KYF + G L W +S G+ + + C L ++
Sbjct: 268 GPIPSHMIHRTRKQKYFYK--GGLVWDENSSDGRYVKE---------NCKPLKSYM---- 312
Query: 614 QMDYGSWLEIHWDMQLEDNWRLILSKNIDSRNIDKNVFMFWYYFVDLCRKMFEFDPTKRI 673
L+D+ ++V +F DL R+M EFDP +RI
Sbjct: 313 ---------------LQDSL--------------EHVQLF-----DLMRRMLEFDPAQRI 338
Query: 674 TAKEVIEHEWF 684
T E + H +F
Sbjct: 339 TLAEALLHPFF 349
>SPAC2F7.03c [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 1087
Score = 169 bits (428), Expect = 1e-41
Identities = 107/358 (29%), Positives = 177/358 (48%), Gaps = 54/358 (15%)
Query: 260 DKLRSMDRFKT------DEEGHYVYQENDIFAKNRFQAMQLLGQGTFGKVVKCKDYLNDI 313
DK RS D + DE G Y D A R++ + LG+G+FG+V++C DY
Sbjct: 665 DKRRSADENTSSNFGFDDERGDYKVVLGDHIAY-RYEVVDFLGKGSFGQVLRCIDYETGK 723
Query: 314 TVAVKIIRAVDRYRQAAKTELRVLQTIKENDRSGQYQCLLLREFFDYKNHICLVTDLYGR 373
VA+KIIR R+ A E ++LQ I+E D +Y + + F +++H+C+ T+L G+
Sbjct: 724 LVALKIIRNKKRFHMQALVETKILQKIREWDPLDEYCMVQYTDHFYFRDHLCVATELLGK 783
Query: 374 SVYDFMTNNGYARFPGSHVQAIGKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSL 433
++Y+ + +NG+ P +++I +QL++ + L++ +IH DLKPENIL+C
Sbjct: 784 NLYELIKSNGFKGLPIVVIKSITRQLIQCLTLLNEKHVIHCDLKPENILLCHP------- 836
Query: 434 PMEIIDSLTERRKLASGGKRKILINPEVKLIDFGSAVFYNEYHPPVVSTRHYRAPEIVLG 493
+VK+IDFGS+ F E + +R YR+PE++LG
Sbjct: 837 -----------------------FKSQVKVIDFGSSCFEGECVYTYIQSRFYRSPEVILG 873
Query: 494 LGWSFPCDIWSIACVLVELVTGESLYPIHENTEHMAMMQRI----NNEKFPKKMVEKMFF 549
+G+ P D+WS+ C++ E+ TG L+P E +A + I ++ K +K+FF
Sbjct: 874 MGYGTPIDVWSLGCIIAEMYTGFPLFPGENEQEQLACIMEIFGPPDHSLIDKCSRKKVFF 933
Query: 550 KVENKYGSIPTDLQTSVVKYFDRQTGELRWPLRNSKGQVI-TKEKSWKRILATCDRLD 606
K + F G R P S QV+ K+ S+ ++ C + D
Sbjct: 934 DSSGK------------PRPFVSSKGVSRRPFSKSLHQVLQCKDVSFLSFISDCLKWD 979
>Hs4503429 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 553
Score = 154 bits (388), Expect = 6e-37
Identities = 106/421 (25%), Positives = 181/421 (42%), Gaps = 95/421 (22%)
Query: 271 DEEGHYVYQENDIFAKNRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAA 330
D +G Y++ D A R++ ++++G+G+FG+V + D+ VA+K++R R+ + A
Sbjct: 157 DADGAYIHVPRDHLAY-RYEVLKIIGKGSFGQVARVYDHKLRQYVALKMVRNEKRFHRQA 215
Query: 331 KTELRVLQTIKENDRSGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGS 390
E+R+L+ +K+ D++G + + E F ++NH+C+ +L +Y+ + N + F
Sbjct: 216 AEEIRILEHLKKQDKTGSMNVIHMLESFTFRNHVCMAFELLSIDLYELIKKNKFQGFSVQ 275
Query: 391 HVQAIGKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASG 450
V+ + +++S+ LH IIH DLKPENIL+
Sbjct: 276 LVRKFAQSILQSLDALHKNKIIHCDLKPENILL--------------------------- 308
Query: 451 GKRKILINPEVKLIDFGSAVFYNEYHPPVVSTRHYRAPEIVLGLGWSFPCDIWSIACVLV 510
K K+IDFGS+ F + + +R YRAPEI+LG +S P DIWS C+L
Sbjct: 309 ---KHHGRSSTKVIDFGSSCFEYQKLYTYIQSRFYRAPEIILGSRYSTPIDIWSFRCILA 365
Query: 511 ELVTGESLYPIHENTEHMAMMQRINNEKFPKKMVE----KMFFKVEN--KYGSIPTDLQT 564
EL+TG+ L+P + + +A M + PK + + K F + +Y S+ T
Sbjct: 366 ELLTGQPLFPGEDEGDQLACMMELLGMPPPKLLEQSKRAKYFINSKGIPRYCSVTTQADG 425
Query: 565 SVVKYFDRQTGELRWPLRNSKGQVITKEKSWKRILATCDRLDVFISKKLQMDYGSWLEIH 624
VV R R K + K W L CD
Sbjct: 426 RVVLVGGRS--------RRGKKRGPPGSKDWGTALKGCDD-------------------- 457
Query: 625 WDMQLEDNWRLILSKNIDSRNIDKNVFMFWYYFVDLCRKMFEFDPTKRITAKEVIEHEWF 684
Y F++ ++ +DP+ R+T + + H W
Sbjct: 458 ------------------------------YLFIEFLKRCLHWDPSARLTPAQALRHPWI 487
Query: 685 N 685
+
Sbjct: 488 S 488
>Hs20550209 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 520
Score = 152 bits (383), Expect = 2e-36
Identities = 81/264 (30%), Positives = 140/264 (52%), Gaps = 31/264 (11%)
Query: 271 DEEGHYVYQENDIFAKNRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAA 330
DE G Y+ +D A R++ ++ +G+G+FG+V KC D+ N+ VA+KIIR R+ Q A
Sbjct: 87 DEHGFYLKVLHDHIAY-RYEVLETIGKGSFGQVAKCLDHKNNELVALKIIRNKKRFHQQA 145
Query: 331 KTELRVLQTIKENDRSGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGS 390
EL++L+ +++ D+ Y + +++FF ++NH C+ +L G ++Y+ M NN + F S
Sbjct: 146 LMELKILEALRKKDKDNTYNVVHMKDFFYFRNHFCITFELLGINLYELMKNNNFQGFSLS 205
Query: 391 HVQAIGKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASG 450
V+ +++ + L IIH DLKPENI++ +
Sbjct: 206 IVRRFTLSVLKCLQMLSVEKIIHCDLKPENIVLYQKG----------------------- 242
Query: 451 GKRKILINPEVKLIDFGSAVFYNEYHPPVVSTRHYRAPEIVLGLGWSFPCDIWSIACVLV 510
VK+IDFGS+ + ++ + +R YR+PE++LG + D+WS+ C+
Sbjct: 243 -------QASVKVIDFGSSCYEHQKVYTYIQSRFYRSPEVILGHPYDVAIDMWSLGCITA 295
Query: 511 ELVTGESLYPIHENTEHMAMMQRI 534
EL TG L+P E +A + +
Sbjct: 296 ELYTGYPLFPGENEVEQLACIMEV 319
>Hs5922004 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 601
Score = 145 bits (366), Expect = 2e-34
Identities = 97/343 (28%), Positives = 170/343 (49%), Gaps = 53/343 (15%)
Query: 271 DEEGHYVYQENDIFAKNRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAA 330
D++G YV +D A R++ ++++G+G+FG+VVK D+ VA+K++R R+ + A
Sbjct: 205 DDQGSYVQVPHDHVAY-RYEVLKVIGKGSFGQVVKAYDHKVHQHVALKMVRNEKRFHRQA 263
Query: 331 KTELRVLQTIKENDRSGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGS 390
E+R+L+ +++ D+ + + E F ++NHIC+ +L ++Y+ + N + F
Sbjct: 264 AEEIRILEHLRKQDKDNTMNVIHMLENFTFRNHICMTFELLSMNLYELIKKNKFQGFSLP 323
Query: 391 HVQAIGKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASG 450
V+ +++ + LH IIH DLKPENIL+ +++ SG
Sbjct: 324 LVRKFAHSILQCLDALHKNRIIHCDLKPENILL--------------------KQQGRSG 363
Query: 451 GKRKILINPEVKLIDFGSAVFYNEYHPPVVSTRHYRAPEIVLGLGWSFPCDIWSIACVLV 510
+K+IDFGS+ + ++ + +R YRAPE++LG + P D+WS+ C+L
Sbjct: 364 ----------IKVIDFGSSCYEHQRVYTYIQSRFYRAPEVILGARYGMPIDMWSLGCILA 413
Query: 511 ELVTGESLYPIHENTEHMAMM---------QRINNEKFPKKMVEKMFFKVENKYGSIPTD 561
EL+TG L P + + +A M + ++ K K V K +Y ++ T
Sbjct: 414 ELLTGYPLLPGEDEGDQLACMIELLGMPSQKLLDASKRAKNFVSS---KGYPRYCTVTTL 470
Query: 562 LQTSVVKYFDR-QTGELRWPLRNSKGQVITKEKSWKRILATCD 603
SVV R + G+LR P + + W L CD
Sbjct: 471 SDGSVVLNGGRSRRGKLRGP---------PESREWGNALKGCD 504
>Hs4503427 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 528
Score = 145 bits (366), Expect = 2e-34
Identities = 97/343 (28%), Positives = 170/343 (49%), Gaps = 53/343 (15%)
Query: 271 DEEGHYVYQENDIFAKNRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAA 330
D++G YV +D A R++ ++++G+G+FG+VVK D+ VA+K++R R+ + A
Sbjct: 132 DDQGSYVQVPHDHVAY-RYEVLKVIGKGSFGQVVKAYDHKVHQHVALKMVRNEKRFHRQA 190
Query: 331 KTELRVLQTIKENDRSGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGS 390
E+R+L+ +++ D+ + + E F ++NHIC+ +L ++Y+ + N + F
Sbjct: 191 AEEIRILEHLRKQDKDNTMNVIHMLENFTFRNHICMTFELLSMNLYELIKKNKFQGFSLP 250
Query: 391 HVQAIGKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASG 450
V+ +++ + LH IIH DLKPENIL+ +++ SG
Sbjct: 251 LVRKFAHSILQCLDALHKNRIIHCDLKPENILL--------------------KQQGRSG 290
Query: 451 GKRKILINPEVKLIDFGSAVFYNEYHPPVVSTRHYRAPEIVLGLGWSFPCDIWSIACVLV 510
+K+IDFGS+ + ++ + +R YRAPE++LG + P D+WS+ C+L
Sbjct: 291 ----------IKVIDFGSSCYEHQRVYTYIQSRFYRAPEVILGARYGMPIDMWSLGCILA 340
Query: 511 ELVTGESLYPIHENTEHMAMM---------QRINNEKFPKKMVEKMFFKVENKYGSIPTD 561
EL+TG L P + + +A M + ++ K K V K +Y ++ T
Sbjct: 341 ELLTGYPLLPGEDEGDQLACMIELLGMPSQKLLDASKRAKNFVSS---KGYPRYCTVTTL 397
Query: 562 LQTSVVKYFDR-QTGELRWPLRNSKGQVITKEKSWKRILATCD 603
SVV R + G+LR P + + W L CD
Sbjct: 398 SDGSVVLNGGRSRRGKLRGP---------PESREWGNALKGCD 431
>7298142 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 722
Score = 143 bits (361), Expect = 8e-34
Identities = 77/264 (29%), Positives = 140/264 (52%), Gaps = 31/264 (11%)
Query: 271 DEEGHYVYQENDIFAKNRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAA 330
D+ G+Y E+D A R++ ++++G+G+FG+V++ D+ + VA+KIIR R+ A
Sbjct: 181 DDNGNYKIIEHDHIAF-RYEILEVIGKGSFGQVIRALDHKTNTHVAIKIIRNKKRFLNQA 239
Query: 331 KTELRVLQTIKENDRSGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGS 390
EL +L ++E D G + + + ++ ++ H+C+ +L ++Y+ + N Y F S
Sbjct: 240 VVELNILDELREKDADGSHNVIHMLDYTYFRKHLCITFELMSLNLYELIKKNNYNGFSMS 299
Query: 391 HVQAIGKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASG 450
++ +V+ + L+ IIH DLKPENIL+ ++R +S
Sbjct: 300 LIRRFCNSIVKCLRLLYKENIIHCDLKPENILL-------------------KQRGSSS- 339
Query: 451 GKRKILINPEVKLIDFGSAVFYNEYHPPVVSTRHYRAPEIVLGLGWSFPCDIWSIACVLV 510
+K+IDFGS+ + + + +R YR+PE++LGL + D+WS+ C+L
Sbjct: 340 ----------IKVIDFGSSCYVDRKIYTYIQSRFYRSPEVILGLQYGTAIDMWSLGCILA 389
Query: 511 ELVTGESLYPIHENTEHMAMMQRI 534
EL TG L+P E +A + +
Sbjct: 390 ELYTGFPLFPGENEVEQLACIMEV 413
>ECU11g0180 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 405
Score = 141 bits (355), Expect = 4e-33
Identities = 91/293 (31%), Positives = 146/293 (49%), Gaps = 42/293 (14%)
Query: 271 DEEGHYVYQENDIFAKNRFQA---MQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYR 327
+EE V D AKN+ Q + +LG GTFG+VV+C + VA+K+++ +Y
Sbjct: 19 NEEFDLVMARGDYLAKNKSQKYMIIDMLGTGTFGQVVRCVGSDGE-EVAIKVVKNQPKYY 77
Query: 328 QAAKTELRVLQTIKENDRSGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARF 387
E+R+L + N+ + ++ + +++ F YK H+C+V +L GR++Y F+ +
Sbjct: 78 NYEMNEVRILHKLLYNNLNDRF--VTIKDVFMYKQHLCIVEELLGRNLYTFLKMTRFKGL 135
Query: 388 PGSHVQAIGKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKL 447
++ I Q++ + L LGIIH DLKPENILI D
Sbjct: 136 DHPTLRTILHQILEGMVQLSLLGIIHCDLKPENILIADYDTF------------------ 177
Query: 448 ASGGKRKILINPEVKLIDFGSAVFYNEYHPPVVSTRHYRAPEIVLGLGWSFPCDIWSIAC 507
++K+IDFGSAV + V +R+YRAPE++LG+ + CDIWS+ C
Sbjct: 178 ------------KIKIIDFGSAVTSPQGSHFYVQSRYYRAPEVILGIPYGSSCDIWSLGC 225
Query: 508 VLVELVTGESLYPIHENTEHMAMMQRINNEKFPKKMVE-----KMFFKVENKY 555
+ EL G L+P +N + + + + P M+E FF+ EN Y
Sbjct: 226 IGYELYVGHPLFPGKDNMDQIGRIHGLFG-SLPMFMLEHGKNSSTFFEKENGY 277
>Hs13430860 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 1198
Score = 140 bits (352), Expect = 9e-33
Identities = 106/420 (25%), Positives = 190/420 (45%), Gaps = 81/420 (19%)
Query: 270 TDEEGHYVYQENDIFAK--NRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYR 327
++ EG Y ++++ N ++ ++ LG+GTFG+VVKC + VA+KI++ Y
Sbjct: 178 SNSEGDYQLVQHEVLCSMTNTYEVLEFLGRGTFGQVVKCWKRGTNEIVAIKILKNRPSYA 237
Query: 328 QAAKTELRVLQTIKENDRSGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARF 387
+ + E+ +L + + + Y + E F +KNH CLV ++ +++YDF+ N ++
Sbjct: 238 RQGQIEVSILARLS-TESADDYNFVRAYECFQHKNHTCLVFEMLEQNLYDFLKQNKFSPL 296
Query: 388 PGSHVQAIGKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKL 447
P +++ + +Q+ ++ L LG+IH DLKPENI++ D +
Sbjct: 297 PLKYIRPVLQQVATALMKLKSLGLIHADLKPENIMLVDPSRQPY---------------- 340
Query: 448 ASGGKRKILINPEVKLIDFGSAVFYNE-YHPPVVSTRHYRAPEIVLGLGWSFPCDIWSIA 506
VK+IDFGSA ++ + +R+YRAPEI+LGL + D+WS+
Sbjct: 341 ------------RVKVIDFGSASHVSKAVCSTYLQSRYYRAPEIILGLPFCEAIDMWSLG 388
Query: 507 CVLVELVTGESLYPIHENTEHMAMMQRINNEKFPKKMVEKMFFKVENKYGSIPTDLQTSV 566
CV+ EL G LYP + + + + + P + + T
Sbjct: 389 CVIAELFLGWPLYPGASEYDQIRYISQ--TQGLPAEYL---------------LSAGTKT 431
Query: 567 VKYFDRQTGE--LRWPLR---NSKGQVITKEKSWKRILATCDRLDVFISKKLQMDYGSWL 621
++F+R T W L+ + + + K K ++ + C +D + +
Sbjct: 432 TRFFNRDTDSPYPLWRLKTPDDHEAETGIKSKEARKYIFNC------------LDDMAQV 479
Query: 622 EIHWDMQLEDNWRLILSKNIDSRNIDKNVFMFWYYFVDLCRKMFEFDPTKRITAKEVIEH 681
+ D++ D +L + D R F+DL +KM D KRIT E + H
Sbjct: 480 NMTTDLEGSD----MLVEKADRRE-----------FIDLLKKMLTIDADKRITPIETLNH 524
>YJL141c [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 807
Score = 139 bits (350), Expect = 1e-32
Identities = 75/249 (30%), Positives = 130/249 (52%), Gaps = 34/249 (13%)
Query: 276 YVYQENDIFA---KNRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKT 332
Y+ ND+ ++ + +LGQGTFG+VVKC++ L +AVK++++ Y + T
Sbjct: 353 YILYVNDVLGVEQNRKYLVLDILGQGTFGQVVKCQNLLTKEILAVKVVKSRTEYLTQSIT 412
Query: 333 ELRVLQTIKEN-DRSGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSH 391
E ++L+ + + D + ++ L + + F +KNH+CLV +L ++Y+ + N +
Sbjct: 413 EAKILELLNQKIDPTNKHHFLRMYDSFVHKNHLCLVFELLSNNLYELLKQNKFHGLSIQL 472
Query: 392 VQAIGKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGG 451
++ Q++ S+C L + +IH DLKPENIL+C
Sbjct: 473 IRTFTTQILDSLCVLKESKLIHCDLKPENILLCAPD------------------------ 508
Query: 452 KRKILINPEVKLIDFGSAVFYNEYHPPVVSTRHYRAPEIVLGLGWSFPCDIWSIACVLVE 511
PE+K+IDFGS+ + +R YRAPEI+LG+ +S D+WS+ C++ E
Sbjct: 509 ------KPELKIIDFGSSCEEARTVYTYIQSRFYRAPEIILGIPYSTSIDMWSLGCIVAE 562
Query: 512 LVTGESLYP 520
L G ++P
Sbjct: 563 LFLGIPIFP 571
>CE23751 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 796
Score = 139 bits (350), Expect = 1e-32
Identities = 76/273 (27%), Positives = 143/273 (51%), Gaps = 31/273 (11%)
Query: 271 DEEGHYVYQENDIFAKNRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAA 330
DE G Y +D A R++ ++++G+G+FG+V+K D+ VA+K++R R+ + A
Sbjct: 444 DENGSYQLVVHDHIAY-RYEVLKVIGKGSFGQVIKAFDHKYQQYVALKLVRNEKRFHRQA 502
Query: 331 KTELRVLQTIKENDRSGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGS 390
E+R+L ++ D G + + + ++F+++NH C+ +L ++Y+ + N + F
Sbjct: 503 DEEIRILDHLRRQDSDGTHNIIHMLDYFNFRNHKCITFELLSINLYELIKRNKFQGFSLM 562
Query: 391 HVQAIGKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASG 450
V+ ++ + L +IH DLKPEN+L+ +++ SG
Sbjct: 563 LVRKFAYSMLLCLDLLQKNRLIHCDLKPENVLL--------------------KQQGRSG 602
Query: 451 GKRKILINPEVKLIDFGSAVFYNEYHPPVVSTRHYRAPEIVLGLGWSFPCDIWSIACVLV 510
+K+IDFGS+ F ++ + +R YRAPE++LG + P D+WS+ C+L
Sbjct: 603 ----------IKVIDFGSSCFDDQRIYTYIQSRFYRAPEVILGTKYGMPIDMWSLGCILA 652
Query: 511 ELVTGESLYPIHENTEHMAMMQRINNEKFPKKM 543
EL+TG L P + + +A++ + PK +
Sbjct: 653 ELLTGYPLLPGEDENDQLALIIELLGMPPPKSL 685
>CE19878 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 817
Score = 139 bits (350), Expect = 1e-32
Identities = 76/273 (27%), Positives = 143/273 (51%), Gaps = 31/273 (11%)
Query: 271 DEEGHYVYQENDIFAKNRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAA 330
DE G Y +D A R++ ++++G+G+FG+V+K D+ VA+K++R R+ + A
Sbjct: 444 DENGSYQLVVHDHIAY-RYEVLKVIGKGSFGQVIKAFDHKYQQYVALKLVRNEKRFHRQA 502
Query: 331 KTELRVLQTIKENDRSGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGS 390
E+R+L ++ D G + + + ++F+++NH C+ +L ++Y+ + N + F
Sbjct: 503 DEEIRILDHLRRQDSDGTHNIIHMLDYFNFRNHKCITFELLSINLYELIKRNKFQGFSLM 562
Query: 391 HVQAIGKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASG 450
V+ ++ + L +IH DLKPEN+L+ +++ SG
Sbjct: 563 LVRKFAYSMLLCLDLLQKNRLIHCDLKPENVLL--------------------KQQGRSG 602
Query: 451 GKRKILINPEVKLIDFGSAVFYNEYHPPVVSTRHYRAPEIVLGLGWSFPCDIWSIACVLV 510
+K+IDFGS+ F ++ + +R YRAPE++LG + P D+WS+ C+L
Sbjct: 603 ----------IKVIDFGSSCFDDQRIYTYIQSRFYRAPEVILGTKYGMPIDMWSLGCILA 652
Query: 511 ELVTGESLYPIHENTEHMAMMQRINNEKFPKKM 543
EL+TG L P + + +A++ + PK +
Sbjct: 653 ELLTGYPLLPGEDENDQLALIIELLGMPPPKSL 685
>CE05897 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 508
Score = 139 bits (350), Expect = 1e-32
Identities = 76/273 (27%), Positives = 143/273 (51%), Gaps = 31/273 (11%)
Query: 271 DEEGHYVYQENDIFAKNRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAA 330
DE G Y +D A R++ ++++G+G+FG+V+K D+ VA+K++R R+ + A
Sbjct: 150 DENGSYQLVVHDHIAY-RYEVLKVIGKGSFGQVIKAFDHKYQQYVALKLVRNEKRFHRQA 208
Query: 331 KTELRVLQTIKENDRSGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGS 390
E+R+L ++ D G + + + ++F+++NH C+ +L ++Y+ + N + F
Sbjct: 209 DEEIRILDHLRRQDSDGTHNIIHMLDYFNFRNHKCITFELLSINLYELIKRNKFQGFSLM 268
Query: 391 HVQAIGKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASG 450
V+ ++ + L +IH DLKPEN+L+ +++ SG
Sbjct: 269 LVRKFAYSMLLCLDLLQKNRLIHCDLKPENVLL--------------------KQQGRSG 308
Query: 451 GKRKILINPEVKLIDFGSAVFYNEYHPPVVSTRHYRAPEIVLGLGWSFPCDIWSIACVLV 510
+K+IDFGS+ F ++ + +R YRAPE++LG + P D+WS+ C+L
Sbjct: 309 ----------IKVIDFGSSCFDDQRIYTYIQSRFYRAPEVILGTKYGMPIDMWSLGCILA 358
Query: 511 ELVTGESLYPIHENTEHMAMMQRINNEKFPKKM 543
EL+TG L P + + +A++ + PK +
Sbjct: 359 ELLTGYPLLPGEDENDQLALIIELLGMPPPKSL 391
>At3g53640 [A] KOG0670 U4/U6-associated splicing factor PRP4
Length = 642
Score = 139 bits (350), Expect = 1e-32
Identities = 90/285 (31%), Positives = 146/285 (50%), Gaps = 39/285 (13%)
Query: 271 DEEGHYVYQENDIFAKNRFQAMQLLGQGTFGKVVKCKDYLNDI----TVAVKIIRAVDRY 326
D EG+Y YQ ++ +R++ M G+G F VV+ KD ++ VA+KIIR +
Sbjct: 306 DAEGYYSYQLGELL-DDRYEIMATHGKGVFSTVVRAKDTKPELGEPEEVAIKIIRKNETM 364
Query: 327 RQAAKTELRVLQTIKENDRSGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGY-A 385
+A + E+R+L+ + +D ++ C+ L F+Y+NH+CLV + ++ + + G
Sbjct: 365 HKAGQAEIRILKKLVCSDPENKHHCVRLLSTFEYRNHLCLVFESLHLNLREVVKKIGVNI 424
Query: 386 RFPGSHVQAIGKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERR 445
V+ +QL S+ L + G++H D+KP+NIL + E R
Sbjct: 425 GLKLYDVRVYAEQLFISLKHLKNCGVLHCDIKPDNIL------------------MNEGR 466
Query: 446 KLASGGKRKILINPEVKLIDFGSAVFYNEYH-PPVVSTRHYRAPEIVLGLGWSFPCDIWS 504
+ +KL DFGSA+F E P + +R YRAPEI+LGL + P DIWS
Sbjct: 467 NM-------------LKLCDFGSAMFAGENQVTPYLVSRFYRAPEIILGLPYDHPLDIWS 513
Query: 505 IACVLVELVTGESLYPIHENTEHMAMMQRINNEKFPKKMVEKMFF 549
+ C L EL +G+ ++P N + + + + FPKKM+ K F
Sbjct: 514 VGCCLYELYSGKIMFPGSTNNDMLRLHMELKG-PFPKKMLRKGAF 557
>7291976 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 1320
Score = 139 bits (349), Expect = 2e-32
Identities = 111/434 (25%), Positives = 196/434 (44%), Gaps = 77/434 (17%)
Query: 256 GSHQDKLRSMDRFKTDEEGHYVYQENDIF--AKNRFQAMQLLGQGTFGKVVKCKDYLNDI 313
G H + R + +G Y ++++ ++ ++ LG+GTFG+VVKC
Sbjct: 157 GGHANTQPPSKRSSSGADGDYQLVQHEVLYSLSAEYEVLEFLGRGTFGQVVKCWKRGTSE 216
Query: 314 TVAVKIIRAVDRYRQAAKTELRVLQTIKENDRSGQYQCLLLREFFDYKNHICLVTDLYGR 373
VA+KI++ Y + + E+ +L + + + + ++ + E F +KNH CLV ++ +
Sbjct: 217 IVAIKILKNHPSYARQGQIEVSILSRLSQ-ENADEFNFVRAFECFQHKNHTCLVFEMLEQ 275
Query: 374 SVYDFMTNNGYARFPGSHVQAIGKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSL 433
++YDF+ N ++ P +++ I +Q++ ++ L LG+IH DLKPENI++ D V Q
Sbjct: 276 NLYDFLKQNKFSPLPLKYIRPILEQVLTALLKLKQLGLIHADLKPENIMLVDP--VRQPY 333
Query: 434 PMEIIDSLTERRKLASGGKRKILINPEVKLIDFGSAVFYNE-YHPPVVSTRHYRAPEIVL 492
VK+IDFGSA ++ + +R+YRAPEI+L
Sbjct: 334 --------------------------RVKVIDFGSASHVSKTVCNTYLQSRYYRAPEIIL 367
Query: 493 GLGWSFPCDIWSIACVLVELVTGESLYPIHENTEHMAMMQRINNEKFPKKMVEKMFFKVE 552
GL + D+WS+ CV+ EL G LYP + + + + E
Sbjct: 368 GLPFCEAIDMWSLGCVVAELFLGWPLYPGSSEFDQIRYISQTQG------------LPTE 415
Query: 553 NKYGSIPTDLQTSVVKYFDRQTGELRWPLRNS---KGQVITKEKSWKRILATCDRLDVFI 609
+ S +TS Y D + W L+ + + + TK K ++ + C LD
Sbjct: 416 HMLNSAS---KTSKFFYRDVDSTYPFWRLKTTEEHEAETNTKSKEARKYIFNC--LD--- 467
Query: 610 SKKLQMDYGSWLEIHWDMQLEDNWRLILSKNIDSRNIDKNVFMFWYYFVDLCRKMFEFDP 669
D G +++ LE +L++ D R F+DL ++M D
Sbjct: 468 ------DIG---QVNVPTDLEGG--QLLAEKTDRRE-----------FIDLLKRMLTIDQ 505
Query: 670 TKRITAKEVIEHEW 683
+R+T E + H +
Sbjct: 506 ERRLTPAEALNHSF 519
>Hs5922001 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 601
Score = 138 bits (347), Expect = 3e-32
Identities = 95/339 (28%), Positives = 165/339 (48%), Gaps = 52/339 (15%)
Query: 250 KKSPLLGSHQDKLRSMDRFKTDEEGH-YVYQENDIFAKNRFQAMQLLGQGTFGKVVKCKD 308
+++P S K + + D++ H Y+ + + + + R++ L+G+G+FG+VVK D
Sbjct: 72 QQAPPQDSSNKKEKKVLNHGYDDDNHDYIVRSGERWLE-RYEIDSLIGKGSFGQVVKAYD 130
Query: 309 YLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKENDRSGQYQCLLLREFFDYKNHICLVT 368
+ VA+KII+ + A+ ELR+L+ + ++D +Y + L+ F ++NH+CLV
Sbjct: 131 HQTQELVAIKIIKNKKAFLNQAQIELRLLELMNQHDTEMKYYIVHLKRHFMFRNHLCLVF 190
Query: 369 DLYGRSVYDFMTNNGYARFPGSHVQAIGKQLVRSVCFLH--DLGIIHTDLKPENILICDE 426
+L ++YD + N + + + + +QL ++ FL +L IIH DLKPENIL+C+
Sbjct: 191 ELLSYNLYDLLRNTHFRGVSLNLTRKLAQQLCTALLFLATPELSIIHCDLKPENILLCNP 250
Query: 427 TCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKLIDFGSAVFYNEYHPPVVSTRHYR 486
KR +K++DFGS+ + + +R YR
Sbjct: 251 -------------------------KRSA-----IKIVDFGSSCQLGQRIYQYIQSRFYR 280
Query: 487 APEIVLGLGWSFPCDIWSIACVLVELVTGESLYPIHENTEHMAMMQRINNEKFPKKMVEK 546
+PE++LG + D+WS+ C+LVE+ TGE P+ + + M RI
Sbjct: 281 SPEVLLGTPYDLAIDMWSLGCILVEMHTGE---PLFSGSNEVDQMNRI------------ 325
Query: 547 MFFKVENKYGSIPTDLQTSVVKYFDRQTGELRWPLRNSK 585
+V + D KYF+R G W LR +K
Sbjct: 326 --VEVLGIPPAAMLDQAPKARKYFERLPGG-GWTLRRTK 361
>Hs5921999 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 589
Score = 138 bits (347), Expect = 3e-32
Identities = 95/339 (28%), Positives = 165/339 (48%), Gaps = 52/339 (15%)
Query: 250 KKSPLLGSHQDKLRSMDRFKTDEEGH-YVYQENDIFAKNRFQAMQLLGQGTFGKVVKCKD 308
+++P S K + + D++ H Y+ + + + + R++ L+G+G+FG+VVK D
Sbjct: 72 QQAPPQDSSNKKEKKVLNHGYDDDNHDYIVRSGERWLE-RYEIDSLIGKGSFGQVVKAYD 130
Query: 309 YLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKENDRSGQYQCLLLREFFDYKNHICLVT 368
+ VA+KII+ + A+ ELR+L+ + ++D +Y + L+ F ++NH+CLV
Sbjct: 131 HQTQELVAIKIIKNKKAFLNQAQIELRLLELMNQHDTEMKYYIVHLKRHFMFRNHLCLVF 190
Query: 369 DLYGRSVYDFMTNNGYARFPGSHVQAIGKQLVRSVCFLH--DLGIIHTDLKPENILICDE 426
+L ++YD + N + + + + +QL ++ FL +L IIH DLKPENIL+C+
Sbjct: 191 ELLSYNLYDLLRNTHFRGVSLNLTRKLAQQLCTALLFLATPELSIIHCDLKPENILLCNP 250
Query: 427 TCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKLIDFGSAVFYNEYHPPVVSTRHYR 486
KR +K++DFGS+ + + +R YR
Sbjct: 251 -------------------------KRSA-----IKIVDFGSSCQLGQRIYQYIQSRFYR 280
Query: 487 APEIVLGLGWSFPCDIWSIACVLVELVTGESLYPIHENTEHMAMMQRINNEKFPKKMVEK 546
+PE++LG + D+WS+ C+LVE+ TGE P+ + + M RI
Sbjct: 281 SPEVLLGTPYDLAIDMWSLGCILVEMHTGE---PLFSGSNEVDQMNRI------------ 325
Query: 547 MFFKVENKYGSIPTDLQTSVVKYFDRQTGELRWPLRNSK 585
+V + D KYF+R G W LR +K
Sbjct: 326 --VEVLGIPPAAMLDQAPKARKYFERLPGG-GWTLRRTK 361
>Hs4758222 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 629
Score = 138 bits (347), Expect = 3e-32
Identities = 95/339 (28%), Positives = 165/339 (48%), Gaps = 52/339 (15%)
Query: 250 KKSPLLGSHQDKLRSMDRFKTDEEGH-YVYQENDIFAKNRFQAMQLLGQGTFGKVVKCKD 308
+++P S K + + D++ H Y+ + + + + R++ L+G+G+FG+VVK D
Sbjct: 72 QQAPPQDSSNKKEKKVLNHGYDDDNHDYIVRSGERWLE-RYEIDSLIGKGSFGQVVKAYD 130
Query: 309 YLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKENDRSGQYQCLLLREFFDYKNHICLVT 368
+ VA+KII+ + A+ ELR+L+ + ++D +Y + L+ F ++NH+CLV
Sbjct: 131 HQTQELVAIKIIKNKKAFLNQAQIELRLLELMNQHDTEMKYYIVHLKRHFMFRNHLCLVF 190
Query: 369 DLYGRSVYDFMTNNGYARFPGSHVQAIGKQLVRSVCFLH--DLGIIHTDLKPENILICDE 426
+L ++YD + N + + + + +QL ++ FL +L IIH DLKPENIL+C+
Sbjct: 191 ELLSYNLYDLLRNTHFRGVSLNLTRKLAQQLCTALLFLATPELSIIHCDLKPENILLCNP 250
Query: 427 TCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKLIDFGSAVFYNEYHPPVVSTRHYR 486
KR +K++DFGS+ + + +R YR
Sbjct: 251 -------------------------KRSA-----IKIVDFGSSCQLGQRIYQYIQSRFYR 280
Query: 487 APEIVLGLGWSFPCDIWSIACVLVELVTGESLYPIHENTEHMAMMQRINNEKFPKKMVEK 546
+PE++LG + D+WS+ C+LVE+ TGE P+ + + M RI
Sbjct: 281 SPEVLLGTPYDLAIDMWSLGCILVEMHTGE---PLFSGSNEVDQMNRI------------ 325
Query: 547 MFFKVENKYGSIPTDLQTSVVKYFDRQTGELRWPLRNSK 585
+V + D KYF+R G W LR +K
Sbjct: 326 --VEVLGIPPAAMLDQAPKARKYFERLPGG-GWTLRRTK 361
>CE04430 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 821
Score = 135 bits (341), Expect = 2e-31
Identities = 83/259 (32%), Positives = 138/259 (53%), Gaps = 33/259 (12%)
Query: 266 DRFKTDEEGHYVYQENDIFAK---NRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRA 322
+R K EG Y +N++ N+++ ++ LG+GTFG+VVK VA+KI++
Sbjct: 96 NRGKVSGEGEYQLIKNEVLCSPYGNQYEVLEFLGKGTFGQVVKAWKKGTSEIVAIKILKK 155
Query: 323 VDRYRQAAKTELRVLQTIKENDRSGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNN 382
Y + + E+ +L + N+ S ++ + E F++K+H CLV ++ +++YDF+ N
Sbjct: 156 HPSYARQGQIEVSILSRLS-NENSEEFNFVRAFECFNHKSHTCLVFEMLEQNLYDFLKQN 214
Query: 383 GYARFPGSHVQAIGKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLT 442
+ P + ++ I Q++ ++ L LG+IH DLKPENI++ D Q P
Sbjct: 215 KFMPLPLNAIRPILFQVLTALLKLKSLGLIHADLKPENIMLVD----PQQQPY------- 263
Query: 443 ERRKLASGGKRKILINPEVKLIDFGSAVFYNE-YHPPVVSTRHYRAPEIVLGLGWSFPCD 501
VK+IDFGSA ++ + +R+YRAPEI+LGL ++ D
Sbjct: 264 -----------------RVKVIDFGSASHRSKAVTNTYLQSRYYRAPEIILGLPFNESID 306
Query: 502 IWSIACVLVELVTGESLYP 520
+WS+ CV+ EL G LYP
Sbjct: 307 MWSLGCVIAELFLGWPLYP 325
>Hs11386209 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 1215
Score = 135 bits (340), Expect = 2e-31
Identities = 113/426 (26%), Positives = 195/426 (45%), Gaps = 83/426 (19%)
Query: 270 TDEEGHYVYQENDIFA--KNRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYR 327
T EG Y ++++ KN ++ + LG+GTFG+VVKC + VA+KI++ Y
Sbjct: 176 TTGEGDYQLVQHEVLCSMKNTYEVLDFLGRGTFGQVVKCWKRGTNEIVAIKILKNHPSYA 235
Query: 328 QAAKTELRVLQTIKENDRSGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARF 387
+ + E+ +L + + + +Y + E F ++NH CLV ++ +++YDF+ N ++
Sbjct: 236 RQGQIEVSILARLS-TENADEYNFVRAYECFQHRNHTCLVFEMLEQNLYDFLKQNKFSPL 294
Query: 388 PGSHVQAIGKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKL 447
P ++ I +Q+ ++ L LG+IH DLKPENI++ D V Q
Sbjct: 295 PLKVIRPILQQVATALKKLKSLGLIHADLKPENIMLVDP--VRQPY-------------- 338
Query: 448 ASGGKRKILINPEVKLIDFGSAVFYNE-YHPPVVSTRHYRAPEIVLGLGWSFPCDIWSIA 506
VK+IDFGSA ++ + +R+YRAPEI+LGL + D+WS+
Sbjct: 339 ------------RVKVIDFGSASHVSKTVCSTYLQSRYYRAPEIILGLPFCEAIDMWSLG 386
Query: 507 CVLVELVTGESLYP---IHENTEHMAMMQRINNEKFPKKMVEKMFFKVENKYGSIPTDLQ 563
CV+ EL G LYP ++ +++ Q + E+ ++
Sbjct: 387 CVIAELFLGWPLYPGALEYDQIRYISQTQGLPGEQL--------------------LNVG 426
Query: 564 TSVVKYFDRQT--GELRWPLRN-SKGQVITKEKSWKRILATCDRLDVFISKKLQMDYGSW 620
T ++F ++T W L+ + + T KS + R +F S +D +
Sbjct: 427 TKSTRFFCKETDMSHSGWRLKTLEEHEAETGMKSKEA------RKYIFNS----LDDVAH 476
Query: 621 LEIHWDMQLEDNWRLILSKNIDSRNIDKNVFMFWYYFVDLCRKMFEFDPTKRITAKEVIE 680
+ D++ D +L++ D R FV L +KM D RIT E +
Sbjct: 477 VNTVMDLEGSD----LLAEKADRRE-----------FVSLLKKMLLIDADLRITPAETLN 521
Query: 681 HEWFNI 686
H + N+
Sbjct: 522 HPFVNM 527
>CE05686 [A] KOG0670 U4/U6-associated splicing factor PRP4
Length = 775
Score = 135 bits (339), Expect = 3e-31
Identities = 89/284 (31%), Positives = 138/284 (48%), Gaps = 39/284 (13%)
Query: 271 DEEGHYVYQENDIFAKNRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAA 330
D EG+Y + ++ R++ + G G FG V +C D TVAVKIIR + +
Sbjct: 438 DVEGYYRVRIGELL-DTRYRVVGFTGAGVFGNVCRCNDQTKGNTVAVKIIRNNEVMYKTG 496
Query: 331 KTELRVLQTIKENDRSGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGS 390
EL VL+ + E D+ +Y CL L F + NH+CLV + ++ + + Y + G
Sbjct: 497 LRELEVLRKLNEADKEDKYHCLRLFRTFKHHNHLCLVFENLSMNLRELLKK--YGQKDGL 554
Query: 391 HVQAI---GKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKL 447
H++A+ +QL+ ++ L L +H D+KP+NIL+ +
Sbjct: 555 HLKAVRSYAQQLLLALRLLKKLEFVHADIKPDNILVNESKLT------------------ 596
Query: 448 ASGGKRKILINPEVKLIDFGSAVFYNEYH-PPVVSTRHYRAPEIVLGLGWSFPCDIWSIA 506
+KL DFGSA NE P + +R YRAPEI+LG+ + D+WS+A
Sbjct: 597 -------------LKLCDFGSAGRVNEQELAPYLVSRFYRAPEIMLGVRHDYAIDLWSVA 643
Query: 507 CVLVELVTGESLYPIHENTEHMAMMQRINNEKFPKKMVEKMFFK 550
L E+ TG+ ++P N HM + K+P K+V K FK
Sbjct: 644 VTLYEVYTGKIMFPGRTN-NHMLKLFTDVKGKYPNKLVRKSQFK 686
>Hs18765758 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 763
Score = 134 bits (336), Expect = 6e-31
Identities = 76/265 (28%), Positives = 141/265 (52%), Gaps = 33/265 (12%)
Query: 257 SHQDKLRSMDRFKTDEEGHYVYQENDIFAKNRFQAMQLLGQGTFGKVVKCKDYLNDITVA 316
SH+ + + + D+ Y+ + + + +R++ L+G+G+FG+VVK D + VA
Sbjct: 128 SHKKERKVYNDGYDDDNYDYIVKNGEKWM-DRYEIDSLIGKGSFGQVVKAYDRVEQEWVA 186
Query: 317 VKIIRAVDRYRQAAKTELRVLQTIKENDRSGQYQCLLLREFFDYKNHICLVTDLYGRSVY 376
+KII+ + A+ E+R+L+ + ++D +Y + L+ F ++NH+CLV ++ ++Y
Sbjct: 187 IKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEMLSYNLY 246
Query: 377 DFMTNNGYARFPGSHVQAIGKQLVRSVCFLH--DLGIIHTDLKPENILICDETCVEQSLP 434
D + N + + + +Q+ ++ FL +L IIH DLKPENIL+C+
Sbjct: 247 DLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNP-------- 298
Query: 435 MEIIDSLTERRKLASGGKRKILINPEVKLIDFGSAVFYNEYHPPVVSTRHYRAPEIVLGL 494
KR +K++DFGS+ + + +R YR+PE++LG+
Sbjct: 299 -----------------KRSA-----IKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGM 336
Query: 495 GWSFPCDIWSIACVLVELVTGESLY 519
+ D+WS+ C+LVE+ TGE L+
Sbjct: 337 PYDLAIDMWSLGCILVEMHTGEPLF 361
>Hs18765756 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 529
Score = 134 bits (336), Expect = 6e-31
Identities = 76/265 (28%), Positives = 141/265 (52%), Gaps = 33/265 (12%)
Query: 257 SHQDKLRSMDRFKTDEEGHYVYQENDIFAKNRFQAMQLLGQGTFGKVVKCKDYLNDITVA 316
SH+ + + + D+ Y+ + + + +R++ L+G+G+FG+VVK D + VA
Sbjct: 128 SHKKERKVYNDGYDDDNYDYIVKNGEKWM-DRYEIDSLIGKGSFGQVVKAYDRVEQEWVA 186
Query: 317 VKIIRAVDRYRQAAKTELRVLQTIKENDRSGQYQCLLLREFFDYKNHICLVTDLYGRSVY 376
+KII+ + A+ E+R+L+ + ++D +Y + L+ F ++NH+CLV ++ ++Y
Sbjct: 187 IKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEMLSYNLY 246
Query: 377 DFMTNNGYARFPGSHVQAIGKQLVRSVCFLH--DLGIIHTDLKPENILICDETCVEQSLP 434
D + N + + + +Q+ ++ FL +L IIH DLKPENIL+C+
Sbjct: 247 DLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNP-------- 298
Query: 435 MEIIDSLTERRKLASGGKRKILINPEVKLIDFGSAVFYNEYHPPVVSTRHYRAPEIVLGL 494
KR +K++DFGS+ + + +R YR+PE++LG+
Sbjct: 299 -----------------KRSA-----IKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGM 336
Query: 495 GWSFPCDIWSIACVLVELVTGESLY 519
+ D+WS+ C+LVE+ TGE L+
Sbjct: 337 PYDLAIDMWSLGCILVEMHTGEPLF 361
>Hs18765754 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 540
Score = 134 bits (336), Expect = 6e-31
Identities = 76/265 (28%), Positives = 141/265 (52%), Gaps = 33/265 (12%)
Query: 257 SHQDKLRSMDRFKTDEEGHYVYQENDIFAKNRFQAMQLLGQGTFGKVVKCKDYLNDITVA 316
SH+ + + + D+ Y+ + + + +R++ L+G+G+FG+VVK D + VA
Sbjct: 128 SHKKERKVYNDGYDDDNYDYIVKNGEKWM-DRYEIDSLIGKGSFGQVVKAYDRVEQEWVA 186
Query: 317 VKIIRAVDRYRQAAKTELRVLQTIKENDRSGQYQCLLLREFFDYKNHICLVTDLYGRSVY 376
+KII+ + A+ E+R+L+ + ++D +Y + L+ F ++NH+CLV ++ ++Y
Sbjct: 187 IKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEMLSYNLY 246
Query: 377 DFMTNNGYARFPGSHVQAIGKQLVRSVCFLH--DLGIIHTDLKPENILICDETCVEQSLP 434
D + N + + + +Q+ ++ FL +L IIH DLKPENIL+C+
Sbjct: 247 DLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNP-------- 298
Query: 435 MEIIDSLTERRKLASGGKRKILINPEVKLIDFGSAVFYNEYHPPVVSTRHYRAPEIVLGL 494
KR +K++DFGS+ + + +R YR+PE++LG+
Sbjct: 299 -----------------KRSA-----IKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGM 336
Query: 495 GWSFPCDIWSIACVLVELVTGESLY 519
+ D+WS+ C+LVE+ TGE L+
Sbjct: 337 PYDLAIDMWSLGCILVEMHTGEPLF 361
>Hs18765752 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 754
Score = 134 bits (336), Expect = 6e-31
Identities = 76/265 (28%), Positives = 141/265 (52%), Gaps = 33/265 (12%)
Query: 257 SHQDKLRSMDRFKTDEEGHYVYQENDIFAKNRFQAMQLLGQGTFGKVVKCKDYLNDITVA 316
SH+ + + + D+ Y+ + + + +R++ L+G+G+FG+VVK D + VA
Sbjct: 119 SHKKERKVYNDGYDDDNYDYIVKNGEKWM-DRYEIDSLIGKGSFGQVVKAYDRVEQEWVA 177
Query: 317 VKIIRAVDRYRQAAKTELRVLQTIKENDRSGQYQCLLLREFFDYKNHICLVTDLYGRSVY 376
+KII+ + A+ E+R+L+ + ++D +Y + L+ F ++NH+CLV ++ ++Y
Sbjct: 178 IKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEMLSYNLY 237
Query: 377 DFMTNNGYARFPGSHVQAIGKQLVRSVCFLH--DLGIIHTDLKPENILICDETCVEQSLP 434
D + N + + + +Q+ ++ FL +L IIH DLKPENIL+C+
Sbjct: 238 DLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNP-------- 289
Query: 435 MEIIDSLTERRKLASGGKRKILINPEVKLIDFGSAVFYNEYHPPVVSTRHYRAPEIVLGL 494
KR +K++DFGS+ + + +R YR+PE++LG+
Sbjct: 290 -----------------KRSA-----IKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGM 327
Query: 495 GWSFPCDIWSIACVLVELVTGESLY 519
+ D+WS+ C+LVE+ TGE L+
Sbjct: 328 PYDLAIDMWSLGCILVEMHTGEPLF 352
>Hs18765750 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 584
Score = 134 bits (336), Expect = 6e-31
Identities = 76/265 (28%), Positives = 141/265 (52%), Gaps = 33/265 (12%)
Query: 257 SHQDKLRSMDRFKTDEEGHYVYQENDIFAKNRFQAMQLLGQGTFGKVVKCKDYLNDITVA 316
SH+ + + + D+ Y+ + + + +R++ L+G+G+FG+VVK D + VA
Sbjct: 128 SHKKERKVYNDGYDDDNYDYIVKNGEKWM-DRYEIDSLIGKGSFGQVVKAYDRVEQEWVA 186
Query: 317 VKIIRAVDRYRQAAKTELRVLQTIKENDRSGQYQCLLLREFFDYKNHICLVTDLYGRSVY 376
+KII+ + A+ E+R+L+ + ++D +Y + L+ F ++NH+CLV ++ ++Y
Sbjct: 187 IKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEMLSYNLY 246
Query: 377 DFMTNNGYARFPGSHVQAIGKQLVRSVCFLH--DLGIIHTDLKPENILICDETCVEQSLP 434
D + N + + + +Q+ ++ FL +L IIH DLKPENIL+C+
Sbjct: 247 DLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNP-------- 298
Query: 435 MEIIDSLTERRKLASGGKRKILINPEVKLIDFGSAVFYNEYHPPVVSTRHYRAPEIVLGL 494
KR +K++DFGS+ + + +R YR+PE++LG+
Sbjct: 299 -----------------KRSA-----IKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGM 336
Query: 495 GWSFPCDIWSIACVLVELVTGESLY 519
+ D+WS+ C+LVE+ TGE L+
Sbjct: 337 PYDLAIDMWSLGCILVEMHTGEPLF 361
>At1g13350 [A] KOG0670 U4/U6-associated splicing factor PRP4
Length = 888
Score = 132 bits (332), Expect = 2e-30
Identities = 119/420 (28%), Positives = 192/420 (45%), Gaps = 101/420 (24%)
Query: 271 DEEGHYVYQENDIFAKNRFQAMQLLGQGTFGKVVKCKDYLNDI----TVAVKIIRAVDRY 326
D EG+ + + D +R++ M G+G F VV+ KD ++ VA+KIIR +
Sbjct: 555 DAEGYQLGELLD----DRYEIMATHGKGVFSTVVRAKDTKAELGEPEEVAIKIIRNNETM 610
Query: 327 RQAAKTELRVLQTIKENDRSGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYAR 386
+A +TE+++L+ + +D + C+ F Y+NH+CLV + ++ + + Y R
Sbjct: 611 HKAGQTEIQILKKLAGSDPENKRHCVRFLSTFKYRNHLCLVFESLHLNLREIVKK--YGR 668
Query: 387 FPG---SHVQAIGKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTE 443
G S V+ QL S+ L + G++H D+KP+N+L+ +
Sbjct: 669 NIGIQLSGVRVYATQLFISLKHLKNCGVLHCDIKPDNMLVNE------------------ 710
Query: 444 RRKLASGGKRKILINPEVKLIDFGSAVFY--NEYHPPVVSTRHYRAPEIVLGLGWSFPCD 501
G+ + KL DFGSA+F NE P +VS R YRAPEI+LGL + P D
Sbjct: 711 -------GRNTL------KLCDFGSAMFAGTNEVTPYLVS-RFYRAPEIILGLPYDHPLD 756
Query: 502 IWSIACVLVELVTGESLYPIHENTEHMAMMQRINNEKFPKKMVEKMFFKVENKYGSIPTD 561
IWS+ C L EL +G+ ++P N E + + + FPKKM+ K F
Sbjct: 757 IWSVGCCLYELFSGKIMFPGSTNNEMLRLHMELKG-AFPKKMLRKGAF------------ 803
Query: 562 LQTSVVKYFDRQTGELRWPLRNSKGQVITKEKSWKRILATCDRLDVFISKKLQMDYGSWL 621
+ ++FD+ T+E S R T R+ V I K ++GS +
Sbjct: 804 ----IDQHFDKDL-----------CFYATEEDSVTR--KTTKRMMVNIKPK---EFGSVI 843
Query: 622 EIHWDMQLEDNWRLILSKNIDSRNIDKNVFMFWYYFVDLCRKMFEFDPTKRITAKEVIEH 681
+ + K+ DS+ + +F DL ++F DP KRIT + + H
Sbjct: 844 KQRY-------------KDEDSKLL--------VHFRDLLDRIFILDPQKRITVSQALAH 882
>At3g17750 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 1138
Score = 131 bits (329), Expect = 4e-30
Identities = 83/271 (30%), Positives = 134/271 (48%), Gaps = 40/271 (14%)
Query: 268 FKTDEEGHYVYQENDIFAKNRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYR 327
F+ D+ H V N + A R+ + LG F K ++ D I V VKII+ +
Sbjct: 809 FEEDKNFHVVL--NSVIA-GRYHVTEHLGSAAFSKAIQAHDLHTGIDVCVKIIKNNKDFF 865
Query: 328 QAAKTELRVLQTIKENDRSGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNN----G 383
+ E+++L+ + ++D + +Y L L ++F ++ H+ +V +L ++Y+F N G
Sbjct: 866 DQSLDEIKLLKYVNQHDPADKYHLLRLYDYFYFREHLLIVCELLKANLYEFQKFNRESGG 925
Query: 384 YARFPGSHVQAIGKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTE 443
F +Q+I Q + ++ FLH LG+IH DLKPENILI
Sbjct: 926 EVYFTMPRLQSITIQCLEALNFLHGLGLIHCDLKPENILI-------------------- 965
Query: 444 RRKLASGGKRKILINPEVKLIDFGSAVFYNEYHPPVVSTRHYRAPEIVLGLGWSFPCDIW 503
K E+K+ID GS+ F ++ V +R YRAPE++LGL + DIW
Sbjct: 966 ----------KSYSRCEIKVIDLGSSCFETDHLCSYVQSRSYRAPEVILGLPYDKKIDIW 1015
Query: 504 SIACVLVELVTGESLYPIHENTEHMAMMQRI 534
S+ C+L EL TG L+ +N ++ R+
Sbjct: 1016 SLGCILAELCTGNVLF---QNDSPATLLARV 1043
>At1g73460 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 1157
Score = 131 bits (329), Expect = 4e-30
Identities = 79/268 (29%), Positives = 134/268 (49%), Gaps = 38/268 (14%)
Query: 271 DEEGHYVYQENDIFAKNRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAA 330
+EE ++ N + A R+ + LG F K ++ D + V +KII+ + +
Sbjct: 829 EEEKNFNVVLNSVIA-GRYHVTEYLGSAAFSKAIQAHDLQTGMDVCIKIIKNNKDFFDQS 887
Query: 331 KTELRVLQTIKENDRSGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNN----GYAR 386
E+++L+ + ++D + +Y L L ++F Y+ H+ +V +L ++Y+F N G
Sbjct: 888 LDEIKLLKYVNKHDPADKYHLLRLYDYFYYREHLLIVCELLKANLYEFHKFNRESGGEVY 947
Query: 387 FPGSHVQAIGKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRK 446
F +Q+I Q + S+ FLH LG+IH DLKPENIL+
Sbjct: 948 FTMPRLQSITIQCLESLQFLHGLGLIHCDLKPENILV----------------------- 984
Query: 447 LASGGKRKILINPEVKLIDFGSAVFYNEYHPPVVSTRHYRAPEIVLGLGWSFPCDIWSIA 506
K E+K+ID GS+ F ++ V +R YRAPE++LGL + D+WS+
Sbjct: 985 -------KSYSRCEIKVIDLGSSCFETDHLCSYVQSRSYRAPEVILGLPYDKKIDVWSLG 1037
Query: 507 CVLVELVTGESLYPIHENTEHMAMMQRI 534
C+L EL TG L+ +N +++ R+
Sbjct: 1038 CILAELCTGNVLF---QNDSPASLLARV 1062
>At2g40120 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 570
Score = 129 bits (325), Expect = 1e-29
Identities = 105/404 (25%), Positives = 176/404 (42%), Gaps = 105/404 (25%)
Query: 288 RFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKENDRSG 347
R+ + +G F KVV+ +D N + V +KII+ + + E+++L+ + ++D +
Sbjct: 260 RYYITEYIGSAAFSKVVQAQDLHNGVDVCLKIIKNDKDFFDQSLDEIKLLKHVNKHDPAD 319
Query: 348 QYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNN----GYARFPGSHVQAIGKQLVRSV 403
++ L L ++F ++ H+ +V +L ++Y+F N G F S +Q I +Q + ++
Sbjct: 320 EHHILRLYDYFYHQEHLFIVCELLRANLYEFQKFNQESGGEPYFNLSRLQVITRQCLDAL 379
Query: 404 CFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKL 463
FLH LGIIH DLKPENILI K VK+
Sbjct: 380 VFLHGLGIIHCDLKPENILI------------------------------KSYKRCAVKI 409
Query: 464 IDFGSAVFYNEYHPPVVSTRHYRAPEIVLGLGWSFPCDIWSIACVLVELVTGESLYPIHE 523
ID GS+ F ++ V +R YRAPE++LGL + D+WS+ C+L EL +GE L+P
Sbjct: 410 IDLGSSCFRSDNLCLYVQSRSYRAPEVILGLPYDEKIDLWSLGCILAELCSGEVLFP--- 466
Query: 524 NTEHMAMMQRINNEKFP--KKMVEKMFFKVENKYGSIPTDLQTSVVKYFDRQTGELRWPL 581
N ++ RI P +M+EK + +KY + DL + + ++ E+ +
Sbjct: 467 NEAVAMILARIVAVLGPIETEMLEK--GQETHKYFTKEYDLY-----HLNEESNEIEY-- 517
Query: 582 RNSKGQVITKEKSWKRILATCDRLDVFISKKLQMDYGSWLEIHWDMQLEDNWRLILSKNI 641
+IT+E S + L D L
Sbjct: 518 ------IITEESSLEEQLQVSDEL------------------------------------ 535
Query: 642 DSRNIDKNVFMFWYYFVDLCRKMFEFDPTKRITAKEVIEHEWFN 685
F+D R + + +P +R TA E + H W +
Sbjct: 536 ---------------FLDFVRTLLDINPLRRPTALEALNHPWLS 564
>At1g73450 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 1155
Score = 129 bits (323), Expect = 2e-29
Identities = 98/428 (22%), Positives = 186/428 (42%), Gaps = 50/428 (11%)
Query: 106 VTGIAANNRNSKQNENGNGFDLVDLDDSAVEFVNS------VNYTSAKKVKKQRTVSLPQ 159
+ G N + + +N++G F + D F +S ++ S+K + ++ +
Sbjct: 634 IDGQNKNKQKASKNDSGGSFHVKIQTDGDFSFGSSQKDGQLMHAESSKSLWSGNRETVTR 693
Query: 160 LPHARLLYEPRNTDRRTQNDDELLHVSGTTTQTVDGNKLIKLPLIRSLSPVPVADFRLXX 219
+ LL TD + S ++ +V N + + S SP ++++
Sbjct: 694 DRNTELLSASTATDDMVATWRQKSSDSSSSRSSVKENNATSIKSVNS-SPSSLSNYARGE 752
Query: 220 XXXXXXXXXXXXFDISNSASKSPSRFTKILKKSPLLGSHQDKLRSMD--------RFKTD 271
+ ++ + + ++ + + +++ + D R +
Sbjct: 753 RKHAEKENDSSEREDGHATALDDEEAVAVQEQVRQIKAQEEEFETFDLKIVHRKNRTGFE 812
Query: 272 EEGHYVYQENDIFAKNRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAK 331
EE ++ N + A R+ + LG F K ++ D + V +KII+ + +
Sbjct: 813 EEKNFNVVLNSVIA-GRYHVTEYLGSAAFSKAIQAHDLQTGMDVCIKIIKNNKDFFDQSL 871
Query: 332 TELRVLQTIKENDRSGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNN----GYARF 387
E+++L+ + ++D + +Y L L ++F Y+ H+ +V +L ++Y+F N G F
Sbjct: 872 DEIKLLKYVNKHDPADKYHLLRLYDYFYYREHLLIVCELLKANLYEFHKFNRESGGEVYF 931
Query: 388 PGSHVQAIGKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKL 447
+Q+I Q + S+ FLH LG+IH DLKPENIL+
Sbjct: 932 TMPRLQSITIQCLESLQFLHGLGLIHCDLKPENILV------------------------ 967
Query: 448 ASGGKRKILINPEVKLIDFGSAVFYNEYHPPVVSTRHYRAPEIVLGLGWSFPCDIWSIAC 507
K E+K+ID GS+ F ++ V +R YRAPE++LGL + D+WS+ C
Sbjct: 968 ------KSYSRCEIKVIDLGSSCFETDHLCSYVQSRSYRAPEVILGLPYDKKIDVWSLGC 1021
Query: 508 VLVELVTG 515
+L EL TG
Sbjct: 1022 ILAELCTG 1029
>Hs17999535 [A] KOG0670 U4/U6-associated splicing factor PRP4
Length = 1007
Score = 128 bits (322), Expect = 3e-29
Identities = 90/287 (31%), Positives = 138/287 (47%), Gaps = 42/287 (14%)
Query: 270 TDEEGHYVYQENDIFAKNRFQAMQLLGQGTFGKVVKCKDYLN-DITVAVKIIRAVDRYRQ 328
TD EG+Y ++ K R+ GQG F VV+ +D + VAVKIIR + ++
Sbjct: 669 TDAEGYYRVNIGEVLDK-RYNVYGYTGQGVFSNVVRARDNARANQEVAVKIIRNNELMQK 727
Query: 329 AAKTELRVLQTIKENDRSGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFP 388
EL L+ + + D ++ CL L F +K H+CLV + ++ + + Y +
Sbjct: 728 TGLKELEFLKKLNDADPDDKFHCLRLFRHFYHKQHLCLVFEPLSMNLREVLKK--YGKDV 785
Query: 389 GSHVQAI---GKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERR 445
G H++A+ +QL ++ L I+H D+KP+NIL+ + +
Sbjct: 786 GLHIKAVRSYSQQLFLALKLLKRCNILHADIKPDNILVNESKTI---------------- 829
Query: 446 KLASGGKRKILINPEVKLIDFGSA--VFYNEYHPPVVSTRHYRAPEIVLGLGWSFPCDIW 503
+KL DFGSA V N+ P +VS R YRAPEI++G + + D+W
Sbjct: 830 ---------------LKLCDFGSASHVADNDITPYLVS-RFYRAPEIIIGKSYDYGIDMW 873
Query: 504 SIACVLVELVTGESLYPIHENTEHMAMMQRINNEKFPKKMVEKMFFK 550
S+ C L EL TG+ L+P N HM + K P KM+ K FK
Sbjct: 874 SVGCTLYELYTGKILFPGKTN-NHMLKLAMDLKGKMPNKMIRKGVFK 919
>CE06352 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 948
Score = 127 bits (320), Expect = 4e-29
Identities = 82/292 (28%), Positives = 144/292 (49%), Gaps = 40/292 (13%)
Query: 271 DEEGHYVYQENDIFAKNRFQAMQL-LGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQA 329
D+ Y+ + +IF K +G+G+FG+V K D LN VA+KII+ +
Sbjct: 375 DQNYDYILKNGEIFDKRYVILSDTPVGKGSFGQVTKAYDTLNKEEVAIKIIKNKKTFFDQ 434
Query: 330 AKTELRVLQTIKENDRSGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPG 389
A+ E+ +L+ +D+ +Y + L+ F ++ H+CLV +L ++YD + N +
Sbjct: 435 AQIEIHLLELTNAHDKDNKYNIVTLKGHFVHRAHLCLVFELLSYNLYDLLKNTSFRGVSL 494
Query: 390 SHVQAIGKQLVRSVCFLH--DLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKL 447
+ + +QL +++ FL +L IIH DLKPEN+L+ +
Sbjct: 495 NLARKFAQQLGKTLLFLSSPELSIIHCDLKPENVLLVN---------------------- 532
Query: 448 ASGGKRKILINPEVKLIDFGSAVFYNEYHPPVVSTRHYRAPEIVLGLGWSFPCDIWSIAC 507
KR ++++IDFGS+ + +R YR+PE++LG+ + D+WS+ C
Sbjct: 533 ---AKRS-----QIRVIDFGSSCQTGHRIYQYIQSRFYRSPEVLLGIAYDTKIDMWSLGC 584
Query: 508 VLVELVTGESLYPIHENTEHMAMMQRINNEKFPKKMVE------KMFFKVEN 553
+LVE+ TGE L+ + M + + PK+M++ K F K E+
Sbjct: 585 ILVEMHTGEPLFAGSSEVDQMMKIVEVLGMP-PKEMLDIGPKTHKYFDKTED 635
>At5g35980 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 787
Score = 126 bits (317), Expect = 1e-28
Identities = 80/273 (29%), Positives = 138/273 (50%), Gaps = 34/273 (12%)
Query: 285 AKNRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTI-KEN 343
++ R+ LLG GTFG+V KC + VAVK+I+ Y Q A E+ +L T+ K+
Sbjct: 118 SRQRYIVKDLLGHGTFGQVAKCWVPETNSFVAVKVIKNQLAYYQQALVEVSILTTLNKKY 177
Query: 344 DRSGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQLVRSV 403
D + + + ++F +++H+C+ +L ++Y+ + N + S V+ KQ++ +
Sbjct: 178 DPEDKNHIVRIYDYFLHQSHLCICFELLDMNLYELIKINQFRGLSLSIVKLFSKQILLGL 237
Query: 404 CFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINP-EVK 462
L D GIIH DLKPENIL+C + P E+K
Sbjct: 238 ALLKDAGIIHCDLKPENILLCAS------------------------------VKPTEIK 267
Query: 463 LIDFGSAVFYNEYHPPVVSTRHYRAPEIVLGLGWSFPCDIWSIACVLVELVTGESLYPIH 522
+IDFGSA ++ + +R+YR+PE++LG ++ D+WS C++ EL G L+P
Sbjct: 268 IIDFGSACMEDKTVYSYIQSRYYRSPEVLLGYQYTTAIDMWSFGCIVAELFLGLPLFPGG 327
Query: 523 ENTEHMAMMQRINNEKFPKKMVEKMFFKVENKY 555
+ + M I ++ P ++++ K NK+
Sbjct: 328 SEFDILRRMIEILGKQPPDYVLKEA--KNTNKF 358
>At3g25840 [A] KOG0670 U4/U6-associated splicing factor PRP4
Length = 932
Score = 125 bits (315), Expect = 2e-28
Identities = 91/286 (31%), Positives = 142/286 (48%), Gaps = 44/286 (15%)
Query: 271 DEEGHYVYQENDIFAKNRFQAMQLLGQGTFGKVVKCKDY----LNDITVAVKIIRAVDRY 326
D EG YQ ++ R++ + G+G F VV+ KD VA+KIIR +
Sbjct: 600 DAEG---YQFGELL-DGRYEVIATHGKGVFSTVVRAKDLKAGPAEPEEVAIKIIRNNETM 655
Query: 327 RQAAKTELRVLQTIKENDRSGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGY-A 385
+A K E+++L+ + DR + C+ F Y+NH+CLV + ++ + + G
Sbjct: 656 HKAGKIEVQILKKLAGADREDRRHCVRFLSSFKYRNHLCLVFESLHLNLREVLKKFGRNI 715
Query: 386 RFPGSHVQAIGKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERR 445
S V+A KQL ++ L + G++H D+KP+N+L+ +
Sbjct: 716 GLQLSAVRAYSKQLFIALKHLKNCGVLHCDIKPDNMLVNE-------------------- 755
Query: 446 KLASGGKRKILINPEVKLIDFGSAVFY--NEYHPPVVSTRHYRAPEIVLGLGWSFPCDIW 503
GK + KL DFG+A+F NE P +VS R YR+PEI+LGL + P DIW
Sbjct: 756 -----GKNVL------KLCDFGNAMFAGKNEVTPYLVS-RFYRSPEIILGLTYDHPLDIW 803
Query: 504 SIACVLVELVTGESLYPIHENTEHMAMMQRINNEKFPKKMVEKMFF 549
S+ C L EL +G+ L+P N + + + + FPKKM+ K F
Sbjct: 804 SVGCCLYELYSGKVLFPGATNNDMLRLHMELKG-PFPKKMLRKGAF 848
>SPAC1E11.03 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 534
Score = 124 bits (312), Expect = 4e-28
Identities = 76/249 (30%), Positives = 121/249 (48%), Gaps = 34/249 (13%)
Query: 276 YVYQENDIFAKN---RFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKT 332
YV ND+ + ++ + LG GTFG+V +C+D VA+K+I+ +
Sbjct: 114 YVLYVNDLLGTDEGRKYLILDTLGHGTFGQVARCQDLKTQQIVAIKVIKNKPAFYNQCVM 173
Query: 333 ELRVLQTIKEN-DRSGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSH 391
E+ +L+ + D + + L + F +KNH+CLV +L ++Y+ + N + S
Sbjct: 174 EVSILELLNNKYDPEDKRHLIRLYDQFMHKNHLCLVFELLSINLYELIKQNQFRGLHLSL 233
Query: 392 VQAIGKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGG 451
V++ QL+ L IIH DLKPENIL+ D
Sbjct: 234 VRSFATQLLSCTSLLKQARIIHCDLKPENILLQD-------------------------- 267
Query: 452 KRKILINPEVKLIDFGSAVFYNEYHPPVVSTRHYRAPEIVLGLGWSFPCDIWSIACVLVE 511
L +P VK+IDFGSA + + +R YR+PE++LGL ++ D+WS+ C+L E
Sbjct: 268 ----LSSPIVKVIDFGSACHERQTVYTYIQSRFYRSPEVILGLHYNCGIDMWSLGCILAE 323
Query: 512 LVTGESLYP 520
L G L+P
Sbjct: 324 LFLGLPLFP 332
>At4g35500 [T] KOG1290 Serine/threonine protein kinase
Length = 438
Score = 122 bits (306), Expect = 2e-27
Identities = 91/322 (28%), Positives = 150/322 (46%), Gaps = 53/322 (16%)
Query: 274 GHYVYQENDIFAKNRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTE 333
G++ + D F+ R+ A + LG G F V D L VA+KI ++ ++ QAA E
Sbjct: 23 GYHAVRIGDPFSGGRYIAQRKLGWGQFSTVWLAYDTLTSTYVALKIQKSAQQFAQAALHE 82
Query: 334 LRVLQTIKENDRSGQYQCLLLREFFDYK----NHICLVTDLYGRSVYDFMTNNGYARFPG 389
+ L + D + L + F + H+C+V + G S+ + N Y
Sbjct: 83 IEFLSAAADGDLDKTKCVVRLIDHFKHSGPNGQHLCMVLEFLGDSLLRLIRYNQYKGLKL 142
Query: 390 SHVQAIGKQLVRSVCFLH-DLGIIHTDLKPENILICDE---------------------- 426
+ V+ I + ++ + +LH +LG+IH+DLKPENIL+C
Sbjct: 143 NKVREICRCILTGLDYLHRELGMIHSDLKPENILLCSTIDPAKDPVRSGLTPLLEKPEGN 202
Query: 427 --------TCVEQSL---PMEIIDSLTERR------KLASGGKRKIL--INPEVKLIDFG 467
+E+ L + ++ERR + AS K L I+ K++DFG
Sbjct: 203 ANGGASTMNLIEKKLKRRAKRAVAKISERRVSMVTGEEASSKTEKSLDGIDMRCKVVDFG 262
Query: 468 SAVFYNEYHPPVVSTRHYRAPEIVLGLGWSFPCDIWSIACVLVELVTGESLYP------I 521
+A + ++ + TR YRAPE++L G+SF D+WS C ELVTG+ L+
Sbjct: 263 NACWADKQFAEEIQTRQYRAPEVILKSGYSFSVDMWSFGCTAFELVTGDMLFAPKDGNGY 322
Query: 522 HENTEHMAMMQRINNEKFPKKM 543
E+ +H+A+M + K P+K+
Sbjct: 323 GEDEDHLALMMELLG-KMPRKI 343
>At2g17530 [T] KOG1290 Serine/threonine protein kinase
Length = 440
Score = 121 bits (303), Expect = 4e-27
Identities = 96/341 (28%), Positives = 160/341 (46%), Gaps = 59/341 (17%)
Query: 256 GSHQDKLRSMDRFKTDEEGHYVYQENDIFAKNRFQAMQLLGQGTFGKVVKCKDYLNDITV 315
GS +D D ++ + G++ + D FA R+ A + LG G F V D V
Sbjct: 8 GSEEDD-EGFDAYR--KGGYHAVRIGDQFAGGRYIAQRKLGWGQFSTVWLAYDTRTSNYV 64
Query: 316 AVKIIRAVDRYRQAAKTELRVLQTIKENDRSGQYQCLLLREFFDYKN------HICLVTD 369
A+KI ++ ++ QAA E+ +LQ + D +C ++R D+K+ H+C+V +
Sbjct: 65 ALKIQKSALQFAQAALHEIELLQAAADGDPENT-KC-VIRLIDDFKHAGPNGQHLCMVLE 122
Query: 370 LYGRSVYDFMTNNGYARFPGSHVQAIGKQLVRSVCFLH-DLGIIHTDLKPENILICD--- 425
G S+ + N Y S V+ I K ++ + +LH +LG+IH+DLKPENIL+C
Sbjct: 123 FLGDSLLRLIKYNRYKGMELSKVREICKCILTGLDYLHRELGMIHSDLKPENILLCSTID 182
Query: 426 -----------------ETCVEQSLPMEIIDSLTERRKLASGGK---RKIL--------- 456
E + M +I+ +RR + K R++
Sbjct: 183 PAKDPIRSGLTPILEKPEGNQNGTSTMNLIEKKLKRRAKKAAAKISGRRVSIVGLSETPK 242
Query: 457 --------INPEVKLIDFGSAVFYNEYHPPVVSTRHYRAPEIVLGLGWSFPCDIWSIACV 508
I+ K++DFG+ + + + TR YRAPE++L G+S+ D+WS AC
Sbjct: 243 KNKRNLDGIDMRCKVVDFGNGCWADNKFAEEIQTRQYRAPEVILQSGYSYSVDMWSFACT 302
Query: 509 LVELVTGESLYP------IHENTEHMAMMQRINNEKFPKKM 543
EL TG+ L+ E+ +H+A+M + K P+K+
Sbjct: 303 AFELATGDMLFAPKEGNGYGEDEDHLALMMELLG-KMPRKI 342
>7291932 [A] KOG0670 U4/U6-associated splicing factor PRP4
Length = 907
Score = 121 bits (303), Expect = 4e-27
Identities = 110/458 (24%), Positives = 191/458 (41%), Gaps = 55/458 (12%)
Query: 103 GSFVTGIAANNRNSKQNENGNGFDLVDLDDSAVEFVNSVNYTSAKKVKKQRTVSLPQLPH 162
GS G ++ S E D+++ DD + + +KK T PH
Sbjct: 413 GSLSEGQNKLDKESSDEEVNVNIDILEEDDEE-RIIELRRKKREELLKKLGTGQESPAPH 471
Query: 163 ARLLYEPRNTDRRTQNDDELLHVSGTTTQTVDGNKLI-KLPLIRSLSPVPVADFRLXXXX 221
+ YE R+T + + + L T N LI ++P R +
Sbjct: 472 NSVSYESRSTSQGSSQRERPLRTPSPTMPCP--NPLISEIPKDREDMDNSTSQKTCSAKE 529
Query: 222 XXXXXXXXXXFDISNSASKSPSRFTKILKKSPLLGSHQDKLRSMDRFKTDEEGHYVYQEN 281
D+ ++ SP+ + HQ + ++ D EG+Y +
Sbjct: 530 KRNEWDMFADQDVDSNFD-SPNTIVQ--------NKHQHENPALTDNWDDAEGYYRVRIG 580
Query: 282 DIFAKNRFQAMQLLGQGTFGKVVKCKDYLN-DITVAVKIIRAVDRYRQAAKTELRVLQTI 340
++ NR+ GQG F VV+ +D VA+KIIR + + EL +L+ +
Sbjct: 581 EVL-DNRYLVNGYTGQGVFSNVVRGRDQARGQANVAIKIIRNNEIMHKTGLRELEILKKL 639
Query: 341 KENDRSGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQAI---GK 397
+ D ++ CL L F +K H+C+V + ++ + + Y + G H++A+ +
Sbjct: 640 NDADPEDRFHCLRLYRHFFHKQHLCMVFEPLAMNLREVLKK--YGKNVGLHIKAVRSYTQ 697
Query: 398 QLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILI 457
QL ++ L GI+H D+KP+NIL+ + +
Sbjct: 698 QLFLALKLLKKTGILHADIKPDNILVNENNLI---------------------------- 729
Query: 458 NPEVKLIDFG--SAVFYNEYHPPVVSTRHYRAPEIVLGLGWSFPCDIWSIACVLVELVTG 515
+KL DFG SA+ NE P +VS R YR+PEI+LG+ + + D WS C + EL TG
Sbjct: 730 ---LKLCDFGSASAISDNEITPYLVS-RFYRSPEIILGIPYDYGIDTWSAGCTIYELYTG 785
Query: 516 ESLYPIHENTEHMAMMQRINNEKFPKKMVEKMFFKVEN 553
+ L+ N + + + K P +++ K F+ ++
Sbjct: 786 KILFSGKSNNQMLKFFMDVKG-KIPNRIIRKGQFREQH 822
>Hs21389587 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 541
Score = 120 bits (301), Expect = 7e-27
Identities = 83/257 (32%), Positives = 129/257 (49%), Gaps = 36/257 (14%)
Query: 289 FQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYR-QAAKTELRVLQTIKENDRSG 347
+ +++LG+GTFG+V K VA+KI++ D YR + K EL++L ++ D
Sbjct: 11 YDIIEVLGKGTFGEVAKGWRRSTGEMVAIKILKN-DAYRNRIIKNELKLLHCMRGLDPEE 69
Query: 348 QYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQLVRSVCFLH 407
+ L EFF LV +L +++++F N +A P H++ + Q++ ++ L
Sbjct: 70 AHVIRFL-EFFHDALKFYLVFELLEQNLFEFQKENNFAPLPARHIRTVTLQVLTALARLK 128
Query: 408 DLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKLIDFG 467
+L IIH DLKPENI++ D+T P VK+IDFG
Sbjct: 129 ELAIIHADLKPENIMLVDQT----RCPF------------------------RVKVIDFG 160
Query: 468 SAVFYNEYH---PPVVSTRHYRAPEIVLGLGWSFPCDIWSIACVLVELVTGESLYPIHEN 524
SA ++E P + +R YRAPEI+LGL + D+WS+ CV+ EL G LYP N
Sbjct: 161 SASIFSEVRYVKEPYIQSRFYRAPEILLGLPFCEKVDVWSLGCVMAELHLGWPLYP--GN 218
Query: 525 TEHMAMMQRINNEKFPK 541
E+ + + PK
Sbjct: 219 NEYDQVRYICETQGLPK 235
>SPCC777.14 [A] KOG0670 U4/U6-associated splicing factor PRP4
Length = 477
Score = 117 bits (292), Expect = 8e-26
Identities = 88/287 (30%), Positives = 138/287 (47%), Gaps = 47/287 (16%)
Query: 271 DEEGHY---VYQENDIFAKNRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYR 327
D EG+Y + +E D +R+ LG+G F VV D + T A+KIIR +
Sbjct: 142 DIEGYYKVVLMEELD----SRYIVQSNLGKGMFSTVVSALDRNRNQTFAIKIIRNNEVMY 197
Query: 328 QAAKTELRVLQTIKENDRSGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARF 387
+ E+ +L+ ++ DR G+ + F +KNH+C+V ++ ++ D + G R
Sbjct: 198 KEGLKEVSILERLQAADREGKQHIIHYERHFMHKNHLCMVFEMLSLNLRDILKKFG--RN 255
Query: 388 PGSHVQAI---GKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTER 444
G ++A+ Q+ ++ L +IH+D+KP+N+L+ +
Sbjct: 256 VGLSIKAVRLYAYQMFMALDLLKQCNVIHSDIKPDNMLVNE------------------- 296
Query: 445 RKLASGGKRKILINPEVKLIDFGSA--VFYNEYHPPVVSTRHYRAPEIVLGLGWSFPCDI 502
KR IL K+ D GSA NE P +VS R YRAPEI+LG +S P D
Sbjct: 297 -------KRNIL-----KICDLGSASDASENEITPYLVS-RFYRAPEIILGFPYSCPIDT 343
Query: 503 WSIACVLVELVTGESLYPIHENTEHMAMMQRINNEKFPKKMVEKMFF 549
WS+ C L EL TG+ L+P N + + M KF KM+++ F
Sbjct: 344 WSVGCSLYELYTGQILFPGRTNNQMLRYMMECKG-KFSHKMLKRSQF 389
>Hs20468251 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 370
Score = 103 bits (256), Expect = 1e-21
Identities = 54/169 (31%), Positives = 98/169 (57%), Gaps = 5/169 (2%)
Query: 273 EGHYVYQENDIFAK--NRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAA 330
EG Y +++I N ++ ++ LG+GTFG+V KC VA+KI++ Y +
Sbjct: 172 EGDYQLVQHEILCSMTNSYEVLEFLGRGTFGQVAKCWKRSTKEIVAIKILKNHPSYARQG 231
Query: 331 KTELRVLQTIKENDRSGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGS 390
+ E+ +L + ++ + +Y + E F +KNH CLV ++ +++YDF+ N ++ P
Sbjct: 232 QIEVSILSRLS-SENADEYNFVRSYECFQHKNHTCLVFEMLEQNLYDFLKQNKFSPLPLK 290
Query: 391 HVQAIGKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIID 439
+++ I +Q+ ++ L LG+IH DLKPENI++ D V Q +++ID
Sbjct: 291 YIRPILQQVATALMKLKSLGLIHADLKPENIMLVDP--VRQPYRVKVID 337
>Hs4503069 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 99.0 bits (245), Expect = 2e-20
Identities = 75/256 (29%), Positives = 119/256 (46%), Gaps = 52/256 (20%)
Query: 288 RFQAMQLLGQGTFGKVVKCKDYLNDITVAVK--------IIRAVDRYRQAAKTELRVLQT 339
R+Q + +G G +G V D + VAVK II A YR ELR+L+
Sbjct: 23 RYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYR-----ELRLLKH 77
Query: 340 IKENDRSGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQL 399
+K + G + N + LVT L G + + + + HVQ + Q+
Sbjct: 78 MKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ---KLTDDHVQFLIYQI 134
Query: 400 VRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINP 459
+R + ++H IIH DLKP N+ + +E C
Sbjct: 135 LRGLKYIHSADIIHRDLKPSNLAV-NEDC------------------------------- 162
Query: 460 EVKLIDFGSAVFYNEYHPPVVSTRHYRAPEIVLG-LGWSFPCDIWSIACVLVELVTGESL 518
E+K++DFG A ++ V+TR YRAPEI+L + ++ DIWS+ C++ EL+TG +L
Sbjct: 163 ELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTL 222
Query: 519 YPIHENTEHMAMMQRI 534
+P T+H+ +Q+I
Sbjct: 223 FP---GTDHINQLQQI 235
>Hs20986516 [T] KOG0660 Mitogen-activated protein kinase
Length = 307
Score = 97.1 bits (240), Expect = 8e-20
Identities = 72/256 (28%), Positives = 119/256 (46%), Gaps = 49/256 (19%)
Query: 288 RFQAMQLLGQGTFGKVVKCKDYLNDITVAVK--------IIRAVDRYRQAAKTELRVLQT 339
R+Q + +G G +G V D + VAVK II A YR ELR+L+
Sbjct: 23 RYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYR-----ELRLLKH 77
Query: 340 IKENDRSGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQL 399
+K + G + N + LVT L G + + + + HVQ + Q+
Sbjct: 78 MKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ---KLTDDHVQFLIYQI 134
Query: 400 VRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINP 459
+R + ++H IIH DLKP N+ + +E C
Sbjct: 135 LRGLKYIHSADIIHRDLKPSNLAV-NEDC------------------------------- 162
Query: 460 EVKLIDFGSAVFYNEYHPPVVSTRHYRAPEIVLG-LGWSFPCDIWSIACVLVELVTGESL 518
E+K++DFG A ++ V+TR YRAPEI+L + ++ DIWS+ C++ EL+TG +L
Sbjct: 163 ELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTL 222
Query: 519 YPIHENTEHMAMMQRI 534
+P ++ + + ++ R+
Sbjct: 223 FPGTDHIDQLKLILRL 238
>Hs20986514 [T] KOG0660 Mitogen-activated protein kinase
Length = 297
Score = 97.1 bits (240), Expect = 8e-20
Identities = 72/256 (28%), Positives = 119/256 (46%), Gaps = 49/256 (19%)
Query: 288 RFQAMQLLGQGTFGKVVKCKDYLNDITVAVK--------IIRAVDRYRQAAKTELRVLQT 339
R+Q + +G G +G V D + VAVK II A YR ELR+L+
Sbjct: 23 RYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYR-----ELRLLKH 77
Query: 340 IKENDRSGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQL 399
+K + G + N + LVT L G + + + + HVQ + Q+
Sbjct: 78 MKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ---KLTDDHVQFLIYQI 134
Query: 400 VRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINP 459
+R + ++H IIH DLKP N+ + +E C
Sbjct: 135 LRGLKYIHSADIIHRDLKPSNLAV-NEDC------------------------------- 162
Query: 460 EVKLIDFGSAVFYNEYHPPVVSTRHYRAPEIVLG-LGWSFPCDIWSIACVLVELVTGESL 518
E+K++DFG A ++ V+TR YRAPEI+L + ++ DIWS+ C++ EL+TG +L
Sbjct: 163 ELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTL 222
Query: 519 YPIHENTEHMAMMQRI 534
+P ++ + + ++ R+
Sbjct: 223 FPGTDHIDQLKLILRL 238
>Hs20986512 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 97.1 bits (240), Expect = 8e-20
Identities = 72/256 (28%), Positives = 119/256 (46%), Gaps = 49/256 (19%)
Query: 288 RFQAMQLLGQGTFGKVVKCKDYLNDITVAVK--------IIRAVDRYRQAAKTELRVLQT 339
R+Q + +G G +G V D + VAVK II A YR ELR+L+
Sbjct: 23 RYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYR-----ELRLLKH 77
Query: 340 IKENDRSGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQL 399
+K + G + N + LVT L G + + + + HVQ + Q+
Sbjct: 78 MKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ---KLTDDHVQFLIYQI 134
Query: 400 VRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINP 459
+R + ++H IIH DLKP N+ + +E C
Sbjct: 135 LRGLKYIHSADIIHRDLKPSNLAV-NEDC------------------------------- 162
Query: 460 EVKLIDFGSAVFYNEYHPPVVSTRHYRAPEIVLG-LGWSFPCDIWSIACVLVELVTGESL 518
E+K++DFG A ++ V+TR YRAPEI+L + ++ DIWS+ C++ EL+TG +L
Sbjct: 163 ELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTL 222
Query: 519 YPIHENTEHMAMMQRI 534
+P ++ + + ++ R+
Sbjct: 223 FPGTDHIDQLKLILRL 238
>Hs4507281 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 1030
Score = 94.0 bits (232), Expect = 7e-19
Identities = 69/261 (26%), Positives = 123/261 (46%), Gaps = 58/261 (22%)
Query: 287 NRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKT---ELRVLQTIKEN 343
N+F+ + ++G+G +G V+KC+ VA+K + + + +T EL++L+T+K
Sbjct: 11 NKFEILGVVGEGAYGVVLKCRHKETHEIVAIKKFKDSEENEEVKETTLRELKMLRTLK-- 68
Query: 344 DRSGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTN--NGYARFPGSHVQAIGKQLVR 401
Q + L+E F + + LV + +++ + + NG P V++ QL++
Sbjct: 69 ----QENIVELKEAFRRRGKLYLVFEYVEKNMLELLEEMPNG---VPPEKVKSYIYQLIK 121
Query: 402 SVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEV 461
++ + H I+H D+KPEN+LI N +
Sbjct: 122 AIHWCHKNDIVHRDIKPENLLISH--------------------------------NDVL 149
Query: 462 KLIDFGSA--------VFYNEYHPPVVSTRHYRAPEIVLGLGWSFPCDIWSIACVLVELV 513
KL DFG A Y EY V+TR YR+PE++LG + D+WS+ C+L EL
Sbjct: 150 KLCDFGFARNLSEGNNANYTEY----VATRWYRSPELLLGAPYGKSVDMWSVGCILGELS 205
Query: 514 TGESLYPIHENTEHMAMMQRI 534
G+ L+P + + +Q++
Sbjct: 206 DGQPLFPGESEIDQLFTIQKV 226
>SPAC24B11.06c [T] KOG0660 Mitogen-activated protein kinase
Length = 349
Score = 93.6 bits (231), Expect = 9e-19
Identities = 71/250 (28%), Positives = 112/250 (44%), Gaps = 42/250 (16%)
Query: 288 RFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKE--NDR 345
R+ +Q +G G FG V KD L + VAVK I AK R L+ +K ++
Sbjct: 19 RYSDLQPIGMGAFGLVCSAKDQLTGMNVAVKKIMKPFSTPVLAKRTYRELKLLKHLRHEN 78
Query: 346 SGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQLVRSVCF 405
+ + F D I VT+L G ++ +T+ +Q Q++R + F
Sbjct: 79 IISLSDIFISPFED----IYFVTELLGTDLHRLLTSRPLET---QFIQYFLYQILRGLKF 131
Query: 406 LHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKLID 465
+H G+IH DLKP NILI +E C ++K+ D
Sbjct: 132 VHSAGVIHRDLKPSNILI-NENC-------------------------------DLKICD 159
Query: 466 FGSAVFYNEYHPPVVSTRHYRAPEIVL-GLGWSFPCDIWSIACVLVELVTGESLYPIHEN 524
FG A + VSTR+YRAPEI+L ++ DIWS C+ E++ G+ L+P ++
Sbjct: 160 FGLARIQDPQMTGYVSTRYYRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGRDH 219
Query: 525 TEHMAMMQRI 534
+++ +
Sbjct: 220 VNQFSIITEL 229
>CE20258 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 353
Score = 93.2 bits (230), Expect = 1e-18
Identities = 73/261 (27%), Positives = 123/261 (46%), Gaps = 45/261 (17%)
Query: 287 NRFQAMQLLGQGTFGKVVKCKDYLNDITVAV-KIIRAVD--RYRQAAKTELRVLQTIKEN 343
+++ + LG+G++G V KCK+ VA+ K + D ++ A E+R+L+ +K
Sbjct: 2 DKYDRLSKLGEGSYGVVYKCKNRDTGQIVAIKKFVETEDDPHIKKIALREIRMLKQLKHQ 61
Query: 344 DRSGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQLVRSV 403
+ G L E F + LV +L R+V + N + ++ I QL+ ++
Sbjct: 62 NLVG------LIEVFKRNRKLHLVFELCDRTVLHELEKNPHG-VNDELIKKIIYQLLEAL 114
Query: 404 CFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKL 463
F H IH D+KPENI + N +VKL
Sbjct: 115 KFCHSHKCIHRDVKPENIFLTR--------------------------------NDQVKL 142
Query: 464 IDFGSAVFYN--EYHPPVVSTRHYRAPEIVLG-LGWSFPCDIWSIACVLVELVTGESLYP 520
DFG A N E + V+TR YR+PE+++G + + P DIW++ CV EL+TGE+L+P
Sbjct: 143 GDFGFARIINTTEMYTDYVATRWYRSPELLVGDVQYGPPVDIWAVGCVYAELLTGEALWP 202
Query: 521 IHENTEHMAMMQRINNEKFPK 541
+ + + +++ E P+
Sbjct: 203 GRSDIDQLYHIRKTLGEFLPR 223
>7297009 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 392
Score = 92.8 bits (229), Expect = 2e-18
Identities = 73/261 (27%), Positives = 123/261 (46%), Gaps = 45/261 (17%)
Query: 287 NRFQAMQLLGQGTFGKVVKCKDYLNDITVAVK-IIRAVD--RYRQAAKTELRVLQTIKEN 343
+R++ + LG+G++G V KC+D VAVK + + D R+ A E+R+L+ +K
Sbjct: 2 DRYEKLSRLGEGSYGVVYKCRDRETGALVAVKRFVESEDDPAIRKIALREIRLLKNLKHP 61
Query: 344 DRSGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQLVRSV 403
+ + L E F K + LV + +V + + P + I Q + V
Sbjct: 62 N------LVSLLEVFRRKRRLHLVFEFCELTVLHELERHPQG-CPEHLTKQICYQTLLGV 114
Query: 404 CFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKL 463
+ H G +H D+KPENIL+ A G +VKL
Sbjct: 115 AYCHKQGCLHRDIKPENILLT-----------------------AQG---------QVKL 142
Query: 464 IDFGSAVFYN--EYHPPVVSTRHYRAPEIVLG-LGWSFPCDIWSIACVLVELVTGESLYP 520
DFG A + E + V+TR YRAPE+++G + P D+W+I C+ ELV GE+L+P
Sbjct: 143 CDFGFARMLSPGENYTDYVATRWYRAPELLVGDTQYGTPVDVWAIGCLFAELVRGEALWP 202
Query: 521 IHENTEHMAMMQRINNEKFPK 541
+ + + ++++ + P+
Sbjct: 203 GRSDVDQLYLIRKTLGDLLPR 223
>SPBC8D2.01 [G] KOG0658 Glycogen synthase kinase-3
Length = 381
Score = 91.7 bits (226), Expect = 4e-18
Identities = 71/259 (27%), Positives = 118/259 (45%), Gaps = 55/259 (21%)
Query: 289 FQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKENDRSGQ 348
++ ++LG G+FG V++ K +AVK + RY+ EL++++ I +
Sbjct: 25 YEPCRVLGSGSFGVVIQAKLVGTPGFIAVKRVLQDKRYKNR---ELQIMRAISHPN---- 77
Query: 349 YQCLLLREFFDYKN------HICLVTDLYGRSVYDFMTNNGYAR----FPGSHVQAIGKQ 398
+ L FF N H+CL+ + +V+D M Y R P ++ Q
Sbjct: 78 --IIKLIAFFHTHNPSKDETHLCLLLEYMPETVFDDM--RWYTRRRKSIPNLSIKLYAFQ 133
Query: 399 LVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILIN 458
L R++ +LH G+ H D+KP+N+L+ +T +
Sbjct: 134 LFRALAYLHSTGVCHRDIKPQNLLVDYKTGI----------------------------- 164
Query: 459 PEVKLIDFGSAVFYNEYHPPV--VSTRHYRAPEIVLG-LGWSFPCDIWSIACVLVELVTG 515
+KL DFGSA P V + +R+YRAPE+V G ++ D+WS ACV+ EL G
Sbjct: 165 --LKLCDFGSAKVLVPSEPNVSYICSRYYRAPELVFGATHYTTKIDVWSAACVIAELFIG 222
Query: 516 ESLYPIHENTEHMAMMQRI 534
L+P + E + + R+
Sbjct: 223 RPLFPGDSSVEQLVEIIRV 241
>Hs20128774 [T] KOG0660 Mitogen-activated protein kinase
Length = 364
Score = 91.3 bits (225), Expect = 5e-18
Identities = 71/251 (28%), Positives = 119/251 (47%), Gaps = 42/251 (16%)
Query: 288 RFQAMQLLGQGTFGKVVKCKDYLNDITVAVK-IIRAVDRYRQAAKT--ELRVLQTIKEND 344
R Q ++ +G G +G V D VAVK + R A +T ELR+L+ +K +
Sbjct: 23 RLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQSLIHARRTYRELRLLKHLKHEN 82
Query: 345 RSGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQLVRSVC 404
G + + + LVT L G + + + + HVQ + QL+R +
Sbjct: 83 VIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQALS---DEHVQFLVYQLLRGLK 139
Query: 405 FLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKLI 464
++H GIIH DLKP N+ + +E C E++++
Sbjct: 140 YIHSAGIIHRDLKPSNVAV-NEDC-------------------------------ELRIL 167
Query: 465 DFGSAVFYNEYHPPVVSTRHYRAPEIVLG-LGWSFPCDIWSIACVLVELVTGESLYPIHE 523
DFG A +E V+TR YRAPEI+L + ++ DIWS+ C++ EL+ G++L+P
Sbjct: 168 DFGLARQADEEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFP--- 224
Query: 524 NTEHMAMMQRI 534
++++ ++RI
Sbjct: 225 GSDYIDQLKRI 235
>SPBC530.14c [T] KOG1290 Serine/threonine protein kinase
Length = 544
Score = 90.9 bits (224), Expect = 6e-18
Identities = 55/175 (31%), Positives = 95/175 (53%), Gaps = 15/175 (8%)
Query: 265 MDRFKTDEE--------GHYVYQENDIFAKNRFQAMQLLGQGTFGKVVKCKDYLNDITVA 316
+++ KT EE G++ + F R+ + LG G F V D VA
Sbjct: 49 VEKVKTHEENAEDYHYGGYHPVYIGEEFHHRRYVVERKLGWGHFSTVWLAYDRAAKRRVA 108
Query: 317 VKIIRAVDRYRQAAKTELRVLQTIKENDRS--GQYQCLLLREFFDYKN----HICLVTDL 370
+K++R+ + YR+ + E+R+LQ I+E D G+ + L ++F ++ H+C+V ++
Sbjct: 109 LKVVRSAEHYRETSIDEIRILQKIREGDEKHLGKKHIISLLDYFVHRGPNGAHVCMVFEV 168
Query: 371 YGRSVYDFMTNNGYARFPGSHVQAIGKQLVRSVCFLH-DLGIIHTDLKPENILIC 424
G ++ + + G+ P V+ I QL+ ++ +LH + GIIHTDLKPEN+LIC
Sbjct: 169 LGENLLSLIQSYGHRGVPVGIVKQIAYQLLIALDYLHRECGIIHTDLKPENVLIC 223
Score = 61.2 bits (147), Expect = 5e-09
Identities = 32/89 (35%), Positives = 53/89 (58%), Gaps = 7/89 (7%)
Query: 461 VKLIDFGSAVFYNEYHPPVVSTRHYRAPEIVLGLGWSFPCDIWSIACVLVELVTGESLY- 519
VK+ D G+A + ++ V TR YR+PE++LG W D WS AC++ EL+TG+ L+
Sbjct: 356 VKIADLGNACWTRKHFTNDVQTRQYRSPEVILGCRWGASADCWSFACIIFELLTGDYLFD 415
Query: 520 PIHENT-----EHMAMMQRINNEKFPKKM 543
P + N+ +H+A + + +PK+M
Sbjct: 416 PRNGNSYSKEDDHIAQIIEL-LVNYPKQM 443
>SPBC11B10.09 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 297
Score = 90.9 bits (224), Expect = 6e-18
Identities = 72/241 (29%), Positives = 107/241 (43%), Gaps = 42/241 (17%)
Query: 289 FQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKE-NDRSG 347
+Q ++ +G+GT+G V K + L+ VA+K IR D T +R + +KE ND +
Sbjct: 4 YQKVEKIGEGTYGVVYKARHKLSGRIVAMKKIRLEDESEGVPSTAIREISLLKEVNDENN 63
Query: 348 QYQCLLLREFFDYKNHICLV---TDLYGRSVYDFMTNNGYARFPGSHVQAIGKQLVRSVC 404
+ C+ L + ++ + LV D+ + D ++ G VQ QLV V
Sbjct: 64 RSNCVRLLDILHAESKLYLVFEFLDMDLKKYMDRISETGATSLDPRLVQKFTYQLVNGVN 123
Query: 405 FLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKLI 464
F H IIH DLKP+N+LI E +KL
Sbjct: 124 FCHSRRIIHRDLKPQNLLIDKE--------------------------------GNLKLA 151
Query: 465 DFGSA----VFYNEYHPPVVSTRHYRAPEIVLG-LGWSFPCDIWSIACVLVELVTGESLY 519
DFG A V Y +V T YRAPE++LG +S DIWS+ C+ E++ L+
Sbjct: 152 DFGLARSFGVPLRNYTHEIV-TLWYRAPEVLLGSRHYSTGVDIWSVGCIFAEMIRRSPLF 210
Query: 520 P 520
P
Sbjct: 211 P 211
>7298087 [T] KOG0660 Mitogen-activated protein kinase
Length = 365
Score = 89.0 bits (219), Expect = 2e-17
Identities = 68/253 (26%), Positives = 113/253 (43%), Gaps = 45/253 (17%)
Query: 289 FQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKENDRSGQ 348
+Q +Q +GQG +G+V K VA+K + + AK R L+ +K D
Sbjct: 24 YQNLQPVGQGAYGQVCKAVVRGTSTKVAIKKLARPFQSAVHAKRTYRELRLLKHMDHENV 83
Query: 349 YQCLLL------REFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQLVRS 402
L + + D + +VT L + + + + HVQ + Q++R
Sbjct: 84 IGLLDVFHPGQPADSLDQFQQVYMVTHLMDADLNNIIRTQ---KLSDDHVQFLVYQILRG 140
Query: 403 VCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVK 462
+ ++H G+IH DLKP NI + +E C E++
Sbjct: 141 LKYIHSAGVIHRDLKPSNIAV-NEDC-------------------------------ELR 168
Query: 463 LIDFGSAVFYNEYHPPVVSTRHYRAPEIVLG-LGWSFPCDIWSIACVLVELVTGESLYPI 521
++DFG A V+TR YRAPEI+L + ++ DIWS+ C++ EL+TG +L+P
Sbjct: 169 ILDFGLARPAESEMTGYVATRWYRAPEIMLNWMHYNQTADIWSVGCIMAELLTGRTLFP- 227
Query: 522 HENTEHMAMMQRI 534
T+H+ + I
Sbjct: 228 --GTDHIHQLNLI 238
>CE04173 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 531
Score = 88.2 bits (217), Expect = 4e-17
Identities = 68/267 (25%), Positives = 116/267 (42%), Gaps = 36/267 (13%)
Query: 272 EEGHYVYQENDIFAKNRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAK 331
E G + D R+ +++GQG +G V + D VA IR V +
Sbjct: 178 EMGSIYKMKKDEHIGYRYTIDKVIGQGCYGVVGEATDGKTKQKVA---IRMVSKLAPRIY 234
Query: 332 TELRVLQTIKENDRSGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSH 391
E ++ I D + C+ + ++ ++ +VTDL+ SV ++ + +
Sbjct: 235 RETEMIMYISSIDPDHTFDCVRMLDYNVFRGFHYVVTDLFDTSVKKYIKEHHPNGIALEN 294
Query: 392 VQAIGKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGG 451
V A+G+++++ + FLH+ I+H DLKPENI++
Sbjct: 295 VAAMGRKILKGLVFLHEHNIVHGDLKPENIML---------------------------- 326
Query: 452 KRKILINP-EVKLIDFGSAVFYNEYHPPV-VSTRHYRAPEIVLGLGWSFPCDIWSIACVL 509
L NP +VKL DFG + F YH V + YRAPE + ++ D+WS C +
Sbjct: 327 ---NLANPNDVKLGDFGLSRFAKPYHDHVQCQSMFYRAPEAFVRGRYNGATDMWSFGCTV 383
Query: 510 VELVTGESLYPIHENTEHMAMMQRINN 536
E+V+G+ + +MQ + N
Sbjct: 384 AEMVSGKIFLAGDNCDDQFYLMQEVIN 410
>SPCC16C4.11 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 288
Score = 87.4 bits (215), Expect = 7e-17
Identities = 67/252 (26%), Positives = 115/252 (45%), Gaps = 43/252 (17%)
Query: 289 FQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKENDRSGQ 348
+Q ++ LG+GT+ V K ++ + VA+K+IR +D T +R + +KE
Sbjct: 3 YQRLEKLGEGTYAHVYKGQNRVTGEIVALKVIR-IDADEGTPSTAIREISLMKELRHPN- 60
Query: 349 YQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNG-YARFPGSHVQAIGKQLVRSVCFLH 407
+ L + +N + LV + + + +M G P S V+ +QL++ + F H
Sbjct: 61 --IMSLSDVLQTENKLMLVFEYMEKDLKKYMDTYGNQGALPPSQVKNFTQQLLKGISFCH 118
Query: 408 DLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKLIDFG 467
+ ++H DLKP+N+LI E+KL DFG
Sbjct: 119 ENRVLHRDLKPQNLLINS--------------------------------RGELKLADFG 146
Query: 468 SA----VFYNEYHPPVVSTRHYRAPEIVLGLG-WSFPCDIWSIACVLVELVTGESLYPIH 522
A + N + VV T YRAP+++LG +S DIWS+ C++ E+ TG L+
Sbjct: 147 LARSIGIPVNTFSNEVV-TLWYRAPDVLLGSRVYSTSIDIWSVGCIMAEMATGRPLFAGS 205
Query: 523 ENTEHMAMMQRI 534
N + + + R+
Sbjct: 206 NNEDQLLKIFRL 217
>CE06686 [T] KOG0660 Mitogen-activated protein kinase
Length = 377
Score = 87.0 bits (214), Expect = 9e-17
Identities = 75/288 (26%), Positives = 128/288 (44%), Gaps = 54/288 (18%)
Query: 270 TDEEGHYVYQENDIF--AKNRFQAMQLLGQGTFGKVVKCKDYLNDITVAVK--------I 319
T EG+YV + N N + + +G G +G V + + VA+K I
Sbjct: 14 TPREGYYVVELNRSVWVVPNYYINLTPIGTGAYGTVCAAECTRSGTRVAIKKFNRPFQSI 73
Query: 320 IRAVDRYRQAAKTELRVLQTIKENDRSGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFM 379
I A YR ELR+L+ + + E + + V+ L G + + +
Sbjct: 74 IHARRTYR-----ELRLLRCMCHENIIDLLDVFTPNENVNDIEDVYFVSMLMGADLSNIL 128
Query: 380 TNNGYARFPGSHVQAIGKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIID 439
R H+Q + Q++R + ++H IIH DLKP NI + +E C
Sbjct: 129 K---IQRLNDDHIQFLVYQILRGLKYIHSADIIHRDLKPSNIAV-NEDC----------- 173
Query: 440 SLTERRKLASGGKRKILINPEVKLIDFGSAVFYNEYHPPVVSTRHYRAPEIVLG-LGWSF 498
E+K++DFG A + V+TR YRAPEI+L + ++
Sbjct: 174 --------------------ELKILDFGLARQTDSEMTGYVATRWYRAPEIMLNWMHYTQ 213
Query: 499 PCDIWSIACVLVELVTGESLYPIHENTEHMAMMQRIN---NEKFPKKM 543
D+WS+ C+L EL+TG++L+P ++ + + + + +E+F KK+
Sbjct: 214 TVDVWSVGCILAELITGKTLFPGSDHIDQLTRIMSVTGTPDEEFLKKI 261
>7303073 [T] KOG1290 Serine/threonine protein kinase
Length = 748
Score = 87.0 bits (214), Expect = 9e-17
Identities = 50/170 (29%), Positives = 94/170 (54%), Gaps = 8/170 (4%)
Query: 274 GHYVYQENDIFAKNRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTE 333
G++ D+F +R+ ++ LG G F V C D VA+KI+++ + + A+ E
Sbjct: 156 GYHPVNIGDLF-HDRYHVIRKLGWGHFSTVWLCWDLQAMGYVAIKIVKSAPHFAETARDE 214
Query: 334 LRVLQTIKENDRSGQYQCLLLREFFDYK------NHICLVTDLYGRSVYDFMTNNGYARF 387
+++L+T++E D S + ++ D+K HIC+V ++ G ++ + + Y
Sbjct: 215 IKILKTVRETDPSNPRRHKTVQMLDDFKITGVNGTHICMVFEVLGDNLLKLIRKSNYRGI 274
Query: 388 PGSHVQAIGKQLVRSVCFLHD-LGIIHTDLKPENILICDETCVEQSLPME 436
P ++V+ I +Q++ + +LH IIHTD+KPEN+L+C + +SL E
Sbjct: 275 PLANVKTITRQVLEGLDYLHTCCKIIHTDIKPENVLLCVDEPHVRSLATE 324
Score = 60.1 bits (144), Expect = 1e-08
Identities = 25/70 (35%), Positives = 42/70 (59%)
Query: 458 NPEVKLIDFGSAVFYNEYHPPVVSTRHYRAPEIVLGLGWSFPCDIWSIACVLVELVTGES 517
N VK+ D G+A + + + + TR YR+ E+++G G++ DIWS AC++ EL TG+
Sbjct: 593 NVHVKIADLGNACWVDRHFTEDIQTRQYRSLEVIIGAGYNTSADIWSTACMVFELATGDY 652
Query: 518 LYPIHENTEH 527
L+ H +
Sbjct: 653 LFEPHSGESY 662
>YLR113w [T] KOG0660 Mitogen-activated protein kinase
Length = 435
Score = 86.3 bits (212), Expect = 1e-16
Identities = 70/246 (28%), Positives = 105/246 (42%), Gaps = 38/246 (15%)
Query: 287 NRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKENDRS 346
NR+ + +G G FG V D L VA+K I AK R L+ +K R
Sbjct: 21 NRYNDLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTAVLAKRTYRELKLLKHL-RH 79
Query: 347 GQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQLVRSVCFL 406
CL F I VT+L G ++ + + VQ Q++R + ++
Sbjct: 80 ENLICLQ-DIFLSPLEDIYFVTELQGTDLHRLLQTRPLEK---QFVQYFLYQILRGLKYV 135
Query: 407 HDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKLIDF 466
H G+IH DLKP NILI +E C ++K+ DF
Sbjct: 136 HSAGVIHRDLKPSNILI-NENC-------------------------------DLKICDF 163
Query: 467 GSAVFYNEYHPPVVSTRHYRAPEIVL-GLGWSFPCDIWSIACVLVELVTGESLYPIHENT 525
G A + VSTR+YRAPEI+L + DIWS C+ E++ G+ L+P ++
Sbjct: 164 GLARIQDPQMTGYVSTRYYRAPEIMLTWQKYDVEVDIWSAGCIFAEMIEGKPLFPGKDHV 223
Query: 526 EHMAMM 531
+++
Sbjct: 224 HQFSII 229
>Hs16936528 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 298
Score = 86.3 bits (212), Expect = 1e-16
Identities = 65/236 (27%), Positives = 105/236 (43%), Gaps = 39/236 (16%)
Query: 289 FQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKENDRSGQ 348
FQ ++ +G+GT+G V K ++ L VA+K IR T +R + +KE +
Sbjct: 4 FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNI 63
Query: 349 YQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQLVRSVCFLHD 408
+ L + +N + LV + + + FM + P +++ QL++ + F H
Sbjct: 64 VKLL---DVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHS 120
Query: 409 LGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKLIDFGS 468
++H DLKP+N+LI E +KL DFG
Sbjct: 121 HRVLHRDLKPQNLLINTEGA--------------------------------IKLADFGL 148
Query: 469 AVFYN---EYHPPVVSTRHYRAPEIVLGLG-WSFPCDIWSIACVLVELVTGESLYP 520
A + + V T YRAPEI+LG +S DIWS+ C+ E+VT +L+P
Sbjct: 149 ARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFP 204
>YGR040w [T] KOG0660 Mitogen-activated protein kinase
Length = 368
Score = 85.9 bits (211), Expect = 2e-16
Identities = 63/239 (26%), Positives = 115/239 (47%), Gaps = 27/239 (11%)
Query: 287 NRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKT--ELRVLQTIKEND 344
++++ + L+G+G +G V + I VA+K I+ + +T E+++L+ E++
Sbjct: 11 SQYKLVDLIGEGAYGTVCSAIHKPSGIKVAIKKIQPFSKKLFVTRTIREIKLLRYFHEHE 70
Query: 345 RSGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTN--NGYARFPGSHVQAIGKQLVRS 402
+ D N + LV +L + + N +G++ HVQ Q++R+
Sbjct: 71 NIISILDKVRPVSIDKLNAVYLVEELMETDLQKVINNQNSGFSTLSDDHVQYFTYQILRA 130
Query: 403 VCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVK 462
+ +H +IH D+KP N+L+ + +++ D R +S R+ L+
Sbjct: 131 LKSIHSAQVIHRDIKPSNLLL------NSNCDLKVCDFGLARCLASSSDSRETLVG---- 180
Query: 463 LIDFGSAVFYNEYHPPVVSTRHYRAPEIVLGL-GWSFPCDIWSIACVLVELVTGESLYP 520
F EY V+TR YRAPEI+L ++ DIWS C+L E+V+G+ L+P
Sbjct: 181 --------FMTEY----VATRWYRAPEIMLTFQEYTTAMDIWSCGCILAEMVSGKPLFP 227
>Hs4758652 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 358
Score = 84.7 bits (208), Expect = 4e-16
Identities = 71/291 (24%), Positives = 136/291 (46%), Gaps = 49/291 (16%)
Query: 288 RFQAMQLLGQGTFGKVVKCKDYLNDITVAVK-IIRAVDR--YRQAAKTELRVLQTIKEND 344
+++ + +G+G++G V KC++ VA+K + + D ++ A E+R+L+ +K +
Sbjct: 4 KYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQLKHPN 63
Query: 345 RSGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSH-VQAIGKQLVRSV 403
+ L E F K + LV + +V + Y R H V++I Q +++V
Sbjct: 64 ------LVNLLEVFRRKRRLHLVFEYCDHTVLHELDR--YQRGVPEHLVKSITWQTLQAV 115
Query: 404 CFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKL 463
F H IH D+KPENILI + + KL G ++L P
Sbjct: 116 NFCHKHNCIHRDVKPENILITKHSVI----------------KLCDFGFARLLTGP---- 155
Query: 464 IDFGSAVFYNEYHPPVVSTRHYRAPEIVLG-LGWSFPCDIWSIACVLVELVTGESLYPIH 522
++Y+ V+TR YR+PE+++G + P D+W+I CV EL++G L+P
Sbjct: 156 ---------SDYYTDYVATRWYRSPELLVGDTQYGPPVDVWAIGCVFAELLSGVPLWPGK 206
Query: 523 ENTEHMAMMQRINNEKFPKKMVEKMFFKVENKYGSI----PTDLQTSVVKY 569
+ + + ++++ + P+ + F + + P D++ +K+
Sbjct: 207 SDVDQLYLIRKTLGDLIPR---HQQVFSTNQYFSGVKIPDPEDMEPLELKF 254
>Hs20562757 [T] KOG0660 Mitogen-activated protein kinase
Length = 379
Score = 84.7 bits (208), Expect = 4e-16
Identities = 67/294 (22%), Positives = 126/294 (42%), Gaps = 45/294 (15%)
Query: 288 RFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDR--YRQAAKTELRVLQTIKENDR 345
R+ +Q +G+G +G V D++ VA+K I + Y Q E+++L + +
Sbjct: 41 RYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRFRHENV 100
Query: 346 SGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQLVRSVCF 405
G + +L + + +V DL +Y + + + H+ Q++R + +
Sbjct: 101 IG-IRDILRASTLEAMRDVYIVQDLMETDLYKLLKSQ---QLSNDHICYFLYQILRGLKY 156
Query: 406 LHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKLID 465
+H ++H DLKP N+LI + TC ++K+ D
Sbjct: 157 IHSANVLHRDLKPSNLLI-NTTC-------------------------------DLKICD 184
Query: 466 FGSAVFYNEYH------PPVVSTRHYRAPEIVL-GLGWSFPCDIWSIACVLVELVTGESL 518
FG A + H V+TR YRAPEI+L G++ DIWS+ C+L E+++ +
Sbjct: 185 FGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPI 244
Query: 519 YPIHENTEHMAMMQRINNEKFPKKMVEKMFFKVENKYGSIPTDLQTSVVKYFDR 572
+P + + + I + + + K N S+P+ + + K F +
Sbjct: 245 FPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPK 298
>CE27574 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 463
Score = 84.3 bits (207), Expect = 6e-16
Identities = 62/246 (25%), Positives = 108/246 (43%), Gaps = 41/246 (16%)
Query: 280 ENDIFAKNRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDR---YRQAAKTELRV 336
E + R+Q ++L+G G G V D + + VA+K + + + + A EL++
Sbjct: 110 EAQMVVLKRYQNLRLIGSGAQGIVCSAFDTVRNEQVAIKKLSRPFQNVTHAKRAYRELKL 169
Query: 337 LQTIKENDRSGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIG 396
+ + + G C ++ D N + +V +L ++ + + + +
Sbjct: 170 MSLVNHKNIIGILNCFTPQKKLDEFNDLYIVMELMDANLCQVIQMD----LDHERLSYLL 225
Query: 397 KQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKIL 456
Q++ + LH GIIH DLKP NI++ + +
Sbjct: 226 YQMLCGIRHLHSAGIIHRDLKPSNIVVRSDCTL--------------------------- 258
Query: 457 INPEVKLIDFGSAVFYNEYH--PPVVSTRHYRAPEIVLGLGWSFPCDIWSIACVLVELVT 514
K++DFG A E P V TR+YRAPE++LG+G+ D+WSI C+ EL+
Sbjct: 259 -----KILDFGLARTAIEAFMMTPYVVTRYYRAPEVILGMGYKENVDVWSIGCIFGELIR 313
Query: 515 GESLYP 520
G L+P
Sbjct: 314 GRVLFP 319
>Hs4507221 [T] KOG1290 Serine/threonine protein kinase
Length = 686
Score = 84.0 bits (206), Expect = 7e-16
Identities = 46/158 (29%), Positives = 90/158 (56%), Gaps = 8/158 (5%)
Query: 274 GHYVYQENDIFAKNRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTE 333
G++ + D+F R+ ++ LG G F V C D VA+K++++ Y + A E
Sbjct: 67 GYHPVKIGDLF-NGRYHVIRKLGWGHFSTVWLCWDMQGKRFVAMKVVKSAQHYTETALDE 125
Query: 334 LRVLQTIKENDRSGQYQCLLLREFFDYK------NHICLVTDLYGRSVYDFMTNNGYARF 387
+++L+ ++E+D S + ++++ D+K H+C+V ++ G + ++ + Y
Sbjct: 126 IKLLKCVRESDPSDPNKDMVVQLIDDFKISGMNGIHVCMVFEVLGHHLLKWIIKSNYQGL 185
Query: 388 PGSHVQAIGKQLVRSVCFLHD-LGIIHTDLKPENILIC 424
P V++I +Q+++ + +LH IIHTD+KPENIL+C
Sbjct: 186 PVRCVKSIIRQVLQGLDYLHSKCKIIHTDIKPENILMC 223
Score = 64.3 bits (155), Expect = 6e-10
Identities = 46/152 (30%), Positives = 71/152 (46%), Gaps = 34/152 (22%)
Query: 455 ILINP---------EVKLIDFGSAVFYNEYHPPVVSTRHYRAPEIVLGLGWSFPCDIWSI 505
+L+NP VK+ D G+A + +++ + TR YR+ E+++G G+S P DIWS
Sbjct: 510 LLVNPLDPRNRDKIRVKIADLGNACWVHKHFTEDIQTRQYRSIEVLIGAGYSTPADIWST 569
Query: 506 ACVLVELVTGESLYPIHENTEHMAMMQRINNEKFPKKMVEKMFFKVENKYGSIPTD--LQ 563
AC+ EL TG+ L+ H ++ +E ++E + GSIP L
Sbjct: 570 ACMAFELATGDYLFEPHSGEDYS------RDEDHIAHIIELL--------GSIPRHFALS 615
Query: 564 TSVVKYFDRQTGELRWPLRNSKGQVITKEKSW 595
+ F + GELR ITK K W
Sbjct: 616 GKYSREFFNRRGELRH---------ITKLKPW 638
>CE26621 [T] KOG0671 LAMMER dual specificity kinases
Length = 393
Score = 84.0 bits (206), Expect = 7e-16
Identities = 73/258 (28%), Positives = 121/258 (46%), Gaps = 37/258 (14%)
Query: 292 MQLLGQGTFGKVVKCKDYLNDITVAVKIIRA-------VDRYRQAAKTELRVLQTIKEND 344
+ +LG+G FG V + D A+K+ +A D R++ + LQ +K
Sbjct: 53 VSVLGEGVFGTVFEVADAEKKKKFALKLFKAGHTQFGCEDWVRESELSIPNYLQIMKSVA 112
Query: 345 RSGQYQCLLLREFFDYKN------HICLVTDLYGRSVYDFMTN------NGYARFPGSHV 392
+ + L + + I ++ +L G+S++ M + N FP + +
Sbjct: 113 AAHHPNLIKLVKSGKMASVPEGYLRIAILMELRGKSLFSVMDSTKSEVPNKEISFPIATI 172
Query: 393 QAIGKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGK 452
+ IG Q++ ++ L + I+H DLKPENI TC + + + ++ +L
Sbjct: 173 REIGAQILSAMKKLEKMEIVHLDLKPENICFTS-TCTFTTEIRKDVCYISPSEEL----- 226
Query: 453 RKILINPEVKLIDFGSAVFYNEYH---PPVVSTRHYRAPEIVLGLGWSFPCDIWSIACVL 509
V +IDFG+A N+ VV T++YRAPEI +GL +S D+WS C+L
Sbjct: 227 -------NVCIIDFGNARKSNQEDLKSSEVVQTQNYRAPEIFMGLPFSTRSDVWSFGCIL 279
Query: 510 VELVTGESLYPIHENTEH 527
EL TGE L+ + N EH
Sbjct: 280 SELYTGELLF--YGNDEH 295
>CE00315 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 332
Score = 84.0 bits (206), Expect = 7e-16
Identities = 65/253 (25%), Positives = 112/253 (43%), Gaps = 42/253 (16%)
Query: 273 EGHYVYQENDIFAKNRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKT 332
EG ++ + ++ N F ++ +G+GT+G V K K+ + VA+K IR T
Sbjct: 6 EGEVAHEGDSVYTLNDFTKLEKIGEGTYGVVYKGKNRRTNAMVAMKKIRLESEDEGVPST 65
Query: 333 ELRVLQTIKENDRSGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARF-PGSH 391
+R + +KE + L +N + L+ + + +M G + P
Sbjct: 66 AVREISLLKELQHP---NVVGLEAVIMQENRLFLIFEFLSFDLKRYMDQLGKDEYLPLET 122
Query: 392 VQAIGKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGG 451
+++ Q+++++CF H +IH DLKP+N+L+ +
Sbjct: 123 LKSYTFQILQAMCFCHQRRVIHRDLKPQNLLVDN-------------------------- 156
Query: 452 KRKILINPEVKLIDFGSA----VFYNEYHPPVVSTRHYRAPEIVLGL-GWSFPCDIWSIA 506
N +KL DFG A + Y VV T YRAPEI++G +S D+WSI
Sbjct: 157 ------NGAIKLADFGLARAIGIPIRVYTHEVV-TLWYRAPEILMGAQRYSMGVDMWSIG 209
Query: 507 CVLVELVTGESLY 519
C+ E+ T + L+
Sbjct: 210 CIFAEMATKKPLF 222
>Hs7705551 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 632
Score = 83.6 bits (205), Expect = 1e-15
Identities = 61/237 (25%), Positives = 106/237 (43%), Gaps = 40/237 (16%)
Query: 287 NRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKENDRS 346
NR+ ++ LG GT+G V+ + + +A+K ++ + + E + +K +
Sbjct: 2 NRYTTIRQLGDGTYGSVLLGRSIESGELIAIKKMKR----KFYSWEECMNQREVKSLKKL 57
Query: 347 GQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQLVRSVCFL 406
+ L+E +H+ + + ++Y + FP S ++ I Q+++ + F+
Sbjct: 58 NHANVVKLKEVIRENDHLYFIFEYMKENLYQLIKERNKL-FPESAIRNIMYQILQGLAFI 116
Query: 407 HDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKLIDF 466
H LG H DLKPEN+L C+ L VK+ DF
Sbjct: 117 HKLGFFHRDLKPENLL-----CMGPEL---------------------------VKIADF 144
Query: 467 GSAVFYNEYHP--PVVSTRHYRAPEIVL-GLGWSFPCDIWSIACVLVELVTGESLYP 520
G A P VSTR YRAPE++L +S P D+W++ C++ E+ T L+P
Sbjct: 145 GLAREIRSKPPYTDYVSTRWYRAPEVLLRSTNYSSPIDVWAVGCIMAEVYTLRPLFP 201
>Hs7662388 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 632
Score = 83.2 bits (204), Expect = 1e-15
Identities = 61/237 (25%), Positives = 106/237 (43%), Gaps = 40/237 (16%)
Query: 287 NRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKENDRS 346
NR+ ++ LG GT+G V+ + + +A+K ++ + + E L+ +K +
Sbjct: 2 NRYTTIRQLGDGTYGSVLLGRSIESGELIAIKKMKR----KFYSWEECMNLREVKSLKKL 57
Query: 347 GQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQLVRSVCFL 406
+ L+E +H+ + + ++Y + FP S ++ I Q+++ + F+
Sbjct: 58 NHANVVKLKEVIRENDHLYFIFEYMKENLYQLIKERNKL-FPESAIRNIMYQILQGLAFI 116
Query: 407 HDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKLIDF 466
H G H DLKPEN+L C+ L VK+ DF
Sbjct: 117 HKHGFFHRDLKPENLL-----CMGPEL---------------------------VKIADF 144
Query: 467 GSAVFYNEYHP--PVVSTRHYRAPEIVL-GLGWSFPCDIWSIACVLVELVTGESLYP 520
G A P VSTR YRAPE++L +S P D+W++ C++ E+ T L+P
Sbjct: 145 GLAREIRSKPPYTDYVSTRWYRAPEVLLRSTNYSSPIDVWAVGCIMAEVYTLRPLFP 201
>Hs18552621 [R] KOG0597 Serine-threonine protein kinase FUSED
Length = 1315
Score = 82.8 bits (203), Expect = 2e-15
Identities = 65/232 (28%), Positives = 110/232 (47%), Gaps = 42/232 (18%)
Query: 288 RFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKENDRSG 347
++ ++++G+G+FG+V K + + VA+K I + R ++ ELR LQ E R
Sbjct: 3 KYHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGR----SEKELRNLQREIEIMRGL 58
Query: 348 QYQCLL-LREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQLVRSVCFL 406
++ ++ + + F+ + +VTD ++ + ++G + P VQAI QLV ++ +L
Sbjct: 59 RHPNIVHMLDSFETDKEVVVVTDYAEGELFQILEDDG--KLPEDQVQAIAAQLVSALYYL 116
Query: 407 HDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKLIDF 466
H I+H D+KP+NIL LA GG +KL DF
Sbjct: 117 HSHRILHRDMKPQNIL------------------------LAKGG--------GIKLCDF 144
Query: 467 GSAVFYNEYHPPVVS---TRHYRAPEIVLGLGWSFPCDIWSIACVLVELVTG 515
G A + + S T Y +PE+V + D+WS+ C+L EL G
Sbjct: 145 GFARAMSTNTMVLTSIKGTPLYMSPELVEERPYDHTADLWSVGCILYELAVG 196
>At5g14640 [G] KOG0658 Glycogen synthase kinase-3
Length = 408
Score = 82.8 bits (203), Expect = 2e-15
Identities = 65/252 (25%), Positives = 116/252 (45%), Gaps = 41/252 (16%)
Query: 289 FQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKENDRSGQ 348
+ A +++GQG+FG V + K TVA+K + RY+ EL+ ++ + +
Sbjct: 74 YMAERIVGQGSFGIVFQAKCLETGETVAIKKVLQDKRYK---NRELQTMRLLDHPNVVSL 130
Query: 349 YQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYA--RFPGSHVQAIGKQLVRSVCFL 406
C D + ++ LV + +VY + A R P +V+ Q+ R++ ++
Sbjct: 131 KHCFFSTTEKD-ELYLNLVLEYVPETVYRVSKHYSRANQRMPIIYVKLYTYQICRALAYI 189
Query: 407 H-DLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKLID 465
H +G+ H D+KP+N+L+ T +VKL D
Sbjct: 190 HGGVGVCHRDIKPQNLLVNPHT-------------------------------HQVKLCD 218
Query: 466 FGSAVFYNEYHPPV--VSTRHYRAPEIVLG-LGWSFPCDIWSIACVLVELVTGESLYPIH 522
FGSA + P + + +R+YRAPE++ G ++ DIWS CVL EL+ G+ L+P
Sbjct: 219 FGSAKVLVKGEPNISYICSRYYRAPELIFGATEYTTTIDIWSAGCVLAELLLGQPLFPGE 278
Query: 523 ENTEHMAMMQRI 534
+ + + ++
Sbjct: 279 SGVDQLVEIIKV 290
>7296535 [T] KOG1290 Serine/threonine protein kinase
Length = 880
Score = 82.8 bits (203), Expect = 2e-15
Identities = 51/157 (32%), Positives = 86/157 (54%), Gaps = 8/157 (5%)
Query: 274 GHYVYQENDIFAKNRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTE 333
G++ DIF NRF+ ++ LG G F V C+D ++ VA+K++++ Y + A E
Sbjct: 218 GYHPVVIGDIF-DNRFRVVRKLGWGHFSTVWLCRDLKDEKYVALKVVKSAPHYIETAADE 276
Query: 334 LRVLQTIKENDRSG--QYQCLLLREFFDYKN----HICLVTDLYGRSVYDFMTNNGYARF 387
+R+L+ I++ D + + + L F + H CLV + G S+Y + N Y
Sbjct: 277 IRLLEAIRDADPMDVKRERIVRLMNHFTVRGVNGMHTCLVFEALGCSLYKLIVKNNYQGL 336
Query: 388 PGSHVQAIGKQLVRSVCFLHD-LGIIHTDLKPENILI 423
+ V+ I +Q++ + +LH IIHTD+KPENIL+
Sbjct: 337 AIAQVRNIIRQVLEGLDYLHSKCSIIHTDIKPENILL 373
Score = 58.2 bits (139), Expect = 4e-08
Identities = 56/229 (24%), Positives = 86/229 (37%), Gaps = 69/229 (30%)
Query: 458 NPEVKLIDFGSAVFYNEYHPPVVSTRHYRAPEIVLGLGWSFPCDIWSIACVLVELVTGES 517
N VK+ D G+A + + + TR YR+ E++LG +++ DIWS AC+ EL TG+
Sbjct: 711 NVRVKIADLGNACYDYHHFTEDIQTRQYRSIEVLLGAPYNYTADIWSTACLAFELATGDY 770
Query: 518 LYPIHENTEHMAMMQRINNEKFPKKMVEKMFFKVENKYGSIPTDL---QTSVVKYFDRQT 574
L+ H + +E +VE + GSIP + +KYF
Sbjct: 771 LFDPHAGESYS------RDEDHLAHIVELL--------GSIPQSVIFRGKHGLKYFTSYG 816
Query: 575 GELRWPLRNSKGQVITKEKSWKRILATCDRLDVFISKKLQMDYGSWLEIHWDMQLEDNWR 634
LRN ITK K W + ++ D W
Sbjct: 817 S-----LRN-----ITKLKPWSLMNVLVEKYD--------------------------WD 840
Query: 635 LILSKNIDSRNIDKNVFMFWYYFVDLCRKMFEFDPTKRITAKEVIEHEW 683
+ +K F D M E++P R +A E ++H W
Sbjct: 841 PVEAKK----------------FSDFLLPMLEYNPVIRASAAECLQHPW 873
>HsM4504163 [G] KOG0658 Glycogen synthase kinase-3
Length = 420
Score = 82.4 bits (202), Expect = 2e-15
Identities = 66/241 (27%), Positives = 113/241 (46%), Gaps = 55/241 (22%)
Query: 293 QLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKENDRSGQYQCL 352
+++G G+FG V + K + VA+K + R++ R LQ +++ D C
Sbjct: 60 KVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKN------RELQIMRKLDH-----CN 108
Query: 353 LLR-EFFDYKN-------HICLVTDLYGRSVYDFMTNNGYAR--FPGSHVQAIGKQLVRS 402
++R +F Y + ++ LV D +VY + A+ P +V+ QL RS
Sbjct: 109 IVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRS 168
Query: 403 VCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVK 462
+ ++H GI H D+KP+N+L+ +T V +K
Sbjct: 169 LAYIHSFGICHRDIKPQNLLLDPDTAV-------------------------------LK 197
Query: 463 LIDFGSA--VFYNEYHPPVVSTRHYRAPEIVLG-LGWSFPCDIWSIACVLVELVTGESLY 519
L DFGSA + E + + +R+YRAPE++ G ++ D+WS CVL EL+ G+ ++
Sbjct: 198 LCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIF 257
Query: 520 P 520
P
Sbjct: 258 P 258
>Hs7657629 [T] KOG1290 Serine/threonine protein kinase
Length = 533
Score = 82.4 bits (202), Expect = 2e-15
Identities = 55/203 (27%), Positives = 107/203 (52%), Gaps = 14/203 (6%)
Query: 235 SNSASKSP-SRFTKILKKSPLLGSHQDKLRSMDRFKTDEE-----GHYVYQENDIFAKNR 288
S+ AS P S +++ +P+ Q L S D + D + G++ + D+F R
Sbjct: 20 SSQASCGPESSGSELALATPVPQMLQGLLGSDDEEQEDPKDYCKGGYHPVKIGDVF-NGR 78
Query: 289 FQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKENDRSGQ 348
+ ++ LG G F V C D VA+K++++ Y + A E+++L+ ++++D S
Sbjct: 79 YHVVRKLGWGHFSTVWLCWDIQRKRFVALKVVKSAGHYTETAVDEIKLLKCVRDSDPSDP 138
Query: 349 YQCLLLREFFDYK------NHICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQLVRS 402
+ +++ D++ H+C+V ++ G + ++ + Y P V++I +Q++
Sbjct: 139 KRETIVQLIDDFRISGVNGVHVCMVLEVLGHQLLKWIIKSNYQGLPVPCVKSIVRQVLHG 198
Query: 403 VCFLH-DLGIIHTDLKPENILIC 424
+ +LH IIHTD+KPENIL+C
Sbjct: 199 LDYLHTKCKIIHTDIKPENILLC 221
Score = 60.8 bits (146), Expect = 7e-09
Identities = 28/86 (32%), Positives = 48/86 (55%), Gaps = 9/86 (10%)
Query: 451 GKRKILINP---------EVKLIDFGSAVFYNEYHPPVVSTRHYRAPEIVLGLGWSFPCD 501
G +L+NP ++K+ D G+A + +++ + TR YRA E+++G + P D
Sbjct: 352 GASNLLVNPLEPQNADKIKIKIADLGNACWVHKHFTEDIQTRQYRAVEVLIGAEYGPPAD 411
Query: 502 IWSIACVLVELVTGESLYPIHENTEH 527
IWS AC+ EL TG+ L+ H ++
Sbjct: 412 IWSTACMAFELATGDYLFEPHSGEDY 437
>Hs21361340 [G] KOG0658 Glycogen synthase kinase-3
Length = 433
Score = 82.4 bits (202), Expect = 2e-15
Identities = 66/241 (27%), Positives = 113/241 (46%), Gaps = 55/241 (22%)
Query: 293 QLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKENDRSGQYQCL 352
+++G G+FG V + K + VA+K + R++ R LQ +++ D C
Sbjct: 60 KVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKN------RELQIMRKLDH-----CN 108
Query: 353 LLR-EFFDYKN-------HICLVTDLYGRSVYDFMTNNGYAR--FPGSHVQAIGKQLVRS 402
++R +F Y + ++ LV D +VY + A+ P +V+ QL RS
Sbjct: 109 IVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRS 168
Query: 403 VCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVK 462
+ ++H GI H D+KP+N+L+ +T V +K
Sbjct: 169 LAYIHSFGICHRDIKPQNLLLDPDTAV-------------------------------LK 197
Query: 463 LIDFGSA--VFYNEYHPPVVSTRHYRAPEIVLG-LGWSFPCDIWSIACVLVELVTGESLY 519
L DFGSA + E + + +R+YRAPE++ G ++ D+WS CVL EL+ G+ ++
Sbjct: 198 LCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIF 257
Query: 520 P 520
P
Sbjct: 258 P 258
>CE19353_3 [T] KOG0671 LAMMER dual specificity kinases
Length = 343
Score = 82.0 bits (201), Expect = 3e-15
Identities = 71/249 (28%), Positives = 114/249 (45%), Gaps = 47/249 (18%)
Query: 295 LGQGTFGKVVKCKDYLNDITVAVKIIRAVDRY--RQAAKTELRVLQTIKENDRSGQYQCL 352
LG+G FG V K D+ N AVK+ + Q+ E +++ + + +
Sbjct: 13 LGEGVFGAVYKVVDHSNK-KYAVKLFKEEHSEVGEQSWARETAIMKAVTAINSAN----- 66
Query: 353 LLREFFDYKNH---------ICLVTDLYGRSVYDFMTNNGYARFPGSHV-------QAIG 396
L+R ++ + I + +L GRSV++ M + GS + + +G
Sbjct: 67 LIRMEDSWRINESVPNGFLKIAISFELKGRSVFEVMDSTKGKMPAGSEISFEINAIRVMG 126
Query: 397 KQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKIL 456
KQL+ ++ L + I+H DLKPENI + ++ +
Sbjct: 127 KQLLEAMEKLESVKIVHLDLKPENICFSSSCTFKTTVTGNVC-----------------F 169
Query: 457 INPE---VKLIDFGSAVFYNEYHPP---VVSTRHYRAPEIVLGLGWSFPCDIWSIACVLV 510
I P V ++DFG+A + PP +V T++YRAPEI LGL +S DIWS C+L
Sbjct: 170 IQPSIFHVCVVDFGNARTIRQDKPPKYALVQTQNYRAPEIFLGLPFSVKSDIWSFGCILS 229
Query: 511 ELVTGESLY 519
EL TG+ L+
Sbjct: 230 ELYTGDLLF 238
>CE02602_1 [T] KOG0660 Mitogen-activated protein kinase
Length = 342
Score = 82.0 bits (201), Expect = 3e-15
Identities = 78/257 (30%), Positives = 117/257 (45%), Gaps = 28/257 (10%)
Query: 281 NDIFA--KNRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQ 338
ND+F ++ A + LG G FG V + D + VA+K I V + + AK LR ++
Sbjct: 34 NDLFCLEATQYLAQENLGAGAFGVVCRAIDSKLNKQVAIKKITRVFKNQSTAKCALREIR 93
Query: 339 TIKENDRSGQYQC--LLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIG 396
+E +L+RE ++ I +V DL + + +N H Q
Sbjct: 94 ITRELSHENIINSTDVLMRESGSGQD-IYIVMDLMETDLLSVLKSN--QTLNEKHFQYFF 150
Query: 397 KQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKIL 456
Q+++ + +LH GIIH DLKP N+L+ +E C ++I D R SG K
Sbjct: 151 YQILKGLKYLHSAGIIHRDLKPANLLL-NEDC-----SLKIADFGMSR----SGPSTKTT 200
Query: 457 INPEVKLIDFGSAVFYNEYHPPVVSTRHYRAPEIVLGLG-WSFPCDIWSIACVLVELVTG 515
N G Y VST YRAPEI+L +G + DIWS C+L E++
Sbjct: 201 PNTSPNAHISGDLSQY-------VSTLWYRAPEILLSMGEYDTQVDIWSAGCILAEMLL- 252
Query: 516 ESLYPIHENTEHMAMMQ 532
L PI T+ + +Q
Sbjct: 253 --LRPIFTGTDSYSQIQ 267
>Hs11496279 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 623
Score = 81.6 bits (200), Expect = 4e-15
Identities = 63/237 (26%), Positives = 105/237 (43%), Gaps = 40/237 (16%)
Query: 287 NRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKENDRS 346
NR+ M+ LG GT+G V+ K + VA+K ++ + + E L+ +K +
Sbjct: 2 NRYTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKR----KFYSWDECMNLREVKSLKKL 57
Query: 347 GQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQLVRSVCFL 406
+ L+E +H+ + + ++Y M + FP S ++ I Q+++ + F+
Sbjct: 58 NHANVIKLKEVIRENDHLYFIFEYMKENLYQLMKDRNKL-FPESVIRNIMYQILQGLAFI 116
Query: 407 HDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKLIDF 466
H G H D+KPEN+L C+ L VK+ DF
Sbjct: 117 HKHGFFHRDMKPENLL-----CMGPEL---------------------------VKIADF 144
Query: 467 GSAVFYNEYHP--PVVSTRHYRAPEIVLGLG-WSFPCDIWSIACVLVELVTGESLYP 520
G A P VSTR YRAPE++L +S P D+W++ ++ EL L+P
Sbjct: 145 GLARELRSQPPYTDYVSTRWYRAPEVLLRSSVYSSPIDVWAVGSIMAELYMLRPLFP 201
>7302908 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 317
Score = 81.6 bits (200), Expect = 4e-15
Identities = 59/239 (24%), Positives = 102/239 (41%), Gaps = 39/239 (16%)
Query: 289 FQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKENDRSGQ 348
+Q + ++G+G +G V + +D + VA+K +R + LR + +K+ + S
Sbjct: 26 YQELNIIGEGAYGTVYRARDVITGNIVALKKVRISLNENGVPMSTLREISLLKQLNASNH 85
Query: 349 YQCLLLREFFDYKNH-----ICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQLVRSV 403
+ L E + I LV + + + D + + +Q + ++L+ V
Sbjct: 86 ANIVKLYEVCQFLERDGQLLILLVFEHVEQDLSDLIDRLPKSGMSPPTIQRLSRELLTGV 145
Query: 404 CFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKL 463
FLH IIH DLKP+N+L+ + +K+
Sbjct: 146 DFLHSHRIIHRDLKPQNLLVSSQ--------------------------------GHLKI 173
Query: 464 IDFGSAVFYNEYH--PPVVSTRHYRAPEIVLGLGWSFPCDIWSIACVLVELVTGESLYP 520
DFG A Y VV T YRAPE++L ++ DIWS AC++ E+ +L+P
Sbjct: 174 ADFGLAKTYGSEMKLTSVVVTLWYRAPEVLLAQPYNSTVDIWSAACIIFEMFNRRALFP 232
>Hs4506785 [T] KOG0660 Mitogen-activated protein kinase
Length = 367
Score = 80.9 bits (198), Expect = 6e-15
Identities = 61/263 (23%), Positives = 118/263 (44%), Gaps = 40/263 (15%)
Query: 289 FQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAV---DRYRQAAKTELRVLQTIKENDR 345
++ +Q +G G +G V D VA+K + + + + A ELR+L+ ++ +
Sbjct: 27 YRDLQPVGSGAYGAVCSAVDGRTGAKVAIKKLYRPFQSELFAKRAYRELRLLKHMRHENV 86
Query: 346 SGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQLVRSVCF 405
G E D LV G + M + + +Q + Q+++ + +
Sbjct: 87 IGLLDVFTPDETLDDFTDFYLVMPFMGTDLGKLMKHE---KLGEDRIQFLVYQMLKGLRY 143
Query: 406 LHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKLID 465
+H GIIH DLKP N+ + +E C E+K++D
Sbjct: 144 IHAAGIIHRDLKPGNLAV-NEDC-------------------------------ELKILD 171
Query: 466 FGSAVFYNEYHPPVVSTRHYRAPEIVLG-LGWSFPCDIWSIACVLVELVTGESLYPIHEN 524
FG A + V TR YRAPE++L + ++ DIWS+ C++ E++TG++L+ ++
Sbjct: 172 FGLARQADSEMTGYVVTRWYRAPEVILNWMRYTQTVDIWSVGCIMAEMITGKTLFKGSDH 231
Query: 525 TEHMAMMQRINNEKFPKKMVEKM 547
+ + + ++ P + V+++
Sbjct: 232 LDQLKEIMKVTGTP-PAEFVQRL 253
>7301110 [T] KOG0660 Mitogen-activated protein kinase
Length = 366
Score = 80.9 bits (198), Expect = 6e-15
Identities = 66/253 (26%), Positives = 110/253 (43%), Gaps = 45/253 (17%)
Query: 289 FQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKENDRSGQ 348
+Q +Q +G G +G+V K ++ VA+K + + AK R L+ +K D
Sbjct: 25 YQDLQPVGSGAYGQVSKAVVRGTNMHVAIKKLARPFQSAVHAKRTYRELRLLKHMDHENV 84
Query: 349 YQCLLL------REFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQLVRS 402
L + + + LVT L + + + HVQ + Q++R
Sbjct: 85 IGLLDIFHPHPANGSLENFQQVYLVTHLMDADLNNIIRMQ---HLSDDHVQFLVYQILRG 141
Query: 403 VCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVK 462
+ ++H G+IH DLKP NI + +E C E++
Sbjct: 142 LKYIHSAGVIHRDLKPSNIAV-NEDC-------------------------------ELR 169
Query: 463 LIDFGSAVFYNEYHPPVVSTRHYRAPEIVLG-LGWSFPCDIWSIACVLVELVTGESLYPI 521
++DFG A V+TR YRAPEI+L + + DIWS+ C++ EL+T +L+P
Sbjct: 170 ILDFGLARPTENEMTGYVATRWYRAPEIMLNWMHYDQTVDIWSVGCIMAELITRRTLFP- 228
Query: 522 HENTEHMAMMQRI 534
T+H+ + I
Sbjct: 229 --GTDHIHQLNLI 239
>Hs7706059 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 455
Score = 80.5 bits (197), Expect = 8e-15
Identities = 65/234 (27%), Positives = 108/234 (45%), Gaps = 37/234 (15%)
Query: 289 FQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAA-KTELRVLQTIKENDRSG 347
++ + +G+G++G V+KCK VA+KI +R Q+ K +R ++ +K+
Sbjct: 4 YETLGKVGEGSYGTVMKCKHKNTGQIVAIKIF--YERPEQSVNKIAMREIKFLKQFHHEN 61
Query: 348 QYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQLVRSVCFLH 407
+ E F K I LV + +V D + + + ++ Q++R++ +LH
Sbjct: 62 LVNLI---EVFRQKKKIHLVFEFIDHTVLDELQHYCHG-LESKRLRKYLFQILRAIDYLH 117
Query: 408 DLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKLIDFG 467
IIH D+KPENIL+ S + KL G + L P
Sbjct: 118 SNNIIHRDIKPENILV----------------SQSGITKLCDFGFARTLAAP-------- 153
Query: 468 SAVFYNEYHPPVVSTRHYRAPEIVL-GLGWSFPCDIWSIACVLVELVTGESLYP 520
Y +Y V+TR YRAPE+VL + P DIW++ C+++E+ TG P
Sbjct: 154 -GDIYTDY----VATRWYRAPELVLKDTSYGKPVDIWALGCMIIEMATGNPYLP 202
>Hs20986531 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 80.5 bits (197), Expect = 8e-15
Identities = 58/242 (23%), Positives = 105/242 (42%), Gaps = 45/242 (18%)
Query: 288 RFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDR--YRQAAKTELRVLQTIKENDR 345
R+ + +G+G +G V D +N + VA+K I + Y Q E+++L + +
Sbjct: 24 RYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENI 83
Query: 346 SGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQLVRSVCF 405
G ++ + + +V DL +Y + H+ Q++R + +
Sbjct: 84 IG-INDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQ---HLSNDHICYFLYQILRGLKY 139
Query: 406 LHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKLID 465
+H ++H DLKP N+L+ + TC ++K+ D
Sbjct: 140 IHSANVLHRDLKPSNLLL-NTTC-------------------------------DLKICD 167
Query: 466 FGSAVFYNEYH------PPVVSTRHYRAPEIVL-GLGWSFPCDIWSIACVLVELVTGESL 518
FG A + H V+TR YRAPEI+L G++ DIWS+ C+L E+++ +
Sbjct: 168 FGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPI 227
Query: 519 YP 520
+P
Sbjct: 228 FP 229
>Hs20986529 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 80.5 bits (197), Expect = 8e-15
Identities = 58/242 (23%), Positives = 105/242 (42%), Gaps = 45/242 (18%)
Query: 288 RFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDR--YRQAAKTELRVLQTIKENDR 345
R+ + +G+G +G V D +N + VA+K I + Y Q E+++L + +
Sbjct: 24 RYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENI 83
Query: 346 SGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQLVRSVCF 405
G ++ + + +V DL +Y + H+ Q++R + +
Sbjct: 84 IG-INDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQ---HLSNDHICYFLYQILRGLKY 139
Query: 406 LHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKLID 465
+H ++H DLKP N+L+ + TC ++K+ D
Sbjct: 140 IHSANVLHRDLKPSNLLL-NTTC-------------------------------DLKICD 167
Query: 466 FGSAVFYNEYH------PPVVSTRHYRAPEIVL-GLGWSFPCDIWSIACVLVELVTGESL 518
FG A + H V+TR YRAPEI+L G++ DIWS+ C+L E+++ +
Sbjct: 168 FGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPI 227
Query: 519 YP 520
+P
Sbjct: 228 FP 229
>CE29318 [T] KOG0660 Mitogen-activated protein kinase
Length = 474
Score = 80.5 bits (197), Expect = 8e-15
Identities = 73/282 (25%), Positives = 128/282 (44%), Gaps = 54/282 (19%)
Query: 291 AMQLLGQGTFGKVVK----CKDYLNDITVAVKIIRAV---DRYRQAAKTELRVLQTIKEN 343
+++ LG G+FG V+K C+D L VA+K +R + + E ++LQ ++ +
Sbjct: 120 SIEYLGGGSFGNVIKTSAVCRDGLRRY-VAIKKMREPFFDPHHARRIFRETKLLQLMRHD 178
Query: 344 DRSGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNN---GYARFPGSHVQAIGKQLV 400
+ E D+++ + +VT+ GRS+Y + G H++ I Q++
Sbjct: 179 NIICALDIYTPDEENDFRD-VYVVTEFAGRSLYQILKQQRDYGRRVLTDEHIKFIIYQII 237
Query: 401 RSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPE 460
R++ ++H IIH DLKP N+ + D++ +
Sbjct: 238 RALKYIHSANIIHRDLKPGNLALTDDS--------------------------------D 265
Query: 461 VKLIDFGSAVFYNEYHPPV---VSTRHYRAPEIVLGLGWSFP--CDIWSIACVLVELVTG 515
+ ++DFG A + + V TR YR+PE++ S+ D+WS+ C+ EL+TG
Sbjct: 266 LMILDFGLARSLEKKDTSLTQYVQTRWYRSPEVIYWKIDSYTNLADMWSLGCIAAELLTG 325
Query: 516 ESLYPIHENTEHMAMMQRINNEKFPKKMVEKMFFKVENKYGS 557
E L+P E A QRI + E++ K+EN S
Sbjct: 326 EPLFP---GDEPNAQYQRIT--QLCGSPDEELLTKIENDNSS 362
>At1g50230 [R] KOG0597 Serine-threonine protein kinase FUSED
Length = 269
Score = 80.5 bits (197), Expect = 8e-15
Identities = 69/263 (26%), Positives = 122/263 (46%), Gaps = 51/263 (19%)
Query: 289 FQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRA---VDRYRQAAKTELRVLQTIKENDR 345
+ ++L+G+G+FG+V K + TVA+K I D+ + + E+ +L+ +K +
Sbjct: 6 YHVIELVGEGSFGRVYKGRRKYTGQTVAMKFIMKQGKTDKDIHSLRQEIEILRKLKHEN- 64
Query: 346 SGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQLVRSVCF 405
+ + + F+ C+VT+ +++ + ++ P VQAI KQLV+++ +
Sbjct: 65 -----IIEMLDSFENAREFCVVTEFAQGELFEILEDDKC--LPEEQVQAIAKQLVKALDY 117
Query: 406 LHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKLID 465
LH IIH D+KP+NILI G + VKL D
Sbjct: 118 LHSNRIIHRDMKPQNILI---------------------------GAGSV-----VKLCD 145
Query: 466 FGSAVFYNE---YHPPVVSTRHYRAPEIVLGLGWSFPCDIWSIACVLVELVTGESLYPIH 522
FG A + + T Y APE+V + D+WS+ +L EL G+ P +
Sbjct: 146 FGFARAMSTNTVVLRSIKGTPLYMAPELVKEQPYDRTVDLWSLGVILYELYVGQP--PFY 203
Query: 523 ENTEHMAMMQRINNE--KFPKKM 543
N+ + A+++ I + K+P +M
Sbjct: 204 TNSVY-ALIRHIVKDPVKYPDEM 225
>7300773 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 302
Score = 80.5 bits (197), Expect = 8e-15
Identities = 66/264 (25%), Positives = 116/264 (43%), Gaps = 58/264 (21%)
Query: 284 FAKNRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKEN 343
+A +R++ ++ +G+G G V K D + VA+K + +++ A LR ++T++
Sbjct: 4 YAPSRYKMLEKIGEGVHGCVFKAIDLQRNKEVAIKKVALKNKFGNIALNTLREIKTLQ-- 61
Query: 344 DRSGQYQCLLLREFFDYKNHICLVTDLYGRS-VYDFMTNNGYARFPGS-------HVQAI 395
L E+ + I + DL G S V ++ + Y R V+
Sbjct: 62 --------LCKSEYI--LDIIDIYPDLTGLSLVLEYQPDTLYNRLKSEVNPLSRQQVRKF 111
Query: 396 GKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKI 455
Q+ + + +LH+ G++H D+KP N+LI D
Sbjct: 112 AHQMFKGIAYLHEAGLMHRDIKPANLLISD------------------------------ 141
Query: 456 LINPEVKLIDFGSAVFY-----NEYHPPVVSTRHYRAPEIVLG-LGWSFPCDIWSIACVL 509
+K+ DFG A Y + + P VSTR YRAPEI+ G + D+W+ CV+
Sbjct: 142 --TDMLKIADFGLARLYFPEDESRLYSPQVSTRWYRAPEILFGSQKYGTGVDMWAAGCVV 199
Query: 510 VELVTGESLYPIHENTEHMAMMQR 533
E++ G L+ + E +A++ R
Sbjct: 200 AEMLRGVPLFAGTTDIEQLAIIIR 223
>7290342 [G] KOG0658 Glycogen synthase kinase-3
Length = 1008
Score = 80.5 bits (197), Expect = 8e-15
Identities = 63/240 (26%), Positives = 110/240 (45%), Gaps = 53/240 (22%)
Query: 293 QLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKENDRSGQYQCL 352
+++G G+FG V + K VA+K + R++ R LQ +++ + + L
Sbjct: 552 KVIGNGSFGVVFQAKLCDTGELVAIKKVLQDRRFKN------RELQIMRKLEHCNIVKLL 605
Query: 353 LLREFFDYKN-------HICLVTDLYGRSVYDFMTNNGYAR--FPGSHVQAIGKQLVRSV 403
+F Y + + LV + +VY + P + ++ QL RS+
Sbjct: 606 ----YFFYSSGEKRDEVFLNLVLEYIPETVYKVARQYAKTKQTIPINFIRLYMYQLFRSL 661
Query: 404 CFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKL 463
++H LGI H D+KP+N+L+ ET V +KL
Sbjct: 662 AYIHSLGICHRDIKPQNLLLDPETAV-------------------------------LKL 690
Query: 464 IDFGSA--VFYNEYHPPVVSTRHYRAPEIVLG-LGWSFPCDIWSIACVLVELVTGESLYP 520
DFGSA + + E + + +R+YRAPE++ G + ++ D+WS CVL EL+ G+ ++P
Sbjct: 691 CDFGSAKQLLHGEPNVSYICSRYYRAPELIFGAINYTTKIDVWSAGCVLAELLLGQPIFP 750
>Hs4826684_1 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 370
Score = 80.5 bits (197), Expect = 8e-15
Identities = 85/334 (25%), Positives = 134/334 (39%), Gaps = 57/334 (17%)
Query: 295 LGQGTFGKVVKCKDYLNDITVAVKII---RAVDRYRQAAKTEL-RVLQTIKENDRSGQYQ 350
LG G F V KC++ + A K I R R ++ ++ R + +KE
Sbjct: 19 LGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRRGVSREDIEREVSILKEIQHPN--- 75
Query: 351 CLLLREFFDYKNHICLVTDLY-GRSVYDFMTNNGYARFPGSHVQAIGKQLVRSVCFLHDL 409
+ L E ++ K + L+ +L G ++DF+ KQ++ V +LH L
Sbjct: 76 VITLHEVYENKTDVILILELVAGGELFDFLAEK--ESLTEEEATEFLKQILNGVYYLHSL 133
Query: 410 GIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKLIDFGSA 469
I H DLKPENI++ D +++P P +K+IDFG A
Sbjct: 134 QIAHFDLKPENIMLLD-----RNVP-----------------------KPRIKIIDFGLA 165
Query: 470 ---VFYNEYHPPVVSTRHYRAPEIVLGLGWSFPCDIWSIACVLVELVTGESLYPIHENTE 526
F NE+ + T + APEIV D+WSI + L++G S + E
Sbjct: 166 HKIDFGNEF-KNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGDTKQE 224
Query: 527 HMAMMQRINNE----------KFPKKMVEKMFFKVENKYGSIPTDLQTSVVKYFDRQTGE 576
+A + +N E K + ++ K K +I LQ +K D Q
Sbjct: 225 TLANVSAVNYEFEDEYFSNTSALAKDFIRRLLVKDPKKRMTIQDSLQHPWIKPKDTQQAL 284
Query: 577 LR--WPLRNSKGQVITKEKSWK---RILATCDRL 605
R + K + K WK R+++ C RL
Sbjct: 285 SRKASAVNMEKFKKFAARKKWKQSVRLISLCQRL 318
>Hs4759052 [T] KOG0603 Ribosomal protein S6 kinase
Length = 809
Score = 80.1 bits (196), Expect = 1e-14
Identities = 70/271 (25%), Positives = 121/271 (43%), Gaps = 53/271 (19%)
Query: 278 YQENDIFAKNRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKII-RAVDRYRQAAKTELRV 336
YQ D+ K++ LG+G+F KC ++ + VKII + ++ Q T L++
Sbjct: 420 YQHYDLDLKDK-----PLGEGSFSICRKCVHKKSNQALQVKIISKRMEANTQKEITALKL 474
Query: 337 LQTIKENDRSGQYQCLLLREFFDYKNHICLVTDLY-GRSVYDFMTNNGYARFPGSHVQAI 395
+ G + L E F + H LV +L G ++D + + F + I
Sbjct: 475 CE--------GHPNIVKLHEVFHDQLHTFLVMELLNGGELFDALRKKKH--FSETEASYI 524
Query: 396 GKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKI 455
++LV ++ +HDLG++H DLKPEN+L DE
Sbjct: 525 MRKLVSALSHMHDLGVVHRDLKPENLLFTDEN---------------------------- 556
Query: 456 LINPEVKLIDFGSAVFYNEYHPPVVS---TRHYRAPEIVLGLGWSFPCDIWSIACVLVEL 512
N E+K+IDFG A + P+ + T H PE++ G+ CD+WS+ +L +
Sbjct: 557 -DNLEIKIIDFGFARLKPPDNQPLKTPCFTLHSCRPELLNQNGYDESCDLWSLGVILYTM 615
Query: 513 VTGESLYPIHEN----TEHMAMMQRINNEKF 539
++G+ + H+ T + +M++I F
Sbjct: 616 LSGQVPFQSHDRSLTCTSAVEIMKKIKKGDF 646
>Hs4502743 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 346
Score = 80.1 bits (196), Expect = 1e-14
Identities = 66/236 (27%), Positives = 107/236 (44%), Gaps = 49/236 (20%)
Query: 288 RFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIR------AVDRYRQAAKTELRVLQTIK 341
R++ + LG+G F V K +D + VA+K I+ A D + A E+++LQ +
Sbjct: 11 RYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELS 70
Query: 342 ENDRSGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQLVR 401
+ G L + F +K++I LV D + + +N P SH++A ++
Sbjct: 71 HPNIIG------LLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTP-SHIKAYMLMTLQ 123
Query: 402 SVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEV 461
+ +LH I+H DLKP N+L+ DE N +
Sbjct: 124 GLEYLHQHWILHRDLKPNNLLL-DE-------------------------------NGVL 151
Query: 462 KLIDFGSAVFY---NEYHPPVVSTRHYRAPEIVLGLG-WSFPCDIWSIACVLVELV 513
KL DFG A + N + V TR YRAPE++ G + D+W++ C+L EL+
Sbjct: 152 KLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELL 207
>Hs4557439 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 305
Score = 79.7 bits (195), Expect = 1e-14
Identities = 65/236 (27%), Positives = 106/236 (44%), Gaps = 39/236 (16%)
Query: 289 FQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKENDRSGQ 348
FQ ++ +G+GT+G V K K+ VA+K IR T +R + +KE
Sbjct: 4 FQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKHPNI 63
Query: 349 YQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQLVRSVCFLHD 408
+ L + + + LV + + + +M + + P +++ QL++ V F H
Sbjct: 64 VRLL---DVVHNERKLYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQLLQGVSFCHS 120
Query: 409 LGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKLIDFGS 468
+IH DLKP+N+LI +L + +KL DFG
Sbjct: 121 HRVIHRDLKPQNLLI---------------------NELGA-----------IKLADFGL 148
Query: 469 AVFYN---EYHPPVVSTRHYRAPEIVLGLG-WSFPCDIWSIACVLVELVTGESLYP 520
A + + V T YRAPEI+LG ++ DIWSI C+ E+VT ++L+P
Sbjct: 149 ARAFGVPLRTYTHEVVTLWYRAPEILLGSKFYTTAVDIWSIGCIFAEMVTRKALFP 204
>CE27415 [T] KOG0671 LAMMER dual specificity kinases
Length = 302
Score = 79.7 bits (195), Expect = 1e-14
Identities = 62/216 (28%), Positives = 99/216 (45%), Gaps = 39/216 (18%)
Query: 364 ICLVTDLYGRSVYDFMTNNGYARFPGSHV-------QAIGKQLVRSVCFLHDLGIIHTDL 416
I + +L GRSV++ M + GS + + +GKQL+ ++ L + I+H DL
Sbjct: 32 IAISFELKGRSVFEVMDSTKGKMPAGSEISFEINAIRVMGKQLLEAMEKLESVKIVHLDL 91
Query: 417 KPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPE---VKLIDFGSAVFYN 473
KPENI + ++ + I P V ++DFG+A
Sbjct: 92 KPENICFFSSCIFKTTVTGNVC-----------------FIQPSTFHVCVVDFGNARTIR 134
Query: 474 EYHPP---VVSTRHYRAPEIVLGLGWSFPCDIWSIACVLVELVTGESLYPIHENTE---- 526
+ PP +V T++YRAPEI LGL +S DIWS C+L EL TG+ L+ + ++
Sbjct: 135 QDKPPKYALVQTQNYRAPEIFLGLPFSVKSDIWSFGCILSELYTGDLLFYGNSKSDTEEL 194
Query: 527 -----HMAMMQRINNEKFPKKMVEKMFFKVENKYGS 557
M + Q ++ PKK + +F + S
Sbjct: 195 QFELMQMIVQQPLSCAMKPKKSSKYIFIVNTENFAS 230
>CE17305 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 375
Score = 79.7 bits (195), Expect = 1e-14
Identities = 66/241 (27%), Positives = 113/241 (46%), Gaps = 46/241 (19%)
Query: 288 RFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELR---VLQTIKEND 344
R+ ++ L G G VV D + VA+K ++ +A+ R +L T+K +
Sbjct: 28 RYVNLKFLNVGAQGIVVMADDLVTTQRVAIKKMQQPFLLTMSARRAYREFILLTTLKHPN 87
Query: 345 RSGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYA-----RFPGSHVQAIGKQL 399
+ L F + ++Y V +FMT+N + R + + Q
Sbjct: 88 ------IIRLLNAFTPDTSLSSFQEVY--LVMEFMTHNLHEVIHRLRLDHETLSFLVYQS 139
Query: 400 VRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINP 459
+ ++ LH+LG IH DLKP NI++ +E CV ++++D RR+ N
Sbjct: 140 LCAIKHLHNLGFIHRDLKPSNIVV-NERCV-----LKVLDFGLARRR-----------NV 182
Query: 460 EVKLIDFGSAVFYNEYHPPVVSTRHYRAPEIVLGLGWSFPCDIWSIACVLVELVTGESLY 519
++++ D+ V TR+YRAPE++LGL +S DIWS+ C+L E++ L+
Sbjct: 183 DMRMSDY-------------VGTRYYRAPEVILGLNYSEKVDIWSVGCILAEMINHTVLF 229
Query: 520 P 520
P
Sbjct: 230 P 230
>CE05507 [T] KOG0603 Ribosomal protein S6 kinase
Length = 785
Score = 79.7 bits (195), Expect = 1e-14
Identities = 79/280 (28%), Positives = 128/280 (45%), Gaps = 29/280 (10%)
Query: 272 EEGHYVYQENDIFAKNRFQAMQ--LLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQA 329
E+ + + + FAK + LLG+G F V +C+ ++ AVKI+ ++
Sbjct: 363 EDVNALLASSSFFAKYKLDKSDAGLLGKGAFSVVRRCERVVDGAQFAVKIVS--QKFASQ 420
Query: 330 AKTELRVLQTIKENDRSGQYQCLLLREFFDYKNHICLVTD-LYGRSVYDFMTNNGYARFP 388
A+ E R+L+ ++ G + L + H LV + L G + + + RF
Sbjct: 421 AQREARILEMVQ-----GHPNIVQLHDVHSDPLHFYLVMEILTGNELLERIRK--LERFT 473
Query: 389 GSHVQAIGKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLA 448
S I +QLV +V +LHD I+H DLKPENIL ++ S + ++D R L
Sbjct: 474 ESEAADIMRQLVSAVKYLHDKRIVHRDLKPENILF---ESIDSSARLRLVDFGFAR--LL 528
Query: 449 SGGKRKILINPEVKLIDFGSAVFYNEYHPPV-VSTRHYRAPEIVLGLGWSFP-----CDI 502
+ L + +V +G + H T Y APE VL +G S P CD+
Sbjct: 529 PNSMEQQLKSVQVLRKMYGLIAHNHSLHSETPCFTLQYAAPE-VLDVGDSQPEYNEQCDL 587
Query: 503 WSIACVLVELVTGESLYPIHENTEHMA---MMQRINNEKF 539
WS+ VL +++G+ P H + + +MQRI +F
Sbjct: 588 WSLGVVLFTMLSGQ--VPFHARSRQESATEIMQRICRAEF 625
>At3g04530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 277
Score = 79.7 bits (195), Expect = 1e-14
Identities = 73/296 (24%), Positives = 133/296 (44%), Gaps = 60/296 (20%)
Query: 286 KNRFQAMQLLGQGTFGKVVKC-----KDYLNDITVAVKI-IRAVDRYRQAAKTELRVLQT 339
+N +Q +G+G FG + +C K++ T+ ++ I A+DR + +TE R++
Sbjct: 8 ENNYQLCDEIGRGRFGTITRCFSPATKEFYACKTIDKRVLIDALDR--ECIETEPRIMAM 65
Query: 340 IKENDRSGQYQCLLLREFFDYKNHICLVTDLYG--RSVYDFMTNNGYARFPGSHVQAIGK 397
+ + + + + ++ ++ + +V +L ++YD + + G R S + K
Sbjct: 66 LPPHPN-----IIRIFDLYETEDSLAIVMELVDPPMTIYDRLISAG-GRLSESESASYAK 119
Query: 398 QLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILI 457
Q++ ++ H ++H D+KP+N+L+ L SGG
Sbjct: 120 QILSALAHCHRCDVVHRDVKPDNVLV----------------------DLVSGG------ 151
Query: 458 NPEVKLIDFGSAVFYN-EYHPPVVSTRHYRAPEIVLGLGWSFPCDIWSIACVLVELVTGE 516
VKL DFGSAV+ E VV T +Y APE+V+G + DIWS V+ ++ GE
Sbjct: 152 ---VKLCDFGSAVWLGGETAEGVVGTPYYVAPEVVMGRKYDEKVDIWSAGVVIYTMLAGE 208
Query: 517 SLYPIHENTEHMAMMQRINNEKFPKKMVEKMFFKVENKYGSIPTDLQTSVVKYFDR 572
+ E E + N +FP K K+GS+ ++ + + K R
Sbjct: 209 PPFN-GETAEDIFESILRGNLRFPPK-----------KFGSVSSEAKDLLRKMICR 252
>At1g06390 [G] KOG0658 Glycogen synthase kinase-3
Length = 407
Score = 79.7 bits (195), Expect = 1e-14
Identities = 70/297 (23%), Positives = 132/297 (43%), Gaps = 46/297 (15%)
Query: 249 LKKSPLLGSHQDKLRSMDRFKTDEEGHYVYQENDIFAKN-------RFQAMQLLGQGTFG 301
LK+ P L S ++ ++ GH + I KN + A +++G G+FG
Sbjct: 25 LKRRPELDSDKEMSAAVIEGNDAVTGHII--STTIGGKNGEPKQTISYMAERVVGTGSFG 82
Query: 302 KVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKENDRSGQYQCLLLREFFDYK 361
V + K +VA+K + RY+ EL++++ + + C D +
Sbjct: 83 IVFQAKCLETGESVAIKKVLQDRRYKNR---ELQLMRPMDHPNVISLKHCFFSTTSRD-E 138
Query: 362 NHICLVTDLYGRSVYDFMTN--NGYARFPGSHVQAIGKQLVRSVCFLHDL-GIIHTDLKP 418
+ LV + ++Y + + + R P +V+ Q+ R + ++H + G+ H D+KP
Sbjct: 139 LFLNLVMEYVPETLYRVLRHYTSSNQRMPIFYVKLYTYQIFRGLAYIHTVPGVCHRDVKP 198
Query: 419 ENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKLIDFGSAVFYNEYHPP 478
+N+L+ D LT + KL G K+L+ E +
Sbjct: 199 QNLLV---------------DPLTHQVKLCDFGSAKVLVKGEPNI--------------S 229
Query: 479 VVSTRHYRAPEIVLGLG-WSFPCDIWSIACVLVELVTGESLYPIHENTEHMAMMQRI 534
+ +R+YRAPE++ G ++ DIWS CVL EL+ G+ L+P + + + + ++
Sbjct: 230 YICSRYYRAPELIFGATEYTASIDIWSAGCVLAELLLGQPLFPGENSVDQLVEIIKV 286
>HsM20070143 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 424
Score = 79.3 bits (194), Expect = 2e-14
Identities = 79/306 (25%), Positives = 127/306 (40%), Gaps = 59/306 (19%)
Query: 265 MDRFKTDEEGHYVYQENDIFAK-NRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAV 323
M K D + + V + F R+Q ++ +G G G V D + I VAVK +
Sbjct: 1 MSDSKCDSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRP 60
Query: 324 DRYRQAAKTELRVLQTIKENDRSGQYQCL-------LLREFFDYKNHICLVTDLYGRSVY 376
+ + AK R L +K + L L EF D + LV +L ++
Sbjct: 61 FQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQD----VYLVMELMDANLC 116
Query: 377 DFMTNNGYARFPGSHVQAIGKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPME 436
+ + + + Q++ + LH GIIH DLKP NI++ + +
Sbjct: 117 QVI----HMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTL------- 165
Query: 437 IIDSLTERRKLASGGKRKILINPEVKLIDFGSA--VFYNEYHPPVVSTRHYRAPEIVLGL 494
K++DFG A N P V TR+YRAPE++LG+
Sbjct: 166 -------------------------KILDFGLARTACTNFMMTPYVVTRYYRAPEVILGM 200
Query: 495 GWSFPCDIWSIACVLVELVTGESLYPIHENTEHMAMMQRINNE------KFPKKMVEKMF 548
G+ DIWS+ C++ ELV G I + T+H+ ++ + +F KK+ +
Sbjct: 201 GYKENVDIWSVGCIMGELVKG---CVIFQGTDHIDQWNKVIEQLGTPSAEFMKKLQPTVR 257
Query: 549 FKVENK 554
VEN+
Sbjct: 258 NYVENR 263
>Hs4505569 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 493
Score = 79.3 bits (194), Expect = 2e-14
Identities = 64/241 (26%), Positives = 106/241 (43%), Gaps = 48/241 (19%)
Query: 288 RFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKENDRSG 347
+++ + L+G+G++G V+KC++ VA+K D + K +R ++ +K+
Sbjct: 3 KYENLGLVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHEN 62
Query: 348 QYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFP-GSHVQAIGK---QLVRSV 403
L E K LV + ++ D + FP G Q + K Q++ +
Sbjct: 63 LVNLL---EVCKKKKRWYLVFEFVDHTILDDLE-----LFPNGLDYQVVQKYLFQIINGI 114
Query: 404 CFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKL 463
F H IIH D+KPENIL+ + VKL
Sbjct: 115 GFCHSHNIIHRDIKPENILVSQ--------------------------------SGVVKL 142
Query: 464 IDFGSA---VFYNEYHPPVVSTRHYRAPEIVLG-LGWSFPCDIWSIACVLVELVTGESLY 519
DFG A E + V+TR YRAPE+++G + + D+W+I C++ E+ GE L+
Sbjct: 143 CDFGFARTLAAPGEVYTDYVATRWYRAPELLVGDVKYGKAVDVWAIGCLVTEMFMGEPLF 202
Query: 520 P 520
P
Sbjct: 203 P 203
>Hs21237739 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 382
Score = 79.3 bits (194), Expect = 2e-14
Identities = 79/306 (25%), Positives = 127/306 (40%), Gaps = 59/306 (19%)
Query: 265 MDRFKTDEEGHYVYQENDIFAK-NRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAV 323
M K D + + V + F R+Q ++ +G G G V D + I VAVK +
Sbjct: 1 MSDSKCDSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRP 60
Query: 324 DRYRQAAKTELRVLQTIKENDRSGQYQCL-------LLREFFDYKNHICLVTDLYGRSVY 376
+ + AK R L +K + L L EF D + LV +L ++
Sbjct: 61 FQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQD----VYLVMELMDANLC 116
Query: 377 DFMTNNGYARFPGSHVQAIGKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPME 436
+ + + + Q++ + LH GIIH DLKP NI++ + +
Sbjct: 117 QVI----HMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTL------- 165
Query: 437 IIDSLTERRKLASGGKRKILINPEVKLIDFGSA--VFYNEYHPPVVSTRHYRAPEIVLGL 494
K++DFG A N P V TR+YRAPE++LG+
Sbjct: 166 -------------------------KILDFGLARTACTNFMMTPYVVTRYYRAPEVILGM 200
Query: 495 GWSFPCDIWSIACVLVELVTGESLYPIHENTEHMAMMQRINNE------KFPKKMVEKMF 548
G+ DIWS+ C++ ELV G I + T+H+ ++ + +F KK+ +
Sbjct: 201 GYKENVDIWSVGCIMGELVKG---CVIFQGTDHIDQWNKVIEQLGTPSAEFMKKLQPTVR 257
Query: 549 FKVENK 554
VEN+
Sbjct: 258 NYVENR 263
>Hs21237736 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 424
Score = 79.3 bits (194), Expect = 2e-14
Identities = 79/306 (25%), Positives = 127/306 (40%), Gaps = 59/306 (19%)
Query: 265 MDRFKTDEEGHYVYQENDIFAK-NRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAV 323
M K D + + V + F R+Q ++ +G G G V D + I VAVK +
Sbjct: 1 MSDSKCDSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRP 60
Query: 324 DRYRQAAKTELRVLQTIKENDRSGQYQCL-------LLREFFDYKNHICLVTDLYGRSVY 376
+ + AK R L +K + L L EF D + LV +L ++
Sbjct: 61 FQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQD----VYLVMELMDANLC 116
Query: 377 DFMTNNGYARFPGSHVQAIGKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPME 436
+ + + + Q++ + LH GIIH DLKP NI++ + +
Sbjct: 117 QVI----HMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTL------- 165
Query: 437 IIDSLTERRKLASGGKRKILINPEVKLIDFGSA--VFYNEYHPPVVSTRHYRAPEIVLGL 494
K++DFG A N P V TR+YRAPE++LG+
Sbjct: 166 -------------------------KILDFGLARTACTNFMMTPYVVTRYYRAPEVILGM 200
Query: 495 GWSFPCDIWSIACVLVELVTGESLYPIHENTEHMAMMQRINNE------KFPKKMVEKMF 548
G+ DIWS+ C++ ELV G I + T+H+ ++ + +F KK+ +
Sbjct: 201 GYKENVDIWSVGCIMGELVKG---CVIFQGTDHIDQWNKVIEQLGTPSAEFMKKLQPTVR 257
Query: 549 FKVENK 554
VEN+
Sbjct: 258 NYVENR 263
>At5g22840 [T] KOG1290 Serine/threonine protein kinase
Length = 538
Score = 79.3 bits (194), Expect = 2e-14
Identities = 48/156 (30%), Positives = 79/156 (49%), Gaps = 5/156 (3%)
Query: 274 GHYVYQENDIFAKNRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTE 333
G++ + D F + LG G F V D LN VA+KI ++ Y +AA E
Sbjct: 30 GYHTVRVGDTFKNGSYVIQSKLGWGHFSTVWLAWDTLNSRYVALKIQKSAQHYTEAAMDE 89
Query: 334 LRVLQTIKENDRSGQYQCLLLREFFDYKN----HICLVTDLYGRSVYDFMTNNGYARFPG 389
+++L+ I E D + + L + F + H+C+V + G ++ + + Y P
Sbjct: 90 IKILKQIAEGDAEDKKCVVKLLDHFKHAGPNGQHVCMVFEYLGDNLLSVIKYSDYRGVPL 149
Query: 390 SHVQAIGKQLVRSVCFLH-DLGIIHTDLKPENILIC 424
V+ I ++ + +LH +L IIHTD+KPENIL+C
Sbjct: 150 HMVKEICFHILVGLDYLHRELSIIHTDIKPENILLC 185
Score = 65.9 bits (159), Expect = 2e-10
Identities = 36/98 (36%), Positives = 58/98 (58%), Gaps = 8/98 (8%)
Query: 445 RKLASGGKRKIL--INPEVKLIDFGSAVFYNEYHPPVVSTRHYRAPEIVLGLGWSFPCDI 502
R+ + ++K+L ++ + KL+DFG+A + + + TR YR PE+VLG +S D+
Sbjct: 292 RRGSQSTRQKLLADVDRKCKLVDFGNACWTYKQFTSDIQTRQYRCPEVVLGSKYSTSADM 351
Query: 503 WSIACVLVELVTGESLYPIH--ENTE----HMAMMQRI 534
WS AC+ EL TG+ L+ H EN E H+A+M +
Sbjct: 352 WSFACICFELATGDVLFDPHSGENFERDEDHLALMMEL 389
>At3g18040 [T] KOG0660 Mitogen-activated protein kinase
Length = 613
Score = 79.3 bits (194), Expect = 2e-14
Identities = 75/272 (27%), Positives = 123/272 (44%), Gaps = 52/272 (19%)
Query: 287 NRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKT---ELRVLQTIKEN 343
+R+Q +++G+G++G V D + VA+K I V + A E+++L+ ++
Sbjct: 124 SRYQIQEVIGKGSYGVVASAIDTHSGEKVAIKKINDVFEHVSDATRILREIKLLRLLRHP 183
Query: 344 DRSGQYQCLL---LREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQLV 400
D +L REF D I +V +L ++ + N H Q QL+
Sbjct: 184 DIVEIKHVMLPPSRREFRD----IYVVFELMESDLHQVIKAND--DLTPEHYQFFLYQLL 237
Query: 401 RSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPE 460
R + F+H + H DLKP+NIL + C + K+ G ++ N
Sbjct: 238 RGLKFIHTANVFHRDLKPKNIL-ANSDC---------------KLKICDFGLARVSFN-- 279
Query: 461 VKLIDFGSAVFYNEYHPPVVSTRHYRAPEIVLGL--GWSFPCDIWSIACVLVELVTGESL 518
D SA+F+ +Y V+TR YRAPE+ ++ DIWSI C+ E++TG+ L
Sbjct: 280 ----DAPSAIFWTDY----VATRWYRAPELCGSFFSKYTPAIDIWSIGCIFAEMLTGKPL 331
Query: 519 YP----IHE--------NTEHMAMMQRINNEK 538
+P +H+ T + RI NEK
Sbjct: 332 FPGKNVVHQLDIMTDLLGTPPPEAIARIRNEK 363
>At3g48750 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 294
Score = 79.0 bits (193), Expect = 2e-14
Identities = 64/251 (25%), Positives = 112/251 (44%), Gaps = 36/251 (14%)
Query: 287 NRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKENDRS 346
++++ ++ +G+GT+G V K +D + + T+A+K IR T +R + +KE S
Sbjct: 2 DQYEKVEKIGEGTYGVVYKARDKVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQHS 61
Query: 347 GQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQLVRSVCFL 406
+ + + + LV + + M + ++ Q++R + +
Sbjct: 62 ---NIVKYDDVVHSEKRLYLVFEYLDLDLKKHMDSTPDFSKDLHMIKTYLYQILRGIAYC 118
Query: 407 HDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKLIDF 466
H ++H DLKP+N+L ID T KLA G + F
Sbjct: 119 HSHRVLHRDLKPQNLL---------------IDRRTNSLKLADFGLARA----------F 153
Query: 467 GSAV--FYNEYHPPVVSTRHYRAPEIVLGL-GWSFPCDIWSIACVLVELVTGESLYPIHE 523
G V F +E V T YRAPEI+LG +S P DIWS+ C+ E+++ + L+P
Sbjct: 154 GIPVRTFTHE-----VVTLWYRAPEILLGSHHYSTPVDIWSVGCIFAEMISQKPLFPGDS 208
Query: 524 NTEHMAMMQRI 534
+ + + RI
Sbjct: 209 EIDQLFKIFRI 219
>At3g05840 [G] KOG0658 Glycogen synthase kinase-3
Length = 409
Score = 79.0 bits (193), Expect = 2e-14
Identities = 63/252 (25%), Positives = 115/252 (45%), Gaps = 41/252 (16%)
Query: 289 FQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKENDRSGQ 348
+ A +++G G+FG V + K TVA+K + RY+ EL+ ++ + +
Sbjct: 73 YMAERVVGHGSFGVVFQAKCLETGETVAIKKVLQDRRYK---NRELQTMRLLDHPNVVSL 129
Query: 349 YQCLLLREFFDYKNHICLVTDLYGRSVYDFMT--NNGYARFPGSHVQAIGKQLVRSVCFL 406
C D + ++ LV + +V+ + N R P +V+ Q+ RS+ ++
Sbjct: 130 KHCFFSTTEKD-ELYLNLVLEYVPETVHRVIKHYNKLNQRMPLVYVKLYTYQIFRSLSYI 188
Query: 407 HD-LGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKLID 465
H +G+ H D+KP+N+L+ T +VKL D
Sbjct: 189 HRCIGVCHRDIKPQNLLVNPHT-------------------------------HQVKLCD 217
Query: 466 FGSAVFYNEYHPPV--VSTRHYRAPEIVLG-LGWSFPCDIWSIACVLVELVTGESLYPIH 522
FGSA + P + + +R+YRAPE++ G ++ D+WS CVL EL+ G+ L+P
Sbjct: 218 FGSAKVLVKGEPNISYICSRYYRAPELIFGATEYTTAIDVWSAGCVLAELLLGQPLFPGE 277
Query: 523 ENTEHMAMMQRI 534
+ + + ++
Sbjct: 278 SGVDQLVEIIKV 289
>At2g42880 [T] KOG0660 Mitogen-activated protein kinase
Length = 594
Score = 79.0 bits (193), Expect = 2e-14
Identities = 69/269 (25%), Positives = 125/269 (45%), Gaps = 46/269 (17%)
Query: 287 NRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAV-DRYRQAAKT--ELRVLQTIKEN 343
NRF+ +++G+G++G V D L VA+K I + + AA+ E+++L+ ++
Sbjct: 11 NRFKVQEVIGKGSYGVVCSAIDTLTGEKVAIKKIHDIFEHISDAARILREIKLLRLLRHP 70
Query: 344 DRSGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQLVRSV 403
D +L ++K+ I +V +L ++ + N H Q QL+R++
Sbjct: 71 DIVEIKHIMLPPSRREFKD-IYVVFELMESDLHQVIKAND--DLTREHYQFFLYQLLRAL 127
Query: 404 CFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKL 463
++H + H DLKP+NIL + C + K+ G ++ N
Sbjct: 128 KYIHTANVYHRDLKPKNIL-ANANC---------------KLKICDFGLARVAFN----- 166
Query: 464 IDFGSAVFYNEYHPPVVSTRHYRAPEIVLGL--GWSFPCDIWSIACVLVELVTGESLYP- 520
D + +F+ +Y V+TR YRAPE+ ++ DIWSI C+ E++ G+ L+P
Sbjct: 167 -DTPTTIFWTDY----VATRWYRAPELCGSFYSKYTPAIDIWSIGCIFAEVLMGKPLFPG 221
Query: 521 ---IHE--------NTEHMAMMQRINNEK 538
+H+ T + + R+ NEK
Sbjct: 222 KNVVHQLDLMTDLLGTPSLDTISRVRNEK 250
>YMR216c [T] KOG1290 Serine/threonine protein kinase
Length = 742
Score = 78.6 bits (192), Expect = 3e-14
Identities = 48/160 (30%), Positives = 88/160 (55%), Gaps = 10/160 (6%)
Query: 274 GHYVYQENDIFAKNRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTE 333
G++ + + + R+ ++ LG G F V KD +N+ VA+KI+R Y +AA+ E
Sbjct: 143 GYHPAFKGEPYKDARYILVRKLGWGHFSTVWLAKDMVNNTHVAMKIVRGDKVYTEAAEDE 202
Query: 334 LRVLQTIKENDRS-----GQYQCLLLREFFDYKN----HICLVTDLYGRSVYDFMTNNGY 384
+++LQ + + D + G L L + F++K H+ +V ++ G ++ + +
Sbjct: 203 IKLLQRVNDADNTKEDSMGANHILKLLDHFNHKGPNGVHVVMVFEVLGENLLALIKKYEH 262
Query: 385 ARFPGSHVQAIGKQLVRSVCFLH-DLGIIHTDLKPENILI 423
P +V+ I KQL+ + ++H GIIHTD+KPEN+L+
Sbjct: 263 RGIPLIYVKQISKQLLLGLDYMHRRCGIIHTDIKPENVLM 302
Score = 68.2 bits (165), Expect = 4e-11
Identities = 26/60 (43%), Positives = 43/60 (71%)
Query: 460 EVKLIDFGSAVFYNEYHPPVVSTRHYRAPEIVLGLGWSFPCDIWSIACVLVELVTGESLY 519
++K+ D G+A +Y+E++ + TR YR+PE++LG W DIWS AC++ EL+TG+ L+
Sbjct: 545 QIKIADLGNACWYDEHYTNSIQTREYRSPEVLLGAPWGCGADIWSTACLIFELITGDFLF 604
>SPBPI064 [G] KOG0658 Glycogen synthase kinase-3
Length = 350
Score = 78.6 bits (192), Expect = 3e-14
Identities = 52/181 (28%), Positives = 84/181 (45%), Gaps = 40/181 (22%)
Query: 361 KNHICLVTDLYGRSVYDFMTNNGYAR----FPGSHVQAIGKQLVRSVCFLHDLGIIHTDL 416
+ H+CL+ + +V+D M Y R P ++ QL R++ +LH G+ H D+
Sbjct: 63 ETHLCLLLEYMPETVFDDM--RWYTRRRKSIPNLSIKLYAFQLFRALAYLHSTGVCHRDI 120
Query: 417 KPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKLIDFGSAVFYNEYH 476
KP+N+L+ +T + +KL DFGSA
Sbjct: 121 KPQNLLVDYKTGI-------------------------------LKLCDFGSAKVLVPSE 149
Query: 477 PPV--VSTRHYRAPEIVLG-LGWSFPCDIWSIACVLVELVTGESLYPIHENTEHMAMMQR 533
P V + +R+YRAPE+V G ++ D+WS ACV+ EL G L+P + E + + R
Sbjct: 150 PNVSYICSRYYRAPELVFGATHYTTKIDVWSAACVIAELFIGRPLFPGDSSVEQLVEIIR 209
Query: 534 I 534
+
Sbjct: 210 V 210
>Hs22051130 [G] KOG0658 Glycogen synthase kinase-3
Length = 483
Score = 78.6 bits (192), Expect = 3e-14
Identities = 70/290 (24%), Positives = 129/290 (44%), Gaps = 55/290 (18%)
Query: 292 MQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKENDRSGQYQC 351
++++G G+FG V + + VA+K + R++ R LQ +++ D C
Sbjct: 122 IKVIGNGSFGVVYQARLAETRELVAIKKVLQDKRFKN------RELQIMRKLDH-----C 170
Query: 352 LLLR-EFFDYKN-------HICLVTDLYGRSVYDFMTNNGYARF--PGSHVQAIGKQLVR 401
++R +F Y + ++ LV + +VY + A+ P +V+ QL R
Sbjct: 171 NIVRLRYFFYSSGEKKDELYLNLVLEYVPETVYRVARHFTKAKLTIPILYVKVYMYQLFR 230
Query: 402 SVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEV 461
S+ ++H G+ H D+KP+N+L+ +T V +
Sbjct: 231 SLAYIHSQGVCHRDIKPQNLLVDPDTAV-------------------------------L 259
Query: 462 KLIDFGSA--VFYNEYHPPVVSTRHYRAPEIVLG-LGWSFPCDIWSIACVLVELVTGESL 518
KL DFGSA + E + + +R+YRAPE++ G ++ D+WS CVL EL+ G+ +
Sbjct: 260 KLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPI 319
Query: 519 YPIHENTEHMAMMQRINNEKFPKKMVEKMFFKVENKYGSIPTDLQTSVVK 568
+P + + + ++ +++ E E K+ I T V K
Sbjct: 320 FPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWTKVFK 369
>Hs15834624 [T] KOG1290 Serine/threonine protein kinase
Length = 654
Score = 78.6 bits (192), Expect = 3e-14
Identities = 48/181 (26%), Positives = 100/181 (54%), Gaps = 10/181 (5%)
Query: 250 KKSPLLGSHQDKLRSMDRFKTDEEGHYVYQENDIFAKNRFQAMQLLGQGTFGKVVKCKDY 309
++ +LGS D+ + + + G+++ + D+F R+ ++ LG G F V D
Sbjct: 44 QEEEILGSDDDEQEDPNDYC--KGGYHLVKIGDLF-NGRYHVIRKLGWGHFSTVWLSWDI 100
Query: 310 LNDITVAVKIIRAVDRYRQAAKTELRVLQTIKENDRSGQYQCLLLREFFDYK------NH 363
VA+K++++ + Y + A E+R+L++++ +D + + ++++ D+K H
Sbjct: 101 QGKKFVAMKVVKSAEHYTETALDEIRLLKSVRNSDPNDPNREMVVQLLDDFKISGVNGTH 160
Query: 364 ICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQLVRSVCFLH-DLGIIHTDLKPENIL 422
IC+V ++ G + ++ + Y P V+ I +Q+++ + +LH IIHTD+KPENIL
Sbjct: 161 ICMVFEVLGHHLLKWIIKSNYQGLPLPCVKKIIQQVLQGLDYLHTKCRIIHTDIKPENIL 220
Query: 423 I 423
+
Sbjct: 221 L 221
Score = 64.3 bits (155), Expect = 6e-10
Identities = 59/232 (25%), Positives = 89/232 (37%), Gaps = 76/232 (32%)
Query: 460 EVKLIDFGSAVFYNEYHPPVVSTRHYRAPEIVLGLGWSFPCDIWSIACVLVELVTGESLY 519
+VK+ D G+A ++ + + TR YR+ E+++G G++ P DIWS AC+ EL TG+ L+
Sbjct: 492 KVKIADLGNACWHKHFTEDI-QTRQYRSLEVLIGSGYNTPADIWSTACMAFELATGDYLF 550
Query: 520 PIHENTE------HMAMMQRINNEKFPKKMVEKMFFKVENKYGSIPTDLQTSVVKYFDRQ 573
H E H+A++ + K P+K++ V KY K F +
Sbjct: 551 EPHSGEEYTRDEDHIALIIELLG-KVPRKLI------VAGKYS-----------KEFFTK 592
Query: 574 TGELRWPLRNSKGQVITKEKSWKRILATCDRLDVFISKKLQMDYGSWLEIHWDMQLEDNW 633
G+L+ ITK K W +V + K W +
Sbjct: 593 KGDLKH---------ITKLKPW-------GLFEVLVEK-----------YEWSQEEAAG- 624
Query: 634 RLILSKNIDSRNIDKNVFMFWYYFVDLCRKMFEFDPTKRITAKEVIEHEWFN 685
F D M E P KR TA E + H W N
Sbjct: 625 -----------------------FTDFLLPMLELIPEKRATAAECLRHPWLN 653
>Hs11995474 [G] KOG0658 Glycogen synthase kinase-3
Length = 483
Score = 78.6 bits (192), Expect = 3e-14
Identities = 70/290 (24%), Positives = 129/290 (44%), Gaps = 55/290 (18%)
Query: 292 MQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKENDRSGQYQC 351
++++G G+FG V + + VA+K + R++ R LQ +++ D C
Sbjct: 122 IKVIGNGSFGVVYQARLAETRELVAIKKVLQDKRFKN------RELQIMRKLDH-----C 170
Query: 352 LLLR-EFFDYKN-------HICLVTDLYGRSVYDFMTNNGYARF--PGSHVQAIGKQLVR 401
++R +F Y + ++ LV + +VY + A+ P +V+ QL R
Sbjct: 171 NIVRLRYFFYSSGEKKDELYLNLVLEYVPETVYRVARHFTKAKLTIPILYVKVYMYQLFR 230
Query: 402 SVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEV 461
S+ ++H G+ H D+KP+N+L+ +T V +
Sbjct: 231 SLAYIHSQGVCHRDIKPQNLLVDPDTAV-------------------------------L 259
Query: 462 KLIDFGSA--VFYNEYHPPVVSTRHYRAPEIVLG-LGWSFPCDIWSIACVLVELVTGESL 518
KL DFGSA + E + + +R+YRAPE++ G ++ D+WS CVL EL+ G+ +
Sbjct: 260 KLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPI 319
Query: 519 YPIHENTEHMAMMQRINNEKFPKKMVEKMFFKVENKYGSIPTDLQTSVVK 568
+P + + + ++ +++ E E K+ I T V K
Sbjct: 320 FPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWTKVFK 369
>At4g18710 [G] KOG0658 Glycogen synthase kinase-3
Length = 380
Score = 78.6 bits (192), Expect = 3e-14
Identities = 66/238 (27%), Positives = 112/238 (46%), Gaps = 41/238 (17%)
Query: 289 FQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKENDRSGQ 348
+ A +++G G+FG V + K TVA+K + RY+ EL++++ + +
Sbjct: 40 YMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKNR---ELQLMRVMDHPNVVCL 96
Query: 349 YQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYA--RFPGSHVQAIGKQLVRSVCFL 406
C D + + LV + S+Y + + A R P +V+ Q+ R + ++
Sbjct: 97 KHCFFSTTSKD-ELFLNLVMEYVPESLYRVLKHYSSANQRMPLVYVKLYMYQIFRGLAYI 155
Query: 407 HDL-GIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKLID 465
H++ G+ H DLKP+N+L+ D LT +VK+ D
Sbjct: 156 HNVAGVCHRDLKPQNLLV---------------DPLTH----------------QVKICD 184
Query: 466 FGSA--VFYNEYHPPVVSTRHYRAPEIVLGLG-WSFPCDIWSIACVLVELVTGESLYP 520
FGSA + E + + +R YRAPE++ G ++ DIWS CVL EL+ G+ L+P
Sbjct: 185 FGSAKQLVKGEANISYICSRFYRAPELIFGATEYTTSIDIWSAGCVLAELLLGQPLFP 242
>At1g54610 [D] KOG0600 Cdc2-related protein kinase
Length = 572
Score = 78.6 bits (192), Expect = 3e-14
Identities = 67/261 (25%), Positives = 111/261 (41%), Gaps = 59/261 (22%)
Query: 289 FQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKENDR--- 345
F+ + +GQGT+ V K KD L VA+K +R + ++ K R + ++ D
Sbjct: 118 FEKIDKIGQGTYSNVYKAKDMLTGKIVALKKVRFDNLEPESVKFMAREILVLRRLDHPNV 177
Query: 346 -------SGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQ 398
+ + C L F Y +H DL G + ++ +F S V+ + +Q
Sbjct: 178 VKLEGLVTSRMSCSLYL-VFQYMDH-----DLAG------LASSPVVKFSESEVKCLMRQ 225
Query: 399 LVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILIN 458
L+ + H G++H D+K N+LI D GG
Sbjct: 226 LISGLEHCHSRGVLHRDIKGSNLLIDD------------------------GG------- 254
Query: 459 PEVKLIDFGSAVFYNEYHP-PVVS---TRHYRAPEIVLG-LGWSFPCDIWSIACVLVELV 513
+K+ DFG A ++ H P+ S T YRAPE++LG + D+WS C+L EL+
Sbjct: 255 -VLKIADFGLATIFDPNHKRPMTSRVVTLWYRAPELLLGATDYGVGIDLWSAGCILAELL 313
Query: 514 TGESLYPIHENTEHMAMMQRI 534
G + P E + + ++
Sbjct: 314 AGRPIMPGRTEVEQLHKIYKL 334
>CE04172 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 450
Score = 78.2 bits (191), Expect = 4e-14
Identities = 71/288 (24%), Positives = 119/288 (40%), Gaps = 50/288 (17%)
Query: 274 GHYVYQENDIFAKNRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTE 333
G Y ++E D + R+ ++L G + +V +C D D V +K+ +R E
Sbjct: 117 GSYCFKEGDHISY-RYSIDEVLSSGYYAQVFRCTDKKTDKKVCIKL---KNRNLSTTYEE 172
Query: 334 LRVLQTIKENDRSGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQ 393
+L I + +R C+ + ++ ++ H +V + Y + ++ P ++
Sbjct: 173 TIILLRIHQLNRQNNSNCVRMLDYDHFRGHHFIVLENYQTDLASYLCGRSKLT-PREYIP 231
Query: 394 AIGKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKR 453
I K +V + FLH IIH DLKP N+L+ +
Sbjct: 232 MI-KSIVHGLKFLHQNKIIHGDLKPANVLLNEWN-------------------------- 264
Query: 454 KILINPEVKLIDFGSAVFYNEYHPPV---VSTRHYRAPEIVLGLGWSFPCDIWSIACVLV 510
+KL DFG + F N+ P T +Y+APE+ S DIWS+ CV
Sbjct: 265 ----RNNLKLTDFGLSTFVNQ--GPFFRDYQTLYYKAPEVFCQGKVSVEIDIWSLGCVAA 318
Query: 511 ELVTGESLYPIHENTEHMAMMQRINNEKFPKKMVEKMFFKVENKYGSI 558
E+V G L+ + A++Q +F K K+F N +G I
Sbjct: 319 EIVRGTPLFVGDNYFDQFALIQ-----EFFGKPSRKLF----NTWGGI 357
>At2g30980 [G] KOG0658 Glycogen synthase kinase-3
Length = 412
Score = 78.2 bits (191), Expect = 4e-14
Identities = 60/250 (24%), Positives = 115/250 (46%), Gaps = 37/250 (14%)
Query: 289 FQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKENDRSGQ 348
+ A +++G G+FG V + K +VA+K + RY+ EL++++ + +
Sbjct: 72 YMAERVVGTGSFGIVFQAKCLETGESVAIKKVLQDRRYKNR---ELQLMRLMDHPNVVSL 128
Query: 349 YQCLLLREFFDYKNHICLVTDLYGRSVYDFMTN--NGYARFPGSHVQAIGKQLVRSVCFL 406
C D + + LV + ++Y + + + R P +V+ Q+ R + ++
Sbjct: 129 KHCFFSTTTRD-ELFLNLVMEYVPETLYRVLKHYTSSNQRMPIFYVKLYTYQIFRGLAYI 187
Query: 407 HDL-GIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKLID 465
H G+ H D+KP+N+L+ D LT + KL G K+L+ E +
Sbjct: 188 HTAPGVCHRDVKPQNLLV---------------DPLTHQCKLCDFGSAKVLVKGEANI-- 230
Query: 466 FGSAVFYNEYHPPVVSTRHYRAPEIVLGLG-WSFPCDIWSIACVLVELVTGESLYPIHEN 524
+ +R+YRAPE++ G ++ DIWS CVL EL+ G+ L+P +
Sbjct: 231 ------------SYICSRYYRAPELIFGATEYTSSIDIWSAGCVLAELLLGQPLFPGENS 278
Query: 525 TEHMAMMQRI 534
+ + + ++
Sbjct: 279 VDQLVEIIKV 288
>Hs21237745 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 424
Score = 77.8 bits (190), Expect = 5e-14
Identities = 70/266 (26%), Positives = 111/266 (41%), Gaps = 50/266 (18%)
Query: 265 MDRFKTDEEGHYVYQENDIFAK-NRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAV 323
M K D + + V + F R+Q ++ +G G G V D + I VAVK +
Sbjct: 1 MSDSKCDSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRP 60
Query: 324 DRYRQAAKTELRVLQTIKENDRSGQYQCL-------LLREFFDYKNHICLVTDLYGRSVY 376
+ + AK R L +K + L L EF D + LV +L ++
Sbjct: 61 FQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQD----VYLVMELMDANLC 116
Query: 377 DFMTNNGYARFPGSHVQAIGKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPME 436
+ + + + Q++ + LH GIIH DLKP NI++ + +
Sbjct: 117 QVI----HMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTL------- 165
Query: 437 IIDSLTERRKLASGGKRKILINPEVKLIDFGSA--VFYNEYHPPVVSTRHYRAPEIVLGL 494
K++DFG A N P V TR+YRAPE++LG+
Sbjct: 166 -------------------------KILDFGLARTACTNFMMTPYVVTRYYRAPEVILGM 200
Query: 495 GWSFPCDIWSIACVLVELVTGESLYP 520
G+ DIWS+ C++ E+V + L+P
Sbjct: 201 GYKENVDIWSVGCIMAEMVLHKVLFP 226
>Hs21237742 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 382
Score = 77.8 bits (190), Expect = 5e-14
Identities = 70/266 (26%), Positives = 111/266 (41%), Gaps = 50/266 (18%)
Query: 265 MDRFKTDEEGHYVYQENDIFAK-NRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAV 323
M K D + + V + F R+Q ++ +G G G V D + I VAVK +
Sbjct: 1 MSDSKCDSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRP 60
Query: 324 DRYRQAAKTELRVLQTIKENDRSGQYQCL-------LLREFFDYKNHICLVTDLYGRSVY 376
+ + AK R L +K + L L EF D + LV +L ++
Sbjct: 61 FQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQD----VYLVMELMDANLC 116
Query: 377 DFMTNNGYARFPGSHVQAIGKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPME 436
+ + + + Q++ + LH GIIH DLKP NI++ + +
Sbjct: 117 QVI----HMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTL------- 165
Query: 437 IIDSLTERRKLASGGKRKILINPEVKLIDFGSA--VFYNEYHPPVVSTRHYRAPEIVLGL 494
K++DFG A N P V TR+YRAPE++LG+
Sbjct: 166 -------------------------KILDFGLARTACTNFMMTPYVVTRYYRAPEVILGM 200
Query: 495 GWSFPCDIWSIACVLVELVTGESLYP 520
G+ DIWS+ C++ E+V + L+P
Sbjct: 201 GYKENVDIWSVGCIMAEMVLHKVLFP 226
>Hs20986521 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 427
Score = 77.8 bits (190), Expect = 5e-14
Identities = 70/302 (23%), Positives = 128/302 (42%), Gaps = 51/302 (16%)
Query: 265 MDRFKTDEEGHYVYQENDIFAK-NRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAV 323
M R K D + V + F R+Q ++ +G G G V D + + VA+K +
Sbjct: 1 MSRSKRDNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRP 60
Query: 324 DRYRQAAKT---ELRVLQTIKENDRSGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMT 380
+ + AK EL +++ + + G ++ + + +V +L ++ +
Sbjct: 61 FQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ 120
Query: 381 NNGYARFPGSHVQAIGKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDS 440
+ + Q++ + LH GIIH DLKP NI++ + +
Sbjct: 121 ----MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTL----------- 165
Query: 441 LTERRKLASGGKRKILINPEVKLIDFGSA--VFYNEYHPPVVSTRHYRAPEIVLGLGWSF 498
K++DFG A + P V TR+YRAPE++LG+G+
Sbjct: 166 ---------------------KILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGYKE 204
Query: 499 PCDIWSIACVLVELVTGESLYPIHENTEHMAMMQRINNE------KFPKKMVEKMFFKVE 552
DIWS+ C++ E++ G L+P T+H+ ++ + +F KK+ + VE
Sbjct: 205 NVDIWSVGCIMGEMIKGGVLFP---GTDHIDQWNKVIEQLGTPCPEFMKKLQPTVRTYVE 261
Query: 553 NK 554
N+
Sbjct: 262 NR 263
>Hs20986519 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 384
Score = 77.8 bits (190), Expect = 5e-14
Identities = 70/302 (23%), Positives = 128/302 (42%), Gaps = 51/302 (16%)
Query: 265 MDRFKTDEEGHYVYQENDIFAK-NRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAV 323
M R K D + V + F R+Q ++ +G G G V D + + VA+K +
Sbjct: 1 MSRSKRDNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRP 60
Query: 324 DRYRQAAKT---ELRVLQTIKENDRSGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMT 380
+ + AK EL +++ + + G ++ + + +V +L ++ +
Sbjct: 61 FQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ 120
Query: 381 NNGYARFPGSHVQAIGKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDS 440
+ + Q++ + LH GIIH DLKP NI++ + +
Sbjct: 121 ----MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTL----------- 165
Query: 441 LTERRKLASGGKRKILINPEVKLIDFGSA--VFYNEYHPPVVSTRHYRAPEIVLGLGWSF 498
K++DFG A + P V TR+YRAPE++LG+G+
Sbjct: 166 ---------------------KILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGYKE 204
Query: 499 PCDIWSIACVLVELVTGESLYPIHENTEHMAMMQRINNE------KFPKKMVEKMFFKVE 552
DIWS+ C++ E++ G L+P T+H+ ++ + +F KK+ + VE
Sbjct: 205 NVDIWSVGCIMGEMIKGGVLFP---GTDHIDQWNKVIEQLGTPCPEFMKKLQPTVRTYVE 261
Query: 553 NK 554
N+
Sbjct: 262 NR 263
>CE21401 [G] KOG0658 Glycogen synthase kinase-3
Length = 362
Score = 77.8 bits (190), Expect = 5e-14
Identities = 60/240 (25%), Positives = 113/240 (47%), Gaps = 53/240 (22%)
Query: 293 QLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKENDRSGQYQCL 352
+++G G+FG V K + VA+K + R++ EL++++ + + +
Sbjct: 40 KVIGNGSFGVVFLAKLSTTNEMVAIKKVLQDKRFKNR---ELQIMRKLNHPN-------I 89
Query: 353 LLREFFDYKN-------HICLVTDLYGRSVYDFMTNNGYAR--FPGSHVQAIGKQLVRSV 403
+ ++F Y + ++ L+ + +VY + R P +V+ QL+RS+
Sbjct: 90 VKLKYFFYSSGEKKDELYLNLILEYVPETVYRVARHYSKQRQQIPMIYVKLYMYQLLRSL 149
Query: 404 CFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKL 463
++H +GI H D+KP+N+LI E+ V +KL
Sbjct: 150 AYIHSIGICHRDIKPQNLLIDPESGV-------------------------------LKL 178
Query: 464 IDFGSAVFY--NEYHPPVVSTRHYRAPEIVLG-LGWSFPCDIWSIACVLVELVTGESLYP 520
DFGSA + NE + + +R+YRAPE++ G ++ D+WS V+ EL+ G+ ++P
Sbjct: 179 CDFGSAKYLVRNEPNVSYICSRYYRAPELIFGATNYTNSIDVWSAGTVMAELLLGQPIFP 238
>At5g26751 [G] KOG0658 Glycogen synthase kinase-3
Length = 413
Score = 77.8 bits (190), Expect = 5e-14
Identities = 62/252 (24%), Positives = 115/252 (45%), Gaps = 41/252 (16%)
Query: 289 FQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKENDRSGQ 348
+ A +++G G+FG V + K TVA+K + RY+ EL+ ++ + +
Sbjct: 69 YMAERVVGHGSFGVVFQAKCLETGETVAIKKVLQDRRYK---NRELQTMRLLDHPNVVSL 125
Query: 349 YQCLLLREFFDYKNHICLVTDLYGRSVYDFMT--NNGYARFPGSHVQAIGKQLVRSVCFL 406
C D + ++ LV + +V+ + N R P +V+ Q+ R++ ++
Sbjct: 126 KHCFFSTTEKD-ELYLNLVLEYVPETVHRVIKHYNKLNQRMPLIYVKLYTYQIFRALSYI 184
Query: 407 HD-LGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKLID 465
H +G+ H D+KP+N+L+ T +VKL D
Sbjct: 185 HRCIGVCHRDIKPQNLLVNPHT-------------------------------HQVKLCD 213
Query: 466 FGSAVFYNEYHPPV--VSTRHYRAPEIVLG-LGWSFPCDIWSIACVLVELVTGESLYPIH 522
FGSA + P + + +R+YRAPE++ G ++ D+WS CVL EL+ G+ L+P
Sbjct: 214 FGSAKVLVKGEPNISYICSRYYRAPELIFGATEYTTAIDVWSAGCVLAELLLGQPLFPGE 273
Query: 523 ENTEHMAMMQRI 534
+ + + ++
Sbjct: 274 SGVDQLVEIIKV 285
>CE12408 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 527
Score = 77.4 bits (189), Expect = 7e-14
Identities = 64/236 (27%), Positives = 105/236 (44%), Gaps = 40/236 (16%)
Query: 288 RFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKENDRSG 347
R+ + LG GTFG+V+ K VA+K ++ + + E L+ +K +
Sbjct: 44 RYLMTKRLGDGTFGEVMLAKKIDTGDRVAIKRMKK----KFYSWEEAMSLREVKSLKKLN 99
Query: 348 QYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQLVRSVCFLH 407
+ LRE + + V + ++Y+ M + FP S ++ I Q+++ + F+H
Sbjct: 100 HPNIIKLREVIRENDILYFVFEFMQENLYELMKDRD-RYFPESVIRNIIYQVLQGLAFMH 158
Query: 408 DLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKLIDFG 467
G H D+KPENI+ C+ T + VK+ DFG
Sbjct: 159 KNGFFHRDMKPENIM-CNGTEL-------------------------------VKIADFG 186
Query: 468 SAVFYNEYHP--PVVSTRHYRAPEIVL-GLGWSFPCDIWSIACVLVELVTGESLYP 520
A P VSTR YRAPEI+L ++ P D+W++ C++ EL L+P
Sbjct: 187 LAREIRSKPPYTDYVSTRWYRAPEILLRSTSYNSPIDMWALGCIMAELYILRPLFP 242
>YJL106w [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 645
Score = 77.0 bits (188), Expect = 9e-14
Identities = 74/266 (27%), Positives = 121/266 (44%), Gaps = 47/266 (17%)
Query: 287 NRFQAMQLLGQGTFGKVVKCKDY--LNDITVAVKIIRA--VDRYRQ-------------A 329
+R+Q ++ LG G+FG V K L++I IR +D+ + A
Sbjct: 36 DRYQLIEKLGAGSFGCVTLAKAQFPLSNILGKQHDIRGTLMDQPKNGHQNYITKTQGVVA 95
Query: 330 AKTELRVLQTIKENDRSGQYQCLL-----------LREFFDYKNH-ICLVTDLYGRSVYD 377
KT + L T+++ R + + +L F D +N+ + +V + +++Y
Sbjct: 96 IKTMMTKLHTLQDYTRVREIKFILAIPANDHLIQIFEVFIDSENYQLHIVMECMEQNLYQ 155
Query: 378 FMTNNGYARFPGSHVQAIGKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEI 437
M + F +++I Q++ + +H+ H DLKPENILI T Q E
Sbjct: 156 MMKHRRRRVFSIPSLKSILSQILAGLKHIHEHNFFHRDLKPENILITPST---QYFEKEY 212
Query: 438 IDSLTERRKLASGGKRKILINPEVKLIDFGSAVFYNEYHP--PVVSTRHYRAPEIVLGLG 495
++ + + N +KL DFG A +P VSTR YR+PEI+L G
Sbjct: 213 MNQIGYQD------------NYVIKLADFGLARHVENKNPYTAYVSTRWYRSPEILLRSG 260
Query: 496 -WSFPCDIWSIACVLVELVTGESLYP 520
+S P DIW+ CV VE+ +L+P
Sbjct: 261 YYSKPLDIWAFGCVAVEVTVFRALFP 286
>At3g61160 [G] KOG0658 Glycogen synthase kinase-3
Length = 431
Score = 76.6 bits (187), Expect = 1e-13
Identities = 72/309 (23%), Positives = 129/309 (41%), Gaps = 69/309 (22%)
Query: 289 FQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKENDRSGQ 348
++A ++G G+FG V + K + VA+K + RY+ R LQ ++ D
Sbjct: 102 YRAEHVIGTGSFGVVFQAKCLETEEKVAIKKVLQDKRYKN------RELQIMRMLDHPNV 155
Query: 349 YQCLLLREFFDYKN----HICLVTDLYGRSVYDFMTNNGYARF----PGSHVQAIGKQLV 400
+ L FF ++ LV + ++Y + Y + P ++Q Q+
Sbjct: 156 VE--LKHSFFSTTEKDELYLNLVLEYVPETIY--RASRSYTKMNQHMPLIYIQLYTYQIC 211
Query: 401 RSVCFLHDL-GIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINP 459
R++ +LH + G+ H D+KP+N+L+ + T
Sbjct: 212 RAMNYLHQVVGVCHRDIKPQNLLVNNVT-------------------------------H 240
Query: 460 EVKLIDFGSAVFYNEYHPPV--VSTRHYRAPEIVLGLG-WSFPCDIWSIACVLVELVTGE 516
EVK+ DFGSA P + + +R+YRAPE++ G ++ D+WS+ CV+ EL G
Sbjct: 241 EVKICDFGSAKMLIPGEPNISYICSRYYRAPELIFGATEYTSAIDMWSVGCVMAELFLGH 300
Query: 517 SLYPIHENTEHMA----------------MMQRINNEKFPKKMVEKMFFKVENKYGSIPT 560
L+P + + + M R N+ KFP+ + +
Sbjct: 301 PLFPGETSVDQLVEIIKILGTPAREEIKNMNPRYNDFKFPQIKAQPWHKIFRRQVSPEAM 360
Query: 561 DLQTSVVKY 569
DL + +++Y
Sbjct: 361 DLASRLLQY 369
>At5g19010 [T] KOG0660 Mitogen-activated protein kinase
Length = 567
Score = 75.5 bits (184), Expect = 3e-13
Identities = 72/272 (26%), Positives = 121/272 (44%), Gaps = 52/272 (19%)
Query: 287 NRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKT---ELRVLQTIKEN 343
+R++ +++G+G++G V D VA+K I + + A E+++L+ ++
Sbjct: 23 SRYRIEEVIGKGSYGVVCSAYDTHTGEKVAIKKINDIFEHVSDATRILREIKLLRLLRHP 82
Query: 344 DRSGQYQCLL---LREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQLV 400
D LL REF D I +V +L ++ + N H Q QL+
Sbjct: 83 DIVEIKHILLPPSRREFRD----IYVVFELMESDLHQVIKAND--DLTPEHYQFFLYQLL 136
Query: 401 RSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPE 460
R + ++H + H DLKP+NIL + C + K+ G ++ N
Sbjct: 137 RGLKYIHTANVFHRDLKPKNIL-ANADC---------------KLKICDFGLARVAFN-- 178
Query: 461 VKLIDFGSAVFYNEYHPPVVSTRHYRAPEIVLGLGWSFP--CDIWSIACVLVELVTGESL 518
D +A+F+ +Y V+TR YRAPE+ + DIWSI C+ EL+TG+ L
Sbjct: 179 ----DTPTAIFWTDY----VATRWYRAPELCGSFFSKYTPAIDIWSIGCIFAELLTGKPL 230
Query: 519 YP----IHE--------NTEHMAMMQRINNEK 538
+P +H+ T + R+ NEK
Sbjct: 231 FPGKNVVHQLDLMTDMLGTPSAEAIGRVRNEK 262
>At3g45640 [T] KOG0660 Mitogen-activated protein kinase
Length = 370
Score = 75.5 bits (184), Expect = 3e-13
Identities = 62/250 (24%), Positives = 108/250 (42%), Gaps = 49/250 (19%)
Query: 295 LGQGTFGKVVKCKDY-LNDITVAVKIIRAVDRYRQAAKTELRVLQTIKENDRSGQYQCL- 352
+G+G +G V D N++ KI A D + A +T LR ++ ++ D
Sbjct: 44 IGRGAYGIVCSVLDTETNELVAMKKIANAFDNHMDAKRT-LREIKLLRHLDHENIIAIRD 102
Query: 353 -----LLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQLVRSVCFLH 407
L R+F D + + T+L ++ + +N H Q QL+R + ++H
Sbjct: 103 VVPPPLRRQFSD----VYISTELMDTDLHQIIRSN--QSLSEEHCQYFLYQLLRGLKYIH 156
Query: 408 DLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKLIDFG 467
IIH DLKP N+L+ N ++K+ DFG
Sbjct: 157 SANIIHRDLKPSNLLLN--------------------------------ANCDLKICDFG 184
Query: 468 SA--VFYNEYHPPVVSTRHYRAPEIVLGLG-WSFPCDIWSIACVLVELVTGESLYPIHEN 524
A N++ V TR YRAPE++L ++ D+WS+ C+ +EL+ + L+P ++
Sbjct: 185 LARPTSENDFMTEYVVTRWYRAPELLLNSSDYTAAIDVWSVGCIFMELMNRKPLFPGKDH 244
Query: 525 TEHMAMMQRI 534
M ++ +
Sbjct: 245 VHQMRLLTEL 254
>At1g57870 [G] KOG0658 Glycogen synthase kinase-3
Length = 420
Score = 75.5 bits (184), Expect = 3e-13
Identities = 65/267 (24%), Positives = 114/267 (42%), Gaps = 75/267 (28%)
Query: 291 AMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKENDRSGQYQ 350
A ++G G+FG V + K VA+K + RY+ EL+++Q +
Sbjct: 84 AEHVVGTGSFGMVFQAKCRETGEVVAIKKVLQDKRYKNR---ELQIMQML---------- 130
Query: 351 CLLLREFFDYKNHICLVTDLYGRS---------VYDFM------TNNGYARF----PGSH 391
D+ N +CL Y R+ V +F+ T Y+R P +
Sbjct: 131 --------DHPNVVCLKHSFYSRTENEEVYLNLVLEFVPETVNRTARSYSRMNQLMPLIY 182
Query: 392 VQAIGKQLVRSVCFLHDL-GIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASG 450
V+ Q+ R + +LH+ G+ H D+KP+N+L+ T
Sbjct: 183 VKLYTYQICRGLAYLHNCCGLCHRDIKPQNLLVNPHT----------------------- 219
Query: 451 GKRKILINPEVKLIDFGSAVFYNEYHPPV--VSTRHYRAPEIVLG-LGWSFPCDIWSIAC 507
++K+ DFGSA + P + + +R+YRAPE++ G ++ DIWS C
Sbjct: 220 --------HQLKICDFGSAKVLVKGEPNISYICSRYYRAPELIFGATEYTTAIDIWSTGC 271
Query: 508 VLVELVTGESLYPIHENTEHMAMMQRI 534
V+ EL+ G+ L+P + + + ++
Sbjct: 272 VMAELLLGQPLFPGESGVDQLVEIIKV 298
>SPAC1687.15 [G] KOG0658 Glycogen synthase kinase-3
Length = 387
Score = 75.1 bits (183), Expect = 3e-13
Identities = 64/253 (25%), Positives = 109/253 (42%), Gaps = 43/253 (16%)
Query: 289 FQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKENDRSGQ 348
+ + +++G G+FG V++ +D A+K + R++ +R+++ D
Sbjct: 32 YTSSKVVGSGSFGVVMQVHLIESDSKAAIKRVLQDKRFKNRELQIMRIMKHPNIVDLIAY 91
Query: 349 YQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYAR----FPGSHVQAIGKQLVRSVC 404
Y Y N LV + ++Y + Y R P V+ QL+RS+
Sbjct: 92 YYTTGDNSDEVYLN---LVLEFMPETIY--RASRLYTRQKLSMPMLEVKLYIYQLLRSLA 146
Query: 405 FLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKLI 464
++H GI H D+KP+N+L+ E N +KL
Sbjct: 147 YIHASGICHRDIKPQNLLLDPE-------------------------------NGILKLC 175
Query: 465 DFGSAVFYNEYHPPV--VSTRHYRAPEIVLG-LGWSFPCDIWSIACVLVELVTGESLYPI 521
DFGSA P V + +R+YRAPE++ G ++ DIWS CV+ EL+ G L+P
Sbjct: 176 DFGSAKILVAGEPNVSYICSRYYRAPELIFGATDYTHAIDIWSTGCVMAELMLGHPLFPG 235
Query: 522 HENTEHMAMMQRI 534
+ + + +I
Sbjct: 236 ESGIDQLVEIIKI 248
>CE17062 [T] KOG0660 Mitogen-activated protein kinase
Length = 448
Score = 75.1 bits (183), Expect = 3e-13
Identities = 77/313 (24%), Positives = 132/313 (41%), Gaps = 55/313 (17%)
Query: 289 FQAMQLLGQGTFGKVVKCKDYLNDITVAVK-IIRAVDRYRQAAKT--ELRVLQTIKENDR 345
+ +++ LG+G +G V + VA+K R A +T EL++L+T++ ++
Sbjct: 49 YNSLKPLGEGAYGVVCTAEYEPTGDRVAIKKFFRPFQSTIHAKRTYRELKLLRTLQHDNV 108
Query: 346 SGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQLVRSV-- 403
N++ V+ L G + + M R +Q + Q++R +
Sbjct: 109 LEMIDVFTPDPDASSLNNVYFVSVLMGSDLQNIMK---IQRLTDEQIQLLIYQVLRGLKY 165
Query: 404 ---------------------------CFLHDLGIIHTDLKPENILICDETCVEQSLPME 436
++H GIIH DLKP NI + +E C
Sbjct: 166 MSHQNFNSTIILKKLMHPFQRRNTRFRLYIHSAGIIHRDLKPSNIAV-NERC-------- 216
Query: 437 IIDSLTERRKLASGGKRKILINPEVKLIDFGSAVFYNEYHPPVVSTRHYRAPEIVLG-LG 495
E + S + LI K++DFG A + V+TR YRAPEI+L +
Sbjct: 217 ------EVKVFLSFSQLSFLILSFFKILDFGLARAQDAEMTGYVATRWYRAPEIMLNWMH 270
Query: 496 WSFPCDIWSIACVLVELVTGESLYP----IHENTEHMAMMQRINNEKFPKKMVEKMFFKV 551
++ D+WS+ C+L ELV+G L+P I + T+ M+++ E + K E+ +
Sbjct: 271 YTQTVDVWSVGCILAELVSGRPLFPGDDHIDQLTKIMSVVGTPKEEFWSKIQSEEARNYI 330
Query: 552 ENKYGSIPTDLQT 564
+N+ I D T
Sbjct: 331 KNRSPIIRQDFVT 343
>At3g17850 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1263
Score = 75.1 bits (183), Expect = 3e-13
Identities = 66/260 (25%), Positives = 118/260 (45%), Gaps = 20/260 (7%)
Query: 289 FQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKENDRSGQ 348
F+ ++ + +G FG+V K A+K+++ D R+ A + + I N R+
Sbjct: 890 FEIIKPISRGAFGRVFLAKKRTTGDLFAIKVLKKADMIRKNAVESILAERDILINVRNP- 948
Query: 349 YQCLLLREFFDY--KNHICLVTD-LYGRSVYDFMTNNGYARFPGSHVQAIGKQLVRSVCF 405
++R F+ + ++++ LV + L G +Y + N G V+ ++V ++ +
Sbjct: 949 ---FVVRFFYSFTCRDNLYLVMEYLNGGDLYSLLRNLGCLE--EDIVRVYIAEVVLALEY 1003
Query: 406 LHDLGIIHTDLKPENILICDETCVEQS----LPMEIIDSLTERRKLASGGKRKILINPEV 461
LH G++H DLKP+N+LI + ++ + + +I+S + A G L++ E
Sbjct: 1004 LHSEGVVHRDLKPDNLLIAHDGHIKLTDFGLSKVGLINSTDDLAGPAVSGTS--LLDEEE 1061
Query: 462 KLIDFGSAVFYNEYHPPVVSTRHYRAPEIVLGLGWSFPCDIWSIACVLVELVTGESLYPI 521
+ V T Y APEI+LG G D WS+ +L EL+ G +
Sbjct: 1062 SRLAASEEQLERRKKRSAVGTPDYLAPEILLGTGHGATADWWSVGIILFELIVGIPPF-- 1119
Query: 522 HENTEH-MAMMQRINNEKFP 540
N EH + I N K P
Sbjct: 1120 --NAEHPQQIFDNILNRKIP 1137
>At1g18150 [T] KOG0660 Mitogen-activated protein kinase
Length = 589
Score = 75.1 bits (183), Expect = 3e-13
Identities = 72/272 (26%), Positives = 121/272 (44%), Gaps = 52/272 (19%)
Query: 287 NRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKT---ELRVLQTIKEN 343
NR+Q +++G+G++G V D VA+K I V + A E+++L+ ++
Sbjct: 102 NRYQIQEVVGKGSYGVVASAVDSHTGERVAIKKINDVFEHVSDATRILREIKLLRLLRHP 161
Query: 344 DRSGQYQCLL---LREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQLV 400
D +L REF D I +V +L ++ + N H Q QL+
Sbjct: 162 DVVEIKHIMLPPSRREFRD----IYVVFELMESDLHQVIKAND--DLTPEHYQFFLYQLL 215
Query: 401 RSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPE 460
R + ++H + H DLKP+NIL + C + K+ G ++ N
Sbjct: 216 RGLKYVHAANVFHRDLKPKNIL-ANADC---------------KLKICDFGLARVSFN-- 257
Query: 461 VKLIDFGSAVFYNEYHPPVVSTRHYRAPEIVLGL--GWSFPCDIWSIACVLVELVTGESL 518
D +A+F+ +Y V+TR YRAPE+ ++ DIWS+ C+ E++ G+ L
Sbjct: 258 ----DAPTAIFWTDY----VATRWYRAPELCGSFFSKYTPAIDIWSVGCIFAEMLLGKPL 309
Query: 519 YP----IHE--------NTEHMAMMQRINNEK 538
+P +H+ T + RI NEK
Sbjct: 310 FPGKNVVHQLDLMTDFLGTPPPESISRIRNEK 341
>At1g18040 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 391
Score = 75.1 bits (183), Expect = 3e-13
Identities = 58/231 (25%), Positives = 103/231 (44%), Gaps = 40/231 (17%)
Query: 287 NRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKENDRS 346
+R+ ++LGQGT+G V K D + TVA+K IR + T LR ++ +KE
Sbjct: 10 DRYLKQEVLGQGTYGVVFKATDTKTEQTVAIKKIRLGKQREGVNITALREIKMLKELKHP 69
Query: 347 GQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQLVRSVCFL 406
+LL + F +K ++ LV + + + ++ P + +++ + + +
Sbjct: 70 ---HIILLIDAFPHKENLHLVFEFMETDLEAVIRDSNIFLSP-ADIKSYLLMTFKGLAYC 125
Query: 407 HDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKLIDF 466
HD ++H D+KP N+LI ++ ++KL DF
Sbjct: 126 HDKWVLHRDMKPNNLLIG--------------------------------VDGQLKLADF 153
Query: 467 GSAVFY---NEYHPPVVSTRHYRAPEIVLGL-GWSFPCDIWSIACVLVELV 513
G A + N V R YRAPE++ G + D+W++AC+ EL+
Sbjct: 154 GLARIFGSPNRKFTHQVFARWYRAPELLFGAKQYGAAVDVWAVACIFAELL 204
>7293139 [T] KOG1290 Serine/threonine protein kinase
Length = 790
Score = 75.1 bits (183), Expect = 3e-13
Identities = 51/174 (29%), Positives = 89/174 (50%), Gaps = 9/174 (5%)
Query: 256 GSHQDKLRSMDRFKTDEEGHYVYQENDIFAKNRFQAMQLLGQGTFGKVVKCKDYLNDITV 315
GS D+ S + + G++ D+F NR+ + LG G F V C D D
Sbjct: 173 GSGFDRQESANEYVIG--GYHPVAIGDVFV-NRYHVFKKLGWGHFSTVWLCYDTQMDRYC 229
Query: 316 AVKIIRAVDRYRQAAKTELRVLQTIKENDRSGQYQCLL-LREFFD----YKNHICLVTDL 370
AVK+ ++ Y++ E+ + + +D+ ++ +FF+ + HICLV ++
Sbjct: 230 AVKVSKSAQVYKETGIDEIMLFSQMSLHDQHKYRSHVVGFYDFFEITGPHGRHICLVLEV 289
Query: 371 YGRSVYDFMTNNGYARFPGSHVQAIGKQLVRSVCFLH-DLGIIHTDLKPENILI 423
G ++ + Y P S+++ I +Q++ + FLH + GIIHTDLKPEN+L+
Sbjct: 290 LGDNLLKVIERCFYKGMPISNIKQIAQQVLTGLKFLHEECGIIHTDLKPENVLL 343
Score = 61.6 bits (148), Expect = 4e-09
Identities = 26/62 (41%), Positives = 40/62 (63%)
Query: 461 VKLIDFGSAVFYNEYHPPVVSTRHYRAPEIVLGLGWSFPCDIWSIACVLVELVTGESLYP 520
VK+ D G+A +++ + + T+ YRA E++LG G+ DIWS+AC+L EL TG L+
Sbjct: 561 VKIADLGNACYFHHHFTDDIQTKEYRALEVILGAGYCETADIWSVACLLWELATGTYLFD 620
Query: 521 IH 522
H
Sbjct: 621 TH 622
>At1g76540 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 313
Score = 74.7 bits (182), Expect = 4e-13
Identities = 61/243 (25%), Positives = 110/243 (45%), Gaps = 34/243 (13%)
Query: 283 IFAKNRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKE 342
+ A + F+ ++ +G+GT+GKV + ++ VA+K R + T LR + ++
Sbjct: 8 VSAMDAFEKLEKVGEGTYGKVYRAREKATGKIVALKKTRLHEDEEGVPSTTLREISILRM 67
Query: 343 NDRSGQYQCLL-LREFF--DYKNHICLVTDLYGRSVYDFMTN--NGYARFPGSHVQAIGK 397
R L+ +++ + K + LV + V F+ + + P ++++
Sbjct: 68 LARDPHVVRLMDVKQGLSKEGKTVLYLVFEYMDTDVKKFIRSFRSTGKNIPTQTIKSLMY 127
Query: 398 QLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILI 457
QL + + F H GI+H DLKP N+L +D T R K+A G +
Sbjct: 128 QLCKGMAFCHGHGILHRDLKPHNLL---------------MDPKTMRLKIADLGLARAFT 172
Query: 458 NPEVKLIDFGSAVFYNEYHPPVVSTRHYRAPEIVLG-LGWSFPCDIWSIACVLVELVTGE 516
P K + + T YRAPE++LG +S D+WS+ C+ ELVT +
Sbjct: 173 LPMKK-------------YTHEILTLWYRAPEVLLGATHYSTAVDMWSVGCIFAELVTNQ 219
Query: 517 SLY 519
+++
Sbjct: 220 AIF 222
>Hs4506081 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 422
Score = 74.3 bits (181), Expect = 6e-13
Identities = 70/274 (25%), Positives = 115/274 (41%), Gaps = 50/274 (18%)
Query: 257 SHQDKLRSMDRFKTDEEGHYVYQENDIFAK-NRFQAMQLLGQGTFGKVVKCKDYLNDITV 315
S+ K +M + K D + + V + F R+Q ++ +G G G V D + D V
Sbjct: 31 SYIAKHYNMSKSKVDNQFYSVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNV 90
Query: 316 AVKIIRAVDRYRQAAKTELRVLQTIKENDRSGQYQCL-------LLREFFDYKNHICLVT 368
A+K + + + AK R L +K + L L EF D + LV
Sbjct: 91 AIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIISLLNVFTPQKTLEEFQD----VYLVM 146
Query: 369 DLYGRSVYDFMTNNGYARFPGSHVQAIGKQLVRSVCFLHDLGIIHTDLKPENILICDETC 428
+L ++ + + + Q++ + LH GIIH DLKP NI++ +
Sbjct: 147 ELMDANLCQVIQ----MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCT 202
Query: 429 VEQSLPMEIIDSLTERRKLASGGKRKILINPEVKLIDFGSA--VFYNEYHPPVVSTRHYR 486
+ K++DFG A + P V TR+YR
Sbjct: 203 L--------------------------------KILDFGLARTAGTSFMMTPYVVTRYYR 230
Query: 487 APEIVLGLGWSFPCDIWSIACVLVELVTGESLYP 520
APE++LG+G+ DIWS+ C++ E+V + L+P
Sbjct: 231 APEVILGMGYKENVDIWSVGCIMGEMVRHKILFP 264
>Hs4502735 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 303
Score = 74.3 bits (181), Expect = 6e-13
Identities = 65/248 (26%), Positives = 107/248 (42%), Gaps = 48/248 (19%)
Query: 285 AKNRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRA-----------VDRYRQAAKTE 333
A +R++ + +G G +G V K +D + VA+K +R + R+ A
Sbjct: 2 ATSRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGGGGGLPISTVREVAL-- 59
Query: 334 LRVLQTIKENDRSGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQ 393
LR L+ E+ + + D + + LV + + + ++ P ++
Sbjct: 60 LRRLEAF-EHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIK 118
Query: 394 AIGKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKR 453
+ +Q +R + FLH I+H DLKPENIL+ SGG
Sbjct: 119 DLMRQFLRGLDFLHANCIVHRDLKPENILV------------------------TSGGT- 153
Query: 454 KILINPEVKLIDFGSAVFYNEYHP--PVVSTRHYRAPEIVLGLGWSFPCDIWSIACVLVE 511
VKL DFG A Y+ PVV T YRAPE++L ++ P D+WS+ C+ E
Sbjct: 154 -------VKLADFGLARIYSYQMALTPVVVTLWYRAPEVLLQSTYATPVDMWSVGCIFAE 206
Query: 512 LVTGESLY 519
+ + L+
Sbjct: 207 MFRRKPLF 214
>Hs20986510 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 464
Score = 74.3 bits (181), Expect = 6e-13
Identities = 70/274 (25%), Positives = 115/274 (41%), Gaps = 50/274 (18%)
Query: 257 SHQDKLRSMDRFKTDEEGHYVYQENDIFAK-NRFQAMQLLGQGTFGKVVKCKDYLNDITV 315
S+ K +M + K D + + V + F R+Q ++ +G G G V D + D V
Sbjct: 31 SYIAKHYNMSKSKVDNQFYSVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNV 90
Query: 316 AVKIIRAVDRYRQAAKTELRVLQTIKENDRSGQYQCL-------LLREFFDYKNHICLVT 368
A+K + + + AK R L +K + L L EF D + LV
Sbjct: 91 AIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIISLLNVFTPQKTLEEFQD----VYLVM 146
Query: 369 DLYGRSVYDFMTNNGYARFPGSHVQAIGKQLVRSVCFLHDLGIIHTDLKPENILICDETC 428
+L ++ + + + Q++ + LH GIIH DLKP NI++ +
Sbjct: 147 ELMDANLCQVIQ----MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCT 202
Query: 429 VEQSLPMEIIDSLTERRKLASGGKRKILINPEVKLIDFGSA--VFYNEYHPPVVSTRHYR 486
+ K++DFG A + P V TR+YR
Sbjct: 203 L--------------------------------KILDFGLARTAGTSFMMTPYVVTRYYR 230
Query: 487 APEIVLGLGWSFPCDIWSIACVLVELVTGESLYP 520
APE++LG+G+ DIWS+ C++ E+V + L+P
Sbjct: 231 APEVILGMGYKENVDIWSVGCIMGEMVRHKILFP 264
>Hs17461944 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 385
Score = 74.3 bits (181), Expect = 6e-13
Identities = 76/297 (25%), Positives = 132/297 (43%), Gaps = 52/297 (17%)
Query: 288 RFQAMQLLGQGTFGKVVKCKDYLNDITVAVK-IIRAVDR--YRQAAKTELRVLQTIKEND 344
+++ + G+G++G V KC++ + VAVK + + D ++ A E+R+L+ +K +
Sbjct: 3 KYEKLAKTGEGSYGVVFKCRNKTSGQVVAVKKFVESEDDPVVKKIALREIRMLKQLKHPN 62
Query: 345 RSGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQLVRSVC 404
+ L E F K + LV + ++ + + N S V + RS
Sbjct: 63 ------LVNLIEVFRRKRKMHLVFEYCDHTLLNELERNPNGMDSDSIVGRLRSVADRSRL 116
Query: 405 FLHD-----LGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINP 459
+ L IH D+KPENILI + + K+ G +ILI
Sbjct: 117 APKNNQIMILQCIHRDIKPENILITKQGII----------------KICDFGFAQILIPG 160
Query: 460 EVKLIDFGSAVFYNEYHPPVVSTRHYRAPEIVLG-LGWSFPCDIWSIACVLVELVTGESL 518
+ Y +Y V+TR YRAPE+++G + DIW+I CV EL+TG+ L
Sbjct: 161 DA----------YTDY----VATRWYRAPELLVGDTQYGSSVDIWAIGCVFAELLTGQPL 206
Query: 519 YPIHENTEHMAMMQRINNEKFPKKMVEKMFFKVENKYGSI----PTDLQTSVVKYFD 571
+P + + + ++ R + P+ + FK + I P D++T K+ D
Sbjct: 207 WPGKSDVDQLYLIIRTLGKLIPR---HQSIFKSNGFFHGISIPEPEDMETLEEKFSD 260
>CE29298 [T] KOG0690 Serine/threonine protein kinase
Length = 483
Score = 74.3 bits (181), Expect = 6e-13
Identities = 67/267 (25%), Positives = 114/267 (42%), Gaps = 57/267 (21%)
Query: 289 FQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIR---AVDRYRQA-AKTELRVLQTIKEND 344
F +++LGQGTFGKV+ C++ +D A+KIIR VDR A TE RVL
Sbjct: 180 FDFLKVLGQGTFGKVILCREKSSDKLYAIKIIRKEMVVDRSEVAHTLTENRVL------- 232
Query: 345 RSGQYQCL-----LLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQL 399
Y C+ LL+ F + HIC V + + F F + + G ++
Sbjct: 233 ----YACVHPFLTLLKYSFQAQYHICFVME-FANGGELFTHLQRCKTFSEARTRFYGSEI 287
Query: 400 VRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINP 459
+ ++ +LH I++ D+K EN+L+ +R +
Sbjct: 288 ILALGYLHHRNIVYRDMKLENLLL-------------------DR-------------DG 315
Query: 460 EVKLIDFG---SAVFYNEYHPPVVSTRHYRAPEIVLGLGWSFPCDIWSIACVLVELVTGE 516
+K+ DFG + Y + T Y APE++ + + D W + V+ E++ G
Sbjct: 316 HIKITDFGLCKEEIKYGDKTSTFCGTPEYLAPEVIEDIDYDRSVDWWGVGVVMYEMMCGR 375
Query: 517 SLYPIHENTEHMAMMQRINNEKFPKKM 543
+ EN + ++ + KFP ++
Sbjct: 376 LPFSAKENGKLFELITTC-DLKFPNRL 401
>CE18646 [T] KOG0690 Serine/threonine protein kinase
Length = 528
Score = 74.3 bits (181), Expect = 6e-13
Identities = 67/267 (25%), Positives = 114/267 (42%), Gaps = 57/267 (21%)
Query: 289 FQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIR---AVDRYRQA-AKTELRVLQTIKEND 344
F +++LGQGTFGKV+ C++ +D A+KIIR VDR A TE RVL
Sbjct: 180 FDFLKVLGQGTFGKVILCREKSSDKLYAIKIIRKEMVVDRSEVAHTLTENRVL------- 232
Query: 345 RSGQYQCL-----LLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQL 399
Y C+ LL+ F + HIC V + + F F + + G ++
Sbjct: 233 ----YACVHPFLTLLKYSFQAQYHICFVME-FANGGELFTHLQRCKTFSEARTRFYGSEI 287
Query: 400 VRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINP 459
+ ++ +LH I++ D+K EN+L+ +R +
Sbjct: 288 ILALGYLHHRNIVYRDMKLENLLL-------------------DR-------------DG 315
Query: 460 EVKLIDFG---SAVFYNEYHPPVVSTRHYRAPEIVLGLGWSFPCDIWSIACVLVELVTGE 516
+K+ DFG + Y + T Y APE++ + + D W + V+ E++ G
Sbjct: 316 HIKITDFGLCKEEIKYGDKTSTFCGTPEYLAPEVIEDIDYDRSVDWWGVGVVMYEMMCGR 375
Query: 517 SLYPIHENTEHMAMMQRINNEKFPKKM 543
+ EN + ++ + KFP ++
Sbjct: 376 LPFSAKENGKLFELITTC-DLKFPNRL 401
>7298004 [G] KOG0658 Glycogen synthase kinase-3
Length = 392
Score = 74.3 bits (181), Expect = 6e-13
Identities = 66/246 (26%), Positives = 111/246 (44%), Gaps = 45/246 (18%)
Query: 288 RFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKEND--- 344
R + L+G G+FG+V + ++ VAVK + Q E ++ +K+++
Sbjct: 43 RIEVKDLIGSGSFGRVYQAHVNESEEIVAVKQTLYNPKLSQG---EAEIMGQLKDHNNIV 99
Query: 345 RSGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGS---HVQAIGKQLVR 401
R + + L F +++ LV + ++ D++ + P +V+ + Q+ R
Sbjct: 100 RLIMHSSVSLG--FPSVDYVLLVMEYMPMTLLDYINYHLTVLQPAERLINVRILSYQMFR 157
Query: 402 SVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEV 461
+ +LH LGI H D+KPEN+LI ++ V +
Sbjct: 158 GLGYLHLLGISHRDVKPENLLIDNQKMV-------------------------------L 186
Query: 462 KLIDFGSAVFYNEYHPPV--VSTRHYRAPEIVLGLG-WSFPCDIWSIACVLVELVTGESL 518
KL DFGSA P + + +R YRAPE+ G +S DIWS CVL EL+ G L
Sbjct: 187 KLSDFGSAKLLVPQEPSISYICSRLYRAPELFAGYELYSCAVDIWSAGCVLAELLKGYPL 246
Query: 519 YPIHEN 524
+ H++
Sbjct: 247 FSSHKH 252
>Hs14777335 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 795
Score = 73.9 bits (180), Expect = 8e-13
Identities = 68/254 (26%), Positives = 110/254 (42%), Gaps = 41/254 (16%)
Query: 279 QENDIFAKNRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVD-RYRQAAKTELRVL 337
+E I A ++LG G FG+V +C + + +A KII+ + R+ K E+ ++
Sbjct: 481 KETSISAGYEVCQHEVLGGGRFGQVHRCTEKSTGLPLAAKIIKVKSAKDREDVKNEINIM 540
Query: 338 QTIKENDRSGQYQCLLLREFFDYKNHICLVTDLY-GRSVYDFMTNNGYARFPGSHVQAIG 396
+ + L + F+ K+ LV + G ++D +T+ Y V
Sbjct: 541 NQLSH------VNLIQLYDAFESKHSCTLVMEYVDGGELFDRITDEKY-HLTELDVVLFT 593
Query: 397 KQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKIL 456
+Q+ V +LH I+H DLKPENIL CV Q+
Sbjct: 594 RQICEGVHYLHQHYILHLDLKPENIL-----CVNQT------------------------ 624
Query: 457 INPEVKLIDFGSAVFYNEYHPPVVS--TRHYRAPEIVLGLGWSFPCDIWSIACVLVELVT 514
++K+IDFG A Y V+ T + APE+V SFP D+WS+ + L++
Sbjct: 625 -GHQIKIIDFGLARRYKPREKLKVNFGTPEFLAPEVVNYEFVSFPTDMWSVGVITYMLLS 683
Query: 515 GESLYPIHENTEHM 528
G S + + E M
Sbjct: 684 GLSPFLGETDAETM 697
>ECU08g0230 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 265
Score = 73.9 bits (180), Expect = 8e-13
Identities = 60/248 (24%), Positives = 111/248 (44%), Gaps = 53/248 (21%)
Query: 294 LLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKENDRSGQYQCLL 353
L+G GT+G+V + D VA+K IR ++ T LR + +K+
Sbjct: 9 LIGSGTYGEVYEAIDTETKEKVALKRIRLNEKEGMPG-TALREISILKK----------- 56
Query: 354 LREFFDYKNHICLVTDLYGRSVY-------DFMTNNGYARFPGSHVQAIGKQLVRSVCFL 406
++N I LV+ ++ ++ D+ G ++ + QL+ V +L
Sbjct: 57 ----LSHRNIISLVSIIHTDALLTMVFPFIDYELKKYIGMNTGKNIMELVNQLICGVHYL 112
Query: 407 HDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKLIDF 466
H + ++H DLKP+NIL+ + + K+A G + L E+++ +
Sbjct: 113 HRMNVVHRDLKPQNILVTSDGVL----------------KIADFGLSRSL---EIRVPPY 153
Query: 467 GSAVFYNEYHPPVVSTRHYRAPEIVLG-LGWSFPCDIWSIACVLVELVTGESLYPIHENT 525
S V T YR+PE+++G + F DIWS+ C++ E++T E L+P
Sbjct: 154 SSEVV----------TLWYRSPELLMGSTSYRFYVDIWSLGCIIYEMITLEPLFPGESKE 203
Query: 526 EHMAMMQR 533
+ +++R
Sbjct: 204 NQLTLIRR 211
>CE18967 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD and related
proteins
Length = 1101
Score = 73.9 bits (180), Expect = 8e-13
Identities = 70/289 (24%), Positives = 123/289 (42%), Gaps = 45/289 (15%)
Query: 256 GSHQDKLRSMDRFKTDEEGHYVYQENDIFAKNRFQAMQLLGQGTFGKVVKCKDYLNDITV 315
G DKL+ +T G + E++ + A ++LG G FG V N V
Sbjct: 737 GKRIDKLKVPTEGETGHLGAKIQTEHEFSQLYQIFAEEVLGSGQFGTVYGGIHRRNGQHV 796
Query: 316 AVKIIRAVD---RYRQAAKTELRVLQTIKENDRSGQYQCLLLREFFDYKNHICLVTDLYG 372
AVK+I + + E+++L+ + D G + + E D I +V +
Sbjct: 797 AVKLIDKLKFPPNKEDLLRAEVQILEKV---DHPGVVHFMQMLETTD---RIFVVMEKLK 850
Query: 373 RSVYDFMTNNGYARFPGSHVQAIGKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQS 432
+ + + ++ R Q + Q++ ++ +LH L I+H DLKPENIL+ +
Sbjct: 851 GDMLEMILSSEKGRLSERTTQFLVAQILEALRYLHHLNIVHCDLKPENILLNSNSDF--- 907
Query: 433 LPMEIIDSLTERRKLASGGKRKILINPEVKLIDFGSAVFYNE--YHPPVVSTRHYRAPEI 490
P+VKL DFG A E + VV T Y APE+
Sbjct: 908 --------------------------PQVKLCDFGFARIIGEKSFRRSVVGTPAYLAPEV 941
Query: 491 VLGLGWSFPCDIWSIACVLVELVTGESLYPIHENTEHMAMMQRINNEKF 539
+ G++ D+WS+ ++ ++G +P +E+ + + +I N +F
Sbjct: 942 LRNKGFNRSLDMWSVGVIVYVSLSG--TFPFNEDED---INDQIQNAEF 985
>Hs6912584 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 451
Score = 73.6 bits (179), Expect = 1e-12
Identities = 67/260 (25%), Positives = 115/260 (43%), Gaps = 51/260 (19%)
Query: 289 FQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQ--AAKTELRVLQTIKENDRS 346
++ ++ LG+G++ V K K +N VA+K+IR + A E +L+ +K +
Sbjct: 117 YEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPFTAIREASLLKGLKHAN-- 174
Query: 347 GQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQLVRSVCFL 406
+LL + K + LV + + +M + P +V+ QL+R + ++
Sbjct: 175 ----IVLLHDIIHTKETLTLVFEYVHTDLCQYMDKHPGGLHP-DNVKLFLFQLLRGLSYI 229
Query: 407 HDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKLIDF 466
H I+H DLKP+N+LI D E+KL DF
Sbjct: 230 HQRYILHRDLKPQNLLISD--------------------------------TGELKLADF 257
Query: 467 GSA----VFYNEYHPPVVSTRHYRAPEIVLG-LGWSFPCDIWSIACVLVELVTGESLYP- 520
G A V + Y VV T YR P+++LG +S D+W + C+ VE++ G + +P
Sbjct: 258 GLARAKSVPSHTYSNEVV-TLWYRPPDVLLGSTEYSTCLDMWGVGCIFVEMIQGVAAFPG 316
Query: 521 ---IHENTEHMAMMQRINNE 537
I + E + ++ NE
Sbjct: 317 MKDIQDQLERIFLVLGTPNE 336
>Hs20986506 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 426
Score = 73.6 bits (179), Expect = 1e-12
Identities = 68/266 (25%), Positives = 111/266 (41%), Gaps = 50/266 (18%)
Query: 265 MDRFKTDEEGHYVYQENDIFAK-NRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAV 323
M + K D + + V + F R+Q ++ +G G G V D + D VA+K +
Sbjct: 1 MSKSKVDNQFYSVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRP 60
Query: 324 DRYRQAAKTELRVLQTIKENDRSGQYQCL-------LLREFFDYKNHICLVTDLYGRSVY 376
+ + AK R L +K + L L EF D + LV +L ++
Sbjct: 61 FQNQTHAKRAYRELVLMKCVNHKNIISLLNVFTPQKTLEEFQD----VYLVMELMDANLC 116
Query: 377 DFMTNNGYARFPGSHVQAIGKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPME 436
+ + + Q++ + LH GIIH DLKP NI++ + +
Sbjct: 117 QVIQ----MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTL------- 165
Query: 437 IIDSLTERRKLASGGKRKILINPEVKLIDFGSA--VFYNEYHPPVVSTRHYRAPEIVLGL 494
K++DFG A + P V TR+YRAPE++LG+
Sbjct: 166 -------------------------KILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGM 200
Query: 495 GWSFPCDIWSIACVLVELVTGESLYP 520
G+ DIWS+ C++ E+V + L+P
Sbjct: 201 GYKENVDIWSVGCIMGEMVRHKILFP 226
>CE29466 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 390
Score = 73.6 bits (179), Expect = 1e-12
Identities = 65/241 (26%), Positives = 108/241 (43%), Gaps = 44/241 (18%)
Query: 288 RFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELR---VLQTIKEND 344
R+ + L G G VV D + VA+K ++ +AK R +L TIK +
Sbjct: 37 RYVNLSFLNAGAQGTVVMADDLVTTQRVAIKKMQQPFVMTMSAKRAYREFILLTTIKHPN 96
Query: 345 RSGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYA-----RFPGSHVQAIGKQL 399
+ L F + ++Y V + MT+N + R + Q
Sbjct: 97 ------IIRLLNAFTPDTSLSTFREVY--LVMELMTHNLHEVIHRLRLDHKTLSFFVYQS 148
Query: 400 VRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINP 459
+ ++ LH+ G+IH DLKP NI++ D CV ++++D G RK ++
Sbjct: 149 LCAIKHLHNSGVIHRDLKPSNIVVNDR-CV-----LKVLDF---------GLARKKNVDT 193
Query: 460 EVKLIDFGSAVFYNEYHPPVVSTRHYRAPEIVLGLGWSFPCDIWSIACVLVELVTGESLY 519
+++ D+ V TR+YRAPE++LGL +S DIWS+ C+ E++ L+
Sbjct: 194 SMRMSDY-------------VVTRYYRAPEVILGLPYSEKVDIWSVGCIFAEMINHTVLF 240
Query: 520 P 520
P
Sbjct: 241 P 241
>7297631 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 372
Score = 73.6 bits (179), Expect = 1e-12
Identities = 61/272 (22%), Positives = 114/272 (41%), Gaps = 46/272 (16%)
Query: 270 TDEEGHYVYQEND--IFAKNRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDR-- 325
T + HY + D +R+ ++ +G G G V D + VA+K + +
Sbjct: 3 TAQHQHYTVEVGDTNFTIHSRYINLRPIGSGAQGIVCAAYDTITQQNVAIKKLSRPFQNV 62
Query: 326 -YRQAAKTELRVLQTIKENDRSGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGY 384
+ + A E ++++ + + G + + + LV +L ++ + +
Sbjct: 63 THAKRAYREFKLMKLVNHKNIIGLLNAFTPQRNLEEFQDVYLVMELMDANLCQVIQMD-- 120
Query: 385 ARFPGSHVQAIGKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTER 444
+ + Q++ + LH GIIH DLKP NI++ + +
Sbjct: 121 --LDHDRMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKADCTL--------------- 163
Query: 445 RKLASGGKRKILINPEVKLIDFGSAVFYNEYH--PPVVSTRHYRAPEIVLGLGWSFPCDI 502
K++DFG A P V TR+YRAPE++LG+G++ DI
Sbjct: 164 -----------------KILDFGLARTAGTTFMMTPYVVTRYYRAPEVILGMGYTENVDI 206
Query: 503 WSIACVLVELVTGESLYPIHENTEHMAMMQRI 534
WS+ C++ E++ G L+P T+H+ +I
Sbjct: 207 WSVGCIMGEMIRGGVLFP---GTDHIDQWNKI 235
>7296346 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 952
Score = 73.6 bits (179), Expect = 1e-12
Identities = 69/245 (28%), Positives = 110/245 (44%), Gaps = 53/245 (21%)
Query: 289 FQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKENDRSGQ 348
FQ + + +GT+G V + KD + VA+K ++ T LR + T+ + GQ
Sbjct: 558 FQCLNRIEEGTYGVVYRAKDKRTNEIVALKRLKMEKEKEGFPITSLREINTLLK----GQ 613
Query: 349 YQCLL-LREFFDYKN--HICLVTDLYG---RSVYDFMTNNGYARFPGSHVQAIGKQLVRS 402
+ ++ +RE N I +V D +S+ + M N + FPG V+ + +QL+R+
Sbjct: 614 HPNIVTVREIVVGSNMDKIFIVMDYVEHDLKSLMETMKNRKQSFFPGE-VKCLTQQLLRA 672
Query: 403 VCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVK 462
V LHD I+H DLK N+L+ + +K
Sbjct: 673 VAHLHDNWILHRDLKTSNLLLSHKGI--------------------------------LK 700
Query: 463 LIDFGSAVFYNEYHPPV------VSTRHYRAPEIVL-GLGWSFPCDIWSIACVLVELVTG 515
+ DFG A EY P+ V T YRAPE++L +S P D+WS+ C+ E +
Sbjct: 701 VGDFGLA---REYGSPIKKYTSLVVTLWYRAPELLLCSPVYSTPIDVWSVGCIFAEFLQM 757
Query: 516 ESLYP 520
L+P
Sbjct: 758 LPLFP 762
>YOL045w [T] KOG1152 Signal transduction serine/threonine kinase with PAS/PAC
sensor domain
Length = 1101
Score = 73.2 bits (178), Expect = 1e-12
Identities = 66/244 (27%), Positives = 109/244 (44%), Gaps = 48/244 (19%)
Query: 289 FQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAV---------DRYRQAAKTELRVLQT 339
F +Q++G+G +GKV C V +K+I DR +E++++ T
Sbjct: 841 FTILQVMGEGAYGKVNLCIHNREHYIVVIKMIFKERILVDTWVRDRKLGTIPSEIQIMAT 900
Query: 340 IKENDRSGQYQCLLLREFFDYKNHICLVTDLYGRS-VYDFMTNNGYARFPGSH-VQAIGK 397
+ +N Q L L +FF+ ++ + T ++G + D + + H + + K
Sbjct: 901 LNKNS---QENILKLLDFFEDDDYYYIETPVHGETGSIDLFDVIEFKKDMVEHEAKLVFK 957
Query: 398 QLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILI 457
Q+V S+ LHD GI+H D+K EN+ I+DS
Sbjct: 958 QVVASIKHLHDQGIVHRDIKDENV---------------IVDS----------------- 985
Query: 458 NPEVKLIDFGSAVFYNEYHPPV-VSTRHYRAPEIVLGLGW-SFPCDIWSIACVLVELVTG 515
+ VKLIDFGSA + V V T Y APE++ G + P DIW++ +L ++
Sbjct: 986 HGFVKLIDFGSAAYIKSGPFDVFVGTMDYAAPEVLGGSSYKGKPQDIWALGVLLYTIIYK 1045
Query: 516 ESLY 519
E+ Y
Sbjct: 1046 ENPY 1049
>YMR139w [G] KOG0658 Glycogen synthase kinase-3
Length = 370
Score = 73.2 bits (178), Expect = 1e-12
Identities = 71/299 (23%), Positives = 129/299 (42%), Gaps = 51/299 (17%)
Query: 289 FQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKENDRSGQ 348
F +++G G+FG V + VA+K + R++ +++L I D
Sbjct: 39 FPTTEVVGHGSFGVVFATVIQETNEKVAIKKVLQDKRFKNRELEIMKMLSHINIID---- 94
Query: 349 YQCLLLREFFDYKN-----HICLVTDLYGRSVYDFMTNNGYARFPGSHVQA--IGKQLVR 401
L+ FF ++ ++ L+ + +S+Y + + + R P S ++ QL +
Sbjct: 95 -----LKYFFYERDSQDEIYLNLILEYMPQSLYQRLRHFVHQRTPMSRLEIKYYMFQLFK 149
Query: 402 SVCFLHDLG-IIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPE 460
S+ +LH + H D+KP+N+L+ ET
Sbjct: 150 SLNYLHHFANVCHRDIKPQNLLVDPETW-------------------------------S 178
Query: 461 VKLIDFGSAVFYNEYHPPV--VSTRHYRAPEIVLGL-GWSFPCDIWSIACVLVELVTGES 517
+KL DFGSA P V + +R+YRAPE++ G ++ DIWS CV+ EL+ G+
Sbjct: 179 LKLCDFGSAKQLKPTEPNVSYICSRYYRAPELIFGATNYTNQIDIWSSGCVMAELLLGQP 238
Query: 518 LYPIHENTEHMAMMQRINNEKFPKKMVEKMFFKVENKYGSIPTDLQTSVVKYFDRQTGE 576
++P + + + +I +++ +E+K+ I + V K D QT E
Sbjct: 239 MFPGESGIDQLVEIIKILGTPSKQEICSMNPNYMEHKFPQIKPIPLSRVFKKEDDQTVE 297
>At1g53510 [T] KOG0660 Mitogen-activated protein kinase
Length = 603
Score = 73.2 bits (178), Expect = 1e-12
Identities = 62/239 (25%), Positives = 113/239 (46%), Gaps = 34/239 (14%)
Query: 287 NRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKT---ELRVLQTIKEN 343
NR++ ++++G+G++G V D VA+K I V + A E+++L+ ++
Sbjct: 11 NRYRILEVIGKGSYGVVCAAIDTHTGEKVAIKKINDVFEHISDALRILREVKLLRLLRHP 70
Query: 344 DRSGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQLVRSV 403
D +L ++K+ I +V +L ++ + N H Q Q++R++
Sbjct: 71 DIVEIKSIMLPPSKREFKD-IYVVFELMESDLHQVIKAND--DLTREHHQFFLYQMLRAL 127
Query: 404 CFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKL 463
F+H + H DLKP+NIL + C + K+ G ++ N
Sbjct: 128 KFMHTANVYHRDLKPKNIL-ANANC---------------KLKVCDFGLARVAFN----- 166
Query: 464 IDFGSAVFYNEYHPPVVSTRHYRAPEIVLGL--GWSFPCDIWSIACVLVELVTGESLYP 520
D + VF+ +Y V+TR YRAPE+ ++ D+WSI C+ E++TG+ L+P
Sbjct: 167 -DTPTTVFWTDY----VATRWYRAPELCGSFFSKYTPAIDVWSIGCIFAEVLTGKPLFP 220
>7297680 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 297
Score = 73.2 bits (178), Expect = 1e-12
Identities = 62/251 (24%), Positives = 109/251 (42%), Gaps = 40/251 (15%)
Query: 289 FQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKENDRSGQ 348
F+ ++ +G+GT+G V K ++ L VA+K IR T +R + +KE
Sbjct: 4 FEKIEKIGEGTYGVVYKGRNRLTGQIVAMKKIRLESDDEGVPSTAIREISLLKELKHE-- 61
Query: 349 YQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSH-VQAIGKQLVRSVCFLH 407
+ L + +N I L+ + + +M + + S V++ Q+ ++ F H
Sbjct: 62 -NIVCLEDVLMEENRIYLIFEFLSMDLKKYMDSLPVDKHMESELVRSYLYQITSAILFCH 120
Query: 408 DLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKLIDFG 467
++H DLKP+N+LI D++ + +K+ DFG
Sbjct: 121 RRRVLHRDLKPQNLLI-DKSGL-------------------------------IKVADFG 148
Query: 468 SAVFYN---EYHPPVVSTRHYRAPEIVLGL-GWSFPCDIWSIACVLVELVTGESLYPIHE 523
+ + + T YRAPE++LG +S P DIWSI C+ E+ T + L+
Sbjct: 149 LGRSFGIPVRIYTHEIVTLWYRAPEVLLGSPRYSCPVDIWSIGCIFAEMATRKPLFQGDS 208
Query: 524 NTEHMAMMQRI 534
+ + M RI
Sbjct: 209 EIDQLFRMFRI 219
>YHR030c [T] KOG0660 Mitogen-activated protein kinase
Length = 484
Score = 72.8 bits (177), Expect = 2e-12
Identities = 64/267 (23%), Positives = 113/267 (41%), Gaps = 51/267 (19%)
Query: 282 DIFAKNRFQAMQLLGQGTFGKVVKCK--DYLNDITVAVKIIRAVDRYRQAAKTELRVLQT 339
D RFQ ++ +G G +G V + + D TVA+K + V K LR L+
Sbjct: 16 DFSVDKRFQLIKEIGHGAYGIVCSARFAEAAEDTTVAIKKVTNVFSKTLLCKRSLRELKL 75
Query: 340 IKENDRSGQYQCLLLREFFDYK----NHICLVTDLYGRSVYDFMTNNGYARFPGSHVQAI 395
++ CL + Y N + L +L ++ + + +H Q+
Sbjct: 76 LRHFRGHKNITCLYDMDIVFYPDGSINGLYLYEELMECDMHQIIKSG--QPLTDAHYQSF 133
Query: 396 GKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKI 455
Q++ + ++H ++H DLKP N+L+ + C
Sbjct: 134 TYQILCGLKYIHSADVLHRDLKPGNLLV-NADC--------------------------- 165
Query: 456 LINPEVKLIDFGSAVFYNE-------YHPPVVSTRHYRAPEIVLGL-GWSFPCDIWSIAC 507
++K+ DFG A Y+E + V+TR YRAPEI+L G++ D+WS C
Sbjct: 166 ----QLKICDFGLARGYSENPVENSQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSAGC 221
Query: 508 VLVELVTGESLYPIHENTEHMAMMQRI 534
+L E + G+ PI + +++ + +I
Sbjct: 222 ILAEFLGGK---PIFKGKDYVNQLNQI 245
>SPAC2F3.15 [D] KOG0600 Cdc2-related protein kinase
Length = 593
Score = 72.8 bits (177), Expect = 2e-12
Identities = 58/244 (23%), Positives = 109/244 (43%), Gaps = 47/244 (19%)
Query: 284 FAKNRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAV---DRYRQAAKTELRVLQTI 340
+ K ++ + +G+GT+GKV K + + VA+K IR D + E+++LQ +
Sbjct: 272 YPKPAYEKIDQIGEGTYGKVYKAINTVTGDLVALKRIRLEQEKDGFPITTVREVKILQRL 331
Query: 341 KENDRSGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQLV 400
+ + + L E K+ + +V + + + N+ PG+ ++ + KQ+
Sbjct: 332 RHKN------IVRLLEIMVEKSSVYMVFEYMDHDLTGVLLNSQLHFTPGN-IKHLSKQIF 384
Query: 401 RSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPE 460
++ +LH G++H D+K NIL+ + N +
Sbjct: 385 EALAYLHHRGVLHRDIKGSNILLNN--------------------------------NGD 412
Query: 461 VKLIDFGSAVF----YNEYHPPVVSTRHYRAPEIVLG-LGWSFPCDIWSIACVLVELVTG 515
+K DFG A F + + V T +R PE++LG + DIWS C+++EL TG
Sbjct: 413 LKFADFGLARFNTSSKSANYTNRVITLWFRPPELLLGETAYDTAVDIWSAGCIVMELFTG 472
Query: 516 ESLY 519
+ +
Sbjct: 473 KPFF 476
>At1g20930 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 315
Score = 72.8 bits (177), Expect = 2e-12
Identities = 64/268 (23%), Positives = 118/268 (43%), Gaps = 38/268 (14%)
Query: 283 IFAKNRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKE 342
+ A F+ ++ +G+GT+GKV + ++ + VA+K R + T LR + ++
Sbjct: 10 VSAMEAFEKLEKVGEGTYGKVYRAREKATGMIVALKKTRLHEDEEGVPPTTLREISILRM 69
Query: 343 NDRSGQYQCLL-LREFFDY--KNHICLVTDLYGRSVYDFMTNNGYA--RFPGSHVQAIGK 397
R L+ +++ + K + LV + + F+ + A P + V+ +
Sbjct: 70 LARDPHIVRLMDVKQGINKEGKTVLYLVFEYVDTDLKKFIRSFRQAGQNIPQNTVKCLMY 129
Query: 398 QLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILI 457
QL + + F H G++H DLKP N+L +D T K+A G +
Sbjct: 130 QLCKGMAFCHGHGVLHRDLKPHNLL---------------MDRKTMTLKIADLGLARAFT 174
Query: 458 NPEVKLIDFGSAVFYNEYHPPVVSTRHYRAPEIVLG-LGWSFPCDIWSIACVLVELVTGE 516
P K + + T YRAPE++LG +S D+WS+ C+ ELVT +
Sbjct: 175 LPMKK-------------YTHEILTLWYRAPEVLLGATHYSTGVDMWSVGCIFAELVTKQ 221
Query: 517 SLYPIHENTEHMAMMQRI----NNEKFP 540
+++ + + + R+ N E +P
Sbjct: 222 AIFAGDSELQQLLRIFRLLGTPNEEVWP 249
>At1g09840 [G] KOG0658 Glycogen synthase kinase-3
Length = 421
Score = 72.8 bits (177), Expect = 2e-12
Identities = 63/255 (24%), Positives = 114/255 (44%), Gaps = 57/255 (22%)
Query: 294 LLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKENDRSGQYQCLL 353
++G G+FG V + K VA+K + RY+ EL+++Q + + L
Sbjct: 88 VVGTGSFGMVFQAKCRETGEVVAIKKVLQDKRYKNR---ELQIMQMLDHPNAVA-----L 139
Query: 354 LREFFDYKNHICLVTDLYGRSVYDFM--TNNGYAR--------FPGSHVQAIGKQLVRSV 403
FF ++ ++Y V +F+ T N AR P +V+ Q+ R++
Sbjct: 140 KHSFFSRTDN----EEVYLNLVLEFVPETVNRVARSYSRTNQLMPLIYVKLYTYQICRAL 195
Query: 404 CFLHD-LGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVK 462
++H+ G+ H D+KP+N+L+ T ++K
Sbjct: 196 AYIHNSFGLCHRDIKPQNLLVNPHT-------------------------------HQLK 224
Query: 463 LIDFGSAVFYNEYHPPV--VSTRHYRAPEIVLGLG-WSFPCDIWSIACVLVELVTGESLY 519
+ DFGSA + P V + +R+YRAPE++ G ++ DIWS CV+ EL+ G+ L+
Sbjct: 225 ICDFGSAKVLVKGEPNVSYICSRYYRAPELIFGASEYTTAIDIWSTGCVMAELLLGQPLF 284
Query: 520 PIHENTEHMAMMQRI 534
P + + + ++
Sbjct: 285 PGESGVDQLVEIIKV 299
>YOR231w [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K)
Length = 508
Score = 72.4 bits (176), Expect = 2e-12
Identities = 77/301 (25%), Positives = 119/301 (38%), Gaps = 57/301 (18%)
Query: 233 DISNSASKSPSRFTKILKKS--PLLGSHQDKLRS---------MDRFKTDEEGHYVYQEN 281
D+SNS S ++S P+ S Q K S D + DE G + Y
Sbjct: 159 DLSNSVGSDFSNLISAYEQSSSPIKSSSQPKSSSESYIDLNSVRDVDQLDENG-WKYAN- 216
Query: 282 DIFAKNRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIK 341
K+R + + +LG+G G V KCK A+K+I ++ + K R LQ
Sbjct: 217 ---LKDRIETLGILGEGAGGSVSKCKLKNGSKIFALKVINTLNTDPEYQKQIFRELQF-- 271
Query: 342 ENDRSGQYQCLLLREFFDYKNHICLVTDLY--GRS---VYDFMTNNGYARFPGSHVQAIG 396
+Y F D +N + Y GRS +Y + G R + I
Sbjct: 272 NRSFQSEYIVRYYGMFTDDENSSIYIAMEYMGGRSLDAIYKNLLERG-GRISEKVLGKIA 330
Query: 397 KQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKIL 456
+ ++R + +LH+ +IH D+KP+NIL+ +
Sbjct: 331 EAVLRGLSYLHEKKVIHRDIKPQNILLNE------------------------------- 359
Query: 457 INPEVKLIDFG-SAVFYNEYHPPVVSTRHYRAPEIVLGLGWSFPCDIWSIACVLVELVTG 515
N +VKL DFG S N T Y APE + G +S D+WS+ ++E+ G
Sbjct: 360 -NGQVKLCDFGVSGEAVNSLATTFTGTSFYMAPERIQGQPYSVTSDVWSLGLTILEVANG 418
Query: 516 E 516
+
Sbjct: 419 K 419
>SPAC23A1.06c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 504
Score = 72.4 bits (176), Expect = 2e-12
Identities = 69/240 (28%), Positives = 113/240 (46%), Gaps = 26/240 (10%)
Query: 288 RFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVD---RYRQAAKTELRVLQTIKEND 344
++Q ++ LG G F +V K VAVK+IR + + RQ E+ +++ +K +
Sbjct: 64 KYQLIENLGDGAFSQVYKAYSIDRKEHVAVKVIRKYEMNKKQRQGVFKEVNIMRRVKHKN 123
Query: 345 RSGQYQCLLLREFFDYKNHICLVTDLY-GRSVYDFMTNNGYARFPGSHVQAIGKQLVRSV 403
+ L +F + ++ LV +L G ++ + N Y F + + I Q+ +V
Sbjct: 124 ------VVNLFDFVETEDFYHLVMELAEGGELFHQIVNFTY--FSENLARHIIIQVAEAV 175
Query: 404 CFLHDL-GIIHTDLKPENIL------ICDETCVEQSLPMEIIDSLTERRKLASGGKRKIL 456
LHD+ GI+H D+KPEN+L + + SL +D + +GG +IL
Sbjct: 176 KHLHDVCGIVHRDIKPENLLFQPIEYLPSQNYTPPSLEPNKLDEGMFLEGIGAGGIGRIL 235
Query: 457 INPEVKLIDFG-SAVFYNEYHPPVVSTRHYRAPEIVLGLGWSFPCDIWSIACVLVELVTG 515
I DFG S V +N T Y APEIV +S D+W++ CVL ++ G
Sbjct: 236 I------ADFGFSKVVWNSKTATPCGTVGYAAPEIVNDELYSKNVDMWAMGCVLHTMLCG 289
>Hs4502741 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 326
Score = 72.4 bits (176), Expect = 2e-12
Identities = 64/247 (25%), Positives = 111/247 (44%), Gaps = 48/247 (19%)
Query: 285 AKNRFQAMQLLGQGTFGKVVKCKDYLNDIT-VAVKIIRA--------VDRYRQAAKTELR 335
A +++ + +G+G +GKV K +D N VA+K +R + R+ A LR
Sbjct: 9 ADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAV--LR 66
Query: 336 VLQTIKENDRSGQYQ-CLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQA 394
L+T + + + C + R D + + LV + + + ++ P ++
Sbjct: 67 HLETFEHPNVVRLFDVCTVSRT--DRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKD 124
Query: 395 IGKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRK 454
+ QL+R + FLH ++H DLKP+NIL+ +SG
Sbjct: 125 MMFQLLRGLDFLHSHRVVHRDLKPQNILV-----------------------TSSG---- 157
Query: 455 ILINPEVKLIDFGSAVFYNEYH--PPVVSTRHYRAPEIVLGLGWSFPCDIWSIACVLVEL 512
++KL DFG A Y+ VV T YRAPE++L ++ P D+WS+ C+ E+
Sbjct: 158 -----QIKLADFGLARIYSFQMALTSVVVTLWYRAPEVLLQSSYATPVDLWSVGCIFAEM 212
Query: 513 VTGESLY 519
+ L+
Sbjct: 213 FRRKPLF 219
>Hs22057171 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 456
Score = 72.4 bits (176), Expect = 2e-12
Identities = 64/230 (27%), Positives = 105/230 (44%), Gaps = 41/230 (17%)
Query: 292 MQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVD-RYRQAAKTELRVLQTIKENDRSGQYQ 350
+ L G+G FG+V KC++ + +A KII+ + ++ K E+ V+ + D + Q
Sbjct: 177 LPLFGRGRFGQVHKCEETATGLKLAAKIIKTRGMKDKEEVKNEISVMNQL---DHANLIQ 233
Query: 351 CLLLREFFDYKNHICLVTDLY-GRSVYDFMTNNGYARFPGSHVQAIGKQLVRSVCFLHDL 409
L + F+ KN I LV + G ++D + + Y + + KQ+ + +H +
Sbjct: 234 ---LYDAFESKNDIVLVMEYVDGGELFDRIIDESYNLTELDTILFM-KQICEGIRHMHQM 289
Query: 410 GIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKLIDFGSA 469
I+H DLKPENIL CV + ++K+IDFG A
Sbjct: 290 YILHLDLKPENIL-----CVNRDA-------------------------KQIKIIDFGLA 319
Query: 470 VFYNEYHPPVVS--TRHYRAPEIVLGLGWSFPCDIWSIACVLVELVTGES 517
Y V+ T + APE+V SFP D+WS+ + L++G S
Sbjct: 320 RRYKPREKLKVNFGTPEFLAPEVVNYDFVSFPTDMWSVGVIAYMLLSGLS 369
>CE29020 [T] KOG0660 Mitogen-activated protein kinase
Length = 470
Score = 72.4 bits (176), Expect = 2e-12
Identities = 64/242 (26%), Positives = 104/242 (42%), Gaps = 28/242 (11%)
Query: 282 DIFAKNRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIK 341
D +F + LG+G +G V K D + TVA+K I D +R ++ + +
Sbjct: 6 DTHIHEKFDLQKRLGKGAYGIVWKAYDKRSRETVALKKI--FDAFRNPTDSQRTFREVMF 63
Query: 342 ENDRSGQYQCLLLREFF--DYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQL 399
+ + L F D I L + +++ + + H Q I QL
Sbjct: 64 LQEFGKHPNVIKLYNIFRADNDRDIYLAFEFMEADLHNVIKKGSILK--DVHKQYIMCQL 121
Query: 400 VRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINP 459
R++ FLH ++H DLKP N+L+ D C + + SL+ G K L
Sbjct: 122 FRAIRFLHSGNVLHRDLKPSNVLL-DADCRVKLADFGLARSLSSLEDYPEGQKMPDL--- 177
Query: 460 EVKLIDFGSAVFYNEYHPPVVSTRHYRAPEIVLGL-GWSFPCDIWSIACVLVELVTGESL 518
EY V+TR YR+PEI+L ++ D+WS+ C+L E++ G +L
Sbjct: 178 -------------TEY----VATRWYRSPEILLAAKRYTKGVDMWSLGCILAEMLIGRAL 220
Query: 519 YP 520
+P
Sbjct: 221 FP 222
>At3g14720 [T] KOG0660 Mitogen-activated protein kinase
Length = 586
Score = 72.4 bits (176), Expect = 2e-12
Identities = 62/239 (25%), Positives = 112/239 (45%), Gaps = 34/239 (14%)
Query: 287 NRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKT---ELRVLQTIKEN 343
NR++ ++++G+G++G V D VA+K I V + A E+++L+ ++
Sbjct: 11 NRYRILEVIGKGSYGVVCAAIDTQTGEKVAIKKINDVFEHVSDALRILREVKLLRLLRHP 70
Query: 344 DRSGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQLVRSV 403
D +L ++K+ I +V +L ++ + N H Q Q++R++
Sbjct: 71 DIVEIKSIMLPPSKREFKD-IYVVFELMESDLHQVIKAND--DLTREHHQFFLYQMLRAL 127
Query: 404 CFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKL 463
++H + H DLKP+NIL + C + K+ G ++ N
Sbjct: 128 KYMHTANVYHRDLKPKNIL-ANANC---------------KLKVCDFGLARVSFN----- 166
Query: 464 IDFGSAVFYNEYHPPVVSTRHYRAPEIVLGLGWSFP--CDIWSIACVLVELVTGESLYP 520
D + VF+ +Y V+TR YRAPE+ + DIWSI C+ E++TG+ L+P
Sbjct: 167 -DTPTTVFWTDY----VATRWYRAPELCGSFCSKYTPAIDIWSIGCIFAEVLTGKPLFP 220
>7303804 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 387
Score = 72.4 bits (176), Expect = 2e-12
Identities = 65/259 (25%), Positives = 117/259 (45%), Gaps = 40/259 (15%)
Query: 280 ENDIFAKNR----FQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELR 335
E ++F + R F+ + +G+G++G V + +D ++ VA+K +R + LR
Sbjct: 40 EQNLFGRCRPVSEFEKLNRVGEGSYGIVYRARDTRSNEIVALKKVRMDQEKDGLPISGLR 99
Query: 336 VLQTIKENDRSGQYQCLLLREFFDYKN--HICLVTDLYGRSVYDFMTNNGYARFPGSHVQ 393
+ +K+ + LRE K+ I LV D + + + N F S V+
Sbjct: 100 EIMILKQCHHEN---IVRLREVVVGKSLDSIFLVMDFCEQDLASVLDNMSQP-FTESEVK 155
Query: 394 AIGKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKR 453
I Q+++++ +LH +IH DLK N+L+ D+ C+ K+A G
Sbjct: 156 CITLQVLKALKYLHSRFMIHRDLKVSNLLMTDKGCI----------------KVADFGLA 199
Query: 454 KILINPEVKLIDFGSAVFYNEYHPPVVSTRHYRAPEIVLGL-GWSFPCDIWSIACVLVEL 512
++ NP + P + T YRAPE++LG + D+W+ C+L EL
Sbjct: 200 RMFSNPPKPM-------------TPQMVTLWYRAPELLLGCRTHTTAVDMWAFGCILGEL 246
Query: 513 VTGESLYPIHENTEHMAMM 531
+ G+ L P + + M+
Sbjct: 247 LLGKPLLPGNSEIAQLDMI 265
>YBL016w [T] KOG0660 Mitogen-activated protein kinase
Length = 353
Score = 72.0 bits (175), Expect = 3e-12
Identities = 63/238 (26%), Positives = 102/238 (42%), Gaps = 32/238 (13%)
Query: 289 FQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKT--ELRVLQTIKENDRS 346
FQ LLG+G +G V VA+K I D+ A +T E+++L+ K +
Sbjct: 13 FQLKSLLGEGAYGVVCSATHKPTGEIVAIKKIEPFDKPLFALRTLREIKILKHFKHENII 72
Query: 347 GQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQLVRSVCFL 406
+ + + F+ N + ++ +L ++ ++ H+Q Q +R+V L
Sbjct: 73 TIFN-IQRPDSFENFNEVYIIQELMQTDLHRVISTQ---MLSDDHIQYFIYQTLRAVKVL 128
Query: 407 HDLGIIHTDLKPENILI---CDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKL 463
H +IH DLKP N+LI CD + L I +S + +
Sbjct: 129 HGSNVIHRDLKPSNLLINSNCDLKVCDFGLARIIDESAADNSE----------------- 171
Query: 464 IDFGSAVFYNEYHPPVVSTRHYRAPEIVL-GLGWSFPCDIWSIACVLVELVTGESLYP 520
G EY V+TR YRAPE++L +S D+WS C+L EL ++P
Sbjct: 172 -PTGQQSGMTEY----VATRWYRAPEVMLTSAKYSRAMDVWSCGCILAELFLRRPIFP 224
>SPAC31G5.09c [T] KOG0660 Mitogen-activated protein kinase
Length = 372
Score = 72.0 bits (175), Expect = 3e-12
Identities = 60/235 (25%), Positives = 108/235 (45%), Gaps = 33/235 (14%)
Query: 289 FQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKT--ELRVLQTIKENDRS 346
++ + L+GQG +G V + + VAVK I + +T E+++L+ + +
Sbjct: 39 YEMINLIGQGAYGVVCAALHKPSGLKVAVKKIHPFNHPVFCLRTLREIKLLRHFRHENII 98
Query: 347 GQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQLVRSVCFL 406
L + + ++ + +V +L +Y + + + H Q Q++R++ +
Sbjct: 99 SILDILPPPSYQELED-VYIVQELMETDLYRVIRSQPLS---DDHCQYFTYQILRALKAM 154
Query: 407 HDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKLIDF 466
H G++H DLKP N+L+ + +++ D R A GG NP
Sbjct: 155 HSAGVVHRDLKPSNLLL------NANCDLKVADFGLARSTTAQGG------NPG------ 196
Query: 467 GSAVFYNEYHPPVVSTRHYRAPEIVLGL-GWSFPCDIWSIACVLVELVTGESLYP 520
F EY V+TR YRAPEI+L +S D+WS C+L E+++ L+P
Sbjct: 197 ----FMTEY----VATRWYRAPEIMLSFREYSKAIDLWSTGCILAEMLSARPLFP 243
>Hs7657526 [T] KOG0603 Ribosomal protein S6 kinase
Length = 745
Score = 72.0 bits (175), Expect = 3e-12
Identities = 60/254 (23%), Positives = 114/254 (44%), Gaps = 40/254 (15%)
Query: 289 FQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKENDRSGQ 348
++ + +G G++ +C ++ AVKII D+ ++ E+ +L R GQ
Sbjct: 426 YELKEDIGVGSYSVCKRCIHATTNMEFAVKII---DKSKRDPSEEIEILM------RYGQ 476
Query: 349 YQCLL-LREFFDYKNHICLVTDLY--GRSVYDFMTNNGYARFPGSHVQAIGKQLVRSVCF 405
+ ++ L++ FD ++ LVTDL G + + ++ S + + + ++V +
Sbjct: 477 HPNIITLKDVFDDGRYVYLVTDLMKGGELLDRILKQKCFSEREASDILYV---ISKTVDY 533
Query: 406 LHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKLID 465
LH G++H DLKP NIL DE+ S+ + + R G+ +L+ P
Sbjct: 534 LHCQGVVHRDLKPSNILYMDESASADSIRICDFGFAKQLR-----GENGLLLTP------ 582
Query: 466 FGSAVFYNEYHPPVVSTRHYRAPEIVLGLGWSFPCDIWSIACVLVELVTGESLYPIHENT 525
T ++ APE+++ G+ CDIWS+ + ++ G + + N
Sbjct: 583 --------------CYTANFVAPEVLMQQGYDAACDIWSLGVLFYTMLAGYTPFANGPND 628
Query: 526 EHMAMMQRINNEKF 539
++ RI N KF
Sbjct: 629 TPEEILLRIGNGKF 642
Score = 57.4 bits (137), Expect = 7e-08
Identities = 67/264 (25%), Positives = 107/264 (40%), Gaps = 44/264 (16%)
Query: 275 HYVYQENDIFAKNRFQAMQLLGQGTFGKVVKCKDYLNDIT---VAVKIIRAVD---RYRQ 328
H+V + + +F+ +++LGQG+FGKV + A+K+++ R R
Sbjct: 59 HHVKEGYEKADPAQFELLKVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLKKASLKVRDRV 118
Query: 329 AAKTELRVLQTIKENDRSGQYQCLLLREFFDYKNHICLVTD-LYGRSVYDFMTNNGYARF 387
K E +L + + L F + + L+ D L G V+ ++ F
Sbjct: 119 RTKMERDILVEVNHPF------IVKLHYAFQTEGKLYLILDFLRGGDVFTRLSKE--VLF 170
Query: 388 PGSHVQAIGKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKL 447
V+ +L ++ LH LGI++ DLKPENIL+ DE KL
Sbjct: 171 TEEDVKFYLAELALALDHLHQLGIVYRDLKPENILL-DE---------------IGHIKL 214
Query: 448 ASGGKRKILINPEVKLIDFGSAVFYNEYHPPVVSTRHYRAPEIVLGLGWSFPCDIWSIAC 507
G K ++ E K F T Y APE+V G S D WS
Sbjct: 215 TDFGLSKESVDQEKKAYSF-------------CGTVEYMAPEVVNRRGHSQSADWWSYGV 261
Query: 508 VLVELVTGESLYPIHENTEHMAMM 531
++ E++TG + + E M M+
Sbjct: 262 LMFEMLTGTLPFQGKDRNETMNMI 285
>Hs14110390 [D] KOG0600 Cdc2-related protein kinase
Length = 1452
Score = 72.0 bits (175), Expect = 3e-12
Identities = 75/319 (23%), Positives = 131/319 (40%), Gaps = 71/319 (22%)
Query: 249 LKKSPLLGSHQDKLRSMDRFKTDEEGHYVYQENDI----FAKNRFQAMQLLGQGTFGKVV 304
L KSP +L S R K + +E DI ++F + ++G+GT+G+V
Sbjct: 661 LSKSPEEKKTTTQLHSKRRPKICGPRYGETKEKDIDWGKLCVDKFDIIGIIGEGTYGQVY 720
Query: 305 KCKDYLNDITVAVKIIRAVDRYRQA----AKTELRVLQTIKENDRSGQYQCLLLRE---- 356
K +D VA+K +R +D ++ A E+++L+ + + + +E
Sbjct: 721 KARDKDTGEMVALKKVR-LDNEKEGFPITAIREIKILRQLTHQSIINMKEIVTDKEDALD 779
Query: 357 ----------FFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQLVRSVCFL 406
F+Y +H DL G + +G F +H+++ +QL+ + +
Sbjct: 780 FKKDKGAFYLVFEYMDH-----DLMG------LLESGLVHFNENHIKSFMRQLMEGLDYC 828
Query: 407 HDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKLIDF 466
H +H D+K NIL+ + ++KL DF
Sbjct: 829 HKKNFLHRDIKCSNILLNN--------------------------------RGQIKLADF 856
Query: 467 GSAVFYN--EYHPPV--VSTRHYRAPEIVLGLGWSFPC-DIWSIACVLVELVTGESLYPI 521
G A Y+ E P V T YR PE++LG P D+WS C+L EL T + ++
Sbjct: 857 GLARLYSSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQA 916
Query: 522 HENTEHMAMMQRINNEKFP 540
++ + ++ RI P
Sbjct: 917 NQELAQLELISRICGSPCP 935
>Hs14110387 [D] KOG0600 Cdc2-related protein kinase
Length = 1512
Score = 72.0 bits (175), Expect = 3e-12
Identities = 75/319 (23%), Positives = 131/319 (40%), Gaps = 71/319 (22%)
Query: 249 LKKSPLLGSHQDKLRSMDRFKTDEEGHYVYQENDI----FAKNRFQAMQLLGQGTFGKVV 304
L KSP +L S R K + +E DI ++F + ++G+GT+G+V
Sbjct: 661 LSKSPEEKKTTTQLHSKRRPKICGPRYGETKEKDIDWGKLCVDKFDIIGIIGEGTYGQVY 720
Query: 305 KCKDYLNDITVAVKIIRAVDRYRQA----AKTELRVLQTIKENDRSGQYQCLLLRE---- 356
K +D VA+K +R +D ++ A E+++L+ + + + +E
Sbjct: 721 KARDKDTGEMVALKKVR-LDNEKEGFPITAIREIKILRQLTHQSIINMKEIVTDKEDALD 779
Query: 357 ----------FFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQLVRSVCFL 406
F+Y +H DL G + +G F +H+++ +QL+ + +
Sbjct: 780 FKKDKGAFYLVFEYMDH-----DLMG------LLESGLVHFNENHIKSFMRQLMEGLDYC 828
Query: 407 HDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKLIDF 466
H +H D+K NIL+ + ++KL DF
Sbjct: 829 HKKNFLHRDIKCSNILLNN--------------------------------RGQIKLADF 856
Query: 467 GSAVFYN--EYHPPV--VSTRHYRAPEIVLGLGWSFPC-DIWSIACVLVELVTGESLYPI 521
G A Y+ E P V T YR PE++LG P D+WS C+L EL T + ++
Sbjct: 857 GLARLYSSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQA 916
Query: 522 HENTEHMAMMQRINNEKFP 540
++ + ++ RI P
Sbjct: 917 NQELAQLELISRICGSPCP 935
>CE08727 [G] KOG0658 Glycogen synthase kinase-3
Length = 367
Score = 72.0 bits (175), Expect = 3e-12
Identities = 72/286 (25%), Positives = 121/286 (42%), Gaps = 52/286 (18%)
Query: 288 RFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKENDRSG 347
+F +QL+G G+FG V K ND +A+K I+ DR++ R L + E D
Sbjct: 36 QFTNLQLIGTGSFGAVYKAVLRENDEPIAIKKIKVDDRFKS------RELTIMHEMDHPN 89
Query: 348 QYQCLLLREFFDYKNHICLVTDLYGRSV----YDFMTNNGYARFPGSHVQAIGKQLVRSV 403
+ LL +N + V + + + F N+ + P ++ QL+R +
Sbjct: 90 IIR-LLYYYVMQQENCLNFVMEFMPKDLAYVHRQFAHND--KQMPAYSIKLYMFQLLRGI 146
Query: 404 CFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKL 463
FLH I+H D+KP+N+L+ DE+ N +K+
Sbjct: 147 GFLHLHNIVHRDIKPKNLLV-DES------------------------------NGILKI 175
Query: 464 IDFGSAVFYNEYHPPV--VSTRHYRAPEIVLG-LGWSFPCDIWSIACVLVELVTGESLYP 520
DFGSA + P + + +R+YRAPE++ G + D WS+ V+ EL+ ++
Sbjct: 176 CDFGSAKRLEKNEPNITYICSRYYRAPELIFGSKNYDTSIDTWSVGTVVGELLHNSPIFL 235
Query: 521 IHENTEHMAMMQRINNEKFPKKMVEKMFFKVENKYGSIPTDLQTSV 566
+ +A+ + + M K +Y IP D T V
Sbjct: 236 ADSAVDILALQIKAFGTPSKEDMA-----KWNYEYVHIPYDTITGV 276
>CE06762 [T] KOG0660 Mitogen-activated protein kinase
Length = 367
Score = 72.0 bits (175), Expect = 3e-12
Identities = 62/245 (25%), Positives = 101/245 (40%), Gaps = 24/245 (9%)
Query: 289 FQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKENDRSGQ 348
+ A + +G G +G V K D N VA+K I AK LR ++ ++E
Sbjct: 57 YLAEENVGAGAYGVVCKAMDTRNKKQVAIKKIPRAFTAHTLAKRSLREVRILRELLHENI 116
Query: 349 YQCL-LLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQLVRSVCFLH 407
L + + I LV DL ++ + + H Q QL+R + +LH
Sbjct: 117 IAVLDMFTAEGAHGKDIYLVMDLMETDLHQILHSR--QTLMEQHFQYFFYQLLRGLKYLH 174
Query: 408 DLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKLIDFG 467
GIIH DLKP N+L+ + + ++A G + + D
Sbjct: 175 SAGIIHRDLKPSNLLLNGDCLL----------------RIADFGMARAYASASTVRDDAN 218
Query: 468 SAVFYNEYHPPVVSTRHYRAPEIVLGL-GWSFPCDIWSIACVLVELVTGESLYPIHENTE 526
+Y VSTR YRAPEI+ + + D+WS C+ E++ L+P ++
Sbjct: 219 VGGHMTQY----VSTRWYRAPEILFSMVEYDTKVDLWSAGCIFAEMLLRRQLFPGKDSVS 274
Query: 527 HMAMM 531
+ M+
Sbjct: 275 QIKMI 279
>At3g44850 [T] KOG1290 Serine/threonine protein kinase
Length = 534
Score = 72.0 bits (175), Expect = 3e-12
Identities = 46/156 (29%), Positives = 80/156 (50%), Gaps = 7/156 (4%)
Query: 274 GHYVYQENDIFAKNRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTE 333
G++ + D F + LG G F V D VA+K+ ++ Y +AA E
Sbjct: 30 GYHTVRVGDTFKNGAYVIQSKLGWGHFSTVWLAWDTQESRYVALKVQKSAQHYTEAAMDE 89
Query: 334 LRVLQTIKENDRSGQYQCLL-LREFFDYKN----HICLVTDLYGRSVYDFMTNNGYARFP 388
+++L+ I E D SG +C++ L + F + H+C+V + G ++ + + Y P
Sbjct: 90 IKILKQIAEGD-SGDKKCVVKLLDHFKHTGPNGKHVCMVFEYLGDNLLSVIKYSDYRGVP 148
Query: 389 GSHVQAIGKQLVRSVCFLH-DLGIIHTDLKPENILI 423
V+ + ++ + +LH +L IIHTDLKPEN+L+
Sbjct: 149 LHMVKELCFHILVGLDYLHRELSIIHTDLKPENVLL 184
Score = 67.0 bits (162), Expect = 9e-11
Identities = 67/251 (26%), Positives = 106/251 (41%), Gaps = 77/251 (30%)
Query: 445 RKLASGGKRKIL--INPEVKLIDFGSAVFYNEYHPPVVSTRHYRAPEIVLGLGWSFPCDI 502
R+ + ++K+L I + KL+DFG+A + + + TR YR PE+VLG +S D+
Sbjct: 303 RRGSRSTRQKLLSDIECKCKLVDFGNACWTYKQFTSDIQTRQYRCPEVVLGSKYSTSADM 362
Query: 503 WSIACVLVELVTGESLYPIH------ENTEHMAMMQRINNEKFPKKMVEKMFFKVENKYG 556
WS AC+ EL TG+ L+ H + +H+A+M + P+K+ + +Y
Sbjct: 363 WSFACICFELATGDVLFDPHSGENYDRDEDHLALMMELLG-MMPRKIA------LGGRYS 415
Query: 557 SIPTDLQTSVVKYFDRQTGELRWPLRNSKGQVITKEKSWKRILATCDRLDVFISKKLQMD 616
+F+RQ GELR I + + W ISK L+
Sbjct: 416 R----------DFFNRQ-GELRH---------IRRLRFWP------------ISKVLKEK 443
Query: 617 YGSWLEIHWDMQLEDNWRLILSKNIDSRNIDKNVFMFWYYFVDLCRKMFEFDPTKRITAK 676
Y D +D +K++ D + EF P KR TA
Sbjct: 444 Y--------DFSEQD------AKDMS----------------DFLVTILEFVPEKRPTAA 473
Query: 677 EVIEHEWFNIG 687
+ ++H WFN G
Sbjct: 474 QCLKHPWFNPG 484
>Hs4759050 [T] KOG0603 Ribosomal protein S6 kinase
Length = 740
Score = 71.6 bits (174), Expect = 4e-12
Identities = 67/274 (24%), Positives = 126/274 (45%), Gaps = 49/274 (17%)
Query: 275 HYVYQE---NDIFAKNRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAK 331
H + Q+ N I + ++ + +G G++ +C ++ AVKII D+ ++
Sbjct: 405 HSIVQQLHRNSIQFTDGYEVKEDIGVGSYSVCKRCIHKATNMEFAVKII---DKSKRDPT 461
Query: 332 TELRVLQTIKENDRSGQYQCLL-LREFFDYKNHICLVTDLY-GRSVYDFMTNNGYARFPG 389
E+ +L R GQ+ ++ L++ +D ++ +VT+L G + D + + F
Sbjct: 462 EEIEILL------RYGQHPNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKF--FSE 513
Query: 390 SHVQAIGKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLAS 449
A+ + ++V +LH G++H DLKP NIL DE S
Sbjct: 514 REASAVLFTITKTVEYLHAQGVVHRDLKPSNILYVDE----------------------S 551
Query: 450 GGKRKILINPE-VKLIDFGSAVFYNEYHPPVVS---TRHYRAPEIVLGLGWSFPCDIWSI 505
G NPE +++ DFG A + +++ T ++ APE++ G+ CDIWS+
Sbjct: 552 G-------NPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDAACDIWSL 604
Query: 506 ACVLVELVTGESLYPIHENTEHMAMMQRINNEKF 539
+L ++TG + + + ++ RI + KF
Sbjct: 605 GVLLYTMLTGYTPFANGPDDTPEEILARIGSGKF 638
Score = 63.9 bits (154), Expect = 8e-10
Identities = 66/262 (25%), Positives = 113/262 (42%), Gaps = 40/262 (15%)
Query: 275 HYVYQENDIFAKNRFQAMQLLGQGTFGKVVKCKDYLNDIT---VAVKIIR-AVDRYRQAA 330
H+V + ++ ++F+ +++LGQG+FGKV K A+K+++ A + R
Sbjct: 54 HHVKEGHEKADPSQFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRV 113
Query: 331 KTELRVLQTIKENDRSGQYQCLLLREFFDYKNHICLVTD-LYGRSVYDFMTNNGYARFPG 389
+T++ ++ N + L F + + L+ D L G ++ ++ F
Sbjct: 114 RTKMERDILVEVNHPF----IVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKE--VMFTE 167
Query: 390 SHVQAIGKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLAS 449
V+ +L ++ LH LGII+ DLKPENIL+ +E + KL
Sbjct: 168 EDVKFYLAELALALDHLHSLGIIYRDLKPENILLDEEGHI----------------KLTD 211
Query: 450 GGKRKILINPEVKLIDFGSAVFYNEYHPPVVSTRHYRAPEIVLGLGWSFPCDIWSIACVL 509
G K I+ E K F T Y APE+V G + D WS ++
Sbjct: 212 FGLSKESIDHEKKAYSF-------------CGTVEYMAPEVVNRRGHTQSADWWSFGVLM 258
Query: 510 VELVTGESLYPIHENTEHMAMM 531
E++TG + + E M M+
Sbjct: 259 FEMLTGTLPFQGKDRKETMTMI 280
>Hs4506095 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 384
Score = 71.6 bits (174), Expect = 4e-12
Identities = 61/262 (23%), Positives = 111/262 (42%), Gaps = 42/262 (16%)
Query: 265 MDRFKTDEEGHYVYQENDIFAK-NRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAV 323
M R K D + V + F R+Q ++ +G G G V D + + VA+K +
Sbjct: 1 MSRSKRDNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRP 60
Query: 324 DRYRQAAKT---ELRVLQTIKENDRSGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMT 380
+ + AK EL +++ + + G ++ + + +V +L ++ +
Sbjct: 61 FQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ 120
Query: 381 NNGYARFPGSHVQAIGKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDS 440
+ + Q++ + LH GIIH DLKP NI++ + +
Sbjct: 121 ----MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTL----------- 165
Query: 441 LTERRKLASGGKRKILINPEVKLIDFGSA--VFYNEYHPPVVSTRHYRAPEIVLGLGWSF 498
K++DFG A + P V TR+YRAPE++LG+G+
Sbjct: 166 ---------------------KILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGYKE 204
Query: 499 PCDIWSIACVLVELVTGESLYP 520
D+WS+ C++ E+V + L+P
Sbjct: 205 NVDLWSVGCIMGEMVCHKILFP 226
>Hs20986523 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 427
Score = 71.6 bits (174), Expect = 4e-12
Identities = 61/262 (23%), Positives = 111/262 (42%), Gaps = 42/262 (16%)
Query: 265 MDRFKTDEEGHYVYQENDIFAK-NRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAV 323
M R K D + V + F R+Q ++ +G G G V D + + VA+K +
Sbjct: 1 MSRSKRDNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRP 60
Query: 324 DRYRQAAKT---ELRVLQTIKENDRSGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMT 380
+ + AK EL +++ + + G ++ + + +V +L ++ +
Sbjct: 61 FQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ 120
Query: 381 NNGYARFPGSHVQAIGKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDS 440
+ + Q++ + LH GIIH DLKP NI++ + +
Sbjct: 121 ----MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTL----------- 165
Query: 441 LTERRKLASGGKRKILINPEVKLIDFGSA--VFYNEYHPPVVSTRHYRAPEIVLGLGWSF 498
K++DFG A + P V TR+YRAPE++LG+G+
Sbjct: 166 ---------------------KILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGYKE 204
Query: 499 PCDIWSIACVLVELVTGESLYP 520
D+WS+ C++ E+V + L+P
Sbjct: 205 NVDLWSVGCIMGEMVCHKILFP 226
>CE29073 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 700
Score = 71.6 bits (174), Expect = 4e-12
Identities = 63/250 (25%), Positives = 113/250 (45%), Gaps = 43/250 (17%)
Query: 289 FQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKENDRSGQ 348
++ + LG+GT+ V + + L + VA+K IR +++ A T +R + ++ +
Sbjct: 361 YEKLDKLGEGTYATVFRGRSILTNKFVALKEIR-LEQEEGAPCTAIREVSLLRNLRHAN- 418
Query: 349 YQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQLVRSVCFLHD 408
+ L + + LV + R + +M + A ++++ QL+R + + H
Sbjct: 419 --VVTLHDIIHTDRLLTLVFEYVDRDLKQYMDSCNNA-MQMNNIRLFLYQLLRGLAYCHQ 475
Query: 409 LGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKLIDFGS 468
++H DLKP+N+LI A G E+KL DFG
Sbjct: 476 RRVLHRDLKPQNLLI-----------------------TAKG---------ELKLADFGL 503
Query: 469 A----VFYNEYHPPVVSTRHYRAPEIVLG-LGWSFPCDIWSIACVLVELVTGESLYPIHE 523
A V Y VV T YR P+++LG +S D+W + C+L E++ G +L+P
Sbjct: 504 ARAKSVPTKTYSNEVV-TLWYRPPDVLLGSTDYSTHIDMWGVGCILFEMIAGRALFPGGT 562
Query: 524 NTEHMAMMQR 533
TE + ++ R
Sbjct: 563 PTEQLGLIFR 572
>CE06779 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 577
Score = 71.6 bits (174), Expect = 4e-12
Identities = 63/250 (25%), Positives = 113/250 (45%), Gaps = 43/250 (17%)
Query: 289 FQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKENDRSGQ 348
++ + LG+GT+ V + + L + VA+K IR +++ A T +R + ++ +
Sbjct: 238 YEKLDKLGEGTYATVFRGRSILTNKFVALKEIR-LEQEEGAPCTAIREVSLLRNLRHAN- 295
Query: 349 YQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQLVRSVCFLHD 408
+ L + + LV + R + +M + A ++++ QL+R + + H
Sbjct: 296 --VVTLHDIIHTDRLLTLVFEYVDRDLKQYMDSCNNA-MQMNNIRLFLYQLLRGLAYCHQ 352
Query: 409 LGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKLIDFGS 468
++H DLKP+N+LI A G E+KL DFG
Sbjct: 353 RRVLHRDLKPQNLLI-----------------------TAKG---------ELKLADFGL 380
Query: 469 A----VFYNEYHPPVVSTRHYRAPEIVLG-LGWSFPCDIWSIACVLVELVTGESLYPIHE 523
A V Y VV T YR P+++LG +S D+W + C+L E++ G +L+P
Sbjct: 381 ARAKSVPTKTYSNEVV-TLWYRPPDVLLGSTDYSTHIDMWGVGCILFEMIAGRALFPGGT 439
Query: 524 NTEHMAMMQR 533
TE + ++ R
Sbjct: 440 PTEQLGLIFR 449
>7296450 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 769
Score = 71.6 bits (174), Expect = 4e-12
Identities = 59/230 (25%), Positives = 92/230 (39%), Gaps = 37/230 (16%)
Query: 289 FQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKENDRSGQ 348
++ LLG+G F V K + VA+K+I + Q RV Q ++ + R
Sbjct: 14 YEVQHLLGKGGFATVYKARCLHTHQDVAIKMIDK--KLIQGTGLTNRVRQEVEIHSRLKH 71
Query: 349 YQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQLVRSVCFLHD 408
L L FF N++ LV +L N+ F + +I KQ+V + +LH
Sbjct: 72 PSVLQLYTFFQDANYVYLVLELAHNGELHRYMNHIARPFTETEAASILKQVVAGLLYLHS 131
Query: 409 LGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKLIDFGS 468
I+H D+ N+L+ E VK+ DFG
Sbjct: 132 HNIMHRDISLSNLLLSREM--------------------------------HVKIADFGL 159
Query: 469 AVFY---NEYHPPVVSTRHYRAPEIVLGLGWSFPCDIWSIACVLVELVTG 515
A +E H + T +Y +PE+V P D+WS+ C+L L+ G
Sbjct: 160 ATQLKRPDERHMTMCGTPNYISPEVVSRTSHGLPADVWSVGCMLYTLLVG 209
>YFR014c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 446
Score = 71.2 bits (173), Expect = 5e-12
Identities = 72/299 (24%), Positives = 125/299 (41%), Gaps = 38/299 (12%)
Query: 260 DKLRSMDRFKTDEEGHYVY-QENDIFAKNRFQAMQLLGQGTFGKVVKCKDYLNDITVAVK 318
+K S + + D EG + Q K ++ + LG GTFG V + K+ VAVK
Sbjct: 7 EKESSPKQTEEDSEGKMAHVQPASYVNKKKYVFGKTLGAGTFGVVRQAKNTETGEDVAVK 66
Query: 319 IIRAVDRYRQAAKTELRVL-QTIKENDRSGQYQCLLLREFFDYKNHICLVTDLY-GRSVY 376
I+ + + + K +L L + R + +++F+ K+ ++T L G ++
Sbjct: 67 IL--IKKALKGNKVQLEALYDELDILQRLHHPNIVAFKDWFESKDKFYIITQLAKGGELF 124
Query: 377 DFMTNNGYARFPGSHVQAIGKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPME 436
D + G +F I +++ +V ++H I+H DLKPEN+L D++ P+
Sbjct: 125 DRILKKG--KFTEEDAVRILVEILSAVKYMHSQNIVHRDLKPENLLYIDKS---DESPLV 179
Query: 437 IID-SLTERRKLASGGKRKILINPEVKLIDFGSAVFYNEYHPPVVSTRHYRAPEIVLGLG 495
+ D + +R K ++L P L Y APE++ G
Sbjct: 180 VADFGIAKRLK----SDEELLYKPAGSL--------------------GYVAPEVLTQDG 215
Query: 496 WSFPCDIWSIACVLVELVTGESLYPIHENTEHMAMMQRINNEKFPKKMVEKMFFKVENK 554
PCDIWSI + L+ G S + + + ++P K + V NK
Sbjct: 216 HGKPCDIWSIGVITYTLLCGYSAFRAERVQD---FLDECTTGEYPVKFHRPYWDSVSNK 271
>At3g13530 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 1368
Score = 71.2 bits (173), Expect = 5e-12
Identities = 63/258 (24%), Positives = 110/258 (42%), Gaps = 42/258 (16%)
Query: 287 NRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKENDRS 346
N++ +G+G +G+V K D N VA+K + + ++ T ++ + +K +
Sbjct: 18 NKYMLGDEIGKGAYGRVYKGLDLENGDFVAIKQVSLENIVQEDLNTIMQEIDLLKNLNHK 77
Query: 347 GQYQCLLLREFFDYKNHICLVTD-LYGRSVYDFMTNNGYARFPGSHVQAIGKQLVRSVCF 405
+ L + K H+ ++ + + S+ + + N + FP S V Q++ + +
Sbjct: 78 NIVKYLGSSKT---KTHLHIILEYVENGSLANIIKPNKFGPFPESLVAVYIAQVLEGLVY 134
Query: 406 LHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKLID 465
LH+ G+IH D+K NIL E VKL D
Sbjct: 135 LHEQGVIHRDIKGANILTTKEGL--------------------------------VKLAD 162
Query: 466 FGSAVFYNEYH---PPVVSTRHYRAPEIVLGLGWSFPCDIWSIACVLVELVTGESLYPIH 522
FG A NE VV T ++ APE++ G DIWS+ C ++EL+T P +
Sbjct: 163 FGVATKLNEADVNTHSVVGTPYWMAPEVIEMSGVCAASDIWSVGCTVIELLT---CVPPY 219
Query: 523 ENTEHMAMMQRINNEKFP 540
+ + M + RI + P
Sbjct: 220 YDLQPMPALFRIVQDDNP 237
>YOL128c [G] KOG0658 Glycogen synthase kinase-3
Length = 375
Score = 70.9 bits (172), Expect = 6e-12
Identities = 75/324 (23%), Positives = 142/324 (43%), Gaps = 76/324 (23%)
Query: 248 ILKKSPLLGSHQDKLRSMDRFKTDEEGHYVYQENDIFAKNRFQAMQL------LGQGTFG 301
+LK + + GS+ +++ + E+ HY + ++ + KNR ++ +G G+FG
Sbjct: 1 MLKVNNVFGSNPNRMTKL------EDEHY-FIDDIVSIKNRQKSKMYVREGKRIGHGSFG 53
Query: 302 KVVKCKDYLNDIT-VAVKIIRAVDRYRQAAKTELRVLQTIKENDRSGQYQCLLLREFFDY 360
V + N I + I+ V + + EL +LQ I+ + L+ EFF +
Sbjct: 54 TVTQSILSSNSIEWLGPYAIKRVVKSPKVQSLELEILQNIRHPN-------LVTLEFF-F 105
Query: 361 KNHICLVTD---LYGRS-------------VYDFMTNNGYARFPGSHVQAIGKQLVRSVC 404
++H C D LY ++ ++++ N ++ P H++ Q++R++
Sbjct: 106 ESH-CTTKDGGHLYQKNFVMEYIPQTLSSEIHEYFDNG--SKMPTKHIKLYTFQILRALL 162
Query: 405 FLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKLI 464
LH + I H DLKP NILI + + K+
Sbjct: 163 TLHSMSICHGDLKPSNILIIPSSGI-------------------------------AKVC 191
Query: 465 DFGSA--VFYNEYHPPVVSTRHYRAPEIVL-GLGWSFPCDIWSIACVLVELVTGESLYPI 521
DFGSA + N +R YRAPE++L ++ DIWS+ C++ E++ G+ L+
Sbjct: 192 DFGSAQRLDDNTELKTYFCSRFYRAPELLLNSKDYTTQIDIWSLGCIIGEMIKGQPLFKG 251
Query: 522 HENTEHMAMMQRINNEKFPKKMVE 545
+ + ++ +FPK ++
Sbjct: 252 DSANSQLEEIAKLLG-RFPKSSIK 274
>Hs14196445 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 476
Score = 70.9 bits (172), Expect = 6e-12
Identities = 69/265 (26%), Positives = 113/265 (42%), Gaps = 44/265 (16%)
Query: 265 MDRFKTDEEGHYVYQENDIFAKNRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVD 324
M R + D+ + Q +I + F M++LG G F +V K L A+K I+
Sbjct: 1 MGRKEEDDCSSWKKQTTNI--RKTFIFMEVLGSGAFSEVFLVKQRLTGKLFALKCIKKSP 58
Query: 325 RYRQAA-KTELRVLQTIKENDRSGQYQCLLLREFFDYKNHICLVTDLY-GRSVYDFMTNN 382
+R ++ + E+ VL+ IK + + L + ++ H LV L G ++D +
Sbjct: 59 AFRDSSLENEIAVLKKIKHEN------IVTLEDIYESTTHYYLVMQLVSGGELFDRILER 112
Query: 383 GYARFPGSHVQAIGKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLT 442
G + + +Q++ +V +LH+ GI+H DLKPEN+L P E
Sbjct: 113 GV--YTEKDASLVIQQVLSAVKYLHENGIVHRDLKPENLLYL--------TPEE------ 156
Query: 443 ERRKLASGGKRKILINPEVKLIDFG-SAVFYNEYHPPVVSTRHYRAPEIVLGLGWSFPCD 501
N ++ + DFG S + N T Y APE++ +S D
Sbjct: 157 ---------------NSKIMITDFGLSKMEQNGIMSTACGTPGYVAPEVLAQKPYSKAVD 201
Query: 502 IWSIACVLVELVTGESLYPIHENTE 526
WSI + L+ G P +E TE
Sbjct: 202 CWSIGVITYILLCGYP--PFYEETE 224
>At4g00720 [G] KOG0658 Glycogen synthase kinase-3
Length = 472
Score = 70.9 bits (172), Expect = 6e-12
Identities = 64/258 (24%), Positives = 114/258 (43%), Gaps = 53/258 (20%)
Query: 289 FQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKENDRSGQ 348
+ A +++G G+FG V + K VA+K + RY+ R LQ ++ D
Sbjct: 138 YMAQRVVGTGSFGVVFQAKCLETGEQVAIKKVLQDKRYKN------RELQIMRLQDHPNV 191
Query: 349 YQCLLLREFFDYKN----HICLVTDLYGRSVYDFMTNNGYARF----PGSHVQAIGKQLV 400
+ L FF + ++ LV + +VY + Y + P VQ Q+
Sbjct: 192 VR--LRHSFFSTTDKDELYLNLVLEYVPETVY--RASKHYTKMNQHMPIIFVQLYTYQIC 247
Query: 401 RSVCFLHDL-GIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINP 459
R++ +LH + G+ H D+KP+N+L+ +T
Sbjct: 248 RALNYLHRVVGVCHRDIKPQNLLVNPQT-------------------------------H 276
Query: 460 EVKLIDFGSAVFYNEYHPPV--VSTRHYRAPEIVLG-LGWSFPCDIWSIACVLVELVTGE 516
++K+ DFGSA P + + +R+YRAPE++ G ++ D+WS CV+ EL+ G+
Sbjct: 277 QLKICDFGSAKMLVPGEPNISYICSRYYRAPELIFGATEYTNAIDMWSGGCVMAELLLGQ 336
Query: 517 SLYPIHENTEHMAMMQRI 534
L+P + + + +I
Sbjct: 337 PLFPGESGIDQLVEIIKI 354
>At1g12580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 522
Score = 70.9 bits (172), Expect = 6e-12
Identities = 65/237 (27%), Positives = 104/237 (43%), Gaps = 44/237 (18%)
Query: 286 KNRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRY-----RQAAKTELRVLQTI 340
K+R+ + LG G FG + C D L +A K I + DR ++ K E+ ++ +
Sbjct: 41 KDRYVLGEQLGWGQFGVIRVCSDKLTGERLACKSI-SKDRLVTQDDMKSIKLEIAIMAKL 99
Query: 341 KENDRSGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQLV 400
+G + L+ ++ K+ + LV +L F Y R+ + + K L+
Sbjct: 100 -----AGHPNVVNLKAVYEEKDSVHLVMELCAGGEL-FHKLEKYGRYSEVRARVLFKHLM 153
Query: 401 RSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPE 460
+ V F HD GI+H DLKPENIL+ + S P
Sbjct: 154 QVVKFCHDSGIVHRDLKPENILM---ATMSSSSP-------------------------- 184
Query: 461 VKLIDFGSAVFY--NEYHPPVVSTRHYRAPEIVLGLGWSFPCDIWSIACVLVELVTG 515
+KL DFG A + E V + Y APE++ G G++ D+WS +L L++G
Sbjct: 185 IKLADFGLATYIKPGEKLSGTVGSPFYIAPEVLAG-GYNQAADVWSAGVILYILLSG 240
>ECU11g0960 [D] KOG0600 Cdc2-related protein kinase
Length = 329
Score = 70.5 bits (171), Expect = 8e-12
Identities = 59/250 (23%), Positives = 109/250 (43%), Gaps = 42/250 (16%)
Query: 272 EEGHYVYQENDIFAKNRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAK 331
EEG + K ++ ++++G+GTFG+V+ + A ++ V + ++
Sbjct: 5 EEGEILAHRRFTATKMEYEKIRIIGEGTFGQVILARKGR-----ARYALKKVSKEKEGLS 59
Query: 332 -TELRVLQTIKENDRSGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGS 390
T +R +Q ++ + L+ + I +V + + F+ +N + S
Sbjct: 60 VTTIREVQVLRAMGHPSIVR--LIEVVVEPGGDIYMVFPYFPYDLNRFIRSN---KMTCS 114
Query: 391 HVQAIGKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASG 450
++ I Q+ + VC++H GI+H DLK NIL+ +Q L I D R +G
Sbjct: 115 EIKHIFYQIAQGVCYIHSKGIMHRDLKSANILL------DQKLNASIADFGMARYTTKTG 168
Query: 451 GKRKILINPEVKLIDFGSAVFYNEYHPPVVSTRHYRAPEIVLG-LGWSFPCDIWSIACVL 509
+ P + T YRAPEI+LG +++ DIWS+ C+L
Sbjct: 169 A------------------------YTPGMVTLWYRAPEILLGSSSYTYAVDIWSLGCIL 204
Query: 510 VELVTGESLY 519
E+ G ++
Sbjct: 205 TEMYLGHMIF 214
>CE18009 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 384
Score = 70.5 bits (171), Expect = 8e-12
Identities = 61/254 (24%), Positives = 109/254 (42%), Gaps = 51/254 (20%)
Query: 286 KNRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKENDR 345
+ RF +++ +G+GT+G V K +++ A+K+IR T LR + IK+
Sbjct: 42 QGRFCSLRRIGEGTYGVVFKAIHVRDNVKCALKMIRTDRDEEGIPSTCLREISCIKDLQH 101
Query: 346 SG---QYQCLLLREFFDYKN----------HICLVTDLYGRSVYDF--MTNNGYARFPGS 390
+ + F +Y N + +V + R + + M + P +
Sbjct: 102 DNIVTLFDIIYASHFLNYNNIFFEKFSSNSKLYMVFEFIDRDLKNLLEMLEPTNSVLPPN 161
Query: 391 HVQAIGKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASG 450
+V++ QL+ ++ + H I+H DLKP+NIL+ D
Sbjct: 162 YVKSFMWQLLSALSYCHLRRIVHRDLKPQNILVSD------------------------- 196
Query: 451 GKRKILINPEVKLIDFGSA---VFYNEYHPPVVSTRHYRAPEIVLG-LGWSFPCDIWSIA 506
+ +K+ DFG A F + + V T YR PEI+LG +S D+WS+
Sbjct: 197 -------SGVIKIADFGLARNFSFPSRNYTHEVVTLWYRPPEILLGSQRYSTSLDMWSLG 249
Query: 507 CVLVELVTGESLYP 520
C+ E+ + + L+P
Sbjct: 250 CIFSEIASNKPLFP 263
>At1g73670 [T] KOG0660 Mitogen-activated protein kinase
Length = 576
Score = 70.5 bits (171), Expect = 8e-12
Identities = 65/242 (26%), Positives = 111/242 (45%), Gaps = 40/242 (16%)
Query: 287 NRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAV-DRYRQAAKT--ELRVLQTIKEN 343
NR+Q +++G+G++G V D VA+K I V D A + E+++L+ +
Sbjct: 88 NRYQIQEVVGKGSYGVVGSAIDTHTGERVAIKKINDVFDHISDATRILREIKLLRLLLHP 147
Query: 344 DRSGQYQCLL---LREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQLV 400
D +L REF D + +V +L ++ + N H Q QL+
Sbjct: 148 DVVEIKHIMLPPSRREFRD----VYVVFELMESDLHQVIKAND--DLTPEHHQFFLYQLL 201
Query: 401 RSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPE 460
R + ++H + H DLKP+NIL + C + K+ G ++ N
Sbjct: 202 RGLKYVHAANVFHRDLKPKNIL-ANADC---------------KLKICDFGLARVSFN-- 243
Query: 461 VKLIDFGSAVFYNEYHPPVVSTRHYRAPEIVLGL--GWSFPCDIWSIACVLVELVTGESL 518
D +A+F+ +Y V+TR YRAPE+ ++ DIWS+ C+ E++ G+ L
Sbjct: 244 ----DAPTAIFWTDY----VATRWYRAPELCGSFFSKYTPAIDIWSVGCIFAEMLLGKPL 295
Query: 519 YP 520
+P
Sbjct: 296 FP 297
>Hs5453860 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 496
Score = 70.1 bits (170), Expect = 1e-11
Identities = 64/245 (26%), Positives = 106/245 (43%), Gaps = 43/245 (17%)
Query: 295 LGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKENDRSGQYQCLLL 354
LG+GT+ V K K L D VA+K IR ++ A T +R + +K+ + + L
Sbjct: 171 LGEGTYATVYKGKSKLTDNLVALKEIR-LEHEEGAPCTAIREVSLLKDLKHAN---IVTL 226
Query: 355 REFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQLVRSVCFLHDLGIIHT 414
+ + + LV + + + ++ + G +V+ QL+R + + H ++H
Sbjct: 227 HDIIHTEKSLTLVFEYLDKDLKQYLDDCGNI-INMHNVKLFLFQLLRGLAYCHRQKVLHR 285
Query: 415 DLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKLIDFGSA----V 470
DLKP+N+LI + E+KL DFG A +
Sbjct: 286 DLKPQNLLINE--------------------------------RGELKLADFGLARAKSI 313
Query: 471 FYNEYHPPVVSTRHYRAPEIVLG-LGWSFPCDIWSIACVLVELVTGESLYPIHENTEHMA 529
Y VV T YR P+I+LG +S D+W + C+ E+ TG L+P E +
Sbjct: 314 PTKTYSNEVV-TLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRPLFPGSTVEEQLH 372
Query: 530 MMQRI 534
+ RI
Sbjct: 373 FIFRI 377
>Hs15011928 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 448
Score = 70.1 bits (170), Expect = 1e-11
Identities = 64/245 (26%), Positives = 106/245 (43%), Gaps = 43/245 (17%)
Query: 295 LGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKENDRSGQYQCLLL 354
LG+GT+ V K K L D VA+K IR ++ A T +R + +K+ + + L
Sbjct: 123 LGEGTYATVYKGKSKLTDNLVALKEIR-LEHEEGAPCTAIREVSLLKDLKHAN---IVTL 178
Query: 355 REFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQLVRSVCFLHDLGIIHT 414
+ + + LV + + + ++ + G +V+ QL+R + + H ++H
Sbjct: 179 HDIIHTEKSLTLVFEYLDKDLKQYLDDCGNI-INMHNVKLFLFQLLRGLAYCHRQKVLHR 237
Query: 415 DLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKLIDFGSA----V 470
DLKP+N+LI + E+KL DFG A +
Sbjct: 238 DLKPQNLLINE--------------------------------RGELKLADFGLARAKSI 265
Query: 471 FYNEYHPPVVSTRHYRAPEIVLG-LGWSFPCDIWSIACVLVELVTGESLYPIHENTEHMA 529
Y VV T YR P+I+LG +S D+W + C+ E+ TG L+P E +
Sbjct: 266 PTKTYSNEVV-TLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRPLFPGSTVEEQLH 324
Query: 530 MMQRI 534
+ RI
Sbjct: 325 FIFRI 329
>ECU11g1500 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 300
Score = 70.1 bits (170), Expect = 1e-11
Identities = 70/240 (29%), Positives = 112/240 (46%), Gaps = 41/240 (17%)
Query: 282 DIFAKNRFQAMQLLGQGTFGKVVKCK-DYLNDITVAVKIIRAVDRYRQAAKTELRVLQTI 340
DI A RF+ ++ L +G G V + + VA K + + RYR+ A+ E+ +L +I
Sbjct: 12 DIHAVERFRFIRRLSRGAHGTVYLLETEAPTREKVACKSM--LKRYRRYAEKEVEMLSSI 69
Query: 341 KENDRSGQYQCLLLREFFDYKNHICLVTDL--YG--RSVYDFMTNNGYARFPGSHVQAIG 396
+ + L +FF K+ + ++ + YG + +++ NGY R G V ++
Sbjct: 70 SHR------RVVRLLDFFPTKSGLSIILEYLNYGSLHEMIEYLMENGY-RVAGDLVWSVL 122
Query: 397 KQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKIL 456
Q + +LH IIH D+KP NIL+ + T V+ K ++L
Sbjct: 123 AQAADGLRYLHSKQIIHRDVKPSNILM-NRTLVQ---------------------KEELL 160
Query: 457 INPEVKLIDFGSA--VFYNEYHPPVVSTRHYRAPEIVLGLGWSFPCDIWSIACVLVELVT 514
E KL DF A + E +V T Y APE+V G +S DIWS+ + EL+T
Sbjct: 161 ---EFKLCDFSLAKNLCGKESVCGIVGTPSYMAPEVVSGERYSTSVDIWSLGISIYELLT 217
>Hs4502745 [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 464
Score = 69.7 bits (169), Expect = 1e-11
Identities = 69/257 (26%), Positives = 109/257 (41%), Gaps = 41/257 (15%)
Query: 295 LGQGTFGKVVKCK--DYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKENDRSGQYQCL 352
+G+GT+G V K K D +D A+K I A + E+ +L+ +K + +
Sbjct: 27 VGRGTYGHVYKAKRKDGKDDKDYALKQIEGTGISMSACR-EIALLRELKHPNVISLQKVF 85
Query: 353 LLRE------FFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQLVRSVCFL 406
L FDY H + R+ N + P V+++ Q++ + +L
Sbjct: 86 LSHADRKVWLLFDYAEHDLWHIIKFHRAS---KANKKPVQLPRGMVKSLLYQILDGIHYL 142
Query: 407 HDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKLIDF 466
H ++H DLKP NIL+ E R K+A G ++ +P L D
Sbjct: 143 HANWVLHRDLKPANILVMGE------------GPERGRVKIADMGFARLFNSPLKPLADL 190
Query: 467 GSAVFYNEYHPPVVSTRHYRAPEIVLGL-GWSFPCDIWSIACVLVELVTGESLYPIHE-- 523
PVV T YRAPE++LG ++ DIW+I C+ EL+T E ++ +
Sbjct: 191 ----------DPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQED 240
Query: 524 ----NTEHMAMMQRINN 536
N H + RI N
Sbjct: 241 IKTSNPYHHDQLDRIFN 257
>Hs20479818 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 514
Score = 69.7 bits (169), Expect = 1e-11
Identities = 63/255 (24%), Positives = 112/255 (43%), Gaps = 39/255 (15%)
Query: 270 TDEEGHYVYQENDIFAKNRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQA 329
T+ + ++ EN + + ++LG+G+FG V++ D + A+K + A
Sbjct: 97 TEGKVPHIRIENGAAIEEIYTFGRILGKGSFGIVIEATDKETETKWAIKKVNKEKAGSSA 156
Query: 330 AKT---ELRVLQTIKENDRSGQYQCLLLREFFDYKNHICLVTDLY-GRSVYDFMTNNGYA 385
K E+ +L+++K + L + F+ + LV +L + + + G+
Sbjct: 157 VKLLEREVNILKSVKHE------HIIHLEQVFETPKKMYLVMELCEDGELKEILDRKGH- 209
Query: 386 RFPGSHVQAIGKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERR 445
F + + I + L ++ +LH+ I+H DLK ENI++ +ID E
Sbjct: 210 -FSENETRWIIQSLASAIAYLHNNDIVHRDLKLENIMV----------KSSLIDDNNE-- 256
Query: 446 KLASGGKRKILINPEVKLIDFGSAVFYNEYHPPVVS----TRHYRAPEIVLGLGWSFPCD 501
IN +K+ DFG AV ++ T Y APE++ +S CD
Sbjct: 257 -----------INLNIKVTDFGLAVKKQSRSEAMLQATCGTPIYMAPEVISAHDYSQQCD 305
Query: 502 IWSIACVLVELVTGE 516
IWSI V+ L+ GE
Sbjct: 306 IWSIGVVMYMLLRGE 320
>Hs20149547 [T] KOG0603 Ribosomal protein S6 kinase
Length = 735
Score = 69.7 bits (169), Expect = 1e-11
Identities = 67/271 (24%), Positives = 125/271 (45%), Gaps = 51/271 (18%)
Query: 277 VYQENDIFAKNRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELRV 336
++ +N +F+ + + +G G++ + +C ++ AVK+I D+ ++ E+ +
Sbjct: 407 LHGKNLVFSDG-YVVKETIGVGSYSECKRCVHKATNMEYAVKVI---DKSKRDPSEEIEI 462
Query: 337 LQTIKENDRSGQYQCLL-LREFFDYKNHICLVTDLY--GRSVYDFMTNNGYARFPGSHV- 392
L R GQ+ ++ L++ +D H+ LVT+L G + + ++ S V
Sbjct: 463 LL------RYGQHPNIITLKDVYDDGKHVYLVTELMRGGELLDKILRQKFFSEREASFVL 516
Query: 393 QAIGKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGK 452
IGK +V +LH G++H DLKP NIL DE SG
Sbjct: 517 HTIGK----TVEYLHSQGVVHRDLKPSNILYVDE----------------------SG-- 548
Query: 453 RKILINPE-VKLIDFGSAVFYNEYHPPVVS---TRHYRAPEIVLGLGWSFPCDIWSIACV 508
NPE +++ DFG A + +++ T ++ APE++ G+ CDIWS+ +
Sbjct: 549 -----NPECLRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDEGCDIWSLGIL 603
Query: 509 LVELVTGESLYPIHENTEHMAMMQRINNEKF 539
L ++ G + + + ++ RI + KF
Sbjct: 604 LYTMLAGYTPFANGPSDTPEEILTRIGSGKF 634
Score = 63.2 bits (152), Expect = 1e-09
Identities = 65/266 (24%), Positives = 105/266 (39%), Gaps = 48/266 (18%)
Query: 275 HYVYQENDIFAKNRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTEL 334
H+V ++ + F+ +++LGQG+FGKV + K+ R + A K
Sbjct: 48 HHVKAGSEKADPSHFELLKVLGQGSFGKVFLVR----------KVTRPDSGHLYAMKVLK 97
Query: 335 RVLQTIKENDRSGQYQCLL--LREFFDYKNHICLVTDLYGRSVYDFMTNNGY-------A 385
+ +++ R+ + +L + F K H T+ + DF+
Sbjct: 98 KATLKVRDRVRTKMERDILADVNHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEV 157
Query: 386 RFPGSHVQAIGKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERR 445
F V+ +L + LH LGII+ DLKPENIL+ +E +
Sbjct: 158 MFTEEDVKFYLAELALGLDHLHSLGIIYRDLKPENILLDEEGHI---------------- 201
Query: 446 KLASGGKRKILINPEVKLIDFGSAVFYNEYHPPVVSTRHYRAPEIVLGLGWSFPCDIWSI 505
KL G K I+ E K F T Y APE+V G S D WS
Sbjct: 202 KLTDFGLSKEAIDHEKKAYSF-------------CGTVEYMAPEVVNRQGHSHSADWWSY 248
Query: 506 ACVLVELVTGESLYPIHENTEHMAMM 531
++ E++TG + + E M ++
Sbjct: 249 GVLMFEMLTGSLPFQGKDRKETMTLI 274
>Hs4502557 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 473
Score = 69.3 bits (168), Expect = 2e-11
Identities = 64/252 (25%), Positives = 105/252 (41%), Gaps = 45/252 (17%)
Query: 289 FQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIR-AVDRYRQAAKTELRVLQTIKENDRSG 347
F+ LG+G V +CK A+K+++ VD+ + +TE+ VL + +
Sbjct: 46 FEVESELGRGATSIVYRCKQKGTQKPYALKVLKKTVDK--KIVRTEIGVLLRLSHPN--- 100
Query: 348 QYQCLLLREFFDYKNHICLVTDLY-GRSVYDFMTNNGYARFPGSHVQAIGKQLVRSVCFL 406
+ L+E F+ I LV +L G ++D + GY + KQ++ +V +L
Sbjct: 101 ---IIKLKEIFETPTEISLVLELVTGGELFDRIVEKGY--YSERDAADAVKQILEAVAYL 155
Query: 407 HDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKLIDF 466
H+ GI+H DLKPEN+L + +K+ DF
Sbjct: 156 HENGIVHRDLKPENLLYATPA-----------------------------PDAPLKIADF 186
Query: 467 G--SAVFYNEYHPPVVSTRHYRAPEIVLGLGWSFPCDIWSIACVLVELVTGESLYPIHEN 524
G V + V T Y APEI+ G + D+WS+ + L+ G P ++
Sbjct: 187 GLSKIVEHQVLMKTVCGTPGYCAPEILRGCAYGPEVDMWSVGIITYILLCG--FEPFYDE 244
Query: 525 TEHMAMMQRINN 536
M +RI N
Sbjct: 245 RGDQFMFRRILN 256
>ECU08g1920 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 296
Score = 69.3 bits (168), Expect = 2e-11
Identities = 71/275 (25%), Positives = 115/275 (41%), Gaps = 55/275 (20%)
Query: 289 FQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKENDRSGQ 348
FQ ++ +G+GT+G V K ++ + VA+K IR + T +R + +K S
Sbjct: 5 FQKLEKIGEGTYGVVYKARERNTNRVVALKKIRLENENEGIPATTIREILLLKNLKHSTI 64
Query: 349 YQCLLLREFFDYKNHICLV---TDLYGRSVYDFMTNNGYARFPGSHVQAIGKQLVRSVCF 405
+ L + N + LV +L R D M++ G G V+ + +QL+ ++ +
Sbjct: 65 VE---LSDVIYNNNKMYLVFEYVELDLRRYLDRMSDEGRLVEEG-FVRKMSQQLLTAMEY 120
Query: 406 LHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKLID 465
H I H DLKP+NIL+ P E +KL D
Sbjct: 121 CHSRNIFHRDLKPQNILVD---------PKE-----------------------NIKLAD 148
Query: 466 FG----SAVFYNEYHPPVVSTRHYRAPEIVLGLG-WSFPCDIWSIACVLVELVTGESLYP 520
FG + + Y VV T YR PE++LG + D+WS AC++ E+V +P
Sbjct: 149 FGLGRAAGIPLRTYTTEVV-TLWYRPPELLLGCKYYDASVDVWSAACIMAEVVLMRPFFP 207
Query: 521 IHENTEHMAMMQRI----------NNEKFPKKMVE 545
+ + + ++ N E FP VE
Sbjct: 208 GDSEIDQLFRIFKVLGTPNNSRWSNVENFPNYKVE 242
>CE20458 [T] KOG1290 Serine/threonine protein kinase
Length = 782
Score = 69.3 bits (168), Expect = 2e-11
Identities = 48/185 (25%), Positives = 96/185 (50%), Gaps = 19/185 (10%)
Query: 257 SHQDKLRSMDRFKTDEE-----------GHYVYQENDIFAKNRFQAMQLLGQGTFGKVVK 305
S QD + ++ +D+E G++ D+F R+ ++ LG G F V
Sbjct: 92 SFQDPMDPGEQLGSDDEEQEDPRDYKRGGYHPVNIGDVF-NARYHVIRKLGWGHFSTVWL 150
Query: 306 CKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKENDRS--GQYQCLLLREFFDYKN- 362
D + VA+KI+++ + Y +AA E+++L +++ D + G ++ + L + F
Sbjct: 151 AWDTQDKRFVAMKIVKSAEHYTEAALDEIKLLLSVRSADPNDIGCHKVVQLLDEFTVTGI 210
Query: 363 ---HICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQLVRSVCFLHD-LGIIHTDLKP 418
H+ +V ++ G ++ + + Y V+ I +Q++ ++ ++H+ GIIHTD+KP
Sbjct: 211 NGQHVAMVFEVLGCNLLKLIIRSNYRGLHLEQVRKICRQVLEALGYMHEKCGIIHTDIKP 270
Query: 419 ENILI 423
EN+LI
Sbjct: 271 ENVLI 275
Score = 64.3 bits (155), Expect = 6e-10
Identities = 27/68 (39%), Positives = 43/68 (62%)
Query: 460 EVKLIDFGSAVFYNEYHPPVVSTRHYRAPEIVLGLGWSFPCDIWSIACVLVELVTGESLY 519
+VK+ D G+A + N ++ + TR YRA E+++G G+ P DIWS AC+ EL TG+ L+
Sbjct: 522 DVKIADLGNACWVNHHYTDDIQTRQYRALEVLIGSGYGPPADIWSTACMAFELATGDYLF 581
Query: 520 PIHENTEH 527
H+ +
Sbjct: 582 EPHQGDNY 589
>CE20457 [T] KOG1290 Serine/threonine protein kinase
Length = 698
Score = 69.3 bits (168), Expect = 2e-11
Identities = 48/185 (25%), Positives = 96/185 (50%), Gaps = 19/185 (10%)
Query: 257 SHQDKLRSMDRFKTDEE-----------GHYVYQENDIFAKNRFQAMQLLGQGTFGKVVK 305
S QD + ++ +D+E G++ D+F R+ ++ LG G F V
Sbjct: 92 SFQDPMDPGEQLGSDDEEQEDPRDYKRGGYHPVNIGDVF-NARYHVIRKLGWGHFSTVWL 150
Query: 306 CKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKENDRS--GQYQCLLLREFFDYKN- 362
D + VA+KI+++ + Y +AA E+++L +++ D + G ++ + L + F
Sbjct: 151 AWDTQDKRFVAMKIVKSAEHYTEAALDEIKLLLSVRSADPNDIGCHKVVQLLDEFTVTGI 210
Query: 363 ---HICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQLVRSVCFLHD-LGIIHTDLKP 418
H+ +V ++ G ++ + + Y V+ I +Q++ ++ ++H+ GIIHTD+KP
Sbjct: 211 NGQHVAMVFEVLGCNLLKLIIRSNYRGLHLEQVRKICRQVLEALGYMHEKCGIIHTDIKP 270
Query: 419 ENILI 423
EN+LI
Sbjct: 271 ENVLI 275
Score = 64.3 bits (155), Expect = 6e-10
Identities = 27/68 (39%), Positives = 43/68 (62%)
Query: 460 EVKLIDFGSAVFYNEYHPPVVSTRHYRAPEIVLGLGWSFPCDIWSIACVLVELVTGESLY 519
+VK+ D G+A + N ++ + TR YRA E+++G G+ P DIWS AC+ EL TG+ L+
Sbjct: 455 DVKIADLGNACWVNHHYTDDIQTRQYRALEVLIGSGYGPPADIWSTACMAFELATGDYLF 514
Query: 520 PIHENTEH 527
H+ +
Sbjct: 515 EPHQGDNY 522
>CE02949 [T] KOG1290 Serine/threonine protein kinase
Length = 1093
Score = 69.3 bits (168), Expect = 2e-11
Identities = 48/185 (25%), Positives = 96/185 (50%), Gaps = 19/185 (10%)
Query: 257 SHQDKLRSMDRFKTDEE-----------GHYVYQENDIFAKNRFQAMQLLGQGTFGKVVK 305
S QD + ++ +D+E G++ D+F R+ ++ LG G F V
Sbjct: 477 SFQDPMDPGEQLGSDDEEQEDPRDYKRGGYHPVNIGDVF-NARYHVIRKLGWGHFSTVWL 535
Query: 306 CKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKENDRS--GQYQCLLLREFFDYKN- 362
D + VA+KI+++ + Y +AA E+++L +++ D + G ++ + L + F
Sbjct: 536 AWDTQDKRFVAMKIVKSAEHYTEAALDEIKLLLSVRSADPNDIGCHKVVQLLDEFTVTGI 595
Query: 363 ---HICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQLVRSVCFLHD-LGIIHTDLKP 418
H+ +V ++ G ++ + + Y V+ I +Q++ ++ ++H+ GIIHTD+KP
Sbjct: 596 NGQHVAMVFEVLGCNLLKLIIRSNYRGLHLEQVRKICRQVLEALGYMHEKCGIIHTDIKP 655
Query: 419 ENILI 423
EN+LI
Sbjct: 656 ENVLI 660
Score = 64.3 bits (155), Expect = 6e-10
Identities = 27/68 (39%), Positives = 43/68 (62%)
Query: 460 EVKLIDFGSAVFYNEYHPPVVSTRHYRAPEIVLGLGWSFPCDIWSIACVLVELVTGESLY 519
+VK+ D G+A + N ++ + TR YRA E+++G G+ P DIWS AC+ EL TG+ L+
Sbjct: 840 DVKIADLGNACWVNHHYTDDIQTRQYRALEVLIGSGYGPPADIWSTACMAFELATGDYLF 899
Query: 520 PIHENTEH 527
H+ +
Sbjct: 900 EPHQGDNY 907
>At2g38490 [T] KOG0583 Serine/threonine protein kinase
Length = 431
Score = 69.3 bits (168), Expect = 2e-11
Identities = 67/239 (28%), Positives = 104/239 (43%), Gaps = 52/239 (21%)
Query: 288 RFQAMQLLGQGTFGKVVKCKDYLND-ITVAVKII---RAVDRYRQAAKTELRVLQTIKEN 343
++ +LLG G F KV + +D N +VA+K++ R D K E+ V++ ++
Sbjct: 27 KYDLGKLLGSGAFAKVYQAEDLQNGGESVAIKVVQKKRLKDGLTAHVKREISVMRRLRHP 86
Query: 344 DRSGQYQCLLLREFFDYKNHICLVTDLY-GRSVYDFMTNNGYARFPGSHVQAIGKQLVRS 402
+LL E K I V +L G ++ +T+N RF S + +QL+ +
Sbjct: 87 ------HIVLLSEVLATKTKIYFVMELAKGGELFSRVTSN---RFTESLSRKYFRQLISA 137
Query: 403 VCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVK 462
V + H G+ H DLKPEN+L+ DE N ++K
Sbjct: 138 VRYCHARGVFHRDLKPENLLL-DE-------------------------------NRDLK 165
Query: 463 LIDFGSAVFYNEYHP-----PVVSTRHYRAPEIVLGLGW-SFPCDIWSIACVLVELVTG 515
+ DFG + + HP + T Y APE++L G+ DIWS VL L G
Sbjct: 166 VSDFGLSAMKEQIHPDGMLHTLCGTPAYVAPELLLKKGYDGSKADIWSCGVVLFLLNAG 224
>YNR031c [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and related
serine/threonine protein kinases
Length = 1579
Score = 68.9 bits (167), Expect = 2e-11
Identities = 73/280 (26%), Positives = 122/280 (43%), Gaps = 45/280 (16%)
Query: 288 RFQAMQLLGQGTFGKVVKCKDYLNDITVAVKII-----RAVDRYRQAAKTELRVLQTIKE 342
R+Q +G GTFG+V D N +AVK I +++ + K E+ VL+ +
Sbjct: 1265 RWQKRNFIGGGTFGRVYSAVDLDNGEILAVKEINIQDSKSMQKIFPLIKEEMSVLEILNH 1324
Query: 343 NDRSGQYQCLLLRE----FFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQ 398
+ Y + R+ F +Y L L + D M Y Q
Sbjct: 1325 PNIVSYYGVEVHRDKVNIFMEYCEGGSLAALLEHGRIEDEMVTQVYTL-----------Q 1373
Query: 399 LVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILIN 458
L+ + +LH+ GI+H D+KPENIL+ + + ++ +D +K+A+ G R +N
Sbjct: 1374 LLEGLAYLHESGIVHRDVKPENILL------DFNGVIKYVD-FGAAKKIANNGTRLASMN 1426
Query: 459 ---------PEVKLIDFGSAVFYNEYH-PPVVSTRHYRAPEIVLG---LGWSFPCDIWSI 505
+V + AV NE ++ T Y APE + G G D+WS+
Sbjct: 1427 KIENADGEHEDVTHVSDSKAVKNNENALLDMMGTPMYMAPESITGSTTKGKLGADDVWSL 1486
Query: 506 ACVLVELVTGESLYPIHENTEHMAMMQRI---NNEKFPKK 542
CV++E++TG + +N A+M + + +FP K
Sbjct: 1487 GCVVLEMITGRRPWANLDN--EWAIMYHVAAGHTPQFPTK 1524
>SPBC8D2.19 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 559
Score = 68.9 bits (167), Expect = 2e-11
Identities = 71/268 (26%), Positives = 119/268 (43%), Gaps = 36/268 (13%)
Query: 270 TDEEGHYVYQENDIFAKNRFQAMQLLGQGTFGKVV----KCKDYLNDITVAVKIIRAVDR 325
++E + V + ++R+ Q LG G+FG V K K+ L + TVAVK ++ +
Sbjct: 2 SNESIYSVLDLTQVIFEDRYLVKQKLGDGSFGTVYLAQRKEKNGLYE-TVAVKKLK--NS 58
Query: 326 YRQAAKTELRVLQTIKENDRSGQYQCL--LLREFFDYKNHICLVTDLYGRSVYDFMTNNG 383
+ K EL L+ + ++ CL LL F D +I LV + +++
Sbjct: 59 SKPKPKHELLKLRESLALRKISKHPCLIDLLETFMDPYRNIFLVMEFMDCNLFQLFKRRQ 118
Query: 384 YARFPGSHVQAIGKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTE 443
F I Q++ + +H G +H D+KPENIL V++ P I +
Sbjct: 119 GRLFTKETAFNILLQIISGIEHIHKHGFMHRDIKPENIL------VKRISPKPISSRYS- 171
Query: 444 RRKLASGGKRKILINPEVKLIDFGSAVFYNEYHP--PVVSTRHYRAPEIVLGLG-WSFPC 500
+KL DFG A P VSTR YRAPE++L G ++
Sbjct: 172 -----------------IKLGDFGLARPSVSSDPLTEYVSTRWYRAPELLLRSGSYNHSV 214
Query: 501 DIWSIACVLVELVTGESLYPIHENTEHM 528
D+++ C++ E+ + + L+P T+ +
Sbjct: 215 DLYAFGCIVFEIYSLKPLFPGRNETDQL 242
>Hs7706549 [D] KOG0600 Cdc2-related protein kinase
Length = 1490
Score = 68.9 bits (167), Expect = 2e-11
Identities = 62/266 (23%), Positives = 115/266 (42%), Gaps = 45/266 (16%)
Query: 287 NRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQA----AKTELRVLQTIKE 342
++F + ++G+GT+G+V K +D VA+K +R +D ++ A E+++L+ +
Sbjct: 725 DKFDIIGIIGEGTYGQVYKARDKDTGELVALKKVR-LDNEKEGFPITAIREIKILRQLIH 783
Query: 343 NDRSGQYQCLL-LREFFDYKNHICLVTDLYGRSVYDFM--TNNGYARFPGSHVQAIGKQL 399
+ + ++ D+K ++ +D M +G F H+++ KQL
Sbjct: 784 RSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFMKQL 843
Query: 400 VRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINP 459
+ + + H +H D+K NIL+ + +
Sbjct: 844 MEGLEYCHKKNFLHRDIKCSNILLNN--------------------------------SG 871
Query: 460 EVKLIDFGSAVFYN--EYHPPV--VSTRHYRAPEIVLGLGWSFPC-DIWSIACVLVELVT 514
++KL DFG A YN E P V T YR PE++LG P D+WS C+L EL T
Sbjct: 872 QIKLADFGLARLYNSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFT 931
Query: 515 GESLYPIHENTEHMAMMQRINNEKFP 540
+ ++ + + ++ R+ P
Sbjct: 932 KKPIFQANLELAQLELISRLCGSPCP 957
>Hs4557511 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 454
Score = 68.9 bits (167), Expect = 2e-11
Identities = 77/346 (22%), Positives = 135/346 (38%), Gaps = 71/346 (20%)
Query: 278 YQENDIFAKNRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKII---------RAVDRYRQ 328
+++ D+ ++ ++ + LG G F V KC+ A K I R V R +
Sbjct: 4 FRQEDV--EDHYEMGEELGSGQFAIVRKCRQKGTGKEYAAKFIKKRRLSSSRRGVSR--E 59
Query: 329 AAKTELRVLQTIKENDRSGQYQCLLLREFFDYKNHICLVTDLY-GRSVYDFMTNNGYARF 387
+ E+ +L+ I+ + + L + F+ K + L+ +L G ++DF+
Sbjct: 60 EIEREVNILREIRHPN------IITLHDIFENKTDVVLILELVSGGELFDFLAEK--ESL 111
Query: 388 PGSHVQAIGKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKL 447
KQ++ V +LH I H DLKPENI++ D
Sbjct: 112 TEDEATQFLKQILDGVHYLHSKRIAHFDLKPENIMLLD---------------------- 149
Query: 448 ASGGKRKILINPEVKLIDFGSA--VFYNEYHPPVVSTRHYRAPEIVLGLGWSFPCDIWSI 505
K + NP +KLIDFG A + + T + APEIV D+WSI
Sbjct: 150 ------KNVPNPRIKLIDFGIAHKIEAGNEFKNIFGTPEFVAPEIVNYEPLGLEADMWSI 203
Query: 506 ACVLVELVTGESLYPIHENTEHMAMMQRI----------NNEKFPKKMVEKMFFKVENKY 555
+ L++G S + E + + + N + K + ++ K +
Sbjct: 204 GVITYILLSGASPFLGETKQETLTNISAVNYDFDEEYFSNTSELAKDFIRRLLVKDPKRR 263
Query: 556 GSIPTDLQTSVVKYFDRQTGELRWPLRNSKGQVITKEKSWKRILAT 601
+I L+ S +K R RN +G+ ++ +R+ T
Sbjct: 264 MTIAQSLEHSWIKAIRR---------RNVRGEDSGRKPERRRLKTT 300
>Hs14670383 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 370
Score = 68.9 bits (167), Expect = 2e-11
Identities = 82/348 (23%), Positives = 144/348 (40%), Gaps = 65/348 (18%)
Query: 295 LGQGTFGKVVKCKDYLNDITVAVKII-----RAVDR--YRQAAKTELRVLQTIKENDRSG 347
LG G F V KC++ + A K I RA R R+ + E+ +L+ + ++
Sbjct: 29 LGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGVSREEIEREVSILRQVLHHN--- 85
Query: 348 QYQCLLLREFFDYKNHICLVTDLY-GRSVYDFMTNNGYARFPGSHVQAIGKQLVRSVCFL 406
+ L + ++ + + L+ +L G ++DF+ + KQ++ V +L
Sbjct: 86 ---VITLHDVYENRTDVVLILELVSGGELFDFLAQK--ESLSEEEATSFIKQILDGVNYL 140
Query: 407 HDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKLIDF 466
H I H DLKPENI++ D +++P+ P +KLIDF
Sbjct: 141 HTKKIAHFDLKPENIMLLD-----KNIPI-----------------------PHIKLIDF 172
Query: 467 GSA--VFYNEYHPPVVSTRHYRAPEIVLGLGWSFPCDIWSIACVLVELVTGESLYPIHEN 524
G A + + T + APEIV D+WSI + L++G S +
Sbjct: 173 GLAHEIEDGVEFKNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGDTK 232
Query: 525 TEHMAMMQRIN---NEKF-------PKKMVEKMFFKVENKYGSIPTDLQTSVVKYFDRQT 574
E +A + ++ +E+F K + K+ K K +I L+ + D Q
Sbjct: 233 QETLANITAVSYDFDEEFFSQTSELAKDFIRKLLVKETRKRLTIQEALRHPWITPVDNQQ 292
Query: 575 GELRWP----LRNSKGQVITKEKSWK---RILATCDRLDVFISKKLQM 615
+R L N + Q + + WK I++ C+ L + KK+ +
Sbjct: 293 AMVRRESVVNLENFRKQYV--RRRWKLSFSIVSLCNHLTRSLMKKVHL 338
>CE18608 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 342
Score = 68.9 bits (167), Expect = 2e-11
Identities = 62/248 (25%), Positives = 103/248 (41%), Gaps = 41/248 (16%)
Query: 289 FQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKENDRSGQ 348
FQ Q LG+G +G V + + + A+K I + ++ LR + +K R
Sbjct: 38 FQIHQALGKGAYGNVYRVRSLHDGKDYALKQIMISSKNEGIPQSVLREITVMKHLARKAH 97
Query: 349 YQCLLLREFF---DYKNHICLVTDLYGRSVYDFMT--NNGYARFPGSHVQAIGKQLVRSV 403
+ L+ F D I + + R +D T N P + + Q+VR++
Sbjct: 98 PNIISLKSVFHQLDPVRAILKINMIMERCDWDLHTFLRNIPRGVPEQQAKHVTAQIVRAL 157
Query: 404 CFLHDLGIIHTDLKPENILI-CDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVK 462
FLH IIH DLKP+NIL+ D+T VK
Sbjct: 158 DFLHTHSIIHRDLKPQNILLNRDQT---------------------------------VK 184
Query: 463 LIDFGSAVFYNE--YHPPVVSTRHYRAPEIVLGLGWSFPCDIWSIACVLVELVTGESLYP 520
L DFG + Y+ +V T YR+PE++L ++ D+W++ C++ E+ + L+
Sbjct: 185 LADFGLSKEYSNTTAFTTLVVTLWYRSPEVLLQSYYNSTVDMWALGCIVSEIYCRQPLFV 244
Query: 521 IHENTEHM 528
E +
Sbjct: 245 GQNEAEQL 252
>At3g07980 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 1367
Score = 68.9 bits (167), Expect = 2e-11
Identities = 62/258 (24%), Positives = 108/258 (41%), Gaps = 42/258 (16%)
Query: 287 NRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKENDRS 346
N++ +G+G +G+V D N VA+K + + ++ T ++ + +K +
Sbjct: 18 NKYMLGDEIGKGAYGRVYIGLDLENGDFVAIKQVSLENIGQEDLNTIMQEIDLLKNLNHK 77
Query: 347 GQYQCLLLREFFDYKNHICLVTD-LYGRSVYDFMTNNGYARFPGSHVQAIGKQLVRSVCF 405
+ L K H+ ++ + + S+ + + N + FP S V Q++ + +
Sbjct: 78 NIVKYL---GSLKTKTHLHIILEYVENGSLANIIKPNKFGPFPESLVTVYIAQVLEGLVY 134
Query: 406 LHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKLID 465
LH+ G+IH D+K NIL E VKL D
Sbjct: 135 LHEQGVIHRDIKGANILTTKEGL--------------------------------VKLAD 162
Query: 466 FGSAVFYNEYH---PPVVSTRHYRAPEIVLGLGWSFPCDIWSIACVLVELVTGESLYPIH 522
FG A NE VV T ++ APE++ G DIWS+ C ++EL+T P +
Sbjct: 163 FGVATKLNEADFNTHSVVGTPYWMAPEVIELSGVCAASDIWSVGCTIIELLT---CVPPY 219
Query: 523 ENTEHMAMMQRINNEKFP 540
+ + M + RI + P
Sbjct: 220 YDLQPMPALYRIVQDDTP 237
>At1g48490 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1244
Score = 68.9 bits (167), Expect = 2e-11
Identities = 57/233 (24%), Positives = 103/233 (43%), Gaps = 19/233 (8%)
Query: 289 FQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKENDRSGQ 348
F+ M+ + +G FG V+ + A+K++R D R+ A + + I N R+
Sbjct: 828 FEVMKSISRGAFGHVILARKNTTGDLFAIKVLRKADMIRKNAVESILAERDILINARNP- 886
Query: 349 YQCLLLREFFDY---KNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQLVRSVCF 405
++R F+ + +N ++ L G Y + G + V ++V ++ +
Sbjct: 887 ---FVVRFFYSFTCSENLYLVMEYLNGGDFYSMLRKIGCLDEANARVYIA--EVVLALEY 941
Query: 406 LHDLGIIHTDLKPENILICDETCVEQS---LPMEIIDSLTERRKLASGGKRKILINPEVK 462
LH G++H DLKP+N+LI + V+ + L + + T+ +L+ + K
Sbjct: 942 LHSEGVVHRDLKPDNLLIAHDGHVKLTDFGLSKVGLINNTDDLSGPVSSATSLLVEEKPK 1001
Query: 463 LIDFGSAVFYNEYHPPVVSTRHYRAPEIVLGLGWSFPCDIWSIACVLVELVTG 515
L ++ V T Y APEI+LG G D WS+ +L E + G
Sbjct: 1002 LPTL-------DHKRSAVGTPDYLAPEILLGTGHGATADWWSVGIILYEFLVG 1047
>Hs22050308_2 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 291
Score = 68.9 bits (167), Expect = 2e-11
Identities = 56/247 (22%), Positives = 109/247 (43%), Gaps = 34/247 (13%)
Query: 293 QLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKENDRSGQYQ-- 350
Q +G G F + +D +AVK + V R + + V++ ++E R +
Sbjct: 24 QQIGLGAFSSCYQAQDVGTGTLMAVKQVTYV---RNTSSEQEEVVEALREEIRMMSHLNH 80
Query: 351 ---CLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQLVRSVCFLH 407
+L + N+ + + G SV ++ Y F S V +QL+R + +LH
Sbjct: 81 PNIIRMLGATCEKSNYNLFIEWMAGGSVAHLLSK--YGAFKESVVINYTEQLLRGLSYLH 138
Query: 408 DLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKLIDFG 467
+ IIH D+K N+LI DS +R ++A G +L G
Sbjct: 139 ENQIIHRDVKGANLLI---------------DSTGQRLRIADFGAA-------ARLASKG 176
Query: 468 SAVFYNEYHPPVVSTRHYRAPEIVLGLGWSFPCDIWSIACVLVELVTGESLYPIHENTEH 527
+ E+ ++ T + APE++ G + CD+WS+ C ++E+ + + +++ H
Sbjct: 177 TGA--GEFQGQLLGTIAFMAPEVLRGQQYGRSCDVWSVGCAIIEMACAKPPWNAEKHSNH 234
Query: 528 MAMMQRI 534
+A++ ++
Sbjct: 235 LALIFKV 241
>Hs4503095 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 391
Score = 68.6 bits (166), Expect = 3e-11
Identities = 62/293 (21%), Positives = 134/293 (45%), Gaps = 50/293 (17%)
Query: 271 DEEGHYVYQENDIFAKNRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAA 330
D E H V N ++ +Q ++ LG+G + +V + + N+ V VKI++ V + +
Sbjct: 25 DYESHVVEWGN----QDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKK--I 78
Query: 331 KTELRVLQTIKENDRSGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGS 390
K E+++L+ ++ G + L + K+ + L V + Y
Sbjct: 79 KREIKILENLR-----GGPNIITLADIV--KDPVSRTPALVFEHVNNTDFKQLYQTLTDY 131
Query: 391 HVQAIGKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASG 450
++ ++++++ + H +GI+H D+KP N++I E RKL
Sbjct: 132 DIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHE-----------------HRKL--- 171
Query: 451 GKRKILINPEVKLIDFGSAVFYN---EYHPPVVSTRHYRAPEIVLGLG-WSFPCDIWSIA 506
+LID+G A FY+ EY+ V S R+++ PE+++ + + D+WS+
Sbjct: 172 -----------RLIDWGLAEFYHPGQEYNVRVAS-RYFKGPELLVDYQMYDYSLDMWSLG 219
Query: 507 CVLVELV-TGESLYPIHENTEHMAMMQRINNEKFPKKMVEKMFFKVENKYGSI 558
C+L ++ E + H+N + + + ++ + ++K +++ ++ I
Sbjct: 220 CMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDI 272
>Hs20551615 [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 358
Score = 68.6 bits (166), Expect = 3e-11
Identities = 64/234 (27%), Positives = 103/234 (43%), Gaps = 35/234 (14%)
Query: 295 LGQGTFGKVVKC--KDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKENDRSGQYQCL 352
+G+GT+G V K KD ++ A+K I A + E+ +L+ +K + +
Sbjct: 27 VGRGTYGHVYKARRKDGKDEKEYALKQIEGTGISMSACR-EIALLRELKHPNVIALQKVF 85
Query: 353 LLRE------FFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQLVRSVCFL 406
L FDY H + R+ N + P S V+++ Q++ + +L
Sbjct: 86 LSHSDRKVWLLFDYAEHDLWHIIKFHRAS---KANKKPMQLPRSMVKSLLYQILDGIHYL 142
Query: 407 HDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKLIDF 466
H ++H DLKP NIL+ E R K+A G ++ +P L D
Sbjct: 143 HANWVLHRDLKPANILVMGE------------GPERGRVKIADMGFARLFNSPLKPLADL 190
Query: 467 GSAVFYNEYHPPVVSTRHYRAPEIVLGL-GWSFPCDIWSIACVLVELVTGESLY 519
PVV T YRAPE++LG ++ DIW+I C+ EL+T E ++
Sbjct: 191 ----------DPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIF 234
>Hs20502986 [T] KOG0660 Mitogen-activated protein kinase
Length = 277
Score = 68.6 bits (166), Expect = 3e-11
Identities = 76/263 (28%), Positives = 116/263 (43%), Gaps = 68/263 (25%)
Query: 288 RFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKENDRSG 347
R+ + LGQG +G V K D VA+K I D +R KT+ + +T +E
Sbjct: 12 RYLLRRQLGQGAYGIVWKAVDRRTGEVVAIKKI--FDAFRD--KTDAQ--RTFRE----- 60
Query: 348 QYQCLLLREFFDYKNHICLVTDLYGRS------VYDFM-------------------TNN 382
LL+EF D+ N I L+ + + V++FM N
Sbjct: 61 ---ITLLQEFGDHPNIISLLDVIRAENDRDIYLVFEFMGCPPSPPPPTAVRTLSADTDLN 117
Query: 383 GYARFPGS----HVQAIGKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEII 438
R G HV++I QL+R+ FLH ++H D KP N+L+ D C + +
Sbjct: 118 AVIRKGGLLQDVHVRSIFYQLLRATRFLHSGHVVHRDQKPSNVLL-DANCTVKLCDFGLA 176
Query: 439 DSLTERRKLASGGKRKILINPEVKLIDFGSAVFYNEYHPPVVSTRHYRAPEIVLGL-GWS 497
SL + L G PE + + EY V+TR YRAPE++L ++
Sbjct: 177 RSLGD---LPEG--------PEDQAV--------TEY----VATRWYRAPEVLLSSHRYT 213
Query: 498 FPCDIWSIACVLVELVTGESLYP 520
D+WS+ C+L E++ G L+P
Sbjct: 214 LGVDMWSLGCILGEMLRGRPLFP 236
>At2g01450 [T] KOG0660 Mitogen-activated protein kinase
Length = 516
Score = 68.6 bits (166), Expect = 3e-11
Identities = 71/275 (25%), Positives = 120/275 (42%), Gaps = 52/275 (18%)
Query: 287 NRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAA---KTELRVLQTIKEN 343
+++Q +++G+G++G V + VA+K + V + A E+++L+ ++
Sbjct: 14 SQYQIQEVVGKGSYGVVASAECPHTGGKVAIKKMTNVFEHVSDAIRILREIKLLRLLRHP 73
Query: 344 DRSGQYQCLL---LREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQLV 400
D +L +EF D I +V +L ++ + N H Q QL+
Sbjct: 74 DIVEIKHIMLPPCRKEFKD----IYVVFELMESDLHHVLKVND--DLTPQHHQFFLYQLL 127
Query: 401 RSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPE 460
R + F+H + H DLKP+NIL ++I D R
Sbjct: 128 RGLKFMHSAHVFHRDLKPKNIL------ANADCKIKICDLGLAR---------------- 165
Query: 461 VKLIDFGSAVFYNEYHPPVVSTRHYRAPEIVLGL--GWSFPCDIWSIACVLVELVTGESL 518
V D SAVF+ +Y V+TR YRAPE+ ++ D+WS+ C+ E++TG+ L
Sbjct: 166 VSFTDSPSAVFWTDY----VATRWYRAPELCGSFYSNYTPAIDMWSVGCIFAEMLTGKPL 221
Query: 519 YP----IHE--------NTEHMAMMQRINNEKFPK 541
+P +H+ T + RI NEK K
Sbjct: 222 FPGKNVVHQLELVTDLLGTPSPITLSRIRNEKARK 256
>CE26793_1 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 795
Score = 68.6 bits (166), Expect = 3e-11
Identities = 62/235 (26%), Positives = 104/235 (43%), Gaps = 42/235 (17%)
Query: 286 KNRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTEL-RVLQTIKEND 344
K+RF+ + LG GT+GKV D+ D VAVK+I+ + +K +L R+ + I+
Sbjct: 72 KHRFEITKKLGSGTYGKVSLAYDHKFDREVAVKLIK---KSAIESKADLVRIRREIRIMS 128
Query: 345 RSGQYQCLLLREFFDYKNHICLVTDL-YGRSVYDFMTNNGYARFPGSHVQAIGKQLVRSV 403
+ + E F+ K+ I LV + G +YD+++ G P + + I +Q+ +V
Sbjct: 129 ALNHPNIIQIYEVFENKDKIILVMEYSSGGELYDYVSRCG--SLPEAEARRIFRQITSAV 186
Query: 404 CFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKL 463
+ H + H DLK ENIL+ N K+
Sbjct: 187 LYCHKHRVAHRDLKLENILLDQ--------------------------------NNNAKI 214
Query: 464 IDFGSAVFYNEYH--PPVVSTRHYRAPEIVLGLGWSFP-CDIWSIACVLVELVTG 515
DFG + ++ + + + Y +PEI+ G + P D WS+ +L LV G
Sbjct: 215 ADFGLSNYFADKNLLTTFCGSPLYASPEIINGTPYKGPEVDCWSLGILLYTLVYG 269
>YAL017w [T] KOG1152 Signal transduction serine/threonine kinase with PAS/PAC
sensor domain
Length = 1356
Score = 68.2 bits (165), Expect = 4e-11
Identities = 70/257 (27%), Positives = 110/257 (42%), Gaps = 59/257 (22%)
Query: 289 FQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAV---------DRYRQAAKTELRVLQT 339
F ++Q +G+G +GKV C N V +K+I DR +E++++ T
Sbjct: 1096 FVSLQKMGEGAYGKVNLCIHKKNRYIVVIKMIFKERILVDTWVRDRKLGTIPSEIQIMAT 1155
Query: 340 IKENDRSGQYQCLLLREFFDYKNHICLVTDLYGRS-------VYDFMTNNGYARFPGSHV 392
+ + L L +FF+ ++ + T ++G + + +F TN
Sbjct: 1156 LNKKPHEN---ILRLLDFFEDDDYYYIETPVHGETGCIDLFDLIEFKTN-----MTEFEA 1207
Query: 393 QAIGKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGK 452
+ I KQ+V + LHD GI+H D+K EN+ I+DS
Sbjct: 1208 KLIFKQVVAGIKHLHDQGIVHRDIKDENV---------------IVDS------------ 1240
Query: 453 RKILINPEVKLIDFGSAVFYNEYHPPV-VSTRHYRAPEIVLGLGW-SFPCDIWSIACVLV 510
VK+IDFGSA + V V T Y APE++ G + P DIW+I +L
Sbjct: 1241 -----KGFVKIIDFGSAAYVKSGPFDVFVGTIDYAAPEVLGGNPYEGQPQDIWAIGILLY 1295
Query: 511 ELVTGES-LYPIHENTE 526
+V E+ Y I E E
Sbjct: 1296 TVVFKENPFYNIDEILE 1312
>SPACUNK12.02c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 335
Score = 68.2 bits (165), Expect = 4e-11
Identities = 58/235 (24%), Positives = 109/235 (45%), Gaps = 42/235 (17%)
Query: 288 RFQAMQLLGQGTFGKVVKCKDYLNDITVAVKII--RAVDRYRQAAKTELRVLQTIKENDR 345
+++ ++LG GT+ V + + A KI+ + +++ + K E+ +L+ +
Sbjct: 30 KYRVGRVLGGGTYATVREAVHIETNKMYAAKIMNKKMMEKKQDFVKNEIAILKRVSYEHP 89
Query: 346 SGQYQCLLLREFFDYKNHICLVTDLY-GRSVYDFMTNNGYARFPGSHVQAIGKQLVRSVC 404
+ L L +FF+ N++ L+T+L G ++D + G F + A+ + +V
Sbjct: 90 N----ILHLVDFFETVNNLYLITELATGGELFDRICAKG--SFYEADAAALMRTTTSAVK 143
Query: 405 FLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKLI 464
+LHD GI+H DLKPEN+L R N ++ +
Sbjct: 144 YLHDNGIVHRDLKPENLLY-----------------------------RSKDPNSDLLIA 174
Query: 465 DFGSAVFY--NEYHPPVVS--TRHYRAPEIVLGLGWSFPCDIWSIACVLVELVTG 515
DFG + FY ++Y+ + + T Y APE+ G+ P D+W+I + L++G
Sbjct: 175 DFGLSHFYEDSQYYMLMTACGTPEYMAPEVFRRTGYGKPVDMWAIGVITYFLLSG 229
>Hs7662170 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 661
Score = 68.2 bits (165), Expect = 4e-11
Identities = 58/255 (22%), Positives = 119/255 (45%), Gaps = 37/255 (14%)
Query: 286 KNRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKENDR 345
K+R++ + LG+GT+GKV + + + VA+K IR D+ + + + + + I+
Sbjct: 52 KHRYELQETLGKGTYGKVKRATERFSGRVVAIKSIRK-DKIKD-EQDMVHIRREIEIMSS 109
Query: 346 SGQYQCLLLREFFDYKNHICLVTDLYGR-SVYDFMTNNGYARFPGSHVQAIGKQLVRSVC 404
+ + E F+ K+ I ++ + + +YD+++ R + +Q+V +V
Sbjct: 110 LNHPHIISIYEVFENKDKIVIIMEYASKGELYDYISER--RRLSERETRHFFRQIVSAVH 167
Query: 405 FLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKLI 464
+ H G++H DLK ENIL+ D+ C K+A G + +
Sbjct: 168 YCHKNGVVHRDLKLENILL-DDNC---------------NIKIADFGLSNLYQKDKFLQT 211
Query: 465 DFGSAVFYNEYHPPVVSTRHYRAPEIVLGLGWSFPCDIWSIACVLVELVTGESLYPIHEN 524
GS ++ + P +V+ R YR PE+ D W++ +L LV G + +
Sbjct: 212 FCGSPLYAS---PEIVNGRPYRGPEV----------DSWALGVLLYTLVYGTMPF---DG 255
Query: 525 TEHMAMMQRINNEKF 539
+H ++++I++ ++
Sbjct: 256 FDHKNLIRQISSGEY 270
>At1g73690 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 398
Score = 68.2 bits (165), Expect = 4e-11
Identities = 57/231 (24%), Positives = 98/231 (41%), Gaps = 40/231 (17%)
Query: 287 NRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKENDRS 346
+R+ ++LGQGT+G V K D N TVA+K IR T LR ++ +KE
Sbjct: 9 DRYLKREVLGQGTYGVVFKATDTKNGETVAIKKIRLGKEKEGVNVTALREIKLLKELKHP 68
Query: 347 GQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQLVRSVCFL 406
+ L + F +K ++ +V + + + + PG V++ + +++ + +
Sbjct: 69 ---HIIELIDAFPHKENLHIVFEFMETDLEAVIRDRNLYLSPGD-VKSYLQMILKGLEYC 124
Query: 407 HDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKLIDF 466
H ++H D+KP N+LI N ++KL DF
Sbjct: 125 HGKWVLHRDMKPNNLLIGP--------------------------------NGQLKLADF 152
Query: 467 GSAVFY---NEYHPPVVSTRHYRAPEIVLGL-GWSFPCDIWSIACVLVELV 513
G A + V R YRAPE++ G + D+W+ C+ EL+
Sbjct: 153 GLARIFGSPGRKFTHQVFARWYRAPELLFGAKQYDGAVDVWAAGCIFAELL 203
>SPBC119.08 [T] KOG0660 Mitogen-activated protein kinase
Length = 422
Score = 67.8 bits (164), Expect = 5e-11
Identities = 71/263 (26%), Positives = 116/263 (43%), Gaps = 56/263 (21%)
Query: 275 HYVYQ--ENDIFAKNRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKT 332
H VY+ +++ + F+ ++ LGQG +G V ++ + AV I + + + ++ T
Sbjct: 5 HRVYRVFNQEMYVEPNFKVVKELGQGAYGIVCAARNVASKDQEAVAIKKITNVFSKSILT 64
Query: 333 ELRVLQTIKENDRSGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHV 392
+ R L+ IK LL F +++N C+ DL + Y+F Y + +
Sbjct: 65 K-RALREIK-----------LLIHFRNHRNITCIY-DLDIINPYNFNEVYIYEELMEADL 111
Query: 393 QAIGK---------------QLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEI 437
AI K Q++ + ++H +IH DLKP N+L V ++I
Sbjct: 112 NAIIKSGQPLTDAHFQSFIYQILCGLKYIHSANVIHRDLKPGNLL------VNADCELKI 165
Query: 438 IDSLTERRKLASGGKRKILINPEVKLIDFGSAVFYNEYHPPVVSTRHYRAPEIVLGL-GW 496
D G R NPE + F EY V+TR YRAPEI+L +
Sbjct: 166 CD---------FGLARGCSENPE------ENPGFMTEY----VATRWYRAPEIMLSFSSY 206
Query: 497 SFPCDIWSIACVLVELVTGESLY 519
D+WS+ C+L EL+ G L+
Sbjct: 207 HKGIDVWSVGCILAELLGGTPLF 229
>SPAC3C7.06c [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 650
Score = 67.8 bits (164), Expect = 5e-11
Identities = 61/250 (24%), Positives = 110/250 (43%), Gaps = 33/250 (13%)
Query: 289 FQAMQLLGQGTFGKV--VKCKDYLNDITVAVKIIRAVDRYRQAAKT-ELRVLQTIKENDR 345
+ ++ +G GTFG V K ++ + + + + A + E+ L + EN+
Sbjct: 36 YNVVRKVGDGTFGSVYLATTKTPSKEVVAIKSMKKKLAKVSDATRLREVHSLLRLSENEN 95
Query: 346 SGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQLVRSVCF 405
L + +F + +V + ++Y ++ VQ I +Q+ + +
Sbjct: 96 IVNIFDLYIDQF----RCLHIVMEFLDCNLYQLISTRKNDPLTLEQVQDIMRQIFKGLNH 151
Query: 406 LHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKLID 465
+H G H D+KPENILI + DS + K+A G + +
Sbjct: 152 IHTNGFFHRDMKPENILISSNS-----------DSSSFNVKIADFGLAR----------E 190
Query: 466 FGSAVFYNEYHPPVVSTRHYRAPEIVL-GLGWSFPCDIWSIACVLVELVTGESLYPIHEN 524
S Y EY VSTR YRAPE++L +SFP DI++ C+ E+ T + ++P +++
Sbjct: 191 INSRPPYTEY----VSTRWYRAPELLLRDSYYSFPVDIYAAGCMAFEIATLQPIFPGNDD 246
Query: 525 TEHMAMMQRI 534
+ + M I
Sbjct: 247 FDQLYKMCEI 256
>Hs4506735 [T] KOG0603 Ribosomal protein S6 kinase
Length = 772
Score = 67.8 bits (164), Expect = 5e-11
Identities = 61/225 (27%), Positives = 100/225 (44%), Gaps = 38/225 (16%)
Query: 295 LGQGTFGKVVKCKDYLNDITVAVKII-RAVDRYRQAAKTELRVLQTIKENDRSGQYQCLL 353
LGQG+F +C+ + AVKI+ R ++ Q LR+ Q+ +
Sbjct: 417 LGQGSFSVCRRCRQRQSGQEFAVKILSRRLEANTQREVAALRLCQS--------HPNVVN 468
Query: 354 LREFFDYKNHICLVTDLY-GRSVYDFMTNNGYARFPGSHVQAIGKQLVRSVCFLHD-LGI 411
L E + H LV +L G + + + + F S I + LV +V F+H+ G+
Sbjct: 469 LHEVHHDQLHTYLVLELLRGGELLEHIRKKRH--FSESEASQILRSLVSAVSFMHEEAGV 526
Query: 412 IHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKLIDFGSAVF 471
+H DLKPENIL D+T P++IID R + P+ + + F
Sbjct: 527 VHRDLKPENILYADDT---PGAPVKIIDFGFAR------------LRPQSPGVPMQTPCF 571
Query: 472 YNEYHPPVVSTRHYRAPEIVLGLGWSFPCDIWSIACVLVELVTGE 516
T Y APE++ G+ CD+WS+ +L +++G+
Sbjct: 572 ----------TLQYAAPELLAQQGYDESCDLWSLGVILYMMLSGQ 606
>Hs16160923 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 472
Score = 67.8 bits (164), Expect = 5e-11
Identities = 63/245 (25%), Positives = 105/245 (42%), Gaps = 43/245 (17%)
Query: 295 LGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKENDRSGQYQCLLL 354
LG+GT+ V K + L + VA+K IR ++ A T +R + +K + + L
Sbjct: 148 LGEGTYATVFKGRSKLTENLVALKEIR-LEHEEGAPCTAIREVSLLKNLKHAN---IVTL 203
Query: 355 REFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQLVRSVCFLHDLGIIHT 414
+ + LV + + ++ + G +V+ QL+R + + H I+H
Sbjct: 204 HDLIHTDRSLTLVFEYLDSDLKQYLDHCGNL-MSMHNVKIFMFQLLRGLAYCHHRKILHR 262
Query: 415 DLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKLIDFGSA----V 470
DLKP+N+LI + E+KL DFG A V
Sbjct: 263 DLKPQNLLINE--------------------------------RGELKLADFGLARAKSV 290
Query: 471 FYNEYHPPVVSTRHYRAPEIVLG-LGWSFPCDIWSIACVLVELVTGESLYPIHENTEHMA 529
Y VV T YR P+++LG +S P D+W + C+ E+ TG L+P E +
Sbjct: 291 PTKTYSNEVV-TLWYRPPDVLLGSTEYSTPIDMWGVGCIHYEMATGRPLFPGSTVKEELH 349
Query: 530 MMQRI 534
++ R+
Sbjct: 350 LIFRL 354
>At1g54960 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 585
Score = 67.8 bits (164), Expect = 5e-11
Identities = 64/255 (25%), Positives = 111/255 (43%), Gaps = 35/255 (13%)
Query: 288 RFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKE----N 343
R++ QL+G+G FG V + + +AVK + KT+ + + +E
Sbjct: 67 RWRKGQLIGRGAFGTVYMGMNLDSGELLAVKQVLITSNCASKEKTQAHIQELEEEVKLLK 126
Query: 344 DRSGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQLVRSV 403
+ S L + + L+ + G S+ + G FP S V+ QL+ +
Sbjct: 127 NLSHPNIVRYLGTVREDETLNILLEFVPGGSISSLLEKFG--AFPESVVRTYTNQLLLGL 184
Query: 404 CFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKL 463
+LH+ I+H D+K NIL+ ++ C+ KLA G K + +L
Sbjct: 185 EYLHNHAIMHRDIKGANILVDNQGCI----------------KLADFGASKQV----AEL 224
Query: 464 IDFGSAVFYNEYHPPVVSTRHYRAPEIVLGLGWSFPCDIWSIACVLVELVTGESLYPIHE 523
A + T ++ APE++L G SF DIWS+ C ++E+VTG++ P +
Sbjct: 225 ATISGA-------KSMKGTPYWMAPEVILQTGHSFSADIWSVGCTVIEMVTGKA--PWSQ 275
Query: 524 NTEHMAMMQRINNEK 538
+ +A + I K
Sbjct: 276 QYKEIAAIFHIGTTK 290
>7291043 [T] KOG0660 Mitogen-activated protein kinase
Length = 392
Score = 67.8 bits (164), Expect = 5e-11
Identities = 74/285 (25%), Positives = 123/285 (42%), Gaps = 55/285 (19%)
Query: 265 MDRFKTDEEGHYVYQENDIFAKNRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVD 324
M ++T QE D ++ F + +G+G +G V K D TVA+K + D
Sbjct: 1 MANYQTAHAQERRIQELDQTVESIFDVRKRMGKGAYGIVWKATDRRTKNTVALK--KVFD 58
Query: 325 RYRQAAKTELRVLQTIKENDRSGQY-QCLLLREFFDYKNHICLVTDLYGRS-------VY 376
+R E D Y + + LR F + N + LV D++ S V+
Sbjct: 59 AFRD-------------ETDAQRTYREVIFLRAFRCHPNIVRLV-DIFKASNNLDFYLVF 104
Query: 377 DFMTNNGYARFPGS------HVQAIGKQLVRSVCFLHDLGIIHTDLKPENILICDETCVE 430
+FM ++ + H + + QL+ ++ F+H +IH DLKP NILI D C
Sbjct: 105 EFMESDLHNVIKRGNVLKDVHKRFVMYQLINAIKFIHSGNVIHRDLKPSNILI-DSKC-- 161
Query: 431 QSLPMEIIDSLTERRKLASGGKRKILINPEVKLIDFGSAVFYNEYHPPVVSTRHYRAPEI 490
R K+A G + L + + D +Y V+TR YRAPEI
Sbjct: 162 -------------RLKVADFGLARTLSSRRI-YDDLEQDGMLTDY----VATRWYRAPEI 203
Query: 491 -VLGLGWSFPCDIWSIACVLVELVTGESLYPIHENTEHMAMMQRI 534
V ++ D+W + C+L E++ + P+ + T + +++I
Sbjct: 204 LVASRNYTKGIDMWGLGCILGEMIRQK---PLFQGTSTVNQIEKI 245
>YDL079c [G] KOG0658 Glycogen synthase kinase-3
Length = 501
Score = 67.4 bits (163), Expect = 7e-11
Identities = 60/237 (25%), Positives = 107/237 (44%), Gaps = 41/237 (17%)
Query: 289 FQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKENDRSGQ 348
+ +++G G+FG VV + VA+K + RY+ EL ++ + + G
Sbjct: 164 YPTTEVVGHGSFGVVVTTVIIETNQKVAIKKVLQDRRYK---NRELETMKMLCHPNTVG- 219
Query: 349 YQCLLLREFFDYKNHICLVTDLYGRSVYDFMTN--NGYARFPGSHVQAIGKQLVRSVCFL 406
Q + + + ++ LV D +S+Y + + N + P ++ QL +++ +L
Sbjct: 220 LQYYFYEKDEEDEVYLNLVLDYMPQSLYQRLRHFVNLKMQMPRVEIKFYAYQLFKALNYL 279
Query: 407 HDL-GIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKLID 465
H++ I H D+KP+N+L+ T K+ D
Sbjct: 280 HNVPRICHRDIKPQNLLVDPTTF-------------------------------SFKICD 308
Query: 466 FGSAVFYNEYHPPV--VSTRHYRAPEIVLG-LGWSFPCDIWSIACVLVELVTGESLY 519
FGSA P V + +R+YRAPE++ G +S D+WS ACV+ EL+ G+ L+
Sbjct: 309 FGSAKCLKPDQPNVSYICSRYYRAPELMFGATNYSNQVDVWSSACVIAELLLGKPLF 365
>Hs9966875 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 357
Score = 67.4 bits (163), Expect = 7e-11
Identities = 66/256 (25%), Positives = 110/256 (42%), Gaps = 44/256 (17%)
Query: 265 MDRFKTDEEGHYVYQENDIFAKNRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKII--RA 322
M R + + Q DI K F+ + LG G F +VV ++ AVK I +A
Sbjct: 1 MARENGESSSSWKKQAEDI--KKIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKA 58
Query: 323 VDRYRQAAKTELRVLQTIKENDRSGQYQCLLLREFFDYKNHICLVTDLY-GRSVYDFMTN 381
+ + + E+ VL+ IK + + L + ++ NH+ LV L G ++D +
Sbjct: 59 LKGKESSIENEIAVLRKIKHEN------IVALEDIYESPNHLYLVMQLVSGGELFDRIVE 112
Query: 382 NGYARFPGSHVQAIGKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSL 441
G+ + + +Q++ +V +LH +GI+H DLKPEN+L + E+S
Sbjct: 113 KGF--YTEKDASTLIRQVLDAVYYLHRMGIVHRDLKPENLLYYSQD--EES--------- 159
Query: 442 TERRKLASGGKRKILINPEVKLIDFGSAVF--YNEYHPPVVSTRHYRAPEIVLGLGWSFP 499
KI+I+ DFG + + T Y APE++ +S
Sbjct: 160 ------------KIMIS------DFGLSKMEGKGDVMSTACGTPGYVAPEVLAQKPYSKA 201
Query: 500 CDIWSIACVLVELVTG 515
D WSI + L+ G
Sbjct: 202 VDCWSIGVIAYILLCG 217
>CE24516 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 856
Score = 67.4 bits (163), Expect = 7e-11
Identities = 55/239 (23%), Positives = 109/239 (45%), Gaps = 41/239 (17%)
Query: 289 FQAMQLLGQGTFGKVVKCKDYLN--DITVAVKII--RAVDRYRQAAKTELRVLQ---TIK 341
+ LLG G F V + + Y++ D+ VA+K I + + + + E+++L+ ++K
Sbjct: 9 YSKRDLLGHGAFAIVYRGR-YVDRTDVPVAIKAIAKKNISKSKNLLTKEIKILKELSSLK 67
Query: 342 ENDRSGQYQCLLLREFFDYKNHICLVTDLY-GRSVYDFMTNNGYARFPGSHVQAIGKQLV 400
+ G +C + H+ LV + G + D++ +Q Q+
Sbjct: 68 HENLVGLLKCT------ETPTHVYLVMEFCNGGDLADYLQQK--TTLNEDTIQHFVVQIA 119
Query: 401 RSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPE 460
++ ++ GI+H DLKP+NIL+C+ + + +I+
Sbjct: 120 HALEAINKKGIVHRDLKPQNILLCNNSRTQNPHFTDIV---------------------- 157
Query: 461 VKLIDFGSAVFYNE--YHPPVVSTRHYRAPEIVLGLGWSFPCDIWSIACVLVELVTGES 517
+KL DFG A F N+ + + Y APE+++ + + D+WSI +L + +TG++
Sbjct: 158 IKLADFGFARFLNDGVMAATLCGSPMYMAPEVIMSMQYDAKADLWSIGTILFQCLTGKA 216
>YOL016c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 447
Score = 66.6 bits (161), Expect = 1e-10
Identities = 65/268 (24%), Positives = 122/268 (45%), Gaps = 44/268 (16%)
Query: 276 YVYQENDIFAKNRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELR 335
YV + N IF + LG G+FG V + + + VA+KI+ + + Q +L+
Sbjct: 41 YVNRTNYIFGRT-------LGAGSFGVVRQARKLSTNEDVAIKIL--LKKALQGNNVQLQ 91
Query: 336 VL-QTIKENDRSGQYQCLLLREFFDYKNHICLVTDLY-GRSVYDFMTNNGYARFPGSHVQ 393
+L + + + + +++F+ K+ +VT L G ++D + + G +F
Sbjct: 92 MLYEELSILQKLSHPNIVSFKDWFESKDKFYIVTQLATGGELFDRILSRG--KFTEVDAV 149
Query: 394 AIGKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIID-SLTERRKLASGGK 452
I Q++ +V ++H ++H DLKPEN+L D++ ++ P+ I D + ++ K G+
Sbjct: 150 EIIVQILGAVEYMHSKNVVHRDLKPENVLYVDKS---ENSPLVIADFGIAKQLK----GE 202
Query: 453 RKILINPEVKLIDFGSAVFYNEYHPPVVSTRHYRAPEIVLGLGWSFPCDIWSIACVLVEL 512
++ + Y APE++ G PCDIWSI + L
Sbjct: 203 EDLIYK--------------------AAGSLGYVAPEVLTQDGHGKPCDIWSIGVITYTL 242
Query: 513 VTGESLYPIHENTEHMAMMQRINNEKFP 540
+ G S + I E+ E M+ ++P
Sbjct: 243 LCGYSPF-IAESVE--GFMEECTASRYP 267
>Hs7706445 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 515
Score = 66.6 bits (161), Expect = 1e-10
Identities = 64/255 (25%), Positives = 110/255 (43%), Gaps = 47/255 (18%)
Query: 272 EEGHYVYQENDIFAKNRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAK 331
+ H+ Q+ DI + + +G G FG V D + VA+K + V + + K
Sbjct: 115 QHSHHPQQQLDI------EPDRPIGYGAFGVVWSVTDPRDGKRVALKKMPNVFQNLVSCK 168
Query: 332 TELRVLQTIK--ENDRSGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPG 389
R L+ + ++D +L DY I +VT+L ++ + +
Sbjct: 169 RVFRELKMLCFFKHDNVLSALDILQPPHIDYFEEIYVVTELMQSDLHKIIVSP--QPLSS 226
Query: 390 SHVQAIGKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLAS 449
HV+ Q++R + +LH GI+H D+KP N+L+ + CV
Sbjct: 227 DHVKVFLYQILRGLKYLHSAGILHRDIKPGNLLV-NSNCV-------------------- 265
Query: 450 GGKRKILINPEVKLIDFGSA----VFYNEYHPPVVSTRHYRAPEIVLG-LGWSFPCDIWS 504
+K+ DFG A + + + V T++YRAPEI++G +S DIWS
Sbjct: 266 -----------LKICDFGLARVEELDESRHMTQEVVTQYYRAPEILMGSRHYSNAIDIWS 314
Query: 505 IACVLVELVTGESLY 519
+ C+ EL+ L+
Sbjct: 315 VGCIFAELLGRRILF 329
>At3g10540 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 483
Score = 66.6 bits (161), Expect = 1e-10
Identities = 61/270 (22%), Positives = 126/270 (46%), Gaps = 31/270 (11%)
Query: 279 QENDIFAKNRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKII--RAVDRYRQAAKTELRV 336
QEN F + F+ ++ G G++ KVV+ K N A+KI+ + + + + A +L
Sbjct: 34 QEN--FTYHDFELGKIYGVGSYSKVVRAKKKDNGTVYALKIMDKKFITKENKTAYVKLER 91
Query: 337 LQTIKENDRSGQYQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIG 396
+ + + + G + L F D ++ + G ++D +T G R +
Sbjct: 92 I-VLDQLEHPGIVK--LFFTFQDTQSLYMALESCEGGELFDQITRKG--RLSEDEARFYS 146
Query: 397 KQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKIL 456
++V ++ ++H++G+IH D+KPEN+L+ +L K+A G K +
Sbjct: 147 AEVVDALEYIHNMGLIHRDIKPENLLL----------------TLDGHIKIADFGSVKPM 190
Query: 457 INPEVKLIDFGSAVFYNEYHPPVVSTRHYRAPEIVLGLGWSFPCDIWSIACVLVELVTGE 516
+ ++ ++ ++ ++ V T Y PE++ +F D+W++ C L ++++G
Sbjct: 191 QDSQITVLPNAAS---DDKACTFVGTAAYVPPEVLNSSPATFGNDLWALGCTLYQMLSGT 247
Query: 517 SLYPIHENTEHMAMMQRINNE-KFPKKMVE 545
S P + +E + + I + KFP E
Sbjct: 248 S--PFKDASEWLIFQRIIARDIKFPNHFSE 275
>SPCC1322.08 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 580
Score = 66.2 bits (160), Expect = 2e-10
Identities = 70/292 (23%), Positives = 119/292 (39%), Gaps = 23/292 (7%)
Query: 240 KSPSRFTKILKKSPLLGSHQDKLRSMDRFKTDEEGHYVYQENDIFAKNRFQAMQLLGQGT 299
++PS +++ K P DK K E H Q ++ +Q +G G
Sbjct: 75 ENPSEYSRSKCKQPTNEKEYDKAIEALVAKAIVEEHSGQQFPVYKGLEQYTLLQKMGDGA 134
Query: 300 FGKVVKCKDYLNDITVAVKIIRAVD--------RYRQAAKTELRVLQTIKENDRSGQYQC 351
F V K VA+K+++ R RQ ++ +L+ ++ R
Sbjct: 135 FSNVYKAIHNRTGEKVAIKVVQRAQPNTDPRDPRKRQGVESH-NILKEVQIMRRVKHPNI 193
Query: 352 LLLREFFDYKNHICLVTDLY--GRSVYDFMTNNGYARFPGSHVQAIGKQLVRSVCFLH-D 408
+ L EF + LV +L G + + ++ HV Q+ ++ +LH D
Sbjct: 194 IQLLEFIQTPEYYYLVLELADGGELFHQIVRLTYFSEDLSRHVIT---QVAHAIRYLHED 250
Query: 409 LGIIHTDLKPENILICDETCVEQSLPM----EIIDSLTERRKLASGGKRKILINPEVKLI 464
G++H D+KPEN+L V + + D + E + G I ++L
Sbjct: 251 CGVVHRDIKPENLLFDSIDFVPSRVRKYRAGDDPDKVDEGEFIPGVGAGTI---GRIRLA 307
Query: 465 DFG-SAVFYNEYHPPVVSTRHYRAPEIVLGLGWSFPCDIWSIACVLVELVTG 515
DFG S V ++ + T Y APEIV +S D+W++ CVL ++ G
Sbjct: 308 DFGLSKVVWDSHTQTPCGTMGYTAPEIVRDERYSKGVDMWALGCVLYTILCG 359
>Hs20986508 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 277
Score = 66.2 bits (160), Expect = 2e-10
Identities = 39/125 (31%), Positives = 60/125 (47%), Gaps = 34/125 (27%)
Query: 398 QLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILI 457
Q++ + LH GIIH DLKP NI++ + +
Sbjct: 27 QMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTL---------------------------- 58
Query: 458 NPEVKLIDFGSA--VFYNEYHPPVVSTRHYRAPEIVLGLGWSFPCDIWSIACVLVELVTG 515
K++DFG A + P V TR+YRAPE++LG+G+ DIWS+ C++ E+V
Sbjct: 59 ----KILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMVRH 114
Query: 516 ESLYP 520
+ L+P
Sbjct: 115 KILFP 119
>CE20167 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD and related
proteins
Length = 722
Score = 66.2 bits (160), Expect = 2e-10
Identities = 71/296 (23%), Positives = 124/296 (40%), Gaps = 47/296 (15%)
Query: 287 NRFQAM--QLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTE-LRVLQTIKEN 343
N +Q + + LG G FG V + VAVK+I ++ + E +R I +
Sbjct: 422 NLYQVLSDKTLGSGQFGTVYSAIQRHSGKEVAVKVISKERFSKKGSGAESMRAEVAILQQ 481
Query: 344 DRSGQYQCLLLREFF-DYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQLVRS 402
CL EF + K+ I +V + + + + + R + + Q++ +
Sbjct: 482 TCHPGIVCL---EFMCETKDKIFVVMEKMNGDMLEMILSQELGRLNSRATKFLLVQILCA 538
Query: 403 VCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVK 462
+ +LHD GI H DLKPEN+L+ D + S P+ K
Sbjct: 539 LKYLHDQGIAHCDLKPENVLLSD---------------------MGSN-------FPQTK 570
Query: 463 LIDFGSAVFY--NEYHPPVVSTRHYRAPEIVLGLGWSFPCDIWSIACVLVELVTGESLYP 520
+ DFG A F +++ VV T Y PE++ G++ D+WS+ ++ VT +P
Sbjct: 571 ICDFGYARFIPESQFRKTVVGTPAYLPPEVLQRKGYNKSLDMWSVGVII--YVTLSGTFP 628
Query: 521 IHENTEHMAMMQRINNEKF-----PKKMVEKMFFKVENKYGSIPTDLQTSVVKYFD 571
+E E + ++I N F P VE + + K + + + S+ + D
Sbjct: 629 FNEGEE---ISEQIQNASFMFPTEPWSEVEPLAVDLIQKLLKVEIEARMSIEQCLD 681
>At3g53030 [T] KOG1290 Serine/threonine protein kinase
Length = 523
Score = 66.2 bits (160), Expect = 2e-10
Identities = 39/121 (32%), Positives = 65/121 (53%), Gaps = 11/121 (9%)
Query: 425 DETCVEQSLPMEIIDSLTERR--KLASGGKRKILI---NPEVKLIDFGSAVFYNEYHPPV 479
+E C S +E+ S ++ K S R+ L+ + + KL+DFG+A + +
Sbjct: 259 EEDCPSTSDAIELDGSEKGKQGGKKGSRSSRRHLVASADLKCKLVDFGNACWTYKQFTSD 318
Query: 480 VSTRHYRAPEIVLGLGWSFPCDIWSIACVLVELVTGESLYPIH------ENTEHMAMMQR 533
+ TR YR PE++LG +S D+WS AC+ ELVTG+ L+ H + +H+A+M
Sbjct: 319 IQTRQYRCPEVILGSKYSTSADLWSFACICFELVTGDVLFDPHSGDNYDRDEDHLALMME 378
Query: 534 I 534
+
Sbjct: 379 L 379
Score = 63.5 bits (153), Expect = 1e-09
Identities = 43/155 (27%), Positives = 71/155 (45%), Gaps = 11/155 (7%)
Query: 274 GHYVYQENDIFAKNRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTE 333
G++ + D F R+ LG G F V D + + ++ Y +AA E
Sbjct: 27 GYHAVRIGDSFKTGRYVVQSKLGWGHFSTVWLSWDTQSSVQ------KSAQHYTEAAMDE 80
Query: 334 LRVLQTIKENDRSGQYQCLLLREFFDYKN----HICLVTDLYGRSVYDFMTNNGYARFPG 389
+ +LQ I E D + L + F + H+C+V + G ++ + + Y P
Sbjct: 81 ITILQQIAEGDTDDTKCVVKLLDHFKHSGPNGQHVCMVFEYLGDNLLTLIKYSDYRGLPI 140
Query: 390 SHVQAIGKQLVRSVCFLH-DLGIIHTDLKPENILI 423
V+ I ++ + +LH L IIHTDLKPEN+L+
Sbjct: 141 PMVKEICYHMLVGLDYLHKQLSIIHTDLKPENVLL 175
>7294866 [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 531
Score = 66.2 bits (160), Expect = 2e-10
Identities = 78/304 (25%), Positives = 129/304 (41%), Gaps = 57/304 (18%)
Query: 295 LGQGTFGKVVKCK--DYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKENDRSGQYQCL 352
+G+GT+G V K K + + A+K I A + E+ +L+ +K Q
Sbjct: 104 VGRGTYGHVYKAKWKETSDGKEYALKQIDGTGLSMSACR-EIALLRELKH-----QNVIT 157
Query: 353 LLREFFDYKNH-ICLVTDLYGRSVYDFMTNNGYAR-------FPGSHVQAIGKQLVRSVC 404
L+R F + + + L+ D ++ + + A+ P V+++ Q++ +
Sbjct: 158 LIRVFLSHNDRKVFLLIDYAEHDLWHIIKFHRAAKATKKQVVVPRGMVKSLLYQILDGIH 217
Query: 405 FLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKLI 464
+LH ++H DLKP NIL+ + + R K+A G ++ P L
Sbjct: 218 YLHSNWVLHRDLKPANILVMGD------------GNERGRVKIADMGFARLFNAPLKPLA 265
Query: 465 DFGSAVFYNEYHPPVVSTRHYRAPEIVLGL-GWSFPCDIWSIACVLVELVTGESLYPIHE 523
D PVV T YRAPE++LG ++ DIW+I C+ EL+T E ++ +
Sbjct: 266 DL----------DPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQ 315
Query: 524 ------NTEHMAMMQRINNEK-FP--------KKMVEKMFFKVENKYGSIPTDLQTSVVK 568
N H + RI N FP KKM E + K + T S+ K
Sbjct: 316 EDIKTSNPYHHDQLDRIFNVMGFPQDKDWEDIKKMPEHHTLTKDFKRSTYST---CSLAK 372
Query: 569 YFDR 572
Y +R
Sbjct: 373 YMER 376
>SPAC23H4.17c [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 352
Score = 65.9 bits (159), Expect = 2e-10
Identities = 96/417 (23%), Positives = 166/417 (39%), Gaps = 117/417 (28%)
Query: 286 KNRFQAMQLLGQGTFGKVVKC-KDYLNDITV-AVKIIRAVDRY----------RQAAKTE 333
K+ ++ + + GT+GKV K ND + A+K +A + Q+A E
Sbjct: 2 KDGYKIIGFISSGTYGKVYKAVSSNSNDKRLFAIKKFKAESKQVSSNAQQTGVSQSAIRE 61
Query: 334 LRVLQTIKENDRSGQYQCLL----LREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPG 389
+ + + I+ + Q LL + F+Y H L + F + + + P
Sbjct: 62 MMLCREIQHENIVSLVQVLLKDGTISMVFEYAEHDLL-------QIIHFHSRSRTRQIPP 114
Query: 390 SHVQAIGKQLVRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLAS 449
S +++I Q++ V +LH+ I+H DLKP NI+I + T + K+
Sbjct: 115 SILKSILWQIINGVAYLHENWIMHRDLKPANIMI----------------TATGKVKIGD 158
Query: 450 GGKRKILINPEVKLIDFGSAVFYNEYHPPVVSTRHYRAPEIVLGLGWSFPC-DIWSIACV 508
G +++ +P ++ F S+ VV T YRAPE++LG P D+W+I C+
Sbjct: 159 LGLGRLIRDP---ILPFYSS-------DRVVVTIWYRAPELLLGAHDYTPAIDVWAIGCI 208
Query: 509 LVELVTGESLYPIHENTEHMAMMQRINNEKFPKKMVEKMFFKVENKYGSIPTDLQTSVVK 568
E++ +L P+ + E KM +K K + +++
Sbjct: 209 YGEML---ALSPLFKGDE--------------IKMEDK-------KVVPFQSTQMLRIME 244
Query: 569 YFDRQTGELRWP-LRNSKGQVITKEKSWKRILATCDRLDVFISKKLQMDYGSWLEIHWDM 627
T E RWP L+N + + ++ Y + L W
Sbjct: 245 LLGTPTEE-RWPGLKNYP--------------------EYYQLSSFEVRYWNNLLPQWYQ 283
Query: 628 QLEDNWRLILSKNIDSRNIDKNVFMFWYYFVDLCRKMFEFDPTKRITAKEVIEHEWF 684
+ KN D + +D L KM ++DP RITAK+ +EH +F
Sbjct: 284 TV---------KNRDPQGLD------------LLMKMLQYDPKSRITAKQALEHVFF 319
>Hs16418343 [T] KOG0583 Serine/threonine protein kinase
Length = 268
Score = 65.9 bits (159), Expect = 2e-10
Identities = 65/235 (27%), Positives = 99/235 (41%), Gaps = 44/235 (18%)
Query: 282 DIFAKNRFQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTEL-RVLQTI 340
D N +Q + +G+GT+ KV + + VA+K+I + + + L R LQ +
Sbjct: 3 DFLLSNGYQLGKTIGEGTYSKVKEAFSKKHQRKVAIKVIDKMGGPEEFIQRFLPRELQIV 62
Query: 341 KENDRSGQYQCLLLREFFDYKNHICLVTDLY-GRSVYDFMTNNGYARFPGSHVQAIGKQL 399
+ D Q + E D K ICLV +L G V+D + N G P S +A+ +Q+
Sbjct: 63 RTLDHKNIIQVYEMLESADGK--ICLVMELAEGGDVFDCVLNGG--PLPESRAKALFRQM 118
Query: 400 VRSVCFLHDLGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINP 459
V ++ + H G+ H DLK EN L L
Sbjct: 119 VEAIRYCHGCGVAHRDLKCENAL---------------------------------LQGF 145
Query: 460 EVKLIDFGSAVFYNEYHPPVVST----RHYRAPEIVLGLGW-SFPCDIWSIACVL 509
+KL DFG A + H + T Y APE++ G+ S D+WS+ VL
Sbjct: 146 NLKLTDFGFAKVLPKSHRELSQTFCGSTAYAAPEVLQGIPHDSKKGDVWSMGVVL 200
>CE28918 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 406
Score = 65.9 bits (159), Expect = 2e-10
Identities = 60/244 (24%), Positives = 101/244 (40%), Gaps = 41/244 (16%)
Query: 293 QLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKENDRSGQYQCL 352
Q LG+G +G V + + + A+K I + ++ LR + +K R +
Sbjct: 106 QALGKGAYGNVYRVRSLHDGKDYALKQIMISSKNEGIPQSVLREITVMKHLARKAHPNII 165
Query: 353 LLREFF---DYKNHICLVTDLYGRSVYDFMT--NNGYARFPGSHVQAIGKQLVRSVCFLH 407
L+ F D I + + R +D T N P + + Q+VR++ FLH
Sbjct: 166 SLKSVFHQLDPVRAILKINMIMERCDWDLHTFLRNIPRGVPEQQAKHVTAQIVRALDFLH 225
Query: 408 DLGIIHTDLKPENILI-CDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKLIDF 466
IIH DLKP+NIL+ D+T VKL DF
Sbjct: 226 THSIIHRDLKPQNILLNRDQT---------------------------------VKLADF 252
Query: 467 GSAVFYNE--YHPPVVSTRHYRAPEIVLGLGWSFPCDIWSIACVLVELVTGESLYPIHEN 524
G + Y+ +V T YR+PE++L ++ D+W++ C++ E+ + L+
Sbjct: 253 GLSKEYSNTTAFTTLVVTLWYRSPEVLLQSYYNSTVDMWALGCIVSEIYCRQPLFVGQNE 312
Query: 525 TEHM 528
E +
Sbjct: 313 AEQL 316
>Hs21361433 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 970
Score = 65.5 bits (158), Expect = 3e-10
Identities = 53/230 (23%), Positives = 92/230 (39%), Gaps = 37/230 (16%)
Query: 289 FQAMQLLGQGTFGKVVKCKDYLNDITVAVKIIRAVDRYRQAAKTELRVLQTIKENDRSGQ 348
F+ LLG+G+F V + + + + VA+K+I Y+ A RV +K + +
Sbjct: 12 FKVGNLLGKGSFAGVYRAESIHSGLEVAIKMIDKKAMYK--AGMVQRVQNEVKIHCQLKH 69
Query: 349 YQCLLLREFFDYKNHICLVTDLYGRSVYDFMTNNGYARFPGSHVQAIGKQLVRSVCFLHD 408
L L +F+ N++ LV ++ + N F + + Q++ + +LH
Sbjct: 70 PSILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQIITGMLYLHS 129
Query: 409 LGIIHTDLKPENILICDETCVEQSLPMEIIDSLTERRKLASGGKRKILINPEVKLIDFGS 468
GI+H DL N+L+ N +K+ DFG
Sbjct: 130 HGILHRDLTLSNLLLTR--------------------------------NMNIKIADFGL 157
Query: 469 AV---FYNEYHPPVVSTRHYRAPEIVLGLGWSFPCDIWSIACVLVELVTG 515
A +E H + T +Y +PEI D+WS+ C+ L+ G
Sbjct: 158 ATQLKMPHEKHYTLCGTPNYISPEIATRSAHGLESDVWSLGCMFYTLLIG 207
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.320 0.136 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 40,997,247
Number of Sequences: 60738
Number of extensions: 1778386
Number of successful extensions: 9126
Number of sequences better than 1.0e-05: 488
Number of HSP's better than 0.0 without gapping: 89
Number of HSP's successfully gapped in prelim test: 401
Number of HSP's that attempted gapping in prelim test: 7839
Number of HSP's gapped (non-prelim): 1038
length of query: 699
length of database: 30,389,216
effective HSP length: 113
effective length of query: 586
effective length of database: 23,525,822
effective search space: 13786131692
effective search space used: 13786131692
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)