ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI6002 good S KOG2654 Function unknown Uncharacterized conserved protein
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI6002 2096499 2095696 -268
(268 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YGL174w [S] KOG2654 Uncharacterized conserved protein 112 7e-25
SPCC1620.10 [S] KOG2654 Uncharacterized conserved protein 79 7e-15
CE00289 [S] KOG2654 Uncharacterized conserved protein 69 5e-12
7301183 [S] KOG2654 Uncharacterized conserved protein 69 9e-12
Hs14249338 [S] KOG2654 Uncharacterized conserved protein 57 3e-08
YDL058w [U] KOG0946 ER-Golgi vesicle-tethering protein p115 50 4e-06
>YGL174w [S] KOG2654 Uncharacterized conserved protein
Length = 266
Score = 112 bits (279), Expect = 7e-25
Identities = 74/239 (30%), Positives = 127/239 (52%), Gaps = 36/239 (15%)
Query: 49 ANLITEENKKAASS-----NKTGKSLWKNLETEKLELVQHVDVDKKDDSKERMSSGAFAG 103
+ L E+ K +S + K++WKNLET +L + S+ + G
Sbjct: 45 STLQQEQEKSGVASFSKFDKQKSKNIWKNLETNELS-----------HAITHPSASSITG 93
Query: 104 LQTAEEMEKQIAEKEKLSMQKSGLLKKNQNTVYRDEKGKVIDGYEEELKLREKANLTAK- 162
++ ++++ A++ +++ K + T+YRD +G I +E+ K+ + + +K
Sbjct: 94 NESKNDLKEIRAQEPLVTVADKS---KTRKTIYRDAQGHKI---QEDSKIDDSSFSRSKY 147
Query: 163 -----VRKEEELKIRNIGEVQISKLD------RKTEKSALLSTEDPLNQ--GNTLRGTNT 209
+E+ LK N+G+VQ ++ +K + ++ L+ EDP + R T
Sbjct: 148 EDEKAAEREQYLKNLNMGDVQKLGINVDAHDKKKNQTASSLTIEDPAITFTHDKERTVKT 207
Query: 210 SLLGRRLYEKNFPENRFGIVPGYRWDGVDRSNGFETKWFAKSHDIADQKIKEQTTNREF 268
SLLGR+LY+K PENRF I+PG RWDGV RSNGFE KWFAK ++I ++K++ T ++
Sbjct: 208 SLLGRKLYDKPAPENRFAIMPGSRWDGVHRSNGFEEKWFAKQNEINEKKVQSYTLQEDY 266
>SPCC1620.10 [S] KOG2654 Uncharacterized conserved protein
Length = 305
Score = 79.0 bits (193), Expect = 7e-15
Identities = 64/231 (27%), Positives = 109/231 (46%), Gaps = 32/231 (13%)
Query: 41 RNIDIIDKANLITEENKKAASSNKTGKSLWKNLETEKLELVQHVDVDKKD--DSKERMSS 98
R+ID I + N+ NK A LWK + +++ V+ +++D D++
Sbjct: 74 RDIDAIYQ-NIEKTTNKPA--------QLWKAVGNDEV-----VESEQQDSHDAESIPQF 119
Query: 99 GAFAGLQTAEEMEKQIAEKEKLSMQKSGLLKKNQNTVYRDEKGKVID----GYEEELKLR 154
G G Q + E++ +EK S L+K++ TVYRD G+ ID E + KL+
Sbjct: 120 GLLTGKQVTFKAEERRKREEKSSNLDEEELRKSRETVYRDATGRRIDLVLARKEAKRKLK 179
Query: 155 EKANLTAKVRKEEE--LKIRNIGE----------VQISKLDRKTEKSALLSTEDPLNQGN 202
EK + +++++ +++R E V +++ + E + L N
Sbjct: 180 EKEEEARRQKEQQQGVVQVRQQKEYLKELERQKTVPLARYEDDPEYNKELKERSRWNDPA 239
Query: 203 TLRGTNTSLLGRRLYEKNFPENRFGIVPGYRWDGVDRSNGFETKWFAKSHD 253
TN + + Y+ P NRF I PG+RWDG+ R NGFE KWF + ++
Sbjct: 240 ASFLTNKPVSSKATYQGYAPPNRFNIRPGHRWDGIIRGNGFENKWFQRQNE 290
>CE00289 [S] KOG2654 Uncharacterized conserved protein
Length = 458
Score = 69.3 bits (168), Expect = 5e-12
Identities = 59/212 (27%), Positives = 98/212 (45%), Gaps = 41/212 (19%)
Query: 71 KNLETEKLELVQHVDVDKKDDSKERMSSGAFAGLQTAEEMEKQIAEKEKLSMQKSGLLKK 130
K+ + E+ + ++ + D ++ R G +GLQ+A ++++ E +KL + S + ++
Sbjct: 229 KSRKIEEPKKIKKEEPDSDTETSGRTLEGKRSGLQSARDLKE---ESDKLRAKNSKMFEE 285
Query: 131 NQ--------NTVYRDE--KGKVIDGYEEELKLREKANLTAKVRKEEELKIRNIGEVQIS 180
+TVYR + K K D E++ K + T +++ E+ K N G QI
Sbjct: 286 MDTSVSGRFADTVYRQKQTKKKGKDSEEDQAKKERETKKTEELK--EKYKSWNKGVAQIE 343
Query: 181 KLDRKTEKSALLSTE----------------------DPLNQGNTLRGTNTSLLGRRL-- 216
+ E+ A ++ E DP+ + +T++ L
Sbjct: 344 DRRAQLEEMARVAAEPMARARDDDAMNAHLKEVLHAADPMANMIQKKRRDTAIDRGELVY 403
Query: 217 --YEKNFPENRFGIVPGYRWDGVDRSNGFETK 246
Y +F NRFGI PGYRWDGVDRSNGFE K
Sbjct: 404 PSYHGHFVPNRFGIAPGYRWDGVDRSNGFEGK 435
>7301183 [S] KOG2654 Uncharacterized conserved protein
Length = 647
Score = 68.6 bits (166), Expect = 9e-12
Identities = 55/193 (28%), Positives = 87/193 (44%), Gaps = 43/193 (22%)
Query: 99 GAFAGLQTAEEMEKQIAEK--------EKLSMQKSGL----------------------- 127
G AGLQ A+ ++K+ E+ EK+S + SG
Sbjct: 444 GKKAGLQDAKSLKKETDERRRQEHELFEKMSSEISGRDGDVQVRSTRRKGHRARDAANED 503
Query: 128 -LKKNQNTVYRDEKGKVIDGYEEELKLRE--KANLTAKVRKEEELKIRNIGEVQISKLDR 184
++ + + +K ++ D + + LK E K+ L V + + R + + + R
Sbjct: 504 PAEQGRKEEHEKKKKELYDRWGKGLKQIEDHKSRLEEMVHEASKPVARYANDEDLDRHLR 563
Query: 185 KTEKSALLSTEDPL----NQGNTLRGTNTSLLGRRLYEKNFPENRFGIVPGYRWDGVDRS 240
+ E + +DP+ Q R + YE +FPENRFGI PGYRWDGVDRS
Sbjct: 564 EQEHA-----DDPMLEYMRQKRKKRDQQDNKPVMPKYEGSFPENRFGIRPGYRWDGVDRS 618
Query: 241 NGFETKWFAKSHD 253
NG+E +WF K ++
Sbjct: 619 NGYEQRWFDKQNE 631
>Hs14249338 [S] KOG2654 Uncharacterized conserved protein
Length = 619
Score = 57.0 bits (136), Expect = 3e-08
Identities = 54/197 (27%), Positives = 88/197 (44%), Gaps = 39/197 (19%)
Query: 96 MSSGAFAGLQTAEEMEKQ--IAEKEKLSMQKSGLLKKNQNTVYRDEKGKVIDGYEEELKL 153
M SGA GL + +Q + E+++ +M + + TV+RD+ G+ + E L+
Sbjct: 422 MYSGAKTGLVLTDIQREQQELKEQDQETMAFEAEFQYAE-TVFRDKSGRKRNLKLERLEQ 480
Query: 154 REKA-------------------------NLTAKVRKEEELKIRNIGEVQISKLDRKTEK 188
R KA N+ +++ ++ R I + + ++ R+ E+
Sbjct: 481 RRKAEKDSERDELYAQWGKGLAQSRQQQQNVEDAMKEMQKPLARYIDDEDLDRMLREQER 540
Query: 189 SALLSTEDPLN---QGNTLRGTNTSLLGRRLYEKNFPENRFGIVPGYRWDGVDRSNGFET 245
DP+ + N + + R P NRF I PGYRWDGVDRSNGFE
Sbjct: 541 EG-----DPMANFIKKNKAKENKNKKVRPRYSGPAPPPNRFNIWPGYRWDGVDRSNGFEQ 595
Query: 246 KWFAKSHDIADQKIKEQ 262
K FA+ +A +K E+
Sbjct: 596 KRFAR---LASKKAVEE 609
>YDL058w [U] KOG0946 ER-Golgi vesicle-tethering protein p115
Length = 1790
Score = 49.7 bits (117), Expect = 4e-06
Identities = 41/173 (23%), Positives = 83/173 (47%), Gaps = 16/173 (9%)
Query: 38 VTSRNIDIIDKANLITEENKKAASSNKTGKSLWKNLETEKLELVQHVDVDKKD----DSK 93
+ S ++ I + ++K S K+ + KNL+ EK +L+ ++ +KD SK
Sbjct: 1514 IESNETELKSSMETIRKSDEKLEQSKKSAEEDIKNLQHEKSDLISRINESEKDIEELKSK 1573
Query: 94 ERMSSGAFAGLQTAEEMEKQIAEKEKLSMQKSGLLKKNQNTVYRDEKGK--VIDGYEEEL 151
R+ + + + L+T ++ EK +++ +++ +LK + R+ K K I +EE
Sbjct: 1574 LRIEAKSGSELETVKQELNNAQEKIRINAEENTVLKSKLEDIERELKDKQAEIKSNQEEK 1633
Query: 152 KL---------REKANLTAKVRKEEELKIRNIGEVQISKLDRKTEKSALLSTE 195
+L +E + K +K EE + + + Q+ K + EK+ LL T+
Sbjct: 1634 ELLTSRLKELEQELDSTQQKAQKSEEERRAEVRKFQVEK-SQLDEKAMLLETK 1685
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.308 0.128 0.342
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,787,675
Number of Sequences: 60738
Number of extensions: 592950
Number of successful extensions: 2710
Number of sequences better than 1.0e-05: 6
Number of HSP's better than 0.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 2700
Number of HSP's gapped (non-prelim): 8
length of query: 268
length of database: 30,389,216
effective HSP length: 105
effective length of query: 163
effective length of database: 24,011,726
effective search space: 3913911338
effective search space used: 3913911338
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)