ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI6046 check: MH D KOG1166 Cell cycle control, cell division, chromosome partitioning Mitotic checkpoint serine/threonine protein kinase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI6046 2111913 2109037 -959
(959 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YGR188c [D] KOG1166 Mitotic checkpoint serine/threonine protein ... 725 0.0
SPCC1322.12c [D] KOG1166 Mitotic checkpoint serine/threonine pro... 266 9e-71
YJL013c [D] KOG1166 Mitotic checkpoint serine/threonine protein ... 225 2e-58
Hs4757878 [D] KOG1166 Mitotic checkpoint serine/threonine protei... 161 4e-39
7296964 [D] KOG1166 Mitotic checkpoint serine/threonine protein ... 156 1e-37
7302202 [D] KOG1166 Mitotic checkpoint serine/threonine protein ... 147 8e-35
CE06251_2 [D] KOG1166 Mitotic checkpoint serine/threonine protei... 122 3e-27
Hs20149509 [D] KOG1166 Mitotic checkpoint serine/threonine prote... 91 7e-18
YOL100w [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 69 5e-11
SPCC4G3.08 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 68 6e-11
At5g62310 [TR] KOG0606 Microtubule-associated serine/threonine k... 67 1e-10
YPL209c [D] KOG0580 Serine/threonine protein kinase 67 2e-10
At3g17850 [TR] KOG0606 Microtubule-associated serine/threonine k... 65 4e-10
Hs4505695 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 65 5e-10
7294566 [T] KOG0612 Rho-associated coiled-coil containing protei... 63 2e-09
SPCC18B5.11c [D] KOG0615 Serine/threonine protein kinase Chk2 an... 62 3e-09
YDR466w [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 60 2e-08
CE21025 [D] KOG0580 Serine/threonine protein kinase 60 2e-08
YDR490c [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 60 2e-08
CE05780 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 60 2e-08
CE20142 [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 59 4e-08
At2g25090 [T] KOG0583 Serine/threonine protein kinase 59 4e-08
At1g45160 [TR] KOG0606 Microtubule-associated serine/threonine k... 59 5e-08
At5g05510 [D] KOG1166 Mitotic checkpoint serine/threonine protei... 58 8e-08
7299536 [D] KOG0580 Serine/threonine protein kinase 58 8e-08
YBR028c [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 57 2e-07
At1g48490 [TR] KOG0606 Microtubule-associated serine/threonine k... 56 2e-07
SPBC725.06c [R] KOG0605 NDR and related serine/threonine kinases 56 3e-07
Hs4506737 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 56 3e-07
Hs14196445 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 56 3e-07
At2g45490 [D] KOG0580 Serine/threonine protein kinase 56 3e-07
YNR047w [R] KOG0610 Putative serine/threonine protein kinase 55 4e-07
SPAC24B11.11c [R] KOG0605 NDR and related serine/threonine kinases 55 5e-07
At1g01140 [T] KOG0583 Serine/threonine protein kinase 55 5e-07
YKL166c [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 54 9e-07
SPCC417.06c [R] KOG0605 NDR and related serine/threonine kinases 54 9e-07
SPCC320.12c [D] KOG0580 Serine/threonine protein kinase 54 9e-07
Hs4507273 [D] KOG0580 Serine/threonine protein kinase 54 9e-07
7295426 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 54 9e-07
At5g45820 [T] KOG0583 Serine/threonine protein kinase 54 1e-06
At2g26980 [T] KOG0583 Serine/threonine protein kinase 54 1e-06
YPL203w [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 54 2e-06
SPCC24B10.07 [RT] KOG0598 Ribosomal protein S6 kinase and relate... 54 2e-06
Hs14249562 [TR] KOG0606 Microtubule-associated serine/threonine ... 53 2e-06
At1g69220 [T] KOG0576 Mitogen-activated protein kinase kinase ki... 53 2e-06
Hs4759178 [D] KOG0580 Serine/threonine protein kinase 53 3e-06
CE25046 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 53 3e-06
CE22877 [D] KOG0575 Polo-like serine/threonine protein kinase 53 3e-06
Hs7657526 [T] KOG0603 Ribosomal protein S6 kinase 52 3e-06
ECU01g0630 [D] KOG0575 Polo-like serine/threonine protein kinase 52 3e-06
At3g46140 [T] KOG0198 MEKK and related serine/threonine protein ... 52 3e-06
At3g10660 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 52 3e-06
7300437 [TR] KOG0606 Microtubule-associated serine/threonine kin... 52 3e-06
Hs20428779_1 [T] KOG0587 Traf2- and Nck-interacting kinase and r... 52 3e-06
Hs20070247_2 [RT] KOG0598 Ribosomal protein S6 kinase and relate... 52 3e-06
YGR092w [R] KOG0605 NDR and related serine/threonine kinases 52 4e-06
Hs4885583 [T] KOG0612 Rho-associated coiled-coil containing prot... 52 4e-06
CE07599 [T] KOG0576 Mitogen-activated protein kinase kinase kina... 52 4e-06
YJL095w [T] KOG0198 MEKK and related serine/threonine protein ki... 52 6e-06
YCR091w [R] KOG0610 Putative serine/threonine protein kinase 52 6e-06
CE18169 [T] KOG0603 Ribosomal protein S6 kinase 52 6e-06
CE13014 [T] KOG0603 Ribosomal protein S6 kinase 52 6e-06
CE03979 [T] KOG0614 cGMP-dependent protein kinase 52 6e-06
7298652 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 52 6e-06
YNR031c [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and r... 51 8e-06
Hs9966875 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 51 8e-06
Hs6005814 [R] KOG0605 NDR and related serine/threonine kinases 51 8e-06
Hs5730055 [D] KOG0575 Polo-like serine/threonine protein kinase 51 8e-06
Hs4502553 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 51 8e-06
ECU07g0360 [D] KOG0580 Serine/threonine protein kinase 51 8e-06
CE21086 [D] KOG0590 Checkpoint kinase and related serine/threoni... 51 8e-06
CE13844 [D] KOG0608 Warts/lats-like serine threonine kinases 51 8e-06
At4g14580 [T] KOG0583 Serine/threonine protein kinase 51 8e-06
At3g51850 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 51 8e-06
SPCC576.15c [T] KOG0592 3-phosphoinositide-dependent protein kin... 51 1e-05
SPCC1450.11c [R] KOG0605 NDR and related serine/threonine kinases 51 1e-05
SPBC106.10 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 51 1e-05
Hs5453972 [T] KOG0694 Serine/threonine protein kinase 51 1e-05
At5g04510 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 51 1e-05
At3g27580 [R] KOG0610 Putative serine/threonine protein kinase 51 1e-05
>YGR188c [D] KOG1166 Mitotic checkpoint serine/threonine protein kinase
Length = 1021
Score = 725 bits (1872), Expect = 0.0
Identities = 439/1032 (42%), Positives = 587/1032 (56%), Gaps = 128/1032 (12%)
Query: 18 SLPQGRSATRVTSAMNKSLSSIYDTRLAFERDIHDTLDELDDPLQLFLEYINWIHDNYPS 77
+ PQ + V+S+ + S + T++A+E+ + + L+++DDPL LFL+Y+ WI +Y
Sbjct: 18 TFPQSKG---VSSSQKEQHSQLNQTKIAYEQRLLNDLEDMDDPLDLFLDYMIWISTSYIE 74
Query: 78 PTTR--QSGLPEIMERCIEYCKNIETYKNDVRYLKLWLQYIDLF-AVKLDEKREMFVYMM 134
+ Q L MERC+ Y +++ETY+ND R+LK+W+ YI+LF + E F YM
Sbjct: 75 VDSESGQEVLRSTMERCLIYIQDMETYRNDPRFLKIWIWYINLFLSNNFHESENTFKYMF 134
Query: 135 RLEIGDRLALYYESFSQLLINMDASGDALDLIDRGIEKKARPLRRLEQFKLSVQQAIQTR 194
IG +L+L+YE FS+LL N +A L++ G E RP RL + + + ++
Sbjct: 135 NKGIGTKLSLFYEEFSKLLENAQFFLEAKVLLELGAENNCRPYNRLLRSLSNYEDRLREM 194
Query: 195 GLTEQELPRSFSTFEIHGDLVLGRYRSEXXXXXXXXXXXXXXXSMSERSQ-NSLKSTGKL 253
+ E + S + G L+ YR+ R+ NS GK
Sbjct: 195 NIVENQNSVPDSRERLKGRLI---YRTAPFFIRKFLTSSLMTDDKENRANLNSNVGVGK- 250
Query: 254 QVFADNEEELQNDKFMLRQDLPTLPPYKTRNKENHTPAIPFKSGSTIAPLKQSNSFSQTD 313
A N + QD + +K + T + S + SN +
Sbjct: 251 --SAPN----------VYQDSIVVADFK-----SETERLNLNSSK-----QPSNQRLKNG 288
Query: 314 LDKIPVFRDDLGRATPVYKLIEVPGRKPEKIQTNFELLYPTADEEYCIEEVLALARNCYY 373
K ++ D PVYKLI PGRKPE+I NF L+YP DEE+ EE+LA+ + Y
Sbjct: 289 NKKTSIYADQKQSNNPVYKLINTPGRKPERIVFNFNLIYPENDEEFNTEEILAMIKGLYK 348
Query: 374 KEKNSSVKRHLEENNHENSKPMKKRGL-------------------------------QP 402
++ K+H E+ + + K KKR L P
Sbjct: 349 VQRRG--KKHTED--YTSDKNRKKRKLDVLVERRQDLPSSQPPVVPKSTRIEVFKDDDNP 404
Query: 403 KSPEYHK------VTTTSILPLKGDIEPDGLTGH--------SDGKSKSPTVTMFSKDAM 448
+HK TTTSILPLK + DG H + S+SPTVT FSKDA+
Sbjct: 405 SQSTHHKNTQVQVQTTTSILPLKPVV--DGNLAHETPVKPSLTSNASRSPTVTAFSKDAI 462
Query: 449 NEVYSMFNQSYHDMKNYSDHDDTTSGKFTMYENFQEDLTGKNSEDLTEVKQPMESKNLSA 508
NEV+SMFNQ Y D DDTT+ KF ++ENF ++ T KN EDLTEVK P +
Sbjct: 463 NEVFSMFNQHYSTPGALLDGDDTTTSKFNVFENFTQEFTAKNIEDLTEVKDPKQETVSQQ 522
Query: 509 STSANATPSRDQKQETTTPTFKSKLQDYMTPIQERTEPNF-------KTLLSQDDDITGE 561
+TS N T D+ + + + + + DYMTPI+E TE + K + +D +G+
Sbjct: 523 TTSTNET--NDRYERLSNSSTRPEKADYMTPIKETTETDVVPIIQTPKEQIRTEDKKSGD 580
Query: 562 SRRKSTNSVNTA-ESSPFLTQP----QRLL------DPSPSHQ----------------I 594
+ T +T +SSPFLTQP ++LL + S H I
Sbjct: 581 NTETQTQLTSTTIQSSPFLTQPEPQAEKLLQTAEHSEKSKEHYPTIIPPFTKIKNQPPVI 640
Query: 595 VENPXXXXXXXXXXXXXDPALASYPTYYEYSQQLKMSSLLKRIQKVSKNMNKNPIVDFKK 654
+ENP P L Y T+Y Y+Q+LKMSSLLK+I +VS+N NKNPIVDFKK
Sbjct: 641 IENPLSNNLRAKFLSEISPPLFQYNTFYNYNQELKMSSLLKKIHRVSRNENKNPIVDFKK 700
Query: 655 TNDLYCIRRELGEGGYATVYLAESSTGQLSALKVEKPASVWEFYILKQIERRVPDEAILK 714
T DLYCIR ELGEGGYATVYLAESS G L ALKVEKPASVWE+YI+ Q+E R+ ILK
Sbjct: 701 TGDLYCIRGELGEGGYATVYLAESSQGHLRALKVEKPASVWEYYIMSQVEFRLRKSTILK 760
Query: 715 SIINVSALHCFQDESYLVLNYANQGTILDLVNWERER---NGGALDECLCMFITVELMRV 771
SIIN SALH F DESYLVLNYA+QGT+LDL+N +RE+ G +DE LCMFITVELM+V
Sbjct: 761 SIINASALHLFLDESYLVLNYASQGTVLDLINLQREKAIDGNGIMDEYLCMFITVELMKV 820
Query: 772 LECIHDVGIIHGDIKPDNCMIRFQKVSH-LG-KYFANGENGWNRKGIYLIDFGRSFDLSL 829
LE IH+VGIIHGD+KPDNCMIR +K LG Y NGE+GW KGIYLIDFGRSFD++L
Sbjct: 821 LEKIHEVGIIHGDLKPDNCMIRLEKPGEPLGAHYMRNGEDGWENKGIYLIDFGRSFDMTL 880
Query: 830 FPLGTKFRSNWKTDQQDCPEMREQRPWSYEADYYGLAGVIFCMLFGHYIETVKVASNRYQ 889
P GTKF+SNWK DQQDC EMR +PWSYEADYYGLAGVI MLFG +IET+++ + R +
Sbjct: 881 LPPGTKFKSNWKADQQDCWEMRAGKPWSYEADYYGLAGVIHSMLFGKFIETIQLQNGRCK 940
Query: 890 LKSPLKRYWQQDIWNPLFDLLINSGAHDS---TLVSKLRHYRERMESYLERESALKLRNV 946
LK+P KRYW+++IW +FDLL+NSG + + K+ R +ES+LE+ + LRNV
Sbjct: 941 LKNPFKRYWKKEIWGVIFDLLLNSGQASNQALPMTEKIVEIRNLIESHLEQHAENHLRNV 1000
Query: 947 VLSLEADLEHLR 958
+LS+E +L H +
Sbjct: 1001 ILSIEEELSHFQ 1012
>SPCC1322.12c [D] KOG1166 Mitotic checkpoint serine/threonine protein kinase
Length = 1044
Score = 266 bits (681), Expect = 9e-71
Identities = 268/1033 (25%), Positives = 429/1033 (40%), Gaps = 174/1033 (16%)
Query: 43 RLAFERDIHDTLDELDDPLQLFLEYINWIHDNYPSPTTRQSGLPEI---MERCIEYCKNI 99
RLA ++ D ++ELDDP+ ++ I W+ + TR G+ + ++ I+Y +
Sbjct: 32 RLALFQEELDIIEELDDPVDVWYRCIEWLLE------TRFLGMETVNKMLDDAIQYLERC 85
Query: 100 ETYKNDVRYLKLWLQYIDLFAVKLDEKRE---MFVYMMRLEIGDRLALYYESFSQLLINM 156
NDVR+L + L I DE ++ F + IG LAL+YE + LLI M
Sbjct: 86 RFALNDVRHLLIQLAKIKQSYETPDELQQAAKQFYQLASKGIGLELALFYEEYGSLLIRM 145
Query: 157 DASGDALDLIDRGIEKKARPLRRLEQFKLSVQQAIQTRGLTEQELPRSFSTFEIHGDLVL 216
+A ++ + ++ARPL RL + E R++ H +
Sbjct: 146 QRWKEASEVFHAAVSREARPLVRLLR--------------NAAEFSRAYDLHNAHPSIHD 191
Query: 217 GRYRSEXXXXXXXXXXXXXXXSMSERSQNSLKSTGKLQVFADNEEELQNDKFMLRQDLPT 276
Y S S S QVF+D + Q+
Sbjct: 192 APYSSPFPPPRIVLGSKPVSSSTLPSKPKSF------QVFSDASSSRDS------QNASD 239
Query: 277 LPPYKTRNKENHTPAIP---------------------FKSG--------------STIA 301
LP K+ E +TP +P +++G S+I
Sbjct: 240 LPQAKSLESEANTPNLPLLYDKSSGKRVEYSAFNFLALYENGEERSMEECRAQRYLSSIQ 299
Query: 302 PLKQSNSFSQTDLDKIPVFRDDLG-RATPVYK--LIEVPGRKPEKIQTNFELLYPTADEE 358
P ++ ++I V D +P+YK + E + N+ + + E
Sbjct: 300 PNTAASFPKVVPKNEISVHHDSSSSNVSPIYKNPVAEQSDTPTRSLPKNYAYVAKSTSPE 359
Query: 359 YCI-EEVLALARNCYYKEKNSSVKRHLEE---------NNHENSKPMKKRGLQPKSPEYH 408
+ + V+ +A + +K S H + N S+ ++K P S +
Sbjct: 360 LKVFDTVMPVALSPKPAQKPPSPTIHTKAALADILDIFNQPLRSESLEKSSKSPISAQSS 419
Query: 409 KVTTTSILPLKGDIEPDG-----LTGHSDGKSKS--PTVTMFSKDAMNEVYSM-----FN 456
+ T PLK D LTG S + P++T SK+ +++YS F+
Sbjct: 420 YLGT----PLKNDENSSNSGATSLTGRSQEEHLDFIPSLTP-SKNYPSKIYSPNKNLDFS 474
Query: 457 QSYHDMKNYSDHDDTTSGKFT------MYENFQEDL-TGKNSEDLTEVKQPMESKNLSAS 509
+ + Y + ++ + K + QE+ TG S K+ E N+S +
Sbjct: 475 HTASKAETYKNSNELENVKREQPFSELLPSTLQEETATGTTSTTFANAKRRPEDSNISPT 534
Query: 510 T--SANATPSRDQKQETTTPTFKSKL--QDYMTPIQERTEPNFKTLLSQDDDITGESRRK 565
+ P Q + + S + YM + ++ + ++ + I E+ +
Sbjct: 535 NPKKLHTLPRSPQYSTVDSNSVLSPAMPKGYMFVNENQSMKHESSVSNPVATIPHENGKH 594
Query: 566 STNSVNTAESSPFLTQPQRLLDPSPSHQIVE----------------NPXXXXXXXXXXX 609
++ E PF + L P PS + NP
Sbjct: 595 DFGQLSPIEHKPFFPKNDDEL-PGPSGYLTMPYEEAMASLSNLPTLINPLDQSLRDLLFQ 653
Query: 610 XXDPALASYPTYYEYSQQLKM----SSLLKRIQKVS------KNMNKNPIVD-----FKK 654
P+L Y+E+ + S + +I+ + ++ N++ + F
Sbjct: 654 VLRPSLLRDKDYHEHETSFALVEHIESFVSKIKPKAGGPGRRRSSNRHSLDGPEFHLFYP 713
Query: 655 TNDLYCIRRELGEGGYATVYL----------------AESSTGQLSALKVEKPASVWEFY 698
N + +LG+G +A VYL AE++ +L ALK+E P S +EFY
Sbjct: 714 PNTNLSVISKLGQGAFAPVYLVKSKIETENGDVSQGGAENNESKLFALKIETPPSCFEFY 773
Query: 699 ILKQIERRVPDEAILKSIINVSALHCFQDESYLVLNYANQGTILDLVNWERER--NGGAL 756
+ +Q R+ SI+ V LH F D S+L+++Y QG+ILDLVN + +
Sbjct: 774 LTRQAMTRLKGLRETNSILPVHQLHMFHDTSHLLMDYRPQGSILDLVNSMHNSTFSSSGM 833
Query: 757 DECLCMFITVELMRVLECIHDVGIIHGDIKPDNCMIRFQKVSHLGK---YFANGENGWNR 813
DE L +F ++E +R++E +H IIHGD+K DN ++R + V+ Y G GW+
Sbjct: 834 DEILVVFFSIEFLRIIEALHTHKIIHGDLKADNALLRLETVADSEWSPIYSPEGLYGWSF 893
Query: 814 KGIYLIDFGRSFDLSLFPLGTKFRSNWKTDQQDCPEMREQRPWSYEADYYGLAGVIFCML 873
KGIYLIDFGR DLSLF KF ++W TD QDC EMRE RPW+Y+ DY+GLA +I+ ML
Sbjct: 894 KGIYLIDFGRGIDLSLFEEKVKFIADWDTDLQDCIEMREGRPWTYQIDYHGLAAIIYTML 953
Query: 874 FGHYIET---VKVASNRYQLKSPLKRYWQQDIWNPLFDLLINSGAHDS----TLVSKLRH 926
FG YIET V R L +KRYW QD+W+ LFDLL+N H S + +L
Sbjct: 954 FGQYIETRIEVINGQRRQVLTQRMKRYWNQDLWHRLFDLLLNPTLHVSEENLPMTEELSK 1013
Query: 927 YRERMESYLERES 939
R ME +L S
Sbjct: 1014 IRIEMEEWLVNHS 1026
>YJL013c [D] KOG1166 Mitotic checkpoint serine/threonine protein kinase
Length = 515
Score = 225 bits (574), Expect = 2e-58
Identities = 146/429 (34%), Positives = 231/429 (53%), Gaps = 33/429 (7%)
Query: 4 IHFDELEAQKENIISLPQGRSATRVTSAMNKSLSSIYDTRLAFERDIHDTLDELDDPLQL 63
I+F+E+E QKENI+ L +GRSA ++ A+++ L I + +FE+ + D L L DP+ L
Sbjct: 21 INFEEIETQKENILPLKEGRSAAALSKAIHQPLVEINQVKSSFEQRLIDELPALSDPITL 80
Query: 64 FLEYINWIHDNYP-SPTTRQSGLPEIMERCIEYCKNIETYKNDVRYLKLWLQYIDLFA-V 121
+LEYI W+++ YP ++QSG+ ++ERC+ + K++E Y+NDVR+LK+W YI+LF
Sbjct: 81 YLEYIKWLNNAYPQGGNSKQSGMLTLLERCLSHLKDLERYRNDVRFLKIWFWYIELFTRN 140
Query: 122 KLDEKREMFVYMMRLEIGDRLALYYESFSQLLINMDASGDALDLIDRGIEKKARPLRRLE 181
E R++F+YM+R IG LA +YE F+ LLI + A+ ++ GI+ KARP + LE
Sbjct: 141 SFMESRDIFMYMLRNGIGSELASFYEEFTNLLIQKEKFQYAVKILQLGIKNKARPNKVLE 200
Query: 182 QFKLSVQQAIQTRGLTEQELPRSFSTFEIHGDLVLGRYRSEXXXXXXXXXXXXXXXSMSE 241
+ ++ G +L S + VLG+ RSE ++
Sbjct: 201 D---RLNHLLRELGENNIQLGNEISMDSLE-STVLGKTRSEFVNRLELA---------NQ 247
Query: 242 RSQNSLKSTGKLQVFADNEE---EL--QNDKFMLRQDLPTLPPYKTRNKENHTPAIPFKS 296
+S + K VF D EE EL ++ + R RNKEN+ ++
Sbjct: 248 NGTSSDVNLTKNNVFVDGEESDVELFETPNRGVYRDGWENFDLKAERNKENNLRISLLEA 307
Query: 297 GSTIAPLKQSNSFSQTDL---DKIPVFRDDLGRATPVYKLIEVPGRKPEKIQTNFELLYP 353
+ + LKQ SQ +K+P+FRD +GR+ PVY++I +KPEKI NF+L+Y
Sbjct: 308 NTNLGELKQHEMLSQKKRPYDEKLPIFRDSIGRSDPVYQMINTKDQKPEKIDCNFKLIYC 367
Query: 354 TADE------EYCIEEVLALARNCYYKEKNSSVKRHLEENN--HENSKPMKKRGLQPKSP 405
+E E+ +EEVLA++RN Y + + + ++H E N E S K+ Q K P
Sbjct: 368 EDEESKGGRLEFSLEEVLAISRNVYKRVRTN--RKHPREANLGQEESANQKEAEAQSKRP 425
Query: 406 EYHKVTTTS 414
+ + S
Sbjct: 426 KISRKALVS 434
>Hs4757878 [D] KOG1166 Mitotic checkpoint serine/threonine protein kinase
Length = 1085
Score = 161 bits (408), Expect = 4e-39
Identities = 111/368 (30%), Positives = 181/368 (49%), Gaps = 35/368 (9%)
Query: 594 IVENPXXXXXXXXXXXXXDPALASYPTYYEYSQQLKMSSLLKRIQKVSKNMNKNPIVDFK 653
IV NP ++SYP +E+ Q K+ ++ P +F+
Sbjct: 737 IVGNPWDDKLIFKLLSGLSKPVSSYPNTFEW--QCKLPAI-------------KPKTEFQ 781
Query: 654 KTNDLYCIRRELGEGGYATVY------LAESSTGQLSALKVEKPASVWEFYILKQIERRV 707
+ L + LGEG +A VY L ++ Q LKV+KPA+ WEFYI Q+ R+
Sbjct: 782 LGSKLVYVHHLLGEGAFAQVYEATQGDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMERL 841
Query: 708 PDEAILKSIINVSALHCFQDESYLVLNYANQGTILDLVNWERERNGGALDECLCMFITVE 767
++ + + H FQ+ S LV + GT+L+ +N + + + L + +
Sbjct: 842 KP-SMQHMFMKFYSAHLFQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMR 900
Query: 768 LMRVLECIHDVGIIHGDIKPDNCMIRFQKVSHLGKYFANGENGWNRK-GIYLIDFGRSFD 826
++ ++E +HD IIHGDIKPDN + LG F ++ + G+ LID G+S D
Sbjct: 901 MLYMIEQVHDCEIIHGDIKPDNFI--------LGNGFLEQDDEDDLSAGLALIDLGQSID 952
Query: 827 LSLFPLGTKFRSNWKTDQQDCPEMREQRPWSYEADYYGLAGVIFCMLFGHYIETVKVASN 886
+ LFP GT F + +T C EM +PW+Y+ DY+G+A ++CMLFG Y++ VK
Sbjct: 953 MKLFPKGTIFTAKCETSGFQCVEMLSNKPWNYQIDYFGVAATVYCMLFGTYMK-VKNEGG 1011
Query: 887 RYQLKSPLKRYWQQDIWNPLFDLLIN-SGAHDSTLVSKLRHYRERM--ESYLERESALKL 943
+ + +R D+WN F +++N H + LR +++ + Y + AL+
Sbjct: 1012 ECKPEGLFRRLPHLDMWNEFFHVMLNIPDCHHLPSLDLLRQKLKKVFQQHYTNKIRALRN 1071
Query: 944 RNVVLSLE 951
R +VL LE
Sbjct: 1072 RLIVLLLE 1079
>7296964 [D] KOG1166 Mitotic checkpoint serine/threonine protein kinase
Length = 1099
Score = 156 bits (395), Expect = 1e-37
Identities = 93/289 (32%), Positives = 159/289 (54%), Gaps = 23/289 (7%)
Query: 659 YCIRRELGEGGYATVYLA-ESSTGQLSALKVEKPASVWEFYILKQIERRVPDEAILKSII 717
+ I +E+G G Y +VY A +S TG + ALK +KP + WE YI Q+ +R+ + +L ++
Sbjct: 814 FSIDKEVGRGSYGSVYKATDSRTGNVVALKYQKPPNTWEIYICDQVLKRIKEPEVLPGVM 873
Query: 718 NVSALHCFQDESYLVLNYANQGTILDLVNWERERNGGALDECLCMFITVELMRVLECIHD 777
++S + S + ++ G++LD+ N R+ + E L M + ++ +++ +H
Sbjct: 874 DISTAIIAPNASLIATEFSPFGSLLDINNKIRQATTKVMHESLVMHFSAQICNIVDHLHR 933
Query: 778 VGIIHGDIKPDNCMIRFQKVSHLGKYFANGENGWNRKGIYLIDFGRSFDLSLFPLG--TK 835
IIH DIKPDN ++ +V ++ + + LIDFG + D++LFP G TK
Sbjct: 934 QHIIHADIKPDNFLL--MRVPNVDSPLPS---------LRLIDFGCAIDMTLFPDGEKTK 982
Query: 836 FRSNWKTDQQDCPEMREQRPWSYEADYYGLAGVIFCMLFGHYIETVKVASNRYQLKSPLK 895
FR +TD C EM+E R WSYE D + +A + MLFG Y++ K S+ ++++ L
Sbjct: 983 FRKVVQTDGFTCIEMQEGRSWSYETDLFCIAATVHVMLFGDYMQPQKKGSS-WEIRQKLP 1041
Query: 896 RYWQQDIWNPLFDLLINSGA------HDSTLVSKLRHYRERMESYLERE 938
RY ++ +W F L+N A H+ L+ + Y RM+S L+++
Sbjct: 1042 RYLKKHVWTKFFGDLLNMQADKLPALHEMRLIFEEEAY--RMDSELQKQ 1088
>7302202 [D] KOG1166 Mitotic checkpoint serine/threonine protein kinase
Length = 1460
Score = 147 bits (371), Expect = 8e-35
Identities = 87/304 (28%), Positives = 154/304 (50%), Gaps = 15/304 (4%)
Query: 634 LKRIQKVSKNMNKNPIVDFKKTNDLYCIRRELGEGGYATVYLAES-STGQLSALKVEKPA 692
L Q V +P + N+ + + + +G+G Y +VY+ + +G+ ALK E+P
Sbjct: 1150 LPHCQLVGHVKRLHPNTHLEVHNEKFEVSKMIGKGAYGSVYVGKHLKSGKKVALKQERPT 1209
Query: 693 SVWEFYILKQIERRVPDEAILKSIINVSALHCFQDESYLVLNYANQGTILDLVNWERERN 752
+ WEFYI +I R+ E ++ S ++ + S + +++ G+++ + N +
Sbjct: 1210 NYWEFYICLEIHSRLTSEQMIPSYAHIDYALVGNNSSVYISEFSDYGSLIGVCNKVKSVT 1269
Query: 753 GGALDECLCMFITVELMRVLECIHDVGIIHGDIKPDNCMIRFQKVSHLGKYFANGENGWN 812
+DE + M ++ +++ +++ +H +GIIH DIKPDN ++ + N
Sbjct: 1270 NRNMDEYVVMHLSCQMLDIVDHLHAMGIIHADIKPDNFLLMKPICADP-----------N 1318
Query: 813 RKGIYLIDFGRSFDLSLFPLGTKFRSNWKTDQQDCPEMREQRPWSYEADYYGLAGVIFCM 872
+ LIDFG S D+ LFP F D C EMR RPW+Y+ D YGL V+ +
Sbjct: 1319 EVSLQLIDFGVSIDMKLFPDNQTFNYVHHDDLFKCIEMRTGRPWTYQLDLYGLVSVMHVL 1378
Query: 873 LFGHYIETV-KVASNRYQLKSPLKRYWQQDIWNPLFDLLINSGAHDSTLVSKLRHYRERM 931
LFG Y+E V + S + K+ + RY+Q+ +W +F L+N D + L+ R ++
Sbjct: 1379 LFGRYMEVVQRSPSTIWMPKTNVPRYFQRTMWENIFRTLLN--IRDCRTMPNLQQLRTQL 1436
Query: 932 ESYL 935
+ L
Sbjct: 1437 KCAL 1440
Score = 60.5 bits (145), Expect = 1e-08
Identities = 47/180 (26%), Positives = 95/180 (52%), Gaps = 14/180 (7%)
Query: 8 ELEAQKENIISLPQGRSATRVTSAMNKSLSSIYDTRLAFERDIHDTLDELD--DPLQLFL 65
+ + KENI L GR+ + + +++++ S+ LA + + + + DPL +
Sbjct: 2 DFDNAKENIQPLASGRNVSLLQASLSQD-STHGQELLAQRKQMEEEVRTYKGADPLGAWY 60
Query: 66 EYINWIHDNYPSPTTRQSGLPEIMERCIEYCKNIETYKNDVRYLKLWLQYIDLFAVKLDE 125
+I WI +YP+ + SGL ++ +C+ ++ E Y+ D R +KL++++++ K +
Sbjct: 61 TFICWIEQSYPAGGSG-SGLQTVLHQCLTKFEDDERYRQDKRLIKLFIKFME----KQKD 115
Query: 126 KREMFVYMMRLEIGDRLALYYESFSQLLINMDASGD---ALDLIDRGIEKKARPLRRLEQ 182
K E + M IG LA +Y +++ + D SG+ A ++ G+E +A PL L++
Sbjct: 116 KIEFYQQMYNNGIGTMLADFYIAWA---YSYDLSGNMRKADEIFRLGLECRAEPLEDLKE 172
>CE06251_2 [D] KOG1166 Mitotic checkpoint serine/threonine protein kinase
Length = 460
Score = 122 bits (305), Expect = 3e-27
Identities = 85/277 (30%), Positives = 139/277 (49%), Gaps = 19/277 (6%)
Query: 629 KMSSLLKRIQKVSKNMNKNPIV----DFKKTNDLYCIRRELGEGGYATVYLAESSTGQLS 684
K+ L++ Q + + + P + D + + + I+ +G+GGYA VY A + +
Sbjct: 129 KLMCLVRPPQNMHEFQERAPKIQALRDCEVSGEKLHIQTLIGQGGYAKVYRAVTDDQRTV 188
Query: 685 ALKVEKPASVWEFYILKQIERRVPD---EAILKS-IINVSALHCFQDESYLVLNYANQGT 740
A+K E P+ WE YI Q+ R+ D E + K I+ V + + S LV Y GT
Sbjct: 189 AVKYEVPSCSWEVYICDQMRNRLKDRGLELMAKCCIMEVMDAYVYSTASLLVNQYHEYGT 248
Query: 741 ILDLVNWERERNGGALDECLCMFITVELMRVLECIHDVGIIHGDIKPDNCMIRFQKVSHL 800
+L+ N ++ N + F+ ++ RV++ +H IIHGDIKPDN MI +
Sbjct: 249 LLEYANNMKDPNWH-----ITCFLITQMARVVKEVHASKIIHGDIKPDNFMITRKIDDKW 303
Query: 801 GKYFANGENGWNRKGIYLIDFGRSFDLSLFPL-GTKFRSNWKTDQQDCPEMREQRPWSYE 859
GK + + K +ID+GR+ D+ PL +F+ T+ DCPEM + R W+Y+
Sbjct: 304 GKDALMSNDSFVIK---IIDWGRAIDM--MPLKNQRFKGRAGTEAFDCPEMVDGRSWTYQ 358
Query: 860 ADYYGLAGVIFCMLFGHYIETVKVASNRYQLKSPLKR 896
ADY+G A + ++ G Y + + Y L +KR
Sbjct: 359 ADYFGFAATMAVVVAGKYAQLTGASVGDYSLNVDIKR 395
>Hs20149509 [D] KOG1166 Mitotic checkpoint serine/threonine protein kinase
Length = 1050
Score = 91.3 bits (225), Expect = 7e-18
Identities = 79/318 (24%), Positives = 139/318 (42%), Gaps = 22/318 (6%)
Query: 7 DELEAQKENIISLPQGRSATRVTSAMNKSLS---SIYDTRLAFERDIHDTLDELDDPLQL 63
DE E KEN+ L QGR + + A+ + + ++ + AFE +I +DPL +
Sbjct: 20 DEWELSKENVQPLRQGRIMSTLQGALAQESACNNTLQQQKRAFEYEIRFYTG--NDPLDV 77
Query: 64 FLEYINWIHDNYPSPTTRQSGLPEIMERCIEYCKNIETYKNDVRYLKLWLQYIDLFAVKL 123
+ YI+W NYP ++S + ++ER +E + + Y +D R+L LWL+ L
Sbjct: 78 WDRYISWTEQNYPQGG-KESNMSTLLERAVEALQGEKRYYSDPRFLNLWLKLGRL----C 132
Query: 124 DEKREMFVYMMRLEIGDRLALYYESFSQLLINMDASGDALDLIDRGIEKKARPLRRLEQF 183
+E +M+ Y+ IG LA +Y S+++ + A + GI++KA PL RL+
Sbjct: 133 NEPLDMYSYLHNQGIGVSLAQFYISWAEEYEARENFRKADAIFQEGIQQKAEPLERLQSQ 192
Query: 184 KLSVQQAIQTRGLTEQELPRSFSTFE--IHGDLVLGRYRSEXXXXXXXXXXXXXXXSMSE 241
Q + + L E FE + L +S+ ++
Sbjct: 193 HRQFQARVSRQTLLALEKEEEEEVFESSVPQRSTLAELKSK-GKKTARAPIIRVGGALKA 251
Query: 242 RSQN---------SLKSTGKLQVFADNEEELQNDKFMLRQDLPTLPPYKTRNKENHTPAI 292
SQN +++ ++ VF +N +E + P + P R KEN A
Sbjct: 252 PSQNRGLQNPFPQQMQNNSRITVFDENADEASTAELSKPTVQPWIAPPMPRAKENELQAG 311
Query: 293 PFKSGSTIAPLKQSNSFS 310
P+ +G ++ + N+ S
Sbjct: 312 PWNTGRSLEHRPRGNTAS 329
Score = 71.2 bits (173), Expect = 7e-12
Identities = 65/283 (22%), Positives = 130/283 (44%), Gaps = 23/283 (8%)
Query: 656 NDLYCIRRE-LGEGGYATVYLAESSTGQLSALKVEKPASVWEFYILKQIERRVPDEAILK 714
N+ YCI+RE L Y ++A ++ +L+ +KV W+FYI +++ R+ ++
Sbjct: 763 NEDYCIKREYLICEDYKLFWVAPRNSAELTVIKVSSQPVPWDFYINLKLKERLNED---- 818
Query: 715 SIINVSALHCFQDESYLVLNYANQGTILDLVNWERERNGGALDECLCMFITVELMRVLEC 774
+ + + +QD + Y N T+ DL+ ++ + + + I L+ ++E
Sbjct: 819 -FDHFCSCYQYQDGCIVWHQYINCFTLQDLL-----QHSEYITHEITVLIIYNLLTIVEM 872
Query: 775 IHDVGIIHGDIKPDNCMIRFQKVSHLGKYFANGENGWNRKGIYLIDFGRSFDLSLFPLGT 834
+H I+HGD+ P C+I ++ Y N N + + ++DF S DL + L
Sbjct: 873 LHKAEIVHGDLSP-RCLILRNRIH--DPYDCNK----NNQALKIVDFSYSVDLRV-QLDV 924
Query: 835 KFRSNWKTDQ-QDCPEMREQRPWSYEADYYGLAGVIFCMLFGHYIETVKVASNRYQLKSP 893
S ++T Q + ++ Y+ D +G+A + +LF +++ V + ++L
Sbjct: 925 FTLSGFRTVQILEGQKILANCSSPYQVDLFGIADLAHLLLFKEHLQ-VFWDGSFWKLSQN 983
Query: 894 LKRYWQQDIWNPLFDLLINSGAHDSTLVSKLRHYRERMESYLE 936
+ ++WN F ++N A+D VS L M +
Sbjct: 984 ISELKDGELWNKFFVRILN--ANDEATVSVLGELAAEMNGVFD 1024
>YOL100w [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 1081
Score = 68.6 bits (166), Expect = 5e-11
Identities = 72/263 (27%), Positives = 110/263 (41%), Gaps = 57/263 (21%)
Query: 633 LLKRIQKVSKNMNKNPIVDFKKTNDLYCIRRELGEGGYATVYLAES-STGQLSALKVEKP 691
+ K K KN+ K I DFK +G+G Y+TV LA S T + A KV
Sbjct: 160 IAKESSKAQKNIIKKGIKDFK-------FGSVIGDGAYSTVMLATSIDTKKRYAAKVLNK 212
Query: 692 ASVWEFYILKQIERRVPDEAILKSIIN--------VSALHCFQDES--YLVLNYANQGTI 741
Y+++Q ++V +I K+ + V FQDES Y +L YA G
Sbjct: 213 E-----YLIRQ--KKVKYVSIEKTALQKLNNSPSVVRLFSTFQDESSLYFLLEYAPNGDF 265
Query: 742 LDLVNWERERNGGALDECLCMFITVELMRVLECIHDVGIIHGDIKPDNCMIRFQKVSHLG 801
L L+ + G+LDE + +++ ++ +H GIIH DIKP+N ++
Sbjct: 266 LSLM-----KKYGSLDETCARYYAAQIIDAIDYLHSNGIIHRDIKPENILL--------- 311
Query: 802 KYFANGENGWNRKGIYLIDFG---------RSFDLSLFPLGTKFRSNWKTDQQDCPEMRE 852
+GE I L DFG S + L T+ +S T + PE+
Sbjct: 312 ----DGE-----MKIKLTDFGTAKLLNPTNNSVSKPEYDLSTRSKSFVGTAEYVSPELLN 362
Query: 853 QRPWSYEADYYGLAGVIFCMLFG 875
Y D + ++F M+ G
Sbjct: 363 DSFTDYRCDIWAFGCILFQMIAG 385
>SPCC4G3.08 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 436
Score = 68.2 bits (165), Expect = 6e-11
Identities = 63/217 (29%), Positives = 100/217 (46%), Gaps = 34/217 (15%)
Query: 665 LGEGGYATVYLA-ESSTGQLSALKVEKPASVWEFYILKQIERRVPDEAILKSIIN---VS 720
LG G Y V L + +TG+L A K K AS+ K +E+ + IL+ + +
Sbjct: 97 LGRGSYGKVLLVKQKNTGRLFAQKQLKKASI--VLRAKGLEQTKNERQILEEVRHPFICR 154
Query: 721 ALHCFQDES--YLVLNYANQGTILDLVNWERERNGGALDECLCMFITVELMRVLECIHDV 778
+ FQD YL+L YA G + + +R L E + F T EL L +H +
Sbjct: 155 LYYAFQDHDRLYLILQYAPGGELFSHLAEQR-----MLPEDVVAFYTAELTLALIHLHKL 209
Query: 779 GIIHGDIKPDNCMIRFQKVSHLGKYFANGENGWNRKGIYLIDFGRSFDLSLFPLGTKFRS 838
GI++ D+KP+NC++ A G I L DFG S + G RS
Sbjct: 210 GIVYRDLKPENCLLD-----------AEGH-------ILLTDFGLS---KVAENGADCRS 248
Query: 839 NWKTDQQDCPEMREQRPWSYEADYYGLAGVIFCMLFG 875
T++ PE+ ++P+ + D++ + +IF +L G
Sbjct: 249 FVGTEEYCAPEILLEQPYDHAVDWWSMGILIFDLLTG 285
>At5g62310 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1168
Score = 67.0 bits (162), Expect = 1e-10
Identities = 48/152 (31%), Positives = 76/152 (49%), Gaps = 14/152 (9%)
Query: 647 NPIVDFKKTNDLYCIRRELGEGGYATVYLAES-STGQLSALKVEKPASVWEFYILKQIER 705
NP + + + + I + + G + V+LA+ +TG L A+KV K A + +E
Sbjct: 742 NPRAKDRTSIEDFEIIKPISRGAFGRVFLAKKRATGDLFAIKVLKKADMIR---KNAVES 798
Query: 706 RVPDEAILKSIINVSALHCF-----QDESYLVLNYANQGTILDLVNWERERNGGALDECL 760
+ + IL S+ N + F ++ YLV+ Y N G + L+ RN G LDE +
Sbjct: 799 ILAERNILISVRNPFVVRFFYSFTCRENLYLVMEYLNGGDLFSLL-----RNLGCLDEDM 853
Query: 761 CMFITVELMRVLECIHDVGIIHGDIKPDNCMI 792
E++ LE +H V IIH D+KPDN +I
Sbjct: 854 ARIYIAEVVLALEYLHSVNIIHRDLKPDNLLI 885
>YPL209c [D] KOG0580 Serine/threonine protein kinase
Length = 367
Score = 66.6 bits (161), Expect = 2e-10
Identities = 65/240 (27%), Positives = 106/240 (44%), Gaps = 31/240 (12%)
Query: 641 SKNMNKNP-IVDFKKTN-DLYCIRRELGEGGYATVY-LAESSTGQLSALKVEKPASVWEF 697
SK +++N + FK + D + + ++LG+G + VY + STG + ALKV + + ++
Sbjct: 84 SKMIHENKKLPKFKSLSLDDFELGKKLGKGKFGKVYCVRHRSTGYICALKVMEKEEIIKY 143
Query: 698 YILKQIERRVPDEAILKSIINVSALHCFQDES--YLVLNYANQGTILDLVNWERERNGGA 755
+ KQ R V + L + F DE YL++ Y G + L+ R G
Sbjct: 144 NLQKQFRREVEIQTSLNHPNLTKSYGYFHDEKRVYLLMEYLVNGEMYKLL-----RLHGP 198
Query: 756 LDECLCMFITVELMRVLECIHDVGIIHGDIKPDNCMIRFQKVSHLGKYFANGENGWNRKG 815
++ L ++ L+ +H IIH DIKP+N +I F V
Sbjct: 199 FNDILASDYIYQIANALDYMHKKNIIHRDIKPENILIGFNNV------------------ 240
Query: 816 IYLIDFGRSFDLSLFPLGTKFRSNWKTDQQDCPEMREQRPWSYEADYYGLAGVIFCMLFG 875
I L DFG S + P + ++ T PEM E R + + D + L + F +L G
Sbjct: 241 IKLTDFGWSI---INPPENRRKTVCGTIDYLSPEMVESREYDHTIDAWALGVLAFELLTG 297
>At3g17850 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1263
Score = 65.5 bits (158), Expect = 4e-10
Identities = 47/160 (29%), Positives = 82/160 (50%), Gaps = 15/160 (9%)
Query: 640 VSKNMNKNPIVDFKKTN-DLYCIRRELGEGGYATVYLAES-STGQLSALKVEKPASVWEF 697
V +++ +P+ +T+ D + I + + G + V+LA+ +TG L A+KV K A +
Sbjct: 870 VVRSLRTSPVHPRDRTSIDDFEIIKPISRGAFGRVFLAKKRTTGDLFAIKVLKKADMIR- 928
Query: 698 YILKQIERRVPDEAILKSIINVSALHCF-----QDESYLVLNYANQGTILDLVNWERERN 752
+E + + IL ++ N + F +D YLV+ Y N G + L+ RN
Sbjct: 929 --KNAVESILAERDILINVRNPFVVRFFYSFTCRDNLYLVMEYLNGGDLYSLL-----RN 981
Query: 753 GGALDECLCMFITVELMRVLECIHDVGIIHGDIKPDNCMI 792
G L+E + E++ LE +H G++H D+KPDN +I
Sbjct: 982 LGCLEEDIVRVYIAEVVLALEYLHSEGVVHRDLKPDNLLI 1021
>Hs4505695 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 556
Score = 65.1 bits (157), Expect = 5e-10
Identities = 59/226 (26%), Positives = 98/226 (43%), Gaps = 26/226 (11%)
Query: 653 KKTNDLYCIRRELGEGGYATVYLA-ESSTGQLSALKVEKPASVWEFYILKQIERRVPDEA 711
KK + + + LGEG ++TV LA E +T + A+K+ + + + + + R +
Sbjct: 76 KKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMS 135
Query: 712 ILKSIINVSALHCFQDES--YLVLNYANQGTILDLVNWERERNGGALDECLCMFITVELM 769
L V FQD+ Y L+YA G +L + R G+ DE F T E++
Sbjct: 136 RLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYI-----RKIGSFDETCTRFYTAEIV 190
Query: 770 RVLECIHDVGIIHGDIKPDNCMIRFQKVSHLGKYFANGENGWNRKGIYLIDFGRSFDLSL 829
LE +H GIIH D+KP+N ++ I + DFG + LS
Sbjct: 191 SALEYLHGKGIIHRDLKPENILLN------------------EDMHIQITDFGTAKVLSP 232
Query: 830 FPLGTKFRSNWKTDQQDCPEMREQRPWSYEADYYGLAGVIFCMLFG 875
+ S T Q PE+ ++ +D + L +I+ ++ G
Sbjct: 233 ESKQARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAG 278
>7294566 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1252
Score = 62.8 bits (151), Expect = 2e-09
Identities = 51/173 (29%), Positives = 85/173 (48%), Gaps = 25/173 (14%)
Query: 632 SLLKRIQKVSKNMNK-NPIVD----FKKTNDLYCIRRELGEGGYATVYLA-ESSTGQLSA 685
+L KR + +++ +NK PI++ + D + I+ +G+G + V+L E T + A
Sbjct: 81 TLKKRDRNIAEFVNKFRPIIEETRKLRVNADDFLIKTLIGQGYFGNVHLVVERQTNDIYA 140
Query: 686 LKVEKPASVWEFYILKQIERRVPDEAILKSIIN----VSALHCFQDES--YLVLNYANQG 739
+K K + V +V +E + SI N ++ + FQD YLV+ Y G
Sbjct: 141 MKKIKKSVV--------TTSQVKEERDIMSIRNSEWLINLQYAFQDNDNLYLVMEYMPGG 192
Query: 740 TILDLVNWERERNGGALDECLCMFITVELMRVLECIHDVGIIHGDIKPDNCMI 792
+L L++ G DE L F EL L +H++G +H DIKP+N +I
Sbjct: 193 DLLSLMS-----RHGPFDEDLARFYLAELTVALHTLHEMGYVHRDIKPENILI 240
>SPCC18B5.11c [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 460
Score = 62.4 bits (150), Expect = 3e-09
Identities = 50/165 (30%), Positives = 81/165 (48%), Gaps = 23/165 (13%)
Query: 639 KVSKNMNKNPIVDFKKTNDLYCIRRELGEGGYATVYLA-ESSTGQLSALKVEKPASVWEF 697
K S++ KN I K N Y I R LG G +A V LA E ++G+ A+K+ +
Sbjct: 150 KHSRDSQKNMI---KSENSHYEIIRTLGSGTFAVVKLAVEVNSGKWYAIKIINKRKI--- 203
Query: 698 YILKQIERRVPDEA-----ILKSIINVSALHCFQ-----DESYLVLNYANQGTILDLVNW 747
+L E+R + ILKS+ + + C + DE ++V+ Y G ++D +
Sbjct: 204 -LLTSSEKRATEMFQREIDILKSLHHPGVVQCHEIFENDDELFIVMEYVEGGDLMDFLI- 261
Query: 748 ERERNGGALDECLCMFITVELMRVLECIHDVGIIHGDIKPDNCMI 792
G++DE C + +L+ L +H G+ H DIKP+N +I
Sbjct: 262 ----ANGSIDEQDCKPLLKQLLETLLHLHKQGVTHRDIKPENILI 302
>YDR466w [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 898
Score = 60.1 bits (144), Expect = 2e-08
Identities = 68/253 (26%), Positives = 109/253 (42%), Gaps = 61/253 (24%)
Query: 653 KKTNDLYCIRRELGEGGYATVYLA--ESSTGQLSALKVEKPASVWEFYILKQIERRVPDE 710
K++ + + ELG G Y+TV+ A + S ++ A+KV +I+K E +V
Sbjct: 5 KRSPHDFIFKEELGHGSYSTVFKALDKKSPNKIYAIKVCSKK-----HIIK--EAKVKYV 57
Query: 711 AILKSIINVSA----------LHCFQDES--YLVLNYANQGTILDLVNWERERNGGALDE 758
I K+ +N+ A + F DE Y VL++A G +L L++ G ++
Sbjct: 58 TIEKNTMNLLAQKHHAGIIKLYYTFHDEENLYFVLDFAPGGELLSLLH-----KMGTFND 112
Query: 759 CLCMFITVELMRVLECIHDVGIIHGDIKPDNCMIRFQKVSHLGKYFANGENGWNRKG-IY 817
T +L+ LE IH GIIH D+KP+N ++ +R G +
Sbjct: 113 IWTRHFTAQLIDALEFIHSHGIIHRDLKPENVLL-------------------DRDGRLM 153
Query: 818 LIDFG--RSFDLSLFPLGTKFR--SNWKTDQQDC-----------PEMREQRPWSYEADY 862
+ DFG + D SL KF SN D Q+C PE+ Y +D
Sbjct: 154 ITDFGAAATIDPSLSGDSAKFNSDSNGSKDNQNCASFVGTAEYVSPELLLYNQCGYGSDI 213
Query: 863 YGLAGVIFCMLFG 875
+ L +I+ + G
Sbjct: 214 WALGCMIYQFVQG 226
>CE21025 [D] KOG0580 Serine/threonine protein kinase
Length = 326
Score = 60.1 bits (144), Expect = 2e-08
Identities = 52/223 (23%), Positives = 102/223 (45%), Gaps = 28/223 (12%)
Query: 657 DLYCIRRELGEGGYATVYLA-ESSTGQLSALKVEKPASVWEFYILKQIERRVPDEAILKS 715
D + + R LG+G + V+++ E T ++ ALKV + + + Q++R + + L+
Sbjct: 42 DDFDVGRPLGKGKFGNVFISREKKTKRIIALKVLFKTQLLQLGVSHQLKREIEIQYHLRH 101
Query: 716 IINVSALHCFQDES--YLVLNYANQGTILDLVNWERERNGGALDECLCMFITVELMRVLE 773
++ F D+ +++L+YA++G +L N + + G ++E + +L L
Sbjct: 102 PNILTLYGYFHDDKRVFVILDYASRG---ELFNVLQSQPGHKVNEVIAGRFVRQLANALH 158
Query: 774 CIHDVGIIHGDIKPDNCMIRFQKVSHLGKYFANGENGWNRKGIYLIDFGRSFDLSLFPLG 833
H G+IH DIKP+N ++ ++ + L DFG S+
Sbjct: 159 YCHSKGVIHRDIKPENLLLD------------------SKLNLKLADFG----WSVVADH 196
Query: 834 TKFRSNWKTDQQDCPEMREQRPWSYEADYYGLAGVIFCMLFGH 876
+K + T PEM +P + D + + ++F ML G+
Sbjct: 197 SKRHTLCGTMDYLAPEMVSNQPHDFNVDIWAIGILLFEMLVGY 239
>YDR490c [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 766
Score = 59.7 bits (143), Expect = 2e-08
Identities = 46/162 (28%), Positives = 83/162 (50%), Gaps = 24/162 (14%)
Query: 639 KVSKNMNKNPIVDFKKTNDLYCIRRELGEGGYATVYLAES-STGQLSALKVEKPASVWEF 697
+++K++ K I DFK +LG+G Y++V LA + +G+ A+KV E+
Sbjct: 112 ELTKHVVKMGIKDFK-------FGEQLGDGSYSSVVLATARDSGKKYAVKVLSK----EY 160
Query: 698 YILKQIERRVPDEAILKSIIN-----VSALHCFQDES--YLVLNYANQGTILDLVNWERE 750
I ++ + V E + +N FQDE+ Y +L YA G L L+
Sbjct: 161 LIRQKKVKYVTVEKLALQKLNGTKGIFKLFFTFQDEASLYFLLEYAPHGDFLGLI----- 215
Query: 751 RNGGALDECLCMFITVELMRVLECIHDVGIIHGDIKPDNCMI 792
+ G+L+E + +++ ++ +H++GIIH DIKP+N ++
Sbjct: 216 KKYGSLNETCARYYASQIIDAVDSLHNIGIIHRDIKPENILL 257
>CE05780 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 336
Score = 59.7 bits (143), Expect = 2e-08
Identities = 61/274 (22%), Positives = 122/274 (44%), Gaps = 55/274 (20%)
Query: 621 YYEYSQQLKMSSLLKRIQKVSKNMNKNPIVDFKKTNDLYCIRRELGEGGYATVYLAE-SS 679
Y+ +S++ + ++ K IQ+V D +K ++ I +G+G +++V+L
Sbjct: 28 YFTFSKRTLLENVSKWIQRVDGRQ------DIEKQYEIGAI---IGKGNFSSVHLTRRKE 78
Query: 680 TGQLSALKVEKPASVWEFY---ILKQIERR--------VPDEAILKSIIN----VSALHC 724
G ALKV +++ + +Q+E+R V +E + S+I +S +
Sbjct: 79 DGTKCALKVRYQSTLQFSFPSKFFQQVEKRAMRGKCFFVDNEVEMLSLIQHDHIISIIDA 138
Query: 725 FQDES--YLVLNYANQGTILDLVNWERERNGGALDECLCMFITVELMRVLECIHDVGIIH 782
F E+ ++V +A G + + + R G ++E IT+++ L +H+ ++H
Sbjct: 139 FSTENQYFIVFEHAQYGDLYETI-----RKNGRIEEPDAAIITLQVASALNYLHERNVVH 193
Query: 783 GDIKPDNCMIRFQKVSHLGKYFANGENGWNRKGIYLIDFGRSFDLSLFPLGTKFRSNWKT 842
D+KP+N ++ ++ + L DFG L+ LG +R T
Sbjct: 194 RDVKPENLLL------------------VDKFSVKLCDFG----LACHILGPLYRI-CGT 230
Query: 843 DQQDCPEMREQRPWSYEADYYGLAGVIFCMLFGH 876
PE+ + +S D + L V++ ML G+
Sbjct: 231 PTYCAPEVLRETGYSTRCDIWSLGVVLYVMLVGY 264
>CE20142 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 320
Score = 58.9 bits (141), Expect = 4e-08
Identities = 57/220 (25%), Positives = 95/220 (42%), Gaps = 45/220 (20%)
Query: 659 YCIRRELGEGGYATVYLA-----ESSTGQLSALKVEKPASVWEFYILKQIERRVPDEAIL 713
Y + +E+GEG ++TVYLA ++ ALK+ + + ++ I R A++
Sbjct: 26 YSVEKEVGEGSFSTVYLARRKEPKNDENPEVALKICLKRLILKNKMVPYIHREKEALALI 85
Query: 714 KSIIN-----VSALHCFQDES--YLVLNYANQGTILDLVNWERERNGGALDECLCMFITV 766
N V+ FQD Y VL YA G + L+ + + D +
Sbjct: 86 SREENAHPGIVTLYATFQDSESLYFVLEYAKYGDLCTLMQKQPDSKFNVADS---RYYAA 142
Query: 767 ELMRVLECIHDVGIIHGDIKPDNCMIRFQKVSHLGKYFANGENGWNRKGIYLIDFGRSFD 826
L+ LE IH +GIIH D+K DN +++ ++G I L DFG S
Sbjct: 143 NLLSALEHIHKLGIIHRDVKADNLLVK-----------SDGR-------IMLTDFGSS-- 182
Query: 827 LSLFPLGTKFRSNWKTDQQDCPEMREQRPWSYEADYYGLA 866
KF S+++ Q++ + E++P + + G A
Sbjct: 183 --------KFLSDYQKIQEN--PVEEEQPTGRRSSFVGTA 212
>At2g25090 [T] KOG0583 Serine/threonine protein kinase
Length = 469
Score = 58.9 bits (141), Expect = 4e-08
Identities = 41/140 (29%), Positives = 74/140 (52%), Gaps = 9/140 (6%)
Query: 657 DLYCIRRELGEGGYATVYLA-ESSTGQLSALKVEKPASVWEFY-ILKQIERRVPDEAILK 714
D Y I R LG G +A VY E STG A+KV K V++ +++QIER + +L+
Sbjct: 13 DKYNIGRLLGTGNFAKVYHGTEISTGDDVAIKVIKKDHVFKRRGMMEQIEREIAVMRLLR 72
Query: 715 --SIINVSALHCFQDESYLVLNYANQGTILDLVNWERERNGGALDECLCMFITVELMRVL 772
+++ + + + + + V+ Y N G + ++++ + G L E L +L+ +
Sbjct: 73 HPNVVELREVMATKKKIFFVMEYVNGGELFEMIDRD-----GKLPEDLARKYFQQLISAV 127
Query: 773 ECIHDVGIIHGDIKPDNCMI 792
+ H G+ H DIKP+N ++
Sbjct: 128 DFCHSRGVFHRDIKPENLLL 147
>At1g45160 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1067
Score = 58.5 bits (140), Expect = 5e-08
Identities = 63/238 (26%), Positives = 101/238 (41%), Gaps = 33/238 (13%)
Query: 657 DLYCIRRELGEGGYATVYLAES-STGQLSALKVEKPASVWEFYILKQIERRVPDEAILKS 715
D + I + + G + V+LA +TG A+KV K + IER + + IL +
Sbjct: 668 DDFEIIKPISRGAFGKVFLARKRTTGDFFAIKVLKKLDMIR---KNDIERILQERNILIT 724
Query: 716 IINVSALHCF-----QDESYLVLNYANQGTILDLVNWERERNGGALDECLCMFITVELMR 770
+ + F +D YLV+ Y N G + L+ + G LDE + EL+
Sbjct: 725 VRYPFLVRFFYSFTCRDNLYLVMEYLNGGDLYSLL-----QKVGCLDEEIARIYIAELVL 779
Query: 771 VLECIHDVGIIHGDIKPDNCMIRFQKVSHLGKYFANGENGWNRKGIY--LIDF-GRSFDL 827
LE +H + I+H D+KPDN +I + L + G ++ G+ ID G D+
Sbjct: 780 ALEYLHSLKIVHRDLKPDNLLIAYNGHIKLTDF------GLSKIGLINNTIDLSGHESDV 833
Query: 828 SLFPLGTKFRSNWK----------TDQQDCPEMREQRPWSYEADYYGLAGVIFCMLFG 875
S F+ N + T PE+ Y AD++ V+F +L G
Sbjct: 834 SPRTNSHHFQKNQEEERIRHSAVGTPDYLAPEILLGTEHGYAADWWSAGIVLFELLTG 891
>At5g05510 [D] KOG1166 Mitotic checkpoint serine/threonine protein kinase
Length = 471
Score = 57.8 bits (138), Expect = 8e-08
Identities = 32/124 (25%), Positives = 65/124 (51%), Gaps = 5/124 (4%)
Query: 59 DPLQLFLEYINWIHDNYPSPTTRQSGLPEIMERCIEYCKNIETYKNDVRYLKLWLQYIDL 118
D L ++ + + ++ PS + LP +++C E ++ + YKND RY+++WLQ +D
Sbjct: 26 DHLLPWIRGVKKMKESLPSQILNEK-LPRFLQKCAESFESDKRYKNDSRYIRVWLQLMDF 84
Query: 119 FAVKLDEKREMFVYMMRLEIGDRLALYYESFSQLLINMDASGDALDLIDRGIEKKARPLR 178
+D+ R + M IG + +L+Y++++ M DA + G++ A P+
Sbjct: 85 ----VDDPRALLRTMEAKSIGTKRSLFYQAYALHYEKMKRFEDAEKMYRLGVQNLAEPMD 140
Query: 179 RLEQ 182
L++
Sbjct: 141 ELQK 144
>7299536 [D] KOG0580 Serine/threonine protein kinase
Length = 411
Score = 57.8 bits (138), Expect = 8e-08
Identities = 84/367 (22%), Positives = 140/367 (37%), Gaps = 39/367 (10%)
Query: 516 PSRDQKQETTTPTFKSKLQDYMTPIQERTEPNFKTLLSQDDDITGESRRKSTNSVNTAES 575
P R ++ + L P E P K L + + +NS+ ++E
Sbjct: 16 PHRMPEKSAAVHNMQKNLLLGKKPNSENMAPASKPLPGSSGALIRKPGLGGSNSIASSEG 75
Query: 576 SPFLTQPQRLLDPSPSHQIVENPXXXXXXXXXXXXXDPALASYPTYYEYSQQLKMSSLLK 635
+ F + + S P P AS E S++L +S
Sbjct: 76 NNFQKPMVPSVKKTTSEFAAPAPVAPIKKPESLSKQKPTAASS----ESSKELGAASSSA 131
Query: 636 RIQKV-SKNMNKNPIVDFKKTNDL--YCIRRELGEGGYATVYLAESSTGQ-LSALKVEKP 691
+K ++ + P KKT +L + I R LG G + VYLA Q + ALKV
Sbjct: 132 EKEKTKTETQPQKP----KKTWELNNFDIGRLLGRGKFGNVYLAREKESQFVVALKVLFK 187
Query: 692 ASVWEFYILKQIERRVPDEAILKSIINVSALHCFQDES--YLVLNYANQGTILDLVNWER 749
+ E + Q+ R + ++ L+ + F D+ YL+L YA QGT+ + + +
Sbjct: 188 RQIGESNVEHQVRREIEIQSHLRHPHILRLYAYFHDDVRIYLILEYAPQGTLFNALQAQP 247
Query: 750 ERNGGALDECLCMFITVELMRVLECIHDVGIIHGDIKPDNCMIRFQKVSHLGKYFANGEN 809
+ DE L L +H+ IIH DIKP+N ++ + V + +
Sbjct: 248 MKR---FDERQSATYIQALCSALLYLHERDIIHRDIKPENLLLGHKGVLKIADF------ 298
Query: 810 GWNRKGIYLIDFGRSFDLSLFPLGTKFRSNWKTDQQDCPEMREQRPWSYEADYYGLAGVI 869
GW+ + S ++L T PEM + +P + D + L +
Sbjct: 299 GWS------VHEPNSMRMTL----------CGTVDYLPPEMVQGKPHTKNVDLWSLGVLC 342
Query: 870 FCMLFGH 876
F +L GH
Sbjct: 343 FELLVGH 349
>YBR028c [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 525
Score = 56.6 bits (135), Expect = 2e-07
Identities = 71/313 (22%), Positives = 120/313 (37%), Gaps = 99/313 (31%)
Query: 640 VSKNMNKNPIV----DFKKTNDLYCIRRELGEGGYATVYLAES-STGQLSALKVEKPASV 694
+S N+ +N + DFK R LG+G Y V L + +T +L A+K + A +
Sbjct: 112 ISSNIGENELSRNLHDFKPV-------RVLGQGAYGKVLLVKDVNTSKLYAMKQLRKAEI 164
Query: 695 W-----------------------EFYILKQIERRVPDEAILKSIIN---VSALHCFQDE 728
+ + K++ER + +IL I + V + F D
Sbjct: 165 LISQTATDSKREDEDKNDGNNNDNDDGLSKRLERTFAERSILSEIEHPNIVKLFYSFHDN 224
Query: 729 S--YLVLNYANQGTILDLVNWERERNGGALDECLCMFITVELMRVLECIHDVGIIHGDIK 786
S YL+L Y G + + + G LDE F E+ L +H G+++ D+K
Sbjct: 225 SKLYLLLQYIPGGEL-----FYHLKEHGTLDETTVSFYAAEISCALRFLHTKGVVYRDLK 279
Query: 787 PDNCMIRFQKVSHLGKYFANGENGWNRKG-IYLIDFGRSFDLSLFPLGTKFRSNWKTDQQ 845
P+NC++ N++G + L DFG L K ++ D++
Sbjct: 280 PENCLL-------------------NQRGHLVLTDFG---------LSKKSANDSAVDEE 311
Query: 846 D-----------------CPEMREQRPWSYEADYYGLAGVIFCMLFG--------HYIET 880
D PE+ + +S D+Y L +++ ML G H +
Sbjct: 312 DPENVNALYSIIGTPEYCAPEILLGKAYSQNCDWYSLGCLLYDMLVGKPPYTGSNHKVII 371
Query: 881 VKVASNRYQLKSP 893
K+ N+ K P
Sbjct: 372 NKIQQNKQGPKIP 384
>At1g48490 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1244
Score = 56.2 bits (134), Expect = 2e-07
Identities = 39/139 (28%), Positives = 66/139 (47%), Gaps = 8/139 (5%)
Query: 657 DLYCIRRELGEGGYATVYLA-ESSTGQLSALKVEKPASVWEFYILKQI--ERRVPDEAIL 713
D + + + + G + V LA +++TG L A+KV + A + ++ I ER + A
Sbjct: 826 DDFEVMKSISRGAFGHVILARKNTTGDLFAIKVLRKADMIRKNAVESILAERDILINARN 885
Query: 714 KSIINVSALHCFQDESYLVLNYANQGTILDLVNWERERNGGALDECLCMFITVELMRVLE 773
++ + YLV+ Y N G ++ R G LDE E++ LE
Sbjct: 886 PFVVRFFYSFTCSENLYLVMEYLNGGDFYSML-----RKIGCLDEANARVYIAEVVLALE 940
Query: 774 CIHDVGIIHGDIKPDNCMI 792
+H G++H D+KPDN +I
Sbjct: 941 YLHSEGVVHRDLKPDNLLI 959
>SPBC725.06c [R] KOG0605 NDR and related serine/threonine kinases
Length = 1032
Score = 55.8 bits (133), Expect = 3e-07
Identities = 49/175 (28%), Positives = 84/175 (48%), Gaps = 12/175 (6%)
Query: 657 DLYCIRRELGEGGYATVYLAES-STGQLSALKVEKPASVWEFYILKQIERRVPDEAILKS 715
D + + +E+ G Y VYLA+ S+G+ ALK+ +S+ +K + + I +
Sbjct: 526 DEFILLKEINRGAYGRVYLAKKRSSGKYFALKMIPKSSLDSLKKIKGLLLEKRNMHIQRY 585
Query: 716 IIN-VSALHCFQDESYL--VLNYANQGTILDLVNWERERNGGALDECLCMFITVELMRVL 772
N V + F YL V++Y N G L+ ++ G ++ +C + EL+ +
Sbjct: 586 GPNTVKLYYAFDSGDYLCLVMDYFNGGDCETLI----QKLGPLPEQWVCQY-AAELLNAI 640
Query: 773 ECIHDVGIIHGDIKPDNCMIRFQKVSHLG-KYFANGENGWNRKGIYLIDFGRSFD 826
E +H GIIH DIKP N ++ + H+ F EN +K +Y + SF+
Sbjct: 641 ELLHQDGIIHHDIKPANMLV--DETGHIRLTDFGLSENVEEKKEVYKLTKRMSFE 693
>Hs4506737 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 525
Score = 55.8 bits (133), Expect = 3e-07
Identities = 42/142 (29%), Positives = 74/142 (51%), Gaps = 16/142 (11%)
Query: 663 RELGEGGYATVY----LAESSTGQLSALKVEKPASVW---EFYILKQIERRVPDEAILKS 715
R LG+GGY V+ + ++TG++ A+KV K A + + + ER + +E +K
Sbjct: 95 RVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTKAERNILEE--VKH 152
Query: 716 IINVSALHCFQD--ESYLVLNYANQGTILDLVNWERERNGGALDECLCMFITVELMRVLE 773
V ++ FQ + YL+L Y + G + + ER G +++ C ++ E+ L
Sbjct: 153 PFIVDLIYAFQTGGKLYLILEYLSGGELF----MQLEREGIFMEDTACFYLA-EISMALG 207
Query: 774 CIHDVGIIHGDIKPDNCMIRFQ 795
+H GII+ D+KP+N M+ Q
Sbjct: 208 HLHQKGIIYRDLKPENIMLNHQ 229
>Hs14196445 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 476
Score = 55.8 bits (133), Expect = 3e-07
Identities = 62/264 (23%), Positives = 111/264 (41%), Gaps = 51/264 (19%)
Query: 646 KNPIVDFKKTNDLYCIRRELGEGGYATVYLAESS-TGQLSALKVEKPASVW-------EF 697
K + +KT + LG G ++ V+L + TG+L ALK K + + E
Sbjct: 13 KKQTTNIRKT---FIFMEVLGSGAFSEVFLVKQRLTGKLFALKCIKKSPAFRDSSLENEI 69
Query: 698 YILKQIERRVPDEAILKSIINVSALHCFQDESYLVLNYANQGTILDLVNWERERNGGALD 757
+LK+I+ ++I+ + ++ YLV+ + G + D + ER G
Sbjct: 70 AVLKKIKH--------ENIVTLEDIYESTTHYYLVMQLVSGGELFDRI---LER--GVYT 116
Query: 758 ECLCMFITVELMRVLECIHDVGIIHGDIKPDNCMIRFQKVSHLGKYFANGENGWNRKGIY 817
E + +++ ++ +H+ GI+H D+KP+N + Y EN I
Sbjct: 117 EKDASLVIQQVLSAVKYLHENGIVHRDLKPENLL-----------YLTPEEN----SKIM 161
Query: 818 LIDFGRSFDLSLFPLGTKFRSNWKTDQQDCPEMREQRPWSYEADYYGLAGVIFCMLFGH- 876
+ DFG LS + T PE+ Q+P+S D + + + + +L G+
Sbjct: 162 ITDFG----LSKMEQNGIMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVITYILLCGYP 217
Query: 877 --YIET-----VKVASNRYQLKSP 893
Y ET K+ Y+ +SP
Sbjct: 218 PFYEETESKLFEKIKEGYYEFESP 241
>At2g45490 [D] KOG0580 Serine/threonine protein kinase
Length = 288
Score = 55.8 bits (133), Expect = 3e-07
Identities = 57/219 (26%), Positives = 96/219 (43%), Gaps = 31/219 (14%)
Query: 661 IRRELGEGGYATVYLA-ESSTGQLSALKVEKPASVWEFYILKQIERRVPDEAILKSIINV 719
I R LG+G + VYLA E+ + + ALKV + ++ I Q+ R + + L+ +
Sbjct: 24 IGRPLGKGKFGRVYLAREAKSKYIVALKVIFKEQIEKYKIHHQLRREMEIQTSLRHPNIL 83
Query: 720 SALHCFQDES--YLVLNYANQGTILDLVNWERERNGGALDECLCMFITVELMRVLECIHD 777
F D +L+L YA+ G + ++ ++NG ++ +I L + L H
Sbjct: 84 RLFGWFHDNERIFLILEYAHGGELYGVL----KQNGHLTEQQAATYIA-SLSQALAYCHG 138
Query: 778 VGIIHGDIKPDNCMIRFQKVSHLGKYFANGENGWNRKGIYLIDFGRSFDLSLFPLGTKFR 837
+IH DIKP+N ++ H G+ + + DFG S S K +
Sbjct: 139 KCVIHRDIKPENLLL-----DHEGR-------------LKIADFGWSVQSS-----NKRK 175
Query: 838 SNWKTDQQDCPEMREQRPWSYEADYYGLAGVIFCMLFGH 876
+ T PEM E R Y D + L + + L+G+
Sbjct: 176 TMCGTLDYLAPEMVENRDHDYAVDNWTLGILCYEFLYGN 214
>YNR047w [R] KOG0610 Putative serine/threonine protein kinase
Length = 893
Score = 55.5 bits (132), Expect = 4e-07
Identities = 89/379 (23%), Positives = 141/379 (36%), Gaps = 94/379 (24%)
Query: 425 DGLTGH-SDGKSKSPTVTMFSKDAMNEVYSMFNQSYHDMKNYSDHDDTTSGKFTMYENFQ 483
D L G S G SKSPT+T + F+ Y + N HD+ Q
Sbjct: 334 DTLNGSPSRGSSKSPTITQ----TFPSIIVGFDNEYEEDNNNDKHDEKEE---------Q 380
Query: 484 EDLTGKNSEDLTEVKQPMESKNLSASTSANATPSRDQKQETTTPTFKSKLQDYMTPIQER 543
+ T + +L+ KQ + T P K L+ +
Sbjct: 381 QTTTDNKTRNLSPTKQ---------------------NGKATHPRIKIPLR------RAA 413
Query: 544 TEPNFKTLLSQDDDITGESRRKSTNSVNTAESSPFLTQPQRLLDPSPSHQIVENPXXXXX 603
+EPN L S T S RK++ S N + P + P P+ + P
Sbjct: 414 SEPNGLQLASATSP-TSSSARKTSGSSNINDKIPGQSVPP------PNSFFPQEPS---- 462
Query: 604 XXXXXXXXDPALASYPTYYEYSQQLKMSSLLKRIQKVSKNMNKNPIVDFKKTNDLYCIRR 663
P ++ +P S++L+ S + Q + F+K R
Sbjct: 463 ---------PKISDFPEPRR-SRRLRTKSFSNKFQDIMVGPQS-----FEKI-------R 500
Query: 664 ELGEGGYATVYLA-ESSTGQLSALKVEKPASVWEFYILKQIERRVPDEAILKSIIN---V 719
LG+G V+L E T ++ ALKV S E +I+R + ++ IL + + V
Sbjct: 501 LLGQGDVGKVFLVREKKTNRVYALKV---LSKDEMIKRNKIKRVLTEQEILATSNHPFIV 557
Query: 720 SALHCFQDESYLVL--NYANQGTILDLVNWERERNGGALDECLC----MFITVELMRVLE 773
+ H FQ E YL L Y G + + + C+C F E+ LE
Sbjct: 558 TLYHSFQSEDYLYLCMEYCMGGEFFRALQTRKTK-------CICEDDARFYASEVTAALE 610
Query: 774 CIHDVGIIHGDIKPDNCMI 792
+H +G I+ D+KP+N ++
Sbjct: 611 YLHLLGFIYRDLKPENILL 629
>SPAC24B11.11c [R] KOG0605 NDR and related serine/threonine kinases
Length = 607
Score = 55.1 bits (131), Expect = 5e-07
Identities = 36/134 (26%), Positives = 70/134 (51%), Gaps = 12/134 (8%)
Query: 664 ELGEGGYATVYLAES-STGQLSALKVEKPASVWEFYILKQI--ERRVPDEAILKSIINVS 720
++G+GGY +V+LA T ++ ALK+ + + + ++ + ER + A + ++ +
Sbjct: 213 QVGQGGYGSVWLARKRDTKEIVALKIMNKSVLHKMDEIRHVLTERDILTTANSEWLVRL- 271
Query: 721 ALHCFQDES--YLVLNYANQGTILDLVNWERERNGGALDECLCMFITVELMRVLECIHDV 778
L+ FQD S YL + + G L++ N G L + F E+ ++ +H +
Sbjct: 272 -LYAFQDTSNIYLAMEFVPGGDFRTLLS-----NSGVLRDHHAKFYATEMFLAIDALHQL 325
Query: 779 GIIHGDIKPDNCMI 792
G IH D+KP+N ++
Sbjct: 326 GYIHRDLKPENFLV 339
>At1g01140 [T] KOG0583 Serine/threonine protein kinase
Length = 447
Score = 55.1 bits (131), Expect = 5e-07
Identities = 34/137 (24%), Positives = 71/137 (51%), Gaps = 8/137 (5%)
Query: 659 YCIRRELGEGGYATVYLAESS-TGQLSALKVEKPASVWEFYILKQIERRVPDEAILK--S 715
Y + R LGEG +A V A+++ TG +A+K+ V+ +++Q++R + ++K +
Sbjct: 19 YEMGRTLGEGSFAKVKYAKNTVTGDQAAIKILDREKVFRHKMVEQLKREISTMKLIKHPN 78
Query: 716 IINVSALHCFQDESYLVLNYANQGTILDLVNWERERNGGALDECLCMFITVELMRVLECI 775
++ + + + + Y+VL N G + D + + G L E +L+ ++
Sbjct: 79 VVEIIEVMASKTKIYIVLELVNGGELFDKIAQQ-----GRLKEDEARRYFQQLINAVDYC 133
Query: 776 HDVGIIHGDIKPDNCMI 792
H G+ H D+KP+N ++
Sbjct: 134 HSRGVYHRDLKPENLIL 150
>YKL166c [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 398
Score = 54.3 bits (129), Expect = 9e-07
Identities = 61/246 (24%), Positives = 106/246 (42%), Gaps = 50/246 (20%)
Query: 646 KNPIVDFKKTNDLYC-----IRRELGEGGYATVYLAESS-TGQLSALKVEKPASVWEFYI 699
K P++ ++ T+ Y I R LG G + V+L S+ G+ ALK K ++ +
Sbjct: 70 KKPMLQYRDTSGKYSLSDFQILRTLGTGSFGRVHLIRSNHNGRFYALKTLKKHTIVK--- 126
Query: 700 LKQIERRVPDEAILKSIIN----VSALHCFQDES--YLVLNYANQGTILDLVNWERERNG 753
LKQ+E DE + SI++ + FQD ++V++Y G + L+ R
Sbjct: 127 LKQVEH-TNDERRMLSIVSHPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLL-----RKS 180
Query: 754 GALDECLCMFITVELMRVLECIHDVGIIHGDIKPDNCMIRFQKVSHLGKYFANGENGWNR 813
+ F E+ LE +H II+ D+KP+N ++ +NG
Sbjct: 181 QRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILL--------------DKNGH-- 224
Query: 814 KGIYLIDFGRSF---DLSLFPLGTKFRSNWKTDQQDCPEMREQRPWSYEADYYGLAGVIF 870
I + DFG + D++ GT PE+ +P++ D++ +I+
Sbjct: 225 --IKITDFGFAKYVPDVTYTLCGTP--------DYIAPEVVSTKPYNKSVDWWSFGVLIY 274
Query: 871 CMLFGH 876
ML G+
Sbjct: 275 EMLAGY 280
>SPCC417.06c [R] KOG0605 NDR and related serine/threonine kinases
Length = 624
Score = 54.3 bits (129), Expect = 9e-07
Identities = 37/132 (28%), Positives = 65/132 (49%), Gaps = 8/132 (6%)
Query: 664 ELGEGGYATVYLAES-STGQLSALKVEKPASVWEFYILKQIERRVPDEAILKSIINVSAL 722
+LG+GGY +V+LA+ +T +L A+K+ K +++ + +K I S V
Sbjct: 167 KLGQGGYGSVWLAKKRNTHELLAMKMMKKSTLQQLNEVKHILNERDILTNTNSEWLVKLY 226
Query: 723 HCFQDES--YLVLNYANQGTILDLVNWERERNGGALDECLCMFITVELMRVLECIHDVGI 780
+ FQD+ YL + Y G + + G L E F E++ + +H +G
Sbjct: 227 YAFQDKEKVYLAMEYVPGGDFRTFLTTK-----GLLHENQTRFYLAEMVAAISAVHKLGY 281
Query: 781 IHGDIKPDNCMI 792
+H D+KP+N +I
Sbjct: 282 MHRDLKPENFLI 293
>SPCC320.12c [D] KOG0580 Serine/threonine protein kinase
Length = 384
Score = 54.3 bits (129), Expect = 9e-07
Identities = 42/168 (25%), Positives = 82/168 (48%), Gaps = 9/168 (5%)
Query: 629 KMSSLLKRIQKVSKNMNKNPIVDFKKTN-DLYCIRRELGEGGYATVYLA-ESSTGQLSAL 686
K +S L++I++ + + +++ + ++ I + LG+G + VYLA E TG + AL
Sbjct: 87 KFNSSLRKIEEPIAGVPSSAGPQWREFHIGMFEIGKPLGKGKFGRVYLAKEKKTGFIVAL 146
Query: 687 KVEKPASVWEFYILKQIERRVPDEAILKSIINVSALHCFQDES--YLVLNYANQGTILDL 744
K + + + I KQ+ R + ++ L+ + F DE YL+L +A +G +
Sbjct: 147 KTLHKSELVQSKIEKQVRREIEIQSNLRHKNILRLYGHFHDEKRIYLILEFAGRGEL--- 203
Query: 745 VNWERERNGGALDECLCMFITVELMRVLECIHDVGIIHGDIKPDNCMI 792
++ R E + ++ L +H +IH DIKP+N ++
Sbjct: 204 --YQHLRRAKRFSEEVASKYIFQMANALSYLHKKHVIHRDIKPENILL 249
>Hs4507273 [D] KOG0580 Serine/threonine protein kinase
Length = 275
Score = 54.3 bits (129), Expect = 9e-07
Identities = 71/277 (25%), Positives = 116/277 (41%), Gaps = 41/277 (14%)
Query: 655 TNDLYCIRRELGEGGYATVYLAESSTGQ-LSALKVEKPASVWEFYILKQIERRVPDEAIL 713
T D + I R LG+G + VYLA + ALKV + + + + Q+ R + +A L
Sbjct: 5 TVDDFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHL 64
Query: 714 KSIINVSALHCFQDES--YLVLNYANQGTILDLVNWERERNGGALDECLCMFITVELMRV 771
+ + + F D YL+L YA +G + ++ + LDE I E+
Sbjct: 65 QHPNILRLYNYFHDARRVYLILEYAPRGEL-----YKELQKSEKLDEQRTATIIEEVADA 119
Query: 772 LECIHDVGIIHGDIKPDNCMIRFQKVSHLGKYFANGENGWNRKGIYLIDFGRSFDLSLFP 831
L HD +IH DIKP+N ++ F R + + DFG S L
Sbjct: 120 LTYCHDKKVIHRDIKPENLLLGF------------------RGEVKIADFGWSVHTPL-- 159
Query: 832 LGTKFRSNWKTDQQDCPEMREQRPWSYEADYYGLAGVIFCMLFGHYIETVKVASNRYQLK 891
+ ++ T PEM E R + + D + + + + +L G+ S Y
Sbjct: 160 --PERKTMCGTLDYLPPEMIEGRTYDEKVDLWCIGVLCYELLVGYPPFESASHSETY--- 214
Query: 892 SPLKRYWQQDIWNPLFDLLINSGAHDSTLVSKLRHYR 928
+R + D+ F L + GA D L+S+L Y+
Sbjct: 215 ---RRILKVDV---RFPLSMPLGARD--LISRLLRYQ 243
>7295426 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 490
Score = 54.3 bits (129), Expect = 9e-07
Identities = 47/168 (27%), Positives = 84/168 (49%), Gaps = 19/168 (11%)
Query: 637 IQKVSKNMNKNPIVDFKKTNDLYCIRRELGEGGYATVYLAESSTGQLS----ALKVEKPA 692
IQ +N+N I K +L ++ LG+GGY V+ + G+ + A+KV K A
Sbjct: 58 IQLCEENVNPGKIKLGPKDFEL---KKVLGKGGYGKVFQVRKTAGRDANKYFAMKVLKKA 114
Query: 693 SVWEFYILKQIERRVPDEAILKSIIN---VSALHCFQDES--YLVLNYANQGTILDLVNW 747
S+ K + IL+++ + V ++ FQ + YL+L Y + G +
Sbjct: 115 SIVTNQ--KDTAHTRAERNILEAVKHPFIVELVYAFQTDGKLYLILEYLSGGELF----M 168
Query: 748 ERERNGGALDECLCMFITVELMRVLECIHDVGIIHGDIKPDNCMIRFQ 795
ER G L++ C +++ E++ L +H +GII+ D+KP+N ++ Q
Sbjct: 169 HLEREGIFLEDTTCFYLS-EIILALGHLHKLGIIYRDLKPENILLDAQ 215
>At5g45820 [T] KOG0583 Serine/threonine protein kinase
Length = 439
Score = 53.9 bits (128), Expect = 1e-06
Identities = 40/152 (26%), Positives = 75/152 (49%), Gaps = 13/152 (8%)
Query: 644 MNKNPIVDFKKTNDLYCIRRELGEGGYATVYLAES-STGQLSALKVEKPASVWEFYILKQ 702
M+KN IV +K Y + R LG+G +A VY A + TG+ A+KV V + ++ Q
Sbjct: 1 MDKNGIVLMRK----YELGRLLGQGTFAKVYHARNIKTGESVAIKVIDKQKVAKVGLIDQ 56
Query: 703 IERRVPDEAILKS--IINVSALHCFQDESYLVLNYANQGTILDLVNWERERNGGALDECL 760
I+R + +++ ++ + + + + Y + Y G + D V+ G L E +
Sbjct: 57 IKREISVMRLVRHPHVVFLHEVMASKTKIYFAMEYVKGGELFDKVS------KGKLKENI 110
Query: 761 CMFITVELMRVLECIHDVGIIHGDIKPDNCMI 792
+L+ ++ H G+ H D+KP+N ++
Sbjct: 111 ARKYFQQLIGAIDYCHSRGVYHRDLKPENLLL 142
>At2g26980 [T] KOG0583 Serine/threonine protein kinase
Length = 441
Score = 53.9 bits (128), Expect = 1e-06
Identities = 34/137 (24%), Positives = 68/137 (48%), Gaps = 8/137 (5%)
Query: 659 YCIRRELGEGGYATVYLAESS-TGQLSALKVEKPASVWEFYILKQIERRVPDEAILK--S 715
Y + R +GEG +A V A +S TG+ ALK+ V + + +QI R + ++K +
Sbjct: 14 YEVGRTIGEGTFAKVKFARNSETGEPVALKILDKEKVLKHKMAEQIRREIATMKLIKHPN 73
Query: 716 IINVSALHCFQDESYLVLNYANQGTILDLVNWERERNGGALDECLCMFITVELMRVLECI 775
++ + + + + +++L Y G + D + N G + E +L+ ++
Sbjct: 74 VVQLYEVMASKTKIFIILEYVTGGELFDKIV-----NDGRMKEDEARRYFQQLIHAVDYC 128
Query: 776 HDVGIIHGDIKPDNCMI 792
H G+ H D+KP+N ++
Sbjct: 129 HSRGVYHRDLKPENLLL 145
>YPL203w [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 380
Score = 53.5 bits (127), Expect = 2e-06
Identities = 65/258 (25%), Positives = 110/258 (42%), Gaps = 49/258 (18%)
Query: 626 QQLKMSSLLKRIQKVSKNMNKNPIVDFKKTNDLYCIRRELGEGGYATVYLAES-STGQLS 684
QQL S L QK + K + DF+ I R LG G + V+L S G+
Sbjct: 47 QQLLTSQLP---QKSLVSKGKYTLHDFQ-------IMRTLGTGSFGRVHLVRSVHNGRYY 96
Query: 685 ALKVEKPASVWEFYILKQIERRVPDEAILKSIINVSALHC---FQDES--YLVLNYANQG 739
A+KV K V + +KQ+E + +LK + + + FQD ++V++Y G
Sbjct: 97 AIKVLKKQQVVK---MKQVEHTNDERRMLKLVEHPFLIRMWGTFQDARNIFMVMDYIEGG 153
Query: 740 TILDLVNWERERNGGALDECLCMFITVELMRVLECIHDVGIIHGDIKPDNCMIRFQKVSH 799
+ L+ R + F E++ LE +H II+ D+KP+N ++
Sbjct: 154 ELFSLL-----RKSQRFPNPVAKFYAAEVILALEYLHAHNIIYRDLKPENILL------- 201
Query: 800 LGKYFANGENGWNRKG-IYLIDFGRSFDLSLFPLGTKFRSNWKTDQQDCPEMREQRPWSY 858
+R G I + DFG + ++ T + T PE+ +P++
Sbjct: 202 ------------DRNGHIKITDFGFAKEVQ-----TVTWTLCGTPDYIAPEVITTKPYNK 244
Query: 859 EADYYGLAGVIFCMLFGH 876
D++ L +I+ ML G+
Sbjct: 245 SVDWWSLGVLIYEMLAGY 262
>SPCC24B10.07 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 569
Score = 53.5 bits (127), Expect = 2e-06
Identities = 41/165 (24%), Positives = 75/165 (44%), Gaps = 19/165 (11%)
Query: 636 RIQKVSKNMNKNPIVDFKKTNDLYCIRRELGEGGYATVY-LAESSTGQLSALKVEKPASV 694
R+Q + K P+ T D + + + +G+G + V + + T ++ ALK K A +
Sbjct: 212 RVQMLYKPNQSTPL-----TIDAFELLKVVGKGSFGKVMQVRKRDTSRIYALKTMKKAHI 266
Query: 695 WEFYILKQIERRVPDEAILKSIIN---VSALHCFQDES--YLVLNYANQGTILDLVNWER 749
+++ + + +L + N V FQ YLVL + N G + + E
Sbjct: 267 VS---RSEVDHTLAERTVLAQVNNPFIVPLKFSFQSPGKLYLVLAFVNGGELFHHLQRE- 322
Query: 750 ERNGGALDECLCMFITVELMRVLECIHDVGIIHGDIKPDNCMIRF 794
G D F EL+ LEC+H+ +I+ D+KP+N ++ +
Sbjct: 323 ----GCFDTYRAKFYIAELLVALECLHEFNVIYRDLKPENILLDY 363
>Hs14249562 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 878
Score = 53.1 bits (126), Expect = 2e-06
Identities = 40/136 (29%), Positives = 65/136 (47%), Gaps = 8/136 (5%)
Query: 659 YCIRRELGEGGYATVYLAESSTGQLSALKVEKPASVWEFYILKQIERRVPDEAILKSIIN 718
+ I + + G + VYL + G+L A+KV K A + + Q++ A+ KS
Sbjct: 35 FSIVKPISRGAFGKVYLGQKG-GKLYAVKVVKKADMINKNMTHQVQAERDALALSKSPFI 93
Query: 719 VSALHCFQDES--YLVLNYANQGTILDLVNWERERNGGALDECLCMFITVELMRVLECIH 776
V + Q + YLV+ Y G + L++ G DE + + E+ L+ +H
Sbjct: 94 VHLYYSLQSANNVYLVMEYLIGGDVKSLLHIY-----GYFDEEMAVKYISEVALALDYLH 148
Query: 777 DVGIIHGDIKPDNCMI 792
GIIH D+KPDN +I
Sbjct: 149 RHGIIHRDLKPDNMLI 164
>At1g69220 [T] KOG0576 Mitogen-activated protein kinase kinase kinase kinase
(MAP4K) germinal center kinase family
Length = 836
Score = 53.1 bits (126), Expect = 2e-06
Identities = 43/173 (24%), Positives = 79/173 (44%), Gaps = 8/173 (4%)
Query: 635 KRIQKVSKNMNKNPIVDFKKTND---LYCIRRELGEGGYATVYLAES-STGQLSALKVEK 690
+++Q+ + M+ + D D Y ELG+G Y +VY A T ++ A+KV
Sbjct: 222 RKMQQQNSKMSTTSLPDSITREDPTTKYEFLNELGKGSYGSVYKARDLKTSEIVAVKVIS 281
Query: 691 PASVWEFYILKQIERRVPDEAILKSIINVSALHCFQDESYLVLNYANQGTILDLVNWERE 750
E Y + E + + +++ + +D ++V+ Y G++ DL+N E
Sbjct: 282 LTEGEEGYEEIRGEIEMLQQCNHPNVVRYLGSYQGEDYLWIVMEYCGGGSVADLMNVTEE 341
Query: 751 RNGGALDECLCMFITVELMRVLECIHDVGIIHGDIKPDNCMIRFQKVSHLGKY 803
AL+E +I E ++ L +H + +H DIK N ++ Q LG +
Sbjct: 342 ----ALEEYQIAYICREALKGLAYLHSIYKVHRDIKGGNILLTEQGEVKLGDF 390
>Hs4759178 [D] KOG0580 Serine/threonine protein kinase
Length = 344
Score = 52.8 bits (125), Expect = 3e-06
Identities = 48/159 (30%), Positives = 75/159 (46%), Gaps = 9/159 (5%)
Query: 638 QKVSKNMNKNP-IVDFKKTNDLYCIRRELGEGGYATVYLA-ESSTGQLSALKVEKPASVW 695
QKV +N + P I+ T D + I R LG+G + VYLA E + + ALKV + +
Sbjct: 55 QKVMENSSGTPDILTRHFTIDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIE 114
Query: 696 EFYILKQIERRVPDEAILKSIINVSALHCFQDES--YLVLNYANQGTILDLVNWERERNG 753
+ + Q+ R + +A L + + F D YL+L YA +G + ++ +
Sbjct: 115 KEGVEHQLRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAPRGEL-----YKELQKS 169
Query: 754 GALDECLCMFITVELMRVLECIHDVGIIHGDIKPDNCMI 792
DE I EL L H +IH DIKP+N ++
Sbjct: 170 CTFDEQRTATIMEELADALMYCHGKKVIHRDIKPENLLL 208
>CE25046 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 348
Score = 52.8 bits (125), Expect = 3e-06
Identities = 62/259 (23%), Positives = 113/259 (42%), Gaps = 51/259 (19%)
Query: 659 YCIRRELGEGGYATVYLAESST--GQLSALK-VEKPASVWEFYILKQIERRVPDEA-ILK 714
Y R LG G ++ V+LAES + GQ+ A+K ++K A LK E + +E +L+
Sbjct: 22 YDFRDVLGTGAFSKVFLAESKSDAGQMYAVKCIDKKA-------LKGKEESLENEIKVLR 74
Query: 715 SIINVSALHCFQ--DES---YLVLNYANQGTILDLVNWERERNGGALDECLCMFITVELM 769
+ + + + F DE YLV+ G + D + + G+ E + +++
Sbjct: 75 KLRHNNIVQLFDTYDEKQFVYLVMELVTGGELFDRIVAK-----GSYTEQDASNLIRQVL 129
Query: 770 RVLECIHDVGIIHGDIKPDNCMIRFQKVSHLGKYFANGENGWNRKGIYLIDFGRSFDLSL 829
+ +HD G++H D+KP+N + Y+ E+ I + DFG S
Sbjct: 130 EAVGFMHDNGVVHRDLKPENLL-----------YYNQDED----SKIMISDFGLSKTEDS 174
Query: 830 FPLGTKFRSNWKTDQQDCPEMREQRPWSYEADYYGLAGVIFCMLFGH---YIET-----V 881
+ T T PE+ +Q+P+ D + + + + +L G+ Y E+
Sbjct: 175 GVMATA----CGTPGYVAPEVLQQKPYGKAVDVWSIGVIAYILLCGYPPFYDESDANLFA 230
Query: 882 KVASNRYQLKSPLKRYWQQ 900
++ Y+ +P YW Q
Sbjct: 231 QIIKGEYEFDAP---YWDQ 246
>CE22877 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 632
Score = 52.8 bits (125), Expect = 3e-06
Identities = 52/215 (24%), Positives = 97/215 (44%), Gaps = 29/215 (13%)
Query: 665 LGEGGYATVY-LAESSTGQLSALKVEKPASVWEFYILKQIERRVPDEAILKSIINVSALH 723
LG+GG+A Y L STG+L A KV A + + Y ++ + V L+ V H
Sbjct: 42 LGKGGFAHCYELRNKSTGELFAGKVVPKALLIKQYQRDKMAQEVQIHRNLQHRNVVKLYH 101
Query: 724 CFQDES--YLVLNYANQGTILDLVNWERERNGGALDECLCMFITVELMRVLECIHDVGII 781
F+D+S Y+ L + ++++L + A+ E + T +++ + +H++ I+
Sbjct: 102 FFEDKSNVYITLELCPRRSLMEL-----HKRRKAVTEPEARYFTYQIVEGVLYLHNLKIV 156
Query: 782 HGDIKPDNCMIRFQKVSHLGKYFANGENGWNRKGIYLIDFGRSFDLSLFPLGTKFRSNWK 841
H D+K LG F N E + + DFG + + + ++
Sbjct: 157 HRDLK-------------LGNLFLNDE-----LQVKIGDFGLA---TTCDNDERKKTLCG 195
Query: 842 TDQQDCPEMREQRPWSYEADYYGLAGVIFCMLFGH 876
T PE+ + S+E D + + +++ +LFGH
Sbjct: 196 TPNYIAPEVLNKIGHSFEVDLWAIGCILYILLFGH 230
>Hs7657526 [T] KOG0603 Ribosomal protein S6 kinase
Length = 745
Score = 52.4 bits (124), Expect = 3e-06
Identities = 56/216 (25%), Positives = 94/216 (42%), Gaps = 30/216 (13%)
Query: 665 LGEGGYATVYLAESSTG----QLSALKVEKPASVW-EFYILKQIERRVPDEAILKSIINV 719
LG+G + V+L TG QL A+KV K AS+ + ++ER + E I+ +
Sbjct: 79 LGQGSFGKVFLVRKKTGPDAGQLYAMKVLKKASLKVRDRVRTKMERDILVEVNHPFIVKL 138
Query: 720 SALHCFQDESYLVLNYANQGTILDLVNWERERNGGALDECLCMFITVELMRVLECIHDVG 779
+ + YL+L++ G + ++ E E F EL L+ +H +G
Sbjct: 139 HYAFQTEGKLYLILDFLRGGDVFTRLSKEV-----LFTEEDVKFYLAELALALDHLHQLG 193
Query: 780 IIHGDIKPDNCMIRFQKVSHLGKYFANGENGWNRKGIYLIDFGRSFDLSLFPLGTKFRSN 839
I++ D+KP+N ++ ++ H I L DFG S + K S
Sbjct: 194 IVYRDLKPENILL--DEIGH----------------IKLTDFGLSKE--SVDQEKKAYSF 233
Query: 840 WKTDQQDCPEMREQRPWSYEADYYGLAGVIFCMLFG 875
T + PE+ +R S AD++ ++F ML G
Sbjct: 234 CGTVEYMAPEVVNRRGHSQSADWWSYGVLMFEMLTG 269
>ECU01g0630 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 488
Score = 52.4 bits (124), Expect = 3e-06
Identities = 54/241 (22%), Positives = 104/241 (42%), Gaps = 29/241 (12%)
Query: 639 KVSKNMNKNPIVDFKKTNDLYCIRRELGEGGYATVYLAESSTGQLSALKVEKPASVWEFY 698
KV M ++ + + Y +++ LG G YA YLAE +G+ A+KV + +
Sbjct: 20 KVELYMEIGTVITDLEYHTKYMLKKLLGRGAYAQCYLAEIESGEQYAMKVVRLKDIKSRK 79
Query: 699 ILKQIERRVPDEAILKSIINVSALHCFQDESY--LVLNYANQGTILDLVNWERERNGGAL 756
+ +++E + + L + V F+ Y +VL +G + L+ +RNG
Sbjct: 80 VHEKLESEIAIHSKLDNPNVVKMYRSFRSSEYVFMVLELCERGALDALL----KRNGKLK 135
Query: 757 DECLCMFITVELMRVLECIHDVGIIHGDIKPDNCMIRFQKVSHLGKYFANGENGWNRKGI 816
+ + F+ + ++ + V ++H D+K LG F + ++ +
Sbjct: 136 ERHVARFVKQTVEGLIYLHNSVSVVHRDLK-------------LGNLFLD-----SKFNV 177
Query: 817 YLIDFGRSFDLSLFPLGTKFRSNWKTDQQDCPEM--REQRPWSYEADYYGLAGVIFCMLF 874
+ DFG S ++ G K + T PE+ + S+EAD + L +I+ +L
Sbjct: 178 KIGDFGLS---AVIKDGEKKVTMCGTPNYIAPEVLFGKASGHSFEADIWSLGVIIYTLLV 234
Query: 875 G 875
G
Sbjct: 235 G 235
>At3g46140 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 376
Score = 52.4 bits (124), Expect = 3e-06
Identities = 40/142 (28%), Positives = 62/142 (43%), Gaps = 24/142 (16%)
Query: 665 LGEGGYATVYLAESSTGQLSALKVEKPASVWEFYILKQIERRVPDEAILKSIINVSALHC 724
LG G Y +VYLA S + K A + + + +E IL + + + C
Sbjct: 102 LGRGSYGSVYLATSKKAKTKTTMAIKSAEI------SRASSLMDEERILTRLSSPFIVRC 155
Query: 725 FQDE-------------SY-LVLNYANQGTILDLVNWERERNGGALDECLCMFITVELMR 770
+ E +Y L+L Y + ++ DLVN N G L E + +++
Sbjct: 156 YGHEIAREETLFGGERTNYNLILEYCSGKSLFDLVN----DNLGGLSEKDVKLLARDILY 211
Query: 771 VLECIHDVGIIHGDIKPDNCMI 792
L+CIH IIH DIKP+N +
Sbjct: 212 GLDCIHRANIIHCDIKPENIFL 233
>At3g10660 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 646
Score = 52.4 bits (124), Expect = 3e-06
Identities = 79/381 (20%), Positives = 146/381 (37%), Gaps = 36/381 (9%)
Query: 503 SKNLSASTSANATPSRDQKQETTTPTFKSKLQDYMTPIQERTEPNFKTLLSQDDDITGES 562
++ S+S+ N S++ E T ++K + +T +T P +T L D +I E
Sbjct: 30 AEQASSSSHGNGQVSKEAASEPATDQVQNKPPEPITMPSSKTNP--ETKLKPDLEIQPEE 87
Query: 563 RRKSTNSVNTAESSPFLTQPQRLLDPSPSHQIVENPXXXXXXXXXXXXXDPALASYPTYY 622
+++ + T + Q + ++V P P T
Sbjct: 88 KKEKVLAEETKQKVVPEESKQEVPPEESKREVVVQPESAKPETKSESK--PETTKPETTS 145
Query: 623 EYSQQLKMSSLL-KRIQKVSKNMNKNPIVDFKKTN---DLYCIRRELGEGGYATVYLA-E 677
E + K K +++VS + V +KT + Y + R+LG+G + T +L E
Sbjct: 146 ETKPETKAEPQKPKHMRRVSSAGLRTESVLQRKTENFKEFYSLGRKLGQGQFGTTFLCLE 205
Query: 678 SSTGQLSALKVEKPASVWEFYILKQIERRVPDEAILKSIINVSALH-CFQD--ESYLVLN 734
TG A K + ++ + R + L NV ++ ++D +LV+
Sbjct: 206 KGTGNEYACKSISKRKLLTDEDVEDVRREIQIMHHLAGHPNVISIKGAYEDVVAVHLVME 265
Query: 735 YANQGTILDLVNWERERNGGALDECLCMFITVELMRVLECIHDVGIIHGDIKPDNCMIRF 794
+ G + D R G E + ++ VLE H +G++H D+KP+N +
Sbjct: 266 LCSGGELFD-----RIIQRGHYTERKAAELARTIVGVLEACHSLGVMHRDLKPENFLFVS 320
Query: 795 QKVSHLGKYFANGENGWNRKGIYLIDFGRSFDLSLFPLGTKFRSNWKTDQQDCPEMREQR 854
++ L K IDFG S F F + PE+ +R
Sbjct: 321 REEDSLLK---------------TIDFGLSM---FFKPDEVFTDVVGSPYYVAPEVLRKR 362
Query: 855 PWSYEADYYGLAGVIFCMLFG 875
+ E+D + +++ +L G
Sbjct: 363 -YGPESDVWSAGVIVYILLSG 382
>7300437 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 866
Score = 52.4 bits (124), Expect = 3e-06
Identities = 47/174 (27%), Positives = 80/174 (45%), Gaps = 18/174 (10%)
Query: 625 SQQL--KMSSLLKRIQKVSKNMNKNPIVDFKKTNDLYCIRRELGEGGYATVYLA--ESST 680
S+QL K++ L + + S+N I DF I + + G + V+L + +
Sbjct: 28 SEQLLDKINILTTKPENHSQNAKLPTIKDF-------VIIKPISRGAFGKVFLGYKNNDS 80
Query: 681 GQLSALKVEKPASVWEFYILKQIERRVPDEAILKSIINVSALHCFQDESY--LVLNYANQ 738
+L A+KV + + + ++ Q+ A+ +S VS + Q SY LV+ Y
Sbjct: 81 KRLFAIKVMRKSEMINKNMVSQVITERNALALSRSQFCVSLFYSLQSLSYVYLVMEYMVG 140
Query: 739 GTILDLVNWERERNGGALDECLCMFITVELMRVLECIHDVGIIHGDIKPDNCMI 792
G + L+ G DE F E++ L+ +H GI+H DIKPDN ++
Sbjct: 141 GDLKSLLAMF-----GYFDEPTARFYVAEMVMALQYLHQHGIVHRDIKPDNMLL 189
>Hs20428779_1 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 357
Score = 52.4 bits (124), Expect = 3e-06
Identities = 52/192 (27%), Positives = 82/192 (42%), Gaps = 36/192 (18%)
Query: 657 DLYCIRRELGEGGYATVY-LAESSTGQLSALKVEKPASVWEFYILKQIERRVPDEAILKS 715
D + I +G+G Y VY + G L+A+K+ P S + ++IE L +
Sbjct: 25 DTWEIIETIGKGTYGKVYKVTNKRDGSLAAVKILDPVSDMD----EEIEAEYNILQFLPN 80
Query: 716 IINV--------SALHCFQDESYLVLNYANQGTILDLVNWERERNGGALDECLCMFITVE 767
NV A HC + +LVL N G++ +LV R G LDE + +I
Sbjct: 81 HPNVVKFYGMFYKADHCVGGQLWLVLELCNGGSVTELVKGLL-RCGQRLDEAMISYILYG 139
Query: 768 LMRVLECIHDVGIIHGDIKPDNCMIRFQKVSHLGKYFANGENGWNRKGIYLIDFGRSFDL 827
+ L+ +H+ IIH D+K +N ++ G+ L+DFG S L
Sbjct: 140 ALLGLQHLHNNRIIHRDVKGNNILLT------------------TEGGVKLVDFGVSAQL 181
Query: 828 SLFPLGTKFRSN 839
+ T+ R N
Sbjct: 182 T----STRLRRN 189
>Hs20070247_2 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 378
Score = 52.4 bits (124), Expect = 3e-06
Identities = 60/250 (24%), Positives = 113/250 (45%), Gaps = 39/250 (15%)
Query: 635 KRIQKVSKNMNKNPIVDFKKTNDLYCIRRELGEGGYATVYLAESST-GQLSALKVEKPAS 693
+++ S+N+N P + + + +G+G + V LA+ G++ A+KV +
Sbjct: 20 QKLHSTSQNINLGPSGNPHAKPTDFDFLKVIGKGSFGKVLLAKRKLDGKVYAVKVLQKKI 79
Query: 694 VWEFYILKQI--ERRVPDEAILKSIIN---VSALHCFQ--DESYLVLNYANQGTILDLVN 746
V K I ER V +LK++ + V + FQ ++ Y VL++ N G + +
Sbjct: 80 VLNRKEQKHIMAERNV----LLKNVKHPFLVGLHYSFQTTEKLYFVLDFVNGGELF--FH 133
Query: 747 WERERNGGALDECLCMFITVELMRVLECIHDVGIIHGDIKPDNCMIRFQKVSHLGKYFAN 806
+RER+ E F E+ L +H + I++ D+KP+N ++ V H
Sbjct: 134 LQRERS---FPEHRARFYAAEIASALGYLHSIKIVYRDLKPENILV--DSVGH------- 181
Query: 807 GENGWNRKGIYLIDFGRSFD-LSLFPLGTKFRSNWKTDQQDCPEMREQRPWSYEADYYGL 865
+ L DFG + +++ T F T + PE+ ++P+ D++ L
Sbjct: 182 ---------VVLTDFGLCKEGIAISDTTTTFCG---TPEYLAPEVIRKQPYDNTVDWWCL 229
Query: 866 AGVIFCMLFG 875
V++ ML+G
Sbjct: 230 GAVLYEMLYG 239
>YGR092w [R] KOG0605 NDR and related serine/threonine kinases
Length = 572
Score = 52.0 bits (123), Expect = 4e-06
Identities = 49/176 (27%), Positives = 79/176 (44%), Gaps = 20/176 (11%)
Query: 625 SQQLKM----SSLLKRIQKVSKNMNKNPIVDFKKTNDLYCIRRELGEGGYATVYLA-ESS 679
S Q+K+ SS L+R +V + P K D I ++G+GGY VYLA +
Sbjct: 145 SDQIKLNEEWSSYLQREHQVLRKRRLKP-----KNRDFEMIT-QVGQGGYGQVYLARKKD 198
Query: 680 TGQLSALKVEKPASVWEFYILKQIERRVPDEAILKSIINVSALHCFQD--ESYLVLNYAN 737
T ++ ALK+ +++ K + +S V L+ FQD YL + +
Sbjct: 199 TKEVCALKILNKKLLFKLNETKHVLTERDILTTTRSEWLVKLLYAFQDLQSLYLAMEFVP 258
Query: 738 QGTILDL-VNWERERNGGALDECLCMFITVELMRVLECIHDVGIIHGDIKPDNCMI 792
G L +N ++G A F E+ + +HD+G H D+KP+N +I
Sbjct: 259 GGDFRTLLINTRCLKSGHA------RFYISEMFCAVNALHDLGYTHRDLKPENFLI 308
>Hs4885583 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1354
Score = 52.0 bits (123), Expect = 4e-06
Identities = 46/163 (28%), Positives = 79/163 (48%), Gaps = 23/163 (14%)
Query: 647 NPIVDFKKTNDLYCIRRELGEGGYATVYLAE-SSTGQLSALKVEKPASVWEFYILKQIER 705
N I D + + Y + + +G G + V L ST ++ A+K+ + +F ++K+ +
Sbjct: 64 NKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKL-----LSKFEMIKRSDS 118
Query: 706 RVPDE-----AILKSIINVSALHCFQDESYL--VLNYANQGTILDLV-NWERERNGGALD 757
E A S V + FQD+ YL V+ Y G +++L+ N++ +
Sbjct: 119 AFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYD-------VP 171
Query: 758 ECLCMFITVELMRVLECIHDVGIIHGDIKPDNCMIRFQKVSHL 800
E F T E++ L+ IH +G IH D+KPDN ++ K HL
Sbjct: 172 EKWARFYTAEVVLALDAIHSMGFIHRDVKPDNMLL--DKSGHL 212
>CE07599 [T] KOG0576 Mitogen-activated protein kinase kinase kinase kinase
(MAP4K) germinal center kinase family
Length = 829
Score = 52.0 bits (123), Expect = 4e-06
Identities = 42/143 (29%), Positives = 71/143 (49%), Gaps = 9/143 (6%)
Query: 653 KKTN--DLYCIRRELGEGGYATVYLAES-STGQLSALKVEKPASVWEFYILKQIERRVPD 709
K++N D Y + + +G G Y VY A + L+A+KV K + F +++Q E V
Sbjct: 7 KRSNPADDYELLQRVGSGTYGEVYKARDIRSDSLAAVKVVKLEAGDNFAVIQQ-EIMVIR 65
Query: 710 EAILKSIINVSALHCFQDESYLVLNYANQGTILDLVNWERERNGGALDECLCMFITVELM 769
E +II + +D ++V+ Y G++ D+ + G L E F+ E +
Sbjct: 66 ECSHPNIIAYFGSYIRRDRLWIVMEYCGGGSLQDIYHLT-----GPLSELQIAFVCRETL 120
Query: 770 RVLECIHDVGIIHGDIKPDNCMI 792
R L +H++G IH DIK N ++
Sbjct: 121 RGLNYLHNMGKIHRDIKGANILL 143
>YJL095w [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 1478
Score = 51.6 bits (122), Expect = 6e-06
Identities = 83/373 (22%), Positives = 153/373 (40%), Gaps = 58/373 (15%)
Query: 465 YSDHDDTTSGKFTMYENFQEDLTGKNSEDLTEVKQPMESKNLSASTSANATPSRDQKQET 524
+ ++D T + M+++ D +S+D+ + SK +A + N ++ +
Sbjct: 952 FEENDITFADAPPMFDSDDSDDDSSSSDDI------IWSKKKTAPETNNENKKDEKSDNS 1005
Query: 525 TTPT----FKSKLQDYMT------PIQERTEPNFKTLLSQ-------DDDITGESRRKST 567
+T + + S+ QD M P E N + + + I + KS
Sbjct: 1006 STHSDEIFYDSQTQDKMERKMTFRPSPEVVYQNLEKFFPRANLDKPITEGIASPTSPKSL 1065
Query: 568 NSV----NTAESSPFLTQPQRLLDPSPSHQIVENPXXXXXXXXXXXXXDPALASYPTY-Y 622
+S+ N A S + P R + P S++ +++ + T +
Sbjct: 1066 DSLLSPKNVASSRTEPSTPSRPVPPDSSYEFIQDGLNGKNKPLNQAKTPKRTKTIRTIAH 1125
Query: 623 EYSQQLKMSSLLKRIQK---------------VSKNMNKNPIVDFKKTNDLYCIRRELGE 667
E S K S LKR VS N KN ++K+ + +G+
Sbjct: 1126 EASLARKNSVKLKRQNTKMWGTRMVEVTENHMVSINKAKNSKGEYKEF--AWMKGEMIGK 1183
Query: 668 GGYATVYLAES-STGQLSALK-VEKPA-SVWEFYILKQIERRVPDEAILKSI--INVSAL 722
G + VYL + +TG++ A+K VE P S IL +E + + LK + +N+
Sbjct: 1184 GSFGAVYLCLNVTTGEMMAVKQVEVPKYSSQNEAILSTVEALRSEVSTLKDLDHLNIVQY 1243
Query: 723 HCFQDESY---LVLNYANQGTILDLVNWERERNGGALDECLCMFITVELMRVLECIHDVG 779
F++++ L L Y G++ L+ R G DE L +T ++++ L +H G
Sbjct: 1244 LGFENKNNIYSLFLEYVAGGSVGSLI-----RMYGRFDEPLIKHLTTQVLKGLAYLHSKG 1298
Query: 780 IIHGDIKPDNCMI 792
I+H D+K DN ++
Sbjct: 1299 ILHRDMKADNLLL 1311
>YCR091w [R] KOG0610 Putative serine/threonine protein kinase
Length = 720
Score = 51.6 bits (122), Expect = 6e-06
Identities = 57/219 (26%), Positives = 97/219 (44%), Gaps = 14/219 (6%)
Query: 663 RELGEGGYATVYLA-ESSTGQLSALKVEKPASVWEFYILKQIERRVPDEAILKSIIN--- 718
R LG+G VYL E T Q+ ALKV + E K+I+R + ++ IL + +
Sbjct: 328 RLLGQGDVGKVYLMRERDTNQIFALKV---LNKHEMIKRKKIKRVLTEQEILATSDHPFI 384
Query: 719 VSALHCFQDESYLVL--NYANQGTILDLVNWERERNGGALDECLCMFITVELMRVLECIH 776
V+ H FQ + YL L Y G + + R + E F E++ LE +H
Sbjct: 385 VTLYHSFQTKDYLYLCMEYCMGGEFFRAL---QTRKSKCIAEEDAKFYASEVVAALEYLH 441
Query: 777 DVGIIHGDIKPDNCMIRFQKVSHLGKYFANGENGWNRKGIYLIDFGRSFDLSLFPLGTKF 836
+G I+ D+KP+N ++ L + + + ++K + D + G +
Sbjct: 442 LLGFIYRDLKPENILLHQSGHVMLSDFDLSIQATGSKKP--TMKDSTYLDTKICSDGFRT 499
Query: 837 RSNWKTDQQDCPEMREQRPWSYEADYYGLAGVIFCMLFG 875
S T++ PE+ + D++ L +I+ MLFG
Sbjct: 500 NSFVGTEEYLAPEVIRGNGHTAAVDWWTLGILIYEMLFG 538
>CE18169 [T] KOG0603 Ribosomal protein S6 kinase
Length = 797
Score = 51.6 bits (122), Expect = 6e-06
Identities = 59/221 (26%), Positives = 97/221 (43%), Gaps = 38/221 (17%)
Query: 665 LGEGGYATVYLAES----STGQLSALKVEKPASVWEFYILKQIERRVPDEAILKSIIN-- 718
LG+G + V+L +G + A+KV K A++ ++ +R + IL I +
Sbjct: 110 LGQGSFGKVFLVRKVRGRDSGHVYAMKVLKKATLK----VRDRQRTKLERNILAHISHPF 165
Query: 719 -VSALHCFQDES--YLVLNYANQGTILDLVNWERERNGGALDECLCMFITVELMRVLECI 775
V + FQ E YL+L++ G + ++ E E F EL LE +
Sbjct: 166 IVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEV-----MFTEDDVKFYLAELTLALEHL 220
Query: 776 HDVGIIHGDIKPDNCMIRFQKVSHLGKYFANGENGWNRKGIYLIDFGRSFDLSLFPLGTK 835
H +GI++ D+KP+N ++ A+G I + DFG S + K
Sbjct: 221 HSLGIVYRDLKPENILLD-----------ADGH-------IKVTDFGLSKE--AIDSEKK 260
Query: 836 FRSNWKTDQQDCPEMREQRPWSYEADYYGLAGVIFCMLFGH 876
S T + PE+ +R S AD++ L ++F ML GH
Sbjct: 261 TYSFCGTVEYMAPEVINRRGHSMAADFWSLGVLMFEMLTGH 301
>CE13014 [T] KOG0603 Ribosomal protein S6 kinase
Length = 740
Score = 51.6 bits (122), Expect = 6e-06
Identities = 59/221 (26%), Positives = 97/221 (43%), Gaps = 38/221 (17%)
Query: 665 LGEGGYATVYLAES----STGQLSALKVEKPASVWEFYILKQIERRVPDEAILKSIIN-- 718
LG+G + V+L +G + A+KV K A++ ++ +R + IL I +
Sbjct: 53 LGQGSFGKVFLVRKVRGRDSGHVYAMKVLKKATLK----VRDRQRTKLERNILAHISHPF 108
Query: 719 -VSALHCFQDES--YLVLNYANQGTILDLVNWERERNGGALDECLCMFITVELMRVLECI 775
V + FQ E YL+L++ G + ++ E E F EL LE +
Sbjct: 109 IVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEV-----MFTEDDVKFYLAELTLALEHL 163
Query: 776 HDVGIIHGDIKPDNCMIRFQKVSHLGKYFANGENGWNRKGIYLIDFGRSFDLSLFPLGTK 835
H +GI++ D+KP+N ++ A+G I + DFG S + K
Sbjct: 164 HSLGIVYRDLKPENILLD-----------ADGH-------IKVTDFGLSKE--AIDSEKK 203
Query: 836 FRSNWKTDQQDCPEMREQRPWSYEADYYGLAGVIFCMLFGH 876
S T + PE+ +R S AD++ L ++F ML GH
Sbjct: 204 TYSFCGTVEYMAPEVINRRGHSMAADFWSLGVLMFEMLTGH 244
>CE03979 [T] KOG0614 cGMP-dependent protein kinase
Length = 581
Score = 51.6 bits (122), Expect = 6e-06
Identities = 60/274 (21%), Positives = 109/274 (38%), Gaps = 38/274 (13%)
Query: 665 LGEGGYATVYLAESSTGQLSALKVEKPASVWEFYILKQI--ERRVPDEAILKSIINVSAL 722
LG GG+ V L S++ + ALK+ A + E + ERR+ + I+ +
Sbjct: 280 LGMGGFGRVELVRSASSRTYALKIMNKAHIVETKQESHVVSERRILMQCDNDYIVRMYKT 339
Query: 723 HCFQDESYLVLNYANQGTILDLVNWERERNGGALDECLCMFITVELMRVLECIHDVGIIH 782
+ ++ Y+++ G I W R G D L F M LE +H I++
Sbjct: 340 YRDSEKIYMLMEPCLGGEI-----WTILRKKGRFDNDLTRFYCAGAMEALEYLHRKNIVY 394
Query: 783 GDIKPDNCMIRFQKVSHLGKYFANGENGWNRKGIYLIDFGRSFDLSLFPLGTKFRSNWKT 842
D+KP+N ++ NGW + L+DFG + L G + + T
Sbjct: 395 RDLKPENMLL--------------DRNGWPK----LVDFGFAKKLK---NGGRTWTFCGT 433
Query: 843 DQQDCPEMREQRPWSYEADYYGLAGVIFCMLF---GHYIETVKVASNRYQLKSPLKRYWQ 899
+ PE+ + D + L G+ C L + T + + LK K W
Sbjct: 434 AEYVAPEIVLNKGHDLSVDIWAL-GIFMCELLTGSPPFSSTDPMVTYNAILKGLEKWAWP 492
Query: 900 QDIWNPLFDLLINSGAHDSTL------VSKLRHY 927
+ + D++++ ++ T + ++RH+
Sbjct: 493 RFVTKEAIDMMLSLCKYEPTERLGFGDIGEIRHH 526
>7298652 [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 459
Score = 51.6 bits (122), Expect = 6e-06
Identities = 53/224 (23%), Positives = 93/224 (40%), Gaps = 30/224 (13%)
Query: 579 LTQPQRLLDPSPSHQIVENPXXXXXXXXXXXXXDPALASYPTYYEYSQQLKMSSLLKRIQ 638
LT P + D S + V N D S+PTY +
Sbjct: 91 LTNPVYIQDLSRNGTFVNNEKIGTNRMRILKNDDVISLSHPTYKAF-------------- 136
Query: 639 KVSKNMNKNPIVDF-KKTNDLYCIRRELGEGGYATVYLA-ESSTGQLSALKVEKP---AS 693
V K+++ N + ++ N Y + R+LG G Y V L ++ T Q A+K+ K +
Sbjct: 137 -VFKDLSPNESIGLPEEINKTYYVNRKLGSGAYGLVRLVYDTRTCQQFAMKIVKKNMLSG 195
Query: 694 VWEFYILKQIERRVPDEAILKSIIN--VSALHCFQDES---YLVLNYANQGTILDLVNWE 748
+R + + I+K++ + V +H D+ Y+VL + G +L+
Sbjct: 196 ARPSTNFSDPDRVLNEAKIMKNLSHPCVVRMHDIVDKPDSVYMVLEFMRGGDLLN----- 250
Query: 749 RERNGGALDECLCMFITVELMRVLECIHDVGIIHGDIKPDNCMI 792
R + L E + ++ ++ +HD GI H D+KPDN ++
Sbjct: 251 RIISNKLLSEDISKLYFYQMCHAVKYLHDRGITHRDLKPDNVLL 294
>YNR031c [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and related
serine/threonine protein kinases
Length = 1579
Score = 51.2 bits (121), Expect = 8e-06
Identities = 38/195 (19%), Positives = 92/195 (46%), Gaps = 25/195 (12%)
Query: 623 EYSQQLKMSSLLKRIQKVSKNMNKN-PIVDFKKTNDLYCI---------------RRELG 666
+ + + ++ S+++ +++ +N ++ ++D + Y + R +G
Sbjct: 1214 QVNSEFRVQSIMELEERIKRNPHQTGKVIDDSDKGNKYLVSLASSISNVSMRWQKRNFIG 1273
Query: 667 EGGYATVYLA-ESSTGQLSALK---VEKPASVWEFYILKQIERRVPDEAILKSIINVSAL 722
G + VY A + G++ A+K ++ S+ + + L + E V + +I++ +
Sbjct: 1274 GGTFGRVYSAVDLDNGEILAVKEINIQDSKSMQKIFPLIKEEMSVLEILNHPNIVSYYGV 1333
Query: 723 HCFQDESYLVLNYANQGTILDLVNWERERNGGALDECLCMFITVELMRVLECIHDVGIIH 782
+D+ + + Y G++ L+ +G DE + T++L+ L +H+ GI+H
Sbjct: 1334 EVHRDKVNIFMEYCEGGSLAALLE-----HGRIEDEMVTQVYTLQLLEGLAYLHESGIVH 1388
Query: 783 GDIKPDNCMIRFQKV 797
D+KP+N ++ F V
Sbjct: 1389 RDVKPENILLDFNGV 1403
>Hs9966875 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 357
Score = 51.2 bits (121), Expect = 8e-06
Identities = 72/283 (25%), Positives = 120/283 (41%), Gaps = 53/283 (18%)
Query: 646 KNPIVDFKKTNDLYCIRRELGEGGYATVYLAES-STGQLSALK-VEKPASVWEFYILKQI 703
K D KK ++ + LG G ++ V LAE +TG+L A+K + K A LK
Sbjct: 13 KKQAEDIKK---IFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKA-------LKGK 62
Query: 704 ERRVPDE-AILKSII--NVSALHCFQDES---YLVLNYANQGTILDLVNWERERNGGALD 757
E + +E A+L+ I N+ AL + YLV+ + G + D R G
Sbjct: 63 ESSIENEIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGGELFD-----RIVEKGFYT 117
Query: 758 ECLCMFITVELMRVLECIHDVGIIHGDIKPDNCMIRFQKVSHLGKYFANGENGWNRKGIY 817
E + +++ + +H +GI+H D+KP+N + Y++ E I
Sbjct: 118 EKDASTLIRQVLDAVYYLHRMGIVHRDLKPENLL-----------YYSQDE----ESKIM 162
Query: 818 LIDFGRSFDLSLFPLGTKFRSNWKTDQQDCPEMREQRPWSYEADYYGLAGVIFCMLFGH- 876
+ DFG S + G + T PE+ Q+P+S D + + + + +L G+
Sbjct: 163 ISDFGLS---KMEGKGDVMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYP 219
Query: 877 --YIET-----VKVASNRYQLKSPLKRYWQQDIWNPLFDLLIN 912
Y E ++ Y+ SP YW DI + D + N
Sbjct: 220 PFYDENDSKLFEQILKAEYEFDSP---YW-DDISDSAKDFIRN 258
>Hs6005814 [R] KOG0605 NDR and related serine/threonine kinases
Length = 465
Score = 51.2 bits (121), Expect = 8e-06
Identities = 57/234 (24%), Positives = 104/234 (44%), Gaps = 31/234 (13%)
Query: 665 LGEGGYATVYLAESS-TGQLSALKVEKPASVWEFYILKQI--ERRVPDEAILKSIINVSA 721
+G G + V L + TG + A+K+ + A + E + I ER + EA S+ V
Sbjct: 95 IGRGAFGEVRLVQKKDTGHVYAMKILRKADMLEKEQVGHIRAERDILVEA--DSLWVVKM 152
Query: 722 LHCFQDES--YLVLNYANQGTILDLVNWERERNGGALDECLCMFITVELMRVLECIHDVG 779
+ FQD+ YL++ + G ++ L+ L E F E + ++ IH +G
Sbjct: 153 FYSFQDKLNLYLIMEFLPGGDMMTLL-----MKKDTLTEEETQFYIAETVLAIDSIHQLG 207
Query: 780 IIHGDIKPDNCMIRFQ---KVSHLGKYFANGENGWNRKGIYL-IDFGRSFDLSLFPLGTK 835
IH DIKPDN ++ + K+S G G +R Y ++ D + + +K
Sbjct: 208 FIHRDIKPDNLLLDSKGHVKLSDFG--LCTGLKKAHRTEFYRNLNHSLPSDFTFQNMNSK 265
Query: 836 FRS-NWKTDQQD------------CPEMREQRPWSYEADYYGLAGVIFCMLFGH 876
++ WK +++ PE+ Q ++ D++ L +++ ML G+
Sbjct: 266 RKAETWKRNRRQLAFSTVGTPDYIAPEVFMQTGYNKLCDWWSLGVIMYEMLIGY 319
>Hs5730055 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 685
Score = 51.2 bits (121), Expect = 8e-06
Identities = 51/224 (22%), Positives = 101/224 (44%), Gaps = 28/224 (12%)
Query: 655 TNDLYCIRRELGEGGYATVY-LAESSTGQLSALKVEKPASVWEFYILKQIERRVPDEAIL 713
T YC + LG+GG+A Y + + + ++ A K+ + V + + ++I++ + IL
Sbjct: 78 TGKRYCRGKVLGKGGFAKCYEMTDLTNNKVYAAKIIPHSRVAKPHQREKIDKEIELHRIL 137
Query: 714 KSIINVSALHCFQDES--YLVLNYANQGTILDLVNWERERNGGALDECLCMFITVELMRV 771
V H F+D+ Y++L Y ++ ++ ++ + L E + +++
Sbjct: 138 HHKHVVQFYHYFEDKENIYILLEYCSRRSMAHILKARK-----VLTEPEVRYYLRQIVSG 192
Query: 772 LECIHDVGIIHGDIKPDNCMIRFQKVSHLGKYFANGENGWNRKGIYLIDFGRSFDLSLFP 831
L+ +H+ I+H D+K LG +F N + + DFG + L P
Sbjct: 193 LKYLHEQEILHRDLK-------------LGNFFIN-----EAMELKVGDFGLAARLE--P 232
Query: 832 LGTKFRSNWKTDQQDCPEMREQRPWSYEADYYGLAGVIFCMLFG 875
L + R+ T PE+ ++ E+D + L V++ ML G
Sbjct: 233 LEHRRRTICGTPNYLSPEVLNKQGHGCESDIWALGCVMYTMLLG 276
>Hs4502553 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 370
Score = 51.2 bits (121), Expect = 8e-06
Identities = 65/261 (24%), Positives = 114/261 (42%), Gaps = 55/261 (21%)
Query: 657 DLYCIRRELGEGGYATVYLAESS-TGQLSALK-VEKPASVWEFYILKQIERRVPDE-AIL 713
D+Y R LG G ++ V LAE T +L A+K + K A L+ E + +E A+L
Sbjct: 18 DIYDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAKEA-------LEGKEGSMENEIAVL 70
Query: 714 KSII--NVSALHCFQDES---YLVLNYANQGTILDLV---NWERERNGGALDECLCMFIT 765
I N+ AL + YL++ + G + D + + ER+ L
Sbjct: 71 HKIKHPNIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRL--------I 122
Query: 766 VELMRVLECIHDVGIIHGDIKPDNCMIRFQKVSHLGKYFANGENGWNRKGIYLIDFGRSF 825
+++ ++ +HD+GI+H D+KP+N + Y++ E+ I + DFG S
Sbjct: 123 FQVLDAVKYLHDLGIVHRDLKPENLL-----------YYSLDED----SKIMISDFGLS- 166
Query: 826 DLSLFPLGTKFRSNWKTDQQDCPEMREQRPWSYEADYYGLAGVIFCMLFGH---YIET-- 880
+ G+ + T PE+ Q+P+S D + + + + +L G+ Y E
Sbjct: 167 --KMEDPGSVLSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDA 224
Query: 881 ---VKVASNRYQLKSPLKRYW 898
++ Y+ SP YW
Sbjct: 225 KLFEQILKAEYEFDSP---YW 242
>ECU07g0360 [D] KOG0580 Serine/threonine protein kinase
Length = 272
Score = 51.2 bits (121), Expect = 8e-06
Identities = 40/141 (28%), Positives = 65/141 (45%), Gaps = 7/141 (4%)
Query: 655 TNDLYCIRRELGEGGYATVYLA-ESSTGQLSALKVEKPASVWEFYILKQIERRVPDEAIL 713
T D + I R LG G + V+LA E G + ALK+ + +QI R + + L
Sbjct: 6 TLDRFEIGRLLGRGKFGQVWLAREREKGFIVALKIIPIKEIQTVETARQIRREIEIHSNL 65
Query: 714 K--SIINVSALHCFQDESYLVLNYANQGTILDLVNWERERNGGALDECLCMFITVELMRV 771
K +I+ + +D YL+L YA +G ++ GG E ++M
Sbjct: 66 KHPNILRMYGHFHDKDNIYLILEYAGKGEFFKFLS----DRGGKFGEKETSLYIRQVMLA 121
Query: 772 LECIHDVGIIHGDIKPDNCMI 792
L + + +IH DIKP+N ++
Sbjct: 122 LTYMKECNVIHRDIKPENLLL 142
>CE21086 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 637
Score = 51.2 bits (121), Expect = 8e-06
Identities = 42/147 (28%), Positives = 73/147 (49%), Gaps = 13/147 (8%)
Query: 653 KKTNDLYCIRRELGEGGYATVYLAESSTGQLSALKVEKPASVW--EFYILKQIERRVPDE 710
KK+ D Y LGEG +A V L + G + + K S+ + ++ I+R +
Sbjct: 12 KKSKDSYEFIENLGEGSFAEVVLV-AKVGTPNKMFAMKEISIVGKDECFMESIKRECSIQ 70
Query: 711 AILKSIINVSALHCFQ----DESY-LVLNYANQGTILDLVNWERERNGGALDECLCMFIT 765
L +++ +H F+ E+Y L+L+YA+ G + + +N + G DE F
Sbjct: 71 KRLSKSRHLNMIHLFEIRTNPENYQLILSYADGGDLFEKIN---QHGGLGSDEAHRYF-- 125
Query: 766 VELMRVLECIHDVGIIHGDIKPDNCMI 792
+L+ L IH+ G+ H DIKP+N ++
Sbjct: 126 KQLIDGLRFIHEEGVTHRDIKPENLLL 152
>CE13844 [D] KOG0608 Warts/lats-like serine threonine kinases
Length = 908
Score = 51.2 bits (121), Expect = 8e-06
Identities = 43/149 (28%), Positives = 72/149 (47%), Gaps = 20/149 (13%)
Query: 653 KKTNDLYCIRRELGEGGYATVYLA-ESSTGQLSALKVEKPASVWEFYILKQ------IER 705
K + + + +G G + V L ++ T ++ A+K + A V I+KQ ER
Sbjct: 496 KMSKSHFTVISHIGVGAFGKVSLVRKNDTRKVYAMKSLEKADV----IMKQQAAHVKAER 551
Query: 706 RVPDEAILKSIINVSALHCFQDES--YLVLNYANQGTILDLVNWERERNGGALDECLCMF 763
+ EA I+ + FQD++ Y ++ Y G ++ L+ + G +E L F
Sbjct: 552 DILAEADSPWIVRL--FFSFQDDACLYFIMEYVPGGDMMTLLIQK-----GIFEEDLARF 604
Query: 764 ITVELMRVLECIHDVGIIHGDIKPDNCMI 792
EL +E +H+VG IH D+KPDN +I
Sbjct: 605 YIAELACAIEYVHNVGFIHRDLKPDNILI 633
>At4g14580 [T] KOG0583 Serine/threonine protein kinase
Length = 426
Score = 51.2 bits (121), Expect = 8e-06
Identities = 47/154 (30%), Positives = 78/154 (50%), Gaps = 20/154 (12%)
Query: 659 YCIRRELGEGGYATVYLAES-STGQLSALKV-EKPASV---WEFYILKQIE--RRVPDEA 711
Y + R LG G +A V++A S STG+L A+K+ +K ++ E I+++IE RR+ +
Sbjct: 21 YELGRRLGSGSFAKVHVARSISTGELVAIKIIDKQKTIDSGMEPRIIREIEAMRRLHNHP 80
Query: 712 ILKSIINVSALHCFQDESYLVLNYANQGTILD-LVNWERERNGGALDECLCMFITVELMR 770
+++ + + + + YLV+ YA G + L+ + G L+E +L
Sbjct: 81 ---NVLKIHEVMATKSKIYLVVEYAAGGELFTKLIRF------GRLNESAARRYFQQLAS 131
Query: 771 VLECIHDVGIIHGDIKPDNCMIRFQ---KVSHLG 801
L H GI H D+KP N ++ Q KVS G
Sbjct: 132 ALSFCHRDGIAHRDVKPQNLLLDKQGNLKVSDFG 165
>At3g51850 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 503
Score = 51.2 bits (121), Expect = 8e-06
Identities = 61/234 (26%), Positives = 97/234 (41%), Gaps = 36/234 (15%)
Query: 651 DFKKTN--DLYCIRRELGEGGYATVYLA-ESSTGQLSALKVEKPASVWEFYILKQIERRV 707
D K N D Y + RELG G + YL E S+ L A K + ++ ++R V
Sbjct: 44 DVPKENIEDRYLLDRELGRGEFGVTYLCIERSSRDLLACKSISKRKLRTAVDIEDVKREV 103
Query: 708 PDEAILKSIINVSAL-----HCFQDES-YLVLNYANQGTILDLVNWERERNGGALDECLC 761
AI+K + S++ C D + +LV+ G + D + G E
Sbjct: 104 ---AIMKHLPKSSSIVTLKEACEDDNAVHLVMELCEGGELFDRIVAR-----GHYTERAA 155
Query: 762 MFITVELMRVLECIHDVGIIHGDIKPDNCMIRFQKVSHLGKYFANGENGWNRKGIYLIDF 821
+T ++ V++ H G+IH D+KP+N + FAN + K IDF
Sbjct: 156 AGVTKTIVEVVQLCHKHGVIHRDLKPENFL------------FANKKENSPLKA---IDF 200
Query: 822 GRSFDLSLFPLGTKFRSNWKTDQQDCPEMREQRPWSYEADYYGLAGVIFCMLFG 875
G S F G KF + PE+ +R + E D + +++ +L G
Sbjct: 201 GLSI---FFKPGEKFSEIVGSPYYMAPEVL-KRNYGPEIDIWSAGVILYILLCG 250
>SPCC576.15c [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 592
Score = 50.8 bits (120), Expect = 1e-05
Identities = 59/236 (25%), Positives = 102/236 (43%), Gaps = 34/236 (14%)
Query: 665 LGEGGYATVYLA-ESSTGQLSALKVEKPASVWEFYILKQIERRVPDEAILKSIIN----- 718
LGEG Y+TV A E+ST + A+KV + I ++ E+ V E I++
Sbjct: 105 LGEGSYSTVLTATENSTKREYAIKVLDKRHI----IKEKKEKYVNIEKEALCILSKHPGF 160
Query: 719 VSALHCFQDES--YLVLNYANQGTILDLVNWERERNGGALDECLCMFITVELMRVLECIH 776
+ + FQD Y VL+ A G +LD +N G +E + ++ ++ +H
Sbjct: 161 IKLFYTFQDAHNLYFVLSLARNGELLDYIN-----KLGRFNEICAQYYAALIVDSIDYMH 215
Query: 777 DVGIIHGDIKPDNCMI---RFQKVSHLGK-YFANGENGWNRKGIYLIDFGRSFDLSLFPL 832
G+IH D+KP+N ++ K++ G N +G + + + D ++
Sbjct: 216 GRGVIHRDLKPENILLDDNMRTKITDFGSAKILNSSHGSHEEDTHHADKPQAHS------ 269
Query: 833 GTKFRSNWKTDQQDCPEMREQRPWSYEADYYGLAGVIFCMLFGHYIETVKVASNRY 888
RS T + PE+ + +D + ++F ML G + VA N Y
Sbjct: 270 ----RSFVGTARYVSPEVLSDKIAGTASDIWAFGCILFQMLAG---KPPFVAGNEY 318
>SPCC1450.11c [R] KOG0605 NDR and related serine/threonine kinases
Length = 1338
Score = 50.8 bits (120), Expect = 1e-05
Identities = 47/153 (30%), Positives = 71/153 (45%), Gaps = 16/153 (10%)
Query: 647 NPIVDFKKTNDLYCIRRELGEGGYATVYLAES-STGQLSALKVEKPASVWEFYILKQIER 705
N + ND Y I + + +G + +VYLA+ +TG A+K+ K +++ Q+
Sbjct: 578 NSAPEHPSIND-YKILKPISKGAFGSVYLAQKRTTGDYFAIKILKKSNM---IAKNQVIN 633
Query: 706 RVPDEAIL----KSIINVSALHCFQ--DESYLVLNYANQGTILDLVNWERERNGGALDEC 759
+ AIL +S + FQ D YLV+ Y N G L+ + G LD
Sbjct: 634 VRAERAILMSQGESPFVAKLYYTFQSKDYLYLVMEYLNGGDCGSLL-----KTMGVLDLD 688
Query: 760 LCMFITVELMRVLECIHDVGIIHGDIKPDNCMI 792
E + L +HD GIIH DIKP+N +I
Sbjct: 689 WIRTYIAETVLCLGDLHDRGIIHRDIKPENLLI 721
>SPBC106.10 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 512
Score = 50.8 bits (120), Expect = 1e-05
Identities = 58/233 (24%), Positives = 106/233 (44%), Gaps = 41/233 (17%)
Query: 655 TNDLYCIR-----RELGEGGYATVYLAESSTGQLS-ALKVEKPASVWEFYILKQIERRVP 708
T D Y I+ + LG G + V+L +S+ +L A+KV + + + +KQIE
Sbjct: 192 TKDRYGIQDFNFLQTLGTGSFGRVHLVQSNHNRLYYAIKVLEKKKIVD---MKQIEHTCD 248
Query: 709 DEAILKSIIN--VSALH-CFQDES--YLVLNYANQGTILDLVNWERERNGGALDECLCMF 763
+ IL + + ++ L FQD ++V+++A G + L+ R E + F
Sbjct: 249 ERYILSRVQHPFITILWGTFQDAKNLFMVMDFAEGGELFSLL-----RKCHRFPEKVAKF 303
Query: 764 ITVELMRVLECIHDVGIIHGDIKPDNCMIRFQKVSHLGKYFANGENGWNRKGIYLIDFGR 823
E++ L+ +H I++ D+KP+N ++ + HL ++DFG
Sbjct: 304 YAAEVILALDYLHHNQIVYRDLKPENLLL--DRFGHL----------------KIVDFGF 345
Query: 824 SFDLSLFPLGTKFRSNWKTDQQDCPEMREQRPWSYEADYYGLAGVIFCMLFGH 876
+ +S T T PE+ +P++ AD++ L +IF ML G+
Sbjct: 346 AKRVSTSNCCTL----CGTPDYLAPEIISLKPYNKAADWWSLGILIFEMLAGY 394
>Hs5453972 [T] KOG0694 Serine/threonine protein kinase
Length = 682
Score = 50.8 bits (120), Expect = 1e-05
Identities = 54/221 (24%), Positives = 91/221 (40%), Gaps = 35/221 (15%)
Query: 663 RELGEGGYATVYLAE-SSTGQLSALKVEKPASVWEFYILKQIERRVPDEAILKSIINVSA 721
R LG+G + V LA TG L A+KV K + + +E + ++ IL N
Sbjct: 358 RVLGKGSFGKVMLARVKETGDLYAVKVLKKDVI---LLDDDVECTMTEKRILSLARNHPF 414
Query: 722 LH----CFQ--DESYLVLNYANQGTILDLVNWERERNGGALDECLCMFITVELMRVLECI 775
L CFQ D + V+ + N G ++ + R DE F E++ L +
Sbjct: 415 LTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSRR-----FDEARARFYAAEIISALMFL 469
Query: 776 HDVGIIHGDIKPDNCMIRFQKVSHLGKYFANGENGWNRKGIYLIDFGRSFDLSLFPLGTK 835
HD GII+ D+K DN ++ + L + G ++GI G
Sbjct: 470 HDKGIIYRDLKLDNVLLDHEGHCKLADF------GMCKEGIC--------------NGVT 509
Query: 836 FRSNWKTDQQDCPEMREQRPWSYEADYYGLAGVIFCMLFGH 876
+ T PE+ ++ + D++ + +++ ML GH
Sbjct: 510 TATFCGTPDYIAPEILQEMLYGPAVDWWAMGVLLYEMLCGH 550
>At5g04510 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 488
Score = 50.8 bits (120), Expect = 1e-05
Identities = 43/134 (32%), Positives = 65/134 (48%), Gaps = 16/134 (11%)
Query: 666 GEGGYATVYLAESS-TGQLSALKVEKPASVWE----FYILKQIERRVPDEAILKSIINVS 720
G G Y+ V A+ TG + ALK+ + + Y+ ++ER V D+ II +
Sbjct: 48 GVGSYSKVVRAKKKETGTVYALKIMDKKFITKENKTAYV--KLERIVLDQLEHPGIIKL- 104
Query: 721 ALHCFQDES--YLVLNYANQGTILDLVNWERERNGGALDECLCMFITVELMRVLECIHDV 778
FQD S Y+ L G + D + + G L E F T E++ LE IH +
Sbjct: 105 -YFTFQDTSSLYMALESCEGGELFDQITRK-----GRLSEDEARFYTAEVVDALEYIHSM 158
Query: 779 GIIHGDIKPDNCMI 792
G+IH DIKP+N ++
Sbjct: 159 GLIHRDIKPENLLL 172
>At3g27580 [R] KOG0610 Putative serine/threonine protein kinase
Length = 578
Score = 50.8 bits (120), Expect = 1e-05
Identities = 42/137 (30%), Positives = 74/137 (53%), Gaps = 12/137 (8%)
Query: 663 RELGEGGYATVYLAES-STGQLSALKVEKPASVWEFYILKQIERRVPDEAILKSIIN--V 719
++LG G VYLAE TG A+KV + A++ K++ R ++ IL+S+ + +
Sbjct: 186 KKLGGGDIGNVYLAELIGTGVSFAVKVMEKAAI---AARKKLVRAQTEKEILQSLDHPFL 242
Query: 720 SALHC-FQDE--SYLVLNYANQGTILDLVNWERERNGGALDECLCMFITVELMRVLECIH 776
L+ F+ E S LV+ + G DL + +++ G E F E++ +E +H
Sbjct: 243 PTLYSHFETEMNSCLVMEFCPGG---DLHSLRQKQRGKYFPEQAARFYVAEVLLAMEYLH 299
Query: 777 DVGIIHGDIKPDNCMIR 793
+GII+ D+KP+N ++R
Sbjct: 300 MLGIIYRDLKPENVLVR 316
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.316 0.134 0.387
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 57,954,418
Number of Sequences: 60738
Number of extensions: 2616195
Number of successful extensions: 10299
Number of sequences better than 1.0e-05: 80
Number of HSP's better than 0.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 74
Number of HSP's that attempted gapping in prelim test: 10164
Number of HSP's gapped (non-prelim): 113
length of query: 959
length of database: 30,389,216
effective HSP length: 116
effective length of query: 843
effective length of database: 23,343,608
effective search space: 19678661544
effective search space used: 19678661544
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)