ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI6055 good P KOG1161 Inorganic ion transport and metabolism Protein involved in vacuolar polyphosphate accumulation, contains SPX domain
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI6055 2114525 2112339 -729
(729 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YJL012c [P] KOG1161 Protein involved in vacuolar polyphosphate a... 942 0.0
SPCC1322.14c_1 [P] KOG1161 Protein involved in vacuolar polyphos... 688 0.0
ECU06g1420i_1 [P] KOG1161 Protein involved in vacuolar polyphosp... 302 1e-81
SPAC14C4.11_1 [P] KOG1161 Protein involved in vacuolar polyphosp... 275 2e-73
YFL004w_1 [P] KOG1161 Protein involved in vacuolar polyphosphate... 273 7e-73
YPL019c_1 [P] KOG1161 Protein involved in vacuolar polyphosphate... 271 3e-72
YER072w [UO] KOG4580 Component of vacuolar transporter chaperone... 92 3e-18
SPBC21B10.04c [UO] KOG4580 Component of vacuolar transporter cha... 92 3e-18
SPCC1322.14c_2 [UO] KOG4580 Component of vacuolar transporter ch... 90 1e-17
ECU06g1420i_2 [UO] KOG4580 Component of vacuolar transporter cha... 85 4e-16
At2g26660 [P] KOG1161 Protein involved in vacuolar polyphosphate... 66 2e-10
At5g20150 [P] KOG1161 Protein involved in vacuolar polyphosphate... 62 3e-09
At2g45130 [P] KOG1161 Protein involved in vacuolar polyphosphate... 62 3e-09
Hs19923272 [U] KOG1162 Predicted small molecule transporter 53 1e-06
7295413 [U] KOG1162 Predicted small molecule transporter 52 2e-06
7293416 [U] KOG1162 Predicted small molecule transporter 52 4e-06
At5g15330 [P] KOG1161 Protein involved in vacuolar polyphosphate... 50 9e-06
>YJL012c [P] KOG1161 Protein involved in vacuolar polyphosphate accumulation
contains SPX domain
Length = 648
Score = 942 bits (2436), Expect = 0.0
Identities = 465/627 (74%), Positives = 522/627 (83%), Gaps = 27/627 (4%)
Query: 2 VKFGEHLKRSLIREYSYYYISYNDLKTELQESLEANNGKWNEDLETQFLESLEIELDKVY 61
+KFGEHL +SLIR+YSYYYISY+DLKTEL+++L NNG+W ++LET FLESLEIELDKVY
Sbjct: 1 MKFGEHLSKSLIRQYSYYYISYDDLKTELEDNLSKNNGQWTQELETDFLESLEIELDKVY 60
Query: 62 TFCKVKHNEVVRRIKQAQEQVSVAVRSLDTNVPVTDLDFQILEEELSDIIADVHDLAKFA 121
TFCKVKH+EV RR+K+ QEQV VR LD+N P T LDF+ILEEELSDIIADVHDLAKF+
Sbjct: 61 TFCKVKHSEVFRRVKEVQEQVQHTVRLLDSNNPPTQLDFEILEEELSDIIADVHDLAKFS 120
Query: 122 RLNYTGLQKIIKKHDKNTNFILKPIFQVRMDAKPFFKENYDELVVKLSQLYDIVRTRGNP 181
RLNYTG QKIIKKHDK T FILKP+FQVR+D+KPFFKENYDELVVK+SQLYDI RT G P
Sbjct: 121 RLNYTGFQKIIKKHDKKTGFILKPVFQVRLDSKPFFKENYDELVVKISQLYDIARTSGRP 180
Query: 182 VKGDSAAGGKQQNFVRQTTKYWVHPDNITELKLIILKHLPVLVFNTNKEFEKEDSAITSI 241
+KGDS+AGGKQQNFVRQTTKYWVHPDNITELKLIILKHLPVLVFNTNKEFE+EDSAITSI
Sbjct: 181 IKGDSSAGGKQQNFVRQTTKYWVHPDNITELKLIILKHLPVLVFNTNKEFEREDSAITSI 240
Query: 242 YYDNEDLDLYYGRLRKDEGAEAHRLRWYGGMSSDTIFVERKTHREDWTGEKSVKARFALK 301
Y+DNE+LDLYYGRLRKDEGAEAHRLRWYGGMS+DTIFVERKTHREDWTGEKSVKARFALK
Sbjct: 241 YFDNENLDLYYGRLRKDEGAEAHRLRWYGGMSTDTIFVERKTHREDWTGEKSVKARFALK 300
Query: 302 EKYVNDFLHGKYTVEQAFAKMRREGKKSIQEIENLEALATETQYTMLKKKLRPVARSFYN 361
E++VNDFL GKYTV+Q FAKMR+EGKK + EIENLEALA+E QY MLKKKLRPV RSFYN
Sbjct: 301 ERHVNDFLKGKYTVDQVFAKMRKEGKKPMNEIENLEALASEIQYVMLKKKLRPVVRSFYN 360
Query: 362 RTAFQLPGDARVRISLDTELSMVREDNFDGHDRTNGNWRRMDIGVDWPFNQLPEKDICRF 421
RTAFQLPGDARVRISLDTEL+MVREDNFDG DRT+ NWRR DIGVDWPF QL +KDICRF
Sbjct: 361 RTAFQLPGDARVRISLDTELTMVREDNFDGVDRTHKNWRRTDIGVDWPFKQLDDKDICRF 420
Query: 422 PYAVLEVKLQTQMGQEPPEWVRELVGSHLVEPVPKFSKFIHGVASLLNDRVSSIPFWLPQ 481
PYAVLEVKLQTQ+GQEPPEWVRELVGSHLVEPVPKFSKFIHGVA+LLND+V SIPFWLPQ
Sbjct: 421 PYAVLEVKLQTQLGQEPPEWVRELVGSHLVEPVPKFSKFIHGVATLLNDKVDSIPFWLPQ 480
Query: 482 MDVDIRKPAIPTHINITRPGRX---------XXXXXXXXXXXXLAAPGNSYDIXXXXXXX 532
MDVDIRKP +PT+I ITRPGR APGNS DI
Sbjct: 481 MDVDIRKPPLPTNIEITRPGRSDNEDNDFDEDDEDDAALVAAMTNAPGNSLDI------- 533
Query: 533 XXXXXXQSSTGNYGSITQDSARAGNTADSPAASENSAALLRNIRQASNPVAKYWHTLVYQ 592
+ S G YG+ + ++ + + S N+A R IR A NP++K ++ +V
Sbjct: 534 ------EESVG-YGATSAPTSNTNHVVE----SANAAYYQRKIRNAENPISKKYYEIVAF 582
Query: 593 IDHYLYGDQVSKVPEGTVFDTYVHAPP 619
DHY GDQ+SK+P+GT FDT + APP
Sbjct: 583 FDHYFNGDQISKIPKGTTFDTQIRAPP 609
>SPCC1322.14c_1 [P] KOG1161 Protein involved in vacuolar polyphosphate accumulation
contains SPX domain
Length = 608
Score = 688 bits (1775), Expect = 0.0
Identities = 336/494 (68%), Positives = 401/494 (81%), Gaps = 5/494 (1%)
Query: 2 VKFGEHLKRSLIREYSYYYISYNDLKTELQESLEANNGKWNEDLETQFLESLEIELDKVY 61
+KFG+ LK +L+ EY Y Y++Y+ LK E++ + G W+E+ E+ F+E LE ELDKVY
Sbjct: 1 MKFGQLLKETLMYEYKYSYVNYDKLKKEIKR--RNDQGGWSEEDESDFVELLEKELDKVY 58
Query: 62 TFCKVKHNEVVRRIKQAQEQVSVAVRSLDTNVPVTDLDFQILEEELSDIIADVHDLAKFA 121
+F K K EV+ RI+ +EQ VR LD++ P + DF ILE EL+DI+A VHDLAKF+
Sbjct: 59 SFQKNKSAEVMERIRFCEEQTDEVVRRLDSDNPPNENDFAILETELTDIMATVHDLAKFS 118
Query: 122 RLNYTGLQKIIKKHDKNTNFILKPIFQVRMDAKPFFKENYDELVVKLSQLYDIVRTRGNP 181
LNYT KIIKKHDK+T +ILKP+F R++AKPFFKE YD LVVKLS+LYD VRTRG+P
Sbjct: 119 ELNYTAFYKIIKKHDKHTGWILKPVFAARLNAKPFFKEQYDLLVVKLSKLYDFVRTRGSP 178
Query: 182 VKGDSAAGGKQQNFVRQTTKYWVHPDNITELKLIILKHLPVLVFNTNKEFEKEDSAITSI 241
+KGDSAAGG QQNFVRQTTKYWVHP+N+TELK+ ILKHLPVLVFN NKEF +ED+AITSI
Sbjct: 179 IKGDSAAGGTQQNFVRQTTKYWVHPNNVTELKIYILKHLPVLVFNPNKEFAREDAAITSI 238
Query: 242 YYDNEDLDLYYGRLRKDEGAEAHRLRWYGGMSSDTIFVERKTHREDWTGEKSVKARFALK 301
YYDN+DLD Y GRL K EGAEA RLRWYG M ++ IFVERKTHREDWTGEKSVKARF LK
Sbjct: 239 YYDNDDLDFYLGRLEKREGAEAIRLRWYGNMDNNNIFVERKTHREDWTGEKSVKARFPLK 298
Query: 302 EKYVNDFLHGKYTVEQAFAKMRREGKKSIQEIENLEALATETQYTMLKKKLRPVARSFYN 361
EKYVN FL G YTVE+AFAKMR++GKKS++EIE+LE LA E QYT+L + ++P RSFY
Sbjct: 299 EKYVNAFLRGDYTVEEAFAKMRKDGKKSLKEIESLERLAKEVQYTVLSRGMKPYVRSFYE 358
Query: 362 RTAFQLPGDARVRISLDTELSMVREDNFDGHDRTNGNWRRMDIGVDWPFNQLPEKDICRF 421
RTAFQLPGDARVRISLDT LS++RE DG R NWRRMDIG+D+PF+QLP++DI RF
Sbjct: 359 RTAFQLPGDARVRISLDTNLSLIRE---DGPSRAGNNWRRMDIGIDYPFDQLPDEDIVRF 415
Query: 422 PYAVLEVKLQTQMGQEPPEWVRELVGSHLVEPVPKFSKFIHGVASLLNDRVSSIPFWLPQ 481
PYA+LEVKLQTQ GQ+PPEWV LV SHLVE VPKFSKFIHGV++L DRV+ +P+W PQ
Sbjct: 416 PYAILEVKLQTQFGQDPPEWVNNLVNSHLVEAVPKFSKFIHGVSTLFYDRVTLLPYWFPQ 475
Query: 482 MDVDIRKPAIPTHI 495
MD+DIRKPA T I
Sbjct: 476 MDIDIRKPATHTFI 489
>ECU06g1420i_1 [P] KOG1161 Protein involved in vacuolar polyphosphate accumulation
contains SPX domain
Length = 497
Score = 302 bits (774), Expect = 1e-81
Identities = 171/511 (33%), Positives = 283/511 (54%), Gaps = 56/511 (10%)
Query: 2 VKFGEHLKRSLIREYSYYYISYNDLKTELQESLEANNGKWNEDLETQFLESLEIELDKVY 61
++F ++LKR+L Y Y Y+ Y +L+ ++ A++ E +F+ L+ + +V+
Sbjct: 1 MRFQKYLKRNLYAPYKYNYLDYENLRERFKKEGFASSD------EDEFVRELDANIKRVF 54
Query: 62 TFCKVKHNEVVRRIKQAQEQVSVAVRSLDTNVPVTDLDFQILEEELSDIIADVHDLAKFA 121
F + K++E V+R++ +++ RS ++ ++ ++ A+F
Sbjct: 55 GFVESKYSEFVQRLRTLEKKPPKEARS-----------------KIKEMTEEMRHFAEFI 97
Query: 122 RLNYTGLQKIIKKHDKNTNFILKPIFQVRMDAKPFFKENYDELVVKLSQL-YDIVRTRGN 180
R+N G +K++++HDK+T + L P ++ + K E+ DEL+ K S++ + T+
Sbjct: 98 RINVIGFKKLLRRHDKHTEYRLLPSYKPMLKGKIKSVEDLDELIYKASRISLKAIETKKK 157
Query: 181 PVKGDSAAGGKQQNFVRQTTKYWVHPDNITELKLIILKHLPVLVFNTNKEFEK------- 233
+ + F+R T KYWVH +N+ +K I +HLP+ VF+ E +
Sbjct: 158 NTESNCM-------FIRMTDKYWVHKENVVPVKFYITQHLPIYVFSKGNEEKSPYSSWDK 210
Query: 234 --EDSAITSIYYDNEDLDLYYGRLRKDEGAEAHRLRWYGGMSSDTIFVERKTHREDWTGE 291
D+ I+S+Y+DN DLY RL+K +EA R+RWY D +FVERK H + WTGE
Sbjct: 211 NSHDTCISSVYFDNVAFDLYGERLKKLHHSEAIRIRWYTSEVPDVVFVERKKHEDGWTGE 270
Query: 292 KSVKARFALKEKYVNDFLHGKYTVEQAFAKMRREGKKSIQEIENLEALATETQYTMLKKK 351
S K RF + EK V +++G E + +RR + E++ L E Q +++ +
Sbjct: 271 SSKKLRFMINEKQVLKYING----EDVWEDVRR-----LNGDEDVRMLYEEVQSSIVNRG 321
Query: 352 LRPVARSFYNRTAFQLPGDARVRISLDTELSMVRE---DNFDGHDRTNGNWRRMDIGVDW 408
LRPV R+FY R+AFQ+P D+ VR+SLDT+L M++E WRR D+ D+
Sbjct: 322 LRPVVRTFYRRSAFQIPNDSSVRVSLDTDLCMIKECSDAEIVNPTYPITRWRRSDVNCDF 381
Query: 409 PFNQLPEKDICRFPYAVLEVKLQTQMGQEPPEWVRELVGSHLVEPVPKFSKFIHGVASLL 468
PF +P+ +I RFP+A+LE+K Q + P+W+ EL+ LVE V KFSK++HG A +L
Sbjct: 382 PFRNVPKSEIVRFPHAILEIKTQ-NFDETKPKWIEELINGPLVEHVHKFSKYLHGCA-VL 439
Query: 469 NDRVSSIPFWLPQMDVDIRKPAIPTHINITR 499
+ IP+WLPQ+ VDIRK P H ++ +
Sbjct: 440 YPFIQDIPYWLPQVAVDIRKD--PFHPDVDK 468
>SPAC14C4.11_1 [P] KOG1161 Protein involved in vacuolar polyphosphate accumulation
contains SPX domain
Length = 606
Score = 275 bits (702), Expect = 2e-73
Identities = 171/512 (33%), Positives = 276/512 (53%), Gaps = 41/512 (8%)
Query: 2 VKFGEHLKRSLIREYSYYYISYNDLKTELQESLEANNGKWNEDLETQFLESLEIELDKVY 61
++F + ++ + + Y++Y +LK L+ EA + W E+ E++F+ ++ +L+KVY
Sbjct: 1 MRFSDSIEAGIYEPWRDKYMNYPELKHLLKTEEEAPS--WGENDESKFVSVMDAQLEKVY 58
Query: 62 TFCKVKHNEVVRRIKQAQEQVS--VAVRSLDTNVPVTDLDFQILEEELSDIIADVHDLAK 119
F H E+++ + ++ + V V+ P++ + L E L V L K
Sbjct: 59 AF----HLEILKELNESVDWVKSKVSASQEPDGPPISKEEAIKLLERLDSCTETVKKLEK 114
Query: 120 FARLNYTGLQKIIKKHDK-NTNFILKPIFQVRMDAKPFFKENYDELVVKLSQLYDIVRTR 178
+ RLN TG KI+KKHDK + L+P+FQVR+ A P ++ L+ ++ LY+ +R
Sbjct: 115 YTRLNLTGFFKIVKKHDKLYPGYSLRPVFQVRLRACPLGSVQFNPLLAEIFSLYNTLRDG 174
Query: 179 GNPVKGDSAAGGKQQNFV--------RQTTKYWVHPDNITELKLIILKHLPVLVFNTNKE 230
+ K ++ V R+T ++WVHPDN+ E+K I++HLPVL ++ +
Sbjct: 175 LSAPSNSVQVKPKHEHNVDYNSSMYRRRTFRFWVHPDNVMEVKTYIMRHLPVLYYSGKQG 234
Query: 231 FEKEDSAI--------TSIYYDNEDLDLYYGRLRKDEGAEAHRLRWYGGMSSDTIFVERK 282
F+K+ + + T +Y DN + DLY L + E A + RL WYG ++ T + +
Sbjct: 235 FDKDQNGVSGILDPISTCLYLDNSNFDLYSQNLERSEQAYSLRLHWYGKLTPKTDIIVER 294
Query: 283 THREDWTGEKSVKARFALKEKYVNDFLHGKYT---VEQAFAKMRREGKKSIQEIENLEAL 339
R+ T S + RF ++EK V + L G+Y VE + + KK + IE++E L
Sbjct: 295 MVRQGSTLSHS-EDRFTIREKKVRELLSGRYDFRKVEDDHSTTASDQKKKL--IEDVEQL 351
Query: 340 ATETQYTMLKKKLRPVARSFYNRTAFQLPGDARVRISLDTELSMVREDNFDGHD--RTNG 397
+ L+PV RS Y RTAFQ+PGD VRI+LD++ M+RED+ D R
Sbjct: 352 IVDNH-------LQPVLRSVYTRTAFQIPGDDEVRINLDSDWVMIREDSLDIERPCRDPE 404
Query: 398 NWRRMDIG-VDWPFNQLPEKDICRFPYAVLEVKLQTQMGQEPPEWVRELVGSHLVEPVPK 456
+W R DI D+P+ L + + RFPY+VLE++ + ++ P W+ EL SHL+ +
Sbjct: 405 DWHRHDIDDADFPYKHLRKGEYSRFPYSVLEIRECVRYDEDEPLWISELRNSHLISEIDG 464
Query: 457 FSKFIHGVASLLNDRVSSIPFWLPQMDVDIRK 488
FSK+ HGVA L VS +P W+ MD DIRK
Sbjct: 465 FSKYEHGVAILFEKYVSLLPMWVFSMDQDIRK 496
>YFL004w_1 [P] KOG1161 Protein involved in vacuolar polyphosphate accumulation
contains SPX domain
Length = 675
Score = 273 bits (698), Expect = 7e-73
Identities = 182/559 (32%), Positives = 290/559 (51%), Gaps = 82/559 (14%)
Query: 4 FGEHLKRSLIREYSYYYISYNDLKTELQESL--EANNGK---WNEDLETQFLESLEIELD 58
FG L + + YI+Y LK L+E + +N K W++ E++F+E L+ EL+
Sbjct: 3 FGVKLANEVYPPWKGSYINYEGLKKFLKEDSVKDGSNDKKARWDDSDESKFVEELDKELE 62
Query: 59 KVYTFCKVKHNEVVRRIKQAQEQVSVAVRSLDTNVPVTDLDFQILEEELSDIIADVHDLA 118
KVY F K+N ++ R+ ++Q DT + LD + L +++++ +L
Sbjct: 63 KVYGFQLKKYNNLMERLSHLEKQT-------DTEAAIKALDADAFQRVLEELLSESTELD 115
Query: 119 KFARLNYTGLQKIIKKHDKNTNFI--LKPIFQVRMDAKPFFKENYDELVVKLSQLYDIVR 176
F RLN+TG KI+KKHDK +K + +VR+ P E Y L+ ++S LY+I+R
Sbjct: 116 NFKRLNFTGFAKIVKKHDKLYPKYPSVKSLLEVRLKELPSHSEEYSPLLYRISFLYNILR 175
Query: 177 TRGNPVKGDSAAGGKQQNFVR-------QTTKYWVHPDNITELKLIILKHLPVLVF-NTN 228
+ N A+ K + V ++ K+WVH DN+ E+K IL+HLPVLV+ N
Sbjct: 176 SNFNTASEPLASASKFSSIVSNDIDMNFRSFKFWVHNDNLMEVKTRILRHLPVLVYANVP 235
Query: 229 KE-------FEKE--------------------------DSAITSIYYDNEDLDLYYGRL 255
E FE + D I ++Y+DNE +LY +L
Sbjct: 236 SENDDLVNRFESDISNNDEIVGSSSSTSSVEHGLGARSFDPLINTLYFDNEHFELYNDKL 295
Query: 256 RKDEGAEAHRLRWYGGMSSDT-IFVERKTHREDWTGEKSV--KARFALKEKYVNDFLH-- 310
K A RLRW G +S IF+E+KT ED KS + LK+K++N F+
Sbjct: 296 LKLNSAPTLRLRWTGQLSDKPDIFLEKKTLIEDEATGKSEFDLTKLQLKQKFINGFIFEG 355
Query: 311 GKYTVEQAFAKMRREGKKSIQEIENLEALATETQYTMLKKKLRPVARSFYNRTAFQLPGD 370
K EQ K++ G +++E LE +E Q ++K +L+PV R+ Y RTAFQ+PGD
Sbjct: 356 DKKFKEQTLKKLKESGTAG-RDLERLEEDFSEIQNFIIKNELQPVFRTVYTRTAFQIPGD 414
Query: 371 ARVRISLDTELSMVREDNFDGHD--RTNGNWRRMDI--GVDWPFNQLPEKDICRFPYAVL 426
++R+++D+ + ++ED+FD R W R DI V P L + +FPY+V+
Sbjct: 415 DKIRVTIDSNIVFIKEDSFDRERPIRDPNTWHRTDIDANVANPLKFLRGGEYAKFPYSVM 474
Query: 427 EVKLQT---------------QMGQEPPEWVRELVGSHLVEPVPKFSKFIHGVASLLND- 470
E+K+++ ++ ++ +W+ +L SHLV+ +PKFS F+ GVASL D
Sbjct: 475 EIKVKSSLDSSMSASSMISNVKLPKKHGQWLNDLTNSHLVKEIPKFSIFVQGVASLYGDD 534
Query: 471 -RVSSIPFWLPQMDVDIRK 488
++ +PFWLP ++ DIR+
Sbjct: 535 EKLDILPFWLPDLETDIRQ 553
>YPL019c_1 [P] KOG1161 Protein involved in vacuolar polyphosphate accumulation
contains SPX domain
Length = 687
Score = 271 bits (692), Expect = 3e-72
Identities = 187/569 (32%), Positives = 292/569 (50%), Gaps = 96/569 (16%)
Query: 4 FGEHLKRSLIREYSYYYISYNDLKTELQESL----EANNGKWNEDLETQFLESLEIELDK 59
FG L + + YI Y LK L+ES+ ++ W+E E+ F+E+L+ EL+K
Sbjct: 3 FGIKLANDVYPPWKDSYIDYERLKKLLKESVIHDGRSSVDSWSERNESDFVEALDKELEK 62
Query: 60 VYTFCKVKHNEVVRRIKQAQEQVSVAVRSLDTNVPVTDLDFQILEEELSDIIADVHDLAK 119
VYTF K+N V+R++ +E A + + ++ + + L + + + L
Sbjct: 63 VYTFQISKYNAVLRKLDDLEENTKSAEK-------IQKINSEQFKNTLEECLDEAQRLDN 115
Query: 120 FARLNYTGLQKIIKKHDK-NTNF-ILKPIFQVRMDAKPFFK-ENYDELVVKLSQLYDIVR 176
F RLN+TG KI+KKHDK + N+ +K + QVR+ PF E Y L+ ++S LY+ +R
Sbjct: 116 FDRLNFTGFIKIVKKHDKLHPNYPSVKSLLQVRLKELPFNNSEEYSPLLYRISYLYEFLR 175
Query: 177 TR---GNPVKGDSAAGGKQQNFVR------QTTKYWVHPDNITELKLIILKHLPVLVF-- 225
+ N V A+ K +F ++ K+WVH DNI E+K IL+HLP LV+
Sbjct: 176 SNYDHPNTVSKSLASTSKLSHFSNLEDASFKSYKFWVHDDNIMEVKARILRHLPALVYAS 235
Query: 226 -------------------------------------NTNKEFE-----------KEDSA 237
N+N++ E D
Sbjct: 236 VPNENDDFVDNLESDVRVQPEARLNIGSKSNSLSSDGNSNQDVEIGKSKSVIFPQSYDPT 295
Query: 238 ITSIYYDNEDLDLYYGRLRKDEGAEAHRLRWYGGM-SSDTIFVERKTHREDW-TGEKSVK 295
IT++Y+DN+ DLY RL K GA RLRW G + IF+E++T E+ TG S +
Sbjct: 296 ITTLYFDNDFFDLYNNRLLKISGAPTLRLRWIGKLLDKPDIFLEKRTFTENTETGNSSFE 355
Query: 296 A-RFALKEKYVNDFL------HGKYTVEQAFAKMRREGKKSIQEIENLEALATETQYTML 348
R +K K++N+F+ + Y + Q +R G + +E+E L Q ++
Sbjct: 356 EIRLQMKAKFINNFIFKNDPSYKNYLINQ----LRERGTQK-EELEKLSRDFDNIQNFIV 410
Query: 349 KKKLRPVARSFYNRTAFQLPGDARVRISLDTELSMVREDNFDGHD--RTNGNWRRMDI-- 404
++KL+PV R+ YNRTAFQ+PGD +R+++D+ + +RED+ D + R NW R DI
Sbjct: 411 EEKLQPVLRATYNRTAFQIPGDQSIRVTIDSNIMYIREDSLDKNRPIRNPENWHRDDIDS 470
Query: 405 GVDWPFNQLPEKDICRFPYAVLEVKLQTQMGQEPP--EWVRELVGSHLVEPVPKFSKFIH 462
+ P L + +FPY+V+E+K+ Q + P EW+++L SHLV VPKFS ++
Sbjct: 471 NIPNPLRFLRAGEYSKFPYSVMEIKVINQDNSQMPNYEWIKDLTNSHLVNEVPKFSLYLQ 530
Query: 463 GVASLLND---RVSSIPFWLPQMDVDIRK 488
GVASL + V+ +PFWLP ++ DIRK
Sbjct: 531 GVASLFGEDDKYVNILPFWLPDLETDIRK 559
>YER072w [UO] KOG4580 Component of vacuolar transporter chaperone (Vtc)
involved in vacuole fusion
Length = 129
Score = 92.0 bits (227), Expect = 3e-18
Identities = 43/110 (39%), Positives = 66/110 (59%)
Query: 619 PGKTICVPVRVEPKVYFATERTLLSWISIGLVLGGVSTSFLTYGTPTTMVASTGFFLTAL 678
PGK I +P RVEPKV+FA ERT LSW++ ++LGG+ L +G V++ F A+
Sbjct: 11 PGKKIALPTRVEPKVFFANERTFLSWLNFTVMLGGLGVGLLNFGDKIGRVSAGLFTFVAM 70
Query: 679 FTIWFSTYTYCKRVVNIRMKRSIDYEDKYGPRMICAFLMASILFTFFCNL 728
T+ ++ TY R IR + S Y+D+ GP ++C FL+ +++ F L
Sbjct: 71 GTMIYALVTYHWRAAAIRRRGSGPYDDRLGPTLLCFFLLVAVIINFILRL 120
>SPBC21B10.04c [UO] KOG4580 Component of vacuolar transporter chaperone (Vtc)
involved in vacuole fusion
Length = 122
Score = 92.0 bits (227), Expect = 3e-18
Identities = 45/111 (40%), Positives = 69/111 (61%)
Query: 619 PGKTICVPVRVEPKVYFATERTLLSWISIGLVLGGVSTSFLTYGTPTTMVASTGFFLTAL 678
PGK I +PVRVEPKV+FA ERT LSW+S +VLGG+S L +G +++ F + A+
Sbjct: 11 PGKRIALPVRVEPKVFFANERTFLSWLSFAVVLGGLSVGLLNFGDRIGKISAGLFTIVAI 70
Query: 679 FTIWFSTYTYCKRVVNIRMKRSIDYEDKYGPRMICAFLMASILFTFFCNLV 729
T+ ++ Y R IR + S Y+D+ GP ++C L+A+I+ F ++
Sbjct: 71 GTMGYALGIYHWRASAIRRRGSGPYDDRLGPTILCFVLLAAIITNFVLRML 121
>SPCC1322.14c_2 [UO] KOG4580 Component of vacuolar transporter chaperone (Vtc)
involved in vacuole fusion
Length = 113
Score = 89.7 bits (221), Expect = 1e-17
Identities = 42/103 (40%), Positives = 64/103 (61%), Gaps = 1/103 (0%)
Query: 619 PGKTICVPVRVEPKVYFATERTLLSWISIGLVLGGVSTSFLTYG-TPTTMVASTGFFLTA 677
PGK I VPVRVEPK YFA ERT L ++ +++G + + ++ T + ++ + F L A
Sbjct: 1 PGKRIYVPVRVEPKTYFALERTYLDYLRYSILMGSIGITLFSFAKTRSGILGAASFTLVA 60
Query: 678 LFTIWFSTYTYCKRVVNIRMKRSIDYEDKYGPRMICAFLMASI 720
LF I++ST+ Y R VNI ++ Y+D++GP IC A+I
Sbjct: 61 LFAIFYSTFLYLWRAVNIAKHNAVRYDDRFGPTAICVITFAAI 103
>ECU06g1420i_2 [UO] KOG4580 Component of vacuolar transporter chaperone (Vtc)
involved in vacuole fusion
Length = 114
Score = 84.7 bits (208), Expect = 4e-16
Identities = 43/107 (40%), Positives = 60/107 (55%), Gaps = 1/107 (0%)
Query: 620 GKTICVPVRVEPKVYFATERTLLSWISIGLVLGGVSTSFLTYGTPTTMVASTGFFLTALF 679
GK I +PVRVEPKV+FA ERT LSW+ + LGG+ ++ L G + + A+
Sbjct: 1 GKRISIPVRVEPKVFFANERTFLSWVQFAIFLGGIGSALLGLGDERASFSGLILIIVAII 60
Query: 680 TIWFSTYTYCKRVVNIRMKRSIDYEDKYGPR-MICAFLMASILFTFF 725
++S Y Y R IR + Y+D YGP ++C FL+A L FF
Sbjct: 61 FSFYSLYLYLWRASMIRQRDPGPYDDIYGPAVLVCVFLVAMGLSVFF 107
>At2g26660 [P] KOG1161 Protein involved in vacuolar polyphosphate accumulation
contains SPX domain
Length = 287
Score = 66.2 bits (160), Expect = 2e-10
Identities = 55/216 (25%), Positives = 102/216 (46%), Gaps = 35/216 (16%)
Query: 2 VKFGEHLKRSL---IREYSYYYISYNDLKTELQ----ESLEANNGKWNED---------- 44
+KFG+ L + + E+ ++SY +LK +L+ S+E K +
Sbjct: 1 MKFGKSLSNQIEETLPEWRDKFLSYKELKKKLKLMEPRSVENRPNKRSRSDSNSVDTDPT 60
Query: 45 -----LETQFLESLEIELDKVYTFCKVKHNEVVRRIKQAQEQVSVAVRSLDTNVPVTDLD 99
E F+ LE EL+K +F + E + R+K+ ++QV+ A S + + +
Sbjct: 61 VGMTKEELDFISLLEDELEKFNSFFVEQEEEYIIRLKELKDQVAKAKNSNEEMINI---- 116
Query: 100 FQILEEELSDIIADVHDLAKFARLNYTGLQKIIKKHDKNTNFILKPIFQVRMDAKPFFKE 159
++E+ D ++ L ++ LNYTGL KI+KK+DK T +++ F ++ +PFF
Sbjct: 117 ----KKEIVDFHGEMVLLMNYSALNYTGLAKILKKYDKRTGALIRLPFIQKVLQEPFFTT 172
Query: 160 NYDELVVK-----LSQLYDIVRTRGNPVKGDSAAGG 190
+ VK L +L+ ++R +G+ G
Sbjct: 173 DLLNTFVKECEAMLDRLFPSNKSRNLDEEGEPTTSG 208
>At5g20150 [P] KOG1161 Protein involved in vacuolar polyphosphate accumulation
contains SPX domain
Length = 256
Score = 62.0 bits (149), Expect = 3e-09
Identities = 47/184 (25%), Positives = 91/184 (48%), Gaps = 23/184 (12%)
Query: 2 VKFGEHLKRSL---IREYSYYYISYNDLKTELQESLEANNGKWNEDL------------E 46
+KFG+ L + + E+ ++SY +LK L+ + + L E
Sbjct: 1 MKFGKSLSNQIEQTLPEWQDKFLSYKELKKRLKLIGSKTADRPVKRLRLDEFSVGISKEE 60
Query: 47 TQFLESLEIELDKVYTFCKVKHNEVVRRIKQAQEQVSVAVRSLDTNVPVTDLDFQILEEE 106
F++ LE EL+K F K E + R+K+ +++++ A S++ + + +E
Sbjct: 61 INFIQLLEDELEKFNNFFVEKEEEYIIRLKEFRDRIAKAKDSMEKMIKI--------RKE 112
Query: 107 LSDIIADVHDLAKFARLNYTGLQKIIKKHDKNTNFILKPIFQVRMDAKPFFKENYDELVV 166
+ D ++ L ++ LNYTGL KI+KK+DK T +++ F ++ +PF+ + +V
Sbjct: 113 IVDFHGEMVLLENYSALNYTGLVKILKKYDKRTGDLMRLPFIQKVLQQPFYTTDLLFKLV 172
Query: 167 KLSQ 170
K S+
Sbjct: 173 KESE 176
>At2g45130 [P] KOG1161 Protein involved in vacuolar polyphosphate accumulation
contains SPX domain
Length = 245
Score = 62.0 bits (149), Expect = 3e-09
Identities = 46/191 (24%), Positives = 91/191 (47%), Gaps = 15/191 (7%)
Query: 2 VKFGEHLKRSL---IREYSYYYISYNDLKTELQESLEANNGKWNEDLETQFLESLEIELD 58
+KFG+ +K + + E+ ++ Y +LK + +E+ F+ L E+D
Sbjct: 1 MKFGKRIKEQIQESLPEWRDKFLRYKELKNLISSPAP---------VESIFVGLLNAEID 51
Query: 59 KVYTFCKVKHNEVVRRIKQAQEQVSVAVRSLDTNVPVTDLDFQILEEELSDIIADVHDLA 118
K F + + + K+ Q ++ V N ++ + + +++ + ++ L
Sbjct: 52 KFNAFFVEQEEDFIIHHKELQYRIQRLVEKCGHNDEMSRENISEIRKDIVNFHGEMVLLV 111
Query: 119 KFARLNYTGLQKIIKKHDKNTNFILKPIFQVRMDAKPFFKENYDELVVKLSQLYDIVRTR 178
++ +NYTGL KI+KK+DK T L+ F ++ +PFFK +LV +L + ++
Sbjct: 112 NYSNINYTGLAKILKKYDKRTRGGLRSPFIQKVLHQPFFK---TDLVSRLVREWETTMDA 168
Query: 179 GNPVKGDSAAG 189
+PVK A G
Sbjct: 169 VDPVKVAEAEG 179
>Hs19923272 [U] KOG1162 Predicted small molecule transporter
Length = 696
Score = 53.1 bits (126), Expect = 1e-06
Identities = 45/165 (27%), Positives = 69/165 (41%), Gaps = 29/165 (17%)
Query: 2 VKFGEHLKRSLIREYSYYYISYNDLKTELQE------SLEANNG----KWNEDLETQFLE 51
+KF EHL + E+ YI Y K L S+E + ++ E +F +
Sbjct: 1 MKFAEHLSAHITPEWRKQYIQYEAFKDMLYSAQDQAPSVEVTDEDTVKRYFAKFEEKFFQ 60
Query: 52 SLEIELDKVYTFCKVKHNEVVRRIKQAQEQVSVAVRSLDTNVPVTDLD------FQILEE 105
+ E EL K+ TF K E RR Q ++ ++ + + VT L F + E
Sbjct: 61 TCEKELAKINTFYSEKLAEAQRRFATLQNELQSSLDAQKESTGVTTLRQRRKPVFHLSHE 120
Query: 106 E-------------LSDIIADVHDLAKFARLNYTGLQKIIKKHDK 137
E S+ + L + LN+TG +KI+KKHDK
Sbjct: 121 ERVQHRNIKDLKLAFSEFYLSLILLQNYQNLNFTGFRKILKKHDK 165
>7295413 [U] KOG1162 Predicted small molecule transporter
Length = 671
Score = 52.4 bits (124), Expect = 2e-06
Identities = 41/161 (25%), Positives = 71/161 (43%), Gaps = 27/161 (16%)
Query: 2 VKFGEHLKRSLIREYSYYYISYNDLKTELQESLEANNG----------KWNEDLETQFLE 51
+KF EHL + E+ YI+Y ++K L ++E + ++ + +F
Sbjct: 1 MKFAEHLTAHITPEWRKQYINYEEMKAMLYAAIEQSPSAELVEREMVTRYFAKFDEEFFH 60
Query: 52 SLEIELDKVYTFCKVKHNEVVRRIKQAQEQVSVAV-----RSLDT----------NVPVT 96
+ EL K+ TF K E R+ + +++ A+ + L NVP
Sbjct: 61 YCDKELAKINTFYSEKMAEATRKYGSLRSELTEALEMGHPKKLPAWKRRTPLGKKNVPAR 120
Query: 97 DLDFQILEEELSDIIADVHDLAKFARLNYTGLQKIIKKHDK 137
+ Q L+ S+ + L + LN+TG +KI+KKHDK
Sbjct: 121 KI--QDLKLAFSEFYLGLILLQNYQNLNFTGFRKILKKHDK 159
>7293416 [U] KOG1162 Predicted small molecule transporter
Length = 681
Score = 51.6 bits (122), Expect = 4e-06
Identities = 49/218 (22%), Positives = 89/218 (40%), Gaps = 32/218 (14%)
Query: 2 VKFGEHLKRSLIREYSYYYISYNDLKTELQESLE-ANNGKWNED---------LETQFLE 51
+KF EHL + E+ YI+Y ++K L ++E A + + ED + F
Sbjct: 1 MKFAEHLSAHITPEWRKQYINYEEMKAMLYLAVEEAPSVESVEDDVLKRHFANFDENFFH 60
Query: 52 SLEIELDKVYTFCKVKHNEVVRRIKQAQEQVSVAVRSLDTNVP----------VTDLDFQ 101
+ EL K+ TF K E R+ ++ ++ + + + D +
Sbjct: 61 YCDKELKKINTFYSEKLAEATRKFATLNAELKTSIEESERSAKKSKGHKRHAALPDRKAR 120
Query: 102 ILEEELSDIIADVHDLAKFARLNYTGLQKIIKKHDKNTNFILKPIFQVRMDAKPFFKENY 161
L+ S+ + L + LN+TG +KI+KKHDK +R+D +++ Y
Sbjct: 121 ELKLAFSEFYLSLILLQNYQNLNHTGFRKILKKHDK----------LLRVDTGAKWRQEY 170
Query: 162 DEL--VVKLSQLYDIVRTRGNPVKGDSAAGGKQQNFVR 197
E + +I+ V G+ G +Q+ R
Sbjct: 171 VEASHFFTNKDIDNIINETETTVTGELEGGDRQRAMKR 208
>At5g15330 [P] KOG1161 Protein involved in vacuolar polyphosphate accumulation
contains SPX domain
Length = 387
Score = 50.4 bits (119), Expect = 9e-06
Identities = 32/118 (27%), Positives = 61/118 (51%), Gaps = 2/118 (1%)
Query: 42 NEDLETQFLESLEIELDKVYTFCKVKHNEVVRRIKQAQEQVSVAVRSLDTNVPVTDLDFQ 101
+EDL+ F+ L EL+K F K + V R+++ +E++ ++ +
Sbjct: 147 SEDLQGSFVRILNDELEKFNDFYVDKEEDFVIRLQELKERIEQVKEKNGEFASESEFSEE 206
Query: 102 ILE--EELSDIIADVHDLAKFARLNYTGLQKIIKKHDKNTNFILKPIFQVRMDAKPFF 157
+++ +L I ++ L ++ LN+ GL KI+KK+DK T +L+ F + +PFF
Sbjct: 207 MMDIRRDLVTIHGEMVLLKNYSSLNFAGLVKILKKYDKRTGGLLRLPFTQLVLHQPFF 264
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.320 0.136 0.404
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 42,795,590
Number of Sequences: 60738
Number of extensions: 1833811
Number of successful extensions: 4739
Number of sequences better than 1.0e-05: 17
Number of HSP's better than 0.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 4684
Number of HSP's gapped (non-prelim): 22
length of query: 729
length of database: 30,389,216
effective HSP length: 114
effective length of query: 615
effective length of database: 23,465,084
effective search space: 14431026660
effective search space used: 14431026660
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)