ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI6143 good E KOG2410 Amino acid transport and metabolism Gamma-glutamyltransferase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI6143 2138821 2140563 581
(581 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
At4g29210 [E] KOG2410 Gamma-glutamyltransferase 140 5e-33
CE28151 [E] KOG2410 Gamma-glutamyltransferase 124 4e-28
At4g39640 [E] KOG2410 Gamma-glutamyltransferase 122 1e-27
SPAC664.09 [E] KOG2410 Gamma-glutamyltransferase 114 4e-25
At4g39650 [E] KOG2410 Gamma-glutamyltransferase 112 2e-24
7293291 [E] KOG2410 Gamma-glutamyltransferase 111 3e-24
ECU05g1240 [E] KOG2410 Gamma-glutamyltransferase 108 2e-23
CE18924 [E] KOG2410 Gamma-glutamyltransferase 101 3e-21
SPAC56E4.06c [E] KOG2410 Gamma-glutamyltransferase 99 2e-20
CE17976 [E] KOG2410 Gamma-glutamyltransferase 98 4e-20
7289305 [E] KOG2410 Gamma-glutamyltransferase 96 2e-19
Hs16506295 [E] KOG2410 Gamma-glutamyltransferase 95 3e-19
CE23612 [E] KOG2410 Gamma-glutamyltransferase 94 6e-19
7293479 [E] KOG2410 Gamma-glutamyltransferase 89 1e-17
Hs4758432 [E] KOG2410 Gamma-glutamyltransferase 86 2e-16
7292730 [E] KOG2410 Gamma-glutamyltransferase 81 4e-15
Hs4885271 [E] KOG2410 Gamma-glutamyltransferase 76 1e-13
CE26318 [E] KOG2410 Gamma-glutamyltransferase 67 1e-10
CE13762_2 [E] KOG2410 Gamma-glutamyltransferase 64 8e-10
>At4g29210 [E] KOG2410 Gamma-glutamyltransferase
Length = 637
Score = 140 bits (353), Expect = 5e-33
Identities = 127/498 (25%), Positives = 217/498 (43%), Gaps = 55/498 (11%)
Query: 10 VVYSTQGVVASTQPLASAAGIRILELGGNXXXXXXXXXXXXXXXEPASTGVGGDCFMLHY 69
VV S GVVA+ S G +L GG+ P S+G+GG F++
Sbjct: 75 VVESENGVVAADDARCSEIGASVLRSGGHAVDAAVAITLCVGVVNPMSSGIGGGSFLIVS 134
Query: 70 DESKKKVVGLNGTGRSPKALDIDHIRSLGIEDVRIPLTSIHSVTVPGTIAGWIDAIEKYG 129
+ K + +P A D ++ D S+ VPG IAG +A ++YG
Sbjct: 135 SQKDSKAEAFDMRETAPLAASKDMYKN----DASAKSLGALSMGVPGEIAGLYEAWKRYG 190
Query: 130 SGRVGLDAILAPAIKLCKEGHII---------SEISAYLTGKCWEDLERLNGNDLLKYWA 180
R+ + PAIKL ++G ++ ++++ L + NG L
Sbjct: 191 --RLPWKPLFEPAIKLARDGFVVYPYLGKAISTKVAMILKDPGMRSVFSRNGQVL----- 243
Query: 181 PIDAPLEPPNTGSLVQNRKLAELLQLVADNGKDGFYKGVVAESIIEEMKTRGGLMDMDDL 240
TG N +LA+ L+ +++ G FY G V E +++++K GG++ MDDL
Sbjct: 244 ---------KTGETCYNPELAQSLETISEQGPGAFYNGTVGEKLVKDVKKAGGIITMDDL 294
Query: 241 AAHKSDFVDPIYLDFLEHKIWEIPPNSQGLVVLLALGIIRELDNQKLINLHSMQRNSVEY 300
++K D + +D + + + +PP S G V ++ LD+ NL++ +
Sbjct: 295 RSYKVRVTDAMSVDVMGYTVHGMPPPSGGTVGFSM--VMNILDSYS--NLYTASGRELG- 349
Query: 301 LHMLIECLKLAFYDSDEYVSDPNCQEADILHRLLSKDYLKSRAKLFSPSGIIDSSVIKHG 360
LH LIE +K F + + ++++LSK + + K I D++
Sbjct: 350 LHRLIEAMKHMFAARMDLGDPEFVNVTNSMNQMLSKAHAEEIQK-----RIFDNTTFPPE 404
Query: 361 VPNEDFNQ---SDTVYFTVSDPYGNVTSFINSLYDGFGSCIV-PRTFGGFALQNRGANFN 416
++Q T +F V D N S +++ FG+ ++ P T G L N +F+
Sbjct: 405 YYMNRWSQLRDQGTSHFCVVDADRNSVSMTSTVNYRFGAGVLSPST--GIVLNNEMDDFS 462
Query: 417 ---------LTPGTKNSLEPSKRPYHTIIPSIITSNDESTVYGMGNMGGFMQPSGHVQHF 467
L P N +EP+KRP ++ P +IT + E V +G GG +Q F
Sbjct: 463 TPTEITPDMLPPAPTNFIEPNKRPLSSMTPLVITKDGE-FVAALGGAGGMHIIPAVLQVF 521
Query: 468 LNLILFGLNPQESLDSPR 485
LN + + P+E+++S R
Sbjct: 522 LNCFVLNMKPKEAVESAR 539
>CE28151 [E] KOG2410 Gamma-glutamyltransferase
Length = 607
Score = 124 bits (311), Expect = 4e-28
Identities = 126/499 (25%), Positives = 209/499 (41%), Gaps = 47/499 (9%)
Query: 8 RSVVYSTQGVVASTQPLASAAGIRILELGGNXXXXXXXXXXXXXXXEPASTGVGGDCFML 67
+S ++ VA ++ A A I++ GGN P +TG+GG F++
Sbjct: 66 KSAIFKNAAAVADSRFCAEIARNVIIQ-GGNAVDAAIAATFCNGVVLPYATGIGGGDFIV 124
Query: 68 HYDESKKKVVGLNGTGRSPKALDIDHIRSLGIEDVRIPLTSIHSVTVPGTIAGWIDAIEK 127
Y + +KK V LN +P + + D S+ +PG + G A +K
Sbjct: 125 IYLKEEKKCVFLNSRETAPSLAT----EKMYVHDKDSAQFGYQSIGIPGELHGLWTAYQK 180
Query: 128 YGSGRVGLDAILAPAIKLCKEGHIISEISAYLTG----KCWEDLERLNGNDLLKYWAPID 183
YGS + ++ PA +L K + + Y K ++E L K+
Sbjct: 181 YGSKVIPWSDLVMPAAQLAKGFPMHKAMHDYFDRISKYKERPEIEALRNLYTSKFTG--- 237
Query: 184 APLEPPNTGSLVQNRKLAELLQLVADNGKDG---FYKGVVAESIIEEMKTRGGLMDMDDL 240
E G +V N LA+ L+L+A N +D FY G +A+ II EM GG++ +DDL
Sbjct: 238 ---EFYKVGEIVANYPLAKFLRLIA-NSQDPVQLFYNGSIADGIIREMLANGGIITIDDL 293
Query: 241 AAHKSDFVDPIYLDFLEHKIWEIPPNSQGLVVLLALGIIRELDNQKLINLHSMQRNSVEY 300
+++ ++ +Y D +++I PP S + I+ L K N E+
Sbjct: 294 RNYRTHVMETLYADLGKYRICGPPPPSSWAITQAIPRIVARLYRDK------KMFNDAEF 347
Query: 301 LHMLIECLKLAFYDS---DEYVSDPNCQEADILHRLLSKDYLKSRAKLFSPSGIIDSSVI 357
H LIE KLA+ +Y+ P + I L ++K +K S +
Sbjct: 348 YHTLIEAEKLAYGQRGQLGDYLFSP--ESMQIARNLTENSFIKYLSKRLKDKSQDVSYYV 405
Query: 358 KHGVPNEDFNQSDTVYFTVSDPYGNVTSFINSLYDGFGSCIVPRTFGGFALQNRGANFNL 417
G D S T +V D GN S +++ FGS ++ + GF N+ +F+
Sbjct: 406 TSGPAIMD---SGTSQISVVDDDGNAVSLTSTINTAFGSKMLSKY--GFIYNNQMDDFS- 459
Query: 418 TPGTKNS----------LEPSKRPYHTIIPSIITSNDESTVYGM-GNMGGFMQPSGHVQH 466
TPG +N ++P +RP ++ P+I+ V + G GG S Q
Sbjct: 460 TPGFQNHWGFEPTAANYIQPGRRPMSSMSPTIVFDVSSGNVKMVTGGTGGSKIISAVAQT 519
Query: 467 FLNLILFGLNPQESLDSPR 485
+ +L G + E ++ PR
Sbjct: 520 LIRGLLMGQSAAEIVEMPR 538
>At4g39640 [E] KOG2410 Gamma-glutamyltransferase
Length = 577
Score = 122 bits (306), Expect = 1e-27
Identities = 143/592 (24%), Positives = 249/592 (41%), Gaps = 67/592 (11%)
Query: 7 RRSVVYSTQGVVASTQPLASAAGIRILELGGNXXXXXXXXXXXXXXXEPASTGVGGDCFM 66
R+ + ++G VA+ S G+R+L GGN PAS+G+GG F
Sbjct: 25 RQQSIVKSRGAVATDDGRCSVIGMRVLREGGNAIDASVAAALCLGVVSPASSGIGGGAFT 84
Query: 67 LHYDESKKKVVGLNGTGRSPKALDIDHIRSLGIEDVRIPLTSIHSVTVPGTIAGWIDAIE 126
+ K++ + +A ++ + ++ +V + SV VPG +AG A +
Sbjct: 85 VVKIAGGKEIAYDSRETAPLRATEVKRVLNMYGGNVDLKKKGALSVGVPGEVAGLFTAWK 144
Query: 127 KYGSGRVGLDAILAPAIKLCKEGHIISEISAYLTGKCWEDLERLNG-NDLLKYWAPIDAP 185
++G ++ ++ PA KL EG IS+ D+ G +DL + P
Sbjct: 145 QHG--KLPWKRLVTPAEKLA-EGFKISKYLYMQMNATRSDILADKGLSDLFVSNGELKKP 201
Query: 186 LEPPNTGSLVQNRKLAELLQLVADNGKDGFYKGVVAESIIEEMKTRGGLMDMDDLAAHKS 245
G++ N KLA L+L+ + G FY G V ++ ++K GG++ + DL +++
Sbjct: 202 ------GTICHNPKLALTLKLIGEYGPKAFYNGTVGVNLARDIKKSGGIITLKDLQSYRV 255
Query: 246 DFVDPIYLDFLEHKIWEI-PPNSQGLVVLLALGIIRELDNQKLINLHSMQRNSVEYLHML 304
+P+ D L +++ + PP+S G ++L L I+ + + + +H L
Sbjct: 256 KIKEPLSADILGYRVLGMPPPSSGGAAMMLVLNILSQYGIPSGV-------SGPLGVHRL 308
Query: 305 IECLKLAFYD----SDEYVSDPNCQEADILHRLLSKDYLKSR---AKLFSPS--GIIDSS 355
IE LK AF D +D +D+L +KD LKS+ K F P G + +
Sbjct: 309 IEALKHAFAVRMNLGDPDFTDVTKVVSDMLSPKFAKD-LKSKINDQKTFDPKYYGGMWNQ 367
Query: 356 VIKHGVPNEDFNQSDTVYFTVSDPYGNVTSFINSLYDGFGSCIV-PRTFGGFALQNRGAN 414
+ HG T + ++ D N S +++ FG+ ++ P T G L N +
Sbjct: 368 IDDHG----------TSHLSIIDRERNAVSMTSTINGYFGALMLSPST--GIVLNNEMDD 415
Query: 415 FNL-----------TPGTKNSLEPSKRPYHTIIPSIITSNDESTVYGMGNMGGFMQPSGH 463
F++ P N + P KRP ++ P+I+ D +G GG +G
Sbjct: 416 FSIPMKSNGNLDVPPPAPANFIRPGKRPLSSMSPTIVL-KDGKVKAAVGASGGANIIAGT 474
Query: 464 VQHFLNLILFGLNPQESLDSPRCCLSPHPKYSHLDRGRGSSGPVNTPVSLIQLEEDIPED 523
+ +LN ++P S+ +PR Y L R S ++ +IP+
Sbjct: 475 TEVYLNHFFLKMDPLSSVLAPRI-------YHQLIPNRAS---YENWTTVFNDHFEIPKA 524
Query: 524 VFDGLVKLGHEVEYVRGLSRSIFGRGQIIKRTKNNETNTWLYAAGSDKRGDG 575
L K GH + + G + + F I++ + N A SD R G
Sbjct: 525 TRVVLEKKGHVLSPIAGGTIAQF----IVQESGENSGGRSELVAVSDPRKGG 572
>SPAC664.09 [E] KOG2410 Gamma-glutamyltransferase
Length = 630
Score = 114 bits (285), Expect = 4e-25
Identities = 129/553 (23%), Positives = 219/553 (39%), Gaps = 66/553 (11%)
Query: 6 SRRSVVYSTQGVVASTQPLASAAGIRILELGGNXXXXXXXXXXXXXXXEPASTGVGGDCF 65
S+R VV GVVA+ + S G+ IL+ GGN S+G+GG F
Sbjct: 90 SQRVVVEGKNGVVATEEETCSQIGVGILKAGGNAVDAAIASGICIGAVNSFSSGIGGGGF 149
Query: 66 ML-HYDESKKKVVGLNGTGRSPKALDIDHIRSLGIEDVRIPLTSIHSVTVPGTIAGWIDA 124
ML + + T + + ++ H S + SV VPG IAG+ A
Sbjct: 150 MLIRHPNGTAHSLNFRETAPAGASKNMFHGNST------LSQVGGLSVAVPGEIAGYERA 203
Query: 125 IEKYGSGRVGLDAILAPAIKLCKEGHIIS----------EISAYLTGKCWEDLERLNGND 174
+ YGS + + P I+L ++G + E S + T W
Sbjct: 204 WKMYGS--LPWHKLFEPTIRLMRDGMPMPKELASRIRRPEFSYFKTHPDWS--------- 252
Query: 175 LLKYWAPIDAPLEPPNTGSLVQNRKLAELLQLVADNGKDGFYKGVVAESIIEEMKTRGGL 234
K +AP L + G LA L+ +A G + FY G +AE +++ ++ +GG+
Sbjct: 253 --KIFAPEGVFL---HVGEKFYRPALASTLEEIAKFGPEVFYTGKIAERLVKFVQQQGGI 307
Query: 235 MDMDDLAAHKSDFVDPIYLDFLEHKIWEIPPNSQGLVVLLALGIIRELDNQKLINLHSMQ 294
+ M+D+A +PIY +F + ++ G ++L L ++ ++D + ++ +
Sbjct: 308 LTMEDMANFSVVVEEPIYGNFYDREVITCGSPCSGEALILGLNVLSKVDLSEGTSILGCE 367
Query: 295 RNSVEYLHMLIECLKLAFYDSDEYVSDPNCQEADILHRLLSKDYLKSRAKLFSPSGIIDS 354
+ +H LIE +K D + +LLS +Y S D
Sbjct: 368 MTDIG-VHHLIETMKWMSAGRTVLADPTFYNNTDHVEQLLSLEYADEIRNNISNERTFD- 425
Query: 355 SVIKHGVPNEDF-NQSDTVYFTVSDPYGNVTSFINSLYDGFGSCIV-PRT-------FGG 405
H DF N T + +V D S+ FGS ++ P T
Sbjct: 426 --FTHYKAEYDFPNDHGTTHLSVIDKDNMAVGLTASINLMFGSQLLEPETGIILNDHMDD 483
Query: 406 FALQNRGANFNLTPGTKNSLEPSKRPYHTIIPSIITSNDESTVYGMGNMGGFMQPSGHVQ 465
FA F L+P N + P KRP + +P+I+ N E + +G GG + +
Sbjct: 484 FASPGIVNAFGLSPSPYNFIAPGKRPQSSAVPTILVYNGEVEMV-LGGSGGSRIVTAVLD 542
Query: 466 HFLNLILFGLNPQESLDSPRCCLSPHPKYSHLDRGRGSSGPVNTPVSLIQLEEDIPEDVF 525
+ +G + ES++SPR + H +++ ++E + +V
Sbjct: 543 TIIKKYKWGKSLLESVESPR--------FHH-----------QLMPNIVYIDETVEIEVL 583
Query: 526 DGLVKLGHEVEYV 538
L K GH V+ +
Sbjct: 584 RALEKFGHIVDLI 596
>At4g39650 [E] KOG2410 Gamma-glutamyltransferase
Length = 574
Score = 112 bits (279), Expect = 2e-24
Identities = 118/496 (23%), Positives = 207/496 (40%), Gaps = 52/496 (10%)
Query: 11 VYSTQGVVASTQPLASAAGIRILELGGNXXXXXXXXXXXXXXXEPASTGVGGDCFMLHYD 70
+ + G VA+ SA G +L GGN PAS+G+GG F +
Sbjct: 29 IVAYHGAVATDDGRCSAIGTNVLRQGGNAIDASVAAALCLGVVSPASSGIGGGAFTMI-- 86
Query: 71 ESKKKVVGLNGTGRSPKALDIDHIRSLGIEDVRIPLTSIHSVTVPGTIAGWIDAIEKYGS 130
K G S + + + ++ SV VPG +AG A ++G
Sbjct: 87 ---KLANGTEVAYDSRETAPLSATEDMYGDNPERKKKGSLSVGVPGEVAGLYTAWTQHG- 142
Query: 131 GRVGLDAILAPAIKLCKEGHIISEISAYLTGKCWEDLERLNGNDLLKYWAPIDAPLEPPN 190
++ ++ PA KL EG +IS YL + + + L + L+ P
Sbjct: 143 -KLPWKQLVEPAEKLAAEGF---KISKYLYMQMNATRSDILADKGLSELFVSNGELKKP- 197
Query: 191 TGSLVQNRKLAELLQLVADNGKDGFYKGVVAESIIEEMKTRGGLMDMDDLAAHKSDFVDP 250
G++ +N KLA+ L +A+ G FY G V +++ +++ GG++ + DL + +P
Sbjct: 198 -GAICRNPKLADTLSQIAEYGPKAFYNGTVGFNLVSDIQKAGGIITLKDLQNYNVKVKEP 256
Query: 251 IYLDFLEHKIWEI-PPNSQGLVVLLALGIIRELDNQKLINLHSMQRNSVEYLHMLIECLK 309
+ + L +++ + PP+S G ++L L I+ + + + +H L+E LK
Sbjct: 257 LSTEILGYRLLGMPPPSSGGPAMMLILNILAQYGIPSGV-------SGPLGVHRLVEALK 309
Query: 310 LAF-----YDSDEYVSDPNCQEADILHRLLSKDYLKSR---AKLFSPSGIIDSSVIKHGV 361
AF ++V + AD+L ++D LKS+ K F P +G
Sbjct: 310 HAFAVRMNLGDPDFVPEVTNVVADMLSPKFAQD-LKSKINDEKTFDPK--------YYGG 360
Query: 362 PNEDFNQSDTVYFTVSDPYGNVTSFINSLYDGFGSCIV-PRTFGGFALQNRGANFNL--- 417
T + ++ D N S +++ FG+ ++ P T G L N +F++
Sbjct: 361 KWGQIKDHGTSHLSIIDSERNAVSMTSTINGYFGAIMLSPST--GIVLNNEMDDFSIPTK 418
Query: 418 --------TPGTKNSLEPSKRPYHTIIPSIITSNDESTVYGMGNMGGFMQPSGHVQHFLN 469
P N + P KRP ++ P+I+ D +G GG +G Q +LN
Sbjct: 419 SGGDPDVPPPAPANFIRPGKRPLSSMTPTIVL-KDGKVKAALGASGGMYIIAGTTQVYLN 477
Query: 470 LILFGLNPQESLDSPR 485
++P S+ +PR
Sbjct: 478 HFFLNMDPLSSVVAPR 493
>7293291 [E] KOG2410 Gamma-glutamyltransferase
Length = 777
Score = 111 bits (278), Expect = 3e-24
Identities = 113/484 (23%), Positives = 208/484 (42%), Gaps = 33/484 (6%)
Query: 16 GVVASTQPLASAAGIRILELGGNXXXXXXXXXXXXXXXEPASTGVGGDCFMLHYDESKKK 75
G V+S S G IL+ G+ S G+GG M Y+ ++
Sbjct: 245 GAVSSDNLECSKIGSGILQKNGSAVDAAIAALLCNGLLTLQSMGIGGGHLMNVYNRKERH 304
Query: 76 VVGLNGTGRSPKALDIDHIRSLGIEDVRIPLTSIHSVTVPGTIAGWIDAIEKYGSGRVGL 135
++ +P D + PL S+ VPG + G+ A +K+G ++
Sbjct: 305 ATAIDAREVAPYEATEDMFAQQPENSDKGPL----SIAVPGEVMGYHVAHQKFG--QLPW 358
Query: 136 DAILAPAIKLCKEGHIISEISAYLTGKCWEDLERLNGNDLLKYWAPIDAPLEPPNTGSLV 195
++AP+++LC++G+ +S+ D+ + +Y ++A P+ V
Sbjct: 359 AELVAPSLELCEKGYHVSQHMERAL-----DIALPYIKEHEQYQIYLNAETGKPHVAGTV 413
Query: 196 QN--RKLAELLQLVADNGKDGFYKGVVAESIIEEMKTRGGLMDMDDLAAHKSDFVDPIYL 253
+ L + +L+A+NG Y G +A+ + E+++ G ++ DDL ++++D ++ I +
Sbjct: 414 VKPPKNLCKTYKLLAENGPMDMYNGTIAKLLAEDLQDMGSIILADDLESYEADVINSITM 473
Query: 254 DFLEHKIWEIPPNSQGLVVLLALGIIR--ELDNQKLINLHSMQRNSVEYLHMLIECLKLA 311
D + ++ +PP S G VV L I++ Q L S + +H E +K A
Sbjct: 474 DLGDDTLYVVPPVSSGSVVAHVLAILQGYNFTAQDL----STEELKARTIHRFAEAMKFA 529
Query: 312 FYDSDEYVSDPNCQEADILHRLLSKDY-LKSRAKLFSPSGIIDSSVIKHGVPNEDFNQSD 370
F E +++ RL S D+ ++RAK+ + D+ +G D
Sbjct: 530 FAQRPELGDMHFIDARELVSRLNSPDFGDQNRAKINDSHVLPDAQA--YGANFAAIEDLD 587
Query: 371 -TVYFTVSDPYGNVTSFINSLYDGFGSCIV-PRT-------FGGFALQNRGANFNLTPGT 421
T V P G+ S +S+ FGS ++ PRT FA++N F L
Sbjct: 588 GTSNLVVLAPNGDAVSVTSSINSYFGSGLIGPRTGIVLNNGMNDFAVKNN--IFALPQSQ 645
Query: 422 KNSLEPSKRPYHTIIPSIITSNDESTVYGMGNMGGFMQPSGHVQHFLNLILFGLNPQESL 481
N +E KR + P ++ D + +G GG V+ N++ FG + ++++
Sbjct: 646 SNKIEAHKRAMSSQSPILLADKDGNMKMVIGAAGGSKIIPAVVEVAANVLWFGKDLRQAV 705
Query: 482 DSPR 485
D+PR
Sbjct: 706 DAPR 709
>ECU05g1240 [E] KOG2410 Gamma-glutamyltransferase
Length = 658
Score = 108 bits (270), Expect = 2e-23
Identities = 137/584 (23%), Positives = 243/584 (41%), Gaps = 74/584 (12%)
Query: 11 VYSTQGVVASTQPLASAAGIRILELGGNXXXXXXXXXXXXXXXEPASTGVGGDCFMLHYD 70
VYS G ++ PL S G++ L GGN S+G+GG FML
Sbjct: 128 VYSN-GACSTEVPLCSRIGVKKLVEGGNAMDAAIASAICVGIINSFSSGIGGGGFMLIKG 186
Query: 71 ESKKKVVGLNGTGR-SPKALDIDHIRSLGIEDVRIPLTSIHSVTVPGTIAGWIDAIEKYG 129
+ +PK L D + G T S+ VPG I G +A +KYG
Sbjct: 187 PGTSNAFDMIDFREVAPKNLSADKLSEAGG-------TGALSIGVPGEIYGLYEAHKKYG 239
Query: 130 SGRVGLDAILAPAIKLCKEGHIISEISAYLTGKCWEDLERLNGNDLLKYWAPIDAPLEPP 189
R+ + I++ + +++ ++R+N LK + D L
Sbjct: 240 --RLPWRDLFPENIEVSRGFPASNQL-----------VKRINK---LKDYIISDPGLREI 283
Query: 190 NT--------GSLVQNRKLAELLQLVADNGKDGFYKGVVAESIIEEMKTRGGLMDMDDLA 241
T G V A L+++ D+ + FY G +A+ +++ ++ RGG++D DL
Sbjct: 284 YTRNGELLREGETVVRENYARTLEIIMDH-PESFYMGHLADLVVKAVRERGGILDKKDLE 342
Query: 242 AHKSDFVDPIYLDFLEHKIWEIPPNSQGLVVLLALGIIRELDNQKLINLHSMQRNSVEYL 301
+++ + D + + ++K++ + GL+VL AL I + D +KL S++ ++
Sbjct: 343 EYRAVYRDVLEGRYRDYKVYTTGLPTSGLLVLKALNIFEKYDLRKL-KADSLKSGGFNHI 401
Query: 302 HMLIECLKLAFYDSDEYVSDPNCQEA--DILHRLLSKDYLKSRAKLFSPSGIIDSSVIKH 359
H+LIE K A E ++DP +I++ +SKD + + ++D+ ++
Sbjct: 402 HLLIEVFKFAMAGRGE-LADPAFLPGWEEIVYETVSKDAAEEAYHKINLGRVLDTK--EY 458
Query: 360 GVPNEDFNQSDTVYFTVSDPYGNVTSFINSLYDGFGSCIV-PRTFGGFALQNRGANFNLT 418
G+ + T + D V +++ FG+ + PRT G N ++F +
Sbjct: 459 GMKRKGVEDHGTTHINAIDKDDMVVLLTSTVNLEFGAKFMDPRT--GIIFNNTMSDFYIP 516
Query: 419 -PGT-----KNSLEPSKRPYHTIIPSIITSNDESTVYGMGNMGGFMQPSGHVQHFLNLIL 472
P + N++E KRP+ +I P ++ DE + +G GG P+ + +L
Sbjct: 517 YPNSAQEKHANAVEGGKRPFSSIAPVVLLKEDE--LLALGAAGGIRIPTSIMSTIFHLSA 574
Query: 473 FGLNPQESLDSPRCCLSPHPKYSHLDRGRGSSGPVNTPVSLIQLEEDIPEDVFDGLVKLG 532
G N E++ R P + +E +IP+D+ L G
Sbjct: 575 -GENLWEAITETRIHNQLFP-------------------DITFVEYNIPKDLEKYLTSTG 614
Query: 533 HEVEYVRGLSRSIFGRGQIIKRTKNNETNTWLYAAGSDKRGDGA 576
H VE R L ++F Q I K N ++A ++G A
Sbjct: 615 HRVE--RSLQNTVFTSVQGILSRKVG-GNKVIHAVSDPRKGGEA 655
>CE18924 [E] KOG2410 Gamma-glutamyltransferase
Length = 589
Score = 101 bits (252), Expect = 3e-21
Identities = 113/510 (22%), Positives = 206/510 (40%), Gaps = 39/510 (7%)
Query: 15 QGVVASTQPLASAAGIRILELGGNXXXXXXXXXXXXXXXEPASTGVGGDCFMLHYDESKK 74
+ + S S G IL GGN P S+G+GG M ++D+
Sbjct: 37 KAALTSDNAACSKIGGEILRKGGNSIDASIASMFCLGVVNPQSSGIGGGFLMTYFDQKSG 96
Query: 75 KVVGLNGTGRSPKALDIDHIRSLGIEDVRIPLTSIHSVTVPGTIAGWIDAIEKYGSGRVG 134
++ +P A R + + D + PG IAG+ +K+GSG+V
Sbjct: 97 DCYSIDARETAPAAAS----RDMFLNDSDGSKYGFKAAGTPGEIAGYWHIFKKFGSGKVT 152
Query: 135 LDAILAPAIKLCKEGHIISEISAYLTGKCWEDLERL---------NGNDLLKYWAPIDAP 185
++ P++KL +EGH +S A + K E RL + ++W +
Sbjct: 153 WKELVQPSVKLAREGHPVSPYLATVM-KVKERHFRLFPSVKASSIKLSMFYRHWINPETN 211
Query: 186 LEPPNTGSLVQNRKLAELLQLVAD--NGKDGFYKGVVAESIIEEMKTRGGLMDMDDLAAH 243
+ +G L++ KLA+ L+ + + N FY G +A+++ +E + GGL+ DLA +
Sbjct: 212 -DTYQSGDLLKRPKLAKTLERLGNSPNPVQLFYHGEMAKTLAKEFQEGGGLITEQDLANY 270
Query: 244 K-SDFVDPIYLDFLEHKIWEI---PPNSQGLVVLLALGIIRELDNQKLINLHSMQRNSVE 299
K ++V+ D + PP+S G+ L+ + + +++ N +
Sbjct: 271 KVREYVNSNSNDHFRGTLTMCGGPPPSSFGVTQLIVSAMSKLFPEGHKDDIY----NDPK 326
Query: 300 YLHMLIECLKLAFYDSDEYVSDPNCQEA--DILHRLLSKDYLKSRAKLFSPSGIIDSSVI 357
LH IE +K A Y + D + + ++ L + +Y + + SS
Sbjct: 327 VLHKYIEAMKFA-YAQRTLLGDHDFVKGALELSKNLTTPEYTQWVIDRMTDKA--QSSKN 383
Query: 358 KHGVPNEDFNQSDTVYFTVSDPYGNVTSFINSLYDGFGSCIVPRTFG--------GFALQ 409
G+ T + + D YGN S ++ FG+ + +G F+
Sbjct: 384 YGGIAQYVPPDHGTSHVSAMDQYGNGVSATTTINRWFGAAVESSEYGILWNDEMDDFSTP 443
Query: 410 NRGANFNLTPGTKNSLEPSKRPYHTIIPSIITSNDESTV-YGMGNMGGFMQPSGHVQHFL 468
F P N +EP KRP ++ P +I + V +G GG S + +
Sbjct: 444 GMENGFGFAPSETNFIEPGKRPMSSMSPMVIFDHVTKKVRMVIGGSGGSKIISALAKSIV 503
Query: 469 NLILFGLNPQESLDSPRCCLSPHPKYSHLD 498
++F + ++++D+P P + LD
Sbjct: 504 RSLIFHDSIKKAIDAPMIHNQFTPDITQLD 533
>SPAC56E4.06c [E] KOG2410 Gamma-glutamyltransferase
Length = 611
Score = 99.0 bits (245), Expect = 2e-20
Identities = 120/509 (23%), Positives = 219/509 (42%), Gaps = 69/509 (13%)
Query: 11 VYSTQGVVASTQPLASAAGIRILELGGNXXXXXXXXXXXXXXXEPASTGVGGDCFML--H 68
V +G VAS P+ S G+ +L GGN S+G+GG FML H
Sbjct: 77 VRGRRGAVASEVPVCSDIGVSMLADGGNAVDAAIASTFCIGVVNFFSSGIGGGGFMLIKH 136
Query: 69 YDESKKKVVGLNGTGRSPKALDIDHIRSLGIEDVRIPLTSIHSVTVPGTIAGWIDAIEKY 128
+E+ + + T R ++ + + ++ + S+ +PG +AG +A + +
Sbjct: 137 PNETAQSL-----TFREIAPGNVS--KHMFDKNPMLAQVGPLSIAIPGELAGLYEAWKSH 189
Query: 129 GSGRVGLDAILAPAIKLCKEGHIISEISAYLTGKCWEDLERLNGNDLLKYWAPIDAPLEP 188
G + +L P +KL +EG ++ + L+ LLK PI P+
Sbjct: 190 GL--LDWSKLLEPNVKLAREGFPVTRAMERV-------LKLPEMAHLLK--DPIWQPILM 238
Query: 189 PNTGSLVQNRKL-----AELLQLVADNGKDGFYKGVVAESIIEEMKTRGGLMDMDDLAAH 243
PN L K+ A+ L+++A+ G + FY+G + S+++ ++ GG++ ++D +
Sbjct: 239 PNGKVLRAGDKMFRPAYAKTLEIIANKGIEPFYRGELTNSMVKFIQDNGGIVTVEDFGNY 298
Query: 244 KSDFVDPIYLDFLEHKIWEIPPNSQGLVVLLALGIIRELDNQKLINLHSMQRNSVEYLHM 303
+ F D ++ + H ++ + G ++ L I LD L N S+ + LH+
Sbjct: 299 STVFADALHTSYRGHDVYTCTLPTSGPALIEGLNI---LDGYPL-NTPSLA--FPKRLHL 352
Query: 304 LIECLKLAFYDSDEYVSDPN---CQEADILHRLLSKDYLKSRAKLFSPSGIIDSSVIKHG 360
+E +K ++ DP+ D++ +LLSK++ S I ++ +
Sbjct: 353 EVEAMKWLSAGRTQF-GDPDFLPLDHLDVVSKLLSKEF---------ASQIRNNISLSKT 402
Query: 361 VPNEDFNQS-------DTVYFTVSDPYG---NVTSFINSLYDGFGSCIVPRTFG------ 404
P E +N S T + + D ++TS +N L FGS ++ G
Sbjct: 403 YPWEHYNPSYDLPISHGTTHVSTVDSNNLAVSITSTVNLL---FGSQLMDPVTGVVFNDQ 459
Query: 405 --GFALQNRGANFNLTPGTKNSLEPSKRPYHTIIPSIITSNDESTVYGMGNMGGFMQPSG 462
F++ FNL+P N +EP KRP + P+I+T + +G GG S
Sbjct: 460 MDDFSIPGASNAFNLSPSPWNFIEPFKRPQSSSAPTILTDINGDFEMALGASGG----SR 515
Query: 463 HVQHFLNLILFGLNPQESLDSPRCCLSPH 491
V L+ I+ ++ ++S PH
Sbjct: 516 IVTAVLDSIIKRIDMDYDIESMVASARPH 544
>CE17976 [E] KOG2410 Gamma-glutamyltransferase
Length = 633
Score = 97.8 bits (242), Expect = 4e-20
Identities = 109/488 (22%), Positives = 203/488 (41%), Gaps = 44/488 (9%)
Query: 15 QGVVASTQPLASAAGIRILELGGNXXXXXXXXXXXXXXXEPASTGVGGDCFMLHYDESKK 74
+ V S L S G +L GGN P S+G+GG M Y+ S
Sbjct: 104 KAAVTSDHGLCSEIGRDVLIEGGNAVDAMIASLLCIGTVNPQSSGIGGGFVMTLYNASTG 163
Query: 75 KVVGLNGTGRSPKALDIDHIRSLGIEDVRIPLTSIHSVTVPGTIAGWIDAIEKYGSGRVG 134
+N +P A ++ +++ + + S+ P + G+ YGSG+V
Sbjct: 164 MCQTINARETAPAAAT----ETMFVDNPKESVMGYKSIATPSELHGFWTVFNMYGSGKVS 219
Query: 135 LDAILAPAIKLCKEGHIISEISAYLTGKCWEDLERLNGNDLLKYWAPIDAPLEPPNTGSL 194
+ P+I L +G +S S K D+ +N Y G +
Sbjct: 220 WARLFQPSITLAHDGFPVS--SNLAMRKFSRDIF-VNPKTNRVY-----------EEGDI 265
Query: 195 VQNRKLAELLQLVAD--NGKDGFYKGVVAESIIEEMKTRGGLMDMDDLAAHKSDFVD-PI 251
++ ++LA L+A+ + + FYKG +A++I E+ GG ++ DLA++++ D P+
Sbjct: 266 LKRQRLASTYALLANATDPVELFYKGGMAQTIAGEITDNGGFVNESDLASYETTIDDAPL 325
Query: 252 YLDFL--EHKIWEIPPNSQGLVVLLALGIIRELDNQKLINLHSMQRNSVEYLHMLIECLK 309
L ++++ PP S ++ + ++ + ++L + H LIE K
Sbjct: 326 LSTHLPGDYEMCGPPPPSSFVITQNIIQVMAQYYKDGQVDL-----DDPLVYHRLIEAEK 380
Query: 310 LAFYDSDEYVSDPNCQEA--DILHRLLSKDYLKSRAKLFSPSGIIDSSVIKHGVPNEDF- 366
A Y + D E+ ++ +++++Y K A L + ++ +G +D
Sbjct: 381 FA-YAQRTKLGDVKFVESAKTLVDEMMTEEYTKKIASLIKDTA---QTLDYYGGEKKDMA 436
Query: 367 NQSDTVYFTVSDPYGNVTSFINSLYDGFGSCIVPRTFG--------GFALQNRGANFNLT 418
T + ++ D +GN S +++ GS T G F+ +F
Sbjct: 437 PDHGTSHVSIIDSHGNAVSCTSTVNQILGSMRASPTLGIVWNDQMDDFSTPGMKNSFGYA 496
Query: 419 PGTKNSLEPSKRPYHTIIPSIITSNDESTVYGM-GNMGGFMQPSGHVQHFLNLILFGLNP 477
P N ++P KRP ++ P II + +E+ V + G GG S Q + +LF
Sbjct: 497 PSETNFIQPGKRPMSSMSPMIIYNKNENRVEMVTGASGGSYIISATAQTVIRTLLFNQTV 556
Query: 478 QESLDSPR 485
+ ++D+PR
Sbjct: 557 KAAVDAPR 564
>7289305 [E] KOG2410 Gamma-glutamyltransferase
Length = 571
Score = 95.5 bits (236), Expect = 2e-19
Identities = 119/539 (22%), Positives = 208/539 (38%), Gaps = 63/539 (11%)
Query: 16 GVVASTQPLASAAGIRILELGGNXXXXXXXXXXXXXXXEPASTGVGGDCFMLHYDESKKK 75
G VAS + G IL++GG+ P S GVGG Y +
Sbjct: 40 GAVASNGVGCAEVGGSILDIGGSAADAAIATMLCEGVMLPHSLGVGGGFVATIYSRETEF 99
Query: 76 VVGLNGTGRSPKALDIDHIRSLGIEDVRIPLTSIHSVTVPGTIAGWIDAIEKYGSGRVGL 135
L +P A D V+ +T S VP I G+ + +KYG R+
Sbjct: 100 SEVLIARETAPAAATQDMF-------VKTEITGALSCAVPAEIYGYSELHDKYG--RLPW 150
Query: 136 DAILAPAIKLCKEGHIISEISAYLTGKCWEDLERLNGNDLLKYWAPIDAPLEPPNTGSLV 195
+ P I LC+ G ++S YL+G + ER+ + E G ++
Sbjct: 151 KTLFQPTIDLCRRGILVSR---YLSGVLQREEERIRNEPSMAEIFINPKTDEVYKQGEVM 207
Query: 196 QNRKLAELLQLVADNGKDGFYKGV-VAESIIEEMKTRGGLMDMDDLAAHKSDFVDPIYLD 254
LAE L+++AD G Y G V ++E+++ GG++ +DL ++ + P++
Sbjct: 208 YRHTLAETLEIIADEGAKAIYGGGRVGRKLVEDIQAMGGIVTEEDLQSYNVRWEMPLHSH 267
Query: 255 FLE-HKIWEIPPNSQGLVVLLALGIIRELDNQKLINLHSMQRNSVEYLHMLIECLKLAF- 312
F +K+ + G V+ L ++ L N+ +Y LIE K A+
Sbjct: 268 FSGGYKLITSTLPTSGAVLTFMLNVMEPLYTS----------NTDKYWQRLIETFKHAYG 317
Query: 313 --YDSDEYVSDPNCQEADILHRLLSKDYLKSRAKLFSPSGII-DSSVIKHGVPNEDFNQS 369
+ + +P+ QE + L+ + KL D S NE+
Sbjct: 318 HRTNLGDIHYEPDVQE--MYENLIDPAFAAEIRKLILDDRTFEDMSYYGANFANEE--DH 373
Query: 370 DTVYFTVSDPYGNVTSFINSLYDGFGSCIVPRTFGGFALQNRGANFNLTPGTKNS----- 424
T + +V P G+ S +++ G+ + R G F L + +F+ TPG N+
Sbjct: 374 GTAHISVLAPNGDAISVTSTINSHLGAKVRSRQTG-FILNDEMDDFS-TPGKINAYGIPA 431
Query: 425 -----LEPSKRPYHTIIPSIITSNDESTVYGMGNMGGFMQPSGHVQHFLNLILFGLNPQE 479
++P KRP + PSI+ + +G GG + Q L + ++
Sbjct: 432 SPANFIKPGKRPMSSTCPSIVLDTHGNVKLIVGGAGGSKITTSVAQTILRYFVLHEPIEK 491
Query: 480 SLDSPRCCLSPHPKYSHLDRGRGSSGPVNTPVSLIQLEEDIPEDVFDGLVKLGHEVEYV 538
+++S R P + I +E ++P L +GH++ ++
Sbjct: 492 AVNSGRLHHQLAPMH-------------------IDMEPNVPRHTVAYLSAIGHDIRFL 531
>Hs16506295 [E] KOG2410 Gamma-glutamyltransferase
Length = 666
Score = 94.7 bits (234), Expect = 3e-19
Identities = 122/541 (22%), Positives = 224/541 (40%), Gaps = 55/541 (10%)
Query: 15 QGVVASTQPLASAAGIRILELGGNXXXXXXXXXXXXXXXEPASTGVGGDCFMLHYDESKK 74
QG V + ++ GI +L G+ P S+G+GG ML +D +
Sbjct: 139 QGAVVTDAARCTSLGIEVLSKQGSSVDAAVAAALCLGIVAPHSSGLGGGGVMLVHDIRRN 198
Query: 75 KVVGLNGTGRSPKALDIDHIRSLGIEDVRIPLTSIHSVTVPGTIAGWIDAIEKYGSGRVG 134
+ ++ +P AL + ++ + ++ V VPG + G +A + YG R+
Sbjct: 199 ESHLIDFRESAPGALREETLQRSW--ETKVGTLPGLLVGVPGMVKGLHEAHQLYG--RLP 254
Query: 135 LDAILAPAIKLCKEGHIISEISAYLTGKCWEDLERLNGNDLLKYWAPIDAPLEPPNTGSL 194
+LA A + ++G ++ A E+L N ++ PP GSL
Sbjct: 255 WSQVLAFAAAVAQDGFNVTHDLARALA------EQLPPNMSERFRETFLPSGRPPLPGSL 308
Query: 195 VQNRKLAELLQLVADNGKDGFYK-GVVAESIIEEMKTRGGLMDMDDLAAHKSDFVDPIYL 253
+ LAE+L ++ +G FY G + ++ E + GG++ +D + + + P+
Sbjct: 309 LHRPDLAEVLDVLGTSGPAAFYAGGNLTLEMVAEAQHAGGVITEEDFSNYSALVEKPVCG 368
Query: 254 DFLEHKIWEIPPNSQGLVVLLALGIIRELDNQKLINLHSMQRNSVEYLHMLIECLKLAFY 313
+ H + PP G ++ AL I+ + L++ + LH + E LK+A
Sbjct: 369 VYRGHLVLSPPPPHTGPALISALNILEGFNLTSLVSRE-------QALHWVAETLKIALA 421
Query: 314 DSDEYVSDPNCQEADILHRLLSKDYLKSRAKLFSPSGIIDSSVIKHG--VPNEDFNQSDT 371
+ + DP ++ I S D + S+ + G I+ S +P + + + T
Sbjct: 422 LASR-LGDP-VYDSTITE---SMDDMLSKVEAAYLRGHINDSQAAPAPLLPVYELDGAPT 476
Query: 372 -VYFTVSDPYGNVTSFINSLYDGFGSCIVPRT-------FGGFALQNRGANFNLTPGTKN 423
+ P + + ++SL FGS ++ + F+ NR AN + P +N
Sbjct: 477 AAQVLIMGPDDFIVAMVSSLNQPFGSGLITPSGILLNSQMLDFSWPNRTANHS-APSLEN 535
Query: 424 SLEPSKRPYHTIIPSIITSNDE--STVYGMGNMGGFMQPSGHVQHFLNLILFGLNPQESL 481
S++P KRP ++P+++ + T +G G SG Q LN++ N +SL
Sbjct: 536 SVQPGKRPLSFLLPTVVRPAEGLCGTYLALGANGAARGLSGLTQVLLNVLTLNRNLSDSL 595
Query: 482 DSPRCCLSPHPKYSHLDRGRGSSGPVNTPVSLIQLEEDIPEDVFDGLVKLGHEVEYVRGL 541
R HP + +L+Q++ + E+ + L GH VE V L
Sbjct: 596 ARGRL----HP---------------DLQSNLLQVDSEFTEEEIEFLEARGHHVEKVDVL 636
Query: 542 S 542
S
Sbjct: 637 S 637
>CE23612 [E] KOG2410 Gamma-glutamyltransferase
Length = 642
Score = 94.0 bits (232), Expect = 6e-19
Identities = 118/505 (23%), Positives = 200/505 (39%), Gaps = 45/505 (8%)
Query: 14 TQGVVASTQPLASAAGIRILELGGNXXXXXXXXXXXXXXXEPASTGVGGDCFMLHYDESK 73
++ VA+ + S G IL GGN + S G+GG FM Y+ +
Sbjct: 102 SKAAVAADNEICSEIGRNILLKGGNAVDSAIAALFCIGVMDTHSAGIGGGHFMTIYNATT 161
Query: 74 KKVVGLNGTGRSPKALDIDHIRSLGIEDVRIPLTSIHSVTVPGTIAGWIDAIEKYGSGRV 133
K+ ++ +P A + R + RI +I VPG + G E++GSG+V
Sbjct: 162 KECTVIDAREIAPLAATEEMYRDKWNQS-RIGWKAI---AVPGELHGLRTEFERFGSGKV 217
Query: 134 GLDAILAPAIKLCKEGHIISEISAYLTGKCWEDLERLNGNDLLKYWAPIDAPLEPPNTGS 193
+L P I L EG+ S A + LN N+ P P T
Sbjct: 218 EWRQLLKPTIDLLAEGYPTSHALA----------KALNQNEHQIRAEPTMKNFINPETQR 267
Query: 194 LVQ-------NRKLAELLQLVADNGKD--GFYKGVVAESIIEEMKTRGGLMDMDDLAAHK 244
+ Q + L E +L+A++ FY G +AE + +E + GG++ + D +K
Sbjct: 268 VFQPGEQIKTRQNLLETFRLLANSTDPIADFYTGRLAEQLAKEFEANGGIIRLQDFKNYK 327
Query: 245 S---DFVDPIYLDFLEHKIWEIPPNSQGLVVLLALGIIRELDNQKLINLHSMQRNSVEYL 301
S D + IY + PP G V A I+ +D + N+ S + Y
Sbjct: 328 SIVHDSKNVIYTKLKNGRGVCGPPPPSGSAV--AQAILNVMDGFEY-NMKSFNEIATLYH 384
Query: 302 HMLIECLKLAFYDSDEYVSDPN--CQEADILHRLLSKDYLK-SRAKLFSPSGIIDSSVIK 358
H L E K + Y + ++ DP +I + SK++ R+K+ + D
Sbjct: 385 HFL-ESSKFS-YAARSWLGDPQFVANATEIAKNITSKEWADWVRSKITDTTHPDDYYGGS 442
Query: 359 HGVPNEDFNQSDTVYFTVSDPYGNVTSFINSLYDGFGSCIVPRTFG--------GFALQN 410
P +D T + ++ D GN S +++ G+ + + G F+
Sbjct: 443 FEAPPQDHG---TTHVSIIDADGNAVSVTSTINLYLGALVSSESTGILWNNEMDDFSTPG 499
Query: 411 RGANFNLTPGTKNSLEPSKRPYHTIIPSIITSNDESTVYGMGNMGGFMQPSGHVQHFLNL 470
F P N + P KRP + P +I + + + +G GG SG L+
Sbjct: 500 HPNFFGFPPSPANFIRPGKRPMSSQSPLVIFNTKGAELMAVGGAGGSTIISGVAGVALHA 559
Query: 471 ILFGLNPQESLDSPRCCLSPHPKYS 495
+ + ++++D+PR P Y+
Sbjct: 560 LWLKADVKQAVDAPRMHNQLQPNYT 584
>7293479 [E] KOG2410 Gamma-glutamyltransferase
Length = 561
Score = 89.4 bits (220), Expect = 1e-17
Identities = 112/481 (23%), Positives = 184/481 (37%), Gaps = 61/481 (12%)
Query: 3 FNASRRSVVYSTQGVVASTQPLASAAGIRILELGGNXXXXXXXXXXXXXXXEPASTGVGG 62
F R +Y + G V S +A G +L GG+ P S G+GG
Sbjct: 11 FGLKNRDTLYIS-GAVVSNGIGCAAVGGEMLTDGGSAVDAAIATLLCEGLLLPHSMGIGG 69
Query: 63 DCFMLHYDESKKKVVGLNGTGRSPKALDIDHIRSLGIEDVRIPLTSIHSVTVPGTIAGWI 122
Y S +KV + +P A D +T S VPG I G+
Sbjct: 70 GFVATIYTRSSRKVETVIARESAPAAAHKDMFVG------ETSITGAKSGAVPGEILGYW 123
Query: 123 DAIEKYGSGRVGLDAILAPAIKLCKEGHIISEISAYLTGKCWEDLERLNGNDLLKYWAPI 182
+ +YG + + P+IKL +EGH++S YL L+ + + L +
Sbjct: 124 EMHRRYGI--LPWKRLFEPSIKLAREGHVVSR---YLAAAIQSKLDNIKADPGLSA-VFL 177
Query: 183 DAPLEPPNTGSLVQNRKLAELLQLVADNGKDGFYK-GVVAESIIEEMKTRGGLMDMDDLA 241
+A +P G ++ LA+ L+ +A+NG FY G +E+++ GG++ DL
Sbjct: 178 NATGDPHLEGDYMKRPALADTLERIAENGAKEFYDGGETGRKFVEDIQKMGGIITEQDLR 237
Query: 242 ---------AHKSDFVDPIYLDFLEHKIWEIPPNSQGLVVLLALGIIREL--DNQKLINL 290
H S V Y ++ P S G V+ L ++ +L DN+ +
Sbjct: 238 DYTVRWESDGHVSAHVSGTY------TLYSTPMPSSGPVLAFILNLMADLYTDNEPI--- 288
Query: 291 HSMQRNSVEYLHMLIECLKLAFYD----SDEYVSDPNCQEAD-ILHRLLSKDYLKSRAKL 345
Y ++E K A+ D Y + + L +L ++L+S KL
Sbjct: 289 ---------YWQRVVEAFKHAYGQRTNLGDMYADPVSAASINATLEEMLKPEFLESVRKL 339
Query: 346 FSPSGIIDSSVIKHGVPNEDFNQSDTVYFTVSDPYGNVTSFINSLYDGFGSCIVPRTFGG 405
+ + +G T + V G+ S +++ + FGS V T G
Sbjct: 340 IHDNS-TSEDYLYYGANFTVEEDHGTAHMNVLATNGDAVSITSTINNYFGS-KVASTQTG 397
Query: 406 FALQNRGANFNLTPGT----------KNSLEPSKRPYHTIIPSIITSNDESTVYGMGNMG 455
L + +F+ TPG N + P KRP ++ P II + + +G G
Sbjct: 398 IILNDEMDDFS-TPGVINGFGVPASPANYIYPGKRPMSSMSPCIIVDQEGNVRLLVGAAG 456
Query: 456 G 456
G
Sbjct: 457 G 457
>Hs4758432 [E] KOG2410 Gamma-glutamyltransferase
Length = 586
Score = 85.5 bits (210), Expect = 2e-16
Identities = 117/531 (22%), Positives = 216/531 (40%), Gaps = 63/531 (11%)
Query: 18 VASTQPLASAAGIRILELGGNXXXXXXXXXXXXXXXEPASTGVGGDCFMLHYDESKKKVV 77
VA+ + S G IL+ G+ P S G+GG Y+ + KV
Sbjct: 46 VAADSKVCSDIGRAILQQQGSPVDATIAALVCTSVVNPQSMGLGGGVIFTIYNVTTGKVE 105
Query: 78 GLNGTGRSPKALDIDHIRSLGIEDVR-IPL-TSIHSVTVPGTIAGWIDAIEKYGSGRVGL 135
+N P + H SL + + +PL T + VPG + G+ +A ++G R+
Sbjct: 106 VINARETVPAS----HAPSLLDQCAQALPLGTGAQWIGVPGELRGYAEAHRRHG--RLPW 159
Query: 136 DAILAPAIKLCKEGHIISEI-SAYLTGKCWEDLERLNGNDLLKYWAPIDAPLEPPNTGSL 194
+ P I L + GH+++ + S +L L + L + + PL P +
Sbjct: 160 AQLFQPTIALLRGGHVVAPVLSRFLHNSILRP--SLQASTLRQLFFNGTEPLRPQDP--- 214
Query: 195 VQNRKLAELLQLVADNGKDGFYKGVVAESIIEEMKTRGGLMDMDDLAAHKSDFVDPIYLD 254
+ LA L+ VA G + FY G + + ++E++ G + + DLA + + VD + +
Sbjct: 215 LPWPALATTLETVATEGVEVFYTGRLGQMLVEDIAKEGSQLTLQDLAKFQPEVVDALEVP 274
Query: 255 FLEHKIWEIPPNSQGLVVLLALGIIRELDNQKLINLHSMQR--NSVEYLHMLIECLKLA- 311
++ ++ PP + G ++ L ++R + + SM R V H L+E LK A
Sbjct: 275 LGDYTLYSPPPPAGGAILSFILNVLRGFN----FSTESMARPEGRVNVYHHLVETLKFAR 330
Query: 312 --FYDSDEYVSDPNCQEADILHRLLSKDYL-KSRAKLFSP--SGIIDSSVIKHGVPNEDF 366
+ + S P Q A S+D L ++ A+L G D + + +
Sbjct: 331 GQRWRLGDPRSHPKLQNA-------SRDLLGETLAQLIRQQIDGRGDHQLSHYSLAEAWG 383
Query: 367 NQSDTVYFTVSDPYGNVTSFINSLYDGFGSCIV-PRTFGGFALQNR-------------- 411
+ + T + +V G+ + +++ FG+ + PRT G L N
Sbjct: 384 HGTGTSHVSVLGEDGSAVAATSTINTPFGAMVYSPRT--GIILNNELLDLCERCPWGSGT 441
Query: 412 ------GANFNLTPGTKNSLEPSKRPYHTIIPSIITSNDESTVYGMGNMGGFMQPSGHVQ 465
G PG P +R +++PSI+ + + + +G GG + S Q
Sbjct: 442 TPSPVSGDRVGGAPGRCWPPVPGERSPSSMVPSILINKAQGSKLVIGGAGGELIISAVAQ 501
Query: 466 HFLNLILFGLNPQESLDSP------RCCLSPHPKYS-HLDRGRGSSGPVNT 509
++ + G + + ++ +P + C+ P +S + RG G T
Sbjct: 502 AIMSKLWLGFDLRAAIAAPILHVNSKGCVEYEPNFSQEVQRGLQDRGQNQT 552
>7292730 [E] KOG2410 Gamma-glutamyltransferase
Length = 612
Score = 81.3 bits (199), Expect = 4e-15
Identities = 102/457 (22%), Positives = 179/457 (38%), Gaps = 48/457 (10%)
Query: 14 TQGVVASTQPLASAAGIRILELGGNXXXXXXXXXXXXXXXEPASTGVGGDCFMLHYDESK 73
++ + S + S ++LE GG+ S G+GG M Y +
Sbjct: 78 SRAAICSDSDVCSQLAKKVLENGGSAVDGALAALICNGLIGMQSMGIGGGMVMNVYVAKE 137
Query: 74 KKVVGLNGTGRSPKALDIDHIRSLGIEDVRIPLTSIHSVTVPGTIAGWIDAIEKYGSGRV 133
K + +P AL D+ S D + S S+ VP +AG+ A +++G R+
Sbjct: 138 NKSYSILAREMAPLALRADNFSSF--RDEQDFKRSGWSIAVPAELAGYAVAHQRFG--RL 193
Query: 134 GLDAILAPAIKLCKEGHIISEISAYLTGKCWEDLERLNGNDLLKYWAPIDAPLEPPNTGS 193
++ P ++LC+ G Y K D LN D+++ + + P+TG
Sbjct: 194 KWKDLVLPTLELCRRG--------YRLYKHQYDALILN-QDMIRADSGLRRMFIDPDTGR 244
Query: 194 -------LVQNRKLAELLQLVADNGKDGFYKGVVAESIIEEMKTRGGLMDMDDLAAHKSD 246
+ +L +A+ G FY+G +A+ ++ ++K G + +DL +
Sbjct: 245 FWPLGHLIRPAAQLCNTYDRLANEGPLSFYRGSIADDLLADLKDAGSAITKEDLNQAHAK 304
Query: 247 FVDPIYLDFLEHKIWEIPPNSQGLVVLLALGIIRELDNQKLINLHSMQRNSVEYLHMLIE 306
I + E+ + PP G V+ + I++E + S +H+++E
Sbjct: 305 LSSAIVMPLDEYDLHLTPPPGSGHVLGFIMNILKEFRAE----FSRAGTMSPRQIHLMVE 360
Query: 307 CLKLAF---YDSDEYVSDPNCQEADILHRLLSKDYLKSRAKLFSPSGIIDSSVIKHGVPN 363
+K F + DE S+ ++L L S + KS A+ + + + P
Sbjct: 361 AMKFGFVKRWQLDESASE------ELLSNLTSHELAKSVARQINHTHTFNRPEFYGASPG 414
Query: 364 EDFNQSDTVYFTVSDPYGN----VTSFINSLYDGFG------SCIVPRTFGGFALQNRGA 413
T S +GN VTS IN Y G G I F+++
Sbjct: 415 IQIRDEHGTAHT-SVLHGNDAVSVTSSIN-FYFGSGRTGRRTGVIFNNAMSDFSIEQLKN 472
Query: 414 NFNL--TPGTKNSLEPSKRPYHTIIPSIITSNDESTV 448
F+L PGT N + P+ RP ++ P I+T V
Sbjct: 473 YFDLPFVPGT-NGVAPAARPMSSMCPVIVTERATGNV 508
>Hs4885271 [E] KOG2410 Gamma-glutamyltransferase
Length = 569
Score = 76.3 bits (186), Expect = 1e-13
Identities = 97/485 (20%), Positives = 202/485 (41%), Gaps = 33/485 (6%)
Query: 14 TQGVVASTQPLASAAGIRILELGGNXXXXXXXXXXXXXXXEPASTGVGGDCFMLHYDESK 73
T+ VA+ S G L GG+ S G+GG F+ Y+ +
Sbjct: 39 TRAAVAADAKQCSKIGRDALRDGGSAVDAAIAALLCVGLMNAHSMGIGGGLFLTIYNSTT 98
Query: 74 KKVVGLNGTGRSPKALDIDHIRSLGIEDVRIPLTSIHSVTVPGTIAGWIDAIEKYGSGRV 133
+K +N +P+ S + + L SV VPG I G+ A +++G R+
Sbjct: 99 RKAEVINAREVAPRLAFATMFNS-SEQSQKGGL----SVAVPGEIRGYELAHQRHG--RL 151
Query: 134 GLDAILAPAIKLCKEGHIISE-ISAYLTGKCWEDLERLNGNDLLKYWAPIDAPLEPPNTG 192
+ P+I+L ++G + + ++A L K ++ L + + L
Sbjct: 152 PWARLFQPSIQLARQGFPVGKGLAAALENKRTVIEQQ---PVLCEVFCRDRKVLREGERL 208
Query: 193 SLVQNRKLAELLQLVADNGKDGFYKGVVAESIIEEMKTRGGLMDMDDLAAHKSDFVD-PI 251
+L Q LA+ + +A G FY G + I+++++ GG++ +DL ++++ ++ P+
Sbjct: 209 TLPQ---LADTYETLAIEGAQAFYNGSLTAQIVKDIQAAGGIVTAEDLNNYRAELIEHPL 265
Query: 252 YLDFLEHKIWEIPPNSQGLVVLLALGIIRELDNQKLINLHSMQRNSVEYLHMLIECLKLA 311
+ + ++ G V+ L L I++ N ++ S ++ + Y H ++E + A
Sbjct: 266 NISLGDAVLYMPSAPLSGPVLALILNILKGY-NFSRESVESPEQKGLTY-HRIVEAFRFA 323
Query: 312 FYDSDEYVSDPNCQEADILHRLLSKDYLKSRAKLFSPSGIIDSSVIKHGVPNEDFNQSD- 370
Y + DP + + R ++ ++ ++ + + I D + +F D
Sbjct: 324 -YAKRTLLGDPKFVDVTEVVRNMTSEFFAAQLR----AQISDDTTHPISYYKPEFYTPDD 378
Query: 371 --TVYFTVSDPYGNVTSFINSLYDGFGSCIVPRTFG--------GFALQNRGANFNLTPG 420
T + +V G+ S +++ FGS + G F+ + F + P
Sbjct: 379 GGTAHLSVVAEDGSAVSATSTINLYFGSKVRSPVSGILFNNEMDDFSSPSITNEFGVPPS 438
Query: 421 TKNSLEPSKRPYHTIIPSIITSNDESTVYGMGNMGGFMQPSGHVQHFLNLILFGLNPQES 480
N ++P K+P ++ P+I+ D +G GG + + + FG + + +
Sbjct: 439 PANFIQPGKQPLSSMCPTIMVGQDGQVRMVVGAAGGTQITTATALAIIYNLWFGYDVKRA 498
Query: 481 LDSPR 485
++ PR
Sbjct: 499 VEEPR 503
>CE26318 [E] KOG2410 Gamma-glutamyltransferase
Length = 841
Score = 66.6 bits (161), Expect = 1e-10
Identities = 53/220 (24%), Positives = 103/220 (46%), Gaps = 13/220 (5%)
Query: 26 SAAGIRILELGGNXXXXXXXXXXXXXXXEPASTGVGGDCFMLHYDESKKKVVGLNGTGRS 85
S G +I E GGN P +TG G ++ + + K ++G R+
Sbjct: 333 SEIGKKIHETGGNAVDAMVATEFCISAVHPHTTGPGFGAVIVLHSKKKNGTFVIDGRERA 392
Query: 86 PKALDIDHIRSLGIEDVRIPLTSIHSVTVPGTIAGWIDAIEKYGSGRVGLDAILAPAIKL 145
PK + ++ + + I S+ VPG I+ A +++GSG++ +++ P I+L
Sbjct: 393 PKNAN----KNTFVINPTIAHIGYSSMGVPGWISVLWTAYKQFGSGKIVWKSLIEPTIEL 448
Query: 146 CKEGHIISEISAYLTGKCWEDLERLNGNDLLKYWAPIDAPLEPPNTGSLVQNRKLAELLQ 205
K + + L G+ +E N +L + + + G++++N + + L+
Sbjct: 449 LKTNRVRID---RLLGQAFESRR----NHILHEKSFDNWLSQATREGAVLRNEQYEDFLK 501
Query: 206 LVADN--GKDGFYKGVVAESIIEEMKTRGGLMDMDDLAAH 243
L+ ++ + FY G + I+EEMK+RGGL+ DL ++
Sbjct: 502 LLKESVHAEHDFYGGQFVKIIVEEMKSRGGLISRQDLESY 541
>CE13762_2 [E] KOG2410 Gamma-glutamyltransferase
Length = 399
Score = 63.5 bits (153), Expect = 8e-10
Identities = 96/434 (22%), Positives = 162/434 (37%), Gaps = 61/434 (14%)
Query: 15 QGVVASTQPLASAAGIRILELGGNXXXXXXXXXXXXXXXEPASTGVGGDCFMLHYDESKK 74
+ V ++ SA G IL GGN P +GG M+
Sbjct: 1 RAAVFTSSAECSAIGKSILVRGGNAVEAAIAASFCLMGAMPNKASLGGG-LMMTVKTKNG 59
Query: 75 KVVGLNGTGRSPKALDIDHIRSLGIEDVRIPLTSIHSVTVPGTIAGWIDAIEKYGSGRVG 134
+ +P DID ++ ++ + + PGT+ G A +K+ S RV
Sbjct: 60 NATTIIARETAPMNADIDELK----KNPELTHVGPKASGTPGTLNGLYRAFQKFSSNRVQ 115
Query: 135 LDAILAPAIKLCKEGHIISEISAYLTGKCWEDLERLNGNDLLKYWAPIDAPLEPPNTGSL 194
++ P I+ C +G +S EDL++ + L + + +
Sbjct: 116 WKHLVLPTIQQCNKGFKLS-----------EDLKKRSSAPALAQFFKANVQKDK------ 158
Query: 195 VQNRKLAELLQLVAD--NGKDGFYKGVVAESIIEEMKTRGGLMDMDDLAAHKSDFVDPIY 252
+ L+ LL +AD + D FY G A+ + +E+ GG M DL ++SD I
Sbjct: 159 ILCTSLSTLLTDIADYESPLDAFYHGETAQKLAKEL---GGYMTASDLEDYESDMSSAIC 215
Query: 253 LDF-LEHKIWEIPPNSQGLVVLLALGIIRELDNQKLINLHSMQRNSVEYLHMLIECLKLA 311
+ ++ K+ P S +LA + + L ++ + R+S+ + +
Sbjct: 216 SEIDVDTKV--CGPGSPSSFAVLANTYLATKNMSNLAKVNDVLRSSMGLISKI------- 266
Query: 312 FYDSDEYVSDPNCQEADILHRLLSKDYLKSRAKLFSPSGIIDSSVIKHGVPNEDFNQSDT 371
AD + SK Y + AK S SS K+ N F + +
Sbjct: 267 ---------------ADPMFVKSSKKYTEELAKTSKRS----SSEAKNLAVN--FKEDGS 305
Query: 372 VYFTVSDPYGNVTSFINSLYDGFGSCIVPRTFGGFALQNRGANFNL-TPGTKNSLEPSKR 430
V D S + SL D FGS I + GF N+ F++ SL+P K
Sbjct: 306 TEVFVIDENNMTVSVLLSLGDDFGSLIY--SSSGFFWNNKLRYFDVKNENVPLSLQPGKV 363
Query: 431 PYHTIIPSIITSND 444
P + P ++ N+
Sbjct: 364 PTSLLSPIVVVKNN 377
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.317 0.138 0.410
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 37,483,543
Number of Sequences: 60738
Number of extensions: 1760111
Number of successful extensions: 3698
Number of sequences better than 1.0e-05: 19
Number of HSP's better than 0.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 3629
Number of HSP's gapped (non-prelim): 26
length of query: 581
length of database: 30,389,216
effective HSP length: 112
effective length of query: 469
effective length of database: 23,586,560
effective search space: 11062096640
effective search space used: 11062096640
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)