ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI6185 check: MH T KOG0032 Signal transduction mechanisms Ca2+/calmodulin-dependent protein kinase, EF-Hand protein superfamily
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI6185 2157146 2158426 427
(427 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YOL016c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 509 e-144
YFR014c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 461 e-129
SPACUNK12.02c [T] KOG0032 Ca2+/calmodulin-dependent protein kina... 231 2e-60
Hs14196445 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 216 4e-56
7304311 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 211 2e-54
CE25046 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 211 2e-54
Hs9966875 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 209 8e-54
Hs4502553 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 205 9e-53
Hs4502557 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 202 1e-51
CE28058 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 190 4e-48
CE28055 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 190 4e-48
CE28053 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 190 4e-48
Hs14141724 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase ... 188 1e-47
7304358 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 187 3e-47
CE28056 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 186 4e-47
CE28059 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 185 1e-46
CE28057 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 185 1e-46
CE28054 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 185 1e-46
CE28051 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 185 1e-46
CE28060 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 185 1e-46
CE28061 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 184 2e-46
Hs7706286 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase E... 181 1e-45
Hs4826684_1 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 180 4e-45
Hs14728804 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 179 7e-45
Hs20127418 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase ... 178 2e-44
Hs4557511 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 176 5e-44
Hs14776113 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 176 8e-44
At2g31500 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 175 1e-43
At5g19360 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 174 2e-43
At5g12180 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 173 4e-43
Hs13129008 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 172 7e-43
At4g04720 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 172 7e-43
At2g41860 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 172 9e-43
Hs20149547 [T] KOG0603 Ribosomal protein S6 kinase 172 1e-42
At4g04740 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 172 1e-42
At5g19450 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 171 3e-42
Hs4758128_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 171 3e-42
At3g51850 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 168 1e-41
At1g76040 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 167 3e-41
At2g17890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 166 5e-41
At1g61950 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 166 6e-41
Hs14670383 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 166 8e-41
At4g21940 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 166 8e-41
Hs4759050 [T] KOG0603 Ribosomal protein S6 kinase 164 2e-40
Hs22043888 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 163 4e-40
At3g57530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 163 5e-40
At3g20410 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 161 2e-39
At1g12580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 161 2e-39
CE12518 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 160 3e-39
7295638 [T] KOG0603 Ribosomal protein S6 kinase 160 3e-39
Hs7657526 [T] KOG0603 Ribosomal protein S6 kinase 160 4e-39
Hs20479818 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 160 4e-39
At1g18890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 159 6e-39
At3g19100 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 159 1e-38
Hs6005850 [D] KOG0615 Serine/threonine protein kinase Chk2 and r... 158 1e-38
Hs4758700 [T] KOG0604 MAP kinase-activated protein kinase 2 158 1e-38
Hs14916455 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 158 1e-38
At5g66210 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 158 2e-38
At4g36070 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 158 2e-38
At4g09570 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 158 2e-38
At1g35670 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 158 2e-38
At4g23650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 157 3e-38
At3g56760 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 157 3e-38
At1g50700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 157 3e-38
YDL101c [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 157 4e-38
At5g23580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 157 4e-38
At3g50530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 157 4e-38
At5g39440 [T] KOG0583 Serine/threonine protein kinase 156 5e-38
At1g49580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 154 2e-37
At1g30270 [T] KOG0583 Serine/threonine protein kinase 154 2e-37
At3g10660 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 154 3e-37
YGL158w [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 152 1e-36
At2g41140 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 152 1e-36
Hs19923570 [T] KOG0603 Ribosomal protein S6 kinase 150 3e-36
Hs14589904 [T] KOG0604 MAP kinase-activated protein kinase 2 150 3e-36
At5g04870 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 150 3e-36
At2g26980 [T] KOG0583 Serine/threonine protein kinase 150 3e-36
At1g01140 [T] KOG0583 Serine/threonine protein kinase 150 3e-36
Hs22062450 [R] KOG0586 Serine/threonine protein kinase 149 6e-36
CE27768 [R] KOG0586 Serine/threonine protein kinase 149 6e-36
CE23838 [R] KOG0586 Serine/threonine protein kinase 149 6e-36
At5g35410 [T] KOG0583 Serine/threonine protein kinase 149 6e-36
SPCC18B5.11c [D] KOG0615 Serine/threonine protein kinase Chk2 an... 149 1e-35
At1g74740 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 148 1e-35
SPCC1322.08 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 148 2e-35
Hs14777335 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 148 2e-35
Hs10863901 [T] KOG0604 MAP kinase-activated protein kinase 2 148 2e-35
At2g35890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 147 3e-35
SPAC14C4.03 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 147 4e-35
At3g29160 [T] KOG0583 Serine/threonine protein kinase 147 4e-35
At2g30360 [T] KOG0583 Serine/threonine protein kinase 147 4e-35
Hs4759052 [T] KOG0603 Ribosomal protein S6 kinase 146 5e-35
At5g24430 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 146 5e-35
At3g17510 [T] KOG0583 Serine/threonine protein kinase 146 5e-35
Hs9845489 [R] KOG0586 Serine/threonine protein kinase 146 7e-35
Hs9845487 [R] KOG0586 Serine/threonine protein kinase 146 7e-35
Hs8923922 [R] KOG0586 Serine/threonine protein kinase 146 7e-35
At4g35310 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 146 7e-35
7298652 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 145 9e-35
7290629 [T] KOG0604 MAP kinase-activated protein kinase 2 145 9e-35
At3g01090 [T] KOG0583 Serine/threonine protein kinase 145 1e-34
CE18058_1 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 145 1e-34
CE09360 [Z] KOG0613 Projectin/twitchin and related proteins 145 1e-34
At1g12680 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 145 1e-34
At4g38230 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 144 3e-34
CE27583 [T] KOG0604 MAP kinase-activated protein kinase 2 144 3e-34
CE17545 [T] KOG0604 MAP kinase-activated protein kinase 2 144 3e-34
At2g17290 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 143 4e-34
At2g46700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 143 6e-34
HsM4505103 [R] KOG0586 Serine/threonine protein kinase 142 1e-33
At5g45820 [T] KOG0583 Serine/threonine protein kinase 142 1e-33
Hs13899225 [R] KOG0586 Serine/threonine protein kinase 141 2e-33
At2g38910 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 141 2e-33
CE05507 [T] KOG0603 Ribosomal protein S6 kinase 141 2e-33
YMR001c [D] KOG0575 Polo-like serine/threonine protein kinase 140 3e-33
Hs16950621 [Z] KOG0613 Projectin/twitchin and related proteins 140 3e-33
Hs16950613 [Z] KOG0613 Projectin/twitchin and related proteins 140 3e-33
Hs16950611 [Z] KOG0613 Projectin/twitchin and related proteins 140 3e-33
Hs16950601 [Z] KOG0613 Projectin/twitchin and related proteins 140 3e-33
At3g49370 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 140 3e-33
7304283 [Z] KOG0613 Projectin/twitchin and related proteins 140 3e-33
Hs4758192 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 140 4e-33
At4g24400 [T] KOG0583 Serine/threonine protein kinase 140 4e-33
7299438 [R] KOG0586 Serine/threonine protein kinase 140 5e-33
7299437 [R] KOG0586 Serine/threonine protein kinase 139 6e-33
At1g48260 [T] KOG0583 Serine/threonine protein kinase 139 8e-33
YKL101w [D] KOG0588 Serine/threonine protein kinase 139 1e-32
YDR507c [D] KOG0588 Serine/threonine protein kinase 139 1e-32
Hs22057171 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 139 1e-32
At5g25110 [T] KOG0583 Serine/threonine protein kinase 139 1e-32
At2g38490 [T] KOG0583 Serine/threonine protein kinase 139 1e-32
YPL153c [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 138 1e-32
SPAC23A1.06c [T] KOG0032 Ca2+/calmodulin-dependent protein kinas... 138 1e-32
Hs5453882 [G] KOG0599 Phosphorylase kinase gamma subunit 138 2e-32
CE28218 [D] KOG0588 Serine/threonine protein kinase 138 2e-32
At4g04710 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 138 2e-32
Hs7662170 [R] KOG0611 Predicted serine/threonine protein kinase 137 2e-32
CE18169 [T] KOG0603 Ribosomal protein S6 kinase 137 2e-32
CE13014 [T] KOG0603 Ribosomal protein S6 kinase 137 2e-32
CE00847 [T] KOG0583 Serine/threonine protein kinase 137 2e-32
At5g01820 [T] KOG0583 Serine/threonine protein kinase 137 2e-32
At4g04700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 137 2e-32
Hs4502567_1 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase... 137 2e-32
Hs4505785 [G] KOG0599 Phosphorylase kinase gamma subunit 137 3e-32
At5g10930 [T] KOG0583 Serine/threonine protein kinase 136 5e-32
At4g30960 [T] KOG0583 Serine/threonine protein kinase 136 5e-32
YLR248w [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 136 7e-32
7290249 [R] KOG0586 Serine/threonine protein kinase 136 7e-32
Hs6005922_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 136 7e-32
7302464 [R] KOG0586 Serine/threonine protein kinase 135 9e-32
7294217 [D] KOG0588 Serine/threonine protein kinase 135 9e-32
7292679 [G] KOG0599 Phosphorylase kinase gamma subunit 135 9e-32
CE05780 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 135 1e-31
7303211 [T] KOG4717 Serine/threonine protein kinase 135 1e-31
Hs5453966 [T] KOG0583 Serine/threonine protein kinase 134 2e-31
7303019 [Z] KOG0613 Projectin/twitchin and related proteins 134 2e-31
7293666 [D] KOG0575 Polo-like serine/threonine protein kinase 134 2e-31
Hs21361643 [T] KOG4717 Serine/threonine protein kinase 134 3e-31
At4g14580 [T] KOG0583 Serine/threonine protein kinase 134 3e-31
7300778 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 134 3e-31
At5g45810 [T] KOG0583 Serine/threonine protein kinase 134 3e-31
Hs4506735 [T] KOG0603 Ribosomal protein S6 kinase 133 6e-31
ECU03g0980 [T] KOG0583 Serine/threonine protein kinase 133 6e-31
Hs4758194 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 132 1e-30
7302570 [R] KOG0586 Serine/threonine protein kinase 132 1e-30
Hs21361133 [R] KOG0586 Serine/threonine protein kinase 132 1e-30
YDR477w [T] KOG0583 Serine/threonine protein kinase 131 2e-30
HsM4506035 [T] KOG0604 MAP kinase-activated protein kinase 2 131 2e-30
Hs5453964 [T] KOG0583 Serine/threonine protein kinase 131 2e-30
YOR351c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 131 2e-30
CE24761 [D] KOG0580 Serine/threonine protein kinase 131 2e-30
At3g23000 [T] KOG0583 Serine/threonine protein kinase 131 2e-30
At2g25090 [T] KOG0583 Serine/threonine protein kinase 131 2e-30
At1g29230 [T] KOG0583 Serine/threonine protein kinase 131 2e-30
CE18967 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD a... 130 3e-30
At5g01810 [T] KOG0583 Serine/threonine protein kinase 130 3e-30
Hs4826948 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 130 4e-30
Hs4758016 [D] KOG0575 Polo-like serine/threonine protein kinase 130 4e-30
YOR233w [T] KOG0583 Serine/threonine protein kinase 130 5e-30
CE06635 [Z] KOG0613 Projectin/twitchin and related proteins 130 5e-30
CE06634 [Z] KOG0613 Projectin/twitchin and related proteins 130 5e-30
At4g18700 [T] KOG0583 Serine/threonine protein kinase 130 5e-30
7296450 [D] KOG0575 Polo-like serine/threonine protein kinase 130 5e-30
Hs21237768 [T] KOG0604 MAP kinase-activated protein kinase 2 129 6e-30
Hs21237765 [T] KOG0604 MAP kinase-activated protein kinase 2 129 6e-30
CE26793_1 [R] KOG0611 Predicted serine/threonine protein kinase 129 6e-30
Hs7661974 [T] KOG0583 Serine/threonine protein kinase 129 8e-30
7290150 [T] KOG0583 Serine/threonine protein kinase 129 1e-29
Hs21359873 [D] KOG0575 Polo-like serine/threonine protein kinase 128 1e-29
Hs14770402 [R] KOG0586 Serine/threonine protein kinase 128 1e-29
Hs13569922 [R] KOG0611 Predicted serine/threonine protein kinase 128 1e-29
At4g40010 [T] KOG0583 Serine/threonine protein kinase 128 1e-29
7299322 [R] KOG0611 Predicted serine/threonine protein kinase 128 1e-29
SPAC23C11.16 [D] KOG0575 Polo-like serine/threonine protein kinase 127 2e-29
Hs14993776 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 127 3e-29
CE28643 [T] KOG0583 Serine/threonine protein kinase 127 3e-29
CE07458 [T] KOG0583 Serine/threonine protein kinase 127 3e-29
Hs20545245 [D] KOG0588 Serine/threonine protein kinase 127 4e-29
Hs15619015 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 127 4e-29
CE27297 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 127 4e-29
At2g37840 [OUT] KOG0595 Serine/threonine-protein kinase involved... 127 4e-29
7299507 [T] KOG0607 MAP kinase-interacting kinase and related se... 126 5e-29
CE16081 [T] KOG0583 Serine/threonine protein kinase 126 7e-29
At3g08730 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 126 7e-29
YPL141c [T] KOG0583 Serine/threonine protein kinase 125 9e-29
HsM4826916 [D] KOG0575 Polo-like serine/threonine protein kinase 125 1e-28
CE17284 [T] KOG0583 Serine/threonine protein kinase 125 1e-28
Hs20545357 [T] KOG0583 Serine/threonine protein kinase 125 2e-28
CE15473 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 125 2e-28
At3g08720 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 125 2e-28
At1g60940 [T] KOG0583 Serine/threonine protein kinase 125 2e-28
SPBC4F6.06 [T] KOG0583 Serine/threonine protein kinase 124 2e-28
Hs10835065 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 124 2e-28
YPL203w [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 124 3e-28
CE22877 [D] KOG0575 Polo-like serine/threonine protein kinase 124 3e-28
CE15475 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 124 3e-28
YCL024w [T] KOG0583 Serine/threonine protein kinase 124 4e-28
CE03584 [T] KOG0607 MAP kinase-interacting kinase and related se... 124 4e-28
7296128 [T] KOG0583 Serine/threonine protein kinase 124 4e-28
7295426 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 124 4e-28
Hs4506055 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 123 5e-28
CE02377 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 123 5e-28
At4g33950 [T] KOG0583 Serine/threonine protein kinase 123 5e-28
SPBC21.06c [T] KOG0198 MEKK and related serine/threonine protein... 123 6e-28
CE07285 [D] KOG0575 Polo-like serine/threonine protein kinase 123 6e-28
At5g08590 [T] KOG0583 Serine/threonine protein kinase 123 6e-28
CE28479 [T] KOG0583 Serine/threonine protein kinase 122 8e-28
At5g57630 [T] KOG0583 Serine/threonine protein kinase 122 8e-28
At3g50500 [T] KOG0583 Serine/threonine protein kinase 122 8e-28
At5g58380 [T] KOG0583 Serine/threonine protein kinase 122 1e-27
At5g04510 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 122 1e-27
At3g61960 [OUT] KOG0595 Serine/threonine-protein kinase involved... 122 1e-27
At1g09000 [T] KOG0198 MEKK and related serine/threonine protein ... 122 1e-27
Hs20143922 [Z] KOG0613 Projectin/twitchin and related proteins 122 1e-27
Hs20143918 [Z] KOG0613 Projectin/twitchin and related proteins 122 1e-27
Hs20143914 [Z] KOG0613 Projectin/twitchin and related proteins 122 1e-27
Hs19923468 [T] KOG4236 Serine/threonine protein kinase PKC mu/PK... 122 1e-27
Hs19747267 [Z] KOG0613 Projectin/twitchin and related proteins 122 1e-27
At2g45490 [D] KOG0580 Serine/threonine protein kinase 122 1e-27
7300559 [T] KOG4279 Serine/threonine protein kinase 122 1e-27
SPCC74.03c [T] KOG0583 Serine/threonine protein kinase 121 2e-27
HsM8923212 [T] KOG4717 Serine/threonine protein kinase 121 2e-27
CE28251 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 121 2e-27
At5g07070 [T] KOG0583 Serine/threonine protein kinase 121 2e-27
At2g34180 [T] KOG0583 Serine/threonine protein kinase 121 2e-27
At2g23030 [T] KOG0583 Serine/threonine protein kinase 121 2e-27
SPAC57A10.02 [D] KOG0588 Serine/threonine protein kinase 121 2e-27
Hs7657214 [T] KOG0583 Serine/threonine protein kinase 120 3e-27
Hs4506739 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 120 3e-27
Hs18596354 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 120 3e-27
At1g78290 [T] KOG0583 Serine/threonine protein kinase 120 3e-27
Hs4506057 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 120 4e-27
Hs21361433 [D] KOG0575 Polo-like serine/threonine protein kinase 120 4e-27
Hs4506737 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 120 5e-27
At5g66880 [T] KOG0583 Serine/threonine protein kinase 120 5e-27
At1g10940 [T] KOG0583 Serine/threonine protein kinase 120 5e-27
At1g08650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 120 5e-27
7297776 [D] KOG0580 Serine/threonine protein kinase 120 5e-27
Hs9994197 [T] KOG0607 MAP kinase-interacting kinase and related ... 119 7e-27
ECU07g0360 [D] KOG0580 Serine/threonine protein kinase 119 7e-27
Hs4506075 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD... 119 9e-27
HsM7657627 [D] KOG0575 Polo-like serine/threonine protein kinase 119 1e-26
CE22045 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 119 1e-26
YHL007c [T] KOG0578 p21-activated serine/threonine protein kinase 118 1e-26
SPAC644.06c [D] KOG0588 Serine/threonine protein kinase 118 1e-26
At5g63650 [T] KOG0583 Serine/threonine protein kinase 118 1e-26
7297542 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 118 1e-26
ECU01g0630 [D] KOG0575 Polo-like serine/threonine protein kinase 118 2e-26
CE20167 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD a... 118 2e-26
YKL166c [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 117 3e-26
At3g10540 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 117 3e-26
At1g54960 [T] KOG0198 MEKK and related serine/threonine protein ... 117 3e-26
SPCC24B10.07 [RT] KOG0598 Ribosomal protein S6 kinase and relate... 117 3e-26
Hs5031689 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD... 117 4e-26
CE21086 [D] KOG0590 Checkpoint kinase and related serine/threoni... 117 4e-26
Hs5902140_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 117 4e-26
Hs4505695 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 116 6e-26
Hs4502023 [T] KOG0690 Serine/threonine protein kinase 116 7e-26
Hs20127541 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 116 7e-26
At4g08500 [T] KOG0198 MEKK and related serine/threonine protein ... 116 7e-26
YDR122w [T] KOG0583 Serine/threonine protein kinase 115 1e-25
CE26649 [D] KOG0575 Polo-like serine/threonine protein kinase 115 1e-25
CE18454 [T] KOG4717 Serine/threonine protein kinase 115 1e-25
At4g08470 [T] KOG0198 MEKK and related serine/threonine protein ... 115 1e-25
At1g50230 [R] KOG0597 Serine-threonine protein kinase FUSED 115 1e-25
Hs5032091 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 115 2e-25
7301971 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 115 2e-25
7299536 [D] KOG0580 Serine/threonine protein kinase 115 2e-25
7292656 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 115 2e-25
YPL209c [D] KOG0580 Serine/threonine protein kinase 114 2e-25
YHR205w [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 114 2e-25
At3g06030 [T] KOG0198 MEKK and related serine/threonine protein ... 114 2e-25
7291710 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 114 3e-25
YMR104c [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 114 4e-25
CE04603 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 114 4e-25
HsM4505191 [T] KOG0607 MAP kinase-interacting kinase and related... 113 5e-25
Hs16418343 [T] KOG0583 Serine/threonine protein kinase 113 5e-25
Hs14150045 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 113 5e-25
SPBC32C12.03c [T] KOG0583 Serine/threonine protein kinase 113 6e-25
Hs16950615 [Z] KOG0613 Projectin/twitchin and related proteins 113 6e-25
YKL126w [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 112 1e-24
Hs5730055 [D] KOG0575 Polo-like serine/threonine protein kinase 112 1e-24
Hs5174547 [T] KOG4279 Serine/threonine protein kinase 112 1e-24
At5g62310 [TR] KOG0606 Microtubule-associated serine/threonine k... 112 1e-24
7302860 [T] KOG0696 Serine/threonine protein kinase 112 1e-24
7294770 [T] KOG0603 Ribosomal protein S6 kinase 112 1e-24
YLR096w [T] KOG0583 Serine/threonine protein kinase 112 1e-24
YJL164c [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 112 1e-24
Hs4502803 [D] KOG0590 Checkpoint kinase and related serine/threo... 112 1e-24
Hs4507275 [D] KOG0580 Serine/threonine protein kinase 111 2e-24
Hs16950619 [Z] KOG0613 Projectin/twitchin and related proteins 111 2e-24
CE21025 [D] KOG0580 Serine/threonine protein kinase 111 2e-24
SPBC106.10 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 111 2e-24
HsM4507279 [D] KOG0580 Serine/threonine protein kinase 110 3e-24
CE28993 [G] KOG0599 Phosphorylase kinase gamma subunit 110 3e-24
CE27131_1 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase E... 110 4e-24
SPAC9G1.09 [T] KOG0201 Serine/threonine protein kinase 110 5e-24
SPAC9G1.02 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 an... 110 5e-24
Hs5453972 [T] KOG0694 Serine/threonine protein kinase 110 5e-24
Hs4885061 [T] KOG0690 Serine/threonine protein kinase 110 5e-24
Hs18552621 [R] KOG0597 Serine-threonine protein kinase FUSED 110 5e-24
7298323 [D] KOG0590 Checkpoint kinase and related serine/threoni... 110 5e-24
SPCC1259.13 [D] KOG0590 Checkpoint kinase and related serine/thr... 109 7e-24
Hs15451902 [T] KOG0576 Mitogen-activated protein kinase kinase k... 109 7e-24
CE14798 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 109 7e-24
Hs22050308_2 [T] KOG0198 MEKK and related serine/threonine prote... 109 7e-24
SPCC4G3.08 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 109 9e-24
SPAC1B9.02c [RT] KOG0598 Ribosomal protein S6 kinase and related... 109 9e-24
Hs4885549 [T] KOG0690 Serine/threonine protein kinase 109 9e-24
Hs4759178 [D] KOG0580 Serine/threonine protein kinase 109 9e-24
CE15612 [T] KOG0690 Serine/threonine protein kinase 109 9e-24
At1g53570 [T] KOG0198 MEKK and related serine/threonine protein ... 109 9e-24
SPCC576.15c [T] KOG0592 3-phosphoinositide-dependent protein kin... 108 1e-23
Hs14589909 [T] KOG0576 Mitogen-activated protein kinase kinase k... 108 1e-23
YAR019c [T] KOG0198 MEKK and related serine/threonine protein ki... 108 2e-23
SPAC1F5.09c [T] KOG0578 p21-activated serine/threonine protein k... 108 2e-23
At1g69220 [T] KOG0576 Mitogen-activated protein kinase kinase ki... 108 2e-23
Hs20070247_2 [RT] KOG0598 Ribosomal protein S6 kinase and relate... 108 2e-23
SPAC22E12.14c [RT] KOG0598 Ribosomal protein S6 kinase and relat... 108 2e-23
Hs5453970 [T] KOG0694 Serine/threonine protein kinase 108 2e-23
CE03467 [T] KOG0604 MAP kinase-activated protein kinase 2 108 2e-23
At1g49180_1 [OUT] KOG0595 Serine/threonine-protein kinase involv... 108 2e-23
SPAC1F3.02c [T] KOG0198 MEKK and related serine/threonine protei... 107 3e-23
CE03979 [T] KOG0614 cGMP-dependent protein kinase 107 3e-23
7300106 [T] KOG0690 Serine/threonine protein kinase 107 3e-23
SPCC320.12c [D] KOG0580 Serine/threonine protein kinase 107 3e-23
CE27166 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 107 3e-23
At2g25880 [D] KOG0580 Serine/threonine protein kinase 107 3e-23
7302511 [T] KOG0576 Mitogen-activated protein kinase kinase kina... 107 3e-23
YBR028c [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 107 4e-23
Hs4506067 [T] KOG0696 Serine/threonine protein kinase 107 4e-23
Hs17933758 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 107 4e-23
Hs14735945 [T] KOG0694 Serine/threonine protein kinase 107 4e-23
7299793 [T] KOG0583 Serine/threonine protein kinase 107 4e-23
Hs16950617 [Z] KOG0613 Projectin/twitchin and related proteins 106 6e-23
At4g08480 [T] KOG0198 MEKK and related serine/threonine protein ... 106 6e-23
CE21879 [D] KOG0590 Checkpoint kinase and related serine/threoni... 106 8e-23
At1g14000 [T] KOG0192 Tyrosine kinase specific for activated (GT... 106 8e-23
CE19898 [T] KOG0614 cGMP-dependent protein kinase 105 1e-22
CE19897 [T] KOG0614 cGMP-dependent protein kinase 105 1e-22
At4g32830 [D] KOG0580 Serine/threonine protein kinase 105 1e-22
At3g07980 [T] KOG0198 MEKK and related serine/threonine protein ... 105 1e-22
At1g48490 [TR] KOG0606 Microtubule-associated serine/threonine k... 105 1e-22
At4g12020_6 [T] KOG0198 MEKK and related serine/threonine protei... 105 1e-22
YAL017w [T] KOG1152 Signal transduction serine/threonine kinase ... 105 2e-22
Hs5453978 [T] KOG0614 cGMP-dependent protein kinase 105 2e-22
Hs15011880 [T] KOG0201 Serine/threonine protein kinase 105 2e-22
CE28744 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 105 2e-22
SPBC4C3.11 [T] KOG0592 3-phosphoinositide-dependent protein kina... 104 2e-22
Hs7662210 [OUT] KOG0595 Serine/threonine-protein kinase involved... 104 2e-22
Hs4507273 [D] KOG0580 Serine/threonine protein kinase 104 2e-22
Hs20070158 [T] KOG0201 Serine/threonine protein kinase 104 2e-22
At3g13530 [T] KOG0198 MEKK and related serine/threonine protein ... 104 2e-22
SPBC1D7.05c [T] KOG0198 MEKK and related serine/threonine protei... 104 3e-22
SPBC1604.14c [T] KOG0578 p21-activated serine/threonine protein ... 104 3e-22
Hs4507831 [OUT] KOG0595 Serine/threonine-protein kinase involved... 104 3e-22
CE29298 [T] KOG0690 Serine/threonine protein kinase 104 3e-22
CE18646 [T] KOG0690 Serine/threonine protein kinase 104 3e-22
YJL095w [T] KOG0198 MEKK and related serine/threonine protein ki... 103 4e-22
Hs16507245 [T] KOG0583 Serine/threonine protein kinase 103 4e-22
CE29092 [T] KOG0694 Serine/threonine protein kinase 103 4e-22
CE02586 [T] KOG0696 Serine/threonine protein kinase 103 4e-22
CE01554 [T] KOG0986 G protein-coupled receptor kinase 103 4e-22
7300435 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and r... 103 4e-22
7300224 [T] KOG0201 Serine/threonine protein kinase 103 4e-22
7289880 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 103 4e-22
Hs20547806 [R] KOG0589 Serine/threonine protein kinase 103 5e-22
Hs19923407 [D] KOG0591 NIMA (never in mitosis)-related G2-specif... 103 5e-22
At1g63700 [T] KOG0198 MEKK and related serine/threonine protein ... 103 5e-22
YOL100w [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 103 6e-22
CE24516 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 103 6e-22
At1g45160 [TR] KOG0606 Microtubule-associated serine/threonine k... 103 6e-22
7301972 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 103 6e-22
YNR047w [R] KOG0610 Putative serine/threonine protein kinase 102 8e-22
Hs7382496 [T] KOG0578 p21-activated serine/threonine protein kinase 102 8e-22
Hs4758702 [T] KOG4279 Serine/threonine protein kinase 102 8e-22
Hs4505599 [T] KOG0578 p21-activated serine/threonine protein kinase 102 8e-22
CE05274 [T] KOG0690 Serine/threonine protein kinase 102 8e-22
7303860 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 102 8e-22
At3g04530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 102 1e-21
Hs4885349 [T] KOG0986 G protein-coupled receptor kinase 102 1e-21
Hs4826878 [T] KOG0582 Ste20-like serine/threonine protein kinase 102 1e-21
Hs14042966 [T] KOG0583 Serine/threonine protein kinase 102 1e-21
CE20636 [D] KOG0590 Checkpoint kinase and related serine/threoni... 102 1e-21
7299160 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 102 1e-21
7300149 [T] KOG0578 p21-activated serine/threonine protein kinase 101 2e-21
YMR291w [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 101 2e-21
CE27899 [D] KOG0590 Checkpoint kinase and related serine/threoni... 100 3e-21
CE27177 [T] KOG4279 Serine/threonine protein kinase 100 3e-21
7298926 [T] KOG0578 p21-activated serine/threonine protein kinase 100 3e-21
HsM5454174 [T] KOG0201 Serine/threonine protein kinase 100 4e-21
Hs5453976 [T] KOG0694 Serine/threonine protein kinase 100 4e-21
Hs21361358 [T] KOG0201 Serine/threonine protein kinase 100 4e-21
ECU07g0520 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 100 4e-21
YHR102w [T] KOG0201 Serine/threonine protein kinase 100 5e-21
Hs14042947 [T] KOG0583 Serine/threonine protein kinase 100 5e-21
7301734 [T] KOG0694 Serine/threonine protein kinase 100 5e-21
7296166 [T] KOG0614 cGMP-dependent protein kinase 100 5e-21
7290841 [D] KOG0591 NIMA (never in mitosis)-related G2-specific ... 100 5e-21
CE27894_1 [R] KOG0589 Serine/threonine protein kinase 100 5e-21
YOL045w [T] KOG1152 Signal transduction serine/threonine kinase ... 100 7e-21
Hs4885583 [T] KOG0612 Rho-associated coiled-coil containing prot... 100 7e-21
Hs10835242 [T] KOG0614 cGMP-dependent protein kinase 100 7e-21
CE03492 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 100 7e-21
Hs4507277_1 [R] KOG0589 Serine/threonine protein kinase 100 7e-21
CE21239 [T] KOG0583 Serine/threonine protein kinase 99 9e-21
CE15235 [R] KOG0589 Serine/threonine protein kinase 99 9e-21
CE07599 [T] KOG0576 Mitogen-activated protein kinase kinase kina... 99 9e-21
At3g53930 [OUT] KOG0595 Serine/threonine-protein kinase involved... 99 9e-21
At3g17850 [TR] KOG0606 Microtubule-associated serine/threonine k... 99 9e-21
Hs4759044 [T] KOG0612 Rho-associated coiled-coil containing prot... 99 1e-20
Hs22066167 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 99 1e-20
Hs20536595 [T] KOG0612 Rho-associated coiled-coil containing pro... 99 1e-20
At3g20860 [R] KOG0589 Serine/threonine protein kinase 99 1e-20
7300413 [T] KOG0583 Serine/threonine protein kinase 99 1e-20
7297611 [T] KOG0614 cGMP-dependent protein kinase 99 1e-20
Hs5454094 [T] KOG0574 STE20-like serine/threonine kinase MST 99 2e-20
Hs4505373 [V] KOG1826 Ras GTPase activating protein RasGAP/neuro... 99 2e-20
Hs14754789 [OUT] KOG0595 Serine/threonine-protein kinase involve... 99 2e-20
7294537 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 99 2e-20
YDR466w [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 98 2e-20
Hs16178962 [T] KOG0574 STE20-like serine/threonine kinase MST 98 2e-20
Hs4505601 [T] KOG0578 p21-activated serine/threonine protein kinase 98 3e-20
7293249 [T] KOG0612 Rho-associated coiled-coil containing protei... 98 3e-20
Hs5454096 [T] KOG0574 STE20-like serine/threonine kinase MST 97 4e-20
Hs5453974 [T] KOG0694 Serine/threonine protein kinase 97 4e-20
ECU03g0620 [D] KOG0590 Checkpoint kinase and related serine/thre... 97 4e-20
CE01146 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 97 4e-20
At5g60550 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase k... 97 4e-20
At5g40440 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 97 4e-20
7297080 [T] KOG0583 Serine/threonine protein kinase 97 4e-20
Hs22068916 [T] KOG0696 Serine/threonine protein kinase 97 5e-20
Hs20127450 [T] KOG0696 Serine/threonine protein kinase 97 5e-20
Hs19424132 [D] KOG0591 NIMA (never in mitosis)-related G2-specif... 97 5e-20
CE28674 [T] KOG0201 Serine/threonine protein kinase 97 5e-20
CE26212 [T] KOG0582 Ste20-like serine/threonine protein kinase 97 5e-20
CE07510 [T] KOG0201 Serine/threonine protein kinase 97 5e-20
YCR008w [D] KOG0590 Checkpoint kinase and related serine/threoni... 97 6e-20
Hs4885563 [T] KOG0694 Serine/threonine protein kinase 97 6e-20
CE27670 [T] KOG0578 p21-activated serine/threonine protein kinase 97 6e-20
CE26076 [D] KOG0590 Checkpoint kinase and related serine/threoni... 97 6e-20
7293496 [R] KOG0597 Serine-threonine protein kinase FUSED 97 6e-20
YLR362w [T] KOG0198 MEKK and related serine/threonine protein ki... 96 8e-20
YCR073c [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and r... 96 8e-20
7301213 [R] KOG0589 Serine/threonine protein kinase 96 8e-20
YBR274w [D] KOG0590 Checkpoint kinase and related serine/threoni... 96 1e-19
SPBC12D12.04c [T] KOG0694 Serine/threonine protein kinase 96 1e-19
Hs9910476 [T] KOG0578 p21-activated serine/threonine protein kinase 96 1e-19
Hs6005810 [T] KOG0576 Mitogen-activated protein kinase kinase ki... 96 1e-19
CE20564 [T] KOG0578 p21-activated serine/threonine protein kinase 96 1e-19
CE05425 [T] KOG0578 p21-activated serine/threonine protein kinase 96 1e-19
Hs4506071 [T] KOG0695 Serine/threonine protein kinase 96 1e-19
Hs4505811 [T] KOG0583 Serine/threonine protein kinase 96 1e-19
SPAC890.03 [T] KOG0583 Serine/threonine protein kinase 95 2e-19
SPAC23H4.02 [T] KOG0583 Serine/threonine protein kinase 95 2e-19
Hs6031180 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and... 95 2e-19
Hs5803125 [T] KOG0583 Serine/threonine protein kinase 95 2e-19
Hs5803088 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and... 95 2e-19
CE18366 [T] KOG0583 Serine/threonine protein kinase 95 2e-19
At3g45240 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase k... 95 2e-19
At3g15220 [T] KOG0201 Serine/threonine protein kinase 95 2e-19
Hs22035600 [T] KOG0576 Mitogen-activated protein kinase kinase k... 95 2e-19
Hs17455844 [TR] KOG0606 Microtubule-associated serine/threonine ... 95 2e-19
Hs4506073 [T] KOG0694 Serine/threonine protein kinase 94 3e-19
Hs4504101 [T] KOG0986 G protein-coupled receptor kinase 94 3e-19
Hs14758219 [T] KOG0694 Serine/threonine protein kinase 94 3e-19
CE17354 [T] KOG0694 Serine/threonine protein kinase 94 3e-19
CE17353 [T] KOG0694 Serine/threonine protein kinase 94 3e-19
CE06686 [T] KOG0660 Mitogen-activated protein kinase 94 3e-19
CE02604 [T] KOG0695 Serine/threonine protein kinase 94 3e-19
At4g26890 [T] KOG0198 MEKK and related serine/threonine protein ... 94 3e-19
HsM4759010 [T] KOG0576 Mitogen-activated protein kinase kinase k... 94 4e-19
Hs4505153 [T] KOG0198 MEKK and related serine/threonine protein ... 94 4e-19
CE17343 [T] KOG0583 Serine/threonine protein kinase 94 4e-19
At1g53165 [T] KOG0201 Serine/threonine protein kinase 94 4e-19
7304312 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 94 4e-19
SPAC2C4.14c [T] KOG0201 Serine/threonine protein kinase 94 5e-19
Hs7019543 [T] KOG0582 Ste20-like serine/threonine protein kinase 94 5e-19
Hs13649368 [T] KOG0583 Serine/threonine protein kinase 94 5e-19
Hs13384594 [T] KOG0696 Serine/threonine protein kinase 94 5e-19
>YOL016c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 447
Score = 509 bits (1312), Expect = e-144
Identities = 247/408 (60%), Positives = 313/408 (76%), Gaps = 4/408 (0%)
Query: 16 EEPEPVEGHKLTKLFNKVTGQPSSYVNKSDYIFGKTLGAGTFGVVRQARCISSGENXXXX 75
++PE + GH + K NK++GQP SYVN+++YIFG+TLGAG+FGVVRQAR +S+ E+
Sbjct: 17 QDPERLNGHPVAKFINKLSGQPESYVNRTNYIFGRTLGAGSFGVVRQARKLSTNEDVAIK 76
Query: 76 XXXXXXXXGQSVQLQMLYDELSILQQLNHPNIVRFKDWFESKEKFYIVTQLATGGELFDR 135
G +VQLQMLY+ELSILQ+L+HPNIV FKDWFESK+KFYIVTQLATGGELFDR
Sbjct: 77 ILLKKALQGNNVQLQMLYEELSILQKLSHPNIVSFKDWFESKDKFYIVTQLATGGELFDR 136
Query: 136 ILEKGKFCEVDAVFIVKQILQGVQYLHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIA 195
IL +GKF EVDAV I+ QIL V+Y+H +N+VHRDLKPEN+LY++KS++SPLVI DFGIA
Sbjct: 137 ILSRGKFTEVDAVEIIVQILGAVEYMHSKNVVHRDLKPENVLYVDKSENSPLVIADFGIA 196
Query: 196 KELKDDNELIHKAAGSMGYVAPEVLTSSGHGKPCDIWSIGVITYTLLCGYSPFLAESADG 255
K+LK + +LI+KAAGS+GYVAPEVLT GHGKPCDIWSIGVITYTLLCGYSPF+AES +G
Sbjct: 197 KQLKGEEDLIYKAAGSLGYVAPEVLTQDGHGKPCDIWSIGVITYTLLCGYSPFIAESVEG 256
Query: 256 FIEECTSGQYPVVFHKPYWNNVSKTAKEFILWALTVSPKRRPTATDLINDIWITSTEKST 315
F+EECT+ +YPV FH PYW+N+S K FIL AL ++P RPTAT+L++D WITS T
Sbjct: 257 FMEECTASRYPVTFHMPYWDNISIDVKRFILKALRLNPADRPTATELLDDPWITSKRVET 316
Query: 316 TDLLPEIRKGFDARKEFRDAVEIVKLNNRIKKLKVLYENQDESDTDIEVNSTDSFSKNDY 375
+++LP+++KGF RK+ RDA+EIVKLNNRIK+L+ +Y D+ D DIE NS + +
Sbjct: 317 SNILPDVKKGFSLRKKLRDAIEIVKLNNRIKRLRNMYSLGDDGDNDIEENSLNESLLDGV 376
Query: 376 XXXXXXXXXXXXXXXXXHTE----LKSSLTQNAFAQLVLTASKNKEKV 419
TE LKS+LT++AF Q+V A+KNK KV
Sbjct: 377 THSLDDLRLQSQKKGGELTEEQMKLKSALTKDAFVQIVKAATKNKHKV 424
>YFR014c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 446
Score = 461 bits (1185), Expect = e-129
Identities = 233/412 (56%), Positives = 291/412 (70%), Gaps = 4/412 (0%)
Query: 7 LSENNSRKPEEPEPVEGHKLTKLFNKVTGQPSSYVNKSDYIFGKTLGAGTFGVVRQARCI 66
+ + S K P+ E K+ + QP+SYVNK Y+FGKTLGAGTFGVVRQA+
Sbjct: 1 MDDKVSEKESSPKQTEEDSEGKMAHV---QPASYVNKKKYVFGKTLGAGTFGVVRQAKNT 57
Query: 67 SSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNHPNIVRFKDWFESKEKFYIVTQL 126
+GE+ G VQL+ LYDEL ILQ+L+HPNIV FKDWFESK+KFYI+TQL
Sbjct: 58 ETGEDVAVKILIKKALKGNKVQLEALYDELDILQRLHHPNIVAFKDWFESKDKFYIITQL 117
Query: 127 ATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRNIVHRDLKPENILYLNKSDDSP 186
A GGELFDRIL+KGKF E DAV I+ +IL V+Y+H +NIVHRDLKPEN+LY++KSD+SP
Sbjct: 118 AKGGELFDRILKKGKFTEEDAVRILVEILSAVKYMHSQNIVHRDLKPENLLYIDKSDESP 177
Query: 187 LVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSGHGKPCDIWSIGVITYTLLCGYS 246
LV+ DFGIAK LK D EL++K AGS+GYVAPEVLT GHGKPCDIWSIGVITYTLLCGYS
Sbjct: 178 LVVADFGIAKRLKSDEELLYKPAGSLGYVAPEVLTQDGHGKPCDIWSIGVITYTLLCGYS 237
Query: 247 PFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKEFILWALTVSPKRRPTATDLINDI 306
F AE F++ECT+G+YPV FH+PYW++VS AK+FIL AL + P +RPTA +L+ D
Sbjct: 238 AFRAERVQDFLDECTTGEYPVKFHRPYWDSVSNKAKQFILKALNLDPSKRPTAAELLEDP 297
Query: 307 WITSTEKSTTDLLPEIRKGFDARKEFRDAVEIVKLNNRIKKLKVLYENQDESDTDIEVNS 366
WI TE T +LLP +++G DAR++FR++VE V+LN +I+KL+ LY Q ESD+D + S
Sbjct: 298 WIICTELKTHNLLPGLKEGLDARQKFRNSVERVRLNMKIQKLRDLYLEQTESDSDFDEGS 357
Query: 367 TDSFSKNDYXXXXXXXXXXXXXXXXXHTELKSSLTQNAFAQLVLTASKNKEK 418
+ S ++LKS LT AFAQLV T KEK
Sbjct: 358 QANGSVPP-LKATDTSQLSKKLSEEEQSKLKSELTSKAFAQLVNTVLAEKEK 408
>SPACUNK12.02c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 335
Score = 231 bits (588), Expect = 2e-60
Identities = 127/323 (39%), Positives = 190/323 (58%), Gaps = 13/323 (4%)
Query: 35 GQPSSYVNKSD-----YIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQL 89
G P + V++ Y G+ LG GT+ VR+A I + + +
Sbjct: 15 GAPKATVDQKQLLPCKYRVGRVLGGGTYATVREAVHIETNKMYAAKIMNKKMMEKKQ--- 71
Query: 90 QMLYDELSILQQLN--HPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDA 147
+ +E++IL++++ HPNI+ D+FE+ Y++T+LATGGELFDRI KG F E DA
Sbjct: 72 DFVKNEIAILKRVSYEHPNILHLVDFFETVNNLYLITELATGGELFDRICAKGSFYEADA 131
Query: 148 VFIVKQILQGVQYLHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDN-ELIH 206
+++ V+YLH IVHRDLKPEN+LY +K +S L+I DFG++ +D ++
Sbjct: 132 AALMRTTTSAVKYLHDNGIVHRDLKPENLLYRSKDPNSDLLIADFGLSHFYEDSQYYMLM 191
Query: 207 KAAGSMGYVAPEVLTSSGHGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYP 266
A G+ Y+APEV +G+GKP D+W+IGVITY LL GY+PF S IE + +Y
Sbjct: 192 TACGTPEYMAPEVFRRTGYGKPVDMWAIGVITYFLLSGYTPFARPSQVEVIEAILANEY- 250
Query: 267 VVFHKPYWNNVSKTAKEFILWALTVSPKRRPTATDLINDIWITSTEKSTTDLLPEIRKGF 326
F+ P W+ +S+TAK+FI L P +R TA D + +++ +T++LLP +R+ F
Sbjct: 251 -TFNDPCWSGISETAKDFIKKCLENDPSKRLTAADALKHPFLSEKRPATSNLLPNVRENF 309
Query: 327 DARKEFRDAVEIVKLNNRIKKLK 349
+ARK FR A V+ N KKL+
Sbjct: 310 NARKTFRTAYNAVRAFNTWKKLE 332
>Hs14196445 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 476
Score = 216 bits (551), Expect = 4e-56
Identities = 118/310 (38%), Positives = 178/310 (57%), Gaps = 13/310 (4%)
Query: 43 KSDYIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQL 102
+ +IF + LG+G F V + +G+ S L +E+++L+++
Sbjct: 20 RKTFIFMEVLGSGAFSEVFLVKQRLTGKLFALKCIKKSPAFRDS----SLENEIAVLKKI 75
Query: 103 NHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLH 162
H NIV +D +ES +Y+V QL +GGELFDRILE+G + E DA +++Q+L V+YLH
Sbjct: 76 KHENIVTLEDIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVKYLH 135
Query: 163 QRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTS 222
+ IVHRDLKPEN+LYL ++S ++I DFG++K + N ++ A G+ GYVAPEVL
Sbjct: 136 ENGIVHRDLKPENLLYLTPEENSKIMITDFGLSK--MEQNGIMSTACGTPGYVAPEVLAQ 193
Query: 223 SGHGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAK 282
+ K D WSIGVITY LLCGY PF E+ E+ G Y F P+W+++S++AK
Sbjct: 194 KPYSKAVDCWSIGVITYILLCGYPPFYEETESKLFEKIKEGYYE--FESPFWDDISESAK 251
Query: 283 EFILWALTVSPKRRPTATDLINDIWITSTEKSTTDLLP----EIRKGFDARKEFRDAVEI 338
+FI L P R T ++ WI D+ P +I+K F A+ ++R A
Sbjct: 252 DFICHLLEKDPNERYTCEKALSHPWIDGNTALHRDIYPSVSLQIQKNF-AKSKWRQAFNA 310
Query: 339 VKLNNRIKKL 348
+ + ++KL
Sbjct: 311 AAVVHHMRKL 320
>7304311 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 405
Score = 211 bits (537), Expect = 2e-54
Identities = 112/283 (39%), Positives = 165/283 (57%), Gaps = 23/283 (8%)
Query: 52 LGAGTFGVVRQARCISS-GENXXXXXXXXXXXXGQSVQLQMLYDELSILQQ--------- 101
LG G F VR A S GE+ G+ L+ +E+ +L++
Sbjct: 37 LGTGAFSEVRLAESKDSPGEHFAVKIIDKKALKGKEESLE---NEIRVLRRFSANHFDGK 93
Query: 102 ------LNHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQIL 155
L HPNIV+ + +E K K Y+V +L TGGELFDRI+EKG + E DA +++QIL
Sbjct: 94 CLNGTRLTHPNIVQLLETYEDKSKVYLVMELVTGGELFDRIVEKGSYTEKDASHLIRQIL 153
Query: 156 QGVQYLHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYV 215
+ V Y+H++ +VHRDLKPEN+LY + DDS ++I DFG++K +D+ ++ A G+ GYV
Sbjct: 154 EAVDYMHEQGVVHRDLKPENLLYYSPDDDSKIMISDFGLSK--MEDSGIMATACGTPGYV 211
Query: 216 APEVLTSSGHGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWN 275
APEVL +GK D+WSIGVI+Y LLCGY PF E+ + G + F PYW+
Sbjct: 212 APEVLAQKPYGKAVDVWSIGVISYILLCGYPPFYDENDANLFAQILKGDFE--FDSPYWD 269
Query: 276 NVSKTAKEFILWALTVSPKRRPTATDLINDIWITSTEKSTTDL 318
+S++AK FI + V+ ++R T + WI+ E S+ ++
Sbjct: 270 EISESAKHFIKNLMCVTVEKRYTCKQALGHAWISGNEASSRNI 312
>CE25046 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 348
Score = 211 bits (536), Expect = 2e-54
Identities = 110/277 (39%), Positives = 162/277 (57%), Gaps = 8/277 (2%)
Query: 43 KSDYIFGKTLGAGTFGVVRQARCIS-SGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQ 101
+ Y F LG G F V A S +G+ G+ L+ +E+ +L++
Sbjct: 19 REKYDFRDVLGTGAFSKVFLAESKSDAGQMYAVKCIDKKALKGKEESLE---NEIKVLRK 75
Query: 102 LNHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYL 161
L H NIV+ D ++ K+ Y+V +L TGGELFDRI+ KG + E DA +++Q+L+ V ++
Sbjct: 76 LRHNNIVQLFDTYDEKQFVYLVMELVTGGELFDRIVAKGSYTEQDASNLIRQVLEAVGFM 135
Query: 162 HQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLT 221
H +VHRDLKPEN+LY N+ +DS ++I DFG++K +D+ ++ A G+ GYVAPEVL
Sbjct: 136 HDNGVVHRDLKPENLLYYNQDEDSKIMISDFGLSK--TEDSGVMATACGTPGYVAPEVLQ 193
Query: 222 SSGHGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTA 281
+GK D+WSIGVI Y LLCGY PF ES + G+Y F PYW+ +S +A
Sbjct: 194 QKPYGKAVDVWSIGVIAYILLCGYPPFYDESDANLFAQIIKGEYE--FDAPYWDQISDSA 251
Query: 282 KEFILWALTVSPKRRPTATDLINDIWITSTEKSTTDL 318
K+FI + P+ R T D ++ WI+ T D+
Sbjct: 252 KDFITHLMCCDPEARFTCQDALSHPWISGNTAYTHDI 288
>Hs9966875 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 357
Score = 209 bits (531), Expect = 8e-54
Identities = 119/324 (36%), Positives = 185/324 (56%), Gaps = 12/324 (3%)
Query: 43 KSDYIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQL 102
K + F +TLG G F V A ++G+ G+ ++ +E+++L+++
Sbjct: 20 KKIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKESSIE---NEIAVLRKI 76
Query: 103 NHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLH 162
H NIV +D +ES Y+V QL +GGELFDRI+EKG + E DA +++Q+L V YLH
Sbjct: 77 KHENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLH 136
Query: 163 QRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTS 222
+ IVHRDLKPEN+LY ++ ++S ++I DFG++K ++ +++ A G+ GYVAPEVL
Sbjct: 137 RMGIVHRDLKPENLLYYSQDEESKIMISDFGLSK-MEGKGDVMSTACGTPGYVAPEVLAQ 195
Query: 223 SGHGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAK 282
+ K D WSIGVI Y LLCGY PF E+ E+ +Y F PYW+++S +AK
Sbjct: 196 KPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYE--FDSPYWDDISDSAK 253
Query: 283 EFILWALTVSPKRRPTATDLINDIWI---TSTEKSTTD-LLPEIRKGFDARKEFRDAVEI 338
+FI + P +R T WI T+ K+ + + +IRK F A+ ++R A
Sbjct: 254 DFIRNLMEKDPNKRYTCEQAARHPWIAGDTALNKNIHESVSAQIRKNF-AKSKWRQAFNA 312
Query: 339 VKLNNRIKKLKVLYENQDESDTDI 362
+ ++KL L + D S+ +
Sbjct: 313 TAVVRHMRKLH-LGSSLDSSNASV 335
>Hs4502553 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 370
Score = 205 bits (522), Expect = 9e-53
Identities = 116/319 (36%), Positives = 178/319 (55%), Gaps = 11/319 (3%)
Query: 46 YIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNHP 105
Y F LG G F V A + + G+ ++ +E+++L ++ HP
Sbjct: 20 YDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAKEALEGKEGSME---NEIAVLHKIKHP 76
Query: 106 NIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRN 165
NIV D +ES Y++ QL +GGELFDRI+EKG + E DA ++ Q+L V+YLH
Sbjct: 77 NIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLG 136
Query: 166 IVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSGH 225
IVHRDLKPEN+LY + +DS ++I DFG++K ++D ++ A G+ GYVAPEVL +
Sbjct: 137 IVHRDLKPENLLYYSLDEDSKIMISDFGLSK-MEDPGSVLSTACGTPGYVAPEVLAQKPY 195
Query: 226 GKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKEFI 285
K D WSIGVI Y LLCGY PF E+ E+ +Y F PYW+++S +AK+FI
Sbjct: 196 SKAVDCWSIGVIAYILLCGYPPFYDENDAKLFEQILKAEYE--FDSPYWDDISDSAKDFI 253
Query: 286 LWALTVSPKRRPTATDLINDIWI---TSTEKSTTDLLPE-IRKGFDARKEFRDAVEIVKL 341
+ P++R T + WI T+ +K+ + E I+K F A+ +++ A +
Sbjct: 254 RHLMEKDPEKRFTCEQALQHPWIAGDTALDKNIHQSVSEQIKKNF-AKSKWKQAFNATAV 312
Query: 342 NNRIKKLKVLYENQDESDT 360
++KL++ + + T
Sbjct: 313 VRHMRKLQLGTSQEGQGQT 331
>Hs4502557 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 473
Score = 202 bits (513), Expect = 1e-51
Identities = 104/264 (39%), Positives = 162/264 (60%), Gaps = 6/264 (2%)
Query: 85 QSVQLQMLYDELSILQQLNHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCE 144
++V +++ E+ +L +L+HPNI++ K+ FE+ + +V +L TGGELFDRI+EKG + E
Sbjct: 79 KTVDKKIVRTEIGVLLRLSHPNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSE 138
Query: 145 VDAVFIVKQILQGVQYLHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNEL 204
DA VKQIL+ V YLH+ IVHRDLKPEN+LY + D+PL I DFG++K + + L
Sbjct: 139 RDAADAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPDAPLKIADFGLSK-IVEHQVL 197
Query: 205 IHKAAGSMGYVAPEVLTSSGHGKPCDIWSIGVITYTLLCGYSPFLAESADGFI-EECTSG 263
+ G+ GY APE+L +G D+WS+G+ITY LLCG+ PF E D F+ +
Sbjct: 198 MKTVCGTPGYCAPEILRGCAYGPEVDMWSVGIITYILLCGFEPFYDERGDQFMFRRILNC 257
Query: 264 QYPVVFHKPYWNNVSKTAKEFILWALTVSPKRRPTATDLINDIWITSTEKSTT--DLLPE 321
+Y F P+W+ VS AK+ + + + PK+R T + W+T + D +
Sbjct: 258 EY--YFISPWWDEVSLNAKDLVRKLIVLDPKKRLTTFQALQHPWVTGKAANFVHMDTAQK 315
Query: 322 IRKGFDARKEFRDAVEIVKLNNRI 345
+ F+AR++ + AV+ V ++R+
Sbjct: 316 KLQEFNARRKLKAAVKAVVASSRL 339
>CE28058 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 571
Score = 190 bits (482), Expect = 4e-48
Identities = 111/305 (36%), Positives = 163/305 (53%), Gaps = 9/305 (2%)
Query: 45 DYIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNH 104
+Y + LG G F VVR RC+ + Q L E I ++L H
Sbjct: 11 NYDVKEELGKGAFSVVR--RCVHKTTGLEFAAKIINTKKLSARDFQKLEREARICRKLQH 68
Query: 105 PNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQR 164
PNIVR D + + Y+V L TGGELF+ I+ + + E DA ++QIL+ + Y H
Sbjct: 69 PNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESIAYCHSN 128
Query: 165 NIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSG 224
IVHRDLKPEN+L +K+ + + + DFG+A E+ +D+E H AG+ GY++PEVL
Sbjct: 129 GIVHRDLKPENLLLASKAKGAAVKLADFGLAIEV-NDSEAWHGFAGTPGYLSPEVLKKDP 187
Query: 225 HGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKEF 284
+ KP DIW+ GVI Y LL GY PF E + +G Y + P W+ V+ AK
Sbjct: 188 YSKPVDIWACGVILYILLVGYPPFWDEDQHRLYAQIKAGAYD--YPSPEWDTVTPEAKSL 245
Query: 285 ILWALTVSPKRRPTATDLINDIWITSTEKSTTDL----LPEIRKGFDARKEFRDAVEIVK 340
I LTV+PK+R TA + WI + E+ + + + K F+AR++ + A+ VK
Sbjct: 246 IDSMLTVNPKKRITADQALKVPWICNRERVASAIHRQDTVDCLKKFNARRKLKAAISAVK 305
Query: 341 LNNRI 345
+ R+
Sbjct: 306 MVTRM 310
>CE28055 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 533
Score = 190 bits (482), Expect = 4e-48
Identities = 111/305 (36%), Positives = 163/305 (53%), Gaps = 9/305 (2%)
Query: 45 DYIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNH 104
+Y + LG G F VVR RC+ + Q L E I ++L H
Sbjct: 11 NYDVKEELGKGAFSVVR--RCVHKTTGLEFAAKIINTKKLSARDFQKLEREARICRKLQH 68
Query: 105 PNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQR 164
PNIVR D + + Y+V L TGGELF+ I+ + + E DA ++QIL+ + Y H
Sbjct: 69 PNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESIAYCHSN 128
Query: 165 NIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSG 224
IVHRDLKPEN+L +K+ + + + DFG+A E+ +D+E H AG+ GY++PEVL
Sbjct: 129 GIVHRDLKPENLLLASKAKGAAVKLADFGLAIEV-NDSEAWHGFAGTPGYLSPEVLKKDP 187
Query: 225 HGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKEF 284
+ KP DIW+ GVI Y LL GY PF E + +G Y + P W+ V+ AK
Sbjct: 188 YSKPVDIWACGVILYILLVGYPPFWDEDQHRLYAQIKAGAYD--YPSPEWDTVTPEAKSL 245
Query: 285 ILWALTVSPKRRPTATDLINDIWITSTEKSTTDL----LPEIRKGFDARKEFRDAVEIVK 340
I LTV+PK+R TA + WI + E+ + + + K F+AR++ + A+ VK
Sbjct: 246 IDSMLTVNPKKRITADQALKVPWICNRERVASAIHRQDTVDCLKKFNARRKLKAAISAVK 305
Query: 341 LNNRI 345
+ R+
Sbjct: 306 MVTRM 310
>CE28053 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 720
Score = 190 bits (482), Expect = 4e-48
Identities = 111/305 (36%), Positives = 163/305 (53%), Gaps = 9/305 (2%)
Query: 45 DYIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNH 104
+Y + LG G F VVR RC+ + Q L E I ++L H
Sbjct: 11 NYDVKEELGKGAFSVVR--RCVHKTTGLEFAAKIINTKKLSARDFQKLEREARICRKLQH 68
Query: 105 PNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQR 164
PNIVR D + + Y+V L TGGELF+ I+ + + E DA ++QIL+ + Y H
Sbjct: 69 PNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESIAYCHSN 128
Query: 165 NIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSG 224
IVHRDLKPEN+L +K+ + + + DFG+A E+ +D+E H AG+ GY++PEVL
Sbjct: 129 GIVHRDLKPENLLLASKAKGAAVKLADFGLAIEV-NDSEAWHGFAGTPGYLSPEVLKKDP 187
Query: 225 HGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKEF 284
+ KP DIW+ GVI Y LL GY PF E + +G Y + P W+ V+ AK
Sbjct: 188 YSKPVDIWACGVILYILLVGYPPFWDEDQHRLYAQIKAGAYD--YPSPEWDTVTPEAKSL 245
Query: 285 ILWALTVSPKRRPTATDLINDIWITSTEKSTTDL----LPEIRKGFDARKEFRDAVEIVK 340
I LTV+PK+R TA + WI + E+ + + + K F+AR++ + A+ VK
Sbjct: 246 IDSMLTVNPKKRITADQALKVPWICNRERVASAIHRQDTVDCLKKFNARRKLKAAISAVK 305
Query: 341 LNNRI 345
+ R+
Sbjct: 306 MVTRM 310
>Hs14141724 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 499
Score = 188 bits (478), Expect = 1e-47
Identities = 117/335 (34%), Positives = 172/335 (50%), Gaps = 24/335 (7%)
Query: 45 DYIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNH 104
+Y + LG G F VVR+ I +G+ + Q L E I + L H
Sbjct: 13 EYQLFEELGKGAFSVVRRCMKIPTGQGYAAKIINTKKLSARDHQ--KLEREARICRLLKH 70
Query: 105 PNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQR 164
PNIVR D + Y+V L TGGELF+ I+ + + E DA ++QIL+ V + H
Sbjct: 71 PNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLN 130
Query: 165 NIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSG 224
IVHRDLKPEN+L +KS + + + DFG+A E++ D + AG+ GY++PEVL
Sbjct: 131 GIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDP 190
Query: 225 HGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKEF 284
+GKP D+W+ GVI Y LL GY PF E ++ +G Y F P W+ V+ AK+
Sbjct: 191 YGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYD--FPSPEWDTVTPEAKDL 248
Query: 285 ILWALTVSPKRRPTATDLINDIWITST--------EKSTTDLLPEIRKGFDARKEFRDAV 336
I LT++P +R TA++ + WI + T D L K F+AR++ + A+
Sbjct: 249 INKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCL----KKFNARRKLKGAI 304
Query: 337 EIVKLNNR--------IKKLKVLYENQDESDTDIE 363
L R +KK + E+ + S+T IE
Sbjct: 305 LTTMLATRNFSAAKSLLKKPDGVKESTESSNTTIE 339
>7304358 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 493
Score = 187 bits (474), Expect = 3e-47
Identities = 111/317 (35%), Positives = 164/317 (51%), Gaps = 17/317 (5%)
Query: 37 PSSYVNKSD-YIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDE 95
P++ SD Y + LG G F +V+ RC+ + Q L E
Sbjct: 4 PAACTRFSDNYDIKEELGKGAFSIVK--RCVQKSTGFEFAAKIINTKKLTARDFQKLERE 61
Query: 96 LSILQQLNHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQIL 155
I ++L+HPNIVR D + + Y+V L TGGELF+ I+ + + E DA ++QIL
Sbjct: 62 ARICRKLHHPNIVRLHDSIQEENYHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQIL 121
Query: 156 QGVQYLHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYV 215
+ V + HQ +VHRDLKPEN+L +K+ + + + DFG+A E++ D++ AG+ GY+
Sbjct: 122 ESVNHCHQNGVVHRDLKPENLLLASKAKGAAVKLADFGLAIEVQGDHQAWFGFAGTPGYL 181
Query: 216 APEVLTSSGHGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWN 275
+PEVL +GK DIW+ GVI Y LL GY PF E + +G Y + P W+
Sbjct: 182 SPEVLKKEPYGKSVDIWACGVILYILLVGYPPFWDEDQHRLYSQIKAGAYD--YPSPEWD 239
Query: 276 NVSKTAKEFILWALTVSPKRRPTATDLINDIWITSTEK--------STTDLLPEIRKGFD 327
V+ AK I LTV+P +R TA + + WI E+ T D L K F+
Sbjct: 240 TVTPEAKNLINQMLTVNPNKRITAAEALKHPWICQRERVASVVHRQETVDCL----KKFN 295
Query: 328 ARKEFRDAVEIVKLNNR 344
AR++ + A+ L R
Sbjct: 296 ARRKLKGAILTTMLATR 312
>CE28056 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 518
Score = 186 bits (473), Expect = 4e-47
Identities = 112/329 (34%), Positives = 169/329 (51%), Gaps = 9/329 (2%)
Query: 45 DYIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNH 104
+Y + LG G F VVR RC+ + Q L E I ++L H
Sbjct: 11 NYDVKEELGKGAFSVVR--RCVHKTTGLEFAAKIINTKKLSARDFQKLEREARICRKLQH 68
Query: 105 PNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQR 164
PNIVR D + + Y+V L TGGELF+ I+ + + E DA ++QIL+ + Y H
Sbjct: 69 PNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESIAYCHSN 128
Query: 165 NIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSG 224
IVHRDLKPEN+L +K+ + + + DFG+A E+ +D+E H AG+ GY++PEVL
Sbjct: 129 GIVHRDLKPENLLLASKAKGAAVKLADFGLAIEV-NDSEAWHGFAGTPGYLSPEVLKKDP 187
Query: 225 HGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKEF 284
+ KP DIW+ GVI Y LL GY PF E + +G Y + P W+ V+ AK
Sbjct: 188 YSKPVDIWACGVILYILLVGYPPFWDEDQHRLYAQIKAGAYD--YPSPEWDTVTPEAKSL 245
Query: 285 ILWALTVSPKRRPTATDLINDIWITSTEKSTTDL----LPEIRKGFDARKEFRDAVEIVK 340
I LTV+PK+R TA + WI + E+ + + + K F+AR++ + A+
Sbjct: 246 IDSMLTVNPKKRITADQALKVPWICNRERVASAIHRQDTVDCLKKFNARRKLKGAILTTM 305
Query: 341 LNNRIKKLKVLYENQDESDTDIEVNSTDS 369
+ R + L +++ S++S
Sbjct: 306 IATRNLSSRNLLNKKEQGPPSTIKESSES 334
>CE28059 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 350
Score = 185 bits (470), Expect = 1e-46
Identities = 108/296 (36%), Positives = 158/296 (52%), Gaps = 9/296 (3%)
Query: 45 DYIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNH 104
+Y + LG G F VVR RC+ + Q L E I ++L H
Sbjct: 11 NYDVKEELGKGAFSVVR--RCVHKTTGLEFAAKIINTKKLSARDFQKLEREARICRKLQH 68
Query: 105 PNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQR 164
PNIVR D + + Y+V L TGGELF+ I+ + + E DA ++QIL+ + Y H
Sbjct: 69 PNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESIAYCHSN 128
Query: 165 NIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSG 224
IVHRDLKPEN+L +K+ + + + DFG+A E+ +D+E H AG+ GY++PEVL
Sbjct: 129 GIVHRDLKPENLLLASKAKGAAVKLADFGLAIEV-NDSEAWHGFAGTPGYLSPEVLKKDP 187
Query: 225 HGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKEF 284
+ KP DIW+ GVI Y LL GY PF E + +G Y + P W+ V+ AK
Sbjct: 188 YSKPVDIWACGVILYILLVGYPPFWDEDQHRLYAQIKAGAYD--YPSPEWDTVTPEAKSL 245
Query: 285 ILWALTVSPKRRPTATDLINDIWITSTEKSTTDL----LPEIRKGFDARKEFRDAV 336
I LTV+PK+R TA + WI + E+ + + + K F+AR++ + A+
Sbjct: 246 IDSMLTVNPKKRITADQALKVPWICNRERVASAIHRQDTVDCLKKFNARRKLKGAI 301
>CE28057 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 520
Score = 185 bits (470), Expect = 1e-46
Identities = 108/296 (36%), Positives = 158/296 (52%), Gaps = 9/296 (3%)
Query: 45 DYIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNH 104
+Y + LG G F VVR RC+ + Q L E I ++L H
Sbjct: 11 NYDVKEELGKGAFSVVR--RCVHKTTGLEFAAKIINTKKLSARDFQKLEREARICRKLQH 68
Query: 105 PNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQR 164
PNIVR D + + Y+V L TGGELF+ I+ + + E DA ++QIL+ + Y H
Sbjct: 69 PNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESIAYCHSN 128
Query: 165 NIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSG 224
IVHRDLKPEN+L +K+ + + + DFG+A E+ +D+E H AG+ GY++PEVL
Sbjct: 129 GIVHRDLKPENLLLASKAKGAAVKLADFGLAIEV-NDSEAWHGFAGTPGYLSPEVLKKDP 187
Query: 225 HGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKEF 284
+ KP DIW+ GVI Y LL GY PF E + +G Y + P W+ V+ AK
Sbjct: 188 YSKPVDIWACGVILYILLVGYPPFWDEDQHRLYAQIKAGAYD--YPSPEWDTVTPEAKSL 245
Query: 285 ILWALTVSPKRRPTATDLINDIWITSTEKSTTDL----LPEIRKGFDARKEFRDAV 336
I LTV+PK+R TA + WI + E+ + + + K F+AR++ + A+
Sbjct: 246 IDSMLTVNPKKRITADQALKVPWICNRERVASAIHRQDTVDCLKKFNARRKLKGAI 301
>CE28054 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 482
Score = 185 bits (470), Expect = 1e-46
Identities = 108/296 (36%), Positives = 158/296 (52%), Gaps = 9/296 (3%)
Query: 45 DYIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNH 104
+Y + LG G F VVR RC+ + Q L E I ++L H
Sbjct: 11 NYDVKEELGKGAFSVVR--RCVHKTTGLEFAAKIINTKKLSARDFQKLEREARICRKLQH 68
Query: 105 PNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQR 164
PNIVR D + + Y+V L TGGELF+ I+ + + E DA ++QIL+ + Y H
Sbjct: 69 PNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESIAYCHSN 128
Query: 165 NIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSG 224
IVHRDLKPEN+L +K+ + + + DFG+A E+ +D+E H AG+ GY++PEVL
Sbjct: 129 GIVHRDLKPENLLLASKAKGAAVKLADFGLAIEV-NDSEAWHGFAGTPGYLSPEVLKKDP 187
Query: 225 HGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKEF 284
+ KP DIW+ GVI Y LL GY PF E + +G Y + P W+ V+ AK
Sbjct: 188 YSKPVDIWACGVILYILLVGYPPFWDEDQHRLYAQIKAGAYD--YPSPEWDTVTPEAKSL 245
Query: 285 ILWALTVSPKRRPTATDLINDIWITSTEKSTTDL----LPEIRKGFDARKEFRDAV 336
I LTV+PK+R TA + WI + E+ + + + K F+AR++ + A+
Sbjct: 246 IDSMLTVNPKKRITADQALKVPWICNRERVASAIHRQDTVDCLKKFNARRKLKGAI 301
>CE28051 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 559
Score = 185 bits (470), Expect = 1e-46
Identities = 108/296 (36%), Positives = 158/296 (52%), Gaps = 9/296 (3%)
Query: 45 DYIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNH 104
+Y + LG G F VVR RC+ + Q L E I ++L H
Sbjct: 11 NYDVKEELGKGAFSVVR--RCVHKTTGLEFAAKIINTKKLSARDFQKLEREARICRKLQH 68
Query: 105 PNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQR 164
PNIVR D + + Y+V L TGGELF+ I+ + + E DA ++QIL+ + Y H
Sbjct: 69 PNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESIAYCHSN 128
Query: 165 NIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSG 224
IVHRDLKPEN+L +K+ + + + DFG+A E+ +D+E H AG+ GY++PEVL
Sbjct: 129 GIVHRDLKPENLLLASKAKGAAVKLADFGLAIEV-NDSEAWHGFAGTPGYLSPEVLKKDP 187
Query: 225 HGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKEF 284
+ KP DIW+ GVI Y LL GY PF E + +G Y + P W+ V+ AK
Sbjct: 188 YSKPVDIWACGVILYILLVGYPPFWDEDQHRLYAQIKAGAYD--YPSPEWDTVTPEAKSL 245
Query: 285 ILWALTVSPKRRPTATDLINDIWITSTEKSTTDL----LPEIRKGFDARKEFRDAV 336
I LTV+PK+R TA + WI + E+ + + + K F+AR++ + A+
Sbjct: 246 IDSMLTVNPKKRITADQALKVPWICNRERVASAIHRQDTVDCLKKFNARRKLKGAI 301
>CE28060 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 302
Score = 185 bits (469), Expect = 1e-46
Identities = 111/307 (36%), Positives = 160/307 (51%), Gaps = 17/307 (5%)
Query: 45 DYIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNH 104
+Y + LG G F VVR RC+ + Q L E I ++L H
Sbjct: 11 NYDVKEELGKGAFSVVR--RCVHKTTGLEFAAKIINTKKLSARDFQKLEREARICRKLQH 68
Query: 105 PNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQR 164
PNIVR D + + Y+V L TGGELF+ I+ + + E DA ++QIL+ + Y H
Sbjct: 69 PNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESIAYCHSN 128
Query: 165 NIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSG 224
IVHRDLKPEN+L +K+ + + + DFG+A E+ +D+E H AG+ GY++PEVL
Sbjct: 129 GIVHRDLKPENLLLASKAKGAAVKLADFGLAIEV-NDSEAWHGFAGTPGYLSPEVLKKDP 187
Query: 225 HGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKEF 284
+ KP DIW+ GVI Y LL GY PF E + +G Y + P W+ V+ AK
Sbjct: 188 YSKPVDIWACGVILYILLVGYPPFWDEDQHRLYAQIKAGAYD--YPSPEWDTVTPEAKSL 245
Query: 285 ILWALTVSPKRRPTATDLINDIWITSTEKSTTDLLPEIRKGFDARKEFRDAVEIVKLNNR 344
I LTV+PK+R TA + WI + E+ + + +D V+ +K N
Sbjct: 246 IDSMLTVNPKKRITADQALKVPWICNRERVASAI------------HRQDTVDCLKKFNA 293
Query: 345 IKKLKVL 351
+KLKV+
Sbjct: 294 RRKLKVV 300
>CE28061 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 302
Score = 184 bits (468), Expect = 2e-46
Identities = 108/296 (36%), Positives = 158/296 (52%), Gaps = 9/296 (3%)
Query: 45 DYIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNH 104
+Y + LG G F VVR RC+ + Q L E I ++L H
Sbjct: 11 NYDVKEELGKGAFSVVR--RCVHKTTGLEFAAKIINTKKLSARDFQKLEREARICRKLQH 68
Query: 105 PNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQR 164
PNIVR D + + Y+V L TGGELF+ I+ + + E DA ++QIL+ + Y H
Sbjct: 69 PNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESIAYCHSN 128
Query: 165 NIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSG 224
IVHRDLKPEN+L +K+ + + + DFG+A E+ +D+E H AG+ GY++PEVL
Sbjct: 129 GIVHRDLKPENLLLASKAKGAAVKLADFGLAIEV-NDSEAWHGFAGTPGYLSPEVLKKDP 187
Query: 225 HGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKEF 284
+ KP DIW+ GVI Y LL GY PF E + +G Y + P W+ V+ AK
Sbjct: 188 YSKPVDIWACGVILYILLVGYPPFWDEDQHRLYAQIKAGAYD--YPSPEWDTVTPEAKSL 245
Query: 285 ILWALTVSPKRRPTATDLINDIWITSTEKSTTDL----LPEIRKGFDARKEFRDAV 336
I LTV+PK+R TA + WI + E+ + + + K F+AR++ + A+
Sbjct: 246 IDSMLTVNPKKRITADQALKVPWICNRERVASAIHRQDTVDCLKKFNARRKLKVAI 301
>Hs7706286 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 489
Score = 181 bits (460), Expect = 1e-45
Identities = 106/308 (34%), Positives = 160/308 (51%), Gaps = 16/308 (5%)
Query: 45 DYIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNH 104
+Y + LG G F VVR+ + +G+ + Q L E I + L H
Sbjct: 12 EYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQ--KLEREARICRLLKH 69
Query: 105 PNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQR 164
PNIVR D + Y++ L TGGELF+ I+ + + E DA ++QIL+ V + HQ
Sbjct: 70 PNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQM 129
Query: 165 NIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSG 224
+VHRDLKPEN+L +K + + + DFG+A E++ + + AG+ GY++PEVL
Sbjct: 130 GVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKDP 189
Query: 225 HGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKEF 284
+GKP D+W+ GVI Y LL GY PF E ++ +G Y F P W+ V+ AK+
Sbjct: 190 YGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYD--FPSPEWDTVTPEAKDL 247
Query: 285 ILWALTVSPKRRPTATDLINDIWITST--------EKSTTDLLPEIRKGFDARKEFRDAV 336
I LT++P +R TA + + WI+ + T D L K F+AR++ + A+
Sbjct: 248 INKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCL----KKFNARRKLKGAI 303
Query: 337 EIVKLNNR 344
L R
Sbjct: 304 LTTMLATR 311
>Hs4826684_1 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 370
Score = 180 bits (456), Expect = 4e-45
Identities = 112/334 (33%), Positives = 175/334 (51%), Gaps = 12/334 (3%)
Query: 46 YIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXG--QSVQLQMLYDELSILQQLN 103
Y G+ LG+G F VV++ R S+G + V + + E+SIL+++
Sbjct: 13 YDTGEELGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRRGVSREDIEREVSILKEIQ 72
Query: 104 HPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQ 163
HPN++ + +E+K ++ +L GGELFD + EK E +A +KQIL GV YLH
Sbjct: 73 HPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQILNGVYYLHS 132
Query: 164 RNIVHRDLKPENILYLNKSDDSPLV-IGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTS 222
I H DLKPENI+ L+++ P + I DFG+A ++ NE G+ +VAPE++
Sbjct: 133 LQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHKIDFGNE-FKNIFGTPEFVAPEIVNY 191
Query: 223 SGHGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAK 282
G D+WSIGVITY LL G SPFL ++ + ++ Y F Y++N S AK
Sbjct: 192 EPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANVSAVNYE--FEDEYFSNTSALAK 249
Query: 283 EFILWALTVSPKRRPTATDLINDIWI------TSTEKSTTDLLPEIRKGFDARKEFRDAV 336
+FI L PK+R T D + WI + + + + E K F ARK+++ +V
Sbjct: 250 DFIRRLLVKDPKKRMTIQDSLQHPWIKPKDTQQALSRKASAVNMEKFKKFAARKKWKQSV 309
Query: 337 EIVKLNNRIKKLKVLYENQDESDTDIEVNSTDSF 370
++ L R+ + + N + +D ++ DSF
Sbjct: 310 RLISLCQRLSRSFLSRSNMSVARSDDTLDEEDSF 343
>Hs14728804 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 576
Score = 179 bits (454), Expect = 7e-45
Identities = 108/317 (34%), Positives = 165/317 (51%), Gaps = 20/317 (6%)
Query: 3 KKEPLSENNSRKPEEPEPVEGHKLTKLFNKVTGQPSSYVNKSDYIFGKTLGAGTFGVVRQ 62
+KEP + KPE P G K + G ++ V K Y G+ +G G F VV++
Sbjct: 250 EKEPKTRPEENKPERPS---GRKPRPM-----GIIAANVEKH-YETGRVIGDGNFAVVKE 300
Query: 63 ARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNHPNIVRFKDWFESKEKFYI 122
R + + G+ M+ E+ I+Q L+HPNIV+ + +E+ + Y+
Sbjct: 301 CRHRETRQAYAMKIIDKSRLKGKE---DMVDSEILIIQSLSHPNIVKLHEVYETDMEIYL 357
Query: 123 VTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRNIVHRDLKPENILYLNKS 182
+ + GG+LFD I+E KF E DA ++ + + + ++H ++IVHRDLKPEN+L
Sbjct: 358 ILEYVQGGDLFDAIIESVKFPEPDAALMIMDLCKALVHMHDKSIVHRDLKPENLLVQRNE 417
Query: 183 DDS-PLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSGHGKPCDIWSIGVITYTL 241
D S L + DFG+AK + I G+ YVAPE+L+ G+G D+W+ GVI Y L
Sbjct: 418 DKSTTLKLADFGLAKHVV---RPIFTVCGTPTYVAPEILSEKGYGLEVDMWAAGVILYIL 474
Query: 242 LCGYSPFLA--ESADGFIEECTSGQYPVVFHKPYWNNVSKTAKEFILWALTVSPKRRPTA 299
LCG+ PF + D G + F PYW+N+S AK+ + L V PK+R TA
Sbjct: 475 LCGFPPFRSPERDQDELFNIIQLGHFE--FLPPYWDNISDAAKDLVSRLLVVDPKKRYTA 532
Query: 300 TDLINDIWITSTEKSTT 316
++ WI + K+ T
Sbjct: 533 HQVLQHPWIETAGKTNT 549
>Hs20127418 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 664
Score = 178 bits (451), Expect = 2e-44
Identities = 106/306 (34%), Positives = 158/306 (50%), Gaps = 12/306 (3%)
Query: 45 DYIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNH 104
+Y + +G G F VVR+ + +G + Q L E I + L H
Sbjct: 13 EYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQ--KLEREARICRLLKH 70
Query: 105 PNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQR 164
NIVR D + Y+V L TGGELF+ I+ + + E DA ++QIL+ V + HQ
Sbjct: 71 SNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQM 130
Query: 165 NIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSG 224
+VHRDLKPEN+L +K + + + DFG+A E++ D + AG+ GY++PEVL
Sbjct: 131 GVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEA 190
Query: 225 HGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKEF 284
+GKP DIW+ GVI Y LL GY PF E ++ +G Y F P W+ V+ AK
Sbjct: 191 YGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYD--FPSPEWDTVTPEAKNL 248
Query: 285 ILWALTVSPKRRPTATDLINDIWITSTEKSTTDLL------PEIRKGFDARKEFRDAVEI 338
I LT++P +R TA + + W+ ++ST + E K F+AR++ + A+
Sbjct: 249 INQMLTINPAKRITAHEALKHPWV--CQRSTVASMMHRQETVECLKKFNARRKLKGAILT 306
Query: 339 VKLNNR 344
L R
Sbjct: 307 TMLATR 312
>Hs4557511 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 454
Score = 176 bits (447), Expect = 5e-44
Identities = 101/271 (37%), Positives = 151/271 (55%), Gaps = 6/271 (2%)
Query: 46 YIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXG--QSVQLQMLYDELSILQQLN 103
Y G+ LG+G F +VR+ R +G+ + V + + E++IL+++
Sbjct: 13 YEMGEELGSGQFAIVRKCRQKGTGKEYAAKFIKKRRLSSSRRGVSREEIEREVNILREIR 72
Query: 104 HPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQ 163
HPNI+ D FE+K ++ +L +GGELFD + EK E +A +KQIL GV YLH
Sbjct: 73 HPNIITLHDIFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGVHYLHS 132
Query: 164 RNIVHRDLKPENILYLNKSDDSPLV-IGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTS 222
+ I H DLKPENI+ L+K+ +P + + DFGIA +++ NE G+ +VAPE++
Sbjct: 133 KRIAHFDLKPENIMLLDKNVPNPRIKLIDFGIAHKIEAGNE-FKNIFGTPEFVAPEIVNY 191
Query: 223 SGHGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAK 282
G D+WSIGVITY LL G SPFL E+ + ++ Y F + Y++N S+ AK
Sbjct: 192 EPLGLEADMWSIGVITYILLSGASPFLGETKQETLTNISAVNYD--FDEEYFSNTSELAK 249
Query: 283 EFILWALTVSPKRRPTATDLINDIWITSTEK 313
+FI L PKRR T + WI + +
Sbjct: 250 DFIRRLLVKDPKRRMTIAQSLEHSWIKAIRR 280
>Hs14776113 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 424
Score = 176 bits (445), Expect = 8e-44
Identities = 92/223 (41%), Positives = 134/223 (59%), Gaps = 3/223 (1%)
Query: 95 ELSILQQLNHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQI 154
EL +L+++ H NI++ + FE++E+ Y+V +LATGGELFDRI+ KG F E DA +++ +
Sbjct: 143 ELRVLRRVRHANIIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTERDATRVLQMV 202
Query: 155 LQGVQYLHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAK-ELKDDNELIHKAAGSMG 213
L GV+YLH I HRDLKPEN+LY + DS ++I DFG+A K D+ L+ G+
Sbjct: 203 LDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASARKKGDDCLMKTTCGTPE 262
Query: 214 YVAPEVLTSSGHGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPY 273
Y+APEVL + D+W++GVI Y LL G PF ++ + G+Y +
Sbjct: 263 YIAPEVLVRKPYTNSVDMWALGVIAYILLSGTMPFEDDNRTRLYRQILRGKYS--YSGEP 320
Query: 274 WNNVSKTAKEFILWALTVSPKRRPTATDLINDIWITSTEKSTT 316
W +VS AK+FI LTV P R TA + W+ S S++
Sbjct: 321 WPSVSNLAKDFIDRLLTVDPGARMTALQALRHPWVVSMAASSS 363
>At2g31500 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 582
Score = 175 bits (443), Expect = 1e-43
Identities = 124/390 (31%), Positives = 191/390 (48%), Gaps = 33/390 (8%)
Query: 2 FKKEPLSENNSRKPEEPEPVEGHKLTKLFNKVTGQPSSYVNKSD--------YIFGKTLG 53
F K P+ +S T L ++ QP S V Y GK LG
Sbjct: 14 FGKRPVRRRHSSNSRTSSVPRFDSSTNLSRRLIFQPPSRVLPEPIGDGIHLKYDLGKELG 73
Query: 54 AGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQL-NHPNIVRFKD 112
G FGV + IS+ E + + ++ + E+ I++ L HPNIV FK+
Sbjct: 74 RGEFGVTHECIEISTRERFACKRISKEKLRTE-IDVEDVRREVEIMRCLPKHPNIVSFKE 132
Query: 113 WFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRNIVHRDLK 172
FE K+ Y+V ++ GGELFDRI+ +G + E A + K IL+ V+ H+ ++HRDLK
Sbjct: 133 AFEDKDAVYLVMEICEGGELFDRIVSRGHYTERAAASVAKTILEVVKVCHEHGVIHRDLK 192
Query: 173 PENILYLNKSDDSPLVIGDFGIA---KELKDDNELIHKAAGSMGYVAPEVLTSSGHGKPC 229
PEN L+ N ++ + L DFG++ K + NE++ GS Y+APEVL + +G
Sbjct: 193 PENFLFSNGTETAQLKAIDFGLSIFFKPAQRFNEIV----GSPYYMAPEVLRRN-YGPEI 247
Query: 230 DIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKEFILWAL 289
D+WS GVI Y LLCG PF AE+ +G G + F + W VS AKE + L
Sbjct: 248 DVWSAGVILYILLCGVPPFWAETEEGIAHAIVRGN--IDFERDPWPKVSHEAKELVKNML 305
Query: 290 TVSPKRRPTATDLINDIWITSTEKSTTDLLPEIRKGFDARKEFRDAVEIVKLNNRIKK-- 347
+P R T +++ WI + E++ P + G + R + + + L NR KK
Sbjct: 306 DANPYSRLTVQEVLEHPWIRNAERA-----PNVNLGDNVRTKIQQFL----LMNRFKKKV 356
Query: 348 LKVLYEN--QDESDTDIEVNSTDSFSKNDY 375
L+++ +N +E +++ T KN +
Sbjct: 357 LRIVADNLPNEEIAAIVQMFQTMDTDKNGH 386
>At5g19360 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 523
Score = 174 bits (441), Expect = 2e-43
Identities = 116/318 (36%), Positives = 157/318 (48%), Gaps = 18/318 (5%)
Query: 3 KKEPLSENN---------SRKPEEPEPVEGHKLTKL--FNKVTGQPSSYVNKSDYIFGKT 51
K+EP EN S + + P TK V G+P V KS Y GK
Sbjct: 15 KEEPRPENGGGGVGAAEASVRASKHPPASPPPATKQGPIGPVLGRPMEDV-KSSYTLGKE 73
Query: 52 LGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLN-HPNIVRF 110
LG G FGV ++G + ++ + E+ I+ L PNIV
Sbjct: 74 LGRGQFGVTHLCTQKATGLQFACKTIAKRKLVNKE-DIEDVRREVQIMHHLTGQPNIVEL 132
Query: 111 KDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRNIVHRD 170
K +E K ++V +L GGELFDRI+ KG + E A +++ I+Q + H ++HRD
Sbjct: 133 KGAYEDKHSVHLVMELCAGGELFDRIIAKGHYSERAAASLLRTIVQIIHTCHSMGVIHRD 192
Query: 171 LKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSGHGKPCD 230
LKPEN L L+K ++SPL DFG++ K E+ GS Y+APEVL +G D
Sbjct: 193 LKPENFLLLSKDENSPLKATDFGLSVFYK-PGEVFKDIVGSAYYIAPEVLRRK-YGPEAD 250
Query: 231 IWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKEFILWALT 290
IWSIGV+ Y LLCG PF AES +G SGQ V F W +S AK+ + L
Sbjct: 251 IWSIGVMLYILLCGVPPFWAESENGIFNAILSGQ--VDFSSDPWPVISPQAKDLVRKMLN 308
Query: 291 VSPKRRPTATDLINDIWI 308
PK+R TA ++N WI
Sbjct: 309 SDPKQRLTAAQVLNHPWI 326
>At5g12180 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 528
Score = 173 bits (439), Expect = 4e-43
Identities = 106/277 (38%), Positives = 144/277 (51%), Gaps = 7/277 (2%)
Query: 33 VTGQPSSYVNKSDYIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQML 92
V G+P V K+ Y GK LG G FGV ++G + ++ +
Sbjct: 61 VLGRPMEDV-KASYSLGKELGRGQFGVTHLCTQKATGHQFACKTIAKRKLVNKE-DIEDV 118
Query: 93 YDELSILQQLN-HPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIV 151
E+ I+ L PNIV K +E K ++V +L GGELFDRI+ KG + E A ++
Sbjct: 119 RREVQIMHHLTGQPNIVELKGAYEDKHSVHLVMELCAGGELFDRIIAKGHYSERAAASLL 178
Query: 152 KQILQGVQYLHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGS 211
+ I+Q V H ++HRDLKPEN L LNK ++SPL DFG++ K E+ GS
Sbjct: 179 RTIVQIVHTCHSMGVIHRDLKPENFLLLNKDENSPLKATDFGLSVFYK-PGEVFKDIVGS 237
Query: 212 MGYVAPEVLTSSGHGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHK 271
Y+APEVL +G DIWSIGV+ Y LLCG PF AES +G G V F
Sbjct: 238 AYYIAPEVLKRK-YGPEADIWSIGVMLYILLCGVPPFWAESENGIFNAILRGH--VDFSS 294
Query: 272 PYWNNVSKTAKEFILWALTVSPKRRPTATDLINDIWI 308
W ++S AK+ + L PK+R TA ++N WI
Sbjct: 295 DPWPSISPQAKDLVKKMLNSDPKQRLTAAQVLNHPWI 331
>Hs13129008 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 501
Score = 172 bits (437), Expect = 7e-43
Identities = 97/265 (36%), Positives = 159/265 (59%), Gaps = 18/265 (6%)
Query: 94 DELSILQQLNHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQ 153
+E+ IL+ + HPNI++ D F ++++++I +LATG E+FD IL++G + E D +V+Q
Sbjct: 69 NEIGILKMVKHPNILQLVDVFVTRKEYFIFLELATGREVFDWILDQGYYSERDTSNVVRQ 128
Query: 154 ILQGVQYLHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMG 213
+L+ V YLH IVHR+LK EN++Y N+ +S +VI DF +AK +N LI + G+
Sbjct: 129 VLEAVAYLHSLKIVHRNLKLENLVYYNRLKNSKIVISDFHLAKL---ENGLIKEPCGTPE 185
Query: 214 YVAPEVLTSSGHGKPCDIWSIGVITYTLLCGYSPFLAESAD--------GFIEECTSGQY 265
Y+APEV+ +G+P D W+IGVI Y LL G PF E + + +G Y
Sbjct: 186 YLAPEVVGRQRYGRPVDCWAIGVIMYILLSGNPPFYEEVEEDDYENHDKNLFRKILAGDY 245
Query: 266 PVVFHKPYWNNVSKTAKEFILWALTVSPKRRPTATDLINDIWIT---STEKSTTD-LLPE 321
F PYW+++S+ AK+ + + V +R TA + I+ WI+ +++K+ D + +
Sbjct: 246 E--FDSPYWDDISQAAKDLVTRLMEVEQDQRITAEEAISHEWISGNAASDKNIKDGVCAQ 303
Query: 322 IRKGFDARKEFRDAVEIVKLNNRIK 346
I K F AR +++ AV + L R++
Sbjct: 304 IEKNF-ARAKWKKAVRVTTLMKRLR 327
>At4g04720 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 531
Score = 172 bits (437), Expect = 7e-43
Identities = 121/369 (32%), Positives = 181/369 (48%), Gaps = 34/369 (9%)
Query: 13 RKPEEP------EPVEGHKLTKLFNKVT--------GQPSSYVNKSDYIFGKTLGAGTFG 58
RKP+ P +P+ T N V+ G+P + K Y GK LG G FG
Sbjct: 34 RKPQTPTPKPMTQPIHQQISTPSSNPVSVRDPDTILGKPFEDIRKF-YSLGKELGRGQFG 92
Query: 59 VVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLN-HPNIVRFKDWFESK 117
+ + I +G + + + + E+ I+Q L+ PNIV K +E +
Sbjct: 93 ITYMCKEIGTGNTYACKSILKRKLISKQDK-EDVKREIQIMQYLSGQPNIVEIKGAYEDR 151
Query: 118 EKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRNIVHRDLKPENIL 177
+ ++V +L GGELFDRI+ +G + E A I++ I+ VQ H +VHRDLKPEN L
Sbjct: 152 QSIHLVMELCAGGELFDRIIAQGHYSERAAAGIIRSIVNVVQICHFMGVVHRDLKPENFL 211
Query: 178 YLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSGHGKPCDIWSIGVI 237
+K +++ L DFG++ + ++ ++ GS YVAPEVL S +GK DIWS GVI
Sbjct: 212 LSSKEENAMLKATDFGLSVFI-EEGKVYRDIVGSAYYVAPEVLRRS-YGKEIDIWSAGVI 269
Query: 238 TYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKEFILWALTVSPKRRP 297
Y LL G PF AE+ G +E G+ + F W ++S++AK+ + LT PKRR
Sbjct: 270 LYILLSGVPPFWAENEKGIFDEVIKGE--IDFVSEPWPSISESAKDLVRKMLTKDPKRRI 327
Query: 298 TATDLINDIWITSTEKSTTDLLPEIRKGFDARKEFRDAVEIVKL----------NNRIKK 347
TA ++ WI E + + K+FR ++ KL IK
Sbjct: 328 TAAQVLEHPWIKGGEAPDKPIDSAV---LSRMKQFRAMNKLKKLALKVIAESLSEEEIKG 384
Query: 348 LKVLYENQD 356
LK ++ N D
Sbjct: 385 LKTMFANID 393
>At2g41860 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 530
Score = 172 bits (436), Expect = 9e-43
Identities = 112/331 (33%), Positives = 173/331 (51%), Gaps = 17/331 (5%)
Query: 33 VTGQPSSYVNKSDYIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQML 92
V +P+ + K Y G+ LG G FGV I +GE S+ ++ +
Sbjct: 41 VLKEPTGHEIKQKYKLGRELGRGEFGVTYLCTEIETGE-IFACKSILKKKLKTSIDIEDV 99
Query: 93 YDELSILQQL-NHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIV 151
E+ I++Q+ HPNIV K+ +E + ++V +L GGELFDRI+ +G + E A ++
Sbjct: 100 KREVEIMRQMPEHPNIVTLKETYEDDKAVHLVMELCEGGELFDRIVARGHYTERAAASVI 159
Query: 152 KQILQGVQYLHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGS 211
K I++ VQ H+ ++HRDLKPEN L+ NK + + L DFG++ K E ++ GS
Sbjct: 160 KTIIEVVQMCHKHGVMHRDLKPENFLFANKKETASLKAIDFGLSVFFK-PGERFNEIVGS 218
Query: 212 MGYVAPEVLTSSGHGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHK 271
Y+APEVL S +G+ DIWS GVI Y LLCG PF AE+ G + + F +
Sbjct: 219 PYYMAPEVLRRS-YGQEIDIWSAGVILYILLCGVPPFWAETEHGVAKAILKS--VIDFKR 275
Query: 272 PYWNNVSKTAKEFILWALTVSPKRRPTATDLINDIWITSTEKSTTDLLPEIRKGFDARKE 331
W VS AK+ I L P+RR TA +++ WI + + ++ L E
Sbjct: 276 DPWPKVSDNAKDLIKKMLHPDPRRRLTAQQVLDHPWIQNGKNASNVSLGE---------T 326
Query: 332 FRDAVEIVKLNNRIKK--LKVLYENQDESDT 360
R ++ + N++KK L+V+ E+ +T
Sbjct: 327 VRARLKQFSVMNKLKKRALRVIAEHLSVEET 357
>Hs20149547 [T] KOG0603 Ribosomal protein S6 kinase
Length = 735
Score = 172 bits (435), Expect = 1e-42
Identities = 102/305 (33%), Positives = 165/305 (53%), Gaps = 21/305 (6%)
Query: 14 KPEEPEPVEGHKLTKLFNKVTGQPSSYVNKSDYIFGKTLGAGTFGVVRQARCISSGENXX 73
KP P+ + +L K + V Y+ +T+G G++ + RC+ N
Sbjct: 392 KPRAPQAPLHSVVQQLHGK------NLVFSDGYVVKETIGVGSYSECK--RCVHKATNME 443
Query: 74 XXXXXXXXXXGQ-SVQLQMLYDELSILQQLNHPNIVRFKDWFESKEKFYIVTQLATGGEL 132
S ++++L L+ HPNI+ KD ++ + Y+VT+L GGEL
Sbjct: 444 YAVKVIDKSKRDPSEEIEIL------LRYGQHPNIITLKDVYDDGKHVYLVTELMRGGEL 497
Query: 133 FDRILEKGKFCEVDAVFIVKQILQGVQYLHQRNIVHRDLKPENILYLNKSDDSP-LVIGD 191
D+IL + F E +A F++ I + V+YLH + +VHRDLKP NILY+++S + L I D
Sbjct: 498 LDKILRQKFFSEREASFVLHTIGKTVEYLHSQGVVHRDLKPSNILYVDESGNPECLRICD 557
Query: 192 FGIAKELKDDNELIHKAAGSMGYVAPEVLTSSGHGKPCDIWSIGVITYTLLCGYSPFL-- 249
FG AK+L+ +N L+ + +VAPEVL G+ + CDIWS+G++ YT+L GY+PF
Sbjct: 558 FGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDEGCDIWSLGILLYTMLAGYTPFANG 617
Query: 250 -AESADGFIEECTSGQYPVVFHKPYWNNVSKTAKEFILWALTVSPKRRPTATDLINDIWI 308
+++ + + SG++ WN VS+TAK+ + L V P +R TA ++ W+
Sbjct: 618 PSDTPEEILTRIGSGKF--TLSGGNWNTVSETAKDLVSKMLHVDPHQRLTAKQVLQHPWV 675
Query: 309 TSTEK 313
T +K
Sbjct: 676 TQKDK 680
Score = 117 bits (293), Expect = 3e-26
Identities = 66/212 (31%), Positives = 110/212 (51%), Gaps = 4/212 (1%)
Query: 38 SSYVNKSDYIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYD-EL 96
S + S + K LG G+FG V R ++ ++ V+ ++ E
Sbjct: 54 SEKADPSHFELLKVLGQGSFGKVFLVRKVTRPDSGHLYAMKVLKKATLKVRDRVRTKMER 113
Query: 97 SILQQLNHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQ 156
IL +NHP +V+ F+++ K Y++ GG+LF R+ ++ F E D F + ++
Sbjct: 114 DILADVNHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELAL 173
Query: 157 GVQYLHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVA 216
G+ +LH I++RDLKPENIL ++ + + DFG++KE D + + G++ Y+A
Sbjct: 174 GLDHLHSLGIIYRDLKPENILL---DEEGHIKLTDFGLSKEAIDHEKKAYSFCGTVEYMA 230
Query: 217 PEVLTSSGHGKPCDIWSIGVITYTLLCGYSPF 248
PEV+ GH D WS GV+ + +L G PF
Sbjct: 231 PEVVNRQGHSHSADWWSYGVLMFEMLTGSLPF 262
>At4g04740 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 520
Score = 172 bits (435), Expect = 1e-42
Identities = 117/352 (33%), Positives = 178/352 (50%), Gaps = 15/352 (4%)
Query: 13 RKPEEPEPVEGHKLTKLFNKVTGQPSSYVNKSDYIFGKTLGAGTFGVVRQARCISSGENX 72
RKP+ P P + + G+P + K Y G+ LG G G+ + I +G N
Sbjct: 38 RKPQIPSPSIPISVRDP-ETILGKPFEDIRKF-YSLGRELGRGGLGITYMCKEIGTG-NI 94
Query: 73 XXXXXXXXXXXGQSVQLQMLYDELSILQQLN-HPNIVRFKDWFESKEKFYIVTQLATGGE 131
+ + + E+ I+Q L+ PN+V K +E + ++V +L GGE
Sbjct: 95 YACKSILKRKLISELGREDVKTEIQIMQHLSGQPNVVEIKGSYEDRHSVHLVMELCAGGE 154
Query: 132 LFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRNIVHRDLKPENILYLNKSDDSPLVIGD 191
LFDRI+ +G + E A +K I+ VQ H ++HRDLKPEN L+ +K +++ L + D
Sbjct: 155 LFDRIIAQGHYSERAAAGTIKSIVDVVQICHLNGVIHRDLKPENFLFSSKEENAMLKVTD 214
Query: 192 FGIAKELKDDNELIHKAAGSMGYVAPEVLTSSGHGKPCDIWSIGVITYTLLCGYSPFLAE 251
FG++ + ++ ++ GS YVAPEVL S +GK DIWS GVI Y LLCG PF A+
Sbjct: 215 FGLSAFI-EEGKIYKDVVGSPYYVAPEVLRQS-YGKEIDIWSAGVILYILLCGVPPFWAD 272
Query: 252 SADGFIEECTSGQYPVVFHKPYWNNVSKTAKEFILWALTVSPKRRPTATDLINDIWI--- 308
+ +G E + + F + W ++S +AK+ + LT PKRR TA ++ WI
Sbjct: 273 NEEGVFVEIL--KCKIDFVREPWPSISDSAKDLVEKMLTEDPKRRITAAQVLEHPWIKGG 330
Query: 309 TSTEKSTTDLLPEIRKGFDARKEFRD---AVEIVKLN-NRIKKLKVLYENQD 356
+ EK + K F A + + V V L+ IK LK L+ N D
Sbjct: 331 EAPEKPIDSTVLSRMKQFRAMNKLKKLALKVSAVSLSEEEIKGLKTLFANMD 382
>At5g19450 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 533
Score = 171 bits (432), Expect = 3e-42
Identities = 108/310 (34%), Positives = 163/310 (51%), Gaps = 13/310 (4%)
Query: 46 YIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQL-NH 104
Y G+ +G G FG+ I +GE +V ++ + E+ I++ + H
Sbjct: 57 YDLGREVGRGEFGITYLCTDIKTGEKYACKSISKKKLR-TAVDIEDVRREVEIMKHMPRH 115
Query: 105 PNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQR 164
PNIV KD FE + +IV +L GGELFDRI+ +G + E A ++K IL+ VQ H+
Sbjct: 116 PNIVSLKDAFEDDDAVHIVMELCEGGELFDRIVARGHYTERAAAAVMKTILEVVQICHKH 175
Query: 165 NIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSG 224
++HRDLKPEN L+ NK + S L DFG++ K E ++ GS Y+APEVL +
Sbjct: 176 GVMHRDLKPENFLFANKKETSALKAIDFGLSVFFK-PGEGFNEIVGSPYYMAPEVLRRN- 233
Query: 225 HGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKEF 284
+G DIWS GVI Y LLCG PF AE+ G + + + F + W VS+TAK+
Sbjct: 234 YGPEVDIWSAGVILYILLCGVPPFWAETEQGVAQAII--RSVIDFKRDPWPRVSETAKDL 291
Query: 285 ILWALTVSPKRRPTATDLINDIWITSTEKSTTDLLPEIRKGFDARKEFRDAVEIVKLNNR 344
+ L PK+R +A ++ WI + +K+ P + G + + + KL R
Sbjct: 292 VRKMLEPDPKKRLSAAQVLEHSWIQNAKKA-----PNVSLGETVKARLKQFSVMNKLKKR 346
Query: 345 IKKLKVLYEN 354
L+V+ E+
Sbjct: 347 --ALRVIAEH 354
>Hs4758128_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 385
Score = 171 bits (432), Expect = 3e-42
Identities = 101/279 (36%), Positives = 148/279 (52%), Gaps = 17/279 (6%)
Query: 46 YIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNHP 105
Y G+T+G G F VV++ S+ G+ M+ +E+SIL+++ HP
Sbjct: 46 YKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCRGKE---HMIQNEVSILRRVKHP 102
Query: 106 NIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRN 165
NIV + + + Y+V +L GG+LFD I K+ E DA ++ + ++YLH N
Sbjct: 103 NIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLN 162
Query: 166 IVHRDLKPENILYLNKSDDS-PLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSG 224
IVHRD+KPEN+L D S L +GDFG+A + ++ G+ YVAPE++ +G
Sbjct: 163 IVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIVDGP---LYTVCGTPTYVAPEIIAETG 219
Query: 225 HGKPCDIWSIGVITYTLLCGYSPFLAESADG--FIEECTSGQYPVVFHKPYWNNVSKTAK 282
+G DIW+ GVITY LLCG+ PF D ++ GQ V F PYW+NVS +AK
Sbjct: 220 YGLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQ--VDFPSPYWDNVSDSAK 277
Query: 283 EFILWALTVSPKRRPTATDLINDIWITSTEKSTTDLLPE 321
E I L V +R +A ++ W+ D LPE
Sbjct: 278 ELITMMLLVDVDQRFSAVQVLEHPWVND------DGLPE 310
>At3g51850 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 503
Score = 168 bits (426), Expect = 1e-41
Identities = 116/369 (31%), Positives = 179/369 (48%), Gaps = 17/369 (4%)
Query: 4 KEPLSENNSRKPEEPEPVEGHKLTKLFNKVTGQPSSYVNKSDYIFGKTLGAGTFGVVRQA 63
+E + N S + G K + ++ P + + Y+ + LG G FGV
Sbjct: 13 REDVKSNYSGHDHARKDAAGGKKSAPIRVLSDVPKENI-EDRYLLDRELGRGEFGVTYL- 70
Query: 64 RCIS-SGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQL-NHPNIVRFKDWFESKEKFY 121
CI S + +V ++ + E++I++ L +IV K+ E +
Sbjct: 71 -CIERSSRDLLACKSISKRKLRTAVDIEDVKREVAIMKHLPKSSSIVTLKEACEDDNAVH 129
Query: 122 IVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRNIVHRDLKPENILYLNK 181
+V +L GGELFDRI+ +G + E A + K I++ VQ H+ ++HRDLKPEN L+ NK
Sbjct: 130 LVMELCEGGELFDRIVARGHYTERAAAGVTKTIVEVVQLCHKHGVIHRDLKPENFLFANK 189
Query: 182 SDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSGHGKPCDIWSIGVITYTL 241
++SPL DFG++ K E + GS Y+APEVL +G DIWS GVI Y L
Sbjct: 190 KENSPLKAIDFGLSIFFK-PGEKFSEIVGSPYYMAPEVL-KRNYGPEIDIWSAGVILYIL 247
Query: 242 LCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKEFILWALTVSPKRRPTATD 301
LCG PF AES G + G + F + W N+S+TAK + L PKRR TA
Sbjct: 248 LCGVPPFWAESEQGVAQAILRG--VIDFKREPWPNISETAKNLVRQMLEPDPKRRLTAKQ 305
Query: 302 LINDIWITSTEKSTT----DLLPEIRKGFDARKEF-RDAVEIVK---LNNRIKKLKVLYE 353
++ WI + +K+ D++ K F F R A+ ++ ++ +KV++
Sbjct: 306 VLEHPWIQNAKKAPNVPLGDVVKSRLKQFSVMNRFKRKALRVIAEFLSTEEVEDIKVMFN 365
Query: 354 NQDESDTDI 362
D + I
Sbjct: 366 KMDTDNDGI 374
>At1g76040 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 534
Score = 167 bits (423), Expect = 3e-41
Identities = 112/354 (31%), Positives = 177/354 (49%), Gaps = 18/354 (5%)
Query: 15 PEEPEPVEGHKLTKLFNKVTGQPSSYVNKSDYIFGKTLGAGTFGVVRQARCISSGENXXX 74
P P G ++ + N+ S+ Y K LG G FG+ + S+G
Sbjct: 59 PPPPSTSSGSQIGPILNRPMIDLSAL-----YDLHKELGRGQFGITYKCTDKSNGREYAC 113
Query: 75 XXXXXXXXXGQSVQLQMLYDELSILQQLN-HPNIVRFKDWFESKEKFYIVTQLATGGELF 133
+ ++ + E+ ILQ L PNIV F+ +E K+ ++V +L +GGELF
Sbjct: 114 KSISKRKLIRRK-DIEDVRREVMILQHLTGQPNIVEFRGAYEDKDNLHLVMELCSGGELF 172
Query: 134 DRILEKGKFCEVDAVFIVKQILQGVQYLHQRNIVHRDLKPENILYLNKSDDSPLVIGDFG 193
DRI++KG + E +A I +QI+ V H +VHRDLKPEN L ++ +DSP+ DFG
Sbjct: 173 DRIIKKGSYSEKEAANIFRQIVNVVHVCHFMGVVHRDLKPENFLLVSNEEDSPIKATDFG 232
Query: 194 IAKELKDDNELIHKAAGSMGYVAPEVLTSSGHGKPCDIWSIGVITYTLLCGYSPFLAESA 253
++ + ++ ++ GS YVAPEVL +GK D+WS GV+ Y LL G PF E+
Sbjct: 233 LSVFI-EEGKVYRDIVGSAYYVAPEVL-HRNYGKEIDVWSAGVMLYILLSGVPPFWGETE 290
Query: 254 DGFIEECTSGQYPVVFHKPYWNNVSKTAKEFILWALTVSPKRRPTATDLINDIWITSTEK 313
E G+ + W +S++AK+ I L PK+R TA + + W+T T+
Sbjct: 291 KTIFEAILEGKLDL--ETSPWPTISESAKDLIRKMLIRDPKKRITAAEALEHPWMTDTKI 348
Query: 314 STTDLLPEI---RKGFDARKEFRD-AVEIVKLN---NRIKKLKVLYENQDESDT 360
S + + K F A + + A++++ N IK LK ++N D ++
Sbjct: 349 SDKPINSAVLVRMKQFRAMNKLKKLALKVIAENLSEEEIKGLKQTFKNMDTDES 402
>At2g17890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 571
Score = 166 bits (421), Expect = 5e-41
Identities = 102/266 (38%), Positives = 142/266 (53%), Gaps = 8/266 (3%)
Query: 46 YIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLN-H 104
Y GK LG G FG A +G+ + ++ + E+ ILQ L H
Sbjct: 108 YTIGKLLGHGQFGYTYVATDKKTGDRVAVKKIDKAKMT-IPIAVEDVKREVKILQALTGH 166
Query: 105 PNIVRFKDWFESKEKFYIVTQLATGGELFDRILEK--GKFCEVDAVFIVKQILQGVQYLH 162
N+VRF + FE K YIV +L GGEL DRIL + ++ E DA +V+Q+L+ H
Sbjct: 167 ENVVRFYNAFEDKNSVYIVMELCEGGELLDRILARKDSRYSERDAAVVVRQMLKVAAECH 226
Query: 163 QRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTS 222
R +VHRD+KPEN L+ + +DSPL DFG++ +K + H GS YVAPEVL
Sbjct: 227 LRGLVHRDMKPENFLFKSTEEDSPLKATDFGLSDFIKPGKK-FHDIVGSAYYVAPEVLKR 285
Query: 223 SGHGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAK 282
G D+WSIGVI+Y LLCG PF ++ DG +E + P KP W +S +AK
Sbjct: 286 RS-GPESDVWSIGVISYILLCGRRPFWDKTEDGIFKEVLKNK-PDFRRKP-WPTISNSAK 342
Query: 283 EFILWALTVSPKRRPTATDLINDIWI 308
+F+ L P+ R TA ++ W+
Sbjct: 343 DFVKKLLVKDPRARLTAAQALSHPWV 368
>At1g61950 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 547
Score = 166 bits (420), Expect = 6e-41
Identities = 112/356 (31%), Positives = 182/356 (50%), Gaps = 19/356 (5%)
Query: 14 KPEEPEPVEGHKLTKLFNK---VTGQPSSYVNKSDYIFGKTLGAGTFGVVRQARCISSGE 70
+P+E + + H+ + + G+P + K Y G+ LG G FG+ ISSG+
Sbjct: 64 QPQEKQKLINHQKQSTLQQPEPILGRPFEDI-KEKYSLGRELGRGQFGITYICTEISSGK 122
Query: 71 NXXXXXXXXXXXXGQSVQLQMLYDELSILQQLN-HPNIVRFKDWFESKEKFYIVTQLATG 129
N ++ + + E+ I+ L+ PNIV K +E ++ ++V +L G
Sbjct: 123 NFACKSILKRKLI-RTKDREDVRREIQIMHYLSGQPNIVEIKGAYEDRQSVHLVMELCEG 181
Query: 130 GELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRNIVHRDLKPENILYLNKSD-DSPLV 188
GELFD+I ++G + E A I++ +++ VQ H ++HRDLKPEN L +K + S L
Sbjct: 182 GELFDKITKRGHYSEKAAAEIIRSVVKVVQICHFMGVIHRDLKPENFLLSSKDEASSMLK 241
Query: 189 IGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSGHGKPCDIWSIGVITYTLLCGYSPF 248
DFG++ + ++ ++ GS YVAPEVL +GK DIWS GVI Y LLCG PF
Sbjct: 242 ATDFGVSVFI-EEGKVYEDIVGSAYYVAPEVL-KRNYGKAIDIWSAGVILYILLCGNPPF 299
Query: 249 LAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKEFILWALTVSPKRRPTATDLINDIWI 308
AE+ G EE G+ + F W ++S++AK+ + L PK+R TA ++ WI
Sbjct: 300 WAETDKGIFEEILRGE--IDFESEPWPSISESAKDLVRNMLKYDPKKRFTAAQVLEHPWI 357
Query: 309 -----TSTEKSTTDLLPEIRKGFDARKEFRDAVEIVKLN---NRIKKLKVLYENQD 356
S + + +L +++ K + A + + N +K LK ++ N D
Sbjct: 358 REGGEASDKPIDSAVLSRMKQLRAMNKLKKLAFKFIAQNLKEEELKGLKTMFANMD 413
>Hs14670383 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 370
Score = 166 bits (419), Expect = 8e-41
Identities = 106/339 (31%), Positives = 178/339 (52%), Gaps = 16/339 (4%)
Query: 46 YIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXG--QSVQLQMLYDELSILQQLN 103
Y G+ LG+G F +V++ R S+G + V + + E+SIL+Q+
Sbjct: 23 YDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGVSREEIEREVSILRQVL 82
Query: 104 HPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQ 163
H N++ D +E++ ++ +L +GGELFD + +K E +A +KQIL GV YLH
Sbjct: 83 HHNVITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEATSFIKQILDGVNYLHT 142
Query: 164 RNIVHRDLKPENILYLNKSDDSP-LVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTS 222
+ I H DLKPENI+ L+K+ P + + DFG+A E++D E G+ +VAPE++
Sbjct: 143 KKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIEDGVE-FKNIFGTPEFVAPEIVNY 201
Query: 223 SGHGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAK 282
G D+WSIGVITY LL G SPFL ++ + T+ Y F + +++ S+ AK
Sbjct: 202 EPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANITAVSYD--FDEEFFSQTSELAK 259
Query: 283 EFILWALTVSPKRRPTATDLINDIWITSTE-------KSTTDLLPEIRKGFDARKEFRDA 335
+FI L ++R T + + WIT + + + L RK + R+ ++ +
Sbjct: 260 DFIRKLLVKETRKRLTIQEALRHPWITPVDNQQAMVRRESVVNLENFRKQY-VRRRWKLS 318
Query: 336 VEIVKLNNRIKK--LKVLYENQDESDTDIEVNSTDSFSK 372
IV L N + + +K ++ DE + E ++ + ++
Sbjct: 319 FSIVSLCNHLTRSLMKKVHLRPDEDLRNCESDTEEDIAR 357
>At4g21940 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 554
Score = 166 bits (419), Expect = 8e-41
Identities = 113/373 (30%), Positives = 180/373 (47%), Gaps = 33/373 (8%)
Query: 8 SENNSRKPEEPEPV-----EGHKLTKLFNKVT--------GQPSSYVNKSDYIFGKTLGA 54
+++N +E +PV + H LT+ + G+P + K Y GK LG
Sbjct: 52 TQSNHHHQQESKPVNQQIEKKHVLTQPLKPIVFRETETILGKPFEEIRKL-YTLGKELGR 110
Query: 55 GTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLN-HPNIVRFKDW 113
G FG+ + S+G N + + + E+ I+Q L+ NIV K
Sbjct: 111 GQFGITYTCKENSTG-NTYACKSILKRKLTRKQDIDDVKREIQIMQYLSGQENIVEIKGA 169
Query: 114 FESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRNIVHRDLKP 173
+E ++ ++V +L G ELFDRI+ +G + E A +++ +L VQ H ++HRDLKP
Sbjct: 170 YEDRQSIHLVMELCGGSELFDRIIAQGHYSEKAAAGVIRSVLNVVQICHFMGVIHRDLKP 229
Query: 174 ENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSGHGKPCDIWS 233
EN L + +++ L DFG++ + ++ ++ GS YVAPEVL S +GK DIWS
Sbjct: 230 ENFLLASTDENAMLKATDFGLSVFI-EEGKVYRDIVGSAYYVAPEVLRRS-YGKEIDIWS 287
Query: 234 IGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKEFILWALTVSP 293
G+I Y LLCG PF +E+ G E G+ + F W ++S++AK+ + LT P
Sbjct: 288 AGIILYILLCGVPPFWSETEKGIFNEIIKGE--IDFDSQPWPSISESAKDLVRKLLTKDP 345
Query: 294 KRRPTATDLINDIWITSTEKSTTDLLPEIRKGFDARKEFRDAVEIVKL----------NN 343
K+R +A + WI E + + K+FR ++ KL
Sbjct: 346 KQRISAAQALEHPWIRGGEAPDKPIDSAV---LSRMKQFRAMNKLKKLALKVIAESLSEE 402
Query: 344 RIKKLKVLYENQD 356
IK LK ++ N D
Sbjct: 403 EIKGLKTMFANMD 415
>Hs4759050 [T] KOG0603 Ribosomal protein S6 kinase
Length = 740
Score = 164 bits (415), Expect = 2e-40
Identities = 99/267 (37%), Positives = 145/267 (54%), Gaps = 13/267 (4%)
Query: 46 YIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLN-H 104
Y + +G G++ V + RCI N + E+ IL + H
Sbjct: 422 YEVKEDIGVGSYSVCK--RCIHKATNMEFAVKIIDKSKRDPTE------EIEILLRYGQH 473
Query: 105 PNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQR 164
PNI+ KD ++ + Y+VT+L GGEL D+IL + F E +A ++ I + V+YLH +
Sbjct: 474 PNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQ 533
Query: 165 NIVHRDLKPENILYLNKSDDSPLV-IGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSS 223
+VHRDLKP NILY+++S + + I DFG AK+L+ +N L+ + +VAPEVL
Sbjct: 534 GVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQ 593
Query: 224 GHGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTS--GQYPVVFHKPYWNNVSKTA 281
G+ CDIWS+GV+ YT+L GY+PF A D EE + G YWN+VS TA
Sbjct: 594 GYDAACDIWSLGVLLYTMLTGYTPF-ANGPDDTPEEILARIGSGKFSLSGGYWNSVSDTA 652
Query: 282 KEFILWALTVSPKRRPTATDLINDIWI 308
K+ + L V P +R TA ++ WI
Sbjct: 653 KDLVSKMLHVDPHQRLTAALVLRHPWI 679
Score = 115 bits (288), Expect = 1e-25
Identities = 65/200 (32%), Positives = 106/200 (52%), Gaps = 4/200 (2%)
Query: 50 KTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYD-ELSILQQLNHPNIV 108
K LG G+FG V + IS + V+ ++ E IL ++NHP IV
Sbjct: 72 KVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMERDILVEVNHPFIV 131
Query: 109 RFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRNIVH 168
+ F+++ K Y++ GG+LF R+ ++ F E D F + ++ + +LH I++
Sbjct: 132 KLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGIIY 191
Query: 169 RDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSGHGKP 228
RDLKPENIL ++ + + DFG++KE D + + G++ Y+APEV+ GH +
Sbjct: 192 RDLKPENILL---DEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVNRRGHTQS 248
Query: 229 CDIWSIGVITYTLLCGYSPF 248
D WS GV+ + +L G PF
Sbjct: 249 ADWWSFGVLMFEMLTGTLPF 268
>Hs22043888 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 765
Score = 163 bits (413), Expect = 4e-40
Identities = 92/295 (31%), Positives = 157/295 (53%), Gaps = 23/295 (7%)
Query: 46 YIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQ--------------- 90
Y GK +G G F VV++ S+G+ G+
Sbjct: 198 YKIGKVIGDGNFAVVKECIDRSTGKEFALKIIDKAKCCGKQCAPSNTDTSCEAIVGSTEH 257
Query: 91 MLYDELSILQQLNHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFI 150
++ +E+SIL+++ HPNI+ + E+ + ++V +L GG+LFD I K+ E D +
Sbjct: 258 LIENEVSILRRVKHPNIIMLVEEMETATELFLVMELVKGGDLFDAITSSTKYTERDGSAM 317
Query: 151 VKQILQGVQYLHQRNIVHRDLKPENILYLNKSDDS-PLVIGDFGIAKELKDDNELIHKAA 209
V + ++YLH +IVHRD+KPEN+L D + L +GDFG+A ++ ++
Sbjct: 318 VYNLANALRYLHGLSIVHRDIKPENLLVCEYPDGTKSLKLGDFGLATVVEGP---LYTVC 374
Query: 210 GSMGYVAPEVLTSSGHGKPCDIWSIGVITYTLLCGYSPFLAES--ADGFIEECTSGQYPV 267
G+ YVAPE++ +G+G DIW+ GVITY LLCG+ PF +E+ + ++ +G+ +
Sbjct: 375 GTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCGFPPFRSENNLQEDLFDQILAGK--L 432
Query: 268 VFHKPYWNNVSKTAKEFILWALTVSPKRRPTATDLINDIWITSTEKSTTDLLPEI 322
F PYW+N++ +AKE I L V+ + R TA +++ W++ ++ E+
Sbjct: 433 EFPAPYWDNITDSAKELISQMLQVNVEARCTAGQILSHPWVSDDASQENNMQAEV 487
>At3g57530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 560
Score = 163 bits (412), Expect = 5e-40
Identities = 105/328 (32%), Positives = 166/328 (50%), Gaps = 13/328 (3%)
Query: 33 VTGQPSSYVNKSDYIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQML 92
V P+ +S Y G+ LG G FGV + ++ +V ++ +
Sbjct: 50 VLNDPTGREIESKYTLGRELGRGEFGVTYLCTDKET-DDVFACKSILKKKLRTAVDIEDV 108
Query: 93 YDELSILQQL-NHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIV 151
E+ I++ + HPN+V K+ +E + ++V +L GGELFDRI+ +G + E A +
Sbjct: 109 RREVEIMRHMPEHPNVVTLKETYEDEHAVHLVMELCEGGELFDRIVARGHYTERAAAAVT 168
Query: 152 KQILQGVQYLHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGS 211
K I++ VQ H+ ++HRDLKPEN L+ NK + +PL DFG++ K E ++ GS
Sbjct: 169 KTIMEVVQVCHKHGVMHRDLKPENFLFGNKKETAPLKAIDFGLSVFFK-PGERFNEIVGS 227
Query: 212 MGYVAPEVLTSSGHGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHK 271
Y+APEVL +G DIWS GVI Y LLCG PF AE+ G + + + F +
Sbjct: 228 PYYMAPEVL-KRNYGPEVDIWSAGVILYILLCGVPPFWAETEQGVAQAII--RSVLDFRR 284
Query: 272 PYWNNVSKTAKEFILWALTVSPKRRPTATDLINDIWITSTEKSTTDLLPEIRKGFDARKE 331
W VS+ AK+ I L KRR TA +++ W+ + + + P + G R
Sbjct: 285 DPWPKVSENAKDLIRKMLDPDQKRRLTAQQVLDHPWLQNAKTA-----PNVSLGETVRAR 339
Query: 332 FRDAVEIVKLNNRIKKLKVLYENQDESD 359
+ + KL R L+V+ E+ + +
Sbjct: 340 LKQFTVMNKLKKR--ALRVIAEHLSDEE 365
>At3g20410 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 541
Score = 161 bits (408), Expect = 2e-39
Identities = 107/315 (33%), Positives = 161/315 (50%), Gaps = 13/315 (4%)
Query: 46 YIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLN-H 104
Y GK LG G FGV S+G+ ++ + M E+ I+Q L+
Sbjct: 91 YTLGKELGRGQFGVTYLCTENSTGKKYACKSISKKKLVTKADKDDMRR-EIQIMQHLSGQ 149
Query: 105 PNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQR 164
PNIV FK +E ++ +V +L GGELFDRI+ KG + E A + +QI+ V+ H
Sbjct: 150 PNIVEFKGAYEDEKAVNLVMELCAGGELFDRIIAKGHYTERAAASVCRQIVNVVKICHFM 209
Query: 165 NIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSG 224
++HRDLKPEN L +K + + + DFG++ + ++ ++ GS YVAPEVL
Sbjct: 210 GVLHRDLKPENFLLSSKDEKALIKATDFGLSVFI-EEGKVYRDIVGSAYYVAPEVLRRR- 267
Query: 225 HGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKEF 284
+GK DIWS G+I Y LL G PF AE+ G + G + F W ++S +AK+
Sbjct: 268 YGKEVDIWSAGIILYILLSGVPPFWAETEKGIFDAILEGH--IDFESQPWPSISSSAKDL 325
Query: 285 ILWALTVSPKRRPTATDLINDIWITSTEKSTTDLLPEIRKGFDARKEFRDAVEIVKLNNR 344
+ LT PKRR +A D++ W+ +++ P K+FR ++ KL
Sbjct: 326 VRRMLTADPKRRISAADVLQHPWLREGGEASDK--PIDSAVLSRMKQFRAMNKLKKL--- 380
Query: 345 IKKLKVLYENQDESD 359
LKV+ EN D +
Sbjct: 381 --ALKVIAENIDTEE 393
>At1g12580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 522
Score = 161 bits (407), Expect = 2e-39
Identities = 93/273 (34%), Positives = 146/273 (53%), Gaps = 6/273 (2%)
Query: 43 KSDYIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQL 102
K Y+ G+ LG G FGV+R +GE Q ++ + E++I+ +L
Sbjct: 41 KDRYVLGEQLGWGQFGVIRVCSDKLTGERLACKSISKDRLVTQD-DMKSIKLEIAIMAKL 99
Query: 103 -NHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYL 161
HPN+V K +E K+ ++V +L GGELF ++ + G++ EV A + K ++Q V++
Sbjct: 100 AGHPNVVNLKAVYEEKDSVHLVMELCAGGELFHKLEKYGRYSEVRARVLFKHLMQVVKFC 159
Query: 162 HQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLT 221
H IVHRDLKPENIL S SP+ + DFG+A +K E + GS Y+APEVL
Sbjct: 160 HDSGIVHRDLKPENILMATMSSSSPIKLADFGLATYIK-PGEKLSGTVGSPFYIAPEVL- 217
Query: 222 SSGHGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTA 281
+ G+ + D+WS GVI Y LL G PF ++ + + + F W+N++ A
Sbjct: 218 AGGYNQAADVWSAGVILYILLSGAPPFWGKTKSKIFDAVRAAD--LRFSAEPWDNITSYA 275
Query: 282 KEFILWALTVSPKRRPTATDLINDIWITSTEKS 314
K+ I L V P +R +A +++ W+ +S
Sbjct: 276 KDLIRGMLCVDPSQRLSADEVLAHSWMEQLSES 308
>CE12518 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 391
Score = 160 bits (406), Expect = 3e-39
Identities = 80/230 (34%), Positives = 136/230 (58%), Gaps = 3/230 (1%)
Query: 94 DELSILQQLNHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQ 153
+EL+IL +L+HP ++R ++ F+S K +IV Q+A+GGE++DR++ KG++ E +A +K
Sbjct: 111 NELNILSRLSHPFVIRLEEVFKSSSKLFIVMQMASGGEMYDRVVAKGRYSEEEARNALKM 170
Query: 154 ILQGVQYLHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMG 213
+L G+ YLH + HRDLKPEN+LY + ++ L+I DFG+A + NE + + G+
Sbjct: 171 LLTGLTYLHSIRVTHRDLKPENLLYADSRPEARLLITDFGLAYQATKPNETMTETCGTPE 230
Query: 214 YVAPEVLTSSGHGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPY 273
Y+APE+L + + D+W++GVI Y L+ G PF + + Y V++ +
Sbjct: 231 YIAPELLLRVPYTQKVDMWAVGVIAYILMSGIMPFDDDCRSRLYTHIITANY--VYYPQF 288
Query: 274 WNNVSKTAKEFILWALTVSPKRRPTATDLINDIWITSTEKSTTDLLPEIR 323
W+ S+ AK+F+ L + R +++ + W+T STT P R
Sbjct: 289 WSG-SELAKQFVDSLLETNSVERLSSSAAMKHEWLTGERPSTTQSRPPTR 337
>7295638 [T] KOG0603 Ribosomal protein S6 kinase
Length = 911
Score = 160 bits (406), Expect = 3e-39
Identities = 94/271 (34%), Positives = 142/271 (51%), Gaps = 8/271 (2%)
Query: 44 SDYIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQM-LYDELSILQQL 102
++Y + LG GTF V R +S ++ S ++E+ I+ +
Sbjct: 566 AEYNLLQELGRGTFSVCRLCEHRASKKHYAVKVIEKAAVAAASTSTSADCWEEVEIMLRY 625
Query: 103 -NHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYL 161
NHPNIV +E Y+V +L GGEL DRIL G+ CE +A +++ I V YL
Sbjct: 626 GNHPNIVTLYSVYEDAGSAYLVMELLKGGELLDRILAVGQMCESEASAVLRTIASAVAYL 685
Query: 162 HQRNIVHRDLKPENILYLN-KSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVL 220
H+ +VHRDLKP N++Y + + L + D G AK+L+ DN L+ + +VAPEVL
Sbjct: 686 HEHGVVHRDLKPSNMIYASMRQTPETLKLCDLGFAKQLRADNGLLMTPCYTANFVAPEVL 745
Query: 221 TSSGHGKPCDIWSIGVITYTLLCGYSPFLA---ESADGFIEECTSGQYPVVFHKPYWNNV 277
G+ CDIWS+GV+ Y +L G +PF + +S D ++ SGQ + F W +
Sbjct: 746 KRQGYDLACDIWSLGVLLYIMLSGRTPFASTPNDSPDVILKRIGSGQ--IDFTSSRWALI 803
Query: 278 SKTAKEFILWALTVSPKRRPTATDLINDIWI 308
S AKE + L + P+ RPTA ++ W+
Sbjct: 804 SVPAKELLRQMLHIVPENRPTAARILEHDWL 834
Score = 104 bits (260), Expect = 2e-22
Identities = 68/247 (27%), Positives = 119/247 (47%), Gaps = 5/247 (2%)
Query: 3 KKEPLSENNSRKPEEPEPVEGHKLTKLFNKVTGQPSSYVNKSDYIFGKTLGAGTFGVVRQ 62
++E + ++ E+ EP+ + +V + + S + + LG G+FG V
Sbjct: 156 RREGATGRSAPDLEDTEPLYETENEFELKEVIKEGHDKADPSQFELLRVLGEGSFGKVFL 215
Query: 63 ARCISSGENXXXXXXXXXXXXGQSVQLQMLY-DELSILQQLNHPNIVRFKDWFESKEKFY 121
R I + V+ ++ +E IL + H IVR F++ K Y
Sbjct: 216 VRKIIGKDAGTLYAMKVLKKATLKVKDRVRSTNERKILADVGHAFIVRLHYAFQTPGKLY 275
Query: 122 IVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRNIVHRDLKPENILYLNK 181
++ GG+LF R+ ++ F E D F + ++ + +LH I++RDLKPENIL
Sbjct: 276 LILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALAMNHLHTLGIIYRDLKPENILL--- 332
Query: 182 SDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSGHGKPCDIWSIGVITYTL 241
+ + + DFG++K+ D ++ + G++ Y+APE++ GH D WS GV+ Y +
Sbjct: 333 DEHGHIALTDFGLSKQPLDGSK-TYSFCGTVEYMAPEIVNRKGHDFAADWWSFGVLMYEM 391
Query: 242 LCGYSPF 248
L G PF
Sbjct: 392 LTGNLPF 398
>Hs7657526 [T] KOG0603 Ribosomal protein S6 kinase
Length = 745
Score = 160 bits (404), Expect = 4e-39
Identities = 95/279 (34%), Positives = 150/279 (53%), Gaps = 19/279 (6%)
Query: 46 YIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXX---GQSVQLQMLYDELSILQQL 102
Y + +G G++ V + RCI + N + +++ M Y +
Sbjct: 426 YELKEDIGVGSYSVCK--RCIHATTNMEFAVKIIDKSKRDPSEEIEILMRYGQ------- 476
Query: 103 NHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLH 162
HPNI+ KD F+ Y+VT L GGEL DRIL++ F E +A I+ I + V YLH
Sbjct: 477 -HPNIITLKDVFDDGRYVYLVTDLMKGGELLDRILKQKCFSEREASDILYVISKTVDYLH 535
Query: 163 QRNIVHRDLKPENILYLNKSDDSPLV-IGDFGIAKELKDDNELIHKAAGSMGYVAPEVLT 221
+ +VHRDLKP NILY+++S + + I DFG AK+L+ +N L+ + +VAPEVL
Sbjct: 536 CQGVVHRDLKPSNILYMDESASADSIRICDFGFAKQLRGENGLLLTPCYTANFVAPEVLM 595
Query: 222 SSGHGKPCDIWSIGVITYTLLCGYSPFL---AESADGFIEECTSGQYPVVFHKPYWNNVS 278
G+ CDIWS+GV+ YT+L GY+PF ++ + + +G++ + W+N+S
Sbjct: 596 QQGYDAACDIWSLGVLFYTMLAGYTPFANGPNDTPEEILLRIGNGKFSL--SGGNWDNIS 653
Query: 279 KTAKEFILWALTVSPKRRPTATDLINDIWITSTEKSTTD 317
AK+ + L + P +R TA ++ WIT ++ D
Sbjct: 654 DGAKDLLSHMLHMDPHQRYTAEQILKHSWITHRDQLPND 692
Score = 112 bits (281), Expect = 8e-25
Identities = 65/200 (32%), Positives = 105/200 (52%), Gaps = 4/200 (2%)
Query: 50 KTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYD-ELSILQQLNHPNIV 108
K LG G+FG V R + + V+ ++ E IL ++NHP IV
Sbjct: 77 KVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLKKASLKVRDRVRTKMERDILVEVNHPFIV 136
Query: 109 RFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRNIVH 168
+ F+++ K Y++ GG++F R+ ++ F E D F + ++ + +LHQ IV+
Sbjct: 137 KLHYAFQTEGKLYLILDFLRGGDVFTRLSKEVLFTEEDVKFYLAELALALDHLHQLGIVY 196
Query: 169 RDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSGHGKP 228
RDLKPENIL + + + DFG++KE D + + G++ Y+APEV+ GH +
Sbjct: 197 RDLKPENILL---DEIGHIKLTDFGLSKESVDQEKKAYSFCGTVEYMAPEVVNRRGHSQS 253
Query: 229 CDIWSIGVITYTLLCGYSPF 248
D WS GV+ + +L G PF
Sbjct: 254 ADWWSYGVLMFEMLTGTLPF 273
>Hs20479818 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 514
Score = 160 bits (404), Expect = 4e-39
Identities = 103/323 (31%), Positives = 173/323 (52%), Gaps = 21/323 (6%)
Query: 46 YIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNHP 105
Y FG+ LG G+FG+V +A + E G S +++L E++IL+ + H
Sbjct: 116 YTFGRILGKGSFGIVIEATDKET-ETKWAIKKVNKEKAGSSA-VKLLEREVNILKSVKHE 173
Query: 106 NIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRN 165
+I+ + FE+ +K Y+V +L GEL + + KG F E + +I++ + + YLH +
Sbjct: 174 HIIHLEQVFETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHNND 233
Query: 166 IVHRDLKPENILYL------NKSDDSPLVIGDFGIAKELKDDNE-LIHKAAGSMGYVAPE 218
IVHRDLK ENI+ N + + + DFG+A + + +E ++ G+ Y+APE
Sbjct: 234 IVHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQATCGTPIYMAPE 293
Query: 219 VLTSSGHGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVS 278
V+++ + + CDIWSIGV+ Y LL G PFLA S + E G+ + F WN++S
Sbjct: 294 VISAHDYSQQCDIWSIGVVMYMLLRGEPPFLASSEEKLFELIRKGE--LHFENAVWNSIS 351
Query: 279 KTAKEFILWALTVSPKRRPTATDLINDIWITSTEKST---TDLLPEIRKGFDARKEFRDA 335
AK + + V P R TA +L+++ W+T + S+ T++L + KE+++
Sbjct: 352 DCAKSVLKQLMKVDPAHRITAKELLDNQWLTGNKLSSVRPTNVL-------EMMKEWKNN 404
Query: 336 VEIVKLNNRIKKLKVLYENQDES 358
E V+ N +K K E + +S
Sbjct: 405 PESVEENTTEEKNKPSTEEKLKS 427
>At1g18890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 545
Score = 159 bits (403), Expect = 6e-39
Identities = 104/323 (32%), Positives = 162/323 (49%), Gaps = 17/323 (5%)
Query: 46 YIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQL-NH 104
YI G+ LG G FG+ + E +V ++ + E++I+ L H
Sbjct: 63 YILGRELGRGEFGITYLCTDRETHE-ALACKSISKRKLRTAVDIEDVRREVAIMSTLPEH 121
Query: 105 PNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQR 164
PN+V+ K +E E ++V +L GGELFDRI+ +G + E A + + I + V H
Sbjct: 122 PNVVKLKASYEDNENVHLVMELCEGGELFDRIVARGHYTERAAAAVARTIAEVVMMCHSN 181
Query: 165 NIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSG 224
++HRDLKPEN L+ NK ++SPL DFG++ K ++ + GS Y+APEVL
Sbjct: 182 GVMHRDLKPENFLFANKKENSPLKAIDFGLSVFFKPGDKFT-EIVGSPYYMAPEVL-KRD 239
Query: 225 HGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKEF 284
+G D+WS GVI Y LLCG PF AE+ G G + F + W +S++AK
Sbjct: 240 YGPGVDVWSAGVIIYILLCGVPPFWAETEQGVALAILRG--VLDFKRDPWPQISESAKSL 297
Query: 285 ILWALTVSPKRRPTATDLINDIWITSTEKSTTDLLPEIRKGFDARKEFRDAVEIVKLNNR 344
+ L P +R TA ++ WI + +K+ L +I R ++ + NR
Sbjct: 298 VKQMLDPDPTKRLTAQQVLAHPWIQNAKKAPNVPLGDI---------VRSRLKQFSMMNR 348
Query: 345 IKK--LKVLYENQDESDTDIEVN 365
KK L+V+ E+ + ++ N
Sbjct: 349 FKKKVLRVIAEHLSIQEVEVIKN 371
>At3g19100 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 599
Score = 159 bits (401), Expect = 1e-38
Identities = 101/270 (37%), Positives = 145/270 (53%), Gaps = 10/270 (3%)
Query: 49 GKTLGAGTFGVVRQARCISSGE---NXXXXXXXXXXXXGQSVQLQMLYDELSILQQLN-H 104
G+ +G G FG A+ GE ++ ++ + E+ IL+ L+ H
Sbjct: 147 GEEIGRGHFGYTCSAK-FKKGELKDQEVAVKVIPKSKMTSAISIEDVRREVKILRALSGH 205
Query: 105 PNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKG-KFCEVDAVFIVKQILQGVQYLHQ 163
N+V+F D FE YIV +L GGEL DRIL +G K+ E DA ++ QIL V + H
Sbjct: 206 QNLVQFYDAFEDNANVYIVMELCGGGELLDRILARGGKYSEDDAKAVLIQILNVVAFCHL 265
Query: 164 RNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSS 223
+ +VHRDLKPEN LY +K ++S L + DFG++ ++ D E ++ GS YVAPEVL S
Sbjct: 266 QGVVHRDLKPENFLYTSKEENSMLKVIDFGLSDFVRPD-ERLNDIVGSAYYVAPEVLHRS 324
Query: 224 GHGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKE 283
+ D+WSIGVI Y LLCG PF A + G F +P W ++S AK+
Sbjct: 325 -YTTEADVWSIGVIAYILLCGSRPFWARTESGIFRAVLKAD--PSFDEPPWPSLSFEAKD 381
Query: 284 FILWALTVSPKRRPTATDLINDIWITSTEK 313
F+ L P++R TA+ + WI +K
Sbjct: 382 FVKRLLYKDPRKRMTASQALMHPWIAGYKK 411
>Hs6005850 [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 543
Score = 158 bits (400), Expect = 1e-38
Identities = 107/331 (32%), Positives = 165/331 (49%), Gaps = 20/331 (6%)
Query: 3 KKEPLSENNSRKPEEPEPVEGHKLTKLFNKVTGQPSSYVN--KSDYIFGKTLGAGTFGVV 60
K+ PL+ N+ E + +K+ F+ S Y + +YI KTLG+G G V
Sbjct: 179 KRRPLNNNS----EIALSLSRNKVFVFFDLTVDDQSVYPKALRDEYIMSKTLGSGACGEV 234
Query: 61 RQA----RCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNHPNIVRFKDWFES 116
+ A C ++ + E+ IL++LNHP I++ K++F++
Sbjct: 235 KLAFERKTCKKVAIKIISKRKFAIGSAREADPALNVETEIEILKKLNHPCIIKIKNFFDA 294
Query: 117 KEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRNIVHRDLKPENI 176
E +YIV +L GGELFD+++ + E Q+L VQYLH+ I+HRDLKPEN+
Sbjct: 295 -EDYYIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENV 353
Query: 177 LYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTS---SGHGKPCDIWS 233
L ++ +D + I DFG +K L + L+ G+ Y+APEVL S +G+ + D WS
Sbjct: 354 LLSSQEEDCLIKITDFGHSKIL-GETSLMRTLCGTPTYLAPEVLVSVGTAGYNRAVDCWS 412
Query: 234 IGVITYTLLCGYSPFLAESAD-GFIEECTSGQYPVVFHKPYWNNVSKTAKEFILWALTVS 292
+GVI + L GY PF ++ TSG+Y F W VS+ A + + L V
Sbjct: 413 LGVILFICLSGYPPFSEHRTQVSLKDQITSGKYN--FIPEVWAEVSEKALDLVKKLLVVD 470
Query: 293 PKRRPTATDLINDIWITSTE--KSTTDLLPE 321
PK R T + + W+ + + DLL E
Sbjct: 471 PKARFTTEEALRHPWLQDEDMKRKFQDLLSE 501
>Hs4758700 [T] KOG0604 MAP kinase-activated protein kinase 2
Length = 382
Score = 158 bits (400), Expect = 1e-38
Identities = 114/341 (33%), Positives = 162/341 (47%), Gaps = 44/341 (12%)
Query: 36 QPSSYVNKSDYIFGK-TLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYD 94
+P Y DY K LG G G V + GQ L++LYD
Sbjct: 33 EPKKYAVTDDYQLSKQVLGLGVNGKVLEC---------------FHRRTGQKCALKLLYD 77
Query: 95 ELSILQQLNH-------PNIVRFKDWFES----KEKFYIVTQLATGGELFDRILEKGK-- 141
Q+++H P+IV D +E+ K I+ + GGELF RI E+G
Sbjct: 78 SPKARQEVDHHWQASGGPHIVCILDVYENMHHGKRCLLIIMECMEGGELFSRIQERGDQA 137
Query: 142 FCEVDAVFIVKQILQGVQYLHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDD 201
F E +A I++ I +Q+LH NI HRD+KPEN+LY +K D+ L + DFG AKE +
Sbjct: 138 FTEREAAEIMRDIGTAIQFLHSHNIAHRDVKPENLLYTSKEKDAVLKLTDFGFAKETTQN 197
Query: 202 NELIHKAAGSMGYVAPEVLTSSGHGKPCDIWSIGVITYTLLCGYSPFLAES----ADGFI 257
+ + YVAPEVL + K CD+WS+GVI Y LLCG+ PF + + + G
Sbjct: 198 --ALQTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGFPPFYSNTGQAISPGMK 255
Query: 258 EECTSGQYPVVFHKPYWNNVSKTAKEFILWALTVSPKRRPTATDLINDIWIT------ST 311
GQY F P W+ VS+ AK+ I L P R T T +N WI T
Sbjct: 256 RRIRLGQYG--FPNPEWSEVSEDAKQLIRLLLKTDPTERLTITQFMNHPWINQSMVVPQT 313
Query: 312 EKSTTDLLPEIRKGFD-ARKEFRDAVEIVKLNNRIKKLKVL 351
T +L E + +D ++E A+ ++++ K+K L
Sbjct: 314 PLHTARVLQEDKDHWDEVKEEMTSALATMRVDYDQVKIKDL 354
>Hs14916455 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 385
Score = 158 bits (400), Expect = 1e-38
Identities = 83/215 (38%), Positives = 131/215 (60%), Gaps = 3/215 (1%)
Query: 95 ELSILQQLNHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQI 154
ELS+L++++H IV+ + FE++++ Y+V +LATGGELFDR++ +G F E DAV I++ +
Sbjct: 108 ELSVLRRVSHRYIVQLMEIFETEDQVYMVMELATGGELFDRLIAQGSFTERDAVRILQMV 167
Query: 155 LQGVQYLHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKA-AGSMG 213
G++YLH I HR+LKPEN+LY + ++S ++I DFG+A K + K G+
Sbjct: 168 ADGIRYLHALQITHRNLKPENLLYYHPGEESKILITDFGLAYSGKKSGDWTMKTLCGTPE 227
Query: 214 YVAPEVLTSSGHGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPY 273
Y+APEVL + D+W++GVITY LL G+ PF ES + G+Y +
Sbjct: 228 YIAPEVLLRKPYTSAVDMWALGVITYALLSGFLPFDDESQTRLYRKILKGKYN--YTGEP 285
Query: 274 WNNVSKTAKEFILWALTVSPKRRPTATDLINDIWI 308
W ++S AK+FI L + R +A ++ W+
Sbjct: 286 WPSISHLAKDFIDKLLILEAGHRMSAGQALDHPWV 320
>At5g66210 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 523
Score = 158 bits (399), Expect = 2e-38
Identities = 101/273 (36%), Positives = 141/273 (50%), Gaps = 8/273 (2%)
Query: 46 YIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLN-H 104
Y GK LG G FG A +G+ + ++ + E+ IL L+ H
Sbjct: 62 YTIGKLLGHGQFGYTYVAIHRPNGDRVAVKRLDKSKMV-LPIAVEDVKREVQILIALSGH 120
Query: 105 PNIVRFKDWFESKEKFYIVTQLATGGELFDRILEK--GKFCEVDAVFIVKQILQGVQYLH 162
N+V+F + FE + YIV +L GGEL DRIL K ++ E DA +V+Q+L+ H
Sbjct: 121 ENVVQFHNAFEDDDYVYIVMELCEGGELLDRILSKKGNRYSEKDAAVVVRQMLKVAGECH 180
Query: 163 QRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTS 222
+VHRD+KPEN L+ + DSPL DFG++ +K + H GS YVAPEVL
Sbjct: 181 LHGLVHRDMKPENFLFKSAQLDSPLKATDFGLSDFIK-PGKRFHDIVGSAYYVAPEVLKR 239
Query: 223 SGHGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAK 282
G D+WSIGVITY LLCG PF + DG +E + P KP W +S +AK
Sbjct: 240 RS-GPESDVWSIGVITYILLCGRRPFWDRTEDGIFKEVLRNK-PDFSRKP-WATISDSAK 296
Query: 283 EFILWALTVSPKRRPTATDLINDIWITSTEKST 315
+F+ L P+ R TA ++ W+ +T
Sbjct: 297 DFVKKLLVKDPRARLTAAQALSHAWVREGGNAT 329
>At4g36070 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 536
Score = 158 bits (399), Expect = 2e-38
Identities = 117/371 (31%), Positives = 167/371 (44%), Gaps = 36/371 (9%)
Query: 12 SRKPEEPEPVEGHKLTKLFNKVT----------------------GQPSSYVNKSDYIFG 49
SR P P +G K+ NK G + N+ Y G
Sbjct: 17 SRNPNPDSPTQGKASEKVSNKNKKNTKKIQLRHQGGIPYGKRIDFGYAKDFDNR--YTIG 74
Query: 50 KTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLN-HPNIV 108
K LG G FG A ++G N Q ++++ + E+ ILQ L H N+V
Sbjct: 75 KLLGHGQFGFTYVATDNNNG-NRVAVKRIDKAKMTQPIEVEDVKREVKILQALGGHENVV 133
Query: 109 RFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRNIVH 168
F + FE K YIV +L GGEL DRIL ++ E DA +V+Q+L+ H R +VH
Sbjct: 134 GFHNAFEDKTYIYIVMELCDGGELLDRILAN-RYTEKDAAVVVRQMLKVAAECHLRGLVH 192
Query: 169 RDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSGHGKP 228
RD+KPEN L+ + + S L DFG++ +K + GS YVAPEVL G
Sbjct: 193 RDMKPENFLFKSTEEGSSLKATDFGLSDFIKPGVK-FQDIVGSAYYVAPEVLKRRS-GPE 250
Query: 229 CDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKEFILWA 288
D+WSIGVITY LLCG PF ++ DG E + F + W +S AK+F+
Sbjct: 251 SDVWSIGVITYILLCGRRPFWDKTQDGIFNEVMRKKPD--FREVPWPTISNGAKDFVKKL 308
Query: 289 LTVSPKRRPTATDLINDIWITSTEKSTTDLLPEIRKGFDARKEFRDAVEIVKLNNRIKKL 348
L P+ R TA ++ W+ +++ E+ R V+ +L +
Sbjct: 309 LVKEPRARLTAAQALSHSWVKEGGEAS-----EVPIDISVLNNMRQFVKFSRLKQIALRA 363
Query: 349 KVLYENQDESD 359
N+DE D
Sbjct: 364 LAKTINEDELD 374
>At4g09570 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 501
Score = 158 bits (399), Expect = 2e-38
Identities = 98/267 (36%), Positives = 140/267 (51%), Gaps = 6/267 (2%)
Query: 43 KSDYIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQL 102
+ Y+ GK LG G FG SS N + + ++ E+ I+ L
Sbjct: 22 RDHYLLGKKLGQGQFGTTYLCTEKSSSANYACKSIPKRKLVCRE-DYEDVWREIQIMHHL 80
Query: 103 N-HPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYL 161
+ HPN+VR K +E +IV ++ GGELFDRI+ KG F E +A ++K IL V+
Sbjct: 81 SEHPNVVRIKGTYEDSVFVHIVMEVCEGGELFDRIVSKGCFSEREAAKLIKTILGVVEAC 140
Query: 162 HQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLT 221
H ++HRDLKPEN L+ + SDD+ L DFG++ K + ++ GS YVAPEVL
Sbjct: 141 HSLGVMHRDLKPENFLFDSPSDDAKLKATDFGLSVFYK-PGQYLYDVVGSPYYVAPEVLK 199
Query: 222 SSGHGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTA 281
+G D+WS GVI Y LL G PF AE+ G + G+ + F W +S+ A
Sbjct: 200 KC-YGPEIDVWSAGVILYILLSGVPPFWAETESGIFRQILQGK--IDFKSDPWPTISEGA 256
Query: 282 KEFILWALTVSPKRRPTATDLINDIWI 308
K+ I L SPK+R +A + + WI
Sbjct: 257 KDLIYKMLDRSPKKRISAHEALCHPWI 283
>At1g35670 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 495
Score = 158 bits (399), Expect = 2e-38
Identities = 97/271 (35%), Positives = 141/271 (51%), Gaps = 6/271 (2%)
Query: 43 KSDYIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQL 102
+ Y+ GK LG G FG S+ N + + ++ E+ I+ L
Sbjct: 23 RDHYLLGKKLGQGQFGTTYLCTEKSTSANYACKSIPKRKLVCRE-DYEDVWREIQIMHHL 81
Query: 103 N-HPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYL 161
+ HPN+VR K +E +IV ++ GGELFDRI+ KG F E +AV ++K IL V+
Sbjct: 82 SEHPNVVRIKGTYEDSVFVHIVMEVCEGGELFDRIVSKGHFSEREAVKLIKTILGVVEAC 141
Query: 162 HQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLT 221
H ++HRDLKPEN L+ + DD+ L DFG++ K + ++ GS YVAPEVL
Sbjct: 142 HSLGVMHRDLKPENFLFDSPKDDAKLKATDFGLSVFYK-PGQYLYDVVGSPYYVAPEVLK 200
Query: 222 SSGHGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTA 281
+G D+WS GVI Y LL G PF AE+ G + G+ + F W +S+ A
Sbjct: 201 KC-YGPEIDVWSAGVILYILLSGVPPFWAETESGIFRQILQGK--LDFKSDPWPTISEAA 257
Query: 282 KEFILWALTVSPKRRPTATDLINDIWITSTE 312
K+ I L SPK+R +A + + WI +
Sbjct: 258 KDLIYKMLERSPKKRISAHEALCHPWIVDEQ 288
>At4g23650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 529
Score = 157 bits (397), Expect = 3e-38
Identities = 110/336 (32%), Positives = 165/336 (48%), Gaps = 18/336 (5%)
Query: 27 TKLFNKVTGQPSSYVNKSDYIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQS 86
T+ ++ G+P V ++ Y FG+ LG G FGV + + +
Sbjct: 60 TQQNGRILGRPMEEVRRT-YEFGRELGRGQFGVTYLVTHKETKQQVACKSIPTRRLVHKD 118
Query: 87 VQLQMLYDELSILQQLN-HPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEV 145
++ + E+ I+ L+ H NIV K +E + ++ +L GGELFDRI+ KG + E
Sbjct: 119 -DIEDVRREVQIMHHLSGHRNIVDLKGAYEDRHSVNLIMELCEGGELFDRIISKGLYSER 177
Query: 146 DAVFIVKQILQGVQYLHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELI 205
A + +Q++ V H ++HRDLKPEN L+L+K ++SPL DFG++ K ++
Sbjct: 178 AAADLCRQMVMVVHSCHSMGVMHRDLKPENFLFLSKDENSPLKATDFGLSVFFKPGDK-F 236
Query: 206 HKAAGSMGYVAPEVLTSSGHGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQY 265
GS YVAPEVL +G DIWS GVI Y LL G PF E+ G + GQ
Sbjct: 237 KDLVGSAYYVAPEVL-KRNYGPEADIWSAGVILYILLSGVPPFWGENETGIFDAILQGQ- 294
Query: 266 PVVFHKPYWNNVSKTAKEFILWALTVSPKRRPTATDLINDIWITSTEKSTTDLLPEIRKG 325
+ F W +S AK+ + L PK R TA +++N WI +++ P
Sbjct: 295 -LDFSADPWPALSDGAKDLVRKMLKYDPKDRLTAAEVLNHPWIREDGEASDK--PLDNAV 351
Query: 326 FDARKEFRDAVEIVKLNNRIKK--LKVLYENQDESD 359
K+FR N++KK LKV+ EN E +
Sbjct: 352 LSRMKQFR-------AMNKLKKMALKVIAENLSEEE 380
>At3g56760 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 577
Score = 157 bits (397), Expect = 3e-38
Identities = 107/312 (34%), Positives = 155/312 (49%), Gaps = 18/312 (5%)
Query: 10 NNSRKPEEPEPVEGHKLTKLFNKVTGQPSSYVNKSDYIFGKTLGAGTFGVVRQARCISSG 69
+ S KP E EG + +K G + S Y +G G FG C + G
Sbjct: 90 HGSVKPNEASIPEGSECEVGLDKKFGFSKQFA--SHYEIDGEVGRGHFGYT----CSAKG 143
Query: 70 ENXXXXXXXXX------XXXGQSVQLQMLYDELSILQQLN-HPNIVRFKDWFESKEKFYI 122
+ ++ ++ + E+ IL+ L H N+V+F D FE E YI
Sbjct: 144 KKGSLKGQDVAVKVIPKSKMTTAIAIEDVRREVKILRALTGHKNLVQFYDAFEDDENVYI 203
Query: 123 VTQLATGGELFDRILEKG-KFCEVDAVFIVKQILQGVQYLHQRNIVHRDLKPENILYLNK 181
V +L GGEL D+IL++G K+ EVDA ++ QIL V Y H + +VHRDLKPEN L+ K
Sbjct: 204 VMELCQGGELLDKILQRGGKYSEVDAKKVMIQILSVVAYCHLQGVVHRDLKPENFLFTTK 263
Query: 182 SDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSGHGKPCDIWSIGVITYTL 241
+ SPL DFG++ ++ D E ++ GS YVAPEVL + +G D+WSIGVI Y L
Sbjct: 264 DESSPLKAIDFGLSDYVRPD-ERLNDIVGSAYYVAPEVLHRT-YGTEADMWSIGVIAYIL 321
Query: 242 LCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKEFILWALTVSPKRRPTATD 301
LCG PF A S G + F + W ++S A +F+ L ++R TA
Sbjct: 322 LCGSRPFWARSESGIFRAVLKAE--PNFEEAPWPSLSPDAVDFVKRLLNKDYRKRLTAAQ 379
Query: 302 LINDIWITSTEK 313
+ W+ + +
Sbjct: 380 ALCHPWLVGSHE 391
>At1g50700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 521
Score = 157 bits (397), Expect = 3e-38
Identities = 106/315 (33%), Positives = 158/315 (49%), Gaps = 13/315 (4%)
Query: 46 YIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLN-H 104
Y K LG G FGV S+G+ + + M E+ I+Q L+
Sbjct: 73 YTLSKELGRGQFGVTYLCTEKSTGKRFACKSISKKKLVTKGDKEDMRR-EIQIMQHLSGQ 131
Query: 105 PNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQR 164
PNIV FK +E ++ +V +L GGELFDRIL KG + E A + +QI+ V H
Sbjct: 132 PNIVEFKGAYEDEKAVNLVMELCAGGELFDRILAKGHYSERAAASVCRQIVNVVNICHFM 191
Query: 165 NIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSG 224
++HRDLKPEN L +K + + + DFG++ + ++ + GS YVAPEVL
Sbjct: 192 GVMHRDLKPENFLLSSKDEKALIKATDFGLSVFI-EEGRVYKDIVGSAYYVAPEVL-KRR 249
Query: 225 HGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKEF 284
+GK DIWS G+I Y LL G PF AE+ G + G+ + F W ++S +AK+
Sbjct: 250 YGKEIDIWSAGIILYILLSGVPPFWAETEKGIFDAILEGE--IDFESQPWPSISNSAKDL 307
Query: 285 ILWALTVSPKRRPTATDLINDIWITSTEKSTTDLLPEIRKGFDARKEFRDAVEIVKLNNR 344
+ LT PKRR +A +++ W+ +++ P K+FR ++ KL
Sbjct: 308 VRRMLTQDPKRRISAAEVLKHPWLREGGEASDK--PIDSAVLSRMKQFRAMNKLKKL--- 362
Query: 345 IKKLKVLYENQDESD 359
LKV+ EN D +
Sbjct: 363 --ALKVIAENIDTEE 375
>YDL101c [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 513
Score = 157 bits (396), Expect = 4e-38
Identities = 102/337 (30%), Positives = 166/337 (48%), Gaps = 34/337 (10%)
Query: 1 MFKKEPLSENNSRKPEEPEPVEGHKLTKLFNKVTGQPSSYVNKSDYIFGKTLGAGTFGVV 60
+FKK +S +S+ + KL K +P S+ +K Y+ GK LGAG + +V
Sbjct: 165 VFKKPQISATSSQNATTSAAIR--KLNKT------RPVSFFDK--YLLGKELGAGHYALV 214
Query: 61 RQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNHPNIVRFKDWF-----E 115
++A+ +G+ Q Q +E +IL ++ HPNIV D F +
Sbjct: 215 KEAKNKKTGQQVAVKIFHAQQNDDQKKNKQFR-EETNILMRVQHPNIVNLLDSFVEPISK 273
Query: 116 SKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRNIVHRDLKPEN 175
S+ + Y+V + GELF+RI+ K + ++ + KQ+L G++YLH++NI+HRD+KPEN
Sbjct: 274 SQIQKYLVLEKIDDGELFERIVRKTCLRQDESKALFKQLLTGLKYLHEQNIIHRDIKPEN 333
Query: 176 ILYLNKSDDSP----------------LVIGDFGIAKELKDDNELIHKAAGSMGYVAPEV 219
IL ++P + I DFG+AK + + + G+ YVAPEV
Sbjct: 334 ILLNITRRENPSQVQLGPWDEDEIDIQVKIADFGLAK-FTGEMQFTNTLCGTPSYVAPEV 392
Query: 220 LTSSGHGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSK 279
LT G+ D+WS GVI Y LCG+ PF + ++E Q F+ PYW+ +
Sbjct: 393 LTKKGYTSKVDLWSAGVILYVCLCGFPPFSDQLGPPSLKEQIL-QAKYAFYSPYWDKIDD 451
Query: 280 TAKEFILWALTVSPKRRPTATDLINDIWITSTEKSTT 316
+ I L ++P R + +N W ++ ++
Sbjct: 452 SVLHLISNLLVLNPDERYNIDEALNHPWFNDIQQQSS 488
>At5g23580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 490
Score = 157 bits (396), Expect = 4e-38
Identities = 94/267 (35%), Positives = 143/267 (53%), Gaps = 6/267 (2%)
Query: 43 KSDYIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQL 102
+ +Y G+ LG G FG +G+ Q +L E+ I+ L
Sbjct: 19 EDNYFLGQVLGQGQFGTTFLCTHKQTGQKLACKSIPKRKLLCQEDYDDVLR-EIQIMHHL 77
Query: 103 N-HPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYL 161
+ +PN+VR + +E + ++V +L GGELFDRI+++G + E +A ++K I+ V+
Sbjct: 78 SEYPNVVRIESAYEDTKNVHLVMELCEGGELFDRIVKRGHYSEREAAKLIKTIVGVVEAC 137
Query: 162 HQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLT 221
H +VHRDLKPEN L+ + +D+ L DFG++ E + GS YVAPEVL
Sbjct: 138 HSLGVVHRDLKPENFLFSSSDEDASLKSTDFGLS-VFCTPGEAFSELVGSAYYVAPEVL- 195
Query: 222 SSGHGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTA 281
+G CD+WS GVI Y LLCG+ PF AES G + G+ + F W ++S++A
Sbjct: 196 HKHYGPECDVWSAGVILYILLCGFPPFWAESEIGIFRKILQGK--LEFEINPWPSISESA 253
Query: 282 KEFILWALTVSPKRRPTATDLINDIWI 308
K+ I L +PK+R TA ++ WI
Sbjct: 254 KDLIKKMLESNPKKRLTAHQVLCHPWI 280
>At3g50530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 601
Score = 157 bits (396), Expect = 4e-38
Identities = 109/304 (35%), Positives = 156/304 (50%), Gaps = 15/304 (4%)
Query: 10 NNSRKPEEPEPVEGHKLTKLFNKVTGQPSSYVNKSDYIFGKTLGAGTFGVVRQARCISSG 69
N+S PE E EG + +K G S+ +K Y G +G G FG A+ G
Sbjct: 117 NSSAIPEGSE-AEGGGVG--LDKSFGFSKSFASK--YELGDEVGRGHFGYTCAAK-FKKG 170
Query: 70 ENXXXXXXXXXXXXGQ---SVQLQMLYDELSILQQLN-HPNIVRFKDWFESKEKFYIVTQ 125
+N + ++ ++ + E+ IL+ L+ H N+ F D +E + YIV +
Sbjct: 171 DNKGQQVAVKVIPKAKMTTAIAIEDVRREVKILRALSGHNNLPHFYDAYEDHDNVYIVME 230
Query: 126 LATGGELFDRILEKG-KFCEVDAVFIVKQILQGVQYLHQRNIVHRDLKPENILYLNKSDD 184
L GGEL DRIL +G K+ E DA ++ QIL V + H + +VHRDLKPEN L+ +K D
Sbjct: 231 LCEGGELLDRILSRGGKYTEEDAKTVMIQILNVVAFCHLQGVVHRDLKPENFLFTSKEDT 290
Query: 185 SPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSGHGKPCDIWSIGVITYTLLCG 244
S L DFG++ ++ D E ++ GS YVAPEVL S + DIWS+GVI Y LLCG
Sbjct: 291 SQLKAIDFGLSDYVRPD-ERLNDIVGSAYYVAPEVLHRS-YSTEADIWSVGVIVYILLCG 348
Query: 245 YSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKEFILWALTVSPKRRPTATDLIN 304
PF A + G F P W +S A++F+ L P++R TA ++
Sbjct: 349 SRPFWARTESGIFRAVLKAD--PSFDDPPWPLLSSEARDFVKRLLNKDPRKRLTAAQALS 406
Query: 305 DIWI 308
WI
Sbjct: 407 HPWI 410
>At5g39440 [T] KOG0583 Serine/threonine protein kinase
Length = 494
Score = 156 bits (395), Expect = 5e-38
Identities = 92/266 (34%), Positives = 142/266 (52%), Gaps = 11/266 (4%)
Query: 45 DYIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNH 104
+Y GKTLG G+F V+ A +++G +++++ E+ IL+ L H
Sbjct: 18 NYRIGKTLGHGSFAKVKLALHVATGHKVAIKILNRSKIKNMGIEIKV-QREIKILRFLMH 76
Query: 105 PNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQR 164
P+I+R + E+ Y+V + GELFD I+EKGK E +A + +QI+ GV+Y H+
Sbjct: 77 PHIIRQYEVIETPNDIYVVMEYVKSGELFDYIVEKGKLQEDEARHLFQQIISGVEYCHRN 136
Query: 165 NIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSG 224
IVHRDLKPEN+L ++ + + I DFG++ + D + + GS Y APEV++
Sbjct: 137 MIVHRDLKPENVLLDSQCN---IKIVDFGLS-NVMHDGHFLKTSCGSPNYAAPEVISGKP 192
Query: 225 HGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKEF 284
+G DIWS GVI Y LLCG PF E+ E+ G Y + N++S A++
Sbjct: 193 YGPDVDIWSCGVILYALLCGTLPFDDENIPNVFEKIKRGMYTLP------NHLSHFARDL 246
Query: 285 ILWALTVSPKRRPTATDLINDIWITS 310
I L V P R + T++ W +
Sbjct: 247 IPRMLMVDPTMRISITEIRQHPWFNN 272
>At1g49580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 606
Score = 154 bits (390), Expect = 2e-37
Identities = 100/265 (37%), Positives = 141/265 (52%), Gaps = 10/265 (3%)
Query: 49 GKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQ---SVQLQMLYDELSILQQLN-H 104
G+ +G G FG A+ GE + ++ ++ + E+ ILQ L+ H
Sbjct: 153 GEEIGRGHFGYTCSAK-FKKGELKGQVVAVKIIPKSKMTTAIAIEDVRREVKILQALSGH 211
Query: 105 PNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKG-KFCEVDAVFIVKQILQGVQYLHQ 163
N+V+F D FE YI +L GGEL DRIL +G K+ E DA ++ QIL V + H
Sbjct: 212 KNLVQFYDAFEDNANVYIAMELCEGGELLDRILARGGKYSENDAKPVIIQILNVVAFCHF 271
Query: 164 RNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSS 223
+ +VHRDLKPEN LY +K ++S L DFG++ ++ D E ++ GS YVAPEVL S
Sbjct: 272 QGVVHRDLKPENFLYTSKEENSQLKAIDFGLSDFVRPD-ERLNDIVGSAYYVAPEVLHRS 330
Query: 224 GHGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKE 283
+ D+WSIGVI Y LLCG PF A + G F +P W +S AK+
Sbjct: 331 -YTTEADVWSIGVIAYILLCGSRPFWARTESGIFRAVLKAD--PSFDEPPWPFLSSDAKD 387
Query: 284 FILWALTVSPKRRPTATDLINDIWI 308
F+ L P+RR +A+ + WI
Sbjct: 388 FVKRLLFKDPRRRMSASQALMHPWI 412
>At1g30270 [T] KOG0583 Serine/threonine protein kinase
Length = 480
Score = 154 bits (390), Expect = 2e-37
Identities = 90/270 (33%), Positives = 139/270 (51%), Gaps = 11/270 (4%)
Query: 46 YIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNHP 105
Y G+TLG GTF V+ AR + +G+N ++ + + E+S ++ + HP
Sbjct: 31 YELGRTLGEGTFAKVKFARNVENGDNVAIKVIDKEKVL-KNKMIAQIKREISTMKLIKHP 89
Query: 106 NIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRN 165
N++R + SK K Y V + TGGELFD+I G+ E +A +Q++ V Y H R
Sbjct: 90 NVIRMFEVMASKTKIYFVLEFVTGGELFDKISSNGRLKEDEARKYFQQLINAVDYCHSRG 149
Query: 166 IVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSGH 225
+ HRDLKPEN+L + L + DFG++ + ++ L+H G+ YVAPEV+ + G+
Sbjct: 150 VYHRDLKPENLLL---DANGALKVSDFGLSALPQQEDGLLHTTCGTPNYVAPEVINNKGY 206
Query: 226 -GKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKEF 284
G D+WS GVI + L+ GY PF D + + F P W S +AK+
Sbjct: 207 DGAKADLWSCGVILFVLMAGYLPF----EDSNLTSLYKKIFKAEFTCPPW--FSASAKKL 260
Query: 285 ILWALTVSPKRRPTATDLINDIWITSTEKS 314
I L +P R T ++I + W K+
Sbjct: 261 IKRILDPNPATRITFAEVIENEWFKKGYKA 290
>At3g10660 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 646
Score = 154 bits (388), Expect = 3e-37
Identities = 105/340 (30%), Positives = 164/340 (47%), Gaps = 15/340 (4%)
Query: 3 KKEPLSENNSR---KPEEPEPVEGHKLTKLFNKVTGQPSSYVNKSDYIFGKTLGAGTFGV 59
K E SE +P++P+ + L + Q + K Y G+ LG G FG
Sbjct: 140 KPETTSETKPETKAEPQKPKHMRRVSSAGLRTESVLQRKTENFKEFYSLGRKLGQGQFGT 199
Query: 60 VRQARCISSGE-NXXXXXXXXXXXXGQSVQLQMLYDELSILQQL-NHPNIVRFKDWFESK 117
C+ G N ++ + E+ I+ L HPN++ K +E
Sbjct: 200 T--FLCLEKGTGNEYACKSISKRKLLTDEDVEDVRREIQIMHHLAGHPNVISIKGAYEDV 257
Query: 118 EKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRNIVHRDLKPENIL 177
++V +L +GGELFDRI+++G + E A + + I+ ++ H ++HRDLKPEN L
Sbjct: 258 VAVHLVMELCSGGELFDRIIQRGHYTERKAAELARTIVGVLEACHSLGVMHRDLKPENFL 317
Query: 178 YLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSGHGKPCDIWSIGVI 237
++++ +DS L DFG++ K D E+ GS YVAPEVL +G D+WS GVI
Sbjct: 318 FVSREEDSLLKTIDFGLSMFFKPD-EVFTDVVGSPYYVAPEVLRKR-YGPESDVWSAGVI 375
Query: 238 TYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKEFILWALTVSPKRRP 297
Y LL G PF AE+ G E+ G + F W ++S++AK+ + L PKRR
Sbjct: 376 VYILLSGVPPFWAETEQGIFEQVLHGD--LDFSSDPWPSISESAKDLVRKMLVRDPKRRL 433
Query: 298 TATDLINDIWI----TSTEKSTTDLLPEIRKGFDARKEFR 333
TA ++ W+ + +K + K F A +F+
Sbjct: 434 TAHQVLCHPWVQIDGVAPDKPLDSAVLSRMKQFSAMNKFK 473
>YGL158w [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 512
Score = 152 bits (383), Expect = 1e-36
Identities = 82/229 (35%), Positives = 127/229 (54%), Gaps = 25/229 (10%)
Query: 103 NHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLH 162
N+P+ +F + ES +Y+VT+L TGGE+FDRI++ F E A ++ Q+ ++++H
Sbjct: 192 NNPHCTKFIAFQESANYYYLVTELVTGGEIFDRIVQLTCFSEDLARHVITQVAIAIKHMH 251
Query: 163 QRNIVHRDLKPENILY-----------LNKSDDSPLVIG----------DFGIAKELKDD 201
IVHRD+KPEN+L+ + K D+ L +G DFG+AK+L+
Sbjct: 252 YMGIVHRDVKPENLLFEPIPFYGLDGDMQKEDEFTLGVGGGGIGLVKLMDFGLAKKLR-- 309
Query: 202 NELIHKAAGSMGYVAPEVLTSSGHGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECT 261
N G++ YVA EV TS + D+WSIG + +TLLCGY PF ++ +++ +
Sbjct: 310 NNTAKTPCGTIEYVASEVFTSKRYSMKVDMWSIGCVLFTLLCGYPPFYEKNEKTLLKKIS 369
Query: 262 SGQYPVVFHKPYWNNVSKTAKEFILWALTVSPKRRPTATDLINDIWITS 310
G Y F P+W+N+S AK + L V P +R D +ND W+ S
Sbjct: 370 RGDYE--FLAPWWDNISSGAKNAVTHLLEVDPNKRYDIDDFLNDPWLNS 416
>At2g41140 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 576
Score = 152 bits (383), Expect = 1e-36
Identities = 105/310 (33%), Positives = 153/310 (48%), Gaps = 18/310 (5%)
Query: 12 SRKPEEPEPVEGHKLTKLFNKVTGQPSSYVNKSDYIFGKTLGAGTFGVVRQARCISSGEN 71
S KP E EG + +K G + S Y +G G FG C + G+
Sbjct: 91 SVKPNEVSIPEGKECEIGLDKSFGFSKQFA--SHYEIDGEVGRGHFGYT----CSAKGKK 144
Query: 72 XXXXXXXXX------XXXGQSVQLQMLYDELSILQQLN-HPNIVRFKDWFESKEKFYIVT 124
++ ++ + E+ +L+ L H N+V+F D FE E YIV
Sbjct: 145 GSLKGQEVAVKVIPKSKMTTAIAIEDVSREVKMLRALTGHKNLVQFYDAFEDDENVYIVM 204
Query: 125 QLATGGELFDRILEKG-KFCEVDAVFIVKQILQGVQYLHQRNIVHRDLKPENILYLNKSD 183
+L GGEL D+IL++G K+ E DA ++ QIL V Y H + +VHRDLKPEN L+ K +
Sbjct: 205 ELCKGGELLDKILQRGGKYSEDDAKKVMVQILSVVAYCHLQGVVHRDLKPENFLFSTKDE 264
Query: 184 DSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSGHGKPCDIWSIGVITYTLLC 243
SPL DFG++ +K D E ++ GS YVAPEVL + +G D+WSIGVI Y LLC
Sbjct: 265 TSPLKAIDFGLSDYVKPD-ERLNDIVGSAYYVAPEVLHRT-YGTEADMWSIGVIAYILLC 322
Query: 244 GYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKEFILWALTVSPKRRPTATDLI 303
G PF A + G + F + W ++S A +F+ L ++R TA +
Sbjct: 323 GSRPFWARTESGIFRAVLKAE--PNFEEAPWPSLSPEAVDFVKRLLNKDYRKRLTAAQAL 380
Query: 304 NDIWITSTEK 313
W+ + +
Sbjct: 381 CHPWLVGSHE 390
>Hs19923570 [T] KOG0603 Ribosomal protein S6 kinase
Length = 733
Score = 150 bits (380), Expect = 3e-36
Identities = 85/225 (37%), Positives = 129/225 (56%), Gaps = 9/225 (4%)
Query: 94 DELSILQQLN-HPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVK 152
+E+ IL + HPNI+ KD ++ + Y+V +L GGEL DRIL + F E +A ++
Sbjct: 455 EEIEILLRYGQHPNIITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLC 514
Query: 153 QILQGVQYLHQRNIVHRDLKPENILYLNKSDDSPLV-IGDFGIAKELKDDNELIHKAAGS 211
I + + YLH + +VHRDLKP NILY ++S + + DFG AK+L+ N L+ +
Sbjct: 515 TITKTMDYLHSQGVVHRDLKPSNILYRDESGSPESIRVCDFGFAKQLRAGNGLLMTPCYT 574
Query: 212 MGYVAPEVLTSSGHGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECT----SGQYPV 267
+VAPEVL G+ CDIWS+G++ YT+L G++PF A D EE SG+Y
Sbjct: 575 ANFVAPEVLKRQGYDAACDIWSLGILLYTMLAGFTPF-ANGPDDTPEEILARIGSGKY-- 631
Query: 268 VFHKPYWNNVSKTAKEFILWALTVSPKRRPTATDLINDIWITSTE 312
W+++S AK+ + L V P +R TA ++ W+ + E
Sbjct: 632 ALSGGNWDSISDAAKDVVSKMLHVDPHQRLTAMQVLKHPWVVNRE 676
Score = 115 bits (288), Expect = 1e-25
Identities = 64/200 (32%), Positives = 106/200 (53%), Gaps = 4/200 (2%)
Query: 50 KTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYD-ELSILQQLNHPNIV 108
K LG G++G V R + + V+ ++ E IL ++NHP IV
Sbjct: 63 KVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVRSKMERDILAEVNHPFIV 122
Query: 109 RFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRNIVH 168
+ F+++ K Y++ GG+LF R+ ++ F E D F + ++ + +LH I++
Sbjct: 123 KLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGIIY 182
Query: 169 RDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSGHGKP 228
RDLKPENIL ++ + I DFG++KE D ++ + G++ Y+APEV+ GH +
Sbjct: 183 RDLKPENILL---DEEGHIKITDFGLSKEAIDHDKRAYSFCGTIEYMAPEVVNRRGHTQS 239
Query: 229 CDIWSIGVITYTLLCGYSPF 248
D WS GV+ + +L G PF
Sbjct: 240 ADWWSFGVLMFEMLTGSLPF 259
>Hs14589904 [T] KOG0604 MAP kinase-activated protein kinase 2
Length = 400
Score = 150 bits (380), Expect = 3e-36
Identities = 98/262 (37%), Positives = 141/262 (53%), Gaps = 20/262 (7%)
Query: 105 PNIVRFKDWFES----KEKFYIVTQLATGGELFDRILEKGK--FCEVDAVFIVKQILQGV 158
P+IVR D +E+ ++ IV + GGELF RI ++G F E +A I+K I + +
Sbjct: 115 PDIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAI 174
Query: 159 QYLHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPE 218
QYLH NI HRD+KPEN+LY +K ++ L + DFG AKE N L + YVAPE
Sbjct: 175 QYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLT-TPCYTPYYVAPE 233
Query: 219 VLTSSGHGKPCDIWSIGVITYTLLCGYSPFLAES----ADGFIEECTSGQYPVVFHKPYW 274
VL + K CD+WS+GVI Y LLCGY PF + + G GQY F P W
Sbjct: 234 VLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYE--FPNPEW 291
Query: 275 NNVSKTAKEFILWALTVSPKRRPTATDLINDIWITSTEK------STTDLLPEIRKGF-D 327
+ VS+ K I L P +R T T+ +N WI + K T+ +L E ++ + D
Sbjct: 292 SEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWED 351
Query: 328 ARKEFRDAVEIVKLNNRIKKLK 349
++E A+ ++++ K+K
Sbjct: 352 VKEEMTSALATMRVDYEQIKIK 373
>At5g04870 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 610
Score = 150 bits (379), Expect = 3e-36
Identities = 99/325 (30%), Positives = 159/325 (48%), Gaps = 10/325 (3%)
Query: 14 KPEEPEPVEGHKLTKLFNKVTGQPSSYVNKSDYIFGKTLGAGTFGVVRQARCISSGENXX 73
KP++P+ ++ L + Q + K Y G+ LG G FG ++G+
Sbjct: 118 KPKKPKHMKRVSSAGLRTESVLQRKTENFKEFYSLGRKLGQGQFGTTFLCVEKTTGKEFA 177
Query: 74 XXXXXXXXXXGQSVQLQMLYDELSILQQL-NHPNIVRFKDWFESKEKFYIVTQLATGGEL 132
++ + E+ I+ L HPN++ K +E ++V + GGEL
Sbjct: 178 CKSIAKRKLLTDE-DVEDVRREIQIMHHLAGHPNVISIKGAYEDVVAVHLVMECCAGGEL 236
Query: 133 FDRILEKGKFCEVDAVFIVKQILQGVQYLHQRNIVHRDLKPENILYLNKSDDSPLVIGDF 192
FDRI+++G + E A + + I+ V+ H ++HRDLKPEN L+++K +DS L DF
Sbjct: 237 FDRIIQRGHYTERKAAELTRTIVGVVEACHSLGVMHRDLKPENFLFVSKHEDSLLKTIDF 296
Query: 193 GIAKELKDDNELIHKAAGSMGYVAPEVLTSSGHGKPCDIWSIGVITYTLLCGYSPFLAES 252
G++ K D ++ GS YVAPEVL +G D+WS GVI Y LL G PF AE+
Sbjct: 297 GLSMFFKPD-DVFTDVVGSPYYVAPEVLRKR-YGPEADVWSAGVIVYILLSGVPPFWAET 354
Query: 253 ADGFIEECTSGQYPVVFHKPYWNNVSKTAKEFILWALTVSPKRRPTATDLINDIWI---- 308
G E+ G + F W ++S++AK+ + L PK+R TA ++ W+
Sbjct: 355 EQGIFEQVLHGD--LDFSSDPWPSISESAKDLVRKMLVRDPKKRLTAHQVLCHPWVQVDG 412
Query: 309 TSTEKSTTDLLPEIRKGFDARKEFR 333
+ +K + K F A +F+
Sbjct: 413 VAPDKPLDSAVLSRMKQFSAMNKFK 437
>At2g26980 [T] KOG0583 Serine/threonine protein kinase
Length = 441
Score = 150 bits (379), Expect = 3e-36
Identities = 93/272 (34%), Positives = 144/272 (52%), Gaps = 15/272 (5%)
Query: 46 YIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNHP 105
Y G+T+G GTF V+ AR +GE + Q + E++ ++ + HP
Sbjct: 14 YEVGRTIGEGTFAKVKFARNSETGEPVALKILDKEKVLKHKMAEQ-IRREIATMKLIKHP 72
Query: 106 NIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRN 165
N+V+ + SK K +I+ + TGGELFD+I+ G+ E +A +Q++ V Y H R
Sbjct: 73 NVVQLYEVMASKTKIFIILEYVTGGELFDKIVNDGRMKEDEARRYFQQLIHAVDYCHSRG 132
Query: 166 IVHRDLKPENILYLNKSDDSPLVIGDFG---IAKELKDDNELIHKAAGSMGYVAPEVLTS 222
+ HRDLKPEN+L + + L I DFG ++++++DD L+H + G+ YVAPEVL
Sbjct: 133 VYHRDLKPENLLLDSYGN---LKISDFGLSALSQQVRDDG-LLHTSCGTPNYVAPEVLND 188
Query: 223 SGH-GKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTA 281
G+ G D+WS GV+ Y LL GY PF + ++ +SG+ F+ P W +S A
Sbjct: 189 RGYDGATADMWSCGVVLYVLLAGYLPFDDSNLMNLYKKISSGE----FNCPPW--LSLGA 242
Query: 282 KEFILWALTVSPKRRPTATDLINDIWITSTEK 313
+ I L +P R T ++ D W K
Sbjct: 243 MKLITRILDPNPMTRVTPQEVFEDEWFKKDYK 274
>At1g01140 [T] KOG0583 Serine/threonine protein kinase
Length = 447
Score = 150 bits (379), Expect = 3e-36
Identities = 91/275 (33%), Positives = 144/275 (52%), Gaps = 15/275 (5%)
Query: 37 PSSYVNKSDYIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDEL 96
P+S +Y G+TLG G+F V+ A+ +G+ + ++ L E+
Sbjct: 10 PASRTRVGNYEMGRTLGEGSFAKVKYAKNTVTGDQAAIKILDREKVFRHKM-VEQLKREI 68
Query: 97 SILQQLNHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQ 156
S ++ + HPN+V + SK K YIV +L GGELFD+I ++G+ E +A +Q++
Sbjct: 69 STMKLIKHPNVVEIIEVMASKTKIYIVLELVNGGELFDKIAQQGRLKEDEARRYFQQLIN 128
Query: 157 GVQYLHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGI---AKELKDDNELIHKAAGSMG 213
V Y H R + HRDLKPEN++ + L + DFG+ ++++++D L+H A G+
Sbjct: 129 AVDYCHSRGVYHRDLKPENLIL---DANGVLKVSDFGLSAFSRQVREDG-LLHTACGTPN 184
Query: 214 YVAPEVLTSSGH-GKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKP 272
YVAPEVL+ G+ G D+WS GVI + L+ GY PF + + + F P
Sbjct: 185 YVAPEVLSDKGYDGAAADVWSCGVILFVLMAGYLPFDEPNLMTLYKRICKAE----FSCP 240
Query: 273 YWNNVSKTAKEFILWALTVSPKRRPTATDLINDIW 307
W S+ AK I L +P R + +L+ D W
Sbjct: 241 PW--FSQGAKRVIKRILEPNPITRISIAELLEDEW 273
>Hs22062450 [R] KOG0586 Serine/threonine protein kinase
Length = 787
Score = 149 bits (377), Expect = 6e-36
Identities = 103/314 (32%), Positives = 158/314 (49%), Gaps = 23/314 (7%)
Query: 4 KEPLSENNSRKPEEPEPVEGH---KLTKLFNKVTGQPSS-----YVNKSDYIFGKTLGAG 55
+ PL N R E+P GH K + N + G+ S+ + +Y KT+G G
Sbjct: 5 RTPLPTLNERDTEQP--TLGHLDSKPSSKSNMIRGRNSATSADEQPHIGNYRLLKTIGKG 62
Query: 56 TFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNHPNIVRFKDWFE 115
F V+ AR I +G+ S LQ L+ E+ I++ LNHPNIV+ + E
Sbjct: 63 NFAKVKLARHILTGKEVAVKIIDKTQLNSSS--LQKLFREVRIMKVLNHPNIVKLFEVIE 120
Query: 116 SKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRNIVHRDLKPEN 175
+++ Y+V + A+GGE+FD ++ G+ E +A +QI+ VQY HQ+ IVHRDLK EN
Sbjct: 121 TEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAEN 180
Query: 176 ILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSGH-GKPCDIWSI 234
+L D + I DFG + E N+L GS Y APE+ + G D+WS+
Sbjct: 181 LLL---DADMNIKIADFGFSNEFTFGNKL-DTFCGSPPYAAPELFQGKKYDGPEVDVWSL 236
Query: 235 GVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKEFILWALTVSPK 294
GVI YTL+ G PF ++ E G+Y + F+ +S + + L ++P
Sbjct: 237 GVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFY------MSTDCENLLKKFLILNPS 290
Query: 295 RRPTATDLINDIWI 308
+R T ++ D W+
Sbjct: 291 KRGTLEQIMKDRWM 304
>CE27768 [R] KOG0586 Serine/threonine protein kinase
Length = 1096
Score = 149 bits (377), Expect = 6e-36
Identities = 89/269 (33%), Positives = 142/269 (52%), Gaps = 13/269 (4%)
Query: 41 VNKSDYIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQ 100
V+ Y KT+G G F V+ A+ + +G S LQ L+ E+ I++
Sbjct: 117 VHVGKYKLLKTIGKGNFAKVKLAKHVITGHEVAIKIIDKTALNPSS--LQKLFREVKIMK 174
Query: 101 QLNHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQY 160
QL+HPNIV+ E+++ Y+V + A+GGE+FD ++ G+ E +A +QI+ VQY
Sbjct: 175 QLDHPNIVKLYQVMETEQTLYLVLEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQY 234
Query: 161 LHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVL 220
LH +NI+HRDLK EN+L D + I DFG + N+L GS Y APE+
Sbjct: 235 LHSKNIIHRDLKAENLLL---DQDMNIKIADFGFSNTFSLGNKL-DTFCGSPPYAAPELF 290
Query: 221 TSSGH-GKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSK 279
+ + G D+WS+GVI YTL+ G PF ++ E G+Y + F+ +S
Sbjct: 291 SGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFY------MST 344
Query: 280 TAKEFILWALTVSPKRRPTATDLINDIWI 308
+ + L ++P+RR + +++ D W+
Sbjct: 345 DCENLLKKFLVINPQRRSSLDNIMKDRWM 373
>CE23838 [R] KOG0586 Serine/threonine protein kinase
Length = 1192
Score = 149 bits (377), Expect = 6e-36
Identities = 89/269 (33%), Positives = 142/269 (52%), Gaps = 13/269 (4%)
Query: 41 VNKSDYIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQ 100
V+ Y KT+G G F V+ A+ + +G S LQ L+ E+ I++
Sbjct: 165 VHVGKYKLLKTIGKGNFAKVKLAKHVITGHEVAIKIIDKTALNPSS--LQKLFREVKIMK 222
Query: 101 QLNHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQY 160
QL+HPNIV+ E+++ Y+V + A+GGE+FD ++ G+ E +A +QI+ VQY
Sbjct: 223 QLDHPNIVKLYQVMETEQTLYLVLEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQY 282
Query: 161 LHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVL 220
LH +NI+HRDLK EN+L D + I DFG + N+L GS Y APE+
Sbjct: 283 LHSKNIIHRDLKAENLLL---DQDMNIKIADFGFSNTFSLGNKL-DTFCGSPPYAAPELF 338
Query: 221 TSSGH-GKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSK 279
+ + G D+WS+GVI YTL+ G PF ++ E G+Y + F+ +S
Sbjct: 339 SGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFY------MST 392
Query: 280 TAKEFILWALTVSPKRRPTATDLINDIWI 308
+ + L ++P+RR + +++ D W+
Sbjct: 393 DCENLLKKFLVINPQRRSSLDNIMKDRWM 421
>At5g35410 [T] KOG0583 Serine/threonine protein kinase
Length = 446
Score = 149 bits (377), Expect = 6e-36
Identities = 98/290 (33%), Positives = 145/290 (49%), Gaps = 19/290 (6%)
Query: 46 YIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNHP 105
Y G+T+G GTF V+ AR +G+N ++ + + E+SI++ + HP
Sbjct: 11 YEVGRTIGEGTFAKVKFARNTDTGDNVAIKIMAKSTIL-KNRMVDQIKREISIMKIVRHP 69
Query: 106 NIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRN 165
NIVR + S K YIV + TGGELFDRI+ KG+ E ++ +Q++ V + H +
Sbjct: 70 NIVRLYEVLASPSKIYIVLEFVTGGELFDRIVHKGRLEESESRKYFQQLVDAVAHCHCKG 129
Query: 166 IVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSGH 225
+ HRDLKPEN+L + L + DFG++ ++ EL+ G+ YVAPEVL+ G+
Sbjct: 130 VYHRDLKPENLLL---DTNGNLKVSDFGLSALPQEGVELLRTTCGTPNYVAPEVLSGQGY 186
Query: 226 -GKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKEF 284
G DIWS GVI + +L GY PF G + + + F P W S K
Sbjct: 187 DGSAADIWSCGVILFVILAGYLPFSETDLPGLYRKINAAE----FSCPPW--FSAEVKFL 240
Query: 285 ILWALTVSPKRRPTATDLINDIW-------ITSTEKSTTDLLPEIRKGFD 327
I L +PK R + D W I + E+ + L +IR FD
Sbjct: 241 IHRILDPNPKTRIQIQGIKKDPWFRLNYVPIRAREEEEVN-LDDIRAVFD 289
>SPCC18B5.11c [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 460
Score = 149 bits (375), Expect = 1e-35
Identities = 88/273 (32%), Positives = 143/273 (52%), Gaps = 14/273 (5%)
Query: 44 SDYIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXX---XXGQSVQLQMLYDELSILQ 100
S Y +TLG+GTF VV+ A ++SG+ + +M E+ IL+
Sbjct: 165 SHYEIIRTLGSGTFAVVKLAVEVNSGKWYAIKIINKRKILLTSSEKRATEMFQREIDILK 224
Query: 101 QLNHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQY 160
L+HP +V+ + FE+ ++ +IV + GG+L D ++ G E D ++KQ+L+ + +
Sbjct: 225 SLHHPGVVQCHEIFENDDELFIVMEYVEGGDLMDFLIANGSIDEQDCKPLLKQLLETLLH 284
Query: 161 LHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVL 220
LH++ + HRD+KPENIL N D L I DFG+AK + + G+MGY+APEVL
Sbjct: 285 LHKQGVTHRDIKPENILITN---DFHLKISDFGLAKVIHGTGTFLETFCGTMGYLAPEVL 341
Query: 221 TS------SGHGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYW 274
S G+ DIWS+G + Y +L PF + S IE + G YP+
Sbjct: 342 KSKNVNLDGGYDDKVDIWSLGCVLYVMLTASIPFASSSQAKCIELISKGAYPI--EPLLE 399
Query: 275 NNVSKTAKEFILWALTVSPKRRPTATDLINDIW 307
N +S+ + I L ++P++R + ++ + W
Sbjct: 400 NEISEEGIDLINRMLEINPEKRISESEALQHPW 432
>At1g74740 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 567
Score = 148 bits (374), Expect = 1e-35
Identities = 99/316 (31%), Positives = 157/316 (49%), Gaps = 16/316 (5%)
Query: 3 KKEPLSENNSRKPEEPEPVEGHKLTKLFNKVTGQPSSYVNK--SDYIFGKTLGAGTFGVV 60
KK+P ++P+ + H ++ P S+ ++ YI G+ LG G FG+
Sbjct: 20 KKKPPRGRQRNPYDDPDGLRTHAPLRVI------PMSHQSQISDKYILGRELGRGEFGIT 73
Query: 61 RQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQL-NHPNIVRFKDWFESKEK 119
+ E +V ++ + E++I+ L HPN+V+ K +E E
Sbjct: 74 YLCTDRETRE-ALACKSISKRKLRTAVDVEDVRREVTIMSTLPEHPNVVKLKATYEDNEN 132
Query: 120 FYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRNIVHRDLKPENILYL 179
++V +L GGELFDRI+ +G + E A + + I + V+ H ++HRDLKPEN L+
Sbjct: 133 VHLVMELCEGGELFDRIVARGHYTERAAATVARTIAEVVRMCHVNGVMHRDLKPENFLFA 192
Query: 180 NKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSGHGKPCDIWSIGVITY 239
NK ++S L DFG++ K E + GS Y+APEVL +G D+WS GVI Y
Sbjct: 193 NKKENSALKAIDFGLSVLFK-PGERFTEIVGSPYYMAPEVL-KRNYGPEVDVWSAGVILY 250
Query: 240 TLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKEFILWALTVSPKRRPTA 299
LLCG PF AE+ G G + F + W+ +S++AK + L +R TA
Sbjct: 251 ILLCGVPPFWAETEQGVALAILRG--VLDFKRDPWSQISESAKSLVKQMLEPDSTKRLTA 308
Query: 300 TDLI--NDIWITSTEK 313
++ N + ++ EK
Sbjct: 309 QQVLGNNAVLVSLMEK 324
>SPCC1322.08 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 580
Score = 148 bits (373), Expect = 2e-35
Identities = 80/262 (30%), Positives = 141/262 (53%), Gaps = 35/262 (13%)
Query: 85 QSVQLQMLYDELSILQQLNHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCE 144
Q V+ + E+ I++++ HPNI++ ++ ++ E +Y+V +LA GGELF +I+ F E
Sbjct: 171 QGVESHNILKEVQIMRRVKHPNIIQLLEFIQTPEYYYLVLELADGGELFHQIVRLTYFSE 230
Query: 145 VDAVFIVKQILQGVQYLHQR-NIVHRDLKPENILY------------------LNKSDDS 185
+ ++ Q+ ++YLH+ +VHRD+KPEN+L+ +K D+
Sbjct: 231 DLSRHVITQVAHAIRYLHEDCGVVHRDIKPENLLFDSIDFVPSRVRKYRAGDDPDKVDEG 290
Query: 186 PLVIG------------DFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSGHGKPCDIWS 233
+ G DFG++K + D + G+MGY APE++ + K D+W+
Sbjct: 291 EFIPGVGAGTIGRIRLADFGLSKVVWDSH--TQTPCGTMGYTAPEIVRDERYSKGVDMWA 348
Query: 234 IGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKEFILWALTVSP 293
+G + YT+LCG+ PF ES ++ + G+Y F P+W+++SK+AK+ I LTV P
Sbjct: 349 LGCVLYTILCGFPPFYDESISLLTKKVSRGEYS--FLSPWWDDISKSAKDLISHLLTVDP 406
Query: 294 KRRPTATDLINDIWITSTEKST 315
+ R + WI+ + + T
Sbjct: 407 ESRYDIHQFLAHPWISGSREPT 428
>Hs14777335 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 795
Score = 148 bits (373), Expect = 2e-35
Identities = 110/342 (32%), Positives = 172/342 (50%), Gaps = 27/342 (7%)
Query: 15 PEEPEPVEGHKLTKLFNKVTGQPSSYVNKSDYIFGKTLGAGTFGVVRQARCISSGENXXX 74
P P P E H++ + K T + Y + + LG G FG V + S+G
Sbjct: 467 PAPPAPFE-HRVVSV--KETSISAGY----EVCQHEVLGGGRFGQVHRCTEKSTGLPLAA 519
Query: 75 XXXXXXXXXGQSVQLQMLYDELSILQQLNHPNIVRFKDWFESKEKFYIVTQLATGGELFD 134
+ + + +E++I+ QL+H N+++ D FESK +V + GGELFD
Sbjct: 520 KIIKVKSAKDR----EDVKNEINIMNQLSHVNLIQLYDAFESKHSCTLVMEYVDGGELFD 575
Query: 135 RIL-EKGKFCEVDAVFIVKQILQGVQYLHQRNIVHRDLKPENILYLNKSDDSPLVIGDFG 193
RI EK E+D V +QI +GV YLHQ I+H DLKPENIL +N++ +I DFG
Sbjct: 576 RITDEKYHLTELDVVLFTRQICEGVHYLHQHYILHLDLKPENILCVNQTGHQIKII-DFG 634
Query: 194 IAKELKDDNELIHKAAGSMGYVAPEVLTSSGHGKPCDIWSIGVITYTLLCGYSPFLAES- 252
+A+ K E + G+ ++APEV+ P D+WS+GVITY LL G SPFL E+
Sbjct: 635 LARRYK-PREKLKVNFGTPEFLAPEVVNYEFVSFPTDMWSVGVITYMLLSGLSPFLGETD 693
Query: 253 --ADGFIEECTSGQYPVVFHKPYWNNVSKTAKEFILWALTVSPKRRPTATDLINDIWITS 310
FI C+ F + +S+ AK+F+ L R +AT + W+ +
Sbjct: 694 AETMNFIVNCSWD-----FDADTFEGLSEEAKDFVSRLLVKEKSCRMSATQCLKHEWLNN 748
Query: 311 ----TEKSTTDLLPE-IRKGFDARKEFRDAVEIVKLNNRIKK 347
+S T L + + + + A+++++ +V NR++K
Sbjct: 749 LPAKASRSKTRLKSQLLLQKYIAQRKWKKHFYVVTAANRLRK 790
>Hs10863901 [T] KOG0604 MAP kinase-activated protein kinase 2
Length = 370
Score = 148 bits (373), Expect = 2e-35
Identities = 90/219 (41%), Positives = 120/219 (54%), Gaps = 13/219 (5%)
Query: 105 PNIVRFKDWFES----KEKFYIVTQLATGGELFDRILEKGK--FCEVDAVFIVKQILQGV 158
P+IVR D +E+ ++ IV + GGELF RI ++G F E +A I+K I + +
Sbjct: 115 PHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAI 174
Query: 159 QYLHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPE 218
QYLH NI HRD+KPEN+LY +K ++ L + DFG AKE N L + YVAPE
Sbjct: 175 QYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLT-TPCYTPYYVAPE 233
Query: 219 VLTSSGHGKPCDIWSIGVITYTLLCGYSPFLAES----ADGFIEECTSGQYPVVFHKPYW 274
VL + K CD+WS+GVI Y LLCGY PF + + G GQY F P W
Sbjct: 234 VLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYE--FPNPEW 291
Query: 275 NNVSKTAKEFILWALTVSPKRRPTATDLINDIWITSTEK 313
+ VS+ K I L P +R T T+ +N WI + K
Sbjct: 292 SEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTK 330
>At2g35890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 520
Score = 147 bits (371), Expect = 3e-35
Identities = 94/267 (35%), Positives = 135/267 (50%), Gaps = 6/267 (2%)
Query: 43 KSDYIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQL 102
K Y G LG G FG +GE + ++ + E+ I++ L
Sbjct: 129 KEYYNLGSKLGHGQFGTTFVCVEKGTGEEYACKSIPKRKLENEE-DVEDVRREIEIMKHL 187
Query: 103 -NHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYL 161
PN++ K +E ++V +L GGELFDRI+E+G + E A + K IL VQ
Sbjct: 188 LGQPNVISIKGAYEDSVAVHMVMELCRGGELFDRIVERGHYSERKAAHLAKVILGVVQTC 247
Query: 162 HQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLT 221
H ++HRDLKPEN L++N +DSPL DFG++ LK E GS Y+APEVL
Sbjct: 248 HSLGVMHRDLKPENFLFVNDDEDSPLKAIDFGLSMFLK-PGENFTDVVGSPYYIAPEVL- 305
Query: 222 SSGHGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTA 281
+ +G DIWS GV+ Y LL G +PF E+ + E G+ + W VS++A
Sbjct: 306 NKNYGPEADIWSAGVMIYVLLSGSAPFWGETEEEIFNEVLEGELDLT--SDPWPQVSESA 363
Query: 282 KEFILWALTVSPKRRPTATDLINDIWI 308
K+ I L +P +R TA ++ WI
Sbjct: 364 KDLIRKMLERNPIQRLTAQQVLCHPWI 390
>SPAC14C4.03 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 445
Score = 147 bits (370), Expect = 4e-35
Identities = 88/236 (37%), Positives = 132/236 (55%), Gaps = 22/236 (9%)
Query: 95 ELSILQQLNHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQI 154
E++IL++L+HPNI++ + S+ +F+I ++ TGG+LF + + G EV +FI+ QI
Sbjct: 206 EMTILRKLDHPNIIKVNMEYNSETQFFIFEEMVTGGDLFSYLTKLGTVPEVTTLFIMFQI 265
Query: 155 LQGVQYLHQRNIVHRDLKPENILYLNKSDD-SPLVIGDFGIAKELKDDNELIHKAAGSMG 213
LQG++YLH++NI+HRDLK ENIL + SD +++ DFG+A+ ++ L G+
Sbjct: 266 LQGLKYLHEQNIIHRDLKLENILIASSSDTIFRIILTDFGVARCMQKGKRL-STFVGTPE 324
Query: 214 YVAPEVL-----------TSSGHGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTS 262
Y APE+ SSG+GK D+WS+GVI + LL G SP ADG E+
Sbjct: 325 YTAPEIQRLKGRSQVEKENSSGYGKEVDLWSLGVIMFLLLSGNSP---SFADGVKEK--- 378
Query: 263 GQYPVVFHKPYWNNVSKTAKEFILWALTVSPKRRPTATDLINDIWITSTEKSTTDL 318
V F P W +VS+ AK+ I L +P R T ++ W T L
Sbjct: 379 ---QVDFRDPVWKSVSRQAKDLISNLLKTNPPDRFTVKQCLSHPWFARHSSRLTKL 431
>At3g29160 [T] KOG0583 Serine/threonine protein kinase
Length = 512
Score = 147 bits (370), Expect = 4e-35
Identities = 88/264 (33%), Positives = 138/264 (51%), Gaps = 12/264 (4%)
Query: 45 DYIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNH 104
+Y GKTLG G+FG V+ A + +G ++ + + E+ IL+ H
Sbjct: 19 NYKLGKTLGIGSFGKVKIAEHVVTGHKVAIKILNRRKIKNMEME-EKVRREIKILRLFMH 77
Query: 105 PNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQR 164
P+I+R + E+ Y+V + GELFD I+EKG+ E +A +QI+ GV+Y H+
Sbjct: 78 PHIIRQYEVIETTSDIYVVMEYVKSGELFDYIVEKGRLQEDEARNFFQQIISGVEYCHRN 137
Query: 165 NIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSG 224
+VHRDLKPEN+L ++ + + I DFG++ ++ D + + GS Y APEV++
Sbjct: 138 MVVHRDLKPENLLLDSRCN---IKIADFGLSNVMR-DGHFLKTSCGSPNYAAPEVISGKL 193
Query: 225 HGKP-CDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKE 283
+ P D+WS GVI Y LLCG PF E+ ++ G Y + H +S A++
Sbjct: 194 YAGPEVDVWSCGVILYALLCGTLPFDDENIPNLFKKIKGGIYTLPSH------LSSEARD 247
Query: 284 FILWALTVSPKRRPTATDLINDIW 307
I L V P +R T ++ W
Sbjct: 248 LIPRMLIVDPVKRITIPEIRQHRW 271
>At2g30360 [T] KOG0583 Serine/threonine protein kinase
Length = 435
Score = 147 bits (370), Expect = 4e-35
Identities = 91/310 (29%), Positives = 152/310 (48%), Gaps = 27/310 (8%)
Query: 46 YIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNHP 105
Y GK LG G F V AR +G++ + E+SI+++L+HP
Sbjct: 21 YELGKLLGCGAFAKVFHARDRRTGQSVAVKILNKKKLLTNPALANNIKREISIMRRLSHP 80
Query: 106 NIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRN 165
NIV+ + +K K + + GGELF++I + G+ E + +Q++ V Y H R
Sbjct: 81 NIVKLHEVMATKSKIFFAMEFVKGGELFNKISKHGRLSEDLSRRYFQQLISAVGYCHARG 140
Query: 166 IVHRDLKPENILYLNKSDDSPLVIGDFGIA---KELKDDNELIHKAAGSMGYVAPEVLTS 222
+ HRDLKPEN+L ++ L + DFG++ +++ D L+H G+ YVAPE+L+
Sbjct: 141 VYHRDLKPENLLI---DENGNLKVSDFGLSALTDQIRPDG-LLHTLCGTPAYVAPEILSK 196
Query: 223 SGH-GKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTA 281
G+ G D+WS G++ + L+ GY PF + ++ G+Y P W +S
Sbjct: 197 KGYEGAKVDVWSCGIVLFVLVAGYLPFNDPNVMNMYKKIYKGEY----RFPRW--MSPDL 250
Query: 282 KEFILWALTVSPKRRPTATDLINDIWITSTEKSTTDLLPEIRKGFDARKEFRDAVEIVKL 341
K F+ L ++P+ R T +++ D W +R GF K D +E K+
Sbjct: 251 KRFVSRLLDINPETRITIDEILKDPWF-------------VRGGFKQIKFHDDEIEDQKV 297
Query: 342 NNRIKKLKVL 351
+ ++ +K L
Sbjct: 298 ESSLEAVKSL 307
>Hs4759052 [T] KOG0603 Ribosomal protein S6 kinase
Length = 809
Score = 146 bits (369), Expect = 5e-35
Identities = 83/266 (31%), Positives = 140/266 (52%), Gaps = 15/266 (5%)
Query: 50 KTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNHPNIVR 109
K LG G+F + R +C+ N + Q ++ +L HPNIV+
Sbjct: 430 KPLGEGSFSICR--KCVHKKSNQALQVKIISKRMEANTQKEITALKLCE----GHPNIVK 483
Query: 110 FKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRNIVHR 169
+ F + ++V +L GGELFD + +K F E +A +I+++++ + ++H +VHR
Sbjct: 484 LHEVFHDQLHTFLVMELLNGGELFDALRKKKHFSETEASYIMRKLVSALSHMHDLGVVHR 543
Query: 170 DLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSGHGKPC 229
DLKPEN+L+ +++D+ + I DFG A+ DN+ + ++ PE+L +G+ + C
Sbjct: 544 DLKPENLLFTDENDNLEIKIIDFGFARLKPPDNQPLKTPCFTLHSCRPELLNQNGYDESC 603
Query: 230 DIWSIGVITYTLLCGYSPFLAE-------SADGFIEECTSGQYPVVFHKPYWNNVSKTAK 282
D+WS+GVI YT+L G PF + SA +++ G + F W NVS+ AK
Sbjct: 604 DLWSLGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFS--FEGEAWKNVSQEAK 661
Query: 283 EFILWALTVSPKRRPTATDLINDIWI 308
+ I LTV P +R + L + W+
Sbjct: 662 DLIQGLLTVDPNKRLKMSGLRYNEWL 687
Score = 110 bits (274), Expect = 5e-24
Identities = 73/254 (28%), Positives = 126/254 (48%), Gaps = 12/254 (4%)
Query: 50 KTLGAGTFGVVRQARCIS---SGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNH-P 105
K LG G +G V R IS +G+ ++ + E +L+ + P
Sbjct: 53 KVLGTGAYGKVFLVRKISGHDTGKLYAMKVLKKATIVQKAKTTEHTRTERQVLEHIRQSP 112
Query: 106 NIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRN 165
+V F+++ K +++ GGELF + ++ +F E + V +I+ +++LH+
Sbjct: 113 FLVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLALEHLHKLG 172
Query: 166 IVHRDLKPENILYLNKSDDSPLVIGDFGIAKE-LKDDNELIHKAAGSMGYVAPEVLT--S 222
I++RD+K ENIL + +V+ DFG++KE + D+ E + G++ Y+AP+++
Sbjct: 173 IIYRDIKLENILL---DSNGHVVLTDFGLSKEFVADETERAYSFCGTIEYMAPDIVRGGD 229
Query: 223 SGHGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAK 282
SGH K D WS+GV+ Y LL G SPF + + + + PY +S AK
Sbjct: 230 SGHDKAVDWWSLGVLMYELLTGASPFTVDGEKN--SQAEISRRILKSEPPYPQEMSALAK 287
Query: 283 EFILWALTVSPKRR 296
+ I L PK+R
Sbjct: 288 DLIQRLLMKDPKKR 301
>At5g24430 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 594
Score = 146 bits (369), Expect = 5e-35
Identities = 92/267 (34%), Positives = 143/267 (53%), Gaps = 8/267 (2%)
Query: 46 YIFGKTLGAGTFGVVRQARCISSG--ENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLN 103
Y GK +G G FG A+ ++ ++ + E+ +L+ L+
Sbjct: 143 YELGKEVGRGHFGHTCWAKAKKGKMKNQTVAVKIISKAKMTSTLSIEDVRREVKLLKALS 202
Query: 104 -HPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKG-KFCEVDAVFIVKQILQGVQYL 161
H ++V+F D +E + ++V +L GGEL DRIL +G ++ EVDA I+ QIL +
Sbjct: 203 GHRHMVKFYDVYEDADNVFVVMELCEGGELLDRILARGGRYPEVDAKRILVQILSATAFF 262
Query: 162 HQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLT 221
H + +VHRDLKPEN L+ ++++D+ L + DFG++ ++ D L + GS YVAPEVL
Sbjct: 263 HLQGVVHRDLKPENFLFTSRNEDAILKVIDFGLSDFIRYDQRL-NDVVGSAYYVAPEVLH 321
Query: 222 SSGHGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTA 281
S + D+WSIGVI+Y LLCG PF + + I C P P W ++S TA
Sbjct: 322 RS-YSTEADMWSIGVISYILLCGSRPFYGRT-ESAIFRCVLRANPNFEDMP-WPSISPTA 378
Query: 282 KEFILWALTVSPKRRPTATDLINDIWI 308
K+F+ L ++R TA + W+
Sbjct: 379 KDFVKRLLNKDHRKRMTAAQALAHPWL 405
>At3g17510 [T] KOG0583 Serine/threonine protein kinase
Length = 446
Score = 146 bits (369), Expect = 5e-35
Identities = 96/266 (36%), Positives = 134/266 (50%), Gaps = 15/266 (5%)
Query: 46 YIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNHP 105
Y G+TLG G FG V+ A+ SG + + LQ + E+ L+ L HP
Sbjct: 20 YELGRTLGEGNFGKVKFAKDTVSGHSFAVKIIDKSRIADLNFSLQ-IKREIRTLKMLKHP 78
Query: 106 NIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRN 165
+IVR + SK K +V +L TGGELFDRI+ GK E D + +Q++ G+ Y H +
Sbjct: 79 HIVRLHEVLASKTKINMVMELVTGGELFDRIVSNGKLTETDGRKMFQQLIDGISYCHSKG 138
Query: 166 IVHRDLKPENILYLNKSDDSPLVIGDFGIA---KELKDDNELIHKAAGSMGYVAPEVLTS 222
+ HRDLK EN+L K + I DFG++ + +DD L+H GS YVAPEVL +
Sbjct: 139 VFHRDLKLENVLLDAKGH---IKITDFGLSALPQHFRDDG-LLHTTCGSPNYVAPEVLAN 194
Query: 223 SGH-GKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTA 281
G+ G DIWS GVI Y +L G PF + ++ G P+ P W +S A
Sbjct: 195 RGYDGAASDIWSCGVILYVILTGCLPFDDRNLAVLYQKICKGDPPI----PRW--LSPGA 248
Query: 282 KEFILWALTVSPKRRPTATDLINDIW 307
+ I L +P R T + W
Sbjct: 249 RTMIKRMLDPNPVTRITVVGIKASEW 274
>Hs9845489 [R] KOG0586 Serine/threonine protein kinase
Length = 691
Score = 146 bits (368), Expect = 7e-35
Identities = 91/265 (34%), Positives = 139/265 (52%), Gaps = 13/265 (4%)
Query: 45 DYIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNH 104
+Y KT+G G F V+ AR I +G+ S LQ L+ E+ I++ LNH
Sbjct: 19 NYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSS--LQKLFREVRIMKVLNH 76
Query: 105 PNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQR 164
PNIV+ + E+++ Y+V + A+GGE+FD ++ G+ E +A +QI+ VQY HQ+
Sbjct: 77 PNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQK 136
Query: 165 NIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSG 224
IVHRDLK EN+L D + I DFG + E N+L GS Y APE+
Sbjct: 137 FIVHRDLKAENLLL---DADMNIKIADFGFSNEFTFGNKL-DTFCGSPPYAAPELFQGKK 192
Query: 225 H-GKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKE 283
+ G D+WS+GVI YTL+ G PF ++ E G+Y + F+ +S +
Sbjct: 193 YDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFY------MSTDCEN 246
Query: 284 FILWALTVSPKRRPTATDLINDIWI 308
+ L ++P +R T ++ D W+
Sbjct: 247 LLKKFLILNPSKRGTLEQIMKDRWM 271
>Hs9845487 [R] KOG0586 Serine/threonine protein kinase
Length = 745
Score = 146 bits (368), Expect = 7e-35
Identities = 91/265 (34%), Positives = 139/265 (52%), Gaps = 13/265 (4%)
Query: 45 DYIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNH 104
+Y KT+G G F V+ AR I +G+ S LQ L+ E+ I++ LNH
Sbjct: 19 NYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSS--LQKLFREVRIMKVLNH 76
Query: 105 PNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQR 164
PNIV+ + E+++ Y+V + A+GGE+FD ++ G+ E +A +QI+ VQY HQ+
Sbjct: 77 PNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQK 136
Query: 165 NIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSG 224
IVHRDLK EN+L D + I DFG + E N+L GS Y APE+
Sbjct: 137 FIVHRDLKAENLLL---DADMNIKIADFGFSNEFTFGNKL-DTFCGSPPYAAPELFQGKK 192
Query: 225 H-GKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKE 283
+ G D+WS+GVI YTL+ G PF ++ E G+Y + F+ +S +
Sbjct: 193 YDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFY------MSTDCEN 246
Query: 284 FILWALTVSPKRRPTATDLINDIWI 308
+ L ++P +R T ++ D W+
Sbjct: 247 LLKKFLILNPSKRGTLEQIMKDRWM 271
>Hs8923922 [R] KOG0586 Serine/threonine protein kinase
Length = 795
Score = 146 bits (368), Expect = 7e-35
Identities = 91/279 (32%), Positives = 142/279 (50%), Gaps = 13/279 (4%)
Query: 31 NKVTGQPSSYVNKSDYIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQ 90
N +T + +Y KT+G G F V+ AR + +G S LQ
Sbjct: 45 NSITSATDEQPHIGNYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTS--LQ 102
Query: 91 MLYDELSILQQLNHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFI 150
L+ E+ I++ LNHPNIV+ + E+++ Y+V + A+GGE+FD ++ G+ E +A
Sbjct: 103 KLFREVRIMKILNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAK 162
Query: 151 VKQILQGVQYLHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAG 210
+QI+ VQY HQ+ IVHRDLK EN+L D + I DFG + E N+L G
Sbjct: 163 FRQIVSAVQYCHQKYIVHRDLKAENLLL---DGDMNIKIADFGFSNEFTVGNKL-DTFCG 218
Query: 211 SMGYVAPEVLTSSGH-GKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVF 269
S Y APE+ + G D+WS+GVI YTL+ G PF ++ E G+Y + F
Sbjct: 219 SPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPF 278
Query: 270 HKPYWNNVSKTAKEFILWALTVSPKRRPTATDLINDIWI 308
+ +S + + L ++P +R + ++ D W+
Sbjct: 279 Y------MSTDCENLLKKLLVLNPIKRGSLEQIMKDRWM 311
>At4g35310 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 556
Score = 146 bits (368), Expect = 7e-35
Identities = 102/312 (32%), Positives = 148/312 (46%), Gaps = 11/312 (3%)
Query: 2 FKKEPLSENNSRKPEEP----EPVEGHKLTKLFNKVTGQPSSYVNKSDYIFGKTLGAGTF 57
F K+ S NNS+ P EP+ V G + + + Y + LG G F
Sbjct: 50 FSKDNNSNNNSKDPALVIPLREPIMRRNPDNQAYYVLGHKTPNI-RDIYTLSRKLGQGQF 108
Query: 58 GVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQL-NHPNIVRFKDWFES 116
G I+SG + + ++ + E+ I+ L H +IV K +E
Sbjct: 109 GTTYLCTEIASGVDYACKSISKRKLISKE-DVEDVRREIQIMHHLAGHGSIVTIKGAYED 167
Query: 117 KEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRNIVHRDLKPENI 176
+IV +L GGELFDRI+++G + E A + K I+ V+ H ++HRDLKPEN
Sbjct: 168 SLYVHIVMELCAGGELFDRIIQRGHYSERKAAELTKIIVGVVEACHSLGVMHRDLKPENF 227
Query: 177 LYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSGHGKPCDIWSIGV 236
L +NK DD L DFG++ K ++ GS YVAPEVL +G D+W+ GV
Sbjct: 228 LLVNKDDDFSLKAIDFGLSVFFK-PGQIFTDVVGSPYYVAPEVLLKR-YGPEADVWTAGV 285
Query: 237 ITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKEFILWALTVSPKRR 296
I Y LL G PF AE+ G + G + F W +S +AK+ I L+ P R
Sbjct: 286 ILYILLSGVPPFWAETQQGIFDAVLKGY--IDFESDPWPVISDSAKDLIRRMLSSKPAER 343
Query: 297 PTATDLINDIWI 308
TA +++ WI
Sbjct: 344 LTAHEVLRHPWI 355
>7298652 [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 459
Score = 145 bits (367), Expect = 9e-35
Identities = 88/286 (30%), Positives = 145/286 (49%), Gaps = 13/286 (4%)
Query: 31 NKVTGQPSSYVNKSDYIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQ 90
N+ G P +NK+ Y+ + LG+G +G+VR + + G
Sbjct: 144 NESIGLPEE-INKTYYV-NRKLGSGAYGLVRLVYDTRTCQQFAMKIVKKNMLSGARPSTN 201
Query: 91 M-----LYDELSILQQLNHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEV 145
+ +E I++ L+HP +VR D + + Y+V + GG+L +RI+ E
Sbjct: 202 FSDPDRVLNEAKIMKNLSHPCVVRMHDIVDKPDSVYMVLEFMRGGDLLNRIISNKLLSED 261
Query: 146 DAVFIVKQILQGVQYLHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELI 205
+ Q+ V+YLH R I HRDLKP+N+L +++ L + DFG++K ++ D+ ++
Sbjct: 262 ISKLYFYQMCHAVKYLHDRGITHRDLKPDNVLLETNDEETLLKVSDFGLSKFVQKDS-VM 320
Query: 206 HKAAGSMGYVAPEVLTSSG---HGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTS 262
G+ YVAPEVL + G + K DIWS+GV+ +T L G PF E ++
Sbjct: 321 RTLCGTPLYVAPEVLITGGREAYTKKVDIWSLGVVLFTCLSGTLPFSDEYGTPAAQQIKK 380
Query: 263 GQYPVVFHKPYWNNVSKTAKEFILWALTVSPKRRPTATDLINDIWI 308
G++ + P W +VS+ AK I L V P+RRP+ D++ W+
Sbjct: 381 GRF--AYGHPSWKSVSQRAKLLINQMLIVDPERRPSIDDVLQSSWL 424
>7290629 [T] KOG0604 MAP kinase-activated protein kinase 2
Length = 359
Score = 145 bits (367), Expect = 9e-35
Identities = 96/280 (34%), Positives = 136/280 (48%), Gaps = 14/280 (5%)
Query: 36 QPSSYVNKSDYIFGKT-LGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYD 94
QP + DY+ T LG G G V Q + +N + V L
Sbjct: 9 QPKTTPLTDDYVTSNTVLGYGINGKVVQCTHRRTQQNYALKVLLDSERARREVDLHWRVS 68
Query: 95 ELSILQQLNHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEK--GKFCEVDAVFIVK 152
+ + I +++ F+ ++ +V + GGELF RI +K G F E +A I+
Sbjct: 69 GCRYIVNI----IDVYENTFKDRKCLLVVMECMEGGELFQRIQDKADGAFTEREAAQIMH 124
Query: 153 QILQGVQYLHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSM 212
+I V YLH R+I HRDLKPEN+LY ++ L + DFG AKE L +
Sbjct: 125 EICAAVDYLHSRDIAHRDLKPENLLYTTTQPNATLKLTDFGFAKETFTSYTL-QTPCYTP 183
Query: 213 GYVAPEVLTSSGHGKPCDIWSIGVITYTLLCGYSPFLAES----ADGFIEECTSGQYPVV 268
YVAPEVL + K CDIWS+GV+ Y ++CG+ PF + + G +GQY
Sbjct: 184 YYVAPEVLGPEKYDKSCDIWSLGVVMYIIMCGFPPFYSNHGLAISPGMKNRIRTGQYD-- 241
Query: 269 FHKPYWNNVSKTAKEFILWALTVSPKRRPTATDLINDIWI 308
F P W NVS+ AK+ I L V P +R D+I++ WI
Sbjct: 242 FPDPEWTNVSQAAKDLIKGMLNVDPSKRLRIQDVISNKWI 281
>At3g01090 [T] KOG0583 Serine/threonine protein kinase
Length = 512
Score = 145 bits (366), Expect = 1e-34
Identities = 88/264 (33%), Positives = 137/264 (51%), Gaps = 12/264 (4%)
Query: 45 DYIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNH 104
+Y G+TLG G+FG V+ A +G ++ + + E+ IL+ H
Sbjct: 18 NYKLGRTLGIGSFGRVKIAEHALTGHKVAIKILNRRKIKNMEME-EKVRREIKILRLFMH 76
Query: 105 PNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQR 164
P+I+R + E+ Y+V + GELFD I+EKG+ E +A +QI+ GV+Y H+
Sbjct: 77 PHIIRLYEVIETPTDIYLVMEYVNSGELFDYIVEKGRLQEDEARNFFQQIISGVEYCHRN 136
Query: 165 NIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSG 224
+VHRDLKPEN+L +K + + I DFG++ ++ D + + GS Y APEV++
Sbjct: 137 MVVHRDLKPENLLLDSKCN---VKIADFGLSNIMR-DGHFLKTSCGSPNYAAPEVISGKL 192
Query: 225 HGKP-CDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKE 283
+ P D+WS GVI Y LLCG PF E+ ++ G Y + H +S A++
Sbjct: 193 YAGPEVDVWSCGVILYALLCGTLPFDDENIPNLFKKIKGGIYTLPSH------LSPGARD 246
Query: 284 FILWALTVSPKRRPTATDLINDIW 307
I L V P +R T ++ W
Sbjct: 247 LIPRMLVVDPMKRVTIPEIRQHPW 270
>CE18058_1 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 416
Score = 145 bits (366), Expect = 1e-34
Identities = 95/295 (32%), Positives = 150/295 (50%), Gaps = 15/295 (5%)
Query: 55 GTFGVVRQARCISSGENXXXXXXXXX--XXXGQSVQLQMLYDELSILQQLN-HPNIVRFK 111
G F VVR+ R +GE + V Q + E+ +LQ++ + N+V
Sbjct: 80 GQFAVVRRVRDRKTGEKYAAKFIKKRRYATSRRGVTRQNIEREVRVLQKIRGNSNVVELH 139
Query: 112 DWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRNIVHRDL 171
+E+ IV +L +GGELFD + K EV+A +KQIL V++LH +IVH D+
Sbjct: 140 AVYETASDVIIVLELVSGGELFDHVCAKECLDEVEAAAFIKQILLAVRHLHSLHIVHLDI 199
Query: 172 KPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSGHGKPCDI 231
KPEN++ L + DS + I DFG+++E+ + ++ G+ +VAPEV+ D+
Sbjct: 200 KPENVM-LKQRGDSQIKIIDFGLSREI-EPGAVVKDMVGTPEFVAPEVVNYEALSPATDM 257
Query: 232 WSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKEFILWALTV 291
W++GV+TY LL G SPFL ++ D T +Y F Y+ N SK AK+FI
Sbjct: 258 WAVGVVTYILLSGGSPFLGDNRDETFSNITRVRYH--FSDRYFKNTSKHAKDFIYRLFVR 315
Query: 292 SPKRRPTATDLINDIWITSTEKSTTDL-------LPEIRKGFDARKEFRDAVEIV 339
+R T + + WI E + D+ + I + F R+ ++ VE+V
Sbjct: 316 DVDQRATVEECLQHPWIRGPEGNAIDIRKASCITISHI-QSFKTRQRWKRCVELV 369
>CE09360 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 2783
Score = 145 bits (365), Expect = 1e-34
Identities = 93/310 (30%), Positives = 159/310 (51%), Gaps = 24/310 (7%)
Query: 14 KPEEPEPVEGHKLTKLFNKVTGQPSSYVN----------KSDYIFGKTLGAGTFGVVRQA 63
K +E E V+ ++ K +PS Y ++ YI + LG G +G V +A
Sbjct: 158 KVKEQESVDYERVAK-----DSEPSEYKTIDIHRLPNDLQAKYIIHEELGKGAYGTVYRA 212
Query: 64 RCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNHPNIVRFKDWFESKEKFYIV 123
++G+ V+ + + E+S++ QL+H ++ + F+ + +++
Sbjct: 213 TEKATGKTWAAKMVQVR----PGVKKENVIHEISMMNQLHHEKLLNLHEAFDMGNEMWLI 268
Query: 124 TQLATGGELFDRILEKGKFCEVDAVF-IVKQILQGVQYLHQRNIVHRDLKPENILYLNKS 182
+ +GGELF++ILE + V + QIL GV ++H+ IVH DLKPENIL L
Sbjct: 269 EEFVSGGELFEKILEDDSLMSEEEVRDYMHQILLGVSHMHKNQIVHLDLKPENIL-LKAK 327
Query: 183 DDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSGHGKPCDIWSIGVITYTLL 242
+ + L I DFG+A++L D + + G+ + APEV+ G D+W++GVI+Y LL
Sbjct: 328 NSNELKIIDFGLARKL-DPKKSVKLLFGTPEFCAPEVVNYQPVGLSTDMWTVGVISYVLL 386
Query: 243 CGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKEFILWALTVSPKRRPTATDL 302
G SPFL +S + + ++ + F P W++VS AK+FI + ++R + D
Sbjct: 387 SGLSPFLGDSDEDTLANVSASDWD--FDDPSWDDVSDLAKDFICRLMIKDKRKRMSVQDA 444
Query: 303 INDIWITSTE 312
+ WIT +
Sbjct: 445 LRHPWITKMQ 454
>At1g12680 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 470
Score = 145 bits (365), Expect = 1e-34
Identities = 95/331 (28%), Positives = 160/331 (47%), Gaps = 21/331 (6%)
Query: 45 DYIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLN- 103
DY+FG+ +G G FG VR + +G + ++ E+ I+Q L+
Sbjct: 106 DYVFGRNIGKGKFGSVRICKSRKNGTEFACKTLKKGE--------ETVHREVEIMQHLSG 157
Query: 104 HPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQ 163
HP +V +E + F++V +L +GG L D++++ G++ E A I K ++ + Y H+
Sbjct: 158 HPRVVTLHAVYEESDCFHLVMELCSGGRLIDQMVKVGRYSEQRAANIFKDLMLVINYCHE 217
Query: 164 RNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSS 223
+VHRD+KPENIL + + + DFG+A + + + AGS YVAPEVL S
Sbjct: 218 MGVVHRDIKPENILL---TAAGKIQLADFGLAMRIA-KGQTLSGLAGSPAYVAPEVL-SE 272
Query: 224 GHGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKE 283
+ + D+WS GV+ Y LL G PF +S D E + + F+ W +VSK A++
Sbjct: 273 NYSEKVDVWSAGVLLYALLSGVLPFKGDSLDAIFEAIKN--VKLDFNTGVWESVSKPARD 330
Query: 284 FILWALTVSPKRRPTATDLINDIWITSTEKSTTDLL-----PEIRKGFDARKEFRDAVEI 338
+ LT R TA +++ WI T + + + G + R E
Sbjct: 331 LLARMLTREESARITADEVLRHPWILFYTDRTLKTMCIKSKHKSQAGSSTCLQNRSPTEK 390
Query: 339 VKLNNRIKKLKVLYENQDESDTDIEVNSTDS 369
LN ++ K+ ++ +S ++ E +S
Sbjct: 391 TDLNRADREKKIPSDSPTDSFSNTEEEEDES 421
>At4g38230 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 484
Score = 144 bits (363), Expect = 3e-34
Identities = 91/264 (34%), Positives = 130/264 (48%), Gaps = 6/264 (2%)
Query: 46 YIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQL-NH 104
Y G LG G FG + IS+G + ++ + E+ I+ L +
Sbjct: 24 YSLGHKLGQGQFGTTYMCKEISTGREYACKSITKRKLISKE-DVEDVRREIQIMHHLAGY 82
Query: 105 PNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQR 164
NIV K +E +IV +L +GGELFDRI+++G + E A ++K I+ V+ H
Sbjct: 83 KNIVTIKGAYEDPLYVHIVMELCSGGELFDRIIQRGHYSERKAAELIKIIVGVVEACHSL 142
Query: 165 NIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSG 224
++HRDLKPEN L +NK DD L DFG++ K ++ GS YVAPEVL
Sbjct: 143 GVMHRDLKPENFLLVNKDDDFSLKAIDFGLSVFFK-PGQIFEDVVGSPYYVAPEVLLKH- 200
Query: 225 HGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKEF 284
+G D+W+ GVI Y L+ G PF AE+ G + G + F W +S +AK
Sbjct: 201 YGPEADVWTAGVILYILVSGVPPFWAETQQGIFDAVLKGH--IDFDSDPWPLISDSAKNL 258
Query: 285 ILWALTVSPKRRPTATDLINDIWI 308
I L P R TA ++ WI
Sbjct: 259 IRGMLCSRPSERLTAHQVLRHPWI 282
>CE27583 [T] KOG0604 MAP kinase-activated protein kinase 2
Length = 425
Score = 144 bits (362), Expect = 3e-34
Identities = 96/282 (34%), Positives = 142/282 (50%), Gaps = 22/282 (7%)
Query: 40 YVNKSDY-IFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSI 98
Y DY I K LG G G V + SG+ + V+L ++
Sbjct: 65 YPVTQDYRISRKVLGVGINGKVVECEHRQSGDKFALKVLRDTQKARREVELHVMAS---- 120
Query: 99 LQQLNHPNIVR----FKDWFESKEKFYIVTQLATGGELFDRILEKGK--FCEVDAVFIVK 152
H ++V +K+ + + +V + GGELF+RI E+G+ F E +A IV
Sbjct: 121 ----GHGHVVSVHDVYKNSYNGVDCLLVVMENMKGGELFNRIQERGQKAFTEREAAGIVN 176
Query: 153 QILQGVQYLHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKEL-KDDNELIHKAAGS 211
+I V +LH+ +I HRDLKPEN+LY+ + ++ L + DFG AK+ + + + + A +
Sbjct: 177 EICSAVAHLHRMSIAHRDLKPENLLYVTTASNAALKLTDFGFAKKTDESEPQGLKTACFT 236
Query: 212 MGYVAPEVLTSSGHGKPCDIWSIGVITYTLLCGYSPFLAE----SADGFIEECTSGQYPV 267
Y APEVL + + K CD+WSIGVI Y LLCGY PF ++ + G + SGQY
Sbjct: 237 PYYCAPEVLGTEKYDKSCDLWSIGVIMYILLCGYPPFYSQHGQPMSPGMKAKIKSGQY-- 294
Query: 268 VFHKPYWNNVSKTAKEFILWALTVSPKRRPTATDLINDIWIT 309
F P W+ VS+ AK+ I L P R T + WI+
Sbjct: 295 TFPSPEWDCVSEAAKDLIRKLLRTEPTERITIEQTMEHKWIS 336
>CE17545 [T] KOG0604 MAP kinase-activated protein kinase 2
Length = 443
Score = 144 bits (362), Expect = 3e-34
Identities = 96/282 (34%), Positives = 142/282 (50%), Gaps = 22/282 (7%)
Query: 40 YVNKSDY-IFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSI 98
Y DY I K LG G G V + SG+ + V+L ++
Sbjct: 83 YPVTQDYRISRKVLGVGINGKVVECEHRQSGDKFALKVLRDTQKARREVELHVMAS---- 138
Query: 99 LQQLNHPNIVR----FKDWFESKEKFYIVTQLATGGELFDRILEKGK--FCEVDAVFIVK 152
H ++V +K+ + + +V + GGELF+RI E+G+ F E +A IV
Sbjct: 139 ----GHGHVVSVHDVYKNSYNGVDCLLVVMENMKGGELFNRIQERGQKAFTEREAAGIVN 194
Query: 153 QILQGVQYLHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKEL-KDDNELIHKAAGS 211
+I V +LH+ +I HRDLKPEN+LY+ + ++ L + DFG AK+ + + + + A +
Sbjct: 195 EICSAVAHLHRMSIAHRDLKPENLLYVTTASNAALKLTDFGFAKKTDESEPQGLKTACFT 254
Query: 212 MGYVAPEVLTSSGHGKPCDIWSIGVITYTLLCGYSPFLAE----SADGFIEECTSGQYPV 267
Y APEVL + + K CD+WSIGVI Y LLCGY PF ++ + G + SGQY
Sbjct: 255 PYYCAPEVLGTEKYDKSCDLWSIGVIMYILLCGYPPFYSQHGQPMSPGMKAKIKSGQY-- 312
Query: 268 VFHKPYWNNVSKTAKEFILWALTVSPKRRPTATDLINDIWIT 309
F P W+ VS+ AK+ I L P R T + WI+
Sbjct: 313 TFPSPEWDCVSEAAKDLIRKLLRTEPTERITIEQTMEHKWIS 354
>At2g17290 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 544
Score = 143 bits (361), Expect = 4e-34
Identities = 92/264 (34%), Positives = 130/264 (48%), Gaps = 6/264 (2%)
Query: 46 YIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQL-NH 104
Y + LG G FG I++G + + ++ + E+ I+ L H
Sbjct: 85 YTLSRKLGQGQFGTTYLCTDIATGVDYACKSISKRKLISKE-DVEDVRREIQIMHHLAGH 143
Query: 105 PNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQR 164
NIV K +E +IV +L GGELFDRI+ +G + E A + K I+ V+ H
Sbjct: 144 KNIVTIKGAYEDPLYVHIVMELCAGGELFDRIIHRGHYSERKAAELTKIIVGVVEACHSL 203
Query: 165 NIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSG 224
++HRDLKPEN L +NK DD L DFG++ K ++ GS YVAPEVL
Sbjct: 204 GVMHRDLKPENFLLVNKDDDFSLKAIDFGLSVFFK-PGQIFKDVVGSPYYVAPEVLLKH- 261
Query: 225 HGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKEF 284
+G D+W+ GVI Y LL G PF AE+ G + G + F W +S +AK+
Sbjct: 262 YGPEADVWTAGVILYILLSGVPPFWAETQQGIFDAVLKGY--IDFDTDPWPVISDSAKDL 319
Query: 285 ILWALTVSPKRRPTATDLINDIWI 308
I L SP R TA +++ WI
Sbjct: 320 IRKMLCSSPSERLTAHEVLRHPWI 343
>At2g46700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 595
Score = 143 bits (360), Expect = 6e-34
Identities = 105/303 (34%), Positives = 153/303 (49%), Gaps = 16/303 (5%)
Query: 14 KPEE-PEPVE-GHKLTKLFNKVTGQPSSYVNKSDYIFGKTLGAGTFGVVRQARCISSG-- 69
KP+E P P E G + + +K G ++ K Y GK +G G FG R
Sbjct: 111 KPKEGPIPEERGTEPEQSLDKSFGYGKNFGAK--YELGKEVGRGHFGHTCSGRGKKGDIK 168
Query: 70 ENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLN-HPNIVRFKDWFESKEKFYIVTQLAT 128
++ ++ ++ + E+ +L+ L+ H ++++ D E YIV +L
Sbjct: 169 DHPIAVKIISKAKMTTAIAIEDVRREVKLLKSLSGHKYLIKYYDACEDANNVYIVMELCD 228
Query: 129 GGELFDRILEKG-KFCEVDAVFIVKQILQGVQYLHQRNIVHRDLKPENILYLNKSDDSPL 187
GGEL DRIL +G K+ E DA IV QIL V + H + +VHRDLKPEN L+ + +DS L
Sbjct: 229 GGELLDRILARGGKYPEDDAKAIVVQILTVVSFCHLQGVVHRDLKPENFLFTSSREDSDL 288
Query: 188 VIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSGHGKPCDIWSIGVITYTLLCGYSP 247
+ DFG++ ++ D E ++ GS YVAPEVL S + DIWSIGVITY LLCG P
Sbjct: 289 KLIDFGLSDFIRPD-ERLNDIVGSAYYVAPEVLHRS-YSLEADIWSIGVITYILLCGSRP 346
Query: 248 FLAESADGFIEEC--TSGQYPVVFHKPYWNNVSKTAKEFILWALTVSPKRRPTATDLIND 305
F A + G T Y V W + S K+F+ L ++R +A +
Sbjct: 347 FWARTESGIFRTVLRTEPNYDDV----PWPSCSSEGKDFVKRLLNKDYRKRMSAVQALTH 402
Query: 306 IWI 308
W+
Sbjct: 403 PWL 405
>HsM4505103 [R] KOG0586 Serine/threonine protein kinase
Length = 713
Score = 142 bits (358), Expect = 1e-33
Identities = 93/290 (32%), Positives = 146/290 (50%), Gaps = 14/290 (4%)
Query: 45 DYIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNH 104
+Y KT+G G F V+ AR I +G S LQ L+ E+ I++ LNH
Sbjct: 55 NYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTS--LQKLFREVRIMKILNH 112
Query: 105 PNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQR 164
PNIV+ + E+++ Y++ + A+GG++FD ++ G+ E +A +QI+ VQY HQ+
Sbjct: 113 PNIVKLFEVIETQKTLYLIMEYASGGKVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQK 172
Query: 165 NIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSG 224
IVHRDLK EN+L D + I DFG + E +L GS Y APE+
Sbjct: 173 RIVHRDLKAENLLL---DADMNIKIADFGFSNEFTVGGKL-DTFCGSPPYAAPELFQGKK 228
Query: 225 H-GKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKE 283
+ G D+WS+GVI YTL+ G PF ++ E G+Y + F+ +S +
Sbjct: 229 YDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFY------MSTDCEN 282
Query: 284 FILWALTVSPKRRPTATDLINDIWITSTEKSTTDLLPEIRKGFDARKEFR 333
+ L ++P +R T ++ D WI + + +L P + D + R
Sbjct: 283 LLKRFLVLNPIKRGTLEQIMKDRWINAGHEE-DELKPFVEPELDISDQKR 331
>At5g45820 [T] KOG0583 Serine/threonine protein kinase
Length = 439
Score = 142 bits (357), Expect = 1e-33
Identities = 95/329 (28%), Positives = 156/329 (46%), Gaps = 25/329 (7%)
Query: 46 YIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNHP 105
Y G+ LG GTF V AR I +GE+ + + + E+S+++ + HP
Sbjct: 12 YELGRLLGQGTFAKVYHARNIKTGESVAIKVIDKQKVAKVGL-IDQIKREISVMRLVRHP 70
Query: 106 NIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRN 165
++V + SK K Y + GGELFD++ KGK E A +Q++ + Y H R
Sbjct: 71 HVVFLHEVMASKTKIYFAMEYVKGGELFDKV-SKGKLKENIARKYFQQLIGAIDYCHSRG 129
Query: 166 IVHRDLKPENILYLNKSDDSPLVIGDFGIA--KELKDDNELIHKAAGSMGYVAPEVLTSS 223
+ HRDLKPEN+L ++ L I DFG++ +E K + L+H G+ YVAPEV+
Sbjct: 130 VYHRDLKPENLLL---DENGDLKISDFGLSALRESKQQDGLLHTTCGTPAYVAPEVIGKK 186
Query: 224 GH-GKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAK 282
G+ G D+WS GV+ Y LL G+ PF ++ + T G+ F P W K
Sbjct: 187 GYDGAKADVWSCGVVLYVLLAGFLPFHEQNLVEMYRKITKGE----FKCPNW--FPPEVK 240
Query: 283 EFILWALTVSPKRRPTATDLINDIWI------TSTEKS-----TTDLLPEIRKGFDARKE 331
+ + L +P R ++ + W T KS L+ ++ F +
Sbjct: 241 KLLSRILDPNPNSRIKIEKIMENSWFQKGFKKIETPKSPESHQIDSLISDVHAAFSVKPM 300
Query: 332 FRDAVEIVKLNNRIKKLKVLYENQDESDT 360
+A +++ ++ L L+E ++ S++
Sbjct: 301 SYNAFDLISSLSQGFDLSGLFEKEERSES 329
>Hs13899225 [R] KOG0586 Serine/threonine protein kinase
Length = 688
Score = 141 bits (356), Expect = 2e-33
Identities = 91/279 (32%), Positives = 140/279 (49%), Gaps = 13/279 (4%)
Query: 31 NKVTGQPSSYVNKSDYIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQ 90
N + P + +Y +T+G G V+ AR I +G S LQ
Sbjct: 44 NSIASCPEEQPHVGNYRLLRTIGKGNSAKVKLARHILTGREVAIKIIDKTQLNPSS--LQ 101
Query: 91 MLYDELSILQQLNHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFI 150
L+ E+ I++ LNHPNIV+ + E+++ Y+V + A+ GE+FD ++ G+ E +A
Sbjct: 102 KLFREVRIMKGLNHPNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAK 161
Query: 151 VKQILQGVQYLHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAG 210
+QI+ V Y HQ+NIVHRDLK EN+L ++ + I DFG + E ++L G
Sbjct: 162 FRQIVSAVHYCHQKNIVHRDLKAENLLL---DAEANIKIADFGFSNEFTLGSKL-DTFCG 217
Query: 211 SMGYVAPEVLTSSGH-GKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVF 269
S Y APE+ + G DIWS+GVI YTL+ G PF + E G+Y V F
Sbjct: 218 SPPYAAPELFQGKKYDGPEVDIWSLGVILYTLVSGSLPFDGHNLKELRERVLRGKYRVPF 277
Query: 270 HKPYWNNVSKTAKEFILWALTVSPKRRPTATDLINDIWI 308
+ +S + + L ++P +R T ++ D WI
Sbjct: 278 Y------MSTDCESILRRFLVLNPAKRCTLEQIMKDKWI 310
>At2g38910 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 583
Score = 141 bits (356), Expect = 2e-33
Identities = 91/309 (29%), Positives = 150/309 (48%), Gaps = 12/309 (3%)
Query: 5 EPLSENNSRKPEEPEPVEGHKLTKL-----FNKVTGQPSSYVNKSDYIFGKTLGAGTFGV 59
+P++EN +P+ E H + V G+ + + K Y G+ LG G FG
Sbjct: 89 KPITENKEDPNSKPQKKEAHMKRMASAGLQIDSVLGRKTENL-KDIYSVGRKLGQGQFGT 147
Query: 60 VRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLN-HPNIVRFKDWFESKE 118
+G+ ++ + E+ I+ L+ HPN+++ +E
Sbjct: 148 TFLCVDKKTGKEFACKTIAKRKLTTPE-DVEDVRREIQIMHHLSGHPNVIQIVGAYEDAV 206
Query: 119 KFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRNIVHRDLKPENILY 178
++V ++ GGELFDRI+++G + E A + + I+ ++ H ++HRDLKPEN L+
Sbjct: 207 AVHVVMEICAGGELFDRIIQRGHYTEKKAAELARIIVGVIEACHSLGVMHRDLKPENFLF 266
Query: 179 LNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSGHGKPCDIWSIGVIT 238
++ +++ L DFG++ K E GS YVAPEVL + CD+WS GVI
Sbjct: 267 VSGDEEAALKTIDFGLSVFFK-PGETFTDVVGSPYYVAPEVLRKH-YSHECDVWSAGVII 324
Query: 239 YTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKEFILWALTVSPKRRPT 298
Y LL G PF E+ G E+ G + F W +VS++AK+ + L PK+R T
Sbjct: 325 YILLSGVPPFWDETEQGIFEQVLKGD--LDFISEPWPSVSESAKDLVRRMLIRDPKKRMT 382
Query: 299 ATDLINDIW 307
+++ W
Sbjct: 383 THEVLCHPW 391
>CE05507 [T] KOG0603 Ribosomal protein S6 kinase
Length = 785
Score = 141 bits (355), Expect = 2e-33
Identities = 97/297 (32%), Positives = 143/297 (47%), Gaps = 38/297 (12%)
Query: 52 LGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNHPNIVRFK 111
LG G F VVR+ + G Q Q L ++Q HPNIV+
Sbjct: 388 LGKGAFSVVRRCERVVDGAQFAVKIVSQKFAS----QAQREARILEMVQ--GHPNIVQLH 441
Query: 112 DWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRNIVHRDL 171
D FY+V ++ TG EL +RI + +F E +A I++Q++ V+YLH + IVHRDL
Sbjct: 442 DVHSDPLHFYLVMEILTGNELLERIRKLERFTESEAADIMRQLVSAVKYLHDKRIVHRDL 501
Query: 172 KPENILYLNKSDDSPLVIGDFGIAKELKDDNE-------LIHKAAG-------------- 210
KPENIL+ + + L + DFG A+ L + E ++ K G
Sbjct: 502 KPENILFESIDSSARLRLVDFGFARLLPNSMEQQLKSVQVLRKMYGLIAHNHSLHSETPC 561
Query: 211 -SMGYVAPEVL----TSSGHGKPCDIWSIGVITYTLLCGYSPFLA----ESADGFIEECT 261
++ Y APEVL + + + CD+WS+GV+ +T+L G PF A ESA ++
Sbjct: 562 FTLQYAAPEVLDVGDSQPEYNEQCDLWSLGVVLFTMLSGQVPFHARSRQESATEIMQRIC 621
Query: 262 SGQYPVVFHKPYWNNVSKTAKEFILWALTVSPKRRPTATDLINDIWITSTEKSTTDL 318
++ F W NVS AK I LTV PK+R + +L +W+ S+ T L
Sbjct: 622 RAEFS--FTGDAWTNVSADAKNLITGLLTVDPKKRLSMQELTAHMWLKSSASMDTPL 676
Score = 94.0 bits (232), Expect = 4e-19
Identities = 62/220 (28%), Positives = 110/220 (49%), Gaps = 10/220 (4%)
Query: 41 VNKSDYIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXG---QSVQLQMLYDELS 97
V+ ++ + LG G +G V R + ++ + L+ E
Sbjct: 12 VSMENFALLRVLGKGAYGKVFLVRKVGGKDHNTIYAMKVLRKTRVLTKQKTLEHTMAERQ 71
Query: 98 ILQQLNH-PNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQ 156
+L++L P +V F++ K +IV + GGELF + +G F A F++ +++
Sbjct: 72 VLERLRGTPFLVNLFYAFQTDTKLHIVMEYVRGGELFTHLCSRGHFDLEAARFVIAELVV 131
Query: 157 GVQYLHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAK-ELKDDNELIHKAAGSMGYV 215
+ LHQR +++RDLK ENIL ++ + + DFG++K L + + + G++ Y+
Sbjct: 132 AIDSLHQRKVIYRDLKLENILL---DEEGHVKLTDFGLSKLFLPGELDRANSYCGTIEYM 188
Query: 216 APEVLT--SSGHGKPCDIWSIGVITYTLLCGYSPFLAESA 253
+PEV+ G+ D WS+GVI++ LL G SPF + A
Sbjct: 189 SPEVINRPEGGYSDVVDWWSLGVISFELLTGCSPFTVDGA 228
>YMR001c [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 705
Score = 140 bits (354), Expect = 3e-33
Identities = 94/300 (31%), Positives = 140/300 (46%), Gaps = 20/300 (6%)
Query: 19 EPVEGHKLTKLFNKVTGQPSSYVNKS-DYIFGKTLGAGTFGVVRQARCIS----SGENXX 73
+P + K KL PS + DY G LG G F ARC SGE
Sbjct: 54 QPAQKKKREKLSALCKTPPSLIKTRGKDYHRGHFLGEGGF-----ARCFQIKDDSGEIFA 108
Query: 74 XXXXXXXXXXGQSVQLQMLYDELSILQQLNHPNIVRFKDWFESKEKFYIVTQLATGGELF 133
+ + ++L E+ I + ++HPNIV+F D FE YI+ ++ G L
Sbjct: 109 AKTVAKASIKSEKTRKKLL-SEIQIHKSMSHPNIVQFIDCFEDDSNVYILLEICPNGSLM 167
Query: 134 DRILEKGKFCEVDAVFIVKQILQGVQYLHQRNIVHRDLKPENILYLNKSDDSPLVIGDFG 193
+ + + E + F QI ++Y+H R ++HRDLK NI + + L IGDFG
Sbjct: 168 ELLKRRKVLTEPEVRFFTTQICGAIKYMHSRRVIHRDLKLGNIFF---DSNYNLKIGDFG 224
Query: 194 IAKELKDDNELIHKAAGSMGYVAPEVLTS--SGHGKPCDIWSIGVITYTLLCGYSPFLAE 251
+A L +++E + G+ Y+APEVL SGH DIWS+GV+ Y LL G PF A
Sbjct: 225 LAAVLANESERKYTICGTPNYIAPEVLMGKHSGHSFEVDIWSLGVMLYALLIGKPPFQAR 284
Query: 252 SADGFIEECTSGQYPVVFHKPYWNNVSKTAKEFILWALTVSPKRRPTATDLINDIWITST 311
+ E + KP +S K I L++ P RP+ T++++ +W T
Sbjct: 285 DVNTIYERIKCRDFSFPRDKP----ISDEGKILIRDILSLDPIERPSLTEIMDYVWFRGT 340
>Hs16950621 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 992
Score = 140 bits (354), Expect = 3e-33
Identities = 94/314 (29%), Positives = 164/314 (51%), Gaps = 21/314 (6%)
Query: 46 YIFGKTLGAGTFGVV-----RQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQ 100
Y + LG+G FG V ++ R + +G+ + + + E+SI+
Sbjct: 542 YDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAK---------EKENIRQEISIMN 592
Query: 101 QLNHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKG-KFCEVDAVFIVKQILQGVQ 159
L+HP +V+ D FE K +V ++ +GGELF+RI+++ + E + + ++QI +GV+
Sbjct: 593 CLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVE 652
Query: 160 YLHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEV 219
Y+H++ IVH DLKPENI+ +NK+ +I DFG+A+ L++ L G+ +VAPEV
Sbjct: 653 YIHKQGIVHLDLKPENIMCVNKTGTRIKLI-DFGLARRLENAGSL-KVLFGTPEFVAPEV 710
Query: 220 LTSSGHGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSK 279
+ G D+WSIGVI Y L+ G SPF+ ++ + + TS + F ++ +S
Sbjct: 711 INYEPIGYATDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATWD--FDDEAFDEISD 768
Query: 280 TAKEFILWALTVSPKRRPTATDLINDIWITSTEKS--TTDLLPEIRKGFDARKEFRDAVE 337
AK+FI L K R T + W+ K+ L + K + AR++++
Sbjct: 769 DAKDFISNLLKKDMKNRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYMARRKWQKTGN 828
Query: 338 IVKLNNRIKKLKVL 351
V+ R+ + ++
Sbjct: 829 AVRAIGRLSSMAMI 842
>Hs16950613 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 1845
Score = 140 bits (354), Expect = 3e-33
Identities = 94/314 (29%), Positives = 164/314 (51%), Gaps = 21/314 (6%)
Query: 46 YIFGKTLGAGTFGVV-----RQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQ 100
Y + LG+G FG V ++ R + +G+ + + + E+SI+
Sbjct: 1395 YDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAK---------EKENIRQEISIMN 1445
Query: 101 QLNHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKG-KFCEVDAVFIVKQILQGVQ 159
L+HP +V+ D FE K +V ++ +GGELF+RI+++ + E + + ++QI +GV+
Sbjct: 1446 CLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVE 1505
Query: 160 YLHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEV 219
Y+H++ IVH DLKPENI+ +NK+ +I DFG+A+ L++ L G+ +VAPEV
Sbjct: 1506 YIHKQGIVHLDLKPENIMCVNKTGTRIKLI-DFGLARRLENAGSL-KVLFGTPEFVAPEV 1563
Query: 220 LTSSGHGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSK 279
+ G D+WSIGVI Y L+ G SPF+ ++ + + TS + F ++ +S
Sbjct: 1564 INYEPIGYATDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATWD--FDDEAFDEISD 1621
Query: 280 TAKEFILWALTVSPKRRPTATDLINDIWITSTEKS--TTDLLPEIRKGFDARKEFRDAVE 337
AK+FI L K R T + W+ K+ L + K + AR++++
Sbjct: 1622 DAKDFISNLLKKDMKNRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYMARRKWQKTGN 1681
Query: 338 IVKLNNRIKKLKVL 351
V+ R+ + ++
Sbjct: 1682 AVRAIGRLSSMAMI 1695
>Hs16950611 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 1914
Score = 140 bits (354), Expect = 3e-33
Identities = 94/314 (29%), Positives = 164/314 (51%), Gaps = 21/314 (6%)
Query: 46 YIFGKTLGAGTFGVV-----RQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQ 100
Y + LG+G FG V ++ R + +G+ + + + E+SI+
Sbjct: 1464 YDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAK---------EKENIRQEISIMN 1514
Query: 101 QLNHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKG-KFCEVDAVFIVKQILQGVQ 159
L+HP +V+ D FE K +V ++ +GGELF+RI+++ + E + + ++QI +GV+
Sbjct: 1515 CLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVE 1574
Query: 160 YLHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEV 219
Y+H++ IVH DLKPENI+ +NK+ +I DFG+A+ L++ L G+ +VAPEV
Sbjct: 1575 YIHKQGIVHLDLKPENIMCVNKTGTRIKLI-DFGLARRLENAGSL-KVLFGTPEFVAPEV 1632
Query: 220 LTSSGHGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSK 279
+ G D+WSIGVI Y L+ G SPF+ ++ + + TS + F ++ +S
Sbjct: 1633 INYEPIGYATDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATWD--FDDEAFDEISD 1690
Query: 280 TAKEFILWALTVSPKRRPTATDLINDIWITSTEKS--TTDLLPEIRKGFDARKEFRDAVE 337
AK+FI L K R T + W+ K+ L + K + AR++++
Sbjct: 1691 DAKDFISNLLKKDMKNRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYMARRKWQKTGN 1750
Query: 338 IVKLNNRIKKLKVL 351
V+ R+ + ++
Sbjct: 1751 AVRAIGRLSSMAMI 1764
>Hs16950601 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 991
Score = 140 bits (354), Expect = 3e-33
Identities = 94/314 (29%), Positives = 164/314 (51%), Gaps = 21/314 (6%)
Query: 46 YIFGKTLGAGTFGVV-----RQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQ 100
Y + LG+G FG V ++ R + +G+ + + + E+SI+
Sbjct: 542 YDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAK---------EKENIRQEISIMN 592
Query: 101 QLNHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKG-KFCEVDAVFIVKQILQGVQ 159
L+HP +V+ D FE K +V ++ +GGELF+RI+++ + E + + ++QI +GV+
Sbjct: 593 CLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVE 652
Query: 160 YLHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEV 219
Y+H++ IVH DLKPENI+ +NK+ +I DFG+A+ L++ L G+ +VAPEV
Sbjct: 653 YIHKQGIVHLDLKPENIMCVNKTGTRIKLI-DFGLARRLENAGSL-KVLFGTPEFVAPEV 710
Query: 220 LTSSGHGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSK 279
+ G D+WSIGVI Y L+ G SPF+ ++ + + TS + F ++ +S
Sbjct: 711 INYEPIGYATDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATWD--FDDEAFDEISD 768
Query: 280 TAKEFILWALTVSPKRRPTATDLINDIWITSTEKS--TTDLLPEIRKGFDARKEFRDAVE 337
AK+FI L K R T + W+ K+ L + K + AR++++
Sbjct: 769 DAKDFISNLLKKDMKNRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYMARRKWQKTGN 828
Query: 338 IVKLNNRIKKLKVL 351
V+ R+ + ++
Sbjct: 829 AVRAIGRLSSMAMI 842
>At3g49370 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 594
Score = 140 bits (354), Expect = 3e-33
Identities = 91/268 (33%), Positives = 141/268 (51%), Gaps = 10/268 (3%)
Query: 46 YIFGKTLGAGTFGVVRQARCISS---GENXXXXXXXXXXXXGQSVQLQMLYDELSILQQL 102
Y G+ +G G FG A+ G+ ++ ++ + E+ +L+ L
Sbjct: 142 YELGREVGRGHFGHTCWAKAKKGKIKGQTVAVKIISKSKMTS-ALSIEDVRREVKLLKAL 200
Query: 103 N-HPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKG-KFCEVDAVFIVKQILQGVQY 160
+ H ++V+F D FE + ++V +L GGEL D IL +G ++ E +A I+ QIL +
Sbjct: 201 SGHSHMVKFYDVFEDSDNVFVVMELCEGGELLDSILARGGRYPEAEAKRILVQILSATAF 260
Query: 161 LHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVL 220
H + +VHRDLKPEN L+ +K++D+ L + DFG++ + D L + GS YVAPEVL
Sbjct: 261 FHLQGVVHRDLKPENFLFTSKNEDAVLKVIDFGLSDYARFDQRL-NDVVGSAYYVAPEVL 319
Query: 221 TSSGHGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKT 280
S + DIWSIGVI+Y LLCG PF + + I C P P W ++S
Sbjct: 320 HRS-YSTEADIWSIGVISYILLCGSRPFYGRT-ESAIFRCVLRANPNFDDLP-WPSISPI 376
Query: 281 AKEFILWALTVSPKRRPTATDLINDIWI 308
AK+F+ L ++R TA + W+
Sbjct: 377 AKDFVKRLLNKDHRKRMTAAQALAHPWL 404
>7304283 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 7175
Score = 140 bits (354), Expect = 3e-33
Identities = 84/285 (29%), Positives = 152/285 (52%), Gaps = 12/285 (4%)
Query: 29 LFNKVTGQPSSYVNKS---DYIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQ 85
+++K QP +S Y + +G G FGVV + R S+G
Sbjct: 6118 IYSKFVPQPVEISQQSVYDRYDILEEIGTGAFGVVHRCRERSTGN----IFAAKFIPVSH 6173
Query: 86 SVQLQMLYDELSILQQLNHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKG-KFCE 144
SV+ ++ E+ I+ QL+H ++ D FE ++ ++ + +GGELF+RI +G E
Sbjct: 6174 SVEKDLIRREIDIMNQLHHQKLINLHDAFEDDDEMILILEFLSGGELFERITAEGYVMTE 6233
Query: 145 VDAVFIVKQILQGVQYLHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNEL 204
+ + ++QI +G++++H++NI+H D+KPENI+ +S + +I DFG+A L D NE+
Sbjct: 6234 AEVINYMRQICEGIRHMHEQNIIHLDIKPENIMCQTRSSTNVKLI-DFGLATRL-DPNEV 6291
Query: 205 IHKAAGSMGYVAPEVLTSSGHGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQ 264
+ G+ + APE++ G D+W+ GV++Y LL G SPF ++ ++ +
Sbjct: 6292 VKITTGTAEFAAPEIVNREPVGFYTDMWATGVLSYVLLSGLSPFAGDNDVQTLKNVKACD 6351
Query: 265 YPVVFHKPYWNNVSKTAKEFILWALTVSPKRRPTATDLINDIWIT 309
+ F + +S+ AK+FI L + ++R TA + + W+T
Sbjct: 6352 WD--FDVESFKYISEEAKDFIRKLLVRNKEKRMTAHECLLHPWLT 6394
>Hs4758192 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 414
Score = 140 bits (353), Expect = 4e-33
Identities = 84/266 (31%), Positives = 148/266 (55%), Gaps = 8/266 (3%)
Query: 49 GKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNHPNIV 108
G+ LG G F VVR+ SG+ GQ +++++++ + ++P ++
Sbjct: 64 GRELGRGKFAVVRKCIKKDSGKEFAAKFMRKRRK-GQDCRMEIIHEIAVLELAQDNPWVI 122
Query: 109 RFKDWFESKEKFYIVTQLATGGELFDRIL--EKGKFCEVDAVFIVKQILQGVQYLHQRNI 166
+ +E+ + +V + A GGE+FD+ + + F E D +++QIL+GV +LH R++
Sbjct: 123 NLHEVYETASEMILVLEYAAGGEIFDQCVADREEAFKEKDVQRLMRQILEGVHFLHTRDV 182
Query: 167 VHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSGHG 226
VH DLKP+NIL ++S + I DFG+++ LK+ EL + G+ YVAPE+L+
Sbjct: 183 VHLDLKPQNILLTSESPLGDIKIVDFGLSRILKNSEEL-REIMGTPEYVAPEILSYDPIS 241
Query: 227 KPCDIWSIGVITYTLLCGYSPFLA-ESADGFIEECTSGQYPVVFHKPYWNNVSKTAKEFI 285
D+WSIGV+TY +L G SPFL + + F+ Q + + + ++ +S++A +FI
Sbjct: 242 MATDMWSIGVLTYVMLTGISPFLGNDKQETFL---NISQMNLSYSEEEFDVLSESAVDFI 298
Query: 286 LWALTVSPKRRPTATDLINDIWITST 311
L P+ R TA + + W+T +
Sbjct: 299 RTLLVKKPEDRATAEECLKHPWLTQS 324
>At4g24400 [T] KOG0583 Serine/threonine protein kinase
Length = 445
Score = 140 bits (353), Expect = 4e-33
Identities = 84/263 (31%), Positives = 133/263 (49%), Gaps = 11/263 (4%)
Query: 46 YIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNHP 105
Y G+T+G GTF V+ A+ +GE+ + + + + E+SI++ + HP
Sbjct: 9 YELGRTIGEGTFAKVKFAQNTETGESVAMKIVDRSTIIKRKM-VDQIKREISIMKLVRHP 67
Query: 106 NIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRN 165
+VR + S+ K YI+ + TGGELFD+I+ G+ E +A Q++ GV Y H +
Sbjct: 68 CVVRLYEVLASRTKIYIILEYITGGELFDKIVRNGRLSESEARKYFHQLIDGVDYCHSKG 127
Query: 166 IVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSGH 225
+ HRDLKPEN+L ++ + L I DFG++ + ++ G+ YVAPEVL+ G+
Sbjct: 128 VYHRDLKPENLLLDSQGN---LKISDFGLSALPEQGVTILKTTCGTPNYVAPEVLSHKGY 184
Query: 226 -GKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKEF 284
G DIWS GVI Y L+ GY PF + ++ + + AK
Sbjct: 185 NGAVADIWSCGVILYVLMAGYLPFDEMDLPTLYSKIDKAEFSCPSY------FALGAKSL 238
Query: 285 ILWALTVSPKRRPTATDLINDIW 307
I L +P+ R T ++ D W
Sbjct: 239 INRILDPNPETRITIAEIRKDEW 261
>7299438 [R] KOG0586 Serine/threonine protein kinase
Length = 705
Score = 140 bits (352), Expect = 5e-33
Identities = 100/322 (31%), Positives = 148/322 (45%), Gaps = 19/322 (5%)
Query: 6 PLSENNSRKPEEPEPVEGHKLTK---LFNKVTGQPSSYVNKSD---YIFGKTLGAGTFGV 59
P + N + P P G L + SYVN + Y KTLG G F
Sbjct: 52 PTTSNATALPATPTVAAGQDLGDGACSSKNTDSKFQSYVNGNGNGVYKIIKTLGKGNFAK 111
Query: 60 VRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNHPNIVRFKDWFESKEK 119
V+ A + +G + Q LY E+ I++ LNHPNIVR ES+
Sbjct: 112 VKLAIHVPTGREVAIKVIDKTQLNTSA--RQKLYREVKIMKLLNHPNIVRLFQVIESERT 169
Query: 120 FYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRNIVHRDLKPENILYL 179
Y+V + A+ GELFD +++ G+ E DA I +Q++ +QY H + +VHRDLK EN+L
Sbjct: 170 LYLVMEYASRGELFDHLVKNGRMRERDARVIFRQLVSAIQYCHSKFVVHRDLKAENLLL- 228
Query: 180 NKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSGHGKP-CDIWSIGVIT 238
+ I DFG D N + GS Y APE+ + P D WS+GV+
Sbjct: 229 --DQHMNIKIADFGFGNTF-DPNAQLETFCGSPPYAAPELFMGRKYAGPEVDAWSLGVVL 285
Query: 239 YTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKEFILWALTVSPKRRPT 298
YTL+ G PF + E G+Y V PY+ +S + + L ++P +R +
Sbjct: 286 YTLVSGSLPFDGGTLKELRERVLRGKYRV----PYY--ISMDCENLMRKFLVLNPAKRTS 339
Query: 299 ATDLINDIWITSTEKSTTDLLP 320
+ +++D WI + L P
Sbjct: 340 LSAVMSDKWINLGHDESDRLRP 361
>7299437 [R] KOG0586 Serine/threonine protein kinase
Length = 604
Score = 139 bits (351), Expect = 6e-33
Identities = 95/293 (32%), Positives = 144/293 (48%), Gaps = 16/293 (5%)
Query: 39 SYVNKSDY---IFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDE 95
SYVN + Y KTLG G F V+ A + +G ++ Q LY E
Sbjct: 53 SYVNGNGYGVYKIIKTLGKGNFAKVKLAIHLPTGREVAIKLIDKTAL--NTIARQKLYRE 110
Query: 96 LSILQQLNHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQIL 155
++I+++LNHPNIVR ES+ Y+V + +GGELF+ +++ G+ E DA + +Q++
Sbjct: 111 VNIMKKLNHPNIVRLLQVIESERTLYLVMEYVSGGELFNYLVKNGRMRERDARVLFRQLV 170
Query: 156 QGVQYLHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYV 215
++Y H ++IVHRDLK EN+L L I DFG + + L GS Y
Sbjct: 171 SAIEYCHSKSIVHRDLKAENLLL---DQQMKLKIADFGFSTTFEPKAPL-ETFCGSPPYA 226
Query: 216 APEVLTSSGHGKP-CDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYW 274
APE+ + P D WS+GV+ YTL+ G PF + + G+Y V PY+
Sbjct: 227 APELFRGKKYSGPEVDSWSLGVVLYTLVSGSLPFDGTNLKELRDRVLRGKYRV----PYY 282
Query: 275 NNVSKTAKEFILWALTVSPKRRPTATDLINDIWITSTEKSTTDLLPEIRKGFD 327
VS + I L ++P +R + + ++ D WI + L P K D
Sbjct: 283 --VSIECESLIRKFLVLNPTQRTSLSAVMADRWINMGYEQGNGLRPFQEKPMD 333
>At1g48260 [T] KOG0583 Serine/threonine protein kinase
Length = 432
Score = 139 bits (350), Expect = 8e-33
Identities = 95/266 (35%), Positives = 131/266 (48%), Gaps = 15/266 (5%)
Query: 46 YIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNHP 105
Y G+TLG G V+ A +GE+ +V Q + E+ L+ L HP
Sbjct: 11 YELGRTLGEGNSAKVKFAIDTLTGESFAIKIIEKSCITRLNVSFQ-IKREIRTLKVLKHP 69
Query: 106 NIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRN 165
NIVR + SK K Y+V + TGG+LFDRI+ KGK E + +Q++ GV Y H +
Sbjct: 70 NIVRLHEVLASKTKIYMVLECVTGGDLFDRIVSKGKLSETQGRKMFQQLIDGVSYCHNKG 129
Query: 166 IVHRDLKPENILYLNKSDDSPLVIGDFG---IAKELKDDNELIHKAAGSMGYVAPEVLTS 222
+ HRDLK EN+L K + I DFG +++ ++D L+H GS YVAPEVL +
Sbjct: 130 VFHRDLKLENVLLDAKGH---IKITDFGLSALSQHYREDG-LLHTTCGSPNYVAPEVLAN 185
Query: 223 SGH-GKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTA 281
G+ G DIWS GVI Y +L G PF + + G P+ P W +S A
Sbjct: 186 EGYDGAASDIWSCGVILYVILTGCLPFDDANLAVICRKIFKGDPPI----PRW--ISLGA 239
Query: 282 KEFILWALTVSPKRRPTATDLINDIW 307
K I L +P R T + W
Sbjct: 240 KTMIKRMLDPNPVTRVTIAGIKAHDW 265
>YKL101w [D] KOG0588 Serine/threonine protein kinase
Length = 1518
Score = 139 bits (349), Expect = 1e-32
Identities = 85/270 (31%), Positives = 147/270 (53%), Gaps = 14/270 (5%)
Query: 95 ELSILQQLNHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQI 154
E+ I++ ++H N++ + +E+K + Y+V + GGELFD ++ KGK E +A+ KQI
Sbjct: 164 EIVIMKLISHTNVMALFEVWENKSELYLVLEYVDGGELFDYLVSKGKLPEREAIHYFKQI 223
Query: 155 LQGVQYLHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGY 214
++GV Y H NI HRDLKPEN+L K + + I DFG+A L+ N+L+ + GS Y
Sbjct: 224 VEGVSYCHSFNICHRDLKPENLLLDKK--NRRIKIADFGMA-ALELPNKLLKTSCGSPHY 280
Query: 215 VAPEVLTSSG-HGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPY 273
+PE++ HG P D+WS G++ + LL G+ PF ++ + + SG+Y +
Sbjct: 281 ASPEIVMGRPYHGGPSDVWSCGIVLFALLTGHLPFNDDNIKKLLLKVQSGKYQMP----- 335
Query: 274 WNNVSKTAKEFILWALTVSPKRRPTATDLINDIWITS-TEKSTTDLLPEIRKGFDARKEF 332
+N+S A++ I L + P++R T +++ I + +L ++RK AR +
Sbjct: 336 -SNLSSEARDLISKILVIDPEKRITTQEILKHPLIKKYDDLPVNKVLRKMRKDNMARGKS 394
Query: 333 RDAVEIVKLNNRIKKLKVLYENQDESDTDI 362
+ ++ N + V ++ E D I
Sbjct: 395 NSDLHLL---NNVSPSIVTLHSKGEIDESI 421
>YDR507c [D] KOG0588 Serine/threonine protein kinase
Length = 1142
Score = 139 bits (349), Expect = 1e-32
Identities = 93/269 (34%), Positives = 141/269 (51%), Gaps = 20/269 (7%)
Query: 49 GKTLGAGTFGVVRQARCISSGENXXXXXXXXXXX-----XGQSVQLQMLYD--------E 95
G+TLG G+ G V+ AR S+G+ G S+ D E
Sbjct: 22 GETLGLGSTGKVQLARNGSTGQEAAVKVISKAVFNTGNVSGTSIVGSTTPDALPYGIERE 81
Query: 96 LSILQQLNHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQIL 155
+ I++ LNHPN++R D +E+ Y+V + A GELF+ ++E+G E +A+ +QI+
Sbjct: 82 IIIMKLLNHPNVLRLYDVWETNTDLYLVLEYAEKGELFNLLVERGPLPEHEAIRFFRQII 141
Query: 156 QGVQYLHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYV 215
GV Y H IVHRDLKPEN+L +K + + I DFG+A L+ + +L+ + GS Y
Sbjct: 142 IGVSYCHALGIVHRDLKPENLLLDHKYN---IKIADFGMA-ALETEGKLLETSCGSPHYA 197
Query: 216 APEVLTSSGH-GKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYW 274
APE+++ + G D+WS GVI + LL G PF + DG I F P
Sbjct: 198 APEIVSGIPYQGFASDVWSCGVILFALLTGRLPF--DEEDGNIRTLLLKVQKGEFEMPSD 255
Query: 275 NNVSKTAKEFILWALTVSPKRRPTATDLI 303
+ +S+ A++ I LTV P+RR D++
Sbjct: 256 DEISREAQDLIRKILTVDPERRIKTRDIL 284
>Hs22057171 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 456
Score = 139 bits (349), Expect = 1e-32
Identities = 77/217 (35%), Positives = 128/217 (58%), Gaps = 5/217 (2%)
Query: 94 DELSILQQLNHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKG-KFCEVDAVFIVK 152
+E+S++ QL+H N+++ D FESK +V + GGELFDRI+++ E+D + +K
Sbjct: 218 NEISVMNQLDHANLIQLYDAFESKNDIVLVMEYVDGGELFDRIIDESYNLTELDTILFMK 277
Query: 153 QILQGVQYLHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSM 212
QI +G++++HQ I+H DLKPENIL +N+ D + I DFG+A+ K E + G+
Sbjct: 278 QICEGIRHMHQMYILHLDLKPENILCVNR-DAKQIKIIDFGLARRYK-PREKLKVNFGTP 335
Query: 213 GYVAPEVLTSSGHGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKP 272
++APEV+ P D+WS+GVI Y LL G SPFL ++ + + ++ +
Sbjct: 336 EFLAPEVVNYDFVSFPTDMWSVGVIAYMLLSGLSPFLGDNDAETLNNILACRWDL--EDE 393
Query: 273 YWNNVSKTAKEFILWALTVSPKRRPTATDLINDIWIT 309
+ ++S+ AKEFI L R +A++ + W++
Sbjct: 394 EFQDISEEAKEFISKLLIKEKSWRISASEALKHPWLS 430
>At5g25110 [T] KOG0583 Serine/threonine protein kinase
Length = 460
Score = 139 bits (349), Expect = 1e-32
Identities = 88/266 (33%), Positives = 136/266 (51%), Gaps = 16/266 (6%)
Query: 46 YIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNHP 105
Y G+ LG GTFG V + I++GE+ + + ++ + E+SI++ + HP
Sbjct: 15 YEMGRLLGKGTFGKVYYGKEITTGESVAIKIINKDQVKREGM-MEQIKREISIMRLVRHP 73
Query: 106 NIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRN 165
NIV K+ +K K + + + GGELF +I+ KGK E A +Q++ V + H R
Sbjct: 74 NIVELKEVMATKTKIFFIMEYVKGGELFSKIV-KGKLKEDSARKYFQQLISAVDFCHSRG 132
Query: 166 IVHRDLKPENILYLNKSDDSPLVIGDFGIA---KELKDDNELIHKAAGSMGYVAPEVLTS 222
+ HRDLKPEN+L ++ L + DFG++ +++ D L+H G+ YVAPEVL
Sbjct: 133 VSHRDLKPENLLV---DENGDLKVSDFGLSALPEQILQDG-LLHTQCGTPAYVAPEVLRK 188
Query: 223 SGH-GKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTA 281
G+ G DIWS G+I Y LL G+ PF E+ + + F P W S +
Sbjct: 189 KGYDGAKGDIWSCGIILYVLLAGFLPFQDENLMKMYRKIFKSE----FEYPPW--FSPES 242
Query: 282 KEFILWALTVSPKRRPTATDLINDIW 307
K I L V P +R + ++ W
Sbjct: 243 KRLISKLLVVDPNKRISIPAIMRTPW 268
>At2g38490 [T] KOG0583 Serine/threonine protein kinase
Length = 431
Score = 139 bits (349), Expect = 1e-32
Identities = 92/286 (32%), Positives = 140/286 (48%), Gaps = 30/286 (10%)
Query: 33 VTGQPSSYVNKSDYIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQML 92
VTG + Y GK LG+G F V QA + +G + VQ + L
Sbjct: 15 VTGDDNKSALFGKYDLGKLLGSGAFAKVYQAEDLQNGGESVAI---------KVVQKKRL 65
Query: 93 YD--------ELSILQQLNHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCE 144
D E+S++++L HP+IV + +K K Y V +LA GGELF R+ +F E
Sbjct: 66 KDGLTAHVKREISVMRRLRHPHIVLLSEVLATKTKIYFVMELAKGGELFSRV-TSNRFTE 124
Query: 145 VDAVFIVKQILQGVQYLHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIA--KELKDDN 202
+ +Q++ V+Y H R + HRDLKPEN+L ++ L + DFG++ KE +
Sbjct: 125 SLSRKYFRQLISAVRYCHARGVFHRDLKPENLLL---DENRDLKVSDFGLSAMKEQIHPD 181
Query: 203 ELIHKAAGSMGYVAPEVLTSSGH-GKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECT 261
++H G+ YVAPE+L G+ G DIWS GV+ + L GY PF + G +
Sbjct: 182 GMLHTLCGTPAYVAPELLLKKGYDGSKADIWSCGVVLFLLNAGYLPFRDPNIMGLYRKIH 241
Query: 262 SGQYPVVFHKPYWNNVSKTAKEFILWALTVSPKRRPTATDLINDIW 307
QY + P W S ++ + L +P+ R T +++ D W
Sbjct: 242 KAQYKL----PDW--TSSDLRKLLRRLLEPNPELRITVEEILKDPW 281
>YPL153c [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 821
Score = 138 bits (348), Expect = 1e-32
Identities = 89/276 (32%), Positives = 138/276 (49%), Gaps = 22/276 (7%)
Query: 47 IFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNHPN 106
I + +G G F V++A ++G+ G + + EL +LQ+LNHP
Sbjct: 199 IIDEVVGQGAFATVKKAIERTTGKTFAVKIISKRKVIGN---MDGVTRELEVLQKLNHPR 255
Query: 107 IVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRNI 166
IVR K ++E E +Y+V + +GG+L D + G E I +QIL ++Y+H I
Sbjct: 256 IVRLKGFYEDTESYYMVMEFVSGGDLMDFVAAHGAVGEDAGREISRQILTAIKYIHSMGI 315
Query: 167 VHRDLKPENILYLNKSDDSPLV-IGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTS--- 222
HRDLKP+NIL + DD LV I DFG+AK ++ + + G++ YVAPEV+
Sbjct: 316 SHRDLKPDNILI--EQDDPVLVKITDFGLAK-VQGNGSFMKTFCGTLAYVAPEVIRGKDT 372
Query: 223 ----------SGHGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKP 272
+ + D+WS+G + Y +L G+ PF + D ++ G Y K
Sbjct: 373 SVSPDEYEERNEYSSLVDMWSMGCLVYVILTGHLPFSGSTQDQLYKQIGRGSYHEGPLKD 432
Query: 273 YWNNVSKTAKEFILWALTVSPKRRPTATDLINDIWI 308
+ +S+ A++FI L V P R TA +N WI
Sbjct: 433 F--RISEEARDFIDSLLQVDPNNRSTAAKALNHPWI 466
>SPAC23A1.06c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 504
Score = 138 bits (348), Expect = 1e-32
Identities = 88/306 (28%), Positives = 150/306 (48%), Gaps = 36/306 (11%)
Query: 38 SSYVNKSDYIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELS 97
++Y Y + LG G F V +A I E+ + Q Q ++ E++
Sbjct: 57 ANYPGLEKYQLIENLGDGAFSQVYKAYSIDRKEHVAVKVIRKYEMNKK--QRQGVFKEVN 114
Query: 98 ILQQLNHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQG 157
I++++ H N+V D+ E+++ +++V +LA GGELF +I+ F E A I+ Q+ +
Sbjct: 115 IMRRVKHKNVVNLFDFVETEDFYHLVMELAEGGELFHQIVNFTYFSENLARHIIIQVAEA 174
Query: 158 VQYLHQ-RNIVHRDLKPENILYL-----------------NKSDD------------SPL 187
V++LH IVHRD+KPEN+L+ NK D+ +
Sbjct: 175 VKHLHDVCGIVHRDIKPENLLFQPIEYLPSQNYTPPSLEPNKLDEGMFLEGIGAGGIGRI 234
Query: 188 VIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSGHGKPCDIWSIGVITYTLLCGYSP 247
+I DFG +K + N G++GY APE++ + K D+W++G + +T+LCG+ P
Sbjct: 235 LIADFGFSKVVW--NSKTATPCGTVGYAAPEIVNDELYSKNVDMWAMGCVLHTMLCGFPP 292
Query: 248 FLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKEFILWALTVSPKRRPTATDLINDIW 307
F E+ + +G++ F P+W+++S +AK+ I LTV P+ R W
Sbjct: 293 FFDENIKDLASKVVNGEFE--FLSPWWDDISDSAKDLITHLLTVDPRERYDIHQFFQHPW 350
Query: 308 ITSTEK 313
I K
Sbjct: 351 IKGESK 356
>Hs5453882 [G] KOG0599 Phosphorylase kinase gamma subunit
Length = 387
Score = 138 bits (347), Expect = 2e-32
Identities = 92/266 (34%), Positives = 137/266 (50%), Gaps = 22/266 (8%)
Query: 52 LGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYD-------ELSILQQLN- 103
LG G VVR RCI + G S + + + E+ IL++++
Sbjct: 26 LGRGVSSVVR--RCIHKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEVDILRKVSG 83
Query: 104 HPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQ 163
HPNI++ KD +E+ F++V L GELFD + EK E + I++ +L+ + LH+
Sbjct: 84 HPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIMRALLEVICTLHK 143
Query: 164 RNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSS 223
NIVHRDLKPENIL D+ + + DFG + +L + E + + G+ Y+APE++ S
Sbjct: 144 LNIVHRDLKPENILL---DDNMNIKLTDFGFSCQL-EPGERLREVCGTPSYLAPEIIECS 199
Query: 224 ------GHGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNV 277
G+GK D+WS GVI YTLL G PF + SG Y F P W++
Sbjct: 200 MNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQ--FGSPEWDDY 257
Query: 278 SKTAKEFILWALTVSPKRRPTATDLI 303
S T K+ + L V P+ R TA + +
Sbjct: 258 SDTVKDLVSRFLVVQPQNRYTAEEAL 283
>CE28218 [D] KOG0588 Serine/threonine protein kinase
Length = 914
Score = 138 bits (347), Expect = 2e-32
Identities = 92/317 (29%), Positives = 160/317 (50%), Gaps = 16/317 (5%)
Query: 4 KEPLSENNSRKPEEPEPVEGHKLTKLFNKVTGQPSSYVNK-SDYIFGKTLGAGTFGVVRQ 62
KE L E NS+ + +++ N V+ +P + Y KTLG G G+V+
Sbjct: 6 KEVLGEINSKLAAVNNELSSKIMSE--NIVSTRPVAQAQYCGPYKLEKTLGKGQTGLVKT 63
Query: 63 ARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNHPNIVRFKDWFESKEKFYI 122
+G +SV LQ + E++I++ + HP+++ D +E+K+ Y+
Sbjct: 64 GTHCITGRKVAIKIVNKEKLS-ESV-LQKVEREIAIMKLIEHPHVLHLYDVYENKKYLYL 121
Query: 123 VTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRNIVHRDLKPENILYLNKS 182
+ + +GGELFD ++ KG+ +A +QI+ + + H NI HRDLKPEN+L ++
Sbjct: 122 LLEHVSGGELFDYLVRKGRLMSKEARKFFRQIISALDFCHAHNICHRDLKPENLLLDERN 181
Query: 183 DDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSGH-GKPCDIWSIGVITYTL 241
+ + + DFG+A L+ + ++ + GS Y PEV+ + G+ D+WS GVI Y L
Sbjct: 182 N---IKVADFGMA-SLQVEGSMLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILYAL 237
Query: 242 LCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKEFILWALTVSPKRRPTATD 301
L G PF ++ +E+ G VFH P++ V + + + V P +R + D
Sbjct: 238 LVGALPFDDDNLRNLLEKVKRG----VFHIPHF--VPADVQSLLRAMIEVDPGKRYSLAD 291
Query: 302 LINDIWITSTEKSTTDL 318
+ W++ T K+ +L
Sbjct: 292 VFKHPWVSGTTKADPEL 308
>At4g04710 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 575
Score = 138 bits (347), Expect = 2e-32
Identities = 112/347 (32%), Positives = 166/347 (47%), Gaps = 48/347 (13%)
Query: 33 VTGQPSSYVNKSDYIFGKTLGAGTFGVVRQA--RCISSGENXXXXXXXXXXXXGQSVQLQ 90
+ G+P + K Y FG LG G + R +SS E + +
Sbjct: 24 ILGKPLEDIKKH-YSFGDELGKGKSYACKSIPKRTLSSEE-----------------EKE 65
Query: 91 MLYDELSILQQLN-HPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGK----FCEV 145
+ E+ I+ ++ PNIV+ K +E +IV +L GGELFD+I K + E
Sbjct: 66 AVKTEIQIMDHVSGQPNIVQIKGSYEDNNSIHIVMELCGGGELFDKIDALVKSHSYYSEK 125
Query: 146 DAVFIVKQILQGVQYLHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELI 205
DA I + I+ V+ H ++VHRDLKPEN L+ +K +++ L DFG + +K + +
Sbjct: 126 DAAGIFRSIVNAVKICHSLDVVHRDLKPENFLFSSKDENAMLKAIDFGCSVYIK-EGKTF 184
Query: 206 HKAAGSMGYVAPEVLTSSGHGKPCDIWSIGVITYTLLCGYSPFLA--ES--------ADG 255
+ GS Y+APEVL S +GK DIWS GVI Y LL G PF ES D
Sbjct: 185 ERVVGSKYYIAPEVLEGS-YGKEIDIWSAGVILYILLSGVPPFQTGIESIIVSTLCIVDA 243
Query: 256 FIEECTSGQYPVVFHKPYWNNVSKTAKEFILWALTVSPKRRPTATDLINDIWITS--TEK 313
I+EC + F W +S AK I LT PK R +A D++ W+ S +K
Sbjct: 244 EIKECR-----LDFESQPWPLISFKAKHLIGKMLTKKPKERISAADVLEHPWMKSEAPDK 298
Query: 314 STTDLLPEIRKGFDARKEFRD-AVEIVK---LNNRIKKLKVLYENQD 356
+++ K F A + + A++++ IK LK ++EN D
Sbjct: 299 PIDNVVLSRMKQFRAMNKLKKLALKVIAEGLSEEEIKGLKTMFENMD 345
>Hs7662170 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 661
Score = 137 bits (346), Expect = 2e-32
Identities = 88/274 (32%), Positives = 137/274 (49%), Gaps = 13/274 (4%)
Query: 43 KSDYIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQL 102
K Y +TLG GT+G V++A SG + + + E+ I+ L
Sbjct: 52 KHRYELQETLGKGTYGKVKRATERFSGRVVAIKSIRKDKIKDEQDMVH-IRREIEIMSSL 110
Query: 103 NHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLH 162
NHP+I+ + FE+K+K I+ + A+ GEL+D I E+ + E + +QI+ V Y H
Sbjct: 111 NHPHIISIYEVFENKDKIVIIMEYASKGELYDYISERRRLSERETRHFFRQIVSAVHYCH 170
Query: 163 QRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTS 222
+ +VHRDLK ENIL D+ + I DFG++ L ++ + GS Y +PE++
Sbjct: 171 KNGVVHRDLKLENILL---DDNCNIKIADFGLS-NLYQKDKFLQTFCGSPLYASPEIVNG 226
Query: 223 SGH-GKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTA 281
+ G D W++GV+ YTL+ G PF I + +SG+Y +P A
Sbjct: 227 RPYRGPEVDSWALGVLLYTLVYGTMPFDGFDHKNLIRQISSGEY----REP---TQPSDA 279
Query: 282 KEFILWALTVSPKRRPTATDLINDIWITSTEKST 315
+ I W L V+P RR T D+ N W+ KS+
Sbjct: 280 RGLIRWMLMVNPDRRATIEDIANHWWVNWGYKSS 313
>CE18169 [T] KOG0603 Ribosomal protein S6 kinase
Length = 797
Score = 137 bits (346), Expect = 2e-32
Identities = 74/220 (33%), Positives = 119/220 (53%), Gaps = 7/220 (3%)
Query: 98 ILQQLNHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKF-CEVDAVFIVKQILQ 156
+L+ +H +V+ D +E + Y++ +L GGEL D+++ K E + I+ +L
Sbjct: 499 LLRHSHHQFVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEVAAIMANLLN 558
Query: 157 GVQYLHQRNIVHRDLKPENILY-LNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYV 215
VQYLH + + HRDL NIL+ L D S L I DFG AK+ + +N ++ + +V
Sbjct: 559 AVQYLHSQQVAHRDLTAANILFALKDGDPSSLRIVDFGFAKQSRAENGMLMTPCYTAQFV 618
Query: 216 APEVLTSSGHGKPCDIWSIGVITYTLLCGYSPFLA---ESADGFIEECTSGQYPVVFHKP 272
APEVL G+ + CD+WS+GV+ +T+L G +PF ++ D ++ G+ + P
Sbjct: 619 APEVLRKQGYDRSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQILQRVGDGK--ISMTHP 676
Query: 273 YWNNVSKTAKEFILWALTVSPKRRPTATDLINDIWITSTE 312
W+ +S AK+ + L V P RR TA + WI E
Sbjct: 677 VWDTISDEAKDLVRKMLDVDPNRRVTAKQALQHKWIGQKE 716
Score = 121 bits (304), Expect = 2e-27
Identities = 69/202 (34%), Positives = 108/202 (53%), Gaps = 8/202 (3%)
Query: 50 KTLGAGTFG---VVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNHPN 106
K LG G+FG +VR+ R SG + Q L E +IL ++HP
Sbjct: 108 KVLGQGSFGKVFLVRKVRGRDSGHVYAMKVLKKATLKVRDRQRTKL--ERNILAHISHPF 165
Query: 107 IVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRNI 166
IV+ F+++ K Y++ GG+LF R+ ++ F E D F + ++ +++LH I
Sbjct: 166 IVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEDDVKFYLAELTLALEHLHSLGI 225
Query: 167 VHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSGHG 226
V+RDLKPENIL D + + DFG++KE D + + G++ Y+APEV+ GH
Sbjct: 226 VYRDLKPENILL---DADGHIKVTDFGLSKEAIDSEKKTYSFCGTVEYMAPEVINRRGHS 282
Query: 227 KPCDIWSIGVITYTLLCGYSPF 248
D WS+GV+ + +L G+ PF
Sbjct: 283 MAADFWSLGVLMFEMLTGHLPF 304
>CE13014 [T] KOG0603 Ribosomal protein S6 kinase
Length = 740
Score = 137 bits (346), Expect = 2e-32
Identities = 74/220 (33%), Positives = 119/220 (53%), Gaps = 7/220 (3%)
Query: 98 ILQQLNHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKF-CEVDAVFIVKQILQ 156
+L+ +H +V+ D +E + Y++ +L GGEL D+++ K E + I+ +L
Sbjct: 442 LLRHSHHQFVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEVAAIMANLLN 501
Query: 157 GVQYLHQRNIVHRDLKPENILY-LNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYV 215
VQYLH + + HRDL NIL+ L D S L I DFG AK+ + +N ++ + +V
Sbjct: 502 AVQYLHSQQVAHRDLTAANILFALKDGDPSSLRIVDFGFAKQSRAENGMLMTPCYTAQFV 561
Query: 216 APEVLTSSGHGKPCDIWSIGVITYTLLCGYSPFLA---ESADGFIEECTSGQYPVVFHKP 272
APEVL G+ + CD+WS+GV+ +T+L G +PF ++ D ++ G+ + P
Sbjct: 562 APEVLRKQGYDRSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQILQRVGDGK--ISMTHP 619
Query: 273 YWNNVSKTAKEFILWALTVSPKRRPTATDLINDIWITSTE 312
W+ +S AK+ + L V P RR TA + WI E
Sbjct: 620 VWDTISDEAKDLVRKMLDVDPNRRVTAKQALQHKWIGQKE 659
Score = 121 bits (304), Expect = 2e-27
Identities = 69/202 (34%), Positives = 108/202 (53%), Gaps = 8/202 (3%)
Query: 50 KTLGAGTFG---VVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNHPN 106
K LG G+FG +VR+ R SG + Q L E +IL ++HP
Sbjct: 51 KVLGQGSFGKVFLVRKVRGRDSGHVYAMKVLKKATLKVRDRQRTKL--ERNILAHISHPF 108
Query: 107 IVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRNI 166
IV+ F+++ K Y++ GG+LF R+ ++ F E D F + ++ +++LH I
Sbjct: 109 IVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEDDVKFYLAELTLALEHLHSLGI 168
Query: 167 VHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSGHG 226
V+RDLKPENIL D + + DFG++KE D + + G++ Y+APEV+ GH
Sbjct: 169 VYRDLKPENILL---DADGHIKVTDFGLSKEAIDSEKKTYSFCGTVEYMAPEVINRRGHS 225
Query: 227 KPCDIWSIGVITYTLLCGYSPF 248
D WS+GV+ + +L G+ PF
Sbjct: 226 MAADFWSLGVLMFEMLTGHLPF 247
>CE00847 [T] KOG0583 Serine/threonine protein kinase
Length = 622
Score = 137 bits (346), Expect = 2e-32
Identities = 87/272 (31%), Positives = 138/272 (49%), Gaps = 14/272 (5%)
Query: 38 SSYVNKSDYIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELS 97
+ ++ +++ +T+G G FG V++ I +G + G + +E+
Sbjct: 16 TGHLKIGNFVIKETIGKGAFGAVKRGTHIQTGYDVAIKILNRGRMKGLGT-VNKTRNEID 74
Query: 98 ILQQLNHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQG 157
LQ+L HP+I R + ++V +L +GGELF I KG ++ +QI+ G
Sbjct: 75 NLQKLTHPHITRLFRVISTPSDIFLVMELVSGGELFSYITRKGALPIRESRRYFQQIISG 134
Query: 158 VQYLHQRNIVHRDLKPENILY-LNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVA 216
V Y H IVHRDLKPEN+L NK+ + I DFG++ + D +L+ A GS Y A
Sbjct: 135 VSYCHNHMIVHRDLKPENLLLDANKN----IKIADFGLSNYM-TDGDLLSTACGSPNYAA 189
Query: 217 PEVLTSSGH-GKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWN 275
PE++++ + G D+WS GVI Y +LCG PF ++ + SG+Y V PY
Sbjct: 190 PELISNKLYVGPEVDLWSCGVILYAMLCGTLPFDDQNVPTLFAKIKSGRYTV----PY-- 243
Query: 276 NVSKTAKEFILWALTVSPKRRPTATDLINDIW 307
++ K A + I L V P +R ++N W
Sbjct: 244 SMEKQAADLISTMLQVDPVKRADVKRIVNHSW 275
>At5g01820 [T] KOG0583 Serine/threonine protein kinase
Length = 442
Score = 137 bits (346), Expect = 2e-32
Identities = 90/268 (33%), Positives = 136/268 (50%), Gaps = 20/268 (7%)
Query: 46 YIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXX--GQSVQLQMLYDELSILQQLN 103
Y GK +G G F V R ++G++ G + +Q E++I+ +L
Sbjct: 22 YEVGKLVGCGAFAKVYHGRSTATGQSVAIKVVSKQRLQKGGLNGNIQR---EIAIMHRLR 78
Query: 104 HPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQ 163
HP+IVR + +K K + V + A GGELF ++ KG+FCE + +Q++ V Y H
Sbjct: 79 HPSIVRLFEVLATKSKIFFVMEFAKGGELFAKV-SKGRFCEDLSRRYFQQLISAVGYCHS 137
Query: 164 RNIVHRDLKPENILYLNKSDDSPLVIGDFGIA---KELKDDNELIHKAAGSMGYVAPEVL 220
R I HRDLKPEN+L K D L I DFG++ +++ D L+H G+ YVAPEVL
Sbjct: 138 RGIFHRDLKPENLLLDEKLD---LKISDFGLSALTDQIRPDG-LLHTLCGTPAYVAPEVL 193
Query: 221 TSSGH-GKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSK 279
G+ G DIWS G+I + L GY PF + + G++ + P W S
Sbjct: 194 AKKGYDGAKIDIWSCGIILFVLNAGYLPFNDHNLMVMYRKIYKGEFRI----PKW--TSP 247
Query: 280 TAKEFILWALTVSPKRRPTATDLINDIW 307
+ + L +P+ R T ++I+D W
Sbjct: 248 DLRRLLTRLLDTNPQTRITIEEIIHDPW 275
>At4g04700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 347
Score = 137 bits (346), Expect = 2e-32
Identities = 88/263 (33%), Positives = 141/263 (53%), Gaps = 10/263 (3%)
Query: 46 YIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLN-H 104
YI G+ LG G FG+ R+ S+G+ + + + + E+ I++QL+
Sbjct: 28 YILGEELGRGNFGLTRKCVEKSTGKTFACKTILKTKLKDEECE-EDVKREIRIMKQLSGE 86
Query: 105 PNIVRFKDWFESKEKFYIVTQLATGGELFDRIL---EKGK-FCEVDAVFIVKQILQGVQY 160
PNIV FK+ +E K+ +IV + GGEL+D+IL + GK + E +A I++ I+ V+
Sbjct: 87 PNIVEFKNAYEDKDSVHIVMEYCGGGELYDKILALYDVGKSYSEKEAAGIIRSIVNVVKN 146
Query: 161 LHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVL 220
H ++HRDLKPEN L + D++ + + DFG + + ++ ++ AGS Y+APEVL
Sbjct: 147 CHYMGVMHRDLKPENFLLTSNDDNATVKVIDFGCSVFI-EEGKVYQDLAGSDYYIAPEVL 205
Query: 221 TSSGHGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKT 280
+GK DIWS G+I Y LLCG SPF+ E E S + + + W
Sbjct: 206 -QGNYGKEADIWSAGIILYILLCGKSPFVKEPEGQMFNEIKS--LEIDYSEEPWPLRDSR 262
Query: 281 AKEFILWALTVSPKRRPTATDLI 303
A + L +PK R +A +++
Sbjct: 263 AIHLVKRMLDRNPKERISAAEVL 285
>Hs4502567_1 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 360
Score = 137 bits (346), Expect = 2e-32
Identities = 89/303 (29%), Positives = 154/303 (50%), Gaps = 18/303 (5%)
Query: 46 YIFGKTLGAGTFGVVRQARCIS--SGENXXXXXXXXXXXXGQ-SVQLQMLYDELSILQQL 102
Y + +G G F VVR RCI+ +G+ + + L E SI L
Sbjct: 12 YELCEVIGKGPFSVVR--RCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASICHML 69
Query: 103 NHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGK----FCEVDAVFIVKQILQGV 158
HP+IV + + S Y+V + G +L I+++ + E A ++QIL+ +
Sbjct: 70 KHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILEAL 129
Query: 159 QYLHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPE 218
+Y H NI+HRD+KP +L +K + +P+ +G FG+A +L + + G+ ++APE
Sbjct: 130 RYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMAPE 189
Query: 219 VLTSSGHGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVS 278
V+ +GKP D+W GVI + LL G PF + + E G+Y + + W+++S
Sbjct: 190 VVKREPYGKPVDVWGCGVILFILLSGCLPFYG-TKERLFEGIIKGKYKM--NPRQWSHIS 246
Query: 279 KTAKEFILWALTVSPKRRPTATDLINDIWITSTEKSTTDL-LPE----IRKGFDARKEFR 333
++AK+ + L + P R T + +N W+ ++ + LPE +RK F+AR++ +
Sbjct: 247 ESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYAYKIHLPETVEQLRK-FNARRKLK 305
Query: 334 DAV 336
AV
Sbjct: 306 GAV 308
>Hs4505785 [G] KOG0599 Phosphorylase kinase gamma subunit
Length = 406
Score = 137 bits (345), Expect = 3e-32
Identities = 101/306 (33%), Positives = 146/306 (47%), Gaps = 26/306 (8%)
Query: 52 LGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYD----ELSILQQL-NHPN 106
+G G VVR+ ++G QL+ + + E IL+Q+ HP+
Sbjct: 30 IGRGVSSVVRRCVHRATGHEFAVKIMEVTAERLSPEQLEEVREATRRETHILRQVAGHPH 89
Query: 107 IVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRNI 166
I+ D +ES ++V L GELFD + EK E + I++ +L+ V +LH NI
Sbjct: 90 IITLIDSYESSSFMFLVFDLMRKGELFDYLTEKVALSEKETRSIMRSLLEAVSFLHANNI 149
Query: 167 VHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVL------ 220
VHRDLKPENIL D+ + + DFG + L + E + + G+ GY+APE+L
Sbjct: 150 VHRDLKPENILL---DDNMQIRLSDFGFSCHL-EPGEKLRELCGTPGYLAPEILKCSMDE 205
Query: 221 TSSGHGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKT 280
T G+GK D+W+ GVI +TLL G PF + GQY F P W++ S T
Sbjct: 206 THPGYGKEVDLWACGVILFTLLAGSPPFWHRRQILMLRMIMEGQYQ--FSSPEWDDRSST 263
Query: 281 AKEFILWALTVSPKRRPTATDLINDIWITSTEKSTT-DLLPEIRKGFDARKEFRDAVEIV 339
K+ I L V P+ R TA + + E S +L P R+ FR AV V
Sbjct: 264 VKDLISRLLQVDPEARLTAEQALQHPFFERCEGSQPWNLTP--------RQRFRVAVWTV 315
Query: 340 KLNNRI 345
R+
Sbjct: 316 LAAGRV 321
>At5g10930 [T] KOG0583 Serine/threonine protein kinase
Length = 445
Score = 136 bits (343), Expect = 5e-32
Identities = 91/267 (34%), Positives = 130/267 (48%), Gaps = 15/267 (5%)
Query: 46 YIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNHP 105
Y G+ LG GTF V + I GE + ++ + E+SI++ + HP
Sbjct: 12 YEMGRLLGKGTFAKVYYGKEIIGGECVAIKVINKDQVMKRPGMMEQIKREISIMKLVRHP 71
Query: 106 NIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRN 165
NIV K+ +K K + V + GGELF +I KGK E A +Q++ V Y H R
Sbjct: 72 NIVELKEVMATKTKIFFVMEFVKGGELFCKI-SKGKLHEDAARRYFQQLISAVDYCHSRG 130
Query: 166 IVHRDLKPENILYLNKSDDSPLVIGDFGIA---KELKDDNELIHKAAGSMGYVAPEVLTS 222
+ HRDLKPEN+L ++ L I DFG++ +++ D L+H G+ YVAPEVL
Sbjct: 131 VSHRDLKPENLLL---DENGDLKISDFGLSALPEQILQDG-LLHTQCGTPAYVAPEVLKK 186
Query: 223 SGH-GKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTA 281
G+ G DIWS GV+ Y LL G PF E+ + + F P W S A
Sbjct: 187 KGYDGAKADIWSCGVVLYVLLAGCLPFQDENLMNMYRKI----FRADFEFPPW--FSPEA 240
Query: 282 KEFILWALTVSPKRRPTATDLINDIWI 308
+ I L V P RR + ++ W+
Sbjct: 241 RRLISKLLVVDPDRRISIPAIMRTPWL 267
>At4g30960 [T] KOG0583 Serine/threonine protein kinase
Length = 441
Score = 136 bits (343), Expect = 5e-32
Identities = 90/281 (32%), Positives = 137/281 (48%), Gaps = 16/281 (5%)
Query: 31 NKVTGQPSSYVNKSDYIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQ 90
N G S+ + Y G+ LG GTF V AR I +G++ + +
Sbjct: 9 NGSDGGSSTGLLHGRYELGRLLGHGTFAKVYHARNIQTGKSVAMKVVGKEKVVKVGM-VD 67
Query: 91 MLYDELSILQQLNHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFI 150
+ E+S+++ + HPNIV + SK K Y +L GGELF ++ KG+ E A
Sbjct: 68 QIKREISVMRMVKHPNIVELHEVMASKSKIYFAMELVRGGELFAKV-AKGRLREDVARVY 126
Query: 151 VKQILQGVQYLHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIA---KELKDDNELIHK 207
+Q++ V + H R + HRDLKPEN+L ++ L + DFG++ + LK D L+H
Sbjct: 127 FQQLISAVDFCHSRGVYHRDLKPENLLL---DEEGNLKVTDFGLSAFTEHLKQDG-LLHT 182
Query: 208 AAGSMGYVAPEVLTSSGH-GKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYP 266
G+ YVAPEV+ G+ G D+WS GVI + LL GY PF ++ + G
Sbjct: 183 TCGTPAYVAPEVILKKGYDGAKADLWSCGVILFVLLAGYLPFQDDNLVNMYRKIYRGD-- 240
Query: 267 VVFHKPYWNNVSKTAKEFILWALTVSPKRRPTATDLINDIW 307
F P W +S A+ + L +P R T +++ W
Sbjct: 241 --FKCPGW--LSSDARRLVTKLLDPNPNTRITIEKVMDSPW 277
>YLR248w [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 610
Score = 136 bits (342), Expect = 7e-32
Identities = 78/246 (31%), Positives = 124/246 (49%), Gaps = 40/246 (16%)
Query: 107 IVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRNI 166
IV F D+ E+ +YI+ +L TGGE+F I+ F E + ++KQ+ V+++H +
Sbjct: 250 IVAFIDFQETDSYYYIIQELLTGGEIFGEIVRLTYFSEDLSRHVIKQLALAVKHMHSLGV 309
Query: 167 VHRDLKPENILY------------LNKSDDSP-------------------LVIGDFGIA 195
VHRD+KPEN+L+ L KSDD + + DFG++
Sbjct: 310 VHRDIKPENLLFEPIEFTRSIKPKLRKSDDPQTKADEGIFTPGVGGGGIGIVKLADFGLS 369
Query: 196 KELKDDNELIHKAAGSMGYVAPEVLTSSGHGKPCDIWSIGVITYTLLCGYSPFLAESADG 255
K++ N G++GY APEV+ + D+W IG + YT+LCG+ PF E D
Sbjct: 370 KQIFSKN--TKTPCGTVGYTAPEVVKDEHYSMKVDMWGIGCVLYTMLCGFPPFYDEKIDT 427
Query: 256 FIEECTSGQYPVVFHKPYWNNVSKTAKEFILWALTVSPKRRPTATDLINDIWITSTEKST 315
E+ + G+Y F KP+W+ +S AK + L + P +R ++D W+ +T
Sbjct: 428 LTEKISRGEY--TFLKPWWDEISAGAKNAVAKLLELEPSKRYDIDQFLDDPWL-----NT 480
Query: 316 TDLLPE 321
D LP+
Sbjct: 481 FDCLPK 486
>7290249 [R] KOG0586 Serine/threonine protein kinase
Length = 1398
Score = 136 bits (342), Expect = 7e-32
Identities = 90/265 (33%), Positives = 134/265 (49%), Gaps = 15/265 (5%)
Query: 46 YIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNHP 105
Y +T+G G F VV+ AR + +N Q+ LQ +Y E+ I+++L HP
Sbjct: 141 YDIERTIGKGNFAVVKLARHRIT-KNEVAIKIIDKSQLDQT-NLQKVYREVEIMKRLKHP 198
Query: 106 NIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRN 165
+I++ E+K YIV++ A+ GE+FD I + G+ E A F QI+ V+Y H++
Sbjct: 199 HIIKLYQVMETKNMIYIVSEYASQGEIFDYIAKYGRMSESAARFKFWQIISAVEYCHKKG 258
Query: 166 IVHRDLKPENILY-LNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSG 224
IVHRDLK EN+L LN + + I DFG + K EL+ GS Y APEV
Sbjct: 259 IVHRDLKAENLLLDLNMN----IKIADFGFSNHFK-PGELLATWCGSPPYAAPEVFEGKQ 313
Query: 225 H-GKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKE 283
+ G DIWS+GV+ Y L+CG PF + + SG++ + F +S +
Sbjct: 314 YTGPEIDIWSLGVVLYVLVCGALPFDGSTLQSLRDRVLSGRFRIPFF------MSSECEH 367
Query: 284 FILWALTVSPKRRPTATDLINDIWI 308
I L + P RR T + W+
Sbjct: 368 LIRRMLVLEPTRRYTIDQIKRHRWM 392
>Hs6005922_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 302
Score = 136 bits (342), Expect = 7e-32
Identities = 92/295 (31%), Positives = 141/295 (47%), Gaps = 12/295 (4%)
Query: 52 LGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNHPNIVRFK 111
LG G F VV+ +C G + ++ + EL ILQ L HP +V
Sbjct: 7 LGRGRFSVVK--KCDQKGTKRAVATKFVNK---KLMKRDQVTHELGILQSLQHPLLVGLL 61
Query: 112 DWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRNIVHRDL 171
D FE+ + +V ++A G L D ++ G E + ++L+ V+YLH I H DL
Sbjct: 62 DTFETPTSYILVLEMADQGRLLDCVVRWGSLTEGKIRAHLGEVLEAVRYLHNCRIAHLDL 121
Query: 172 KPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSGHGKPCDI 231
KPENIL + + DFG A +L + IH+ G+ + APE++ + D
Sbjct: 122 KPENILVDESLAKPTIKLADFGDAVQL-NTTYYIHQLLGNPEFAAPEIILGNPVSLTSDT 180
Query: 232 WSIGVITYTLLCGYSPFLAESADGFIEECTS-GQYPVVFHKPYWNNVSKTAKEFILWALT 290
WS+GV+TY LL G SPFL +S + E C + + F Y+ VS+ AKEF+ + L
Sbjct: 181 WSVGVLTYVLLSGVSPFLDDSVE---ETCLNICRLDFSFPDDYFKGVSQKAKEFVCFLLQ 237
Query: 291 VSPKRRPTATDLINDIWITSTEKSTTDLLPEIR--KGFDARKEFRDAVEIVKLNN 343
P +RP+A + + W+ + +T +L R + RK D I + N
Sbjct: 238 EDPAKRPSAALALQEQWLQAGNGRSTGVLDTSRLTSFIERRKHQNDVRPIRSIKN 292
>7302464 [R] KOG0586 Serine/threonine protein kinase
Length = 739
Score = 135 bits (341), Expect = 9e-32
Identities = 82/260 (31%), Positives = 135/260 (51%), Gaps = 13/260 (5%)
Query: 50 KTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNHPNIVR 109
KT+G G F V+ A+ + +G+ S LQ L+ E+ I++ L+HPNIV+
Sbjct: 155 KTIGKGNFAKVKLAKHLPTGKEVAIKIIDKTQLNPGS--LQKLFREVRIMKMLDHPNIVK 212
Query: 110 FKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRNIVHR 169
E+++ Y++ + A+GGE+FD ++ G+ E +A +QI+ VQY HQ+ I+HR
Sbjct: 213 LFQVIETEKTLYLIMEYASGGEVFDYLVLHGRMKEKEARVKFRQIVSAVQYCHQKRIIHR 272
Query: 170 DLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSGH-GKP 228
DLK EN+L + + I DFG + E ++L GS Y APE+ + G
Sbjct: 273 DLKAENLLL---DSELNIKIADFGFSNEFTPGSKL-DTFCGSPPYAAPELFQGKKYDGPE 328
Query: 229 CDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKEFILWA 288
D+WS+GVI YTL+ G PF + E G+Y + F+ +S + +
Sbjct: 329 VDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFY------MSTDCENLLRKF 382
Query: 289 LTVSPKRRPTATDLINDIWI 308
L ++P +R + ++ D W+
Sbjct: 383 LVLNPAKRASLETIMGDKWM 402
>7294217 [D] KOG0588 Serine/threonine protein kinase
Length = 851
Score = 135 bits (341), Expect = 9e-32
Identities = 88/289 (30%), Positives = 149/289 (51%), Gaps = 15/289 (5%)
Query: 31 NKVTGQPSSYVNKSDYIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQ 90
N VT + +V Y KTLG G G+V+ G+ +SV L
Sbjct: 5 NNVTAENCQFVGP--YRLEKTLGKGQTGLVKLGVHCVIGKKVAIKIINREKLS-ESV-LM 60
Query: 91 MLYDELSILQQLNHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFI 150
+ E++I++ ++HP+++ D +E+K+ Y++ + +GGELFD +++KG+ +A
Sbjct: 61 KVEREIAIMKLIDHPHVLGLSDVYENKKYLYLILEHVSGGELFDYLVKKGRLTPKEARKF 120
Query: 151 VKQILQGVQYLHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAG 210
+QI+ + + H +I HRDLKPEN+L K++ + I DFG+A L+ ++ + G
Sbjct: 121 FRQIISALDFCHSHSICHRDLKPENLLLDEKNN---IKIADFGMA-SLQPAGSMLETSCG 176
Query: 211 SMGYVAPEVLTSSGH-GKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVF 269
S Y PEV+ + G+ D+WS GVI Y LL G PF ++ +E+ G VF
Sbjct: 177 SPHYACPEVIRGEKYDGRKADVWSCGVILYALLVGALPFDDDNLRQLLEKVKRG----VF 232
Query: 270 HKPYWNNVSKTAKEFILWALTVSPKRRPTATDLINDIWITSTEKSTTDL 318
H P++ V + + + V+P RR T ++ W+T+ K +L
Sbjct: 233 HIPHF--VPPDCQSLLRGMIEVNPDRRLTLAEINRHPWVTAGGKGELEL 279
>7292679 [G] KOG0599 Phosphorylase kinase gamma subunit
Length = 560
Score = 135 bits (341), Expect = 9e-32
Identities = 82/222 (36%), Positives = 123/222 (54%), Gaps = 13/222 (5%)
Query: 89 LQMLYDELSILQQ-LNHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDA 147
L+ E+SIL+Q + HP I+ +D FES ++V +L GELFD + E
Sbjct: 71 LEATRQEISILRQVMGHPYIIDLQDVFESDAFVFLVFELCPKGELFDYLTSVVTLSEKKT 130
Query: 148 VFIVKQILQGVQYLHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHK 207
I++QI +GV+Y+H ++IVHRDLKPENIL ++ + I DFG AK+L++ +L +
Sbjct: 131 RTIMRQIFEGVEYIHAKSIVHRDLKPENILL---DENHNVKITDFGFAKQLQEGEKLTN- 186
Query: 208 AAGSMGYVAPEVLT------SSGHGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECT 261
G+ GY+APE L S G+ + DIW+ GVI +TLL G PF +
Sbjct: 187 LCGTPGYLAPETLKCNMFEGSPGYSQEVDIWACGVIMFTLLVGCPPFWHRKQMVMLRNIM 246
Query: 262 SGQYPVVFHKPYWNNVSKTAKEFILWALTVSPKRRPTATDLI 303
G+Y F P W ++S+ K+ I L V P +R T +++
Sbjct: 247 EGKYS--FTSPEWADISEDPKDLIRKCLVVDPSQRITVKEVL 286
>CE05780 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 336
Score = 135 bits (340), Expect = 1e-31
Identities = 71/215 (33%), Positives = 120/215 (55%), Gaps = 8/215 (3%)
Query: 94 DELSILQQLNHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQ 153
+E+ +L + H +I+ D F ++ +++IV + A G+L++ I + G+ E DA I Q
Sbjct: 119 NEVEMLSLIQHDHIISIIDAFSTENQYFIVFEHAQYGDLYETIRKNGRIEEPDAAIITLQ 178
Query: 154 ILQGVQYLHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMG 213
+ + YLH+RN+VHRD+KPEN+L ++K + + DFG+A + +++ G+
Sbjct: 179 VASALNYLHERNVVHRDVKPENLLLVDKFS---VKLCDFGLACHILGP---LYRICGTPT 232
Query: 214 YVAPEVLTSSGHGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPY 273
Y APEVL +G+ CDIWS+GV+ Y +L GY+PF A + Q P
Sbjct: 233 YCAPEVLRETGYSTRCDIWSLGVVLYVMLVGYAPFRAPDQTRLFKLIM--QAKPNLDMPE 290
Query: 274 WNNVSKTAKEFILWALTVSPKRRPTATDLINDIWI 308
W +S AK+ + + + +RRP A+ ++ WI
Sbjct: 291 WKGISLKAKDLVSRLMNKTEERRPLASQIMAHPWI 325
>7303211 [T] KOG4717 Serine/threonine protein kinase
Length = 860
Score = 135 bits (340), Expect = 1e-31
Identities = 87/287 (30%), Positives = 141/287 (48%), Gaps = 19/287 (6%)
Query: 46 YIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNHP 105
Y +TLG+G F VV+ AR + +G V L+ E+ ++ + HP
Sbjct: 20 YDLEETLGSGHFAVVKLARHVFTGAKVAVKVVDKTKL--DDVSKAHLFQEVRCMKLVQHP 77
Query: 106 NIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGK-FCEVDAVFIVKQILQGVQYLHQR 164
N+VR + +++ K Y+V +L GG+L+D I++ E A +QIL+ + Y HQ
Sbjct: 78 NVVRLYEVIDTQTKLYLVLELGDGGDLYDYIMKHDSGLSEELARKYFRQILRAITYCHQL 137
Query: 165 NIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSG 224
++VHRDLKPEN+++ K + + DFG + + +L GS+ Y APE+L
Sbjct: 138 HVVHRDLKPENVVFFEKL--GLVKLTDFGFSNKFLPGQKL-ETFCGSLAYSAPEILLGDS 194
Query: 225 HGKPC-DIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKE 283
+ P DIWS+GVI Y L+CG +PF + + +Y V H VS ++
Sbjct: 195 YDAPAVDIWSLGVILYMLVCGQAPFEKANDSETLTMIMDCKYTVPSH------VSTDCRD 248
Query: 284 FILWALTVSPKRRPTATDLINDIWI------TSTEKSTTDLLPEIRK 324
I L PK+R T ++ + W+ ST ++ LP + +
Sbjct: 249 LIASMLVRDPKKRATVEEIASSAWLKPIDEPDSTTSTSEHFLPLVSR 295
>Hs5453966 [T] KOG0583 Serine/threonine protein kinase
Length = 552
Score = 134 bits (338), Expect = 2e-31
Identities = 87/266 (32%), Positives = 131/266 (48%), Gaps = 18/266 (6%)
Query: 46 YIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNHP 105
Y+ G TLG GTFG V+ +G V + + E+ L+ HP
Sbjct: 16 YVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDV-VGKIKREIQNLKLFRHP 74
Query: 106 NIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRN 165
+I++ + F++V + +GGELFD I + G+ E++A + +QIL V Y H+
Sbjct: 75 HIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHRHM 134
Query: 166 IVHRDLKPENIL---YLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTS 222
+VHRDLKPEN+L ++N I DFG++ + D E + + GS Y APEV++
Sbjct: 135 VVHRDLKPENVLLDAHMNAK------IADFGLS-NMMSDGEFLRTSCGSPNYTAPEVISG 187
Query: 223 SGHGKP-CDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTA 281
+ P DIWS GVI Y LLCG PF E ++ G VF+ P + N ++
Sbjct: 188 RLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGG----VFYIPEYLN--RSV 241
Query: 282 KEFILWALTVSPKRRPTATDLINDIW 307
++ L V P +R T D+ W
Sbjct: 242 ATLLMHMLQVDPLKRATIKDIREHEW 267
>7303019 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 913
Score = 134 bits (338), Expect = 2e-31
Identities = 93/320 (29%), Positives = 157/320 (49%), Gaps = 19/320 (5%)
Query: 43 KSDYIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQL 102
KS + + LG G FG+V + + E +S Q + +E+SI++ L
Sbjct: 275 KSRFEIIEELGKGRFGIVYKVQERGQPEQLLAAKVIKCI---KSQDRQKVLEEISIMRAL 331
Query: 103 NHPNIVRFKDWFESKEKFYIVTQLATGGELFDRIL-EKGKFCEVDAVFIVKQILQGVQYL 161
HP +++ FES + +V + TGGELF+R++ + E+D + ++Q+ GV Y+
Sbjct: 332 QHPKLLQLAASFESPREIVMVMEYITGGELFERVVADDFTLTEMDCILFLRQVCDGVAYM 391
Query: 162 HQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLT 221
H +++VH DLKPENI+ ++ +I DFG+A+ L D + G+ ++ PE+++
Sbjct: 392 HGQSVVHLDLKPENIMCHTRTSHQIKII-DFGLAQRL-DTKAPVRVLFGTPEFIPPEIIS 449
Query: 222 SSGHGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTA 281
G D+WS+GVI Y LL G SPF+ ++ T Y + ++ VS+ A
Sbjct: 450 YEPIGFQSDMWSVGVICYVLLSGLSPFMGDTDVETFSNITRADYD--YDDEAFDCVSQEA 507
Query: 282 KEFILWALTVSPKRRPTATDLINDIWIT-------STEKSTTDLLPEIRKGFDARKEFRD 334
K+FI L + R TA + W++ S K TD L K F R++++
Sbjct: 508 KDFISQLLVHRKEDRLTAQQCLASKWLSQRPDDSLSNNKICTDKL----KKFIIRRKWQK 563
Query: 335 AVEIVKLNNRIKKLKVLYEN 354
++ R+ L V N
Sbjct: 564 TGNAIRALGRMANLSVSRRN 583
>7293666 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 576
Score = 134 bits (338), Expect = 2e-31
Identities = 76/217 (35%), Positives = 116/217 (53%), Gaps = 9/217 (4%)
Query: 88 QLQMLYDELSILQQLNHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDA 147
Q + E++I + LNHPNIV+F ++FE + YIV +L + + + E +
Sbjct: 66 QKEKTAQEITIHRSLNHPNIVKFHNYFEDSQNIYIVLELCKKRSMMELHKRRKSITEFEC 125
Query: 148 VFIVKQILQGVQYLHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHK 207
+ + QI+QGV+YLH I+HRDLK N L+LN D + IGDFG+A ++ + E
Sbjct: 126 RYYIYQIIQGVKYLHDNRIIHRDLKLGN-LFLN--DLLHVKIGDFGLATRIEYEGERKKT 182
Query: 208 AAGSMGYVAPEVLTSSGHGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPV 267
G+ Y+APE+LT GH DIWSIG + YTLL G PF ++ + +Y V
Sbjct: 183 LCGTPNYIAPEILTKKGHSFEVDIWSIGCVMYTLLVGQPPFETKTLKDTYSKIKKCEYRV 242
Query: 268 VFHKPYWNNVSKTAKEFILWALTVSPKRRPTATDLIN 304
+ + K A + ++ L +P+ RP L+N
Sbjct: 243 PSY------LRKPAADMVIAMLQPNPESRPAIGQLLN 273
>Hs21361643 [T] KOG4717 Serine/threonine protein kinase
Length = 765
Score = 134 bits (337), Expect = 3e-31
Identities = 84/272 (30%), Positives = 138/272 (49%), Gaps = 15/272 (5%)
Query: 46 YIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNHP 105
Y KTLG G F VV+ AR + +GE ++ L+ E+ ++ + HP
Sbjct: 16 YDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKL--DTLATGHLFQEVRCMKLVQHP 73
Query: 106 NIVRFKDWFESKEKFYIVTQLATGGELFDRIL--EKGKFCEVDAVFIVKQILQGVQYLHQ 163
NIVR + +++ K Y++ +L G++FD I+ E+G ++ + QI+ + Y H+
Sbjct: 74 NIVRLYEVIDTQTKLYLILELGDEGDMFDYIMKHEEGLNEDLPKKYFA-QIVHAISYCHK 132
Query: 164 RNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSS 223
++VHRDLKPEN+++ K + + DFG + + + +L + GS+ Y APE+L
Sbjct: 133 LHVVHRDLKPENVVFFEK--QGLVKLTDFGFSNKFQPGKKLT-TSCGSLAYSAPEILLGD 189
Query: 224 GHGKPC-DIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAK 282
+ P DIWS+GVI + L+CG PF + + +Y V H VSK K
Sbjct: 190 EYDAPAVDIWSLGVILFMLVCGQPPFQEANDSETLTMIMDCKYTVPSH------VSKECK 243
Query: 283 EFILWALTVSPKRRPTATDLINDIWITSTEKS 314
+ I L PKRR + ++ N W+ + S
Sbjct: 244 DLITRMLQRDPKRRASLEEIENHPWLQGVDPS 275
>At4g14580 [T] KOG0583 Serine/threonine protein kinase
Length = 426
Score = 134 bits (337), Expect = 3e-31
Identities = 85/279 (30%), Positives = 140/279 (49%), Gaps = 16/279 (5%)
Query: 32 KVTGQPSSYVNKSDYIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQM 91
K+TG V Y G+ LG+G+F V AR IS+GE ++ ++
Sbjct: 11 KITGT----VLLGKYELGRRLGSGSFAKVHVARSISTGELVAIKIIDKQKTIDSGMEPRI 66
Query: 92 LYDELSILQQLNHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIV 151
+ + ++ + NHPN+++ + +K K Y+V + A GGELF +++ G+ E A
Sbjct: 67 IREIEAMRRLHNHPNVLKIHEVMATKSKIYLVVEYAAGGELFTKLIRFGRLNESAARRYF 126
Query: 152 KQILQGVQYLHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIA--KELKDDNELIHKAA 209
+Q+ + + H+ I HRD+KP+N+L L+K + L + DFG++ E + +N L+H A
Sbjct: 127 QQLASALSFCHRDGIAHRDVKPQNLL-LDKQGN--LKVSDFGLSALPEHRSNNGLLHTAC 183
Query: 210 GSMGYVAPEVLTSSGH-GKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVV 268
G+ Y APEV+ G+ G D WS GV + LL GY PF + + Y
Sbjct: 184 GTPAYTAPEVIAQRGYDGAKADAWSCGVFLFVLLAGYVPFDDANIVAMYRKIHKRDY--- 240
Query: 269 FHKPYWNNVSKTAKEFILWALTVSPKRRPTATDLINDIW 307
P W +SK A+ I L +P+ R + ++ +W
Sbjct: 241 -RFPSW--ISKPARSIIYKLLDPNPETRMSIEAVMGTVW 276
>7300778 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 450
Score = 134 bits (337), Expect = 3e-31
Identities = 85/307 (27%), Positives = 149/307 (47%), Gaps = 19/307 (6%)
Query: 46 YIFGKTLGAGTFGVVRQARCISSGENXXXXXXX---XXXXXGQSVQLQMLYDELSILQQL 102
Y + +G G F +VR RCI N + L E +I L
Sbjct: 12 YELCEVIGKGPFSIVR--RCIHRESNQQFAVKIVDVAKFTASPGLSTADLKREATICHML 69
Query: 103 NHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGK----FCEVDAVFIVKQILQGV 158
HP+IV + + S+ Y+V + G +L ++ + + E A ++QIL+ +
Sbjct: 70 KHPHIVELLETYSSEGMLYMVFEFMEGSDLCFEVVRRAVAGFVYSEAVACHYMRQILEAL 129
Query: 159 QYLHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELI--HKAAGSMGYVA 216
+Y H+ +I+HRD++P L + +P+ +G FG A +L E I H G Y+A
Sbjct: 130 RYCHENDILHRDVRPACALLATVDNSAPVKLGGFGSAIQLPGTRETIETHGRVGCPHYMA 189
Query: 217 PEVLTSSGHGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNN 276
PEV+T +GK CD+W GV+ + LL G PFL G + + + + F P W +
Sbjct: 190 PEVVTRRLYGKGCDVWGAGVMLHVLLSGRLPFL---GSGVRLQQSVARGRLSFEAPEWKS 246
Query: 277 VSKTAKEFILWALTVSPKRRPTATDLINDIWITSTEK----STTDLLPEIRKGFDARKEF 332
+S AK+ ++ L +P R + T++++ WI +K D + E+++ ++AR++
Sbjct: 247 ISANAKDLVMKMLAANPHHRLSITEVLDHPWIRDRDKLQRTHLADTVEELKR-YNARRKL 305
Query: 333 RDAVEIV 339
+ AV+ +
Sbjct: 306 KGAVQAI 312
>At5g45810 [T] KOG0583 Serine/threonine protein kinase
Length = 483
Score = 134 bits (336), Expect = 3e-31
Identities = 89/266 (33%), Positives = 133/266 (49%), Gaps = 16/266 (6%)
Query: 46 YIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNHP 105
Y G+ LG GTF V AR SGE+ +S + + E+SIL+++ HP
Sbjct: 28 YEMGRLLGHGTFAKVYLARNAQSGESVAIKVIDKEKVL-KSGLIAHIKREISILRRVRHP 86
Query: 106 NIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRN 165
NIV+ + +K K Y V + GGELF+++ KG+ E A +Q++ V + H R
Sbjct: 87 NIVQLFEVMATKSKIYFVMEYVKGGELFNKV-AKGRLKEEMARKYFQQLISAVSFCHFRG 145
Query: 166 IVHRDLKPENILYLNKSDDSPLVIGDFG---IAKELKDDNELIHKAAGSMGYVAPEVLTS 222
+ HRDLKPEN+L ++ L + DFG ++ +++ D L H G+ YVAPEVL
Sbjct: 146 VYHRDLKPENLLL---DENGNLKVSDFGLSAVSDQIRQDG-LFHTFCGTPAYVAPEVLAR 201
Query: 223 SGH-GKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTA 281
G+ G DIWS GVI + L+ G+ PF + ++ G F P W V
Sbjct: 202 KGYDGAKVDIWSCGVILFVLMAGFLPFHDRNVMAMYKKIYRGD----FRCPRWFPVE--I 255
Query: 282 KEFILWALTVSPKRRPTATDLINDIW 307
++ L P+RR T D++ W
Sbjct: 256 NRLLIRMLETKPERRFTMPDIMETSW 281
>Hs4506735 [T] KOG0603 Ribosomal protein S6 kinase
Length = 772
Score = 133 bits (334), Expect = 6e-31
Identities = 90/294 (30%), Positives = 138/294 (46%), Gaps = 23/294 (7%)
Query: 52 LGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNHPNIVRFK 111
LG G+F V R+ R SG+ ++ L + Q +HPN+V
Sbjct: 417 LGQGSFSVCRRCRQRQSGQEFAVKILSRRLEANTQREVAAL----RLCQ--SHPNVVNLH 470
Query: 112 DWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQR-NIVHRD 170
+ + Y+V +L GGEL + I +K F E +A I++ ++ V ++H+ +VHRD
Sbjct: 471 EVHHDQLHTYLVLELLRGGELLEHIRKKRHFSESEASQILRSLVSAVSFMHEEAGVVHRD 530
Query: 171 LKPENILYLNKSDDSPLVIGDFGIAK-ELKDDNELIHKAAGSMGYVAPEVLTSSGHGKPC 229
LKPENILY + + +P+ I DFG A+ + + ++ Y APE+L G+ + C
Sbjct: 531 LKPENILYADDTPGAPVKIIDFGFARLRPQSPGVPMQTPCFTLQYAAPELLAQQGYDESC 590
Query: 230 DIWSIGVITYTLLCGYSPFLAESADGFIEE-----CTSGQYPVVFHKPYWNNVSKTAKEF 284
D+WS+GVI Y +L G PF S G + C + W VS+ AKE
Sbjct: 591 DLWSLGVILYMMLSGQVPFQGASGQGGQSQAAEIMCKIREGRFSLDGEAWQGVSEEAKEL 650
Query: 285 ILWALTVSPKRRPTATDLINDIWI------TSTEKSTTDLL----PEIRKGFDA 328
+ LTV P +R L W+ +S T D+L P +R G +A
Sbjct: 651 VRGLLTVDPAKRLKLEGLRGSSWLQDGSARSSPPLRTPDVLESSGPAVRSGLNA 704
Score = 102 bits (255), Expect = 8e-22
Identities = 69/253 (27%), Positives = 127/253 (49%), Gaps = 11/253 (4%)
Query: 50 KTLGAGTFG---VVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNH-P 105
K LG G +G +VR+A +G+ ++ + E S+L+ + P
Sbjct: 37 KVLGTGAYGKVFLVRKAGGHDAGKLYAMKVLRKAALVQRAKTQEHTRTERSVLELVRQAP 96
Query: 106 NIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRN 165
+V F++ K +++ +GGE+F + ++ F E + +I+ +++LH+
Sbjct: 97 FLVTLHYAFQTDAKLHLILDYVSGGEMFTHLYQRQYFKEAEVRVYGGEIVLALEHLHKLG 156
Query: 166 IVHRDLKPENILYLNKSDDSPLVIGDFGIAKE-LKDDNELIHKAAGSMGYVAPEVLTS-S 223
I++RDLK EN+L + +V+ DFG++KE L ++ E G++ Y+APE++ S +
Sbjct: 157 IIYRDLKLENVLL---DSEGHIVLTDFGLSKEFLTEEKERTFSFCGTIEYMAPEIIRSKT 213
Query: 224 GHGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKE 283
GHGK D WS+G++ + LL G SPF E E + + + P+ + A++
Sbjct: 214 GHGKAVDWWSLGILLFELLTGASPFTLEGERNTQAEVS--RRILKCSPPFPPRIGPVAQD 271
Query: 284 FILWALTVSPKRR 296
+ L PK+R
Sbjct: 272 LLQRLLCKDPKKR 284
>ECU03g0980 [T] KOG0583 Serine/threonine protein kinase
Length = 566
Score = 133 bits (334), Expect = 6e-31
Identities = 81/275 (29%), Positives = 136/275 (49%), Gaps = 16/275 (5%)
Query: 46 YIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYD-----ELSILQ 100
Y F K LG G+ V R + SGE G++ ++M D E+ I
Sbjct: 58 YRFVKQLGTGSSSKVVLGRDVRSGEKVAIKIIPRRVNGGETGDMEMRCDQRVFREVIISS 117
Query: 101 QLNHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQY 160
LNHP+I R K++ S ++++ + G +L+D I+ G E + +Q+L + Y
Sbjct: 118 VLNHPHIARLKNFLYSPTHYFLIFEYVKGRQLYDIIISSGPLKEKEGQRYFRQLLSAIDY 177
Query: 161 LHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVL 220
+H+ ++VHRDLK ENIL ++++D+ L+ DFG++ D+ L++ GS+ + APE+L
Sbjct: 178 IHRNSVVHRDLKIENIL-IDENDNVKLI--DFGLS-NFYDNKTLLNTFCGSLYFAAPELL 233
Query: 221 TSSGH-GKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSK 279
+ G D+WS+GV+ Y +LCG PF E G + + + +S+
Sbjct: 234 QGQRYCGPEIDVWSLGVVLYAILCGCVPFDDEDVQGLQAKIMDADF------KFCKTISR 287
Query: 280 TAKEFILWALTVSPKRRPTATDLINDIWITSTEKS 314
A E I + P R + +I W+ +KS
Sbjct: 288 EAMELIRGMIVAQPSSRMGLSQVIGSEWVNKGQKS 322
>Hs4758194 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 372
Score = 132 bits (332), Expect = 1e-30
Identities = 86/262 (32%), Positives = 140/262 (52%), Gaps = 8/262 (3%)
Query: 50 KTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNH-PNIV 108
K LG G F VVRQ S+G+ GQ + ++L+ E+++L+ P ++
Sbjct: 37 KELGRGKFAVVRQCISKSTGQEYAAKFLKKRRR-GQDCRAEILH-EIAVLELAKSCPRVI 94
Query: 109 RFKDWFESKEKFYIVTQLATGGELFDRILEK--GKFCEVDAVFIVKQILQGVQYLHQRNI 166
+ +E+ + ++ + A GGE+F L + E D + ++KQIL+GV YLHQ NI
Sbjct: 95 NLHEVYENTSEIILILEYAAGGEIFSLCLPELAEMVSENDVIRLIKQILEGVYYLHQNNI 154
Query: 167 VHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSGHG 226
VH DLKP+NIL + + I DFG+++++ EL + G+ Y+APE+L
Sbjct: 155 VHLDLKPQNILLSSIYPLGDIKIVDFGMSRKIGHACEL-REIMGTPEYLAPEILNYDPIT 213
Query: 227 KPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKEFIL 286
D+W+IG+I Y LL SPF+ E D Q V + + +++VS+ A +FI
Sbjct: 214 TATDMWNIGIIAYMLLTHTSPFVGE--DNQETYLNISQVNVDYSEETFSSVSQLATDFIQ 271
Query: 287 WALTVSPKRRPTATDLINDIWI 308
L +P++RPTA ++ W+
Sbjct: 272 SLLVKNPEKRPTAEICLSHSWL 293
>7302570 [R] KOG0586 Serine/threonine protein kinase
Length = 702
Score = 132 bits (332), Expect = 1e-30
Identities = 84/265 (31%), Positives = 131/265 (48%), Gaps = 13/265 (4%)
Query: 46 YIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNHP 105
Y KT+G G F VV+ A I + + L + E++IL+ L HP
Sbjct: 41 YELEKTIGKGNFAVVKLATNIVTKTKVAIKIIDKTCLNEE--YLNKTFREIAILKSLRHP 98
Query: 106 NIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRN 165
+I R + ES+ Y+VT+ A GE+FD ++ G+ E +A + Q++ V Y H+R
Sbjct: 99 HITRLYEVMESQSMIYLVTEYAPNGEIFDHLVANGRMKEPEAARVFTQLVSAVHYCHRRG 158
Query: 166 IVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSGH 225
+VHRDLK EN+L L+K D + + DFG + ++ + GS Y APEV +
Sbjct: 159 VVHRDLKAENVL-LDK--DMNIKLADFGFSNHY-EEGATLKTWCGSPPYAAPEVFQGLEY 214
Query: 226 -GKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKEF 284
G DIWS+GV+ Y L+CG PF ++ G++ + F +S+ ++
Sbjct: 215 DGPKSDIWSLGVVLYALVCGALPFDGKTILELKSRVVLGKFRIPFF------MSQECEQL 268
Query: 285 ILWALTVSPKRRPTATDLINDIWIT 309
I L V P RR T +I W++
Sbjct: 269 IRNMLVVEPDRRYTIKQIIKHRWLS 293
>Hs21361133 [R] KOG0586 Serine/threonine protein kinase
Length = 752
Score = 132 bits (331), Expect = 1e-30
Identities = 95/313 (30%), Positives = 146/313 (46%), Gaps = 37/313 (11%)
Query: 45 DYIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNH 104
+Y KT+G G F V+ AR I +G S LQ L+ E+ I++ LNH
Sbjct: 55 NYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTS--LQKLFREVRIMKILNH 112
Query: 105 PNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQ----------- 153
PNIV+ + E+++ Y++ + A+GGE+FD ++ GK E +A +Q
Sbjct: 113 PNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGKMKEKEARSKFRQGCQAGQTIKVQ 172
Query: 154 ------------ILQGVQYLHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDD 201
I+ VQY HQ+ IVHRDLK EN+L D + I DFG + E
Sbjct: 173 VSFDLLSLMFTFIVSAVQYCHQKRIVHRDLKAENLLL---DADMNIKIADFGFSNEFTVG 229
Query: 202 NELIHKAAGSMGYVAPEVLTSSGH-GKPCDIWSIGVITYTLLCGYSPFLAESADGFIEEC 260
+L GS Y APE+ + G D+WS+GVI YTL+ G PF ++ E
Sbjct: 230 GKL-DTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERV 288
Query: 261 TSGQYPVVFHKPYWNNVSKTAKEFILWALTVSPKRRPTATDLINDIWITSTEKSTTDLLP 320
G+Y + F+ +S + + L ++P +R T ++ D WI + + +L P
Sbjct: 289 LRGKYRIPFY------MSTDCENLLKRFLVLNPIKRGTLEQIMKDRWINAGHEE-DELKP 341
Query: 321 EIRKGFDARKEFR 333
+ D + R
Sbjct: 342 FVEPELDISDQKR 354
>YDR477w [T] KOG0583 Serine/threonine protein kinase
Length = 633
Score = 131 bits (330), Expect = 2e-30
Identities = 87/264 (32%), Positives = 137/264 (50%), Gaps = 13/264 (4%)
Query: 45 DYIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNH 104
+Y KTLG G+FG V+ A ++G+ +Q + + E+S L+ L H
Sbjct: 54 NYQIVKTLGEGSFGKVKLAYHTTTGQKVALKIINKKVLAKSDMQGR-IEREISYLRLLRH 112
Query: 105 PNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQR 164
P+I++ D +SK++ +V + A G ELFD I+++ K E +A +QI+ V+Y H+
Sbjct: 113 PHIIKLYDVIKSKDEIIMVIEYA-GNELFDYIVQRDKMSEQEARRFFQQIISAVEYCHRH 171
Query: 165 NIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSG 224
IVHRDLKPEN+L + + I DFG++ + D N + + GS Y APEV++
Sbjct: 172 KIVHRDLKPENLLL---DEHLNVKIADFGLSNIMTDGN-FLKTSCGSPNYAAPEVISGKL 227
Query: 225 HGKP-CDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKE 283
+ P D+WS GVI Y +LC PF ES + ++G Y + +S A
Sbjct: 228 YAGPEVDVWSCGVILYVMLCRRLPFDDESIPVLFKNISNGVYTLP------KFLSPGAAG 281
Query: 284 FILWALTVSPKRRPTATDLINDIW 307
I L V+P R + +++ D W
Sbjct: 282 LIKRMLIVNPLNRISIHEIMQDDW 305
>HsM4506035 [T] KOG0604 MAP kinase-activated protein kinase 2
Length = 471
Score = 131 bits (330), Expect = 2e-30
Identities = 104/334 (31%), Positives = 154/334 (45%), Gaps = 49/334 (14%)
Query: 52 LGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNHPNIVRFK 111
LGAG G VR S+ E V+L M+ HPNIV+
Sbjct: 28 LGAGISGPVRVCVKKSTQERFALKILLDRPKARNEVRLHMMC--------ATHPNIVQII 79
Query: 112 DWFESKEKF----------YIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYL 161
+ F + +F IV ++ GGELF RI + F E A + KQI +++
Sbjct: 80 EVFANSVQFPHESSPRARLLIVMEMMEGGELFHRISQHRHFTEKQASQVTKQIALALRHC 139
Query: 162 HQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVL- 220
H NI HRDLKPEN+L+ + S D+P+ + DFG AK + D + + YVAP+VL
Sbjct: 140 HLLNIAHRDLKPENLLFKDNSLDAPVKLCDFGFAKIDQGD---LMTPQFTPYYVAPQVLE 196
Query: 221 -----------------TSSGHGKPCDIWSIGVITYTLLCGYSPFLAESADGFI-----E 258
T + K CD+WS+GVI Y +LCGY PF ++ I
Sbjct: 197 AQRRHQKEKSGIIPTSPTPYTYNKSCDLWSLGVIIYVMLCGYPPFYSKHHSRTIPKDMRR 256
Query: 259 ECTSGQYPVVFHKPYWNNVSKTAKEFILWALTVSPKRRPTATDLINDIWITSTEKSTTDL 318
+ +G + F + W+ +S+ AK+ + L V P+RR T +++ W+ STE + ++
Sbjct: 257 KIMTGSFE--FPEEEWSQISEMAKDVVRKLLKVKPERRLTIEGVLDHPWLNSTE-ALDNV 313
Query: 319 LPEIRKGFDAR--KEFRDAVEIVKLNNRIKKLKV 350
LP + D + A N RI+ LKV
Sbjct: 314 LPSAQLMMDKAVVAGIQQAHAEQLANMRIQDLKV 347
>Hs5453964 [T] KOG0583 Serine/threonine protein kinase
Length = 550
Score = 131 bits (330), Expect = 2e-30
Identities = 85/266 (31%), Positives = 130/266 (47%), Gaps = 18/266 (6%)
Query: 46 YIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNHP 105
YI G TLG GTFG V+ + +G V + + E+ L+ HP
Sbjct: 18 YILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDV-VGKIRREIQNLKLFRHP 76
Query: 106 NIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRN 165
+I++ + ++V + +GGELFD I + G+ E ++ + +QIL GV Y H+
Sbjct: 77 HIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHM 136
Query: 166 IVHRDLKPENIL---YLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTS 222
+VHRDLKPEN+L ++N I DFG++ + D E + + GS Y APEV++
Sbjct: 137 VVHRDLKPENVLLDAHMNAK------IADFGLS-NMMSDGEFLRTSCGSPNYAAPEVISG 189
Query: 223 SGHGKP-CDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTA 281
+ P DIWS GVI Y LLCG PF + ++ G +F+ P + N S +
Sbjct: 190 RLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDG----IFYTPQYLNPSVIS 245
Query: 282 KEFILWALTVSPKRRPTATDLINDIW 307
+ L V P +R + D+ W
Sbjct: 246 --LLKHMLQVDPMKRASIKDIREHEW 269
>YOR351c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 497
Score = 131 bits (329), Expect = 2e-30
Identities = 84/237 (35%), Positives = 120/237 (50%), Gaps = 26/237 (10%)
Query: 95 ELSILQQLNHPNIVRFKDWF-ESKEKFYIVTQLATGGELFDRILEKG----KFCEVDAVF 149
E IL +L+HPNI++ F + YI L GG+LF L KG E +++
Sbjct: 211 EARILLRLDHPNIIKVYHTFCDRNNHLYIFQDLIPGGDLFS-YLAKGDCLTSMSETESLL 269
Query: 150 IVKQILQGVQYLHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAA 209
IV QILQ + YLH ++IVHRDLK +NIL + +V+ DFGIAK+L + E +H
Sbjct: 270 IVFQILQALNYLHDQDIVHRDLKLDNILLCTPEPCTRIVLADFGIAKDLNSNKERMHTVV 329
Query: 210 GSMGYVAPEV-----------------LTSSGHGKPCDIWSIGVITYTLLCGYSPFLAES 252
G+ Y APEV L G+ CD+WS+GVIT+ +L G SPF +
Sbjct: 330 GTPEYCAPEVGFRANRKAYQSFSRAATLEQRGYDSKCDLWSLGVITHIMLTGISPFYGDG 389
Query: 253 AD-GFIEECTSGQYPVVFHKPYWNNVSKTAKEFILWALTVSPKRRPTATDLINDIWI 308
++ I+ G+ + F W+ VS AK F+ L +R + + IWI
Sbjct: 390 SERSIIQNAKIGK--LNFKLKQWDIVSDNAKSFVKDLLQTDVVKRLNSKQGLKHIWI 444
>CE24761 [D] KOG0580 Serine/threonine protein kinase
Length = 305
Score = 131 bits (329), Expect = 2e-30
Identities = 82/275 (29%), Positives = 130/275 (46%), Gaps = 12/275 (4%)
Query: 34 TGQPSSYVNKSDYIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLY 93
T Q +D+ G+ LG G FG V AR + + V+ Q L
Sbjct: 18 TPQKGGKFTINDFEIGRPLGKGKFGSVYLARTKTGHFHVAIKVLFKSQLISGGVEHQ-LE 76
Query: 94 DELSILQQLNHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQ 153
E+ I LNHPNI++ +F +K Y+V + A GGE++ ++ +F E A + +
Sbjct: 77 REIEIQSHLNHPNIIKLYTYFWDAKKIYLVLEYAPGGEMYKQLTVSKRFSEPTAAKYMYE 136
Query: 154 ILQGVQYLHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMG 213
I + Y H++N++HRD+KPEN+L ++ + L IGDFG + + G+M
Sbjct: 137 IADALSYCHRKNVIHRDIKPENLLIGSQGE---LKIGDFGWSVHAPSNKR--QTMCGTMD 191
Query: 214 YVAPEVLTSSGHGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPY 273
Y+ PE++ + H D+W+IGV+ Y L G PF E + ++ Y
Sbjct: 192 YLPPEMVNGADHSDAVDLWAIGVLCYEFLVGKPPFEHEDQSKTYAAIKAARF------TY 245
Query: 274 WNNVSKTAKEFILWALTVSPKRRPTATDLINDIWI 308
++V K A++ I L V PK R T + WI
Sbjct: 246 PDSVKKGARDLIGRLLVVDPKARCTLEQVKEHYWI 280
>At3g23000 [T] KOG0583 Serine/threonine protein kinase
Length = 429
Score = 131 bits (329), Expect = 2e-30
Identities = 86/296 (29%), Positives = 143/296 (48%), Gaps = 15/296 (5%)
Query: 46 YIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNHP 105
Y G+ LG+G+F V AR I S E ++ +++ + ++ + +HP
Sbjct: 25 YELGRRLGSGSFAKVHLARSIESDELVAVKIIEKKKTIESGMEPRIIREIDAMRRLRHHP 84
Query: 106 NIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRN 165
NI++ + +K K Y+V +LA+GGELF ++L +G+ E A +Q+ +++ HQ
Sbjct: 85 NILKIHEVMATKSKIYLVMELASGGELFSKVLRRGRLPESTARRYFQQLASALRFSHQDG 144
Query: 166 IVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKD-DNELIHKAAGSMGYVAPEVLTSSG 224
+ HRD+KP+N+L + L + DFG++ + N L+H A G+ Y APEV++ G
Sbjct: 145 VAHRDVKPQNLLL---DEQGNLKVSDFGLSALPEHLQNGLLHTACGTPAYTAPEVISRRG 201
Query: 225 H-GKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKE 283
+ G D WS GVI + LL G PF + + Y P W +SK AK
Sbjct: 202 YDGAKADAWSCGVILFVLLVGDVPFDDSNIAAMYRKIHRRDY----RFPSW--ISKQAKS 255
Query: 284 FILWALTVSPKRRPTATDLINDIWITSTEKSTTDLLPEIRKGFDARKEFRDAVEIV 339
I L +P R + ++ W K + + R FD+ E + +V +
Sbjct: 256 IIYQMLDPNPVTRMSIETVMKTNWF----KKSLETSEFHRNVFDSEVEMKSSVNSI 307
>At2g25090 [T] KOG0583 Serine/threonine protein kinase
Length = 469
Score = 131 bits (329), Expect = 2e-30
Identities = 81/275 (29%), Positives = 136/275 (49%), Gaps = 19/275 (6%)
Query: 38 SSYVNKSDYIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELS 97
SS V Y G+ LG G F V IS+G++ + ++ + E++
Sbjct: 7 SSTVLFDKYNIGRLLGTGNFAKVYHGTEISTGDDVAIKVIKKDHVFKRRGMMEQIEREIA 66
Query: 98 ILQQLNHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQG 157
+++ L HPN+V ++ +K+K + V + GGELF+ I GK E A +Q++
Sbjct: 67 VMRLLRHPNVVELREVMATKKKIFFVMEYVNGGELFEMIDRDGKLPEDLARKYFQQLISA 126
Query: 158 VQYLHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDD---------NELIHKA 208
V + H R + HRD+KPEN+L + D L + DFG++ + + ++L+H
Sbjct: 127 VDFCHSRGVFHRDIKPENLLLDGEGD---LKVTDFGLSALMMPEGLGGRRGSSDDLLHTR 183
Query: 209 AGSMGYVAPEVLTSSGH-GKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPV 267
G+ YVAPEVL + G+ G DIWS G++ Y LL G+ PF+ E+ + +
Sbjct: 184 CGTPAYVAPEVLRNKGYDGAMADIWSCGIVLYALLAGFLPFIDENVMTLYTKIFKAECEF 243
Query: 268 VFHKPYWNNVSKTAKEFILWALTVSPKRRPTATDL 302
P W S +KE + L P++R + +++
Sbjct: 244 ----PPW--FSLESKELLSRLLVPDPEQRISMSEI 272
>At1g29230 [T] KOG0583 Serine/threonine protein kinase
Length = 520
Score = 131 bits (329), Expect = 2e-30
Identities = 89/275 (32%), Positives = 136/275 (49%), Gaps = 16/275 (5%)
Query: 37 PSSYVNKSDYIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDEL 96
P + + Y GK LG GTF V A+ I SG+ +S + + E+
Sbjct: 65 PRNNILMGKYELGKLLGHGTFAKVYLAQNIKSGDKVAIKVIDKEKIM-KSGLVAHIKREI 123
Query: 97 SILQQLNHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQ 156
SIL+++ HP IV + +K K Y V + GGELF+ + KG+ E A +Q++
Sbjct: 124 SILRRVRHPYIVHLFEVMATKSKIYFVMEYVGGGELFNTVA-KGRLPEETARRYFQQLIS 182
Query: 157 GVQYLHQRNIVHRDLKPENILYLNKSDDSPLVIGDFG---IAKELKDDNELIHKAAGSMG 213
V + H R + HRDLKPEN+L NK + L + DFG +A++L+ D L H G+
Sbjct: 183 SVSFCHGRGVYHRDLKPENLLLDNKGN---LKVSDFGLSAVAEQLRQDG-LCHTFCGTPA 238
Query: 214 YVAPEVLTSSGH-GKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKP 272
Y+APEVLT G+ D+WS GVI + L+ G+ PF ++ ++ G+ F P
Sbjct: 239 YIAPEVLTRKGYDAAKADVWSCGVILFVLMAGHIPFYDKNIMVMYKKIYKGE----FRCP 294
Query: 273 YWNNVSKTAKEFILWALTVSPKRRPTATDLINDIW 307
W S + L +P R T +++ + W
Sbjct: 295 RW--FSSDLVRLLTRLLDTNPDTRITIPEIMKNRW 327
>CE18967 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD and related
proteins
Length = 1101
Score = 130 bits (328), Expect = 3e-30
Identities = 83/261 (31%), Positives = 133/261 (50%), Gaps = 10/261 (3%)
Query: 50 KTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNHPNIVR 109
+ LG+G FG V +G++ L L E+ IL++++HP +V
Sbjct: 774 EVLGSGQFGTVYGGIHRRNGQHVAVKLIDKLKFPPNKEDL--LRAEVQILEKVDHPGVVH 831
Query: 110 FKDWFESKEKFYIVTQLATGGELFDRIL--EKGKFCEVDAVFIVKQILQGVQYLHQRNIV 167
F E+ ++ ++V + G ++ + IL EKG+ E F+V QIL+ ++YLH NIV
Sbjct: 832 FMQMLETTDRIFVVMEKLKG-DMLEMILSSEKGRLSERTTQFLVAQILEALRYLHHLNIV 890
Query: 168 HRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSGHGK 227
H DLKPENIL + SD + + DFG A+ + + G+ Y+APEVL + G +
Sbjct: 891 HCDLKPENILLNSNSDFPQVKLCDFGFAR-IIGEKSFRRSVVGTPAYLAPEVLRNKGFNR 949
Query: 228 PCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKEFILW 287
D+WS+GVI Y L G PF + ++ + ++ ++ W +S+ A EFI
Sbjct: 950 SLDMWSVGVIVYVSLSGTFPF--NEDEDINDQIQNAEF--MYPPTPWKEISENAIEFING 1005
Query: 288 ALTVSPKRRPTATDLINDIWI 308
L V +R T T + IW+
Sbjct: 1006 LLQVKMSKRYTVTKAQSQIWM 1026
>At5g01810 [T] KOG0583 Serine/threonine protein kinase
Length = 421
Score = 130 bits (328), Expect = 3e-30
Identities = 100/332 (30%), Positives = 160/332 (48%), Gaps = 32/332 (9%)
Query: 46 YIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXX--GQSVQLQMLYDELSILQQLN 103
Y GK LG GTF V AR + +G++ G + Q++ E+S ++ L
Sbjct: 12 YEVGKFLGQGTFAKVYHARHLKTGDSVAIKVIDKERILKVGMTEQIKR---EISAMRLLR 68
Query: 104 HPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQ 163
HPNIV + +K K Y V + GGELF+++ GK E A +Q+++ V + H
Sbjct: 69 HPNIVELHEVMATKSKIYFVMEHVKGGELFNKV-STGKLREDVARKYFQQLVRAVDFCHS 127
Query: 164 RNIVHRDLKPENILYLNKSDDSPLVIGDFGIA--KELKDDNELIHKAAGSMGYVAPEVLT 221
R + HRDLKPEN+L + L I DFG++ + + + L+H G+ YVAPEV++
Sbjct: 128 RGVCHRDLKPENLLL---DEHGNLKISDFGLSALSDSRRQDGLLHTTCGTPAYVAPEVIS 184
Query: 222 SSGH-GKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKT 280
+G+ G D+WS GVI + LL GY PF + ++ G+ V F P W ++
Sbjct: 185 RNGYDGFKADVWSCGVILFVLLAGYLPFRDSNLMELYKKI--GKAEVKF--PNW--LAPG 238
Query: 281 AKEFILWALTVSPKRRPTATDLINDIW--------ITSTEKSTTDLLPEIRKGFDARKEF 332
AK + L +P R + ++ W + + + T++ E A KE
Sbjct: 239 AKRLLKRILDPNPNTRVSTEKIMKSSWFRKGLQEEVKESVEEETEVDAEAEGNASAEKEK 298
Query: 333 R-----DAVEIVKLNNRIKKLKVLYENQDESD 359
+ +A EI+ L+ L L+E +E +
Sbjct: 299 KRCINLNAFEIISLSTGF-DLSGLFEKGEEKE 329
>Hs4826948 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 358
Score = 130 bits (327), Expect = 4e-30
Identities = 87/310 (28%), Positives = 152/310 (48%), Gaps = 19/310 (6%)
Query: 8 SENNSRKPEEPEPVEGHKLTKLFNKVTGQPSSYVNKSDYIFGKTLGAGTFGVVRQARCIS 67
+E++SRK E P L ++ +P Y + D+ T+G GTFG V +
Sbjct: 12 AESDSRKVAEETPDGAPALCPSPEALSPEPPVY-SLQDFDTLATVGTGTFGRVHLVK-EK 69
Query: 68 SGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNHPNIVRFKDWFESKEKFYIVTQLA 127
+ ++ + Q Q +++E S+L++++HP ++R + + Y++ +
Sbjct: 70 TAKHFFALKVMSIPDVIRLKQEQHVHNEKSVLKEVSHPFLIRLFWTWHDERFLYMLMEYV 129
Query: 128 TGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRNIVHRDLKPENILYLNKSDDSPL 187
GGELF + +G+F +F +I+ ++YLH + IV+RDLKPENIL D +
Sbjct: 130 PGGELFSYLRNRGRFSSTTGLFYSAEIICAIEYLHSKEIVYRDLKPENILL---DRDGHI 186
Query: 188 VIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSGHGKPCDIWSIGVITYTLLCGYSP 247
+ DFG AK+L D + G+ Y+APEV+ S GHG+ D W++G++ + +L G+ P
Sbjct: 187 KLTDFGFAKKLVDRTWTL---CGTPEYLAPEVIQSKGHGRAVDWWALGILIFEMLSGFPP 243
Query: 248 FLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKEFILWALTVSPKRR-----PTATDL 302
F ++ G ++ +G+ H + K+ I L V RR A D+
Sbjct: 244 FFDDNPFGIYQKILAGKIDFPRHLDF------HVKDLIKKLLVVDRTRRLGNMKNGANDV 297
Query: 303 INDIWITSTE 312
+ W S +
Sbjct: 298 KHHRWFRSVD 307
>Hs4758016 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 607
Score = 130 bits (327), Expect = 4e-30
Identities = 89/279 (31%), Positives = 137/279 (48%), Gaps = 20/279 (7%)
Query: 46 YIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSV----QLQMLYDELSILQQ 101
Y+ G+ LG G F ARC + + V Q + + +E+ + +
Sbjct: 23 YLKGRLLGKGGF-----ARCYEATDTETGSAYAVKVIPQSRVAKPHQREKILNEIELHRD 77
Query: 102 LNHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYL 161
L H +IVRF FE + YI +L + L + E + + ++QIL G++YL
Sbjct: 78 LQHRHIVRFSHHFEDADNIYIFLELCSRKSLAHIWKARHTLLEPEVRYYLRQILSGLKYL 137
Query: 162 HQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLT 221
HQR I+HRDLK N +++ L +GDFG+A L+ + G+ YVAPEVL
Sbjct: 138 HQRGILHRDLKLGNFFI---TENMELKVGDFGLAARLEPPEQRKKTICGTPNYVAPEVLL 194
Query: 222 SSGHGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTA 281
GHG D+WS+G + YTLLCG PF E+AD ++E V + P ++S A
Sbjct: 195 RQGHGPEADVWSLGCVMYTLLCGSPPF--ETAD--LKETYRCIKQVHYTLP--ASLSLPA 248
Query: 282 KEFILWALTVSPKRRPTATDLINDIWITSTEKSTTDLLP 320
++ + L SP+ RP+ ++ + T+ T D LP
Sbjct: 249 RQLLAAILRASPRDRPSIDQILRHDFF--TKGYTPDRLP 285
>YOR233w [T] KOG0583 Serine/threonine protein kinase
Length = 800
Score = 130 bits (326), Expect = 5e-30
Identities = 83/276 (30%), Positives = 136/276 (49%), Gaps = 13/276 (4%)
Query: 46 YIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQM-----LYDELSILQ 100
YI G TLG G FG V+ +S N +++ +Y E++ L+
Sbjct: 46 YIIGSTLGEGEFGKVKLGWTKASSSNEVPKQVAIKLIRRDTIKKDADKEIKIYREINALK 105
Query: 101 QLNHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQY 160
L HPNI+ ++ ++ + IV + +GGE + I K + E A + Q++ GV Y
Sbjct: 106 HLTHPNIIYLEEVLQNSKYIGIVLEFVSGGEFYKYIQRKRRLKESSACRLFAQLISGVNY 165
Query: 161 LHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPE-- 218
+H + +VHRDLK EN+L L+K ++ LVI DFG E +DNEL+ + GS Y APE
Sbjct: 166 MHYKGLVHRDLKLENLL-LDKHEN--LVITDFGFVNEFFEDNELMKTSCGSPCYAAPELV 222
Query: 219 VLTSSGHGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKP--YWNN 276
V T + + D+WS GVI Y +L GY P+ + + + + Y + P +
Sbjct: 223 VSTKAYEARKADVWSCGVILYAMLAGYLPW-DDDHENPTGDDIARLYKYITQTPLKFPEY 281
Query: 277 VSKTAKEFILWALTVSPKRRPTATDLINDIWITSTE 312
++ ++ + L +P+RR + +W+ E
Sbjct: 282 ITPIPRDLLRRILVPNPRRRINLQTIKRHVWLKPHE 317
>CE06635 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 7160
Score = 130 bits (326), Expect = 5e-30
Identities = 79/265 (29%), Positives = 130/265 (48%), Gaps = 9/265 (3%)
Query: 46 YIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNHP 105
Y + LG G FGVV + ++G N + + + E+ + L HP
Sbjct: 6263 YDIHEELGTGAFGVVHRVTERATGNNFAAKFVMTPHESDK----ETVRKEIQTMSVLRHP 6318
Query: 106 NIVRFKDWFESKEKFYIVTQLATGGELFDRIL-EKGKFCEVDAVFIVKQILQGVQYLHQR 164
+V D FE + ++ + +GGELF+++ E K E +AV ++Q+ +G+ ++H+
Sbjct: 6319 TLVNLHDAFEDDNEMVMIYEFMSGGELFEKVADEHNKMSEDEAVEYMRQVCKGLCHMHEN 6378
Query: 165 NIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSG 224
N VH DLKPENI++ K + L + DFG+ L D + + G+ + APEV
Sbjct: 6379 NYVHLDLKPENIMFTTKRSNE-LKLIDFGLTAHL-DPKQSVKVTTGTAEFAAPEVAEGKP 6436
Query: 225 HGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKEF 284
G D+WS+GV++Y LL G SPF E+ D + S + + ++ +S+ K+F
Sbjct: 6437 VGYYTDMWSVGVLSYILLSGLSPFGGENDDETLRNVKSCDWNM--DDSAFSGISEDGKDF 6494
Query: 285 ILWALTVSPKRRPTATDLINDIWIT 309
I L P R T + W+T
Sbjct: 6495 IRKLLLADPNTRMTIHQALEHPWLT 6519
>CE06634 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 6831
Score = 130 bits (326), Expect = 5e-30
Identities = 79/265 (29%), Positives = 130/265 (48%), Gaps = 9/265 (3%)
Query: 46 YIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNHP 105
Y + LG G FGVV + ++G N + + + E+ + L HP
Sbjct: 5934 YDIHEELGTGAFGVVHRVTERATGNNFAAKFVMTPHESDK----ETVRKEIQTMSVLRHP 5989
Query: 106 NIVRFKDWFESKEKFYIVTQLATGGELFDRIL-EKGKFCEVDAVFIVKQILQGVQYLHQR 164
+V D FE + ++ + +GGELF+++ E K E +AV ++Q+ +G+ ++H+
Sbjct: 5990 TLVNLHDAFEDDNEMVMIYEFMSGGELFEKVADEHNKMSEDEAVEYMRQVCKGLCHMHEN 6049
Query: 165 NIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSG 224
N VH DLKPENI++ K + L + DFG+ L D + + G+ + APEV
Sbjct: 6050 NYVHLDLKPENIMFTTKRSNE-LKLIDFGLTAHL-DPKQSVKVTTGTAEFAAPEVAEGKP 6107
Query: 225 HGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKEF 284
G D+WS+GV++Y LL G SPF E+ D + S + + ++ +S+ K+F
Sbjct: 6108 VGYYTDMWSVGVLSYILLSGLSPFGGENDDETLRNVKSCDWNM--DDSAFSGISEDGKDF 6165
Query: 285 ILWALTVSPKRRPTATDLINDIWIT 309
I L P R T + W+T
Sbjct: 6166 IRKLLLADPNTRMTIHQALEHPWLT 6190
>At4g18700 [T] KOG0583 Serine/threonine protein kinase
Length = 489
Score = 130 bits (326), Expect = 5e-30
Identities = 99/327 (30%), Positives = 155/327 (47%), Gaps = 34/327 (10%)
Query: 46 YIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNHP 105
Y GK LG GTF V AR + + E+ + + + E+SIL+++ HP
Sbjct: 26 YEMGKLLGHGTFAKVYLARNVKTNESVAIKVIDKEKVLKGGL-IAHIKREISILRRVRHP 84
Query: 106 NIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRN 165
NIV+ + +K K Y V + GGELF+++ KG+ E A +Q++ V + H R
Sbjct: 85 NIVQLFEVMATKAKIYFVMEYVRGGELFNKV-AKGRLKEEVARKYFQQLISAVTFCHARG 143
Query: 166 IVHRDLKPENILYLNKSDDSPLVIGDFG---IAKELKDDNELIHKAAGSMGYVAPEVLTS 222
+ HRDLKPEN+L ++ L + DFG ++ +++ D L H G+ YVAPEVL
Sbjct: 144 VYHRDLKPENLLL---DENGNLKVSDFGLSAVSDQIRQDG-LFHTFCGTPAYVAPEVLAR 199
Query: 223 SGH-GKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTA 281
G+ DIWS GVI + L+ GY PF + ++ G+ F P W + T
Sbjct: 200 KGYDAAKVDIWSCGVILFVLMAGYLPFHDRNVMAMYKKIYRGE----FRCPRWFSTELT- 254
Query: 282 KEFILWALTVSPKRRPTATDLINDIWITSTEKSTTDLLPEIRKGFDARKEFRDAVEIVKL 341
+ L +P++R T +++ + W +KGF K + VE KL
Sbjct: 255 -RLLSKLLETNPEKRFTFPEIMENSW--------------FKKGF---KHIKFYVEDDKL 296
Query: 342 NNRIKKLKVLYENQDESDTDIEVNSTD 368
N + L + ESD D + ++
Sbjct: 297 CNVVDD-DELESDSVESDRDSAASESE 322
>7296450 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 769
Score = 130 bits (326), Expect = 5e-30
Identities = 72/230 (31%), Positives = 119/230 (51%), Gaps = 5/230 (2%)
Query: 45 DYIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNH 104
DY LG G F V +ARC+ + ++ G + + E+ I +L H
Sbjct: 13 DYEVQHLLGKGGFATVYKARCLHTHQDVAIKMIDKKLIQGTGLT-NRVRQEVEIHSRLKH 71
Query: 105 PNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGK-FCEVDAVFIVKQILQGVQYLHQ 163
P++++ +F+ Y+V +LA GEL + + F E +A I+KQ++ G+ YLH
Sbjct: 72 PSVLQLYTFFQDANYVYLVLELAHNGELHRYMNHIARPFTETEAASILKQVVAGLLYLHS 131
Query: 164 RNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSS 223
NI+HRD+ N+L S + + I DFG+A +LK +E G+ Y++PEV++ +
Sbjct: 132 HNIMHRDISLSNLLL---SREMHVKIADFGLATQLKRPDERHMTMCGTPNYISPEVVSRT 188
Query: 224 GHGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPY 273
HG P D+WS+G + YTLL G PF ++ + + +Y + H Y
Sbjct: 189 SHGLPADVWSVGCMLYTLLVGRPPFETDAVQSTLNKVVMSEYIMPAHLSY 238
>Hs21237768 [T] KOG0604 MAP kinase-activated protein kinase 2
Length = 473
Score = 129 bits (325), Expect = 6e-30
Identities = 103/334 (30%), Positives = 153/334 (44%), Gaps = 49/334 (14%)
Query: 52 LGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNHPNIVRFK 111
LGAG G VR S+ E V+L M+ HPNIV+
Sbjct: 28 LGAGISGPVRVCVKKSTQERFALKILLDRPKARNEVRLHMMC--------ATHPNIVQII 79
Query: 112 DWFESKEKF----------YIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYL 161
+ F + +F IV ++ GGELF RI + F E A + KQI +++
Sbjct: 80 EVFANSVQFPHESSPRARLLIVMEMMEGGELFHRISQHRHFTEKQASQVTKQIALALRHC 139
Query: 162 HQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVL- 220
H NI HRDLKPEN+L+ + S D+P+ + DFG AK + D + + YVAP+VL
Sbjct: 140 HLLNIAHRDLKPENLLFKDNSLDAPVKLCDFGFAKIDQGD---LMTPQFTPYYVAPQVLE 196
Query: 221 -----------------TSSGHGKPCDIWSIGVITYTLLCGYSPFLAESADGFI-----E 258
T + K CD+WS+GVI Y +LCGY PF ++ I
Sbjct: 197 AQRRHQKEKSGIIPTSPTPYTYNKSCDLWSLGVIIYVMLCGYPPFYSKHHSRTIPKDMRR 256
Query: 259 ECTSGQYPVVFHKPYWNNVSKTAKEFILWALTVSPKRRPTATDLINDIWITSTEKSTTDL 318
+ +G + F + W+ +S+ AK+ + L V P+ R T +++ W+ STE + ++
Sbjct: 257 KIMTGSFE--FPEEEWSQISEMAKDVVRKLLKVKPEERLTIEGVLDHPWLNSTE-ALDNV 313
Query: 319 LPEIRKGFDAR--KEFRDAVEIVKLNNRIKKLKV 350
LP + D + A N RI+ LKV
Sbjct: 314 LPSAQLMMDKAVVAGIQQAHAEQLANMRIQDLKV 347
>Hs21237765 [T] KOG0604 MAP kinase-activated protein kinase 2
Length = 471
Score = 129 bits (325), Expect = 6e-30
Identities = 103/334 (30%), Positives = 153/334 (44%), Gaps = 49/334 (14%)
Query: 52 LGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNHPNIVRFK 111
LGAG G VR S+ E V+L M+ HPNIV+
Sbjct: 28 LGAGISGPVRVCVKKSTQERFALKILLDRPKARNEVRLHMMC--------ATHPNIVQII 79
Query: 112 DWFESKEKF----------YIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYL 161
+ F + +F IV ++ GGELF RI + F E A + KQI +++
Sbjct: 80 EVFANSVQFPHESSPRARLLIVMEMMEGGELFHRISQHRHFTEKQASQVTKQIALALRHC 139
Query: 162 HQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVL- 220
H NI HRDLKPEN+L+ + S D+P+ + DFG AK + D + + YVAP+VL
Sbjct: 140 HLLNIAHRDLKPENLLFKDNSLDAPVKLCDFGFAKIDQGD---LMTPQFTPYYVAPQVLE 196
Query: 221 -----------------TSSGHGKPCDIWSIGVITYTLLCGYSPFLAESADGFI-----E 258
T + K CD+WS+GVI Y +LCGY PF ++ I
Sbjct: 197 AQRRHQKEKSGIIPTSPTPYTYNKSCDLWSLGVIIYVMLCGYPPFYSKHHSRTIPKDMRR 256
Query: 259 ECTSGQYPVVFHKPYWNNVSKTAKEFILWALTVSPKRRPTATDLINDIWITSTEKSTTDL 318
+ +G + F + W+ +S+ AK+ + L V P+ R T +++ W+ STE + ++
Sbjct: 257 KIMTGSFE--FPEEEWSQISEMAKDVVRKLLKVKPEERLTIEGVLDHPWLNSTE-ALDNV 313
Query: 319 LPEIRKGFDAR--KEFRDAVEIVKLNNRIKKLKV 350
LP + D + A N RI+ LKV
Sbjct: 314 LPSAQLMMDKAVVAGIQQAHAEQLANMRIQDLKV 347
>CE26793_1 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 795
Score = 129 bits (325), Expect = 6e-30
Identities = 87/280 (31%), Positives = 138/280 (49%), Gaps = 15/280 (5%)
Query: 36 QPSSYVNKSDYIFG--KTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLY 93
+P S K + F K LG+GT+G V A ++ L +
Sbjct: 63 EPCSPTKKEKHRFEITKKLGSGTYGKVSLAYDHKFDREVAVKLIKKSAIESKA-DLVRIR 121
Query: 94 DELSILQQLNHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQ 153
E+ I+ LNHPNI++ + FE+K+K +V + ++GGEL+D + G E +A I +Q
Sbjct: 122 REIRIMSALNHPNIIQIYEVFENKDKIILVMEYSSGGELYDYVSRCGSLPEAEARRIFRQ 181
Query: 154 ILQGVQYLHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMG 213
I V Y H+ + HRDLK ENIL L++++++ I DFG++ D N L+ GS
Sbjct: 182 ITSAVLYCHKHRVAHRDLKLENIL-LDQNNNAK--IADFGLSNYFADKN-LLTTFCGSPL 237
Query: 214 YVAPEVLTSSGH-GKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKP 272
Y +PE++ + + G D WS+G++ YTL+ G PF + + + G Y
Sbjct: 238 YASPEIINGTPYKGPEVDCWSLGILLYTLVYGSMPFDGRDFNRMVRQIKRGAY------- 290
Query: 273 YWNNVSKTAKEFILWALTVSPKRRPTATDLINDIWITSTE 312
+ TA I L V+P+RR T D+ + W+ E
Sbjct: 291 FEPETPSTASMLIRNMLRVNPERRATIFDIASHWWLNLEE 330
>Hs7661974 [T] KOG0583 Serine/threonine protein kinase
Length = 651
Score = 129 bits (324), Expect = 8e-30
Identities = 78/265 (29%), Positives = 132/265 (49%), Gaps = 14/265 (5%)
Query: 46 YIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNHP 105
Y +T+G G F V+ A I +GE L + E+ L+ L H
Sbjct: 11 YELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTLGSD---LPRIKTEIEALKNLRHQ 67
Query: 106 NIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRN 165
+I + E+ K ++V + GGELFD I+ + + E + + +QI+ V Y+H +
Sbjct: 68 HICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQG 127
Query: 166 IVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNEL-IHKAAGSMGYVAPEVLTSSG 224
HRDLKPEN+L+ + L + DFG+ + K + + + GS+ Y APE++
Sbjct: 128 YAHRDLKPENLLF---DEYHKLKLIDFGLCAKPKGNKDYHLQTCCGSLAYAAPELIQGKS 184
Query: 225 H-GKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKE 283
+ G D+WS+G++ Y L+CG+ PF ++ ++ G+Y V P W +S ++
Sbjct: 185 YLGSEADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYDV----PKW--LSPSSIL 238
Query: 284 FILWALTVSPKRRPTATDLINDIWI 308
+ L V PK+R + +L+N WI
Sbjct: 239 LLQQMLQVDPKKRISMKNLLNHPWI 263
>7290150 [T] KOG0583 Serine/threonine protein kinase
Length = 582
Score = 129 bits (323), Expect = 1e-29
Identities = 86/274 (31%), Positives = 128/274 (46%), Gaps = 14/274 (5%)
Query: 35 GQPSSYVNKSDYIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYD 94
GQP V Y+ G TLG GTFG V+ + V + +
Sbjct: 19 GQP--LVKIGHYLLGATLGTGTFGKVKIGEHQITRVKVAVKILNRQKIKSLDV-VGKIRR 75
Query: 95 ELSILQQLNHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQI 154
E+ L+ HP+I++ + +++ + +GGELFD I++ GK E A +QI
Sbjct: 76 EIQNLKLFRHPHIIKLYQVISTPSDIFMIMEYVSGGELFDYIVKHGKLQEHQARRFFQQI 135
Query: 155 LQGVQYLHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGY 214
+ GV Y H+ IVHRDLKPEN+L + + I DFG++ + D E + + GS Y
Sbjct: 136 ISGVDYCHRHMIVHRDLKPENLLL---DHNMHVKIADFGLSNMML-DGEFLRTSCGSPNY 191
Query: 215 VAPEVLTSSGHGKP-CDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPY 273
APEV++ + P DIWS GVI Y LLCG PF E + SG +P+ +
Sbjct: 192 AAPEVISGKLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFRKIKSGIFPIPEY--- 248
Query: 274 WNNVSKTAKEFILWALTVSPKRRPTATDLINDIW 307
++K + L V P +R ++ W
Sbjct: 249 ---LNKQVVNLVCQMLQVDPLKRANIEEIKKHEW 279
>Hs21359873 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 603
Score = 128 bits (322), Expect = 1e-29
Identities = 76/223 (34%), Positives = 115/223 (51%), Gaps = 9/223 (4%)
Query: 88 QLQMLYDELSILQQLNHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDA 147
Q + + E+SI + L H ++V F +FE + ++V +L L + + E +A
Sbjct: 94 QREKMSMEISIHRSLAHQHVVGFHGFFEDNDFVFVVLELCRRRSLLELHKRRKALTEPEA 153
Query: 148 VFIVKQILQGVQYLHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHK 207
+ ++QI+ G QYLH+ ++HRDLK N L+LN +D + IGDFG+A +++ D E
Sbjct: 154 RYYLRQIVLGCQYLHRNRVIHRDLKLGN-LFLN--EDLEVKIGDFGLATKVEYDGERKKT 210
Query: 208 AAGSMGYVAPEVLTSSGHGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPV 267
G+ Y+APEVL+ GH D+WSIG I YTLL G PF +Y +
Sbjct: 211 LCGTPNYIAPEVLSKKGHSFEVDVWSIGCIMYTLLVGKPPFETSCLKETYLRIKKNEYSI 270
Query: 268 VFHKPYWNNVSKTAKEFILWALTVSPKRRPTATDLINDIWITS 310
H ++ A I L P RPT +L+ND + TS
Sbjct: 271 PKH------INPVAASLIQKMLQTDPTARPTINELLNDEFFTS 307
>Hs14770402 [R] KOG0586 Serine/threonine protein kinase
Length = 926
Score = 128 bits (322), Expect = 1e-29
Identities = 94/310 (30%), Positives = 145/310 (46%), Gaps = 14/310 (4%)
Query: 51 TLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNHPNIVRF 110
TLG G F VV+ R + +V L+ +Y E+ I++ L+HP+I++
Sbjct: 25 TLGKGNFAVVKLGRHRITKTEVAIKIIDKSQL--DAVNLEKIYREVQIMKMLDHPHIIKL 82
Query: 111 KDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRNIVHRD 170
E+K Y+VT+ A GE+FD + G+ E +A QIL V Y H R IVHRD
Sbjct: 83 YQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGRKIVHRD 142
Query: 171 LKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSGH-GKPC 229
LK EN+L N + + I DFG K EL+ GS Y APEV + G
Sbjct: 143 LKAENLLLDNNMN---IKIADFGFGNFFK-SGELLATWCGSPPYAAPEVFEGQQYEGPQL 198
Query: 230 DIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKEFILWAL 289
DIWS+GV+ Y L+CG PF + + G++ + PY+ +S+ + I L
Sbjct: 199 DIWSMGVVLYVLVCGALPFDGPTLPILRQRVLEGRFRI----PYF--MSEDCEHLIRRML 252
Query: 290 TVSPKRRPTATDLINDIW-ITSTEKSTTDLLPEIRKGFDARKEFRDAVEIVKLNNRIKKL 348
+ P +R T + W + L P+ ++ + EF + V + + I +
Sbjct: 253 VLDPSKRLTIAQIKEHKWMLIEVPVQRPVLYPQEQENEPSIGEFNEQVLRLMHSLGIDQQ 312
Query: 349 KVLYENQDES 358
K + Q++S
Sbjct: 313 KTIESLQNKS 322
>Hs13569922 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 628
Score = 128 bits (322), Expect = 1e-29
Identities = 85/264 (32%), Positives = 128/264 (48%), Gaps = 14/264 (5%)
Query: 46 YIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNHP 105
Y F +TLG GT+G V++AR S L + E+ I+ LNHP
Sbjct: 53 YEFLETLGKGTYGKVKKAR--ESSGRLVAIKSIRKDKIKDEQDLMHIRREIEIMSSLNHP 110
Query: 106 NIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRN 165
+I+ + FE+ K IV + A+ G+L+D I E+ + E +A +QI+ V Y HQ
Sbjct: 111 HIIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAVHYCHQNR 170
Query: 166 IVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSGH 225
+VHRDLK ENIL + + I DFG++ L + + GS Y +PE++ +
Sbjct: 171 VVHRDLKLENILL---DANGNIKIADFGLS-NLYHQGKFLQTFCGSPLYASPEIVNGKPY 226
Query: 226 -GKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKEF 284
G D WS+GV+ Y L+ G PF +++ ++G Y KP A
Sbjct: 227 TGPEVDSWSLGVLLYILVHGTMPFDGHDHKILVKQISNGAYREP-PKP------SDACGL 279
Query: 285 ILWALTVSPKRRPTATDLINDIWI 308
I W L V+P RR T D+ + W+
Sbjct: 280 IRWLLMVNPTRRATLEDVASHWWV 303
>At4g40010 [T] KOG0583 Serine/threonine protein kinase
Length = 350
Score = 128 bits (322), Expect = 1e-29
Identities = 87/263 (33%), Positives = 124/263 (47%), Gaps = 16/263 (6%)
Query: 50 KTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNHPNIVR 109
+ LG+G FGV + R ++GE + VQ +++ + L HPNI+R
Sbjct: 8 RDLGSGNFGVAKLVREKANGEFYAVKYIERGLKIDEHVQREIINH-----RDLKHPNIIR 62
Query: 110 FKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRNIVHR 169
FK+ F + IV + A GGELF+RI G+F E + + KQ++ GV Y H I HR
Sbjct: 63 FKEVFVTPTHLAIVMEYAAGGELFERICNAGRFSEDEGRYYFKQLISGVSYCHAMQICHR 122
Query: 170 DLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIH----KAAGSMGYVAPEVLTSSGH 225
DLK EN L L+ S S L I DFG +K + ++H G+ YVAPEVL+ +
Sbjct: 123 DLKLENTL-LDGSPSSHLKICDFGYSK-----SSVLHSQPKSTVGTPAYVAPEVLSRKEY 176
Query: 226 -GKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKEF 284
GK D+WS GV Y +L G PF I V + P + +S K
Sbjct: 177 NGKIADVWSCGVTLYVMLVGAYPFEDPEDPRNIRNTIQRILSVHYTIPDYVRISSECKHL 236
Query: 285 ILWALTVSPKRRPTATDLINDIW 307
+ P +R T ++ W
Sbjct: 237 LSRIFVADPDKRITVPEIEKHPW 259
>7299322 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 434
Score = 128 bits (322), Expect = 1e-29
Identities = 89/304 (29%), Positives = 144/304 (47%), Gaps = 16/304 (5%)
Query: 21 VEGHKLTKLFNKVTGQPSSYVNKSDYIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXX 80
+ H+ KV + + K D I K LG GT+G V+ +G+
Sbjct: 59 MNNHRKKLRQRKVAPELIESILKFDII--KKLGQGTYGKVQLGINKETGQEVAIKTIKKC 116
Query: 81 XXXGQSVQLQMLYDELSILQQLNHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKG 140
++ L + E+ I+ ++HPNI+ + FE++EK +V + A GGEL+D + E+
Sbjct: 117 KIEAEA-DLVRIRREVQIMSSVHHPNIIHIYEVFENREKMVLVMEFAAGGELYDYLSERK 175
Query: 141 KFCEVDAVFIVKQILQGVQYLHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKD 200
E +A I +Q+ V Y H+ I HRDLK ENIL K + I DFG++ + D
Sbjct: 176 VLTEEEARRIFRQVATAVYYCHKHKICHRDLKLENILLDEKGNAK---IADFGLS-NVFD 231
Query: 201 DNELIHKAAGSMGYVAPEVLTSSGH-GKPCDIWSIGVITYTLLCGYSPFLAESADGFIEE 259
D L+ GS Y +PE++ + + G D WS+GV+ YTL+ G PF + +++
Sbjct: 232 DQRLLGTFCGSPLYASPEIVEGTPYQGPEVDCWSLGVLLYTLVYGSMPFDGSNFKRLVKQ 291
Query: 260 CTSGQYPVVFHKPYWNNVSKTAKEFILWALTVSPKRRPTATDLINDIWITSTEK-STTDL 318
+ G Y Y A I LTV P++R + + + W+ + S DL
Sbjct: 292 ISQGDY-------YEPRKPSRASTLIRDMLTVCPRKRASIEQICSHWWVNENDNVSCLDL 344
Query: 319 LPEI 322
++
Sbjct: 345 AEDL 348
>SPAC23C11.16 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 683
Score = 127 bits (320), Expect = 2e-29
Identities = 72/215 (33%), Positives = 119/215 (54%), Gaps = 9/215 (4%)
Query: 92 LYDELSILQQLNHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIV 151
L+ E+ + Q ++HPNIV F D FE Y++ +L L + + ++ + E + +++
Sbjct: 85 LFGEIKVHQSMSHPNIVGFIDCFEDSTNIYLILELCEHKSLMELLRKRKQLTEPEVRYLM 144
Query: 152 KQILQGVQYLHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGS 211
QIL ++Y+H++ ++HRDLK NI+ L++S++ + IGDFG+A L DD E G+
Sbjct: 145 MQILGALKYMHKKRVIHRDLKLGNIM-LDESNN--VKIGDFGLAALLMDDEERKMTICGT 201
Query: 212 MGYVAPEVLTSS--GHGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVF 269
Y+APE+L +S GH D+WS GV+ Y LL G PF + + + Y
Sbjct: 202 PNYIAPEILFNSKEGHSFEVDLWSAGVVMYALLIGKPPFQDKEVKTIYRKIKANSYSF-- 259
Query: 270 HKPYWNNVSKTAKEFILWALTVSPKRRPTATDLIN 304
P ++S AK+ I LT P RP+ D+++
Sbjct: 260 --PSNVDISAEAKDLISSLLTHDPSIRPSIDDIVD 292
>Hs14993776 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 596
Score = 127 bits (319), Expect = 3e-29
Identities = 92/340 (27%), Positives = 160/340 (47%), Gaps = 21/340 (6%)
Query: 15 PEEPEPVEGHKLTKLFNKVTGQPSSYVNKSDYIFGKTLGAGTFGVVRQARCISSGENXXX 74
P P P H++ +L TG SS + + + LG G FG V C+
Sbjct: 261 PPPPAPFP-HRMVELR---TGNVSSEFSMNSK---EALGGGKFGAV--CTCMEKATGLKL 311
Query: 75 XXXXXXXXXGQSVQLQMLYDELSILQQLNHPNIVRFKDWFESKEKFYIVTQLATGGELFD 134
+ ++ +L E+ ++ QLNH N+++ E+ + + + GGELF+
Sbjct: 312 AAKVIKKQTPKDKEMVLL--EIEVMNQLNHRNLIQLYAAIETPHEIVLFMEYIEGGELFE 369
Query: 135 RILEKG-KFCEVDAVFIVKQILQGVQYLHQRNIVHRDLKPENILYLNKSDDSPLVIGDFG 193
RI+++ EVD + V+QI G+ ++H+ ++H DLKPENIL +N + +I DFG
Sbjct: 370 RIVDEDYHLTEVDTMVFVRQICDGILFMHKMRVLHLDLKPENILCVNTTGHLVKII-DFG 428
Query: 194 IAKELKDDNELIHKAAGSMGYVAPEVLTSSGHGKPCDIWSIGVITYTLLCGYSPFLAESA 253
+A+ + NE + G+ +++PEV+ D+WS+GVITY LL G SPFL +
Sbjct: 429 LARRY-NPNEKLKVNFGTPEFLSPEVVNYDQISDKTDMWSMGVITYMLLSGLSPFLGDDD 487
Query: 254 DGFIEECTSGQYPVVFHKPYWNNVSKTAKEFILWALTVSPKRRPTATDLINDIWITSTEK 313
+ SG + F + + VS AK+F+ + + R A + W+ + +
Sbjct: 488 TETLNNVLSGNW--YFDEETFEAVSDEAKDFVSNLIVKDQRARMNAAQCLAHPWLNNLAE 545
Query: 314 STTDLLPEIR-----KGFDARKEFRDAVEIVKLNNRIKKL 348
++ K + ++ ++ V NR KK+
Sbjct: 546 KAKRCNRRLKSQILLKKYLMKRRWKKNFIAVSAANRFKKI 585
>CE28643 [T] KOG0583 Serine/threonine protein kinase
Length = 564
Score = 127 bits (319), Expect = 3e-29
Identities = 81/266 (30%), Positives = 126/266 (46%), Gaps = 18/266 (6%)
Query: 46 YIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQM---LYDELSILQQL 102
YI +TLG GTFG V+ + E + L + + E+ L
Sbjct: 25 YILKETLGVGTFGKVK----VGIHETTQYKVAVKILNRQKIKSLDVVGKIRREIQNLSLF 80
Query: 103 NHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLH 162
HP+I+R + +++ + +GGELFD I++ G+ +A +QI+ GV Y H
Sbjct: 81 RHPHIIRLYQVISTPSDIFMIMEHVSGGELFDYIVKHGRLKTAEARRFFQQIISGVDYCH 140
Query: 163 QRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTS 222
+ +VHRDLKPEN+L + + + I DFG++ + D + + + GS Y APEV++
Sbjct: 141 RHMVVHRDLKPENLLL---DEQNNVKIADFGLS-NIMTDGDFLRTSCGSPNYAAPEVISG 196
Query: 223 SGHGKP-CDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTA 281
+ P D+WS GVI Y LLCG PF E + SG +P + + +
Sbjct: 197 KLYAGPEVDVWSCGVILYALLCGTLPFDDEHVPSLFRKIKSGVFPTP------DFLERPI 250
Query: 282 KEFILWALTVSPKRRPTATDLINDIW 307
+ L V P +R T D+I W
Sbjct: 251 VNLLHHMLCVDPMKRATIKDVIAHEW 276
>CE07458 [T] KOG0583 Serine/threonine protein kinase
Length = 562
Score = 127 bits (319), Expect = 3e-29
Identities = 81/266 (30%), Positives = 126/266 (46%), Gaps = 18/266 (6%)
Query: 46 YIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQM---LYDELSILQQL 102
YI +TLG GTFG V+ + E + L + + E+ L
Sbjct: 25 YILKETLGVGTFGKVK----VGIHETTQYKVAVKILNRQKIKSLDVVGKIRREIQNLSLF 80
Query: 103 NHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLH 162
HP+I+R + +++ + +GGELFD I++ G+ +A +QI+ GV Y H
Sbjct: 81 RHPHIIRLYQVISTPSDIFMIMEHVSGGELFDYIVKHGRLKTAEARRFFQQIISGVDYCH 140
Query: 163 QRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTS 222
+ +VHRDLKPEN+L + + + I DFG++ + D + + + GS Y APEV++
Sbjct: 141 RHMVVHRDLKPENLLL---DEQNNVKIADFGLS-NIMTDGDFLRTSCGSPNYAAPEVISG 196
Query: 223 SGHGKP-CDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTA 281
+ P D+WS GVI Y LLCG PF E + SG +P + + +
Sbjct: 197 KLYAGPEVDVWSCGVILYALLCGTLPFDDEHVPSLFRKIKSGVFPTP------DFLERPI 250
Query: 282 KEFILWALTVSPKRRPTATDLINDIW 307
+ L V P +R T D+I W
Sbjct: 251 VNLLHHMLCVDPMKRATIKDVIAHEW 276
>Hs20545245 [D] KOG0588 Serine/threonine protein kinase
Length = 795
Score = 127 bits (318), Expect = 4e-29
Identities = 87/294 (29%), Positives = 150/294 (50%), Gaps = 15/294 (5%)
Query: 15 PEEPEPVEGHKLTKLFNKVTGQPSSYVNKSDYIFGKTLGAGTFGVVRQARCISSGENXXX 74
PE + V G + + G+ + YV Y KTLG G G+V+ +G+
Sbjct: 22 PERKDEVAGGGGEEEEAEERGRHAQYVGP--YRLEKTLGKGQTGLVKLGVHCITGQKVAI 79
Query: 75 XXXXXXXXXGQSVQLQMLYDELSILQQLNHPNIVRFKDWFESKEKFYIVTQLATGGELFD 134
+SV L + E++IL+ + HP++++ D +E+K+ Y+V + +GGELFD
Sbjct: 80 KIVNREKLS-ESV-LMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFD 137
Query: 135 RILEKGKFCEVDAVFIVKQILQGVQYLHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGI 194
+++KG+ +A +QI+ + + H +I HRDLKPEN+L K++ + I DFG+
Sbjct: 138 YLVKKGRLTPKEARKFFRQIVSALDFCHSYSICHRDLKPENLLLDEKNN---IRIADFGM 194
Query: 195 AKELKDDNELIHKAAGSMGYVAPEVLTSSGH-GKPCDIWSIGVITYTLLCGYSPFLAESA 253
A L+ + L+ + GS Y PEV+ + G+ D+WS GVI + LL G PF ++
Sbjct: 195 A-SLQVGDSLLETSCGSPHYACPEVIKGEKYDGRRADMWSCGVILFALLVGALPFDDDNL 253
Query: 254 DGFIEECTSGQYPVVFHKPYWNNVSKTAKEFILWALTVSPKRRPTATDLINDIW 307
+E+ G VFH P++ + + + + V P++R + + W
Sbjct: 254 RQLLEKVKRG----VFHMPHF--IPPDCQSLLRGMIEVEPEKRLSLEQIQKHPW 301
>Hs15619015 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 351
Score = 127 bits (318), Expect = 4e-29
Identities = 75/231 (32%), Positives = 117/231 (50%), Gaps = 8/231 (3%)
Query: 35 GQPSSYVNKSDYIFG-KTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLY 93
G P+ SD +TLG G+FG V R +G + Q++ +
Sbjct: 32 GNPAQNTASSDQFERLRTLGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKMK-QVEHIL 90
Query: 94 DELSILQQLNHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQ 153
+E ILQ ++ P +V+ + F+ Y+V + GGE+F R+ G+F E A F Q
Sbjct: 91 NEKRILQAIDFPFLVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQRVGRFSEPHACFYAAQ 150
Query: 154 ILQGVQYLHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMG 213
++ VQYLH +++HRDLKPEN+L L + DFG AK +K + G+
Sbjct: 151 VVLAVQYLHSLDLIHRDLKPENLLI---DQQGYLQVTDFGFAKRVKGRTWTL---CGTPE 204
Query: 214 YVAPEVLTSSGHGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQ 264
Y+APE++ S G+ K D W++GV+ Y + G+ PF A+ E+ SG+
Sbjct: 205 YLAPEIILSKGYNKAVDWWALGVLIYEMAVGFPPFYADQPIQIYEKIVSGR 255
>CE27297 [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 476
Score = 127 bits (318), Expect = 4e-29
Identities = 74/239 (30%), Positives = 126/239 (51%), Gaps = 15/239 (6%)
Query: 94 DELSILQQLNHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILE----KGKFCEVDAVF 149
+E+ ++++L+HPNIV DW + Y+V + GGE F ++++ + E +
Sbjct: 221 NEVEVMKKLSHPNIVAIYDWITVAKYSYMVIEYVGGGEFFSKVVDSKYNRMGLGESLGKY 280
Query: 150 IVKQILQGVQYLHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAA 209
Q++ + YLH I HRD+KPENIL +K++ L + DFG+A K+ +
Sbjct: 281 FAFQLIDAILYLHSVGICHRDIKPENILCSDKAERCILKLTDFGMA---KNSVNRMKTRC 337
Query: 210 GSMGYVAPEVLTSSG--HGKPCDIWSIGVITYTLLCGYSPFLAESADGFI-EECTSGQYP 266
G+ Y APE++ + G + DIWS+G + + GY PF E D + E+ +G+
Sbjct: 338 GTPSYNAPEIVANEGVEYTPKVDIWSLGCVLFITFSGYPPFSEEYTDMTMDEQVLTGR-- 395
Query: 267 VVFHKPYWNNVSKTAKEFILWALTVSPKRRPTATDLINDIWITSTEKSTT--DLLPEIR 323
++FH W ++ + I W LTV P RP+A +L++ W+ + T D+L I+
Sbjct: 396 LIFH-AQWRRITVETQNMIKWMLTVEPSNRPSAVELMSTQWMKCADCRTAKQDILKSIK 453
>At2g37840 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 257
Score = 127 bits (318), Expect = 4e-29
Identities = 71/208 (34%), Positives = 111/208 (53%), Gaps = 3/208 (1%)
Query: 45 DYIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNH 104
DY+ G+ +G+G+F VV +AR G + +Q + L E+ IL+++NH
Sbjct: 11 DYLVGRQIGSGSFSVVWEARHRVDGTEVAIKEIAMDRL-NKKLQ-ESLMSEIFILRRINH 68
Query: 105 PNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQR 164
PNI+R D +S K ++V + GG+L + G E A ++Q+ G+Q L
Sbjct: 69 PNIIRLIDMIKSPGKVHLVLEYCKGGDLSVYVQRHGIVPEATAKHFMQQLAAGLQVLRDN 128
Query: 165 NIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSG 224
NI+HRDLKP+N+L +D+ L I DFG A+ L+ L GS Y+APE++
Sbjct: 129 NIIHRDLKPQNLLLSTNENDADLKIADFGFARSLQ-PRGLAETLCGSPLYMAPEIMQLQK 187
Query: 225 HGKPCDIWSIGVITYTLLCGYSPFLAES 252
+ D+WS+G I + L+ G +PF S
Sbjct: 188 YDAKADLWSVGAILFQLVTGRTPFTGNS 215
>7299507 [T] KOG0607 MAP kinase-interacting kinase and related
serine/threonine protein kinases
Length = 1142
Score = 126 bits (317), Expect = 5e-29
Identities = 80/238 (33%), Positives = 116/238 (48%), Gaps = 30/238 (12%)
Query: 104 HPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQ 163
H I++ ++FE EKFY+V + GG L RI E F E +A I+K+I G+ +LH+
Sbjct: 173 HLGILQLIEFFEDDEKFYLVFEKINGGPLLSRIQEHICFSEHEASQIIKEIASGLDFLHK 232
Query: 164 RNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAA--------GSMGYV 215
+ I HRDLKPENIL + P+ I DF + +K ++ AA GS ++
Sbjct: 233 KGIAHRDLKPENILCVKTDSLCPIKICDFDLGSGIKFTTDISSPAATPQLLTPVGSAEFM 292
Query: 216 APEVL-----TSSGHGKPCDIWSIGVITYTLLCGYSPFLAESADG--------------- 255
APEV+ + + K CD+WS+GVI Y LLCGY PF +
Sbjct: 293 APEVVDLFVGEAHYYDKRCDLWSLGVIAYILLCGYPPFSGNCGEDCGWNRGENCRTCQEL 352
Query: 256 FIEECTSGQYPVVFHKPYWNNVSKTAKEFILWALTVSPKRRPTATDLINDIWITSTEK 313
E G + F + W++VS AK+ I L R +A ++N WI E+
Sbjct: 353 LFESIQEGHFS--FPEAEWHDVSDEAKDLISNLLVKKASNRLSAEAVLNHPWIRMCEQ 408
>CE16081 [T] KOG0583 Serine/threonine protein kinase
Length = 334
Score = 126 bits (316), Expect = 7e-29
Identities = 80/264 (30%), Positives = 135/264 (50%), Gaps = 13/264 (4%)
Query: 46 YIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNHP 105
Y GK LGAG F V+ + E ++ +L L E+ ++++NHP
Sbjct: 49 YRLGKELGAGNFSKVKLGVHQLTKEKVAVKIMDKAKMDAKAQKL--LSREIQAMEEMNHP 106
Query: 106 NIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRN 165
NIV+ + E+ + ++V + A+GGEL+ + E+GK E DA + QI+ V ++H RN
Sbjct: 107 NIVKLFEVVETLTRVHLVIEYASGGELYTYVHERGKLTEGDAKPLFAQIVSAVSHMHSRN 166
Query: 166 IVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSGH 225
IVHRD+K EN+++ S + + + DFG + L D +++ GS Y APE+ + +
Sbjct: 167 IVHRDIKAENVMF---SSPNTVKLVDFGFSC-LVDREQMLRTFCGSPPYAAPELFQDTSY 222
Query: 226 -GKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKEF 284
G+ D+W++GV+ + +L G +PF AE+ T+G+Y + + VS A E
Sbjct: 223 AGELVDVWALGVLLFFMLIGVTPFKAETVPDMKVLITAGKYQIP------DYVSLLATEL 276
Query: 285 ILWALTVSPKRRPTATDLINDIWI 308
I L +R + W+
Sbjct: 277 IKSMLKTDTGQRADIDSVKKHFWM 300
>At3g08730 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 465
Score = 126 bits (316), Expect = 7e-29
Identities = 73/212 (34%), Positives = 112/212 (52%), Gaps = 5/212 (2%)
Query: 38 SSYVNKSDYIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELS 97
S V D+ K +G G FG V Q R + E ++ + + E
Sbjct: 126 SGVVGIDDFEVMKVVGKGAFGKVYQVRKKETSEIYAMKVMRKDHIMEKN-HAEYMKAERD 184
Query: 98 ILQQLNHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQG 157
IL +++HP IV+ K F++K + Y+V GG LF ++ +G F E A +I+
Sbjct: 185 ILTKIDHPFIVQLKYSFQTKYRLYLVLDFINGGHLFFQLYHQGLFREDLARVYTAEIVSA 244
Query: 158 VQYLHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAP 217
V +LH++ I+HRDLKPENIL D +++ DFG+AKE ++N + G+ Y+AP
Sbjct: 245 VSHLHEKGIMHRDLKPENIL---MDTDGHVMLTDFGLAKEF-EENTRSNSMCGTTEYMAP 300
Query: 218 EVLTSSGHGKPCDIWSIGVITYTLLCGYSPFL 249
E++ GH K D WS+G++ Y +L G PFL
Sbjct: 301 EIVRGKGHDKAADWWSVGILLYEMLTGKPPFL 332
>YPL141c [T] KOG0583 Serine/threonine protein kinase
Length = 865
Score = 125 bits (315), Expect = 9e-29
Identities = 78/225 (34%), Positives = 118/225 (51%), Gaps = 15/225 (6%)
Query: 36 QPSSYVNKSDYIFGKTLGAGTFGVVRQA--RCISSGENXXXXX--------XXXXXXXGQ 85
Q +V YI G TLG G FG V+ + S+ N
Sbjct: 31 QRRKHVTFGPYILGSTLGEGEFGKVKLGWPKNFSNSSNSTFDFPKQVAIKLIKRDSISND 90
Query: 86 SVQLQMLYDELSILQQLNHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEV 145
+ +Y E++ L+ L+HPNIV+ ++ ++ IV + A GGE + I +K + E+
Sbjct: 91 YRKEVKIYREINALKHLSHPNIVKLEEVLQNSRYIGIVLEYACGGEFYKYIQKKRRLKEM 150
Query: 146 DAVFIVKQILQGVQYLHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELI 205
+A + Q++ GV Y+H + +VHRDLK EN+L L+K+++ LVI DFG E NEL+
Sbjct: 151 NACRLFSQLISGVHYIHSKGLVHRDLKLENLL-LDKNEN--LVITDFGFVNEFCSRNELM 207
Query: 206 HKAAGSMGYVAPEVLTSSG--HGKPCDIWSIGVITYTLLCGYSPF 248
+ GS Y APE++ S+ + DIWS GVI Y +L GY P+
Sbjct: 208 KTSCGSPCYAAPELVISAEPYEARKADIWSCGVILYAILAGYLPW 252
>HsM4826916 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 603
Score = 125 bits (314), Expect = 1e-28
Identities = 75/223 (33%), Positives = 114/223 (50%), Gaps = 9/223 (4%)
Query: 88 QLQMLYDELSILQQLNHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDA 147
Q + + E+SI + L H ++V F +FE + ++V +L L + + E +A
Sbjct: 94 QREKMSMEISIHRSLAHQHVVGFHGFFEDNDFVFVVLELCRRRSLLEPHKRRKALTEPEA 153
Query: 148 VFIVKQILQGVQYLHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHK 207
+ ++QI+ G QYLH+ ++HRDLK N L+LN +D + IGDFG+A +++ D E
Sbjct: 154 RYYLRQIVLGCQYLHRNRVIHRDLKLGN-LFLN--EDLEVKIGDFGLATKVEYDGERKKT 210
Query: 208 AAGSMGYVAPEVLTSSGHGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPV 267
G+ Y+APEVL+ H D+WSIG I YTLL G PF +Y +
Sbjct: 211 LCGTPNYIAPEVLSKKEHSFEVDVWSIGCIMYTLLVGKPPFETSCLKETYLRIKKNEYSI 270
Query: 268 VFHKPYWNNVSKTAKEFILWALTVSPKRRPTATDLINDIWITS 310
H ++ A I L P RPT +L+ND + TS
Sbjct: 271 PKH------INPVAASLIQKMLQTDPTARPTINELLNDEFFTS 307
>CE17284 [T] KOG0583 Serine/threonine protein kinase
Length = 726
Score = 125 bits (314), Expect = 1e-28
Identities = 79/267 (29%), Positives = 136/267 (50%), Gaps = 16/267 (5%)
Query: 46 YIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNHP 105
Y LG+G FG VR A + + + ++Q E+ L+ L+H
Sbjct: 11 YAVHDELGSGGFGKVRLATHLLTNQKVAIKIIDKKQLGHDLPRVQT---EMDALRNLSHQ 67
Query: 106 NIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRN 165
NI R + E+++KF+IV + +GGE+FD I+ K + E +A +Q++ + ++H +
Sbjct: 68 NICRLYHYIETEDKFFIVMEYCSGGEMFDYIVRKERLEESEARHFFRQLVSAIAFVHSQG 127
Query: 166 IVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKD---DNELIHKAAGSMGYVAPEVLTS 222
HRDLKPEN+L ++D L + DFG+ + + D + GS Y APE++
Sbjct: 128 YAHRDLKPENLLL---TEDLHLKLIDFGLCAKTEKGRIDKHNLDTCCGSPAYAAPELIQG 184
Query: 223 SGH-GKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTA 281
+ G D+WS+G++ YTLL G PF ++ ++ SG F++P + +S +
Sbjct: 185 LQYKGNEADVWSMGILLYTLLVGALPFEDDNMQIMYKKIQSG----CFYEPEF--LSPLS 238
Query: 282 KEFILWALTVSPKRRPTATDLINDIWI 308
K+ + L V P+RR + L+ W+
Sbjct: 239 KQLLRAMLQVVPERRISVKKLLEHDWL 265
>Hs20545357 [T] KOG0583 Serine/threonine protein kinase
Length = 436
Score = 125 bits (313), Expect = 2e-28
Identities = 73/220 (33%), Positives = 119/220 (53%), Gaps = 11/220 (5%)
Query: 90 QMLYDELSILQQLNHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVF 149
++L E+S +++L+HPNI+R + E+ K ++V + A GGELF +I +GK E ++
Sbjct: 116 RLLSREISSMEKLHHPNIIRLYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEPESKL 175
Query: 150 IVKQILQGVQYLHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAA 209
I QI+ V+++H+ I+HRDLK EN+ Y + ++ + +GDFG + K E+++
Sbjct: 176 IFSQIVSAVKHMHENQIIHRDLKAENVFY---TSNTCVKVGDFGFSTVSK-KGEMLNTFC 231
Query: 210 GSMGYVAPEVLTSSGH-GKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVV 268
GS Y APE+ + G DIW++GV+ Y ++ G PF AE+ + G Y V
Sbjct: 232 GSPPYAAPELFRDEHYIGIYVDIWALGVLLYFMVTGTMPFRAETVAKLKKSILEGTYSVP 291
Query: 269 FHKPYWNNVSKTAKEFILWALTVSPKRRPTATDLINDIWI 308
H VS+ I L P R ++ND W+
Sbjct: 292 PH------VSEPCHRLIRGVLQQIPTERYGIDCIMNDEWM 325
>CE15473 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 359
Score = 125 bits (313), Expect = 2e-28
Identities = 88/287 (30%), Positives = 133/287 (45%), Gaps = 17/287 (5%)
Query: 50 KTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNHPNIVR 109
KTLG G+FG V + SG N + Q++ +E ILQ ++ P +V
Sbjct: 56 KTLGTGSFGRVMLVKHKQSG-NYYAMKILDKQKVVKLKQVEHTLNEKRILQAIDFPFLVN 114
Query: 110 FKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRNIVHR 169
F+ Y+V + +GGE+F + G+F E + F QI+ +YLH ++++R
Sbjct: 115 MTFSFKDNSNLYMVLEFISGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYR 174
Query: 170 DLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSGHGKPC 229
DLKPEN+L L I DFG AK +K + G+ Y+APE++ S G+ K
Sbjct: 175 DLKPENLLI---DSTGYLKITDFGFAKRVKGRTWTL---CGTPEYLAPEIILSKGYNKAV 228
Query: 230 DIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKEFILWAL 289
D W++GV+ Y + GY PF A+ E+ SG+ V F + N + K + L
Sbjct: 229 DWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGK--VKFPSHFSNELKDLLKNLLQVDL 286
Query: 290 TVS-PKRRPTATDLINDIWITSTE-------KSTTDLLPEIRKGFDA 328
T + D+ N W ST+ K LP+ R DA
Sbjct: 287 TKRYGNLKNGVADIKNHKWFGSTDWIAIYQKKIEAPFLPKCRGPGDA 333
>At3g08720 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 471
Score = 125 bits (313), Expect = 2e-28
Identities = 73/212 (34%), Positives = 112/212 (52%), Gaps = 5/212 (2%)
Query: 38 SSYVNKSDYIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELS 97
S V D+ K +G G FG V Q R + E ++ + + E
Sbjct: 132 SGVVGIEDFEVLKVVGQGAFGKVYQVRKKDTSEIYAMKVMRKDKIVEKN-HAEYMKAERD 190
Query: 98 ILQQLNHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQG 157
IL +++HP IV+ K F++K + Y+V GG LF ++ +G F E A +I+
Sbjct: 191 ILTKIDHPFIVQLKYSFQTKYRLYLVLDFINGGHLFFQLYHQGLFREDLARVYTAEIVSA 250
Query: 158 VQYLHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAP 217
V +LH++ I+HRDLKPENIL D +++ DFG+AKE ++N + G+ Y+AP
Sbjct: 251 VSHLHEKGIMHRDLKPENIL---MDVDGHVMLTDFGLAKEF-EENTRSNSMCGTTEYMAP 306
Query: 218 EVLTSSGHGKPCDIWSIGVITYTLLCGYSPFL 249
E++ GH K D WS+G++ Y +L G PFL
Sbjct: 307 EIVRGKGHDKAADWWSVGILLYEMLTGKPPFL 338
>At1g60940 [T] KOG0583 Serine/threonine protein kinase
Length = 361
Score = 125 bits (313), Expect = 2e-28
Identities = 96/311 (30%), Positives = 142/311 (44%), Gaps = 24/311 (7%)
Query: 46 YIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNHP 105
Y K +GAG FGV R R +S E ++V +++ + L HP
Sbjct: 4 YELVKDIGAGNFGVARLMRVKNSKELVAMKYIERGPKIDENVAREIINH-----RSLRHP 58
Query: 106 NIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRN 165
NI+RFK+ + I + A GGELF+RI G+F E +A + +Q++ GV Y H
Sbjct: 59 NIIRFKEVVLTPTHIAIAMEYAAGGELFERICSAGRFSEDEARYFFQQLISGVSYCHAMQ 118
Query: 166 IVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIH----KAAGSMGYVAPEVLT 221
I HRDLK EN L L+ S L I DFG +K + L+H G+ Y+APEVL+
Sbjct: 119 ICHRDLKLENTL-LDGSPAPRLKICDFGYSK-----SSLLHSMPKSTVGTPAYIAPEVLS 172
Query: 222 SSGH-GKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKT 280
+ GK D+WS GV Y +L G PF + ++ V + P + ++S+
Sbjct: 173 RGEYDGKMADVWSCGVTLYVMLVGAYPFEDQEDPKNFKKTIQRIMAVKYKIPDYVHISQD 232
Query: 281 AKEFILWALTVSPKRRPTATDLINDIWITSTEKSTTDLLPEIRKGFDARKE-----FRDA 335
K + + +R T D+ W K+ L EI + RKE +
Sbjct: 233 CKHLLSRIFVTNSNKRITIGDIKKHPWFL---KNLPRELTEIAQAAYFRKENPTFSLQSV 289
Query: 336 VEIVKLNNRIK 346
EI+K+ K
Sbjct: 290 EEIMKIVEEAK 300
>SPBC4F6.06 [T] KOG0583 Serine/threonine protein kinase
Length = 891
Score = 124 bits (312), Expect = 2e-28
Identities = 96/345 (27%), Positives = 155/345 (44%), Gaps = 47/345 (13%)
Query: 3 KKEPLSENNSRKPEEPEPVEGHKLT-----KLFNKVTGQPSSYVNKSDYIFGKTLGAGTF 57
K P S + +R PV GH + + KV G +Y+ GKT+GAG+
Sbjct: 86 KPLPASPSRTRDHSLRVPVSGHSYSADEKPRERRKVIG---------NYVLGKTIGAGSM 136
Query: 58 GVVRQARCISSGENXX---------------XXXXXXXXXXGQSVQLQMLYD--ELSILQ 100
G V+ A + +GE QS + + + E ++
Sbjct: 137 GKVKVAHHLKTGEQFAIKIVTRLHPDITKAKAAASAEATKAAQSEKNKEIRTVREAALST 196
Query: 101 QLNHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQY 160
L HP I +D + + +Y+V + GG++ D I+ GK E A V+QI + Y
Sbjct: 197 LLRHPYICEARDVYITNSHYYMVFEFVDGGQMLDYIISHGKLKEKQARKFVRQIGSALSY 256
Query: 161 LHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVL 220
LHQ ++VHRDLK ENIL ++K+ D ++ DFG++ + + L GS+ + APE+L
Sbjct: 257 LHQNSVVHRDLKIENIL-ISKTGDIKII--DFGLSNLYRRQSRL-RTFCGSLYFAAPELL 312
Query: 221 TSSGH-GKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSG--QYPVVFHKPYWNNV 277
+ + G D+WS G++ Y L+CG PF ++ + G +YP + +
Sbjct: 313 NAQPYIGPEVDVWSFGIVLYVLVCGKVPFDDQNMSALHAKIKKGTVEYP--------SYL 364
Query: 278 SKTAKEFILWALTVSPKRRPTATDLINDIW-ITSTEKSTTDLLPE 321
S K + L P +R T +++N W I + E PE
Sbjct: 365 SSDCKGLLSRMLVTDPLKRATLEEVLNHPWMIRNYEGPPASFAPE 409
>Hs10835065 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 277
Score = 124 bits (312), Expect = 2e-28
Identities = 71/216 (32%), Positives = 121/216 (55%), Gaps = 11/216 (5%)
Query: 51 TLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNHPNIVR- 109
T+G GTFG V + + ++ + Q Q +++E S+L++++HP ++R
Sbjct: 54 TMGTGTFGRVHLVK-EKTAKHFFALKVMSIPDVIRRKQEQHVHNEKSVLKEVSHPFLIRL 112
Query: 110 FKDWFESKEKF-YIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRNIVH 168
F W E E+F Y++ + GGELF + +G F +F +I+ ++YLH + IV+
Sbjct: 113 FWTWHE--ERFLYMLMEYVPGGELFSYLRNRGHFSSTTGLFYSAEIICAIEYLHSKEIVY 170
Query: 169 RDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSGHGKP 228
RDLKPENIL D + + DFG AK+L D + G+ Y+APEV+ S GHG+
Sbjct: 171 RDLKPENILL---DRDGHIKLTDFGFAKKLVDRTWTL---CGTPEYLAPEVIQSKGHGRA 224
Query: 229 CDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQ 264
D W++G++ + +L G+ PF ++ G ++ +G+
Sbjct: 225 VDWWALGILIFEMLSGFPPFFDDNPFGIYQKILAGK 260
>YPL203w [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 380
Score = 124 bits (311), Expect = 3e-28
Identities = 75/237 (31%), Positives = 119/237 (49%), Gaps = 9/237 (3%)
Query: 45 DYIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNH 104
D+ +TLG G+FG V R + +G Q++ DE +L+ + H
Sbjct: 69 DFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKQQVVKMK-QVEHTNDERRMLKLVEH 127
Query: 105 PNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQR 164
P ++R F+ ++V GGELF + + +F A F +++ ++YLH
Sbjct: 128 PFLIRMWGTFQDARNIFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVILALEYLHAH 187
Query: 165 NIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSG 224
NI++RDLKPENIL + + I DFG AKE++ + G+ Y+APEV+T+
Sbjct: 188 NIIYRDLKPENILL---DRNGHIKITDFGFAKEVQ---TVTWTLCGTPDYIAPEVITTKP 241
Query: 225 HGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQ--YPVVFHKPYWNNVSK 279
+ K D WS+GV+ Y +L GY+PF + E+ G+ YP FH + +SK
Sbjct: 242 YNKSVDWWSLGVLIYEMLAGYTPFYDTTPMKTYEKILQGKVVYPPYFHPDVVDLLSK 298
>CE22877 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 632
Score = 124 bits (311), Expect = 3e-28
Identities = 89/268 (33%), Positives = 125/268 (46%), Gaps = 11/268 (4%)
Query: 43 KSDYIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQL 102
K+ Y GK LG G F + R S+GE Q Q + E+ I + L
Sbjct: 33 KTRYEKGKFLGKGGFAHCYELRNKSTGELFAGKVVPKALLIKQ-YQRDKMAQEVQIHRNL 91
Query: 103 NHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLH 162
H N+V+ +FE K YI +L L + + E +A + QI++GV YLH
Sbjct: 92 QHRNVVKLYHFFEDKSNVYITLELCPRRSLMELHKRRKAVTEPEARYFTYQIVEGVLYLH 151
Query: 163 QRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTS 222
IVHRDLK N L+LN D+ + IGDFG+A D++E G+ Y+APEVL
Sbjct: 152 NLKIVHRDLKLGN-LFLN--DELQVKIGDFGLATTC-DNDERKKTLCGTPNYIAPEVLNK 207
Query: 223 SGHGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAK 282
GH D+W+IG I Y LL G+ PF ++S + + Y + + S A
Sbjct: 208 IGHSFEVDLWAIGCILYILLFGHPPFESKSLEETYSRIKNNNYVIP------TSASAAAS 261
Query: 283 EFILWALTVSPKRRPTATDLINDIWITS 310
+ I L P RRP A + D + S
Sbjct: 262 QLIRVLLDPVPSRRPNARAVCRDHFFKS 289
>CE15475 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 375
Score = 124 bits (311), Expect = 3e-28
Identities = 82/264 (31%), Positives = 126/264 (47%), Gaps = 10/264 (3%)
Query: 50 KTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNHPNIVR 109
KTLG G+FG V + SG N + Q++ +E ILQ ++ P +V
Sbjct: 56 KTLGTGSFGRVMLVKHKQSG-NYYAMKILDKQKVVKLKQVEHTLNEKRILQAIDFPFLVN 114
Query: 110 FKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRNIVHR 169
F+ Y+V + +GGE+F + G+F E + F QI+ +YLH ++++R
Sbjct: 115 MTFSFKDNSNLYMVLEFISGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYR 174
Query: 170 DLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSGHGKPC 229
DLKPEN+L L I DFG AK +K + G+ Y+APE++ S G+ K
Sbjct: 175 DLKPENLLI---DSTGYLKITDFGFAKRVKGRTWTL---CGTPEYLAPEIILSKGYNKAV 228
Query: 230 DIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKEFILWAL 289
D W++GV+ Y + GY PF A+ E+ SG+ V F + N + K + L
Sbjct: 229 DWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGK--VKFPSHFSNELKDLLKNLLQVDL 286
Query: 290 TVS-PKRRPTATDLINDIWITSTE 312
T + D+ N W ST+
Sbjct: 287 TKRYGNLKNGVADIKNHKWFGSTD 310
>YCL024w [T] KOG0583 Serine/threonine protein kinase
Length = 1037
Score = 124 bits (310), Expect = 4e-28
Identities = 84/277 (30%), Positives = 139/277 (49%), Gaps = 16/277 (5%)
Query: 36 QPSSYVNKSDYIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQ-------SVQ 88
+PSS + + G+TLG G+ G V+ A+ +G SV
Sbjct: 13 KPSSTIGP--WKLGETLGFGSTGKVQLAQHERTGHRTAVKVISKSIFNNNGNHSNDDSVL 70
Query: 89 LQMLYDELSILQQLNHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAV 148
+ E+ I++ L+HPN++ D +E+ Y++ + A GELF+ +++ G E +A+
Sbjct: 71 PYNIEREIVIMKLLSHPNVLSLYDVWETNNNLYLILEYAEKGELFNLLVDHGPLPEREAI 130
Query: 149 FIVKQILQGVQYLHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKA 208
+QI+ G+ Y H IVHRDLKPEN+L + I DFG+A L+ D +L+ +
Sbjct: 131 NCFRQIIIGISYCHALGIVHRDLKPENLLL---DSFYNIKIADFGMA-ALQTDADLLETS 186
Query: 209 AGSMGYVAPEVLTSSGH-GKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPV 267
GS Y APE+++ + G D+WS GVI + LL G PF + +G + +
Sbjct: 187 CGSPHYAAPEIVSGLPYEGFASDVWSCGVILFALLTGRLPF--DEENGNVRDLLLKVQKG 244
Query: 268 VFHKPYWNNVSKTAKEFILWALTVSPKRRPTATDLIN 304
F P +S+ A++ I L V P++R D+++
Sbjct: 245 QFEMPNDTEISRDAQDLIGKILVVDPRQRIKIRDILS 281
>CE03584 [T] KOG0607 MAP kinase-interacting kinase and related
serine/threonine protein kinases
Length = 761
Score = 124 bits (310), Expect = 4e-28
Identities = 83/284 (29%), Positives = 133/284 (46%), Gaps = 34/284 (11%)
Query: 52 LGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQL-NHPNIVRF 110
LG+G +G V + I SG G++ + + E++I + +HPNIV+
Sbjct: 207 LGSGAYGSVTTCKSIKSGVEYAVKIVDKQ---GETHSRKRILREVNIFKTCKDHPNIVQL 263
Query: 111 KDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRNIVHRD 170
DWFE + FY+V + GG L IL++ F E +A + K I ++++H R I HRD
Sbjct: 264 LDWFEDETNFYLVMEKMRGGPLLQHILQRKYFTEEEARRVTKDISLALKFMHDRGIAHRD 323
Query: 171 LKPENILYLNKSDDSPLVIGDFGIAKELKDDNEL-----------IHKAAGSMGYVAPEV 219
+KPEN+L + + SP+ + D +A + +E + GS ++APEV
Sbjct: 324 VKPENVLCTDPNHVSPVKLCDLDLASQRPPQHERHPLSQVASEPDLASPVGSAEFMAPEV 383
Query: 220 L-----TSSGHGKPCDIWSIGVITYTLLCGYSPFLAESAD---GF-----IEECTSGQYP 266
+ S + K CD WS+GVI Y +L GY+PF D G+ E+C +
Sbjct: 384 VDAYVGDSLKYDKKCDTWSLGVILYIMLAGYAPFQGMCDDEDCGWSEGKPCEDCQQDLFH 443
Query: 267 VV------FHKPYWNNVSKTAKEFILWALTVSPKRRPTATDLIN 304
+ F + W +S+ AK+ + L P R +N
Sbjct: 444 RIQDGYYEFPEEEWGMISEEAKDLVSNLLKRDPVDRLVTVSFVN 487
>7296128 [T] KOG0583 Serine/threonine protein kinase
Length = 550
Score = 124 bits (310), Expect = 4e-28
Identities = 81/278 (29%), Positives = 138/278 (49%), Gaps = 14/278 (5%)
Query: 46 YIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNHP 105
Y F +G G F V+ A + + + L+ML E++ L+ ++HP
Sbjct: 44 YRFCGDIGRGNFSKVKLAVHQLTRDKVAIKVVDLDRAGLDAKALRMLSSEIATLECVHHP 103
Query: 106 NIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRN 165
NI+R + E+ + Y+VT+ GGEL++ I + G E+ A ++KQ+L V+++H
Sbjct: 104 NILRLFEVVETLGRVYLVTEWIRGGELYNHITQGGPLREIHAAPLLKQLLLAVKHMHSLG 163
Query: 166 IVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDD---NELIHKAAGSMGYVAPEVLTS 222
VHRD+K EN+L L+ + L + DFG + +L + N+ + GS Y APE+ +
Sbjct: 164 YVHRDIKAENVLLLS---EDRLKLADFGFSTQLINGTGANQKLDTFCGSPPYAAPELFSD 220
Query: 223 SGH-GKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTA 281
+ G P D+W++G++ Y ++ G PF A + G G Y + +S
Sbjct: 221 DHYIGAPVDVWALGILLYFMVVGNMPFRAPTIPGLKAAILKGDYLLP------GQLSLPC 274
Query: 282 KEFILWALTVSPKRRPTATDLINDIWITSTEKSTTDLL 319
I L P +RPT D++N ++T K + DL+
Sbjct: 275 IRLIQRILIHIPAQRPTIDDMLNSQFVT-CPKLSADLM 311
>7295426 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 490
Score = 124 bits (310), Expect = 4e-28
Identities = 77/244 (31%), Positives = 120/244 (48%), Gaps = 8/244 (3%)
Query: 19 EPVEGHKLTKLFNKVTGQPSSYVNKSDYIFGKTLGAGTFGVVRQARCISSGENXXXXXXX 78
+ EG + +L + + D+ K LG G +G V Q R ++G +
Sbjct: 50 QDTEGQETIQLCEENVNPGKIKLGPKDFELKKVLGKGGYGKVFQVRK-TAGRDANKYFAM 108
Query: 79 XXXXXGQSVQLQM----LYDELSILQQLNHPNIVRFKDWFESKEKFYIVTQLATGGELFD 134
V Q E +IL+ + HP IV F++ K Y++ + +GGELF
Sbjct: 109 KVLKKASIVTNQKDTAHTRAERNILEAVKHPFIVELVYAFQTDGKLYLILEYLSGGELFM 168
Query: 135 RILEKGKFCEVDAVFIVKQILQGVQYLHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGI 194
+ +G F E F + +I+ + +LH+ I++RDLKPENIL + + DFG+
Sbjct: 169 HLEREGIFLEDTTCFYLSEIILALGHLHKLGIIYRDLKPENILL---DAQGHVKLTDFGL 225
Query: 195 AKELKDDNELIHKAAGSMGYVAPEVLTSSGHGKPCDIWSIGVITYTLLCGYSPFLAESAD 254
KE + + H G++ Y+APE+LT SGHGK D WS+G + + +L G PF AE+
Sbjct: 226 CKEHIQEGIVTHTFCGTIEYMAPEILTRSGHGKAVDWWSLGALMFDMLTGVPPFTAENRK 285
Query: 255 GFIE 258
IE
Sbjct: 286 KTIE 289
>Hs4506055 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 351
Score = 123 bits (309), Expect = 5e-28
Identities = 81/267 (30%), Positives = 131/267 (48%), Gaps = 16/267 (5%)
Query: 50 KTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNHPNIVR 109
KTLG G+FG V + +G N + Q++ +E ILQ +N P +V+
Sbjct: 48 KTLGTGSFGRVMLVKHKETG-NHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVK 106
Query: 110 FKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRNIVHR 169
+ F+ Y+V + GGE+F + G+F E A F QI+ +YLH ++++R
Sbjct: 107 LEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYR 166
Query: 170 DLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSGHGKPC 229
DLKPEN+L + + DFG AK +K + G+ Y+APE++ S G+ K
Sbjct: 167 DLKPENLLI---DQQGYIQVTDFGFAKRVKGRTWTL---CGTPEYLAPEIILSKGYNKAV 220
Query: 230 DIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKEFILWAL 289
D W++GV+ Y + GY PF A+ E+ SG+ V F + +++ + + L
Sbjct: 221 DWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGK--VRFPSHFSSDLKDLLRNLLQVDL 278
Query: 290 TVSPKRRPTATDLINDI----WITSTE 312
T KR + +NDI W +T+
Sbjct: 279 T---KRFGNLKNGVNDIKNHKWFATTD 302
>CE02377 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 1211
Score = 123 bits (309), Expect = 5e-28
Identities = 97/320 (30%), Positives = 157/320 (48%), Gaps = 27/320 (8%)
Query: 46 YIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNHP 105
Y K LG G FG V C+ E ++ + ++ E+SIL QL HP
Sbjct: 45 YQVTKLLGDGKFGKVY---CVIEKETGKEFAAKFIKIRKEADRAEV-EREVSILTQLRHP 100
Query: 106 NIVRFKD-WFESKEKFYIVTQLATGGELFDRILEKGK-FCEVDAVFIVKQILQGVQYLHQ 163
I + D ++ + ++ ++ GGELFDR+ E+ E+ V I+ Q+ + + Y+H+
Sbjct: 101 RIAQIYDAFYTTTNDVVLIMEIVRGGELFDRVAEESYVLSELAVVMIICQLCEAIDYIHK 160
Query: 164 RNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSS 223
+NI+H D+KPENI+ ++ + + +I DFG+A+ EL + A G+ + APEV+
Sbjct: 161 QNILHLDVKPENIMCVSLTGNRIKLI-DFGLARHYDGTQELKYMA-GTPEFAAPEVIKFE 218
Query: 224 GHGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKE 283
D+WSIGVITY LL GYSPFL D E + + V ++ V++ AK+
Sbjct: 219 KLDYHTDMWSIGVITYILLSGYSPFL---GDNLGETYCNVEKGVWEFTEEFDTVTEEAKD 275
Query: 284 FILWALTVSPKRRPTATDLINDIWI----------TSTEK----STTDLLPEIRKGFDAR 329
F+ L +R + + WI T EK T D +R ++AR
Sbjct: 276 FVTKLLVYDQSKRMLPHECLQHPWIAKHRQKAACNTILEKPLNAPTLDNKQIMR--YNAR 333
Query: 330 KEFRDAVEIVKLNNRIKKLK 349
++FR + VK + +L+
Sbjct: 334 RKFRRMIIYVKFLIEMNRLR 353
>At4g33950 [T] KOG0583 Serine/threonine protein kinase
Length = 357
Score = 123 bits (309), Expect = 5e-28
Identities = 89/271 (32%), Positives = 129/271 (46%), Gaps = 24/271 (8%)
Query: 46 YIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNHP 105
Y K +G+G FGV R R S E ++V+ +++ + L HP
Sbjct: 21 YELVKDIGSGNFGVARLMRDKQSNELVAVKYIERGEKIDENVKREIINH-----RSLRHP 75
Query: 106 NIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRN 165
NIVRFK+ + IV + A+GGELF+RI G+F E +A F +Q++ GV Y H
Sbjct: 76 NIVRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLISGVSYCHAMQ 135
Query: 166 IVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIH----KAAGSMGYVAPEVLT 221
+ HRDLK EN L L+ S L I DFG +K + ++H G+ Y+APEVL
Sbjct: 136 VCHRDLKLENTL-LDGSPAPRLKICDFGYSK-----SSVLHSQPKSTVGTPAYIAPEVLL 189
Query: 222 SSGH-GKPCDIWSIGVITYTLLCGYSPFL-AESADGF---IEECTSGQYPVVFHKPYWNN 276
+ GK D+WS GV Y +L G PF E F I + QY + P + +
Sbjct: 190 KKEYDGKVADVWSCGVTLYVMLVGAYPFEDPEEPKNFRKTIHRILNVQYAI----PDYVH 245
Query: 277 VSKTAKEFILWALTVSPKRRPTATDLINDIW 307
+S + I P +R + ++ N W
Sbjct: 246 ISPECRHLISRIFVADPAKRISIPEIRNHEW 276
>SPBC21.06c [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 1062
Score = 123 bits (308), Expect = 6e-28
Identities = 86/309 (27%), Positives = 140/309 (44%), Gaps = 18/309 (5%)
Query: 41 VNKSDYIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQ 100
+ S G LG G FG V + I +GE L ++ E+ +L+
Sbjct: 4 IQASSITLGDCLGKGAFGAVYRGLNIKNGETVAVKKVKLSKMLKSD--LSVIKMEIDLLK 61
Query: 101 QLNHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQY 160
L+HPNIV+++ +++ + I+ + G L GK E Q+LQG+ Y
Sbjct: 62 NLDHPNIVKYRGSYQTNDSLCIILEYCENGSLRSICKNFGKIPENLVALYTFQVLQGLLY 121
Query: 161 LHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVL 220
LH + ++HRD+K NIL + D + + DFG+A ++ + H GS ++APEV+
Sbjct: 122 LHNQGVIHRDIKGANIL---TTKDGTIKLADFGVATKINALED--HSVVGSPYWMAPEVI 176
Query: 221 TSSGHGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVV--FHKPYWNNVS 278
G DIWS+G LL G P+ + + TS + +V H P +N+S
Sbjct: 177 ELVGATTASDIWSVGCTVIELLDGNPPY-------YDLDPTSALFRMVKDEHPPLPSNIS 229
Query: 279 KTAKEFILWALTVSPKRRPTATDLINDIWITSTEKST--TDLLPEIRKGFDARKEFRDAV 336
AK F++ P R L+ W+ + S+ +D + E++K + KE
Sbjct: 230 SAAKSFLMQCFQKDPNLRIKTRKLLKHPWVIMNQTSSKFSDAIDEVQKYNERVKESTLTA 289
Query: 337 EIVKLNNRI 345
I +NRI
Sbjct: 290 IIEPTSNRI 298
>CE07285 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 615
Score = 123 bits (308), Expect = 6e-28
Identities = 81/231 (35%), Positives = 116/231 (50%), Gaps = 10/231 (4%)
Query: 85 QSVQLQMLYDELSILQQLNHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCE 144
+S + L E+ I +QL+H NIV+F +FE + Y +L + L + ++G E
Sbjct: 73 KSTAREKLTREVEIHRQLSHRNIVQFHHFFEDSQNVYFTLELCSKNSLMELNKQRGPLTE 132
Query: 145 VDAVFIVKQILQGVQYLHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNEL 204
+A F Q+ +GV++LH I+HRDLK N L+LN + + IGDFG+A + NE
Sbjct: 133 HEARFYTIQVAEGVKHLHNLQIIHRDLKLGN-LFLN--EHLQVKIGDFGLA-TFCEKNEK 188
Query: 205 IHKAAGSMGYVAPEVLTSSGHGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQ 264
G+ Y+APEVL +GH DIW+IG I Y LL G PF + +
Sbjct: 189 KMTRGGTPNYIAPEVLNETGHAFEVDIWAIGCILYVLLFGSPPFESRRVQETYVRIKNND 248
Query: 265 YPVVFHKPYWNNVSKTAKEFILWALTVSPKRRPTATDLINDIWITSTEKST 315
Y V N S TA I L P RRPTA ++ D + +T + T
Sbjct: 249 YVVP------ENASPTANRLIRSLLDPVPDRRPTAEAVLLDQFFKTTIEPT 293
>At5g08590 [T] KOG0583 Serine/threonine protein kinase
Length = 353
Score = 123 bits (308), Expect = 6e-28
Identities = 85/263 (32%), Positives = 126/263 (47%), Gaps = 16/263 (6%)
Query: 50 KTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNHPNIVR 109
K LGAG FGV R R + E ++V +++ + L HPNI+R
Sbjct: 8 KDLGAGNFGVARLLRHKDTKELVAMKYIERGRKIDENVAREIINH-----RSLKHPNIIR 62
Query: 110 FKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRNIVHR 169
FK+ + IV + A+GGELFDRI G+F E +A + +Q++ GV Y H I HR
Sbjct: 63 FKEVILTPTHLAIVMEYASGGELFDRICTAGRFSEAEARYFFQQLICGVDYCHSLQICHR 122
Query: 170 DLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIH----KAAGSMGYVAPEVLTSSGH 225
DLK EN L L+ S L I DFG +K + ++H G+ Y+APEVL+ +
Sbjct: 123 DLKLENTL-LDGSPAPLLKICDFGYSK-----SSILHSRPKSTVGTPAYIAPEVLSRREY 176
Query: 226 -GKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKEF 284
GK D+WS GV Y +L G PF + + V + P + ++S+ K
Sbjct: 177 DGKHADVWSCGVTLYVMLVGAYPFEDPNDPKNFRKTIQRIMAVQYKIPDYVHISQECKHL 236
Query: 285 ILWALTVSPKRRPTATDLINDIW 307
+ + +R T ++ N W
Sbjct: 237 LSRIFVTNSAKRITLKEIKNHPW 259
>CE28479 [T] KOG0583 Serine/threonine protein kinase
Length = 822
Score = 122 bits (307), Expect = 8e-28
Identities = 83/264 (31%), Positives = 134/264 (50%), Gaps = 13/264 (4%)
Query: 46 YIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNHP 105
Y G+ +G G F VR AR + ++ L L E+ I++ ++HP
Sbjct: 16 YDVGRAIGKGNFATVRIARHKIAKTKVAIKSIDVSALDREN--LIKLEREVKIVKVIDHP 73
Query: 106 NIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRN 165
+IV+ + YIV++ + GEL++ ++EKG+ E A + V YLH +
Sbjct: 74 HIVKSYEIMRVDNMLYIVSEYCSSGELYETLIEKGRVAENVARKWFSETASAVAYLHSQG 133
Query: 166 IVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSGH 225
IVHRDLK ENIL L K+ + ++ DFG + + ++L++ GS Y APE+L + +
Sbjct: 134 IVHRDLKAENIL-LGKNSNIKII--DFGFS-NFQTGDQLLNTWCGSPPYAAPELLLGNSY 189
Query: 226 -GKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKEF 284
G DIWS+GV+ Y L+ G PF ++S + SG + PYW VS +F
Sbjct: 190 DGMKADIWSMGVLLYILVAGGFPFPSDSVNKLKRSVLSGLVKI----PYW--VSVECADF 243
Query: 285 ILWALTVSPKRRPTATDLINDIWI 308
I L ++P +R T +++ W+
Sbjct: 244 IRKMLVLNPGKRYTIQNVLQHRWM 267
>At5g57630 [T] KOG0583 Serine/threonine protein kinase
Length = 412
Score = 122 bits (307), Expect = 8e-28
Identities = 92/322 (28%), Positives = 151/322 (46%), Gaps = 23/322 (7%)
Query: 46 YIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNHP 105
Y G+T+G G F V+ ++G + ++ Q+ E+ ++ LNHP
Sbjct: 12 YEIGRTIGEGNFAKVKLGYDTTNGTYVAVKIIDKALVIQKGLESQVKR-EIRTMKLLNHP 70
Query: 106 NIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRN 165
NIV+ + +K K IV + +GG+L DR L + K E DA + +Q++ V Y H R
Sbjct: 71 NIVQIHEVIGTKTKICIVMEYVSGGQLSDR-LGRQKMKESDARKLFQQLIDAVDYCHNRG 129
Query: 166 IVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSGH 225
+ HRDLKP+N+L +K + L + DFG++ K +++ A GS Y+APE++ + G+
Sbjct: 130 VYHRDLKPQNLLLDSKGN---LKVSDFGLSAVPK-SGDMLSTACGSPCYIAPELIMNKGY 185
Query: 226 -GKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKEF 284
G D+WS GVI + LL GY PF + ++ Y + + K
Sbjct: 186 SGAAVDVWSCGVILFELLAGYPPFDDHTLPVLYKKILRADY------TFPPGFTGEQKRL 239
Query: 285 ILWALTVSPKRRPTATD-LINDIWIT--------STEKSTTDLLPEIRKGFDARKEFRDA 335
I L +P R T + +I D W S D + EI A F +A
Sbjct: 240 IFNILDPNPLSRITLAEIIIKDSWFKIGYTPVYHQLSDSIKDNVAEINAA-TASSNFINA 298
Query: 336 VEIVKLNNRIKKLKVLYENQDE 357
+I+ +++ + + EN D+
Sbjct: 299 FQIIAMSSDLDLSGLFEENDDK 320
>At3g50500 [T] KOG0583 Serine/threonine protein kinase
Length = 362
Score = 122 bits (307), Expect = 8e-28
Identities = 90/285 (31%), Positives = 130/285 (45%), Gaps = 18/285 (6%)
Query: 46 YIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNHP 105
Y F K +G+G FGV R + E ++VQ +++ + L HP
Sbjct: 23 YDFVKDIGSGNFGVARLMTDRVTKELVAVKYIERGEKIDENVQREIINH-----RSLRHP 77
Query: 106 NIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRN 165
NIVRFK+ + IV + A GGEL++RI G+F E +A F +Q++ GV Y H
Sbjct: 78 NIVRFKEVILTPSHLAIVMEYAAGGELYERICNAGRFSEDEARFFFQQLISGVSYCHAMQ 137
Query: 166 IVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIH----KAAGSMGYVAPEVLT 221
I HRDLK EN L L+ S L I DFG +K + ++H G+ Y+APE+L
Sbjct: 138 ICHRDLKLENTL-LDGSPAPRLKICDFGYSK-----SSVLHSQPKSTVGTPAYIAPEILL 191
Query: 222 SSGH-GKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKT 280
+ GK D+WS GV Y +L G PF + V + P ++S
Sbjct: 192 RQEYDGKLADVWSCGVTLYVMLVGAYPFEDPQEPRDYRKTIQRILSVTYSIPEDLHLSPE 251
Query: 281 AKEFILWALTVSPKRRPTATDLINDIWITSTEKSTTDLLPEIRKG 325
+ I P R T ++ +D W + DL+ E R G
Sbjct: 252 CRHLISRIFVADPATRITIPEITSDKWF--LKNLPGDLMDENRMG 294
>At5g58380 [T] KOG0583 Serine/threonine protein kinase
Length = 464
Score = 122 bits (306), Expect = 1e-27
Identities = 72/216 (33%), Positives = 113/216 (51%), Gaps = 10/216 (4%)
Query: 36 QPSSYVNKSDYIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDE 95
+PS +K D G+ LG GTF V R I + ++ + ++ + E
Sbjct: 4 KPSVLTDKYDV--GRLLGQGTFAKVYYGRSILTNQSVAIKMIDKEKVMKVGL-IEQIKRE 60
Query: 96 LSILQQLNHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQIL 155
+S+++ HPN+V + +K + Y V + GGELF+++ KGK + A Q++
Sbjct: 61 ISVMRIARHPNVVELYEVMATKTRIYFVMEYCKGGELFNKV-AKGKLRDDVAWKYFYQLI 119
Query: 156 QGVQYLHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIA--KELKDDNELIHKAAGSMG 213
V + H R + HRD+KPEN+L D+ L + DFG++ + K + L+H G+
Sbjct: 120 NAVDFCHSREVYHRDIKPENLLL---DDNENLKVSDFGLSALADCKRQDGLLHTTCGTPA 176
Query: 214 YVAPEVLTSSGH-GKPCDIWSIGVITYTLLCGYSPF 248
YVAPEV+ G+ G DIWS GV+ + LL GY PF
Sbjct: 177 YVAPEVINRKGYDGTKADIWSCGVVLFVLLAGYLPF 212
>At5g04510 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 488
Score = 122 bits (306), Expect = 1e-27
Identities = 79/273 (28%), Positives = 125/273 (44%), Gaps = 20/273 (7%)
Query: 37 PSSYVNKSDYIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDEL 96
P D+ FGK G G++ V +A+ +G ++ + + +
Sbjct: 32 PQENFTSHDFEFGKIYGVGSYSKVVRAKKKETGTVYALKIMDKKFITKENKTAYVKLERI 91
Query: 97 SILQQLNHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQ 156
+L QL HP I++ F+ Y+ + GGELFD+I KG+ E +A F +++
Sbjct: 92 -VLDQLEHPGIIKLYFTFQDTSSLYMALESCEGGELFDQITRKGRLSEDEARFYTAEVVD 150
Query: 157 GVQYLHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAA------- 209
++Y+H ++HRD+KPEN+L + D + I DFG K ++D + A
Sbjct: 151 ALEYIHSMGLIHRDIKPENLLL---TSDGHIKIADFGSVKPMQDSQITVLPNAASDDKAC 207
Query: 210 ---GSMGYVAPEVLTSSGHGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYP 266
G+ YV PEVL SS D+W++G Y +L G SPF S E Q
Sbjct: 208 TFVGTAAYVPPEVLNSSPATFGNDLWALGCTLYQMLSGTSPFKDAS------EWLIFQRI 261
Query: 267 VVFHKPYWNNVSKTAKEFILWALTVSPKRRPTA 299
+ + N+ S+ A++ I L P RRP A
Sbjct: 262 IARDIKFPNHFSEAARDLIDRLLDTEPSRRPGA 294
>At3g61960 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 648
Score = 122 bits (306), Expect = 1e-27
Identities = 69/204 (33%), Positives = 110/204 (53%), Gaps = 3/204 (1%)
Query: 45 DYIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNH 104
DY G +G+G+F VV A+ SSG + L E+SIL ++H
Sbjct: 9 DYALGPRIGSGSFAVVWLAKHRSSGLEVAVKEIDKKLLSPKV--RDNLLKEISILSTIDH 66
Query: 105 PNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQR 164
PNI+RF + E+ ++ ++V + +GG+L I GK E A ++Q+ G+Q L ++
Sbjct: 67 PNIIRFYEAIETGDRIFLVLEYCSGGDLAGYINRHGKVPEAVAKHFMRQLALGLQVLQEK 126
Query: 165 NIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSG 224
+ +HRDLKP+N+L +K L IGDFG A+ L ++ + GS Y+APE++ +
Sbjct: 127 HFIHRDLKPQNLLLSSKEVTPLLKIGDFGFARSLTPES-MAETFCGSPLYMAPEIIRNQK 185
Query: 225 HGKPCDIWSIGVITYTLLCGYSPF 248
+ D+WS G I + L+ G PF
Sbjct: 186 YDAKADLWSAGAILFQLVTGKPPF 209
>At1g09000 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 666
Score = 122 bits (306), Expect = 1e-27
Identities = 95/338 (28%), Positives = 158/338 (46%), Gaps = 35/338 (10%)
Query: 6 PLSENNSRKPEEPEP-VEGHKLT------KLFNKVTGQPSSYVNKSD------YIFGKTL 52
P S++++++ + P P V K+T K+F K + P N D + G+ +
Sbjct: 16 PSSDDDNQENQPPFPGVLADKITSCIRKSKIFIKPSFSPPPPANTVDMAPPISWRKGQLI 75
Query: 53 GAGTFGVVRQARCISSGE----NXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNHPNIV 108
G G FG V + SGE +Q L +E+ +L+ L+HPNIV
Sbjct: 76 GRGAFGTVYMGMNLDSGELLAVKQVLIAANFASKEKTQAHIQELEEEVKLLKNLSHPNIV 135
Query: 109 RFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRNIVH 168
R+ + I+ + GG + + + G F E +Q+L G++YLH I+H
Sbjct: 136 RYLGTVREDDTLNILLEFVPGGSISSLLEKFGPFPESVVRTYTRQLLLGLEYLHNHAIMH 195
Query: 169 RDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNEL--IHKAAGSMGYVAPEVLTSSGHG 226
RD+K NIL NK + + DFG +K++ + + G+ ++APEV+ +GH
Sbjct: 196 RDIKGANILVDNK---GCIKLADFGASKQVAELATMTGAKSMKGTPYWMAPEVILQTGHS 252
Query: 227 KPCDIWSIGVITYTLLCGYSPFLAE----SADGFIEECTSGQYPVVFHKPYWNNVSKTAK 282
DIWS+G ++ G +P+ + +A FI S H P + +S AK
Sbjct: 253 FSADIWSVGCTVIEMVTGKAPWSQQYKEVAAIFFIGTTKS-------HPPIPDTLSSDAK 305
Query: 283 EFILWALTVSPKRRPTATDLINDIWITS--TEKSTTDL 318
+F+L L P RPTA++L+ ++ E ++TDL
Sbjct: 306 DFLLKCLQEVPNLRPTASELLKHPFVMGKHKESASTDL 343
>Hs20143922 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 27118
Score = 122 bits (305), Expect = 1e-27
Identities = 81/266 (30%), Positives = 132/266 (49%), Gaps = 14/266 (5%)
Query: 46 YIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNHP 105
Y+ + LG G FG+V RC+ + V ++ E+SIL H
Sbjct: 24946 YMIAEDLGRGEFGIVH--RCVETSSKKTYMAKFVKVKGTDQV---LVKKEISILNIARHR 25000
Query: 106 NIVRFKDWFESKEKFYIVTQLATGGELFDRILEKG-KFCEVDAVFIVKQILQGVQYLHQR 164
NI+ + FES E+ ++ + +G ++F+RI + E + V V Q+ + +Q+LH
Sbjct: 25001 NILHLHESFESMEELVMIFEFISGLDIFERINTSAFELNEREIVSYVHQVCEALQFLHSH 25060
Query: 165 NIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELK--DDNELIHKAAGSMGYVAPEVLTS 222
NI H D++PENI+Y + + +I +FG A++LK D+ L+ A Y APEV
Sbjct: 25061 NIGHFDIRPENIIYQTRRSSTIKII-EFGQARQLKPGDNFRLLFTAPE---YYAPEVHQH 25116
Query: 223 SGHGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAK 282
D+WS+G + Y LL G +PFLAE+ IE + +Y F + + +S A
Sbjct: 25117 DVVSTATDMWSLGTLVYVLLSGINPFLAETNQQIIENIMNAEY--TFDEEAFKEISIEAM 25174
Query: 283 EFILWALTVSPKRRPTATDLINDIWI 308
+F+ L K R TA++ + W+
Sbjct: 25175 DFVDRLLVKERKSRMTASEALQHPWL 25200
>Hs20143918 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 27051
Score = 122 bits (305), Expect = 1e-27
Identities = 81/266 (30%), Positives = 132/266 (49%), Gaps = 14/266 (5%)
Query: 46 YIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNHP 105
Y+ + LG G FG+V RC+ + V ++ E+SIL H
Sbjct: 24879 YMIAEDLGRGEFGIVH--RCVETSSKKTYMAKFVKVKGTDQV---LVKKEISILNIARHR 24933
Query: 106 NIVRFKDWFESKEKFYIVTQLATGGELFDRILEKG-KFCEVDAVFIVKQILQGVQYLHQR 164
NI+ + FES E+ ++ + +G ++F+RI + E + V V Q+ + +Q+LH
Sbjct: 24934 NILHLHESFESMEELVMIFEFISGLDIFERINTSAFELNEREIVSYVHQVCEALQFLHSH 24993
Query: 165 NIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELK--DDNELIHKAAGSMGYVAPEVLTS 222
NI H D++PENI+Y + + +I +FG A++LK D+ L+ A Y APEV
Sbjct: 24994 NIGHFDIRPENIIYQTRRSSTIKII-EFGQARQLKPGDNFRLLFTAPE---YYAPEVHQH 25049
Query: 223 SGHGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAK 282
D+WS+G + Y LL G +PFLAE+ IE + +Y F + + +S A
Sbjct: 25050 DVVSTATDMWSLGTLVYVLLSGINPFLAETNQQIIENIMNAEY--TFDEEAFKEISIEAM 25107
Query: 283 EFILWALTVSPKRRPTATDLINDIWI 308
+F+ L K R TA++ + W+
Sbjct: 25108 DFVDRLLVKERKSRMTASEALQHPWL 25133
>Hs20143914 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 26926
Score = 122 bits (305), Expect = 1e-27
Identities = 81/266 (30%), Positives = 132/266 (49%), Gaps = 14/266 (5%)
Query: 46 YIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNHP 105
Y+ + LG G FG+V RC+ + V ++ E+SIL H
Sbjct: 24754 YMIAEDLGRGEFGIVH--RCVETSSKKTYMAKFVKVKGTDQV---LVKKEISILNIARHR 24808
Query: 106 NIVRFKDWFESKEKFYIVTQLATGGELFDRILEKG-KFCEVDAVFIVKQILQGVQYLHQR 164
NI+ + FES E+ ++ + +G ++F+RI + E + V V Q+ + +Q+LH
Sbjct: 24809 NILHLHESFESMEELVMIFEFISGLDIFERINTSAFELNEREIVSYVHQVCEALQFLHSH 24868
Query: 165 NIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELK--DDNELIHKAAGSMGYVAPEVLTS 222
NI H D++PENI+Y + + +I +FG A++LK D+ L+ A Y APEV
Sbjct: 24869 NIGHFDIRPENIIYQTRRSSTIKII-EFGQARQLKPGDNFRLLFTAPE---YYAPEVHQH 24924
Query: 223 SGHGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAK 282
D+WS+G + Y LL G +PFLAE+ IE + +Y F + + +S A
Sbjct: 24925 DVVSTATDMWSLGTLVYVLLSGINPFLAETNQQIIENIMNAEY--TFDEEAFKEISIEAM 24982
Query: 283 EFILWALTVSPKRRPTATDLINDIWI 308
+F+ L K R TA++ + W+
Sbjct: 24983 DFVDRLLVKERKSRMTASEALQHPWL 25008
>Hs19923468 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD and related
proteins
Length = 878
Score = 122 bits (305), Expect = 1e-27
Identities = 81/261 (31%), Positives = 132/261 (50%), Gaps = 10/261 (3%)
Query: 50 KTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNHPNIVR 109
+ LG+G FGVV + +G + + Q L +E++ILQ L HP IV
Sbjct: 555 EVLGSGQFGVVYGGKHRKTGRDVAVKVIDKLRF--PTKQESQLRNEVAILQSLRHPGIVN 612
Query: 110 FKDWFESKEKFYIVTQLATGGELFDRIL--EKGKFCEVDAVFIVKQILQGVQYLHQRNIV 167
+ FE+ EK ++V + G++ + IL EKG+ E F++ QIL +++LH +NIV
Sbjct: 613 LECMFETPEKVFVVME-KLHGDMLEMILSSEKGRLPERLTKFLITQILVALRHLHFKNIV 671
Query: 168 HRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSGHGK 227
H DLKPEN+L + + + DFG A+ + + G+ Y+APEVL + G+ +
Sbjct: 672 HCDLKPENVLLASADPFPQVKLCDFGFAR-IIGEKSFRRSVVGTPAYLAPEVLLNQGYNR 730
Query: 228 PCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKEFILW 287
D+WS+GVI Y L G PF + + + YP W+++S A + I
Sbjct: 731 SLDMWSVGVIMYVSLSGTFPFNEDEDINDQIQNAAFMYPA----SPWSHISAGAIDLINN 786
Query: 288 ALTVSPKRRPTATDLINDIWI 308
L V ++R + ++ W+
Sbjct: 787 LLQVKMRKRYSVDKSLSHPWL 807
>Hs19747267 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 34350
Score = 122 bits (305), Expect = 1e-27
Identities = 81/266 (30%), Positives = 132/266 (49%), Gaps = 14/266 (5%)
Query: 46 YIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNHP 105
Y+ + LG G FG+V RC+ + V ++ E+SIL H
Sbjct: 32178 YMIAEDLGRGEFGIVH--RCVETSSKKTYMAKFVKVKGTDQV---LVKKEISILNIARHR 32232
Query: 106 NIVRFKDWFESKEKFYIVTQLATGGELFDRILEKG-KFCEVDAVFIVKQILQGVQYLHQR 164
NI+ + FES E+ ++ + +G ++F+RI + E + V V Q+ + +Q+LH
Sbjct: 32233 NILHLHESFESMEELVMIFEFISGLDIFERINTSAFELNEREIVSYVHQVCEALQFLHSH 32292
Query: 165 NIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELK--DDNELIHKAAGSMGYVAPEVLTS 222
NI H D++PENI+Y + + +I +FG A++LK D+ L+ A Y APEV
Sbjct: 32293 NIGHFDIRPENIIYQTRRSSTIKII-EFGQARQLKPGDNFRLLFTAPE---YYAPEVHQH 32348
Query: 223 SGHGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAK 282
D+WS+G + Y LL G +PFLAE+ IE + +Y F + + +S A
Sbjct: 32349 DVVSTATDMWSLGTLVYVLLSGINPFLAETNQQIIENIMNAEY--TFDEEAFKEISIEAM 32406
Query: 283 EFILWALTVSPKRRPTATDLINDIWI 308
+F+ L K R TA++ + W+
Sbjct: 32407 DFVDRLLVKERKSRMTASEALQHPWL 32432
>At2g45490 [D] KOG0580 Serine/threonine protein kinase
Length = 288
Score = 122 bits (305), Expect = 1e-27
Identities = 77/265 (29%), Positives = 122/265 (45%), Gaps = 11/265 (4%)
Query: 44 SDYIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLN 103
+D+ G+ LG G FG V AR S + Q L E+ I L
Sbjct: 20 ADFEIGRPLGKGKFGRVYLAREAKSKYIVALKVIFKEQIEKYKIHHQ-LRREMEIQTSLR 78
Query: 104 HPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQ 163
HPNI+R WF E+ +++ + A GGEL+ + + G E A + + Q + Y H
Sbjct: 79 HPNILRLFGWFHDNERIFLILEYAHGGELYGVLKQNGHLTEQQAATYIASLSQALAYCHG 138
Query: 164 RNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSS 223
+ ++HRD+KPEN+L + L I DFG + + + + + G++ Y+APE++ +
Sbjct: 139 KCVIHRDIKPENLLL---DHEGRLKIADFGWSVQSSNKRKTM---CGTLDYLAPEMVENR 192
Query: 224 GHGKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKE 283
H D W++G++ Y L G PF AES + + P NVS+ AK
Sbjct: 193 DHDYAVDNWTLGILCYEFLYGNPPFEAESQKDTFKRILK----IDLSFPLTPNVSEEAKN 248
Query: 284 FILWALTVSPKRRPTATDLINDIWI 308
I L P +R + ++ WI
Sbjct: 249 LISQLLVKDPSKRLSIEKIMQHPWI 273
>7300559 [T] KOG4279 Serine/threonine protein kinase
Length = 1310
Score = 122 bits (305), Expect = 1e-27
Identities = 87/277 (31%), Positives = 129/277 (46%), Gaps = 20/277 (7%)
Query: 52 LGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNHPNIVRFK 111
LG GT+G V AR + S +Q L++E+ + QL H NIVR+
Sbjct: 585 LGKGTYGTVYAAR----DKQTQVRIAIKEVPEKNSQDVQPLHEEIKLHSQLRHRNIVRYL 640
Query: 112 DWFESKEKFYIVTQLATGGELFDRILEKG---KFCEVDAVFIVKQILQGVQYLHQRNIVH 168
F I + GG L D + K K E F KQIL+G++YLH+++IVH
Sbjct: 641 GSCSENGFFKIFMEQVPGGSLSDLLETKWGPLKDNESTMAFYSKQILEGLKYLHEQDIVH 700
Query: 169 RDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSS--GHG 226
RD+K +N+L S + I DFG +K L N + G++ Y+APEV+ G+G
Sbjct: 701 RDIKGDNVLVNTYS--GVVKISDFGTSKRLARINPMTETFTGTLQYMAPEVIDQGVRGYG 758
Query: 227 KPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWN---NVSKTAKE 283
DIWS G + G PF+ + + + V F+K + N +S AK
Sbjct: 759 PAADIWSFGCTNVEMATGKPPFIE------LGSAHAAMFKVGFYKKHPNIPEELSANAKN 812
Query: 284 FILWALTVSPKRRPTATDLINDIWITSTEKSTTDLLP 320
FIL +S RP+A+ L+ D ++ + LP
Sbjct: 813 FILRCFAISVMDRPSASQLLEDPFLQDKPRKVRPALP 849
>SPCC74.03c [T] KOG0583 Serine/threonine protein kinase
Length = 576
Score = 121 bits (304), Expect = 2e-27
Identities = 85/295 (28%), Positives = 142/295 (47%), Gaps = 16/295 (5%)
Query: 17 EPEPVEGHKLTKLFNKVTGQPSSYVNK---SDYIFGKTLGAGTFGVVRQARCISSGENXX 73
+P+ V+ + + + N P ++K YI +TLG G+FG V+ A + +
Sbjct: 2 QPQEVDLMENSTMRNGARVLPPEAISKRHIGPYIIRETLGEGSFGKVKLATHYKTQQKVA 61
Query: 74 XXXXXXXXXXGQSVQLQMLYDELSILQQLNHPNIVRFKDWFESKEKFYIVTQLATGGELF 133
+ +++ E+S L+ L HP+I++ D + +V + A GGELF
Sbjct: 62 LKFISRQLLKKSDMHMRV-EREISYLKLLRHPHIIKLYDVITTPTDIVMVIEYA-GGELF 119
Query: 134 DRILEKGKFCEVDAVFIVKQILQGVQYLHQRNIVHRDLKPENILYLNKSDDSPLVIGDFG 193
D I+EK + E + +QI+ ++Y H+ IVHRDLKPEN+L D+ + I DFG
Sbjct: 120 DYIVEKKRMTEDEGRRFFQQIICAIEYCHRHKIVHRDLKPENLLL---DDNLNVKIADFG 176
Query: 194 IAKELKDDNELIHKAAGSMGYVAPEVLTSSGHGKP-CDIWSIGVITYTLLCGYSPFLAES 252
++ + D N + + GS Y APEV+ + P D+WS G++ Y +L G PF E
Sbjct: 177 LSNIMTDGN-FLKTSCGSPNYAAPEVINGKLYAGPEVDVWSCGIVLYVMLVGRLPFDDEF 235
Query: 253 ADGFIEECTSGQYPVVFHKPYWNNVSKTAKEFILWALTVSPKRRPTATDLINDIW 307
++ S Y + + +S A+ I + P +R T ++ D W
Sbjct: 236 IPNLFKKVNSCVYVMP------DFLSPGAQSLIRRMIVADPMQRITIQEIRRDPW 284
>HsM8923212 [T] KOG4717 Serine/threonine protein kinase
Length = 244
Score = 121 bits (304), Expect = 2e-27
Identities = 76/240 (31%), Positives = 122/240 (50%), Gaps = 13/240 (5%)
Query: 46 YIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNHP 105
Y KTLG G F VV+ AR + +GE ++ L+ E+ ++ + HP
Sbjct: 16 YDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKL--DTLATGHLFQEVRCMKLVQHP 73
Query: 106 NIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVD-AVFIVKQILQGVQYLHQR 164
NIVR + +++ K Y++ +L GG++FD I++ + D A QI+ + Y H+
Sbjct: 74 NIVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAISYCHKL 133
Query: 165 NIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSG 224
++VHRDLKPEN+++ K + + DFG + + + +L + GS+ Y APE+L
Sbjct: 134 HVVHRDLKPENVVFFEK--QGLVKLTDFGFSNKFQPGKKLT-TSCGSLAYSAPEILLGDE 190
Query: 225 HGKPC-DIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKE 283
+ P DIWS+GVI + L+C PF + + +Y V H VSK KE
Sbjct: 191 YDAPAVDIWSLGVILFMLVCEQPPFQEANDSETLTMIMDCKYTVPSH------VSKECKE 244
>CE28251 [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 469
Score = 121 bits (304), Expect = 2e-27
Identities = 73/242 (30%), Positives = 126/242 (51%), Gaps = 17/242 (7%)
Query: 92 LYDELSILQQLNHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVD----- 146
+ +E+ ++++L+HPNIV D + Y+V + GGE F ++++ K+ ++
Sbjct: 218 IQNEVEVMKKLSHPNIVAIYDCITVAKYSYMVIEYVGGGEFFSKLVDS-KYNQMGLGESL 276
Query: 147 AVFIVKQILQGVQYLHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIH 206
+ Q++ V YLH I HRD+KPENIL NK++ L + DFG+A K+ +
Sbjct: 277 GKYFAFQLIDAVLYLHSVGICHRDIKPENILCSNKAERCILKLTDFGMA---KNSVNRMK 333
Query: 207 KAAGSMGYVAPEVLTSSG--HGKPCDIWSIGVITYTLLCGYSPFLAESAD-GFIEECTSG 263
G+ Y APE++ + G + DIWS+G + + GY PF E D E+ +G
Sbjct: 334 THCGTPSYCAPEIVANQGVEYTPKVDIWSLGCVLFITFSGYPPFSEEYTDLKMDEQVLTG 393
Query: 264 QYPVVFHKPYWNNVSKTAKEFILWALTVSPKRRPTATDLINDIWITSTE--KSTTDLLPE 321
+ +F W+ ++ + I W LTV P RP+A +L++ W+ + + D+L
Sbjct: 394 R---LFFHEQWHRITDETQNMIQWMLTVEPLIRPSAVELMSTQWMKCADCLSAKQDILKS 450
Query: 322 IR 323
I+
Sbjct: 451 IQ 452
>At5g07070 [T] KOG0583 Serine/threonine protein kinase
Length = 456
Score = 121 bits (304), Expect = 2e-27
Identities = 71/206 (34%), Positives = 106/206 (50%), Gaps = 8/206 (3%)
Query: 46 YIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNHP 105
Y G+ LG GTF V R + E+ + Q + E+S+++ HP
Sbjct: 12 YEVGRLLGQGTFAKVYFGRSNHTNESVAIKMIDKDKVMRVGLS-QQIKREISVMRIAKHP 70
Query: 106 NIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRN 165
N+V + +K + Y V + GGELF+++ KGK E A Q++ V + H R
Sbjct: 71 NVVELYEVMATKSRIYFVIEYCKGGELFNKV-AKGKLKEDVAWKYFYQLISAVDFCHSRG 129
Query: 166 IVHRDLKPENILYLNKSDDSPLVIGDFGIA--KELKDDNELIHKAAGSMGYVAPEVLTSS 223
+ HRD+KPEN+L D+ L + DFG++ + K + L+H G+ YVAPEV+
Sbjct: 130 VYHRDIKPENLLL---DDNDNLKVSDFGLSALADCKRQDGLLHTTCGTPAYVAPEVINRK 186
Query: 224 GH-GKPCDIWSIGVITYTLLCGYSPF 248
G+ G DIWS GV+ + LL GY PF
Sbjct: 187 GYEGTKADIWSCGVVLFVLLAGYLPF 212
>At2g34180 [T] KOG0583 Serine/threonine protein kinase
Length = 502
Score = 121 bits (304), Expect = 2e-27
Identities = 93/295 (31%), Positives = 138/295 (46%), Gaps = 25/295 (8%)
Query: 26 LTKLFNKVTGQPSS---------YVNKSDYIFGKTLGAGTFGVVRQARCISSGENXXXXX 76
+TK NK T P S + Y GK LG G+F V AR I SGE+
Sbjct: 28 VTKNTNKETSTPESPRSPRTPQGSILMDKYEIGKLLGHGSFAKVYLARNIHSGEDVAIKV 87
Query: 77 XXXXXXXGQSVQLQMLYDELSILQQLNHPNIVRFKDWFESKEKFYIVTQLATGGELFDRI 136
+S + E+SIL+++ HP IV + +K K YIV + GGEL++ +
Sbjct: 88 IDKEKIV-KSGLAGHIKREISILRRVRHPYIVHLLEVMATKTKIYIVMEYVRGGELYNTV 146
Query: 137 LEKGKFCEVDAVFIVKQILQGVQYLHQRNIVHRDLKPENILYLNKSDDSPLVIGDFG--- 193
+G+ E A +Q++ V + H R + HRDLK EN+L D + + DFG
Sbjct: 147 -ARGRLREGTARRYFQQLISSVAFCHSRGVYHRDLKLENLLL---DDKGNVKVSDFGLSV 202
Query: 194 IAKELKDDNELIHKAAGSMGYVAPEVLTSSGH-GKPCDIWSIGVITYTLLCGYSPFLAES 252
++++LK + + G+ Y+APEVLT G+ G DIWS GVI + L+ GY PF ++
Sbjct: 203 VSEQLKQEG-ICQTFCGTPAYLAPEVLTRKGYEGAKADIWSCGVILFVLMAGYLPFDDKN 261
Query: 253 ADGFIEECTSGQYPVVFHKPYWNNVSKTAKEFILWALTVSPKRRPTATDLINDIW 307
+ GQ F P W S + L +P R T +++ W
Sbjct: 262 ILVMYTKIYKGQ----FKCPKW--FSPELARLVTRMLDTNPDTRITIPEIMKHRW 310
>At2g23030 [T] KOG0583 Serine/threonine protein kinase
Length = 339
Score = 121 bits (304), Expect = 2e-27
Identities = 85/267 (31%), Positives = 126/267 (46%), Gaps = 16/267 (5%)
Query: 46 YIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNHP 105
Y K LG G FG+ R R + E ++V +++ + LNHP
Sbjct: 4 YEMVKDLGFGNFGLARLMRNKQTNELVAVKFIDRGYKIDENVAREIINH-----RALNHP 58
Query: 106 NIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRN 165
NIVRFK+ + IV + A GGELF+RI G+F E +A + +Q++ GV YLH
Sbjct: 59 NIVRFKEVVLTPTHLGIVMEYAAGGELFERISSVGRFSEAEARYFFQQLICGVHYLHALQ 118
Query: 166 IVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIH----KAAGSMGYVAPEVLT 221
I HRDLK EN L L+ S L I DFG +K + ++H G+ Y+APEV
Sbjct: 119 ICHRDLKLENTL-LDGSPAPRLKICDFGYSK-----SSVLHSNPKSTVGTPAYIAPEVFC 172
Query: 222 SSGH-GKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKT 280
S + GK D+WS GV Y +L G PF + V + P + ++S+
Sbjct: 173 RSEYDGKSVDVWSCGVALYVMLVGAYPFEDPKDPRNFRKTVQKIMAVNYKIPGYVHISED 232
Query: 281 AKEFILWALTVSPKRRPTATDLINDIW 307
++ + +P R T ++ + W
Sbjct: 233 CRKLLSRIFVANPLHRSTLKEIKSHAW 259
>SPAC57A10.02 [D] KOG0588 Serine/threonine protein kinase
Length = 775
Score = 121 bits (303), Expect = 2e-27
Identities = 73/214 (34%), Positives = 117/214 (54%), Gaps = 11/214 (5%)
Query: 86 SVQLQMLYDELSILQQLNHPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEV 145
S Q + EL +L+ + HPN+++ D ++E+ ++V + GGELFD +L KG F E
Sbjct: 49 SSQQARIEGELVLLRLIEHPNVLQLIDVISAQEQLFVVVEYMPGGELFDCMLRKGSFTEQ 108
Query: 146 DAVFIVKQILQGVQYLHQRNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELI 205
D + QIL G++Y H+ +I HRDLKPEN LYL+ + IG+FG+A ++ +L+
Sbjct: 109 DTAKFLWQILCGLEYCHKLHICHRDLKPEN-LYLDA--HGSIKIGEFGMA-SIQQPGKLL 164
Query: 206 HKAAGSMGYVAPEVLTSSGH-GKPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQ 264
+ GS Y +PE++ + G DIWS G+I + LL G PF ++ + + GQ
Sbjct: 165 QTSCGSPHYASPEIIMGRSYDGCASDIWSCGIIFFALLTGKLPFDDDNIRSLLLKVCQGQ 224
Query: 265 YPVVFHKPYWNNVSKTAKEFILWALTVSPKRRPT 298
+ + +N+S A+ + L V R T
Sbjct: 225 FEMP------SNISPQAQHLLYRMLDVDSSTRIT 252
>Hs7657214 [T] KOG0583 Serine/threonine protein kinase
Length = 714
Score = 120 bits (302), Expect = 3e-27
Identities = 78/269 (28%), Positives = 128/269 (46%), Gaps = 13/269 (4%)
Query: 45 DYIFG-KTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLN 103
+Y+ G + LG G+F VR+ + +GE + + L E I Q +
Sbjct: 60 NYLIGSRKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQQMIR 119
Query: 104 HPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQ 163
HPNI + D E++ +Y+V +L GG L +I EK + E +A ++Q++ V++LH+
Sbjct: 120 HPNITQLLDILETENSYYLVMELCPGGNLMHKIYEKKRLEESEARRYIRQLISAVEHLHR 179
Query: 164 RNIVHRDLKPENILYLNKSDDSPLVIGDFGIAK--ELKDDNELIHKAAGSMGYVAPEVLT 221
+VHRDLK EN+L +D+ + + DFG++ + ++ GS Y APE+L
Sbjct: 180 AGVVHRDLKIENLLL---DEDNNIKLIDFGLSNCAGILGYSDPFSTQCGSPAYAAPELLA 236
Query: 222 SSGHGKPCDIWSIGVITYTLLCGYSPFLAE--SADGFIEECTSGQYPVVFHKPYWNNVSK 279
+G D+WSIGV Y +L G PF E S ++ + P +S
Sbjct: 237 RKKYGPKIDVWSIGVNMYAMLTGTLPFTVEPFSLRALYQKMVDKEM-----NPLPTQLST 291
Query: 280 TAKEFILWALTVSPKRRPTATDLINDIWI 308
A F+ L P +RP + + W+
Sbjct: 292 GAISFLRSLLEPDPVKRPNIQQALANRWL 320
>Hs4506739 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 495
Score = 120 bits (302), Expect = 3e-27
Identities = 74/250 (29%), Positives = 124/250 (49%), Gaps = 12/250 (4%)
Query: 50 KTLGAGTFGVVRQARCISS---GENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLNHPN 106
+ LG G +G V Q R + G+ + E +IL+ + HP
Sbjct: 84 RVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNILESVKHPF 143
Query: 107 IVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQRNI 166
IV F++ K Y++ + +GGELF + +G F E A F + +I + +LH + I
Sbjct: 144 IVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITLALGHLHSQGI 203
Query: 167 VHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSSGHG 226
++RDLKPENI+ S + + DFG+ KE + + H G++ Y+APE+L SGH
Sbjct: 204 IYRDLKPENIML---SSQGHIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEILVRSGHN 260
Query: 227 KPCDIWSIGVITYTLLCGYSPFLAESADGFIEECTSGQYPVVFHKPYWNNVSKTAKEFIL 286
+ D WS+G + Y +L G PF AE+ +++ G+ + PY ++ A++ +
Sbjct: 261 RAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLAL---PPY---LTPDARDLVK 314
Query: 287 WALTVSPKRR 296
L +P +R
Sbjct: 315 KFLKRNPSQR 324
>Hs18596354 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 304
Score = 120 bits (302), Expect = 3e-27
Identities = 69/189 (36%), Positives = 102/189 (53%), Gaps = 10/189 (5%)
Query: 44 SDYIFGKTLGAGTFGVVRQARCISSGENXXXXXXXXXXXXGQSVQLQMLYDELSILQQLN 103
S Y + LG+G F V A+ S G+ ++ +E+++L++++
Sbjct: 96 SVYEIRERLGSGAFSEVVLAQERGSAHLVALKCIPKKALRGKEALVE---NEIAVLRRIS 152
Query: 104 HPNIVRFKDWFESKEKFYIVTQLATGGELFDRILEKGKFCEVDAVFIVKQILQGVQYLHQ 163
HPNIV +D ES Y+ +L TGGELFDRI+E+G + E DA +V Q+L V YLH
Sbjct: 153 HPNIVALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGAVSYLHS 212
Query: 164 RNIVHRDLKPENILYLNKSDDSPLVIGDFGIAKELKDDNELIHKAAGSMGYVAPEVLTSS 223
IVHRDLKPEN+LY +DS +++ DFG++K ++ A G+ GYV
Sbjct: 213 LGIVHRDLKPENLLYATPFEDSKIMVSDFGLSK--IQAGNMLGTACGTPGYVG-----EG 265
Query: 224 GHGKPCDIW 232
H + C W
Sbjct: 266 RHPEACWEW 274
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.315 0.134 0.388
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,905,311
Number of Sequences: 60738
Number of extensions: 1060515
Number of successful extensions: 8126
Number of sequences better than 1.0e-05: 1678
Number of HSP's better than 0.0 without gapping: 417
Number of HSP's successfully gapped in prelim test: 1262
Number of HSP's that attempted gapping in prelim test: 4463
Number of HSP's gapped (non-prelim): 1930
length of query: 427
length of database: 30,389,216
effective HSP length: 109
effective length of query: 318
effective length of database: 23,768,774
effective search space: 7558470132
effective search space used: 7558470132
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)