ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI6287 good E KOG1286 Amino acid transport and metabolism Amino acid transporters
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI6287 2189107 2187389 -573
(573 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YOR348c [E] KOG1286 Amino acid transporters 741 0.0
SPAC869.10c [E] KOG1286 Amino acid transporters 542 e-154
YPL265w [E] KOG1286 Amino acid transporters 351 1e-96
YNL268w [E] KOG1286 Amino acid transporters 332 1e-90
YNL270c [E] KOG1286 Amino acid transporters 320 5e-87
YEL063c [E] KOG1286 Amino acid transporters 319 8e-87
SPCC777.04 [E] KOG1286 Amino acid transporters 314 3e-85
YKR039w [E] KOG1286 Amino acid transporters 303 4e-82
YBR132c [E] KOG1286 Amino acid transporters 283 6e-76
YGR191w [E] KOG1286 Amino acid transporters 282 1e-75
SPBC19F8.06c [E] KOG1286 Amino acid transporters 259 8e-69
SPCC965.11c [E] KOG1286 Amino acid transporters 255 1e-67
SPAP7G5.06 [E] KOG1286 Amino acid transporters 255 1e-67
SPBPB2B2.01 [E] KOG1286 Amino acid transporters 255 1e-67
YCL025c [E] KOG1286 Amino acid transporters 251 3e-66
YPL274w [E] KOG1286 Amino acid transporters 247 3e-65
YDR508c [E] KOG1286 Amino acid transporters 247 4e-65
SPBC1652.02 [E] KOG1286 Amino acid transporters 244 2e-64
YOL020w [E] KOG1286 Amino acid transporters 243 6e-64
YLL061w [E] KOG1286 Amino acid transporters 242 1e-63
SPBC359.03c [E] KOG1286 Amino acid transporters 238 2e-62
SPCPB1C11.02 [E] KOG1286 Amino acid transporters 236 7e-62
YBR069c [E] KOG1286 Amino acid transporters 230 5e-60
YBR068c [E] KOG1286 Amino acid transporters 229 9e-60
YDR046c [E] KOG1286 Amino acid transporters 227 4e-59
YFL055w [E] KOG1286 Amino acid transporters 216 7e-56
SPAC1039.09 [E] KOG1286 Amino acid transporters 216 7e-56
YDR160w [E] KOG1286 Amino acid transporters 188 2e-47
SPAC869.11 [E] KOG1286 Amino acid transporters 167 5e-41
SPBC359.01 [E] KOG1286 Amino acid transporters 88 3e-17
Hs6912670 [E] KOG1287 Amino acid transporters 55 4e-07
7293641 [E] KOG1286 Amino acid transporters 52 3e-06
Hs14777542 [E] KOG1286 Amino acid transporters 50 7e-06
>YOR348c [E] KOG1286 Amino acid transporters
Length = 627
Score = 741 bits (1913), Expect = 0.0
Identities = 358/541 (66%), Positives = 423/541 (78%), Gaps = 6/541 (1%)
Query: 34 DSEKNGSLPNKPQSGDHNLKKGLKSAHIQLIAIGGCIGTGLFVGTSSTLYKCGPAGLFIS 93
D EK+ S+ S H LK+GL+S H+QLIA+GG IGTGL VGTSSTL+ CGPAGLFIS
Sbjct: 90 DLEKSPSVDG--DSEPHKLKQGLQSRHVQLIALGGAIGTGLLVGTSSTLHTCGPAGLFIS 147
Query: 94 YCIMSTIIYPVMNALAEMVCFLPGLPDENETGGSISTLCTRYVDSSLGFAVGWNYVYCYV 153
Y I+S +IYP+M AL EMVCFLPG D +++ GS + L TRYVD SLGFA GWNY YCYV
Sbjct: 148 YIIISAVIYPIMCALGEMVCFLPG--DGSDSAGSTANLVTRYVDPSLGFATGWNYFYCYV 205
Query: 154 ILVAAECTAASGVVTYWTTAVPKAAWITIFLGIIVVLNCTAVEFYGTSEAIFCSLKIFCI 213
ILVAAECTAASGVV YWTTAVPK WITIFL ++V+LN +AV+ YG SE F S+KI CI
Sbjct: 206 ILVAAECTAASGVVEYWTTAVPKGVWITIFLCVVVILNFSAVKVYGESEFWFASIKILCI 265
Query: 214 LGIIIVSIVLFFGGGPNHDRLGFRFWKDPGAWAYHLADGGAGRLSDIITGVIRAGFAFIL 273
+G+II+S +LF+GGGPNHDRLGFR+W+ PGA+A+HL G G +DI TG+I+ FAFIL
Sbjct: 266 VGLIILSFILFWGGGPNHDRLGFRYWQHPGAFAHHLTGGSLGNFTDIYTGIIKGAFAFIL 325
Query: 274 GPELVVLTSTEAQDSRRNIEKAARRFVWRLIFFYCVSSLCAGVIVSRNDPVLLNALSQGK 333
GPELV +TS E D RRNI KA+RRFVWRLIFFY + +L VIV NDP L+NAL+QGK
Sbjct: 326 GPELVCMTSAECADQRRNIAKASRRFVWRLIFFYVLGTLAISVIVPYNDPTLVNALAQGK 385
Query: 334 PGAGSSPFVIGIQNAGIKVLPHIINVCILSSAWSSGNSFMYATTRSLLSLSQEGYAPKIF 393
PGAGSSPFVIGIQNAGIKVLPHIIN CIL+SAWS+ N+FM+A+TRSLL+++Q G APK
Sbjct: 386 PGAGSSPFVIGIQNAGIKVLPHIINGCILTSAWSAANAFMFASTRSLLTMAQTGQAPKCL 445
Query: 394 NRVNRWGVPYTGVAFATAFSCLAYLNVSSSTADVFNWFSNISTISGFLGWICSGVAYLRF 453
R+N+WGVPY V + SCLAYLNVSSSTADVFNWFSNISTISGFLGW+C +AYLRF
Sbjct: 446 GRINKWGVPYVAVGVSFLCSCLAYLNVSSSTADVFNWFSNISTISGFLGWMCGCIAYLRF 505
Query: 454 RKAVFFNNLYDRLPFKTPFQPYFTWFYXXXXXXXXXXNGYESFV--HWNYKDFIAAYITL 511
RKA+F+N LYDRLPFKT QPY WF NGY F+ +W DFIAAYITL
Sbjct: 506 RKAIFYNGLYDRLPFKTWGQPYTVWFSLIVIGIITITNGYAIFIPKYWRVADFIAAYITL 565
Query: 512 PLFLILWLGHKAYTRTWSQWMISVSEIDVTTGLREIEEETKELNARRIPPRNLWEKILEW 571
P+FL+LW GHK YTRTW QW + VSEIDVTTGL EIEE+++E+ R+PP +K L+
Sbjct: 566 PIFLVLWFGHKLYTRTWRQWWLPVSEIDVTTGLVEIEEKSREIEEMRLPPTGFKDKFLDA 625
Query: 572 L 572
L
Sbjct: 626 L 626
>SPAC869.10c [E] KOG1286 Amino acid transporters
Length = 552
Score = 542 bits (1397), Expect = e-154
Identities = 284/522 (54%), Positives = 357/522 (67%), Gaps = 11/522 (2%)
Query: 53 KKGLKSAHIQLIAIGGCIGTGLFVGTSSTLYKCGPAGLFISYCIMSTIIYPVMNALAEMV 112
K+ LKS H+QLIAIGGCIGTGLFVG+ S L + GPA LF+SY IMS +I+ VMNAL EM
Sbjct: 39 KRALKSRHVQLIAIGGCIGTGLFVGSGSALSESGPASLFLSYVIMSFVIWTVMNALGEMC 98
Query: 113 CFLPGLPDENETGGSISTLCTRYVDSSLGFAVGWNYVYCYVILVAAECTAASGVVTYWTT 172
+LP +G S T RYVD+SL FA GWNY Y YV LVA+E TAAS V+ YWT
Sbjct: 99 TYLP------LSGASPITYIERYVDASLAFAAGWNYWYAYVFLVASEVTAASIVIEYWTY 152
Query: 173 AVPKAAWITIFLGIIVVLNCTAVEFYGTSEAIFCSLKIFCILGIIIVSIVLFFGGGPNHD 232
AVP A WI I L ++ VLN V+++G +E F +K+ I+G+II+ +V+FFGG P HD
Sbjct: 153 AVPTAGWIAILLFLVAVLNSFFVKWFGETEFWFAIIKVIAIVGLIILGVVIFFGGTPKHD 212
Query: 233 RLGFRFWKDPGAWAYHLADGGAGRLSDIITGVIRAGFAFILGPELVVLTSTEAQDSRRNI 292
RLGFR+WK A+ ++ G +GR + VI++GFAFIL PELV+ ++ E + RRNI
Sbjct: 213 RLGFRYWKHGLAFREYIVKGASGRFVGFWSAVIKSGFAFILAPELVIFSAGETEAPRRNI 272
Query: 293 EKAARRFVWRLIFFYCVSSLCAGVIVSRNDPVLLNALSQGKPGAGSSPFVIGIQNAGIKV 352
KA RF++RLIFFY SL GVI S DP LLNA+S G GA +SPFVIGIQNA I V
Sbjct: 273 PKATSRFIYRLIFFYIFGSLTIGVITSSKDPRLLNAISSGASGAAASPFVIGIQNAEIPV 332
Query: 353 LPHIINVCILSSAWSSGNSFMYATTRSLLSLSQEGYAPKIFNRVNRWGVPYTGVAFATAF 412
L HIIN IL+SA SSGNSF++A +RS+ SL++E APKIF NRWGVP VA F
Sbjct: 333 LNHIINAVILTSACSSGNSFLFAGSRSIYSLAKEHQAPKIFKYCNRWGVPVISVAVTVLF 392
Query: 413 SCLAYLNVSSSTADVFNWFSNISTISGFLGWICSGVAYLRFRKAVFFNNLYDRLPFKTPF 472
+CLA+LN S+S A VFNWF N+STISGFL WIC VAYL+FRKA+ NNL++ P+KTPF
Sbjct: 393 ACLAFLNASASAAVVFNWFCNLSTISGFLAWICVLVAYLQFRKAMILNNLWETRPYKTPF 452
Query: 473 QPYFTWFYXXXXXXXXXXNGYESFVHWNYK--DFIAAYITLPLFLILWLGHKAYTRTWSQ 530
QPY T+ NG+ FV + +FIAAYITLP+FL+L++ HK ++R WS
Sbjct: 453 QPYATYLTLFLLALITLTNGFTVFVGHTFTAGNFIAAYITLPIFLVLYVAHKLWSRNWS- 511
Query: 531 WMISVSEIDVTTGLREIEEETKELNARRIPPRNLWEKILEWL 572
+ + EIDVTTG+ E E + A PRN+ EKI W+
Sbjct: 512 FGKRIEEIDVTTGVAEAEALEQMYPAP--VPRNIIEKIWFWI 551
>YPL265w [E] KOG1286 Amino acid transporters
Length = 608
Score = 351 bits (901), Expect = 1e-96
Identities = 198/550 (36%), Positives = 314/550 (57%), Gaps = 33/550 (6%)
Query: 22 QVYELDLTSYSNDSEKNGSLPNK--------PQSGDHN--LKKGLKSAHIQLIAIGGCIG 71
++Y +DL + S + S P D N L+K LK+ HI +IAIGG +G
Sbjct: 42 EIYNIDLEENNVSSRSSTSTSPSARDDSFAVPDGKDENTRLRKDLKARHISMIAIGGSLG 101
Query: 72 TGLFVGTSSTLYKCGPAGLFISYCIMSTIIYPVMNALAEMVCFLPGLPDENETGGSISTL 131
TGL +GT + L GP + I+Y + +++ M L EM ++P ++
Sbjct: 102 TGLLIGTGTALLTGGPVAMLIAYAFVGLLVFYTMACLGEMASYIPL--------DGFTSY 153
Query: 132 CTRYVDSSLGFAVGWNYVYCYVILVAAECTAASGVVTYWTTA--VPKAAWITIFLGIIVV 189
+RYVD +LGFA+G+ Y++ Y IL + TAA+ V+ YW + V WITIFL +IV
Sbjct: 154 ASRYVDPALGFAIGYTYLFKYFILPPNQLTAAALVIQYWISRDRVNPGVWITIFLVVIVA 213
Query: 190 LNCTAVEFYGTSEAIFCSLKIFCILGIIIVSIVLFFGGGPNHDRLGFRFWKDPGAWAYHL 249
+N V+F+G E S K+ +LG+I++ ++ GGGPNHDRLGFR+W+DPGA+ +
Sbjct: 214 INVVGVKFFGEFEFWLSSFKVMVMLGLILLLFIIMLGGGPNHDRLGFRYWRDPGAFKEYS 273
Query: 250 A--DGGAGRLSDIITGVIRAGFAFILGPELVVLTSTEAQDSRRNIEKAARRFVWRLIFFY 307
GG G+ + + + F++ G EL + +EA++ R+++ KA + V+R+I FY
Sbjct: 274 TAITGGKGKFVSFVAVFVYSLFSYT-GIELTGIVCSEAENPRKSVPKAIKLTVYRIIVFY 332
Query: 308 CVSSLCAGVIVSRNDPVLLNALSQGKP-GAGSSPFVIGIQNAGIKVLPHIINVCILSSAW 366
+ G+ V+ NDP LL+ ++GK A +SPFV+ IQN+GI+VLPHI N C+L +
Sbjct: 333 LCTVFLLGMCVAYNDPRLLS--TKGKSMSAAASPFVVAIQNSGIEVLPHIFNACVLVFVF 390
Query: 367 SSGNSFMYATTRSLLSLSQEGYAPKIFNRVNRWGVPYTGVAFATAFSCLAYLNVSSSTAD 426
S+ NS +Y ++R+L +L+ +G APKIF + +RWGVPY + + F LAY+NVSS +A
Sbjct: 391 SACNSDLYVSSRNLYALAIDGKAPKIFAKTSRWGVPYNALILSVLFCGLAYMNVSSGSAK 450
Query: 427 VFNWFSNISTISGFLGWICSGVAYLRFRKAVFFNNL-YDRLPFKTPFQPYFTWFYXXXXX 485
+FN+F N+ ++ G L WI + Y+ F KA + + + P Q Y +F
Sbjct: 451 IFNYFVNVVSMFGILSWITILIVYIYFDKACRAQGIDKSKFAYVAPGQRYGAYFALFFCI 510
Query: 486 XXXXXNGYESFV--HWNYKDFIAAYITLPLFLILWLGHKAYTRTWSQWMISVSEIDVTTG 543
+ F+ ++YK FI YI LP+++I W G+K +T +I +++D+ T
Sbjct: 511 LIALIKNFTVFLGHKFDYKTFITGYIGLPVYIISWAGYKLIYKT---KVIKSTDVDLYT- 566
Query: 544 LREIEEETKE 553
+EI + +E
Sbjct: 567 FKEIYDREEE 576
>YNL268w [E] KOG1286 Amino acid transporters
Length = 611
Score = 332 bits (850), Expect = 1e-90
Identities = 195/560 (34%), Positives = 300/560 (52%), Gaps = 25/560 (4%)
Query: 11 GETSVVDKQTGQVYELDLTSYSNDSEKNGSLPNKPQSGDHNLKKGLKSAHIQLIAIGGCI 70
G + V+ T + L + S+ D ++ + D ++K+ LK HI +IA+GG I
Sbjct: 68 GAIADVNSITNSLTRLQVVSHETDINED---EEEAHYEDKHVKRALKQRHIGMIALGGTI 124
Query: 71 GTGLFVGTSSTLYKCGPAGLFISYCIMSTIIYPVMNALAEMVCFLPGLPDENETGGSIST 130
GTGLFVG S+ L GP G I+Y M TI+Y V +L EM F+P SI+
Sbjct: 125 GTGLFVGISTPLSNAGPVGSLIAYIFMGTIVYFVTQSLGEMATFIP-------VTSSITV 177
Query: 131 LCTRYVDSSLGFAVGWNYVYCYVILVAAECTAASGVVTYWTTAVPKAAWITIFLGIIVVL 190
R++ + G + G+ Y + + I A E + V+ YWT VP AAWI IF II ++
Sbjct: 178 FSKRFLSPAFGVSNGYMYWFNWAITYAVEVSVIGQVIEYWTDKVPLAAWIAIFWVIITLM 237
Query: 191 NCTAVEFYGTSEAIFCSLKIFCILGIIIVSIVLFFGGGPNHDRLGFRFWKDPGAWAYHL- 249
N V+ YG E S+K+ I+G +I ++++ GG + +GFR+W++PGAW +
Sbjct: 238 NFFPVKVYGEFEFWVASVKVLAIMGYLIYALIIVCGGS-HQGPIGFRYWRNPGAWGPGII 296
Query: 250 -ADGGAGRLSDIITGVIRAGFAFILGPELVVLTSTEAQDSRRNIEKAARRFVWRLIFFYC 308
+D GR ++ +I A F + G ELV +T+ EA + R+ + +A + V+R++ FY
Sbjct: 297 SSDKSEGRFLGWVSSLINAAFTY-QGTELVGITAGEAANPRKTVPRAINKVVFRIVLFYI 355
Query: 309 VSSLCAGVIVSRNDPVLLNALSQGKPGAGSSPFVIGIQNAGIKVLPHIINVCILSSAWSS 368
+S G++V ND + LS SSPFVI IQNAG LP I N +L + S+
Sbjct: 356 MSLFFIGLLVPYND----SRLSASSAVIASSPFVISIQNAGTYALPDIFNAVVLITVVSA 411
Query: 369 GNSFMYATTRSLLSLSQEGYAPKIFNRVNRWGVPYTGVAFATAFSCLAYLNVSSSTADVF 428
NS +Y +R L SL++ G APK F V R GVPY GV A LA+L V+++ F
Sbjct: 412 ANSNVYVGSRVLYSLARTGNAPKQFGYVTRQGVPYLGVVCTAALGLLAFLVVNNNANTAF 471
Query: 429 NWFSNISTISGFLGWICSGVAYLRFRKAVFFNNL-YDRLPFKTPFQPYFTWFYXXXXXXX 487
NW NIST++G W+ +A++RF +A+ + D LPFK PY ++
Sbjct: 472 NWLINISTLAGLCAWLFISLAHIRFMQALKHRGISRDDLPFKAKLMPYGAYYAAFFVTVI 531
Query: 488 XXXNGYESFVHWNYKDFIAAYITLPLFLILWLGHKAYTRTWSQWMISVSEIDVTTGLREI 547
G+++F + +F +YI+L L ++++G + Y + W + +ID+ + REI
Sbjct: 532 IFIQGFQAFCPFKVSEFFTSYISLILLAVVFIGCQIYYKCRFIW--KLEDIDIDSDRREI 589
Query: 548 EEETKELNARRIPPRNLWEK 567
E E + P+NLWEK
Sbjct: 590 EAIIWEDD----EPKNLWEK 605
>YNL270c [E] KOG1286 Amino acid transporters
Length = 573
Score = 320 bits (819), Expect = 5e-87
Identities = 179/502 (35%), Positives = 271/502 (53%), Gaps = 18/502 (3%)
Query: 52 LKKGLKSAHIQLIAIGGCIGTGLFVGTSSTLYKCGPAGLFISYCIMSTIIYPVMNALAEM 111
+K+ LK HI +IA+GG IGTGL +G L GP G ISY M T+IY V +L EM
Sbjct: 66 VKRKLKQRHIGMIALGGTIGTGLIIGIGPPLAHAGPVGALISYLFMGTVIYSVTQSLGEM 125
Query: 112 VCFLPGLPDENETGGSISTLCTRYVDSSLGFAVGWNYVYCYVILVAAECTAASGVVTYWT 171
V F+P S S R++ +LG G+ Y + A E + V+ YWT
Sbjct: 126 VTFIP-------VTSSFSVFAQRFLSPALGATNGYMYWLSWCFTFALELSVLGKVIQYWT 178
Query: 172 TAVPKAAWITIFLGIIVVLNCTAVEFYGTSEAIFCSLKIFCILGIIIVSIVLFFGGGPNH 231
AVP AAWI IF ++ +N V++YG E S+K+ +LG II S + G G +
Sbjct: 179 EAVPLAAWIVIFWCLLTSMNMFPVKYYGEFEFCIASIKVIALLGFIIFSFCVVCGAGQSD 238
Query: 232 DRLGFRFWKDPGAWAYHL--ADGGAGRLSDIITGVIRAGFAFILGPELVVLTSTEAQDSR 289
+GFR+W++PGAW + +D GR ++ +I A F + G ELV +T+ EA + R
Sbjct: 239 GPIGFRYWRNPGAWGPGIISSDKNEGRFLGWVSSLINAAFTY-QGTELVGITAGEAANPR 297
Query: 290 RNIEKAARRFVWRLIFFYCVSSLCAGVIVSRNDPVLLNALSQGKPGAGSSPFVIGIQNAG 349
+ + +A ++ V R++ FY +S G++V NDP L SSPF+I I+N+G
Sbjct: 298 KALPRAIKKVVVRILVFYILSLFFIGLLVPYNDP----KLDSDGIFVSSSPFMISIENSG 353
Query: 350 IKVLPHIINVCILSSAWSSGNSFMYATTRSLLSLSQEGYAPKIFNRVNRWGVPYTGVAFA 409
KVLP I N +L + S+GNS +Y +R L SLS+ AP+ + V R GVPY V
Sbjct: 354 TKVLPDIFNAVVLITILSAGNSNVYIGSRVLYSLSKNSLAPRFLSNVTRGGVPYFSVLST 413
Query: 410 TAFSCLAYLNVSSSTADVFNWFSNISTISGFLGWICSGVAYLRFRKAVFFNNL-YDRLPF 468
+ F LA+L VS+ + FNW NI+ ++GF W+ +++RF +A+ + D LP+
Sbjct: 414 SVFGFLAFLEVSAGSGKAFNWLLNITGVAGFFAWLLISFSHIRFMQAIRKRGISRDDLPY 473
Query: 469 KTPFQPYFTWFYXXXXXXXXXXNGYESFV-HWNYKDFIAAYITLPLFLILWLGHKAYTRT 527
K P+ ++ G+ +F + DF+AAYI++ LFL +WL + + +
Sbjct: 474 KAQMMPFLAYYASFFIALIVLIQGFTAFAPTFQPIDFVAAYISIFLFLAIWLSFQVWFKC 533
Query: 528 WSQWMISVSEIDVTTGLREIEE 549
W + +ID+ + R+IEE
Sbjct: 534 RLLW--KLQDIDIDSDRRQIEE 553
>YEL063c [E] KOG1286 Amino acid transporters
Length = 590
Score = 319 bits (817), Expect = 8e-87
Identities = 181/520 (34%), Positives = 279/520 (52%), Gaps = 23/520 (4%)
Query: 52 LKKGLKSAHIQLIAIGGCIGTGLFVGTSSTLYKCGPAGLFISYCIMSTIIYPVMNALAEM 111
+K+ LK HI +IA+GG IGTGLF+G S+ L GP G ISY M ++ Y V +L EM
Sbjct: 84 VKRELKQRHIGMIALGGTIGTGLFIGLSTPLTNAGPVGALISYLFMGSLAYSVTQSLGEM 143
Query: 112 VCFLPGLPDENETGGSISTLCTRYVDSSLGFAVGWNYVYCYVILVAAECTAASGVVTYWT 171
F+P S + R++ + G A G+ Y + + I A E + V+ +WT
Sbjct: 144 ATFIP-------VTSSFTVFSQRFLSPAFGAANGYMYWFSWAITFALELSVVGQVIQFWT 196
Query: 172 TAVPKAAWITIFLGIIVVLNCTAVEFYGTSEAIFCSLKIFCILGIIIVSIVLFFGGGPNH 231
VP AAWI+IF II ++N V++YG E S+K+ I+G +I + G G
Sbjct: 197 YKVPLAAWISIFWVIITIMNLFPVKYYGEFEFWVASIKVLAIIGFLIYCFCMVCGAGVTG 256
Query: 232 DRLGFRFWKDPGAWAYHLA--DGGAGRLSDIITGVIRAGFAFILGPELVVLTSTEAQDSR 289
+GFR+W++PGAW + D GR ++ +I A F F G ELV +T+ EA + R
Sbjct: 257 P-VGFRYWRNPGAWGPGIISKDKNEGRFLGWVSSLINAAFTF-QGTELVGITAGEAANPR 314
Query: 290 RNIEKAARRFVWRLIFFYCVSSLCAGVIVSRNDPVLLNALSQGKPGAGSSPFVIGIQNAG 349
+++ +A ++ V+R++ FY S L G++V NDP L + S +SPF+I I+N+G
Sbjct: 315 KSVPRAIKKVVFRILTFYIGSLLFIGLLVPYNDPKLTQSTSY----VSTSPFIIAIENSG 370
Query: 350 IKVLPHIINVCILSSAWSSGNSFMYATTRSLLSLSQEGYAPKIFNRVNRWGVPYTGVAFA 409
KVLPHI N IL++ S+ NS +Y +R L LS+ APK +R + GVPY V
Sbjct: 371 TKVLPHIFNAVILTTIISAANSNIYVGSRILFGLSKNKLAPKFLSRTTKGGVPYIAVFVT 430
Query: 410 TAFSCLAYLNVSSSTADVFNWFSNISTISGFLGWICSGVAYLRFRKAVFFNNL-YDRLPF 468
AF LAY+ S+ VF W NI+ ++GF W+ ++++RF +A+ + + D LPF
Sbjct: 431 AAFGALAYMETSTGGDKVFEWLLNITGVAGFFAWLFISISHIRFMQALKYRGISRDELPF 490
Query: 469 KTPFQPYFTWFYXXXXXXXXXXNGYESFV-HWNYKDFIAAYITLPLFLILWLGHKAYTRT 527
K P ++ G+ +F +N F AAYI++ LFL +W+ + R
Sbjct: 491 KAKLMPGLAYYAATFMTIIIIIQGFTAFAPKFNGVSFAAAYISIFLFLAVWILFQCIFRC 550
Query: 528 WSQWMISVSEIDVTTGLREIEEETKELNARRIPPRNLWEK 567
W + ++D+ + R+IE E + P+ W+K
Sbjct: 551 RFIW--KIGDVDIDSDRRDIEAIVWEDH----EPKTFWDK 584
>SPCC777.04 [E] KOG1286 Amino acid transporters
Length = 521
Score = 314 bits (804), Expect = 3e-85
Identities = 164/474 (34%), Positives = 272/474 (56%), Gaps = 12/474 (2%)
Query: 51 NLKKGLKSAHIQLIAIGGCIGTGLFVGTSSTLYKCGPAGLFISYCIMSTIIYPVMNALAE 110
+LK+ KS H+ +I++ G IGTGL +G+ S L K GP LFI+Y + +Y V+ +L E
Sbjct: 41 SLKREFKSRHVNMISVAGAIGTGLVIGSGSALLKGGPGSLFIAYLMTGINLYVVLISLGE 100
Query: 111 MVCFLPGLPDENETGGSISTLCTRYVDSSLGFAVGWNYVYCYVILVAAECTAASGVVTYW 170
M F + S +RYVD +LGFA GWNY + Y I+ TA V+ YW
Sbjct: 101 MAAF-------SSDDKGFSGFSSRYVDKALGFATGWNYFFKYAIVYPTNLTAVGIVIHYW 153
Query: 171 TTAVPKAAWITIFLGIIVVLNCTAVEFYGTSEAIFCSLKIFCILGIIIVSIVLFFGGGPN 230
+ W+ +FL +I+ +N V+++G E ++KI ++ +II IV+ GG P
Sbjct: 154 RPDLNVGIWVAVFLVVILAINLLHVKYFGEVEFWLSAVKILVLVTLIITCIVITSGGTPV 213
Query: 231 HDRLGFRFWKDPGAWAYHLADGGAGRLSDIITGVIRAGFAFILGPELVVLTSTEAQDSRR 290
H ++GF +W+DPGA+A +L +G GR ++++ FA++ G E+V + EA + +
Sbjct: 214 HHKIGFHYWRDPGAFAPYLVEGSTGRFLGFWACLVQSCFAYV-GSEVVGIAFGEAPNPEK 272
Query: 291 NIEKAARRFVWRLIFFYCVSSLCAGVIVSRNDPVLLNALSQGKPGAGSSPFVIGIQNAGI 350
I K++ + ++R+ FY + G+ V + +L + S+G A +SPFV+ I+ A I
Sbjct: 273 TIRKSSFQSLFRIATFYVIGVFVLGLCVPYDSDILSSNASKG--NAAASPFVVAIKLAQI 330
Query: 351 KVLPHIINVCILSSAWSSGNSFMYATTRSLLSLSQEGYAPKIFNRVNRWGVPYTGVAFAT 410
KV+P +IN C+L SS NS +Y +R+L +L++EGYAPKI + G+P+ G +
Sbjct: 331 KVMPDVINACLLVFIISSANSDIYIGSRTLYALAKEGYAPKILMLQTKQGIPWVGCLVTS 390
Query: 411 AFSCLAYLNVSSSTADVFNWFSNISTISGFLGWICSGVAYLRFRKAVFFNNL-YDRLPFK 469
+F LA++N SS+A +F +FS+ T+ G + WI ++Y+ + +A + +R+PF+
Sbjct: 391 SFGLLAFMNTKSSSATIFGYFSSAVTVFGTINWINILLSYICYHRATIVQQIPTERIPFR 450
Query: 470 TPFQPYFTWFYXXXXXXXXXXNGYESFVH-WNYKDFIAAYITLPLFLILWLGHK 522
+ QPY + NGY +F+H + Y+ FI +YI + ++I+ LG K
Sbjct: 451 SWGQPYIAYASLIFTGLITFFNGYNAFIHGFKYRSFITSYIGIAAYVIMILGWK 504
>YKR039w [E] KOG1286 Amino acid transporters
Length = 602
Score = 303 bits (777), Expect = 4e-82
Identities = 172/503 (34%), Positives = 284/503 (56%), Gaps = 21/503 (4%)
Query: 52 LKKGLKSAHIQLIAIGGCIGTGLFVGTSSTLYKCGPAGLFISYCIMSTIIYPVMNALAEM 111
LK LK+ H+Q+IAIGG IGTGL VG+ + L GPA L I + T+IY ++ AL E+
Sbjct: 86 LKHHLKNRHLQMIAIGGAIGTGLLVGSGTALRTGGPASLLIGWGSTGTMIYAMVMALGEL 145
Query: 112 VCFLPGLPDENETGGSISTLCTRYVDSSLGFAVGWNYVYCYVILVAAECTAASGVVTYWT 171
P G +T TR++D S G+A +NY+ +++++ E +AS V +W
Sbjct: 146 AVIFP-------ISGGFTTYATRFIDESFGYANNFNYMLQWLVVLPLEIVSASITVNFWG 198
Query: 172 TAVP-KAAWITIFLGIIVVLNCTAVEFYGTSEAIFCSLKIFCILGIIIVSIVLFFGGGPN 230
T + ++ +F IV++N V+ YG +E +F +K+ ++G II+ I+L GGGP
Sbjct: 199 TDPKYRDGFVALFWLAIVIINMFGVKGYGEAEFVFSFIKVITVVGFIILGIILNCGGGPT 258
Query: 231 HDRLGFRFWKDPGAWAYHLADGGAGRLSDIITGVIRAGFAFILGPELVVLTSTEAQDSRR 290
+G ++W DPGA+A D + + + + A F+F G ELV L ++E+ + R+
Sbjct: 259 GGYIGGKYWHDPGAFA---GDTPGAKFKGVCSVFVTAAFSFA-GSELVGLAASESVEPRK 314
Query: 291 NIEKAARRFVWRLIFFYCVSSLCAGVIVSRNDPVLLNALSQGKPGAGSSPFVIGIQNAGI 350
++ KAA++ WR+ FY +S L G++V ND L+ A S A +SPFVI I+ GI
Sbjct: 315 SVPKAAKQVFWRITLFYILSLLMIGLLVPYNDKSLIGASSVD---AAASPFVIAIKTHGI 371
Query: 351 KVLPHIINVCILSSAWSSGNSFMYATTRSLLSLSQEGYAPKIFNRVNRWGVPYTGVAFAT 410
K LP ++NV IL + S GNS +YA +R++++L+++ + P+IF+ V+R G P G+A +
Sbjct: 372 KGLPSVVNVVILIAVLSVGNSAIYACSRTMVALAEQRFLPEIFSYVDRKGRPLVGIAVTS 431
Query: 411 AFSCLAYLNVSSSTADVFNWFSNISTISGFLGWICSGVAYLRFRKAVFFNNL-YDRLPFK 469
AF +A++ S +VFNW +S +S W + ++RFRKA+ D L FK
Sbjct: 432 AFGLIAFVAASKKEGEVFNWLLALSGLSSLFTWGGICICHIRFRKALAAQGRGLDELSFK 491
Query: 470 TPFQPYFTWFYXXXXXXXXXXNGYESFV----HWNYKDFIAAYITLPLFLILWLGHKAYT 525
+P + +++ Y + + + F AY++ PL +++++GHK Y
Sbjct: 492 SPTGVWGSYWGLFMVIIMFIAQFYVAVFPVGDSPSAEGFFEAYLSFPLVMVMYIGHKIYK 551
Query: 526 RTWSQWMISVSEIDVTTGLREIE 548
R W + I ++D+ TG RE++
Sbjct: 552 RNW-KLFIPAEKMDIDTGRREVD 573
>YBR132c [E] KOG1286 Amino acid transporters
Length = 596
Score = 283 bits (723), Expect = 6e-76
Identities = 162/512 (31%), Positives = 269/512 (51%), Gaps = 23/512 (4%)
Query: 53 KKGLKSAHIQLIAIGGCIGTGLFVGTSSTLYKCGPAGLFISYCIMSTIIYPVMNALAEMV 112
++ L++ H+QLIAI G IGT LFV LY+ GPA L +++ + I + + AEMV
Sbjct: 85 RRKLENRHVQLIAISGVIGTALFVAIGKALYRGGPASLLLAFALWCVPILCITVSTAEMV 144
Query: 113 CFLPGLPDENETGGSISTLCTRYVDSSLGFAVGWNYVYCYVILVAAECTAASGVVTYW-- 170
CF P L T+ VD SL WN+ + + + E + + ++ YW
Sbjct: 145 CFFP-------VSSPFLRLATKCVDDSLAVMASWNFWFLECVQIPFEIVSVNTIIHYWRD 197
Query: 171 --TTAVPKAAWITIFLGIIVVLNCTAVEFYGTSEAIFCSLKIFCILGIIIVSIVLFFGGG 228
+ +P A + ++L +++ AV++YG E S KI LG+ + + GG
Sbjct: 198 DYSAGIPLAVQVVLYL----LISICAVKYYGEMEFWLASFKIILALGLFTFTFITMLGGN 253
Query: 229 PNHDRLGFRFWKDPGAWAYHLADGGAGRLSDIITG----VIRAGFAFILGPELVVLTSTE 284
P HDR GFR + + Y G+ S G +I+A F I G E + + + E
Sbjct: 254 PEHDRYGFRNYGESPFKKYFPDGNDVGKSSGYFQGFLACLIQASFT-IAGGEYISMLAGE 312
Query: 285 AQDSRRNIEKAARRFVWRLIFFYCVSSLCAGVIVSRNDPVLLNALSQGKPGAGSSPFVIG 344
+ R+ + KA ++ RL F + S LC G++ S NDP L A+++ +PGAGSSP+VI
Sbjct: 313 VKRPRKVLPKAFKQVFVRLTFLFLGSCLCVGIVCSPNDPDLTAAINEARPGAGSSPYVIA 372
Query: 345 IQNAGIKVLPHIINVCILSSAWSSGNSFMYATTRSLLSLSQEGYAPKIFNRVNRWGVPYT 404
+ N I++LP I+N+ ++++A+S+GN++ Y ++R+ ++ +GYAPKIF R NR GVP
Sbjct: 373 MNNLKIRILPDIVNIALITAAFSAGNAYTYCSSRTFYGMALDGYAPKIFTRCNRHGVPIY 432
Query: 405 GVAFATAFSCLAYLNVSSSTADVFNWFSNISTISGFLGWICSGVAYLRFRKAVFF-NNLY 463
VA + ++ ++ L ++S++A V NW N+ T S + ++ + YL FR+A +
Sbjct: 433 SVAISLVWALVSLLQLNSNSAVVLNWLINLITASQLINFVVLCIVYLFFRRAYHVQQDSL 492
Query: 464 DRLPFKTPFQPYFTWFYXXXXXXXXXXNGYESFVH--WNYKDFIAAYITLPLFLILWLGH 521
+LPF++ QPY GY F WN +DF+ +Y+ + + + +++G+
Sbjct: 493 PKLPFRSWGQPYTAIIGLVSCSAMILIQGYTVFFPKLWNTQDFLFSYLMVFINIGIYVGY 552
Query: 522 KAYTRTWSQWMISVSEIDVTTGLREIEEETKE 553
K + + EID + L EIE E
Sbjct: 553 KFIWKRGKDHFKNPHEIDFSKELTEIENHEIE 584
>YGR191w [E] KOG1286 Amino acid transporters
Length = 603
Score = 282 bits (721), Expect = 1e-75
Identities = 161/523 (30%), Positives = 270/523 (50%), Gaps = 20/523 (3%)
Query: 32 SNDSEKNGSLPNKPQSGDHNLKKGLKSAHIQLIAIGGCIGTGLFVGTSSTLYKCGPAGLF 91
S+D + + + NL K L H+ +A+GG IGTGL+V T + L GPA L
Sbjct: 66 SSDRFRRNEDTEQEDINNTNLSKDLSVRHLLTLAVGGAIGTGLYVNTGAALSTGGPASLV 125
Query: 92 ISYCIMSTIIYPVMNALAEMVCFLPGLPDENETGGSISTLCTRYVDSSLGFAVGWNYVYC 151
I + I+ST ++ V+N+L E+ P + G + R+++ S FAV NY+
Sbjct: 126 IDWVIISTCLFTVINSLGELSAAFPVV-------GGFNVYSMRFIEPSFAFAVNLNYLAQ 178
Query: 152 YVILVAAECTAASGVVTYWTTAVPKAAWITIFLGIIVVLNCTAVEFYGTSEAIFCSLKIF 211
+++L+ E AAS + YW + AW+ IF I + N V+ +G +E + +KI
Sbjct: 179 WLVLLPLELVAASITIKYWNDKINSDAWVAIFYATIALANMLDVKSFGETEFVLSMIKIL 238
Query: 212 CILGIIIVSIVLFFGGGPNHDRLGFRFWKDPGAWAYHLADGGAGRLSDIITGVIRAGFAF 271
I+G I+ IVL GGGP+ +G ++W DPGA+ H + + + + A F++
Sbjct: 239 SIIGFTILGIVLSCGGGPHGGYIGGKYWHDPGAFVGH---SSGTQFKGLCSVFVTAAFSY 295
Query: 272 ILGPELVVLTSTEAQDSRRNIEKAARRFVWRLIFFYCVSSLCAGVIVSRNDPVLLNALSQ 331
G E+ +++ E+++ R I KAA+R W + Y G +V NDP LLN S
Sbjct: 296 -SGIEMTAVSAAESKNPRETIPKAAKRTFWLITASYVTILTLIGCLVPSNDPRLLNGSS- 353
Query: 332 GKPGAGSSPFVIGIQNAGIKVLPHIINVCILSSAWSSGNSFMYATTRSLLSLSQEGYAPK 391
A SSP VI I+N GIK LP ++N IL + S NS +YA +R +++++ G PK
Sbjct: 354 -SVDAASSPLVIAIENGGIKGLPSLMNAIILIAVVSVANSAVYACSRCMVAMAHIGNLPK 412
Query: 392 IFNRVNRWGVPYTGVAFATAFSCLAYLNVSSSTADVFNWFSNISTISGFLGWICSGVAYL 451
NRV++ G P + F L+++ S A+VF W S +S +S W+ ++++
Sbjct: 413 FLNRVDKRGRPMNAILLTLFFGLLSFVAASDKQAEVFTWLSALSGLSTIFCWMAINLSHI 472
Query: 452 RFRKAV-FFNNLYDRLPFKTPFQPYFTWFYXXXXXXXXXXNGYESFVHW-----NYKDFI 505
RFR+A+ D LPF + +W+ + + S + + F
Sbjct: 473 RFRQAMKVQERSLDELPFISQTGVKGSWYGFIVLFLVLIASFWTSLFPLGGSGASAESFF 532
Query: 506 AAYITLPLFLILWLGHKAYTRTWSQWMISVSEIDVTTGLREIE 548
Y++ P+ ++ ++GHK YTR W+ M+ + ++D+ TG ++++
Sbjct: 533 EGYLSFPILIVCYVGHKLYTRNWT-LMVKLEDMDLDTGRKQVD 574
>SPBC19F8.06c [E] KOG1286 Amino acid transporters
Length = 574
Score = 259 bits (662), Expect = 8e-69
Identities = 159/520 (30%), Positives = 266/520 (50%), Gaps = 30/520 (5%)
Query: 41 LPNKPQSGDHNLKKGLKSAHIQLIAIGGCIGTGLFVGTSSTLYKCGPAGLFISYCIMSTI 100
+P +P+ +L++ LK H+Q+IAIGGC+GTGLFVG+ + L GPA + I++ ++ T
Sbjct: 48 VPLQPED-TQDLQRKLKPRHMQMIAIGGCVGTGLFVGSGNALADGGPASILIAFAVIGTY 106
Query: 101 IYPVMNALAEMVCFLPGLPDENETGGSISTLCTRYVDSSLGFAVGWNYVYCYVILVAAEC 160
+ +ALAE+ P GS T ++++D + GFAVG Y + + V E
Sbjct: 107 VLFTTSALAELSAIYP-------VSGSFYTYFSKFIDPAWGFAVGIQYWLSFAVTVPLEL 159
Query: 161 TAASGVVTYWTTAVPKAAWITIFLGIIVVLNCTAVEFYGTSEAIFCSLKIFCILGIIIVS 220
T A ++ +W + P + WI++F II+ +N E YG E +K+ ++G +I+S
Sbjct: 160 TVAPLIINFWNASGPVSIWISVFYVIIIAINIWGTEGYGEVEFFLSIMKVISVIGFVILS 219
Query: 221 IVLFFGGGPNHDR--LGFRFWKDPGAWAYHLADGGAGRLSDIITGVIRAGFAFILGPELV 278
I++ GG P DR +G +WK P + +G G + + + + G ELV
Sbjct: 220 IIIAAGGVPTDDRGVIGVSYWKQPLVFN----NGFKGLCAVSVIAIFS-----LSGTELV 270
Query: 279 VLTSTEAQDSRRNIEKAARRFVWRLIFFYCVSSLCAGVIVSRNDPVLLNALSQGKPGAGS 338
L ++EA++ ++ + A ++ WR+ FY V+ ++V + P L +
Sbjct: 271 GLAASEAKNPQKTVPAAVKQIFWRIFLFYIVALFMLTLVVPSDLPGLRTS---DNSNVLI 327
Query: 339 SPFVIGIQNAGIKVLPHIINVCILSSAWSSGNSFMYATTRSLLSLSQEGYAPKIFNRVNR 398
SPFVI IQ A I+ LP I+NV IL S S GNS YA +R+L +L++ GYAPKIFN+ N+
Sbjct: 328 SPFVIAIQLANIRALPSIMNVVILLSTLSVGNSASYAASRALFALAKNGYAPKIFNKTNK 387
Query: 399 WGVPYTGVAFATAFSCLAYLNVSSSTADVFNWFSNISTISGFLGWICSGVAYLRFRKA-V 457
G P +A F +AY + +F W +I +S W +A+++FR+A
Sbjct: 388 RGHPIYAIAVTLLFGSIAYFTEAGVGGALFGWLLSICGLSTTFIWGSICLAHIQFRRAWK 447
Query: 458 FFNNLYDRLPFKTPFQPYFTWFYXXXXXXXXXXNGYESFVHWNYK----DFIAAYITLPL 513
N + LP+++ F Y + + Y + K DF AY+ P+
Sbjct: 448 IQNRKLEDLPYRSIFGVYGSIYGVAMTILALIAQFYVAVFPIGKKPNPVDFFQAYMAAPI 507
Query: 514 FLILWLGHKAYTRTWSQWMISVSEIDVTTGLREIEEETKE 553
+I ++ K + RT + + +ID++ G +++ E
Sbjct: 508 LIISFVAWKFFRRT---SFVRIEKIDLSEGAHGEQKQNLE 544
>SPCC965.11c [E] KOG1286 Amino acid transporters
Length = 537
Score = 255 bits (652), Expect = 1e-67
Identities = 162/505 (32%), Positives = 255/505 (50%), Gaps = 32/505 (6%)
Query: 46 QSGDHNLKKGLKSAHIQLIAIGGCIGTGLFVGTSSTLYKCGPAGLFISYCIMSTIIYPVM 105
++ + +K+GLK+ H+ ++A+ G IG G+F+G S L+ GP GL + + I+S +++ VM
Sbjct: 34 ENNSNGIKRGLKTRHVSMMALAGIIGPGVFIGMGSALHIGGPVGLIVGFAIVSIVVFGVM 93
Query: 106 NALAEMVCFLPGLPDENETGGSISTLCTRYVDSSLGFAVGWNYVYCYVILVAAECTAASG 165
++ E L D N +T R+VD + G A+GWNYV ++ +AAE T+ +
Sbjct: 94 LSIGEF----NSLFDFN-----FNTHAARWVDPAFGAAIGWNYVIVWLTNIAAEYTSLTS 144
Query: 166 VVTYWTTAVPKAAWITIFLGIIVVLNCTAVEFYGTSEAIFCSLKIFCILGIIIVSIVLFF 225
++ YW VP + IF G V +G SE I +K+ I G I +I+
Sbjct: 145 ILQYWGPHVPSYGFFLIFWGFFTCYQMLGVSVFGESEYILAFIKLLFITGFYIFAIIYAA 204
Query: 226 GGGPNHDRLGFRFWKDPGAWA-YHLADGGAGRLSDIITGVIRAGFAFILGPELVVLTSTE 284
GG P+H K P + LA G G I++ + AG F G E V +T+ E
Sbjct: 205 GGIPHH--------KPPNLFKEMPLAHGFGG----IVSAFVYAG-VFFSGVESVSMTAAE 251
Query: 285 AQDSRRNIEKAARRFVWRLIFFYCVSSLCAGVIVSRNDPVLLNALSQGKPGAGSSPFVIG 344
+++ ++ I A R+ WR+++ Y S+ G+ V+ NDP L + K SP I
Sbjct: 252 SKNPKKAIPLAVRQTFWRILYVYFGISISYGITVAWNDPNLSSGSKTLK-----SPMTIA 306
Query: 345 IQNAGIKVLPHIINVCILSSAWSSGNSFMYATTRSLLSLSQEGYAPKIFNRVNRWGVPYT 404
I NAG +N IL + SS NS +Y +RSL +L+++G APKIF RV++ GVP+
Sbjct: 307 IMNAGWNHAGDFVNAVILITCLSSINSGIYIGSRSLYNLAKDGMAPKIFKRVDKRGVPWV 366
Query: 405 GVAFATAFSCLAYLNVSSSTADVFNWFSNISTISGFLGWICSGVAYLRFRKA-VFFNNLY 463
V F L+ +N S+ + + N++ +S F+ W + RFR+ V
Sbjct: 367 AVHSVHLFGFLSIMNYSTGAVKAYGYIINLAGVSAFIVWTAIIFVHFRFRRGWVKQGYAL 426
Query: 464 DRLPFKTPFQPYFTWFYXXXXXXXXXXNGYESFVHWNYKDFIAAYITLPLFLILWLGHKA 523
LPFK+P P+ G+ F + DF+ AYI LPLF ++WL +K
Sbjct: 427 SDLPFKSPLYPFPQLIGFVIGIILTLVQGWTVFKPFAAGDFVDAYILLPLFFVIWLSYKF 486
Query: 524 YTRTWSQWMISVSEIDVTTGLREIE 548
+T +W +S ++D G R IE
Sbjct: 487 IKKT--KW-VSYEDMDFINGRRVIE 508
>SPAP7G5.06 [E] KOG1286 Amino acid transporters
Length = 583
Score = 255 bits (652), Expect = 1e-67
Identities = 177/545 (32%), Positives = 269/545 (48%), Gaps = 38/545 (6%)
Query: 21 GQVYELDLTSYSNDSEKNGSLPNKPQSGDHN----LKKGLKSAHIQLIAIGGCIGTGLFV 76
G+V D S+ N +K S KP D LK+ LK H+Q+IAIGG IGTGLFV
Sbjct: 46 GEVEYADTPSHQNFLQKFFS-DFKPVKADREDGVALKRHLKGRHMQMIAIGGAIGTGLFV 104
Query: 77 GTSSTLYKCGPAGLFISYCIMSTIIYPVMNALAEMVCFLPGLPDENETGGSISTLCTRYV 136
G+ S+L GPA + I Y ++ +++ + AL E+ P G R++
Sbjct: 105 GSGSSLADGGPASVIIDYTLIGIMMFFTVYALGELAVSYP-------VAGGFYNYAVRFI 157
Query: 137 DSSLGFAVGWNYVYCYVILVAAECTAASGVVTYWTTAVPKAAWITIFLGIIVVLNCTAVE 196
D + GFAVGWNY Y + E T + YWT + AWITIFL ++ +N V
Sbjct: 158 DPAWGFAVGWNYFMNYFVTFPLELTTCAITFRYWTD-INSCAWITIFLVFVICINLFGVR 216
Query: 197 FYGTSEAIFCSLKIFCILGIIIVSIVLFFGGGPNHDR--LGFRFWKDPGAWAYHLADGGA 254
YG E I +LK+ G II++I++ GG P R +G + K+
Sbjct: 217 GYGEVEFILSTLKVVATTGFIILAIIINCGGVPTDPRGYIGGKIIKNK-----PFRHSFK 271
Query: 255 GRLSDIITGVIRAGFAFILGPELVVLTSTEAQDSRRNIEKAARRFVWRLIFFYCVSSLCA 314
G S T AGF+F G E+V L + EA+D ++++ +A ++ WR+ FY VS +
Sbjct: 272 GFCSVFTT----AGFSF-SGTEVVGLAAAEAEDPQKSLPRATKQVFWRIAIFYVVSLILI 326
Query: 315 GVIVSRNDPVLLNALSQGKPGAGSSPFVIGIQNAGIKVLPHIINVCILSSAWSSGNSFMY 374
G++VS +DP L+ S G +SPFV+ I+ A I+ LP + N I+ S S NS +
Sbjct: 327 GLLVSPDDPRLMGNSSDG----STSPFVLAIKEANIRGLPSVFNAVIIISTVSVANSCTF 382
Query: 375 ATTRSLLSLSQEGYAPKIFNRVNRWGVPYTGVAFATAFSCLAYLNVSSSTAD-VFNWFSN 433
+R+L +++ +G AP+ F +R G P +A F AY+N + +D VF+W
Sbjct: 383 TASRTLHAMAAKGDAPRFFAYTDRLGRPLLAMAVCLLFGFFAYINAAGDVSDTVFDWLLA 442
Query: 434 ISTISGFLGWICSGVAYLRFRKAV-FFNNLYDRLPFKTPFQPYFTWFYXXXXXXXXXXNG 492
IS IS F W + ++ FR A+ D+L F +P + +
Sbjct: 443 ISGISNFFSWGSINLCHIVFRLAMKKQGRSLDQLGFVSPMGIWGSAIGLAFNILCLMAEF 502
Query: 493 YESFV----HWNYKDFIAAYITLPLFLILWLGHKAYTRTWSQWMISVSEIDVTTGLREIE 548
Y S N DF Y+ P+ + ++G+K Y R+ + S+S++D+ TGLR
Sbjct: 503 YVSLFPIGSKPNANDFFQGYLAAPIVIAFFIGYKIYDRS---HIPSLSKLDLDTGLRTYP 559
Query: 549 EETKE 553
+ KE
Sbjct: 560 PKDKE 564
>SPBPB2B2.01 [E] KOG1286 Amino acid transporters
Length = 585
Score = 255 bits (651), Expect = 1e-67
Identities = 167/533 (31%), Positives = 263/533 (49%), Gaps = 39/533 (7%)
Query: 43 NKPQSGDHNLKKGLKSAHIQLIAIGGCIGTGLFVGTSSTLYKCGPAGLFISYCIMSTIIY 102
N+ S LK+ LKS HIQ+I IGG IGTG++VG+S +LY+ G A + I YCI+ T+++
Sbjct: 70 NQQDSAGQGLKRRLKSRHIQMIGIGGAIGTGVWVGSSKSLYRGGAASVLIDYCIVGTMVF 129
Query: 103 PVMNALAEMVCFLPGLPDENETGGSISTLCTRYVDSSLGFAVGWNYVYCYVILVAAECTA 162
+ AL E+ P T GS T TR++D S GFA+ WNYV+ +++ + E T
Sbjct: 130 CTVYALGELAVAFP-------TRGSFVTHATRFIDESWGFALSWNYVFSFIVTIPLELTT 182
Query: 163 ASGVVTYWTTAVPKAAWITIFLGIIVVLNCTAVEFYGTSEAIFCSLKIFCILGIIIVSIV 222
+ ++ YWT + W+T+F+ + +N V+ YG E I ++K+ + G II+ I+
Sbjct: 183 GTMMIKYWTN-LNSGIWVTVFIVFLFFINIFGVKGYGEMEFIMSTIKVVAMCGFIILGII 241
Query: 223 LFFGGGPNHDRLGFRFWKDPGAWAYHLADGGAGR--LSDIITGVIRAGFAFILGPELVVL 280
+ GG P R G H+ A R A F+F G E V +
Sbjct: 242 IDCGGVPTDHR---------GYMGTHIFRENAFRHKFKGFCAVFTSAAFSFS-GTEYVGV 291
Query: 281 TSTEAQDSRRNIEKAARRFVWRLIFFYCVSSLCAGVIVSRNDPVLLNALSQGKPGAGSSP 340
+ E ++ + A R+ ++R+ FY +S +++S DP L + G +SP
Sbjct: 292 AAAETENPAKAFPVAVRQTLFRIAIFYILSLFIVSLLISGADPRLTSY-----HGVDASP 346
Query: 341 FVIGIQNAGIKVLPHIINVCILSSAWSSGNSFMYATTRSLLSLSQEGYAPKIFNRVNRWG 400
FV+ I++A IK LP I+N IL S SS N+ +YA +R++ SL G+APK F V+R G
Sbjct: 347 FVLAIKDANIKALPSILNAIILISVISSANAQLYAGSRAIHSLGCNGFAPKCFTLVDREG 406
Query: 401 VPYTGVAFATAFSCLAYLNVSSSTADVFNWFSNISTISGFLGWICSGVAYLRFRKAV-FF 459
P + F L YL + VF+W +IS + W +A++R+R A+
Sbjct: 407 RPLVALLILFLFMFLGYLVETGQYDTVFDWMLSISGLGTLFCWGSICLAHIRYRAAMKHQ 466
Query: 460 NNLYDRLPFKTPFQPYFTWFYXXXXXXXXXXNGYESFVHWNYKD----FIAAYITLPLFL 515
N + F +PF Y +++ Y S K F Y++ P+ L
Sbjct: 467 NRSLKEVGFVSPFNVYASYYAFILVCLVLAAEFYVSIFPVGGKPDASAFFENYLSAPVIL 526
Query: 516 ILWLGHKAYTRTWSQWMISVSEIDVTTG------LREIEEETKELNARRIPPR 562
+ ++ HK Y +T I++S +D+ T + E EEE K + I R
Sbjct: 527 VFFICHKLYYKT---KRITLSNMDLETDFAYKTPVEEEEEEEKSAGSLSIKQR 576
>YCL025c [E] KOG1286 Amino acid transporters
Length = 595
Score = 251 bits (640), Expect = 3e-66
Identities = 156/519 (30%), Positives = 256/519 (49%), Gaps = 31/519 (5%)
Query: 27 DLTSYSNDSEKNGSLPNKPQSGDH----------NLKKGLKSAHIQLIAIGGCIGTGLFV 76
DLTS + S + K +S D+ +LKK ++ H+ +IA+G IGTGL V
Sbjct: 81 DLTSAISPSSRQAQELEKNESSDNIGANTGHKSDSLKKTIQPRHVLMIALGTGIGTGLLV 140
Query: 77 GTSSTLYKCGPAGLFISYCIMSTIIYPVMNALAEMVCFLPGLPDENETGGSISTLCTRYV 136
G + L GPAGL I Y IM +I+Y ++ A EM L N TGG + + V
Sbjct: 141 GNGTALVHAGPAGLLIGYAIMGSILYCIIQACGEMA-----LVYSNLTGG-YNAYPSFLV 194
Query: 137 DSSLGFAVGWNYVYCYVILVAAECTAASGVVTYWTTAVPKAAWITIFLGIIVVLNCTAVE 196
D GFAV W Y ++ + E AS + YWTT+V ++ IF +++ +N
Sbjct: 195 DDGFGFAVAWVYCLQWLCVCPLELVTASMTIKYWTTSVNPDVFVIIFYVLVITINIFGAR 254
Query: 197 FYGTSEAIFCSLKIFCILGIIIVSIVLFFGGGPNHDRLGFRFWKDPGAW-AYHLADGGAG 255
Y +E F KI + G I+ I++ GG N +G ++W DPGA+ H D
Sbjct: 255 GYAEAEFFFNCCKILMMTGFFILGIIIDVGGAGNDGFIGGKYWHDPGAFNGKHAID---- 310
Query: 256 RLSDIITGVIRAGFAFILGPELVVLTSTEAQDSRRNIEKAARRFVWRLIFFYCVSSLCAG 315
R + ++ A FAF G E + +T+ E + R+ I AA++ ++R++F + + + G
Sbjct: 311 RFKGVAATLVTAAFAFG-GSEFIAITTAEQSNPRKAIPGAAKQMIYRILFLFLATIILLG 369
Query: 316 VIVSRNDPVLLNALSQGKPGAGSSPFVIGIQNAGIKVLPHIINVCILSSAWSSGNSFMYA 375
+V N LL + G +SP+VI + + G++V+PH IN IL S S NS Y+
Sbjct: 370 FLVPYNSDQLLGSTGGGTK---ASPYVIAVASHGVRVVPHFINAVILLSVLSMANSSFYS 426
Query: 376 TTRSLLSLSQEGYAPKIFNRVNRWGVPYTGVAFATAFSCLAYLNVSSSTADVFNWFSNIS 435
+ R L+LS++GYAPK+F+ ++R G P + + F+ +A+ S VF W IS
Sbjct: 427 SARLFLTLSEQGYAPKVFSYIDRAGRPLIAMGVSALFAVIAFCAASPKEEQVFTWLLAIS 486
Query: 436 TISGFLGWICSGVAYLRFRKAV-FFNNLYDRLPFKTPFQPYFTWFYXXXXXXXXXXNGYE 494
+S W +++LRFR+A+ L FK+ + + + +
Sbjct: 487 GLSQLFTWTAICLSHLRFRRAMKVQGRSLGELGFKSQTGVWGSAYACIMMILILIAQFWV 546
Query: 495 SFV-----HWNYKDFIAAYITLPLFLILWLGHKAYTRTW 528
+ + + F Y+ +P+ + L++G+K + + W
Sbjct: 547 AIAPIGEGKLDAQAFFENYLAMPILIALYVGYKVWHKDW 585
>YPL274w [E] KOG1286 Amino acid transporters
Length = 587
Score = 247 bits (631), Expect = 3e-65
Identities = 172/585 (29%), Positives = 279/585 (47%), Gaps = 60/585 (10%)
Query: 25 ELDLTSYSNDSEKNGSLPNK-----PQSGDHNLKKGLKSA-------------------- 59
E + T+ NDS+++GSL + QS H + + L+++
Sbjct: 17 ETESTTIPNDSDRSGSLIRRMKDSFKQSNLHVIPEDLENSEQTEQEKIQWKLASQPYQKV 76
Query: 60 ----HIQLIAIGGCIGTGLFVGTSSTLYKCGPAGLFISYCIMSTIIYPVMNALAEMVCFL 115
H+ +IAIGG +GTGLF+G +L GPA L I + ++ T ++ V+ + AE+ C
Sbjct: 77 LSQRHLTMIAIGGTLGTGLFIGLGYSLAS-GPAALLIGFLLVGTSMFCVVQSAAELSCQF 135
Query: 116 PGLPDENETGGSISTLCTRYVDSSLGFAVGWNYVYCYVILVAAECTAASGVVTYWTTAVP 175
P GS +T +R++D S+GF V NY ++I +E + ++YW V
Sbjct: 136 P-------VSGSYATHVSRFIDESVGFTVATNYALAWLISFPSELIGCALTISYWNQTVN 188
Query: 176 KAAWITIFLGIIVVLNCTAVEFYGTSEAIFCSLKIFCILGIIIVSIVLFFGGGPNH-DRL 234
A W+ IF I+VLN V + +E +K+ I II+ IVL GGGPN +
Sbjct: 189 PAVWVAIFYVFIMVLNLFGVRGFAETEFALSIIKVIAIFIFIIIGIVLIAGGGPNSTGYI 248
Query: 235 GFRFWKDPGAWAYHLADGGAGRLSDIITGVIRAGFAFILGPELVVLTSTEAQDSRRNIEK 294
G ++W DPGA+A + ++ + A F+F G ELV+LTSTE+++ I +
Sbjct: 249 GAKYWHDPGAFAKPV-------FKNLCNTFVSAAFSF-GGSELVLLTSTESKNISA-ISR 299
Query: 295 AARRFVWRLIFFYCVSSLCAGVIVSRNDPVLLNALSQGKPGAGSSPFVIGIQNAGI--KV 352
AA+ WR+ FY + + G +V NDP LL+ +SPFVI + N G
Sbjct: 300 AAKGTFWRIAIFYITTVVIIGCLVPYNDPRLLS--GSNSEDVSASPFVIALSNTGSMGAK 357
Query: 353 LPHIINVCILSSAWSSGNSFMYATTRSLLSLSQEGYAPKIFNRVNRWGVPYTGVAFATAF 412
+ + +NV IL + S NS +YA++R + +L G P + + ++R G P G+ + AF
Sbjct: 358 VSNFMNVVILVAVVSVCNSCVYASSRLIQALGASGQLPSVCSYMDRKGRPLVGIGISGAF 417
Query: 413 SCLAYLNVSSSTADVFNWFSNISTISGFLGWICSGVAYLRFRKAV-FFNNLYDRLPFKTP 471
L +L S +VF W + +IS F W C ++ +RFR A+ D + +K+
Sbjct: 418 GLLGFLVASKKEDEVFTWLFALCSISSFFTWFCICMSQIRFRMALKAQGRSNDEIAYKSI 477
Query: 472 FQPYFTWFYXXXXXXXXXXNGYESFVHWNYKDFIAAY----ITLPLFLILWLGHKAYTRT 527
Y Y S A+ +++P+ ++++ H+ Y R
Sbjct: 478 LGVYGGILGCVLNALLIAGEIYVSAAPVGSPSSAEAFFEYCLSIPIMIVVYFAHRFYRRD 537
Query: 528 WSQWMISVSEIDVTTGLR----EIEEETKELNARRIPPRNLWEKI 568
W + I SEID+ TG E+ + KE + I + + KI
Sbjct: 538 WKHFYIKRSEIDLDTGCSVENLELFKAQKEAEEQLIASKPFYYKI 582
>YDR508c [E] KOG1286 Amino acid transporters
Length = 663
Score = 247 bits (630), Expect = 4e-65
Identities = 157/578 (27%), Positives = 280/578 (48%), Gaps = 35/578 (6%)
Query: 11 GETSVVDKQTGQVYELDLTSYSNDSEKNG--SLPNKPQSGDHNLKKGLKSAHIQLIAIGG 68
G T + K + + +L S+ +G P + + NLKK +K H ++++G
Sbjct: 102 GTTPISTKDSSSQLDNELNRKSSYITVDGIKQSPQEQEQKQENLKKSIKPRHTVMMSLGT 161
Query: 69 CIGTGLFVGTSSTLYKCGPAGLFISYCIMSTIIYPVMNALAEMVCFLPGLPDENETGGSI 128
IGTGL VG S L GP GL I Y IM + +Y ++ A E+ L G
Sbjct: 162 GIGTGLLVGNSKVLNNAGPGGLIIGYAIMGSCVYCIIQACGELAVIYSDLI------GGF 215
Query: 129 STLCTRYVDSSLGFAVGWNYVYCYVILVAAECTAASGVVTYWTTAVPKAAWITIFLGIIV 188
+T VD +LGF+V W + ++ + E AS + YWTT+V ++ IF +IV
Sbjct: 216 NTYPLFLVDPALGFSVAWLFCLQWLCVCPLELVTASMTIKYWTTSVNPDVFVVIFYVLIV 275
Query: 189 VLNCTAVEFYGTSEAIFCSLKIFCILGIIIVSIVLFFGGGPNHDRLGFRFWKDPGAWAYH 248
V+N + Y ++ F KI I+G I++I++ GG +G ++W+DPGA+
Sbjct: 276 VINVFGAKGYAEADFFFNCCKILMIVGFFILAIIIDCGGAGTDGYIGSKYWRDPGAFR-- 333
Query: 249 LADGGAGRLSDIITGVIRAGFAFILGPELVVLTSTEAQDSRRNIEKAARRFVWRLIFFYC 308
D R ++ + A FAF + +L +T++E + R+ I AA++ ++R++F +
Sbjct: 334 -GDTPIQRFKGVVATFVTAAFAFGMSEQLA-MTASEQSNPRKAIPSAAKKMIYRILFVFL 391
Query: 309 VSSLCAGVIVSRNDPVLLNALSQGKPGAGSSPFVIGIQNAGIKVLPHIINVCILSSAWSS 368
S G +V LL A +SP+VI + + G++V+PH IN IL S S
Sbjct: 392 ASLTLVGFLVPYTSDQLLGAAGSATK---ASPYVIAVSSHGVRVVPHFINAVILLSVLSV 448
Query: 369 GNSFMYATTRSLLSLSQEGYAPKIFNRVNRWGVPYTGVAFATAFSCLAYLNVSSSTADVF 428
N Y ++R L+SL+++G APK F+ ++R G P + + F +A+ S DVF
Sbjct: 449 ANGAFYTSSRILMSLAKQGNAPKCFDYIDREGRPAAAMLVSALFGVIAFCASSKKEEDVF 508
Query: 429 NWFSNISTISGFLGWICSGVAYLRFRKAV-FFNNLYDRLPFKTPFQPYFTWFYXXXXXXX 487
W IS +S WI ++++RFR+A+ + +K+ + + +
Sbjct: 509 TWLLAISGLSQLFTWITICLSHIRFRRAMKVQGRSLGEVGYKSQVGVWGSAYAVLMMVLA 568
Query: 488 XXXNGYESFV------HWNYKDFIAAYITLPLFLILWLGHKAYTRTWSQWMISVSEIDVT 541
+ + + + F Y+ +P+++ L++ +K + + WS + I ++D+
Sbjct: 569 LIAQFWVAIAPIGGGGKLSAQSFFENYLAMPIWIALYIFYKVWKKDWSLF-IPADKVDLV 627
Query: 542 TG--------LREIEEETKELNARRIPPRNLWEKILEW 571
+ L++ +EE KE R+ W+++L++
Sbjct: 628 SHRNIFDEELLKQEDEEYKE----RLRNGPYWKRVLDF 661
>SPBC1652.02 [E] KOG1286 Amino acid transporters
Length = 593
Score = 244 bits (624), Expect = 2e-64
Identities = 156/530 (29%), Positives = 266/530 (49%), Gaps = 44/530 (8%)
Query: 50 HNLKKGLKSAHIQLIAIGGCIGTGLFVGTSSTLYKCGPAGLFISYCIMSTIIYPVMNALA 109
HN + LK H+Q+IAIG CIGTGLFV T +L GP L I++ I+S +I ++ +L
Sbjct: 63 HNSEDFLKPRHLQMIAIGSCIGTGLFVSTGKSLKNAGPGSLMINFIILSAMILALILSLG 122
Query: 110 EMVCFLPGLPDENETGGSISTLCTRYVDSSLGFAVGWNYVYCYVILVAAECTAASGVVTY 169
EM CFLP SI+ R +++++GFA W Y + ++ ++ +E +AA VV +
Sbjct: 123 EMCCFLPNQ-------SSITMYTGRLLNNNIGFAQSWLYFWIWLTVLPSEISAACEVVDF 175
Query: 170 WTTA-VPKAAWITIFLGIIVVLNCTAVEFYGTSEAIFCSLKIFCILGIIIVSIVLFFGGG 228
WTT + A W+TIFL +V++N YG E + LK+ ++ V+I++ G
Sbjct: 176 WTTQHLNPAIWVTIFLAYVVLVNAFGARSYGECEFVSSFLKVVIVIIFFFVAIIINCGAA 235
Query: 229 PNHDRLGFRFWKDPGAWAYHLADGGAGRLSDIITGVIRAGFAFILGPELVVLTSTEAQDS 288
P +G +W PG++ +G G S I+ + G E + + +
Sbjct: 236 PKGGYIGAHYWHHPGSFR----NGFKGFCSVFISSAYS-----LSGTENIGTAAGNTSNP 286
Query: 289 RRNIEKAARRFVWRLIFFYCVSSLCAGVIVSRNDPVLLNALSQGKPGAGSSPFVIGIQNA 348
+R I A ++ +R+ FFY ++ ++V ++P L N SPF+I I+N
Sbjct: 287 QRAIPSAVKKVFYRMGFFYIITIFLITLVVPYDNPDLGNV----------SPFIIAIKNG 336
Query: 349 GIKVLPHIINVCILSSAWSSGNSFMYATTRSLLSLSQEGYAPKIFNRVNRWGVPYTGVAF 408
GI VLPHI N IL S S GN+ ++A +R+ ++L ++G+AP+ RV++ G P
Sbjct: 337 GIHVLPHITNAVILVSVLSVGNAAVFAASRNAMALVKQGWAPRFLGRVDQKGRPVISYLC 396
Query: 409 ATAFSCLAYLNVSSSTADVFNWFSNISTISGFLGWICSGVAYLRFRKAVFFNNLYDR-LP 467
+ A +C+AY+N + + VF+W ++S F+ W S + ++R R A+ + D LP
Sbjct: 397 SLAMACIAYVNAAPDGSVVFDWLMSVSGGGAFVIWGLSFIDHIRLRYAMKAQKIPDTVLP 456
Query: 468 FKTPFQPYFTWFYXXXXXXXXXXNGYESFVHWNYK-----DFIAAYITLPLFLILWLGHK 522
+K P Y +++ Y S ++ F +++ +F+ L
Sbjct: 457 YKFPGSVYLSYYGVLINFLALCALVYISIFPVTHEKPSAYGFFVSFLGPSVFIAYLLISP 516
Query: 523 AYTRTWSQWMISVSEIDVTTGLREI--------EEETKELNARRIPPRNL 564
+ + Q S+ ++D+TTG ++ E T EL+ + + NL
Sbjct: 517 IFVKPTFQ---SLKDVDLTTGRYDLVNSQMYVAESSTSELSEKDLTKPNL 563
>YOL020w [E] KOG1286 Amino acid transporters
Length = 592
Score = 243 bits (620), Expect = 6e-64
Identities = 158/515 (30%), Positives = 262/515 (50%), Gaps = 41/515 (7%)
Query: 51 NLKKGLKSAHIQLIAIGGCIGTGLFVGTSSTLYKCGPAGLFISYCIMSTIIYPVMNALAE 110
NLK+ LK H+ +IAIGG IGTGLFVG+ + + GP G+ I + I + I ++ L E
Sbjct: 77 NLKRTLKPRHLIMIAIGGSIGTGLFVGSGKAIAEGGPLGVVIGWAIAGSQIIGTIHGLGE 136
Query: 111 MVCFLPGLPDENETGGSISTLCTRYVDSSLGFAVGWNYVYCYVILVAAECTAASGVVTYW 170
+ P + G+ + TR++D S+ F V YV + ++ E AA+ V YW
Sbjct: 137 ITVRFPVV-------GAFANYGTRFLDPSISFVVSTIYVLQWFFVLPLEIIAAAMTVQYW 189
Query: 171 TTAVPKAAWITIFLGIIVVLNCTAVEFYGTSEAIFCSLKIFCILGIIIVSIVLFFGGGPN 230
+++ W+ IF +IV +N V +G +E F ++K + G II+ +VL GGGP+
Sbjct: 190 NSSIDPVIWVAIFYAVIVSINLFGVRGFGEAEFAFSTIKAITVCGFIILCVVLICGGGPD 249
Query: 231 HDRLGFRFWKDPGAWAYHLADGGAGRLSDIITGVIRAGFAFILGPELVVLTSTEAQDSRR 290
H+ +G ++W DPG LA+G G LS ++ G G E+ L S E +
Sbjct: 250 HEFIGAKYWHDPGC----LANGFPGVLSVLVVASYSLG-----GIEMTCLASGETDP--K 298
Query: 291 NIEKAARRFVWRLIFFYCVSSLCAGVIVSRNDPVLLNALSQGKPGAGSSPFVIGIQNAGI 350
+ A ++ WR++FF+ +S G +V + LL G +SPFVI I+ I
Sbjct: 299 GLPSAIKQVFWRILFFFLISLTLVGFLVPYTNQNLL-----GGSSVDNSPFVIAIKLHHI 353
Query: 351 KVLPHIINVCILSSAWSSGNSFMYATTRSLLSLSQEGYAPKIFNRVNRWGVPYTGVAFAT 410
K LP I+N IL S S GNS ++A++R+L S++ +G P F ++R G P G+ +
Sbjct: 354 KALPSIVNAVILISVLSVGNSCIFASSRTLCSMAHQGLIPWWFGYIDRAGRPLVGIMANS 413
Query: 411 AFSCLAYLNVSSSTADVFNWFSNISTISGFLGWICSGVAYLRFRKAV-FFNNLYDRLPFK 469
F LA+L S S ++VFNW I+ ++ + W+ ++++RFR A+ D L F
Sbjct: 414 LFGLLAFLVKSGSMSEVFNWLMAIAGLATCIVWLSINLSHIRFRLAMKAQGKSLDELEFV 473
Query: 470 TPFQPY-------------FTWFYXXXXXXXXXXNGYESFVHWNYKDFIAAYITLPLFLI 516
+ + FY +G E + +++++ A I L +F++
Sbjct: 474 SAVGIWGSAYSALINCLILIAQFYCSLWPIGGWTSGKERAKIF-FQNYLCALIMLFIFIV 532
Query: 517 LWLGHKAYTRTWSQWMI-SVSEIDVTTGLREIEEE 550
+ +K T W W + ++ +ID+ T ++I+ E
Sbjct: 533 HKIYYKCQTGKW--WGVKALKDIDLETDRKDIDIE 565
>YLL061w [E] KOG1286 Amino acid transporters
Length = 583
Score = 242 bits (617), Expect = 1e-63
Identities = 164/533 (30%), Positives = 263/533 (48%), Gaps = 37/533 (6%)
Query: 19 QTGQVYELDLTSYSNDSEKNGSLPNKPQSGDHNLKKGLKSAHIQLIAIGGCIGTGLFVGT 78
Q G +Y + S + + L N+P KK L H+ +IAIGG +GTGLF+G
Sbjct: 46 QEGLLY----SELSEEEKIQWDLANQPY------KKVLDQRHLTMIAIGGTLGTGLFIGL 95
Query: 79 SSTLYKCGPAGLFISYCIMSTIIYPVMNALAEMVCFLPGLPDENETGGSISTLCTRYVDS 138
+L GPA L I + ++ + V+ AE+ C P GS + +R++D
Sbjct: 96 GESLAS-GPASLLIGFLLVGASMLCVVQCGAELSCQYP-------VSGSYALHASRFIDP 147
Query: 139 SLGFAVGWNYVYCYVILVAAECTAASGVVTYWTTAVPKAAWITIFLGIIVVLNCTAVEFY 198
S+GF++G NY+ ++I +E S ++YW +V AAW+ I + ++LN +
Sbjct: 148 SVGFSIGINYLLMWLISYPSELVGCSLTISYWAPSVNPAAWVAIAFVLSMLLNLFGARGF 207
Query: 199 GTSEAIFCSLKIFCILGIIIVSIVLFFGGGPNH-DRLGFRFWKDPGAWAYHLADGGAGRL 257
SE KI + II+ IVL GGGP+ +G ++W DPG++A +
Sbjct: 208 AESEFYMSIFKIVALFIFIIIGIVLIAGGGPDSTGYIGTKYWHDPGSFAVPV-------F 260
Query: 258 SDIITGVIRAGFAFILGPELVVLTSTEAQDSRRNIEKAARRFVWRLIFFYCVSSLCAGVI 317
++ + A ++F G E+VVLTSTEA+ S ++ +AA+ WR+I FY V+ + G +
Sbjct: 261 KNLCNTFVSAAYSF-SGTEMVVLTSTEAR-SVSSVSRAAKGTFWRIIIFYIVTVIIIGCL 318
Query: 318 VSRNDPVLLNALSQGKPGAGSSPFVIGIQNAGI--KVLPHIINVCILSSAWSSGNSFMYA 375
V NDP L++ S +SPFVI + N G + H +N IL + +S NS +YA
Sbjct: 319 VPYNDPRLISGSS--SEDITASPFVIALSNTGAMGTRVSHFMNAVILIAVFSVCNSCVYA 376
Query: 376 TTRSLLSLSQEGYAPKIFNRVNRWGVPYTGVAFATAFSCLAYLNVSSSTADVFNWFSNIS 435
++R + L+ G PKI ++R G P G+A AF L +L VS + VF W +
Sbjct: 377 SSRLIQGLATAGQLPKICAYMDRNGRPLVGMAICGAFGLLGFLVVSKNQGTVFTWLFALC 436
Query: 436 TISGFLGWICSGVAYLRFRKAV-FFNNLYDRLPFKTPFQPYFTWFYXXXXXXXXXXNGYE 494
+IS F W C +RFR A+ D + +++ Y F Y
Sbjct: 437 SISFFTTWFCICFCQVRFRMAMKAQGRSKDDIIYRSTLGIYGGIFGCILNVLLVIGEIYV 496
Query: 495 SFV----HWNYKDFIAAYITLPLFLILWLGHKAYTRTWSQWMISVSEIDVTTG 543
S + +F +++P+ + +++GH+ Y R W W I +ID+ +G
Sbjct: 497 SAAPVGSPSSAANFFEYCMSIPIMIAVYIGHRIYRRDWRHWYIKRMDIDLDSG 549
>SPBC359.03c [E] KOG1286 Amino acid transporters
Length = 579
Score = 238 bits (607), Expect = 2e-62
Identities = 165/520 (31%), Positives = 257/520 (48%), Gaps = 39/520 (7%)
Query: 47 SGDHNLKKGLKSAHIQLIAIGGCIGTGLFVGTSSTLYKCGPAGLFISYCIMSTIIYPVMN 106
+G LK+GL + H+QL++IGG IG+GL+VG+ S L GPA + I+Y ++ +++ V+
Sbjct: 68 NGGPALKRGLSTRHMQLMSIGGAIGSGLYVGSGSALADGGPASVIINYILIGIMMFFVIY 127
Query: 107 ALAEMVCFLPGLPDENETGGSISTLCTRYVDSSLGFAVGWNYVYCYVILVAAECTAASGV 166
AL EM P GS +T TR++D + GFAV WNY + Y + E T +
Sbjct: 128 ALGEMAVAYP-------VAGSFNTYATRFIDPAWGFAVSWNYFFNYFVTFPFELTTCAIT 180
Query: 167 VTYWTTAVPKAAWITIFLGIIVVLNCTAVEFYGTSEAIFCSLKIFCILGIIIVSIVLFFG 226
T+WT V A WI+IFL +++ +N V +G E + +K+ +G II++I++ G
Sbjct: 181 FTFWTD-VNCAVWISIFLVVVIGINLFGVRVFGEVEFVLALIKVVATVGFIILAIIINCG 239
Query: 227 GGPNHDR--LGFRFWKDPGAWAYHLADGGAGRLSDIITGVIRAGFAFILGPELVVLTSTE 284
G P R +G K G G S T A F+F G E+V L + E
Sbjct: 240 GVPTDHRGYIGGSIIKQK-----PFRHGFKGFCSVYTT----AAFSF-SGTEIVGLAAAE 289
Query: 285 AQDSRRNIEKAARRFVWRLIFFYCVSSLCAGVIVSRNDPVLLNALSQGKPGAGSSPFVIG 344
D R+ + A ++ WR+ FY VS + G+++S +DP L+ G A SPFV+
Sbjct: 290 VGDPRKTLPGAVKQVFWRVAIFYIVSLILIGLLISPDDPKLM-----GNGSASVSPFVLA 344
Query: 345 IQNAGIKVLPHIINVCILSSAWSSGNSFMYATTRSLLSLSQEGYAPKIFNRVNRWGVPYT 404
IQ A IK LP + N I+ S S NS Y R+L ++ AP F +R G P
Sbjct: 345 IQEANIKGLPSVFNAVIIISVISVTNSSTYTAGRTLHGMANLKQAPAFFKYTDRLGRPLI 404
Query: 405 GVAFATAFSCLAYLNVSSSTAD-----VFNWFSNISTISGFLGWICSGVAYLRFRKAV-F 458
+ +F AY+N +++ + VF+W IS +S F W ++++ FR A
Sbjct: 405 AMIVVLSFGFFAYINEANNNGNDISDTVFDWLLAISGLSNFFTWGSICLSHIMFRLAFKK 464
Query: 459 FNNLYDRLPFKTPFQPYFTWFYXXXXXXXXXXNGYESFV----HWNYKDFIAAYITLPLF 514
+ L F +P + + Y S N DF Y+ +
Sbjct: 465 QGHSLKELGFVSPMGIWGSVIGLGFNILCLMAEFYVSLFPIGGSPNANDFFQGYLAACIT 524
Query: 515 LILWLGHKAYTRTWSQWMISVSEIDVTTGLREIE-EETKE 553
L+ ++G+K Y R+ + S+ ++D+TTGL+ E EETK+
Sbjct: 525 LVFFIGYKIYDRS---HIPSLDKLDITTGLKTYEYEETKD 561
>SPCPB1C11.02 [E] KOG1286 Amino acid transporters
Length = 505
Score = 236 bits (602), Expect = 7e-62
Identities = 162/518 (31%), Positives = 251/518 (48%), Gaps = 48/518 (9%)
Query: 51 NLKKGLKSAHIQLIAIGGCIGTGLFVGTSSTLYKCGPAGLFISYCIMSTIIYPVMNALAE 110
+L + L ++ IQ++A GG IGTGLF+G S+L + GPA L IS+ ++ +Y M AL E
Sbjct: 13 SLHRSLSASQIQMLAFGGIIGTGLFLGIGSSLAESGPASLLISFSVLGVSVYCTMLALGE 72
Query: 111 MVCFLPGLPDENETGGSISTLCTRYVDSSLGFAVGWNYVYCYVILVAAECTAASGVVTYW 170
M ++P GS T RYVD +L F++ WNY I +A+ A VV +W
Sbjct: 73 MSVYMP-------VAGSFCTYVGRYVDEALSFSLTWNYWLNDTIALASHVLATRLVVDFW 125
Query: 171 ---TTAVPKAAWITI--------------FLGIIVVLNCTAVEFYGTSEAIFCSLKIFCI 213
T P +A +++ L ++LN V +G E S+K+F +
Sbjct: 126 LIPTEGDPVSASLSLPPWKEAVRIITPITSLSANIILNMLPVGGFGEIEYWLSSIKVFTV 185
Query: 214 LGIIIVSIVLFFGGGPNHDRLGFRFWKDPGAWAYHLADGGAGRLSDIITGVIRAGFAFIL 273
I+ I+ G +GFR+WKDPGA+ + +I+ + A FA+
Sbjct: 186 AAFIVNGILCNLGVNNEKKFIGFRYWKDPGAFN--------NGIIGVISSFVNAAFAYA- 236
Query: 274 GPELVVLTSTEAQDSRRNIEKAARRFVWRLIFFYCVSSLCAGVIVSRNDPVLLNALSQGK 333
G E + LT+ EA+ + KA R R++ Y +S L G+ + N P L
Sbjct: 237 GTESIALTAGEAKSPITTLPKAIRFTAHRVLLLYIISVLVVGINLPYNTPGL------DG 290
Query: 334 PGAGSSPFVIGIQNAGIKVLPHIINVCILSSAWSSGNSFMYATTRSLLSLSQEGYAPKIF 393
SPF + G+ I+N+ ILSSA S+GN +YA TR L SL++ G+APK+F
Sbjct: 291 DSVRMSPFTFVFKKFGVPGAASIMNLVILSSALSAGNHSLYAGTRLLYSLAKSGHAPKVF 350
Query: 394 NRVNRWGVPYTGV--AFATAFSCLAYLNVSSSTADVFNWFSNISTISGFLGWICSGVAYL 451
++ N+ G+P+ V ATA CL +SS + + N+ +S + WI V+ L
Sbjct: 351 SKCNKHGIPWLSVLATSATAILCL----MSSQAGKTWGFLLNVIAVSNQISWIFIAVSSL 406
Query: 452 RFRKAVFFNNLYDRLPFKTPFQPYFTWFYXXXXXXXXXXNGYESFVHWNYKDFIAAYITL 511
RFRKA+ RL F P + GY+S + F++ Y+ +
Sbjct: 407 RFRKALRVQGKTHRLYFPNWTYPVGPYIIILLNGVFLFLQGYKSLYPFRLSLFVSYYMEI 466
Query: 512 PLFLILWLGHKAYTRTWSQWMISVSEIDVTTGLREIEE 549
P+ L L+L K Y +T ++S SE D+ T + +E+
Sbjct: 467 PIVLGLYLIWKIYKKT---KLVSSSEADLETDWKSLED 501
>YBR069c [E] KOG1286 Amino acid transporters
Length = 619
Score = 230 bits (586), Expect = 5e-60
Identities = 146/512 (28%), Positives = 256/512 (49%), Gaps = 29/512 (5%)
Query: 36 EKNGSLPNKPQSGDHNLKKGLKSAHIQLIAIGGCIGTGLFVGTSSTLYKCGPAGLFISYC 95
++N L ++ ++ NL K +KS H+ +I++G IGTGL VG L GPAGL + Y
Sbjct: 77 DRNSELESQEKN---NLTKSIKSRHLVMISLGTGIGTGLLVGNGQVLGTAGPAGLVLGYG 133
Query: 96 IMSTIIYPVMNALAEMVCFLPGLPDENETGGSISTLCTRYVDSSLGFAVGWNYVYCYVIL 155
I S ++Y ++ A E+ GL G+ + + VD SLGFAV Y ++ +
Sbjct: 134 IASIMLYCIIQAAGELGLCYAGLT------GNYTRYPSILVDPSLGFAVSVVYTIQWLTV 187
Query: 156 VAAECTAASGVVTYWTTAVPKAAWITIFLGIIVVLNCTAVEFYGTSEAIFCSLKIFCILG 215
+ + A+ V YWT+ V ++ + ++++N Y +E IF S KI ++G
Sbjct: 188 LPLQLVTAAMTVKYWTS-VNADIFVAVVFVFVIIINLFGSRGYAEAEFIFNSCKILMVIG 246
Query: 216 IIIVSIVLFFGGGPNHDRLGFRFWKDPGAWAYHLADGGAGRLSDIITGVIRAGFAFILGP 275
+I++I++ GG + +G +W +PG +A+ + T A F++ G
Sbjct: 247 FVILAIIINCGGAGDRRYIGAEYWHNPGPFAHGF--------KGVCTVFCYAAFSYG-GI 297
Query: 276 ELVVLTSTEAQDSRRNIEKAARRFVWRLIFFYCVSSLCAGVIVSRNDPVLLNALSQGKPG 335
E+++L++ E ++ ++I A ++ V+R++ Y ++++ +V N LL S G
Sbjct: 298 EVLLLSAAEQENPTKSIPNACKKVVYRILLIYMLTTILVCFLVPYNSDELLG--SSDSSG 355
Query: 336 AGSSPFVIGIQNAGIKVLPHIINVCILSSAWSSGNSFMYATTRSLLSLSQEGYAPKIFNR 395
+ +SPFVI + + G+KV+PH IN IL S S NS +Y+ R LLSL+++G PK
Sbjct: 356 SHASPFVIAVASHGVKVVPHFINAVILISVISVANSSLYSGPRLLLSLAEQGVLPKCLAY 415
Query: 396 VNRWGVPYTGVAFATAFSCLAYLNVSSSTADVFNWFSNISTISGFLGWICSGVAYLRFRK 455
V+R G P + F C+ ++ S + VF W IS++S W+ ++++RFR
Sbjct: 416 VDRNGRPLLCFFVSLVFGCIGFVATSDAEEQVFTWLLAISSLSQLFIWMSMSLSHIRFRD 475
Query: 456 AVF-FNNLYDRLPFKTPFQPYFTWFYXXXXXXXXXXNGYESFV------HWNYKDFIAAY 508
A+ + + +K + +W + + N K F Y
Sbjct: 476 AMAKQGRSMNEVGYKAQTGYWGSWLAVLIAIFFLVCQFWVAIAPVNEHGKLNVKVFFQNY 535
Query: 509 ITLPLFLILWLGHKAYTRTWSQWMISVSEIDV 540
+ +P+ L + GHK Y ++WS W I +ID+
Sbjct: 536 LAMPIVLFAYFGHKIYFKSWSFW-IPAEKIDL 566
>YBR068c [E] KOG1286 Amino acid transporters
Length = 609
Score = 229 bits (584), Expect = 9e-60
Identities = 158/526 (30%), Positives = 254/526 (48%), Gaps = 37/526 (7%)
Query: 47 SGDHNLKKGLKSAHIQLIAIGGCIGTGLFVGTSSTLYKCGPAGLFISYCIMSTIIYPVMN 106
+ D LKK +KS H+ ++++G IGTGL V + L+ GPA L I Y ++S Y ++
Sbjct: 86 TSDSKLKKSMKSRHVVMMSLGTGIGTGLLVANAKGLHYGGPAALIIGYILVSFETYFMIQ 145
Query: 107 ALAEMVCFLPGLPDENETGGSISTLCTRYVDSSLGFAVGWNYVYCYVILVAAECTAASGV 166
A EM P LP SI ++ S GFA W Y + ++ ++ E AS
Sbjct: 146 AAGEMAVTYPTLPANFNAYSSI------FISKSFGFATVWLYCFQWLTVLPLELITASMT 199
Query: 167 VTYWTTAVPKAAWITIFLGIIVVLNCTAVEFYGTSEAIFCSLKIFCILGIIIVSIVLFFG 226
+ + + +I IF +V ++ V+ YG +E IF KI I G II+SIV+ G
Sbjct: 200 IQFGNDKINPDIYILIFYVFLVFIHFFGVKAYGETEFIFNCCKILMIAGFIILSIVINCG 259
Query: 227 GGPNHDRLGFRFWKDPGAWAYHLADGGAGRLSDIITGVIRAGFAFILGPELVVLTSTEAQ 286
G N +G +W +PGA+A D GR ++ ++ A F+F G EL L+ E
Sbjct: 260 GAGNDGYIGATYWHNPGAFA---GDTSIGRFKNVCYILVTAYFSFG-GMELFALSVQEQS 315
Query: 287 DSRRNIEKAARRFVWRLIFFYCVSSLCAGVIVSRNDPVLLNALSQGKPGAGSSPFVIGIQ 346
+ R++ AA+R ++R++ Y ++ + G V ND L+ A G +SP+V+
Sbjct: 316 NPRKSTPVAAKRSIYRIVVIYLLTMILIGFNVPYNDDQLMGA---GGSATHASPYVLAAS 372
Query: 347 NAGIKVLPHIINVCILSSAWSSGNSFMYATTRSLLSLSQEGYAPKIFNRVNRWGVPYTGV 406
G+K++PHIIN IL S S NS +YA R + SL+Q+GYAPK + V+R G P +
Sbjct: 373 IHGVKIVPHIINAVILISVVSVANSSLYAGPRLICSLAQQGYAPKFLDYVDREGRPLRAL 432
Query: 407 AFATAFSCLAYLNVSSSTADVFNWFSNISTISGFLGWICSGVAYLRFRKAV-FFNNLYDR 465
F +A++ SS VF W + I+ +S W +++LRFR+A+ D
Sbjct: 433 IVCCVFGVIAFVAASSKEEIVFTWLAAIAGLSELFTWTSIMLSHLRFRQAMKVQGRSLDE 492
Query: 466 LPFKTP----------FQPYFTWFYXXXXXXXXXXNGYESFVHWNYKDFIAAYITLPLFL 515
L +K F + NG + + + F Y+ P++L
Sbjct: 493 LGYKATTGIWGSIYGVFFNILVFVAQFWVALAPLGNGGKC----DAESFFQNYLAFPIWL 548
Query: 516 ILWLGHKAYTRTWSQWMISVSEIDVTTG--------LREIEEETKE 553
+ G+ Y R ++ + + +ID+ +R+ +EE KE
Sbjct: 549 AFYFGYMVYNRDFT-LLNPLDKIDLDFHRRIYDPELMRQEDEENKE 593
>YDR046c [E] KOG1286 Amino acid transporters
Length = 604
Score = 227 bits (578), Expect = 4e-59
Identities = 150/539 (27%), Positives = 266/539 (48%), Gaps = 25/539 (4%)
Query: 44 KPQSGDHNLKKGLKSAHIQLIAIGGCIGTGLFVGTSSTLYKCGPAGLFISYCIMSTIIYP 103
K +++LKK +KS H+ ++++G IGTGL V + L GP L I Y ++S + Y
Sbjct: 78 KSMKSNNHLKKSMKSRHVVMMSLGTGIGTGLLVANAKGLSLAGPGSLVIGYVMVSFVTYF 137
Query: 104 VMNALAEMVCFLPGLPDENETGGSISTLCTRYVDSSLGFAVGWNYVYCYVILVAAECTAA 163
++ A EM P LP G+ + + ++ S GFA W + ++ ++ E +
Sbjct: 138 MVQAAGEMGVTYPTLP------GNFNAYNSIFISKSFGFATTWLFCIQWLTVLPLELITS 191
Query: 164 SGVVTYWTTAVPKAAWITIFLGIIVVLNCTAVEFYGTSEAIFCSLKIFCILGIIIVSIVL 223
S V YW + +I IF ++ ++ V+ YG +E IF S KI + G II+S+V+
Sbjct: 192 SMTVKYWNDTINADVFIVIFYVFLLFIHFFGVKAYGETEFIFNSCKILMVAGFIILSVVI 251
Query: 224 FFGGGPNHDRLGFRFWKDPGAWAYHLADGGAGRLSDIITGVIRAGFAFILGPELVVLTST 283
GG +G ++W+DPG++A GA R I ++ A F+F G EL VL+
Sbjct: 252 NCGGAGVDGYIGGKYWRDPGSFA---EGSGATRFKGICYILVSAYFSFG-GIELFVLSIN 307
Query: 284 EAQDSRRNIEKAARRFVWRLIFFYCVSSLCAGVIVSRNDPVLLNALSQGKPGAGSSPFVI 343
E + R++ AA+R V+R++ Y ++ + G V N+ L+ + G +SP+V+
Sbjct: 308 EQSNPRKSTPVAAKRSVYRILIIYLLTMILIGFNVPHNNDQLMGS---GGSATHASPYVL 364
Query: 344 GIQNAGIKVLPHIINVCILSSAWSSGNSFMYATTRSLLSLSQEGYAPKIFNRVNRWGVPY 403
++V+PHIIN IL S S NS +YA R + SL+Q+GYAPK N ++R G P
Sbjct: 365 AASIHKVRVIPHIINAVILISVISVANSALYAAPRLMCSLAQQGYAPKFLNYIDREGRPL 424
Query: 404 TGVAFATAFSCLAYLNVSSSTADVFNWFSNISTISGFLGWICSGVAYLRFRKAV-FFNNL 462
+ + + ++ S F W + I+ +S W ++++RFRKA+
Sbjct: 425 RALVVCSLVGVVGFVACSPQEEQAFTWLAAIAGLSELFTWSGIMLSHIRFRKAMKVQGRS 484
Query: 463 YDRLPFKTP---FQPYFTWFYXXXXXXXXXXNGYESFVHWNYKD---FIAAYITLPLFLI 516
D + +K + Y+ F+ + D F +Y+ PL++
Sbjct: 485 LDEVGYKANTGIWGSYYGVFFNMLVFMAQFWVALSPIGNGGKCDAQAFFESYLAAPLWIF 544
Query: 517 LWLGHKAYTRTWSQWMISVSEIDVTTGLR----EIEEETKELNARRIPPRNLWEKILEW 571
+++G+ Y R ++ ++ + +ID+ R EI + E N R+ +++ ++ ++
Sbjct: 545 MYVGYMVYKRDFT-FLNPLDKIDLDFHRRVYDPEIMRQEDEENKERLKNSSIFVRVYKF 602
>YFL055w [E] KOG1286 Amino acid transporters
Length = 558
Score = 216 bits (550), Expect = 7e-56
Identities = 144/477 (30%), Positives = 226/477 (47%), Gaps = 25/477 (5%)
Query: 45 PQSGDHNLKKGLKSAHIQLIAIGGCIGTGLFVGTSSTLYKCGPAGLFISYCIMSTIIYPV 104
PQ+G +K+ LK+ HI L+A+GG IG G VG + L K GP L + + I+ I + V
Sbjct: 45 PQTG---VKRALKNRHISLLALGGVIGPGCLVGAGNALNKGGPLALLLGFSIIGIIAFSV 101
Query: 105 MNALAEMVCFLPGLPDENETGGSISTLCTRYVDSSLGFAVGWNYVYCYVILVAAECTAAS 164
M ++ EM+ P +GG +TL R+ +L G+ YV + ++A E S
Sbjct: 102 MESIGEMITLYP-------SGGGFTTLARRFHSDALPAVCGYAYVVVFFAVLANEYNTLS 154
Query: 165 GVVTYWTTAVPKAAWITIFLGIIVVLNCTAVEFYGTSEAIFCSLKIFCILGIIIVSIVLF 224
++ +W VP +I IF + V +G +E LKI ++ I SIV
Sbjct: 155 SILQFWGPQVPLYGYILIFWFAFEIFQLVGVGLFGETEYWLAWLKIVGLVAYYIFSIVYI 214
Query: 225 FGGGPNHDRLGFRFWKDPGAWAYHLADGGAGRLSDIITGVIRAGFAFILGPELVVLTSTE 284
G N GF +W PGA L+ G G I V F G E V L +TE
Sbjct: 215 SGDIRNRPAFGFHYWNSPGA----LSHGFKG-----IAIVFVFCSTFYSGTESVALAATE 265
Query: 285 AQDSRRNIEKAARRFVWRLIFFYCVSSLCAGVIVSRNDPVLLNALSQGKPGAGSSPFVIG 344
+++ + + A R+ +WR++ Y ++ G V +DP L + K SP I
Sbjct: 266 SKNPGKAVPLAVRQTLWRILVVYIGIAVFYGATVPFDDPNLSASTKVLK-----SPIAIA 320
Query: 345 IQNAGIKVLPHIINVCILSSAWSSGNSFMYATTRSLLSLSQEGYAPKIFNRVNRWGVPYT 404
I AG H++N IL + S+ N +Y +R+L L+ EG APKI +R GVP
Sbjct: 321 ISRAGWAGGAHLVNAFILITCISAINGSLYIGSRTLTHLAHEGLAPKILAWTDRRGVPIP 380
Query: 405 GVAFATAFSCLAYLNVSSSTADVFNWFSNISTISGFLGWICSGVAYLRFRKA-VFFNNLY 463
+ A ++ +NVS A+ +++ N+S + F+ W +LR RKA V
Sbjct: 381 AITVFNALGLISLMNVSVGAANAYSYIVNLSGVGVFIVWGVISYTHLRIRKAWVAQGRSI 440
Query: 464 DRLPFKTPFQPYFTWFYXXXXXXXXXXNGYESFVHWNYKDFIAAYITLPLFLILWLG 520
+ LP++ F P+ G+ FV ++ +F+ AYI LP+ ++L++G
Sbjct: 441 EELPYEALFYPWTPVLSLAANIFLALIQGWSYFVPFDAGNFVDAYILLPVGILLYIG 497
>SPAC1039.09 [E] KOG1286 Amino acid transporters
Length = 580
Score = 216 bits (550), Expect = 7e-56
Identities = 151/521 (28%), Positives = 252/521 (47%), Gaps = 41/521 (7%)
Query: 45 PQSGD-HNLKKGLKSAHIQLIAIGGCIGTGLFVGTSSTLYKCGPAGLFISYCIMSTIIYP 103
P+ G LK+ L + HIQ+I IGG IGTG++VG+ +TL + G A + I Y ++ +++
Sbjct: 71 PEDGKPQKLKRTLTARHIQMIGIGGAIGTGVWVGSKNTLREGGAASVLICYSLVGSMVLM 130
Query: 104 VMNALAEMVCFLPGLPDENETGGSISTLCTRYVDSSLGFAVGWNYVYCYVILVAAECTAA 163
+ +L E+ P GS T TR++ S GF +GWNY+ ++ E A
Sbjct: 131 TVYSLGELAVAFP-------INGSFHTYGTRFIHPSWGFTLGWNYLASFLATYPLELITA 183
Query: 164 SGVVTYWTTAVPKAAWITIFLGIIVVLNCTAVEFYGTSEAIFCSLKIFCILGIIIVSIVL 223
S + +W + WIT+F+ ++ +N V YG E SLK+ ++G II IV+
Sbjct: 184 SICLQFWIN-INSGIWITVFIALLCFVNMFGVRGYGEVEFFVSSLKVMAMVGFIICGIVI 242
Query: 224 FFGGGPNHDRLGFR----FWKDPGAWAYHLADGGAGRLSDIITGVIRAGFAFILGPELVV 279
GG D G+ F K+ +H G S T A F++ G E +
Sbjct: 243 DCGG-VRTDHRGYIGATIFRKNAFIHGFH------GFCSVFST----AAFSYA-GTEYIG 290
Query: 280 LTSTEAQDSRRNIEKAARRFVWRLIFFYCVSSLCAGVIVSRNDPVLLNALSQGKPGAGSS 339
+ ++E ++ + KA ++ R+ FY ++ +++S D L LS +S
Sbjct: 291 IAASETKNPAKAFPKAVKQVFIRVSLFYILALFVVSLLISGRDE-RLTTLS----ATAAS 345
Query: 340 PFVIGIQNAGIKVLPHIINVCILSSAWSSGNSFMYATTRSLLSLSQEGYAPKIFNRVNRW 399
PF++ + +A I+ LPH++N IL S ++ N Y +R+L S++++G+APK F V+R
Sbjct: 346 PFILALMDAKIRGLPHVLNAVILISVLTAANGITYTGSRTLHSMAEQGHAPKWFKYVDRE 405
Query: 400 GVPYTGVAFATAFSCLAYLNVSSSTADVFNWFSNISTISGFLGWICSGVAYLRFRKAV-F 458
G P +AF F L Y+ S+ + VF+W +IS ++ W+ V+Y+ +R A
Sbjct: 406 GRPLLAMAFVLCFGALGYICESAQSDTVFDWLLSISNLATLFVWLSINVSYIIYRLAFKK 465
Query: 459 FNNLYDRLPFKTPFQPYFTWFYXXXXXXXXXXNGYESFVHWNYKD----FIAAYITLPLF 514
YD + + +PF Y + Y S F +Y+ P+
Sbjct: 466 QGKSYDEVGYHSPFGIYGACYGAFIIILVFITEFYVSIFPIGASPDAGAFFQSYLCFPVV 525
Query: 515 LILWLGHKAYTRTWSQWMISVSEIDVTTGLRE---IEEETK 552
+I+++ H TR Q +SEID+ TG + +EE K
Sbjct: 526 VIVFIAHALITR---QKFRKLSEIDLDTGFSKYDRLEESDK 563
>YDR160w [E] KOG1286 Amino acid transporters
Length = 852
Score = 188 bits (477), Expect = 2e-47
Identities = 146/589 (24%), Positives = 270/589 (45%), Gaps = 78/589 (13%)
Query: 50 HNLKKGLKSAHIQLIAIGGCIGTGLFVGTSSTLYKCGPAGLFISYCIMSTIIYPVMNALA 109
+++++ LK HIQ+++IG C GLF+ + GP G + + + +II M +
Sbjct: 275 YHIQRKLKVRHIQMLSIGACFSVGLFLTSGKAFSIAGPFGTLLGFGLTGSIILATMLSFT 334
Query: 110 EMVCFLPGLPDENETGGSISTLCTRYVDSSLGFAVGWNYVYCYVILVAAECTAASGVVTY 169
E+ +P S L +R+V+ + GFA+GW Y ++ + A+ ++++ ++Y
Sbjct: 335 ELSTLIP-------VSSGFSGLASRFVEDAFGFALGWTYWISCMLALPAQVSSSTFYLSY 387
Query: 170 WTTA-VPK---AAWITIFLGIIVVLNCTAVEFYGTSEAIFCSLKIFCILGIIIVSIVLFF 225
+ + K A +IT+F +V+N V G + K+ + ++ I+L
Sbjct: 388 YNNVNISKGVTAGFITLFSAFSIVVNLLDVSIMGEIVYVAGISKVIIAILMVFTMIILNA 447
Query: 226 GGGPN-HDRLGFRFWKDPGAW----------AYHLADGGAGRLSDI----------ITGV 264
G G + H+ +GFR+W + + LAD G G I + +
Sbjct: 448 GHGNDIHEGVGFRYWDSSKSVRNLTYGLYRPTFDLADAGEGSKKGISGPKGRFLATASVM 507
Query: 265 IRAGFAFILGPELVVLTSTEAQDSRRNIEKAARRFVWRLIFFYCVSSLCAGVIVSRNDPV 324
+ + FAF G E+ L S EA + R+ I A +R ++ Y G+ + DP
Sbjct: 508 LISTFAFS-GVEMTFLASGEAINPRKTIPSATKRTFSIVLISYVFLIFSVGINIYSGDPR 566
Query: 325 LLN-----------ALSQG--------------------KPGAG-SSPFVIGIQNAGIKV 352
LL+ A+ +G G G SSP+V+ +QN G+
Sbjct: 567 LLSYFPGISEKRYEAIIKGTGMDWRLRTNCRGGIDYRQISVGTGYSSPWVVALQNFGLCT 626
Query: 353 LPHIINVCILSSAWSSGNSFMYATTRSLLSLSQEGYAPKIFNRVNRWGVPYTGVAFATAF 412
N ++ ++G S +++ +R+L ++S + AP +F ++ GVPY V F++ F
Sbjct: 627 FASAFNAILIFFTATAGISSLFSCSRTLYAMSVQRKAPPVFEICSKRGVPYVSVIFSSLF 686
Query: 413 SCLAYLNVSSSTADVFNWFSNISTISGFLGWICSGVAYLRF------RKAVFFNNLYDRL 466
S +AY+ V + + F+ +N+S+ S + W+ +++LRF RK + N
Sbjct: 687 SVIAYIAVDQTAIENFDVLANVSSASTSIIWMGLNLSFLRFYYALKQRKDIISRN-DSSY 745
Query: 467 PFKTPFQPYFTWFYXXXXXXXXXXNGYESFVH--WNYKDFIAAYITLPLFLILWLGHKAY 524
P+K+PFQPY + GY +F+H W+ K F +AY L F I + +K
Sbjct: 746 PYKSPFQPYLAIYGLVGCSLFVIFMGYPNFIHHFWSTKAFFSAYGGLMFFFISYTAYKVL 805
Query: 525 TRTWSQWMISVSEIDVTTGLREIEEETKELNARRIPP-RNLWEKILEWL 572
+ Q + ++D+ +G RE++ +++ + R +K++ WL
Sbjct: 806 GTSKIQ---RLDQLDMDSGRREMDRTDWTEHSQYLGTYRERAKKLVTWL 851
>SPAC869.11 [E] KOG1286 Amino acid transporters
Length = 423
Score = 167 bits (422), Expect = 5e-41
Identities = 126/440 (28%), Positives = 199/440 (44%), Gaps = 37/440 (8%)
Query: 144 VGWNYVYCYVILVAAECTAASGVVTYWTTAVPKAAWITIFLGIIVVLNCTAVEFYGTSEA 203
V WNY Y + E T + YWT + AAWI+IFL +I+++N V YG E
Sbjct: 1 VSWNYFINYFVTFPLELTTCAITFRYWTD-INSAAWISIFLVVIIIVNLFGVRAYGEVEF 59
Query: 204 IFCSLKIFCILGIIIVSIVLFFGGGPNHDRLGFRFWKDPGAWAYH--LADGGAGRLSDII 261
I ++K+ G II++I++ GG P D G+ G+ H G G S
Sbjct: 60 ILSTVKVVATFGFIILAIIINCGGVPT-DHRGYI----GGSIIKHKPFRHGFKGFCSVFT 114
Query: 262 TGVIRAGFAFILGPELVVLTSTEAQDSRRNIEKAARRFVWRLIFFYCVSSLCAGVIVSRN 321
T A F+F G E++ L + E + ++ + A ++ WR+ FY VS + G+++S +
Sbjct: 115 T----AAFSFS-GTEVIGLAAAEVDNPQKALPHAVKQVFWRIAIFYVVSLILIGLLISPD 169
Query: 322 DPVLLNALSQGKPGAGSSPFVIGIQNAGIKVLPHIINVCILSSAWSSGNSFMYATTRSLL 381
DP L+ G SPFV+ I+ A IK LP + N I+ S S NS Y R+L
Sbjct: 170 DPNLM-----GNGSTSVSPFVLAIKEANIKGLPSVFNAVIIISVVSVTNSSTYTAGRTLH 224
Query: 382 SLSQEGYAPKIFNRVNRWGVPYTGVAFATAFSCLAYLNVSSSTAD-----VFNWFSNIST 436
++ AP F +R G P + F AY+N + + VFNW +S
Sbjct: 225 GMANLKQAPSFFKYTDRLGRPLLAMIVVLLFGFFAYINEADKNGNDVSDTVFNWLLALSG 284
Query: 437 ISGFLGW----ICSGVAYLRFRKAVFFNNLYDRLPFKTPFQPYFTWFYXXXXXXXXXXNG 492
+S F W +C + L F+K + L F +P + +
Sbjct: 285 LSNFFTWGSICLCHIIFRLAFKKQ---GHSLKELGFVSPMGIWGSCIGLFFNILCLMAQF 341
Query: 493 YESFV----HWNYKDFIAAYITLPLFLILWLGHKAYTRTWSQWMISVSEIDVTTGLREIE 548
Y S N DF Y+ P+ L ++G+K Y R+ + S+ ++D+TTGL+ E
Sbjct: 342 YVSLFPIGGKPNANDFFQGYLAAPVTLAFFIGYKIYDRS---HIPSLDKLDITTGLKTYE 398
Query: 549 EETKELNARRIPPRNLWEKI 568
+E + + +++KI
Sbjct: 399 NLDEEEDEPTTASKRIFKKI 418
>SPBC359.01 [E] KOG1286 Amino acid transporters
Length = 187
Score = 88.2 bits (217), Expect = 3e-17
Identities = 44/120 (36%), Positives = 67/120 (55%), Gaps = 7/120 (5%)
Query: 52 LKKGLKSAHIQLIAIGGCIGTGLFVGTSSTLYKCGPAGLFISYCIMSTIIYPVMNALAEM 111
LK+ L S H+Q+I++GG IG+GL+VG+ S GPA + I+Y ++ ++ V+ AL E+
Sbjct: 73 LKRKLTSRHMQMISVGGAIGSGLYVGSGSAFADGGPASVIINYILIGIMMIFVIYALGEL 132
Query: 112 VCFLPGLPDENETGGSISTLCTRYVDSSLGFAVGWNYVYCYVILVAAECTAASGVVTYWT 171
P GS +T TR++D + GFAV WNY Y + E T + +WT
Sbjct: 133 AIAYP-------VAGSFNTYATRFIDPAWGFAVSWNYFLNYFVTCPLELTTCAITFKFWT 185
>Hs6912670 [E] KOG1287 Amino acid transporters
Length = 535
Score = 54.7 bits (130), Expect = 4e-07
Identities = 91/447 (20%), Positives = 181/447 (40%), Gaps = 62/447 (13%)
Query: 31 YSNDSEKN----GSLPNKPQSGDHN----LKKGLKSAHIQLIAIGGCIGTGLFVGTSSTL 82
+ N++EK G P++G LKK + I +G IG+G+FV L
Sbjct: 7 HRNNTEKKHPGGGESDASPEAGSGGGGVALKKEIGLVSACGIIVGNIIGSGIFVSPKGVL 66
Query: 83 YKCGPAGLFISYCIMSTIIYPVMNAL--AEMVCFLPGLPDENETGGSISTLCTRYVDSSL 140
G GL + I++ I V+ AL AE+ +P ++GG S YV
Sbjct: 67 ENAGSVGLALIVWIVTGFI-TVVGALCYAELGVTIP------KSGGDYS-----YVKDIF 114
Query: 141 GFAVGWNYVYCYVILVAAECTAASGVV-------TYWTTAVPKAAWITIFLGIIVVL--- 190
G G+ ++ V+++ A + + T P + + + I ++L
Sbjct: 115 GGLAGFLRLWIAVLVIYPTNQAVIALTFSNYVLQPLFPTCFPPESGLRLLAAICLLLLTW 174
Query: 191 -NCTAVEFYGTSEAIFCSLKIFCILGIIIVSIVLFFGGGPNHDRLGFRFWKDPGAWAYHL 249
NC++V + + IF + K+ + III+ IV G FW +P
Sbjct: 175 VNCSSVRWATRVQDIFTAGKLLALALIIIMGIVQICKGE--------YFWLEPKNAFEDF 226
Query: 250 ADGGAGRLSDIITGVIRAGFAFILGPELVVLTSTEAQDSRRNIEKAARRFVWRLIFFYCV 309
+ G + ++ FA+ G + + E D +N+ +A + + F Y
Sbjct: 227 QEPDIGL---VALAFLQGSFAY-GGWNFLNYVTEELVDPYKNLPRAIFISIPLVTFVYVF 282
Query: 310 SSLCAGVIVSRNDPVLLNALSQGKPGAGSSPFVIGIQNAGIKVLPHIINVCILSSAWSSG 369
+++ +S + + NA++ + + V+ I+ + + S +
Sbjct: 283 ANVAYVTAMSPQELLASNAVA------------VTFGEKLLGVMAWIMPISVALSTFGGV 330
Query: 370 NSFMYATTRSLLSLSQEGYAPKIFNRVNRWGVPYTGVAFATAFSCLAYLNVSSSTADVFN 429
N ++ ++R + ++EG+ P + ++ V A F+C++ L + T+D++
Sbjct: 331 NGSLFTSSRLFFAGAREGHLPSVLAMIH---VKRCTPIPALLFTCISTL-LMLVTSDMYT 386
Query: 430 WFSNISTISG-FLGWICSGVAYLRFRK 455
+ + I+ F G +G LR++K
Sbjct: 387 LINYVGFINYLFYGGTVAGQIVLRWKK 413
>7293641 [E] KOG1286 Amino acid transporters
Length = 804
Score = 51.6 bits (122), Expect = 3e-06
Identities = 64/287 (22%), Positives = 111/287 (38%), Gaps = 34/287 (11%)
Query: 42 PNKPQSGDHNLKKGLKSAHIQLIAIGGCIGTGLFVGTSSTLYKCGPAGLFISYCIMSTII 101
P KP+ L K L + + + IG C GTG+++ K G+ IS+ I +
Sbjct: 40 PQKPK-----LTKCLNTLDLTSLGIGSCCGTGMYLVAGMVAQKIAGPGVIISFIIAAIAS 94
Query: 102 YPVMNALAEMVCFLPGLPDENETGGSISTLCTRYVDSSLGFAVGWNYVYCYVI-LVAAEC 160
AE +P T GS V + F +GWN + Y+I A C
Sbjct: 95 IFSGACYAEFGVRVP------HTSGSAYMYSYVAVGEFVAFIIGWNMILEYLIGTSACAC 148
Query: 161 TAASGVVTYWTTAVPKAAWITI---------FLGIIVVLNCTAVEFYGTSEAIFCSLKIF 211
+S + A+ + +I F+ + L T V G S+++ +
Sbjct: 149 ALSSSFDSLTGNAIARTISESIGTIFGKPPDFIAFGITLLMTCVLAMGASKSVIFN---H 205
Query: 212 CILGIIIVSIVLFFGGGPNHDRLGFRFWKDPGAWAYHLADGGAGRLSDIITGVIRAGFAF 271
+ + + + V G F+ D W+ H G S + +G +AF
Sbjct: 206 SLNAVNLATWVFVMAAG--------LFYVDTKTWSEHQGFLPYG-WSGVFSGAATCFYAF 256
Query: 272 ILGPELVVLTSTEAQDSRRNIEKAARRFVWRLIFFYCVSSLCAGVIV 318
I G +++ T EA + +++I KA + ++ Y SL ++V
Sbjct: 257 I-GFDIIATTGEEAHNPQKSIPKAIVGSLVVVLIAYVSVSLVLTLVV 302
>Hs14777542 [E] KOG1286 Amino acid transporters
Length = 635
Score = 50.4 bits (119), Expect = 7e-06
Identities = 94/438 (21%), Positives = 178/438 (40%), Gaps = 66/438 (15%)
Query: 42 PNKPQSGDHNLKKGLKSAHIQLIAIGGCIGTGLFVGTSSTLYKCGPAGLFISYCIMSTII 101
P + + + +L++ L + + L+ +GG +G+GL+V T + + + +S+ + +
Sbjct: 23 PLEDSTMETSLRRCLSTLDLTLLGVGGMVGSGLYVLTGAVAKEVAGPAVLLSFGVAAVAS 82
Query: 102 YPVMNALAEMVCFLPGLPDENETGGSISTLCTRYVDSS--LGFAVGWNYVYCYVILVAAE 159
AE +P TG S YV F +GWN + Y+I AA
Sbjct: 83 LLAALCYAEFGARVP------RTG---SAYLFTYVSMGELWAFLIGWNVLLEYIIGGAAV 133
Query: 160 CTAASGVVT--------------YWTTAVPKAAWITIFLGIIVVLNCTAVEFYGTSEAIF 205
A SG + + VP FL ++L +A G + +
Sbjct: 134 ARAWSGYLDSMFSHSIRNFTETHVGSWQVPLLGHYPDFLAAGIILLASAFVSCGARVSSW 193
Query: 206 CSLKIFCILGIIIVSIVLFFGGGPNHDRLGFRFWKDPGAWAYHLADGGAGRLSDIITGVI 265
+ I ++I+ IV+ LGF P W+ S ++ G
Sbjct: 194 LNHTFSAISLLVILFIVI----------LGF-ILAQPHNWSADEGGFAPFGFSGVMAGTA 242
Query: 266 RAGFAFILGPELVVLTSTEAQDSRRNIEKAARRFVWRLIFFYCVSSLCAGVIVSRN---- 321
+AF+ G +++ +S EAQ+ RR++ A + Y + S ++V +
Sbjct: 243 SCFYAFV-GFDVIAASSEEAQNPRRSVPLAIAISLAIAAGAYILVSTVLTLMVPWHSLDP 301
Query: 322 DPVLLNALSQ-GKPGAGSSPFVIGIQNAGIKVLPHIINVCILSSAWSSGNSFMYATTRSL 380
D L +A Q G AG F++ AG ++C +++ S +++ R +
Sbjct: 302 DSALADAFYQRGYRWAG---FIVA---AG--------SICAMNTVLL---SLLFSLPRIV 344
Query: 381 LSLSQEGYAPKIFNRVN-RWGVPYTG-VAFATAFSCLAYLNVSSSTADVFNWFSNISTIS 438
+++ +G ++F V+ R VP G +AF + LA L S F ++ T+
Sbjct: 345 YAMAADGLFFQVFAHVHPRTQVPVAGTLAFGLLTAFLALLLDLESLVQ----FLSLGTLL 400
Query: 439 GFLGWICSGVAYLRFRKA 456
+ ++ + + LRF+K+
Sbjct: 401 AYT-FVATSIIVLRFQKS 417
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.324 0.140 0.446
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,113,009
Number of Sequences: 60738
Number of extensions: 1494480
Number of successful extensions: 4466
Number of sequences better than 1.0e-05: 33
Number of HSP's better than 0.0 without gapping: 30
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 4294
Number of HSP's gapped (non-prelim): 44
length of query: 573
length of database: 30,389,216
effective HSP length: 112
effective length of query: 461
effective length of database: 23,586,560
effective search space: 10873404160
effective search space used: 10873404160
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)