ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI6310 check: MH T KOG0032 Signal transduction mechanisms Ca2+/calmodulin-dependent protein kinase, EF-Hand protein superfamily
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI6310 2200066 2198606 -487
(487 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YOR351c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 465 e-131
SPAC14C4.03 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 216 8e-56
Hs6005850 [D] KOG0615 Serine/threonine protein kinase Chk2 and r... 162 1e-39
7298652 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 152 1e-36
Hs4502553 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 150 3e-36
Hs14196445 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 150 3e-36
CE28061 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 148 2e-35
CE28060 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 148 2e-35
CE28059 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 148 2e-35
CE28058 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 148 2e-35
CE28057 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 148 2e-35
CE28056 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 148 2e-35
CE28055 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 148 2e-35
CE28054 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 148 2e-35
CE28053 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 148 2e-35
CE28051 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 148 2e-35
CE25046 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 142 9e-34
Hs14141724 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase ... 142 1e-33
CE28251 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 142 1e-33
7304358 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 142 1e-33
YPL153c [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 141 3e-33
SPCC18B5.11c [D] KOG0615 Serine/threonine protein kinase Chk2 an... 140 3e-33
SPACUNK12.02c [T] KOG0032 Ca2+/calmodulin-dependent protein kina... 140 6e-33
Hs7706286 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase E... 139 7e-33
Hs22043888 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 139 1e-32
Hs4758128_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 137 5e-32
Hs14776113 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 136 6e-32
7304311 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 136 6e-32
CE27297 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 135 1e-31
Hs9966875 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 135 2e-31
Hs20127418 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase ... 134 4e-31
Hs14916455 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 132 1e-30
Hs4502557 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 132 2e-30
CE09360 [Z] KOG0613 Projectin/twitchin and related proteins 131 3e-30
Hs20479818 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 130 3e-30
YOL016c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 130 6e-30
At1g12580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 129 8e-30
YDL101c [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 129 1e-29
Hs14728804 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 128 2e-29
At2g17890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 127 5e-29
Hs16950621 [Z] KOG0613 Projectin/twitchin and related proteins 125 1e-28
Hs16950613 [Z] KOG0613 Projectin/twitchin and related proteins 125 1e-28
Hs16950611 [Z] KOG0613 Projectin/twitchin and related proteins 125 1e-28
Hs16950601 [Z] KOG0613 Projectin/twitchin and related proteins 125 1e-28
Hs14670383 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 125 1e-28
YFR014c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 125 1e-28
CE02377 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 125 1e-28
At5g24430 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 124 3e-28
At2g46700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 124 3e-28
At5g66210 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 123 7e-28
Hs4759050 [T] KOG0603 Ribosomal protein S6 kinase 122 9e-28
At4g09570 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 122 9e-28
At1g35670 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 122 1e-27
Hs7657526 [T] KOG0603 Ribosomal protein S6 kinase 122 2e-27
HsM4505191 [T] KOG0607 MAP kinase-interacting kinase and related... 121 2e-27
Hs20149547 [T] KOG0603 Ribosomal protein S6 kinase 121 2e-27
At3g49370 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 121 2e-27
CE18967 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD a... 121 3e-27
CE27583 [T] KOG0604 MAP kinase-activated protein kinase 2 120 5e-27
CE17545 [T] KOG0604 MAP kinase-activated protein kinase 2 120 5e-27
CE18169 [T] KOG0603 Ribosomal protein S6 kinase 120 6e-27
CE13014 [T] KOG0603 Ribosomal protein S6 kinase 120 6e-27
At1g49580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 120 6e-27
7295638 [T] KOG0603 Ribosomal protein S6 kinase 120 6e-27
Hs19923468 [T] KOG4236 Serine/threonine protein kinase PKC mu/PK... 119 8e-27
CE12518 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 119 1e-26
Hs4502567_1 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase... 119 1e-26
Hs19923570 [T] KOG0603 Ribosomal protein S6 kinase 119 1e-26
Hs14993776 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 119 1e-26
At4g30960 [T] KOG0583 Serine/threonine protein kinase 119 1e-26
At3g50530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 119 1e-26
7292679 [G] KOG0599 Phosphorylase kinase gamma subunit 119 1e-26
CE05507 [T] KOG0603 Ribosomal protein S6 kinase 118 2e-26
At5g23580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 118 2e-26
Hs4826684_1 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 118 2e-26
7290629 [T] KOG0604 MAP kinase-activated protein kinase 2 118 2e-26
At1g30270 [T] KOG0583 Serine/threonine protein kinase 117 4e-26
7300778 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 117 4e-26
Hs4557511 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 117 5e-26
Hs4759052 [T] KOG0603 Ribosomal protein S6 kinase 116 7e-26
Hs4506735 [T] KOG0603 Ribosomal protein S6 kinase 116 7e-26
At3g19100 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 116 7e-26
Hs5453882 [G] KOG0599 Phosphorylase kinase gamma subunit 116 9e-26
Hs4758700 [T] KOG0604 MAP kinase-activated protein kinase 2 116 9e-26
Hs4506075 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD... 116 9e-26
Hs5031689 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD... 115 1e-25
CE03584 [T] KOG0607 MAP kinase-interacting kinase and related se... 115 1e-25
CE18058_1 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 115 1e-25
At3g56760 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 114 3e-25
At3g23000 [T] KOG0583 Serine/threonine protein kinase 114 3e-25
At2g41140 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 114 3e-25
At1g76040 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 114 3e-25
At1g12680 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 114 3e-25
HsM4506035 [T] KOG0604 MAP kinase-activated protein kinase 2 114 3e-25
Hs21237768 [T] KOG0604 MAP kinase-activated protein kinase 2 114 3e-25
Hs21237765 [T] KOG0604 MAP kinase-activated protein kinase 2 114 3e-25
Hs9994197 [T] KOG0607 MAP kinase-interacting kinase and related ... 113 6e-25
Hs4758192 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 113 6e-25
Hs14589904 [T] KOG0604 MAP kinase-activated protein kinase 2 113 6e-25
Hs10863901 [T] KOG0604 MAP kinase-activated protein kinase 2 113 6e-25
7296128 [T] KOG0583 Serine/threonine protein kinase 113 6e-25
SPAC22E12.14c [RT] KOG0598 Ribosomal protein S6 kinase and relat... 113 7e-25
Hs4505785 [G] KOG0599 Phosphorylase kinase gamma subunit 113 7e-25
7299437 [R] KOG0586 Serine/threonine protein kinase 113 7e-25
At4g36070 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 112 1e-24
7303019 [Z] KOG0613 Projectin/twitchin and related proteins 112 1e-24
At2g38910 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 111 2e-24
At1g18890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 111 2e-24
CE04603 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 110 5e-24
At2g30360 [T] KOG0583 Serine/threonine protein kinase 110 5e-24
7304283 [Z] KOG0613 Projectin/twitchin and related proteins 110 5e-24
7300413 [T] KOG0583 Serine/threonine protein kinase 110 6e-24
Hs4826948 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 109 1e-23
Hs20143922 [Z] KOG0613 Projectin/twitchin and related proteins 109 1e-23
Hs20143918 [Z] KOG0613 Projectin/twitchin and related proteins 109 1e-23
Hs20143914 [Z] KOG0613 Projectin/twitchin and related proteins 109 1e-23
Hs19747267 [Z] KOG0613 Projectin/twitchin and related proteins 109 1e-23
At4g23650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 109 1e-23
At4g18700 [T] KOG0583 Serine/threonine protein kinase 109 1e-23
7294770 [T] KOG0603 Ribosomal protein S6 kinase 109 1e-23
Hs22057171 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 108 1e-23
At5g58380 [T] KOG0583 Serine/threonine protein kinase 108 1e-23
At5g45820 [T] KOG0583 Serine/threonine protein kinase 108 1e-23
At5g01810 [T] KOG0583 Serine/threonine protein kinase 108 1e-23
7299507 [T] KOG0607 MAP kinase-interacting kinase and related se... 108 1e-23
7299438 [R] KOG0586 Serine/threonine protein kinase 108 1e-23
SPBC32C12.03c [T] KOG0583 Serine/threonine protein kinase 108 2e-23
At2g41860 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 108 2e-23
At1g74740 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 108 2e-23
At1g48260 [T] KOG0583 Serine/threonine protein kinase 108 2e-23
Hs5902140_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 108 2e-23
YMR001c [D] KOG0575 Polo-like serine/threonine protein kinase 107 3e-23
Hs4506739 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 107 3e-23
Hs20545357 [T] KOG0583 Serine/threonine protein kinase 107 3e-23
CE06635 [Z] KOG0613 Projectin/twitchin and related proteins 107 3e-23
CE06634 [Z] KOG0613 Projectin/twitchin and related proteins 107 3e-23
At3g10660 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 107 3e-23
At2g31500 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 107 3e-23
Hs13129008 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 107 4e-23
ECU07g0360 [D] KOG0580 Serine/threonine protein kinase 107 4e-23
CE20167 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD a... 107 4e-23
At4g04720 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 107 4e-23
At2g35890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 107 4e-23
YHR205w [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 107 5e-23
SPCC24B10.07 [RT] KOG0598 Ribosomal protein S6 kinase and relate... 107 5e-23
At4g14580 [T] KOG0583 Serine/threonine protein kinase 107 5e-23
At3g20410 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 106 7e-23
YGL158w [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 106 9e-23
Hs4506737 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 106 9e-23
At4g04740 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 106 9e-23
Hs5032091 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 105 1e-22
Hs4506057 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 105 1e-22
CE15475 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 105 1e-22
CE15473 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 105 1e-22
At5g45810 [T] KOG0583 Serine/threonine protein kinase 105 1e-22
At5g19450 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 105 1e-22
At5g07070 [T] KOG0583 Serine/threonine protein kinase 105 1e-22
SPAC1B9.02c [RT] KOG0598 Ribosomal protein S6 kinase and related... 105 2e-22
Hs8923922 [R] KOG0586 Serine/threonine protein kinase 105 2e-22
Hs10835065 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 105 2e-22
CE27768 [R] KOG0586 Serine/threonine protein kinase 105 2e-22
CE23838 [R] KOG0586 Serine/threonine protein kinase 105 2e-22
CE21879 [D] KOG0590 Checkpoint kinase and related serine/threoni... 105 2e-22
7290249 [R] KOG0586 Serine/threonine protein kinase 105 2e-22
At1g50700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 105 2e-22
Hs13899225 [R] KOG0586 Serine/threonine protein kinase 104 3e-22
CE05780 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 104 3e-22
Hs4507831 [OUT] KOG0595 Serine/threonine-protein kinase involved... 104 3e-22
At1g08650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 104 3e-22
7290150 [T] KOG0583 Serine/threonine protein kinase 104 3e-22
Hs15619015 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 103 4e-22
At5g25110 [T] KOG0583 Serine/threonine protein kinase 103 4e-22
At2g26980 [T] KOG0583 Serine/threonine protein kinase 103 4e-22
At1g01140 [T] KOG0583 Serine/threonine protein kinase 103 4e-22
YPL203w [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 103 6e-22
CE00847 [T] KOG0583 Serine/threonine protein kinase 103 6e-22
At3g17510 [T] KOG0583 Serine/threonine protein kinase 103 6e-22
At2g37840 [OUT] KOG0595 Serine/threonine-protein kinase involved... 103 6e-22
7297542 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 103 6e-22
HsM4505103 [R] KOG0586 Serine/threonine protein kinase 103 8e-22
Hs5453964 [T] KOG0583 Serine/threonine protein kinase 103 8e-22
Hs4506055 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 103 8e-22
Hs16418343 [T] KOG0583 Serine/threonine protein kinase 103 8e-22
At3g08730 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 103 8e-22
7302464 [R] KOG0586 Serine/threonine protein kinase 103 8e-22
At5g12180 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 102 1e-21
At3g08720 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 102 1e-21
At3g01090 [T] KOG0583 Serine/threonine protein kinase 102 1e-21
CE26793_1 [R] KOG0611 Predicted serine/threonine protein kinase 102 1e-21
SPBC12D12.04c [T] KOG0694 Serine/threonine protein kinase 102 2e-21
Hs9845489 [R] KOG0586 Serine/threonine protein kinase 102 2e-21
Hs9845487 [R] KOG0586 Serine/threonine protein kinase 102 2e-21
Hs22062450 [R] KOG0586 Serine/threonine protein kinase 102 2e-21
Hs20547806 [R] KOG0589 Serine/threonine protein kinase 102 2e-21
Hs14042947 [T] KOG0583 Serine/threonine protein kinase 102 2e-21
CE27166 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 102 2e-21
At5g04870 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 102 2e-21
At1g29230 [T] KOG0583 Serine/threonine protein kinase 102 2e-21
7293666 [D] KOG0575 Polo-like serine/threonine protein kinase 102 2e-21
Hs21361101 [T] KOG0607 MAP kinase-interacting kinase and related... 101 2e-21
CE28993 [G] KOG0599 Phosphorylase kinase gamma subunit 101 2e-21
At5g35410 [T] KOG0583 Serine/threonine protein kinase 101 2e-21
At4g24400 [T] KOG0583 Serine/threonine protein kinase 101 2e-21
SPCC4G3.08 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 101 3e-21
CE16081 [T] KOG0583 Serine/threonine protein kinase 101 3e-21
At3g57530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 101 3e-21
7302861 [T] KOG0696 Serine/threonine protein kinase 101 3e-21
YBR028c [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 100 4e-21
7295426 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 100 4e-21
CE21615 [T] KOG0578 p21-activated serine/threonine protein kinase 100 5e-21
At5g19360 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 100 5e-21
SPAC23C11.16 [D] KOG0575 Polo-like serine/threonine protein kinase 100 6e-21
Hs4759044 [T] KOG0612 Rho-associated coiled-coil containing prot... 100 6e-21
Hs20536595 [T] KOG0612 Rho-associated coiled-coil containing pro... 100 6e-21
At3g61960 [OUT] KOG0595 Serine/threonine-protein kinase involved... 100 6e-21
At3g51850 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 100 6e-21
At1g61950 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 100 6e-21
YLR248w [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 100 8e-21
YDR477w [T] KOG0583 Serine/threonine protein kinase 100 8e-21
7293249 [T] KOG0612 Rho-associated coiled-coil containing protei... 100 8e-21
SPBC106.10 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 99 1e-20
Hs7661974 [T] KOG0583 Serine/threonine protein kinase 99 1e-20
Hs19923464 [T] KOG0577 Serine/threonine protein kinase 99 1e-20
Hs16950619 [Z] KOG0613 Projectin/twitchin and related proteins 99 1e-20
At3g29160 [T] KOG0583 Serine/threonine protein kinase 99 1e-20
7301734 [T] KOG0694 Serine/threonine protein kinase 99 1e-20
7300559 [T] KOG4279 Serine/threonine protein kinase 99 1e-20
SPBC17F3.02 [T] KOG0201 Serine/threonine protein kinase 99 1e-20
Hs5453966 [T] KOG0583 Serine/threonine protein kinase 99 1e-20
Hs4758194 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 99 1e-20
CE27670 [T] KOG0578 p21-activated serine/threonine protein kinase 99 1e-20
At5g10930 [T] KOG0583 Serine/threonine protein kinase 99 1e-20
At1g48490 [TR] KOG0606 Microtubule-associated serine/threonine k... 99 1e-20
At4g33950 [T] KOG0583 Serine/threonine protein kinase 99 2e-20
At2g38490 [T] KOG0583 Serine/threonine protein kinase 99 2e-20
At2g17290 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 99 2e-20
At1g78290 [T] KOG0583 Serine/threonine protein kinase 99 2e-20
YNL298w [T] KOG0578 p21-activated serine/threonine protein kinase 98 2e-20
YHL007c [T] KOG0578 p21-activated serine/threonine protein kinase 98 2e-20
YAR019c [T] KOG0198 MEKK and related serine/threonine protein ki... 98 2e-20
Hs7662210 [OUT] KOG0595 Serine/threonine-protein kinase involved... 98 2e-20
Hs21361433 [D] KOG0575 Polo-like serine/threonine protein kinase 98 2e-20
At5g01820 [T] KOG0583 Serine/threonine protein kinase 98 2e-20
HsM7657627 [D] KOG0575 Polo-like serine/threonine protein kinase 98 3e-20
Hs4885583 [T] KOG0612 Rho-associated coiled-coil containing prot... 98 3e-20
CE22045 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 98 3e-20
At4g35310 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 98 3e-20
At4g21940 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 98 3e-20
YOR233w [T] KOG0583 Serine/threonine protein kinase 97 4e-20
Hs7661994 [T] KOG0579 Ste20-like serine/threonine protein kinase 97 4e-20
CE28760 [R] KOG0605 NDR and related serine/threonine kinases 97 4e-20
At3g04530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 97 4e-20
7303860 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 97 4e-20
7296450 [D] KOG0575 Polo-like serine/threonine protein kinase 97 4e-20
At4g38230 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 97 5e-20
Hs5174547 [T] KOG4279 Serine/threonine protein kinase 97 7e-20
Hs20070247_2 [RT] KOG0598 Ribosomal protein S6 kinase and relate... 97 7e-20
7291742_1 [T] KOG0612 Rho-associated coiled-coil containing prot... 97 7e-20
YOL113w [T] KOG0578 p21-activated serine/threonine protein kinase 96 9e-20
Hs14777335 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 96 9e-20
CE14798 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 96 9e-20
At5g08590 [T] KOG0583 Serine/threonine protein kinase 96 9e-20
7300149 [T] KOG0578 p21-activated serine/threonine protein kinase 96 9e-20
Hs20428779_1 [T] KOG0587 Traf2- and Nck-interacting kinase and r... 96 9e-20
CE17284 [T] KOG0583 Serine/threonine protein kinase 96 1e-19
At5g39440 [T] KOG0583 Serine/threonine protein kinase 96 1e-19
At4g08500 [T] KOG0198 MEKK and related serine/threonine protein ... 96 1e-19
At3g06030 [T] KOG0198 MEKK and related serine/threonine protein ... 96 1e-19
At2g34180 [T] KOG0583 Serine/threonine protein kinase 96 1e-19
YDR507c [D] KOG0588 Serine/threonine protein kinase 96 2e-19
YKL166c [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 95 2e-19
YJL164c [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 95 2e-19
Hs13569922 [R] KOG0611 Predicted serine/threonine protein kinase 95 2e-19
At3g23310 [R] KOG0605 NDR and related serine/threonine kinases 95 2e-19
At1g09000 [T] KOG0198 MEKK and related serine/threonine protein ... 95 2e-19
7297776 [D] KOG0580 Serine/threonine protein kinase 95 2e-19
SPAC890.03 [T] KOG0583 Serine/threonine protein kinase 95 3e-19
At1g10940 [T] KOG0583 Serine/threonine protein kinase 95 3e-19
Hs7662170 [R] KOG0611 Predicted serine/threonine protein kinase 94 4e-19
Hs6005814 [R] KOG0605 NDR and related serine/threonine kinases 94 4e-19
Hs5453976 [T] KOG0694 Serine/threonine protein kinase 94 4e-19
Hs4505373 [V] KOG1826 Ras GTPase activating protein RasGAP/neuro... 94 4e-19
Hs21361133 [R] KOG0586 Serine/threonine protein kinase 94 4e-19
CE08098 [T] KOG0612 Rho-associated coiled-coil containing protei... 94 4e-19
CE07285 [D] KOG0575 Polo-like serine/threonine protein kinase 94 4e-19
At1g45160 [TR] KOG0606 Microtubule-associated serine/threonine k... 94 4e-19
YOL100w [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 94 5e-19
Hs7706401 [T] KOG0577 Serine/threonine protein kinase 94 5e-19
Hs5453974 [T] KOG0694 Serine/threonine protein kinase 94 5e-19
Hs4759208 [T] KOG0577 Serine/threonine protein kinase 94 5e-19
Hs20127541 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 94 5e-19
CE03492 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 94 5e-19
At5g63650 [T] KOG0583 Serine/threonine protein kinase 94 5e-19
YHR102w [T] KOG0201 Serine/threonine protein kinase 94 6e-19
SPCC320.12c [D] KOG0580 Serine/threonine protein kinase 94 6e-19
Hs4758702 [T] KOG4279 Serine/threonine protein kinase 94 6e-19
At4g08480 [T] KOG0198 MEKK and related serine/threonine protein ... 94 6e-19
At1g54960 [T] KOG0198 MEKK and related serine/threonine protein ... 94 6e-19
7294217 [D] KOG0588 Serine/threonine protein kinase 94 6e-19
YMR104c [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 93 8e-19
At4g04710 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 93 8e-19
CE02602_1 [T] KOG0660 Mitogen-activated protein kinase 93 8e-19
SPCC74.03c [T] KOG0583 Serine/threonine protein kinase 93 1e-18
SPAC1F5.09c [T] KOG0578 p21-activated serine/threonine protein k... 93 1e-18
Hs20545245 [D] KOG0588 Serine/threonine protein kinase 93 1e-18
CE28479 [T] KOG0583 Serine/threonine protein kinase 93 1e-18
At4g14350 [R] KOG0605 NDR and related serine/threonine kinases 93 1e-18
7303211 [T] KOG4717 Serine/threonine protein kinase 93 1e-18
Hs4507277_1 [R] KOG0589 Serine/threonine protein kinase 93 1e-18
CE28643 [T] KOG0583 Serine/threonine protein kinase 92 1e-18
CE21025 [D] KOG0580 Serine/threonine protein kinase 92 1e-18
CE07458 [T] KOG0583 Serine/threonine protein kinase 92 1e-18
At2g23030 [T] KOG0583 Serine/threonine protein kinase 92 1e-18
At1g50230 [R] KOG0597 Serine-threonine protein kinase FUSED 92 1e-18
Hs4505599 [T] KOG0578 p21-activated serine/threonine protein kinase 92 2e-18
CE26649 [D] KOG0575 Polo-like serine/threonine protein kinase 92 2e-18
7303915 [T] KOG0694 Serine/threonine protein kinase 92 2e-18
7303914 [T] KOG0694 Serine/threonine protein kinase 92 2e-18
7302570 [R] KOG0586 Serine/threonine protein kinase 92 2e-18
Hs16507245 [T] KOG0583 Serine/threonine protein kinase 92 2e-18
CE29092 [T] KOG0694 Serine/threonine protein kinase 92 2e-18
CE24516 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 92 2e-18
At5g62310 [TR] KOG0606 Microtubule-associated serine/threonine k... 92 2e-18
At1g03920 [R] KOG0605 NDR and related serine/threonine kinases 92 2e-18
7299322 [R] KOG0611 Predicted serine/threonine protein kinase 92 2e-18
Hs7657214 [T] KOG0583 Serine/threonine protein kinase 91 3e-18
Hs4505831 [T] KOG0612 Rho-associated coiled-coil containing prot... 91 3e-18
CE11916 [T] KOG0612 Rho-associated coiled-coil containing protei... 91 3e-18
At3g17850 [TR] KOG0606 Microtubule-associated serine/threonine k... 91 3e-18
At1g60940 [T] KOG0583 Serine/threonine protein kinase 91 3e-18
7298926 [T] KOG0578 p21-activated serine/threonine protein kinase 91 3e-18
7293735 [R] KOG0605 NDR and related serine/threonine kinases 91 3e-18
Hs6005922_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 91 3e-18
YCL024w [T] KOG0583 Serine/threonine protein kinase 91 4e-18
SPAC17G8.14c [T] KOG0694 Serine/threonine protein kinase 91 4e-18
Hs20070158 [T] KOG0201 Serine/threonine protein kinase 91 4e-18
7300106 [T] KOG0690 Serine/threonine protein kinase 91 4e-18
Hs4885549 [T] KOG0690 Serine/threonine protein kinase 91 5e-18
At5g66880 [T] KOG0583 Serine/threonine protein kinase 91 5e-18
YPL141c [T] KOG0583 Serine/threonine protein kinase 90 7e-18
YKL126w [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 90 7e-18
YCR091w [R] KOG0610 Putative serine/threonine protein kinase 90 7e-18
Hs4885563 [T] KOG0694 Serine/threonine protein kinase 90 7e-18
Hs19923407 [D] KOG0591 NIMA (never in mitosis)-related G2-specif... 90 7e-18
CE28744 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 90 7e-18
CE15235 [R] KOG0589 Serine/threonine protein kinase 90 7e-18
At3g50500 [T] KOG0583 Serine/threonine protein kinase 90 7e-18
At3g13530 [T] KOG0198 MEKK and related serine/threonine protein ... 90 7e-18
At1g63700 [T] KOG0198 MEKK and related serine/threonine protein ... 90 7e-18
SPAC1F3.02c [T] KOG0198 MEKK and related serine/threonine protei... 90 9e-18
Hs4505695 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 90 9e-18
Hs18579683 [R] KOG0605 NDR and related serine/threonine kinases 90 9e-18
Hs10334852 [T] KOG0612 Rho-associated coiled-coil containing pro... 90 9e-18
CE27177 [T] KOG4279 Serine/threonine protein kinase 90 9e-18
CE17354 [T] KOG0694 Serine/threonine protein kinase 90 9e-18
CE17353 [T] KOG0694 Serine/threonine protein kinase 90 9e-18
CE05274 [T] KOG0690 Serine/threonine protein kinase 90 9e-18
7293601 [T] KOG0577 Serine/threonine protein kinase 90 9e-18
Hs5453970 [T] KOG0694 Serine/threonine protein kinase 89 1e-17
Hs4506071 [T] KOG0695 Serine/threonine protein kinase 89 1e-17
CE15612 [T] KOG0690 Serine/threonine protein kinase 89 1e-17
At1g53570 [T] KOG0198 MEKK and related serine/threonine protein ... 89 1e-17
7294537 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 89 1e-17
Hs4506067 [T] KOG0696 Serine/threonine protein kinase 89 1e-17
Hs14735945 [T] KOG0694 Serine/threonine protein kinase 89 1e-17
CE29300 [T] KOG0694 Serine/threonine protein kinase 89 1e-17
CE29299 [T] KOG0694 Serine/threonine protein kinase 89 1e-17
CE28218 [D] KOG0588 Serine/threonine protein kinase 89 1e-17
CE17343 [T] KOG0583 Serine/threonine protein kinase 89 1e-17
CE12408 [T] KOG0661 MAPK related serine/threonine protein kinase 89 1e-17
YDR122w [T] KOG0583 Serine/threonine protein kinase 89 2e-17
YBL105c [T] KOG0694 Serine/threonine protein kinase 89 2e-17
Hs19424132 [D] KOG0591 NIMA (never in mitosis)-related G2-specif... 89 2e-17
CE03232 [D] KOG0591 NIMA (never in mitosis)-related G2-specific ... 89 2e-17
At4g40010 [T] KOG0583 Serine/threonine protein kinase 89 2e-17
7303111 [T] KOG0695 Serine/threonine protein kinase 89 2e-17
7302860 [T] KOG0696 Serine/threonine protein kinase 89 2e-17
7294566 [T] KOG0612 Rho-associated coiled-coil containing protei... 89 2e-17
Hs5453972 [T] KOG0694 Serine/threonine protein kinase 88 3e-17
Hs4502023 [T] KOG0690 Serine/threonine protein kinase 88 3e-17
At3g15220 [T] KOG0201 Serine/threonine protein kinase 88 3e-17
7300224 [T] KOG0201 Serine/threonine protein kinase 88 3e-17
YLR096w [T] KOG0583 Serine/threonine protein kinase 88 3e-17
HsM5454174 [T] KOG0201 Serine/threonine protein kinase 88 3e-17
Hs4507275 [D] KOG0580 Serine/threonine protein kinase 88 3e-17
Hs22068996 [T] KOG1345 Serine/threonine kinase 88 3e-17
Hs21361358 [T] KOG0201 Serine/threonine protein kinase 88 3e-17
Hs14770402 [R] KOG0586 Serine/threonine protein kinase 88 3e-17
At3g07980 [T] KOG0198 MEKK and related serine/threonine protein ... 88 3e-17
Hs16357474_1 [T] KOG0612 Rho-associated coiled-coil containing p... 88 3e-17
YNR047w [R] KOG0610 Putative serine/threonine protein kinase 87 4e-17
YCR073c [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and r... 87 4e-17
Hs7661946 [T] KOG4250 TANK binding protein kinase TBK1 87 4e-17
Hs4758016 [D] KOG0575 Polo-like serine/threonine protein kinase 87 4e-17
CE22877 [D] KOG0575 Polo-like serine/threonine protein kinase 87 4e-17
7298323 [D] KOG0590 Checkpoint kinase and related serine/threoni... 87 4e-17
Hs9910476 [T] KOG0578 p21-activated serine/threonine protein kinase 87 6e-17
Hs4826878 [T] KOG0582 Ste20-like serine/threonine protein kinase 87 6e-17
Hs22068916 [T] KOG0696 Serine/threonine protein kinase 87 6e-17
Hs20127450 [T] KOG0696 Serine/threonine protein kinase 87 6e-17
CE26212 [T] KOG0582 Ste20-like serine/threonine protein kinase 87 6e-17
At1g53165 [T] KOG0201 Serine/threonine protein kinase 87 6e-17
Hs8393810_1 [T] KOG0587 Traf2- and Nck-interacting kinase and re... 87 6e-17
Hs20544910_1 [T] KOG0587 Traf2- and Nck-interacting kinase and r... 87 6e-17
SPAC9G1.09 [T] KOG0201 Serine/threonine protein kinase 87 7e-17
SPAC9G1.02 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 an... 87 7e-17
HsM4507279 [D] KOG0580 Serine/threonine protein kinase 87 7e-17
Hs18596354 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 87 7e-17
ECU01g0630 [D] KOG0575 Polo-like serine/threonine protein kinase 87 7e-17
CE20564 [T] KOG0578 p21-activated serine/threonine protein kinase 87 7e-17
CE05425 [T] KOG0578 p21-activated serine/threonine protein kinase 87 7e-17
Hs4507273 [D] KOG0580 Serine/threonine protein kinase 86 1e-16
Hs14150045 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 86 1e-16
ECU08g1480 [R] KOG0586 Serine/threonine protein kinase 86 1e-16
CE24761 [D] KOG0580 Serine/threonine protein kinase 86 1e-16
CE18366 [T] KOG0583 Serine/threonine protein kinase 86 1e-16
CE02586 [T] KOG0696 Serine/threonine protein kinase 86 1e-16
7291710 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 86 1e-16
Hs5453978 [T] KOG0614 cGMP-dependent protein kinase 86 1e-16
Hs4506073 [T] KOG0694 Serine/threonine protein kinase 86 1e-16
Hs14758219 [T] KOG0694 Serine/threonine protein kinase 86 1e-16
7301213 [R] KOG0589 Serine/threonine protein kinase 86 1e-16
At4g12020_6 [T] KOG0198 MEKK and related serine/threonine protei... 86 1e-16
YPL150w [T] KOG0583 Serine/threonine protein kinase 86 2e-16
SPBC21.06c [T] KOG0198 MEKK and related serine/threonine protein... 86 2e-16
SPAC644.06c [D] KOG0588 Serine/threonine protein kinase 86 2e-16
Hs20535816 [T] KOG0695 Serine/threonine protein kinase 86 2e-16
Hs16950615 [Z] KOG0613 Projectin/twitchin and related proteins 86 2e-16
Hs10864650 [T] KOG0695 Serine/threonine protein kinase 86 2e-16
CE03467 [T] KOG0604 MAP kinase-activated protein kinase 2 86 2e-16
CE02604 [T] KOG0695 Serine/threonine protein kinase 86 2e-16
At4g32830 [D] KOG0580 Serine/threonine protein kinase 86 2e-16
At2g25880 [D] KOG0580 Serine/threonine protein kinase 86 2e-16
YDR523c [T] KOG0201 Serine/threonine protein kinase 85 2e-16
SPBC1604.14c [T] KOG0578 p21-activated serine/threonine protein ... 85 2e-16
Hs8923754 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 85 2e-16
At1g54510 [R] KOG0589 Serine/threonine protein kinase 85 2e-16
7299536 [D] KOG0580 Serine/threonine protein kinase 85 2e-16
7294265 [TR] KOG0606 Microtubule-associated serine/threonine kin... 85 2e-16
YLR362w [T] KOG0198 MEKK and related serine/threonine protein ki... 85 3e-16
Hs21359873 [D] KOG0575 Polo-like serine/threonine protein kinase 85 3e-16
Hs14042966 [T] KOG0583 Serine/threonine protein kinase 85 3e-16
At5g57630 [T] KOG0583 Serine/threonine protein kinase 85 3e-16
YKL101w [D] KOG0588 Serine/threonine protein kinase 84 4e-16
Hs20562757 [T] KOG0660 Mitogen-activated protein kinase 84 4e-16
Hs15011880 [T] KOG0201 Serine/threonine protein kinase 84 4e-16
Hs14754789 [OUT] KOG0595 Serine/threonine-protein kinase involve... 84 4e-16
CE24971 [T] KOG0660 Mitogen-activated protein kinase 84 4e-16
CE01583 [T] KOG0660 Mitogen-activated protein kinase 84 4e-16
At5g04510 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 84 4e-16
At3g04810 [R] KOG0589 Serine/threonine protein kinase 84 4e-16
SPAC23H4.02 [T] KOG0583 Serine/threonine protein kinase 84 5e-16
Hs4885061 [T] KOG0690 Serine/threonine protein kinase 84 5e-16
CE08355 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 84 5e-16
CE06762 [T] KOG0660 Mitogen-activated protein kinase 84 5e-16
At4g04700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 84 5e-16
At3g20860 [R] KOG0589 Serine/threonine protein kinase 84 5e-16
At2g45490 [D] KOG0580 Serine/threonine protein kinase 84 5e-16
7297080 [T] KOG0583 Serine/threonine protein kinase 84 5e-16
7291778 [T] KOG0579 Ste20-like serine/threonine protein kinase 84 5e-16
SPCC1259.13 [D] KOG0590 Checkpoint kinase and related serine/thr... 84 6e-16
7289880 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 84 6e-16
CE27131_1 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase E... 84 6e-16
SPAC2C4.14c [T] KOG0201 Serine/threonine protein kinase 83 8e-16
Hs7382496 [T] KOG0578 p21-activated serine/threonine protein kinase 83 8e-16
Hs7019543 [T] KOG0582 Ste20-like serine/threonine protein kinase 83 8e-16
Hs21361643 [T] KOG4717 Serine/threonine protein kinase 83 8e-16
Hs16950617 [Z] KOG0613 Projectin/twitchin and related proteins 83 8e-16
CE20493 [TR] KOG0606 Microtubule-associated serine/threonine kin... 83 8e-16
SPBC4F6.06 [T] KOG0583 Serine/threonine protein kinase 83 1e-15
Hs4505601 [T] KOG0578 p21-activated serine/threonine protein kinase 83 1e-15
Hs22035600 [T] KOG0576 Mitogen-activated protein kinase kinase k... 83 1e-15
CE29298 [T] KOG0690 Serine/threonine protein kinase 83 1e-15
CE18646 [T] KOG0690 Serine/threonine protein kinase 83 1e-15
At3g50730 [T] KOG0192 Tyrosine kinase specific for activated (GT... 83 1e-15
7301971 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 83 1e-15
HsM4826916 [D] KOG0575 Polo-like serine/threonine protein kinase 82 1e-15
CE21239 [T] KOG0583 Serine/threonine protein kinase 82 1e-15
At5g28290 [R] KOG0589 Serine/threonine protein kinase 82 1e-15
At3g50720 [T] KOG0192 Tyrosine kinase specific for activated (GT... 82 1e-15
At3g10540 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 82 1e-15
SPBC1861.09 [R] KOG0610 Putative serine/threonine protein kinase 82 2e-15
HsM4759010 [T] KOG0576 Mitogen-activated protein kinase kinase k... 82 2e-15
Hs4505153 [T] KOG0198 MEKK and related serine/threonine protein ... 82 2e-15
CE27573 [T] KOG0198 MEKK and related serine/threonine protein ki... 82 2e-15
CE07737 [T] KOG0198 MEKK and related serine/threonine protein ki... 82 2e-15
At5g50180 [T] KOG0192 Tyrosine kinase specific for activated (GT... 82 2e-15
7298698 [T] KOG4250 TANK binding protein kinase TBK1 82 2e-15
SPCC297.03 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 82 2e-15
Hs20538863 [T] KOG4250 TANK binding protein kinase TBK1 82 2e-15
Hs14771959 [T] KOG0578 p21-activated serine/threonine protein ki... 82 2e-15
Hs13384594 [T] KOG0696 Serine/threonine protein kinase 82 2e-15
ECU01g1320 [T] KOG0612 Rho-associated coiled-coil containing pro... 82 2e-15
CE23001 [R] KOG0589 Serine/threonine protein kinase 82 2e-15
CE19294 [T] KOG0198 MEKK and related serine/threonine protein ki... 82 2e-15
CE18699 [T] KOG0694 Serine/threonine protein kinase 82 2e-15
At1g51660 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 82 2e-15
Hs7662388 [T] KOG0661 MAPK related serine/threonine protein kinase 81 3e-15
CE13844 [D] KOG0608 Warts/lats-like serine threonine kinases 81 3e-15
At4g08470 [T] KOG0198 MEKK and related serine/threonine protein ... 81 3e-15
>YOR351c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 497
Score = 465 bits (1196), Expect = e-131
Identities = 245/455 (53%), Positives = 322/455 (69%), Gaps = 27/455 (5%)
Query: 32 NKVLKLGRNTEECIYSVEHPSVSNIHCVLWGIRFDPESVPLCYIKDMSLNGTMVNEQVLS 91
++++K+GRN +EC + +PS+S++HCV W + FD +S+P+ Y+KD SLNGT +N +L
Sbjct: 44 HQLVKVGRNDKECQLVLTNPSISSVHCVFWCVFFDEDSIPMFYVKDCSLNGTYLNGLLLK 103
Query: 92 RDVPYLLSNQDVIQLPNGAK----------FKFSA-VKSETMSQFMTGLRIKSEWDRWKI 140
RD YLL + DVI+L G++ F + ++S + + + E D+W+I
Sbjct: 104 RDKTYLLKHCDVIELSQGSEENDIKKTRLVFMINDDLQSSLDPKLLDQMGFLREVDQWEI 163
Query: 141 VPRIVGSGTFGHVLVAEKVDHNMKRQ---VAKKTVSYAVKVINTAKTRMVKEATILEKLN 197
RIVG+GTFGHVL+ HN K + V +YAVK+I + KEA IL +L+
Sbjct: 164 TNRIVGNGTFGHVLIT----HNSKERDEDVCYHPENYAVKIIKLKPNKFDKEARILLRLD 219
Query: 198 HPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALK 257
HPNII+++ + D ++YIFQDLI GGDLFSYLAKGDCL +SETESL+I++QIL AL
Sbjct: 220 HPNIIKVYHTFCDRNNHLYIFQDLIPGGDLFSYLAKGDCLTSMSETESLLIVFQILQALN 279
Query: 258 FLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPE 317
+LH IVHRDLKLDNILL TPEPCT++VLADFGIAK+L+ N KERMHTVVGTPEYCAPE
Sbjct: 280 YLHDQDIVHRDLKLDNILLCTPEPCTRIVLADFGIAKDLNSN-KERMHTVVGTPEYCAPE 338
Query: 318 VGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIK 377
VGF+A+R Y+SFSR ATL + GYDSKCD+WSLGVITHIMLTGISPFYGDGSE SII+
Sbjct: 339 VGFRANRKAYQSFSRAATL--EQRGYDSKCDLWSLGVITHIMLTGISPFYGDGSERSIIQ 396
Query: 378 NVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKHTSQLERIYK 437
N + GKLNF +QW ++D+AKSFVK LQ R + ++ L +W+ KH SQLER+Y
Sbjct: 397 NAKIGKLNFKLKQWDIVSDNAKSFVKDLLQTDVVKRLNSKQGLKHIWIAKHLSQLERLYY 456
Query: 438 KKVLQLSSDCIKIDE-NIDTFAVVKHKLPKSVKLS 471
KK+L +++ K++ N D K KLPKSV +S
Sbjct: 457 KKIL-CNNEGPKLESINSDW----KRKLPKSVIIS 486
>SPAC14C4.03 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 445
Score = 216 bits (549), Expect = 8e-56
Identities = 138/426 (32%), Positives = 239/426 (55%), Gaps = 36/426 (8%)
Query: 18 SSPQFIVNHFQIEINKVLKLGRNTEECIYSVEHPSVSNIHCVLWGIRFDPESVPLCYIKD 77
SSPQ ++N ++ + + +GR+ C Y + + S H ++ + D + PL Y +D
Sbjct: 48 SSPQTVLN---VKKYEDVSVGRSNT-CNYQLLQFTASYKHFRVYSVLIDDDMDPLVYCED 103
Query: 78 MSLNGTMVNEQVLSRDVPYLLSNQDVIQLPNGAKFKFSAVKSETMSQFMTGLRIKSEWDR 137
S NGT +N +++ + LLS+ D++ + + A F F K T + F + +R
Sbjct: 104 QSSNGTFLNHRLIGKGNSVLLSDGDILDVRHCASFLFQQ-KYTTDNDF----HHEYAGER 158
Query: 138 WKIVPRIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKLN 197
+ I R++G G F + +A +D+N Q A K + K I+T + E TIL KL+
Sbjct: 159 FNITQRLLGIGGFSRIYMA--MDNNTGGQYACKIIDK--KKISTKRFFEDHEMTILRKLD 214
Query: 198 HPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALK 257
HPNII+++ ++ +IF+++++GGDLFSYL K L + E +L I++QIL LK
Sbjct: 215 HPNIIKVNME-YNSETQFFIFEEMVTGGDLFSYLTK---LGTVPEVTTLFIMFQILQGLK 270
Query: 258 FLHSNGIVHRDLKLDNILL-HTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAP 316
+LH I+HRDLKL+NIL+ + + +++L DFG+A+ + + +R+ T VGTPEY AP
Sbjct: 271 YLHEQNIIHRDLKLENILIASSSDTIFRIILTDFGVARCMQKG--KRLSTFVGTPEYTAP 328
Query: 317 EVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASII 376
E I R R+ +++GY + D+WSLGVI ++L+G SP + DG
Sbjct: 329 E--------IQRLKGRSQVEKENSSGYGKEVDLWSLGVIMFLLLSGNSPSFADG------ 374
Query: 377 KNVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKHTSQLERIY 436
V+ +++F W +++ AK + L+ + +R V++ L W +H+S+L ++Y
Sbjct: 375 --VKEKQVDFRDPVWKSVSRQAKDLISNLLKTNPPDRFTVKQCLSHPWFARHSSRLTKLY 432
Query: 437 KKKVLQ 442
+ ++L+
Sbjct: 433 ETRILK 438
>Hs6005850 [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 543
Score = 162 bits (409), Expect = 1e-39
Identities = 121/367 (32%), Positives = 182/367 (48%), Gaps = 38/367 (10%)
Query: 67 PESVPLCYIKDMSLNGTMVNEQVLSRDVPYLLSNQDVI--QLPNGAKFKFSAVKSETMSQ 124
P++ + YI+D S NGT VN +++ + L+N I L F F + + S
Sbjct: 152 PKNSYIAYIEDHSGNGTFVNTELVGKGKRRPLNNNSEIALSLSRNKVFVFFDLTVDDQSV 211
Query: 125 FMTGLRIKSEWDRWKIVPRIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKT 184
+ LR D + I+ + +GSG G V +A + ++VA K +S I +A+
Sbjct: 212 YPKALR-----DEY-IMSKTLGSGACGEVKLA--FERKTCKKVAIKIISKRKFAIGSARE 263
Query: 185 -----RMVKEATILEKLNHPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVP 239
+ E IL+KLNHP II+I ++ DA + YI +L+ GG+LF + L
Sbjct: 264 ADPALNVETEIEILKKLNHPCIIKI-KNFFDA-EDYYIVLELMEGGELFDKVVGNKRL-- 319
Query: 240 ISETESLIIIYQILLALKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQN 299
E + YQ+LLA+++LH NGI+HRDLK +N+LL + E + + DFG +K L +
Sbjct: 320 -KEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGET 378
Query: 300 TKERMHTVVGTPEYCAPEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIM 359
+ M T+ GTP Y APEV + GY+ D WSLGVI I
Sbjct: 379 SL--MRTLCGTPTYLAPEV----------------LVSVGTAGYNRAVDCWSLGVILFIC 420
Query: 360 LTGISPFYGDGSEASIIKNVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEA 419
L+G PF ++ S+ + +GK NF W +++ A VKK L V R EEA
Sbjct: 421 LSGYPPFSEHRTQVSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEA 480
Query: 420 LHQVWVE 426
L W++
Sbjct: 481 LRHPWLQ 487
>7298652 [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 459
Score = 152 bits (384), Expect = 1e-36
Identities = 114/379 (30%), Positives = 184/379 (48%), Gaps = 37/379 (9%)
Query: 53 VSNIHCVLWGIRFDPESVPLCYIKDMSLNGTMVNEQVLSRDVPYLLSNQDVIQLPNGAKF 112
+S +H ++ R + E YI+D+S NGT VN + + + +L N DVI L + +
Sbjct: 77 ISKVHFIIK--RANCELTNPVYIQDLSRNGTFVNNEKIGTNRMRILKNDDVISLSHPT-Y 133
Query: 113 KFSAVKSETMSQFMTGLRIKSEWDRWKIVPRIVGSGTFGHVLVAEKVDHNMKRQVAKKTV 172
K K + ++ + + E ++ V R +GSG +G LV D +Q A K V
Sbjct: 134 KAFVFKDLSPNE---SIGLPEEINKTYYVNRKLGSGAYG--LVRLVYDTRTCQQFAMKIV 188
Query: 173 SYAVKVINTAKT------RMVKEATILEKLNHPNIIRIHQSCVDALGNVYIFQDLISGGD 226
+ T R++ EA I++ L+HP ++R+H VD +VY+ + + GGD
Sbjct: 189 KKNMLSGARPSTNFSDPDRVLNEAKIMKNLSHPCVVRMHD-IVDKPDSVYMVLEFMRGGD 247
Query: 227 LFSYLAKGDCLVPISETESLIIIYQILLALKFLHSNGIVHRDLKLDNILLHTPEPCTKVV 286
L + + L SE S + YQ+ A+K+LH GI HRDLK DN+LL T + T +
Sbjct: 248 LLNRIISNKLL---SEDISKLYFYQMCHAVKYLHDRGITHRDLKPDNVLLETNDEETLLK 304
Query: 287 LADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKADRNIYRSFSRTATLDPDNNGYDSK 346
++DFG++K + +++ M T+ GTP Y APEV R Y K
Sbjct: 305 VSDFGLSKFVQKDSV--MRTLCGTPLYVAPEVLITGGR----------------EAYTKK 346
Query: 347 CDIWSLGVITHIMLTGISPFYGDGSEASIIKNVRTGKLNFTARQWIAITDSAKSFVKKCL 406
DIWSLGV+ L+G PF D + ++ G+ + W +++ AK + + L
Sbjct: 347 VDIWSLGVVLFTCLSGTLPF-SDEYGTPAAQQIKKGRFAYGHPSWKSVSQRAKLLINQML 405
Query: 407 QVSTFNRCDVEEALHQVWV 425
V R +++ L W+
Sbjct: 406 IVDPERRPSIDDVLQSSWL 424
>Hs4502553 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 370
Score = 150 bits (380), Expect = 3e-36
Identities = 95/321 (29%), Positives = 168/321 (51%), Gaps = 32/321 (9%)
Query: 144 IVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKLNHPNIIR 203
++G+G F V++AE D ++ VA K + A + + + M E +L K+ HPNI+
Sbjct: 25 VLGTGAFSEVILAE--DKRTQKLVAIKCI--AKEALEGKEGSMENEIAVLHKIKHPNIVA 80
Query: 204 IHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHSNG 263
+ ++ G++Y+ L+SGG+LF + + +E ++ +I+Q+L A+K+LH G
Sbjct: 81 L-DDIYESGGHLYLIMQLVSGGELFDRIVEKGFY---TERDASRLIFQVLDAVKYLHDLG 136
Query: 264 IVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKAD 323
IVHRDLK +N+L ++ + +K++++DFG++K ++ + T GTP Y APEV
Sbjct: 137 IVHRDLKPENLLYYSLDEDSKIMISDFGLSK--MEDPGSVLSTACGTPGYVAPEV----- 189
Query: 324 RNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVRTGK 383
Y D WS+GVI +I+L G PFY D ++A + + + +
Sbjct: 190 --------------LAQKPYSKAVDCWSIGVIAYILLCGYPPFY-DENDAKLFEQILKAE 234
Query: 384 LNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKHTSQLERIYKKKVLQL 443
F + W I+DSAK F++ ++ R E+AL W+ T+ + I++ Q+
Sbjct: 235 YEFDSPYWDDISDSAKDFIRHLMEKDPEKRFTCEQALQHPWIAGDTALDKNIHQSVSEQI 294
Query: 444 SSDCIKI--DENIDTFAVVKH 462
+ K + + AVV+H
Sbjct: 295 KKNFAKSKWKQAFNATAVVRH 315
>Hs14196445 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 476
Score = 150 bits (380), Expect = 3e-36
Identities = 102/329 (31%), Positives = 169/329 (51%), Gaps = 42/329 (12%)
Query: 140 IVPRIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAK----TRMVKEATILEK 195
I ++GSG F V + +K+++ K +A+K I + + + E +L+K
Sbjct: 24 IFMEVLGSGAFSEVFL-------VKQRLTGKL--FALKCIKKSPAFRDSSLENEIAVLKK 74
Query: 196 LNHPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLA 255
+ H NI+ + + ++ + Y+ L+SGG+LF + + +E ++ ++I Q+L A
Sbjct: 75 IKHENIVTL-EDIYESTTHYYLVMQLVSGGELFDRILERGVY---TEKDASLVIQQVLSA 130
Query: 256 LKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCA 315
+K+LH NGIVHRDLK +N+L TPE +K+++ DFG++K + QN M T GTP Y A
Sbjct: 131 VKYLHENGIVHRDLKPENLLYLTPEENSKIMITDFGLSK-MEQN--GIMSTACGTPGYVA 187
Query: 316 PEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASI 375
PEV Y D WS+GVIT+I+L G PFY + +E+ +
Sbjct: 188 PEV-------------------LAQKPYSKAVDCWSIGVITYILLCGYPPFY-EETESKL 227
Query: 376 IKNVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKHTSQLERI 435
+ ++ G F + W I++SAK F+ L+ R E+AL W++ +T+ I
Sbjct: 228 FEKIKEGYYEFESPFWDDISESAKDFICHLLEKDPNERYTCEKALSHPWIDGNTALHRDI 287
Query: 436 YKKKVLQLSSDCIKID--ENIDTFAVVKH 462
Y LQ+ + K + + AVV H
Sbjct: 288 YPSVSLQIQKNFAKSKWRQAFNAAAVVHH 316
>CE28061 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 302
Score = 148 bits (373), Expect = 2e-35
Identities = 101/294 (34%), Positives = 151/294 (51%), Gaps = 37/294 (12%)
Query: 163 MKRQVAKKT-VSYAVKVINTAKT------RMVKEATILEKLNHPNIIRIHQSCVDALGNV 215
++R V K T + +A K+INT K ++ +EA I KL HPNI+R+H S + +
Sbjct: 26 VRRCVHKTTGLEFAAKIINTKKLSARDFQKLEREARICRKLQHPNIVRLHDSIQEESFHY 85
Query: 216 YIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHSNGIVHRDLKLDNIL 275
+F DL++GG+LF + + SE ++ I QIL ++ + HSNGIVHRDLK +N+L
Sbjct: 86 LVF-DLVTGGELFEDIVAREFY---SEADASHCIQQILESIAYCHSNGIVHRDLKPENLL 141
Query: 276 LHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKADRNIYRSFSRTAT 335
L + V LADFG+A E+ N E H GTP Y +PEV K
Sbjct: 142 LASKAKGAAVKLADFGLAIEV--NDSEAWHGFAGTPGYLSPEVLKK-------------- 185
Query: 336 LDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVRTGKLNFTARQWIAIT 395
DP Y DIW+ GVI +I+L G PF+ D + + ++ G ++ + +W +T
Sbjct: 186 -DP----YSKPVDIWACGVILYILLVGYPPFW-DEDQHRLYAQIKAGAYDYPSPEWDTVT 239
Query: 396 DSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKHTSQLERIYKKKVLQLSSDCIK 449
AKS + L V+ R ++AL W+ ER+ Q + DC+K
Sbjct: 240 PEAKSLIDSMLTVNPKKRITADQALKVPWI----CNRERVASAIHRQDTVDCLK 289
>CE28060 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 302
Score = 148 bits (373), Expect = 2e-35
Identities = 101/294 (34%), Positives = 151/294 (51%), Gaps = 37/294 (12%)
Query: 163 MKRQVAKKT-VSYAVKVINTAKT------RMVKEATILEKLNHPNIIRIHQSCVDALGNV 215
++R V K T + +A K+INT K ++ +EA I KL HPNI+R+H S + +
Sbjct: 26 VRRCVHKTTGLEFAAKIINTKKLSARDFQKLEREARICRKLQHPNIVRLHDSIQEESFHY 85
Query: 216 YIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHSNGIVHRDLKLDNIL 275
+F DL++GG+LF + + SE ++ I QIL ++ + HSNGIVHRDLK +N+L
Sbjct: 86 LVF-DLVTGGELFEDIVAREFY---SEADASHCIQQILESIAYCHSNGIVHRDLKPENLL 141
Query: 276 LHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKADRNIYRSFSRTAT 335
L + V LADFG+A E+ N E H GTP Y +PEV K
Sbjct: 142 LASKAKGAAVKLADFGLAIEV--NDSEAWHGFAGTPGYLSPEVLKK-------------- 185
Query: 336 LDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVRTGKLNFTARQWIAIT 395
DP Y DIW+ GVI +I+L G PF+ D + + ++ G ++ + +W +T
Sbjct: 186 -DP----YSKPVDIWACGVILYILLVGYPPFW-DEDQHRLYAQIKAGAYDYPSPEWDTVT 239
Query: 396 DSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKHTSQLERIYKKKVLQLSSDCIK 449
AKS + L V+ R ++AL W+ ER+ Q + DC+K
Sbjct: 240 PEAKSLIDSMLTVNPKKRITADQALKVPWI----CNRERVASAIHRQDTVDCLK 289
>CE28059 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 350
Score = 148 bits (373), Expect = 2e-35
Identities = 101/294 (34%), Positives = 151/294 (51%), Gaps = 37/294 (12%)
Query: 163 MKRQVAKKT-VSYAVKVINTAKT------RMVKEATILEKLNHPNIIRIHQSCVDALGNV 215
++R V K T + +A K+INT K ++ +EA I KL HPNI+R+H S + +
Sbjct: 26 VRRCVHKTTGLEFAAKIINTKKLSARDFQKLEREARICRKLQHPNIVRLHDSIQEESFHY 85
Query: 216 YIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHSNGIVHRDLKLDNIL 275
+F DL++GG+LF + + SE ++ I QIL ++ + HSNGIVHRDLK +N+L
Sbjct: 86 LVF-DLVTGGELFEDIVAREFY---SEADASHCIQQILESIAYCHSNGIVHRDLKPENLL 141
Query: 276 LHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKADRNIYRSFSRTAT 335
L + V LADFG+A E+ N E H GTP Y +PEV K
Sbjct: 142 LASKAKGAAVKLADFGLAIEV--NDSEAWHGFAGTPGYLSPEVLKK-------------- 185
Query: 336 LDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVRTGKLNFTARQWIAIT 395
DP Y DIW+ GVI +I+L G PF+ D + + ++ G ++ + +W +T
Sbjct: 186 -DP----YSKPVDIWACGVILYILLVGYPPFW-DEDQHRLYAQIKAGAYDYPSPEWDTVT 239
Query: 396 DSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKHTSQLERIYKKKVLQLSSDCIK 449
AKS + L V+ R ++AL W+ ER+ Q + DC+K
Sbjct: 240 PEAKSLIDSMLTVNPKKRITADQALKVPWI----CNRERVASAIHRQDTVDCLK 289
>CE28058 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 571
Score = 148 bits (373), Expect = 2e-35
Identities = 101/294 (34%), Positives = 151/294 (51%), Gaps = 37/294 (12%)
Query: 163 MKRQVAKKT-VSYAVKVINTAKT------RMVKEATILEKLNHPNIIRIHQSCVDALGNV 215
++R V K T + +A K+INT K ++ +EA I KL HPNI+R+H S + +
Sbjct: 26 VRRCVHKTTGLEFAAKIINTKKLSARDFQKLEREARICRKLQHPNIVRLHDSIQEESFHY 85
Query: 216 YIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHSNGIVHRDLKLDNIL 275
+F DL++GG+LF + + SE ++ I QIL ++ + HSNGIVHRDLK +N+L
Sbjct: 86 LVF-DLVTGGELFEDIVAREFY---SEADASHCIQQILESIAYCHSNGIVHRDLKPENLL 141
Query: 276 LHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKADRNIYRSFSRTAT 335
L + V LADFG+A E+ N E H GTP Y +PEV K
Sbjct: 142 LASKAKGAAVKLADFGLAIEV--NDSEAWHGFAGTPGYLSPEVLKK-------------- 185
Query: 336 LDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVRTGKLNFTARQWIAIT 395
DP Y DIW+ GVI +I+L G PF+ D + + ++ G ++ + +W +T
Sbjct: 186 -DP----YSKPVDIWACGVILYILLVGYPPFW-DEDQHRLYAQIKAGAYDYPSPEWDTVT 239
Query: 396 DSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKHTSQLERIYKKKVLQLSSDCIK 449
AKS + L V+ R ++AL W+ ER+ Q + DC+K
Sbjct: 240 PEAKSLIDSMLTVNPKKRITADQALKVPWI----CNRERVASAIHRQDTVDCLK 289
>CE28057 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 520
Score = 148 bits (373), Expect = 2e-35
Identities = 101/294 (34%), Positives = 151/294 (51%), Gaps = 37/294 (12%)
Query: 163 MKRQVAKKT-VSYAVKVINTAKT------RMVKEATILEKLNHPNIIRIHQSCVDALGNV 215
++R V K T + +A K+INT K ++ +EA I KL HPNI+R+H S + +
Sbjct: 26 VRRCVHKTTGLEFAAKIINTKKLSARDFQKLEREARICRKLQHPNIVRLHDSIQEESFHY 85
Query: 216 YIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHSNGIVHRDLKLDNIL 275
+F DL++GG+LF + + SE ++ I QIL ++ + HSNGIVHRDLK +N+L
Sbjct: 86 LVF-DLVTGGELFEDIVAREFY---SEADASHCIQQILESIAYCHSNGIVHRDLKPENLL 141
Query: 276 LHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKADRNIYRSFSRTAT 335
L + V LADFG+A E+ N E H GTP Y +PEV K
Sbjct: 142 LASKAKGAAVKLADFGLAIEV--NDSEAWHGFAGTPGYLSPEVLKK-------------- 185
Query: 336 LDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVRTGKLNFTARQWIAIT 395
DP Y DIW+ GVI +I+L G PF+ D + + ++ G ++ + +W +T
Sbjct: 186 -DP----YSKPVDIWACGVILYILLVGYPPFW-DEDQHRLYAQIKAGAYDYPSPEWDTVT 239
Query: 396 DSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKHTSQLERIYKKKVLQLSSDCIK 449
AKS + L V+ R ++AL W+ ER+ Q + DC+K
Sbjct: 240 PEAKSLIDSMLTVNPKKRITADQALKVPWI----CNRERVASAIHRQDTVDCLK 289
>CE28056 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 518
Score = 148 bits (373), Expect = 2e-35
Identities = 101/294 (34%), Positives = 151/294 (51%), Gaps = 37/294 (12%)
Query: 163 MKRQVAKKT-VSYAVKVINTAKT------RMVKEATILEKLNHPNIIRIHQSCVDALGNV 215
++R V K T + +A K+INT K ++ +EA I KL HPNI+R+H S + +
Sbjct: 26 VRRCVHKTTGLEFAAKIINTKKLSARDFQKLEREARICRKLQHPNIVRLHDSIQEESFHY 85
Query: 216 YIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHSNGIVHRDLKLDNIL 275
+F DL++GG+LF + + SE ++ I QIL ++ + HSNGIVHRDLK +N+L
Sbjct: 86 LVF-DLVTGGELFEDIVAREFY---SEADASHCIQQILESIAYCHSNGIVHRDLKPENLL 141
Query: 276 LHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKADRNIYRSFSRTAT 335
L + V LADFG+A E+ N E H GTP Y +PEV K
Sbjct: 142 LASKAKGAAVKLADFGLAIEV--NDSEAWHGFAGTPGYLSPEVLKK-------------- 185
Query: 336 LDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVRTGKLNFTARQWIAIT 395
DP Y DIW+ GVI +I+L G PF+ D + + ++ G ++ + +W +T
Sbjct: 186 -DP----YSKPVDIWACGVILYILLVGYPPFW-DEDQHRLYAQIKAGAYDYPSPEWDTVT 239
Query: 396 DSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKHTSQLERIYKKKVLQLSSDCIK 449
AKS + L V+ R ++AL W+ ER+ Q + DC+K
Sbjct: 240 PEAKSLIDSMLTVNPKKRITADQALKVPWI----CNRERVASAIHRQDTVDCLK 289
>CE28055 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 533
Score = 148 bits (373), Expect = 2e-35
Identities = 101/294 (34%), Positives = 151/294 (51%), Gaps = 37/294 (12%)
Query: 163 MKRQVAKKT-VSYAVKVINTAKT------RMVKEATILEKLNHPNIIRIHQSCVDALGNV 215
++R V K T + +A K+INT K ++ +EA I KL HPNI+R+H S + +
Sbjct: 26 VRRCVHKTTGLEFAAKIINTKKLSARDFQKLEREARICRKLQHPNIVRLHDSIQEESFHY 85
Query: 216 YIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHSNGIVHRDLKLDNIL 275
+F DL++GG+LF + + SE ++ I QIL ++ + HSNGIVHRDLK +N+L
Sbjct: 86 LVF-DLVTGGELFEDIVAREFY---SEADASHCIQQILESIAYCHSNGIVHRDLKPENLL 141
Query: 276 LHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKADRNIYRSFSRTAT 335
L + V LADFG+A E+ N E H GTP Y +PEV K
Sbjct: 142 LASKAKGAAVKLADFGLAIEV--NDSEAWHGFAGTPGYLSPEVLKK-------------- 185
Query: 336 LDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVRTGKLNFTARQWIAIT 395
DP Y DIW+ GVI +I+L G PF+ D + + ++ G ++ + +W +T
Sbjct: 186 -DP----YSKPVDIWACGVILYILLVGYPPFW-DEDQHRLYAQIKAGAYDYPSPEWDTVT 239
Query: 396 DSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKHTSQLERIYKKKVLQLSSDCIK 449
AKS + L V+ R ++AL W+ ER+ Q + DC+K
Sbjct: 240 PEAKSLIDSMLTVNPKKRITADQALKVPWI----CNRERVASAIHRQDTVDCLK 289
>CE28054 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 482
Score = 148 bits (373), Expect = 2e-35
Identities = 101/294 (34%), Positives = 151/294 (51%), Gaps = 37/294 (12%)
Query: 163 MKRQVAKKT-VSYAVKVINTAKT------RMVKEATILEKLNHPNIIRIHQSCVDALGNV 215
++R V K T + +A K+INT K ++ +EA I KL HPNI+R+H S + +
Sbjct: 26 VRRCVHKTTGLEFAAKIINTKKLSARDFQKLEREARICRKLQHPNIVRLHDSIQEESFHY 85
Query: 216 YIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHSNGIVHRDLKLDNIL 275
+F DL++GG+LF + + SE ++ I QIL ++ + HSNGIVHRDLK +N+L
Sbjct: 86 LVF-DLVTGGELFEDIVAREFY---SEADASHCIQQILESIAYCHSNGIVHRDLKPENLL 141
Query: 276 LHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKADRNIYRSFSRTAT 335
L + V LADFG+A E+ N E H GTP Y +PEV K
Sbjct: 142 LASKAKGAAVKLADFGLAIEV--NDSEAWHGFAGTPGYLSPEVLKK-------------- 185
Query: 336 LDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVRTGKLNFTARQWIAIT 395
DP Y DIW+ GVI +I+L G PF+ D + + ++ G ++ + +W +T
Sbjct: 186 -DP----YSKPVDIWACGVILYILLVGYPPFW-DEDQHRLYAQIKAGAYDYPSPEWDTVT 239
Query: 396 DSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKHTSQLERIYKKKVLQLSSDCIK 449
AKS + L V+ R ++AL W+ ER+ Q + DC+K
Sbjct: 240 PEAKSLIDSMLTVNPKKRITADQALKVPWI----CNRERVASAIHRQDTVDCLK 289
>CE28053 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 720
Score = 148 bits (373), Expect = 2e-35
Identities = 101/294 (34%), Positives = 151/294 (51%), Gaps = 37/294 (12%)
Query: 163 MKRQVAKKT-VSYAVKVINTAKT------RMVKEATILEKLNHPNIIRIHQSCVDALGNV 215
++R V K T + +A K+INT K ++ +EA I KL HPNI+R+H S + +
Sbjct: 26 VRRCVHKTTGLEFAAKIINTKKLSARDFQKLEREARICRKLQHPNIVRLHDSIQEESFHY 85
Query: 216 YIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHSNGIVHRDLKLDNIL 275
+F DL++GG+LF + + SE ++ I QIL ++ + HSNGIVHRDLK +N+L
Sbjct: 86 LVF-DLVTGGELFEDIVAREFY---SEADASHCIQQILESIAYCHSNGIVHRDLKPENLL 141
Query: 276 LHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKADRNIYRSFSRTAT 335
L + V LADFG+A E+ N E H GTP Y +PEV K
Sbjct: 142 LASKAKGAAVKLADFGLAIEV--NDSEAWHGFAGTPGYLSPEVLKK-------------- 185
Query: 336 LDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVRTGKLNFTARQWIAIT 395
DP Y DIW+ GVI +I+L G PF+ D + + ++ G ++ + +W +T
Sbjct: 186 -DP----YSKPVDIWACGVILYILLVGYPPFW-DEDQHRLYAQIKAGAYDYPSPEWDTVT 239
Query: 396 DSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKHTSQLERIYKKKVLQLSSDCIK 449
AKS + L V+ R ++AL W+ ER+ Q + DC+K
Sbjct: 240 PEAKSLIDSMLTVNPKKRITADQALKVPWI----CNRERVASAIHRQDTVDCLK 289
>CE28051 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 559
Score = 148 bits (373), Expect = 2e-35
Identities = 101/294 (34%), Positives = 151/294 (51%), Gaps = 37/294 (12%)
Query: 163 MKRQVAKKT-VSYAVKVINTAKT------RMVKEATILEKLNHPNIIRIHQSCVDALGNV 215
++R V K T + +A K+INT K ++ +EA I KL HPNI+R+H S + +
Sbjct: 26 VRRCVHKTTGLEFAAKIINTKKLSARDFQKLEREARICRKLQHPNIVRLHDSIQEESFHY 85
Query: 216 YIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHSNGIVHRDLKLDNIL 275
+F DL++GG+LF + + SE ++ I QIL ++ + HSNGIVHRDLK +N+L
Sbjct: 86 LVF-DLVTGGELFEDIVAREFY---SEADASHCIQQILESIAYCHSNGIVHRDLKPENLL 141
Query: 276 LHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKADRNIYRSFSRTAT 335
L + V LADFG+A E+ N E H GTP Y +PEV K
Sbjct: 142 LASKAKGAAVKLADFGLAIEV--NDSEAWHGFAGTPGYLSPEVLKK-------------- 185
Query: 336 LDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVRTGKLNFTARQWIAIT 395
DP Y DIW+ GVI +I+L G PF+ D + + ++ G ++ + +W +T
Sbjct: 186 -DP----YSKPVDIWACGVILYILLVGYPPFW-DEDQHRLYAQIKAGAYDYPSPEWDTVT 239
Query: 396 DSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKHTSQLERIYKKKVLQLSSDCIK 449
AKS + L V+ R ++AL W+ ER+ Q + DC+K
Sbjct: 240 PEAKSLIDSMLTVNPKKRITADQALKVPWI----CNRERVASAIHRQDTVDCLK 289
>CE25046 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 348
Score = 142 bits (359), Expect = 9e-34
Identities = 93/307 (30%), Positives = 152/307 (49%), Gaps = 32/307 (10%)
Query: 144 IVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKLNHPNIIR 203
++G+G F V +AE + + A K + K + + + E +L KL H NI++
Sbjct: 27 VLGTGAFSKVFLAESKS-DAGQMYAVKCIDK--KALKGKEESLENEIKVLRKLRHNNIVQ 83
Query: 204 IHQSCVDALGNVYIFQDLISGGDLFSYL-AKGDCLVPISETESLIIIYQILLALKFLHSN 262
+ + D VY+ +L++GG+LF + AKG +E ++ +I Q+L A+ F+H N
Sbjct: 84 LFDT-YDEKQFVYLVMELVTGGELFDRIVAKGS----YTEQDASNLIRQVLEAVGFMHDN 138
Query: 263 GIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKA 322
G+VHRDLK +N+L + + +K++++DFG++K M T GTP Y APEV
Sbjct: 139 GVVHRDLKPENLLYYNQDEDSKIMISDFGLSKTEDSGV---MATACGTPGYVAPEV---- 191
Query: 323 DRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVRTG 382
Y D+WS+GVI +I+L G PFY D S+A++ + G
Sbjct: 192 ---------------LQQKPYGKAVDVWSIGVIAYILLCGYPPFY-DESDANLFAQIIKG 235
Query: 383 KLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKHTSQLERIYKKKVLQ 442
+ F A W I+DSAK F+ + R ++AL W+ +T+ I+ +
Sbjct: 236 EYEFDAPYWDQISDSAKDFITHLMCCDPEARFTCQDALSHPWISGNTAYTHDIHGTVAVH 295
Query: 443 LSSDCIK 449
L K
Sbjct: 296 LKKSLAK 302
>Hs14141724 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 499
Score = 142 bits (358), Expect = 1e-33
Identities = 92/282 (32%), Positives = 145/282 (50%), Gaps = 35/282 (12%)
Query: 174 YAVKVINTAKT------RMVKEATILEKLNHPNIIRIHQSCVDALGNVYIFQDLISGGDL 227
YA K+INT K ++ +EA I L HPNI+R+H S + G Y+ DL++GG+L
Sbjct: 40 YAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDS-ISEEGFHYLVFDLVTGGEL 98
Query: 228 FSYLAKGDCLVPISETESLIIIYQILLALKFLHSNGIVHRDLKLDNILLHTPEPCTKVVL 287
F + + SE ++ I QIL ++ H NGIVHRDLK +N+LL + V L
Sbjct: 99 FEDIVAREYY---SEADASHCIQQILESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKL 155
Query: 288 ADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKADRNIYRSFSRTATLDPDNNGYDSKC 347
ADFG+A E+ Q ++ GTP Y +PEV K DP Y
Sbjct: 156 ADFGLAIEV-QGDQQAWFGFAGTPGYLSPEVLRK---------------DP----YGKPV 195
Query: 348 DIWSLGVITHIMLTGISPFYGDGSEASIIKNVRTGKLNFTARQWIAITDSAKSFVKKCLQ 407
D+W+ GVI +I+L G PF+ D + + + ++ G +F + +W +T AK + K L
Sbjct: 196 DMWACGVILYILLVGYPPFW-DEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLT 254
Query: 408 VSTFNRCDVEEALHQVWVEKHTSQLERIYKKKVLQLSSDCIK 449
++ R EAL W+ + ++ +++++ + DC+K
Sbjct: 255 INPAKRITASEALKHPWICQRSTVASMMHRQETV----DCLK 292
>CE28251 [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 469
Score = 142 bits (358), Expect = 1e-33
Identities = 102/358 (28%), Positives = 171/358 (47%), Gaps = 36/358 (10%)
Query: 74 YIKDMSLNGTMVNEQVLSRDVPYLLSNQDVIQL--PNGAKFKFSAVKSETMSQFMTGLRI 131
Y+ D S NGT+VN +++ + + L N D+I + P F + + +T
Sbjct: 110 YLHDHSRNGTLVNHEMIGKGLSRELMNGDLISIAIPALIIFVYERADDNHHPEELT---- 165
Query: 132 KSEWDRWKIVPRIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINT-AKTRMVK-E 189
+++ + ++G G FG VL+ K + + ++ + AKTR ++ E
Sbjct: 166 ----NKYHVTSHLLGKGGFGKVLLGYKKSDRSVVAIKQLNTQFSTRCSRAIAKTRDIQNE 221
Query: 190 ATILEKLNHPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDC-LVPISETESLII 248
+++KL+HPNI+ I+ C+ Y+ + + GG+ FS L + + E+
Sbjct: 222 VEVMKKLSHPNIVAIYD-CITVAKYSYMVIEYVGGGEFFSKLVDSKYNQMGLGESLGKYF 280
Query: 249 IYQILLALKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVV 308
+Q++ A+ +LHS GI HRD+K +NIL + L DFG+AK N+ RM T
Sbjct: 281 AFQLIDAVLYLHSVGICHRDIKPENILCSNKAERCILKLTDFGMAK----NSVNRMKTHC 336
Query: 309 GTPEYCAPEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYG 368
GTP YCAPE+ A++ + Y K DIWSLG + I +G PF
Sbjct: 337 GTPSYCAPEI--VANQGV---------------EYTPKVDIWSLGCVLFITFSGYPPFSE 379
Query: 369 DGSEASIIKNVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVE 426
+ ++ + + V TG+L F QW ITD ++ ++ L V R E + W++
Sbjct: 380 EYTDLKMDEQVLTGRL-FFHEQWHRITDETQNMIQWMLTVEPLIRPSAVELMSTQWMK 436
>7304358 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 493
Score = 142 bits (358), Expect = 1e-33
Identities = 97/294 (32%), Positives = 147/294 (49%), Gaps = 36/294 (12%)
Query: 163 MKRQVAKKT-VSYAVKVINTAKT------RMVKEATILEKLNHPNIIRIHQSCVDALGNV 215
+KR V K T +A K+INT K ++ +EA I KL+HPNI+R+H S + +
Sbjct: 28 VKRCVQKSTGFEFAAKIINTKKLTARDFQKLEREARICRKLHHPNIVRLHDSIQEENYHY 87
Query: 216 YIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHSNGIVHRDLKLDNIL 275
+F DL++GG+LF + + SE ++ I QIL ++ H NG+VHRDLK +N+L
Sbjct: 88 LVF-DLVTGGELFEDIVAREFY---SEADASHCIQQILESVNHCHQNGVVHRDLKPENLL 143
Query: 276 LHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKADRNIYRSFSRTAT 335
L + V LADFG+A E+ Q + GTP Y +PEV K
Sbjct: 144 LASKAKGAAVKLADFGLAIEV-QGDHQAWFGFAGTPGYLSPEVLKK-------------- 188
Query: 336 LDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVRTGKLNFTARQWIAIT 395
Y DIW+ GVI +I+L G PF+ D + + ++ G ++ + +W +T
Sbjct: 189 -----EPYGKSVDIWACGVILYILLVGYPPFW-DEDQHRLYSQIKAGAYDYPSPEWDTVT 242
Query: 396 DSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKHTSQLERIYKKKVLQLSSDCIK 449
AK+ + + L V+ R EAL W+ Q ER+ Q + DC+K
Sbjct: 243 PEAKNLINQMLTVNPNKRITAAEALKHPWI----CQRERVASVVHRQETVDCLK 292
>YPL153c [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 821
Score = 141 bits (355), Expect = 3e-33
Identities = 142/499 (28%), Positives = 224/499 (44%), Gaps = 78/499 (15%)
Query: 31 INKVLKLGRNTEECIYSVEHPS-VSNIHC-VLWGIRFDPESVPLCYIKDMSLNGTMVNEQ 88
I KV GRN C Y + + S +SN H +L G E L + D+S NGT +N Q
Sbjct: 62 IKKVWTFGRNPA-CDYHLGNISRLSNKHFQILLG-----EDGNLL-LNDISTNGTWLNGQ 114
Query: 89 VLSRDVPYLLSNQDVIQLPNGA-------------KFKFSAVKSETMSQFMTGLRIKSE- 134
+ ++ LLS D I + G KFK ++ + + + L+ S+
Sbjct: 115 KVEKNSNQLLSQGDEITVGVGVESDILSLVIFINDKFK-QCLEQNKVDRIRSNLKNTSKI 173
Query: 135 --------------------WDRWKIVPRIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSY 174
+ + I+ +VG G F V A ++R K ++
Sbjct: 174 ASPGLTSSTASSMVANKTGIFKDFSIIDEVVGQGAFATVKKA------IERTTGK---TF 224
Query: 175 AVKVINTAKT-----RMVKEATILEKLNHPNIIRIHQSCVDALGNVYIFQDLISGGDLFS 229
AVK+I+ K + +E +L+KLNHP I+R+ D + Y+ + +SGGDL
Sbjct: 225 AVKIISKRKVIGNMDGVTRELEVLQKLNHPRIVRLKGFYEDT-ESYYMVMEFVSGGDLMD 283
Query: 230 YLAKGDCLVPISETESLIIIYQILLALKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLAD 289
++A + E I QIL A+K++HS GI HRDLK DNIL+ +P V + D
Sbjct: 284 FVAAHGA---VGEDAGREISRQILTAIKYIHSMGISHRDLKPDNILIEQDDP-VLVKITD 339
Query: 290 FGIAKELSQNTKERMHTVVGTPEYCAPEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDI 349
FG+AK Q M T GT Y APEV D ++ + + N Y S D+
Sbjct: 340 FGLAK--VQGNGSFMKTFCGTLAYVAPEVIRGKDTSV------SPDEYEERNEYSSLVDM 391
Query: 350 WSLGVITHIMLTGISPFYGDGSEASIIKNVRTGKLNFTARQWIAITDSAKSFVKKCLQVS 409
WS+G + +++LTG PF G ++ + K + G + + I++ A+ F+ LQV
Sbjct: 392 WSMGCLVYVILTGHLPFSG-STQDQLYKQIGRGSYHEGPLKDFRISEEARDFIDSLLQVD 450
Query: 410 TFNRCDVEEALHQVWVEKHT--SQLERIYKKKVLQLSSDCIKIDENID----TFAVVKHK 463
NR +AL+ W++ SQ + + L S K+ EN+D F + K
Sbjct: 451 PNNRSTAAKALNHPWIKMSPLGSQSYGDFSQISLSQSLSQQKLLENMDDAQYEFVKAQRK 510
Query: 464 LPKSVKLSPEKNPNKRLKL 482
L +L + ++ K+
Sbjct: 511 LQMEQQLQEQDQEDQDGKI 529
>SPCC18B5.11c [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 460
Score = 140 bits (354), Expect = 3e-33
Identities = 122/410 (29%), Positives = 192/410 (46%), Gaps = 51/410 (12%)
Query: 32 NKVLKLGRNTEECIYSVEHPSVSNIHCVLW-GIRFDP-ESVPLCYIKDMSLNGTMVNEQV 89
N + GR+ + C + P VSN H ++ G R D ES + ++ D S NGT +N +
Sbjct: 57 NGFWRFGRH-KSCEVVLNGPRVSNFHFEIYQGHRNDSDESENVVFLHDHSSNGTFLNFER 115
Query: 90 LSRDVPYLLSNQDVIQLPNGA---KFKFSAVKSETMSQFMTGLRIKSEWDRWKIVPRIVG 146
L+++ +LSN D I++ G + F S+ IKSE ++I+ R +G
Sbjct: 116 LAKNSRTILSNGDEIRIGLGVPKDEISFLCQVPVKHSRDSQKNMIKSENSHYEII-RTLG 174
Query: 147 SGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMV-----------KEATILEK 195
SGTF V +A +V+ YA+K+IN K + +E IL+
Sbjct: 175 SGTFAVVKLAVEVNSGKW---------YAIKIINKRKILLTSSEKRATEMFQREIDILKS 225
Query: 196 LNHPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYL-AKGDCLVPISETESLIIIYQILL 254
L+HP +++ H+ + ++I + + GGDL +L A G I E + ++ Q+L
Sbjct: 226 LHHPGVVQCHE-IFENDDELFIVMEYVEGGDLMDFLIANGS----IDEQDCKPLLKQLLE 280
Query: 255 ALKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYC 314
L LH G+ HRD+K +NIL+ + ++DFG+AK + T + T GT Y
Sbjct: 281 TLLHLHKQGVTHRDIKPENILITND---FHLKISDFGLAKVI-HGTGTFLETFCGTMGYL 336
Query: 315 APEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEAS 374
APEV S+ LD GYD K DIWSLG + ++MLT PF S+A
Sbjct: 337 APEV----------LKSKNVNLD---GGYDDKVDIWSLGCVLYVMLTASIPF-ASSSQAK 382
Query: 375 IIKNVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVW 424
I+ + G I++ + + L+++ R EAL W
Sbjct: 383 CIELISKGAYPIEPLLENEISEEGIDLINRMLEINPEKRISESEALQHPW 432
>SPACUNK12.02c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 335
Score = 140 bits (352), Expect = 6e-33
Identities = 93/288 (32%), Positives = 150/288 (51%), Gaps = 42/288 (14%)
Query: 141 VPRIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTA----KTRMVK-EATILEK 195
V R++G GT+ V A ++ N YA K++N K VK E IL++
Sbjct: 33 VGRVLGGGTYATVREAVHIETNKM---------YAAKIMNKKMMEKKQDFVKNEIAILKR 83
Query: 196 LN--HPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYL-AKGDCLVPISETESLIIIYQI 252
++ HPNI+ + + + N+Y+ +L +GG+LF + AKG E ++ ++
Sbjct: 84 VSYEHPNILHL-VDFFETVNNLYLITELATGGELFDRICAKGS----FYEADAAALMRTT 138
Query: 253 LLALKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPE 312
A+K+LH NGIVHRDLK +N+L + +P + +++ADFG++ + + T GTPE
Sbjct: 139 TSAVKYLHDNGIVHRDLKPENLLYRSKDPNSDLLIADFGLSHFYEDSQYYMLMTACGTPE 198
Query: 313 YCAPEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSE 372
Y APEV F RT GY D+W++GVIT+ +L+G +PF S+
Sbjct: 199 YMAPEV-----------FRRT--------GYGKPVDMWAIGVITYFLLSGYTPF-ARPSQ 238
Query: 373 ASIIKNVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEAL 420
+I+ + + F W I+++AK F+KKCL+ R +AL
Sbjct: 239 VEVIEAILANEYTFNDPCWSGISETAKDFIKKCLENDPSKRLTAADAL 286
>Hs7706286 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 489
Score = 139 bits (351), Expect = 7e-33
Identities = 90/282 (31%), Positives = 144/282 (50%), Gaps = 35/282 (12%)
Query: 174 YAVKVINTAKT------RMVKEATILEKLNHPNIIRIHQSCVDALGNVYIFQDLISGGDL 227
YA K+INT K ++ +EA I L HPNI+R+H S + G+ Y+ DL++GG+L
Sbjct: 39 YAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDS-ISEEGHHYLIFDLVTGGEL 97
Query: 228 FSYLAKGDCLVPISETESLIIIYQILLALKFLHSNGIVHRDLKLDNILLHTPEPCTKVVL 287
F + + SE ++ I QIL A+ H G+VHRDLK +N+LL + V L
Sbjct: 98 FEDIVAREYY---SEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKL 154
Query: 288 ADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKADRNIYRSFSRTATLDPDNNGYDSKC 347
ADFG+A E+ + ++ GTP Y +PEV K DP Y
Sbjct: 155 ADFGLAIEV-EGEQQAWFGFAGTPGYLSPEVLRK---------------DP----YGKPV 194
Query: 348 DIWSLGVITHIMLTGISPFYGDGSEASIIKNVRTGKLNFTARQWIAITDSAKSFVKKCLQ 407
D+W+ GVI +I+L G PF+ D + + + ++ G +F + +W +T AK + K L
Sbjct: 195 DLWACGVILYILLVGYPPFW-DEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLT 253
Query: 408 VSTFNRCDVEEALHQVWVEKHTSQLERIYKKKVLQLSSDCIK 449
++ R EAL W+ ++ +++++ + DC+K
Sbjct: 254 INPSKRITAAEALKHPWISHRSTVASCMHRQETV----DCLK 291
>Hs22043888 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 765
Score = 139 bits (349), Expect = 1e-32
Identities = 89/309 (28%), Positives = 149/309 (47%), Gaps = 47/309 (15%)
Query: 141 VPRIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAV----------------KVINTAKT 184
+ +++G G F +V E +D + ++ A K + A ++ + +
Sbjct: 200 IGKVIGDGNFA--VVKECIDRSTGKEFALKIIDKAKCCGKQCAPSNTDTSCEAIVGSTEH 257
Query: 185 RMVKEATILEKLNHPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETE 244
+ E +IL ++ HPNII + + ++ +++ +L+ GGDLF + +E +
Sbjct: 258 LIENEVSILRRVKHPNIIMLVEE-METATELFLVMELVKGGDLFDAITSS---TKYTERD 313
Query: 245 SLIIIYQILLALKFLHSNGIVHRDLKLDNILL-HTPEPCTKVVLADFGIAKELSQNTKER 303
++Y + AL++LH IVHRD+K +N+L+ P+ + L DFG+A + +
Sbjct: 314 GSAMVYNLANALRYLHGLSIVHRDIKPENLLVCEYPDGTKSLKLGDFGLATVV----EGP 369
Query: 304 MHTVVGTPEYCAPEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGI 363
++TV GTP Y APE+ + GY K DIW+ GVIT+I+L G
Sbjct: 370 LYTVCGTPTYVAPEIIAET-------------------GYGLKVDIWAAGVITYILLCGF 410
Query: 364 SPFYGDGS-EASIIKNVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQ 422
PF + + + + + GKL F A W ITDSAK + + LQV+ RC + L
Sbjct: 411 PPFRSENNLQEDLFDQILAGKLEFPAPYWDNITDSAKELISQMLQVNVEARCTAGQILSH 470
Query: 423 VWVEKHTSQ 431
WV SQ
Sbjct: 471 PWVSDDASQ 479
>Hs4758128_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 385
Score = 137 bits (344), Expect = 5e-32
Identities = 92/297 (30%), Positives = 153/297 (50%), Gaps = 44/297 (14%)
Query: 136 DRWKIVPRIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTR-----MVKEA 190
+R+K V R +G G F +V E V+ + R+ YA+K+I +K R + E
Sbjct: 44 ERYK-VGRTIGDGNFA--VVKECVERSTARE-------YALKIIKKSKCRGKEHMIQNEV 93
Query: 191 TILEKLNHPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIY 250
+IL ++ HPNI+ + + +D +Y+ +L+ GGDLF + + +E ++ ++Y
Sbjct: 94 SILRRVKHPNIVLLIEE-MDVPTELYLVMELVKGGDLFDAITSTN---KYTERDASGMLY 149
Query: 251 QILLALKFLHSNGIVHRDLKLDNILLHTPEPCTKVV-LADFGIAKELSQNTKERMHTVVG 309
+ A+K+LHS IVHRD+K +N+L++ + +K + L DFG+A + ++TV G
Sbjct: 150 NLASAIKYLHSLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIVDGP----LYTVCG 205
Query: 310 TPEYCAPEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGD 369
TP Y APE+ + GY K DIW+ GVIT+I+L G PF G
Sbjct: 206 TPTYVAPEIIAET-------------------GYGLKVDIWAAGVITYILLCGFPPFRGS 246
Query: 370 GSEASII-KNVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWV 425
G + ++ + G+++F + W ++DSAK + L V R + L WV
Sbjct: 247 GDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELITMMLLVDVDQRFSAVQVLEHPWV 303
>Hs14776113 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 424
Score = 136 bits (343), Expect = 6e-32
Identities = 87/301 (28%), Positives = 153/301 (49%), Gaps = 43/301 (14%)
Query: 130 RIKSEWDRWKIVPRIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINT----AKTR 185
R+ +++D + ++G G+F V+ +V+H RQ YA+K+I T +
Sbjct: 93 RVTAKYD----IKALIGRGSFSRVV---RVEHRATRQ------PYAIKMIETKYREGREV 139
Query: 186 MVKEATILEKLNHPNIIRIHQSCVDALGNVYIFQDLISGGDLFS-YLAKGDCLVPISETE 244
E +L ++ H NII++ + + VY+ +L +GG+LF +AKG +E +
Sbjct: 140 CESELRVLRRVRHANIIQLVE-VFETQERVYMVMELATGGELFDRIIAKGS----FTERD 194
Query: 245 SLIIIYQILLALKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERM 304
+ ++ +L +++LH+ GI HRDLK +N+L + P +K+++ DFG+A + M
Sbjct: 195 ATRVLQMVLDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASARKKGDDCLM 254
Query: 305 HTVVGTPEYCAPEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGIS 364
T GTPEY APEV + Y + D+W+LGVI +I+L+G
Sbjct: 255 KTTCGTPEYIAPEVLVR-------------------KPYTNSVDMWALGVIAYILLSGTM 295
Query: 365 PFYGDGSEASIIKNVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVW 424
PF D + + + + GK +++ W ++++ AK F+ + L V R +AL W
Sbjct: 296 PF-EDDNRTRLYRQILRGKYSYSGEPWPSVSNLAKDFIDRLLTVDPGARMTALQALRHPW 354
Query: 425 V 425
V
Sbjct: 355 V 355
>7304311 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 405
Score = 136 bits (343), Expect = 6e-32
Identities = 97/355 (27%), Positives = 168/355 (47%), Gaps = 57/355 (16%)
Query: 144 IVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILE--------- 194
++G+G F V +AE D + +AVK+I+ + +E+ E
Sbjct: 36 LLGTGAFSEVRLAESKDSPGEH--------FAVKIIDKKALKGKEESLENEIRVLRRFSA 87
Query: 195 -----------KLNHPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLA-KGDCLVPISE 242
+L HPNI+++ ++ D VY+ +L++GG+LF + KG +E
Sbjct: 88 NHFDGKCLNGTRLTHPNIVQLLETYEDK-SKVYLVMELVTGGELFDRIVEKGS----YTE 142
Query: 243 TESLIIIYQILLALKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKE 302
++ +I QIL A+ ++H G+VHRDLK +N+L ++P+ +K++++DFG++K
Sbjct: 143 KDASHLIRQILEAVDYMHEQGVVHRDLKPENLLYYSPDDDSKIMISDFGLSK---MEDSG 199
Query: 303 RMHTVVGTPEYCAPEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTG 362
M T GTP Y APEV Y D+WS+GVI++I+L G
Sbjct: 200 IMATACGTPGYVAPEV-------------------LAQKPYGKAVDVWSIGVISYILLCG 240
Query: 363 ISPFYGDGSEASIIKNVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQ 422
PFY D ++A++ + G F + W I++SAK F+K + V+ R ++AL
Sbjct: 241 YPPFY-DENDANLFAQILKGDFEFDSPYWDEISESAKHFIKNLMCVTVEKRYTCKQALGH 299
Query: 423 VWVEKHTSQLERIYKKKVLQLSSDCIKIDENIDTFAVVKHKLPKSVKLSPEKNPN 477
W+ + + I+ QL + K +A + + + L+ N N
Sbjct: 300 AWISGNEASSRNIHGTVSEQLKKNFAKSRWKQAYYAATVIRQMQRMALNSNSNAN 354
>CE27297 [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 476
Score = 135 bits (340), Expect = 1e-31
Identities = 101/358 (28%), Positives = 172/358 (47%), Gaps = 36/358 (10%)
Query: 74 YIKDMSLNGTMVNEQVLSRDVPYLLSNQDVIQL--PNGAKFKFSAVKSETMSQFMTGLRI 131
Y+ D S NGT+VN++++ + + L N D+I + P F + + ++ + +T
Sbjct: 111 YLHDHSRNGTLVNQEMIGKGLSRELMNGDLISIGIPALIIFVYESADADHHPEELT---- 166
Query: 132 KSEWDRWKIVPRIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINT-AKTRMVK-E 189
++ + +G G FG VL+ K + + ++ + AKTR ++ E
Sbjct: 167 ----KKYHVTSHSLGKGGFGKVLLGYKKSDRSVVAIKQLNTQFSTRCSRAIAKTRDIRNE 222
Query: 190 ATILEKLNHPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDC-LVPISETESLII 248
+++KL+HPNI+ I+ A + Y+ + + GG+ FS + + + E+
Sbjct: 223 VEVMKKLSHPNIVAIYDWITVAKYS-YMVIEYVGGGEFFSKVVDSKYNRMGLGESLGKYF 281
Query: 249 IYQILLALKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVV 308
+Q++ A+ +LHS GI HRD+K +NIL + L DFG+AK N+ RM T
Sbjct: 282 AFQLIDAILYLHSVGICHRDIKPENILCSDKAERCILKLTDFGMAK----NSVNRMKTRC 337
Query: 309 GTPEYCAPEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYG 368
GTP Y APE+ + + Y K DIWSLG + I +G PF
Sbjct: 338 GTPSYNAPEI-----------------VANEGVEYTPKVDIWSLGCVLFITFSGYPPFSE 380
Query: 369 DGSEASIIKNVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVE 426
+ ++ ++ + V TG+L F A QW IT ++ +K L V NR E + W++
Sbjct: 381 EYTDMTMDEQVLTGRLIFHA-QWRRITVETQNMIKWMLTVEPSNRPSAVELMSTQWMK 437
>Hs9966875 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 357
Score = 135 bits (339), Expect = 2e-31
Identities = 88/320 (27%), Positives = 161/320 (49%), Gaps = 32/320 (10%)
Query: 145 VGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKLNHPNIIRI 204
+G+G F V++AE + + A K + K + ++ + E +L K+ H NI+ +
Sbjct: 29 LGTGAFSEVVLAE--EKATGKLFAVKCIPK--KALKGKESSIENEIAVLRKIKHENIVAL 84
Query: 205 HQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHSNGI 264
+ ++ ++Y+ L+SGG+LF + + +E ++ +I Q+L A+ +LH GI
Sbjct: 85 -EDIYESPNHLYLVMQLVSGGELFDRIVEKGFY---TEKDASTLIRQVLDAVYYLHRMGI 140
Query: 265 VHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKADR 324
VHRDLK +N+L ++ + +K++++DFG++K + + M T GTP Y APEV
Sbjct: 141 VHRDLKPENLLYYSQDEESKIMISDFGLSK--MEGKGDVMSTACGTPGYVAPEV------ 192
Query: 325 NIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVRTGKL 384
Y D WS+GVI +I+L G PFY D +++ + + + +
Sbjct: 193 -------------LAQKPYSKAVDCWSIGVIAYILLCGYPPFY-DENDSKLFEQILKAEY 238
Query: 385 NFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKHTSQLERIYKKKVLQLS 444
F + W I+DSAK F++ ++ R E+A W+ T+ + I++ Q+
Sbjct: 239 EFDSPYWDDISDSAKDFIRNLMEKDPNKRYTCEQAARHPWIAGDTALNKNIHESVSAQIR 298
Query: 445 SDCIKID--ENIDTFAVVKH 462
+ K + + AVV+H
Sbjct: 299 KNFAKSKWRQAFNATAVVRH 318
>Hs20127418 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 664
Score = 134 bits (336), Expect = 4e-31
Identities = 88/282 (31%), Positives = 142/282 (50%), Gaps = 35/282 (12%)
Query: 174 YAVKVINTAKT------RMVKEATILEKLNHPNIIRIHQSCVDALGNVYIFQDLISGGDL 227
YA K+INT K ++ +EA I L H NI+R+H S + G Y+ DL++GG+L
Sbjct: 40 YAAKIINTKKLSARDHQKLEREARICRLLKHSNIVRLHDS-ISEEGFHYLVFDLVTGGEL 98
Query: 228 FSYLAKGDCLVPISETESLIIIYQILLALKFLHSNGIVHRDLKLDNILLHTPEPCTKVVL 287
F + + SE ++ I QIL A+ H G+VHRDLK +N+LL + V L
Sbjct: 99 FEDIVAREYY---SEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKL 155
Query: 288 ADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKADRNIYRSFSRTATLDPDNNGYDSKC 347
ADFG+A E+ Q ++ GTP Y +PEV K Y
Sbjct: 156 ADFGLAIEV-QGDQQAWFGFAGTPGYLSPEVLRK-------------------EAYGKPV 195
Query: 348 DIWSLGVITHIMLTGISPFYGDGSEASIIKNVRTGKLNFTARQWIAITDSAKSFVKKCLQ 407
DIW+ GVI +I+L G PF+ D + + + ++ G +F + +W +T AK+ + + L
Sbjct: 196 DIWACGVILYILLVGYPPFW-DEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLT 254
Query: 408 VSTFNRCDVEEALHQVWVEKHTSQLERIYKKKVLQLSSDCIK 449
++ R EAL WV + ++ +++++ + +C+K
Sbjct: 255 INPAKRITAHEALKHPWVCQRSTVASMMHRQETV----ECLK 292
>Hs14916455 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 385
Score = 132 bits (332), Expect = 1e-30
Identities = 89/315 (28%), Positives = 160/315 (50%), Gaps = 44/315 (13%)
Query: 141 VPRIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINT----AKTRMVKEATILEKL 196
+ ++G+G+F V+ E+ + KK +A+KV+ T + V E ++L ++
Sbjct: 65 IKALIGTGSFSRVVRVEQ-------KTTKKP--FAIKVMETREREGREACVSELSVLRRV 115
Query: 197 NHPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYL-AKGDCLVPISETESLIIIYQILLA 255
+H I+++ + + VY+ +L +GG+LF L A+G +E +++ I+ +
Sbjct: 116 SHRYIVQLME-IFETEDQVYMVMELATGGELFDRLIAQGS----FTERDAVRILQMVADG 170
Query: 256 LKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCA 315
+++LH+ I HR+LK +N+L + P +K+++ DFG+A ++ M T+ GTPEY A
Sbjct: 171 IRYLHALQITHRNLKPENLLYYHPGEESKILITDFGLAYSGKKSGDWTMKTLCGTPEYIA 230
Query: 316 PEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASI 375
PEV + Y S D+W+LGVIT+ +L+G PF D S+ +
Sbjct: 231 PEVLLR-------------------KPYTSAVDMWALGVITYALLSGFLPF-DDESQTRL 270
Query: 376 IKNVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWV-----EKHTS 430
+ + GK N+T W +I+ AK F+ K L + +R +AL WV
Sbjct: 271 YRKILKGKYNYTGEPWPSISHLAKDFIDKLLILEAGHRMSAGQALDHPWVITMAAGSSMK 330
Query: 431 QLERIYKKKVLQLSS 445
L+R + ++Q +S
Sbjct: 331 NLQRAISRNLMQRAS 345
>Hs4502557 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 473
Score = 132 bits (331), Expect = 2e-30
Identities = 83/254 (32%), Positives = 136/254 (52%), Gaps = 27/254 (10%)
Query: 174 YAVKVIN-TAKTRMVK-EATILEKLNHPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYL 231
YA+KV+ T ++V+ E +L +L+HPNII++ + + + + +L++GG+LF +
Sbjct: 72 YALKVLKKTVDKKIVRTEIGVLLRLSHPNIIKLKE-IFETPTEISLVLELVTGGELFDRI 130
Query: 232 AKGDCLVPISETESLIIIYQILLALKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFG 291
+ SE ++ + QIL A+ +LH NGIVHRDLK +N+L TP P + +ADFG
Sbjct: 131 VEKGYY---SERDAADAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPDAPLKIADFG 187
Query: 292 IAKELSQNTKERMHTVVGTPEYCAPEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWS 351
++K + M TV GTP YCAPE I R + Y + D+WS
Sbjct: 188 LSKIVEHQV--LMKTVCGTPGYCAPE--------ILRGCA-----------YGPEVDMWS 226
Query: 352 LGVITHIMLTGISPFYGDGSEASIIKNVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTF 411
+G+IT+I+L G PFY + + + + + + F + W ++ +AK V+K + +
Sbjct: 227 VGIITYILLCGFEPFYDERGDQFMFRRILNCEYYFISPWWDEVSLNAKDLVRKLIVLDPK 286
Query: 412 NRCDVEEALHQVWV 425
R +AL WV
Sbjct: 287 KRLTTFQALQHPWV 300
>CE09360 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 2783
Score = 131 bits (329), Expect = 3e-30
Identities = 86/309 (27%), Positives = 159/309 (50%), Gaps = 39/309 (12%)
Query: 130 RIKSEWDRWKIVPRIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTA----KTR 185
R+ ++ I+ +G G +G V A + + KT +A K++ K
Sbjct: 186 RLPNDLQAKYIIHEELGKGAYGTVYRATE-------KATGKT--WAAKMVQVRPGVKKEN 236
Query: 186 MVKEATILEKLNHPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETES 245
++ E +++ +L+H ++ +H++ D +++ ++ +SGG+LF + + D L+ SE E
Sbjct: 237 VIHEISMMNQLHHEKLLNLHEA-FDMGNEMWLIEEFVSGGELFEKILEDDSLM--SEEEV 293
Query: 246 LIIIYQILLALKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMH 305
++QILL + +H N IVH DLK +NILL ++ + DFG+A++L + K+ +
Sbjct: 294 RDYMHQILLGVSHMHKNQIVHLDLKPENILLKAKNS-NELKIIDFGLARKL--DPKKSVK 350
Query: 306 TVVGTPEYCAPEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISP 365
+ GTPE+CAPEV + D+W++GVI++++L+G+SP
Sbjct: 351 LLFGTPEFCAPEV-------------------VNYQPVGLSTDMWTVGVISYVLLSGLSP 391
Query: 366 FYGDGSEASIIKNVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWV 425
F GD S+ + NV +F W ++D AK F+ + + R V++AL W+
Sbjct: 392 FLGD-SDEDTLANVSASDWDFDDPSWDDVSDLAKDFICRLMIKDKRKRMSVQDALRHPWI 450
Query: 426 EKHTSQLER 434
K +L++
Sbjct: 451 TKMQPKLDK 459
>Hs20479818 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 514
Score = 130 bits (328), Expect = 3e-30
Identities = 95/323 (29%), Positives = 157/323 (48%), Gaps = 43/323 (13%)
Query: 143 RIVGSGTFGHVLVAEKVDHNMKRQVAK----KTVSYAVKVINTAKTRMVKEATILEKLNH 198
RI+G G+FG V+ A + K + K K S AVK++ +E IL+ + H
Sbjct: 120 RILGKGSFGIVIEATDKETETKWAIKKVNKEKAGSSAVKLLE-------REVNILKSVKH 172
Query: 199 PNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKF 258
+II + Q + +Y+ +L G+L L D SE E+ II + A+ +
Sbjct: 173 EHIIHLEQ-VFETPKKMYLVMELCEDGELKEIL---DRKGHFSENETRWIIQSLASAIAY 228
Query: 259 LHSNGIVHRDLKLDNILLHTP------EPCTKVVLADFGIAKELSQNTKERMHTVVGTPE 312
LH+N IVHRDLKL+NI++ + E + + DFG+A + ++ + GTP
Sbjct: 229 LHNNDIVHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQATCGTPI 288
Query: 313 YCAPEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSE 372
Y APEV D Y +CDIWS+GV+ +++L G PF SE
Sbjct: 289 YMAPEVISAHD-------------------YSQQCDIWSIGVVMYMLLRGEPPFLA-SSE 328
Query: 373 ASIIKNVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKHTSQL 432
+ + +R G+L+F W +I+D AKS +K+ ++V +R +E L W+ ++L
Sbjct: 329 EKLFELIRKGELHFENAVWNSISDCAKSVLKQLMKVDPAHRITAKELLDNQWLT--GNKL 386
Query: 433 ERIYKKKVLQLSSDCIKIDENID 455
+ VL++ + E+++
Sbjct: 387 SSVRPTNVLEMMKEWKNNPESVE 409
>YOL016c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 447
Score = 130 bits (326), Expect = 6e-30
Identities = 90/288 (31%), Positives = 148/288 (51%), Gaps = 28/288 (9%)
Query: 140 IVPRIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKLNHP 199
I R +G+G+FG V A K+ N + K + A++ N + +E +IL+KL+HP
Sbjct: 48 IFGRTLGAGSFGVVRQARKLSTNEDVAI-KILLKKALQGNNVQLQMLYEELSILQKLSHP 106
Query: 200 NIIRIHQSCVDALGNVYIFQDLISGGDLFS-YLAKGDCLVPISETESLIIIYQILLALKF 258
NI+ + ++ YI L +GG+LF L++G +E +++ II QIL A+++
Sbjct: 107 NIVSF-KDWFESKDKFYIVTQLATGGELFDRILSRGK----FTEVDAVEIIVQILGAVEY 161
Query: 259 LHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEV 318
+HS +VHRDLK +N+L + +V+ADFGIAK+L + ++ ++ G+ Y APEV
Sbjct: 162 MHSKNVVHRDLKPENVLYVDKSENSPLVIADFGIAKQL-KGEEDLIYKAAGSLGYVAPEV 220
Query: 319 GFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIK- 377
+G+ CDIWS+GVIT+ +L G SPF + E + +
Sbjct: 221 -------------------LTQDGHGKPCDIWSIGVITYTLLCGYSPFIAESVEGFMEEC 261
Query: 378 NVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWV 425
+ F W I+ K F+ K L+++ +R E L W+
Sbjct: 262 TASRYPVTFHMPYWDNISIDVKRFILKALRLNPADRPTATELLDDPWI 309
>At1g12580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 522
Score = 129 bits (325), Expect = 8e-30
Identities = 89/284 (31%), Positives = 140/284 (48%), Gaps = 30/284 (10%)
Query: 145 VGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKL-NHPNIIR 203
+G G FG + V D ++A K++S V + E I+ KL HPN++
Sbjct: 50 LGWGQFGVIRVCS--DKLTGERLACKSISKDRLVTQDDMKSIKLEIAIMAKLAGHPNVVN 107
Query: 204 IHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHSNG 263
+ ++ + +V++ +L +GG+LF L K SE + ++ ++ +KF H +G
Sbjct: 108 L-KAVYEEKDSVHLVMELCAGGELFHKLEKYG---RYSEVRARVLFKHLMQVVKFCHDSG 163
Query: 264 IVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKAD 323
IVHRDLK +NIL+ T + + LADFG+A + E++ VG+P Y APEV
Sbjct: 164 IVHRDLKPENILMATMSSSSPIKLADFGLATYIKPG--EKLSGTVGSPFYIAPEV----- 216
Query: 324 RNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVRTGK 383
GY+ D+WS GVI +I+L+G PF+G +++ I VR
Sbjct: 217 ---------------LAGGYNQAADVWSAGVILYILLSGAPPFWGK-TKSKIFDAVRAAD 260
Query: 384 LNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEK 427
L F+A W IT AK ++ L V R +E L W+E+
Sbjct: 261 LRFSAEPWDNITSYAKDLIRGMLCVDPSQRLSADEVLAHSWMEQ 304
>YDL101c [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 513
Score = 129 bits (323), Expect = 1e-29
Identities = 122/485 (25%), Positives = 201/485 (41%), Gaps = 94/485 (19%)
Query: 28 QIEINKVLKLGRNTEECIYSVEHPSVSNIHCVLWGIRFDPESVP--LCYIKDMSLNGTMV 85
+I V +GR+ C + P +S H ++ D ++ L + D S NGT +
Sbjct: 49 EITNRNVTTIGRS-RSCDVILSEPDISTFHAEFHLLQMDVDNFQRNLINVIDKSRNGTFI 107
Query: 86 N-EQVLSRDVPYLLSNQDVIQLPNGAKFKFSAVKSETMSQFMTGLRIKSEWDRWK----- 139
N +++ +D Y+L N D I F F S + ++ SE +K
Sbjct: 108 NGNRLVKKD--YILKNGDRIVFGKSCSFLFKYASSSSTDIENDDEKVSSESRSYKNDDEV 165
Query: 140 -----------------------------------IVPRIVGSGTFGHVLVAEKVDHNMK 164
++ + +G+G + LV E +
Sbjct: 166 FKKPQISATSSQNATTSAAIRKLNKTRPVSFFDKYLLGKELGAGHYA--LVKEAKNKKTG 223
Query: 165 RQVAKKTVSYAVKVINTAKTRMVKEAT-ILEKLNHPNIIRIHQSCVDALGNV----YIFQ 219
+QVA K + +A + + K + +E T IL ++ HPNI+ + S V+ + Y+
Sbjct: 224 QQVAVK-IFHAQQNDDQKKNKQFREETNILMRVQHPNIVNLLDSFVEPISKSQIQKYLVL 282
Query: 220 DLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHSNGIVHRDLKLDNILLHTP 279
+ I G+LF + + CL + ES + Q+L LK+LH I+HRD+K +NILL+
Sbjct: 283 EKIDDGELFERIVRKTCL---RQDESKALFKQLLTGLKYLHEQNIIHRDIKPENILLNIT 339
Query: 280 ----------------EPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKAD 323
E +V +ADFG+AK + + +T+ GTP Y APEV K
Sbjct: 340 RRENPSQVQLGPWDEDEIDIQVKIADFGLAKFTGE--MQFTNTLCGTPSYVAPEVLTK-- 395
Query: 324 RNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVRTGK 383
GY SK D+WS GVI ++ L G PF S+ + + K
Sbjct: 396 -----------------KGYTSKVDLWSAGVILYVCLCGFPPFSDQLGPPSLKEQILQAK 438
Query: 384 LNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKHTSQLERIYKKKVLQL 443
F + W I DS + L ++ R +++EAL+ W Q + + LQ+
Sbjct: 439 YAFYSPYWDKIDDSVLHLISNLLVLNPDERYNIDEALNHPWFNDIQQQSSVSLELQRLQI 498
Query: 444 SSDCI 448
+ + I
Sbjct: 499 TDNKI 503
>Hs14728804 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 576
Score = 128 bits (322), Expect = 2e-29
Identities = 88/311 (28%), Positives = 150/311 (47%), Gaps = 44/311 (14%)
Query: 143 RIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTR-----MVKEATILEKLN 197
R++G G F V ++ H RQ +YA+K+I+ ++ + + E I++ L+
Sbjct: 288 RVIGDGNFA---VVKECRHRETRQ------AYAMKIIDKSRLKGKEDMVDSEILIIQSLS 338
Query: 198 HPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALK 257
HPNI+++H+ + +Y+ + + GGDLF + + V E ++ ++I + AL
Sbjct: 339 HPNIVKLHEVYETDM-EIYLILEYVQGGDLFDAIIES---VKFPEPDAALMIMDLCKALV 394
Query: 258 FLHSNGIVHRDLKLDNILLHTPE-PCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAP 316
+H IVHRDLK +N+L+ E T + LADFG+AK + + + TV GTP Y AP
Sbjct: 395 HMHDKSIVHRDLKPENLLVQRNEDKSTTLKLADFGLAKHVVR----PIFTVCGTPTYVAP 450
Query: 317 EVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYG-DGSEASI 375
E+ GY + D+W+ GVI +I+L G PF + + +
Sbjct: 451 EI-------------------LSEKGYGLEVDMWAAGVILYILLCGFPPFRSPERDQDEL 491
Query: 376 IKNVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKHTSQLERI 435
++ G F W I+D+AK V + L V R + L W+E + +
Sbjct: 492 FNIIQLGHFEFLPPYWDNISDAAKDLVSRLLVVDPKKRYTAHQVLQHPWIET-AGKTNTV 550
Query: 436 YKKKVLQLSSD 446
++K + SS+
Sbjct: 551 KRQKQVSPSSE 561
>At2g17890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 571
Score = 127 bits (318), Expect = 5e-29
Identities = 93/296 (31%), Positives = 146/296 (48%), Gaps = 30/296 (10%)
Query: 134 EWDRWKIVPRIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATIL 193
++D + +++G G FG+ VA D +VA K + A I A + +E IL
Sbjct: 103 DFDHRYTIGKLLGHGQFGYTYVA--TDKKTGDRVAVKKIDKAKMTIPIAVEDVKREVKIL 160
Query: 194 EKLN-HPNIIRIHQSCVDALGNVYIFQDLISGGDLFS-YLAKGDCLVPISETESLIIIYQ 251
+ L H N++R + + D +VYI +L GG+L LA+ D SE ++ +++ Q
Sbjct: 161 QALTGHENVVRFYNAFEDK-NSVYIVMELCEGGELLDRILARKDSRY--SERDAAVVVRQ 217
Query: 252 ILLALKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTP 311
+L H G+VHRD+K +N L + E + + DFG++ + K H +VG+
Sbjct: 218 MLKVAAECHLRGLVHRDMKPENFLFKSTEEDSPLKATDFGLSDFIKPGKK--FHDIVGSA 275
Query: 312 EYCAPEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGS 371
Y APEV + +G +S D+WS+GVI++I+L G PF+ D +
Sbjct: 276 YYVAPEVLKR------------------RSGPES--DVWSIGVISYILLCGRRPFW-DKT 314
Query: 372 EASIIKNVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEK 427
E I K V K +F + W I++SAK FVKK L R +AL WV +
Sbjct: 315 EDGIFKEVLKNKPDFRRKPWPTISNSAKDFVKKLLVKDPRARLTAAQALSHPWVRE 370
>Hs16950621 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 992
Score = 125 bits (315), Expect = 1e-28
Identities = 91/294 (30%), Positives = 151/294 (50%), Gaps = 41/294 (13%)
Query: 145 VGSGTFGHV--LVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKLNHPNII 202
+GSG FG V LV +K K K +Y+ K K + +E +I+ L+HP ++
Sbjct: 548 LGSGKFGQVFRLVEKKT---RKVWAGKFFKAYSAK----EKENIRQEISIMNCLHHPKLV 600
Query: 203 RIHQSCVDAL---GNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFL 259
+ CVDA N+ + +++SGG+LF + D ++E E + + QI ++++
Sbjct: 601 Q----CVDAFEEKANIVMVLEIVSGGELFERIIDED--FELTERECIKYMRQISEGVEYI 654
Query: 260 HSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVG 319
H GIVH DLK +NI+ + T++ L DFG+A+ L + + GTPE+ APEV
Sbjct: 655 HKQGIVHLDLKPENIMC-VNKTGTRIKLIDFGLARRLENAGS--LKVLFGTPEFVAPEV- 710
Query: 320 FKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNV 379
++ + GY + D+WS+GVI +I+++G+SPF GD ++ + NV
Sbjct: 711 ----------------INYEPIGYAT--DMWSIGVICYILVSGLSPFMGD-NDNETLANV 751
Query: 380 RTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKHTSQLE 433
+ +F + I+D AK F+ L+ NR D + L W+ K T +E
Sbjct: 752 TSATWDFDDEAFDEISDDAKDFISNLLKKDMKNRLDCTQCLQHPWLMKDTKNME 805
>Hs16950613 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 1845
Score = 125 bits (315), Expect = 1e-28
Identities = 91/294 (30%), Positives = 151/294 (50%), Gaps = 41/294 (13%)
Query: 145 VGSGTFGHV--LVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKLNHPNII 202
+GSG FG V LV +K K K +Y+ K K + +E +I+ L+HP ++
Sbjct: 1401 LGSGKFGQVFRLVEKKT---RKVWAGKFFKAYSAK----EKENIRQEISIMNCLHHPKLV 1453
Query: 203 RIHQSCVDAL---GNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFL 259
+ CVDA N+ + +++SGG+LF + D ++E E + + QI ++++
Sbjct: 1454 Q----CVDAFEEKANIVMVLEIVSGGELFERIIDED--FELTERECIKYMRQISEGVEYI 1507
Query: 260 HSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVG 319
H GIVH DLK +NI+ + T++ L DFG+A+ L + + GTPE+ APEV
Sbjct: 1508 HKQGIVHLDLKPENIMC-VNKTGTRIKLIDFGLARRLENAGS--LKVLFGTPEFVAPEV- 1563
Query: 320 FKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNV 379
++ + GY + D+WS+GVI +I+++G+SPF GD ++ + NV
Sbjct: 1564 ----------------INYEPIGYAT--DMWSIGVICYILVSGLSPFMGD-NDNETLANV 1604
Query: 380 RTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKHTSQLE 433
+ +F + I+D AK F+ L+ NR D + L W+ K T +E
Sbjct: 1605 TSATWDFDDEAFDEISDDAKDFISNLLKKDMKNRLDCTQCLQHPWLMKDTKNME 1658
>Hs16950611 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 1914
Score = 125 bits (315), Expect = 1e-28
Identities = 91/294 (30%), Positives = 151/294 (50%), Gaps = 41/294 (13%)
Query: 145 VGSGTFGHV--LVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKLNHPNII 202
+GSG FG V LV +K K K +Y+ K K + +E +I+ L+HP ++
Sbjct: 1470 LGSGKFGQVFRLVEKKT---RKVWAGKFFKAYSAK----EKENIRQEISIMNCLHHPKLV 1522
Query: 203 RIHQSCVDAL---GNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFL 259
+ CVDA N+ + +++SGG+LF + D ++E E + + QI ++++
Sbjct: 1523 Q----CVDAFEEKANIVMVLEIVSGGELFERIIDED--FELTERECIKYMRQISEGVEYI 1576
Query: 260 HSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVG 319
H GIVH DLK +NI+ + T++ L DFG+A+ L + + GTPE+ APEV
Sbjct: 1577 HKQGIVHLDLKPENIMC-VNKTGTRIKLIDFGLARRLENAGS--LKVLFGTPEFVAPEV- 1632
Query: 320 FKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNV 379
++ + GY + D+WS+GVI +I+++G+SPF GD ++ + NV
Sbjct: 1633 ----------------INYEPIGYAT--DMWSIGVICYILVSGLSPFMGD-NDNETLANV 1673
Query: 380 RTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKHTSQLE 433
+ +F + I+D AK F+ L+ NR D + L W+ K T +E
Sbjct: 1674 TSATWDFDDEAFDEISDDAKDFISNLLKKDMKNRLDCTQCLQHPWLMKDTKNME 1727
>Hs16950601 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 991
Score = 125 bits (315), Expect = 1e-28
Identities = 91/294 (30%), Positives = 151/294 (50%), Gaps = 41/294 (13%)
Query: 145 VGSGTFGHV--LVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKLNHPNII 202
+GSG FG V LV +K K K +Y+ K K + +E +I+ L+HP ++
Sbjct: 548 LGSGKFGQVFRLVEKKT---RKVWAGKFFKAYSAK----EKENIRQEISIMNCLHHPKLV 600
Query: 203 RIHQSCVDAL---GNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFL 259
+ CVDA N+ + +++SGG+LF + D ++E E + + QI ++++
Sbjct: 601 Q----CVDAFEEKANIVMVLEIVSGGELFERIIDED--FELTERECIKYMRQISEGVEYI 654
Query: 260 HSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVG 319
H GIVH DLK +NI+ + T++ L DFG+A+ L + + GTPE+ APEV
Sbjct: 655 HKQGIVHLDLKPENIMC-VNKTGTRIKLIDFGLARRLENAGS--LKVLFGTPEFVAPEV- 710
Query: 320 FKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNV 379
++ + GY + D+WS+GVI +I+++G+SPF GD ++ + NV
Sbjct: 711 ----------------INYEPIGYAT--DMWSIGVICYILVSGLSPFMGD-NDNETLANV 751
Query: 380 RTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKHTSQLE 433
+ +F + I+D AK F+ L+ NR D + L W+ K T +E
Sbjct: 752 TSATWDFDDEAFDEISDDAKDFISNLLKKDMKNRLDCTQCLQHPWLMKDTKNME 805
>Hs14670383 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 370
Score = 125 bits (315), Expect = 1e-28
Identities = 85/285 (29%), Positives = 144/285 (49%), Gaps = 37/285 (12%)
Query: 172 VSYAVKVINTAKTR----------MVKEATILEKLNHPNIIRIHQSCVDALGNVYIFQDL 221
+ YA K I ++R + +E +IL ++ H N+I +H + +V + +L
Sbjct: 47 LEYAAKFIKKRQSRASRRGVSREEIEREVSILRQVLHHNVITLHD-VYENRTDVVLILEL 105
Query: 222 ISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHSNGIVHRDLKLDNILLHTPE- 280
+SGG+LF +LA+ + L SE E+ I QIL + +LH+ I H DLK +NI+L
Sbjct: 106 VSGGELFDFLAQKESL---SEEEATSFIKQILDGVNYLHTKKIAHFDLKPENIMLLDKNI 162
Query: 281 PCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKADRNIYRSFSRTATLDPDN 340
P + L DFG+A E+ + + + GTPE+ APE+ +P
Sbjct: 163 PIPHIKLIDFGLAHEIEDGVEFK--NIFGTPEFVAPEI---------------VNYEP-- 203
Query: 341 NGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVRTGKLNFTARQWIAITDSAKS 400
+ D+WS+GVIT+I+L+G SPF GD ++ + N+ +F + ++ AK
Sbjct: 204 --LGLEADMWSIGVITYILLSGASPFLGD-TKQETLANITAVSYDFDEEFFSQTSELAKD 260
Query: 401 FVKKCLQVSTFNRCDVEEALHQVWVEKHTSQLERIYKKKVLQLSS 445
F++K L T R ++EAL W+ +Q + ++ V+ L +
Sbjct: 261 FIRKLLVKETRKRLTIQEALRHPWITPVDNQQAMVRRESVVNLEN 305
>YFR014c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 446
Score = 125 bits (314), Expect = 1e-28
Identities = 87/285 (30%), Positives = 141/285 (48%), Gaps = 28/285 (9%)
Query: 143 RIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKLNHPNII 202
+ +G+GTFG V A+ + V K + A+K + E IL++L+HPNI+
Sbjct: 41 KTLGAGTFGVVRQAKNTETGEDVAV-KILIKKALKGNKVQLEALYDELDILQRLHHPNIV 99
Query: 203 RIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHSN 262
+ ++ YI L GG+LF + K +E +++ I+ +IL A+K++HS
Sbjct: 100 AF-KDWFESKDKFYIITQLAKGGELFDRILKKG---KFTEEDAVRILVEILSAVKYMHSQ 155
Query: 263 GIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKA 322
IVHRDLK +N+L + +V+ADFGIAK L ++ +E ++ G+ Y APEV
Sbjct: 156 NIVHRDLKPENLLYIDKSDESPLVVADFGIAKRL-KSDEELLYKPAGSLGYVAPEV---- 210
Query: 323 DRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVRTG 382
+G+ CDIWS+GVIT+ +L G S F + + + TG
Sbjct: 211 ---------------LTQDGHGKPCDIWSIGVITYTLLCGYSAFRAERVQ-DFLDECTTG 254
Query: 383 K--LNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWV 425
+ + F W ++++ AK F+ K L + R E L W+
Sbjct: 255 EYPVKFHRPYWDSVSNKAKQFILKALNLDPSKRPTAAELLEDPWI 299
>CE02377 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 1211
Score = 125 bits (314), Expect = 1e-28
Identities = 86/301 (28%), Positives = 151/301 (49%), Gaps = 33/301 (10%)
Query: 129 LRIKSEWDRWKIVPRIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTA-KTRMV 187
+R ++D V +++G G FG V ++++ K+ + +K+ A + +
Sbjct: 35 IRANVKFDTLYQVTKLLGDGKFGKVYCV------IEKETGKEFAAKFIKIRKEADRAEVE 88
Query: 188 KEATILEKLNHPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLI 247
+E +IL +L HP I +I+ + +V + +++ GG+LF +A+ + +SE ++
Sbjct: 89 REVSILTQLRHPRIAQIYDAFYTTTNDVVLIMEIVRGGELFDRVAEESYV--LSELAVVM 146
Query: 248 IIYQILLALKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTV 307
II Q+ A+ ++H I+H D+K +NI+ + ++ L DFG+A+ + + +
Sbjct: 147 IICQLCEAIDYIHKQNILHLDVKPENIMCVSLTG-NRIKLIDFGLARHYDGT--QELKYM 203
Query: 308 VGTPEYCAPEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFY 367
GTPE+ APEV K ++ Y + D+WS+GVIT+I+L+G SPF
Sbjct: 204 AGTPEFAAPEV-IKFEKLDYHT------------------DMWSIGVITYILLSGYSPFL 244
Query: 368 GDGSEASIIKNVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEK 427
GD + NV G FT ++ +T+ AK FV K L R E L W+ K
Sbjct: 245 GDNLGETYC-NVEKGVWEFT-EEFDTVTEEAKDFVTKLLVYDQSKRMLPHECLQHPWIAK 302
Query: 428 H 428
H
Sbjct: 303 H 303
>At5g24430 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 594
Score = 124 bits (311), Expect = 3e-28
Identities = 92/284 (32%), Positives = 145/284 (50%), Gaps = 30/284 (10%)
Query: 145 VGSGTFGHVLVAEKVDHNMKRQ-VAKKTVSYAVKVINTAKTRMVKEATILEKLN-HPNII 202
VG G FGH A+ MK Q VA K +S A + + +E +L+ L+ H +++
Sbjct: 149 VGRGHFGHTCWAKAKKGKMKNQTVAVKIISKAKMTSTLSIEDVRREVKLLKALSGHRHMV 208
Query: 203 RIHQSCVDALGNVYIFQDLISGGDLFS-YLAKGDCLVPISETESLIIIYQILLALKFLHS 261
+ + DA NV++ +L GG+L LA+G E ++ I+ QIL A F H
Sbjct: 209 KFYDVYEDA-DNVFVVMELCEGGELLDRILARGG---RYPEVDAKRILVQILSATAFFHL 264
Query: 262 NGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFK 321
G+VHRDLK +N L + + + DFG++ + + +R++ VVG+ Y APEV
Sbjct: 265 QGVVHRDLKPENFLFTSRNEDAILKVIDFGLSDFIRYD--QRLNDVVGSAYYVAPEV--- 319
Query: 322 ADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVRT 381
++RS Y ++ D+WS+GVI++I+L G PFYG +E++I + V
Sbjct: 320 ----LHRS-------------YSTEADMWSIGVISYILLCGSRPFYG-RTESAIFRCVLR 361
Query: 382 GKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWV 425
NF W +I+ +AK FVK+ L R +AL W+
Sbjct: 362 ANPNFEDMPWPSISPTAKDFVKRLLNKDHRKRMTAAQALAHPWL 405
>At2g46700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 595
Score = 124 bits (311), Expect = 3e-28
Identities = 91/284 (32%), Positives = 141/284 (49%), Gaps = 30/284 (10%)
Query: 145 VGSGTFGHVLVAEKVDHNMK-RQVAKKTVSYAVKVINTAKTRMVKEATILEKLN-HPNII 202
VG G FGH ++K +A K +S A A + +E +L+ L+ H +I
Sbjct: 149 VGRGHFGHTCSGRGKKGDIKDHPIAVKIISKAKMTTAIAIEDVRREVKLLKSLSGHKYLI 208
Query: 203 RIHQSCVDALGNVYIFQDLISGGDLFS-YLAKGDCLVPISETESLIIIYQILLALKFLHS 261
+ + +C DA NVYI +L GG+L LA+G E ++ I+ QIL + F H
Sbjct: 209 KYYDACEDA-NNVYIVMELCDGGELLDRILARGG---KYPEDDAKAIVVQILTVVSFCHL 264
Query: 262 NGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFK 321
G+VHRDLK +N L + + + L DFG++ + + ER++ +VG+ Y APEV
Sbjct: 265 QGVVHRDLKPENFLFTSSREDSDLKLIDFGLSDFIRPD--ERLNDIVGSAYYVAPEV--- 319
Query: 322 ADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVRT 381
++RS+S A DIWS+GVIT+I+L G PF+ +E+ I + V
Sbjct: 320 ----LHRSYSLEA-------------DIWSIGVITYILLCGSRPFWA-RTESGIFRTVLR 361
Query: 382 GKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWV 425
+ N+ W + + K FVK+ L R +AL W+
Sbjct: 362 TEPNYDDVPWPSCSSEGKDFVKRLLNKDYRKRMSAVQALTHPWL 405
>At5g66210 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 523
Score = 123 bits (308), Expect = 7e-28
Identities = 90/290 (31%), Positives = 146/290 (50%), Gaps = 32/290 (11%)
Query: 141 VPRIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKLN-HP 199
+ +++G G FG+ VA + +VA K + + V+ A + +E IL L+ H
Sbjct: 64 IGKLLGHGQFGYTYVA--IHRPNGDRVAVKRLDKSKMVLPIAVEDVKREVQILIALSGHE 121
Query: 200 NIIRIHQSCVDALGNVYIFQDLISGGDLFSYLA--KGDCLVPISETESLIIIYQILLALK 257
N+++ H + D VYI +L GG+L + KG+ SE ++ +++ Q+L
Sbjct: 122 NVVQFHNAFEDD-DYVYIVMELCEGGELLDRILSKKGN---RYSEKDAAVVVRQMLKVAG 177
Query: 258 FLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPE 317
H +G+VHRD+K +N L + + + + DFG++ + +R H +VG+ Y APE
Sbjct: 178 ECHLHGLVHRDMKPENFLFKSAQLDSPLKATDFGLSDFIKPG--KRFHDIVGSAYYVAPE 235
Query: 318 VGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIK 377
V + +G +S D+WS+GVIT+I+L G PF+ D +E I K
Sbjct: 236 VLKR------------------RSGPES--DVWSIGVITYILLCGRRPFW-DRTEDGIFK 274
Query: 378 NVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEK 427
V K +F+ + W I+DSAK FVKK L R +AL WV +
Sbjct: 275 EVLRNKPDFSRKPWATISDSAKDFVKKLLVKDPRARLTAAQALSHAWVRE 324
>Hs4759050 [T] KOG0603 Ribosomal protein S6 kinase
Length = 740
Score = 122 bits (307), Expect = 9e-28
Identities = 106/359 (29%), Positives = 163/359 (44%), Gaps = 58/359 (16%)
Query: 92 RDVPYLLSNQDVIQLPNGAKFKFSAVKSETMSQFMTGLRIKS----------EWDRWKIV 141
+D P + + + QL G F F A+ S+ SQ M + + S ++ V
Sbjct: 367 KDSPGIPPSANAHQLFRG--FSFVAITSDDESQAMQTVGVHSIVQQLHRNSIQFTDGYEV 424
Query: 142 PRIVGSGTFGHVLVAEKVDHNMKRQVAKKT-VSYAVKVINTAKTRMVKEATILEKLN-HP 199
+G G++ KR + K T + +AVK+I+ +K +E IL + HP
Sbjct: 425 KEDIGVGSYSVC----------KRCIHKATNMEFAVKIIDKSKRDPTEEIEILLRYGQHP 474
Query: 200 NIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFL 259
NII + + D VY+ +L+ GG+L + + SE E+ +++ I +++L
Sbjct: 475 NIITL-KDVYDDGKYVYVVTELMKGGELLDKILRQKFF---SEREASAVLFTITKTVEYL 530
Query: 260 HSNGIVHRDLKLDNILL----HTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCA 315
H+ G+VHRDLK NIL PE + + DFG AK+L M T T + A
Sbjct: 531 HAQGVVHRDLKPSNILYVDESGNPE---SIRICDFGFAKQLRAENGLLM-TPCYTANFVA 586
Query: 316 PEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYG--DGSEA 373
PEV GYD+ CDIWSLGV+ + MLTG +PF D +
Sbjct: 587 PEV-------------------LKRQGYDAACDIWSLGVLLYTMLTGYTPFANGPDDTPE 627
Query: 374 SIIKNVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKHTSQL 432
I+ + +GK + + W +++D+AK V K L V R L W+ H QL
Sbjct: 628 EILARIGSGKFSLSGGYWNSVSDTAKDLVSKMLHVDPHQRLTAALVLRHPWI-VHWDQL 685
Score = 114 bits (285), Expect = 3e-25
Identities = 78/232 (33%), Positives = 122/232 (51%), Gaps = 39/232 (16%)
Query: 143 RIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTA------KTRMVKEATILEKL 196
+++G G+FG V + +K+ + RQ+ YA+KV+ A + R E IL ++
Sbjct: 72 KVLGQGSFGKVFLVKKISGSDARQL------YAMKVLKKATLKVRDRVRTKMERDILVEV 125
Query: 197 NHPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLAL 256
NHP I+++H + G +Y+ D + GGDLF+ L+K V +E + + ++ LAL
Sbjct: 126 NHPFIVKLHYA-FQTEGKLYLILDFLRGGDLFTRLSKE---VMFTEEDVKFYLAELALAL 181
Query: 257 KFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAP 316
LHS GI++RDLK +NILL + + L DFG++KE S + +++ ++ GT EY AP
Sbjct: 182 DHLHSLGIIYRDLKPENILL---DEEGHIKLTDFGLSKE-SIDHEKKAYSFCGTVEYMAP 237
Query: 317 EVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYG 368
EV + G+ D WS GV+ MLTG PF G
Sbjct: 238 EV-------------------VNRRGHTQSADWWSFGVLMFEMLTGTLPFQG 270
>At4g09570 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 501
Score = 122 bits (307), Expect = 9e-28
Identities = 85/288 (29%), Positives = 142/288 (48%), Gaps = 31/288 (10%)
Query: 145 VGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKLN-HPNIIR 203
+G G FG + + + A K++ V + +E I+ L+ HPN++R
Sbjct: 31 LGQGQFGTTYLC--TEKSSSANYACKSIPKRKLVCREDYEDVWREIQIMHHLSEHPNVVR 88
Query: 204 IHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHSNG 263
I + D++ V+I ++ GG+LF + C SE E+ +I IL ++ HS G
Sbjct: 89 IKGTYEDSVF-VHIVMEVCEGGELFDRIVSKGCF---SEREAAKLIKTILGVVEACHSLG 144
Query: 264 IVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKAD 323
++HRDLK +N L +P K+ DFG++ + + ++ VVG+P Y APEV K
Sbjct: 145 VMHRDLKPENFLFDSPSDDAKLKATDFGLS--VFYKPGQYLYDVVGSPYYVAPEVLKKC- 201
Query: 324 RNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVRTGK 383
Y + D+WS GVI +I+L+G+ PF+ + +E+ I + + GK
Sbjct: 202 -------------------YGPEIDVWSAGVILYILLSGVPPFWAE-TESGIFRQILQGK 241
Query: 384 LNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVW-VEKHTS 430
++F + W I++ AK + K L S R EAL W V++H +
Sbjct: 242 IDFKSDPWPTISEGAKDLIYKMLDRSPKKRISAHEALCHPWIVDEHAA 289
>At1g35670 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 495
Score = 122 bits (306), Expect = 1e-27
Identities = 85/283 (30%), Positives = 144/283 (50%), Gaps = 32/283 (11%)
Query: 145 VGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKLN-HPNIIR 203
+G G FG + + + A K++ V + +E I+ L+ HPN++R
Sbjct: 32 LGQGQFGTTYLC--TEKSTSANYACKSIPKRKLVCREDYEDVWREIQIMHHLSEHPNVVR 89
Query: 204 IHQSCVDALGNVYIFQDLISGGDLFSYL-AKGDCLVPISETESLIIIYQILLALKFLHSN 262
I + D++ V+I ++ GG+LF + +KG SE E++ +I IL ++ HS
Sbjct: 90 IKGTYEDSVF-VHIVMEVCEGGELFDRIVSKGH----FSEREAVKLIKTILGVVEACHSL 144
Query: 263 GIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKA 322
G++HRDLK +N L +P+ K+ DFG++ + + ++ VVG+P Y APEV K
Sbjct: 145 GVMHRDLKPENFLFDSPKDDAKLKATDFGLS--VFYKPGQYLYDVVGSPYYVAPEVLKKC 202
Query: 323 DRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVRTG 382
Y + D+WS GVI +I+L+G+ PF+ + +E+ I + + G
Sbjct: 203 --------------------YGPEIDVWSAGVILYILLSGVPPFWAE-TESGIFRQILQG 241
Query: 383 KLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWV 425
KL+F + W I+++AK + K L+ S R EAL W+
Sbjct: 242 KLDFKSDPWPTISEAAKDLIYKMLERSPKKRISAHEALCHPWI 284
>Hs7657526 [T] KOG0603 Ribosomal protein S6 kinase
Length = 745
Score = 122 bits (305), Expect = 2e-27
Identities = 87/276 (31%), Positives = 129/276 (46%), Gaps = 29/276 (10%)
Query: 168 AKKTVSYAVKVINTAKTRMVKEATILEKLN-HPNIIRIHQSCVDALGNVYIFQDLISGGD 226
A + +AVK+I+ +K +E IL + HPNII + + D VY+ DL+ GG+
Sbjct: 446 ATTNMEFAVKIIDKSKRDPSEEIEILMRYGQHPNIITL-KDVFDDGRYVYLVTDLMKGGE 504
Query: 227 LFSYLAKGDCLVPISETESLIIIYQILLALKFLHSNGIVHRDLKLDNIL-LHTPEPCTKV 285
L + K C SE E+ I+Y I + +LH G+VHRDLK NIL + +
Sbjct: 505 LLDRILKQKCF---SEREASDILYVISKTVDYLHCQGVVHRDLKPSNILYMDESASADSI 561
Query: 286 VLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKADRNIYRSFSRTATLDPDNNGYDS 345
+ DFG AK+L + + T T + APEV + GYD+
Sbjct: 562 RICDFGFAKQL-RGENGLLLTPCYTANFVAPEVLMQ-------------------QGYDA 601
Query: 346 KCDIWSLGVITHIMLTGISPFYGDGSEA--SIIKNVRTGKLNFTARQWIAITDSAKSFVK 403
CDIWSLGV+ + ML G +PF ++ I+ + GK + + W I+D AK +
Sbjct: 602 ACDIWSLGVLFYTMLAGYTPFANGPNDTPEEILLRIGNGKFSLSGGNWDNISDGAKDLLS 661
Query: 404 KCLQVSTFNRCDVEEALHQVWVEKHTSQLERIYKKK 439
L + R E+ L W+ H QL K+
Sbjct: 662 HMLHMDPHQRYTAEQILKHSWI-THRDQLPNDQPKR 696
Score = 110 bits (275), Expect = 5e-24
Identities = 93/305 (30%), Positives = 155/305 (50%), Gaps = 45/305 (14%)
Query: 143 RIVGSGTFGHV-LVAEKVDHNMKRQVAKKTVSYA-VKVINTAKTRMVKEATILEKLNHPN 200
+++G G+FG V LV +K + + A K + A +KV + +T+M E IL ++NHP
Sbjct: 77 KVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLKKASLKVRDRVRTKM--ERDILVEVNHPF 134
Query: 201 IIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLH 260
I+++H + G +Y+ D + GGD+F+ L+K V +E + + ++ LAL LH
Sbjct: 135 IVKLHYA-FQTEGKLYLILDFLRGGDVFTRLSKE---VLFTEEDVKFYLAELALALDHLH 190
Query: 261 SNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGF 320
GIV+RDLK +NILL + + L DFG++KE S + +++ ++ GT EY APEV
Sbjct: 191 QLGIVYRDLKPENILL---DEIGHIKLTDFGLSKE-SVDQEKKAYSFCGTVEYMAPEV-- 244
Query: 321 KADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYG-DGSEA-SIIKN 378
+ G+ D WS GV+ MLTG PF G D +E ++I
Sbjct: 245 -----------------VNRRGHSQSADWWSYGVLMFEMLTGTLPFQGKDRNETMNMILK 287
Query: 379 VRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRC---DVEEALHQVWVEKHTSQLERI 435
+ G F ++ A+S ++ + + NR VEE ++ +++
Sbjct: 288 AKLGMPQF-------LSAEAQSLLRMLFKRNPANRLGSEGVEEIKRHLFFA--NIDWDKL 338
Query: 436 YKKKV 440
YK++V
Sbjct: 339 YKREV 343
>HsM4505191 [T] KOG0607 MAP kinase-interacting kinase and related
serine/threonine protein kinases
Length = 424
Score = 121 bits (304), Expect = 2e-27
Identities = 92/340 (27%), Positives = 155/340 (45%), Gaps = 53/340 (15%)
Query: 136 DRWKIVPRIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINT----AKTRMVKEA- 190
D +K+ ++G G + V A + + + YAVK+I +++R+ +E
Sbjct: 46 DMYKLTSELLGEGAYAKVQGAVSLQNGKE---------YAVKIIEKQAGHSRSRVFREVE 96
Query: 191 TILEKLNHPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIY 250
T+ + + NI+ + + D +F+ L GG + +++ K +E E+ ++
Sbjct: 97 TLYQCQGNKNILELIEFFEDDTRFYLVFEKL-QGGSILAHIQKQK---HFNEREASRVVR 152
Query: 251 QILLALKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQN------TKERM 304
+ AL FLH+ GI HRDLK +NIL +PE + V + DF + + N T +
Sbjct: 153 DVAAALDFLHTKGIAHRDLKPENILCESPEKVSPVKICDFDLGSGMKLNNSCTPITTPEL 212
Query: 305 HTVVGTPEYCAPEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGIS 364
T G+ EY APEV F+ AT YD +CD+WSLGV+ +IML+G
Sbjct: 213 TTPCGSAEYMAPEV--------VEVFTDQATF------YDKRCDLWSLGVVLYIMLSGYP 258
Query: 365 PFYG--------DGSEA------SIIKNVRTGKLNFTARQWIAITDSAKSFVKKCLQVST 410
PF G D E + ++++ GK F + W I+ AK + K L
Sbjct: 259 PFVGHCGADCGWDRGEVCRVCQNKLFESIQEGKYEFPDKDWAHISSEAKDLISKLLVRDA 318
Query: 411 FNRCDVEEALHQVWVEKHTSQLERIYKKKVLQLSSDCIKI 450
R + L WV+ + + + +VLQ +S + +
Sbjct: 319 KQRLSAAQVLQHPWVQGQAPE-KGLPTPQVLQRNSSTMDL 357
>Hs20149547 [T] KOG0603 Ribosomal protein S6 kinase
Length = 735
Score = 121 bits (304), Expect = 2e-27
Identities = 90/270 (33%), Positives = 131/270 (48%), Gaps = 35/270 (12%)
Query: 164 KRQVAKKT-VSYAVKVINTAKTRMVKEATILEKLN-HPNIIRIHQSCVDALGNVYIFQDL 221
KR V K T + YAVKVI+ +K +E IL + HPNII + + D +VY+ +L
Sbjct: 433 KRCVHKATNMEYAVKVIDKSKRDPSEEIEILLRYGQHPNIITL-KDVYDDGKHVYLVTEL 491
Query: 222 ISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHSNGIVHRDLKLDNILL----H 277
+ GG+L + + SE E+ +++ I +++LHS G+VHRDLK NIL
Sbjct: 492 MRGGELLDKILRQKFF---SEREASFVLHTIGKTVEYLHSQGVVHRDLKPSNILYVDESG 548
Query: 278 TPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKADRNIYRSFSRTATLD 337
PE C ++ DFG AK+L M T T + APEV
Sbjct: 549 NPE-CLRI--CDFGFAKQLRAENGLLM-TPCYTANFVAPEV------------------- 585
Query: 338 PDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEA--SIIKNVRTGKLNFTARQWIAIT 395
GYD CDIWSLG++ + ML G +PF S+ I+ + +GK + W ++
Sbjct: 586 LKRQGYDEGCDIWSLGILLYTMLAGYTPFANGPSDTPEEILTRIGSGKFTLSGGNWNTVS 645
Query: 396 DSAKSFVKKCLQVSTFNRCDVEEALHQVWV 425
++AK V K L V R ++ L WV
Sbjct: 646 ETAKDLVSKMLHVDPHQRLTAKQVLQHPWV 675
Score = 108 bits (269), Expect = 2e-23
Identities = 77/231 (33%), Positives = 117/231 (50%), Gaps = 37/231 (16%)
Query: 143 RIVGSGTFGHVLVAEKVD-----HNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKLN 197
+++G G+FG V + KV H +V KK +KV + +T+M E IL +N
Sbjct: 66 KVLGQGSFGKVFLVRKVTRPDSGHLYAMKVLKKAT---LKVRDRVRTKM--ERDILADVN 120
Query: 198 HPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALK 257
HP ++++H + G +Y+ D + GGDLF+ L+K V +E + + ++ L L
Sbjct: 121 HPFVVKLHYA-FQTEGKLYLILDFLRGGDLFTRLSKE---VMFTEEDVKFYLAELALGLD 176
Query: 258 FLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPE 317
LHS GI++RDLK +NILL + + L DFG++KE + K + ++ GT EY APE
Sbjct: 177 HLHSLGIIYRDLKPENILL---DEEGHIKLTDFGLSKEAIDHEK-KAYSFCGTVEYMAPE 232
Query: 318 VGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYG 368
V + G+ D WS GV+ MLTG PF G
Sbjct: 233 V-------------------VNRQGHSHSADWWSYGVLMFEMLTGSLPFQG 264
>At3g49370 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 594
Score = 121 bits (304), Expect = 2e-27
Identities = 93/286 (32%), Positives = 144/286 (49%), Gaps = 30/286 (10%)
Query: 143 RIVGSGTFGHVLVAEKVDHNMKRQ-VAKKTVSYAVKVINTAKTRMVKEATILEKLN-HPN 200
R VG G FGH A+ +K Q VA K +S + + + +E +L+ L+ H +
Sbjct: 146 REVGRGHFGHTCWAKAKKGKIKGQTVAVKIISKSKMTSALSIEDVRREVKLLKALSGHSH 205
Query: 201 IIRIHQSCVDALGNVYIFQDLISGGDLF-SYLAKGDCLVPISETESLIIIYQILLALKFL 259
+++ + D+ NV++ +L GG+L S LA+G E E+ I+ QIL A F
Sbjct: 206 MVKFYDVFEDS-DNVFVVMELCEGGELLDSILARGG---RYPEAEAKRILVQILSATAFF 261
Query: 260 HSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVG 319
H G+VHRDLK +N L + + + DFG++ +R++ VVG+ Y APEV
Sbjct: 262 HLQGVVHRDLKPENFLFTSKNEDAVLKVIDFGLSD--YARFDQRLNDVVGSAYYVAPEV- 318
Query: 320 FKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNV 379
++RS Y ++ DIWS+GVI++I+L G PFYG +E++I + V
Sbjct: 319 ------LHRS-------------YSTEADIWSIGVISYILLCGSRPFYG-RTESAIFRCV 358
Query: 380 RTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWV 425
NF W +I+ AK FVK+ L R +AL W+
Sbjct: 359 LRANPNFDDLPWPSISPIAKDFVKRLLNKDHRKRMTAAQALAHPWL 404
>CE18967 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD and related
proteins
Length = 1101
Score = 121 bits (303), Expect = 3e-27
Identities = 96/344 (27%), Positives = 163/344 (46%), Gaps = 43/344 (12%)
Query: 102 DVIQLPNGAKFKFSAVKSETMSQFMTGLRIKSEWDRWKIVPRIVGSGTFGHVLVAEKVDH 161
D +++P + K +T +F +I +E ++GSG FG V +
Sbjct: 741 DKLKVPTEGETGHLGAKIQTEHEFSQLYQIFAE--------EVLGSGQFGTVYGG--IHR 790
Query: 162 NMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKLNHPNIIRIHQSCVDALGNVYIFQDL 221
+ VA K + +K + + E ILEK++HP ++ Q ++ +++ +
Sbjct: 791 RNGQHVAVKLID-KLKFPPNKEDLLRAEVQILEKVDHPGVVHFMQM-LETTDRIFVVMEK 848
Query: 222 ISGGDLFSYLA--KGDCLVPISETESLIIIYQILLALKFLHSNGIVHRDLKLDNILLHTP 279
+ G L L+ KG +SE + ++ QIL AL++LH IVH DLK +NILL++
Sbjct: 849 LKGDMLEMILSSEKGR----LSERTTQFLVAQILEALRYLHHLNIVHCDLKPENILLNSN 904
Query: 280 EPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKADRNIYRSFSRTATLDPD 339
+V L DFG A+ + + + R +VVGTP Y APEV
Sbjct: 905 SDFPQVKLCDFGFARIIGEKSFRR--SVVGTPAYLAPEV-------------------LR 943
Query: 340 NNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVRTGKLNFTARQWIAITDSAK 399
N G++ D+WS+GVI ++ L+G PF + I ++ + + W I+++A
Sbjct: 944 NKGFNRSLDMWSVGVIVYVSLSGTFPF---NEDEDINDQIQNAEFMYPPTPWKEISENAI 1000
Query: 400 SFVKKCLQVSTFNRCDVEEALHQVWVEKHTSQLE-RIYKKKVLQ 442
F+ LQV R V +A Q+W++ +T + R+ +K V Q
Sbjct: 1001 EFINGLLQVKMSKRYTVTKAQSQIWMQNYTLWSDLRVLEKAVGQ 1044
>CE27583 [T] KOG0604 MAP kinase-activated protein kinase 2
Length = 425
Score = 120 bits (301), Expect = 5e-27
Identities = 80/298 (26%), Positives = 141/298 (46%), Gaps = 37/298 (12%)
Query: 138 WKIVPRIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVI-NTAKTRMVKEATILEKL 196
++I +++G G G V+ E RQ K +A+KV+ +T K R E ++
Sbjct: 71 YRISRKVLGVGINGKVVECEH------RQSGDK---FALKVLRDTQKARREVELHVMAS- 120
Query: 197 NHPNIIRIHQSCVDALGNV---YIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQIL 253
H +++ +H ++ V + + + GG+LF+ + + +E E+ I+ +I
Sbjct: 121 GHGHVVSVHDVYKNSYNGVDCLLVVMENMKGGELFNRIQERGQKA-FTEREAAGIVNEIC 179
Query: 254 LALKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEY 313
A+ LH I HRDLK +N+L T + L DFG AK+ ++ + + T TP Y
Sbjct: 180 SAVAHLHRMSIAHRDLKPENLLYVTTASNAALKLTDFGFAKKTDESEPQGLKTACFTPYY 239
Query: 314 CAPEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFY---GDG 370
CAPEV YD CD+WS+GVI +I+L G PFY G
Sbjct: 240 CAPEV-------------------LGTEKYDKSCDLWSIGVIMYILLCGYPPFYSQHGQP 280
Query: 371 SEASIIKNVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKH 428
+ +++G+ F + +W ++++AK ++K L+ R +E+ + W+ +
Sbjct: 281 MSPGMKAKIKSGQYTFPSPEWDCVSEAAKDLIRKLLRTEPTERITIEQTMEHKWISHY 338
>CE17545 [T] KOG0604 MAP kinase-activated protein kinase 2
Length = 443
Score = 120 bits (301), Expect = 5e-27
Identities = 80/298 (26%), Positives = 141/298 (46%), Gaps = 37/298 (12%)
Query: 138 WKIVPRIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVI-NTAKTRMVKEATILEKL 196
++I +++G G G V+ E RQ K +A+KV+ +T K R E ++
Sbjct: 89 YRISRKVLGVGINGKVVECEH------RQSGDK---FALKVLRDTQKARREVELHVMAS- 138
Query: 197 NHPNIIRIHQSCVDALGNV---YIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQIL 253
H +++ +H ++ V + + + GG+LF+ + + +E E+ I+ +I
Sbjct: 139 GHGHVVSVHDVYKNSYNGVDCLLVVMENMKGGELFNRIQERGQKA-FTEREAAGIVNEIC 197
Query: 254 LALKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEY 313
A+ LH I HRDLK +N+L T + L DFG AK+ ++ + + T TP Y
Sbjct: 198 SAVAHLHRMSIAHRDLKPENLLYVTTASNAALKLTDFGFAKKTDESEPQGLKTACFTPYY 257
Query: 314 CAPEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFY---GDG 370
CAPEV YD CD+WS+GVI +I+L G PFY G
Sbjct: 258 CAPEV-------------------LGTEKYDKSCDLWSIGVIMYILLCGYPPFYSQHGQP 298
Query: 371 SEASIIKNVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKH 428
+ +++G+ F + +W ++++AK ++K L+ R +E+ + W+ +
Sbjct: 299 MSPGMKAKIKSGQYTFPSPEWDCVSEAAKDLIRKLLRTEPTERITIEQTMEHKWISHY 356
>CE18169 [T] KOG0603 Ribosomal protein S6 kinase
Length = 797
Score = 120 bits (300), Expect = 6e-27
Identities = 91/301 (30%), Positives = 146/301 (48%), Gaps = 32/301 (10%)
Query: 156 AEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKLNHPN-IIRIHQSCVDALGN 214
A V H + + ++ YAVK++ A +E IL + +H ++++ D
Sbjct: 464 AHSVVHKCQMKATRR--KYAVKIVKKAVFDATEEVDILLRHSHHQFVVKLFDVYEDETA- 520
Query: 215 VYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHSNGIVHRDLKLDNI 274
+Y+ ++L GG+L L L SE E I+ +L A+++LHS + HRDL NI
Sbjct: 521 IYMIEELCEGGELLDKLVNKKSLG--SEKEVAAIMANLLNAVQYLHSQQVAHRDLTAANI 578
Query: 275 L--LHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKADRNIYRSFSR 332
L L +P + + + DFG AK+ S+ + T T ++ APEV K
Sbjct: 579 LFALKDGDP-SSLRIVDFGFAKQ-SRAENGMLMTPCYTAQFVAPEVLRK----------- 625
Query: 333 TATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEA--SIIKNVRTGKLNFTARQ 390
GYD CD+WSLGV+ H MLTG +PF ++ I++ V GK++ T
Sbjct: 626 --------QGYDRSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQILQRVGDGKISMTHPV 677
Query: 391 WIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKHTSQLER-IYKKKVLQLSSDCIK 449
W I+D AK V+K L V R ++AL W+ + + +R I ++V +L +K
Sbjct: 678 WDTISDEAKDLVRKMLDVDPNRRVTAKQALQHKWIGQKEALPDRPIQSEQVGELDMQNVK 737
Query: 450 I 450
+
Sbjct: 738 V 738
Score = 109 bits (273), Expect = 8e-24
Identities = 77/231 (33%), Positives = 123/231 (52%), Gaps = 37/231 (16%)
Query: 143 RIVGSGTFGHVLVAEKV-----DHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKLN 197
+++G G+FG V + KV H +V KK +KV + +T++ E IL ++
Sbjct: 108 KVLGQGSFGKVFLVRKVRGRDSGHVYAMKVLKKAT---LKVRDRQRTKL--ERNILAHIS 162
Query: 198 HPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALK 257
HP I+++H + G +Y+ D + GGDLF+ L+K V +E + + ++ LAL+
Sbjct: 163 HPFIVKLHYA-FQTEGKLYLILDFLRGGDLFTRLSKE---VMFTEDDVKFYLAELTLALE 218
Query: 258 FLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPE 317
LHS GIV+RDLK +NILL + + + DFG++KE + +++++ ++ GT EY APE
Sbjct: 219 HLHSLGIVYRDLKPENILL---DADGHIKVTDFGLSKE-AIDSEKKTYSFCGTVEYMAPE 274
Query: 318 VGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYG 368
V + G+ D WSLGV+ MLTG PF G
Sbjct: 275 V-------------------INRRGHSMAADFWSLGVLMFEMLTGHLPFQG 306
>CE13014 [T] KOG0603 Ribosomal protein S6 kinase
Length = 740
Score = 120 bits (300), Expect = 6e-27
Identities = 91/301 (30%), Positives = 146/301 (48%), Gaps = 32/301 (10%)
Query: 156 AEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKLNHPN-IIRIHQSCVDALGN 214
A V H + + ++ YAVK++ A +E IL + +H ++++ D
Sbjct: 407 AHSVVHKCQMKATRR--KYAVKIVKKAVFDATEEVDILLRHSHHQFVVKLFDVYEDETA- 463
Query: 215 VYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHSNGIVHRDLKLDNI 274
+Y+ ++L GG+L L L SE E I+ +L A+++LHS + HRDL NI
Sbjct: 464 IYMIEELCEGGELLDKLVNKKSLG--SEKEVAAIMANLLNAVQYLHSQQVAHRDLTAANI 521
Query: 275 L--LHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKADRNIYRSFSR 332
L L +P + + + DFG AK+ S+ + T T ++ APEV K
Sbjct: 522 LFALKDGDP-SSLRIVDFGFAKQ-SRAENGMLMTPCYTAQFVAPEVLRK----------- 568
Query: 333 TATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEA--SIIKNVRTGKLNFTARQ 390
GYD CD+WSLGV+ H MLTG +PF ++ I++ V GK++ T
Sbjct: 569 --------QGYDRSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQILQRVGDGKISMTHPV 620
Query: 391 WIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKHTSQLER-IYKKKVLQLSSDCIK 449
W I+D AK V+K L V R ++AL W+ + + +R I ++V +L +K
Sbjct: 621 WDTISDEAKDLVRKMLDVDPNRRVTAKQALQHKWIGQKEALPDRPIQSEQVGELDMQNVK 680
Query: 450 I 450
+
Sbjct: 681 V 681
Score = 109 bits (273), Expect = 8e-24
Identities = 77/231 (33%), Positives = 123/231 (52%), Gaps = 37/231 (16%)
Query: 143 RIVGSGTFGHVLVAEKV-----DHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKLN 197
+++G G+FG V + KV H +V KK +KV + +T++ E IL ++
Sbjct: 51 KVLGQGSFGKVFLVRKVRGRDSGHVYAMKVLKKAT---LKVRDRQRTKL--ERNILAHIS 105
Query: 198 HPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALK 257
HP I+++H + G +Y+ D + GGDLF+ L+K V +E + + ++ LAL+
Sbjct: 106 HPFIVKLHYA-FQTEGKLYLILDFLRGGDLFTRLSKE---VMFTEDDVKFYLAELTLALE 161
Query: 258 FLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPE 317
LHS GIV+RDLK +NILL + + + DFG++KE + +++++ ++ GT EY APE
Sbjct: 162 HLHSLGIVYRDLKPENILL---DADGHIKVTDFGLSKE-AIDSEKKTYSFCGTVEYMAPE 217
Query: 318 VGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYG 368
V + G+ D WSLGV+ MLTG PF G
Sbjct: 218 V-------------------INRRGHSMAADFWSLGVLMFEMLTGHLPFQG 249
>At1g49580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 606
Score = 120 bits (300), Expect = 6e-27
Identities = 90/297 (30%), Positives = 146/297 (48%), Gaps = 42/297 (14%)
Query: 145 VGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMV-------KEATILEKLN 197
+G G FG+ A+ +K QV AVK+I +K +E IL+ L+
Sbjct: 156 IGRGHFGYTCSAKFKKGELKGQVV------AVKIIPKSKMTTAIAIEDVRREVKILQALS 209
Query: 198 -HPNIIRIHQSCVDALGNVYIFQDLISGGDLFS-YLAKGDCLVPISETESLIIIYQILLA 255
H N+++ + + D NVYI +L GG+L LA+G SE ++ +I QIL
Sbjct: 210 GHKNLVQFYDAFEDN-ANVYIAMELCEGGELLDRILARGG---KYSENDAKPVIIQILNV 265
Query: 256 LKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCA 315
+ F H G+VHRDLK +N L + E +++ DFG++ + + ER++ +VG+ Y A
Sbjct: 266 VAFCHFQGVVHRDLKPENFLYTSKEENSQLKAIDFGLSDFVRPD--ERLNDIVGSAYYVA 323
Query: 316 PEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASI 375
PEV ++RS Y ++ D+WS+GVI +I+L G PF+ +E+ I
Sbjct: 324 PEV-------LHRS-------------YTTEADVWSIGVIAYILLCGSRPFWA-RTESGI 362
Query: 376 IKNVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKHTSQL 432
+ V +F W ++ AK FVK+ L R +AL W+ + + +
Sbjct: 363 FRAVLKADPSFDEPPWPFLSSDAKDFVKRLLFKDPRRRMSASQALMHPWIRAYNTDM 419
>7295638 [T] KOG0603 Ribosomal protein S6 kinase
Length = 911
Score = 120 bits (300), Expect = 6e-27
Identities = 92/300 (30%), Positives = 143/300 (47%), Gaps = 54/300 (18%)
Query: 145 VGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEAT----------ILE 194
+G GTF V +H ++ YAVKVI A +T +L
Sbjct: 574 LGRGTFS---VCRLCEHRASKK------HYAVKVIEKAAVAAASTSTSADCWEEVEIMLR 624
Query: 195 KLNHPNIIRIHQSCVDALGNVYIFQDLISGGDLFS-YLAKGDCLVPISETESLIIIYQIL 253
NHPNI+ ++ DA G+ Y+ +L+ GG+L LA G + E+E+ ++ I
Sbjct: 625 YGNHPNIVTLYSVYEDA-GSAYLVMELLKGGELLDRILAVGQ----MCESEASAVLRTIA 679
Query: 254 LALKFLHSNGIVHRDLKLDNILL----HTPEPCTKVVLADFGIAKELSQNTKERMHTVVG 309
A+ +LH +G+VHRDLK N++ TPE + L D G AK+L + M T
Sbjct: 680 SAVAYLHEHGVVHRDLKPSNMIYASMRQTPET---LKLCDLGFAKQLRADNGLLM-TPCY 735
Query: 310 TPEYCAPEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGD 369
T + APEV GYD CDIWSLGV+ +IML+G +PF
Sbjct: 736 TANFVAPEV-------------------LKRQGYDLACDIWSLGVLLYIMLSGRTPFAST 776
Query: 370 GSEAS--IIKNVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEK 427
+++ I+K + +G+++FT+ +W I+ AK +++ L + NR L W+ +
Sbjct: 777 PNDSPDVILKRIGSGQIDFTSSRWALISVPAKELLRQMLHIVPENRPTAARILEHDWLRE 836
Score = 106 bits (265), Expect = 7e-23
Identities = 75/246 (30%), Positives = 124/246 (49%), Gaps = 42/246 (17%)
Query: 143 RIVGSGTFGHVLVAEKVDHNMKRQVAKKTVS-YAVKVINTA------KTRMVKEATILEK 195
R++G G+FG V + K+ + K + YA+KV+ A + R E IL
Sbjct: 203 RVLGEGSFGKVFLVRKI-------IGKDAGTLYAMKVLKKATLKVKDRVRSTNERKILAD 255
Query: 196 LNHPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLA 255
+ H I+R+H + G +Y+ D + GGDLF+ L+K V +E + + ++ LA
Sbjct: 256 VGHAFIVRLHYA-FQTPGKLYLILDFLRGGDLFTRLSKE---VMFTEEDVKFYLAELALA 311
Query: 256 LKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCA 315
+ LH+ GI++RDLK +NILL + + L DFG++K+ +K ++ GT EY A
Sbjct: 312 MNHLHTLGIIYRDLKPENILL---DEHGHIALTDFGLSKQPLDGSK--TYSFCGTVEYMA 366
Query: 316 PEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASI 375
PE+ + G+D D WS GV+ + MLTG PF+G + ++
Sbjct: 367 PEI-------------------VNRKGHDFAADWWSFGVLMYEMLTGNLPFHGQTRQETM 407
Query: 376 IKNVRT 381
+ +R+
Sbjct: 408 NQILRS 413
>Hs19923468 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD and related
proteins
Length = 878
Score = 119 bits (299), Expect = 8e-27
Identities = 87/297 (29%), Positives = 144/297 (48%), Gaps = 31/297 (10%)
Query: 138 WKIVP-RIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKL 196
++I P ++GSG FG V + R VA K + ++ ++++ E IL+ L
Sbjct: 549 YQIFPDEVLGSGQFGVVYGGKH--RKTGRDVAVKVID-KLRFPTKQESQLRNEVAILQSL 605
Query: 197 NHPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLAL 256
HP I+ + + + V++ + + G L L+ +P T+ LI QIL+AL
Sbjct: 606 RHPGIVNL-ECMFETPEKVFVVMEKLHGDMLEMILSSEKGRLPERLTKFLIT--QILVAL 662
Query: 257 KFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAP 316
+ LH IVH DLK +N+LL + +P +V L DFG A+ + + + R +VVGTP Y AP
Sbjct: 663 RHLHFKNIVHCDLKPENVLLASADPFPQVKLCDFGFARIIGEKSFRR--SVVGTPAYLAP 720
Query: 317 EVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASII 376
EV N GY+ D+WS+GVI ++ L+G PF + I
Sbjct: 721 EVLL-------------------NQGYNRSLDMWSVGVIMYVSLSGTFPF---NEDEDIN 758
Query: 377 KNVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKHTSQLE 433
++ + A W I+ A + LQV R V+++L W++++ + L+
Sbjct: 759 DQIQNAAFMYPASPWSHISAGAIDLINNLLQVKMRKRYSVDKSLSHPWLQEYQTWLD 815
>CE12518 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 391
Score = 119 bits (298), Expect = 1e-26
Identities = 82/283 (28%), Positives = 140/283 (48%), Gaps = 37/283 (13%)
Query: 144 IVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKLNHPNIIR 203
+VG G+F VL +V H + R+ +AVKV+N + E IL +L+HP +IR
Sbjct: 76 VVGKGSFSQVL---RVQHRVTRKY------FAVKVVNGDCGAVNNELNILSRLSHPFVIR 126
Query: 204 IHQSCVDALGNVYIFQDLISGGDLFS-YLAKGDCLVPISETESLIIIYQILLALKFLHSN 262
+ + + ++I + SGG+++ +AKG SE E+ + +L L +LHS
Sbjct: 127 LEE-VFKSSSKLFIVMQMASGGEMYDRVVAKGR----YSEEEARNALKMLLTGLTYLHSI 181
Query: 263 GIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKA 322
+ HRDLK +N+L P ++++ DFG+A + ++ E M GTPEY APE+ +
Sbjct: 182 RVTHRDLKPENLLYADSRPEARLLITDFGLAYQATK-PNETMTETCGTPEYIAPELLLRV 240
Query: 323 DRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVRTG 382
Y K D+W++GVI +I+++GI PF D + + ++ T
Sbjct: 241 P-------------------YTQKVDMWAVGVIAYILMSGIMPF-DDDCRSRLYTHIITA 280
Query: 383 KLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWV 425
+ + W ++ AK FV L+ ++ R A+ W+
Sbjct: 281 NYVYYPQFWSG-SELAKQFVDSLLETNSVERLSSSAAMKHEWL 322
>Hs4502567_1 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 360
Score = 119 bits (298), Expect = 1e-26
Identities = 87/310 (28%), Positives = 147/310 (47%), Gaps = 44/310 (14%)
Query: 144 IVGSGTFGHVLVAEKVDHNMKRQVAKKT-VSYAVKVINTAKTR---------MVKEATIL 193
++G G F V +R + ++T +AVK+++ AK + +EA+I
Sbjct: 17 VIGKGPFSVV----------RRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASIC 66
Query: 194 EKLNHPNIIRIHQSCVDALGNVYIFQDLISGGDL-FSYLAKGDCLVPISETESLIIIYQI 252
L HP+I+ + ++ + G +Y+ + + G DL F + + D SE + + QI
Sbjct: 67 HMLKHPHIVELLET-YSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQI 125
Query: 253 LLALKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPE 312
L AL++ H N I+HRD+K +LL + E V L FG+A +L ++ VGTP
Sbjct: 126 LEALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGR-VGTPH 184
Query: 313 YCAPEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSE 372
+ APEV Y D+W GVI I+L+G PFY G++
Sbjct: 185 FMAPEV-------------------VKREPYGKPVDVWGCGVILFILLSGCLPFY--GTK 223
Query: 373 ASIIKNVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKHTSQL 432
+ + + GK RQW I++SAK V++ L + R V EAL+ W+++
Sbjct: 224 ERLFEGIIKGKYKMNPRQWSHISESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYA 283
Query: 433 ERIYKKKVLQ 442
+I+ + ++
Sbjct: 284 YKIHLPETVE 293
>Hs19923570 [T] KOG0603 Ribosomal protein S6 kinase
Length = 733
Score = 119 bits (297), Expect = 1e-26
Identities = 88/267 (32%), Positives = 126/267 (46%), Gaps = 29/267 (10%)
Query: 164 KRQVAKKT-VSYAVKVINTAKTRMVKEATILEKLN-HPNIIRIHQSCVDALGNVYIFQDL 221
KR V K T YAVK+I+ +K +E IL + HPNII + + D VY+ +L
Sbjct: 430 KRCVHKATDTEYAVKIIDKSKRDPSEEIEILLRYGQHPNIITL-KDVYDDGKFVYLVMEL 488
Query: 222 ISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHSNGIVHRDLKLDNILLHTPEP 281
+ GG+L + + SE E+ ++ I + +LHS G+VHRDLK NIL
Sbjct: 489 MRGGELLDRILRQRYF---SEREASDVLCTITKTMDYLHSQGVVHRDLKPSNILYRDESG 545
Query: 282 CTKVV-LADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKADRNIYRSFSRTATLDPDN 340
+ + + DFG AK+L M T T + APEV
Sbjct: 546 SPESIRVCDFGFAKQLRAGNGLLM-TPCYTANFVAPEV-------------------LKR 585
Query: 341 NGYDSKCDIWSLGVITHIMLTGISPFYG--DGSEASIIKNVRTGKLNFTARQWIAITDSA 398
GYD+ CDIWSLG++ + ML G +PF D + I+ + +GK + W +I+D+A
Sbjct: 586 QGYDAACDIWSLGILLYTMLAGFTPFANGPDDTPEEILARIGSGKYALSGGNWDSISDAA 645
Query: 399 KSFVKKCLQVSTFNRCDVEEALHQVWV 425
K V K L V R + L WV
Sbjct: 646 KDVVSKMLHVDPHQRLTAMQVLKHPWV 672
Score = 110 bits (274), Expect = 6e-24
Identities = 77/232 (33%), Positives = 118/232 (50%), Gaps = 39/232 (16%)
Query: 143 RIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTA------KTRMVKEATILEKL 196
+++G G++G V + KV + Q+ YA+KV+ A + R E IL ++
Sbjct: 63 KVLGQGSYGKVFLVRKVKGSDAGQL------YAMKVLKKATLKVRDRVRSKMERDILAEV 116
Query: 197 NHPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLAL 256
NHP I+++H + G +Y+ D + GGDLF+ L+K V +E + + ++ LAL
Sbjct: 117 NHPFIVKLHYA-FQTEGKLYLILDFLRGGDLFTRLSKE---VMFTEEDVKFYLAELALAL 172
Query: 257 KFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAP 316
LHS GI++RDLK +NILL + + + DFG++KE + K R ++ GT EY AP
Sbjct: 173 DHLHSLGIIYRDLKPENILL---DEEGHIKITDFGLSKEAIDHDK-RAYSFCGTIEYMAP 228
Query: 317 EVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYG 368
EV + G+ D WS GV+ MLTG PF G
Sbjct: 229 EV-------------------VNRRGHTQSADWWSFGVLMFEMLTGSLPFQG 261
>Hs14993776 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 596
Score = 119 bits (297), Expect = 1e-26
Identities = 80/300 (26%), Positives = 150/300 (49%), Gaps = 33/300 (11%)
Query: 145 VGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKLNHPNIIRI 204
+G G FG V + +K +A K + K K ++ E ++ +LNH N+I++
Sbjct: 291 LGGGKFGAVCTCMEKATGLK--LAAKVIK---KQTPKDKEMVLLEIEVMNQLNHRNLIQL 345
Query: 205 HQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHSNGI 264
+ + ++ + +F + I GG+LF + D ++E ++++ + QI + F+H +
Sbjct: 346 Y-AAIETPHEIVLFMEYIEGGELFERIVDED--YHLTEVDTMVFVRQICDGILFMHKMRV 402
Query: 265 VHRDLKLDNIL-LHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKAD 323
+H DLK +NIL ++T K++ DFG+A+ + N K +++ GTPE+ +PEV
Sbjct: 403 LHLDLKPENILCVNTTGHLVKII--DFGLARRYNPNEKLKVN--FGTPEFLSPEV----- 453
Query: 324 RNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVRTGK 383
+ + K D+WS+GVIT+++L+G+SPF GD + + NV +G
Sbjct: 454 --------------VNYDQISDKTDMWSMGVITYMLLSGLSPFLGD-DDTETLNNVLSGN 498
Query: 384 LNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKHTSQLERIYKKKVLQL 443
F + A++D AK FV + R + + L W+ + +R ++ Q+
Sbjct: 499 WYFDEETFEAVSDEAKDFVSNLIVKDQRARMNAAQCLAHPWLNNLAEKAKRCNRRLKSQI 558
>At4g30960 [T] KOG0583 Serine/threonine protein kinase
Length = 441
Score = 119 bits (297), Expect = 1e-26
Identities = 85/293 (29%), Positives = 145/293 (49%), Gaps = 40/293 (13%)
Query: 143 RIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVK-EATILEKLNHPNI 201
R++G GTF V A + + VA K V KV+ +K E +++ + HPNI
Sbjct: 28 RLLGHGTFAKVYHARNIQTG--KSVAMKVVGKE-KVVKVGMVDQIKREISVMRMVKHPNI 84
Query: 202 IRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHS 261
+ +H+ + + +Y +L+ GG+LF+ +AKG + E + + Q++ A+ F HS
Sbjct: 85 VELHE-VMASKSKIYFAMELVRGGELFAKVAKGR----LREDVARVYFQQLISAVDFCHS 139
Query: 262 NGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKE--RMHTVVGTPEYCAPEVG 319
G+ HRDLK +N+LL + + + DFG++ +++ K+ +HT GTP Y APEV
Sbjct: 140 RGVYHRDLKPENLLL---DEEGNLKVTDFGLS-AFTEHLKQDGLLHTTCGTPAYVAPEVI 195
Query: 320 FKADRNIYRSFSRTATLDPDNNGYD-SKCDIWSLGVITHIMLTGISPFYGDGSEASIIKN 378
K GYD +K D+WS GVI ++L G PF D + ++ +
Sbjct: 196 LK-------------------KGYDGAKADLWSCGVILFVLLAGYLPFQ-DDNLVNMYRK 235
Query: 379 VRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKHTSQ 431
+ G +F W ++ A+ V K L + R +E+ + W +K ++
Sbjct: 236 IYRG--DFKCPGW--LSSDARRLVTKLLDPNPNTRITIEKVMDSPWFKKQATR 284
>At3g50530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 601
Score = 119 bits (297), Expect = 1e-26
Identities = 86/284 (30%), Positives = 138/284 (48%), Gaps = 28/284 (9%)
Query: 145 VGSGTFGHVLVAE-KVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKLNHPNIIR 203
VG G FG+ A+ K N +QVA K + A A + +E IL L+ N +
Sbjct: 154 VGRGHFGYTCAAKFKKGDNKGQQVAVKVIPKAKMTTAIAIEDVRREVKILRALSGHNNLP 213
Query: 204 IHQSCVDALGNVYIFQDLISGGDLFS-YLAKGDCLVPISETESLIIIYQILLALKFLHSN 262
+ NVYI +L GG+L L++G +E ++ ++ QIL + F H
Sbjct: 214 HFYDAYEDHDNVYIVMELCEGGELLDRILSRGG---KYTEEDAKTVMIQILNVVAFCHLQ 270
Query: 263 GIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKA 322
G+VHRDLK +N L + E +++ DFG++ + + ER++ +VG+ Y APEV
Sbjct: 271 GVVHRDLKPENFLFTSKEDTSQLKAIDFGLSDYVRPD--ERLNDIVGSAYYVAPEV---- 324
Query: 323 DRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVRTG 382
++RS Y ++ DIWS+GVI +I+L G PF+ +E+ I + V
Sbjct: 325 ---LHRS-------------YSTEADIWSVGVIVYILLCGSRPFWA-RTESGIFRAVLKA 367
Query: 383 KLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVE 426
+F W ++ A+ FVK+ L R +AL W++
Sbjct: 368 DPSFDDPPWPLLSSEARDFVKRLLNKDPRKRLTAAQALSHPWIK 411
>7292679 [G] KOG0599 Phosphorylase kinase gamma subunit
Length = 560
Score = 119 bits (297), Expect = 1e-26
Identities = 83/282 (29%), Positives = 141/282 (49%), Gaps = 38/282 (13%)
Query: 154 LVAEKVDHNMKRQVAKKT-VSYAVKVINTAKTRMV-------------KEATILEK-LNH 198
++ + ++R + K+T +A K+I+ T +E +IL + + H
Sbjct: 28 ILGRGISSTVRRCIEKETGKEFAAKIIDLGATTESGETNPYHMLEATRQEISILRQVMGH 87
Query: 199 PNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKF 258
P II + Q ++ V++ +L G+LF YL +V +SE ++ I+ QI +++
Sbjct: 88 PYIIDL-QDVFESDAFVFLVFELCPKGELFDYLTS---VVTLSEKKTRTIMRQIFEGVEY 143
Query: 259 LHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEV 318
+H+ IVHRDLK +NILL V + DFG AK+L + E++ + GTP Y APE
Sbjct: 144 IHAKSIVHRDLKPENILLDENH---NVKITDFGFAKQLQEG--EKLTNLCGTPGYLAPE- 197
Query: 319 GFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKN 378
+ + + GY + DIW+ GVI +L G PF+ + +++N
Sbjct: 198 ------------TLKCNMFEGSPGYSQEVDIWACGVIMFTLLVGCPPFW-HRKQMVMLRN 244
Query: 379 VRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEAL 420
+ GK +FT+ +W I++ K ++KCL V R V+E L
Sbjct: 245 IMEGKYSFTSPEWADISEDPKDLIRKCLVVDPSQRITVKEVL 286
>CE05507 [T] KOG0603 Ribosomal protein S6 kinase
Length = 785
Score = 118 bits (296), Expect = 2e-26
Identities = 85/318 (26%), Positives = 155/318 (48%), Gaps = 32/318 (10%)
Query: 144 IVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTA-KTRMVKEATILEKLN-HPNI 201
++G G F V E+V + +AVK+++ ++ +EA ILE + HPNI
Sbjct: 387 LLGKGAFSVVRRCERVVDGAQ---------FAVKIVSQKFASQAQREARILEMVQGHPNI 437
Query: 202 IRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHS 261
+++H D L + Y+ ++++G +L + K L +E+E+ I+ Q++ A+K+LH
Sbjct: 438 VQLHDVHSDPL-HFYLVMEILTGNELLERIRK---LERFTESEAADIMRQLVSAVKYLHD 493
Query: 262 NGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFK 321
IVHRDLK +NIL + + ++ L DFG A+ L + ++++ +V + G
Sbjct: 494 KRIVHRDLKPENILFESIDSSARLRLVDFGFARLLPNSMEQQLKSV----QVLRKMYGLI 549
Query: 322 ADRNIYRSFSRTATLD----------PDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGS 371
A + S + TL Y+ +CD+WSLGV+ ML+G PF+
Sbjct: 550 AHNHSLHSETPCFTLQYAAPEVLDVGDSQPEYNEQCDLWSLGVVLFTMLSGQVPFHARSR 609
Query: 372 EAS---IIKNVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKH 428
+ S I++ + + +FT W ++ AK+ + L V R ++E +W++
Sbjct: 610 QESATEIMQRICRAEFSFTGDAWTNVSADAKNLITGLLTVDPKKRLSMQELTAHMWLKSS 669
Query: 429 TSQLERIYKKKVLQLSSD 446
S + +L S+D
Sbjct: 670 ASMDTPLQTPSILPSSAD 687
Score = 97.8 bits (242), Expect = 3e-20
Identities = 82/277 (29%), Positives = 134/277 (47%), Gaps = 42/277 (15%)
Query: 143 RIVGSGTFGHVLVAEKV---DHNM--KRQVAKKTVSYAVKVINTAKT--RMVKEATILEK 195
R++G G +G V + KV DHN +V +KT +V+ KT + E +LE+
Sbjct: 21 RVLGKGAYGKVFLVRKVGGKDHNTIYAMKVLRKT-----RVLTKQKTLEHTMAERQVLER 75
Query: 196 LNH-PNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESL-IIIYQIL 253
L P ++ + + ++I + + GG+LF++L C + E+ +I +++
Sbjct: 76 LRGTPFLVNLFYA-FQTDTKLHIVMEYVRGGELFTHL----CSRGHFDLEAARFVIAELV 130
Query: 254 LALKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEY 313
+A+ LH +++RDLKL+NILL V L DFG++K +R ++ GT EY
Sbjct: 131 VAIDSLHQRKVIYRDLKLENILLDEEG---HVKLTDFGLSKLFLPGELDRANSYCGTIEY 187
Query: 314 CAPEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEA 373
+PEV ++ GY D WSLGVI+ +LTG SPF DG++
Sbjct: 188 MSPEV-----------------INRPEGGYSDVVDWWSLGVISFELLTGCSPFTVDGAQN 230
Query: 374 S---IIKNVRTGKLNFTARQWIAITDSAKSFVKKCLQ 407
S I K + T K+ F + D ++K L+
Sbjct: 231 SSKDIAKRIMTKKVPFPKTMDVDARDFIGQLLEKKLE 267
>At5g23580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 490
Score = 118 bits (296), Expect = 2e-26
Identities = 82/284 (28%), Positives = 136/284 (47%), Gaps = 30/284 (10%)
Query: 143 RIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKLN-HPNI 201
+++G G FG + K +A K++ + +++E I+ L+ +PN+
Sbjct: 26 QVLGQGQFGTTFLCTHKQTGQK--LACKSIPKRKLLCQEDYDDVLREIQIMHHLSEYPNV 83
Query: 202 IRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHS 261
+RI +S + NV++ +L GG+LF + K SE E+ +I I+ ++ HS
Sbjct: 84 VRI-ESAYEDTKNVHLVMELCEGGELFDRIVKRG---HYSEREAAKLIKTIVGVVEACHS 139
Query: 262 NGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFK 321
G+VHRDLK +N L + + + DFG++ + E +VG+ Y APEV K
Sbjct: 140 LGVVHRDLKPENFLFSSSDEDASLKSTDFGLSVFCTPG--EAFSELVGSAYYVAPEVLHK 197
Query: 322 ADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVRT 381
Y +CD+WS GVI +I+L G PF+ + SE I + +
Sbjct: 198 H--------------------YGPECDVWSAGVILYILLCGFPPFWAE-SEIGIFRKILQ 236
Query: 382 GKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWV 425
GKL F W +I++SAK +KK L+ + R + L W+
Sbjct: 237 GKLEFEINPWPSISESAKDLIKKMLESNPKKRLTAHQVLCHPWI 280
>Hs4826684_1 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 370
Score = 118 bits (296), Expect = 2e-26
Identities = 79/273 (28%), Positives = 142/273 (51%), Gaps = 41/273 (15%)
Query: 172 VSYAVKVINTAKTR----------MVKEATILEKLNHPNIIRIHQSCVDALGNVYIFQDL 221
+ YA K I +T+ + +E +IL+++ HPN+I +H+ + +V + +L
Sbjct: 37 LQYAAKFIKKRRTKSSRRGVSREDIEREVSILKEIQHPNVITLHE-VYENKTDVILILEL 95
Query: 222 ISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHSNGIVHRDLKLDNILL---HT 278
++GG+LF +LA+ + L +E E+ + QIL + +LHS I H DLK +NI+L +
Sbjct: 96 VAGGELFDFLAEKESL---TEEEATEFLKQILNGVYYLHSLQIAHFDLKPENIMLLDRNV 152
Query: 279 PEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKADRNIYRSFSRTATLDP 338
P+P K++ DFG+A ++ + + + GTPE+ APE+ +P
Sbjct: 153 PKPRIKII--DFGLAHKIDFGNEFK--NIFGTPEFVAPEI---------------VNYEP 193
Query: 339 DNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVRTGKLNFTARQWIAITDSA 398
+ D+WS+GVIT+I+L+G SPF GD ++ + NV F + + A
Sbjct: 194 ----LGLEADMWSIGVITYILLSGASPFLGD-TKQETLANVSAVNYEFEDEYFSNTSALA 248
Query: 399 KSFVKKCLQVSTFNRCDVEEALHQVWVEKHTSQ 431
K F+++ L R ++++L W++ +Q
Sbjct: 249 KDFIRRLLVKDPKKRMTIQDSLQHPWIKPKDTQ 281
>7290629 [T] KOG0604 MAP kinase-activated protein kinase 2
Length = 359
Score = 118 bits (295), Expect = 2e-26
Identities = 73/235 (31%), Positives = 118/235 (50%), Gaps = 27/235 (11%)
Query: 200 NIIRIHQSCVDALGNVYIFQDLISGGDLFSYLA-KGDCLVPISETESLIIIYQILLALKF 258
NII ++++ + + + + GG+LF + K D +E E+ I+++I A+ +
Sbjct: 75 NIIDVYENTFKDRKCLLVVMECMEGGELFQRIQDKADGA--FTEREAAQIMHEICAAVDY 132
Query: 259 LHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEV 318
LHS I HRDLK +N+L T +P + L DFG AKE T + T TP Y APEV
Sbjct: 133 LHSRDIAHRDLKPENLLYTTTQPNATLKLTDFGFAKETF--TSYTLQTPCYTPYYVAPEV 190
Query: 319 GFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEA---SI 375
L P+ YD CDIWSLGV+ +I++ G PFY + A +
Sbjct: 191 -----------------LGPEK--YDKSCDIWSLGVVMYIIMCGFPPFYSNHGLAISPGM 231
Query: 376 IKNVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKHTS 430
+RTG+ +F +W ++ +AK +K L V R +++ + W+ ++ +
Sbjct: 232 KNRIRTGQYDFPDPEWTNVSQAAKDLIKGMLNVDPSKRLRIQDVISNKWIAQYNA 286
>At1g30270 [T] KOG0583 Serine/threonine protein kinase
Length = 480
Score = 117 bits (293), Expect = 4e-26
Identities = 84/286 (29%), Positives = 136/286 (47%), Gaps = 35/286 (12%)
Query: 143 RIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKLNHPNII 202
R +G GTF V A V++ VA K + + N ++ +E + ++ + HPN+I
Sbjct: 35 RTLGEGTFAKVKFARNVENG--DNVAIKVIDKEKVLKNKMIAQIKREISTMKLIKHPNVI 92
Query: 203 RIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHSN 262
R+ + +Y + ++GG+LF ++ L E E+ Q++ A+ + HS
Sbjct: 93 RMFEVMASKT-KIYFVLEFVTGGELFDKISSNGRL---KEDEARKYFQQLINAVDYCHSR 148
Query: 263 GIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKA 322
G+ HRDLK +N+LL + + ++DFG++ L Q +HT GTP Y APEV
Sbjct: 149 GVYHRDLKPENLLL---DANGALKVSDFGLS-ALPQQEDGLLHTTCGTPNYVAPEV---- 200
Query: 323 DRNIYRSFSRTATLDPDNNGYD-SKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVRT 381
+N GYD +K D+WS GVI +++ G PF D + S+ K +
Sbjct: 201 ---------------INNKGYDGAKADLWSCGVILFVLMAGYLPF-EDSNLTSLYKKI-- 242
Query: 382 GKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEK 427
K FT W + SAK +K+ L + R E + W +K
Sbjct: 243 FKAEFTCPPWFSA--SAKKLIKRILDPNPATRITFAEVIENEWFKK 286
>7300778 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 450
Score = 117 bits (293), Expect = 4e-26
Identities = 89/305 (29%), Positives = 145/305 (47%), Gaps = 45/305 (14%)
Query: 144 IVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAK---------TRMVKEATILE 194
++G G F + + H Q +AVK+++ AK + +EATI
Sbjct: 17 VIGKGPFS---IVRRCIHRESNQ------QFAVKIVDVAKFTASPGLSTADLKREATICH 67
Query: 195 KLNHPNIIRIHQSCVDALGNVYIFQDLISGGDL-FSYLAKGDCLVPISETESLIIIYQIL 253
L HP+I+ + ++ + G +Y+ + + G DL F + + SE + + QIL
Sbjct: 68 MLKHPHIVELLET-YSSEGMLYMVFEFMEGSDLCFEVVRRAVAGFVYSEAVACHYMRQIL 126
Query: 254 LALKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERM--HTVVGTP 311
AL++ H N I+HRD++ LL T + V L FG A +L T+E + H VG P
Sbjct: 127 EALRYCHENDILHRDVRPACALLATVDNSAPVKLGGFGSAIQLP-GTRETIETHGRVGCP 185
Query: 312 EYCAPEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGS 371
Y APEV R +Y CD+W GV+ H++L+G PF G G
Sbjct: 186 HYMAPEV---VTRRLY----------------GKGCDVWGAGVMLHVLLSGRLPFLGSG- 225
Query: 372 EASIIKNVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKHTSQ 431
+ ++V G+L+F A +W +I+ +AK V K L + +R + E L W+ + +
Sbjct: 226 -VRLQQSVARGRLSFEAPEWKSISANAKDLVMKMLAANPHHRLSITEVLDHPWI-RDRDK 283
Query: 432 LERIY 436
L+R +
Sbjct: 284 LQRTH 288
>Hs4557511 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 454
Score = 117 bits (292), Expect = 5e-26
Identities = 74/248 (29%), Positives = 131/248 (51%), Gaps = 31/248 (12%)
Query: 182 AKTRMVKEATILEKLNHPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPIS 241
++ + +E IL ++ HPNII +H + +V + +L+SGG+LF +LA+ + L +
Sbjct: 57 SREEIEREVNILREIRHPNIITLHD-IFENKTDVVLILELVSGGELFDFLAEKESL---T 112
Query: 242 ETESLIIIYQILLALKFLHSNGIVHRDLKLDNILL---HTPEPCTKVVLADFGIAKELSQ 298
E E+ + QIL + +LHS I H DLK +NI+L + P P ++ L DFGIA ++
Sbjct: 113 EDEATQFLKQILDGVHYLHSKRIAHFDLKPENIMLLDKNVPNP--RIKLIDFGIAHKIEA 170
Query: 299 NTKERMHTVVGTPEYCAPEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHI 358
+ + + GTPE+ APE+ +P + D+WS+GVIT+I
Sbjct: 171 GNEFK--NIFGTPEFVAPEI---------------VNYEP----LGLEADMWSIGVITYI 209
Query: 359 MLTGISPFYGDGSEASIIKNVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEE 418
+L+G SPF G+ ++ + N+ +F + ++ AK F+++ L R + +
Sbjct: 210 LLSGASPFLGE-TKQETLTNISAVNYDFDEEYFSNTSELAKDFIRRLLVKDPKRRMTIAQ 268
Query: 419 ALHQVWVE 426
+L W++
Sbjct: 269 SLEHSWIK 276
>Hs4759052 [T] KOG0603 Ribosomal protein S6 kinase
Length = 809
Score = 116 bits (291), Expect = 7e-26
Identities = 83/290 (28%), Positives = 134/290 (45%), Gaps = 41/290 (14%)
Query: 145 VGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTA-KTRMVKEATILEKLN-HPNII 202
+G G+F + K H Q + VK+I+ + KE T L+ HPNI+
Sbjct: 432 LGEGSFS---ICRKCVHKKSNQALQ------VKIISKRMEANTQKEITALKLCEGHPNIV 482
Query: 203 RIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHSN 262
++H+ D L + ++ +L++GG+LF L K SETE+ I+ +++ AL +H
Sbjct: 483 KLHEVFHDQL-HTFLVMELLNGGELFDALRKKK---HFSETEASYIMRKLVSALSHMHDL 538
Query: 263 GIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKA 322
G+VHRDLK +N+L ++ + DFG A+ L + + T T C PE+
Sbjct: 539 GVVHRDLKPENLLFTDENDNLEIKIIDFGFAR-LKPPDNQPLKTPCFTLHSCRPEL---- 593
Query: 323 DRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDG------SEASII 376
+ NGYD CD+WSLGVI + ML+G PF S I+
Sbjct: 594 ---------------LNQNGYDESCDLWSLGVILYTMLSGQVPFQSHDRSLTCTSAVEIM 638
Query: 377 KNVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVE 426
K ++ G +F W ++ AK ++ L V R + + W++
Sbjct: 639 KKIKKGDFSFEGEAWKNVSQEAKDLIQGLLTVDPNKRLKMSGLRYNEWLQ 688
Score = 116 bits (290), Expect = 9e-26
Identities = 82/261 (31%), Positives = 139/261 (52%), Gaps = 28/261 (10%)
Query: 117 VKSETMSQFMTGLRIKSEWDRWKIVPRIVGSGTFGHVLVAEKVD-HNMKRQVAKKTVSYA 175
VK E + +TG K + ++++ +++G+G +G V + K+ H+ + A K + A
Sbjct: 28 VKHELRTANLTGHAEKVGIENFELL-KVLGTGAYGKVFLVRKISGHDTGKLYAMKVLKKA 86
Query: 176 VKVINTAKTRMVK-EATILEKLNH-PNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAK 233
V T + E +LE + P ++ +H + +++ D I+GG+LF++L++
Sbjct: 87 TIVQKAKTTEHTRTERQVLEHIRQSPFLVTLHYA-FQTETKLHLILDYINGGELFTHLSQ 145
Query: 234 GDCLVPISETESLIIIYQILLALKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIA 293
+ +E E I + +I+LAL+ LH GI++RD+KL+NILL + VVL DFG++
Sbjct: 146 RE---RFTEHEVQIYVGEIVLALEHLHKLGIIYRDIKLENILL---DSNGHVVLTDFGLS 199
Query: 294 KELSQNTKERMHTVVGTPEYCAPEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLG 353
KE + ER ++ GT EY AP++ D +G+D D WSLG
Sbjct: 200 KEFVADETERAYSFCGTIEYMAPDIVRGGD-----------------SGHDKAVDWWSLG 242
Query: 354 VITHIMLTGISPFYGDGSEAS 374
V+ + +LTG SPF DG + S
Sbjct: 243 VLMYELLTGASPFTVDGEKNS 263
>Hs4506735 [T] KOG0603 Ribosomal protein S6 kinase
Length = 772
Score = 116 bits (291), Expect = 7e-26
Identities = 77/262 (29%), Positives = 125/262 (47%), Gaps = 32/262 (12%)
Query: 174 YAVKVINTAKTRMVKEATILEKL--NHPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYL 231
+AVK+++ + +L +HPN++ +H+ D L + Y+ +L+ GG+L ++
Sbjct: 437 FAVKILSRRLEANTQREVAALRLCQSHPNVVNLHEVHHDQL-HTYLVLELLRGGELLEHI 495
Query: 232 AKGDCLVPISETESLIIIYQILLALKFLHSN-GIVHRDLKLDNILLHTPEPCTKVVLADF 290
K SE+E+ I+ ++ A+ F+H G+VHRDLK +NIL P V + DF
Sbjct: 496 RKKR---HFSESEASQILRSLVSAVSFMHEEAGVVHRDLKPENILYADDTPGAPVKIIDF 552
Query: 291 GIAKELSQNTKERMHTVVGTPEYCAPEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIW 350
G A+ Q+ M T T +Y APE+ GYD CD+W
Sbjct: 553 GFARLRPQSPGVPMQTPCFTLQYAAPEL-------------------LAQQGYDESCDLW 593
Query: 351 SLGVITHIMLTGISPFYGDGSE------ASIIKNVRTGKLNFTARQWIAITDSAKSFVKK 404
SLGVI ++ML+G PF G + A I+ +R G+ + W +++ AK V+
Sbjct: 594 SLGVILYMMLSGQVPFQGASGQGGQSQAAEIMCKIREGRFSLDGEAWQGVSEEAKELVRG 653
Query: 405 CLQVSTFNRCDVEEALHQVWVE 426
L V R +E W++
Sbjct: 654 LLTVDPAKRLKLEGLRGSSWLQ 675
Score = 102 bits (254), Expect = 1e-21
Identities = 81/260 (31%), Positives = 134/260 (51%), Gaps = 33/260 (12%)
Query: 116 AVKSETMSQFMTGLRIKSEWDRWKIVPRIVGSGTFGHVLVAEKVD-HNMKRQVAKKTVSY 174
AV+ +TG K + ++++ +++G+G +G V + K H+ + A K +
Sbjct: 11 AVELRITEANLTGHEEKVSVENFELL-KVLGTGAYGKVFLVRKAGGHDAGKLYAMKVLRK 69
Query: 175 AVKVINTAKTR--MVKEATILEKLNH-PNIIRIHQSC-VDALGNVYIFQDLISGGDLFSY 230
A ++ AKT+ E ++LE + P ++ +H + DA +++ D +SGG++F++
Sbjct: 70 AA-LVQRAKTQEHTRTERSVLELVRQAPFLVTLHYAFQTDA--KLHLILDYVSGGEMFTH 126
Query: 231 LAKGDCLVPISETESLIIIYQILLALKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADF 290
L + E E + +I+LAL+ LH GI++RDLKL+N+LL + +VL DF
Sbjct: 127 LYQRQYF---KEAEVRVYGGEIVLALEHLHKLGIIYRDLKLENVLLDSEG---HIVLTDF 180
Query: 291 GIAKELSQNTKERMHTVVGTPEYCAPEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIW 350
G++KE KER + GT EY APE I RS G+ D W
Sbjct: 181 GLSKEFLTEEKERTFSFCGTIEYMAPE--------IIRS----------KTGHGKAVDWW 222
Query: 351 SLGVITHIMLTGISPFYGDG 370
SLG++ +LTG SPF +G
Sbjct: 223 SLGILLFELLTGASPFTLEG 242
>At3g19100 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 599
Score = 116 bits (291), Expect = 7e-26
Identities = 89/290 (30%), Positives = 142/290 (48%), Gaps = 42/290 (14%)
Query: 145 VGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMV-------KEATILEKLN 197
+G G FG+ A+ +K Q AVKVI +K +E IL L+
Sbjct: 150 IGRGHFGYTCSAKFKKGELKDQ------EVAVKVIPKSKMTSAISIEDVRREVKILRALS 203
Query: 198 -HPNIIRIHQSCVDALGNVYIFQDLISGGDLFS-YLAKGDCLVPISETESLIIIYQILLA 255
H N+++ + + D NVYI +L GG+L LA+G SE ++ ++ QIL
Sbjct: 204 GHQNLVQFYDAFEDN-ANVYIVMELCGGGELLDRILARGG---KYSEDDAKAVLIQILNV 259
Query: 256 LKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCA 315
+ F H G+VHRDLK +N L + E + + + DFG++ + + ER++ +VG+ Y A
Sbjct: 260 VAFCHLQGVVHRDLKPENFLYTSKEENSMLKVIDFGLSDFVRPD--ERLNDIVGSAYYVA 317
Query: 316 PEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASI 375
PEV ++RS Y ++ D+WS+GVI +I+L G PF+ +E+ I
Sbjct: 318 PEV-------LHRS-------------YTTEADVWSIGVIAYILLCGSRPFWA-RTESGI 356
Query: 376 IKNVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWV 425
+ V +F W +++ AK FVK+ L R +AL W+
Sbjct: 357 FRAVLKADPSFDEPPWPSLSFEAKDFVKRLLYKDPRKRMTASQALMHPWI 406
>Hs5453882 [G] KOG0599 Phosphorylase kinase gamma subunit
Length = 387
Score = 116 bits (290), Expect = 9e-26
Identities = 96/310 (30%), Positives = 154/310 (48%), Gaps = 42/310 (13%)
Query: 154 LVAEKVDHNMKRQVAKKTVS-YAVKVINTA--------KTRMVKEAT-----ILEKLN-H 198
++ V ++R + K T YAVKVI+ + R ++EAT IL K++ H
Sbjct: 25 ILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEVDILRKVSGH 84
Query: 199 PNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKF 258
PNII++ + +F DL+ G+LF YL + V +SE E+ I+ +L +
Sbjct: 85 PNIIQLKDTYETNTFFFLVF-DLMKRGELFDYLTEK---VTLSEKETRKIMRALLEVICT 140
Query: 259 LHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEV 318
LH IVHRDLK +NILL + + L DFG + +L ER+ V GTP Y APE+
Sbjct: 141 LHKLNIVHRDLKPENILL---DDNMNIKLTDFGFSCQLEPG--ERLREVCGTPSYLAPEI 195
Query: 319 GFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKN 378
+++ D+ GY + D+WS GVI + +L G PF+ + +++
Sbjct: 196 -------------IECSMNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFW-HRKQMLMLRM 241
Query: 379 VRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKHTSQLERIY-- 436
+ +G F + +W +D+ K V + L V NR EEAL + +++ + R +
Sbjct: 242 IMSGNYQFGSPEWDDYSDTVKDLVSRFLVVQPQNRYTAEEALAHPFFQQYLVEEVRHFSP 301
Query: 437 --KKKVLQLS 444
K KV+ L+
Sbjct: 302 RGKFKVIALT 311
>Hs4758700 [T] KOG0604 MAP kinase-activated protein kinase 2
Length = 382
Score = 116 bits (290), Expect = 9e-26
Identities = 81/270 (30%), Positives = 131/270 (48%), Gaps = 30/270 (11%)
Query: 217 IFQDLISGGDLFSYLA-KGDCLVPISETESLIIIYQILLALKFLHSNGIVHRDLKLDNIL 275
I + + GG+LFS + +GD +E E+ I+ I A++FLHS+ I HRD+K +N+L
Sbjct: 116 IIMECMEGGELFSRIQERGD--QAFTEREAAEIMRDIGTAIQFLHSHNIAHRDVKPENLL 173
Query: 276 LHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKADRNIYRSFSRTAT 335
+ E + L DFG AKE +QN + T TP Y APEV
Sbjct: 174 YTSKEKDAVLKLTDFGFAKETTQNA---LQTPCYTPYYVAPEV----------------- 213
Query: 336 LDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEA---SIIKNVRTGKLNFTARQWI 392
L P+ YD CD+WSLGVI +I+L G PFY + +A + + +R G+ F +W
Sbjct: 214 LGPEK--YDKSCDMWSLGVIMYILLCGFPPFYSNTGQAISPGMKRRIRLGQYGFPNPEWS 271
Query: 393 AITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKHTSQLER-IYKKKVLQLSSD-CIKI 450
+++ AK ++ L+ R + + ++ W+ + + ++ +VLQ D ++
Sbjct: 272 EVSEDAKQLIRLLLKTDPTERLTITQFMNHPWINQSMVVPQTPLHTARVLQEDKDHWDEV 331
Query: 451 DENIDTFAVVKHKLPKSVKLSPEKNPNKRL 480
E + + VK+ K N RL
Sbjct: 332 KEEMTSALATMRVDYDQVKIKDLKTSNNRL 361
>Hs4506075 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD and related
proteins
Length = 912
Score = 116 bits (290), Expect = 9e-26
Identities = 85/297 (28%), Positives = 142/297 (47%), Gaps = 31/297 (10%)
Query: 138 WKIVP-RIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKL 196
++I P ++GSG FG V + R VA K + ++ ++++ E IL+ L
Sbjct: 581 YQIFPDEVLGSGQFGIVYGGKH--RKTGRDVAIKIID-KLRFPTKQESQLRNEVAILQNL 637
Query: 197 NHPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLAL 256
+HP ++ + + + V++ + + G L L+ +P T+ LI QIL+AL
Sbjct: 638 HHPGVVNL-ECMFETPERVFVVMEKLHGDMLEMILSSEKGRLPEHITKFLIT--QILVAL 694
Query: 257 KFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAP 316
+ LH IVH DLK +N+LL + +P +V L DFG A+ + + + R +VVGTP Y AP
Sbjct: 695 RHLHFKNIVHCDLKPENVLLASADPFPQVKLCDFGFARIIGEKSFRR--SVVGTPAYLAP 752
Query: 317 EVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASII 376
EV N GY+ D+WS+GVI ++ L+G PF + I
Sbjct: 753 EV-------------------LRNKGYNRSLDMWSVGVIIYVSLSGTFPF---NEDEDIH 790
Query: 377 KNVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKHTSQLE 433
++ + W I+ A + LQV R V++ L W++ + + L+
Sbjct: 791 DQIQNAAFMYPPNPWKEISHEAIDLINNLLQVKMRKRYSVDKTLSHPWLQDYQTWLD 847
>Hs5031689 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD and related
proteins
Length = 890
Score = 115 bits (289), Expect = 1e-25
Identities = 84/290 (28%), Positives = 140/290 (47%), Gaps = 30/290 (10%)
Query: 144 IVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKLNHPNIIR 203
++GSG FG V + R VA K + ++ ++++ E IL+ L+HP I+
Sbjct: 581 VLGSGQFGIVYGGKH--RKTGRDVAIKVID-KMRFPTKQESQLRNEVAILQNLHHPGIVN 637
Query: 204 IHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHSNG 263
+ + + V++ + + G L L+ +P E + ++ QIL+AL+ LH
Sbjct: 638 L-ECMFETPERVFVVMEKLHGDMLEMILSSEKSRLP--ERITKFMVTQILVALRNLHFKN 694
Query: 264 IVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKAD 323
IVH DLK +N+LL + EP +V L DFG A+ + + + R +VVGTP Y APEV
Sbjct: 695 IVHCDLKPENVLLASAEPFPQVKLCDFGFARIIGEKSFRR--SVVGTPAYLAPEV----- 747
Query: 324 RNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVRTGK 383
RS GY+ D+WS+GVI ++ L+G PF + I ++
Sbjct: 748 ---LRS-----------KGYNRSLDMWSVGVIIYVSLSGTFPF---NEDEDINDQIQNAA 790
Query: 384 LNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKHTSQLE 433
+ W I+ A + LQV R V+++L W++ + + L+
Sbjct: 791 FMYPPNPWREISGEAIDLINNLLQVKMRKRYSVDKSLSHPWLQDYQTWLD 840
>CE03584 [T] KOG0607 MAP kinase-interacting kinase and related
serine/threonine protein kinases
Length = 761
Score = 115 bits (289), Expect = 1e-25
Identities = 88/310 (28%), Positives = 142/310 (45%), Gaps = 58/310 (18%)
Query: 135 WDRWKIVPRIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINT-----AKTRMVKE 189
+D +K+ +GSG +G V + + K V YAVK+++ ++ R+++E
Sbjct: 197 FDYYKLTDEHLGSGAYGSVTTCKSI---------KSGVEYAVKIVDKQGETHSRKRILRE 247
Query: 190 ATILEKL-NHPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLII 248
I + +HPNI+++ D N Y+ + + GG L ++ + +E E+ +
Sbjct: 248 VNIFKTCKDHPNIVQLLDWFEDET-NFYLVMEKMRGGPLLQHILQRKYF---TEEEARRV 303
Query: 249 IYQILLALKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKE---------LSQN 299
I LALKF+H GI HRD+K +N+L P + V L D +A + LSQ
Sbjct: 304 TKDISLALKFMHDRGIAHRDVKPENVLCTDPNHVSPVKLCDLDLASQRPPQHERHPLSQV 363
Query: 300 TKE-RMHTVVGTPEYCAPEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHI 358
E + + VG+ E+ APEV D + D+ YD KCD WSLGVI +I
Sbjct: 364 ASEPDLASPVGSAEFMAPEV---VDAYV-----------GDSLKYDKKCDTWSLGVILYI 409
Query: 359 MLTGISPFYG---------------DGSEASIIKNVRTGKLNFTARQWIAITDSAKSFVK 403
ML G +PF G + + + ++ G F +W I++ AK V
Sbjct: 410 MLAGYAPFQGMCDDEDCGWSEGKPCEDCQQDLFHRIQDGYYEFPEEEWGMISEEAKDLVS 469
Query: 404 KCLQVSTFNR 413
L+ +R
Sbjct: 470 NLLKRDPVDR 479
>CE18058_1 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 416
Score = 115 bits (288), Expect = 1e-25
Identities = 76/272 (27%), Positives = 134/272 (48%), Gaps = 28/272 (10%)
Query: 174 YAVKVINTAKTRMVKEATILEKLN-HPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLA 232
YA + + +E +L+K+ + N++ +H + + +V I +L+SGG+LF ++
Sbjct: 107 YATSRRGVTRQNIEREVRVLQKIRGNSNVVELH-AVYETASDVIIVLELVSGGELFDHVC 165
Query: 233 KGDCLVPISETESLIIIYQILLALKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGI 292
+CL E E+ I QILLA++ LHS IVH D+K +N++L +++ + DFG+
Sbjct: 166 AKECL---DEVEAAAFIKQILLAVRHLHSLHIVHLDIKPENVML-KQRGDSQIKIIDFGL 221
Query: 293 AKELSQNTKERMHTVVGTPEYCAPEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSL 352
++E+ + +VGTPE+ APEV + D+W++
Sbjct: 222 SREIEPGAV--VKDMVGTPEFVAPEV-------------------VNYEALSPATDMWAV 260
Query: 353 GVITHIMLTGISPFYGDGSEASIIKNVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFN 412
GV+T+I+L+G SPF GD + + N+ + +F+ R + + AK F+ +
Sbjct: 261 GVVTYILLSGGSPFLGDNRDET-FSNITRVRYHFSDRYFKNTSKHAKDFIYRLFVRDVDQ 319
Query: 413 RCDVEEALHQVWVEKHTSQLERIYKKKVLQLS 444
R VEE L W+ I K + +S
Sbjct: 320 RATVEECLQHPWIRGPEGNAIDIRKASCITIS 351
>At3g56760 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 577
Score = 114 bits (286), Expect = 3e-25
Identities = 86/284 (30%), Positives = 140/284 (49%), Gaps = 30/284 (10%)
Query: 145 VGSGTFGHVLVAEKVDHNMKRQ-VAKKTVSYAVKVINTAKTRMVKEATILEKLN-HPNII 202
VG G FG+ A+ ++K Q VA K + + A + +E IL L H N++
Sbjct: 130 VGRGHFGYTCSAKGKKGSLKGQDVAVKVIPKSKMTTAIAIEDVRREVKILRALTGHKNLV 189
Query: 203 RIHQSCVDALGNVYIFQDLISGGDLFS-YLAKGDCLVPISETESLIIIYQILLALKFLHS 261
+ + + D NVYI +L GG+L L +G SE ++ ++ QIL + + H
Sbjct: 190 QFYDAFEDD-ENVYIVMELCQGGELLDKILQRGG---KYSEVDAKKVMIQILSVVAYCHL 245
Query: 262 NGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFK 321
G+VHRDLK +N L T + + + DFG++ + + ER++ +VG+ Y APEV
Sbjct: 246 QGVVHRDLKPENFLFTTKDESSPLKAIDFGLSDYVRPD--ERLNDIVGSAYYVAPEV--- 300
Query: 322 ADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVRT 381
++R+ Y ++ D+WS+GVI +I+L G PF+ SE+ I + V
Sbjct: 301 ----LHRT-------------YGTEADMWSIGVIAYILLCGSRPFWA-RSESGIFRAVLK 342
Query: 382 GKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWV 425
+ NF W +++ A FVK+ L R +AL W+
Sbjct: 343 AEPNFEEAPWPSLSPDAVDFVKRLLNKDYRKRLTAAQALCHPWL 386
>At3g23000 [T] KOG0583 Serine/threonine protein kinase
Length = 429
Score = 114 bits (286), Expect = 3e-25
Identities = 95/336 (28%), Positives = 160/336 (47%), Gaps = 45/336 (13%)
Query: 143 RIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKL-NHPNI 201
R +GSG+F V +A ++ + VA K + + + + R+++E + +L +HPNI
Sbjct: 29 RRLGSGSFAKVHLARSIESD--ELVAVKIIEKKKTIESGMEPRIIREIDAMRRLRHHPNI 86
Query: 202 IRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHS 261
++IH+ + +Y+ +L SGG+LFS + + L E+ + Q+ AL+F H
Sbjct: 87 LKIHE-VMATKSKIYLVMELASGGELFSKVLRRGRL---PESTARRYFQQLASALRFSHQ 142
Query: 262 NGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFK 321
+G+ HRD+K N+LL + + ++DFG++ +HT GTP Y APEV
Sbjct: 143 DGVAHRDVKPQNLLL---DEQGNLKVSDFGLSALPEHLQNGLLHTACGTPAYTAPEV--- 196
Query: 322 ADRNIYRSFSRTATLDPDNNGYD-SKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVR 380
SR GYD +K D WS GVI ++L G PF D + A++ + +
Sbjct: 197 --------ISR--------RGYDGAKADAWSCGVILFVLLVGDVPF-DDSNIAAMYRKIH 239
Query: 381 TGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEK--HTSQLER-IYK 437
F + W I+ AKS + + L + R +E + W +K TS+ R ++
Sbjct: 240 RRDYRFPS--W--ISKQAKSIIYQMLDPNPVTRMSIETVMKTNWFKKSLETSEFHRNVFD 295
Query: 438 KKVLQLSS-------DCIKIDENIDTFAVVKHKLPK 466
+V SS D I + +D + + K K
Sbjct: 296 SEVEMKSSVNSITAFDLISLSSGLDLSGLFEAKKKK 331
>At2g41140 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 576
Score = 114 bits (286), Expect = 3e-25
Identities = 93/326 (28%), Positives = 154/326 (46%), Gaps = 41/326 (12%)
Query: 104 IQLPNGAKFKFSAVKSETMS-QFMTGLRIKSEWDRWKIVPRIVGSGTFGHVLVAEKVDHN 162
+ +P G + + KS S QF + I E VG G FG+ A+ +
Sbjct: 97 VSIPEGKECEIGLDKSFGFSKQFASHYEIDGE----------VGRGHFGYTCSAKGKKGS 146
Query: 163 MKRQ-VAKKTVSYAVKVINTAKTRMVKEATILEKLN-HPNIIRIHQSCVDALGNVYIFQD 220
+K Q VA K + + A + +E +L L H N+++ + + D NVYI +
Sbjct: 147 LKGQEVAVKVIPKSKMTTAIAIEDVSREVKMLRALTGHKNLVQFYDAFEDD-ENVYIVME 205
Query: 221 LISGGDLFS-YLAKGDCLVPISETESLIIIYQILLALKFLHSNGIVHRDLKLDNILLHTP 279
L GG+L L +G SE ++ ++ QIL + + H G+VHRDLK +N L T
Sbjct: 206 LCKGGELLDKILQRGG---KYSEDDAKKVMVQILSVVAYCHLQGVVHRDLKPENFLFSTK 262
Query: 280 EPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKADRNIYRSFSRTATLDPD 339
+ + + DFG++ + + ER++ +VG+ Y APEV ++R+
Sbjct: 263 DETSPLKAIDFGLSDYVKPD--ERLNDIVGSAYYVAPEV-------LHRT---------- 303
Query: 340 NNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVRTGKLNFTARQWIAITDSAK 399
Y ++ D+WS+GVI +I+L G PF+ +E+ I + V + NF W +++ A
Sbjct: 304 ---YGTEADMWSIGVIAYILLCGSRPFWA-RTESGIFRAVLKAEPNFEEAPWPSLSPEAV 359
Query: 400 SFVKKCLQVSTFNRCDVEEALHQVWV 425
FVK+ L R +AL W+
Sbjct: 360 DFVKRLLNKDYRKRLTAAQALCHPWL 385
>At1g76040 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 534
Score = 114 bits (286), Expect = 3e-25
Identities = 84/282 (29%), Positives = 139/282 (48%), Gaps = 30/282 (10%)
Query: 145 VGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKLN-HPNIIR 203
+G G FG + + D + R+ A K++S + + +E IL+ L PNI+
Sbjct: 91 LGRGQFG--ITYKCTDKSNGREYACKSISKRKLIRRKDIEDVRREVMILQHLTGQPNIVE 148
Query: 204 IHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHSNG 263
+ D N+++ +L SGG+LF + K SE E+ I QI+ + H G
Sbjct: 149 FRGAYEDK-DNLHLVMELCSGGELFDRIIKKGSY---SEKEAANIFRQIVNVVHVCHFMG 204
Query: 264 IVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKAD 323
+VHRDLK +N LL + E + + DFG++ + + R +VG+ Y APEV
Sbjct: 205 VVHRDLKPENFLLVSNEEDSPIKATDFGLSVFIEEGKVYR--DIVGSAYYVAPEV----- 257
Query: 324 RNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVRTGK 383
++R+ Y + D+WS GV+ +I+L+G+ PF+G+ +E +I + + GK
Sbjct: 258 --LHRN-------------YGKEIDVWSAGVMLYILLSGVPPFWGE-TEKTIFEAILEGK 301
Query: 384 LNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWV 425
L+ W I++SAK ++K L R EAL W+
Sbjct: 302 LDLETSPWPTISESAKDLIRKMLIRDPKKRITAAEALEHPWM 343
>At1g12680 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 470
Score = 114 bits (286), Expect = 3e-25
Identities = 78/301 (25%), Positives = 141/301 (45%), Gaps = 40/301 (13%)
Query: 132 KSEWDRWKIVPRIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEAT 191
K++ D + R +G G FG V + + K +A K + + + +E
Sbjct: 100 KNKIDDDYVFGRNIGKGKFGSVRICKS---------RKNGTEFACKTLKKGEETVHREVE 150
Query: 192 ILEKLN-HPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIY 250
I++ L+ HP ++ +H + + ++ +L SGG L + K + SE + I
Sbjct: 151 IMQHLSGHPRVVTLH-AVYEESDCFHLVMELCSGGRLIDQMVK---VGRYSEQRAANIFK 206
Query: 251 QILLALKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGT 310
++L + + H G+VHRD+K +NILL K+ LADFG+A +++ + + + G+
Sbjct: 207 DLMLVINYCHEMGVVHRDIKPENILLTA---AGKIQLADFGLAMRIAKG--QTLSGLAGS 261
Query: 311 PEYCAPEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDG 370
P Y APEV + Y K D+WS GV+ + +L+G+ PF GD
Sbjct: 262 PAYVAPEVL--------------------SENYSEKVDVWSAGVLLYALLSGVLPFKGDS 301
Query: 371 SEASIIKNVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKHTS 430
+A I + ++ KL+F W +++ A+ + + L R +E L W+ +T
Sbjct: 302 LDA-IFEAIKNVKLDFNTGVWESVSKPARDLLARMLTREESARITADEVLRHPWILFYTD 360
Query: 431 Q 431
+
Sbjct: 361 R 361
>HsM4506035 [T] KOG0604 MAP kinase-activated protein kinase 2
Length = 471
Score = 114 bits (285), Expect = 3e-25
Identities = 91/312 (29%), Positives = 142/312 (45%), Gaps = 31/312 (9%)
Query: 145 VGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKLNHPNIIRI 204
+G+G G V V K + + + A K + K N + M+ HPNI++I
Sbjct: 28 LGAGISGPVRVCVK--KSTQERFALKILLDRPKARNEVRLHMMCAT-------HPNIVQI 78
Query: 205 HQSCVDAL---------GNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLA 255
+ +++ + I +++ GG+LF +++ +E ++ + QI LA
Sbjct: 79 IEVFANSVQFPHESSPRARLLIVMEMMEGGELFHRISQHR---HFTEKQASQVTKQIALA 135
Query: 256 LKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCA 315
L+ H I HRDLK +N+L V L DFG AK + Q + T TP Y A
Sbjct: 136 LRHCHLLNIAHRDLKPENLLFKDNSLDAPVKLCDFGFAK-IDQGD---LMTPQFTPYYVA 191
Query: 316 PEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASI 375
P+V +A R + S P Y+ CD+WSLGVI ++ML G PFY +I
Sbjct: 192 PQV-LEAQRRHQKEKSGIIPTSPTPYTYNKSCDLWSLGVIIYVMLCGYPPFYSKHHSRTI 250
Query: 376 IKNVR----TGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKHTSQ 431
K++R TG F +W I++ AK V+K L+V R +E L W+ T
Sbjct: 251 PKDMRRKIMTGSFEFPEEEWSQISEMAKDVVRKLLKVKPERRLTIEGVLDHPWLNS-TEA 309
Query: 432 LERIYKKKVLQL 443
L+ + L +
Sbjct: 310 LDNVLPSAQLMM 321
>Hs21237768 [T] KOG0604 MAP kinase-activated protein kinase 2
Length = 473
Score = 114 bits (285), Expect = 3e-25
Identities = 91/312 (29%), Positives = 142/312 (45%), Gaps = 31/312 (9%)
Query: 145 VGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKLNHPNIIRI 204
+G+G G V V K + + + A K + K N + M+ HPNI++I
Sbjct: 28 LGAGISGPVRVCVK--KSTQERFALKILLDRPKARNEVRLHMMCAT-------HPNIVQI 78
Query: 205 HQSCVDAL---------GNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLA 255
+ +++ + I +++ GG+LF +++ +E ++ + QI LA
Sbjct: 79 IEVFANSVQFPHESSPRARLLIVMEMMEGGELFHRISQHR---HFTEKQASQVTKQIALA 135
Query: 256 LKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCA 315
L+ H I HRDLK +N+L V L DFG AK + Q + T TP Y A
Sbjct: 136 LRHCHLLNIAHRDLKPENLLFKDNSLDAPVKLCDFGFAK-IDQGD---LMTPQFTPYYVA 191
Query: 316 PEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASI 375
P+V +A R + S P Y+ CD+WSLGVI ++ML G PFY +I
Sbjct: 192 PQV-LEAQRRHQKEKSGIIPTSPTPYTYNKSCDLWSLGVIIYVMLCGYPPFYSKHHSRTI 250
Query: 376 IKNVR----TGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKHTSQ 431
K++R TG F +W I++ AK V+K L+V R +E L W+ T
Sbjct: 251 PKDMRRKIMTGSFEFPEEEWSQISEMAKDVVRKLLKVKPEERLTIEGVLDHPWLNS-TEA 309
Query: 432 LERIYKKKVLQL 443
L+ + L +
Sbjct: 310 LDNVLPSAQLMM 321
>Hs21237765 [T] KOG0604 MAP kinase-activated protein kinase 2
Length = 471
Score = 114 bits (285), Expect = 3e-25
Identities = 91/312 (29%), Positives = 142/312 (45%), Gaps = 31/312 (9%)
Query: 145 VGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKLNHPNIIRI 204
+G+G G V V K + + + A K + K N + M+ HPNI++I
Sbjct: 28 LGAGISGPVRVCVK--KSTQERFALKILLDRPKARNEVRLHMMCAT-------HPNIVQI 78
Query: 205 HQSCVDAL---------GNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLA 255
+ +++ + I +++ GG+LF +++ +E ++ + QI LA
Sbjct: 79 IEVFANSVQFPHESSPRARLLIVMEMMEGGELFHRISQHR---HFTEKQASQVTKQIALA 135
Query: 256 LKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCA 315
L+ H I HRDLK +N+L V L DFG AK + Q + T TP Y A
Sbjct: 136 LRHCHLLNIAHRDLKPENLLFKDNSLDAPVKLCDFGFAK-IDQGD---LMTPQFTPYYVA 191
Query: 316 PEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASI 375
P+V +A R + S P Y+ CD+WSLGVI ++ML G PFY +I
Sbjct: 192 PQV-LEAQRRHQKEKSGIIPTSPTPYTYNKSCDLWSLGVIIYVMLCGYPPFYSKHHSRTI 250
Query: 376 IKNVR----TGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKHTSQ 431
K++R TG F +W I++ AK V+K L+V R +E L W+ T
Sbjct: 251 PKDMRRKIMTGSFEFPEEEWSQISEMAKDVVRKLLKVKPEERLTIEGVLDHPWLNS-TEA 309
Query: 432 LERIYKKKVLQL 443
L+ + L +
Sbjct: 310 LDNVLPSAQLMM 321
>Hs9994197 [T] KOG0607 MAP kinase-interacting kinase and related
serine/threonine protein kinases
Length = 414
Score = 113 bits (283), Expect = 6e-25
Identities = 79/278 (28%), Positives = 132/278 (47%), Gaps = 43/278 (15%)
Query: 174 YAVKVINTA----KTRMVKEATILEKLN-HPNIIRIHQSCVDALGNVYIFQDLISGGDLF 228
YAVK+I ++R+ +E +L + H N++ + + + Y+ + + GG +
Sbjct: 110 YAVKIIEKQPGHIRSRVFREVEMLYQCQGHRNVLELIEFFEEE-DRFYLVFEKMRGGSIL 168
Query: 229 SYLAKGDCLVPISETESLIIIYQILLALKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLA 288
S++ K +E E+ +++ + AL FLH+ GI HRDLK +NIL P + V +
Sbjct: 169 SHIHKRR---HFNELEASVVVQDVASALDFLHNKGIAHRDLKPENILCEHPNQVSPVKIC 225
Query: 289 DFGIAKELSQN------TKERMHTVVGTPEYCAPEVGFKADRNIYRSFSRTATLDPDNNG 342
DF + + N + + T G+ EY APE + +FS A++
Sbjct: 226 DFDLGSGIKLNGDCSPISTPELLTPCGSAEYMAPE--------LVEAFSEEASI------ 271
Query: 343 YDSKCDIWSLGVITHIMLTGISPFYG--------DGSEA------SIIKNVRTGKLNFTA 388
YD +CD+WSLGVI +I+L+G PF G D EA + ++++ GK F
Sbjct: 272 YDKRCDLWSLGVILYILLSGYPPFVGRCGSDCGWDRGEACPACQNMLFESIQEGKYEFPD 331
Query: 389 RQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVE 426
+ W I+ +AK + K L R + L WV+
Sbjct: 332 KDWAHISCAAKDLISKLLVRDAKQRLSAAQVLQHPWVQ 369
>Hs4758192 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 414
Score = 113 bits (283), Expect = 6e-25
Identities = 84/323 (26%), Positives = 155/323 (47%), Gaps = 29/323 (8%)
Query: 122 MSQFMTGLRIKSEWDRWKIVP-RIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVIN 180
+++ +R + D + + P R +G G F V K D ++ A K + K
Sbjct: 43 LTEIRAVVRTEPFQDGYSLCPGRELGRGKFAVVRKCIKKDSG--KEFAAKFMRKRRKG-Q 99
Query: 181 TAKTRMVKEATILEKL-NHPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVP 239
+ ++ E +LE ++P +I +H+ + + + + +GG++F D
Sbjct: 100 DCRMEIIHEIAVLELAQDNPWVINLHE-VYETASEMILVLEYAAGGEIFDQCV-ADREEA 157
Query: 240 ISETESLIIIYQILLALKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQN 299
E + ++ QIL + FLH+ +VH DLK NILL + P + + DFG+++ L +
Sbjct: 158 FKEKDVQRLMRQILEGVHFLHTRDVVHLDLKPQNILLTSESPLGDIKIVDFGLSRILKNS 217
Query: 300 TKERMHTVVGTPEYCAPEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIM 359
E + ++GTPEY APE+ + DP D+WS+GV+T++M
Sbjct: 218 --EELREIMGTPEYVAPEI---------------LSYDP----ISMATDMWSIGVLTYVM 256
Query: 360 LTGISPFYGDGSEASIIKNVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEA 419
LTGISPF G+ + + + N+ L+++ ++ +++SA F++ L +R EE
Sbjct: 257 LTGISPFLGNDKQETFL-NISQMNLSYSEEEFDVLSESAVDFIRTLLVKKPEDRATAEEC 315
Query: 420 LHQVWVEKHTSQLERIYKKKVLQ 442
L W+ + + Q +K L+
Sbjct: 316 LKHPWLTQSSIQEPSFRMEKALE 338
>Hs14589904 [T] KOG0604 MAP kinase-activated protein kinase 2
Length = 400
Score = 113 bits (283), Expect = 6e-25
Identities = 91/318 (28%), Positives = 146/318 (45%), Gaps = 53/318 (16%)
Query: 127 TGLRIKSEW--DRWKIVPRIVGSGTFGHVLVAEKVDHNMKRQVAKKTVS--YAVKVINTA 182
+GL+IK D +K+ +++G G G VL Q+ K +A+K++
Sbjct: 50 SGLQIKKNAIIDDYKVTSQVLGLGINGKVL-----------QIFNKRTQEKFALKMLQDC 98
Query: 183 KTRMVKEATILEKLNHPNIIRIHQSCVDALGNVY-------IFQDLISGGDLFSYLA-KG 234
+ P+I+RI VD N+Y I + + GG+LFS + +G
Sbjct: 99 PKARREVELHWRASQCPDIVRI----VDVYENLYAGRKCLLIVMECLDGGELFSRIQDRG 154
Query: 235 DCLVPISETESLIIIYQILLALKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAK 294
D +E E+ I+ I A+++LHS I HRD+K +N+L + P + L DFG AK
Sbjct: 155 D--QAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAK 212
Query: 295 ELSQNTKERMHTVVGTPEYCAPEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGV 354
E + + + T TP Y APEV L P+ YD CD+WSLGV
Sbjct: 213 ETTSHNS--LTTPCYTPYYVAPEV-----------------LGPEK--YDKSCDMWSLGV 251
Query: 355 ITHIMLTGISPFYGDGSEA---SIIKNVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTF 411
I +I+L G PFY + A + +R G+ F +W +++ K ++ L+
Sbjct: 252 IMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPT 311
Query: 412 NRCDVEEALHQVWVEKHT 429
R + E ++ W+ + T
Sbjct: 312 QRMTITEFMNHPWIMQST 329
>Hs10863901 [T] KOG0604 MAP kinase-activated protein kinase 2
Length = 370
Score = 113 bits (283), Expect = 6e-25
Identities = 91/318 (28%), Positives = 146/318 (45%), Gaps = 53/318 (16%)
Query: 127 TGLRIKSEW--DRWKIVPRIVGSGTFGHVLVAEKVDHNMKRQVAKKTVS--YAVKVINTA 182
+GL+IK D +K+ +++G G G VL Q+ K +A+K++
Sbjct: 50 SGLQIKKNAIIDDYKVTSQVLGLGINGKVL-----------QIFNKRTQEKFALKMLQDC 98
Query: 183 KTRMVKEATILEKLNHPNIIRIHQSCVDALGNVY-------IFQDLISGGDLFSYLA-KG 234
+ P+I+RI VD N+Y I + + GG+LFS + +G
Sbjct: 99 PKARREVELHWRASQCPHIVRI----VDVYENLYAGRKCLLIVMECLDGGELFSRIQDRG 154
Query: 235 DCLVPISETESLIIIYQILLALKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAK 294
D +E E+ I+ I A+++LHS I HRD+K +N+L + P + L DFG AK
Sbjct: 155 D--QAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAK 212
Query: 295 ELSQNTKERMHTVVGTPEYCAPEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGV 354
E + + + T TP Y APEV L P+ YD CD+WSLGV
Sbjct: 213 ETTSHNS--LTTPCYTPYYVAPEV-----------------LGPEK--YDKSCDMWSLGV 251
Query: 355 ITHIMLTGISPFYGDGSEA---SIIKNVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTF 411
I +I+L G PFY + A + +R G+ F +W +++ K ++ L+
Sbjct: 252 IMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPT 311
Query: 412 NRCDVEEALHQVWVEKHT 429
R + E ++ W+ + T
Sbjct: 312 QRMTITEFMNHPWIMQST 329
>7296128 [T] KOG0583 Serine/threonine protein kinase
Length = 550
Score = 113 bits (283), Expect = 6e-25
Identities = 77/240 (32%), Positives = 130/240 (54%), Gaps = 35/240 (14%)
Query: 145 VGSGTFGHVLVAEKVDHNMKR-QVAKKTVSYAVKVINTAKTRMVK-EATILEKLNHPNII 202
+G G F V +A H + R +VA K V ++ RM+ E LE ++HPNI+
Sbjct: 50 IGRGNFSKVKLAV---HQLTRDKVAIKVVDLDRAGLDAKALRMLSSEIATLECVHHPNIL 106
Query: 203 RIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHSN 262
R+ + V+ LG VY+ + I GG+L++++ +G P+ E + ++ Q+LLA+K +HS
Sbjct: 107 RLFE-VVETLGRVYLVTEWIRGGELYNHITQGG---PLREIHAAPLLKQLLLAVKHMHSL 162
Query: 263 GIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNT--KERMHTVVGTPEYCAPEVGF 320
G VHRD+K +N+LL + + ++ LADFG + +L T +++ T G+P Y APE
Sbjct: 163 GYVHRDIKAENVLLLSED---RLKLADFGFSTQLINGTGANQKLDTFCGSPPYAAPE--- 216
Query: 321 KADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYG---DGSEASIIK 377
L D++ + D+W+LG++ + M+ G PF G +A+I+K
Sbjct: 217 ---------------LFSDDHYIGAPVDVWALGILLYFMVVGNMPFRAPTIPGLKAAILK 261
>SPAC22E12.14c [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 646
Score = 113 bits (282), Expect = 7e-25
Identities = 96/286 (33%), Positives = 137/286 (47%), Gaps = 41/286 (14%)
Query: 143 RIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKLN---HP 199
+++G GTFG V + K D +R A K +S V V V E IL + + P
Sbjct: 270 KLIGKGTFGQVYLVRKKD--TERVYAMKVLSKKVIVRRKEVAHTVGERDILVQTSAADSP 327
Query: 200 NIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFL 259
I+ + S ++Y+ D ++GG+LF +L K V E + I ++LLAL+ L
Sbjct: 328 FIVALRFS-FQTPKDLYLVTDYMAGGELFWHLQKS---VRFPEERAKFYIAELLLALQAL 383
Query: 260 HSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAK-ELSQNTKERMHTVVGTPEYCAPEV 318
H GIV+RDLK +NILL + L DFG++K LS T R T GT +Y APEV
Sbjct: 384 HKRGIVYRDLKPENILLDVQG---HIALCDFGLSKANLSVGTTTR--TFCGTTDYLAPEV 438
Query: 319 GFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKN 378
D GYD D WSLGV+ + M G SPFY D ++ + KN
Sbjct: 439 IL------------------DEAGYDMMVDFWSLGVLLYEMTCGWSPFYADNTQ-QLYKN 479
Query: 379 VRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRC----DVEEAL 420
+ GK+ F ++ A+ +K L + +R DVEE +
Sbjct: 480 IVFGKVRFPRG---LLSVEARDLIKLLLNRNPKHRLGAHGDVEEVM 522
>Hs4505785 [G] KOG0599 Phosphorylase kinase gamma subunit
Length = 406
Score = 113 bits (282), Expect = 7e-25
Identities = 79/267 (29%), Positives = 136/267 (50%), Gaps = 36/267 (13%)
Query: 174 YAVKVINTAKTRM-------VKEAT------ILEKLNHPNIIRIHQSCVDALGNVYIFQD 220
+AVK++ R+ V+EAT + + HP+II + S ++ +++ D
Sbjct: 50 FAVKIMEVTAERLSPEQLEEVREATRRETHILRQVAGHPHIITLIDS-YESSSFMFLVFD 108
Query: 221 LISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHSNGIVHRDLKLDNILLHTPE 280
L+ G+LF YL + V +SE E+ I+ +L A+ FLH+N IVHRDLK +NILL +
Sbjct: 109 LMRKGELFDYLTEK---VALSEKETRSIMRSLLEAVSFLHANNIVHRDLKPENILL---D 162
Query: 281 PCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKADRNIYRSFSRTATLDPDN 340
++ L+DFG + L E++ + GTP Y APE+ ++D +
Sbjct: 163 DNMQIRLSDFGFSCHLEPG--EKLRELCGTPGYLAPEI-------------LKCSMDETH 207
Query: 341 NGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVRTGKLNFTARQWIAITDSAKS 400
GY + D+W+ GVI +L G PF+ + +++ + G+ F++ +W + + K
Sbjct: 208 PGYGKEVDLWACGVILFTLLAGSPPFW-HRRQILMLRMIMEGQYQFSSPEWDDRSSTVKD 266
Query: 401 FVKKCLQVSTFNRCDVEEALHQVWVEK 427
+ + LQV R E+AL + E+
Sbjct: 267 LISRLLQVDPEARLTAEQALQHPFFER 293
>7299437 [R] KOG0586 Serine/threonine protein kinase
Length = 604
Score = 113 bits (282), Expect = 7e-25
Identities = 83/289 (28%), Positives = 149/289 (50%), Gaps = 38/289 (13%)
Query: 138 WKIVPRIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINT-AKTRMVKEATILEKL 196
+KI+ + +G G F V +A + R+VA K + +NT A+ ++ +E I++KL
Sbjct: 63 YKII-KTLGKGNFAKVKLAIHLPTG--REVAIKLIDKTA--LNTIARQKLYREVNIMKKL 117
Query: 197 NHPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLAL 256
NHPNI+R+ Q +++ +Y+ + +SGG+LF+YL K + E ++ ++ Q++ A+
Sbjct: 118 NHPNIVRLLQ-VIESERTLYLVMEYVSGGELFNYLVKNGRM---RERDARVLFRQLVSAI 173
Query: 257 KFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAP 316
++ HS IVHRDLK +N+LL + K+ +ADFG + K + T G+P Y AP
Sbjct: 174 EYCHSKSIVHRDLKAENLLL---DQQMKLKIADFGFSTTF--EPKAPLETFCGSPPYAAP 228
Query: 317 EVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASII 376
E+ F+ + +S + D WSLGV+ + +++G PF G +
Sbjct: 229 EL-FRG-----KKYS------------GPEVDSWSLGVVLYTLVSGSLPFDGTN-----L 265
Query: 377 KNVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWV 425
K +R L R ++ +S ++K L ++ R + + W+
Sbjct: 266 KELRDRVLRGKYRVPYYVSIECESLIRKFLVLNPTQRTSLSAVMADRWI 314
>At4g36070 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 536
Score = 112 bits (280), Expect = 1e-24
Identities = 84/295 (28%), Positives = 137/295 (45%), Gaps = 31/295 (10%)
Query: 134 EWDRWKIVPRIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATIL 193
++D + +++G G FG VA D+N +VA K + A + +E IL
Sbjct: 66 DFDNRYTIGKLLGHGQFGFTYVA--TDNNNGNRVAVKRIDKAKMTQPIEVEDVKREVKIL 123
Query: 194 EKLN-HPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQI 252
+ L H N++ H + D +YI +L GG+L + +E ++ +++ Q+
Sbjct: 124 QALGGHENVVGFHNAFEDKT-YIYIVMELCDGGELLDRILANR----YTEKDAAVVVRQM 178
Query: 253 LLALKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPE 312
L H G+VHRD+K +N L + E + + DFG++ + K +VG+
Sbjct: 179 LKVAAECHLRGLVHRDMKPENFLFKSTEEGSSLKATDFGLSDFIKPGVK--FQDIVGSAY 236
Query: 313 YCAPEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSE 372
Y APEV + +G +S D+WS+GVIT+I+L G PF+ D ++
Sbjct: 237 YVAPEVLKR------------------RSGPES--DVWSIGVITYILLCGRRPFW-DKTQ 275
Query: 373 ASIIKNVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEK 427
I V K +F W I++ AK FVKK L R +AL WV++
Sbjct: 276 DGIFNEVMRKKPDFREVPWPTISNGAKDFVKKLLVKEPRARLTAAQALSHSWVKE 330
>7303019 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 913
Score = 112 bits (280), Expect = 1e-24
Identities = 79/342 (23%), Positives = 168/342 (49%), Gaps = 34/342 (9%)
Query: 87 EQVLSRDVPYLLSNQDVIQLPNGAKFKFSAVKSETMSQFMTGLRIKSEW-DRWKIVPRIV 145
E + R P S +++Q+ N + S+ S+ Q ++ ++ R++I+ +
Sbjct: 228 ENIHGRSAPGQAS--ELVQITNTPQRSTSSDASDRFGQATVSVQSGGDFKSRFEIIEEL- 284
Query: 146 GSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKLNHPNIIRIH 205
G G FG +V + + Q+ V +K + + ++++E +I+ L HP ++++
Sbjct: 285 GKGRFG--IVYKVQERGQPEQLLAAKVIKCIK--SQDRQKVLEEISIMRALQHPKLLQLA 340
Query: 206 QSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHSNGIV 265
S ++ + + + I+GG+LF + D ++E + ++ + Q+ + ++H +V
Sbjct: 341 AS-FESPREIVMVMEYITGGELFERVVADD--FTLTEMDCILFLRQVCDGVAYMHGQSVV 397
Query: 266 HRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKADRN 325
H DLK +NI+ HT ++ + DFG+A+ L +TK + + GTPE+ PE+
Sbjct: 398 HLDLKPENIMCHT-RTSHQIKIIDFGLAQRL--DTKAPVRVLFGTPEFIPPEI------- 447
Query: 326 IYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVRTGKLN 385
+ + G+ S D+WS+GVI +++L+G+SPF GD ++ N+ +
Sbjct: 448 ----------ISYEPIGFQS--DMWSVGVICYVLLSGLSPFMGD-TDVETFSNITRADYD 494
Query: 386 FTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEK 427
+ + ++ AK F+ + L +R ++ L W+ +
Sbjct: 495 YDDEAFDCVSQEAKDFISQLLVHRKEDRLTAQQCLASKWLSQ 536
>At2g38910 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 583
Score = 111 bits (278), Expect = 2e-24
Identities = 87/302 (28%), Positives = 139/302 (45%), Gaps = 30/302 (9%)
Query: 141 VPRIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKLN-HP 199
V R +G G FG + VD ++ A KT++ + +E I+ L+ HP
Sbjct: 136 VGRKLGQGQFGTTFLC--VDKKTGKEFACKTIAKRKLTTPEDVEDVRREIQIMHHLSGHP 193
Query: 200 NIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFL 259
N+I+I + DA+ V++ ++ +GG+LF + + E II ++ A
Sbjct: 194 NVIQIVGAYEDAVA-VHVVMEICAGGELFDRIIQRGHYTEKKAAELARIIVGVIEAC--- 249
Query: 260 HSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVG 319
HS G++HRDLK +N L + + + DFG++ E VVG+P Y APEV
Sbjct: 250 HSLGVMHRDLKPENFLFVSGDEEAALKTIDFGLSVFFKPG--ETFTDVVGSPYYVAPEVL 307
Query: 320 FKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNV 379
K Y +CD+WS GVI +I+L+G+ PF+ D +E I + V
Sbjct: 308 RKH--------------------YSHECDVWSAGVIIYILLSGVPPFW-DETEQGIFEQV 346
Query: 380 RTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKHTSQLERIYKKK 439
G L+F + W ++++SAK V++ L R E L W L++
Sbjct: 347 LKGDLDFISEPWPSVSESAKDLVRRMLIRDPKKRMTTHEVLCHPWARVDGVALDKPLDSA 406
Query: 440 VL 441
VL
Sbjct: 407 VL 408
>At1g18890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 545
Score = 111 bits (278), Expect = 2e-24
Identities = 92/336 (27%), Positives = 155/336 (45%), Gaps = 57/336 (16%)
Query: 140 IVPRIVGSGTFGHV-LVAEKVDHNMK--RQVAKKTVSYAVKVINTAKTRMVKEATILEKL 196
I+ R +G G FG L ++ H + ++K+ + AV + + + E I+ L
Sbjct: 64 ILGRELGRGEFGITYLCTDRETHEALACKSISKRKLRTAVDIEDVRR-----EVAIMSTL 118
Query: 197 -NHPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYL-AKGDCLVPISETESLIIIYQILL 254
HPN++++ S D NV++ +L GG+LF + A+G +E + + I
Sbjct: 119 PEHPNVVKLKASYEDN-ENVHLVMELCEGGELFDRIVARGH----YTERAAAAVARTIAE 173
Query: 255 ALKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYC 314
+ HSNG++HRDLK +N L + + + DFG++ ++ +VG+P Y
Sbjct: 174 VVMMCHSNGVMHRDLKPENFLFANKKENSPLKAIDFGLSVFFKPG--DKFTEIVGSPYYM 231
Query: 315 APEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEAS 374
APEV K D Y D+WS GVI +I+L G+ PF+ + +E
Sbjct: 232 APEV-LKRD-------------------YGPGVDVWSAGVIIYILLCGVPPFWAE-TEQG 270
Query: 375 IIKNVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVE-------- 426
+ + G L+F W I++SAKS VK+ L R ++ L W++
Sbjct: 271 VALAILRGVLDFKRDPWPQISESAKSLVKQMLDPDPTKRLTAQQVLAHPWIQNAKKAPNV 330
Query: 427 ----------KHTSQLERIYKKKVLQLSSDCIKIDE 452
K S + R +KKKVL++ ++ + I E
Sbjct: 331 PLGDIVRSRLKQFSMMNR-FKKKVLRVIAEHLSIQE 365
>CE04603 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 371
Score = 110 bits (275), Expect = 5e-24
Identities = 88/289 (30%), Positives = 145/289 (49%), Gaps = 44/289 (15%)
Query: 145 VGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMV-KEATILEKLNHPNIIR 203
+G GTFG V +A D A K ++ +V++ +T+ V E +L +L HP I++
Sbjct: 69 IGKGTFGRVELAR--DKITGAHYALKVLNIR-RVVDMRQTQHVHNEKRVLLQLKHPFIVK 125
Query: 204 IHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHSNG 263
++ S D+ ++Y+ + + GG++FSYL S + + +I+ AL+++HS G
Sbjct: 126 MYASEKDS-NHLYMIMEFVPGGEMFSYLRASRSF---SNSMARFYASEIVCALEYIHSLG 181
Query: 264 IVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKAD 323
IV+RDLK +N++L + +ADFG AKEL ++R +T+ GTP+Y APE
Sbjct: 182 IVYRDLKPENLMLSKE---GHIKMADFGFAKEL----RDRTYTICGTPDYLAPE------ 228
Query: 324 RNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVRTGK 383
S +RT G++ D W+LG++ + M+ G PF G + + I + K
Sbjct: 229 -----SLART--------GHNKGVDWWALGILIYEMMVGKPPFRGK-TTSEIYDAIIEHK 274
Query: 384 LNFTARQWIAITDSAKSFVKKCLQVSTFNRC-----DVEEALHQVWVEK 427
L F + +AK VKK L+V R ++ W EK
Sbjct: 275 LKFPR----SFNLAAKDLVKKLLEVDRTQRIGCMKNGTQDVKDHKWFEK 319
>At2g30360 [T] KOG0583 Serine/threonine protein kinase
Length = 435
Score = 110 bits (275), Expect = 5e-24
Identities = 77/285 (27%), Positives = 142/285 (49%), Gaps = 36/285 (12%)
Query: 143 RIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVK-EATILEKLNHPNI 201
+++G G F V A D + VA K ++ + N A +K E +I+ +L+HPNI
Sbjct: 25 KLLGCGAFAKVFHAR--DRRTGQSVAVKILNKKKLLTNPALANNIKREISIMRRLSHPNI 82
Query: 202 IRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHS 261
+++H+ + ++ + + GG+LF+ ++K L SE S Q++ A+ + H+
Sbjct: 83 VKLHE-VMATKSKIFFAMEFVKGGELFNKISKHGRL---SEDLSRRYFQQLISAVGYCHA 138
Query: 262 NGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKE-RMHTVVGTPEYCAPEVGF 320
G+ HRDLK +N+L+ + + ++DFG++ Q + +HT+ GTP Y APE+
Sbjct: 139 RGVYHRDLKPENLLI---DENGNLKVSDFGLSALTDQIRPDGLLHTLCGTPAYVAPEILS 195
Query: 321 KADRNIYRSFSRTATLDPDNNGYD-SKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNV 379
K GY+ +K D+WS G++ +++ G PF D + ++ K +
Sbjct: 196 K-------------------KGYEGAKVDVWSCGIVLFVLVAGYLPF-NDPNVMNMYKKI 235
Query: 380 RTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVW 424
G+ F +W ++ K FV + L ++ R ++E L W
Sbjct: 236 YKGEYRFP--RW--MSPDLKRFVSRLLDINPETRITIDEILKDPW 276
>7304283 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 7175
Score = 110 bits (275), Expect = 5e-24
Identities = 86/331 (25%), Positives = 156/331 (46%), Gaps = 41/331 (12%)
Query: 132 KSEWDRWKIVPRIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVI----NTAKTRMV 187
+S +DR+ I+ I G+G FG V H + + +A K I + K +
Sbjct: 6132 QSVYDRYDILEEI-GTGAFGVV-------HRCRERSTGNI--FAAKFIPVSHSVEKDLIR 6181
Query: 188 KEATILEKLNHPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLI 247
+E I+ +L+H +I +H + D + + + +SGG+LF + ++ +E E +
Sbjct: 6182 REIDIMNQLHHQKLINLHDAFEDD-DEMILILEFLSGGELFERITAEGYVM--TEAEVIN 6238
Query: 248 IIYQILLALKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTV 307
+ QI ++ +H I+H D+K +NI+ T T V L DFG+A L N ++ T
Sbjct: 6239 YMRQICEGIRHMHEQNIIHLDIKPENIMCQT-RSSTNVKLIDFGLATRLDPNEVVKITT- 6296
Query: 308 VGTPEYCAPEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFY 367
GT E+ APE+ + Y D+W+ GV+++++L+G+SPF
Sbjct: 6297 -GTAEFAAPEIVNREPVGFYT-------------------DMWATGVLSYVLLSGLSPFA 6336
Query: 368 GDGSEASIIKNVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVE- 426
GD ++ +KNV+ +F + I++ AK F++K L + R E L W+
Sbjct: 6337 GD-NDVQTLKNVKACDWDFDVESFKYISEEAKDFIRKLLVRNKEKRMTAHECLLHPWLTG 6395
Query: 427 KHTSQLERIYKKKVLQLSSDCIKIDENIDTF 457
H++ + I + + L + E+ + F
Sbjct: 6396 DHSAMKQEINRDRYLAYREKLRRKYEDFERF 6426
>7300413 [T] KOG0583 Serine/threonine protein kinase
Length = 302
Score = 110 bits (274), Expect = 6e-24
Identities = 88/285 (30%), Positives = 129/285 (44%), Gaps = 31/285 (10%)
Query: 145 VGSGTFGHVLVAEKVD-HNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKLNHPNIIR 203
+G G++ V+ A D H +A K + A + +E IL K++H NII+
Sbjct: 34 IGEGSYATVITAGYADDHGHGVHLACKIIDKAKAPTDFVNKFFPRELEILTKIDHSNIIQ 93
Query: 204 IHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHSNG 263
IH S + ++IF GDL S++ + PI E +S I +Q+ ALK+LH+
Sbjct: 94 IH-SILQRGPKIFIFMRYAENGDLLSHIKRSG---PIDEKQSKIWFFQMSKALKYLHNLD 149
Query: 264 IVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERM--HTVVGTPEYCAPEVGFK 321
I HRDLK +NILL + LADFG A+ + M T G+ Y APEV
Sbjct: 150 IAHRDLKCENILL---SKRLNIKLADFGFARYCRDDNGREMKSETYCGSAAYAAPEV--- 203
Query: 322 ADRNIYRSFSRTATLDPDNNGYDSK-CDIWSLGVITHIMLTGISPFYGDGSEASIIKNVR 380
YD K D WSLGVI IM+ PF D + ++++ R
Sbjct: 204 ----------------VCGRPYDPKLADAWSLGVILFIMMNAKMPF-DDSNLTKLLEDQR 246
Query: 381 TGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWV 425
K F + I+ AK+ V L+ R ++ E L+ W+
Sbjct: 247 NRKFAFRRKLQETISAQAKATVSVLLEPEAHARWNLREILNCAWL 291
>Hs4826948 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 358
Score = 109 bits (272), Expect = 1e-23
Identities = 87/270 (32%), Positives = 132/270 (48%), Gaps = 39/270 (14%)
Query: 145 VGSGTFGHV-LVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKLNHPNIIR 203
VG+GTFG V LV EK K A K +S + + + E ++L++++HP +IR
Sbjct: 55 VGTGTFGRVHLVKEKT---AKHFFALKVMSIPDVIRLKQEQHVHNEKSVLKEVSHPFLIR 111
Query: 204 IHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHSNG 263
+ + D +Y+ + + GG+LFSYL S T L +I+ A+++LHS
Sbjct: 112 LFWTWHDERF-LYMLMEYVPGGELFSYLRNRG---RFSSTTGLFYSAEIICAIEYLHSKE 167
Query: 264 IVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKAD 323
IV+RDLK +NILL + + L DFG AK+L +R T+ GTPEY APEV
Sbjct: 168 IVYRDLKPENILL---DRDGHIKLTDFGFAKKL----VDRTWTLCGTPEYLAPEV----- 215
Query: 324 RNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVRTGK 383
+ G+ D W+LG++ ML+G PF+ D + I + + GK
Sbjct: 216 --------------IQSKGHGRAVDWWALGILIFEMLSGFPPFF-DDNPFGIYQKILAGK 260
Query: 384 LNFTARQWIAITDSAKSFVKKCLQVSTFNR 413
++F + K +KK L V R
Sbjct: 261 IDFPRH----LDFHVKDLIKKLLVVDRTRR 286
>Hs20143922 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 27118
Score = 109 bits (272), Expect = 1e-23
Identities = 89/300 (29%), Positives = 145/300 (47%), Gaps = 37/300 (12%)
Query: 145 VGSGTFGHVLVAEKVDHNMKRQVAKKT-VSYAVKVINTAKTRMVKEATILEKLNHPNIIR 203
+G G FG V H +KKT ++ VKV T + + KE +IL H NI+
Sbjct: 24952 LGRGEFGIV-------HRCVETSSKKTYMAKFVKVKGTDQVLVKKEISILNIARHRNILH 25004
Query: 204 IHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHSNG 263
+H+S V IF+ ISG D+F + ++E E + ++Q+ AL+FLHS+
Sbjct: 25005 LHESFESMEELVMIFE-FISGLDIFERI--NTSAFELNEREIVSYVHQVCEALQFLHSHN 25061
Query: 264 IVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKAD 323
I H D++ +NI+ T T + + +FG A++L R+ + PEY APEV
Sbjct: 25062 IGHFDIRPENIIYQTRRSST-IKIIEFGQARQLKPGDNFRL--LFTAPEYYAPEVH---- 25114
Query: 324 RNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVRTGK 383
TAT D+WSLG + +++L+GI+PF + ++ II+N+ +
Sbjct: 25115 ---QHDVVSTAT------------DMWSLGTLVYVLLSGINPFLAETNQ-QIIENIMNAE 25158
Query: 384 LNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKHTSQLERIYKKKVLQL 443
F + I+ A FV + L +R EAL W+++ ++ER+ K + L
Sbjct: 25159 YTFDEEAFKEISIEAMDFVDRLLVKERKSRMTASEALQHPWLKQ---KIERVSTKVIRTL 25215
>Hs20143918 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 27051
Score = 109 bits (272), Expect = 1e-23
Identities = 89/300 (29%), Positives = 145/300 (47%), Gaps = 37/300 (12%)
Query: 145 VGSGTFGHVLVAEKVDHNMKRQVAKKT-VSYAVKVINTAKTRMVKEATILEKLNHPNIIR 203
+G G FG V H +KKT ++ VKV T + + KE +IL H NI+
Sbjct: 24885 LGRGEFGIV-------HRCVETSSKKTYMAKFVKVKGTDQVLVKKEISILNIARHRNILH 24937
Query: 204 IHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHSNG 263
+H+S V IF+ ISG D+F + ++E E + ++Q+ AL+FLHS+
Sbjct: 24938 LHESFESMEELVMIFE-FISGLDIFERI--NTSAFELNEREIVSYVHQVCEALQFLHSHN 24994
Query: 264 IVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKAD 323
I H D++ +NI+ T T + + +FG A++L R+ + PEY APEV
Sbjct: 24995 IGHFDIRPENIIYQTRRSST-IKIIEFGQARQLKPGDNFRL--LFTAPEYYAPEVH---- 25047
Query: 324 RNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVRTGK 383
TAT D+WSLG + +++L+GI+PF + ++ II+N+ +
Sbjct: 25048 ---QHDVVSTAT------------DMWSLGTLVYVLLSGINPFLAETNQ-QIIENIMNAE 25091
Query: 384 LNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKHTSQLERIYKKKVLQL 443
F + I+ A FV + L +R EAL W+++ ++ER+ K + L
Sbjct: 25092 YTFDEEAFKEISIEAMDFVDRLLVKERKSRMTASEALQHPWLKQ---KIERVSTKVIRTL 25148
>Hs20143914 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 26926
Score = 109 bits (272), Expect = 1e-23
Identities = 89/300 (29%), Positives = 145/300 (47%), Gaps = 37/300 (12%)
Query: 145 VGSGTFGHVLVAEKVDHNMKRQVAKKT-VSYAVKVINTAKTRMVKEATILEKLNHPNIIR 203
+G G FG V H +KKT ++ VKV T + + KE +IL H NI+
Sbjct: 24760 LGRGEFGIV-------HRCVETSSKKTYMAKFVKVKGTDQVLVKKEISILNIARHRNILH 24812
Query: 204 IHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHSNG 263
+H+S V IF+ ISG D+F + ++E E + ++Q+ AL+FLHS+
Sbjct: 24813 LHESFESMEELVMIFE-FISGLDIFERI--NTSAFELNEREIVSYVHQVCEALQFLHSHN 24869
Query: 264 IVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKAD 323
I H D++ +NI+ T T + + +FG A++L R+ + PEY APEV
Sbjct: 24870 IGHFDIRPENIIYQTRRSST-IKIIEFGQARQLKPGDNFRL--LFTAPEYYAPEVH---- 24922
Query: 324 RNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVRTGK 383
TAT D+WSLG + +++L+GI+PF + ++ II+N+ +
Sbjct: 24923 ---QHDVVSTAT------------DMWSLGTLVYVLLSGINPFLAETNQ-QIIENIMNAE 24966
Query: 384 LNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKHTSQLERIYKKKVLQL 443
F + I+ A FV + L +R EAL W+++ ++ER+ K + L
Sbjct: 24967 YTFDEEAFKEISIEAMDFVDRLLVKERKSRMTASEALQHPWLKQ---KIERVSTKVIRTL 25023
>Hs19747267 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 34350
Score = 109 bits (272), Expect = 1e-23
Identities = 89/300 (29%), Positives = 145/300 (47%), Gaps = 37/300 (12%)
Query: 145 VGSGTFGHVLVAEKVDHNMKRQVAKKT-VSYAVKVINTAKTRMVKEATILEKLNHPNIIR 203
+G G FG V H +KKT ++ VKV T + + KE +IL H NI+
Sbjct: 32184 LGRGEFGIV-------HRCVETSSKKTYMAKFVKVKGTDQVLVKKEISILNIARHRNILH 32236
Query: 204 IHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHSNG 263
+H+S V IF+ ISG D+F + ++E E + ++Q+ AL+FLHS+
Sbjct: 32237 LHESFESMEELVMIFE-FISGLDIFERI--NTSAFELNEREIVSYVHQVCEALQFLHSHN 32293
Query: 264 IVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKAD 323
I H D++ +NI+ T T + + +FG A++L R+ + PEY APEV
Sbjct: 32294 IGHFDIRPENIIYQTRRSST-IKIIEFGQARQLKPGDNFRL--LFTAPEYYAPEVH---- 32346
Query: 324 RNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVRTGK 383
TAT D+WSLG + +++L+GI+PF + ++ II+N+ +
Sbjct: 32347 ---QHDVVSTAT------------DMWSLGTLVYVLLSGINPFLAETNQ-QIIENIMNAE 32390
Query: 384 LNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKHTSQLERIYKKKVLQL 443
F + I+ A FV + L +R EAL W+++ ++ER+ K + L
Sbjct: 32391 YTFDEEAFKEISIEAMDFVDRLLVKERKSRMTASEALQHPWLKQ---KIERVSTKVIRTL 32447
>At4g23650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 529
Score = 109 bits (272), Expect = 1e-23
Identities = 87/288 (30%), Positives = 142/288 (49%), Gaps = 34/288 (11%)
Query: 143 RIVGSGTFGHVLVAEKVDHN-MKRQVAKKTVSYAVKVINTAKTRMVKEATILEKLN-HPN 200
R +G G FG V V H K+QVA K++ V + +E I+ L+ H N
Sbjct: 82 RELGRGQFG---VTYLVTHKETKQQVACKSIPTRRLVHKDDIEDVRREVQIMHHLSGHRN 138
Query: 201 IIRIHQSCVDALGNVYIFQDLISGGDLFS-YLAKGDCLVPISETESLIIIYQILLALKFL 259
I+ + + D +V + +L GG+LF ++KG SE + + Q+++ +
Sbjct: 139 IVDLKGAYEDR-HSVNLIMELCEGGELFDRIISKG----LYSERAAADLCRQMVMVVHSC 193
Query: 260 HSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVG 319
HS G++HRDLK +N L + + + + DFG++ K + +VG+ Y APEV
Sbjct: 194 HSMGVMHRDLKPENFLFLSKDENSPLKATDFGLSVFFKPGDKFK--DLVGSAYYVAPEV- 250
Query: 320 FKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNV 379
RN Y + DIWS GVI +I+L+G+ PF+G+ +E I +
Sbjct: 251 --LKRN-----------------YGPEADIWSAGVILYILLSGVPPFWGE-NETGIFDAI 290
Query: 380 RTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEK 427
G+L+F+A W A++D AK V+K L+ +R E L+ W+ +
Sbjct: 291 LQGQLDFSADPWPALSDGAKDLVRKMLKYDPKDRLTAAEVLNHPWIRE 338
>At4g18700 [T] KOG0583 Serine/threonine protein kinase
Length = 489
Score = 109 bits (272), Expect = 1e-23
Identities = 87/327 (26%), Positives = 152/327 (45%), Gaps = 57/327 (17%)
Query: 143 RIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKT-------RMVKEATILEK 195
+++G GTF V +A V K S A+KVI+ K + +E +IL +
Sbjct: 30 KLLGHGTFAKVYLARNV---------KTNESVAIKVIDKEKVLKGGLIAHIKREISILRR 80
Query: 196 LNHPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLA 255
+ HPNI+++ + + +Y + + GG+LF+ +AKG + E + Q++ A
Sbjct: 81 VRHPNIVQLFE-VMATKAKIYFVMEYVRGGELFNKVAKGR----LKEEVARKYFQQLISA 135
Query: 256 LKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERM-HTVVGTPEYC 314
+ F H+ G+ HRDLK +N+LL + + ++DFG++ Q ++ + HT GTP Y
Sbjct: 136 VTFCHARGVYHRDLKPENLLL---DENGNLKVSDFGLSAVSDQIRQDGLFHTFCGTPAYV 192
Query: 315 APEVGFKADRNIYRSFSRTATLDPDNNGYD-SKCDIWSLGVITHIMLTGISPFYGDGSEA 373
APEV + GYD +K DIWS GVI +++ G PF+ D +
Sbjct: 193 APEVLAR-------------------KGYDAAKVDIWSCGVILFVLMAGYLPFH-DRNVM 232
Query: 374 SIIKNVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKHTSQLE 433
++ K + G+ F +W + + K L+ + R E + W +K ++
Sbjct: 233 AMYKKIYRGE--FRCPRW--FSTELTRLLSKLLETNPEKRFTFPEIMENSWFKKGFKHIK 288
Query: 434 RIYKKKVL-------QLSSDCIKIDEN 453
+ L +L SD ++ D +
Sbjct: 289 FYVEDDKLCNVVDDDELESDSVESDRD 315
>7294770 [T] KOG0603 Ribosomal protein S6 kinase
Length = 1207
Score = 109 bits (272), Expect = 1e-23
Identities = 79/276 (28%), Positives = 143/276 (51%), Gaps = 35/276 (12%)
Query: 138 WKIVPRIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKT--RMVKEATILEK 195
+KI+ R++G+G +G V + K+ + ++ V + V+ KT E +LE
Sbjct: 261 FKII-RVLGTGAYGRVFLVRKLTRHDAGKLYAMKVLNKITVVQKRKTAEHTKTERVVLEA 319
Query: 196 LN-HPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILL 254
+ +P ++ +H + + +Y+ D +GG+LF++L + E+ + I +++L
Sbjct: 320 IQRNPFLVSLHYA-FQSSSKLYLVLDFANGGELFTHLYHSE---NFEESRVRVYIAEVVL 375
Query: 255 ALKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYC 314
AL+ LH GI++RD+KL+NILL + +VL+DFG++K L+ + R H+ GT EY
Sbjct: 376 ALEQLHQLGIIYRDIKLENILL---DGEGHIVLSDFGLSKILTAENEYRAHSFCGTLEYM 432
Query: 315 APEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFY---GDGS 371
APE+ + G+DS D WS+GV+T +LTG SPF G
Sbjct: 433 APEI-----------------IRTGPPGHDSAVDWWSVGVLTFELLTGASPFATSDGQVQ 475
Query: 372 EASIIKNVRTGKLNFTARQWIAITDSAKSFVKKCLQ 407
++ I + ++ + + + + +A+ FV K L+
Sbjct: 476 QSEISRRIQKEQPMIPS----SFSANARDFVLKMLE 507
Score = 65.5 bits (158), Expect = 2e-10
Identities = 61/246 (24%), Positives = 103/246 (41%), Gaps = 42/246 (17%)
Query: 193 LEKLNHPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQI 252
L+ NH NI+ H + + +I + +SG +L + + + E I Q+
Sbjct: 672 LDTTNHKNIVSYHGTFREKC-ETWIVMEYLSGPELTASIR-------MDEDSCREIFLQL 723
Query: 253 LLALKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIA----KELSQNTKERMHTVV 308
++A++ +HS +H DLK +NI+ E T V L DFG A + S K R
Sbjct: 724 VMAVRHIHSKHFIHGDLKPENIMFENREDRT-VKLIDFGSACYNNRFKSWKDKPRY---- 778
Query: 309 GTPEYCAPEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPF-- 366
T +Y PE+ AD N+ Y DI+ LG + ML G P+
Sbjct: 779 -TLDYAPPEM--LADANLVT--------------YSPAVDIYGLGATLYTMLVGHRPYRQ 821
Query: 367 ------YGDGSEASIIKNVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEAL 420
+ + + K +R G N + +W + + + + V CLQ +R + + L
Sbjct: 822 NEDDVDHSAAAHHELRKRMRRGTFNQRSMRWESASPAFRHLVSWCLQRDPADRPTLSDIL 881
Query: 421 HQVWVE 426
W++
Sbjct: 882 DSEWLQ 887
>Hs22057171 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 456
Score = 108 bits (271), Expect = 1e-23
Identities = 76/289 (26%), Positives = 142/289 (48%), Gaps = 39/289 (13%)
Query: 144 IVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTA----KTRMVKEATILEKLNHP 199
+ G G FG V E+ +K A K+I T K + E +++ +L+H
Sbjct: 179 LFGRGRFGQVHKCEETATGLK---------LAAKIIKTRGMKDKEEVKNEISVMNQLDHA 229
Query: 200 NIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFL 259
N+I+++ + ++ ++ + + + GG+LF + D ++E ++++ + QI ++ +
Sbjct: 230 NLIQLYDA-FESKNDIVLVMEYVDGGELFDRII--DESYNLTELDTILFMKQICEGIRHM 286
Query: 260 HSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVG 319
H I+H DLK +NIL + ++ + DFG+A+ +E++ GTPE+ APEV
Sbjct: 287 HQMYILHLDLKPENILCVNRD-AKQIKIIDFGLARRYKP--REKLKVNFGTPEFLAPEV- 342
Query: 320 FKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNV 379
+ F T D+WS+GVI +++L+G+SPF GD ++A + N+
Sbjct: 343 ------VNYDFVSFPT------------DMWSVGVIAYMLLSGLSPFLGD-NDAETLNNI 383
Query: 380 RTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKH 428
+ + ++ I++ AK F+ K L R EAL W+ H
Sbjct: 384 LACRWDLEDEEFQDISEEAKEFISKLLIKEKSWRISASEALKHPWLSDH 432
>At5g58380 [T] KOG0583 Serine/threonine protein kinase
Length = 464
Score = 108 bits (271), Expect = 1e-23
Identities = 82/314 (26%), Positives = 142/314 (45%), Gaps = 50/314 (15%)
Query: 141 VPRIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMV-------KEATIL 193
V R++G GTF V + N S A+K+I+ K V +E +++
Sbjct: 14 VGRLLGQGTFAKVYYGRSILTNQ---------SVAIKMIDKEKVMKVGLIEQIKREISVM 64
Query: 194 EKLNHPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQIL 253
HPN++ +++ +Y + GG+LF+ +AKG + + + YQ++
Sbjct: 65 RIARHPNVVELYEVMATKT-RIYFVMEYCKGGELFNKVAKGK----LRDDVAWKYFYQLI 119
Query: 254 LALKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKE-RMHTVVGTPE 312
A+ F HS + HRD+K +N+LL E + ++DFG++ ++ +HT GTP
Sbjct: 120 NAVDFCHSREVYHRDIKPENLLLDDNE---NLKVSDFGLSALADCKRQDGLLHTTCGTPA 176
Query: 313 YCAPEVGFKADRNIYRSFSRTATLDPDNNGYD-SKCDIWSLGVITHIMLTGISPFYGDGS 371
Y APEV + GYD +K DIWS GV+ ++L G PF+ D +
Sbjct: 177 YVAPEV-------------------INRKGYDGTKADIWSCGVVLFVLLAGYLPFH-DSN 216
Query: 372 EASIIKNVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKHTSQ 431
+ + + GK +F A W A + + K L + R + W K
Sbjct: 217 LMEMYRKI--GKADFKAPSWFA--PEVRRLLCKMLDPNPETRITIARIRESSWFRKGLHM 272
Query: 432 LERIYKKKVLQLSS 445
++ +K+V +++S
Sbjct: 273 KQKKMEKRVKEINS 286
>At5g45820 [T] KOG0583 Serine/threonine protein kinase
Length = 439
Score = 108 bits (271), Expect = 1e-23
Identities = 81/301 (26%), Positives = 139/301 (45%), Gaps = 52/301 (17%)
Query: 143 RIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMV-------KEATILEK 195
R++G GTF V A + K S A+KVI+ K V +E +++
Sbjct: 16 RLLGQGTFAKVYHARNI---------KTGESVAIKVIDKQKVAKVGLIDQIKREISVMRL 66
Query: 196 LNHPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLA 255
+ HP+++ +H+ +Y + + GG+LF ++KG + E + Q++ A
Sbjct: 67 VRHPHVVFLHEVMASKT-KIYFAMEYVKGGELFDKVSKGK----LKENIARKYFQQLIGA 121
Query: 256 LKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGI-AKELSQNTKERMHTVVGTPEYC 314
+ + HS G+ HRDLK +N+LL + + ++DFG+ A S+ +HT GTP Y
Sbjct: 122 IDYCHSRGVYHRDLKPENLLL---DENGDLKISDFGLSALRESKQQDGLLHTTCGTPAYV 178
Query: 315 APEVGFKADRNIYRSFSRTATLDPDNNGYD-SKCDIWSLGVITHIMLTGISPFYGDGSEA 373
APEV K GYD +K D+WS GV+ +++L G PF+ E
Sbjct: 179 APEVIGK-------------------KGYDGAKADVWSCGVVLYVLLAGFLPFH----EQ 215
Query: 374 SIIKNVR-TGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKHTSQL 432
++++ R K F W K + + L + +R +E+ + W +K ++
Sbjct: 216 NLVEMYRKITKGEFKCPNW--FPPEVKKLLSRILDPNPNSRIKIEKIMENSWFQKGFKKI 273
Query: 433 E 433
E
Sbjct: 274 E 274
>At5g01810 [T] KOG0583 Serine/threonine protein kinase
Length = 421
Score = 108 bits (271), Expect = 1e-23
Identities = 86/290 (29%), Positives = 134/290 (45%), Gaps = 38/290 (13%)
Query: 141 VPRIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVK-EATILEKLNHP 199
V + +G GTF V A + VA K + +++ T +K E + + L HP
Sbjct: 14 VGKFLGQGTFAKVYHARHLKTG--DSVAIKVIDKE-RILKVGMTEQIKREISAMRLLRHP 70
Query: 200 NIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFL 259
NI+ +H+ + +Y + + GG+LF+ ++ G + E + Q++ A+ F
Sbjct: 71 NIVELHE-VMATKSKIYFVMEHVKGGELFNKVSTGK----LREDVARKYFQQLVRAVDFC 125
Query: 260 HSNGIVHRDLKLDNILLHTPEPCTKVVLADFGI-AKELSQNTKERMHTVVGTPEYCAPEV 318
HS G+ HRDLK +N+LL + + ++DFG+ A S+ +HT GTP Y APEV
Sbjct: 126 HSRGVCHRDLKPENLLL---DEHGNLKISDFGLSALSDSRRQDGLLHTTCGTPAYVAPEV 182
Query: 319 GFKADRNIYRSFSRTATLDPDNNGYDS-KCDIWSLGVITHIMLTGISPFYGDGSEASIIK 377
SR NGYD K D+WS GVI ++L G PF D + + K
Sbjct: 183 -----------ISR--------NGYDGFKADVWSCGVILFVLLAGYLPF-RDSNLMELYK 222
Query: 378 NVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEK 427
+ GK W+A AK +K+ L + R E+ + W K
Sbjct: 223 KI--GKAEVKFPNWLA--PGAKRLLKRILDPNPNTRVSTEKIMKSSWFRK 268
>7299507 [T] KOG0607 MAP kinase-interacting kinase and related
serine/threonine protein kinases
Length = 1142
Score = 108 bits (271), Expect = 1e-23
Identities = 87/334 (26%), Positives = 143/334 (42%), Gaps = 53/334 (15%)
Query: 118 KSETMSQFMTGLRIKSEWDRWKIVPRIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVK 177
K + + L + + +K+ I+G G + V + +++ YAVK
Sbjct: 97 KKRRKKRISSSLHSSTFQELYKLTGEILGEGAYASVQTCVNIYTDLE---------YAVK 147
Query: 178 VINT----AKTRMVKEA-TILEKLNHPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLA 232
VI+ A+ R+ +E T H I+++ + D Y+ + I+GG L S +
Sbjct: 148 VIDKIPGHARARVFREVETFHHCQGHLGILQLIEFFEDD-EKFYLVFEKINGGPLLSRIQ 206
Query: 233 KGDCLVPISETESLIIIYQILLALKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGI 292
+ C SE E+ II +I L FLH GI HRDLK +NIL + + + DF +
Sbjct: 207 EHICF---SEHEASQIIKEIASGLDFLHKKGIAHRDLKPENILCVKTDSLCPIKICDFDL 263
Query: 293 AKELSQNTK-------ERMHTVVGTPEYCAPEVGFKADRNIYRSFSRTATLDPDNNGYDS 345
+ T ++ T VG+ E+ APEV + + YD
Sbjct: 264 GSGIKFTTDISSPAATPQLLTPVGSAEFMAPEV--------------VDLFVGEAHYYDK 309
Query: 346 KCDIWSLGVITHIMLTGISPFYGDGSE--------------ASIIKNVRTGKLNFTARQW 391
+CD+WSLGVI +I+L G PF G+ E + ++++ G +F +W
Sbjct: 310 RCDLWSLGVIAYILLCGYPPFSGNCGEDCGWNRGENCRTCQELLFESIQEGHFSFPEAEW 369
Query: 392 IAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWV 425
++D AK + L NR E L+ W+
Sbjct: 370 HDVSDEAKDLISNLLVKKASNRLSAEAVLNHPWI 403
>7299438 [R] KOG0586 Serine/threonine protein kinase
Length = 705
Score = 108 bits (271), Expect = 1e-23
Identities = 83/316 (26%), Positives = 155/316 (48%), Gaps = 39/316 (12%)
Query: 138 WKIVPRIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKLN 197
+KI+ + +G G F V +A V R+VA K + ++ +A+ ++ +E I++ LN
Sbjct: 98 YKII-KTLGKGNFAKVKLAIHVPTG--REVAIKVID-KTQLNTSARQKLYREVKIMKLLN 153
Query: 198 HPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALK 257
HPNI+R+ Q +++ +Y+ + S G+LF +L K + E ++ +I Q++ A++
Sbjct: 154 HPNIVRLFQ-VIESERTLYLVMEYASRGELFDHLVKNGRM---RERDARVIFRQLVSAIQ 209
Query: 258 FLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPE 317
+ HS +VHRDLK +N+LL + + +ADFG N ++ T G+P Y APE
Sbjct: 210 YCHSKFVVHRDLKAENLLL---DQHMNIKIADFGFGNTFDPNA--QLETFCGSPPYAAPE 264
Query: 318 VGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIK 377
+ F P+ D WSLGV+ + +++G PF G +K
Sbjct: 265 L-----------FMGRKYAGPE-------VDAWSLGVVLYTLVSGSLPFDG-----GTLK 301
Query: 378 NVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKHTSQLERI-- 435
+R L R I+ ++ ++K L ++ R + + W+ + +R+
Sbjct: 302 ELRERVLRGKYRVPYYISMDCENLMRKFLVLNPAKRTSLSAVMSDKWINLGHDESDRLRP 361
Query: 436 YKKKVLQLSSDCIKID 451
+++K ++L D + D
Sbjct: 362 FREKPMEL-QDAARFD 376
>SPBC32C12.03c [T] KOG0583 Serine/threonine protein kinase
Length = 423
Score = 108 bits (270), Expect = 2e-23
Identities = 87/292 (29%), Positives = 147/292 (49%), Gaps = 38/292 (13%)
Query: 140 IVPRIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKT-RMVKEATILEKLNH 198
I+ + +G+G+ G V + + K A K + + NT++T R+ +EA + L H
Sbjct: 54 IIKKTIGAGSMGKVKLVVNILTGEK--AALKMIPFTPN--NTSQTVRVQREALLGRLLRH 109
Query: 199 PNIIRIHQSCVDALGNVYIFQDLISGGDLFSY-LAKGDCLVPISETESLIIIYQILLALK 257
PNI R+ C+ YI + + GG L Y LA+G + E + Q++ AL
Sbjct: 110 PNICRVID-CIRTPACTYILFEYVPGGQLLEYILARGK----LDEDLARSFAMQLINALV 164
Query: 258 FLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPE 317
+LH N IVHRDLK++N+LL + +V L DFG++ S++ + + T G+ + APE
Sbjct: 165 YLHKNFIVHRDLKIENVLL--TQDSRQVKLIDFGLSNFYSKD--DLLRTYCGSLYFAAPE 220
Query: 318 VGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIK 377
+ D Y + P+ D+WSLGV+ ++M+ G PF D S +
Sbjct: 221 L---LDAKPY--------IGPE-------VDVWSLGVVIYVMVCGRVPF-DDVSVPMLHS 261
Query: 378 NVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKHT 429
+++GKL F + I++ S + L V+ RC +E+A W++K++
Sbjct: 262 KIKSGKLEFPS----YISEDCCSLIAAMLNVNPRKRCSLEQAAKFPWLKKNS 309
>At2g41860 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 530
Score = 108 bits (270), Expect = 2e-23
Identities = 79/305 (25%), Positives = 145/305 (46%), Gaps = 42/305 (13%)
Query: 127 TGLRIKSEWDRWKIVPRIVGSGTFGHVLVAEKVDHN---MKRQVAKKTVSYAVKVINTAK 183
TG IK ++ + R +G G FG + +++ + + KK + ++ + + +
Sbjct: 46 TGHEIKQKYK----LGRELGRGEFGVTYLCTEIETGEIFACKSILKKKLKTSIDIEDVKR 101
Query: 184 TRMVKEATILEKL-NHPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYL-AKGDCLVPIS 241
E I+ ++ HPNI+ + ++ D V++ +L GG+LF + A+G +
Sbjct: 102 -----EVEIMRQMPEHPNIVTLKETYEDDKA-VHLVMELCEGGELFDRIVARGH----YT 151
Query: 242 ETESLIIIYQILLALKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTK 301
E + +I I+ ++ H +G++HRDLK +N L + + DFG++
Sbjct: 152 ERAAASVIKTIIEVVQMCHKHGVMHRDLKPENFLFANKKETASLKAIDFGLSVFFKPG-- 209
Query: 302 ERMHTVVGTPEYCAPEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLT 361
ER + +VG+P Y APEV + RS Y + DIWS GVI +I+L
Sbjct: 210 ERFNEIVGSPYYMAPEV-------LRRS-------------YGQEIDIWSAGVILYILLC 249
Query: 362 GISPFYGDGSEASIIKNVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALH 421
G+ PF+ + +E + K + ++F W ++D+AK +KK L R ++ L
Sbjct: 250 GVPPFWAE-TEHGVAKAILKSVIDFKRDPWPKVSDNAKDLIKKMLHPDPRRRLTAQQVLD 308
Query: 422 QVWVE 426
W++
Sbjct: 309 HPWIQ 313
>At1g74740 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 567
Score = 108 bits (269), Expect = 2e-23
Identities = 81/283 (28%), Positives = 135/283 (47%), Gaps = 32/283 (11%)
Query: 140 IVPRIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKL-NH 198
I+ R +G G FG + D + +A K++S + +E TI+ L H
Sbjct: 60 ILGRELGRGEFGITYLC--TDRETREALACKSISKRKLRTAVDVEDVRREVTIMSTLPEH 117
Query: 199 PNIIRIHQSCVDALGNVYIFQDLISGGDLFSYL-AKGDCLVPISETESLIIIYQILLALK 257
PN++++ + D NV++ +L GG+LF + A+G +E + + I ++
Sbjct: 118 PNVVKLKATYEDN-ENVHLVMELCEGGELFDRIVARGH----YTERAAATVARTIAEVVR 172
Query: 258 FLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPE 317
H NG++HRDLK +N L + + + DFG++ ER +VG+P Y APE
Sbjct: 173 MCHVNGVMHRDLKPENFLFANKKENSALKAIDFGLSVLFKPG--ERFTEIVGSPYYMAPE 230
Query: 318 VGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIK 377
V RN Y + D+WS GVI +I+L G+ PF+ + +E +
Sbjct: 231 V---LKRN-----------------YGPEVDVWSAGVILYILLCGVPPFWAE-TEQGVAL 269
Query: 378 NVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEAL 420
+ G L+F W I++SAKS VK+ L+ + R ++ L
Sbjct: 270 AILRGVLDFKRDPWSQISESAKSLVKQMLEPDSTKRLTAQQVL 312
>At1g48260 [T] KOG0583 Serine/threonine protein kinase
Length = 432
Score = 108 bits (269), Expect = 2e-23
Identities = 79/255 (30%), Positives = 133/255 (51%), Gaps = 44/255 (17%)
Query: 173 SYAVKVINTA-------KTRMVKEATILEKLNHPNIIRIHQSCVDALGNVYIFQDLISGG 225
S+A+K+I + ++ +E L+ L HPNI+R+H+ +Y+ + ++GG
Sbjct: 36 SFAIKIIEKSCITRLNVSFQIKREIRTLKVLKHPNIVRLHEVLASKT-KIYMVLECVTGG 94
Query: 226 DLFSYL-AKGDCLVPISETESLIIIYQILLALKFLHSNGIVHRDLKLDNILLHTPEPCTK 284
DLF + +KG +SET+ + Q++ + + H+ G+ HRDLKL+N+LL +
Sbjct: 95 DLFDRIVSKGK----LSETQGRKMFQQLIDGVSYCHNKGVFHRDLKLENVLL---DAKGH 147
Query: 285 VVLADFGIAKELSQNTKE--RMHTVVGTPEYCAPEVGFKADRNIYRSFSRTATLDPDNNG 342
+ + DFG++ LSQ+ +E +HT G+P Y APEV N G
Sbjct: 148 IKITDFGLS-ALSQHYREDGLLHTTCGSPNYVAPEV-------------------LANEG 187
Query: 343 YD-SKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVRTGKLNFTARQWIAITDSAKSF 401
YD + DIWS GVI +++LTG PF D + A I + + G + +WI++ AK+
Sbjct: 188 YDGAASDIWSCGVILYVILTGCLPF-DDANLAVICRKIFKG--DPPIPRWISL--GAKTM 242
Query: 402 VKKCLQVSTFNRCDV 416
+K+ L + R +
Sbjct: 243 IKRMLDPNPVTRVTI 257
>Hs5902140_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 304
Score = 108 bits (269), Expect = 2e-23
Identities = 82/291 (28%), Positives = 136/291 (46%), Gaps = 32/291 (10%)
Query: 145 VGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKLNHPNIIRI 204
+G G F +V + + ++ VA K VS +K K + EA +L+ L HP I +
Sbjct: 8 IGRGRFS--IVKKCIHKATRKDVAVKFVSKKMK----KKEQAAHEAALLQHLQHPQYITL 61
Query: 205 HQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHSNGI 264
H + + I + L+ G L YL D L+ E + I I+ AL++LH+ +
Sbjct: 62 HDTYESPTSYILILE-LMDDGRLLDYLMNHDELM---EEKVAFYIRDIMEALQYLHNCRV 117
Query: 265 VHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKADR 324
H D+K +N+L+ P +V L D A ++S + +H ++G PE+ APEV +
Sbjct: 118 AHLDIKPENLLIDLRIPVPRVKLIDLEDAVQISGHF--HIHHLLGNPEFAAPEV----IQ 171
Query: 325 NIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVRTGKL 384
I S DIWS+GV+T++ML+G+SPF + E + I NV
Sbjct: 172 GIPVSLG---------------TDIWSIGVLTYVMLSGVSPFLDESKEETCI-NVCRVDF 215
Query: 385 NFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKHTSQLERI 435
+F + ++++A+ F+ LQ R L W++ H +I
Sbjct: 216 SFPHEYFCGVSNAARDFINVILQEDFRRRPTAATCLQHPWLQPHNGSYSKI 266
>YMR001c [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 705
Score = 107 bits (268), Expect = 3e-23
Identities = 88/331 (26%), Positives = 149/331 (44%), Gaps = 40/331 (12%)
Query: 168 AKKTVSYAVKVINTAKTRMVKEATILEKLNHPNIIRIHQSCVDALGNVYIFQDLISGGDL 227
A KTV+ A + +++ E I + ++HPNI++ C + NVYI ++ G L
Sbjct: 108 AAKTVAKASIKSEKTRKKLLSEIQIHKSMSHPNIVQFID-CFEDDSNVYILLEICPNGSL 166
Query: 228 FSYLAKGDCLVPISETESLIIIYQILLALKFLHSNGIVHRDLKLDNILLHTPEPCTKVVL 287
L + L +E E QI A+K++HS ++HRDLKL NI + + +
Sbjct: 167 MELLKRRKVL---TEPEVRFFTTQICGAIKYMHSRRVIHRDLKLGNIFF---DSNYNLKI 220
Query: 288 ADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKADRNIYRSFSRTATLDPDNNGYDSKC 347
DFG+A L+ N ER +T+ GTP Y APEV L ++G+ +
Sbjct: 221 GDFGLAAVLA-NESERKYTICGTPNYIAPEV-----------------LMGKHSGHSFEV 262
Query: 348 DIWSLGVITHIMLTGISPFYGDGSEASIIKNVRTGKLNFTARQWIAITDSAKSFVKKCLQ 407
DIWSLGV+ + +L G PF +I + ++ +F + I+D K ++ L
Sbjct: 263 DIWSLGVMLYALLIGKPPFQARDVN-TIYERIKCRDFSFPRDK--PISDEGKILIRDILS 319
Query: 408 VSTFNRCDVEEALHQVW------------VEKHTSQLERIYKKKVLQLSSDCIKIDENID 455
+ R + E + VW V E I +++ L DC++ ++
Sbjct: 320 LDPIERPSLTEIMDYVWFRGTFPPSIPSTVMSEAPNFEDIPEEQSLVNFKDCMEKSLLLE 379
Query: 456 TFAVVKHKLPKSVKLSPEKNPNKRLKLFSNN 486
+ + K + K +S K+ +L+ + N
Sbjct: 380 SMSSDKIQRQKRDYISSIKSSIDKLEEYHQN 410
>Hs4506739 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 495
Score = 107 bits (268), Expect = 3e-23
Identities = 84/267 (31%), Positives = 129/267 (47%), Gaps = 34/267 (12%)
Query: 143 RIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAK--TRMVKEATILEKLNHPN 200
R++G G +G V KV ++ V K++ AK E ILE + HP
Sbjct: 84 RVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNILESVKHPF 143
Query: 201 IIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLH 260
I+ + + G +Y+ + +SGG+LF++L + + E + + +I LAL LH
Sbjct: 144 IVELAYAFQTG-GKLYLILECLSGGELFTHLEREGIFL---EDTACFYLAEITLALGHLH 199
Query: 261 SNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGF 320
S GI++RDLK +NI+L + + L DFG+ KE S + HT GT EY APE+
Sbjct: 200 SQGIIYRDLKPENIMLSSQ---GHIKLTDFGLCKE-SIHEGAVTHTFCGTIEYMAPEI-- 253
Query: 321 KADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVR 380
+ RS G++ D WSLG + + MLTG PF + + ++ K +R
Sbjct: 254 -----LVRS------------GHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIR 296
Query: 381 TGKLNFTARQWIAITDSAKSFVKKCLQ 407
GKL +T A+ VKK L+
Sbjct: 297 -GKLALPP----YLTPDARDLVKKFLK 318
>Hs20545357 [T] KOG0583 Serine/threonine protein kinase
Length = 436
Score = 107 bits (268), Expect = 3e-23
Identities = 77/282 (27%), Positives = 137/282 (48%), Gaps = 35/282 (12%)
Query: 145 VGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKLNHPNIIRI 204
+GSG F V + H++ ++ + K+ + + +E + +EKL+HPNIIR+
Sbjct: 80 IGSGNFSQVKLGI---HSLTKEKVAIKILDKTKLDQKTQRLLSREISSMEKLHHPNIIRL 136
Query: 205 HQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHSNGI 264
++ V+ L +++ + GG+LF ++ L SE ES +I QI+ A+K +H N I
Sbjct: 137 YE-VVETLSKLHLVMEYAGGGELFGKISTEGKL---SEPESKLIFSQIVSAVKHMHENQI 192
Query: 265 VHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKADR 324
+HRDLK +N+ +T C KV DFG + + E ++T G+P Y APE
Sbjct: 193 IHRDLKAENV-FYTSNTCVKV--GDFGFSTVSKKG--EMLNTFCGSPPYAAPE------- 240
Query: 325 NIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVRTGKL 384
L D + DIW+LGV+ + M+TG PF + + A + K++ G
Sbjct: 241 -----------LFRDEHYIGIYVDIWALGVLLYFMVTGTMPFRAE-TVAKLKKSILEGTY 288
Query: 385 NFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVE 426
+ +++ ++ LQ R ++ ++ W++
Sbjct: 289 SVPPH----VSEPCHRLIRGVLQQIPTERYGIDCIMNDEWMQ 326
>CE06635 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 7160
Score = 107 bits (268), Expect = 3e-23
Identities = 81/286 (28%), Positives = 137/286 (47%), Gaps = 41/286 (14%)
Query: 145 VGSGTFGHV-LVAEKVDHNMKRQVAKKTVSYAVKVINTA----KTRMVKEATILEKLNHP 199
+G+G FG V V E+ N ++A K + T K + KE + L HP
Sbjct: 6269 LGTGAFGVVHRVTERATGN----------NFAAKFVMTPHESDKETVRKEIQTMSVLRHP 6318
Query: 200 NIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFL 259
++ +H + D V I++ +SGG+LF +A D +SE E++ + Q+ L +
Sbjct: 6319 TLVNLHDAFEDDNEMVMIYE-FMSGGELFEKVA--DEHNKMSEDEAVEYMRQVCKGLCHM 6375
Query: 260 HSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVG 319
H N VH DLK +NI+ T + ++ L DFG+ L + K+ + GT E+ APEV
Sbjct: 6376 HENNYVHLDLKPENIMF-TTKRSNELKLIDFGLTAHL--DPKQSVKVTTGTAEFAAPEVA 6432
Query: 320 FKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNV 379
Y D+WS+GV+++I+L+G+SPF G+ + + ++NV
Sbjct: 6433 EGKPVGYYT-------------------DMWSVGVLSYILLSGLSPFGGENDDET-LRNV 6472
Query: 380 RTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWV 425
++ N + I++ K F++K L R + +AL W+
Sbjct: 6473 KSCDWNMDDSAFSGISEDGKDFIRKLLLADPNTRMTIHQALEHPWL 6518
>CE06634 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 6831
Score = 107 bits (268), Expect = 3e-23
Identities = 81/286 (28%), Positives = 137/286 (47%), Gaps = 41/286 (14%)
Query: 145 VGSGTFGHV-LVAEKVDHNMKRQVAKKTVSYAVKVINTA----KTRMVKEATILEKLNHP 199
+G+G FG V V E+ N ++A K + T K + KE + L HP
Sbjct: 5940 LGTGAFGVVHRVTERATGN----------NFAAKFVMTPHESDKETVRKEIQTMSVLRHP 5989
Query: 200 NIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFL 259
++ +H + D V I++ +SGG+LF +A D +SE E++ + Q+ L +
Sbjct: 5990 TLVNLHDAFEDDNEMVMIYE-FMSGGELFEKVA--DEHNKMSEDEAVEYMRQVCKGLCHM 6046
Query: 260 HSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVG 319
H N VH DLK +NI+ T + ++ L DFG+ L + K+ + GT E+ APEV
Sbjct: 6047 HENNYVHLDLKPENIMF-TTKRSNELKLIDFGLTAHL--DPKQSVKVTTGTAEFAAPEVA 6103
Query: 320 FKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNV 379
Y D+WS+GV+++I+L+G+SPF G+ + + ++NV
Sbjct: 6104 EGKPVGYYT-------------------DMWSVGVLSYILLSGLSPFGGENDDET-LRNV 6143
Query: 380 RTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWV 425
++ N + I++ K F++K L R + +AL W+
Sbjct: 6144 KSCDWNMDDSAFSGISEDGKDFIRKLLLADPNTRMTIHQALEHPWL 6189
>At3g10660 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 646
Score = 107 bits (268), Expect = 3e-23
Identities = 82/285 (28%), Positives = 138/285 (47%), Gaps = 30/285 (10%)
Query: 143 RIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKL-NHPNI 201
R +G G FG + ++ + A K++S + + + +E I+ L HPN+
Sbjct: 190 RKLGQGQFGTTFLC--LEKGTGNEYACKSISKRKLLTDEDVEDVRREIQIMHHLAGHPNV 247
Query: 202 IRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHS 261
I I + D + V++ +L SGG+LF + + +E ++ + I+ L+ HS
Sbjct: 248 ISIKGAYEDVVA-VHLVMELCSGGELFDRIIQRG---HYTERKAAELARTIVGVLEACHS 303
Query: 262 NGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFK 321
G++HRDLK +N L + E + + DFG++ + E VVG+P Y APEV K
Sbjct: 304 LGVMHRDLKPENFLFVSREEDSLLKTIDFGLSMFFKPD--EVFTDVVGSPYYVAPEVLRK 361
Query: 322 ADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVRT 381
Y + D+WS GVI +I+L+G+ PF+ + +E I + V
Sbjct: 362 R--------------------YGPESDVWSAGVIVYILLSGVPPFWAE-TEQGIFEQVLH 400
Query: 382 GKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVE 426
G L+F++ W +I++SAK V+K L R + L WV+
Sbjct: 401 GDLDFSSDPWPSISESAKDLVRKMLVRDPKRRLTAHQVLCHPWVQ 445
>At2g31500 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 582
Score = 107 bits (268), Expect = 3e-23
Identities = 84/326 (25%), Positives = 144/326 (43%), Gaps = 47/326 (14%)
Query: 145 VGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKL-NHPNIIR 203
+G G FG + E ++ + + + A K +S + +E I+ L HPNI+
Sbjct: 72 LGRGEFG--VTHECIEISTRERFACKRISKEKLRTEIDVEDVRREVEIMRCLPKHPNIVS 129
Query: 204 IHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHSNG 263
++ D VY+ ++ GG+LF + +E + + IL +K H +G
Sbjct: 130 FKEAFEDK-DAVYLVMEICEGGELFDRIVSRG---HYTERAAASVAKTILEVVKVCHEHG 185
Query: 264 IVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKAD 323
++HRDLK +N L ++ DFG++ + +R + +VG+P Y APEV
Sbjct: 186 VIHRDLKPENFLFSNGTETAQLKAIDFGLS--IFFKPAQRFNEIVGSPYYMAPEV---LR 240
Query: 324 RNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVRTGK 383
RN Y + D+WS GVI +I+L G+ PF+ + +E I + G
Sbjct: 241 RN-----------------YGPEIDVWSAGVILYILLCGVPPFWAE-TEEGIAHAIVRGN 282
Query: 384 LNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEK---------------- 427
++F W ++ AK VK L + ++R V+E L W+
Sbjct: 283 IDFERDPWPKVSHEAKELVKNMLDANPYSRLTVQEVLEHPWIRNAERAPNVNLGDNVRTK 342
Query: 428 -HTSQLERIYKKKVLQLSSDCIKIDE 452
L +KKKVL++ +D + +E
Sbjct: 343 IQQFLLMNRFKKKVLRIVADNLPNEE 368
>Hs13129008 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 501
Score = 107 bits (267), Expect = 4e-23
Identities = 82/290 (28%), Positives = 140/290 (48%), Gaps = 46/290 (15%)
Query: 189 EATILEKLNHPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLII 248
E IL+ + HPNI+++ V +IF +L +G ++F ++ SE ++ +
Sbjct: 70 EIGILKMVKHPNILQLVDVFVTRK-EYFIFLELATGREVFDWILDQGYY---SERDTSNV 125
Query: 249 IYQILLALKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVV 308
+ Q+L A+ +LHS IVHR+LKL+N++ + +K+V++DF +AK + KE
Sbjct: 126 VRQVLEAVAYLHSLKIVHRNLKLENLVYYNRLKNSKIVISDFHLAKLENGLIKE----PC 181
Query: 309 GTPEYCAPEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYG 368
GTPEY APEV Y D W++GVI +I+L+G PFY
Sbjct: 182 GTPEYLAPEV-------------------VGRQRYGRPVDCWAIGVIMYILLSGNPPFYE 222
Query: 369 DGSE-------ASIIKNVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALH 421
+ E ++ + + G F + W I+ +AK V + ++V R EEA+
Sbjct: 223 EVEEDDYENHDKNLFRKILAGDYEFDSPYWDDISQAAKDLVTRLMEVEQDQRITAEEAIS 282
Query: 422 QVWVEKHTSQLERIYKKKVLQLSSDCIKIDENIDTFAVVKHKLPKSVKLS 471
W+ + + + I C +I++N FA K K K+V+++
Sbjct: 283 HEWISGNAASDKNI-------KDGVCAQIEKN---FARAKWK--KAVRVT 320
>ECU07g0360 [D] KOG0580 Serine/threonine protein kinase
Length = 272
Score = 107 bits (267), Expect = 4e-23
Identities = 87/298 (29%), Positives = 150/298 (50%), Gaps = 44/298 (14%)
Query: 136 DRWKIVPRIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKT--RMVKEATIL 193
DR++I R++G G FG V +A + + VA K + +K I T +T ++ +E I
Sbjct: 8 DRFEI-GRLLGRGKFGQVWLAREREKGFI--VALKIIP--IKEIQTVETARQIRREIEIH 62
Query: 194 EKLNHPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQIL 253
L HPNI+R++ D N+Y+ + G+ F +L+ D E E+ + I Q++
Sbjct: 63 SNLKHPNILRMYGHFHDK-DNIYLILEYAGKGEFFKFLS--DRGGKFGEKETSLYIRQVM 119
Query: 254 LALKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEY 313
LAL ++ ++HRD+K +N+LL + ++ +ADFG A N +R T GT EY
Sbjct: 120 LALTYMKECNVIHRDIKPENLLLGSD---NQLKIADFGWA---VYNADKRRMTFCGTMEY 173
Query: 314 CAPEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEA 373
APE+ +N+ +DS D+W LG++T+ L G +PF
Sbjct: 174 LAPEM-------------------VNNDIHDSGIDLWCLGILTYEFLMGKTPF------E 208
Query: 374 SIIKNVRTGKLNFTARQWI---AITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKH 428
S +N+R + ++ I+ +A F+ + L +S +R ++ EAL+ ++ KH
Sbjct: 209 SKNRNMREAYKKINSLKYTIPETISSNASDFISRLLVLSPGDRMELTEALNHPFIVKH 266
>CE20167 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD and related
proteins
Length = 722
Score = 107 bits (267), Expect = 4e-23
Identities = 83/290 (28%), Positives = 139/290 (47%), Gaps = 39/290 (13%)
Query: 143 RIVGSGTFGHVLVAEKVDHNMKRQVAKKTVS---YAVKVINTAKTRMVKEATILEKLNHP 199
+ +GSG FG V A + + ++VA K +S ++ K + M E IL++ HP
Sbjct: 430 KTLGSGQFGTVYSA--IQRHSGKEVAVKVISKERFSKK--GSGAESMRAEVAILQQTCHP 485
Query: 200 NIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFL 259
I+ + C + +++ + ++G L L++ L ++ + ++ QIL ALK+L
Sbjct: 486 GIVCLEFMC-ETKDKIFVVMEKMNGDMLEMILSQE--LGRLNSRATKFLLVQILCALKYL 542
Query: 260 HSNGIVHRDLKLDNILLH---TPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAP 316
H GI H DLK +N+LL + P TK+ DFG A+ + ++ + TVVGTP Y P
Sbjct: 543 HDQGIAHCDLKPENVLLSDMGSNFPQTKI--CDFGYARFIPESQFRK--TVVGTPAYLPP 598
Query: 317 EVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASII 376
EV GY+ D+WS+GVI ++ L+G PF +G E S
Sbjct: 599 EV-------------------LQRKGYNKSLDMWSVGVIIYVTLSGTFPF-NEGEEIS-- 636
Query: 377 KNVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVE 426
+ ++ F W + A ++K L+V R +E+ L W++
Sbjct: 637 EQIQNASFMFPTEPWSEVEPLAVDLIQKLLKVEIEARMSIEQCLDHGWLK 686
>At4g04720 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 531
Score = 107 bits (267), Expect = 4e-23
Identities = 81/284 (28%), Positives = 139/284 (48%), Gaps = 32/284 (11%)
Query: 145 VGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKLN-HPNIIR 203
+G G FG + +++ A K++ + K + +E I++ L+ PNI+
Sbjct: 86 LGRGQFGITYMCKEIGTG--NTYACKSILKRKLISKQDKEDVKREIQIMQYLSGQPNIVE 143
Query: 204 IHQSCVDALGNVYIFQDLISGGDLFS-YLAKGDCLVPISETESLIIIYQILLALKFLHSN 262
I + D ++++ +L +GG+LF +A+G SE + II I+ ++ H
Sbjct: 144 IKGAYEDRQ-SIHLVMELCAGGELFDRIIAQGH----YSERAAAGIIRSIVNVVQICHFM 198
Query: 263 GIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKA 322
G+VHRDLK +N LL + E + DFG++ + + R +VG+ Y APEV
Sbjct: 199 GVVHRDLKPENFLLSSKEENAMLKATDFGLSVFIEEGKVYR--DIVGSAYYVAPEV---- 252
Query: 323 DRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVRTG 382
+ RS Y + DIWS GVI +I+L+G+ PF+ + +E I V G
Sbjct: 253 ---LRRS-------------YGKEIDIWSAGVILYILLSGVPPFWAE-NEKGIFDEVIKG 295
Query: 383 KLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVE 426
+++F + W +I++SAK V+K L R + L W++
Sbjct: 296 EIDFVSEPWPSISESAKDLVRKMLTKDPKRRITAAQVLEHPWIK 339
>At2g35890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 520
Score = 107 bits (267), Expect = 4e-23
Identities = 80/283 (28%), Positives = 135/283 (47%), Gaps = 32/283 (11%)
Query: 145 VGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEK--LNHPNII 202
+G G FG V V+ + A K++ K+ N V+ + K L PN+I
Sbjct: 138 LGHGQFGTTFVC--VEKGTGEEYACKSIPKR-KLENEEDVEDVRREIEIMKHLLGQPNVI 194
Query: 203 RIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHSN 262
I + D++ V++ +L GG+LF + + SE ++ + IL ++ HS
Sbjct: 195 SIKGAYEDSVA-VHMVMELCRGGELFDRIVERG---HYSERKAAHLAKVILGVVQTCHSL 250
Query: 263 GIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKA 322
G++HRDLK +N L + + + DFG++ L E VVG+P Y APEV
Sbjct: 251 GVMHRDLKPENFLFVNDDEDSPLKAIDFGLSMFLKPG--ENFTDVVGSPYYIAPEVL--- 305
Query: 323 DRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVRTG 382
N Y + DIWS GV+ +++L+G +PF+G+ +E I V G
Sbjct: 306 -----------------NKNYGPEADIWSAGVMIYVLLSGSAPFWGE-TEEEIFNEVLEG 347
Query: 383 KLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWV 425
+L+ T+ W +++SAK ++K L+ + R ++ L W+
Sbjct: 348 ELDLTSDPWPQVSESAKDLIRKMLERNPIQRLTAQQVLCHPWI 390
>YHR205w [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 824
Score = 107 bits (266), Expect = 5e-23
Identities = 88/269 (32%), Positives = 129/269 (47%), Gaps = 37/269 (13%)
Query: 141 VPRIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATIL---EKLN 197
V R++G GTFG V +K D +R A K +S V V + E IL +
Sbjct: 414 VLRLLGKGTFGQVYQVKKKD--TQRIYAMKVLSKKVIVKKNEIAHTIGERNILVTTASKS 471
Query: 198 HPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALK 257
P I+ + S ++Y+ D +SGG+LF +L K SE + I +++LAL+
Sbjct: 472 SPFIVGLKFS-FQTPTDLYLVTDYMSGGELFWHLQKEG---RFSEDRAKFYIAELVLALE 527
Query: 258 FLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPE 317
LH N IV+RDLK +NILL + + L DFG++K + K+R +T GT EY APE
Sbjct: 528 HLHDNDIVYRDLKPENILL---DANGNIALCDFGLSK---ADLKDRTNTFCGTTEYLAPE 581
Query: 318 VGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIK 377
L D GY D WSLGV+ M G SPF+ + ++ + +
Sbjct: 582 ------------------LLLDETGYTKMVDFWSLGVLIFEMCCGWSPFFAENNQ-KMYQ 622
Query: 378 NVRTGKLNFTARQWIAITDSAKSFVKKCL 406
+ GK+ F ++ +SFVK L
Sbjct: 623 KIAFGKVKFPRD---VLSQEGRSFVKGLL 648
>SPCC24B10.07 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 569
Score = 107 bits (266), Expect = 5e-23
Identities = 72/227 (31%), Positives = 117/227 (50%), Gaps = 29/227 (12%)
Query: 143 RIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKLNHPNII 202
++VG G+FG V+ K D + R A KT+ A V + + E T+L ++N+P I+
Sbjct: 234 KVVGKGSFGKVMQVRKRDTS--RIYALKTMKKAHIVSRSEVDHTLAERTVLAQVNNPFIV 291
Query: 203 RIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHSN 262
+ S + G +Y+ ++GG+LF +L + C + I ++L+AL+ LH
Sbjct: 292 PLKFS-FQSPGKLYLVLAFVNGGELFHHLQREGCF---DTYRAKFYIAELLVALECLHEF 347
Query: 263 GIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKA 322
+++RDLK +NILL + + L DFG+ K L+ +R +T GTPEY APE+
Sbjct: 348 NVIYRDLKPENILL---DYTGHIALCDFGLCK-LNMAKTDRTNTFCGTPEYLAPELLL-- 401
Query: 323 DRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGD 369
+GY D W+LGV+ + M+TG+ PFY +
Sbjct: 402 -----------------GHGYTKVVDWWTLGVLLYEMITGLPPFYDE 431
>At4g14580 [T] KOG0583 Serine/threonine protein kinase
Length = 426
Score = 107 bits (266), Expect = 5e-23
Identities = 91/346 (26%), Positives = 158/346 (45%), Gaps = 51/346 (14%)
Query: 143 RIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKL-NHPNI 201
R +GSG+F V VA + VA K + + + + R+++E + +L NHPN+
Sbjct: 25 RRLGSGSFAKVHVARSISTG--ELVAIKIIDKQKTIDSGMEPRIIREIEAMRRLHNHPNV 82
Query: 202 IRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHS 261
++IH+ + +Y+ + +GG+LF+ L + L +E+ + Q+ AL F H
Sbjct: 83 LKIHE-VMATKSKIYLVVEYAAGGELFTKLIRFGRL---NESAARRYFQQLASALSFCHR 138
Query: 262 NGIVHRDLKLDNILLHTPEPCTKVVLADFGI-AKELSQNTKERMHTVVGTPEYCAPEVGF 320
+GI HRD+K N+LL + + ++DFG+ A ++ +HT GTP Y APEV
Sbjct: 139 DGIAHRDVKPQNLLL---DKQGNLKVSDFGLSALPEHRSNNGLLHTACGTPAYTAPEV-- 193
Query: 321 KADRNIYRSFSRTATLDPDNNGYD-SKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNV 379
GYD +K D WS GV ++L G PF +A+I+
Sbjct: 194 -----------------IAQRGYDGAKADAWSCGVFLFVLLAGYVPF----DDANIVAMY 232
Query: 380 R-TGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKHTS-------- 430
R K ++ W I+ A+S + K L + R +E + VW +K
Sbjct: 233 RKIHKRDYRFPSW--ISKPARSIIYKLLDPNPETRMSIEAVMGTVWFQKSLEISEFQSSV 290
Query: 431 -QLERIYKKKVLQLSS----DCIKIDENIDTFAVVKHKLPKSVKLS 471
+L+R +K+ ++ D I + +D + + + K + +
Sbjct: 291 FELDRFLEKEAKSSNAITAFDLISLSSGLDLSGLFERRKRKEKRFT 336
>At3g20410 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 541
Score = 106 bits (265), Expect = 7e-23
Identities = 87/325 (26%), Positives = 149/325 (45%), Gaps = 43/325 (13%)
Query: 145 VGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKLN-HPNIIR 203
+G G FG + +++ ++ A K++S V K M +E I++ L+ PNI+
Sbjct: 97 LGRGQFGVTYLC--TENSTGKKYACKSISKKKLVTKADKDDMRREIQIMQHLSGQPNIVE 154
Query: 204 IHQSCVDALGNVYIFQDLISGGDLFS-YLAKGDCLVPISETESLIIIYQILLALKFLHSN 262
+ D V + +L +GG+LF +AKG +E + + QI+ +K H
Sbjct: 155 FKGAYEDEKA-VNLVMELCAGGELFDRIIAKGH----YTERAAASVCRQIVNVVKICHFM 209
Query: 263 GIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKA 322
G++HRDLK +N LL + + + DFG++ + + R +VG+ Y APEV
Sbjct: 210 GVLHRDLKPENFLLSSKDEKALIKATDFGLSVFIEEGKVYR--DIVGSAYYVAPEV---- 263
Query: 323 DRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVRTG 382
Y + DIWS G+I +I+L+G+ PF+ + +E I + G
Sbjct: 264 ----------------LRRRYGKEVDIWSAGIILYILLSGVPPFWAE-TEKGIFDAILEG 306
Query: 383 KLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKHTSQLERIYKKKVL- 441
++F ++ W +I+ SAK V++ L R + L W+ + ++ VL
Sbjct: 307 HIDFESQPWPSISSSAKDLVRRMLTADPKRRISAADVLQHPWLREGGEASDKPIDSAVLS 366
Query: 442 ---------QLSSDCIK-IDENIDT 456
+L +K I ENIDT
Sbjct: 367 RMKQFRAMNKLKKLALKVIAENIDT 391
>YGL158w [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 512
Score = 106 bits (264), Expect = 9e-23
Identities = 99/369 (26%), Positives = 167/369 (44%), Gaps = 82/369 (22%)
Query: 134 EWDRWKIVPRIVGSGTFGHVLVAEKVDHNMKRQVAKKTV------SYAV-----KVINTA 182
E +K++ +I G G F V A ++ + + VA K + S A+ ++ ++
Sbjct: 117 ELHNYKLLNKI-GEGAFSRVFKAVGINTDDQAPVAIKAIIKKGISSDAILKGNDRIQGSS 175
Query: 183 KTRMVKEATI--LEKLNHPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPI 240
+ +++ E I L N+P+ + + ++ Y+ +L++GG++F + + C
Sbjct: 176 RKKVLNEVAIHKLVSKNNPHCTKFI-AFQESANYYYLVTELVTGGEIFDRIVQLTCF--- 231
Query: 241 SETESLIIIYQILLALKFLHSNGIVHRDLKLDNILLHTPEP------------------- 281
SE + +I Q+ +A+K +H GIVHRD+K +N+L P P
Sbjct: 232 SEDLARHVITQVAIAIKHMHYMGIVHRDVKPENLLFE-PIPFYGLDGDMQKEDEFTLGVG 290
Query: 282 ---CTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKADRNIYRSFSRTATLDP 338
V L DFG+AK+L NT + T GT EY A EV F + R
Sbjct: 291 GGGIGLVKLMDFGLAKKLRNNTAK---TPCGTIEYVASEV-FTSKR-------------- 332
Query: 339 DNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVRTGKLNFTARQWIAITDSA 398
Y K D+WS+G + +L G PFY + +E +++K + G F A W I+ A
Sbjct: 333 ----YSMKVDMWSIGCVLFTLLCGYPPFY-EKNEKTLLKKISRGDYEFLAPWWDNISSGA 387
Query: 399 KSFVKKCLQVSTFNRCDVEEALHQVWVEKHTSQLERIYKKKVLQLSSDCIKIDENIDTFA 458
K+ V L+V R D+++ L+ W+ S DC+K D N +++A
Sbjct: 388 KNAVTHLLEVDPNKRYDIDDFLNDPWLN-----------------SYDCLK-DSNSNSYA 429
Query: 459 VVKHKLPKS 467
V+ L S
Sbjct: 430 SVQSILNDS 438
>Hs4506737 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 525
Score = 106 bits (264), Expect = 9e-23
Identities = 86/273 (31%), Positives = 133/273 (48%), Gaps = 34/273 (12%)
Query: 143 RIVGSGTFGHVLVAEKVDH-NMKRQVAKKTVSYAVKVINTAKTRMVK-EATILEKLNHPN 200
R++G G +G V KV N + A K + A+ V N T K E ILE++ HP
Sbjct: 95 RVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTKAERNILEEVKHPF 154
Query: 201 IIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLH 260
I+ + + G +Y+ + +SGG+LF L + + E + + +I +AL LH
Sbjct: 155 IVDLIYAFQTG-GKLYLILEYLSGGELFMQLEREGIFM---EDTACFYLAEISMALGHLH 210
Query: 261 SNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGF 320
GI++RDLK +NI+L+ V L DFG+ KE S + HT GT EY APE+
Sbjct: 211 QKGIIYRDLKPENIMLNHQG---HVKLTDFGLCKE-SIHDGTVTHTFCGTIEYMAPEILM 266
Query: 321 KADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVR 380
++ G++ D WSLG + + MLTG PF G+ + +I K ++
Sbjct: 267 RS-------------------GHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILK 307
Query: 381 TGKLNFTARQWIAITDSAKSFVKKCLQVSTFNR 413
KLN +T A+ +KK L+ + +R
Sbjct: 308 C-KLNLPP----YLTQEARDLLKKLLKRNAASR 335
>At4g04740 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 520
Score = 106 bits (264), Expect = 9e-23
Identities = 72/240 (30%), Positives = 118/240 (49%), Gaps = 30/240 (12%)
Query: 189 EATILEKLN-HPNIIRIHQSCVDALGNVYIFQDLISGGDLFS-YLAKGDCLVPISETESL 246
E I++ L+ PN++ I S D +V++ +L +GG+LF +A+G SE +
Sbjct: 117 EIQIMQHLSGQPNVVEIKGSYEDR-HSVHLVMELCAGGELFDRIIAQGH----YSERAAA 171
Query: 247 IIIYQILLALKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHT 306
I I+ ++ H NG++HRDLK +N L + E + + DFG++ + + +
Sbjct: 172 GTIKSIVDVVQICHLNGVIHRDLKPENFLFSSKEENAMLKVTDFGLSAFIEEGKIYK--D 229
Query: 307 VVGTPEYCAPEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPF 366
VVG+P Y APEV Y + DIWS GVI +I+L G+ PF
Sbjct: 230 VVGSPYYVAPEVL--------------------RQSYGKEIDIWSAGVILYILLCGVPPF 269
Query: 367 YGDGSEASIIKNVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVE 426
+ D E ++ ++ K++F W +I+DSAK V+K L R + L W++
Sbjct: 270 WADNEEGVFVEILKC-KIDFVREPWPSISDSAKDLVEKMLTEDPKRRITAAQVLEHPWIK 328
>Hs5032091 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 431
Score = 105 bits (263), Expect = 1e-22
Identities = 89/289 (30%), Positives = 133/289 (45%), Gaps = 49/289 (16%)
Query: 143 RIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEA--------TILE 194
+++G G+FG VL+A R A++ V YAVKV+ KE +L+
Sbjct: 102 KVIGKGSFGKVLLA--------RHKAEE-VFYAVKVLQKKAILKKKEEKHIMSERNVLLK 152
Query: 195 KLNHPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILL 254
+ HP ++ +H S A +Y D I+GG+LF +L + C + E + +I
Sbjct: 153 NVKHPFLVGLHFSFQTA-DKLYFVLDYINGGELFYHLQRERCFL---EPRARFYAAEIAS 208
Query: 255 ALKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYC 314
AL +LHS IV+RDLK +NILL + +VL DFG+ KE ++ T GTPEY
Sbjct: 209 ALGYLHSLNIVYRDLKPENILLDSQ---GHIVLTDFGLCKENIEH-NSTTSTFCGTPEYL 264
Query: 315 APEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEAS 374
APEV K YD D W LG + + ML G+ PFY + A
Sbjct: 265 APEVLHK-------------------QPYDRTVDWWCLGAVLYEMLYGLPPFYSRNT-AE 304
Query: 375 IIKNVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQV 423
+ N+ L IT+SA+ ++ LQ R ++ ++
Sbjct: 305 MYDNILNKPLQLKPN----ITNSARHLLEGLLQKDRTKRLGAKDDFMEI 349
>Hs4506057 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 351
Score = 105 bits (263), Expect = 1e-22
Identities = 84/308 (27%), Positives = 148/308 (47%), Gaps = 54/308 (17%)
Query: 143 RIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVK-------EATILEK 195
+ +G+G+FG V++ V H Q YA+K+++ K +K E IL+
Sbjct: 48 KTLGTGSFGRVML---VKHKATEQY------YAMKILDKQKVVKLKQIEHTLNEKRILQA 98
Query: 196 LNHPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLA 255
+N P ++R+ + D N+Y+ + + GG++FS+L + + SE + QI+L
Sbjct: 99 VNFPFLVRLEYAFKDN-SNLYMVMEYVPGGEMFSHLRR---IGRFSEPHARFYAAQIVLT 154
Query: 256 LKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCA 315
++LHS +++RDLK +N+L+ + + + DFG AK + K R T+ GTPEY A
Sbjct: 155 FEYLHSLDLIYRDLKPENLLI---DHQGYIQVTDFGFAKRV----KGRTWTLCGTPEYLA 207
Query: 316 PEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASI 375
PE+ + GY+ D W+LGV+ + M G PF+ D I
Sbjct: 208 PEIIL-------------------SKGYNKAVDWWALGVLIYEMAAGYPPFFAD-QPIQI 247
Query: 376 IKNVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRC-DVEEALHQVWVEK--HTSQL 432
+ + +GK+ F + + K ++ LQV R +++ + + K T+
Sbjct: 248 YEKIVSGKVRFPSH----FSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDW 303
Query: 433 ERIYKKKV 440
IY++KV
Sbjct: 304 IAIYQRKV 311
>CE15475 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 375
Score = 105 bits (263), Expect = 1e-22
Identities = 81/278 (29%), Positives = 135/278 (48%), Gaps = 51/278 (18%)
Query: 143 RIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVK-------EATILEK 195
+ +G+G+FG V++ V H YA+K+++ K +K E IL+
Sbjct: 56 KTLGTGSFGRVML---VKHKQSGNY------YAMKILDKQKVVKLKQVEHTLNEKRILQA 106
Query: 196 LNHPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLA 255
++ P ++ + S D N+Y+ + ISGG++FS+L + + SE S QI+LA
Sbjct: 107 IDFPFLVNMTFSFKDN-SNLYMVLEFISGGEMFSHLRR---IGRFSEPHSRFYAAQIVLA 162
Query: 256 LKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCA 315
++LHS +++RDLK +N+L+ + + + DFG AK + K R T+ GTPEY A
Sbjct: 163 FEYLHSLDLIYRDLKPENLLI---DSTGYLKITDFGFAKRV----KGRTWTLCGTPEYLA 215
Query: 316 PEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASI 375
PE+ + GY+ D W+LGV+ + M G PF+ D I
Sbjct: 216 PEIIL-------------------SKGYNKAVDWWALGVLIYEMAAGYPPFFAD-QPIQI 255
Query: 376 IKNVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNR 413
+ + +GK+ F + ++ K +K LQV R
Sbjct: 256 YEKIVSGKVKFPSH----FSNELKDLLKNLLQVDLTKR 289
>CE15473 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 359
Score = 105 bits (263), Expect = 1e-22
Identities = 81/278 (29%), Positives = 135/278 (48%), Gaps = 51/278 (18%)
Query: 143 RIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVK-------EATILEK 195
+ +G+G+FG V++ V H YA+K+++ K +K E IL+
Sbjct: 56 KTLGTGSFGRVML---VKHKQSGNY------YAMKILDKQKVVKLKQVEHTLNEKRILQA 106
Query: 196 LNHPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLA 255
++ P ++ + S D N+Y+ + ISGG++FS+L + + SE S QI+LA
Sbjct: 107 IDFPFLVNMTFSFKDN-SNLYMVLEFISGGEMFSHLRR---IGRFSEPHSRFYAAQIVLA 162
Query: 256 LKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCA 315
++LHS +++RDLK +N+L+ + + + DFG AK + K R T+ GTPEY A
Sbjct: 163 FEYLHSLDLIYRDLKPENLLI---DSTGYLKITDFGFAKRV----KGRTWTLCGTPEYLA 215
Query: 316 PEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASI 375
PE+ + GY+ D W+LGV+ + M G PF+ D I
Sbjct: 216 PEIIL-------------------SKGYNKAVDWWALGVLIYEMAAGYPPFFAD-QPIQI 255
Query: 376 IKNVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNR 413
+ + +GK+ F + ++ K +K LQV R
Sbjct: 256 YEKIVSGKVKFPSH----FSNELKDLLKNLLQVDLTKR 289
>At5g45810 [T] KOG0583 Serine/threonine protein kinase
Length = 483
Score = 105 bits (263), Expect = 1e-22
Identities = 80/294 (27%), Positives = 139/294 (47%), Gaps = 50/294 (17%)
Query: 143 RIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKT-------RMVKEATILEK 195
R++G GTF V +A A+ S A+KVI+ K + +E +IL +
Sbjct: 32 RLLGHGTFAKVYLARN---------AQSGESVAIKVIDKEKVLKSGLIAHIKREISILRR 82
Query: 196 LNHPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLA 255
+ HPNI+++ + + +Y + + GG+LF+ +AKG + E + Q++ A
Sbjct: 83 VRHPNIVQLFE-VMATKSKIYFVMEYVKGGELFNKVAKGR----LKEEMARKYFQQLISA 137
Query: 256 LKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERM-HTVVGTPEYC 314
+ F H G+ HRDLK +N+LL + + ++DFG++ Q ++ + HT GTP Y
Sbjct: 138 VSFCHFRGVYHRDLKPENLLL---DENGNLKVSDFGLSAVSDQIRQDGLFHTFCGTPAYV 194
Query: 315 APEVGFKADRNIYRSFSRTATLDPDNNGYD-SKCDIWSLGVITHIMLTGISPFYGDGSEA 373
APEV + GYD +K DIWS GVI +++ G PF+ D +
Sbjct: 195 APEVLAR-------------------KGYDGAKVDIWSCGVILFVLMAGFLPFH-DRNVM 234
Query: 374 SIIKNVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEK 427
++ K + G +F +W + + + L+ R + + + W +K
Sbjct: 235 AMYKKIYRG--DFRCPRWFPV--EINRLLIRMLETKPERRFTMPDIMETSWFKK 284
>At5g19450 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 533
Score = 105 bits (263), Expect = 1e-22
Identities = 86/324 (26%), Positives = 149/324 (45%), Gaps = 48/324 (14%)
Query: 108 NGAKFKFSAVKSETMSQFMTGLRIKSEWDRWKIVPRIVGSGTFGHVLVAEKVDHNMK--- 164
+G FK S +K T G I +D + R VG G FG + + K
Sbjct: 36 SGTGFKLSVLKDPT------GHDISLMYD----LGREVGRGEFGITYLCTDIKTGEKYAC 85
Query: 165 RQVAKKTVSYAVKVINTAKTRMVKEATILEKL-NHPNIIRIHQSCVDALGNVYIFQDLIS 223
+ ++KK + AV + + + E I++ + HPNI+ + + D V+I +L
Sbjct: 86 KSISKKKLRTAVDIEDVRR-----EVEIMKHMPRHPNIVSLKDAFEDD-DAVHIVMELCE 139
Query: 224 GGDLFSYL-AKGDCLVPISETESLIIIYQILLALKFLHSNGIVHRDLKLDNILLHTPEPC 282
GG+LF + A+G +E + ++ IL ++ H +G++HRDLK +N L +
Sbjct: 140 GGELFDRIVARGH----YTERAAAAVMKTILEVVQICHKHGVMHRDLKPENFLFANKKET 195
Query: 283 TKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKADRNIYRSFSRTATLDPDNNG 342
+ + DFG++ E + +VG+P Y APEV RN
Sbjct: 196 SALKAIDFGLSVFFKPG--EGFNEIVGSPYYMAPEV---LRRN----------------- 233
Query: 343 YDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVRTGKLNFTARQWIAITDSAKSFV 402
Y + DIWS GVI +I+L G+ PF+ + +E + + + ++F W ++++AK V
Sbjct: 234 YGPEVDIWSAGVILYILLCGVPPFWAE-TEQGVAQAIIRSVIDFKRDPWPRVSETAKDLV 292
Query: 403 KKCLQVSTFNRCDVEEALHQVWVE 426
+K L+ R + L W++
Sbjct: 293 RKMLEPDPKKRLSAAQVLEHSWIQ 316
>At5g07070 [T] KOG0583 Serine/threonine protein kinase
Length = 456
Score = 105 bits (263), Expect = 1e-22
Identities = 83/313 (26%), Positives = 149/313 (47%), Gaps = 44/313 (14%)
Query: 141 VPRIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVK-EATILEKLNHP 199
V R++G GTF V ++ VA K + KV+ ++ +K E +++ HP
Sbjct: 14 VGRLLGQGTFAKVYFGRS--NHTNESVAIKMIDKD-KVMRVGLSQQIKREISVMRIAKHP 70
Query: 200 NIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFL 259
N++ +++ + +Y + GG+LF+ +AKG + E + YQ++ A+ F
Sbjct: 71 NVVELYE-VMATKSRIYFVIEYCKGGELFNKVAKGK----LKEDVAWKYFYQLISAVDFC 125
Query: 260 HSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKE-RMHTVVGTPEYCAPEV 318
HS G+ HRD+K +N+LL + + ++DFG++ ++ +HT GTP Y APEV
Sbjct: 126 HSRGVYHRDIKPENLLLDDND---NLKVSDFGLSALADCKRQDGLLHTTCGTPAYVAPEV 182
Query: 319 GFKADRNIYRSFSRTATLDPDNNGYD-SKCDIWSLGVITHIMLTGISPFYGDGSEASIIK 377
+ GY+ +K DIWS GV+ ++L G PF+ + ++++
Sbjct: 183 -------------------INRKGYEGTKADIWSCGVVLFVLLAGYLPFH----DTNLME 219
Query: 378 NVR-TGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEK--HTSQ--L 432
R GK +F W A K + K L + R + + W K H Q +
Sbjct: 220 MYRKIGKADFKCPSWFA--PEVKRLLCKMLDPNHETRITIAKIKESSWFRKGLHLKQKKM 277
Query: 433 ERIYKKKVLQLSS 445
E++ K++V + ++
Sbjct: 278 EKMEKQQVREATN 290
>SPAC1B9.02c [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 696
Score = 105 bits (262), Expect = 2e-22
Identities = 84/268 (31%), Positives = 132/268 (48%), Gaps = 37/268 (13%)
Query: 143 RIVGSGTFGHVLVAEKVDHNM---KRQVAKKTVSYAVKVINTAKTRMVKEATILEKLNHP 199
R++G GTFG V + K D N ++++KK + +V +T R + T L++ P
Sbjct: 306 RLIGKGTFGQVYLVRKNDTNRIYAMKKISKKLIVRKKEVTHTLGERNILVRTSLDE--SP 363
Query: 200 NIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFL 259
I+ + S A ++Y+ D +SGG+LF +L E + I +++LAL+ L
Sbjct: 364 FIVGLKFSFQTA-SDLYLITDYMSGGELFWHLQHEG---RFPEQRAKFYIAELVLALEHL 419
Query: 260 HSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAK-ELSQNTKERMHTVVGTPEYCAPEV 318
H + I++RDLK +NILL + + L DFG++K LS N +T GT EY APEV
Sbjct: 420 HKHDIIYRDLKPENILL---DADGHIALCDFGLSKANLSANA--TTNTFCGTTEYLAPEV 474
Query: 319 GFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKN 378
++ GY + D WSLGV+ M G SPFY + + +N
Sbjct: 475 LL------------------EDKGYTKQVDFWSLGVLVFEMCCGWSPFYAPDVQ-QMYRN 515
Query: 379 VRTGKLNFTARQWIAITDSAKSFVKKCL 406
+ GK+ F ++ +SFV+ L
Sbjct: 516 IAFGKVRFPKG---VLSSEGRSFVRGLL 540
>Hs8923922 [R] KOG0586 Serine/threonine protein kinase
Length = 795
Score = 105 bits (262), Expect = 2e-22
Identities = 79/284 (27%), Positives = 140/284 (48%), Gaps = 37/284 (13%)
Query: 143 RIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKLNHPNII 202
+ +G G F V +A V R+VA K + ++ T+ ++ +E I++ LNHPNI+
Sbjct: 64 KTIGKGNFAKVKLARHVLTG--REVAVKIID-KTQLNPTSLQKLFREVRIMKILNHPNIV 120
Query: 203 RIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHSN 262
++ + ++ +Y+ + SGG++F YL + E E+ QI+ A+++ H
Sbjct: 121 KLFE-VIETEKTLYLVMEYASGGEVFDYLVAHGRM---KEKEARAKFRQIVSAVQYCHQK 176
Query: 263 GIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKA 322
IVHRDLK +N+LL + + +ADFG + E + K + T G+P Y APE+ F+
Sbjct: 177 YIVHRDLKAENLLL---DGDMNIKIADFGFSNEFTVGNK--LDTFCGSPPYAAPEL-FQG 230
Query: 323 DRNIYRSFSRTATLDPDNNGYDS-KCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVRT 381
+ YD + D+WSLGVI + +++G PF G +K +R
Sbjct: 231 KK------------------YDGPEVDVWSLGVILYTLVSGSLPFDGQN-----LKELRE 267
Query: 382 GKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWV 425
L R ++ ++ +KK L ++ R +E+ + W+
Sbjct: 268 RVLRGKYRIPFYMSTDCENLLKKLLVLNPIKRGSLEQIMKDRWM 311
>Hs10835065 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 277
Score = 105 bits (262), Expect = 2e-22
Identities = 80/243 (32%), Positives = 123/243 (49%), Gaps = 35/243 (14%)
Query: 145 VGSGTFGHV-LVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKLNHPNIIR 203
+G+GTFG V LV EK K A K +S + + + E ++L++++HP +IR
Sbjct: 55 MGTGTFGRVHLVKEKT---AKHFFALKVMSIPDVIRRKQEQHVHNEKSVLKEVSHPFLIR 111
Query: 204 IHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHSNG 263
+ + + +Y+ + + GG+LFSYL S T L +I+ A+++LHS
Sbjct: 112 LFWTWHEERF-LYMLMEYVPGGELFSYLRNRG---HFSSTTGLFYSAEIICAIEYLHSKE 167
Query: 264 IVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKAD 323
IV+RDLK +NILL + + L DFG AK+L +R T+ GTPEY APEV
Sbjct: 168 IVYRDLKPENILL---DRDGHIKLTDFGFAKKL----VDRTWTLCGTPEYLAPEV----- 215
Query: 324 RNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVRTGK 383
+ G+ D W+LG++ ML+G PF+ D + I + + GK
Sbjct: 216 --------------IQSKGHGRAVDWWALGILIFEMLSGFPPFF-DDNPFGIYQKILAGK 260
Query: 384 LNF 386
L F
Sbjct: 261 LYF 263
>CE27768 [R] KOG0586 Serine/threonine protein kinase
Length = 1096
Score = 105 bits (262), Expect = 2e-22
Identities = 78/286 (27%), Positives = 141/286 (49%), Gaps = 41/286 (14%)
Query: 143 RIVGSGTFGHVLVAEKV--DHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKLNHPN 200
+ +G G F V +A+ V H + ++ KT + ++ ++ +E I+++L+HPN
Sbjct: 126 KTIGKGNFAKVKLAKHVITGHEVAIKIIDKTA-----LNPSSLQKLFREVKIMKQLDHPN 180
Query: 201 IIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLH 260
I++++Q ++ +Y+ + SGG++F YL + E E+ QI+ A+++LH
Sbjct: 181 IVKLYQ-VMETEQTLYLVLEYASGGEVFDYLVAHGRM---KEKEARAKFRQIVSAVQYLH 236
Query: 261 SNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGF 320
S I+HRDLK +N+LL + + +ADFG + S K + T G+P Y APE+
Sbjct: 237 SKNIIHRDLKAENLLL---DQDMNIKIADFGFSNTFSLGNK--LDTFCGSPPYAAPEL-- 289
Query: 321 KADRNIYRSFSRTATLDPDNNGYDS-KCDIWSLGVITHIMLTGISPFYGDGSEASIIKNV 379
FS YD + D+WSLGVI + +++G PF G +K +
Sbjct: 290 ---------FS--------GKKYDGPEVDVWSLGVILYTLVSGSLPFDGQN-----LKEL 327
Query: 380 RTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWV 425
R L R ++ ++ +KK L ++ R ++ + W+
Sbjct: 328 RERVLRGKYRIPFYMSTDCENLLKKFLVINPQRRSSLDNIMKDRWM 373
>CE23838 [R] KOG0586 Serine/threonine protein kinase
Length = 1192
Score = 105 bits (262), Expect = 2e-22
Identities = 78/286 (27%), Positives = 141/286 (49%), Gaps = 41/286 (14%)
Query: 143 RIVGSGTFGHVLVAEKV--DHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKLNHPN 200
+ +G G F V +A+ V H + ++ KT + ++ ++ +E I+++L+HPN
Sbjct: 174 KTIGKGNFAKVKLAKHVITGHEVAIKIIDKTA-----LNPSSLQKLFREVKIMKQLDHPN 228
Query: 201 IIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLH 260
I++++Q ++ +Y+ + SGG++F YL + E E+ QI+ A+++LH
Sbjct: 229 IVKLYQ-VMETEQTLYLVLEYASGGEVFDYLVAHGRM---KEKEARAKFRQIVSAVQYLH 284
Query: 261 SNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGF 320
S I+HRDLK +N+LL + + +ADFG + S K + T G+P Y APE+
Sbjct: 285 SKNIIHRDLKAENLLL---DQDMNIKIADFGFSNTFSLGNK--LDTFCGSPPYAAPEL-- 337
Query: 321 KADRNIYRSFSRTATLDPDNNGYDS-KCDIWSLGVITHIMLTGISPFYGDGSEASIIKNV 379
FS YD + D+WSLGVI + +++G PF G +K +
Sbjct: 338 ---------FS--------GKKYDGPEVDVWSLGVILYTLVSGSLPFDGQN-----LKEL 375
Query: 380 RTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWV 425
R L R ++ ++ +KK L ++ R ++ + W+
Sbjct: 376 RERVLRGKYRIPFYMSTDCENLLKKFLVINPQRRSSLDNIMKDRWM 421
>CE21879 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 328
Score = 105 bits (262), Expect = 2e-22
Identities = 79/297 (26%), Positives = 147/297 (48%), Gaps = 35/297 (11%)
Query: 145 VGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKT---RMVKEATILEKLNHPNI 201
+G G FG V +AEK++ N + +VA K ++ + K ++ +E I + + H NI
Sbjct: 12 IGKGAFGQVFLAEKLN-NPRIKVAMKKIN----IFGAPKEFLEQIQQEYYIQKNMKHKNI 66
Query: 202 IRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHS 261
++++ +D Y+FQ+ ++GGDLF + + + P+++ + + Q++ LK++H
Sbjct: 67 VKMYGMSMDT-EFCYLFQEFVTGGDLFEKIDFENGM-PVNQVKGYL--KQLMSGLKYIHG 122
Query: 262 NGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKE-RMHTVVGTPEYCAPEVGF 320
GIVHRD+K DN+L+++ + + +ADFG++ + KE +H +GT + APE+
Sbjct: 123 CGIVHRDIKPDNLLINSSD---ALKIADFGLSTRFIVDDKEILLHERIGTTPFMAPEL-- 177
Query: 321 KADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVR 380
F++ P DIWS G++ +LTG P + + E+ I+ +
Sbjct: 178 ---------FAKKKHRGP-------PVDIWSAGILVFSLLTGNLP-WDEPKESDILYSQW 220
Query: 381 TGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKHTSQLERIYK 437
W ++ F+KK L+ + R +EE W+E + E K
Sbjct: 221 MNNKTSKNCIWYGLSTPVVRFLKKLLKENVNERATIEEIESDPWLEDLEEERENCTK 277
>7290249 [R] KOG0586 Serine/threonine protein kinase
Length = 1398
Score = 105 bits (262), Expect = 2e-22
Identities = 78/286 (27%), Positives = 142/286 (49%), Gaps = 37/286 (12%)
Query: 141 VPRIVGSGTFGHVLVAEKVDHNM-KRQVAKKTVSYAVKVINTAKTRMVKEATILEKLNHP 199
+ R +G G F V +A H + K +VA K + + ++ T ++ +E I+++L HP
Sbjct: 143 IERTIGKGNFAVVKLAR---HRITKNEVAIKIIDKS-QLDQTNLQKVYREVEIMKRLKHP 198
Query: 200 NIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFL 259
+II+++Q ++ +YI + S G++F Y+AK + SE+ + +QI+ A+++
Sbjct: 199 HIIKLYQ-VMETKNMIYIVSEYASQGEIFDYIAKYGRM---SESAARFKFWQIISAVEYC 254
Query: 260 HSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVG 319
H GIVHRDLK +N+LL + + +ADFG + E + T G+P Y APEV
Sbjct: 255 HKKGIVHRDLKAENLLL---DLNMNIKIADFGFSNHFKPG--ELLATWCGSPPYAAPEV- 308
Query: 320 FKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNV 379
F P+ DIWSLGV+ ++++ G PF G S ++++
Sbjct: 309 ----------FEGKQYTGPE-------IDIWSLGVVLYVLVCGALPFDG-----STLQSL 346
Query: 380 RTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWV 425
R L+ R ++ + +++ L + R +++ W+
Sbjct: 347 RDRVLSGRFRIPFFMSSECEHLIRRMLVLEPTRRYTIDQIKRHRWM 392
>At1g50700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 521
Score = 105 bits (261), Expect = 2e-22
Identities = 88/325 (27%), Positives = 149/325 (45%), Gaps = 43/325 (13%)
Query: 145 VGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKLN-HPNIIR 203
+G G FG + + + ++ A K++S V K M +E I++ L+ PNI+
Sbjct: 79 LGRGQFGVTYLC--TEKSTGKRFACKSISKKKLVTKGDKEDMRREIQIMQHLSGQPNIVE 136
Query: 204 IHQSCVDALGNVYIFQDLISGGDLFS-YLAKGDCLVPISETESLIIIYQILLALKFLHSN 262
+ D V + +L +GG+LF LAKG SE + + QI+ + H
Sbjct: 137 FKGAYEDEKA-VNLVMELCAGGELFDRILAKGH----YSERAAASVCRQIVNVVNICHFM 191
Query: 263 GIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKA 322
G++HRDLK +N LL + + + DFG++ + + + +VG+ Y APEV
Sbjct: 192 GVMHRDLKPENFLLSSKDEKALIKATDFGLSVFIEEGRVYK--DIVGSAYYVAPEV---- 245
Query: 323 DRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVRTG 382
Y + DIWS G+I +I+L+G+ PF+ + +E I + G
Sbjct: 246 ----------------LKRRYGKEIDIWSAGIILYILLSGVPPFWAE-TEKGIFDAILEG 288
Query: 383 KLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKHTSQLERIYKKKVL- 441
+++F ++ W +I++SAK V++ L R E L W+ + ++ VL
Sbjct: 289 EIDFESQPWPSISNSAKDLVRRMLTQDPKRRISAAEVLKHPWLREGGEASDKPIDSAVLS 348
Query: 442 ---------QLSSDCIK-IDENIDT 456
+L +K I ENIDT
Sbjct: 349 RMKQFRAMNKLKKLALKVIAENIDT 373
>Hs13899225 [R] KOG0586 Serine/threonine protein kinase
Length = 688
Score = 104 bits (260), Expect = 3e-22
Identities = 77/284 (27%), Positives = 138/284 (48%), Gaps = 37/284 (13%)
Query: 143 RIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKLNHPNII 202
R +G G V +A + R+VA K + ++ ++ ++ +E I++ LNHPNI+
Sbjct: 63 RTIGKGNSAKVKLARHILTG--REVAIKIID-KTQLNPSSLQKLFREVRIMKGLNHPNIV 119
Query: 203 RIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHSN 262
++ + ++ +Y+ + S G++F YL + E E+ QI+ A+ + H
Sbjct: 120 KLFE-VIETEKTLYLVMEYASAGEVFDYLVSHGRM---KEKEARAKFRQIVSAVHYCHQK 175
Query: 263 GIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKA 322
IVHRDLK +N+LL + +ADFG + E + +K + T G+P Y APE+ F+
Sbjct: 176 NIVHRDLKAENLLLDAE---ANIKIADFGFSNEFTLGSK--LDTFCGSPPYAAPEL-FQG 229
Query: 323 DRNIYRSFSRTATLDPDNNGYDS-KCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVRT 381
+ YD + DIWSLGVI + +++G PF G +K +R
Sbjct: 230 KK------------------YDGPEVDIWSLGVILYTLVSGSLPFDGHN-----LKELRE 266
Query: 382 GKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWV 425
L R ++ +S +++ L ++ RC +E+ + W+
Sbjct: 267 RVLRGKYRVPFYMSTDCESILRRFLVLNPAKRCTLEQIMKDKWI 310
>CE05780 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 336
Score = 104 bits (260), Expect = 3e-22
Identities = 83/328 (25%), Positives = 142/328 (42%), Gaps = 50/328 (15%)
Query: 120 ETMSQFMTGLRIKSEWDRWKIVPRIVGSGTFGHVLVAEKVDHNMK-----RQVAKKTVSY 174
E +S+++ + + + ++ + I+G G F V + + + K R + S+
Sbjct: 38 ENVSKWIQRVDGRQDIEKQYEIGAIIGKGNFSSVHLTRRKEDGTKCALKVRYQSTLQFSF 97
Query: 175 AVKVINTAKTRMVK--------EATILEKLNHPNIIRIHQSCVDALGN---VYIFQDLIS 223
K + R ++ E +L + H +II I +DA +I +
Sbjct: 98 PSKFFQQVEKRAMRGKCFFVDNEVEMLSLIQHDHIISI----IDAFSTENQYFIVFEHAQ 153
Query: 224 GGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHSNGIVHRDLKLDNILLHTPEPCT 283
GDL+ + K I E ++ II Q+ AL +LH +VHRD+K +N+LL
Sbjct: 154 YGDLYETIRKNG---RIEEPDAAIITLQVASALNYLHERNVVHRDVKPENLLLVDK---F 207
Query: 284 KVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKADRNIYRSFSRTATLDPDNNGY 343
V L DFG+A + ++ + GTP YCAPEV GY
Sbjct: 208 SVKLCDFGLACHILGP----LYRICGTPTYCAPEV-------------------LRETGY 244
Query: 344 DSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVRTGKLNFTARQWIAITDSAKSFVK 403
++CDIWSLGV+ ++ML G +PF + + K + K N +W I+ AK V
Sbjct: 245 STRCDIWSLGVVLYVMLVGYAPFRAP-DQTRLFKLIMQAKPNLDMPEWKGISLKAKDLVS 303
Query: 404 KCLQVSTFNRCDVEEALHQVWVEKHTSQ 431
+ + + R + + W+ +T +
Sbjct: 304 RLMNKTEERRPLASQIMAHPWIAPYTME 331
>Hs4507831 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 1050
Score = 104 bits (259), Expect = 3e-22
Identities = 92/301 (30%), Positives = 138/301 (45%), Gaps = 52/301 (17%)
Query: 144 IVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINT-----AKTRMVKEATILEKLNH 198
++G G F V R K + AVK IN ++T + KE IL++L H
Sbjct: 21 LIGHGAFAVVFKG--------RHREKHDLEVAVKCINKKNLAKSQTLLGKEIKILKELKH 72
Query: 199 PNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKF 258
NI+ ++ + +VY+ + +GGDL YL + +SE + + QI A++
Sbjct: 73 ENIVALYDF-QEMANSVYLVMEYCNGGDLADYL---HAMRTLSEDTIRLFLQQIAGAMRL 128
Query: 259 LHSNGIVHRDLKLDNILLHTP------EPCTKVVLADFGIAKELSQNTKERMHTVVGTPE 312
LHS GI+HRDLK NILL P +V +ADFG A+ L N T+ G+P
Sbjct: 129 LHSKGIIHRDLKPQNILLSNPAGRRANPNSIRVKIADFGFARYLQSNMMAA--TLCGSPM 186
Query: 313 YCAPEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSE 372
Y APEV + YD K D+WS+G I + LTG +PF +
Sbjct: 187 YMAPEVIM-------------------SQHYDGKADLWSIGTIVYQCLTGKAPF-----Q 222
Query: 373 ASIIKNVRT-GKLNFTARQWIAITDSA--KSFVKKCLQVSTFNRCDVEEALHQVWVEKHT 429
AS +++R + N T I SA + + LQ + +R D +E H +++
Sbjct: 223 ASSPQDLRLFYEKNKTLVPTIPRETSAPLRQLLLALLQRNHKDRMDFDEFFHHPFLDASP 282
Query: 430 S 430
S
Sbjct: 283 S 283
>At1g08650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 284
Score = 104 bits (259), Expect = 3e-22
Identities = 74/238 (31%), Positives = 107/238 (44%), Gaps = 29/238 (12%)
Query: 198 HPNIIRIHQSCVDALGNVYIFQDLISGG-DLFSYLAKGDCLVPISETESLIIIYQILLAL 256
HPNI++IH +D + IF +L+ ++ L E ++ QIL AL
Sbjct: 73 HPNIVQIHD-LIDTDSTLSIFMELVHPSVSIYDRLVSSGTFF---EPQTASFAKQILQAL 128
Query: 257 KFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAP 316
H G+VHRD+K +NIL+ K+ DFG L + E VVGTP Y AP
Sbjct: 129 SHCHRYGVVHRDIKPENILVDLRNDTVKI--CDFGSGIWLGEG--ETTEGVVGTPYYVAP 184
Query: 317 EVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASII 376
EV Y K D+WS GV+ + ML G PFYG+ +E I
Sbjct: 185 EVLM-------------------GYSYGEKVDLWSAGVVLYTMLAGTPPFYGETAE-EIF 224
Query: 377 KNVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKHTSQLER 434
+ V G L F + + ++ AK F++K + R E+AL W+++ ER
Sbjct: 225 EAVLRGNLRFPTKIFRGVSSMAKDFLRKLICKDASRRFSAEQALRHPWIQRAGETEER 282
>7290150 [T] KOG0583 Serine/threonine protein kinase
Length = 582
Score = 104 bits (259), Expect = 3e-22
Identities = 91/325 (28%), Positives = 150/325 (46%), Gaps = 59/325 (18%)
Query: 145 VGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMV-------KEATILEKLN 197
+G+GTFG V + E H + R V AVK++N K + + +E L+
Sbjct: 34 LGTGTFGKVKIGE---HQITR------VKVAVKILNRQKIKSLDVVGKIRREIQNLKLFR 84
Query: 198 HPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALK 257
HP+II+++Q + ++++ + +SGG+LF Y+ K L E ++ QI+ +
Sbjct: 85 HPHIIKLYQ-VISTPSDIFMIMEYVSGGELFDYIVKHGKL---QEHQARRFFQQIISGVD 140
Query: 258 FLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPE 317
+ H + IVHRDLK +N+LL + V +ADFG++ + E + T G+P Y APE
Sbjct: 141 YCHRHMIVHRDLKPENLLL---DHNMHVKIADFGLSNMMLDG--EFLRTSCGSPNYAAPE 195
Query: 318 VGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIK 377
V +Y + DIWS GVI + +L G PF D ++ +
Sbjct: 196 V---ISGKLYAG---------------PEVDIWSCGVILYALLCGTLPF-DDEHVPTLFR 236
Query: 378 NVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKHTSQLERIYK 437
+++G F ++ + + V + LQV R ++EE W +K
Sbjct: 237 KIKSG--IFPIPEY--LNKQVVNLVCQMLQVDPLKRANIEEIKKHEWFQKDLP------- 285
Query: 438 KKVLQLSSDCIKIDEN-IDTFAVVK 461
L I+ D N IDT+AV +
Sbjct: 286 ---AYLFPSSIEQDSNVIDTYAVAE 307
>Hs15619015 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 351
Score = 103 bits (258), Expect = 4e-22
Identities = 84/310 (27%), Positives = 145/310 (46%), Gaps = 58/310 (18%)
Query: 143 RIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVK-------EATILEK 195
R +G G+FG V++ + YA+K++N K +K E IL+
Sbjct: 48 RTLGMGSFGRVMLVRHQETGGH---------YAMKILNKQKVVKMKQVEHILNEKRILQA 98
Query: 196 LNHPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLA 255
++ P ++++ S D +Y+ + + GG++FS L + + SE + Q++LA
Sbjct: 99 IDFPFLVKLQFSFKDN-SYLYLVMEYVPGGEMFSRLQR---VGRFSEPHACFYAAQVVLA 154
Query: 256 LKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCA 315
+++LHS ++HRDLK +N+L+ + + + DFG AK + K R T+ GTPEY A
Sbjct: 155 VQYLHSLDLIHRDLKPENLLI---DQQGYLQVTDFGFAKRV----KGRTWTLCGTPEYLA 207
Query: 316 PEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASI 375
PE+ + GY+ D W+LGV+ + M G PFY D I
Sbjct: 208 PEIIL-------------------SKGYNKAVDWWALGVLIYEMAVGFPPFYAD-QPIQI 247
Query: 376 IKNVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRC-----DVEEALHQVWVEKHTS 430
+ + +G++ F ++ ++ K ++ LQV R V + + W T+
Sbjct: 248 YEKIVSGRVRFPSK----LSSDLKHLLRSLLQVDLTKRFGNLRNGVGDIKNHKWFA--TT 301
Query: 431 QLERIYKKKV 440
IY+KKV
Sbjct: 302 SWIAIYEKKV 311
>At5g25110 [T] KOG0583 Serine/threonine protein kinase
Length = 460
Score = 103 bits (258), Expect = 4e-22
Identities = 80/296 (27%), Positives = 136/296 (45%), Gaps = 52/296 (17%)
Query: 143 RIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTR-------MVKEATILEK 195
R++G GTFG V +++ S A+K+IN + + + +E +I+
Sbjct: 19 RLLGKGTFGKVYYGKEITTGE---------SVAIKIINKDQVKREGMMEQIKREISIMRL 69
Query: 196 LNHPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLA 255
+ HPNI+ + + ++ + + GG+LFS + KG + E + Q++ A
Sbjct: 70 VRHPNIVELKEVMATKT-KIFFIMEYVKGGELFSKIVKGK----LKEDSARKYFQQLISA 124
Query: 256 LKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKE-RMHTVVGTPEYC 314
+ F HS G+ HRDLK +N+L+ + + ++DFG++ Q ++ +HT GTP Y
Sbjct: 125 VDFCHSRGVSHRDLKPENLLV---DENGDLKVSDFGLSALPEQILQDGLLHTQCGTPAYV 181
Query: 315 APEVGFKADRNIYRSFSRTATLDPDNNGYD-SKCDIWSLGVITHIMLTGISPFYGDGSEA 373
APEV K GYD +K DIWS G+I +++L G PF +
Sbjct: 182 APEVLRK-------------------KGYDGAKGDIWSCGIILYVLLAGFLPF----QDE 218
Query: 374 SIIKNVR-TGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKH 428
+++K R K F W + +K + K L V R + + W K+
Sbjct: 219 NLMKMYRKIFKSEFEYPPW--FSPESKRLISKLLVVDPNKRISIPAIMRTPWFRKN 272
>At2g26980 [T] KOG0583 Serine/threonine protein kinase
Length = 441
Score = 103 bits (258), Expect = 4e-22
Identities = 74/290 (25%), Positives = 138/290 (47%), Gaps = 37/290 (12%)
Query: 141 VPRIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKLNHPN 200
V R +G GTF V A + VA K + + + ++ +E ++ + HPN
Sbjct: 16 VGRTIGEGTFAKVKFARNSETG--EPVALKILDKEKVLKHKMAEQIRREIATMKLIKHPN 73
Query: 201 IIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLH 260
++++++ ++I + ++GG+LF + + E E+ Q++ A+ + H
Sbjct: 74 VVQLYEVMASKT-KIFIILEYVTGGELFDKIVNDGRM---KEDEARRYFQQLIHAVDYCH 129
Query: 261 SNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKE--RMHTVVGTPEYCAPEV 318
S G+ HRDLK +N+LL + + ++DFG++ LSQ ++ +HT GTP Y APEV
Sbjct: 130 SRGVYHRDLKPENLLL---DSYGNLKISDFGLS-ALSQQVRDDGLLHTSCGTPNYVAPEV 185
Query: 319 GFKADRNIYRSFSRTATLDPDNNGYD-SKCDIWSLGVITHIMLTGISPFYGDGSEASIIK 377
++ GYD + D+WS GV+ +++L G PF D + ++ K
Sbjct: 186 -------------------LNDRGYDGATADMWSCGVVLYVLLAGYLPF-DDSNLMNLYK 225
Query: 378 NVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEK 427
+ +G+ F W+++ A + + L + R +E W +K
Sbjct: 226 KISSGE--FNCPPWLSL--GAMKLITRILDPNPMTRVTPQEVFEDEWFKK 271
>At1g01140 [T] KOG0583 Serine/threonine protein kinase
Length = 447
Score = 103 bits (258), Expect = 4e-22
Identities = 91/343 (26%), Positives = 155/343 (44%), Gaps = 64/343 (18%)
Query: 143 RIVGSGTFGHVLVAEKVDHNMKRQVAKKTVS---YAVKVINTAKT-------RMVKEATI 192
R +G G+F V + AK TV+ A+K+++ K ++ +E +
Sbjct: 23 RTLGEGSFAKV------------KYAKNTVTGDQAAIKILDREKVFRHKMVEQLKREIST 70
Query: 193 LEKLNHPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQI 252
++ + HPN++ I + +YI +L++GG+LF +A+ L E E+ Q+
Sbjct: 71 MKLIKHPNVVEIIEVMASKT-KIYIVLELVNGGELFDKIAQQGRL---KEDEARRYFQQL 126
Query: 253 LLALKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKE--RMHTVVGT 310
+ A+ + HS G+ HRDLK +N++L + + ++DFG++ S+ +E +HT GT
Sbjct: 127 INAVDYCHSRGVYHRDLKPENLIL---DANGVLKVSDFGLS-AFSRQVREDGLLHTACGT 182
Query: 311 PEYCAPEVGFKADRNIYRSFSRTATLDPDNNGYD-SKCDIWSLGVITHIMLTGISPFYGD 369
P Y APEV + GYD + D+WS GVI +++ G PF +
Sbjct: 183 PNYVAPEV-------------------LSDKGYDGAAADVWSCGVILFVLMAGYLPF-DE 222
Query: 370 GSEASIIKNVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKHT 429
+ ++ K R K F+ W + AK +K+ L+ + R + E L W +K
Sbjct: 223 PNLMTLYK--RICKAEFSCPPW--FSQGAKRVIKRILEPNPITRISIAELLEDEWFKKG- 277
Query: 430 SQLERIYKKKVLQLSSDCIKIDENIDTFAVVKHKLPKSVKLSP 472
YK + I ID+ F+ K L K P
Sbjct: 278 ------YKPPSFDQDDEDITIDDVDAAFSNSKECLVTEKKEKP 314
>YPL203w [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 380
Score = 103 bits (257), Expect = 6e-22
Identities = 81/252 (32%), Positives = 129/252 (51%), Gaps = 49/252 (19%)
Query: 141 VPRIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVK-------EATIL 193
+ R +G+G+FG V + V HN + YA+KV+ + +K E +L
Sbjct: 72 IMRTLGTGSFGRVHLVRSV-HNGRY--------YAIKVLKKQQVVKMKQVEHTNDERRML 122
Query: 194 EKLNHPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLV-PISETESLIIIYQI 252
+ + HP +IR+ + DA N+++ D I GG+LFS L K P+++ + ++
Sbjct: 123 KLVEHPFLIRMWGTFQDAR-NIFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAA----EV 177
Query: 253 LLALKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPE 312
+LAL++LH++ I++RDLK +NILL + + + DFG AKE+ T T+ GTP+
Sbjct: 178 ILALEYLHAHNIIYRDLKPENILL---DRNGHIKITDFGFAKEVQTVT----WTLCGTPD 230
Query: 313 YCAPEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSE 372
Y APEV T P Y+ D WSLGV+ + ML G +PFY D +
Sbjct: 231 YIAPEV---------------ITTKP----YNKSVDWWSLGVLIYEMLAGYTPFY-DTTP 270
Query: 373 ASIIKNVRTGKL 384
+ + GK+
Sbjct: 271 MKTYEKILQGKV 282
>CE00847 [T] KOG0583 Serine/threonine protein kinase
Length = 622
Score = 103 bits (257), Expect = 6e-22
Identities = 78/293 (26%), Positives = 138/293 (46%), Gaps = 50/293 (17%)
Query: 140 IVPRIVGSGTFGHVLVAEKVDHNMKRQVAKKT-VSYAVKVINTAKTRMV-------KEAT 191
++ +G G FG V KR +T A+K++N + + + E
Sbjct: 25 VIKETIGKGAFGAV----------KRGTHIQTGYDVAIKILNRGRMKGLGTVNKTRNEID 74
Query: 192 ILEKLNHPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQ 251
L+KL HP+I R+ + + ++++ +L+SGG+LFSY+ + L PI E+ Q
Sbjct: 75 NLQKLTHPHITRLFR-VISTPSDIFLVMELVSGGELFSYITRKGAL-PIRESRRYF--QQ 130
Query: 252 ILLALKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTP 311
I+ + + H++ IVHRDLK +N+LL + + +ADFG++ ++ + + T G+P
Sbjct: 131 IISGVSYCHNHMIVHRDLKPENLLLDANK---NIKIADFGLSNYMTDG--DLLSTACGSP 185
Query: 312 EYCAPEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGS 371
Y APE+ S + P+ D+WS GVI + ML G PF D +
Sbjct: 186 NYAAPEL-----------ISNKLYVGPE-------VDLWSCGVILYAMLCGTLPF-DDQN 226
Query: 372 EASIIKNVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVW 424
++ +++G+ ++ A + LQV R DV+ ++ W
Sbjct: 227 VPTLFAKIKSGRYTVP----YSMEKQAADLISTMLQVDPVKRADVKRIVNHSW 275
>At3g17510 [T] KOG0583 Serine/threonine protein kinase
Length = 446
Score = 103 bits (257), Expect = 6e-22
Identities = 83/287 (28%), Positives = 142/287 (48%), Gaps = 57/287 (19%)
Query: 143 RIVGSGTFGHVLVAEKVDHNMKRQVAKKTVS---YAVKVINTAKT-------RMVKEATI 192
R +G G FG V + AK TVS +AVK+I+ ++ ++ +E
Sbjct: 24 RTLGEGNFGKV------------KFAKDTVSGHSFAVKIIDKSRIADLNFSLQIKREIRT 71
Query: 193 LEKLNHPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQI 252
L+ L HP+I+R+H+ + + +L++GG+LF + L +ET+ + Q+
Sbjct: 72 LKMLKHPHIVRLHEVLASKT-KINMVMELVTGGELFDRIVSNGKL---TETDGRKMFQQL 127
Query: 253 LLALKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKE--RMHTVVGT 310
+ + + HS G+ HRDLKL+N+LL + + + DFG++ L Q+ ++ +HT G+
Sbjct: 128 IDGISYCHSKGVFHRDLKLENVLL---DAKGHIKITDFGLS-ALPQHFRDDGLLHTTCGS 183
Query: 311 PEYCAPEVGFKADRNIYRSFSRTATLDPDNNGYD-SKCDIWSLGVITHIMLTGISPFYGD 369
P Y APEV N GYD + DIWS GVI +++LTG PF D
Sbjct: 184 PNYVAPEV-------------------LANRGYDGAASDIWSCGVILYVILTGCLPF-DD 223
Query: 370 GSEASIIKNVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDV 416
+ A + + + G + +W ++ A++ +K+ L + R V
Sbjct: 224 RNLAVLYQKICKG--DPPIPRW--LSPGARTMIKRMLDPNPVTRITV 266
>At2g37840 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 257
Score = 103 bits (257), Expect = 6e-22
Identities = 79/249 (31%), Positives = 130/249 (51%), Gaps = 32/249 (12%)
Query: 140 IVPRIVGSGTFGHVLVAE-KVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKLNH 198
+V R +GSG+F V A +VD +VA K ++ ++ + ++ E IL ++NH
Sbjct: 13 LVGRQIGSGSFSVVWEARHRVDGT---EVAIKEIAMD-RLNKKLQESLMSEIFILRRINH 68
Query: 199 PNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKF 258
PNIIR+ + + G V++ + GGDL Y+ + +VP E + + Q+ L+
Sbjct: 69 PNIIRLIDM-IKSPGKVHLVLEYCKGGDLSVYVQRHG-IVP--EATAKHFMQQLAAGLQV 124
Query: 259 LHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEV 318
L N I+HRDLK N+LL T E + +ADFG A+ L + T+ G+P Y APE+
Sbjct: 125 LRDNNIIHRDLKPQNLLLSTNENDADLKIADFGFARSL--QPRGLAETLCGSPLYMAPEI 182
Query: 319 GFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKN 378
YD+K D+WS+G I ++TG +PF G+ S+ +++N
Sbjct: 183 -------------------MQLQKYDAKADLWSVGAILFQLVTGRTPFTGN-SQIQLLQN 222
Query: 379 -VRTGKLNF 386
+R+ +L+F
Sbjct: 223 IIRSTELHF 231
>7297542 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 353
Score = 103 bits (257), Expect = 6e-22
Identities = 90/346 (26%), Positives = 158/346 (45%), Gaps = 71/346 (20%)
Query: 119 SETMSQFMTGLRIKSEWDRWKIVP------------RIVGSGTFGHVLVAEKVDHNMKRQ 166
+ET+ +F+ + + E D+W+ P + +G+G+FG V++ V H +
Sbjct: 15 AETVKEFLEQAKEEFE-DKWRRNPTNTAALDDFERIKTLGTGSFGRVMI---VQHKPTKD 70
Query: 167 VAKKTVSYAVKVINTAKTRMVK-------EATILEKLNHPNIIRIHQSCVDALGNVYIFQ 219
YA+K+++ K +K E IL+ + P ++ + D N+Y+
Sbjct: 71 Y------YAMKILDKQKVVKLKQVEHTLNEKRILQAIQFPFLVSLRYHFKDN-SNLYMVL 123
Query: 220 DLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHSNGIVHRDLKLDNILLHTP 279
+ + GG++FS+L K + SE S QI+LA ++LH +++RDLK +N+L+ +
Sbjct: 124 EYVPGGEMFSHLRK---VGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQ 180
Query: 280 EPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKADRNIYRSFSRTATLDPD 339
+ + DFG AK + K R T+ GTPEY APE+
Sbjct: 181 ---GYLKVTDFGFAKRV----KGRTWTLCGTPEYLAPEIIL------------------- 214
Query: 340 NNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVRTGKLNFTARQWIAITDSAK 399
+ GY+ D W+LGV+ + M G PF+ D I + + +GK+ F + K
Sbjct: 215 SKGYNKAVDWWALGVLVYEMAAGYPPFFAD-QPIQIYEKIVSGKVRFPSH----FGSDLK 269
Query: 400 SFVKKCLQVSTFNR-----CDVEEALHQVWVEKHTSQLERIYKKKV 440
++ LQV R V + +Q W ++ I++KK+
Sbjct: 270 DLLRNLLQVDLTKRYGNLKAGVNDIKNQKWFA--STDWIAIFQKKI 313
>HsM4505103 [R] KOG0586 Serine/threonine protein kinase
Length = 713
Score = 103 bits (256), Expect = 8e-22
Identities = 89/344 (25%), Positives = 159/344 (45%), Gaps = 59/344 (17%)
Query: 143 RIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKLNHPNII 202
+ +G G F V +A + R+VA K + ++ T+ ++ +E I++ LNHPNI+
Sbjct: 60 KTIGKGNFAKVKLARHILTG--REVAIKIID-KTQLNPTSLQKLFREVRIMKILNHPNIV 116
Query: 203 RIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHSN 262
++ + ++ +Y+ + SGG +F YL + E E+ QI+ A+++ H
Sbjct: 117 KLFE-VIETQKTLYLIMEYASGGKVFDYLVAHGRM---KEKEARSKFRQIVSAVQYCHQK 172
Query: 263 GIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKA 322
IVHRDLK +N+LL + + +ADFG + E + K + T G+P Y APE+ F+
Sbjct: 173 RIVHRDLKAENLLL---DADMNIKIADFGFSNEFTVGGK--LDTFCGSPPYAAPEL-FQG 226
Query: 323 DRNIYRSFSRTATLDPDNNGYDS-KCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVRT 381
+ YD + D+WSLGVI + +++G PF G +K +R
Sbjct: 227 KK------------------YDGPEVDVWSLGVILYTLVSGSLPFDGQN-----LKELRE 263
Query: 382 GKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWV---------------E 426
L R ++ ++ +K+ L ++ R +E+ + W+ E
Sbjct: 264 RVLRGKYRIPFYMSTDCENLLKRFLVLNPIKRGTLEQIMKDRWINAGHEEDELKPFVEPE 323
Query: 427 KHTSQLERI-------YKKKVLQLSSDCIKIDENIDTFAVVKHK 463
S +RI Y ++ +Q S +K DE T+ ++ K
Sbjct: 324 LDISDQKRIDIMVGMGYSQEEIQESLSKMKYDEITATYLLLGRK 367
>Hs5453964 [T] KOG0583 Serine/threonine protein kinase
Length = 550
Score = 103 bits (256), Expect = 8e-22
Identities = 84/290 (28%), Positives = 136/290 (45%), Gaps = 48/290 (16%)
Query: 145 VGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMV-------KEATILEKLN 197
+G GTFG V V K ++ V AVK++N K R + +E L+
Sbjct: 24 LGVGTFGKVKVG-------KHELTGHKV--AVKILNRQKIRSLDVVGKIRREIQNLKLFR 74
Query: 198 HPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALK 257
HP+II+++Q + ++++ + +SGG+LF Y+ K L E ES + QIL +
Sbjct: 75 HPHIIKLYQ-VISTPSDIFMVMEYVSGGELFDYICKNGRL---DEKESRRLFQQILSGVD 130
Query: 258 FLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPE 317
+ H + +VHRDLK +N+LL + +ADFG++ +S E + T G+P Y APE
Sbjct: 131 YCHRHMVVHRDLKPENVLL---DAHMNAKIADFGLSNMMSDG--EFLRTSCGSPNYAAPE 185
Query: 318 VGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIK 377
V +Y + DIWS GVI + +L G PF D ++ K
Sbjct: 186 V---ISGRLYAG---------------PEVDIWSSGVILYALLCGTLPF-DDDHVPTLFK 226
Query: 378 NVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEK 427
+ G + +T + + S S +K LQV R +++ W ++
Sbjct: 227 KICDG-IFYTPQY---LNPSVISLLKHMLQVDPMKRASIKDIREHEWFKQ 272
>Hs4506055 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 351
Score = 103 bits (256), Expect = 8e-22
Identities = 84/311 (27%), Positives = 148/311 (47%), Gaps = 60/311 (19%)
Query: 143 RIVGSGTFGHVLVAEKVDHNMKRQVAKKTVS-YAVKVINTAKTRMVK-------EATILE 194
+ +G+G+FG V++ + K+T + YA+K+++ K +K E IL+
Sbjct: 48 KTLGTGSFGRVMLVKH----------KETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQ 97
Query: 195 KLNHPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILL 254
+N P ++++ S D N+Y+ + + GG++FS+L + + SE + QI+L
Sbjct: 98 AVNFPFLVKLEFSFKDN-SNLYMVMEYVPGGEMFSHLRR---IGRFSEPHARFYAAQIVL 153
Query: 255 ALKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYC 314
++LHS +++RDLK +N+L+ + + + DFG AK + K R T+ GTPEY
Sbjct: 154 TFEYLHSLDLIYRDLKPENLLI---DQQGYIQVTDFGFAKRV----KGRTWTLCGTPEYL 206
Query: 315 APEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEAS 374
APE+ + GY+ D W+LGV+ + M G PF+ D
Sbjct: 207 APEIIL-------------------SKGYNKAVDWWALGVLIYEMAAGYPPFFAD-QPIQ 246
Query: 375 IIKNVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRC-----DVEEALHQVWVEKHT 429
I + + +GK+ F + + K ++ LQV R V + + W T
Sbjct: 247 IYEKIVSGKVRFPSH----FSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFA--T 300
Query: 430 SQLERIYKKKV 440
+ IY++KV
Sbjct: 301 TDWIAIYQRKV 311
>Hs16418343 [T] KOG0583 Serine/threonine protein kinase
Length = 268
Score = 103 bits (256), Expect = 8e-22
Identities = 75/285 (26%), Positives = 129/285 (44%), Gaps = 35/285 (12%)
Query: 143 RIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKLNHPNII 202
+ +G GT+ V A H +R+VA K + + + +E I+ L+H NII
Sbjct: 14 KTIGEGTYSKVKEAFSKKH--QRKVAIKVIDKMGGPEEFIQRFLPRELQIVRTLDHKNII 71
Query: 203 RIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHSN 262
++++ A G + + +L GGD+F + G P+ E+ + + Q++ A+++ H
Sbjct: 72 QVYEMLESADGKICLVMELAEGGDVFDCVLNGG---PLPESRAKALFRQMVEAIRYCHGC 128
Query: 263 GIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEV--GF 320
G+ HRDLK +N LL + L DFG AK L ++ +E T G+ Y APEV G
Sbjct: 129 GVAHRDLKCENALLQG----FNLKLTDFGFAKVLPKSHRELSQTFCGSTAYAAPEVLQGI 184
Query: 321 KADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVR 380
D K D+WS+GV+ ++ML PF + I K +
Sbjct: 185 PHD--------------------SKKGDVWSMGVVLYVMLCASLPF----DDTDIPKMLW 220
Query: 381 TGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWV 425
+ + ++I+ + +K+ L+ R +EE W+
Sbjct: 221 QQQKGVSFPTHLSISADCQDLLKRLLEPDMILRPSIEEVSWHPWL 265
>At3g08730 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 465
Score = 103 bits (256), Expect = 8e-22
Identities = 82/239 (34%), Positives = 113/239 (46%), Gaps = 52/239 (21%)
Query: 141 VPRIVGSGTFGHVLVAEKVDHNMKRQVAKKTVS--YAVKVINTAKTR-------MVKEAT 191
V ++VG G FG V QV KK S YA+KV+ M E
Sbjct: 136 VMKVVGKGAFGKVY-----------QVRKKETSEIYAMKVMRKDHIMEKNHAEYMKAERD 184
Query: 192 ILEKLNHPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIY- 250
IL K++HP I+++ S +Y+ D I+GG LF L E L +Y
Sbjct: 185 ILTKIDHPFIVQLKYS-FQTKYRLYLVLDFINGGHLFFQLYHQGLF-----REDLARVYT 238
Query: 251 -QILLALKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVG 309
+I+ A+ LH GI+HRDLK +NIL+ T V+L DFG+AKE +NT R +++ G
Sbjct: 239 AEIVSAVSHLHEKGIMHRDLKPENILMDTD---GHVMLTDFGLAKEFEENT--RSNSMCG 293
Query: 310 TPEYCAPEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYG 368
T EY APE+ G+D D WS+G++ + MLTG PF G
Sbjct: 294 TTEYMAPEI-------------------VRGKGHDKAADWWSVGILLYEMLTGKPPFLG 333
>7302464 [R] KOG0586 Serine/threonine protein kinase
Length = 739
Score = 103 bits (256), Expect = 8e-22
Identities = 75/290 (25%), Positives = 147/290 (49%), Gaps = 38/290 (13%)
Query: 137 RWKIVPRIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKL 196
++K++ + +G G F V +A+ + ++VA K + ++ + ++ +E I++ L
Sbjct: 150 KYKLI-KTIGKGNFAKVKLAKHLPTG--KEVAIKIID-KTQLNPGSLQKLFREVRIMKML 205
Query: 197 NHPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLAL 256
+HPNI+++ Q ++ +Y+ + SGG++F YL + E E+ + QI+ A+
Sbjct: 206 DHPNIVKLFQ-VIETEKTLYLIMEYASGGEVFDYLVLHGRM---KEKEARVKFRQIVSAV 261
Query: 257 KFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAP 316
++ H I+HRDLK +N+LL + + +ADFG + E + +K + T G+P Y AP
Sbjct: 262 QYCHQKRIIHRDLKAENLLLDSE---LNIKIADFGFSNEFTPGSK--LDTFCGSPPYAAP 316
Query: 317 EVGFKADRNIYRSFSRTATLDPDNNGYDS-KCDIWSLGVITHIMLTGISPFYGDGSEASI 375
E+ F+ + YD + D+WSLGVI + +++G PF G S
Sbjct: 317 EL-FQGKK------------------YDGPEVDVWSLGVILYTLVSGSLPFDG-----ST 352
Query: 376 IKNVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWV 425
++ +R L R ++ ++ ++K L ++ R +E + W+
Sbjct: 353 LRELRERVLRGKYRIPFYMSTDCENLLRKFLVLNPAKRASLETIMGDKWM 402
>At5g12180 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 528
Score = 102 bits (255), Expect = 1e-21
Identities = 82/288 (28%), Positives = 137/288 (47%), Gaps = 38/288 (13%)
Query: 145 VGSGTFG--HVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVK-EATILEKLN-HPN 200
+G G FG H+ + H Q A KT++ K++N V+ E I+ L PN
Sbjct: 79 LGRGQFGVTHLCTQKATGH----QFACKTIAKR-KLVNKEDIEDVRREVQIMHHLTGQPN 133
Query: 201 IIRIHQSCVDALGNVYIFQDLISGGDLFS-YLAKGDCLVPISETESLIIIYQILLALKFL 259
I+ + + D +V++ +L +GG+LF +AKG SE + ++ I+ +
Sbjct: 134 IVELKGAYEDK-HSVHLVMELCAGGELFDRIIAKGH----YSERAAASLLRTIVQIVHTC 188
Query: 260 HSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVG 319
HS G++HRDLK +N LL + + + DFG++ + E +VG+ Y APEV
Sbjct: 189 HSMGVIHRDLKPENFLLLNKDENSPLKATDFGLS--VFYKPGEVFKDIVGSAYYIAPEV- 245
Query: 320 FKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNV 379
Y + DIWS+GV+ +I+L G+ PF+ + SE I +
Sbjct: 246 -------------------LKRKYGPEADIWSIGVMLYILLCGVPPFWAE-SENGIFNAI 285
Query: 380 RTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEK 427
G ++F++ W +I+ AK VKK L R + L+ W+++
Sbjct: 286 LRGHVDFSSDPWPSISPQAKDLVKKMLNSDPKQRLTAAQVLNHPWIKE 333
>At3g08720 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 471
Score = 102 bits (255), Expect = 1e-21
Identities = 82/239 (34%), Positives = 113/239 (46%), Gaps = 52/239 (21%)
Query: 141 VPRIVGSGTFGHVLVAEKVDHNMKRQVAKKTVS--YAVKVINTAKT-------RMVKEAT 191
V ++VG G FG V QV KK S YA+KV+ K M E
Sbjct: 142 VLKVVGQGAFGKVY-----------QVRKKDTSEIYAMKVMRKDKIVEKNHAEYMKAERD 190
Query: 192 ILEKLNHPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIY- 250
IL K++HP I+++ S +Y+ D I+GG LF L E L +Y
Sbjct: 191 ILTKIDHPFIVQLKYS-FQTKYRLYLVLDFINGGHLFFQLYHQGLF-----REDLARVYT 244
Query: 251 -QILLALKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVG 309
+I+ A+ LH GI+HRDLK +NIL+ V+L DFG+AKE +NT R +++ G
Sbjct: 245 AEIVSAVSHLHEKGIMHRDLKPENILMDVD---GHVMLTDFGLAKEFEENT--RSNSMCG 299
Query: 310 TPEYCAPEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYG 368
T EY APE+ G+D D WS+G++ + MLTG PF G
Sbjct: 300 TTEYMAPEI-------------------VRGKGHDKAADWWSVGILLYEMLTGKPPFLG 339
>At3g01090 [T] KOG0583 Serine/threonine protein kinase
Length = 512
Score = 102 bits (255), Expect = 1e-21
Identities = 82/319 (25%), Positives = 143/319 (44%), Gaps = 51/319 (15%)
Query: 143 RIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMV-------KEATILEK 195
R +G G+FG V +AE K A+K++N K + + +E IL
Sbjct: 23 RTLGIGSFGRVKIAEHALTGHK---------VAIKILNRRKIKNMEMEEKVRREIKILRL 73
Query: 196 LNHPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLA 255
HP+IIR+++ ++ ++Y+ + ++ G+LF Y+ + L E E+ QI+
Sbjct: 74 FMHPHIIRLYE-VIETPTDIYLVMEYVNSGELFDYIVEKGRL---QEDEARNFFQQIISG 129
Query: 256 LKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCA 315
+++ H N +VHRDLK +N+LL + V +ADFG++ + + T G+P Y A
Sbjct: 130 VEYCHRNMVVHRDLKPENLLLDSK---CNVKIADFGLSNIMRDG--HFLKTSCGSPNYAA 184
Query: 316 PEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASI 375
PEV +Y + D+WS GVI + +L G PF D + ++
Sbjct: 185 PEV---ISGKLYAG---------------PEVDVWSCGVILYALLCGTLPF-DDENIPNL 225
Query: 376 IKNVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKHTSQLERI 435
K ++ G + ++ A+ + + L V R + E W + H + +
Sbjct: 226 FKKIKGGIYTLPSH----LSPGARDLIPRMLVVDPMKRVTIPEIRQHPWFQAHLPRYLAV 281
Query: 436 YKKKVLQLSSDCIKIDENI 454
+Q + KIDE I
Sbjct: 282 PPPDTVQQAK---KIDEEI 297
>CE26793_1 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 795
Score = 102 bits (254), Expect = 1e-21
Identities = 73/237 (30%), Positives = 119/237 (49%), Gaps = 30/237 (12%)
Query: 132 KSEWDRWKIVPRIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEAT 191
K E R++I ++ GSGT+G V +A DH R+VA K + + R+ +E
Sbjct: 69 KKEKHRFEITKKL-GSGTYGKVSLA--YDHKFDREVAVKLIKKSAIESKADLVRIRREIR 125
Query: 192 ILEKLNHPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQ 251
I+ LNHPNII+I++ + + + + SGG+L+ Y+++ L E E+ I Q
Sbjct: 126 IMSALNHPNIIQIYE-VFENKDKIILVMEYSSGGELYDYVSRCGSL---PEAEARRIFRQ 181
Query: 252 ILLALKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTP 311
I A+ + H + + HRDLKL+NILL + +ADFG++ + K + T G+P
Sbjct: 182 ITSAVLYCHKHRVAHRDLKLENILL---DQNNNAKIADFGLSNYFAD--KNLLTTFCGSP 236
Query: 312 EYCAPEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYG 368
Y +PE+ + T P+ D WSLG++ + ++ G PF G
Sbjct: 237 LYASPEI-----------INGTPYKGPE-------VDCWSLGILLYTLVYGSMPFDG 275
>SPBC12D12.04c [T] KOG0694 Serine/threonine protein kinase
Length = 1016
Score = 102 bits (253), Expect = 2e-21
Identities = 70/232 (30%), Positives = 106/232 (45%), Gaps = 33/232 (14%)
Query: 144 IVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATIL-EKLNHPNII 202
++G G FG V++AE + + ++ T+ K ++ + HP ++
Sbjct: 688 VLGKGNFGKVMLAELKSEKQLYAIKVLKKEFILENDEVESTKSEKRVFLVANRERHPFLV 747
Query: 203 RIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHSN 262
+H SC +Y D +SGGDL ++ + S + ++ LALK+ H N
Sbjct: 748 NLH-SCFQTETRIYFVMDFVSGGDLMLHIQQEQ----FSRRRAQFYAAEVCLALKYFHDN 802
Query: 263 GIVHRDLKLDNILLHTPEPCTKVVLADFGIAKE--LSQNTKERMHTVVGTPEYCAPEVGF 320
GI++RDLKLDNILL P V +AD+G+ KE NT T GTPE+ APE+
Sbjct: 803 GIIYRDLKLDNILL---SPDGHVKVADYGLCKEDMWHDNTTA---TFCGTPEFMAPEILL 856
Query: 321 KADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSE 372
+ Y D W+ GV+ + ML G SPF G+ E
Sbjct: 857 EQQ-------------------YTRSVDWWAFGVLIYQMLLGQSPFRGEDEE 889
>Hs9845489 [R] KOG0586 Serine/threonine protein kinase
Length = 691
Score = 102 bits (253), Expect = 2e-21
Identities = 76/284 (26%), Positives = 141/284 (48%), Gaps = 37/284 (13%)
Query: 143 RIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKLNHPNII 202
+ +G G F V +A + ++VA K + ++ +++ ++ +E I++ LNHPNI+
Sbjct: 24 KTIGKGNFAKVKLARHILTG--KEVAVKIID-KTQLNSSSLQKLFREVRIMKVLNHPNIV 80
Query: 203 RIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHSN 262
++ + ++ +Y+ + SGG++F YL + E E+ QI+ A+++ H
Sbjct: 81 KLFE-VIETEKTLYLVMEYASGGEVFDYLVAHGRM---KEKEARAKFRQIVSAVQYCHQK 136
Query: 263 GIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKA 322
IVHRDLK +N+LL + + +ADFG + E + K + T G+P Y APE+ F+
Sbjct: 137 FIVHRDLKAENLLL---DADMNIKIADFGFSNEFTFGNK--LDTFCGSPPYAAPEL-FQG 190
Query: 323 DRNIYRSFSRTATLDPDNNGYDS-KCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVRT 381
+ YD + D+WSLGVI + +++G PF G +K +R
Sbjct: 191 KK------------------YDGPEVDVWSLGVILYTLVSGSLPFDGQN-----LKELRE 227
Query: 382 GKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWV 425
L R ++ ++ +KK L ++ R +E+ + W+
Sbjct: 228 RVLRGKYRIPFYMSTDCENLLKKFLILNPSKRGTLEQIMKDRWM 271
>Hs9845487 [R] KOG0586 Serine/threonine protein kinase
Length = 745
Score = 102 bits (253), Expect = 2e-21
Identities = 76/284 (26%), Positives = 141/284 (48%), Gaps = 37/284 (13%)
Query: 143 RIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKLNHPNII 202
+ +G G F V +A + ++VA K + ++ +++ ++ +E I++ LNHPNI+
Sbjct: 24 KTIGKGNFAKVKLARHILTG--KEVAVKIID-KTQLNSSSLQKLFREVRIMKVLNHPNIV 80
Query: 203 RIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHSN 262
++ + ++ +Y+ + SGG++F YL + E E+ QI+ A+++ H
Sbjct: 81 KLFE-VIETEKTLYLVMEYASGGEVFDYLVAHGRM---KEKEARAKFRQIVSAVQYCHQK 136
Query: 263 GIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKA 322
IVHRDLK +N+LL + + +ADFG + E + K + T G+P Y APE+ F+
Sbjct: 137 FIVHRDLKAENLLL---DADMNIKIADFGFSNEFTFGNK--LDTFCGSPPYAAPEL-FQG 190
Query: 323 DRNIYRSFSRTATLDPDNNGYDS-KCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVRT 381
+ YD + D+WSLGVI + +++G PF G +K +R
Sbjct: 191 KK------------------YDGPEVDVWSLGVILYTLVSGSLPFDGQN-----LKELRE 227
Query: 382 GKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWV 425
L R ++ ++ +KK L ++ R +E+ + W+
Sbjct: 228 RVLRGKYRIPFYMSTDCENLLKKFLILNPSKRGTLEQIMKDRWM 271
>Hs22062450 [R] KOG0586 Serine/threonine protein kinase
Length = 787
Score = 102 bits (253), Expect = 2e-21
Identities = 76/284 (26%), Positives = 141/284 (48%), Gaps = 37/284 (13%)
Query: 143 RIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKLNHPNII 202
+ +G G F V +A + ++VA K + ++ +++ ++ +E I++ LNHPNI+
Sbjct: 57 KTIGKGNFAKVKLARHILTG--KEVAVKIID-KTQLNSSSLQKLFREVRIMKVLNHPNIV 113
Query: 203 RIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHSN 262
++ + ++ +Y+ + SGG++F YL + E E+ QI+ A+++ H
Sbjct: 114 KLFE-VIETEKTLYLVMEYASGGEVFDYLVAHGRM---KEKEARAKFRQIVSAVQYCHQK 169
Query: 263 GIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKA 322
IVHRDLK +N+LL + + +ADFG + E + K + T G+P Y APE+ F+
Sbjct: 170 FIVHRDLKAENLLL---DADMNIKIADFGFSNEFTFGNK--LDTFCGSPPYAAPEL-FQG 223
Query: 323 DRNIYRSFSRTATLDPDNNGYDS-KCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVRT 381
+ YD + D+WSLGVI + +++G PF G +K +R
Sbjct: 224 KK------------------YDGPEVDVWSLGVILYTLVSGSLPFDGQN-----LKELRE 260
Query: 382 GKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWV 425
L R ++ ++ +KK L ++ R +E+ + W+
Sbjct: 261 RVLRGKYRIPFYMSTDCENLLKKFLILNPSKRGTLEQIMKDRWM 304
>Hs20547806 [R] KOG0589 Serine/threonine protein kinase
Length = 489
Score = 102 bits (253), Expect = 2e-21
Identities = 107/380 (28%), Positives = 168/380 (44%), Gaps = 66/380 (17%)
Query: 140 IVPRIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKLNHP 199
+V R++G G+FG L+ + N + A K + NT +R KEA +L K+ HP
Sbjct: 5 MVLRMIGEGSFGRALLVQHESSN--QMFAMKEIRLPKSFSNTQNSR--KEAVLLAKMKHP 60
Query: 200 NIIRIHQSCVDALGNVYIFQDLISGGDLFSYLA--KGDCLVPISETESLIIIY--QILLA 255
NI+ +S +A G++YI + GGDL + KG L P E +I+ + Q+ L
Sbjct: 61 NIVAFKES-FEAEGHLYIVMEYCDGGDLMQKIKQQKGK-LFP----EDMILNWFTQMCLG 114
Query: 256 LKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCA 315
+ +H ++HRD+K NI L KV L DFG A+ LS N T VGTP Y
Sbjct: 115 VNHIHKKRVLHRDIKSKNIFLTQNG---KVKLGDFGSARLLS-NPMAFACTYVGTPYYVP 170
Query: 316 PEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASI 375
PE+ +N Y++K DIWSLG I + + T PF + + I
Sbjct: 171 PEIW-------------------ENLPYNNKSDIWSLGCILYELCTLKHPFQANSWKNLI 211
Query: 376 IKNVR----------TGKLNFTARQWIAITDSAK-------------SFVKKCLQVSTFN 412
+K + + +L F +Q S + V+KCL
Sbjct: 212 LKVCQGCISPLPSHYSYELQFLVKQMFKRNPSHRPSATTLLSRGIVARLVQKCLPPEIIM 271
Query: 413 RCDVEEALHQVWVEKHTSQLERIYKKKVLQLS-SDCIKIDENIDTFAVVK----HKLPKS 467
EE L ++ KH + ++ +++ + S +D I+EN+ A+ + K KS
Sbjct: 272 EYG-EEVLEEIKNSKHNTPRKKQEEEQDRKGSHTDLESINENLVESALRRVNREEKGNKS 330
Query: 468 VKLSPEKNPNKRLKLFSNNI 487
V L +PN + + N+
Sbjct: 331 VHLRKASSPNLHRRQWEKNV 350
>Hs14042947 [T] KOG0583 Serine/threonine protein kinase
Length = 367
Score = 102 bits (253), Expect = 2e-21
Identities = 82/287 (28%), Positives = 129/287 (44%), Gaps = 36/287 (12%)
Query: 145 VGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKLNHPNIIRI 204
+G G++ V A +K VA K + + + + +E IL LNH +II+
Sbjct: 18 LGEGSYAKVKSA--YSERLKFNVAIKIIDRKKAPADFLEKFLPREIEILAMLNHCSIIKT 75
Query: 205 HQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHSNGI 264
++ + G VYI +L GDL + L E E+ +Q+ LA+K+ H +
Sbjct: 76 YEIFETSHGKVYIVMELAVQGDLLELIKTRGAL---HEDEARKKFHQLSLAIKYCHDLDV 132
Query: 265 VHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERM---HTVVGTPEYCAPEV--G 319
VHRDLK DN+LL + + L+DF +K ++ RM T G+P Y APEV G
Sbjct: 133 VHRDLKCDNLLL---DKDFNIKLSDFSFSKRCLRDDSGRMALSKTFCGSPAYAAPEVLQG 189
Query: 320 FKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNV 379
+Y DIWSLGVI +IM+ G P Y D + +++
Sbjct: 190 IPYQPKVY--------------------DIWSLGVILYIMVCGSMP-YDDSNIKKMLRIQ 228
Query: 380 RTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVE 426
+ ++NF + +T K + LQ R ++E L W++
Sbjct: 229 KEHRVNFPRSK--HLTGECKDLIYHMLQPDVNRRLHIDEILSHCWMQ 273
>CE27166 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 270
Score = 102 bits (253), Expect = 2e-21
Identities = 75/244 (30%), Positives = 123/244 (49%), Gaps = 40/244 (16%)
Query: 189 EATILEKLNHPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLII 248
E +L +L HP I++++ S D+ ++Y+ + + GG++FSYL S + +
Sbjct: 10 EKRVLLQLKHPFIVKMYASEKDS-NHLYMIMEFVPGGEMFSYLRASRSF---SNSMARFY 65
Query: 249 IYQILLALKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVV 308
+I+ AL+++HS GIV+RDLK +N++L + +ADFG AKEL ++R +T+
Sbjct: 66 ASEIVCALEYIHSLGIVYRDLKPENLMLSKE---GHIKMADFGFAKEL----RDRTYTIC 118
Query: 309 GTPEYCAPEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYG 368
GTP+Y APE S +RT G++ D W+LG++ + M+ G PF G
Sbjct: 119 GTPDYLAPE-----------SLART--------GHNKGVDWWALGILIYEMMVGKPPFRG 159
Query: 369 DGSEASIIKNVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRC-----DVEEALHQV 423
+ + I + KL F + +AK VKK L+V R ++
Sbjct: 160 K-TTSEIYDAIIEHKLKFPR----SFNLAAKDLVKKLLEVDRTQRIGCMKNGTQDVKDHK 214
Query: 424 WVEK 427
W EK
Sbjct: 215 WFEK 218
>At5g04870 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 610
Score = 102 bits (253), Expect = 2e-21
Identities = 77/285 (27%), Positives = 137/285 (48%), Gaps = 30/285 (10%)
Query: 143 RIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKL-NHPNI 201
R +G G FG + V+ ++ A K+++ + + + +E I+ L HPN+
Sbjct: 154 RKLGQGQFGTTFLC--VEKTTGKEFACKSIAKRKLLTDEDVEDVRREIQIMHHLAGHPNV 211
Query: 202 IRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHS 261
I I + D + V++ + +GG+LF + + +E ++ + I+ ++ HS
Sbjct: 212 ISIKGAYEDVVA-VHLVMECCAGGELFDRIIQRG---HYTERKAAELTRTIVGVVEACHS 267
Query: 262 NGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFK 321
G++HRDLK +N L + + + DFG++ + + VVG+P Y APEV K
Sbjct: 268 LGVMHRDLKPENFLFVSKHEDSLLKTIDFGLSMFFKPD--DVFTDVVGSPYYVAPEVLRK 325
Query: 322 ADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVRT 381
Y + D+WS GVI +I+L+G+ PF+ + +E I + V
Sbjct: 326 R--------------------YGPEADVWSAGVIVYILLSGVPPFWAE-TEQGIFEQVLH 364
Query: 382 GKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVE 426
G L+F++ W +I++SAK V+K L R + L WV+
Sbjct: 365 GDLDFSSDPWPSISESAKDLVRKMLVRDPKKRLTAHQVLCHPWVQ 409
>At1g29230 [T] KOG0583 Serine/threonine protein kinase
Length = 520
Score = 102 bits (253), Expect = 2e-21
Identities = 75/287 (26%), Positives = 133/287 (46%), Gaps = 36/287 (12%)
Query: 143 RIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKLNHPNII 202
+++G GTF V +A+ + K VA K + + + + +E +IL ++ HP I+
Sbjct: 78 KLLGHGTFAKVYLAQNIKSGDK--VAIKVIDKEKIMKSGLVAHIKREISILRRVRHPYIV 135
Query: 203 RIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHSN 262
+ + + +Y + + GG+LF+ +AKG + E + Q++ ++ F H
Sbjct: 136 HLFE-VMATKSKIYFVMEYVGGGELFNTVAKGR----LPEETARRYFQQLISSVSFCHGR 190
Query: 263 GIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERM-HTVVGTPEYCAPEVGFK 321
G+ HRDLK +N+LL + ++DFG++ Q ++ + HT GTP Y APEV
Sbjct: 191 GVYHRDLKPENLLLDNK---GNLKVSDFGLSAVAEQLRQDGLCHTFCGTPAYIAPEV--- 244
Query: 322 ADRNIYRSFSRTATLDPDNNGYD-SKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVR 380
GYD +K D+WS GVI +++ G PFY D + + K +
Sbjct: 245 ----------------LTRKGYDAAKADVWSCGVILFVLMAGHIPFY-DKNIMVMYKKIY 287
Query: 381 TGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEK 427
G+ F +W + + + L + R + E + W +K
Sbjct: 288 KGE--FRCPRW--FSSDLVRLLTRLLDTNPDTRITIPEIMKNRWFKK 330
>7293666 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 576
Score = 102 bits (253), Expect = 2e-21
Identities = 72/224 (32%), Positives = 104/224 (46%), Gaps = 29/224 (12%)
Query: 143 RIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKLNHPNII 202
R G G F E +D A K VS + + + K + +E TI LNHPNI+
Sbjct: 29 RFFGKGGFAKCY--EIIDVETDDVFAGKIVSKKLMIKHNQKEKTAQEITIHRSLNHPNIV 86
Query: 203 RIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHSN 262
+ H D+ N+YI +L + + I+E E IYQI+ +K+LH N
Sbjct: 87 KFHNYFEDSQ-NIYIVLELCKKRSMMELHKRRKS---ITEFECRYYIYQIIQGVKYLHDN 142
Query: 263 GIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKA 322
I+HRDLKL N+ L+ V + DFG+A + + ER T+ GTP Y APE+ K
Sbjct: 143 RIIHRDLKLGNLFLN---DLLHVKIGDFGLATRI-EYEGERKKTLCGTPNYIAPEILTK- 197
Query: 323 DRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPF 366
G+ + DIWS+G + + +L G PF
Sbjct: 198 ------------------KGHSFEVDIWSIGCVMYTLLVGQPPF 223
>Hs21361101 [T] KOG0607 MAP kinase-interacting kinase and related
serine/threonine protein kinases
Length = 465
Score = 101 bits (252), Expect = 2e-21
Identities = 92/381 (24%), Positives = 155/381 (40%), Gaps = 94/381 (24%)
Query: 136 DRWKIVPRIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINT----AKTRMVKEA- 190
D +K+ ++G G + V A + + + YAVK+I +++R+ +E
Sbjct: 46 DMYKLTSELLGEGAYAKVQGAVSLQNGKE---------YAVKIIEKQAGHSRSRVFREVE 96
Query: 191 TILEKLNHPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIY 250
T+ + + NI+ + + D +F+ L GG + +++ K +E E+ ++
Sbjct: 97 TLYQCQGNKNILELIEFFEDDTRFYLVFEKL-QGGSILAHIQKQK---HFNEREASRVVR 152
Query: 251 QILLALKFLHSN-----------------------------------------GIVHRDL 269
+ AL FLH+ GI HRDL
Sbjct: 153 DVAAALDFLHTKDKVSLCHLGWSAMAPSGLTAAPTSLGSSDPPTSASQVAGTTGIAHRDL 212
Query: 270 KLDNILLHTPEPCTKVVLADFGIAKELSQN------TKERMHTVVGTPEYCAPEVGFKAD 323
K +NIL +PE + V + DF + + N T + T G+ EY APEV
Sbjct: 213 KPENILCESPEKVSPVKICDFDLGSGMKLNNSCTPITTPELTTPCGSAEYMAPEV----- 267
Query: 324 RNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYG--------DGSEA-- 373
F+ AT YD +CD+WSLGV+ +IML+G PF G D E
Sbjct: 268 ---VEVFTDQATF------YDKRCDLWSLGVVLYIMLSGYPPFVGHCGADCGWDRGEVCR 318
Query: 374 ----SIIKNVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKHT 429
+ ++++ GK F + W I+ AK + K L R + L WV+
Sbjct: 319 VCQNKLFESIQEGKYEFPDKDWAHISSEAKDLISKLLVRDAKQRLSAAQVLQHPWVQGQA 378
Query: 430 SQLERIYKKKVLQLSSDCIKI 450
+ + + +VLQ +S + +
Sbjct: 379 PE-KGLPTPQVLQRNSSTMDL 398
>CE28993 [G] KOG0599 Phosphorylase kinase gamma subunit
Length = 370
Score = 101 bits (252), Expect = 2e-21
Identities = 65/201 (32%), Positives = 103/201 (50%), Gaps = 22/201 (10%)
Query: 225 GDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHSNGIVHRDLKLDNILLHTPEPCTK 284
G+LF L + V +SE + ++ Q+ ++++H+ IVHRDLKL+NIL E +
Sbjct: 5 GELFDVL---NSTVTVSEKRARRLMKQLFDGVEYMHARDIVHRDLKLENILCIDEE---R 58
Query: 285 VVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKADRNIYRSFSRTATLDPDNNGYD 344
+V++DFG A + + K + + GTP Y APE R D + GY
Sbjct: 59 IVISDFGFATRIPRGKK--LRDLCGTPGYLAPET------------IRCQWYD-NAEGYS 103
Query: 345 SKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVRTGKLNFTARQWIAITDSAKSFVKK 404
+ D W+LGVI + +L G +PFY + +++ ++ GK F QW IT AK+ + +
Sbjct: 104 LEVDEWALGVIMYTLLAGCAPFY-HRKQLMMLRLIQQGKFEFRNEQWANITAEAKNLITQ 162
Query: 405 CLQVSTFNRCDVEEALHQVWV 425
LQV R +E L W+
Sbjct: 163 LLQVDATKRISSKECLAHEWM 183
>At5g35410 [T] KOG0583 Serine/threonine protein kinase
Length = 446
Score = 101 bits (252), Expect = 2e-21
Identities = 74/228 (32%), Positives = 112/228 (48%), Gaps = 32/228 (14%)
Query: 141 VPRIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKLNHPN 200
V R +G GTF V A D VA K ++ + + N ++ +E +I++ + HPN
Sbjct: 13 VGRTIGEGTFAKVKFARNTDTG--DNVAIKIMAKSTILKNRMVDQIKREISIMKIVRHPN 70
Query: 201 IIRIHQSCVDALGNVYIFQDLISGGDLFSYLA-KGDCLVPISETESLIIIYQILLALKFL 259
I+R+++ +YI + ++GG+LF + KG + E+ES Q++ A+
Sbjct: 71 IVRLYEVLASP-SKIYIVLEFVTGGELFDRIVHKGR----LEESESRKYFQQLVDAVAHC 125
Query: 260 HSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVG 319
H G+ HRDLK +N+LL T + ++DFG++ L Q E + T GTP Y APEV
Sbjct: 126 HCKGVYHRDLKPENLLLDTN---GNLKVSDFGLS-ALPQEGVELLRTTCGTPNYVAPEV- 180
Query: 320 FKADRNIYRSFSRTATLDPDNNGYD-SKCDIWSLGVITHIMLTGISPF 366
GYD S DIWS GVI ++L G PF
Sbjct: 181 ------------------LSGQGYDGSAADIWSCGVILFVILAGYLPF 210
>At4g24400 [T] KOG0583 Serine/threonine protein kinase
Length = 445
Score = 101 bits (252), Expect = 2e-21
Identities = 77/294 (26%), Positives = 139/294 (47%), Gaps = 35/294 (11%)
Query: 143 RIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKLNHPNII 202
R +G GTF V A+ + VA K V + + ++ +E +I++ + HP ++
Sbjct: 13 RTIGEGTFAKVKFAQNTETG--ESVAMKIVDRSTIIKRKMVDQIKREISIMKLVRHPCVV 70
Query: 203 RIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHSN 262
R+++ +YI + I+GG+LF + + L SE+E+ +Q++ + + HS
Sbjct: 71 RLYEVLASRT-KIYIILEYITGGELFDKIVRNGRL---SESEARKYFHQLIDGVDYCHSK 126
Query: 263 GIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKA 322
G+ HRDLK +N+LL + + ++DFG++ L + + T GTP Y APEV
Sbjct: 127 GVYHRDLKPENLLLDSQ---GNLKISDFGLS-ALPEQGVTILKTTCGTPNYVAPEV---- 178
Query: 323 DRNIYRSFSRTATLDPDNNGYD-SKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVRT 381
+ GY+ + DIWS GVI ++++ G PF D + + + +
Sbjct: 179 ---------------LSHKGYNGAVADIWSCGVILYVLMAGYLPF--DEMDLPTLYS-KI 220
Query: 382 GKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKHTSQLERI 435
K F+ + A+ AKS + + L + R + E W K + ++ I
Sbjct: 221 DKAEFSCPSYFAL--GAKSLINRILDPNPETRITIAEIRKDEWFLKDYTPVQLI 272
>SPCC4G3.08 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 436
Score = 101 bits (251), Expect = 3e-21
Identities = 95/335 (28%), Positives = 158/335 (46%), Gaps = 51/335 (15%)
Query: 144 IVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVK-EATILEKLNHPNII 202
++G G++G VL+ ++ N R A+K + A V+ K E ILE++ HP I
Sbjct: 96 VLGRGSYGKVLLVKQ--KNTGRLFAQKQLKKASIVLRAKGLEQTKNERQILEEVRHPFIC 153
Query: 203 RIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIY--QILLALKFLH 260
R++ + D +Y+ GG+LFS+LA+ L E ++ Y ++ LAL LH
Sbjct: 154 RLYYAFQDH-DRLYLILQYAPGGELFSHLAEQRML-----PEDVVAFYTAELTLALIHLH 207
Query: 261 SNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGF 320
GIV+RDLK +N LL ++L DFG++K +++N + + VGT EYCAPE+
Sbjct: 208 KLGIVYRDLKPENCLLDAE---GHILLTDFGLSK-VAENGAD-CRSFVGTEEYCAPEILL 262
Query: 321 KADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVR 380
+ YD D WS+G++ +LTG PF + + I++ +
Sbjct: 263 E-------------------QPYDHAVDWWSMGILIFDLLTGSPPFTAN-NHKRIMEKIT 302
Query: 381 TGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVE------EAL--HQVWVEKHTSQL 432
K N +T A+ + K L+ + R + +A+ H+++ ++L
Sbjct: 303 RAKPNIP----FYVTSDARDIINKFLKKNPKQRLGADGPEKGYDAIKKHRIYRRIDWNKL 358
Query: 433 ERIYKKKVLQLSSDCIKIDENIDTFAVVKHKLPKS 467
E K+ + CI E + F+V KLP S
Sbjct: 359 E---KRMLPPPIVPCITNPEAAENFSVEFTKLPLS 390
>CE16081 [T] KOG0583 Serine/threonine protein kinase
Length = 334
Score = 101 bits (251), Expect = 3e-21
Identities = 77/284 (27%), Positives = 138/284 (48%), Gaps = 41/284 (14%)
Query: 145 VGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKLNHPNIIRI 204
+G+G F V + V K +VA K + A K+ A+ + +E +E++NHPNI+++
Sbjct: 55 LGAGNFSKVKLG--VHQLTKEKVAVKIMDKA-KMDAKAQKLLSREIQAMEEMNHPNIVKL 111
Query: 205 HQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHSNGI 264
+ V+ L V++ + SGG+L++Y+ + L +E ++ + QI+ A+ +HS I
Sbjct: 112 FE-VVETLTRVHLVIEYASGGELYTYVHERGKL---TEGDAKPLFAQIVSAVSHMHSRNI 167
Query: 265 VHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKADR 324
VHRD+K +N++ +P V L DFG + + + ++ + T G+P Y APE
Sbjct: 168 VHRDIKAENVMFSSP---NTVKLVDFGFSCLVDR--EQMLRTFCGSPPYAAPE------- 215
Query: 325 NIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVRTGKL 384
L D + D+W+LGV+ ML G++PF + V K+
Sbjct: 216 -----------LFQDTSYAGELVDVWALGVLLFFMLIGVTPFKAE--------TVPDMKV 256
Query: 385 NFTARQWIA---ITDSAKSFVKKCLQVSTFNRCDVEEALHQVWV 425
TA ++ ++ A +K L+ T R D++ W+
Sbjct: 257 LITAGKYQIPDYVSLLATELIKSMLKTDTGQRADIDSVKKHFWM 300
>At3g57530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 560
Score = 101 bits (251), Expect = 3e-21
Identities = 79/305 (25%), Positives = 142/305 (45%), Gaps = 42/305 (13%)
Query: 127 TGLRIKSEWDRWKIVPRIVGSGTFGHVLVA---EKVDHNMKRQVAKKTVSYAVKVINTAK 183
TG I+S++ + R +G G FG + E D + + KK + AV + + +
Sbjct: 55 TGREIESKYT----LGRELGRGEFGVTYLCTDKETDDVFACKSILKKKLRTAVDIEDVRR 110
Query: 184 TRMVKEATILEKL-NHPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYL-AKGDCLVPIS 241
E I+ + HPN++ + ++ D V++ +L GG+LF + A+G +
Sbjct: 111 -----EVEIMRHMPEHPNVVTLKETYEDEHA-VHLVMELCEGGELFDRIVARGH----YT 160
Query: 242 ETESLIIIYQILLALKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTK 301
E + + I+ ++ H +G++HRDLK +N L + + DFG++
Sbjct: 161 ERAAAAVTKTIMEVVQVCHKHGVMHRDLKPENFLFGNKKETAPLKAIDFGLSVFFKPG-- 218
Query: 302 ERMHTVVGTPEYCAPEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLT 361
ER + +VG+P Y APEV RN Y + DIWS GVI +I+L
Sbjct: 219 ERFNEIVGSPYYMAPEV---LKRN-----------------YGPEVDIWSAGVILYILLC 258
Query: 362 GISPFYGDGSEASIIKNVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALH 421
G+ PF+ + +E + + + L+F W ++++AK ++K L R ++ L
Sbjct: 259 GVPPFWAE-TEQGVAQAIIRSVLDFRRDPWPKVSENAKDLIRKMLDPDQKRRLTAQQVLD 317
Query: 422 QVWVE 426
W++
Sbjct: 318 HPWLQ 322
>7302861 [T] KOG0696 Serine/threonine protein kinase
Length = 700
Score = 101 bits (251), Expect = 3e-21
Identities = 77/265 (29%), Positives = 121/265 (45%), Gaps = 35/265 (13%)
Query: 143 RIVGSGTFGHVLVAEK--VDHNMKRQVAKKTVSYAVKVINTAKTRM-VKEATILEKLNHP 199
+++G G+FG VL+AE+ D +V +K V +I T + + E IL P
Sbjct: 375 KVIGKGSFGKVLLAERRGTDELYAVKVLRKDV-----IIQTDDMELPMNEKKILALSGRP 429
Query: 200 NIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFL 259
+ SC + ++ + GGDL ++ + E+ ++ ++ +AL FL
Sbjct: 430 PFLVSMHSCFQTMDRLFFVMEYCKGGDLMYHMQQYG---RFKESVAIFYAVEVAIALFFL 486
Query: 260 HSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVG 319
H I++RDLKLDNILL + V L DFG++KE ++ T GTP Y APE+
Sbjct: 487 HERDIIYRDLKLDNILL---DGEGHVKLVDFGLSKE-GVTERQTTRTFCGTPNYMAPEI- 541
Query: 320 FKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNV 379
+ DP Y D WS GV+ + G +PF GD E ++ +N+
Sbjct: 542 --------------VSYDP----YSIAADWWSFGVLLFEFMAGQAPFEGD-DETTVFRNI 582
Query: 380 RTGKLNFTARQWIAITDSAKSFVKK 404
+ K F + D SF+ K
Sbjct: 583 KDKKAVFPKHFSVEAMDIITSFLTK 607
>YBR028c [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 525
Score = 100 bits (250), Expect = 4e-21
Identities = 84/314 (26%), Positives = 139/314 (43%), Gaps = 72/314 (22%)
Query: 143 RIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKT------------------ 184
R++G G +G VL+ + V N + A K + A +I+ T
Sbjct: 132 RVLGQGAYGKVLLVKDV--NTSKLYAMKQLRKAEILISQTATDSKREDEDKNDGNNNDND 189
Query: 185 --------RMVKEATILEKLNHPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDC 236
R E +IL ++ HPNI+++ S D +Y+ I GG+LF +L +
Sbjct: 190 DGLSKRLERTFAERSILSEIEHPNIVKLFYSFHDN-SKLYLLLQYIPGGELFYHLKEHGT 248
Query: 237 LVPISETESLIIIYQILLALKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKEL 296
L ET +I AL+FLH+ G+V+RDLK +N LL+ +VL DFG++K+
Sbjct: 249 L---DETTVSFYAAEISCALRFLHTKGVVYRDLKPENCLLNQR---GHLVLTDFGLSKKS 302
Query: 297 SQNTK---------ERMHTVVGTPEYCAPEVGFKADRNIYRSFSRTATLDPDNNGYDSKC 347
+ ++ +++++GTPEYCAPE+ Y C
Sbjct: 303 ANDSAVDEEDPENVNALYSIIGTPEYCAPEILL-------------------GKAYSQNC 343
Query: 348 DIWSLGVITHIMLTGISPFYGDGSEASIIK---NVRTGKLNFTARQWIAITDSAKSFVKK 404
D +SLG + + ML G P+ G + I K N + K+ F +++ K +
Sbjct: 344 DWYSLGCLLYDMLVGKPPYTGSNHKVIINKIQQNKQGPKIPF------YLSEGMKDILNA 397
Query: 405 CLQVSTFNRCDVEE 418
L+ T R +V++
Sbjct: 398 LLKKETAKRWNVDK 411
>7295426 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 490
Score = 100 bits (250), Expect = 4e-21
Identities = 85/269 (31%), Positives = 129/269 (47%), Gaps = 38/269 (14%)
Query: 143 RIVGSGTFGHVLVAEKV-DHNMKRQVAKKTVSYAVKVIN---TAKTRMVKEATILEKLNH 198
+++G G +G V K + + A K + A V N TA TR E ILE + H
Sbjct: 81 KVLGKGGYGKVFQVRKTAGRDANKYFAMKVLKKASIVTNQKDTAHTRA--ERNILEAVKH 138
Query: 199 PNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKF 258
P I+ + + G +Y+ + +SGG+LF +L + + E + + +I+LAL
Sbjct: 139 PFIVELVYA-FQTDGKLYLILEYLSGGELFMHLEREGIFL---EDTTCFYLSEIILALGH 194
Query: 259 LHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEV 318
LH GI++RDLK +NILL + V L DFG+ KE Q HT GT EY APE+
Sbjct: 195 LHKLGIIYRDLKPENILL---DAQGHVKLTDFGLCKEHIQEGIV-THTFCGTIEYMAPEI 250
Query: 319 GFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKN 378
+ RS G+ D WSLG + MLTG+ PF + + + I+
Sbjct: 251 -------LTRS------------GHGKAVDWWSLGALMFDMLTGVPPFTAENRKKT-IET 290
Query: 379 VRTGKLNFTARQWIAITDSAKSFVKKCLQ 407
+ KLN A +T A+ V++ ++
Sbjct: 291 ILKAKLNLPA----YLTPEARDLVRRLMK 315
>CE21615 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 378
Score = 100 bits (249), Expect = 5e-21
Identities = 79/287 (27%), Positives = 129/287 (44%), Gaps = 43/287 (14%)
Query: 145 VGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVI----NTAKTRMVKEATILEKLNHPN 200
+G G G V VA VA T AVK + K ++ E ++++ HPN
Sbjct: 114 IGVGASGTVFVAN---------VAGSTDVVAVKRMAFKTQPKKEMLLTEIKVMKQYRHPN 164
Query: 201 IIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLH 260
++ +S + ++++ D + GG+L + K + + E + ++ + L AL FLH
Sbjct: 165 LVNYIESYLVDADDLWVVMDYLEGGNLTDVVVKTE----LDEGQIAAVLQECLKALHFLH 220
Query: 261 SNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGF 320
+ IVHRD+K DN+LL +V L D G ++ +K TVVGTP + +PE+
Sbjct: 221 RHSIVHRDIKSDNVLLGMN---GEVKLTDMGFCAQIQPGSKR--DTVVGTPYWMSPEILN 275
Query: 321 KADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVR 380
K Y+ K DIWSLG++ M+ G P+ + +I +
Sbjct: 276 KKQ-------------------YNYKVDIWSLGIMALEMIDGEPPYLRETPLKAIYLIAQ 316
Query: 381 TGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEK 427
GK R ++ +F+ KCL V R D E L +++K
Sbjct: 317 NGKPEIKQRD--RLSSEFNNFLDKCLVVDPDQRADTTELLAHPFLKK 361
>At5g19360 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 523
Score = 100 bits (249), Expect = 5e-21
Identities = 79/286 (27%), Positives = 138/286 (47%), Gaps = 34/286 (11%)
Query: 145 VGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVK-EATILEKLN-HPNII 202
+G G FG + + + Q A KT++ K++N V+ E I+ L PNI+
Sbjct: 74 LGRGQFGVTHLCTQKATGL--QFACKTIAKR-KLVNKEDIEDVRREVQIMHHLTGQPNIV 130
Query: 203 RIHQSCVDALGNVYIFQDLISGGDLFS-YLAKGDCLVPISETESLIIIYQILLALKFLHS 261
+ + D +V++ +L +GG+LF +AKG SE + ++ I+ + HS
Sbjct: 131 ELKGAYEDK-HSVHLVMELCAGGELFDRIIAKGH----YSERAAASLLRTIVQIIHTCHS 185
Query: 262 NGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFK 321
G++HRDLK +N LL + + + + DFG++ + E +VG+ Y APEV
Sbjct: 186 MGVIHRDLKPENFLLLSKDENSPLKATDFGLS--VFYKPGEVFKDIVGSAYYIAPEV--- 240
Query: 322 ADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVRT 381
Y + DIWS+GV+ +I+L G+ PF+ + SE I + +
Sbjct: 241 -----------------LRRKYGPEADIWSIGVMLYILLCGVPPFWAE-SENGIFNAILS 282
Query: 382 GKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEK 427
G+++F++ W I+ AK V+K L R + L+ W+++
Sbjct: 283 GQVDFSSDPWPVISPQAKDLVRKMLNSDPKQRLTAAQVLNHPWIKE 328
>SPAC23C11.16 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 683
Score = 100 bits (248), Expect = 6e-21
Identities = 73/262 (27%), Positives = 120/262 (44%), Gaps = 31/262 (11%)
Query: 145 VGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKLNHPNIIRI 204
+G G F +V N A K ++ + K ++ E + + ++HPNI+
Sbjct: 47 IGEGGFARCF---RVKDNYGNIYAAKVIAKRSLQNDKTKLKLFGEIKVHQSMSHPNIVGF 103
Query: 205 HQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHSNGI 264
C + N+Y+ +L L L K L +E E ++ QIL ALK++H +
Sbjct: 104 ID-CFEDSTNIYLILELCEHKSLMELLRKRKQL---TEPEVRYLMMQILGALKYMHKKRV 159
Query: 265 VHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKADR 324
+HRDLKL NI+L + V + DFG+A L + +ER T+ GTP Y APE+ F +
Sbjct: 160 IHRDLKLGNIML---DESNNVKIGDFGLA-ALLMDDEERKMTICGTPNYIAPEILFNS-- 213
Query: 325 NIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVRTGKL 384
G+ + D+WS GV+ + +L G PF D +I + ++
Sbjct: 214 ---------------KEGHSFEVDLWSAGVVMYALLIGKPPFQ-DKEVKTIYRKIKANSY 257
Query: 385 NFTARQWIAITDSAKSFVKKCL 406
+F + + I+ AK + L
Sbjct: 258 SFPSN--VDISAEAKDLISSLL 277
>Hs4759044 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1388
Score = 100 bits (248), Expect = 6e-21
Identities = 83/295 (28%), Positives = 141/295 (47%), Gaps = 57/295 (19%)
Query: 85 VNEQVLSRDVPYLLSNQDVIQLPNGAKFKFSAVKSETMSQFMTGLRIKSE-WDRWKIVPR 143
+N VL D P L N+++ N + E + + + GL++K+E +D V +
Sbjct: 50 LNSLVLDLDFPALRKNKNIDNFLN---------RYEKIVKKIKGLQMKAEDYD----VVK 96
Query: 144 IVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVK---------EATILE 194
++G G FG V + V H ++V YA+K+++ K M+K E I+
Sbjct: 97 VIGRGAFGEV---QLVRHKASQKV------YAMKLLS--KFEMIKRSDSAFFWEERDIMA 145
Query: 195 KLNHPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILL 254
N P ++++ + D +Y+ + + GGDL + ++ D + E + +++L
Sbjct: 146 FANSPWVVQLFYAFQDDR-YLYMVMEYMPGGDLVNLMSNYD----VPEKWAKFYTAEVVL 200
Query: 255 ALKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYC 314
AL +HS G++HRD+K DN+LL + + LADFG ++ + T VGTP+Y
Sbjct: 201 ALDAIHSMGLIHRDVKPDNMLL---DKHGHLKLADFGTCMKMDETGMVHCDTAVGTPDYI 257
Query: 315 APEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGD 369
+PEV + Y +CD WS+GV + ML G +PFY D
Sbjct: 258 SPEV---------------LKSQGGDGFYGRECDWWSVGVFLYEMLVGDTPFYAD 297
>Hs20536595 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1388
Score = 100 bits (248), Expect = 6e-21
Identities = 83/295 (28%), Positives = 141/295 (47%), Gaps = 57/295 (19%)
Query: 85 VNEQVLSRDVPYLLSNQDVIQLPNGAKFKFSAVKSETMSQFMTGLRIKSE-WDRWKIVPR 143
+N VL D P L N+++ N + E + + + GL++K+E +D V +
Sbjct: 50 LNSLVLDLDFPALRKNKNIDNFLN---------RYEKIVKKIRGLQMKAEDYD----VVK 96
Query: 144 IVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVK---------EATILE 194
++G G FG V + V H ++V YA+K+++ K M+K E I+
Sbjct: 97 VIGRGAFGEV---QLVRHKASQKV------YAMKLLS--KFEMIKRSDSAFFWEERDIMA 145
Query: 195 KLNHPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILL 254
N P ++++ + D +Y+ + + GGDL + ++ D + E + +++L
Sbjct: 146 FANSPWVVQLFYAFQDDR-YLYMVMEYMPGGDLVNLMSNYD----VPEKWAKFYTAEVVL 200
Query: 255 ALKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYC 314
AL +HS G++HRD+K DN+LL + + LADFG ++ + T VGTP+Y
Sbjct: 201 ALDAIHSMGLIHRDVKPDNMLL---DKHGHLKLADFGTCMKMDETGMVHCDTAVGTPDYI 257
Query: 315 APEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGD 369
+PEV + Y +CD WS+GV + ML G +PFY D
Sbjct: 258 SPEV---------------LKSQGGDGFYGRECDWWSVGVFLYEMLVGDTPFYAD 297
>At3g61960 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 648
Score = 100 bits (248), Expect = 6e-21
Identities = 76/249 (30%), Positives = 121/249 (48%), Gaps = 37/249 (14%)
Query: 142 PRIVGSGTFGHVLVAEKVDHNMK---RQVAKKTVSYAVKVINTAKTRMVKEATILEKLNH 198
PRI GSG+F V +A+ ++ +++ KK +S V+ ++KE +IL ++H
Sbjct: 14 PRI-GSGSFAVVWLAKHRSSGLEVAVKEIDKKLLSPKVR------DNLLKEISILSTIDH 66
Query: 199 PNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKF 258
PNIIR +++ ++ +++ + SGGDL Y+ + + E + + Q+ L L+
Sbjct: 67 PNIIRFYEA-IETGDRIFLVLEYCSGGDLAGYINRHG---KVPEAVAKHFMRQLALGLQV 122
Query: 259 LHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERM-HTVVGTPEYCAPE 317
L +HRDLK N+LL + E + + DFG A+ L T E M T G+P Y APE
Sbjct: 123 LQEKHFIHRDLKPQNLLLSSKEVTPLLKIGDFGFARSL---TPESMAETFCGSPLYMAPE 179
Query: 318 VGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIK 377
+ N YD+K D+WS G I ++TG PF G+
Sbjct: 180 I-------------------IRNQKYDAKADLWSAGAILFQLVTGKPPFDGNNHIQLFHN 220
Query: 378 NVRTGKLNF 386
VR +L F
Sbjct: 221 IVRDTELKF 229
>At3g51850 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 503
Score = 100 bits (248), Expect = 6e-21
Identities = 77/296 (26%), Positives = 146/296 (49%), Gaps = 39/296 (13%)
Query: 136 DRWKIVPRIVGSGTFGHV-LVAEKVDHNMK--RQVAKKTVSYAVKVINTAKTRMVKEATI 192
DR+ ++ R +G G FG L E+ ++ + ++K+ + AV + + + E I
Sbjct: 52 DRY-LLDRELGRGEFGVTYLCIERSSRDLLACKSISKRKLRTAVDIEDVKR-----EVAI 105
Query: 193 LEKL-NHPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYL-AKGDCLVPISETESLIIIY 250
++ L +I+ + ++C D V++ +L GG+LF + A+G +E + +
Sbjct: 106 MKHLPKSSSIVTLKEACEDD-NAVHLVMELCEGGELFDRIVARGH----YTERAAAGVTK 160
Query: 251 QILLALKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGT 310
I+ ++ H +G++HRDLK +N L + + + DFG++ + E+ +VG+
Sbjct: 161 TIVEVVQLCHKHGVIHRDLKPENFLFANKKENSPLKAIDFGLS--IFFKPGEKFSEIVGS 218
Query: 311 PEYCAPEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDG 370
P Y APEV RN Y + DIWS GVI +I+L G+ PF+ +
Sbjct: 219 PYYMAPEV---LKRN-----------------YGPEIDIWSAGVILYILLCGVPPFWAE- 257
Query: 371 SEASIIKNVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVE 426
SE + + + G ++F W I+++AK+ V++ L+ R ++ L W++
Sbjct: 258 SEQGVAQAILRGVIDFKREPWPNISETAKNLVRQMLEPDPKRRLTAKQVLEHPWIQ 313
>At1g61950 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 547
Score = 100 bits (248), Expect = 6e-21
Identities = 75/287 (26%), Positives = 136/287 (47%), Gaps = 31/287 (10%)
Query: 143 RIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKLN-HPNI 201
R +G G FG + ++ + A K++ + + + +E I+ L+ PNI
Sbjct: 102 RELGRGQFGITYICTEISSG--KNFACKSILKRKLIRTKDREDVRREIQIMHYLSGQPNI 159
Query: 202 IRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHS 261
+ I + D +V++ +L GG+LF + K SE + II ++ ++ H
Sbjct: 160 VEIKGAYEDRQ-SVHLVMELCEGGELFDKITKRG---HYSEKAAAEIIRSVVKVVQICHF 215
Query: 262 NGIVHRDLKLDNILLHTPEPCTKVVLA-DFGIAKELSQNTKERMHTVVGTPEYCAPEVGF 320
G++HRDLK +N LL + + + ++ A DFG++ + + + +VG+ Y APEV
Sbjct: 216 MGVIHRDLKPENFLLSSKDEASSMLKATDFGVSVFIEEG--KVYEDIVGSAYYVAPEV-- 271
Query: 321 KADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVR 380
RN Y DIWS GVI +I+L G PF+ + ++ I + +
Sbjct: 272 -LKRN-----------------YGKAIDIWSAGVILYILLCGNPPFWAE-TDKGIFEEIL 312
Query: 381 TGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEK 427
G+++F + W +I++SAK V+ L+ R + L W+ +
Sbjct: 313 RGEIDFESEPWPSISESAKDLVRNMLKYDPKKRFTAAQVLEHPWIRE 359
>YLR248w [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 610
Score = 99.8 bits (247), Expect = 8e-21
Identities = 73/242 (30%), Positives = 113/242 (46%), Gaps = 59/242 (24%)
Query: 216 YIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHSNGIVHRDLKLDNIL 275
YI Q+L++GG++F + + L SE S +I Q+ LA+K +HS G+VHRD+K +N+L
Sbjct: 264 YIIQELLTGGEIFGEIVR---LTYFSEDLSRHVIKQLALAVKHMHSLGVVHRDIKPENLL 320
Query: 276 LH--------------TPEPCTK-----------------VVLADFGIAKEL-SQNTKER 303
+ +P TK V LADFG++K++ S+NTK
Sbjct: 321 FEPIEFTRSIKPKLRKSDDPQTKADEGIFTPGVGGGGIGIVKLADFGLSKQIFSKNTK-- 378
Query: 304 MHTVVGTPEYCAPEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGI 363
T GT Y APEV + Y K D+W +G + + ML G
Sbjct: 379 --TPCGTVGYTAPEV-------------------VKDEHYSMKVDMWGIGCVLYTMLCGF 417
Query: 364 SPFYGDGSEASIIKNVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQV 423
PFY D ++ + + G+ F W I+ AK+ V K L++ R D+++ L
Sbjct: 418 PPFY-DEKIDTLTEKISRGEYTFLKPWWDEISAGAKNAVAKLLELEPSKRYDIDQFLDDP 476
Query: 424 WV 425
W+
Sbjct: 477 WL 478
>YDR477w [T] KOG0583 Serine/threonine protein kinase
Length = 633
Score = 99.8 bits (247), Expect = 8e-21
Identities = 79/284 (27%), Positives = 136/284 (47%), Gaps = 35/284 (12%)
Query: 141 VPRIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKLNHPN 200
+ + +G G+FG V +A K VA K ++ V + + R+ +E + L L HP+
Sbjct: 57 IVKTLGEGSFGKVKLAYHTTTGQK--VALKIINKKVLAKSDMQGRIEREISYLRLLRHPH 114
Query: 201 IIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLH 260
II+++ + + + +G +LF Y+ + D +SE E+ QI+ A+++ H
Sbjct: 115 IIKLYDVIKSKDEIIMVIE--YAGNELFDYIVQRD---KMSEQEARRFFQQIISAVEYCH 169
Query: 261 SNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGF 320
+ IVHRDLK +N+LL + V +ADFG++ ++ + T G+P Y APEV
Sbjct: 170 RHKIVHRDLKPENLLL---DEHLNVKIADFGLSNIMTDG--NFLKTSCGSPNYAAPEV-- 222
Query: 321 KADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVR 380
+Y + D+WS GVI ++ML PF D S + KN+
Sbjct: 223 -ISGKLYAG---------------PEVDVWSCGVILYVMLCRRLPF-DDESIPVLFKNIS 265
Query: 381 TGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVW 424
G +T ++ ++ A +K+ L V+ NR + E + W
Sbjct: 266 NGV--YTLPKF--LSPGAAGLIKRMLIVNPLNRISIHEIMQDDW 305
>7293249 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1390
Score = 99.8 bits (247), Expect = 8e-21
Identities = 86/310 (27%), Positives = 143/310 (45%), Gaps = 33/310 (10%)
Query: 143 RIVGSGTFGHVLVAEKVDHNMKRQV-AKKTVSYAVKVINTAKTRMVKEATILEKLNHPNI 201
+++G+G FG V + V H QV A K +S + +E I+ N I
Sbjct: 91 KLIGAGAFGEV---QLVRHKSSSQVYAMKRLSKFEMMKRPDSAFFWEERHIMAHANSEWI 147
Query: 202 IRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHS 261
+++H + DA +Y+ D + GGD+ S + D I E ++ +++LAL +H+
Sbjct: 148 VQLHFAFQDAK-YLYMVMDFMPGGDIVSLMGDYD----IPEKWAIFYTMEVVLALDTIHN 202
Query: 262 NGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFK 321
G VHRD+K DN+LL + + LADFG + N + VGTP+Y +PEV
Sbjct: 203 MGFVHRDVKPDNMLL---DSYGHLKLADFGTCMRMGANGQVVSSNAVGTPDYISPEV--- 256
Query: 322 ADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVRT 381
++ +D N Y +CD WS+G+ + ML G +PFY D S +
Sbjct: 257 ---------LQSQGVD---NEYGRECDWWSVGIFLYEMLFGETPFYAD-SLVGTYGKIMD 303
Query: 382 GKLNFTARQWIAITDSAKSFVKKCL--QVSTFNRCDVEEALHQVWVEKHTSQLERIYKK- 438
K + + + I++ AK+ ++ L + R +E+ + T + I +
Sbjct: 304 HKNSLSFPPEVEISEQAKALIRAFLTDRTQRLGRYGIEDIKAHPFFRNDTWSFDNIRESV 363
Query: 439 --KVLQLSSD 446
V +LSSD
Sbjct: 364 PPVVPELSSD 373
>SPBC106.10 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 512
Score = 99.4 bits (246), Expect = 1e-20
Identities = 78/249 (31%), Positives = 123/249 (49%), Gaps = 46/249 (18%)
Query: 145 VGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVK-------EATILEKLN 197
+G+G+FG V + + +HN + YA+KV+ K +K E IL ++
Sbjct: 207 LGTGSFGRVHLVQS-NHNR--------LYYAIKVLEKKKIVDMKQIEHTCDERYILSRVQ 257
Query: 198 HPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALK 257
HP I + + DA N+++ D GG+LFS L K E + +++LAL
Sbjct: 258 HPFITILWGTFQDAK-NLFMVMDFAEGGELFSLLRKCH---RFPEKVAKFYAAEVILALD 313
Query: 258 FLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPE 317
+LH N IV+RDLK +N+LL + + + DFG AK +S + T+ GTP+Y APE
Sbjct: 314 YLHHNQIVYRDLKPENLLL---DRFGHLKIVDFGFAKRVSTS---NCCTLCGTPDYLAPE 367
Query: 318 VGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIK 377
+ +L P Y+ D WSLG++ ML G PFY + + + +
Sbjct: 368 I---------------ISLKP----YNKAADWWSLGILIFEMLAGYPPFYSE-NPMKLYE 407
Query: 378 NVRTGKLNF 386
N+ GK+N+
Sbjct: 408 NILEGKVNY 416
>Hs7661974 [T] KOG0583 Serine/threonine protein kinase
Length = 651
Score = 99.4 bits (246), Expect = 1e-20
Identities = 67/265 (25%), Positives = 127/265 (47%), Gaps = 31/265 (11%)
Query: 185 RMVKEATILEKLNHPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETE 244
R+ E L+ L H +I +++ ++ +++ + GG+LF Y+ D L SE E
Sbjct: 53 RIKTEIEALKNLRHQHICQLYH-VLETANKIFMVLEYCPGGELFDYIISQDRL---SEEE 108
Query: 245 SLIIIYQILLALKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERM 304
+ ++ QI+ A+ ++HS G HRDLK +N+L + K+ L DFG+ + N +
Sbjct: 109 TRVVFRQIVSAVAYVHSQGYAHRDLKPENLLF---DEYHKLKLIDFGLCAKPKGNKDYHL 165
Query: 305 HTVVGTPEYCAPEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGIS 364
T G+ Y APE L + S+ D+WS+G++ ++++ G
Sbjct: 166 QTCCGSLAYAAPE------------------LIQGKSYLGSEADVWSMGILLYVLMCGFL 207
Query: 365 PFYGDGSEASIIKNVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVW 424
PF D + ++ K + GK + +W ++ S+ +++ LQV R ++ L+ W
Sbjct: 208 PF-DDDNVMALYKKIMRGK--YDVPKW--LSPSSILLLQQMLQVDPKKRISMKNLLNHPW 262
Query: 425 V-EKHTSQLERIYKKKVLQLSSDCI 448
+ + + +E K + L DC+
Sbjct: 263 IMQDYNYPVEWQSKNPFIHLDDDCV 287
>Hs19923464 [T] KOG0577 Serine/threonine protein kinase
Length = 898
Score = 99.4 bits (246), Expect = 1e-20
Identities = 86/285 (30%), Positives = 123/285 (42%), Gaps = 37/285 (12%)
Query: 145 VGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKLNHPNIIRI 204
+G G+FG V A N VA K +SY+ K + ++KE L +L HPN I
Sbjct: 30 IGHGSFGAVYFATNAHTN--EVVAIKKMSYSGKQTHEKWQDILKEVKFLRQLKHPNTIE- 86
Query: 205 HQSCVDALGNVYIFQD--LISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHSN 262
++ C ++ + L S DL K P+ E E I + L L +LHS+
Sbjct: 87 YKGCYLKEHTAWLVMEYCLGSASDLLEVHKK-----PLQEVEIAAITHGALHGLAYLHSH 141
Query: 263 GIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKA 322
++HRD+K NILL P +V LADFG A S ++ VGTP + APEV
Sbjct: 142 ALIHRDIKAGNILLTEP---GQVKLADFGSASMASP-----ANSFVGTPYWMAPEV---- 189
Query: 323 DRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVRTG 382
L D YD K DIWSLG+ + P + + +++ +
Sbjct: 190 ------------ILAMDEGQYDGKVDIWSLGITCIELAERKPPLFNMNAMSALYHIAQND 237
Query: 383 KLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEK 427
+ +W TDS + FV CLQ R E L +V +
Sbjct: 238 SPTLQSNEW---TDSFRRFVDYCLQKIPQERPTSAELLRHDFVRR 279
>Hs16950619 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 1841
Score = 99.4 bits (246), Expect = 1e-20
Identities = 65/209 (31%), Positives = 107/209 (51%), Gaps = 25/209 (11%)
Query: 225 GDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHSNGIVHRDLKLDNILLHTPEPCTK 284
G LF + D ++E E + + QI ++++H GIVH DLK +NI+ + T+
Sbjct: 1471 GSLFERIIDED--FELTERECIKYMRQISEGVEYIHKQGIVHLDLKPENIMC-VNKTGTR 1527
Query: 285 VVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKADRNIYRSFSRTATLDPDNNGYD 344
+ L DFG+A+ L + + GTPE+ APEV ++ + GY
Sbjct: 1528 IKLIDFGLARRLENAGS--LKVLFGTPEFVAPEV-----------------INYEPIGYA 1568
Query: 345 SKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVRTGKLNFTARQWIAITDSAKSFVKK 404
+ D+WS+GVI +I+++G+SPF GD ++ + NV + +F + I+D AK F+
Sbjct: 1569 T--DMWSIGVICYILVSGLSPFMGD-NDNETLANVTSATWDFDDEAFDEISDDAKDFISN 1625
Query: 405 CLQVSTFNRCDVEEALHQVWVEKHTSQLE 433
L+ NR D + L W+ K T +E
Sbjct: 1626 LLKKDMKNRLDCTQCLQHPWLMKDTKNME 1654
>At3g29160 [T] KOG0583 Serine/threonine protein kinase
Length = 512
Score = 99.4 bits (246), Expect = 1e-20
Identities = 75/293 (25%), Positives = 132/293 (44%), Gaps = 48/293 (16%)
Query: 143 RIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMV-------KEATILEK 195
+ +G G+FG V +AE V K A+K++N K + + +E IL
Sbjct: 24 KTLGIGSFGKVKIAEHVVTGHK---------VAIKILNRRKIKNMEMEEKVRREIKILRL 74
Query: 196 LNHPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLA 255
HP+IIR ++ ++ ++Y+ + + G+LF Y+ + L E E+ QI+
Sbjct: 75 FMHPHIIRQYE-VIETTSDIYVVMEYVKSGELFDYIVEKGRL---QEDEARNFFQQIISG 130
Query: 256 LKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCA 315
+++ H N +VHRDLK +N+LL + + +ADFG++ + + T G+P Y A
Sbjct: 131 VEYCHRNMVVHRDLKPENLLL---DSRCNIKIADFGLSNVMRDG--HFLKTSCGSPNYAA 185
Query: 316 PEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASI 375
PEV +Y + D+WS GVI + +L G PF D + ++
Sbjct: 186 PEV---ISGKLYAG---------------PEVDVWSCGVILYALLCGTLPF-DDENIPNL 226
Query: 376 IKNVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKH 428
K ++ G + ++ A+ + + L V R + E W + H
Sbjct: 227 FKKIKGGIYTLPSH----LSSEARDLIPRMLIVDPVKRITIPEIRQHRWFQTH 275
>7301734 [T] KOG0694 Serine/threonine protein kinase
Length = 739
Score = 99.4 bits (246), Expect = 1e-20
Identities = 70/232 (30%), Positives = 111/232 (47%), Gaps = 32/232 (13%)
Query: 143 RIVGSGTFGHVLVAEK--VDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKLNHPN 200
+++G G+FG V++AEK D +V KK A+ + M ++ + NHP
Sbjct: 412 KVLGKGSFGKVMLAEKKGTDEIYAIKVLKKD---AIIQDDDVDCTMTEKRILALAANHPF 468
Query: 201 IIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLH 260
+ +H SC ++ + ++GGDL + K + + ++ LAL+FLH
Sbjct: 469 LTALH-SCFQTPDRLFFVMEYVNGGDLMFQIQKAR---RFEASRAAFYAAEVTLALQFLH 524
Query: 261 SNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGF 320
++G+++RDLKLDNILL C LADFG+ KE N T GTP+Y APE+
Sbjct: 525 THGVIYRDLKLDNILLDQEGHCK---LADFGMCKEGIMNGM-LTTTFCGTPDYIAPEILK 580
Query: 321 KADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSE 372
+ + Y + D W+LGV+ + M+ G PF D +
Sbjct: 581 EQE-------------------YGASVDWWALGVLMYEMMAGQPPFEADNED 613
>7300559 [T] KOG4279 Serine/threonine protein kinase
Length = 1310
Score = 99.4 bits (246), Expect = 1e-20
Identities = 86/290 (29%), Positives = 132/290 (44%), Gaps = 42/290 (14%)
Query: 144 IVGSGTFGHVLVAEKVDHNMKRQVAKKT-VSYAVKVINTAKTRMVK----EATILEKLNH 198
++G GT+G V A K+T V A+K + ++ V+ E + +L H
Sbjct: 584 VLGKGTYGTVYAARD----------KQTQVRIAIKEVPEKNSQDVQPLHEEIKLHSQLRH 633
Query: 199 PNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIY--QILLAL 256
NI+R SC + G IF + + GG L L P+ + ES + Y QIL L
Sbjct: 634 RNIVRYLGSCSEN-GFFKIFMEQVPGGSLSDLLETK--WGPLKDNESTMAFYSKQILEGL 690
Query: 257 KFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAP 316
K+LH IVHRD+K DN+L++T K+ +DFG +K L++ T GT +Y AP
Sbjct: 691 KYLHEQDIVHRDIKGDNVLVNTYSGVVKI--SDFGTSKRLAR-INPMTETFTGTLQYMAP 747
Query: 317 EVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASII 376
EV +D GY DIWS G M TG PF GS + +
Sbjct: 748 EV-----------------IDQGVRGYGPAADIWSFGCTNVEMATGKPPFIELGSAHAAM 790
Query: 377 KNVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVE 426
V K + + ++ +AK+F+ +C +S +R + L +++
Sbjct: 791 FKVGFYKKHPNIPE--ELSANAKNFILRCFAISVMDRPSASQLLEDPFLQ 838
>SPBC17F3.02 [T] KOG0201 Serine/threonine protein kinase
Length = 652
Score = 99.0 bits (245), Expect = 1e-20
Identities = 86/305 (28%), Positives = 139/305 (45%), Gaps = 48/305 (15%)
Query: 144 IVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMV---KEATILEKLNHP- 199
+VG G++G V + + K+TV+ + ++T + + KE +L +L
Sbjct: 15 LVGRGSYGAV-------YRGICNLTKETVAIKILNLDTDEDEVSDIQKEVAVLSELKQSD 67
Query: 200 --NIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALK 257
NII+ H S + N++I D GG + + + G PISE +I+ + L ALK
Sbjct: 68 VENIIKYHGSYLVGT-NLWIIMDYCHGGSVRTLMEAG----PISEPCISLILRETLQALK 122
Query: 258 FLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPE 317
F+H GI+HRD+K NIL+ V L DFG+A EL+ N ++R+ T +GTP + APE
Sbjct: 123 FIHHAGIIHRDIKAANILV---SMSGNVKLCDFGVAAELNINRRKRI-TFIGTPYWMAPE 178
Query: 318 VGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIK 377
V D Y+ DIWSLG+ + + TG P + ++
Sbjct: 179 V------------------IRDGQEYNVMADIWSLGITAYEIATGSPPHAKEDPFRAVYL 220
Query: 378 NVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKHT----SQLE 433
T + K F+ CLQ R D E L ++++++ S+L
Sbjct: 221 IAHTAPPRLNGN----FSALLKEFIASCLQDVPQRRLDSSELLKSKFIKQYSRMSISELT 276
Query: 434 RIYKK 438
+ K+
Sbjct: 277 NVVKR 281
>Hs5453966 [T] KOG0583 Serine/threonine protein kinase
Length = 552
Score = 99.0 bits (245), Expect = 1e-20
Identities = 81/290 (27%), Positives = 132/290 (44%), Gaps = 48/290 (16%)
Query: 145 VGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMV-------KEATILEKLN 197
+G GTFG V + E Q+ V AVK++N K R + +E L+
Sbjct: 22 LGVGTFGKVKIGE-------HQLTGHKV--AVKILNRQKIRSLDVVGKIKREIQNLKLFR 72
Query: 198 HPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALK 257
HP+II+++Q + + ++ + +SGG+LF Y+ K + E E+ + QIL A+
Sbjct: 73 HPHIIKLYQ-VISTPTDFFMVMEYVSGGELFDYICKHG---RVEEMEARRLFQQILSAVD 128
Query: 258 FLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPE 317
+ H + +VHRDLK +N+LL + +ADFG++ +S E + T G+P Y APE
Sbjct: 129 YCHRHMVVHRDLKPENVLL---DAHMNAKIADFGLSNMMSDG--EFLRTSCGSPNYTAPE 183
Query: 318 VGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIK 377
V +Y + DIWS GVI + +L G PF D ++ K
Sbjct: 184 V---ISGRLYAG---------------PEVDIWSCGVILYALLCGTLPF-DDEHVPTLFK 224
Query: 378 NVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEK 427
+R G + S + + LQV R +++ W ++
Sbjct: 225 KIRGGVFYIPE----YLNRSVATLLMHMLQVDPLKRATIKDIREHEWFKQ 270
>Hs4758194 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 372
Score = 99.0 bits (245), Expect = 1e-20
Identities = 62/246 (25%), Positives = 124/246 (50%), Gaps = 25/246 (10%)
Query: 183 KTRMVKEATILEKLNH-PNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPIS 241
+ ++ E +LE P +I +H+ + + + + +GG++FS L + +S
Sbjct: 74 RAEILHEIAVLELAKSCPRVINLHE-VYENTSEIILILEYAAGGEIFS-LCLPELAEMVS 131
Query: 242 ETESLIIIYQILLALKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTK 301
E + + +I QIL + +LH N IVH DLK NILL + P + + DFG+++++ +
Sbjct: 132 ENDVIRLIKQILEGVYYLHQNNIVHLDLKPQNILLSSIYPLGDIKIVDFGMSRKIGHACE 191
Query: 302 ERMHTVVGTPEYCAPEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLT 361
+ ++GTPEY APE+ DP + D+W++G+I +++LT
Sbjct: 192 --LREIMGTPEYLAPEI---------------LNYDP----ITTATDMWNIGIIAYMLLT 230
Query: 362 GISPFYGDGSEASIIKNVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALH 421
SPF G+ ++ + + N+ ++++ + +++ A F++ L + R E L
Sbjct: 231 HTSPFVGEDNQETYL-NISQVNVDYSEETFSSVSQLATDFIQSLLVKNPEKRPTAEICLS 289
Query: 422 QVWVEK 427
W+++
Sbjct: 290 HSWLQQ 295
>CE27670 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 572
Score = 99.0 bits (245), Expect = 1e-20
Identities = 89/329 (27%), Positives = 150/329 (45%), Gaps = 41/329 (12%)
Query: 94 VPYLLSNQDVIQLPNGAKFKFSAVKSETMSQFMTGLRIKSEWDRWKIVPRIVGSGTFGHV 153
+P L Q +Q G K K +E +++ T + I + +++ V +I GSG G V
Sbjct: 252 IPDLSKGQFGVQA-RGQKAKKKMTDAEVLTKLRTIVSIGNPDRKYRKVDKI-GSGASGSV 309
Query: 154 LVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKLNHPNIIRIHQSCVDALG 213
A ++ + + +VA K ++ + K ++ E ++ + H NI+ S +
Sbjct: 310 YTA--IEISTEAEVAIKQMNLKDQ---PKKELIINEILVMRENKHANIVNYLDSYL-VCD 363
Query: 214 NVYIFQDLISGGDLFSYLAKGDCLVPISETESLI--IIYQILLALKFLHSNGIVHRDLKL 271
+++ + ++GG L D + + +I + ++L AL+FLHS ++HRD+K
Sbjct: 364 ELWVVMEYLAGGSLT------DVVTECQMEDGIIAAVCREVLQALEFLHSRHVIHRDIKS 417
Query: 272 DNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKADRNIYRSFS 331
DNILL V L DFG +LS ++R T+VGTP + APEV +
Sbjct: 418 DNILLGMD---GSVKLTDFGFCAQLSPEQRKRT-TMVGTPYWMAPEVVTRKQ-------- 465
Query: 332 RTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVRTGKLNFTARQW 391
Y K D+WSLG++ M+ G P+ + +I GK +F R
Sbjct: 466 -----------YGPKVDVWSLGIMAIEMVEGEPPYLNENPLRAIYLIATNGKPDFPGRD- 513
Query: 392 IAITDSAKSFVKKCLQVSTFNRCDVEEAL 420
++T K FV L+V NR + L
Sbjct: 514 -SMTLLFKDFVDSALEVQVENRWSASQLL 541
>At5g10930 [T] KOG0583 Serine/threonine protein kinase
Length = 445
Score = 99.0 bits (245), Expect = 1e-20
Identities = 78/296 (26%), Positives = 136/296 (45%), Gaps = 51/296 (17%)
Query: 143 RIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKT--------RMVKEATILE 194
R++G GTF V +++ + + V A+KVIN + ++ +E +I++
Sbjct: 16 RLLGKGTFAKVYYGKEI-------IGGECV--AIKVINKDQVMKRPGMMEQIKREISIMK 66
Query: 195 KLNHPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILL 254
+ HPNI+ + + ++ + + GG+LF ++KG + E + Q++
Sbjct: 67 LVRHPNIVELKEVMATKT-KIFFVMEFVKGGELFCKISKGK----LHEDAARRYFQQLIS 121
Query: 255 ALKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKE-RMHTVVGTPEY 313
A+ + HS G+ HRDLK +N+LL + + ++DFG++ Q ++ +HT GTP Y
Sbjct: 122 AVDYCHSRGVSHRDLKPENLLL---DENGDLKISDFGLSALPEQILQDGLLHTQCGTPAY 178
Query: 314 CAPEVGFKADRNIYRSFSRTATLDPDNNGYD-SKCDIWSLGVITHIMLTGISPFYGDGSE 372
APEV K GYD +K DIWS GV+ +++L G PF +
Sbjct: 179 VAPEVLKK-------------------KGYDGAKADIWSCGVVLYVLLAGCLPFQDENLM 219
Query: 373 ASIIKNVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKH 428
K R +F W + A+ + K L V R + + W+ K+
Sbjct: 220 NMYRKIFRA---DFEFPPW--FSPEARRLISKLLVVDPDRRISIPAIMRTPWLRKN 270
>At1g48490 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1244
Score = 99.0 bits (245), Expect = 1e-20
Identities = 75/253 (29%), Positives = 115/253 (44%), Gaps = 52/253 (20%)
Query: 141 VPRIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKLNHPN 200
V + + G FGHV++A K + A K + A + A ++ E IL +P
Sbjct: 830 VMKSISRGAFGHVILARK--NTTGDLFAIKVLRKADMIRKNAVESILAERDILINARNPF 887
Query: 201 IIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLH 260
++R S + N+Y+ + ++GGD +S L K CL E + + I +++LAL++LH
Sbjct: 888 VVRFFYSFTCS-ENLYLVMEYLNGGDFYSMLRKIGCL---DEANARVYIAEVVLALEYLH 943
Query: 261 SNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAK-ELSQNTK------------------ 301
S G+VHRDLK DN+L+ V L DFG++K L NT
Sbjct: 944 SEGVVHRDLKPDNLLIAHD---GHVKLTDFGLSKVGLINNTDDLSGPVSSATSLLVEEKP 1000
Query: 302 -----ERMHTVVGTPEYCAPEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVIT 356
+ + VGTP+Y APE+ G+ + D WS+G+I
Sbjct: 1001 KLPTLDHKRSAVGTPDYLAPEILL-------------------GTGHGATADWWSVGIIL 1041
Query: 357 HIMLTGISPFYGD 369
+ L GI PF D
Sbjct: 1042 YEFLVGIPPFNAD 1054
>At4g33950 [T] KOG0583 Serine/threonine protein kinase
Length = 357
Score = 98.6 bits (244), Expect = 2e-20
Identities = 77/302 (25%), Positives = 131/302 (42%), Gaps = 35/302 (11%)
Query: 129 LRIKSEWDRWKIVPRIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVK 188
L I + DR+++V + +GSG FG + D VA K + K+ K ++
Sbjct: 12 LPIMHDSDRYELV-KDIGSGNFGVARLMR--DKQSNELVAVKYIERGEKIDENVKREIIN 68
Query: 189 EATILEKLNHPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLII 248
+ L HPNI+R + + ++ I + SGG+LF + SE E+
Sbjct: 69 HRS----LRHPNIVRFKEVILTPT-HLAIVMEYASGGELFERICNAG---RFSEDEARFF 120
Query: 249 IYQILLALKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVV 308
Q++ + + H+ + HRDLKL+N LL P ++ + DFG +K +++ + + V
Sbjct: 121 FQQLISGVSYCHAMQVCHRDLKLENTLL-DGSPAPRLKICDFGYSKSSVLHSQPK--STV 177
Query: 309 GTPEYCAPEVGFKADRNIYRSFSRTATLDPDNNGYDSK-CDIWSLGVITHIMLTGISPFY 367
GTP Y APEV K + YD K D+WS GV ++ML G PF
Sbjct: 178 GTPAYIAPEVLLKKE-------------------YDGKVADVWSCGVTLYVMLVGAYPFE 218
Query: 368 GDGSEASIIKNV-RTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVE 426
+ K + R + + ++ I+ + + + R + E + W
Sbjct: 219 DPEEPKNFRKTIHRILNVQYAIPDYVHISPECRHLISRIFVADPAKRISIPEIRNHEWFL 278
Query: 427 KH 428
K+
Sbjct: 279 KN 280
>At2g38490 [T] KOG0583 Serine/threonine protein kinase
Length = 431
Score = 98.6 bits (244), Expect = 2e-20
Identities = 83/315 (26%), Positives = 143/315 (45%), Gaps = 46/315 (14%)
Query: 143 RIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKLNHPNII 202
+++GSG F V AE + + + K +K TA + +E +++ +L HP+I+
Sbjct: 32 KLLGSGAFAKVYQAEDLQNGGESVAIKVVQKKRLKDGLTAHVK--REISVMRRLRHPHIV 89
Query: 203 RIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIY--QILLALKFLH 260
+ + +Y +L GG+LFS + TESL Y Q++ A+++ H
Sbjct: 90 LLSEVLATKT-KIYFVMELAKGGELFSRVTSNRF------TESLSRKYFRQLISAVRYCH 142
Query: 261 SNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERM-HTVVGTPEYCAPEVG 319
+ G+ HRDLK +N+LL + + ++DFG++ Q + M HT+ GTP Y APE+
Sbjct: 143 ARGVFHRDLKPENLLL---DENRDLKVSDFGLSAMKEQIHPDGMLHTLCGTPAYVAPELL 199
Query: 320 FKADRNIYRSFSRTATLDPDNNGYD-SKCDIWSLGVITHIMLTGISPFYGDGSEASIIKN 378
K GYD SK DIWS GV+ ++ G PF D + + +
Sbjct: 200 LK-------------------KGYDGSKADIWSCGVVLFLLNAGYLPF-RDPNIMGLYRK 239
Query: 379 VRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKHTSQLERIYKK 438
+ K + W + + +++ L+ + R VEE L W E
Sbjct: 240 IH--KAQYKLPDW--TSSDLRKLLRRLLEPNPELRITVEEILKDPWFNHGVDPSE----- 290
Query: 439 KVLQLSSDCIKIDEN 453
++ + +D ++EN
Sbjct: 291 -IIGIQADDYDLEEN 304
>At2g17290 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 544
Score = 98.6 bits (244), Expect = 2e-20
Identities = 79/284 (27%), Positives = 128/284 (44%), Gaps = 30/284 (10%)
Query: 143 RIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKL-NHPNI 201
R +G G FG + + + A K++S + + +E I+ L H NI
Sbjct: 89 RKLGQGQFGTTYLCTDIATGV--DYACKSISKRKLISKEDVEDVRREIQIMHHLAGHKNI 146
Query: 202 IRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHS 261
+ I + D L V+I +L +GG+LF + SE ++ + I+ ++ HS
Sbjct: 147 VTIKGAYEDPL-YVHIVMELCAGGELFDRIIHRG---HYSERKAAELTKIIVGVVEACHS 202
Query: 262 NGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFK 321
G++HRDLK +N LL + + DFG++ + VVG+P Y APEV K
Sbjct: 203 LGVMHRDLKPENFLLVNKDDDFSLKAIDFGLSVFFKPG--QIFKDVVGSPYYVAPEVLLK 260
Query: 322 ADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVRT 381
Y + D+W+ GVI +I+L+G+ PF+ + ++ I V
Sbjct: 261 H--------------------YGPEADVWTAGVILYILLSGVPPFWAE-TQQGIFDAVLK 299
Query: 382 GKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWV 425
G ++F W I+DSAK ++K L S R E L W+
Sbjct: 300 GYIDFDTDPWPVISDSAKDLIRKMLCSSPSERLTAHEVLRHPWI 343
>At1g78290 [T] KOG0583 Serine/threonine protein kinase
Length = 343
Score = 98.6 bits (244), Expect = 2e-20
Identities = 81/296 (27%), Positives = 133/296 (44%), Gaps = 37/296 (12%)
Query: 136 DRWKIVPRIVGSGTFGHVLVAEKV-DHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILE 194
+R++IV + +GSG FG VA+ V D K A K + K+ + ++ +++
Sbjct: 2 ERYEIV-KDIGSGNFG---VAKLVRDKFSKELFAVKFIERGQKIDEHVQREIMNHRSLI- 56
Query: 195 KLNHPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILL 254
HPNIIR + + A ++ + + +GG+LF + SE E+ Q++
Sbjct: 57 ---HPNIIRFKEVLLTAT-HLALVMEYAAGGELFGRICSAG---RFSEDEARFFFQQLIS 109
Query: 255 ALKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYC 314
+ + HS I HRDLKL+N LL E +V + DFG +K +++ + T VGTP Y
Sbjct: 110 GVNYCHSLQICHRDLKLENTLLDGSE-APRVKICDFGYSKSGVLHSQPK--TTVGTPAYI 166
Query: 315 APEVGFKADRNIYRSFSRTATLDPDNNGYDSK-CDIWSLGVITHIMLTGISPFYGDGSEA 373
APEV YD K D+WS GV ++ML G PF
Sbjct: 167 APEV-------------------LSTKEYDGKIADVWSCGVTLYVMLVGAYPFEDPSDPK 207
Query: 374 SIIKNV-RTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKH 428
K + R K + ++ ++D + + + + R +EE + W K+
Sbjct: 208 DFRKTIGRILKAQYAIPDYVRVSDECRHLLSRIFVANPEKRITIEEIKNHSWFLKN 263
>YNL298w [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 842
Score = 98.2 bits (243), Expect = 2e-20
Identities = 86/341 (25%), Positives = 145/341 (42%), Gaps = 46/341 (13%)
Query: 102 DVIQLPNGAKFKFSAVKSETMSQFMTGLR---IKSEWDRWKIVPRIVGSGTFGHVLVAEK 158
DV Q AK K A + + ++ M+ L+ + ++ + V G G G V +AE+
Sbjct: 506 DVAQPGGVAKPKKPARPTMSTAEIMSKLKKVTVNADPSQCFKVIEKAGQGASGSVYLAER 565
Query: 159 V----DHNMKRQVA----------KKTVSYAVKVINTAKTRMVKEATILEKLNHPNIIRI 204
+ NM + K + V K +V E +++ H NI+
Sbjct: 566 THIPTESNMIELINNDIDEPHVGDKVAIKQMVLSKQPRKELIVNEILVMKDSRHKNIVNF 625
Query: 205 HQSCVDALGNVYIFQDLISGGDLFSYLAKG----DCLVPISETESLIIIYQILLALKFLH 260
++ + ++++ + + GG L + + P++E + I+ + LKFLH
Sbjct: 626 LEAYLRTDDDLWVVMEFMEGGSLTDIIENSPTNDNSHSPLTEPQIAYIVRETCQGLKFLH 685
Query: 261 SNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGF 320
I+HRD+K DN+LL T +V + DFG L+ +R T+VGTP + APEV
Sbjct: 686 DKHIIHRDIKSDNVLLDTR---ARVKITDFGFCARLTDKRSKRA-TMVGTPYWMAPEVVK 741
Query: 321 KADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVR 380
+ + YD K D+WSLG++T ML G P+ + ++
Sbjct: 742 QRE-------------------YDEKIDVWSLGIMTIEMLEGEPPYLNEDPLKALYLIAT 782
Query: 381 TGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALH 421
G + +++ K F+ CL V R EE LH
Sbjct: 783 NGTPKLKHPESLSL--EIKRFLSVCLCVDVRYRASTEELLH 821
>YHL007c [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 939
Score = 98.2 bits (243), Expect = 2e-20
Identities = 84/318 (26%), Positives = 143/318 (44%), Gaps = 46/318 (14%)
Query: 145 VGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTR----MVKEATILEKLNHPN 200
+G G G V A ++ N VS A+K +N K ++ E +++ HPN
Sbjct: 626 IGQGASGGVYTAYEIGTN---------VSVAIKQMNLEKQPKKELIINEILVMKGSKHPN 676
Query: 201 IIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLH 260
I+ S V G++++ + + GG L + C+ ++E + + + L L+FLH
Sbjct: 677 IVNFIDSYV-LKGDLWVIMEYMEGGSLTDVVTH--CI--LTEGQIGAVCRETLSGLEFLH 731
Query: 261 SNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGF 320
S G++HRD+K DNILL + L DFG ++++ +R T+VGTP + APEV
Sbjct: 732 SKGVLHRDIKSDNILLSME---GDIKLTDFGFCAQINELNLKRT-TMVGTPYWMAPEVVS 787
Query: 321 KADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVR 380
+ + Y K DIWSLG++ M+ G P+ + ++
Sbjct: 788 RKE-------------------YGPKVDIWSLGIMIIEMIEGEPPYLNETPLRALYLIAT 828
Query: 381 TGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVW---VEKHTSQLERIYK 437
G + ++ S K F+ CL V +R E LH + + + S L + K
Sbjct: 829 NGTPKLKEPE--NLSSSLKKFLDWCLCVEPEDRASATELLHDEYITEIAEANSSLAPLVK 886
Query: 438 KKVLQLSSDCIKIDENID 455
L+ ++ + DE+ D
Sbjct: 887 LARLKKVAENMDADEDND 904
>YAR019c [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 974
Score = 98.2 bits (243), Expect = 2e-20
Identities = 84/313 (26%), Positives = 144/313 (45%), Gaps = 43/313 (13%)
Query: 143 RIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKLNHPNII 202
+++G G++G +V + ++ + + VA K V Y + ++ E ++L+ LNH NI+
Sbjct: 29 QVIGRGSYG--VVYKAINKHTDQVVAIKEVVYEN---DEELNDIMAEISLLKNLNHNNIV 83
Query: 203 RIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHSN 262
+ H + +YI + + G L +++ +SE ES + Q LL LK+LH
Sbjct: 84 KYH-GFIRKSYELYILLEYCANGSLRRLISRSS--TGLSENESKTYVTQTLLGLKYLHGE 140
Query: 263 GIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFKA 322
G++HRD+K NILL V LADFG++ ++ + T+ GT + APE+
Sbjct: 141 GVIHRDIKAANILLSAD---NTVKLADFGVSTIVNSSAL----TLAGTLNWMAPEI---- 189
Query: 323 DRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVRTG 382
N G + DIWSLG MLT +P Y + ++A+I V
Sbjct: 190 ---------------LGNRGASTLSDIWSLGATVVEMLTK-NPPYHNLTDANIYYAVE-- 231
Query: 383 KLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKHTSQLERIYKKKVLQ 442
N T + ++ K F+ KC + + R ++ L VW+ + E + K+ +
Sbjct: 232 --NDTYYPPSSFSEPLKDFLSKCFVKNMYKRPTADQLLKHVWI----NSTENVKVDKLNK 285
Query: 443 LSSDCIKIDENID 455
D D + D
Sbjct: 286 FKEDFTDADYHWD 298
>Hs7662210 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 1036
Score = 98.2 bits (243), Expect = 2e-20
Identities = 75/237 (31%), Positives = 112/237 (46%), Gaps = 38/237 (16%)
Query: 144 IVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKLNHPNIIR 203
+VG G F V H K S K ++ ++ + KE IL++L H NI+
Sbjct: 14 LVGHGAFAVVFRGR---HRQKTDWEVAIKSINKKNLSKSQILLGKEIKILKELQHENIVA 70
Query: 204 IHQSCVDALGN-VYIFQDLISGGDLFSYL-AKGDCLVPISETESLIIIYQILLALKFLHS 261
++ V L N V++ + +GGDL YL AKG +SE + ++QI A++ LHS
Sbjct: 71 LYD--VQELPNSVFLVMEYCNGGDLADYLQAKGT----LSEDTIRVFLHQIAAAMRILHS 124
Query: 262 NGIVHRDLKLDNILL------HTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCA 315
GI+HRDLK NILL + ++ +ADFG A+ L N T+ G+P Y A
Sbjct: 125 KGIIHRDLKPQNILLSYANRRKSSVSGIRIKIADFGFARYLHSNMMAA--TLCGSPMYMA 182
Query: 316 PEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSE 372
PEV + YD+K D+WS+G + + L G PF + +
Sbjct: 183 PEVIM-------------------SQHYDAKADLWSIGTVIYQCLVGKPPFQANSPQ 220
>Hs21361433 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 970
Score = 98.2 bits (243), Expect = 2e-20
Identities = 75/290 (25%), Positives = 140/290 (47%), Gaps = 33/290 (11%)
Query: 141 VPRIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKLNHPN 200
V ++G G+F V AE + + +VA K + R+ E I +L HP+
Sbjct: 14 VGNLLGKGSFAGVYRAESIHSGL--EVAIKMIDKKAMYKAGMVQRVQNEVKIHCQLKHPS 71
Query: 201 IIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLH 260
I+ ++ D+ VY+ ++ G++ YL + P SE E+ ++QI+ + +LH
Sbjct: 72 ILELYNYFEDS-NYVYLVLEMCHNGEMNRYLKNR--VKPFSENEARHFMHQIITGMLYLH 128
Query: 261 SNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGF 320
S+GI+HRDL L N+LL + +ADFG+A +L E+ +T+ GTP Y +PE+
Sbjct: 129 SHGILHRDLTLSNLLLTRN---MNIKIADFGLATQLKM-PHEKHYTLCGTPNYISPEIAT 184
Query: 321 KADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVR 380
++ + + D+WSLG + + +L G PF D + ++ K V
Sbjct: 185 RSAHGL-------------------ESDVWSLGCMFYTLLIGRPPFDTDTVKNTLNKVVL 225
Query: 381 TGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKHTS 430
++ +++I AK + + L+ + +R + L ++ +++S
Sbjct: 226 A---DYEMPTFLSI--EAKDLIHQLLRRNPADRLSLSSVLDHPFMSRNSS 270
>At5g01820 [T] KOG0583 Serine/threonine protein kinase
Length = 442
Score = 98.2 bits (243), Expect = 2e-20
Identities = 78/296 (26%), Positives = 137/296 (45%), Gaps = 50/296 (16%)
Query: 141 VPRIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTR-------MVKEATIL 193
V ++VG G F KV H + S A+KV++ + + + +E I+
Sbjct: 24 VGKLVGCGAFA------KVYHGRSTATGQ---SVAIKVVSKQRLQKGGLNGNIQREIAIM 74
Query: 194 EKLNHPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQIL 253
+L HP+I+R+ + + ++ + GG+LF+ ++KG +S Q++
Sbjct: 75 HRLRHPSIVRLFE-VLATKSKIFFVMEFAKGGELFAKVSKGRFCEDLSRR----YFQQLI 129
Query: 254 LALKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKE-RMHTVVGTPE 312
A+ + HS GI HRDLK +N+LL + + ++DFG++ Q + +HT+ GTP
Sbjct: 130 SAVGYCHSRGIFHRDLKPENLLL---DEKLDLKISDFGLSALTDQIRPDGLLHTLCGTPA 186
Query: 313 YCAPEVGFKADRNIYRSFSRTATLDPDNNGYD-SKCDIWSLGVITHIMLTGISPFYGDGS 371
Y APEV K GYD +K DIWS G+I ++ G PF D +
Sbjct: 187 YVAPEVLAK-------------------KGYDGAKIDIWSCGIILFVLNAGYLPF-NDHN 226
Query: 372 EASIIKNVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEK 427
+ + + G+ F +W + + + + L + R +EE +H W ++
Sbjct: 227 LMVMYRKIYKGE--FRIPKW--TSPDLRRLLTRLLDTNPQTRITIEEIIHDPWFKQ 278
>HsM7657627 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 970
Score = 97.8 bits (242), Expect = 3e-20
Identities = 75/290 (25%), Positives = 140/290 (47%), Gaps = 33/290 (11%)
Query: 141 VPRIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKLNHPN 200
V ++G G+F V AE + + +VA K + R+ E I +L HP+
Sbjct: 14 VGNLLGKGSFAGVYRAESIHTGL--EVAIKMIDKKAMYKAGMVQRVKNEVKIHCQLKHPS 71
Query: 201 IIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLH 260
I+ ++ D+ VY+ ++ G++ YL + P SE E+ ++QI+ + +LH
Sbjct: 72 ILELYNYFEDS-NYVYLVLEMCHNGEMNRYLKNR--VKPFSENEARHFMHQIITGMLYLH 128
Query: 261 SNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGF 320
S+GI+HRDL L N+LL + +ADFG+A +L E+ +T+ GTP Y +PE+
Sbjct: 129 SHGILHRDLTLSNLLLTRN---MNIKIADFGLATQLKM-PHEKHYTLCGTPNYISPEIAT 184
Query: 321 KADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVR 380
++ + + D+WSLG + + +L G PF D + ++ K V
Sbjct: 185 RSAHGL-------------------ESDVWSLGCMFYTLLIGRPPFDTDTVKNTLNKVVL 225
Query: 381 TGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKHTS 430
++ +++I AK + + L+ + +R + L ++ +++S
Sbjct: 226 A---DYEMPTFLSI--EAKDLIHQLLRRNPADRLSLSSVLDHPFMSRNSS 270
>Hs4885583 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1354
Score = 97.8 bits (242), Expect = 3e-20
Identities = 82/290 (28%), Positives = 139/290 (47%), Gaps = 55/290 (18%)
Query: 89 VLSRDVPYLLSNQDVIQLPNGAKFKFSAVKSETMSQFMTGLRIKSEWDRWKIVPRIVGSG 148
V D P L N+++ + K + ++ LR+K+E +++V +++G G
Sbjct: 38 VYDLDFPALRKNKNIDNFLSRYKDTINKIRD---------LRMKAE--DYEVV-KVIGRG 85
Query: 149 TFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVK---------EATILEKLNHP 199
FG V + V H R+V YA+K+++ K M+K E I+ N P
Sbjct: 86 AFGEV---QLVRHKSTRKV------YAMKLLS--KFEMIKRSDSAFFWEERDIMAFANSP 134
Query: 200 NIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFL 259
++++ + D +Y+ + + GGDL + ++ D + E + +++LAL +
Sbjct: 135 WVVQLFYAFQDDR-YLYMVMEYMPGGDLVNLMSNYD----VPEKWARFYTAEVVLALDAI 189
Query: 260 HSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVG 319
HS G +HRD+K DN+LL + + LADFG ++++ R T VGTP+Y +PEV
Sbjct: 190 HSMGFIHRDVKPDNMLL---DKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDYISPEVL 246
Query: 320 FKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGD 369
+ Y Y +CD WS+GV + ML G +PFY D
Sbjct: 247 KSQGGDGY---------------YGRECDWWSVGVFLYEMLVGDTPFYAD 281
>CE22045 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 580
Score = 97.8 bits (242), Expect = 3e-20
Identities = 92/341 (26%), Positives = 152/341 (43%), Gaps = 47/341 (13%)
Query: 143 RIVGSGTFGHVLVAEKVDHNMKRQV-AKKTVSYAVKVINTAKTRMVK-EATILEKLNHPN 200
+++G G +G V K + Q+ A K + A V N T K E ILE + P
Sbjct: 87 KVLGKGGYGKVFQVRKTTGSDNGQIFAMKVLQKATIVRNQKDTAHTKAERNILEAVKSPF 146
Query: 201 IIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLH 260
I + + G +Y+ + +SGG+LF +L + + E + + +I+++L+ LH
Sbjct: 147 ICDLLYAFQTG-GKLYLILEYLSGGELFMHLEREGMFM---ENVAKFYLSEIVVSLEHLH 202
Query: 261 SNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGF 320
GI++RDLK +NILL + V L DFG+ KE + ++ HT GT EY APE+
Sbjct: 203 QQGIIYRDLKPENILL---DAYGHVKLTDFGLCKEEIEG-DQKTHTFCGTIEYMAPEILM 258
Query: 321 KADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVR 380
+ G+ D WSLG + MLTG PF + +I K +
Sbjct: 259 RC-------------------GHGKAVDWWSLGALMFDMLTGGPPFTAENRRKTIDK-IL 298
Query: 381 TGKLNFTARQWIAITDSAKSFVKKCLQVSTFNR-----CDVEEALHQVWVEKHTSQLERI 435
G+L A +++ A+ +KK L+ R D EE + + T+ +
Sbjct: 299 KGRLTLPA----YLSNEARDLIKKLLKRHVDTRLGAGLSDAEEIKSHAFFK--TTDWNLV 352
Query: 436 YKKKVLQLSSDCIKIDENIDTFAVVKHKLPKSVKLSPEKNP 476
Y +++ I+ DE+ F + K++P +P
Sbjct: 353 YARQLEAPFKPNIENDEDTSLFDA------RFTKMTPVDSP 387
>At4g35310 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 556
Score = 97.8 bits (242), Expect = 3e-20
Identities = 76/284 (26%), Positives = 131/284 (45%), Gaps = 30/284 (10%)
Query: 143 RIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVKEATILEKL-NHPNI 201
R +G G FG + ++ + A K++S + + +E I+ L H +I
Sbjct: 101 RKLGQGQFGTTYLCTEIASGV--DYACKSISKRKLISKEDVEDVRREIQIMHHLAGHGSI 158
Query: 202 IRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLALKFLHS 261
+ I + D+L V+I +L +GG+LF + + SE ++ + I+ ++ HS
Sbjct: 159 VTIKGAYEDSL-YVHIVMELCAGGELFDRIIQRG---HYSERKAAELTKIIVGVVEACHS 214
Query: 262 NGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCAPEVGFK 321
G++HRDLK +N LL + + DFG++ + VVG+P Y APEV K
Sbjct: 215 LGVMHRDLKPENFLLVNKDDDFSLKAIDFGLSVFFKPG--QIFTDVVGSPYYVAPEVLLK 272
Query: 322 ADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYGDGSEASIIKNVRT 381
Y + D+W+ GVI +I+L+G+ PF+ + ++ I V
Sbjct: 273 R--------------------YGPEADVWTAGVILYILLSGVPPFWAE-TQQGIFDAVLK 311
Query: 382 GKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWV 425
G ++F + W I+DSAK +++ L R E L W+
Sbjct: 312 GYIDFESDPWPVISDSAKDLIRRMLSSKPAERLTAHEVLRHPWI 355
>At4g21940 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 554
Score = 97.8 bits (242), Expect = 3e-20
Identities = 68/240 (28%), Positives = 120/240 (49%), Gaps = 30/240 (12%)
Query: 188 KEATILEKLN-HPNIIRIHQSCVDALGNVYIFQDLISGGDLFS-YLAKGDCLVPISETES 245
+E I++ L+ NI+ I + D ++++ +L G +LF +A+G SE +
Sbjct: 149 REIQIMQYLSGQENIVEIKGAYEDRQ-SIHLVMELCGGSELFDRIIAQGH----YSEKAA 203
Query: 246 LIIIYQILLALKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMH 305
+I +L ++ H G++HRDLK +N LL + + + DFG++ + + R
Sbjct: 204 AGVIRSVLNVVQICHFMGVIHRDLKPENFLLASTDENAMLKATDFGLSVFIEEGKVYR-- 261
Query: 306 TVVGTPEYCAPEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISP 365
+VG+ Y APEV + RS Y + DIWS G+I +I+L G+ P
Sbjct: 262 DIVGSAYYVAPEV-------LRRS-------------YGKEIDIWSAGIILYILLCGVPP 301
Query: 366 FYGDGSEASIIKNVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWV 425
F+ + +E I + G+++F ++ W +I++SAK V+K L R +AL W+
Sbjct: 302 FWSE-TEKGIFNEIIKGEIDFDSQPWPSISESAKDLVRKLLTKDPKQRISAAQALEHPWI 360
>YOR233w [T] KOG0583 Serine/threonine protein kinase
Length = 800
Score = 97.4 bits (241), Expect = 4e-20
Identities = 80/304 (26%), Positives = 138/304 (45%), Gaps = 41/304 (13%)
Query: 140 IVPRIVGSGTFGHVLVA---EKVDHNMKRQVAKKTVSY-AVKVINTAKTRMVKEATILEK 195
I+ +G G FG V + + + +QVA K + +K + ++ +E L+
Sbjct: 47 IIGSTLGEGEFGKVKLGWTKASSSNEVPKQVAIKLIRRDTIKKDADKEIKIYREINALKH 106
Query: 196 LNHPNIIRIHQSCVDALGNVYIFQDLISGGDLFSYLAKGDCLVPISETESLIIIYQILLA 255
L HPNII + + ++ + I + +SGG+ + Y+ + L E+ + + Q++
Sbjct: 107 LTHPNIIYLEEVLQNSK-YIGIVLEFVSGGEFYKYIQRKRRL---KESSACRLFAQLISG 162
Query: 256 LKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVVGTPEYCA 315
+ ++H G+VHRDLKL+N+LL E +V+ DFG E ++ E M T G+P Y A
Sbjct: 163 VNYMHYKGLVHRDLKLENLLLDKHE---NLVITDFGFVNEFFED-NELMKTSCGSPCYAA 218
Query: 316 PEVGFKADRNIYRSFSRTATLDPDNNGYDS-KCDIWSLGVITHIMLTGISPFYGDGSE-- 372
PE L Y++ K D+WS GVI + ML G P+ D
Sbjct: 219 PE------------------LVVSTKAYEARKADVWSCGVILYAMLAGYLPWDDDHENPT 260
Query: 373 ----ASIIKNVRTGKLNFTARQWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWVEKH 428
A + K + L F IT + +++ L + R +++ VW++ H
Sbjct: 261 GDDIARLYKYITQTPLKFPE----YITPIPRDLLRRILVPNPRRRINLQTIKRHVWLKPH 316
Query: 429 TSQL 432
+ L
Sbjct: 317 EAFL 320
>Hs7661994 [T] KOG0579 Ste20-like serine/threonine protein kinase
Length = 1152
Score = 97.4 bits (241), Expect = 4e-20
Identities = 95/334 (28%), Positives = 158/334 (46%), Gaps = 51/334 (15%)
Query: 136 DRWKIVPRIVGSGTFGHVLVAEKVDHNMKRQVAKKTVSYAVKVINTAKTRMVK----EAT 191
D W+I+ + G G FG V K Q + +V A KVI+T ++ E
Sbjct: 32 DFWEIIGEL-GDGAFGKVY---------KAQNKETSVLAAAKVIDTKSEEELEDYMVEID 81
Query: 192 ILEKLNHPNIIRIHQSCVDAL---GNVYIFQDLISGGDLFSYLAKGDCLVPISETESLII 248
IL +HPNI+++ +DA N++I + +GG + + + + + P++E++ ++
Sbjct: 82 ILASCDHPNIVKL----LDAFYYENNLWILIEFCAGGAVDAVMLELER--PLTESQIQVV 135
Query: 249 IYQILLALKFLHSNGIVHRDLKLDNILLHTPEPCTKVVLADFGIAKELSQNTKERMHTVV 308
Q L AL +LH N I+HRDLK NIL + LADFG++ + + T +R + +
Sbjct: 136 CKQTLDALNYLHDNKIIHRDLKAGNILFTLD---GDIKLADFGVSAK-NTRTIQRRDSFI 191
Query: 309 GTPEYCAPEVGFKADRNIYRSFSRTATLDPDNNGYDSKCDIWSLGVITHIMLTGISPFYG 368
GTP + APEV T+ P YD K D+WSLG IT I + I P +
Sbjct: 192 GTPYWMAPEV----------VMCETSKDRP----YDYKADVWSLG-ITLIEMAEIEPPHH 236
Query: 369 DGSEASIIKNVRTGKLNFTAR--QWIAITDSAKSFVKKCLQVSTFNRCDVEEALHQVWV- 425
+ + ++ + + A+ +W + + K F+KKCL+ + R + L +V
Sbjct: 237 ELNPMRVLLKIAKSEPPTLAQPSRW---SSNFKDFLKKCLEKNVDARWTTSQLLQHPFVT 293
Query: 426 ---EKHTSQLERIYKKKVLQLSSDCIKIDENIDT 456
K +L K +V + D + DE +T
Sbjct: 294 VDSNKPIRELIAEAKAEVTEEVEDGKEEDEEEET 327
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.320 0.136 0.399
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,538,173
Number of Sequences: 60738
Number of extensions: 1275555
Number of successful extensions: 8565
Number of sequences better than 1.0e-05: 1415
Number of HSP's better than 0.0 without gapping: 42
Number of HSP's successfully gapped in prelim test: 1376
Number of HSP's that attempted gapping in prelim test: 5300
Number of HSP's gapped (non-prelim): 1599
length of query: 487
length of database: 30,389,216
effective HSP length: 110
effective length of query: 377
effective length of database: 23,708,036
effective search space: 8937929572
effective search space used: 8937929572
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)