ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI6331 check: MH U KOG0566 Intracellular trafficking, secretion, and vesicular transport Inositol-1,4,5-triphosphate 5-phosphatase (synaptojanin), INP51/INP52/INP53 family
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI6331 2203276 2206554 1093
(1093 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YOR109w [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (syn... 1214 0.0
YNL106c [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (syn... 1169 0.0
SPBC2G2.02 [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (... 712 0.0
YIL002c [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (syn... 468 e-131
SPBC577.13 [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (... 422 e-117
Hs4507335 [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (s... 386 e-106
7291368 [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (syn... 375 e-103
Hs14747866 [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (... 372 e-102
CE28239 [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (syn... 369 e-101
CE29050 [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (syn... 365 e-100
Hs22045277 [U] KOG0565 Inositol polyphosphate 5-phosphatase and ... 213 1e-54
7300754 [I] KOG1890 Phosphoinositide phosphatase SAC1 207 7e-53
YKL212w [I] KOG1889 Putative phosphoinositide phosphatase 207 9e-53
SPBC19F5.03 [I] KOG1889 Putative phosphoinositide phosphatase 203 1e-51
7290234 [U] KOG0565 Inositol polyphosphate 5-phosphatase and rel... 200 1e-50
Hs13325072 [U] KOG0565 Inositol polyphosphate 5-phosphatase and ... 196 1e-49
Hs13325070 [U] KOG0565 Inositol polyphosphate 5-phosphatase and ... 196 1e-49
CE20170 [I] KOG1890 Phosphoinositide phosphatase SAC1 191 7e-48
Hs7662338 [I] KOG1889 Putative phosphoinositide phosphatase 185 4e-46
CE09807 [I] KOG1889 Putative phosphoinositide phosphatase 185 4e-46
Hs7662414 [I] KOG1890 Phosphoinositide phosphatase SAC1 182 2e-45
At5g66020 [I] KOG1889 Putative phosphoinositide phosphatase 179 3e-44
At3g51830 [I] KOG1889 Putative phosphoinositide phosphatase 178 4e-44
7292047 [I] KOG1889 Putative phosphoinositide phosphatase 176 2e-43
At2g01900 [U] KOG0565 Inositol polyphosphate 5-phosphatase and r... 169 2e-41
CE17405 [U] KOG0565 Inositol polyphosphate 5-phosphatase and rel... 168 5e-41
SPAC9G1.10c [U] KOG0565 Inositol polyphosphate 5-phosphatase and... 162 3e-39
At3g51460 [I] KOG1889 Putative phosphoinositide phosphatase 161 6e-39
Hs9845291 [U] KOG0565 Inositol polyphosphate 5-phosphatase and r... 154 1e-36
At2g37440 [U] KOG0565 Inositol polyphosphate 5-phosphatase and r... 153 2e-36
7294594 [U] KOG0565 Inositol polyphosphate 5-phosphatase and rel... 147 1e-34
ECU08g1420 [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (... 145 3e-34
At1g47510 [U] KOG0565 Inositol polyphosphate 5-phosphatase and r... 144 6e-34
At2g32010 [U] KOG0565 Inositol polyphosphate 5-phosphatase and r... 144 8e-34
At5g04980 [U] KOG0565 Inositol polyphosphate 5-phosphatase and r... 140 8e-33
At1g05470 [U] KOG0565 Inositol polyphosphate 5-phosphatase and r... 140 1e-32
CE08566 [I] KOG1888 Putative phosphoinositide phosphatase 137 7e-32
At1g71710 [U] KOG0565 Inositol polyphosphate 5-phosphatase and r... 137 9e-32
7293245 [U] KOG0565 Inositol polyphosphate 5-phosphatase and rel... 137 1e-31
At2g43900 [U] KOG0565 Inositol polyphosphate 5-phosphatase and r... 135 3e-31
At5g65090 [U] KOG0565 Inositol polyphosphate 5-phosphatase and r... 134 6e-31
At3g63240 [U] KOG0565 Inositol polyphosphate 5-phosphatase and r... 134 6e-31
At1g05630 [U] KOG0565 Inositol polyphosphate 5-phosphatase and r... 134 8e-31
At2g31830 [U] KOG0565 Inositol polyphosphate 5-phosphatase and r... 132 2e-30
At4g18010 [U] KOG0565 Inositol polyphosphate 5-phosphatase and r... 130 1e-29
7302845 [U] KOG0565 Inositol polyphosphate 5-phosphatase and rel... 128 4e-29
7295697 [I] KOG1888 Putative phosphoinositide phosphatase 128 6e-29
YNL325c [I] KOG1888 Putative phosphoinositide phosphatase 125 3e-28
Hs5031799 [U] KOG0565 Inositol polyphosphate 5-phosphatase and r... 125 3e-28
At1g34120 [U] KOG0565 Inositol polyphosphate 5-phosphatase and r... 125 4e-28
Hs20537935 [U] KOG0565 Inositol polyphosphate 5-phosphatase and ... 124 8e-28
CE00123 [U] KOG0565 Inositol polyphosphate 5-phosphatase and rel... 124 8e-28
Hs4755142_1 [U] KOG0565 Inositol polyphosphate 5-phosphatase and... 124 1e-27
Hs7662034 [I] KOG1888 Putative phosphoinositide phosphatase 123 2e-27
ECU03g1160 [I] KOG1889 Putative phosphoinositide phosphatase 120 1e-26
At1g17340 [I] KOG1888 Putative phosphoinositide phosphatase 115 5e-25
Hs18765709 [U] KOG0565 Inositol polyphosphate 5-phosphatase and ... 114 8e-25
SPAC3C7.01c [I] KOG1889 Putative phosphoinositide phosphatase 110 1e-23
At3g43220 [I] KOG1888 Putative phosphoinositide phosphatase 108 4e-23
Hs22068673 [U] KOG0565 Inositol polyphosphate 5-phosphatase and ... 105 5e-22
Hs18765707 [U] KOG0565 Inositol polyphosphate 5-phosphatase and ... 99 4e-20
At5g20840 [I] KOG1888 Putative phosphoinositide phosphatase 96 2e-19
YOL065c [U] KOG0565 Inositol polyphosphate 5-phosphatase and rel... 88 8e-17
At1g22620 [I] KOG1888 Putative phosphoinositide phosphatase 87 2e-16
At1g65580 [U] KOG0565 Inositol polyphosphate 5-phosphatase and r... 85 5e-16
CE28690 [U] KOG0565 Inositol polyphosphate 5-phosphatase and rel... 71 1e-11
ECU10g1370 [U] KOG0565 Inositol polyphosphate 5-phosphatase and ... 67 2e-10
At3g59770 [I] KOG1888 Putative phosphoinositide phosphatase 64 1e-09
Hs22066536 [U] KOG0565 Inositol polyphosphate 5-phosphatase and ... 53 3e-06
>YOR109w [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (synaptojanin)
INP51/INP52/INP53 family
Length = 1107
Score = 1214 bits (3142), Expect = 0.0
Identities = 587/921 (63%), Positives = 730/921 (78%), Gaps = 3/921 (0%)
Query: 1 MQILVQQGPERVIALASESFALLLKYVPPKDKTHPVCTIEMVPKSYLKKQKFEKLSKLEI 60
M I V + PER +A+ S +AL+LK V K P+C IE++ K+ LKK F++L+ EI
Sbjct: 1 MIIFVSEEPERRLAIVSNLYALVLKPVGKKPSDKPLCAIELLQKNDLKKYGFKRLTSHEI 60
Query: 61 HGFIGLIELEGSIFIGTITGKSEVASPIPGETVNKIYGVDFFCLDSNRWDFVEFDSNGFP 120
G IGLIE+ G +F+G ITGKS+VA P PGETVNKI+ VDFFCL+ N WDF+E DS+G+P
Sbjct: 61 FGVIGLIEVNGLLFVGAITGKSKVAQPCPGETVNKIFAVDFFCLNDNSWDFIEIDSSGYP 120
Query: 121 IIPEEEYASSSNQQQQHPCHDLKKLLSNGSFYYSSDFDLTSLLQSRGLNQHSLSFDNYQE 180
++PE + +HPC++LKKLLSNGSFYYSSDFDLTS LQ RG QHSLS D Y+E
Sbjct: 121 VLPETASTEYQDALPKHPCYELKKLLSNGSFYYSSDFDLTSTLQHRGYGQHSLSTDTYEE 180
Query: 181 EYMWNSFLMQEIITFRNHLDDKAKQIMDDEGFLTTVIRGFAETFPSYIGRMPVNLTMISK 240
EYMWNSFLMQE+IT+R+HLD KQI+DDEGFLTTVIRGFAETF SY+ ++ V LT+ISK
Sbjct: 181 EYMWNSFLMQEMITYRDHLDTNLKQILDDEGFLTTVIRGFAETFVSYVKKLKVALTIISK 240
Query: 241 QSWKRAGTRFNVRGIDDEANVANFCETEFIMYSEEYCFAVTEIRGSVPVFWEQDTALINP 300
QSWKRAGTRFN RG+DDEANVANF ETEFIMYS +YC+A T+IRGS+PVFWEQ T+LINP
Sbjct: 241 QSWKRAGTRFNARGVDDEANVANFVETEFIMYSSQYCYAFTQIRGSIPVFWEQGTSLINP 300
Query: 301 KVTITRSVEATQSTFDEHFKRLIQKYGPVHVVNLLSTKSSEIELTRRYREHFERSKSLKL 360
+V ITRS EATQ FD+H + ++KYGPVHVVNLLSTKSSEIEL++RY+EH SK L
Sbjct: 301 RVQITRSFEATQPVFDKHIMKSVEKYGPVHVVNLLSTKSSEIELSKRYKEHLTHSKKLNF 360
Query: 361 NSEIFLTEFDFHKETKEEGFAAASKIMPTLERSILENGYFSYDVKEKKQLSEQNGVFRTN 420
N +IFLTEFDFHKET +EGF+ K++P + S+L +GY+SYDV+EKK +SEQ+G+FRTN
Sbjct: 361 NKDIFLTEFDFHKETSQEGFSGVRKLIPLILDSLLSSGYYSYDVREKKNISEQHGIFRTN 420
Query: 421 CLDCLDRTNLIQQFISRYTFILFLEDFQLIKPKLPLIEEYDWYQKHNNIWADHGDAVSQI 480
CLDCLDRTNL QQ IS F FLEDF+LI I++ D+ KHN +WADHGD +SQI
Sbjct: 421 CLDCLDRTNLAQQIISLAAFRTFLEDFRLISSN-SFIDDDDFVSKHNTLWADHGDQISQI 479
Query: 481 YTGTNALKSSFSRKGKMSFAGALSDATKSVSRMYINNFMDKNKQMNIDALLGRLPHQHSV 540
YTGTNALKSSFSRKGKMS AGALSDATKSVSR+YINNFMDK KQ NID LLGRLP+Q +V
Sbjct: 480 YTGTNALKSSFSRKGKMSLAGALSDATKSVSRIYINNFMDKEKQQNIDTLLGRLPYQKAV 539
Query: 541 ELFDPINDYVNEELRKQEAQFTTTSNIKILCGTFNVNGLTKSVDLSEWLYPIGKRYLPDI 600
+L+DP+N+YV+ +L+ +FT+TSNI +L G+FNVNG TK VDLS+WL+PIG+++ PDI
Sbjct: 540 QLYDPVNEYVSTKLQSMSDKFTSTSNINLLIGSFNVNGATKKVDLSKWLFPIGEKFKPDI 599
Query: 601 VVLGLQEVIELNASSILNVDTSKSQFWKDLVHSCLNKHEN-YIMLRAEQMSSLIILFFVK 659
VVLGLQEVIEL+A SILN D SKS FW++LV CLN++++ Y++LR EQM+SL+ILFFVK
Sbjct: 600 VVLGLQEVIELSAGSILNADYSKSSFWENLVGDCLNQYDDKYLLLRVEQMTSLLILFFVK 659
Query: 660 ADKVGNVKRVEGSSKKTGLGGMTGNKGAVAIRFDYGSTSFCFINAHLSAGVNNVEERRSD 719
ADK VK+VEG++KKTG GM GNKGAV+IRF+YG+TSFCF+N+HL+AG NVEERRSD
Sbjct: 660 ADKAKYVKQVEGATKKTGFRGMAGNKGAVSIRFEYGATSFCFVNSHLAAGATNVEERRSD 719
Query: 720 YESITKGISFSRSKRIDHHNSTFWLGDLNYRIELPNEKVRSILSLPDNADLDKLLEHDQL 779
YESI +GI+F+R+K I HH+S FWLGD+NYRI LPNE VR L + +DKLL DQL
Sbjct: 720 YESIVRGITFTRTKMIPHHDSIFWLGDMNYRINLPNEDVRRELLNQEEGYIDKLLHFDQL 779
Query: 780 TSEMASESVFKGFMEPSIQFRPTYKYDHGTDRYDTSEKARIPSWTDRILYKGENLQPMAY 839
T + S SVF+GF EP+++FRPTYKYD GT YD+SEK R PSWTDRI+YKGENL P++Y
Sbjct: 780 TLGINSGSVFEGFKEPTLKFRPTYKYDPGTGTYDSSEKERTPSWTDRIIYKGENLLPLSY 839
Query: 840 SDAKLNLSDHKPXXXXXXXXXXFIDEESKIQMTKKLYMDYKQSHPQDSGSINSALLDLEL 899
SDA + +SDH+P F+D++ ++ + K+L+ +YKQ HP++ GS+ S LL L+L
Sbjct: 840 SDAPIMISDHRPVYAAYRAKITFVDDKERLSLKKRLFTEYKQEHPEEPGSLISDLLSLDL 899
Query: 900 VDAKEEPKPVISTEMSLLDLD 920
D K S+E SLLD+D
Sbjct: 900 -DNKSTDGFKSSSESSLLDID 919
>YNL106c [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (synaptojanin)
INP51/INP52/INP53 family
Length = 1183
Score = 1169 bits (3024), Expect = 0.0
Identities = 571/949 (60%), Positives = 726/949 (76%), Gaps = 30/949 (3%)
Query: 1 MQILVQQGPERVIALASESFALLLKYVPPKDKTHPVCTIEMVPKSYLKKQKFEKLSKLEI 60
M+IL+ + R IA+ SE+ L+ + + K+ C +E+VPK+ L F +LS EI
Sbjct: 1 MKILLSKQQTRKIAIVSETHGLVFRPINSKNSRRSTCAVELVPKAELNGNGFRRLSNHEI 60
Query: 61 HGFIGLIELEGSIFIGTITGKSEVASPIPGETVNKIYGVDFFCLDSNRWDFVEFDSNGFP 120
+GFIGLIE+EG +FI TITGKS+VA PIP +TVNKIY VDFFCL++++WDF++ DS+G+P
Sbjct: 61 YGFIGLIEIEGLMFIATITGKSKVAQPIPNKTVNKIYAVDFFCLNNSKWDFMDIDSSGYP 120
Query: 121 IIPEE-EYASSS---------------------NQQQQ---HPCHDLKKLLSNGSFYYSS 155
I+ + ++A SS N Q+Q HPCH+L+KLLSNGSFYYS+
Sbjct: 121 IVTNDGDFAISSPPSISTHSSRSSLRSSSSRSLNAQEQAPKHPCHELRKLLSNGSFYYST 180
Query: 156 DFDLTSLLQSRGLNQHSLSFDNYQEEYMWNSFLMQEIITFRNHLDDKAKQIMDDEGFLTT 215
DFDLT LQ RG +HSLSFD++ E+MWNSFLM EIIT+R+ LD AK+++D GFLTT
Sbjct: 181 DFDLTCTLQKRGFTEHSLSFDDFDREFMWNSFLMDEIITYRDRLDVTAKELLDQRGFLTT 240
Query: 216 VIRGFAETFPSYIGRMPVNLTMISKQSWKRAGTRFNVRGIDDEANVANFCETEFIMYSEE 275
VIRGFAET SYI R+ V LT+IS+QSWKRAGTRFN RGIDD+ +VANF ETE IMYS +
Sbjct: 241 VIRGFAETIFSYINRLKVGLTIISRQSWKRAGTRFNARGIDDDGHVANFVETEMIMYSSQ 300
Query: 276 YCFAVTEIRGSVPVFWEQDTALINPKVTITRSVEATQSTFDEHFKRLIQKYGPVHVVNLL 335
YC+A T+IRGS+P+FWEQDT+LI+PK+ ITRSVEATQ TFDEHF RL +KYGPVH++NLL
Sbjct: 301 YCYAFTQIRGSLPIFWEQDTSLISPKIQITRSVEATQPTFDEHFIRLFKKYGPVHIINLL 360
Query: 336 STKSSEIELTRRYREHFERSKSLKLNSEIFLTEFDFHKETKEEGFAAASKIMPTLERSIL 395
STKSSEI+L+RRY+E + S+ +K+ ++FLT FDFH+ET ++GFAAAS+I+P + +IL
Sbjct: 361 STKSSEIQLSRRYKEQLKNSEKMKIGRDVFLTSFDFHRETSQDGFAAASRIIPKIRNTIL 420
Query: 396 ENGYFSYDVKEKKQLSEQNGVFRTNCLDCLDRTNLIQQFISRYTFILFLEDFQLIKPKLP 455
+ GYFSYDVKE + +SEQ+GVFRTNCLDCLDRTNLIQQ IS F LFLEDF+L+KP
Sbjct: 421 DAGYFSYDVKEGRLISEQDGVFRTNCLDCLDRTNLIQQTISLAVFKLFLEDFRLVKPS-S 479
Query: 456 LIEEYDWYQKHNNIWADHGDAVSQIYTGTNALKSSFSRKGKMSFAGALSDATKSVSRMYI 515
I++ ++ QK N +WAD+GD +SQIYTGTNALKSS+SRKGKMSF+GALSDATKSVSRMYI
Sbjct: 480 FIDDNEFVQKVNALWADNGDQISQIYTGTNALKSSYSRKGKMSFSGALSDATKSVSRMYI 539
Query: 516 NNFMDKNKQMNIDALLGRLPHQHSVELFDPINDYVNEELRKQEAQFTTTSNIKILCGTFN 575
NNF+DK KQ NID LLG+LPHQ VEL+DPI +YVNE L + E +FTT SNI + GTFN
Sbjct: 540 NNFVDKGKQQNIDTLLGKLPHQQVVELYDPICEYVNERLLESEEKFTTHSNINLFVGTFN 599
Query: 576 VNGLTKSVDLSEWLYPIGKRYLPDIVVLGLQEVIELNASSILNVDTSKSQFWKDLVHSCL 635
VNG ++ DLS+WL+PIG ++ PD+VVLGLQEVIEL A SILN D +KS FW+ +V CL
Sbjct: 600 VNGNSRRADLSKWLFPIGDKFKPDVVVLGLQEVIELTAGSILNADYTKSSFWETMVTDCL 659
Query: 636 NKH-ENYIMLRAEQMSSLIILFFVKADKVGNVKRVEGSSKKTGLGGMTGNKGAVAIRFDY 694
N++ E Y++LR EQMSSL+ILFF ++D+ N+K V GS+KKTG GG+TGNKGAVAIRFDY
Sbjct: 660 NQYEEKYLLLRVEQMSSLLILFFARSDRAYNIKEVGGSTKKTGFGGITGNKGAVAIRFDY 719
Query: 695 GSTSFCFINAHLSAGVNNVEERRSDYESITKGISFSRSKRIDHHNSTFWLGDLNYRIELP 754
G+TSFCF+N HLSAG +N++ERR+DY +I + I+F RSK I HH+S FWLGDLNYRI L
Sbjct: 720 GATSFCFVNTHLSAGASNIDERRNDYNNIYRNITFPRSKTIPHHDSLFWLGDLNYRITLT 779
Query: 755 NEKVRSILSLPDNADLDKLLEHDQLTSEMASESVFKGFMEPSIQFRPTYKYDHGTDRYDT 814
N++VR L + +D+LL++DQLT E+ VF+GF EP++QFRPTYKYD+GTD YDT
Sbjct: 780 NDEVRRELRAQKDGYIDRLLQYDQLTQEINEGVVFQGFKEPTLQFRPTYKYDYGTDNYDT 839
Query: 815 SEKARIPSWTDRILYKGENLQPMAYSDAKLNLSDHKPXXXXXXXXXXFIDEESKIQMTKK 874
SEKAR PSWTDRI+YKGENL P+AYSDA L +SDHKP F+DE+ K+ + +K
Sbjct: 840 SEKARTPSWTDRIIYKGENLHPLAYSDAPLKISDHKPVYAAYRANVKFVDEKEKLNLVEK 899
Query: 875 LYMDYKQSHPQDSGSINSALLDLELVDAKEE---PKPVISTEMSLLDLD 920
LY +YK +HP+ + L + KE V S + L+DLD
Sbjct: 900 LYAEYKNTHPEALTTGPDELSHARMEKQKESIPLDATVQSAGIKLIDLD 948
>SPBC2G2.02 [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (synaptojanin)
INP51/INP52/INP53 family
Length = 1076
Score = 712 bits (1838), Expect = 0.0
Identities = 391/907 (43%), Positives = 554/907 (60%), Gaps = 31/907 (3%)
Query: 1 MQILVQQGPERVIALASESFALLLKYVPPKDKTHPVCTIEMVPKSYLKKQKFEKLSKLEI 60
MQ L+++ P R +AL ++ AL+ VP + VC E S + F K+S I
Sbjct: 1 MQCLLREKP-RSLALVNKDHALMFHSVPQNKNSLSVCVAEFTALSEKPLEGFRKISSHRI 59
Query: 61 HGFIGLIELEGSIFIGTITGKSEVASPIPGETVNKIYGVDFFCLDSNRWDFVEFDSNGFP 120
+G +GLIELEGS F+ I+G SEVA E V +I V F+ ++ + WD + N P
Sbjct: 60 YGTLGLIELEGSNFLCVISGASEVARVRDKERVFRIMEVCFYSVNRSNWDHIR-QENYSP 118
Query: 121 IIPE----EEYASSSNQQQQHPCHDLKKLLSNGSFYYSSDFDLTSLLQSR-GLNQHSLSF 175
IP+ + S + P L+KLL+NGSFY+S DFD+T+ LQ R +
Sbjct: 119 DIPDGYDTDTQGYDSYKYAAEPFSSLRKLLTNGSFYFSLDFDITTRLQLRTSQTMTEPQY 178
Query: 176 DNYQEEYMWNSFLMQEIITFRNHLDDKAKQIMDDEGFLTTVIRGFAETFPSYIGRMPVNL 235
D+ ++MWN F+++++I FR+HL+ K +D F T IRGFA T +G + L
Sbjct: 179 DSMHTQFMWNEFMLRQLIKFRSHLNGDEKSALDGCRFFTCAIRGFASTEQFKLGIQTIRL 238
Query: 236 TMISKQSWKRAGTRFNVRGIDDEANVANFCETEFIMYSEEYCFAVTEIRGSVPVFWEQD- 294
++IS+ S RAGTRF RG+DD+ NVANF ETE I+ S +YC + ++RGS+P+FWEQ+
Sbjct: 239 SLISRLSSLRAGTRFLSRGVDDDGNVANFVETETILDSSKYCVSYCQVRGSIPIFWEQEG 298
Query: 295 TALINPKVTITRSVEATQSTFDEHFKRLIQKYGPVHVVNLLSTKSSEIELTRRYREHFER 354
+ K+ ITRS+EAT++ F++HF LI++YGPVH++NLL T S E L+ R R+H +
Sbjct: 299 VQMFGQKIDITRSLEATRAAFEKHFTSLIEEYGPVHIINLLGTGSGERSLSERLRQHIQL 358
Query: 355 SKSLKLNSEIFLTEFDFHKETKEEGFAAASKIMPTLERSILENGYFSYDVKEKKQLSEQN 414
S L I LTEFD+H + + F A+KI P + G++ ++ E + + Q+
Sbjct: 359 SPEKDL---IHLTEFDYHSQIRS--FEDANKIRPMIYSDAETFGFY-FENNEGQSIVVQD 412
Query: 415 GVFRTNCLDCLDRTNLIQQFISRYTFILFLEDFQLIKPKLPLIEEYDWYQKHNNIWADHG 474
GVFRTNCLDCLDRTN+IQ +SR +FLE + + YD++Q H+ IWA++G
Sbjct: 413 GVFRTNCLDCLDRTNVIQNLVSR----VFLEQVMIYTRQNA---GYDFWQVHSTIWANNG 465
Query: 475 DAVSQIYTGTNALKSSFSRKGKMSFAGALSDATKSVSRMYINNFMDKNKQMNIDALLGRL 534
DA+++IYTGT ALKSSF+RKGK+S AGAL+D +KSV RMYINNF DK +Q ID LLGRL
Sbjct: 466 DALARIYTGTGALKSSFTRKGKLSIAGALNDLSKSVGRMYINNFQDKGRQETIDLLLGRL 525
Query: 535 PHQHSVELFDPINDYVNEELRKQEAQFTTTSNIKILCGTFNVNGLTKSVDLSEWLYPIGK 594
QH V L+DPI++YVN ELRK+E +F+ N+KI ++N+NG + + L WL+P
Sbjct: 526 IDQHPVILYDPIHEYVNHELRKRENEFSEHKNVKIFVASYNLNGCSATTKLENWLFP-EN 584
Query: 595 RYLPDIVVLGLQEVIELNASSILNVDTSKSQFWKDLVHSCLN----KHENYIMLRAEQMS 650
L DI V+G QE+++L +++ D +K + W+ V LN Y+ LR+ Q+
Sbjct: 585 TPLADIYVVGFQEIVQLTPQQVISADPAKRREWESCVKRLLNGKCTSGPGYVQLRSGQLV 644
Query: 651 SLIILFFVKADKVGNVKRVEGSSKKTGLGGMTGNKGAVAIRFDYGSTSFCFINAHLSAGV 710
++ F K + ++K VEG+ KKTGLGG++GNKGAVAIRFDY T CFI +HL+AG
Sbjct: 645 GTALMIFCKESCLPSIKNVEGTVKKTGLGGVSGNKGAVAIRFDYEDTGLCFITSHLAAGY 704
Query: 711 NNVEERRSDYESITKGISFSRSKRIDHHNSTFWLGDLNYRIELPNEKVRSILSLPDNADL 770
N +ER DY +I G+ F R + I +H+ W GD NYRI L E+V ++ L
Sbjct: 705 TNYDERDHDYRTIASGLRFRRGRSIFNHDYVVWFGDFNYRISLTYEEVVPCIA---QGKL 761
Query: 771 DKLLEHDQLTSEMASESVFKGFMEPSIQFRPTYKYDHGTDRYDTSEKARIPSWTDRILYK 830
L E+DQL +M + VF F E I F PTYK+D GTD YDTS+K R+P+WTDRILY+
Sbjct: 762 SYLFEYDQLNKQMLTGKVFPFFSELPITFPPTYKFDIGTDIYDTSDKHRVPAWTDRILYR 821
Query: 831 GENLQPMAYSDAKLNLSDHKPXXXXXXXXXXFIDEESKIQMTKKLYMDYKQSHPQDSGSI 890
GE L P +Y L SDH+P +D E K + ++LY KQ +D+
Sbjct: 822 GE-LVPHSYQSVPLYYSDHRPIYATYEANIVKVDREKKKILFEELYNQRKQ-EVRDASQT 879
Query: 891 NSALLDL 897
+ L+D+
Sbjct: 880 SYTLIDI 886
>YIL002c [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (synaptojanin)
INP51/INP52/INP53 family
Length = 946
Score = 468 bits (1205), Expect = e-131
Identities = 276/864 (31%), Positives = 459/864 (52%), Gaps = 88/864 (10%)
Query: 35 PVCTIEMVPKSYLKKQK-FEKLSKLEIHGFIGLIELEGSIFIGTITGKSEVASPI----- 88
P TI+ P + L + ++ +G +GL+ L G I++ I+G V P
Sbjct: 43 PSVTIKSYPDTDLSSDSNYLEVKSCIFNGLLGLVCLNGDIYVAVISGVQNVGFPRWKLID 102
Query: 89 ----PGETVNKIYGVDFFCLDSNRWDFVEFDSNGFPIIPEEEYASSSNQQQQHPCHDLKK 144
P E++ K+ VDF+ L+++ +D+ ++ E + +HPC LKK
Sbjct: 103 HQVRPSESIYKVLDVDFYSLENDVFDY---------LLCERSEQNYDKLIHEHPCGPLKK 153
Query: 145 LLSNGSFYYSSDFDLTSLLQSRGLNQHSLSF--DNYQEEYMWNSFLMQEIITFRNHLDDK 202
L S+G+FYYS DFD+++++++ GL+ H+L + DN ++WN+ L E+I +R+ + ++
Sbjct: 154 LFSDGTFYYSRDFDISNIVKNHGLS-HNLEYTVDNQDLSFIWNANLASEVINWRSKISNE 212
Query: 203 AKQIMDDEGFLTTVIRGFAETFPSYIGRMPVNLTMISKQSWKRAGTRFNVRGIDDEANVA 262
KQ+ + GFLT VIRG+ +T G ++T+IS+ S + + GI ++ V+
Sbjct: 213 EKQLFANAGFLTFVIRGYCKTALIEDGPNTASITIISRISTESKQDTLELEGISEDGRVS 272
Query: 263 NFCETEFIMYSEEYCFAVTEIRGSVPVFWE--QDTALINPKVTITRSVEATQSTFDEHFK 320
F ETE ++ +E++ F+ T++ GS+P+FWE + L K+ +T+ Q FD HF
Sbjct: 273 LFVETEIVVTTEKFIFSYTQVNGSIPLFWESVESQLLYGKKIKVTKDSIEAQGAFDRHFD 332
Query: 321 RLIQKYGPVHVVNLLSTKS-SEIELTRRYREHFERSKSLKLNSEIFLTEFDFHKETKEEG 379
L KYG V +VN++ KS S+ +L Y++ E SK +K+ + E+ TK
Sbjct: 333 NLTSKYGVVSIVNIIKPKSESQEKLALTYKDCAE-SKGIKITN----IEYSSSVLTK--- 384
Query: 380 FAAASKIMPTLERSILENGYFSYDVKEKKQLSEQNGVFRTNCLDCLDRTNLIQQFISRYT 439
+ K++ L++ I E G F+YD+ ++Q GV R + D +++ N +++ +S+
Sbjct: 385 --SPHKLLYLLKQDIYEFGAFAYDISRGIYFAKQTGVLRISAFDSIEKPNTVERLVSKEV 442
Query: 440 FILFLEDFQLIKPKLPLIEEYDWYQKHNNIWADHGDAVSQIYTGTNALKSSFSRKGKMSF 499
L + + + P ++ +D N W D T T K+S GK
Sbjct: 443 LELTTNEIDVFELTSPFLDAHDKLWSENYYWLDR--------TYTKHTKNS----GKY-- 488
Query: 500 AGALSDATKSVSRMYINNFMDKNKQMNIDALLGRLPHQHSVELFDPINDYVNEELRKQEA 559
TK S+++ + V L+DP++ Y+++ L++ +
Sbjct: 489 -------TKVYSKLFGSR----------------------VRLYDPLHIYISQYLKQLRS 519
Query: 560 QFTTTSNIKILCGTFNVNGLTKSVDLSEWLYPIG---KRYLPDIVVLGLQEVIELNASSI 616
++T +I I GTFN++G D+ +W++P + + D+ V+GL+EV+EL +
Sbjct: 520 KYTFEKDISIFAGTFNISGKIPKDDIKDWIFPKSMSKEDEMADLYVIGLEEVVELTPGHM 579
Query: 617 LNVDTSKSQFWKDLVHSCLN---KHENYIMLRAEQMSSLIILFFVKADKVGNVKRVEGSS 673
L D QFW+ + + LN + + YI L + Q+ +++L F+ + VK +EG
Sbjct: 580 LATDPYVRQFWEKKILTLLNGPGRKKKYIRLWSTQLGGILLLLFMNETEYSKVKHIEGDV 639
Query: 674 KKTGLGGMTGNKGAVAIRFDYGSTSFCFINAHLSAGVNNVEERRSDYESITKGISFSRSK 733
KKTG GGM NKGAVA+ F Y +T FC + +HL+AG+ NVE+R +DY++I K I FS+
Sbjct: 640 KKTGFGGMASNKGAVAVSFKYSATRFCVLVSHLAAGLENVEQRHNDYKTIAKSIRFSKGL 699
Query: 734 RIDHHNSTFWLGDLNYRIELPNEKVRSILSLPDNADLDKLLEHDQLTSEMASESVFKGFM 793
RI H++ W+GD NYRI + NE VR + + A L E DQL +M + F F
Sbjct: 700 RIKDHDAIIWMGDFNYRILMSNEDVRRKIVSKEYA---SLFEKDQLNQQMIAGESFPYFH 756
Query: 794 EPSIQFRPTYKYDHGTDRYDTSEKARIPSWTDRILYKGENLQPMAYSDAK-LNLSDHKPX 852
E +I F PTYK+D GT YDTSEK RIP+WTDRIL +GE L+ + Y + + SDH+P
Sbjct: 757 EMAIDFPPTYKFDPGTKNYDTSEKMRIPAWTDRILSRGEVLEQLEYKCCEDILFSDHRPV 816
Query: 853 XXXXXXXXXFIDEESKIQMTKKLY 876
+DE+ K + ++Y
Sbjct: 817 YAIFRARVTVVDEQKKTTLGTQIY 840
>SPBC577.13 [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (synaptojanin)
INP51/INP52/INP53 family
Length = 889
Score = 422 bits (1084), Expect = e-117
Identities = 283/889 (31%), Positives = 460/889 (50%), Gaps = 91/889 (10%)
Query: 10 ERVIALASESFALLLKYVPPKDKTHPVCTIEMVPKSYLKKQKFEKLSKLE-------IHG 62
ER +A +E +A +++ KD C I + + ++FEK+ + E I G
Sbjct: 9 ERSVAFITEKYAAIIQKPSVKDSD---CIITF---TCISLEEFEKIKEYELLFGGEKILG 62
Query: 63 FIGLI-----ELEGSIFIGTITGKSEVASPIPG-ETVNKIYGVDFFCLDSNRWD---FVE 113
+GL +++ +F+ + K+++ I + ++K+ V F LD WD F
Sbjct: 63 TLGLFNYVCEDMKEGVFL-CVARKAKLVLRIGNRDPISKLENVSFISLDQELWDEELFEP 121
Query: 114 FDSNGFPI-----------------IPEEEYASS-SNQQQQHPCHDLKKL---LSNGSFY 152
N P + EY+S S+ + +P H L +L L++GSFY
Sbjct: 122 MPRNSSPSSTFSTSTSDLNNIEKDNLVNSEYSSKYSSTTRIYPYHSLSQLTDLLTDGSFY 181
Query: 153 YSSDFDLTSLLQSRGLNQHSLSFDNYQEEYMWNSFLMQEIITFRNHLDDKAKQIMDDEGF 212
S++ S QS ++ Y WN FL+ E+ NH + A +
Sbjct: 182 VSTNISCFSRFQSEQPY-------GPKDIYCWNRFLITEL---DNHFSE-AHILEKFPNL 230
Query: 213 LTTVIRGFAETFPSYIGRMPVNLTMISKQSWKRAGTRFNVRGIDDEANVANFCETEFIMY 272
L RG+ E +I M ++++ISK S + + GIDD + + F ETEFI+
Sbjct: 231 LLHCFRGYVERM--FIDSM--SMSIISKVSSYGSRQTYPPSGIDDSSYCSMFVETEFIVE 286
Query: 273 SEEYCFAVTEIRGSVPVFWEQD-TALINPKVTITRSVEATQSTFDEHFKRLIQKYGPVHV 331
+ F+ ++RG+VP FWE+ ++ P ++ RS +A+QS F+ HF +L + YG ++V
Sbjct: 287 IAQTVFSFVQVRGTVPCFWEEQFSSWYGPSISFLRSSQASQSLFNFHFSKLYKAYGDIYV 346
Query: 332 VNLLSTKSSEIELTRRYREHFERSKSLKLNSEIFLTEFDFHKETKEEGFAAASKIMPTLE 391
++LL TK E L Y+ H + L + +F F + A I P LE
Sbjct: 347 IDLLQTKGFEASLYEAYKHHL-----MLLPFPAVVKKFHFTPDP------ARPDIDPRLE 395
Query: 392 RSILEN----GYFSYDVKEKKQLSEQNGVFRTNCLDCLDRTNLIQQFISRYTFILFLEDF 447
+ ++ GY ++ S Q GVFR N LDCL RTN+IQ ISR L L+D
Sbjct: 396 TDLADDLKEMGYTQKSIENDMLESFQKGVFRINDLDCLGRTNVIQYQISR----LVLKDI 451
Query: 448 QLIKPKLPLIEEYDWYQKHNNIWADHGDAVSQIYTGTNALKSSFSRKGKMSFAGALSDAT 507
L + ++ + ++W+++GDA++++ TG ++ SS +R+G+ S AG+LSD +
Sbjct: 452 FF---NLQIGVTFNILEYLRHLWSNNGDAIAKLITGVGSIGSSATRRGRKSIAGSLSDIS 508
Query: 508 KSVSRMYINNFMDKNKQMNIDALLGRLPHQHSVELFDPINDYVNEELRKQEAQFTTTSNI 567
KS RMY+ + D Q I LLG P+Q V + + ++ Y+ LR++ +++ +
Sbjct: 509 KSFGRMYVGRYPDVESQNAILLLLGCFPNQSPVLISESVSSYIQGVLRQRRSEYRVERDF 568
Query: 568 KILCGTFNVNGLTKSVD-LSEWLYPIGKRYLP-DIVVLGLQEVIELNASSILNVDTSKSQ 625
I TFN NG S D L P G+R D+ V+ +QE+I LN S +++ K +
Sbjct: 569 SIFSSTFNANGKVPSTDEFKRLLLPFGERTSAYDLYVVAVQEIITLNMSHLVSSSNQKLR 628
Query: 626 FWKDLVHSCLNKHEN---YIMLRAEQMSSLIILFFVKADKVGNVKRVEGSSKKTGLGGMT 682
W++ + LN ++ Y+++ + QM+ + + F++ D V +V +++KTG GG +
Sbjct: 629 IWEEKILMILNSRDSNNKYMLISSIQMAGVFLGVFIRKDDHLVVSKVTKTTRKTGFGGFS 688
Query: 683 GNKGAVAIRFDYGSTSFCFINAHLSAGVNNVEERRSDYESITKGISFSRSKRIDHHNSTF 742
NKGAVAI + + FCF+++H + VNN+ ER +Y SI+ + F +I H +
Sbjct: 689 ANKGAVAIEMNVCDSDFCFVSSHFAPKVNNISERNMEYTSISDNLVFPSGMKIYDHTNIL 748
Query: 743 WLGDLNYRIELPNEKVRSILSLPDNADLDKLLEHDQLTSEMASESVFKGFMEPSIQFRPT 802
W+GD NYRI+ NE+VR ++ L DLDKL +DQL +EM +VF G +EP + F PT
Sbjct: 749 WMGDFNYRIDSDNEEVRKLVELD---DLDKLASYDQLCTEMKKGTVFHGLVEPQLTFLPT 805
Query: 803 YKYDHGTDRYDTSEKARIPSWTDRILYKGENLQPMAYSDAKLNLSDHKP 851
YK+D+GT+ YDTS+K R+PSWTDRIL ++ Y + SDH+P
Sbjct: 806 YKFDNGTNDYDTSDKQRVPSWTDRIL-ATKSFTRNCYKSCDIRCSDHRP 853
>Hs4507335 [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (synaptojanin)
INP51/INP52/INP53 family
Length = 1575
Score = 386 bits (991), Expect = e-106
Identities = 239/755 (31%), Positives = 392/755 (51%), Gaps = 74/755 (9%)
Query: 115 DSNGFPIIPEEEYASSSNQQQQHPCHDLKKLLSNGSFYYSSDFDLTSLLQSRGLNQH-SL 173
+S F + E + + + +++K+L++G+FY++ + + + LN H S+
Sbjct: 92 ESEVFRVTSTEFISLRIDSSDEDRISEVRKVLNSGNFYFA--WSASGISLDLSLNAHRSM 149
Query: 174 SFDNYQEEYMWNSFLMQEIITFRNHLDDKAKQIMDDEGFLTTVIRGFAETFPSYIGRMPV 233
+ WN L + + + DD +L ++ G E Y
Sbjct: 150 QEQTTDNRFFWNQSLHLHLKHYGVNCDD----------WLLRLMCGGVEIRTIYAAHKQA 199
Query: 234 NLTMISKQSWKRAGTRFNVRGIDDEANVANFCETEFIMYSEEYCFAVTEIRGSVPVFWEQ 293
+IS+ S +RAGTRFNVRG +D+ +VANF ETE ++Y ++ + +IRGSVP+FWEQ
Sbjct: 200 KACLISRLSCERAGTRFNVRGTNDDGHVANFVETEQVVYLDDSVSSFIQIRGSVPLFWEQ 259
Query: 294 DTALINP-KVTITRSVEATQSTFDEHFKRLIQKYGPVHVVNLLSTKSSEIELTRRYREHF 352
+ +V ++R EA FD HF+ L YG +VNLL +K E L++ ++ H
Sbjct: 260 PGLQVGSHRVRMSRGFEANAPAFDRHFRTLKNLYGRQIIVNLLGSKEGEHMLSKAFQSHL 319
Query: 353 ERSKSLKLNSEIFLTEFDFHKETKEEGFAAASKIMPTLERSILENGYFSYDVKEKKQLSE 412
+ S+ ++I + FD+H+ K ++ + L+ G+F ++ E ++
Sbjct: 320 KASEHA---ADIQMVNFDYHQMVKGGKAEKLHSVLKPQVQKFLDYGFFYFNGSEVQRC-- 374
Query: 413 QNGVFRTNCLDCLDRTNLIQQFISRYTFILFLEDFQLIKPKLPLIEEYDWYQKHNNIWAD 472
Q+G RTNCLDCLDRTN +Q F+ LE L + K L+ + + ++W+
Sbjct: 375 QSGTVRTNCLDCLDRTNSVQAFLGLEMLAKQLEALGLAE-KPQLVTRFQ--EVFRSMWSV 431
Query: 473 HGDAVSQIYTGTNALKSSFSRKGKMSFAGALSDATKSVSRMYINNFMDKNKQMNIDALLG 532
+GD++S+IY GT AL+ L D +SV+R NNF D +KQ ID LL
Sbjct: 432 NGDSISKIYAGTGALEGK----------AKLKDGARSVTRTIQNNFFDSSKQEAIDVLL- 480
Query: 533 RLPHQHSVELFDPINDYVNE---ELRKQEAQFTTTSNIKILC----------------GT 573
L + + +L D + + +Q Q ++ +K +C GT
Sbjct: 481 -LGNTLNSDLADKARALLTTGSLRVSEQTLQSASSKVLKSMCENFYKYSKPKKIRVCVGT 539
Query: 574 FNVNG-------LTKSVDLSEWLYPI----------GKRYLP-DIVVLGLQEVIELNASS 615
+NVNG K+ L++WL KR P DI +G +E++ELNA +
Sbjct: 540 WNVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEFQDKRSKPTDIFAIGFEEMVELNAGN 599
Query: 616 ILNVDTSKSQFWKDLVHSCLNKHENYIMLRAEQMSSLIILFFVKADKVGNVKRVEGSSKK 675
I++ T+ + W + +++ Y++L +EQ+ + + F++ ++ V + K
Sbjct: 600 IVSASTTNQKLWAVELQKTISRDNKYVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDTVK 659
Query: 676 TGLGGMTGNKGAVAIRFDYGSTSFCFINAHLSAGVNNVEERRSDYESITKGISFSRSKRI 735
TG+GG TGNKGAVAIR + +TS CF+ +H +AG + V+ER D+ I + +SF + +
Sbjct: 660 TGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAAGQSQVKERNEDFIEIARKLSFPMGRML 719
Query: 736 DHHNSTFWLGDLNYRIELPNEKVRSILSLPDNADLDKLLEHDQLTSEMASESVFKGFMEP 795
H+ FW GD NYRI+LPNE+V+ ++ + D L+ DQL ++ + VF+GF+E
Sbjct: 720 FSHDYVFWCGDFNYRIDLPNEEVKELIR---QQNWDSLIAGDQLINQKNAGQVFRGFLEG 776
Query: 796 SIQFRPTYKYDHGTDRYDTSEKARIPSWTDRILYK 830
+ F PTYKYD +D YDTSEK R P+WTDR+L++
Sbjct: 777 KVTFAPTYKYDLFSDDYDTSEKCRTPAWTDRVLWR 811
>7291368 [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (synaptojanin)
INP51/INP52/INP53 family
Length = 1218
Score = 375 bits (963), Expect = e-103
Identities = 249/805 (30%), Positives = 396/805 (48%), Gaps = 107/805 (13%)
Query: 141 DLKKLLSNGSFYY-------------SSDFDLTSLLQSRGLNQHSLSFDNYQEEYMWNSF 187
+++KLL++G+FY+ S FD+T Q R Q + DN + WN
Sbjct: 119 EVRKLLNSGTFYFAHTNASASASGASSYRFDITLCAQRRQQTQET---DN---RFFWNRM 172
Query: 188 LMQEIITFRNHLDDKAKQIMDDEGFLTTVIRGFAETFPSYIGRMPVNLTMISKQSWKRAG 247
+ ++ F +D + +L + G E YIG +IS+ S +RAG
Sbjct: 173 MHIHLMRFG----------IDCQSWLLQAMCGSVEVRTVYIGAKQARAAIISRLSCERAG 222
Query: 248 TRFNVRGIDDEANVANFCETEFIMYSEEYCFAVTEIRGSVPVFWEQDTALINP-KVTITR 306
TRFNVRG +DE VANF ETE ++Y + + + RGSVP+FWEQ + KV ++R
Sbjct: 223 TRFNVRGTNDEGYVANFVETEQVIYVDGDVTSYVQTRGSVPLFWEQPGVQVGSHKVKLSR 282
Query: 307 SVEATQSTFDEHFKRLIQKYGPVHVVNLLST-----KSSEIELTRRYREHFERSKSLKLN 361
E + + FD H + Q+YG VVNLL + K E L+ ++ H + +
Sbjct: 283 GFETSAAAFDRHMSMMRQRYGYQTVVNLLGSSLVGSKEGEAMLSNEFQRHH----GMSAH 338
Query: 362 SEIFLTEFDFHKETKEEGFAAASKIMPTLERSILENGYFSYDVKEKKQLSEQNGVFRTNC 421
++ FD+H+E + F+A +K+ + G F + L EQ GV RTNC
Sbjct: 339 KDVPHVVFDYHQECRGGNFSALAKLKERIVACGANYGVFH--ASNGQVLREQFGVVRTNC 396
Query: 422 LDCLDRTNLIQQFISRYTFILFLEDFQLIKPKLPLIEEYDWYQKHNNIWADHGDAVSQIY 481
LDCLDRTN +Q ++ T + LE ++ K I ++ + +W ++G+ VS+IY
Sbjct: 397 LDCLDRTNCVQTYLGLDTLGIQLEALKM-GGKQQNISRFE--EIFRQMWINNGNEVSKIY 453
Query: 482 TGTNALKSSFSRKGKMSFAGALSDATKSVSRMYINNFMDKNKQMNIDALLGRLPHQHSVE 541
GT A++ L D +S +R NN +D +KQ ID LL + S E
Sbjct: 454 AGTGAIQGG----------SKLMDGARSAARTIQNNLLDNSKQEAIDVLL--VGSTLSSE 501
Query: 542 LFD------PIN-----DYVNEELRKQEAQFTTTSNIKILCGTFNVNG------LTKSVD 584
L D P N V EL K+ ++ ++ GT+NVNG +
Sbjct: 502 LADRARILLPSNMLHAPTTVLRELCKRYTEYVRPRMARVAVGTYNVNGGKHFRSIVFKDS 561
Query: 585 LSEWLYPI-----------------GKRYLPDIVVLGLQEVIELNASSILNVDTSKSQFW 627
L++WL + DI +G +E+++LNAS+I+ T ++ W
Sbjct: 562 LADWLLDCHALARSKALVDVNNPSENVDHPVDIYAIGFEEIVDLNASNIMAASTDNAKLW 621
Query: 628 KDLVHSCLNKHENYIMLRAEQMSSLIILFFVKADKVGNVKRVEGSSKKTGLGGMTGNKGA 687
+ + +++ +Y++L +Q+ + + +++ + +++ V KTGLGG TGNKGA
Sbjct: 622 AEELQKTISRDNDYVLLTYQQLVGVCLYIYIRPEHAPHIRDVAIDCVKTGLGGATGNKGA 681
Query: 688 VAIRFDYGSTSFCFINAHLSAGVNNVEERRSDYESITKGISFSRSKRIDHHNSTFWLGDL 747
AIRF TS CF+ AH +AG + V ER +DY IT+ ++F + + H+ FW GD
Sbjct: 682 CAIRFVLHGTSMCFVCAHFAAGQSQVAERNADYAEITRKLAFPMGRTLKSHDWVFWCGDF 741
Query: 748 NYRIELPNEKVRSILSLPDNADLDKLLEHDQLTSEMASESVFKGFMEPSIQFRPTYKYDH 807
NYRI++ ++++ + N DL +LE DQL E + +VF F+E I F PTYKYD
Sbjct: 742 NYRIDMEKDELKECVR---NGDLSTVLEFDQLRKEQEAGNVFGEFLEGEITFDPTYKYDL 798
Query: 808 GTDRYDTSEKARIPSWTDRILYKGENL--------------QPMAYSDAKLNLSDHKPXX 853
+D YDTSEK R P+WTDR+L++ + + Y ++L SDH+P
Sbjct: 799 FSDDYDTSEKQRAPAWTDRVLWRRRKALAEGDFAASAWNPGKLIHYGRSELKQSDHRPVI 858
Query: 854 XXXXXXXXFIDEESKIQMTKKLYMD 878
ID++ + + +++ D
Sbjct: 859 AIIDAEIMEIDQQRRRAVFEQVIRD 883
>Hs14747866 [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (synaptojanin)
INP51/INP52/INP53 family
Length = 1496
Score = 372 bits (956), Expect = e-102
Identities = 270/854 (31%), Positives = 424/854 (49%), Gaps = 109/854 (12%)
Query: 36 VCTIEMVPKSYLKKQKFEKLSKLEIHGFIGLIELEGS----IFIGTITGKSEVASPIPGE 91
V T+ K +K Q + KL+ + +G +G + L+ F+ +TG + V IP
Sbjct: 39 VATLAPEEKEVIKGQ-YGKLT--DAYGCLGELRLKSGGTSLSFLVLVTGCTSVGR-IPDA 94
Query: 92 TVNKIYGVDFFCLDSNRWDFVEFDSNGFPIIPEEEYASSSNQQQQHPCHDLKKLLSNGSF 151
+ KI DF+ L EEE + LKK+LS+G F
Sbjct: 95 EIYKITATDFYPLQEEA--------------KEEERLIA-----------LKKILSSGVF 129
Query: 152 YYS-----SDFDLTSLLQSRGLNQHSLSFDNYQEEYMWNSFLMQEIITFRNHLDDKAKQI 206
Y+S S FDLT Q +G + + + WN L H+ + Q+
Sbjct: 130 YFSWPNDGSRFDLTVRTQKQGDDS-----SEWGNSFFWNQLL---------HVPLRQHQV 175
Query: 207 MDDEGFLTTVIRGFAETFPSYIGRMPVNLTMISKQSWKRAGTRFNVRGIDDEANVANFCE 266
+ +L +I G Y ++S+ S +R GTRF+ RG++D+ +V+NF E
Sbjct: 176 SCCD-WLLKIICGVVTIRTVYASHKQAKACLVSRVSCERTGTRFHTRGVNDDGHVSNFVE 234
Query: 267 TEFIMYSEEYCFAVTEIRGSVPVFWEQDTALINPK-VTITRSVEATQSTFDEHFKRLIQK 325
TE ++Y ++ + +IRGSVP+FWEQ + + + R +EA FD H L ++
Sbjct: 235 TEQMIYMDDGVSSFVQIRGSVPLFWEQPGLQVGSHHLRLHRGLEANAPAFDRHMVLLKEQ 294
Query: 326 YGPVHVVNLLSTKSSEIELTRRYREHFERSKSLKLNSEIFLTEFDFHKETKEEGFAAASK 385
YG VVNLL ++ E L R +++ S + + FDFH+ FA K
Sbjct: 295 YGQQVVVNLLGSRGGEEVLNRAFKKLLWASCHA---GDTPMINFDFHQ------FAKGGK 345
Query: 386 I--MPTLERSILENGYFSYDVKEKKQLSE---QNGVFRTNCLDCLDRTNLIQQFISRYTF 440
+ + TL R L+ + +DV K + Q G R NCLDCLDRTN +Q FI+
Sbjct: 346 LEKLETLLRPQLKLHWEDFDVFTKGENVSPRFQKGTLRMNCLDCLDRTNTVQSFIALEVL 405
Query: 441 ILFLEDFQLIKPKLPLIEEYDWYQKHNNIWADHGDAVSQIYTGTNALKSSFSRKGKMSFA 500
L L+ L P+++ + + +W+ +G ++S+++TG+ AL+ K K+
Sbjct: 406 HLQLKTLGLSSK--PIVDRF--VESFKAMWSLNGHSLSKVFTGSRALEG----KAKV--- 454
Query: 501 GALSDATKSVSRMYINNFMDKNKQMNIDALL-----GRLPHQHSVELFDP----INDYVN 551
G L D +S+SR +NF D KQ I LL G L D + +
Sbjct: 455 GKLKDGARSMSRTIQSNFFDGVKQEAIKLLLVGDVYGEEVADKGGMLLDSTALLVTPRIL 514
Query: 552 EELRKQEAQFTTTSNIKILCGTFNVNG-------LTKSVDLSEWLYPIGK---------- 594
+ + +++++FT I+I GT+NVNG + ++ +L++WL +
Sbjct: 515 KAMTERQSEFTNFKRIRIAMGTWNVNGGKQFRSNVLRTAELTDWLLDSPQLSGATDSQDD 574
Query: 595 RYLPDIVVLGLQEVIELNASSILNVDTSKSQFWKDLVHSCLNKHENYIMLRAEQMSSLII 654
DI +G +E++EL+A +I+N T+ + W + + +++ YI+L + Q+ + +
Sbjct: 575 SSPADIFAVGFEEMVELSAGNIVNASTTNKKMWGEQLQKAISRSHRYILLTSAQLVGVCL 634
Query: 655 LFFVKADKVGNVKRVEGSSKKTGLGGMTGNKGAVAIRFDYGSTSFCFINAHLSAGVNNVE 714
FV+ V ++ V + KTG+GG GNKGAV IRF + STSFCFI +HL+AG + V+
Sbjct: 635 YIFVRPYHVPFIRDVAIDTVKTGMGGKAGNKGAVGIRFQFHSTSFCFICSHLTAGQSQVK 694
Query: 715 ERRSDYESITKGISFSRSKRIDHHNSTFWLGDLNYRIELPNEKVRSILSLPDNADLDKLL 774
ER DY+ IT+ + F + + H+ FW GD NYRI+L E+V + D KLL
Sbjct: 695 ERNEDYKEITQKLCFPMGRNVFSHDYVFWCGDFNYRIDLTYEEVFYFVK---RQDWKKLL 751
Query: 775 EHDQLTSEMASESVFKGFMEPSIQFRPTYKYDHGTDRYDTSEKARIPSWTDRILYKGENL 834
E DQL + +S +FK F E +I F PTYKYD G+ YDTS+K R P+WTDR+L+
Sbjct: 752 EFDQLQLQKSSGKIFKDFHEGAINFGPTYKYDVGSAAYDTSDKCRTPAWTDRVLW-WRKK 810
Query: 835 QPMAYSDAKLNLSD 848
P + +LNL D
Sbjct: 811 HPFDKTAGELNLLD 824
>CE28239 [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (synaptojanin)
INP51/INP52/INP53 family
Length = 1113
Score = 369 bits (948), Expect = e-101
Identities = 259/828 (31%), Positives = 406/828 (48%), Gaps = 87/828 (10%)
Query: 58 LEIHGFIGLIELEGSIFIGTITGKSEVASPIPGE-TVNKIYGVDFFCLDSNRWDFVEFDS 116
+E + +++ G + + IT V + G +V ++YG D + + VEF
Sbjct: 48 VERRSYQKIVDAYGILGVLAITKDEAVLVAVTGVLSVGQLYGADILKITN-----VEF-- 100
Query: 117 NGFPIIPEEEYASSSNQQQQHPCHDLKKLLSNGSFYYSS--DFDLTSLLQSRGLNQHSLS 174
I + S N + DL++LLS+ FY+SS +DLT Q R S
Sbjct: 101 -----ISLRTFGSVENVDSR--IIDLQRLLSSQMFYFSSLQSYDLTRSAQHRD------S 147
Query: 175 FDNYQEEYMWNSFLMQEIITFRNHLDDKAKQIMDDEGFLTTVIRGFAETFPSYIGRMPVN 234
D + WN L +F+ + +D + +L + G Y+G
Sbjct: 148 HDCSDARFFWNRSLH---FSFQRYG-------IDTDNWLLKCMAGSVLVRVVYVGANTGR 197
Query: 235 LTMISKQSWKRAGTRFNVRGIDDEANVANFCETEFIMYSEEYCFAVTEIRGSVPVFWEQD 294
+ +IS+ S +R GTRFNVRG + NVANF ETE ++ +E ++ +IRGS+P+FWEQ
Sbjct: 198 VALISRLSCERVGTRFNVRGANYLGNVANFVETEQLLLFDEKECSLLQIRGSIPLFWEQP 257
Query: 295 TALINPKVTITRSVEATQSTFDEHFKRLIQKYGPVHVVNLLSTKSSEIELTRRYREHFER 354
+ R+ E + + H +L +YG +VNLL K E L ++ +
Sbjct: 258 GVNVGSHKVKLRAFETSLPAYHRHLSQLQHRYGEFAIVNLLGRKEGERVLGDAFKTQHKS 317
Query: 355 SKSLKLNSEIFLTEFDFHKETKEEGFAAASKIMPTLERSILENGYFSYDVKEKKQLSEQN 414
S L + +FD+H + K A ++ + + ++G+F Y + K+ + Q
Sbjct: 318 SHFAPL---VDFIDFDYHAQMKISKEAIV-QLKKKMSPHMTKHGFF-YSMG-KEIVKRQT 371
Query: 415 GVFRTNCLDCLDRTNLIQQFISRYTFILFLEDFQLIKPKLPLIEEYDWYQKHNNIWADHG 474
GV RTNCLDCLDRTN +Q I + L K+ + + + + ++W +G
Sbjct: 372 GVIRTNCLDCLDRTNAVQTAIGLQMSHDQVAFLNLNAGKVNVEQRVEEILR--DLWQKNG 429
Query: 475 DAVSQIYTGTNALKSSFSRKGKMSFAGALSDATKSVSRMYINNFMDKNKQMNIDALLGRL 534
D S IY GT AL L DA++S++R NN MD KQ + D L
Sbjct: 430 DQCSTIYAGTGALDGK----------SKLKDASRSLARTIQNNLMDGAKQESFDLFLTGA 479
Query: 535 PHQHSVELFDP---------INDYVN--EELRKQEAQFTTTSNIKILCGTFNVNG----- 578
+ LFD I +Y + +L ++ + +IKI GT+NVNG
Sbjct: 480 AYDP--RLFDRACNILPPSLIQEYADAVSQLVERSPEIAEPQSIKIFVGTWNVNGGKNIH 537
Query: 579 ---LTKSVDLSEWLYP--------IGKRYLPDIVVLGLQEVIELNASSILNVDTSKSQFW 627
LS W++ + L DIV +G++E+++LNAS+++ T+ + W
Sbjct: 538 NVAFRNESSLSHWIFANSMTRLVSVEDEQLADIVAIGVEELVDLNASNMVKASTTNQRMW 597
Query: 628 KDLVHSCLNKHENYIMLRAEQMSSLIILFFVKADKVGNVKRVEGSSKKTGLGGMTGNKGA 687
+ + L++ ++++ +EQ+ + + F + +K +S KTG+GG TGNKG+
Sbjct: 598 CESIRKTLSEKAPFVLIGSEQLVGVCLFLFARPRVSPYLKDFAVASVKTGMGGATGNKGS 657
Query: 688 VAIRFDYGSTSFCFINAHLSAGVNNVEERRSDYESITKGISFSRSKRIDHHNSTFWLGDL 747
VA R STS CFI +H +AG N + +R D+ + K I F + ID H+ FWLGD
Sbjct: 658 VAFRIVVFSTSICFICSHFAAGQNEIRDRNEDFATTLKKIRFPLGREIDSHDVIFWLGDF 717
Query: 748 NYRIELPNEKVRSILSLPDNADLDKLLEHDQLTSEMASESVFKGFMEPSIQFRPTYKYDH 807
NYRI L ++V++ + N D KL+E+DQLT + A F GF E + F PTYKYD
Sbjct: 718 NYRINLSGDEVKNAVR---NGDYAKLVENDQLTQQKALGQTFVGFNEGQLTFAPTYKYDT 774
Query: 808 GTDRYDTSEKARIPSWTDRILYKGE----NLQPMAYSDAKLNLSDHKP 851
+D YDTSEK R P+WTDRIL+K + Q ++Y ++L SDH+P
Sbjct: 775 FSDDYDTSEKCRAPAWTDRILWKDQRKKGKTQLLSYDRSELKTSDHRP 822
>CE29050 [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (synaptojanin)
INP51/INP52/INP53 family
Length = 1119
Score = 365 bits (938), Expect = e-100
Identities = 258/834 (30%), Positives = 406/834 (47%), Gaps = 93/834 (11%)
Query: 58 LEIHGFIGLIELEGSIFIGTITGKSEVASPIPGE-TVNKIYGVDFFCLDSNRWDFVEFDS 116
+E + +++ G + + IT V + G +V ++YG D + + VEF
Sbjct: 48 VERRSYQKIVDAYGILGVLAITKDEAVLVAVTGVLSVGQLYGADILKITN-----VEF-- 100
Query: 117 NGFPIIPEEEYASSSNQQQQHPCHDLKKLLSNGSFYYSS--DFDLTSLLQSRGLNQHSLS 174
I + S N + DL++LLS+ FY+SS +DLT Q R S
Sbjct: 101 -----ISLRTFGSVENVDSR--IIDLQRLLSSQMFYFSSLQSYDLTRSAQHRD------S 147
Query: 175 FDNYQEEYMWNSFLMQEIITFRNHLDDKAKQIMDDEGFLTTVIRGFAETFPSYIGRMPVN 234
D + WN L +F+ + +D + +L + G Y+G
Sbjct: 148 HDCSDARFFWNRSLH---FSFQRYG-------IDTDNWLLKCMAGSVLVRVVYVGANTGR 197
Query: 235 LTMISKQSWKRAGTRFNVRGIDDEANVANFCETEFIMYSEEYCFAVTEIRGSVPVFWEQD 294
+ +IS+ S +R GTRFNVRG + NVANF ETE ++ +E ++ +IRGS+P+FWEQ
Sbjct: 198 VALISRLSCERVGTRFNVRGANYLGNVANFVETEQLLLFDEKECSLLQIRGSIPLFWEQP 257
Query: 295 TALINPKVTITRSVEATQSTFDEHFKRLIQKYGPVHVVNLLSTKSSEIELTRRYREHFER 354
+ R+ E + + H +L +YG +VNLL K E L ++ +
Sbjct: 258 GVNVGSHKVKLRAFETSLPAYHRHLSQLQHRYGEFAIVNLLGRKEGERVLGDAFKTQHKS 317
Query: 355 SKSLKLNSEIFLTEFDFHKETKEEGFAAASKIMPTLERSILENGYFSYDVKEKKQLSEQN 414
S L + +FD+H + K A ++ + + ++G+F Y + K+ + Q
Sbjct: 318 SHFAPL---VDFIDFDYHAQMKISKEAIV-QLKKKMSPHMTKHGFF-YSMG-KEIVKRQT 371
Query: 415 GVFRTNCLDCLDRTNLIQQFISRYTFILFLEDFQLIKPKLPLIEEYDWYQKHNNIWADHG 474
GV RTNCLDCLDRTN +Q I + L K+ + + + + ++W +G
Sbjct: 372 GVIRTNCLDCLDRTNAVQTAIGLQMSHDQVAFLNLNAGKVNVEQRVEEILR--DLWQKNG 429
Query: 475 DAVSQIYTGTNALKSSFSRKGKMSFAGALSDATKSVSRMYINNFMDKNKQMNIDALLGRL 534
D S IY GT AL L DA++S++R NN MD KQ + D L
Sbjct: 430 DQCSTIYAGTGALDGK----------SKLKDASRSLARTIQNNLMDGAKQESFDLFLTGA 479
Query: 535 PHQHSVELFDPI---------------NDYVN--EELRKQEAQFTTTSNIKILCGTFNVN 577
+ LFD ++Y + +L ++ + +IKI GT+NVN
Sbjct: 480 AYDP--RLFDRACNILPPSLIQESYYYHEYADAVSQLVERSPEIAEPQSIKIFVGTWNVN 537
Query: 578 G--------LTKSVDLSEWLYP--------IGKRYLPDIVVLGLQEVIELNASSILNVDT 621
G LS W++ + L DIV +G++E+++LNAS+++ T
Sbjct: 538 GGKNIHNVAFRNESSLSHWIFANSMTRLVSVEDEQLADIVAIGVEELVDLNASNMVKAST 597
Query: 622 SKSQFWKDLVHSCLNKHENYIMLRAEQMSSLIILFFVKADKVGNVKRVEGSSKKTGLGGM 681
+ + W + + L++ ++++ +EQ+ + + F + +K +S KTG+GG
Sbjct: 598 TNQRMWCESIRKTLSEKAPFVLIGSEQLVGVCLFLFARPRVSPYLKDFAVASVKTGMGGA 657
Query: 682 TGNKGAVAIRFDYGSTSFCFINAHLSAGVNNVEERRSDYESITKGISFSRSKRIDHHNST 741
TGNKG+VA R STS CFI +H +AG N + +R D+ + K I F + ID H+
Sbjct: 658 TGNKGSVAFRIVVFSTSICFICSHFAAGQNEIRDRNEDFATTLKKIRFPLGREIDSHDVI 717
Query: 742 FWLGDLNYRIELPNEKVRSILSLPDNADLDKLLEHDQLTSEMASESVFKGFMEPSIQFRP 801
FWLGD NYRI L ++V++ + N D KL+E+DQLT + A F GF E + F P
Sbjct: 718 FWLGDFNYRINLSGDEVKNAVR---NGDYAKLVENDQLTQQKALGQTFVGFNEGQLTFAP 774
Query: 802 TYKYDHGTDRYDTSEKARIPSWTDRILYKGE----NLQPMAYSDAKLNLSDHKP 851
TYKYD +D YDTSEK R P+WTDRIL+K + Q ++Y ++L SDH+P
Sbjct: 775 TYKYDTFSDDYDTSEKCRAPAWTDRILWKDQRKKGKTQLLSYDRSELKTSDHRP 828
>Hs22045277 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 652
Score = 213 bits (543), Expect = 1e-54
Identities = 120/339 (35%), Positives = 184/339 (53%), Gaps = 14/339 (4%)
Query: 536 HQHSVELFDPINDYVNEELRKQEAQFTTTSNIKILCGTFNVNGLTKSVDLSEWLYPIGKR 595
H S++ F + V L ++E +T N + GT+NVNG + L WL
Sbjct: 234 HILSMQKFGLRDTIVKSHLLQKEEDYTYIQNFRFFAGTYNVNGQSPKECLRLWLS--NGI 291
Query: 596 YLPDIVVLGLQEVIELNASSILNVDTSKSQFWKDLVHSCLNKHENYIMLRAEQMSSLIIL 655
PD+ +G QE ++L+ + DT K + W V L+ Y ++ ++ +++L
Sbjct: 292 QAPDVYCVGFQE-LDLSKEAFFFHDTPKEEEWFKAVSEGLHPDAKYAKVKLIRLVGIMLL 350
Query: 656 FFVKADKVGNVKRVEGSSKKTGLGGMTGNKGAVAIRFDYGSTSFCFINAHLSAGVNNVEE 715
+VK + + VE + TG+ G GNKG VAIRF + +TS C +N+HL+A + E
Sbjct: 351 LYVKQEHAAYISEVEAETVGTGIMGRMGNKGGVAIRFQFHNTSICVVNSHLAAHIEEYER 410
Query: 716 RRSDYESITKGISFSRSK------RIDHHNSTFWLGDLNYRIE-LPNEKVRSILSLPDNA 768
R DY+ I + F + I +H+ WLGDLNYRIE L EKV+ ++ +
Sbjct: 411 RNQDYKDICSRMQFCQPDPSLPPLTISNHDVILWLGDLNYRIEELDVEKVKKLI---EEK 467
Query: 769 DLDKLLEHDQLTSEMASESVFKGFMEPSIQFRPTYKYDHGTDRYDTSEKARIPSWTDRIL 828
D L +DQL ++A+++VF+GF E + F+PTYKYD G+D +DTSEK R P+W DRIL
Sbjct: 468 DFQMLYAYDQLKIQVAAKTVFEGFTEGELTFQPTYKYDTGSDDWDTSEKCRAPAWCDRIL 527
Query: 829 YKGENLQPMAY-SDAKLNLSDHKPXXXXXXXXXXFIDEE 866
+KG+N+ ++Y S L SDHKP +++E
Sbjct: 528 WKGKNITQLSYQSHMALKTSDHKPVSSVFDIGVRVVNDE 566
>7300754 [I] KOG1890 Phosphoinositide phosphatase SAC1
Length = 987
Score = 207 bits (527), Expect = 7e-53
Identities = 120/384 (31%), Positives = 194/384 (50%), Gaps = 23/384 (5%)
Query: 150 SFYYSSDFDLTSLLQSRGLNQHSLSFDNYQEEYMWNSFLMQEIITFRNHLDDKAKQIMDD 209
SFY+S D D+T+ LQ S E + WN +++++I ++D
Sbjct: 204 SFYFSFDCDITNNLQRHEAKSEE-SQSQPDERFFWNKHMIRDLIN------------LND 250
Query: 210 EGFLTTVIRGFAETFPSYIGRMPVNLTMISKQSWKRAGTRFNVRGIDDEANVANFCETEF 269
+ ++ +I+GF + IG L ++S++S RAGTR+ RG+D++ N AN+ ETE
Sbjct: 251 KTWILPIIQGFMQVENCVIGNECFTLALVSRRSRHRAGTRYKRRGVDEKGNCANYVETEQ 310
Query: 270 IMYSEEYCFAVTEIRGSVPVFWEQDTALINPKVTITRSVEATQSTFDEHFKRLIQKYGPV 329
I+ + + T++RGSVP++W Q P + R V TQ F+ HF + ++ YG V
Sbjct: 311 ILSFRHHQLSFTQVRGSVPIYWSQPGYKYRPPPRLDRGVAETQQAFELHFTKELETYGRV 370
Query: 330 HVVNLLSTKSSEIELTRRYREHFERSKSLKLNSE-IFLTEFDFHKETKEEGFAAASKIMP 388
+VNL+ E + Y +H +KLN++ + FDFH + F S ++
Sbjct: 371 CIVNLVEQSGKEKTIGDAYADHV-----IKLNNDRLIYVTFDFHDYCRGMRFENVSALID 425
Query: 389 TLERSILENGYFSYDVKEKKQLSEQNGVFRTNCLDCLDRTNLIQQFISRYTFILFLEDFQ 448
+ G+ D ++ + Q VFR NC+DCLDRTN++Q I + L
Sbjct: 426 AVGPEAGAMGFHWRD--QRGMICNQKSVFRVNCMDCLDRTNVVQTAIGKAVLESQLVKLG 483
Query: 449 LIKPKLPLIEEYDWYQKHNNIWADHGDAVSQIYTGTNALKSSFSRKGKMSFAGALSDATK 508
L P P+ E+ +WA++GD +S+ Y GTNALK ++R G+ +G + D
Sbjct: 484 LSPPYTPIPEQLK--SPFMVLWANNGDIISRQYAGTNALKGDYTRTGERKISGMMKDGMN 541
Query: 509 SVSRMYINNFMDKNKQMNIDALLG 532
S +R Y+ F D +Q ID +LG
Sbjct: 542 SANRYYLARFKDSYRQATIDLMLG 565
>YKL212w [I] KOG1889 Putative phosphoinositide phosphatase
Length = 623
Score = 207 bits (526), Expect = 9e-53
Identities = 145/482 (30%), Positives = 242/482 (50%), Gaps = 42/482 (8%)
Query: 87 PIPGETVNKIYGVDFFCLDSNRWDFV--------EFDSNGFPIIPEEEYASSS-----NQ 133
P+ GE V + F L NR+ + F+ + F + + S+ +
Sbjct: 47 PVQGEVVKIASLMGFIKLKLNRYAIIANTVEETGRFNGHVFYRVLQHSIVSTKFNSRIDS 106
Query: 134 QQQHPCHDLKKLLSNGSFYYSSDFDLTSLLQSRGLNQHSLSFDNYQEEYMWNSFLMQEII 193
++ L+ L N +FY+S +DLT+ LQ + S+ E + WN +L +++
Sbjct: 107 EEAEYIKLLELHLKNSTFYFSYTYDLTNSLQRNEKVGPAASWKTADERFFWNHYLTEDLR 166
Query: 194 TFRNHLDDKAKQIMDDEGFLTTVIRGFAETFPSYIGRMPVNLTMISKQSWKRAGTRFNVR 253
F H D + + F+ VI G+A+T + + P+ L +I+++S RAGTR+ R
Sbjct: 167 NFA-HQDPRI------DSFIQPVIYGYAKTVDAVLNATPIVLGLITRRSIFRAGTRYFRR 219
Query: 254 GIDDEANVANFCETEFIMYSEE------YCFAVTEIRGSVPVFWEQDTAL-INPKVTI-T 305
G+D + NV NF ETE I+ +E + F+ + RGSVP++W + L P + +
Sbjct: 220 GVDKDGNVGNFNETEQILLAENPESEKIHVFSFLQTRGSVPIYWAEINNLKYKPNLVLGE 279
Query: 306 RSVEATQSTFDEHFKRLIQKYGPVHVVNLLSTKSSEIELTRRYREHFERSKSLKLNSEIF 365
S++AT+ FD+ K L YG ++VNL++ K E+ + +E +E + +I
Sbjct: 280 NSLDATKKHFDQQ-KEL---YGDNYLVNLVNQKGHELPV----KEGYESVVHALNDPKIH 331
Query: 366 LTEFDFHKETKEEGFAAASKIMPTLERSILENGYFSYDVKEKKQ-----LSEQNGVFRTN 420
FDFH E ++ + ++ LE+ L N F + V + ++EQ+ V RTN
Sbjct: 332 YVYFDFHHECRKMQWHRVKLLIDHLEKLGLSNEDFFHKVIDSNGNTVEIVNEQHSVVRTN 391
Query: 421 CLDCLDRTNLIQQFISRYTFILFLEDFQLIKPKLPLIEEYDWYQKHNNIWADHGDAVSQI 480
C+DCLDRTN++Q ++++ E ++ + + N+WAD+ DAVS
Sbjct: 392 CMDCLDRTNVVQSVLAQWVLQKEFESADVVATGSTWEDNAPLLTSYQNLWADNADAVSVA 451
Query: 481 YTGTNALKSSFSRKGKMSFAGALSDATKSVSRMYINNFMDKNKQMNIDALLGRL-PHQHS 539
Y+GT ALK+ F+R GK + GA +D S SR Y NN+ D +Q + D LG PH S
Sbjct: 452 YSGTGALKTDFTRTGKRTRLGAFNDFLNSASRYYQNNWTDGPRQDSYDLFLGGFRPHTAS 511
Query: 540 VE 541
++
Sbjct: 512 IK 513
>SPBC19F5.03 [I] KOG1889 Putative phosphoinositide phosphatase
Length = 598
Score = 203 bits (517), Expect = 1e-51
Identities = 132/402 (32%), Positives = 196/402 (47%), Gaps = 20/402 (4%)
Query: 141 DLKKLLSN----GSFYYSSDFDLTSLLQSRGLNQHSLS-FDNYQEEYMWNSFLMQEIITF 195
DL LL N G FY+S +DLT+ LQ ++ S + + WN F ++ I
Sbjct: 101 DLYNLLQNHLKTGPFYFSYTWDLTNSLQRSCTDEGKASPILRSDKRFFWNEFASKDFI-- 158
Query: 196 RNHLDDKAKQIMDDEGFLTTVIRGFAETFPSYIGRMPVNLTMISKQSWKRAGTRFNVRGI 255
D + F+T +I GF + + + + L +IS++S +RAGTR+ RG+
Sbjct: 159 -----DLIGAHSEVSLFITPMIYGFITSASTIVKGRTITLALISRRSKQRAGTRYFTRGL 213
Query: 256 DDEANVANFCETEFIMY----SEEYCFAVTEIRGSVPVFWEQDTALINPKVTITRSVEAT 311
D+ N ANF ETE I E ++ + RGSVP FW + L + + S
Sbjct: 214 DENGNPANFNETEQITIVSDEKSEVTYSHVQTRGSVPAFWAEVNNLRYKPLMVANSASMA 273
Query: 312 QSTFDEHFKRLIQKYGPVHVVNLLSTKSSEIELTRRYREHFERSKSLKLNSEIFLTEFDF 371
+ +HF I YG VVNL++ K E+ + + Y R N I FDF
Sbjct: 274 AAAAKKHFDEQISIYGDQVVVNLVNCKGHELPIKQLYENVIRRLD----NPHIHYHYFDF 329
Query: 372 HKETKEEGFAAASKIMPTLERSILENGYFSYDVKEKKQLSEQNGVFRTNCLDCLDRTNLI 431
HKE + S ++ ++ + E GY + D ++ + LS QNGV R+NC+DCLDRTN++
Sbjct: 330 HKECSHMRWDRVSLLLNEIQPELEEQGYTTLDTQKYRVLSRQNGVVRSNCMDCLDRTNVV 389
Query: 432 QQFISRYTFILFLEDFQLIKPKLPLIEEYDWYQKHNNIWADHGDAVSQIYTGTNALKSSF 491
Q I R+ L +I PL NIW+D+ D +S Y+GT ALK+ F
Sbjct: 390 QSCIGRWVLTNQLRKCGIIGATHPLRSVIPLDNIFCNIWSDNADYISLSYSGTGALKTDF 449
Query: 492 SRKGKMSFAGALSDATKSVSRMYINNFMDKNKQMNIDALLGR 533
+R G + GA +D S R +NNF D +Q D +LG+
Sbjct: 450 TRTGIRTRKGAFNDFVNSAKRYILNNFYDGARQDAYDLVLGQ 491
>7290234 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 850
Score = 200 bits (508), Expect = 1e-50
Identities = 132/385 (34%), Positives = 199/385 (51%), Gaps = 22/385 (5%)
Query: 537 QHSVEL---FDPINDY-----VNEELRKQEAQFTTTSNIKILCGTFNVNGLTKSVD---L 585
QH E F +NDY V +EL+K+E+++ +I I C T+NVN T S L
Sbjct: 147 QHDPETVLNFRWLNDYRQIGEVKQELKKRESEYIVYKDIIIYCATWNVNNKTCSDSNNPL 206
Query: 586 SEWLYPIGKRYLPDIVVLGLQEVIELNASSILN---VDTSKSQFWKDLVHSCLNKHENYI 642
WL K PDI +GLQE ++ ++LN V + Q W D + ++ Y
Sbjct: 207 RAWLACSEKP--PDIYAIGLQE-LDTPTKAMLNSTQVQAIEKQ-WIDKMMDSVHPDVEYE 262
Query: 643 MLRAEQMSSLIILFFVKADKVGNVKRVEGSSKKTGLGGMTGNKGAVAIRFDYGSTSFCFI 702
+L + ++ + ++ V+ ++ R S G+ GNKG VAI + CF+
Sbjct: 263 ILMSHRLVATMLTVIVRKQLRQHIIRCRPKSVARGIFNTLGNKGGVAISLQLNEGNICFV 322
Query: 703 NAHLSAGVNNVEERRSDYESITKGISFSRSKRIDHHNSTFWLGDLNYRIELPNEKVRSIL 762
N+HL+A + VEER DY +I +GI F + I H+ FW+GDLNYRI+ P + R
Sbjct: 323 NSHLAAHMGYVEERNQDYNAIVEGIRFDDGRTISDHDHIFWVGDLNYRIQEPPGQQRP-G 381
Query: 763 SLPDNADLDKLLEHDQLTSEMASESVFKGFMEPSIQFRPTYKYDHGTDRYDTSEKARIPS 822
L D + LL++DQL EM F+G+ E I+FRPTYKYD GTD YD+SEK R P+
Sbjct: 382 PLSDAQTYELLLQYDQLRQEMRRGKCFEGYTEGEIKFRPTYKYDPGTDNYDSSEKQRAPA 441
Query: 823 WTDRILYKGENLQPMAY-SDAKLNLSDHKPXXXXXXXXXXFIDE--ESKIQMTKKLYMDY 879
+ DR+L+KG ++ +AY S ++ SDHKP DE ++Q +D
Sbjct: 442 YCDRVLWKGTRIEQLAYNSIMEIRQSDHKPVYAVFQVKVKTRDEVKYKRVQEEVLKAVDK 501
Query: 880 KQSHPQDSGSINSALLDLELVDAKE 904
+++ Q ++ ++D V E
Sbjct: 502 RENDNQPQINVEKTVIDFGTVRFNE 526
>Hs13325072 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 901
Score = 196 bits (499), Expect = 1e-49
Identities = 110/319 (34%), Positives = 169/319 (52%), Gaps = 12/319 (3%)
Query: 554 LRKQEAQFTTTSNIKILCGTFNVNGLTKSVDLSEWLYPIGKRYLPDIVVLGLQEVIELNA 613
L K+E ++ + GT+NVNG + L WL PDI +G QE ++L+
Sbjct: 227 LAKREKEYVNIQTFRFFVGTWNVNGQSPDSGLEPWLNCDPNP--PDIYCIGFQE-LDLST 283
Query: 614 SSILNVDTSKSQFWKDLVHSCLNKHENYIMLRAEQMSSLIILFFVKADKVGNVKRVEGSS 673
+ ++ K Q W V L+ Y ++ ++ +++L F + D+ ++ + +
Sbjct: 284 EAFFYFESVKEQEWSMAVERGLHSKAKYKKVQLVRLVGMMLLIFARKDQCRYIRDIATET 343
Query: 674 KKTGLGGMTGNKGAVAIRFDYGSTSFCFINAHLSAGVNNVEERRSDYESITKGISFSRSK 733
TG+ G GNKG VA+RF + +T+FC +N+HL+A V + E R DY+ I +SF
Sbjct: 344 VGTGIMGKMGNKGGVAVRFVFHNTTFCIVNSHLAAHVEDFERRNQDYKDICARMSFVVPN 403
Query: 734 R------IDHHNSTFWLGDLNYRIELPNEKVRSILSLPDNADLDKLLEHDQLTSEMASES 787
+ I H WLGDLNYR+ +P+ + SL + DL +LL+ DQL + +
Sbjct: 404 QTLPQLNIMKHEVVIWLGDLNYRLCMPD--ANEVKSLINKKDLQRLLKFDQLNIQRTQKK 461
Query: 788 VFKGFMEPSIQFRPTYKYDHGTDRYDTSEKARIPSWTDRILYKGENLQPMAY-SDAKLNL 846
F F E I+F PTYKYD TDR+D+S K R+P+W DRIL++G N+ + Y S +L
Sbjct: 462 AFVDFNEGEIKFIPTYKYDSKTDRWDSSGKCRVPAWCDRILWRGTNVNQLNYRSHMELKT 521
Query: 847 SDHKPXXXXXXXXXXFIDE 865
SDHKP +DE
Sbjct: 522 SDHKPVSALFHIGVKVVDE 540
>Hs13325070 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 893
Score = 196 bits (499), Expect = 1e-49
Identities = 110/319 (34%), Positives = 169/319 (52%), Gaps = 12/319 (3%)
Query: 554 LRKQEAQFTTTSNIKILCGTFNVNGLTKSVDLSEWLYPIGKRYLPDIVVLGLQEVIELNA 613
L K+E ++ + GT+NVNG + L WL PDI +G QE ++L+
Sbjct: 227 LAKREKEYVNIQTFRFFVGTWNVNGQSPDSGLEPWLNCDPNP--PDIYCIGFQE-LDLST 283
Query: 614 SSILNVDTSKSQFWKDLVHSCLNKHENYIMLRAEQMSSLIILFFVKADKVGNVKRVEGSS 673
+ ++ K Q W V L+ Y ++ ++ +++L F + D+ ++ + +
Sbjct: 284 EAFFYFESVKEQEWSMAVERGLHSKAKYKKVQLVRLVGMMLLIFARKDQCRYIRDIATET 343
Query: 674 KKTGLGGMTGNKGAVAIRFDYGSTSFCFINAHLSAGVNNVEERRSDYESITKGISFSRSK 733
TG+ G GNKG VA+RF + +T+FC +N+HL+A V + E R DY+ I +SF
Sbjct: 344 VGTGIMGKMGNKGGVAVRFVFHNTTFCIVNSHLAAHVEDFERRNQDYKDICARMSFVVPN 403
Query: 734 R------IDHHNSTFWLGDLNYRIELPNEKVRSILSLPDNADLDKLLEHDQLTSEMASES 787
+ I H WLGDLNYR+ +P+ + SL + DL +LL+ DQL + +
Sbjct: 404 QTLPQLNIMKHEVVIWLGDLNYRLCMPD--ANEVKSLINKKDLQRLLKFDQLNIQRTQKK 461
Query: 788 VFKGFMEPSIQFRPTYKYDHGTDRYDTSEKARIPSWTDRILYKGENLQPMAY-SDAKLNL 846
F F E I+F PTYKYD TDR+D+S K R+P+W DRIL++G N+ + Y S +L
Sbjct: 462 AFVDFNEGEIKFIPTYKYDSKTDRWDSSGKCRVPAWCDRILWRGTNVNQLNYRSHMELKT 521
Query: 847 SDHKPXXXXXXXXXXFIDE 865
SDHKP +DE
Sbjct: 522 SDHKPVSALFHIGVKVVDE 540
>CE20170 [I] KOG1890 Phosphoinositide phosphatase SAC1
Length = 783
Score = 191 bits (484), Expect = 7e-48
Identities = 139/487 (28%), Positives = 236/487 (47%), Gaps = 41/487 (8%)
Query: 141 DLKKLLSNGS-FYYSSDFDLTSLLQSRGLNQHSLSFDNYQEEYMWNSFLMQEIITFRNHL 199
D+ KL ++ FY+ D+T Q + + ++ + WN ++ + + +
Sbjct: 144 DVLKLFNDSKDFYFCRSRDVTISSQKYFEKREA---HTSEDSFFWNKRMVGNLGEAK--I 198
Query: 200 DDKAK-QIMDDEGFLTTVIRGFAETFPSYIGRMPVNLTMISKQSWKRAGTRFNVRGIDDE 258
DK IM +G++ T + +Y+ +T+IS++S +RAG R+ RGID+
Sbjct: 199 SDKFTCPIM--QGYVATSQLEITDQINAYL-----TITIISRRSTRRAGARYLRRGIDEA 251
Query: 259 ANVANFCETEFIMYSEEYCFAVTEIRGSVPVFWEQDTALINPKVTITRSVEATQSTFDEH 318
+NVANF ETE I+ E+ + + RGS+PVFW Q P + I RSVE T F EH
Sbjct: 252 SNVANFVETELILNIFEHELSFVQCRGSIPVFWSQRGFKYRPPLIINRSVEETHGVFTEH 311
Query: 319 FKRLIQKYG-PVHVVNLLSTKSSEIELTRRYREHFERSKSLKLNSEIFLTEFDFHKETKE 377
FKRL Y P+ V+L+ + E+ L +R+ EH ++ ++++ FD H+ +
Sbjct: 312 FKRLKAHYDTPLVAVSLVDQRGRELPLAQRFLEHCVKAD----DNDVTFFSFDLHQHCRG 367
Query: 378 EGFAAASKIMPTLERSILENGYFSYDVKEKKQLSEQNGVFRTNCLDCLDRTNLIQQFISR 437
F ++ ++E ++ G+ D K + + Q GV RTNC+DCLDRTNL+Q IS
Sbjct: 368 LNFQKLQTLISSMEETLKTIGFCWVD-KTGEVVQSQKGVVRTNCIDCLDRTNLVQGQISL 426
Query: 438 YTFILFLEDFQLIKPKLPLIEEYD-WYQKHNNIWADHGDAVSQIYTGTNALKSSFSRKGK 496
+ + L+ Q + PL E + Q +WAD+GD +S Y GT ALK +R G+
Sbjct: 427 F---VVLQQAQRLGIFGPLCEPPEVLVQTMQTMWADNGDVISTQYAGTAALKGDVTRNGE 483
Query: 497 MSFAGALSDATKSVSRMYINNFMDKNKQMNIDALLGRLPHQHSVELFDPINDYVNEE--- 553
G + D S SR Y+ + D +Q I+ + G+ + E + N+ EE
Sbjct: 484 RKLMGVMKDGYNSASRYYLTHTKDAQRQKAINIVTGQTEADENAE--EEENEKEEEENIS 541
Query: 554 -LRKQEAQFTTTSNIKILCGTFNVNGLTKSVDLSEWL-----------YPIGKRYLPDIV 601
+ + QF + ++ G +N S ++ + Y I + D+
Sbjct: 542 RMVTETIQFLVPTQQTVIAGWGLINAFQSSDEIDTVVILTRSNLYIVTYEIDGEKMTDVQ 601
Query: 602 VLGLQEV 608
++ L+++
Sbjct: 602 IVALEDI 608
>Hs7662338 [I] KOG1889 Putative phosphoinositide phosphatase
Length = 587
Score = 185 bits (469), Expect = 4e-46
Identities = 126/396 (31%), Positives = 193/396 (47%), Gaps = 22/396 (5%)
Query: 142 LKKLLSNGSFYYSSDFDLTSLLQ-----SRGLNQHSLSFDNYQEEYMWNSFLMQEIITFR 196
L +L+ FY+S+ +DLT LQ S + SL + + ++WN L++E+
Sbjct: 122 LNHVLNVDGFYFSTTYDLTHTLQRLSNTSPEFQEMSL-LERADQRFVWNGHLLREL---- 176
Query: 197 NHLDDKAKQIMDDEGFLTTVIRGFAETFPSYIGRMPVNLTMISKQSWKRAGTRFNVRGID 256
+ F V+ GF I + +IS++S RAG R+ VRGID
Sbjct: 177 -------SAQPEVHRFALPVLHGFITMHSCSINGKYFDWILISRRSCFRAGVRYYVRGID 229
Query: 257 DEANVANFCETEFIMYSEEYCFAVTEIRGSVPVFWEQDTALINPKVTITRSVEATQSTFD 316
E + ANF ETE I++ + + RGS+PVFW Q L + V F
Sbjct: 230 SEGHAANFVETEQIVHYNGSKASFVQTRGSIPVFWSQRPNLKYKPLPQISKVANHMDGFQ 289
Query: 317 EHFKRLIQKYGPVHVVNLLSTKSSEIELTRRYREHFERSKSLKLNSEIFLTEFDFHKETK 376
HF + YG ++NL++ K SE L + F S + + FDFHKE K
Sbjct: 290 RHFDSQVIIYGKQVIINLINQKGSEKPL----EQTFATMVSSLGSGMMRYIAFDFHKECK 345
Query: 377 EEGFAAASKIMPTLERSILENGYFSYDVKEKKQLSEQNGVFRTNCLDCLDRTNLIQQFIS 436
+ S ++ + E YF D + ++ Q GVFR+NC+DCLDRTN+IQ ++
Sbjct: 346 NMRWDRLSILLDQVAEMQDELSYFLVD-SAGQVVANQEGVFRSNCMDCLDRTNVIQSLLA 404
Query: 437 RYTFILFLEDFQLIKPKLPLIEEYDWYQKHNNIWADHGDAVSQIYTGTNALKSSFSRKGK 496
R + L+ ++ L E+ ++ + + N WAD+ +A ++ Y GT ALK+ F+R GK
Sbjct: 405 RRSLQAQLQRLGVLHVGQKLEEQDEFEKIYKNAWADNANACAKQYAGTGALKTDFTRTGK 464
Query: 497 MSFAGALSDATKSVSRMYINNFMDKNKQMNIDALLG 532
+ G + D S+ R Y NNF D +Q +ID LG
Sbjct: 465 RTHLGLIMDGWNSMIRYYKNNFSDGFRQDSIDLFLG 500
>CE09807 [I] KOG1889 Putative phosphoinositide phosphatase
Length = 591
Score = 185 bits (469), Expect = 4e-46
Identities = 126/405 (31%), Positives = 196/405 (48%), Gaps = 34/405 (8%)
Query: 142 LKKLLSNGSFYYSSDFDLTSLLQSRGLNQHSL-----SFDNYQEEYMWNSFLMQEIITFR 196
L +LS G FYYS+ D++ Q N L D E ++WN L+ +I
Sbjct: 127 LTHVLSIGGFYYSTTLDISRTFQWLQENAVPLFKTRSMLDRASERFIWNGHLLSQI---- 182
Query: 197 NHLDDKAKQIMDDEGFLTTVIRGFAETFPSYIGRMPVNLTMISKQSWKRAGTRFNVRGID 256
+Q+ E + VI GF + + LT+IS++S RAG RF RG+D
Sbjct: 183 -------RQVPGAERYTLPVIHGFIGQNRVNVNGKEIKLTIISRRSIYRAGVRFYKRGVD 235
Query: 257 DEANVANFCETEFIMY---SEEYCFAVTEIRGSVPVFWEQDTALINPKVTITRSVEATQS 313
+ + ANF ETE I+ +++ + ++RGS+P+ W Q L + + + +
Sbjct: 236 VDGHAANFVETEQIVEYTNPDKHLTSFVQLRGSIPLLWTQKPNLRWQPMPTLKPTDDQLA 295
Query: 314 TFDEHFKRLIQKYGPVHV-VNLLSTKSSEIELTRRYREHFERSKSLKLNSEIFLTEFDFH 372
F+ F Q YG HV VNL++ K E ++ E R +++ + +FDFH
Sbjct: 296 AFNRAFSWHKQHYGGKHVIVNLVNQKGREKKVGGEL-ERISRQANIEF---VRYHQFDFH 351
Query: 373 KETKEEGFAAASKIMPTLERSILENGYFSYDVKEKKQLSEQNGVFRTNCLDCLDRTNLIQ 432
KE + + L + I GYF + Q G FRTNC+DCLDRTN++Q
Sbjct: 352 KECHSMQWHRIDLLREQLSQEISSFGYFYLSPNSMETSRFQRGFFRTNCMDCLDRTNVVQ 411
Query: 433 QFISRYTFILFLEDFQLIKPK-----LPLIEEYDWYQKHNNIWADHGDAVSQIYTGTNAL 487
++R + L ++ + +PL+E+ +WAD+GD S+ Y GT AL
Sbjct: 412 SMLARESLTEQLRMLGILYSEQKVQDIPLLED-----AFKQMWADNGDECSRQYAGTGAL 466
Query: 488 KSSFSRKGKMSFAGALSDATKSVSRMYINNFMDKNKQMNIDALLG 532
K+ F+R G+ ++ GA+ D +VSR NNF D +Q +ID LG
Sbjct: 467 KADFTRHGRRTYVGAMKDGVNAVSRYVRNNFGDGYRQDSIDLFLG 511
>Hs7662414 [I] KOG1890 Phosphoinositide phosphatase SAC1
Length = 1132
Score = 182 bits (463), Expect = 2e-45
Identities = 121/423 (28%), Positives = 201/423 (46%), Gaps = 54/423 (12%)
Query: 142 LKKLLSNGSFYYSSDFDLTSLLQ--SRGLNQHSLSFDNYQEEYMWNSFLMQEIITFRNHL 199
LK + + SFYYS +DLT+ +Q S G + + + WN +++Q++
Sbjct: 167 LKMFMDSESFYYSLTYDLTNSVQRQSTGERDGRPLWQKVDDRFFWNKYMIQDLTEIGTP- 225
Query: 200 DDKAKQIMDDEGFLTTVIRGFAETFPSYIGRMPVNLT----------------------- 236
D + ++ +I+GF + I + VN T
Sbjct: 226 --------DVDFWIIPMIQGFVQ-----IEELVVNYTESSDDEKSSPETPPQESTCVDDI 272
Query: 237 -------MISKQSWKRAGTRFNVRGIDDEANVANFCETEFIMYSEEYCFAVTEIRGSVPV 289
+IS++S RAG R+ RG+D NVAN+ ETE +++ + + + RGSVPV
Sbjct: 273 HPRFLVALISRRSRHRAGMRYKRRGVDKNGNVANYVETEQLIHVHNHTLSFVQTRGSVPV 332
Query: 290 FWEQDTALINPKVTITRSVEATQSTFDEHFKRLIQKYGPVHVVNLLSTKSSEIELTRRYR 349
FW Q NP+ + RS + T + F HF+ + Y ++NL+ E +
Sbjct: 333 FWSQVGYRYNPRPRLDRSEKETVAYFCAHFEEQLNIYKKQVIINLVDQAGRE----KIIG 388
Query: 350 EHFERSKSLKLNSEIFLTEFDFHKETKEEGFAAASKIMPTLERSILENGYFSYDVKEKKQ 409
+ + + L NS + FDFH+ + F + + IL+ + D E
Sbjct: 389 DAYLKQVLLFNNSHLTYVSFDFHEHCRGMKFENVQTLTDAIYDIILDMKWCWVD--EAGV 446
Query: 410 LSEQNGVFRTNCLDCLDRTNLIQQFISRYTFILFLEDFQLIKPKLPLIEEYDWYQKHNNI 469
+ +Q G+FR NC+DCLDRTN++Q I+R L+ ++ P+ PL + + + + +
Sbjct: 447 ICKQEGIFRVNCMDCLDRTNVVQAAIARVVMEQQLKKLGVMPPEQPLPVKCN--RIYQIM 504
Query: 470 WADHGDAVSQIYTGTNALKSSFSRKGKMSFAGALSDATKSVSRMYINNFMDKNKQMNIDA 529
WA++GD++S+ Y GT ALK F+R G+ AG + D S +R Y+N F D +Q ID
Sbjct: 505 WANNGDSISRQYAGTAALKGDFTRTGERKLAGVMKDGVNSANRYYLNRFKDAYRQAVIDL 564
Query: 530 LLG 532
+ G
Sbjct: 565 MQG 567
>At5g66020 [I] KOG1889 Putative phosphoinositide phosphatase
Length = 549
Score = 179 bits (453), Expect = 3e-44
Identities = 144/482 (29%), Positives = 225/482 (45%), Gaps = 63/482 (13%)
Query: 60 IHGFIGLIELEGSIFIGTITGKSEVASPIPGETVNKIYGVDFFCLDSNRWDFVEFDSNGF 119
I G +G+++L ++ +T V S + G + KI + F D + +
Sbjct: 62 IFGVVGMLKLLAGSYLVVVTESESVGSFL-GHPIYKINSLKFLPCDHSLEN--------- 111
Query: 120 PIIPEEEYASSSNQQQQHPCHDLKKLLS----NGSFYYSSDFDLTSLLQS-RGLNQHSLS 174
P EE Q++ D +LLS Y+S + +LT Q L S
Sbjct: 112 ---PHEE-------QKKMETDDYSRLLSVAERTTGLYFSYEINLTLTAQRLHDLGDESKL 161
Query: 175 FDNYQE---EYMWNSFLMQEIITFRNHLDDKAKQIMDDEGFLTTVIRGFAETFPSYIGRM 231
+++ ++WN+++++ +I D+K Q FL VI+G
Sbjct: 162 LPLWRQAEPRFLWNNYMLEVLI------DNKLDQ------FLLPVIQGNI---------- 199
Query: 232 PVNLTMISKQSWKRAGTRFNVRGIDDEANVANFCETEFIMYSEEYCFAVTEIRGSVPVFW 291
V++T+I+++ +R GTR RG D + VANF ETE I+ Y + +IRGS+P W
Sbjct: 200 -VDITLIARRCSRRNGTRMWRRGADPDGYVANFVETEQIVRMNGYTSSFVQIRGSMPFMW 258
Query: 292 EQDTALI-NPKVTITRSVEATQSTFDEHFKRLIQKYGPVHVVNLLSTKSSEIELTRRYRE 350
EQ L PK I + EA + + HF L +KYG V V+L + E +
Sbjct: 259 EQIVDLTYKPKFEIVQPEEAVRIA-ERHFLDLRKKYGSVLAVDLHGGEGRLSERFAGAMQ 317
Query: 351 HFERSKSLKLNSEIFLTEFDFHKETKEEGFAAASKIMPTLERSILENGYFSYDVKEKKQL 410
H S+ L FDFH F + + +E + +NGYF + K +K +
Sbjct: 318 HITASRYL---------HFDFHHICGHIHFERLAILYEQMEDFLEKNGYFLLNEKGEK-M 367
Query: 411 SEQNGVFRTNCLDCLDRTNLIQQFISRYTFILFLEDFQLIKPKLPLIEEYDWYQKHNNIW 470
EQ G+ RTNC+DCLDRTN+ Q I R L L+ + + + ++ + + +W
Sbjct: 368 KEQLGIVRTNCIDCLDRTNVTQSMIGRKLLELQLKRIGVFGAEETIRSHQNFDECYKILW 427
Query: 471 ADHGDAVSQIYTGTNALKSSFSRKGKMSFAGALSDATKSVSRMYINNFMDKNKQMNIDAL 530
A+HGD +S Y+GT ALK F R G+ + G L D +++R Y+NNF D KQ ID +
Sbjct: 428 ANHGDDISIQYSGTPALKGDFVRYGQRTIQGVLQDGWNALARYYLNNFADGTKQDAIDLV 487
Query: 531 LG 532
G
Sbjct: 488 QG 489
>At3g51830 [I] KOG1889 Putative phosphoinositide phosphatase
Length = 599
Score = 178 bits (452), Expect = 4e-44
Identities = 127/419 (30%), Positives = 193/419 (45%), Gaps = 31/419 (7%)
Query: 142 LKKLLSNGSFYYSSDFDLTSLLQSR-----GLNQ-------HSLSFDNYQEEYMWNSFLM 189
L+ L + Y+S + DLT LQ R G N+ L Y+WN L+
Sbjct: 129 LQALETTPGLYFSYETDLTLNLQRRCKLAEGWNRKPMWKQAEGLFACQADPRYVWNWHLL 188
Query: 190 QEIITFRNHLDDKAKQIMDDEGFLTTVIRGFAETFPSYIGRMPVNLTMISKQSWKRAGTR 249
+++I + L I + ++ + P ++++S++ +R GTR
Sbjct: 189 EDLIECKTVLQYMLFDINQGLSYQVAELK---------LKNSPAVVSIMSRRCTRRLGTR 239
Query: 250 FNVRGIDDEANVANFCETEFIMYSEEYCFAVTEIRGSVPVFWEQDTAL-INPKVTITRSV 308
RG + E + ANF E+E I+ + F++ ++RGS+P+ WEQ L P++ I +
Sbjct: 240 MWRRGANLEGDAANFVESEQIVEINGFKFSLLQVRGSIPLLWEQIVDLSYKPRLKINKH- 298
Query: 309 EATQSTFDEHFKRLIQKYGPVHVVNLLSTKSSEIELTRRYREHFERSKSLKLNSEIFLTE 368
E T HF L Q+YG + V+L E L++ Y E+ ++ S
Sbjct: 299 EETPKVVQRHFHDLCQRYGEIMAVDLTDQHGDEGALSKAYATEMEKLPDVRYVS------ 352
Query: 369 FDFHKETKEEGFAAASKIMPTLERSILENGYFSYDVKEKKQLSEQNGVFRTNCLDCLDRT 428
FDFH+ F + + + GYF D E L EQ GV R+NC+DCLDRT
Sbjct: 353 FDFHQVCGTTNFDNLGVLYEQIGDEFEKQGYFLVDADENI-LEEQKGVIRSNCIDCLDRT 411
Query: 429 NLIQQFISRYTFILFLEDFQLIKPKLPLIEEYDWYQKHNNIWADHGDAVSQIYTGTNALK 488
N+ Q F+ + + L L+ + + D Y K IWA+ GD VS Y GT ALK
Sbjct: 412 NVTQSFMGQKSLNLQLQRIGVCDSTECISTFEDDYTKFRTIWAEQGDEVSLQYAGTYALK 471
Query: 489 SSFSRKGKMSFAGALSDATKSVSRMYINNFMDKNKQMNIDALLGRLP-HQHSVELFDPI 546
R GK + GA+ D ++SR Y+NNF D +Q +D + GR HS PI
Sbjct: 472 GDLVRYGKQTMTGAIKDGLSAMSRYYLNNFQDGVRQDALDLISGRYTVGTHSPSQLQPI 530
>7292047 [I] KOG1889 Putative phosphoinositide phosphatase
Length = 592
Score = 176 bits (446), Expect = 2e-43
Identities = 128/425 (30%), Positives = 209/425 (49%), Gaps = 30/425 (7%)
Query: 118 GFPIIPEEEYASSSNQQQQHPCHD--LKKLLSNGSFYYSSDFDLTSLLQ-----SRGLNQ 170
G+ IIP Y +S Q++++ + L++ L FY+S +DLT+ LQ ++ +
Sbjct: 98 GYDIIP---YIPNSFQRKENENYLRLLRQTLDTKFFYFSYRYDLTNSLQRQREVAQSRPE 154
Query: 171 HSLSFDNYQEEYMWNSFLMQEIITFRNHLDDKAKQIMDDEGFLTTVIRGFAETFPSYIGR 230
S ++ ++WN +++++ DK E F ++ GF I
Sbjct: 155 VSGLLQRAEQRFVWNGYVLRQFNC------DKM------EKFQLPLVLGFVSINQVQING 202
Query: 231 MPVNLTMISKQSWKRAGTRFNVRGIDDEANVANFCETEFIMYSEEYCFAVTEIRGSVPVF 290
++I+++S +RAGTR RG D++ +VANF ETE I+ + RGS+P
Sbjct: 203 QTFFWSIITRRSVQRAGTRLFCRGSDEQGHVANFVETEQIVEFNGQLTGFVQTRGSMPFH 262
Query: 291 WEQDTALINPKVTITRSVEATQSTFDEHFKRLIQKYGPVHVVNLLSTKSSEIELTRRYRE 350
W Q L + + + HFK I+ YG VNL+ K +E EL Y
Sbjct: 263 WHQLPNLRYKPRPVLVPGKDHLAACGLHFKEQIRLYGNNVAVNLVDHKGAEGELEATYAR 322
Query: 351 HFERSKSLKLNSEIFLTEFDFHKETKEEGFAAASKIMPTLERSILENG-YFSYDVKEKKQ 409
N ++ FDFH E ++ + + ++ L + G Y +D + K
Sbjct: 323 LVREMG----NPQVRYESFDFHSECRKMRWDRLNILIDRLAHEQDQFGVYHVFD--DGKL 376
Query: 410 LSEQNGVFRTNCLDCLDRTNLIQQFISRYTFILFLEDFQLIKPKLPLIEEYDWYQK-HNN 468
+S Q GVFRTNC+DCLDRTN++Q ++R + L+ ++ + D ++
Sbjct: 377 VSTQTGVFRTNCIDCLDRTNVVQSMLARRSLTAVLQKLGVLHVGQKVEHASDIFESIFKG 436
Query: 469 IWADHGDAVSQIYTGTNALKSSFSRKGKMSFAGALSDATKSVSRMYINNFMDKNKQMNID 528
+WAD+ D VS Y+GT ALK+ F+R GK + +GA+ D S+ R Y+NNF D +Q +ID
Sbjct: 437 VWADNADLVSLQYSGTCALKTDFTRTGKRTKSGAMQDGKNSLMRYYLNNFADGQRQDSID 496
Query: 529 ALLGR 533
LG+
Sbjct: 497 LFLGK 501
>At2g01900 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 417
Score = 169 bits (428), Expect = 2e-41
Identities = 106/326 (32%), Positives = 170/326 (51%), Gaps = 41/326 (12%)
Query: 562 TTTSNIKILCGTFNVNGLTKS--VDLSEWLYPIGKRYLPDIVVLGLQEVIELNASSILNV 619
TT N K+ T+NV G+ +D+ + L + DI VLG QEV+ L AS++L
Sbjct: 53 TTLLNYKVFVSTWNVGGIVPDDGLDMEDLLET--HKTPCDIYVLGFQEVVPLRASNVLGS 110
Query: 620 DTSK-SQFWKDLVHSCLNKH-------------------ENYIMLRAEQMSSLIILFFVK 659
D +K S W L+ LNK +++ + ++QM ++I +V+
Sbjct: 111 DNNKVSTKWNSLIRDALNKRARPHRDEDLSESKGINGISQDFRCIISKQMVGILITVWVR 170
Query: 660 ADKVGNVKRVEGSSKKTGLGGMTGNKGAVAIRFDYGSTSFCFINAHLSAGVNNVEERRSD 719
D ++ S G+ G GNKG+V++RF T+FCF+ +HL++G + +ER+ +
Sbjct: 171 GDLWPYIRYPSVSCVGCGIMGCLGNKGSVSVRFQLHETTFCFVCSHLASGGRDRDERQRN 230
Query: 720 YE--------SITKGISFSRSKRIDHHNSTFWLGDLNYRIELPNEKVRSILSLPDNADLD 771
+ S +G S K+I H+ +LGDLNYRI LP EK R ++ ++ +
Sbjct: 231 SDVNEILARSSFPRGSSLDLPKKILDHDRVIFLGDLNYRISLPEEKTRLLV---ESKKWN 287
Query: 772 KLLEHDQLTSEMASESVFKGFMEPSIQFRPTYKYDHGTD------RYDTSEKARIPSWTD 825
LLE+DQL E+ + +F+G+ E ++F PTYKY +D Y EK R P+W D
Sbjct: 288 ILLENDQLRMEIMNGQIFRGWQEGIVKFAPTYKYVPNSDLYYGCITYKKDEKKRAPAWCD 347
Query: 826 RILYKGENLQPMAYSDAKLNLSDHKP 851
RI++ G L+ Y+ + +SDH+P
Sbjct: 348 RIIWYGNGLKQHEYTRGETKISDHRP 373
>CE17405 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 753
Score = 168 bits (425), Expect = 5e-41
Identities = 114/334 (34%), Positives = 173/334 (51%), Gaps = 38/334 (11%)
Query: 550 VNEELRKQEAQFTTTSNIKILCGTFNVNGLTKSVDLSEWLYPIGKRYLPDIVVLGLQEVI 609
V+E +R+ +F T ++KI TFNVNG + W + + + +GLQE+
Sbjct: 78 VDEVMREWMHKFCTFQDVKICVSTFNVNGRSPLSVFPTW-FSQKPEDIAEFYAVGLQEM- 135
Query: 610 ELNASSILNVDTSKSQFWKDLVHSCL-NKHENYIMLRAEQMSSLIILFFVKADKVGNVKR 668
+L+ + + +T K + W D +H L + ++ + ++ + ++ F + V
Sbjct: 136 DLSVGTYIIDNTKKMEGWVDAIHCSLPGGRTQFNVVGSMRLVGIFVIVFQAVNSKVRVSD 195
Query: 669 VEGSSKKTGLGGMT---GNKGAVAIRFDYGSTSFCFINAHLSAGVNNVEERRSDYESITK 725
V TG+ + GNKG A+ T CF+NAH +AG N +E R D+ I
Sbjct: 196 VNVKYVATGISVLVNKLGNKGGTAVSMKMNDTWVCFVNAHFAAGNNELERRNQDFRDIYN 255
Query: 726 GISF-SRSKR--------------IDHHNSTFWLGDLNYRIE-----LPNEKVRSILSLP 765
+ F RS++ + H+ FW GDLNYR+ + N++VR I S
Sbjct: 256 DMVFYPRSQQEGLRDRPLEVPIMCLYDHDVVFWFGDLNYRLNTDMYGISNDEVRRIASSD 315
Query: 766 DNADLDKLLEHDQLTSEMASESVFKGFMEPS-IQFRPTYKYDHGTDRYDTSEKARIPSWT 824
ADL L+H QL +MA +VFK F EPS + FRPTYKYD GT+ +DTSEK R+P+WT
Sbjct: 316 KFADL---LQHCQLREQMARGTVFKDFEEPSTLPFRPTYKYDCGTNTWDTSEKGRVPAWT 372
Query: 825 DRIL-YKG------ENLQPMAYSDAKLNLSDHKP 851
DRIL +K E+++PM D + +SDHKP
Sbjct: 373 DRILTFKKYPQVGLESIRPMVSIDT-ITISDHKP 405
>SPAC9G1.10c [U] KOG0565 Inositol polyphosphate 5-phosphatase and related proteins
Length = 1191
Score = 162 bits (410), Expect = 3e-39
Identities = 116/384 (30%), Positives = 188/384 (48%), Gaps = 54/384 (14%)
Query: 546 INDYVNEELRKQEAQFTTTSNIKILCGTFNVNGLTKSVDLSE-----WLYP--IGKRYLP 598
+ D++ E+R + +++ +++ IL ++N G +K DL + P I P
Sbjct: 768 MGDWLATEMRSRFPEYSNFTDVSILICSWNA-GASKPSDLDSDTIGASMIPMMIRDNGYP 826
Query: 599 DIVVLGLQEVIELN-----ASSILNVDTSKS------------QFWKDLVHSCL---NKH 638
DIVV G QE+++L A SIL+ +SK + W++ + S + + +
Sbjct: 827 DIVVFGFQELVDLENKRLTARSILSKSSSKGGSSNSANISSQYRLWREKLESEMMRVSSN 886
Query: 639 ENYIMLRAEQMSSLIILFFVKADKVGNVKRVEGSSKKTGLGGMTGNKGAVAIRFDYGSTS 698
++Y +L E + L FVK ++ ++ ++ KTGLGG+ GNKGA+ +RF TS
Sbjct: 887 DDYQVLVCENLVGLFSCVFVKNKLQSKIRMLQSTTVKTGLGGLHGNKGAIVVRFLVDDTS 946
Query: 699 FCFINAHLSAGVNNVEERRSDYESITKGIS-FSRSKRIDH---------------HNSTF 742
+C +N HL+AG +N R +D +I S F + D H
Sbjct: 947 YCIVNCHLAAGQSNKAARNNDLATILDNASLFPENDETDQLNTFVGGGDGSLIMDHEVCV 1006
Query: 743 WLGDLNYRIELPNEKVRSILSLPDNADLDKLLEHDQLTSEMASESVF--KGFMEPSIQFR 800
GDLNYRI K L L D+ LL+ DQL E + F + F EP I F
Sbjct: 1007 LHGDLNYRINTLRPKA---LDLIKKNDIKTLLQSDQLLVERKRNAGFRLRTFTEPEITFA 1063
Query: 801 PTYKYDHGTDRYDTSEKARIPSWTDRILYKG--ENLQPMAYSDAKLNLSDHKPXXXXXXX 858
PTYKYD +++YD+SEK R+P+W DRI Y+G + + Y+ +L SDH+P
Sbjct: 1064 PTYKYDVHSEQYDSSEKKRVPAWCDRICYRGSPDYISAENYTRYELKASDHRPVSALIHS 1123
Query: 859 XXXFIDEESK---IQMTKKLYMDY 879
++ +S+ + K+ +++Y
Sbjct: 1124 KAKMVNAQSQGSTWDVVKRKWIEY 1147
>At3g51460 [I] KOG1889 Putative phosphoinositide phosphatase
Length = 603
Score = 161 bits (407), Expect = 6e-39
Identities = 153/532 (28%), Positives = 230/532 (42%), Gaps = 106/532 (19%)
Query: 60 IHGFIGLIELEGSIFIGTITGKSEVASPIPGETVNKIYGVDFFCLDSNRWDFVEFDSNGF 119
I G +G+++L ++ +T V S + G + K+
Sbjct: 65 IFGVVGMLKLLAGSYLVVVTESERVGSFL-GHPIFKV--------------------TTL 103
Query: 120 PIIPEEEYASSSNQQQQHPCHDLKKLLS----NGSFYYSSDFDLT---SLLQSRGLNQHS 172
++P + +S ++Q+ + KLLS Y+S + +LT L G S
Sbjct: 104 KVLPCDHSLKNSPEEQKKMETEFSKLLSVAEKTTGLYFSYEVNLTLSSQRLHEMGDESKS 163
Query: 173 LSFDNYQE-EYMWNSFLMQEIITFRNHLDDKAKQIMDDEGFLTTVIRGFA---ETFPSYI 228
L E ++WN+++++ +I D+K Q FL VI+G + F + I
Sbjct: 164 LPLWRQAEPRFLWNNYMLEVLI------DNKLDQ------FLLPVIQGNILCYQFFETAI 211
Query: 229 GRMPVNLTMISKQSWKR------------------------------AGTRFNVRGIDDE 258
GR V++T+I+++ +R GTR RG D +
Sbjct: 212 GRDIVDITLIARRCTRRNERYMSLPAGNLNAEYCVVNVSSPLSWIVLQGTRMWRRGADLD 271
Query: 259 ANVANFCETEFIMYSEEYCFAVTEIRGSVPVFWEQDTAL-INPKVTITRSVEATQSTFDE 317
VANF ETE I+ Y + ++RGS+P WEQ L PK I + EA + +
Sbjct: 272 GYVANFVETEQIVQMNGYTSSFVQVRGSMPFMWEQVVDLTYKPKFEIVQPEEAKRIA-ER 330
Query: 318 HFKRLIQKYGPVHVVNLLSTKSSEIELTRRYREHFERSKSLKLNSEIFLTEFDFHKETKE 377
HF L +KYG V V+L++ + E L +Y + +I FDFH+
Sbjct: 331 HFLDLRKKYGSVLAVDLVNKQGGEGRLCEKYATVMQHI----TGDDIRYLHFDFHQICGH 386
Query: 378 EGFAAASKIMPTLERSILENGYFSYDVKEKKQLSEQNGVFRTNCLDCLDRTNLIQ----- 432
F S + +E + +NGYF + K +K + EQ GV R+NC+DCLDRTN+ Q
Sbjct: 387 IHFERLSILYEQIEGFLEKNGYFLLNEKGEK-MKEQLGVVRSNCIDCLDRTNVTQVSHKK 445
Query: 433 ---QFISRYTFILFLEDFQLIKPKLPLIEEYDWYQKHNNIWADHGDAVSQIYTGTNALKS 489
Q IS + ++ F LP E K IWA+HGD +S Y+GT ALK
Sbjct: 446 TMMQLISYWPLLIHAAYF------LPNAEHD--RSKDVRIWANHGDEISIQYSGTPALKG 497
Query: 490 SFSR---------KGKMSFAGALSDATKSVSRMYINNFMDKNKQMNIDALLG 532
F R G + G L D S+ R Y+NNF D KQ ID L G
Sbjct: 498 DFVRYFCHMFNLGYGHRTAHGVLKDGWSSLRRYYLNNFADGTKQDAIDLLQG 549
>Hs9845291 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 644
Score = 154 bits (388), Expect = 1e-36
Identities = 98/310 (31%), Positives = 150/310 (47%), Gaps = 31/310 (10%)
Query: 559 AQFTTTSNIKILCGTFNVNGLTK-SVDLSEWLYPIGKRYLPDIVVLGLQEVIELNASSIL 617
A++ N+ + T+N+ G + L E+L P Y D+ V+G+QE
Sbjct: 291 ARYFPDRNVALFVATWNMQGQKELPPSLDEFLLPAEADYAQDLYVIGVQE---------- 340
Query: 618 NVDTSKSQFWKDLVHSCLNKHENYIMLRAEQMSSLIILFFVKADKVGNVKRVEGSSKKTG 677
S ++ W+ + L H Y++L + L + F++ D + VE S+ T
Sbjct: 341 --GCSDTREWETRLQETLGPH--YVLLSSAAHGVLYMSLFIRRDLIWFCSEVECSTVTTR 396
Query: 678 LGGMTGNKGAVAIRFDYGSTSFCFINAHLSAGVNNVEERRSDYESITKGISFSR------ 731
+ KGA+ I F + TSF FI +H ++G V ER DY + + R
Sbjct: 397 IVSQIKTKGALGISFTFFGTSFLFITSHFTSGDGKVAERLLDYTRTVQALVLPRNVPDTN 456
Query: 732 ---SKRID---HHNSTFWLGDLNYRIELPNEKVRSILSLPDNADLDKLLEHDQLTSEMAS 785
S D + FW GD N+R+ V ++L D+ LL+HDQL EM
Sbjct: 457 PYRSSAADVTTRFDEVFWFGDFNFRLSGGRTVVDALLCQGLVVDVPALLQHDQLIREMRK 516
Query: 786 ESVFKGFMEPSIQFRPTYKYDHGTDRYDTSEKARIPSWTDRILYKGE---NLQPMAYSDA 842
S+FKGF EP I F P+YK+D G D YD++ K R PS+TDR+LY+ ++ P++YS
Sbjct: 517 GSIFKGFQEPDIHFLPSYKFDIGKDTYDSTSKQRTPSYTDRVLYRSRHKGDICPVSYSSC 576
Query: 843 K-LNLSDHKP 851
+ SDH+P
Sbjct: 577 PGIKTSDHRP 586
>At2g37440 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 401
Score = 153 bits (386), Expect = 2e-36
Identities = 105/338 (31%), Positives = 158/338 (46%), Gaps = 57/338 (16%)
Query: 567 IKILCGTFNVNGLT--KSVDLSEWL--------YPIGKRYLP--------DIVVLGLQEV 608
I++ GT+NV G + + +DL +WL Y +G Y +I+ L QE+
Sbjct: 2 IRMFVGTWNVGGKSPHEGLDLKDWLKSPADADIYVLGYAYNHINWFYRTFNILFLEFQEI 61
Query: 609 IELNASSILNV-DTSKSQFWKDLVHSCLNKHEN---------------------YIMLRA 646
+ LNA ++L D + W L+ LN N Y + +
Sbjct: 62 VPLNAGNVLGAEDNGPAAKWLSLIREALNNTNNLSFSGLSDDTPIPCNSTPPRGYSLAAS 121
Query: 647 EQMSSLIILFFVKADKVGNVKRVEGSSKKTGLGGMTGNKGAVAIRFDYGSTSFCFINAHL 706
+QM + + +V+ D + ++ S G+ G GNKG+V+I TS CF+ HL
Sbjct: 122 KQMVGIFLCVWVRDDLRKRITNLKVSCVGRGIMGYLGNKGSVSISMSLHETSLCFVCTHL 181
Query: 707 SAGVNNVEE--RRSDYESITKGISFSRSKR------IDHHNSTFWLGDLNYRIELPNEKV 758
++G +E R D I K FSRS + I H+ WLGDLNYR+ ++
Sbjct: 182 TSGEKEGDELRRNLDVTEIFKRTRFSRSSKDSRPETIMDHDKVIWLGDLNYRLRASSDLH 241
Query: 759 RSILSLPDNADLDKLLEHDQLTSEMASESVFKGFMEPSIQFRPTYKYDHGTDRY-----D 813
+ N D + LLE DQL E + +FKG+ E I F PTYKY +D Y
Sbjct: 242 EQL----RNHDWESLLEKDQLKIEQRAGRIFKGWEEGKIYFAPTYKYRINSDNYVVQTEK 297
Query: 814 TSEKARIPSWTDRILYKGENLQPMAYSDAKLNLSDHKP 851
+ EK R P+W DRIL+KG+ ++ + Y + SDH+P
Sbjct: 298 SKEKRRTPAWCDRILWKGDGMKQLWYVRGESKFSDHRP 335
>7294594 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 747
Score = 147 bits (370), Expect = 1e-34
Identities = 92/283 (32%), Positives = 141/283 (49%), Gaps = 29/283 (10%)
Query: 567 IKILCGTFNVNGLTKSVDLSEWLYPIGKRYLPDIVVLGLQEVIELNASSILNVDTSKSQF 626
I + GT+N+NG + L++++ P ++PDIVV+G QE T
Sbjct: 391 ITVFVGTWNMNGHSPPKQLNDFVLPANVEHVPDIVVMGTQE------------STPDRFE 438
Query: 627 WKDLVHSCLNKHENYIMLRAEQMSSLIILFFVKADKVGNVKRVEGSSKKTGLGGMTGNKG 686
W+ + L ++++ A + +L + +++ D + E +S G KG
Sbjct: 439 WEVTIQETLGP--SHVLFHATTLGTLHLAVYMRRDLIWYCSVPEDASMSVRTGSAFRTKG 496
Query: 687 AVAIRFDYGSTSFCFINAHLSAGVNNVEERRSDYESITKGISFSRSKRIDHH-------- 738
AVAI F TS F+ +HL+A V+ER SD + I + R+ H
Sbjct: 497 AVAISFCLFGTSMLFVTSHLTAHQQKVKERVSDVKRIINALDLPRNLPNQRHKNKDVTQN 556
Query: 739 -NSTFWLGDLNYRIELPNEKVRSILS-----LPDNADLDKLLEHDQLTSEMASESVFKGF 792
++ FW GDLN+R+ P EK+ + LP + + DQLTS +A + F+GF
Sbjct: 557 FDNVFWCGDLNFRLGEPREKLLEWIQNTKFPLPSHLP-HGYMHTDQLTSVLADGAAFRGF 615
Query: 793 MEPSIQFRPTYKYDHGTDRYDTSEKARIPSWTDRILYKGENLQ 835
ME +I F PTYKYD G+ +DTS K R P++TDRILYK +Q
Sbjct: 616 MEANITFPPTYKYDPGSQNFDTSSKQRAPAYTDRILYKYRQMQ 658
>ECU08g1420 [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (synaptojanin)
INP51/INP52/INP53 family
Length = 453
Score = 145 bits (366), Expect = 3e-34
Identities = 101/299 (33%), Positives = 150/299 (49%), Gaps = 39/299 (13%)
Query: 234 NLTMISKQSWKRAGTRFNVRGIDDEANVANFCETEF-IMYSEEYCFAVTEIRGSVPVFWE 292
++ ++S S R GTR+ RGID+E N + F +T F + F T IRGSVP+FW
Sbjct: 180 HMKLLSLVSSNRVGTRYLCRGIDEEGNASLFVKTHFQTKRNNSTIFDFTIIRGSVPIFWS 239
Query: 293 QDTALINPKVTITRSVEATQSTFDEHFKRLIQKYGPVHVVNLLSTKSSEIELTRRYREHF 352
Q I KV I A + F +HFK+L ++YG ++V+NLL K E +LT HF
Sbjct: 240 QRGHGIPAKVNIYGEDGAVKKAFAKHFKKLRREYGKIYVINLLGEKKYEKQLT----SHF 295
Query: 353 ERSKSLKLNSEIFLTEFDFHKETKEEGFAAASKIMPTLERSILENGYFSYDVKEKKQLSE 412
R L+ I T FD + A + L+ + YF + + + +
Sbjct: 296 SRLLDLE---NIPYTTFDLN---------AHASNYDDLKFLL----YF-----KLQGIGQ 334
Query: 413 QNGVFRTNCLDCLDRTNLIQQFISRYTFILFLEDFQLIKPKLPLIEEYDWYQKHNNIWAD 472
Q+ VFR NCLDCLDRTN+ Q I + F + D +K + WAD
Sbjct: 335 QDIVFRVNCLDCLDRTNVAQSLICMFYFEKVVCDGNALK-------------RMQECWAD 381
Query: 473 HGDAVSQIYTGTNALKSSFSRKGKMSFAGALSDATKSVSRMYINNFMDKNKQMNIDALL 531
+G+++S +YTG++A+K + KG+ SF G + D S +R+ F D+ K I+ LL
Sbjct: 382 NGNSLSNLYTGSDAMKRELALKGRRSFVGYMDDFVISATRLINGRFTDRQKHSIINVLL 440
>At1g47510 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 331
Score = 144 bits (364), Expect = 6e-34
Identities = 104/300 (34%), Positives = 155/300 (51%), Gaps = 34/300 (11%)
Query: 561 FTTTSNIKILCGTFNVNGLTKSVDLSEWLYPIGKRYLPDIVVLGLQEVIELNASSILNVD 620
F+ +++ I T+N+NG DL E +GK D++V+GLQE + N +L
Sbjct: 45 FSRKADLCIRIITWNMNGNVSYEDLVEL---VGKERKFDLLVVGLQEAPKANVDQLLQTA 101
Query: 621 TSKSQFWKDLVHSCLNKHENYIMLRAEQMSSLIILFFVKADKVGNVKRVEGSSKKTG-LG 679
+S + HE +L ++ S+ + F + VK ++ G G
Sbjct: 102 SSPT-------------HE---LLGKAKLQSVQLYLFGPKNSHTLVKELKAERYSVGGCG 145
Query: 680 GMTGNK-GAVAIRFDYGSTSFCFINAHLSAGVNNVEERRSDYESITKGISFSRSKRIDHH 738
G+ G K GAVAIR +Y FI+ HLSA V++R ++ I + R KR
Sbjct: 146 GLIGRKKGAVAIRINYDDIKMVFISCHLSAHAKKVDQRNTELRHIANSL-LPRDKR--KR 202
Query: 739 NSTFWLGDLNYRIE-LPNEKVRSILSLPDNADLDKLLEHDQLTSEMASESVFKGFMEPSI 797
+ T WLGDLNYRI+ + N VRS++ N L+ DQL E +FKG+ E ++
Sbjct: 203 DLTVWLGDLNYRIQDVSNHPVRSLIQ---NHLQSVLVSKDQLLQEAERGEIFKGYSEGTL 259
Query: 798 QFRPTYKYDHGTDRYDTSEKARIPSWTDRILYK---GENLQPMAYSDAKLNL---SDHKP 851
F+PTYKY+ G+ YDTS K R+P+WTDRIL+K +N+Q +S ++ SDHKP
Sbjct: 260 GFKPTYKYNVGSSDYDTSHKIRVPAWTDRILFKIQDTDNIQATLHSYDSIDQVYGSDHKP 319
>At2g32010 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 501
Score = 144 bits (363), Expect = 8e-34
Identities = 85/218 (38%), Positives = 118/218 (53%), Gaps = 10/218 (4%)
Query: 641 YIMLRAEQMSSLIILFFVKADKVGNVKRVEGSSKKTGLGGMTGNKGAVAIRFDYGSTSFC 700
Y ++ ++QM + + +VK++ +VK ++ S GL G GNKG+++I TSFC
Sbjct: 242 YCLVASKQMVGIFLTIWVKSELREHVKNMKVSCVGRGLMGYLGNKGSISISMLLHQTSFC 301
Query: 701 FINAHLSAGVNNVEE--RRSDYESITKGISFSRSKRIDHHNSTFWLGDLNYRIELPNEKV 758
F+ HL++G +E R SD I K F R + N WLGDLNYRI L
Sbjct: 302 FVCTHLTSGQKEGDELRRNSDVMEILKKTRFPRVQSSADENRVIWLGDLNYRIAL---SY 358
Query: 759 RSILSLPDNADLDKLLEHDQLTSEMASESVFKGFMEPSIQFRPTYKYDHGTDRY-----D 813
RS +L + + LLE+DQL E VFKG+ E I F PTYKY + +DRY
Sbjct: 359 RSAKALVEMQNWRALLENDQLRIEQKRGHVFKGWNEGKIYFPPTYKYSNNSDRYAGGDLH 418
Query: 814 TSEKARIPSWTDRILYKGENLQPMAYSDAKLNLSDHKP 851
EK R P+W DRIL+ GE L ++Y + SDH+P
Sbjct: 419 PKEKRRTPAWCDRILWHGEGLHQLSYVRGESRFSDHRP 456
>At5g04980 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 366
Score = 140 bits (354), Expect = 8e-33
Identities = 84/228 (36%), Positives = 123/228 (53%), Gaps = 20/228 (8%)
Query: 641 YIMLRAEQMSSLIILFFVKADKVGNVKRVEGSSKKTGLGGMTGNKGAVAIRFDYGSTSFC 700
Y ++ ++QM + + +++ + + +V + SS G+ G GNKG +A+ TSFC
Sbjct: 121 YGLVASKQMVGIFLTVWMRKELIQHVSHLRISSVTRGIMGCLGNKGCIAVSLQLYKTSFC 180
Query: 701 FINAHLSAGVNNVEERRS--DYESITKGISFSR---------SKRIDHHNSTFWLGDLNY 749
FI +HL++G +ERR D I K SF R RI H+ WLGDLNY
Sbjct: 181 FICSHLASGEREGDERRRNLDVIEILKNTSFPRICRTSFTRVPDRITKHDRVIWLGDLNY 240
Query: 750 RIELPNEKVRSILSLPDNADLDKLLEHDQLTSEMASESVFKGFMEPSIQFRPTYKYDHGT 809
RI L + +++L D D LL DQL E + VFKG+ E I F PTYKY + +
Sbjct: 241 RIALSYSETKTLL---DKNAWDTLLNKDQLKIERDAGRVFKGWHEGKIFFAPTYKYSYNS 297
Query: 810 DRY--DTSE----KARIPSWTDRILYKGENLQPMAYSDAKLNLSDHKP 851
D Y DTS+ K R P+W DRIL+ G+ ++ ++Y + SDH+P
Sbjct: 298 DAYAGDTSKEKKNKRRTPAWCDRILWHGDGIRQLSYVRGESRFSDHRP 345
>At1g05470 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 585
Score = 140 bits (353), Expect = 1e-32
Identities = 87/227 (38%), Positives = 119/227 (52%), Gaps = 19/227 (8%)
Query: 641 YIMLRAEQMSSLIILFFVKADKVGNVKRVEGSSKKTGLGGMTGNKGAVAIRFDYGSTSFC 700
Y ++ ++QM + + +VK++ +VK ++ S GL G GNKG+++I TSFC
Sbjct: 317 YCLVASKQMVGVFLTIWVKSELREHVKNMKVSCVGRGLMGYLGNKGSISISMLLHQTSFC 376
Query: 701 FINAHLSAGVNNVEE--RRSDYESITKGISFSRSK---------RIDHHNSTFWLGDLNY 749
F+ HL++G +E R SD I K F R K I H+ WLGDLNY
Sbjct: 377 FVCTHLTSGQKEGDELKRNSDVMEILKKTRFPRVKSSEEEKSPENILQHDRVIWLGDLNY 436
Query: 750 RIELPNEKVRSILSLPDNADLDKLLEHDQLTSEMASESVFKGFMEPSIQFRPTYKYDHGT 809
RI L RS +L + + LLE+DQL E VFKG+ E I F PTYKY +
Sbjct: 437 RIAL---SYRSAKALVEMQNWRALLENDQLRIEQKRGHVFKGWNEGKIYFPPTYKYSRNS 493
Query: 810 DRYD-----TSEKARIPSWTDRILYKGENLQPMAYSDAKLNLSDHKP 851
DRY EK R P+W DRIL+ GE L ++Y + SDH+P
Sbjct: 494 DRYSGDDLHPKEKRRTPAWCDRILWFGEGLHQLSYVRGESRFSDHRP 540
>CE08566 [I] KOG1888 Putative phosphoinositide phosphatase
Length = 921
Score = 137 bits (346), Expect = 7e-32
Identities = 131/535 (24%), Positives = 238/535 (44%), Gaps = 86/535 (16%)
Query: 121 IIPEEEYASSSNQQQQHPCHDLKKLLSNGSFYYSSDFDLTSLLQSRGL----NQHSLSFD 176
+IP S++ ++Q + + + FY+S +D++ Q L N H
Sbjct: 130 MIPIAMDGVSTSSEEQKYVKLFQSVDLSTDFYFSYSYDMSRTFQENSLRSDWNNHGQRRL 189
Query: 177 NYQEEYMWNSFLMQEIITFRNHLDDKAKQIMDDEGFLTTVIRGFAETFPSYIGRMPVNLT 236
E ++WNSFL++ + ++ + E + ++ G+ ++ ++LT
Sbjct: 190 EADERFVWNSFLLEPL-----------RKNLISERWFVEIVHGYVRQEYIFLPIGRISLT 238
Query: 237 MISKQSWKRAGTRFNVRGIDDEANVANFCETEFIMY--------SEEYCFAVTEIRGSVP 288
+I ++S K AGTRF RG + NVAN+ ETE I++ ++ + ++RGSVP
Sbjct: 239 IIGRRSTKYAGTRFLKRGANPTGNVANYVETEQIVWDMASSGNVADGRFSSFVQMRGSVP 298
Query: 289 VFWEQDTA---LINPKVTITRSVEATQSTFDEHFKRLIQKYG-PVHVVNLL---STKSSE 341
+ W QD + ++ + + + E T HF+ + KYG P+ ++NL+ + E
Sbjct: 299 MRWSQDPSTRGVVGKPLILIDNHEPHAQTAASHFRDVRNKYGNPIVIMNLIKRNEKRRHE 358
Query: 342 IELTRRYREHFERSKSLKLNSE-IFLTEFDFHKETKEEGFAAASKIMPTLE----RSILE 396
L ++ ++ E N E + FD + K + ++ +E +SIL+
Sbjct: 359 GVLHTQFLKNIEYLNQFLPNEEKLCYISFDVARCNKAANSMPSINVLNVMEDLSMKSILK 418
Query: 397 NGYF-SYDVKEKKQLSE-------------------QNGVFRTNCLDCLDRTNLIQQFIS 436
NG+F S+ + E ++ Q+G+ RTNC+DCLDRTN+ Q I+
Sbjct: 419 NGWFQSFPLSEALKIRPREAFATLDAHHSKDGRFMIQHGICRTNCVDCLDRTNVAQFVIA 478
Query: 437 RYTFILFLEDFQLI-KPKLPLIEEYDWYQKHNNIWADHGDAVSQIYTGTNALKSSFSRKG 495
+ L ++ +P L L E + +++ +HGD ++ Y G+ + S + K
Sbjct: 479 KVALGCQLCAMGILDEPNLTLQSEV--CRLLEDMFDEHGDTMALQYAGSQLVHSIKTYKK 536
Query: 496 KMSFAGALSDATKSVSRMYINNFMDKNKQMNIDALLGRLPHQHSVELFDPINDYVNEELR 555
+F D +++SR Y N F D +KQM I+ LG +F P
Sbjct: 537 TAAFQERRRDVFQTLSRYYSNTFNDWDKQMAINLFLG---------VFRP---------- 577
Query: 556 KQEAQFTTTSNIKILCGTFNVN---GLTKSVDLSEWLYPIGKRYLPDIVVLGLQE 607
+ TT N+ L +N++ L + D W + ++ L D+V L E
Sbjct: 578 ----RITTMKNLWDLTSDYNLHFPYSLKINTDYCAW--TLSEKELEDLVFLDYDE 626
>At1g71710 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 655
Score = 137 bits (345), Expect = 9e-32
Identities = 79/222 (35%), Positives = 114/222 (50%), Gaps = 14/222 (6%)
Query: 641 YIMLRAEQMSSLIILFFVKADKVGNVKRVEGSSKKTGLGGMTGNKGAVAIRFDYGSTSFC 700
Y+ L ++QM +++ +VK +++ V S+ G+ G GNKGAV++ T FC
Sbjct: 399 YVRLVSKQMVGILLTIWVKRSLRKHIQNVRVSTVGVGVMGYIGNKGAVSVSMSINQTFFC 458
Query: 701 FINAHLSAGVNNVEE--RRSDYESITKGISF------SRSKRIDHHNSTFWLGDLNYRIE 752
FIN HL+AG V++ R +D I K F K I H WLGDLNYR+
Sbjct: 459 FINTHLTAGEREVDQIKRNADVHEIHKRTVFHSVSALGLPKLIYDHERIIWLGDLNYRLS 518
Query: 753 LPNEKVRSILSLPDNADLDKLLEHDQLTSEMASESVFKGFMEPSIQFRPTYKYDHGTDRY 812
EK R ++S + KLLE+DQL E F G+ E ++ F PTYKY +D Y
Sbjct: 519 SSYEKTRDLIS---KREWSKLLEYDQLVKEYRKGRAFDGWSEGTLHFPPTYKYQANSDEY 575
Query: 813 ---DTSEKARIPSWTDRILYKGENLQPMAYSDAKLNLSDHKP 851
D R P+W DR+L G+ ++ + Y + SDH+P
Sbjct: 576 TANDGKAPKRTPAWCDRVLSYGKGMRLVHYRRTEQKFSDHRP 617
>7293245 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 508
Score = 137 bits (344), Expect = 1e-31
Identities = 89/270 (32%), Positives = 136/270 (49%), Gaps = 20/270 (7%)
Query: 596 YLPDIVVLGLQEVIELNASSILNVDTSKSQFWKDLVHSCLNKHENYIMLRAEQMSSLIIL 655
+LPDI LGLQEV +L + K W L ++ Y+ ++ EQM L++
Sbjct: 71 HLPDIYALGLQEVNAQPQQQVLGL--FKEDPWTHKAKELLRNYD-YVAVKTEQMQGLLLS 127
Query: 656 FFVKADKVGNVKRVEGSSKKTGLGGMTGNKGAVAIRFDYGSTSFCFINAHLSAGVNNVEE 715
FV+ V +++ +E +TG GG+ GNKGAV++RF F+ AHL+A + ++E
Sbjct: 128 MFVRRQHVEHLQDIEAEFTRTGFGGIWGNKGAVSVRFTLYGCGLAFVVAHLTAHDHMMDE 187
Query: 716 RRSDYESITKGISF--SRSKRIDHHNSTFWLGDLNYRIELPNEKVRSILSLPDNADLDKL 773
R DY+ I + + R + I H+ FW GDLN+R++ + + D + + L
Sbjct: 188 RIEDYKQILENHHYHVKRYREIYDHDYVFWFGDLNFRLQGSDSSTEVRELVRDESQHEAL 247
Query: 774 LEHDQLTS-EMASESVFKGFMEPSIQFRPTYKYDHGTDRYDTSEKARIPSWTDRILYKGE 832
++ DQL S+ F+ E F PT+K+ GT YD R P+WTDRI+Y +
Sbjct: 248 IQRDQLYQVREKSQLAFQVLQERLPAFPPTFKFREGTSEYDLK---RRPAWTDRIMYAVQ 304
Query: 833 --NLQP--------MAYSDAKL-NLSDHKP 851
N QP +Y L +SDHKP
Sbjct: 305 PLNRQPGMQLSIEQCSYKSHPLYTISDHKP 334
>At2g43900 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 1305
Score = 135 bits (340), Expect = 3e-31
Identities = 106/372 (28%), Positives = 172/372 (45%), Gaps = 74/372 (19%)
Query: 545 PINDYVNEELRKQEAQFTTTSNIKILCGTFNVNGLTKSVD-LSEWLYPIGKRYLPDIVVL 603
P++ + EL ++E + T +++IL G++NV S D L WL + I+V+
Sbjct: 554 PLDGIIRSELAEKERTYAQTDSVRILTGSWNVGQGKASHDALMSWLGSVASDV--GILVV 611
Query: 604 GLQEVIELNASSIL----------NVDTSKSQFWKDLVHSCLNKHENYIMLRAEQMSSLI 653
GLQEV E+ A + N ++ Q+W D + L++ + + + Q++ L+
Sbjct: 612 GLQEV-EMGAGFLAMSAAKESVGGNEGSTIGQYWIDTIGKTLDEKAVFERMGSRQLAGLL 670
Query: 654 ILFFVKADKVGNVKRVEGSSKKTGLGGMTGNKGAVAIRFDYGSTSFCFINAHLSAGVNNV 713
I +V+ + +V ++ ++ G G GNKG V +R CFIN HL+A + V
Sbjct: 671 ISLWVRKNLRTHVGDIDVAAVPCGFGRAIGNKGGVGLRIRVFDRIMCFINCHLAAHLEAV 730
Query: 714 EERRSDYESITKGISFSRSKRIDHHNS--------------------------------- 740
R +D++ I K +SF+RS + HN+
Sbjct: 731 NRRNADFDHIYKTMSFTRSS--NAHNAPAAGVSTGSHTTKSANNANVNTEETKQDLAEAD 788
Query: 741 -TFWLGDLNYRI-ELPNEKVRSILSLPDNADLDKLLEHDQLTSEMASESVFKGFMEPSIQ 798
+ GD NYR+ + ++ R +S D L E DQL +EM + VF+G E I
Sbjct: 789 MVVFFGDFNYRLFGISYDEARDFVS---QRSFDWLREKDQLRAEMKAGRVFQGMREAIIT 845
Query: 799 FRPTYKYDH---GTDRYDTSEKARIPSWTDRILYKGENLQP--------------MAYSD 841
F PTYK++ G YD+ EK RIP+W DR++++ P M Y D
Sbjct: 846 FPPTYKFERHRPGLGGYDSGEKKRIPAWCDRVIFRDTRTSPESECSLDCPVVASIMLY-D 904
Query: 842 AKLNL--SDHKP 851
A +++ SDHKP
Sbjct: 905 ACMDVTESDHKP 916
>At5g65090 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 569
Score = 134 bits (338), Expect = 6e-31
Identities = 79/238 (33%), Positives = 122/238 (51%), Gaps = 29/238 (12%)
Query: 640 NYIMLRAEQMSSLIILFFVKADKVGNVKRVEGSSKKTGLGGMTGNKGAVAIRFDYGSTSF 699
+Y ++ ++QM L + + + + + ++ + S G+ G GNKG +AI TSF
Sbjct: 291 SYRLIASKQMVGLFLSVWARRELIPHISHLRLDSVGRGIMGRLGNKGCIAISMSLHQTSF 350
Query: 700 CFINAHLSAGVNNVEERR-----------SDYESITKGISFSRSKRIDHHNSTFWLGDLN 748
CF+ +HL++G +E R + + +TK + +RI H+ WLGDLN
Sbjct: 351 CFVCSHLASGEKEGDELRRNADVAEILKHTQFPKLTKNPNCHAPERIIDHDRVLWLGDLN 410
Query: 749 YRIELPNEKVRSILSLPDNADLDKLLEHDQLTSEMASESVFKGFMEPSIQFRPTYKYDHG 808
YR+ L E+ R +L ++ D D LLE DQL E + VF GF E I F PTYKY
Sbjct: 411 YRVALTYEETRVLL---EDNDWDTLLERDQLNMERGAGRVFSGFQEGQIFFAPTYKYSQN 467
Query: 809 TDRY-----DTSEKARIPS------WT----DRILYKGENLQPMAYSDAKLNLSDHKP 851
+D Y + +K R P+ W DRIL+KGE ++ ++Y + SDH+P
Sbjct: 468 SDAYAGEMTKSKKKRRTPACVIVWIWNVCRCDRILWKGEGIEQLSYIRGESRFSDHRP 525
>At3g63240 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 574
Score = 134 bits (338), Expect = 6e-31
Identities = 81/227 (35%), Positives = 118/227 (51%), Gaps = 19/227 (8%)
Query: 641 YIMLRAEQMSSLIILFFVKADKVGNVKRVEGSSKKTGLGGMTGNKGAVAIRFDYGSTSFC 700
Y ++ ++QM + + +VK+D +V ++ S GL G GNKG+++I TSFC
Sbjct: 278 YCLVASKQMVGIFLTVWVKSDLRDSVNNLKVSCVGRGLMGYLGNKGSISISMSVHQTSFC 337
Query: 701 FINAHLSAGVNNVEE--RRSDYESITKGISFSR---------SKRIDHHNSTFWLGDLNY 749
F+ +HL++G +E R SD I + F R + I H+ WLGDLNY
Sbjct: 338 FVCSHLTSGQKEGDELRRNSDVLEILRKTRFPRVNNAGDDKSPQMISEHDRVIWLGDLNY 397
Query: 750 RIELPNEKVRSILSLPDNADLDKLLEHDQLTSEMASESVFKGFMEPSIQFRPTYKYDHGT 809
RI L RS +L + D LLE DQL E VF+G+ E +I F PTYKY + +
Sbjct: 398 RIAL---SYRSAKALVEMRDWRALLEKDQLRIEQRKGCVFEGWKEGTIYFPPTYKYSNNS 454
Query: 810 DRYDTSE-----KARIPSWTDRILYKGENLQPMAYSDAKLNLSDHKP 851
D Y + K R P+W DRIL+ G + ++Y + SDH+P
Sbjct: 455 DIYAGDDRLPKAKRRTPAWCDRILWHGSGISQLSYVRGESRFSDHRP 501
>At1g05630 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 1136
Score = 134 bits (337), Expect = 8e-31
Identities = 104/393 (26%), Positives = 171/393 (43%), Gaps = 69/393 (17%)
Query: 545 PINDYVNEELRKQEAQFTTTSNIKILCGTFNVNGLTKSVD-LSEWLYPIGKRYLPDIVVL 603
P+++ + EL ++E + N++IL GT+NV S D L WL + IV +
Sbjct: 549 PLDNIIRTELSQKETLYARQDNVRILIGTWNVGQGRASHDALMSWLGSVTSDV--GIVAV 606
Query: 604 GLQEVIELNASSILNVDTSKS----------QFWKDLVHSCLNKHENYIMLRAEQMSSLI 653
GLQEV E+ A L + +K Q+W D + L++ + + + Q++ L+
Sbjct: 607 GLQEV-EMGAG-FLAMSAAKETVGLEGSAVGQWWIDAIGKALDEKNTFERMGSRQLAGLL 664
Query: 654 ILFFVKADKVGNVKRVEGSSKKTGLGGMTGNKGAVAIRFDYGSTSFCFINAHLSAGVNNV 713
I + + D +V ++ ++ G G GNKG V +R CF+N HL+A + V
Sbjct: 665 ISLWARKDIRTHVGDLDVAAVPCGFGRAIGNKGGVGLRIRVYDRIMCFVNCHLAAHLEAV 724
Query: 714 EERRSDYESITKGISFSRSKRIDH--------------------------------HNST 741
R +D+ I + + FSR + + + +
Sbjct: 725 NRRNADFNHIFRLMVFSRGQNLSNAAAAGVSTSAYTTKSNTIPSTGAEEIKSDLAAADMV 784
Query: 742 FWLGDLNYRI-ELPNEKVRSILSLPDNADLDKLLEHDQLTSEMASESVFKGFMEPSIQFR 800
+ GD NYR+ + ++ R +S D L E DQL +EM VF+G E I F
Sbjct: 785 AFFGDFNYRLFGITYDEARDFIS---QRSFDWLRERDQLRAEMKVGKVFQGMREALITFP 841
Query: 801 PTYKYDH---GTDRYDTSEKARIPSWTDRILYKGENLQPMAYSDAK-------------- 843
PTYK++ G YD+ EK RIP+W DR++Y+ P + S+ +
Sbjct: 842 PTYKFERNRSGLGGYDSGEKKRIPAWCDRVIYRDTQSSPFSESNLQCPVVSSVIMYEACM 901
Query: 844 -LNLSDHKPXXXXXXXXXXFIDEESKIQMTKKL 875
+ SDHKP +D+ + Q K+
Sbjct: 902 DVTESDHKPVRCKFHATIAHVDKSVRRQELGKI 934
>At2g31830 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 1144
Score = 132 bits (333), Expect = 2e-30
Identities = 113/424 (26%), Positives = 184/424 (42%), Gaps = 82/424 (19%)
Query: 545 PINDYVNEELRKQEAQFTTTSNIKILCGTFNVN-GLTKSVDLSEWLYPIGKRYLPDIVVL 603
P++ + EL ++E + ++KIL GT+NV G L WL IV +
Sbjct: 558 PLDSLIRTELSQKEMAYARQDSVKILIGTWNVGEGRASRGALVSWLGSAVSDV--GIVAI 615
Query: 604 GLQEVIELNASSILNVDTSKS----------QFWKDLVHSCLNKHENYIMLRAEQMSSLI 653
GLQEV ++ A L + T+K Q+W D + + L++ + + + Q++ L+
Sbjct: 616 GLQEV-DMGAG-FLAMSTAKETVGVEGSAVGQWWLDAIGNALDERNTFERMGSRQLAGLL 673
Query: 654 ILFFVKADKVGNVKRVEGSSKKTGLGGMTGNKGAVAIRFDYGSTSFCFINAHLSAGVNNV 713
I +V+ +V ++ ++ G G GNKG V +R CF+N HL+A + V
Sbjct: 674 ISLWVRKSIRTHVGDLDVAAVPCGFGRAIGNKGGVGLRIRVYDRIMCFVNCHLAAHLEAV 733
Query: 714 EERRSDYESITKGISFSRSKRI-------------------DHHNST------------- 741
R +D+ I + + FS+ + + + +NST
Sbjct: 734 TRRNADFNHIYRSMVFSKGQSVYTAAAAGASTSAQALKNNPNTNNSTEEEKSHLASADLV 793
Query: 742 FWLGDLNYRI-ELPNEKVRSILSLPDNADLDKLLEHDQLTSEMASESVFKGFMEPSIQFR 800
+ GD NYR+ + ++ R +S + D L E DQL EM VF+G E I F
Sbjct: 794 AFFGDFNYRLFGITYDEARDFIS---HRSFDWLREKDQLRQEMNEGKVFQGMREALITFP 850
Query: 801 PTYKYDH---GTDRYDTSEKARIPSWTDRILYKGENLQPMAYSDAKLNL----------- 846
PTYK++ G YD+ EK RIP+W DR++Y+ Q ++Y++ L
Sbjct: 851 PTYKFEKNKPGLGGYDSGEKKRIPAWCDRVIYRDN--QSISYTECSLKCPVVSSTIMYEA 908
Query: 847 ------SDHKPXXXXXXXXXXFIDEESKIQMTKKL---------YMDYKQSHPQDSGSIN 891
SDHKP D+ + Q K+ + +S P+ S S N
Sbjct: 909 CMDVTESDHKPVRCKLHANIAHTDKSVRRQELGKIVKSNEKLRAMFEELKSVPETSVSTN 968
Query: 892 SALL 895
+ LL
Sbjct: 969 NILL 972
>At4g18010 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 595
Score = 130 bits (327), Expect = 1e-29
Identities = 76/239 (31%), Positives = 128/239 (52%), Gaps = 18/239 (7%)
Query: 628 KDLVHSC--LNKHENYIMLRAEQMSSLIILFFVKADKVGNVKRVEGSSKKTGLGGMTGNK 685
+DLV C + + Y+ + ++QM + + +++ +V ++ S GL G GNK
Sbjct: 323 EDLVEECRKVKDSQKYVRIVSKQMVGIYVSVWIRRRLRRHVNNLKVSPVGVGLMGYMGNK 382
Query: 686 GAVAIRFDYGSTSFCFINAHLSAGVNNVEERRSD---YESITKG-----ISFSRSKRIDH 737
G+V+I + CF+ +HL++G + E+R + YE I + + + + I
Sbjct: 383 GSVSISMTLYQSRMCFVCSHLTSGHKDGAEQRRNADVYEIIRRTRFASVLDTDQPRTIPC 442
Query: 738 HNSTFWLGDLNYRIELPNEKVRSILSLPDNADLDKLLEHDQLTSEMASESVFKGFMEPSI 797
H+ FW GDLNYR+ + + +VR ++S D+L DQL E+ VF G+ E I
Sbjct: 443 HDQVFWFGDLNYRLNMSDGEVRKLVS---QKRWDELKNSDQLIRELRRGHVFDGWREGPI 499
Query: 798 QFRPTYKYDHGTDRY-----DTSEKARIPSWTDRILYKGENLQPMAYSDAKLNLSDHKP 851
+F PTYKY+ +DRY EK R P+W DRIL+ G+ ++ Y +++ +SDH+P
Sbjct: 500 KFPPTYKYEFDSDRYAGENLREPEKKRAPAWCDRILWLGKGIRQECYKRSEIRMSDHRP 558
>7302845 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 357
Score = 128 bits (322), Expect = 4e-29
Identities = 107/352 (30%), Positives = 167/352 (47%), Gaps = 43/352 (12%)
Query: 562 TTTSNIKILCGTFNVNGLT-KSVDLSEWLYPIGK-----RYLPDIVVLGLQEVIEL-NAS 614
T +++ I T+NV T ++ DLS L G LPDI V+G QEV
Sbjct: 5 TAIADLCIFLLTWNVGTHTPRNQDLSSLLSLNGTTTCPDNQLPDIYVIGFQEVSTTPQVL 64
Query: 615 SILNVDTSKSQFWKDLVHSCLNKHENYIMLRAEQMSSLIILFFVKADKVGNVKRVEGSSK 674
I N D W + L+ H+ ++ + ++Q+ ++I F + + ++K +E +
Sbjct: 65 KIFNDDP-----WVLKIADSLSDHQ-FVKVDSKQLQGILITMFAQHKHIPHMKEIETEAT 118
Query: 675 KTGLGGMTGNKGAVAIRFDYGSTSFCFINAHLSAGVNNVEERRSDYESITKGISFSRS-- 732
+TGLGG+ GNKGAV+IR T F+ +HL+A ++ER DY I ++
Sbjct: 119 RTGLGGLWGNKGAVSIRLSLYGTGVAFVCSHLAAHDEKLKERIEDYHQIVDNHKYNAQGY 178
Query: 733 KRIDHHNSTFWLGDLNYRI--ELPNEKVRSILSLPDNADLDKLLEHDQLTSEMASESVFK 790
+RI H+ FW GDLN+R+ ++ VR+ + ADL KL DQL + F
Sbjct: 179 RRIFDHDFVFWFGDLNFRLSGDMSAWDVRTDVENQRYADLLKL---DQLNLLREKGNAFS 235
Query: 791 GFMEPSIQFRPTYKYDHGTDRYDTSEKARIPSWTDRILYKGE-NLQP--------MAY-S 840
E F PT+K+ GT+ Y+ R P+W DRIL++ + N+ P ++Y S
Sbjct: 236 LLEEQQPNFAPTFKFVEGTNDYNLK---RRPAWCDRILHRVQSNIYPGITLSANQLSYQS 292
Query: 841 DAKLNLSDHKPXXXXXXXXXXFIDEESKIQMTKKLYMDYKQSHPQDSGSINS 892
LSDHKP K++ + Y D ++ H GS +S
Sbjct: 293 HMDYTLSDHKPVSATF---------NYKVEAANQTYTD-EELHEMTHGSASS 334
>7295697 [I] KOG1888 Putative phosphoinositide phosphatase
Length = 858
Score = 128 bits (321), Expect = 6e-29
Identities = 118/439 (26%), Positives = 197/439 (43%), Gaps = 46/439 (10%)
Query: 131 SNQQQQHPCHD-LKKLLSN----GSFYYSSDFDLTSLLQSRGLNQH----SLSFDNYQEE 181
++Q+ HP D K++ N +FY+S +DLT LQ + D +
Sbjct: 131 TSQRPPHPHEDRYKRMFQNIDLRSNFYFSYSYDLTRTLQYNESAPRYVGAKVDLDRDEPL 190
Query: 182 YMWNSFLMQ-----EIITFRNHLDDKAKQIMDD-----------EGFLTTVIRGF-AETF 224
WN+ E + + D + + + + + +L V GF +++
Sbjct: 191 PDWNTLTSNVDKAHERVDYAFRSDSRKRFVWNAYLLQPMEGIMLKDWLLEVTHGFVSQSC 250
Query: 225 PSYIGRMPVNLTMISKQSWKRAGTRFNVRGIDDEANVANFCETEFIMYSEEYCFAVTEIR 284
S GR VN+ +++++S + AGTRF RG + + +VAN ETE I+ + A T++R
Sbjct: 251 ISIFGRH-VNVCLVARRSSRFAGTRFLKRGANFQGDVANEVETEQIVSDGQRICAFTQMR 309
Query: 285 GSVPVFWEQDTALINPKVTITRSV-EATQSTFDEHFKRLIQKYG-PVHVVNLLSTK---- 338
GS+P W QD + + PK I + + T HF+RL+ YG P+ ++NL+ +
Sbjct: 310 GSIPSHWSQDISKMVPKPQIQLDICDPYAQTPSLHFERLLFHYGAPLIMLNLVKKRERRK 369
Query: 339 -----SSEIELTRRYREHFERSKSLKLNSEIFLTEFDFHKETKEEGFAAASKIMPTLERS 393
S E+E + RY F L + FD ++++ G ++ E
Sbjct: 370 HESIISKELEYSIRYLNQF-----LPPPHRMKHIHFDMARQSRLSGGNVMEQLAIHAESI 424
Query: 394 ILENGYFSYDVKEKKQLSEQNGVFRTNCLDCLDRTNLIQQFISRYTFILFLEDFQLIKPK 453
+ G F + L Q G+ RTNC+DCLDRTN Q I + LE +K
Sbjct: 425 VQMTGMFFKAAGSEPGL--QTGIVRTNCVDCLDRTNSAQFAIGKCALGHQLERLGFVK-S 481
Query: 454 LPLIEEYDWYQKHNNIWADHGDAVSQIYTGTNALKSSFSRKGKMSFAGALSDATKSVSRM 513
L + D N++ +HGD ++ Y G+ + + + + SD +++SR
Sbjct: 482 AKLEFDSDCVTMLENLYEEHGDTLALQYGGSQLVHRIKTYRKTAPWGSQGSDVMQTLSRY 541
Query: 514 YINNFMDKNKQMNIDALLG 532
Y N F D KQ +I+ LG
Sbjct: 542 YSNTFSDTEKQHSINLFLG 560
>YNL325c [I] KOG1888 Putative phosphoinositide phosphatase
Length = 879
Score = 125 bits (315), Expect = 3e-28
Identities = 119/510 (23%), Positives = 223/510 (43%), Gaps = 66/510 (12%)
Query: 57 KLEIHGFIGLIELEGSIFIGTITGKSEVASPIPGETVNKIYGVDFFCLDSNRWDFVEFDS 116
K+ +G +G I+ ++ +T S+VA I G + I G+D + +N
Sbjct: 100 KITGYGLLGFIKFTCWYYLIMVTKYSQVAV-IGGHGIYHIDGIDIIPITNNYKK------ 152
Query: 117 NGFPIIPEEEYASSSNQQQQHPCHDLKKLLSNGSFYYSSDFDLTSLLQSRGLNQHSLSFD 176
PE+ + + + K L +FY+S +D+T+ LQ+ L + + D
Sbjct: 153 ------PEK------SSDEARLLNIFKDLDLTKTFYFSYTYDITNTLQTNILREKLKAVD 200
Query: 177 -----------NYQEEYMWNSFLMQEIITFRNHLDDKAKQIMDDEGFLTTVIRGFAETFP 225
+Y E ++WN+ L+ I + + D + +I GF +
Sbjct: 201 RCDITIPCGITDYNEMFVWNNNLLSPIFACIDTVFD----------WFQCIIHGFIDQVN 250
Query: 226 SYIGRMPVNLTMISKQSWKRAGTRFNVRGIDDEANVANFCETEFIM-------------- 271
+ + +T+I+++S AG RF RG++++ +VAN ETE I+
Sbjct: 251 VSVLGKSIYITLIARRSHHFAGARFLKRGVNNKGHVANEVETEQIVTDMILTPFHQPGNG 310
Query: 272 -YSEEYCFAVTEIRGSVPVFWEQDTALINPKVTI-TRSVEATQSTFDEHFKRLIQKY--G 327
+ + + + RGS+P++W QD + + K I V+ S HF L Q+Y G
Sbjct: 311 FFDSDRYTSFVQHRGSIPLYWTQDASNLTTKPPIRINVVDPFFSPAALHFDNLFQRYGGG 370
Query: 328 PVHVVNLLSTKSSEIELTRRYREHFER-----SKSLKLNSEIFLTEFDFHKETKEEGFAA 382
+ ++NL+ TK T+ E FE+ ++ L ++ T +D + +K++G
Sbjct: 371 TIQILNLIKTKEKTPRETKLLWE-FEQCIDYLNEFLPTLKKLDYTSWDMSRASKQDGQGV 429
Query: 383 ASKIMPTLERSILENGYFSYDVKEKKQLSEQNGVFRTNCLDCLDRTNLIQQFISRYTFIL 442
+ ++ G F ++ + Q G+ R+NC+DCLDRTN Q I +
Sbjct: 430 IEFLEKYAVNTVTTTGIF-HNGPDFASTKIQEGICRSNCIDCLDRTNAAQFVIGKRALGC 488
Query: 443 FLEDFQLIKPKLPLIEEYDWYQKHNNIWADHGDAVSQIYTGTNALKSSFSRKGKMSFAGA 502
L+ +I L + D ++ D GD ++ Y G++ + + + + ++
Sbjct: 489 QLKSLGIIDNSY-LEYDSDIVNILTELFHDLGDTIALQYGGSHLVNTMETYRKINQWSSH 547
Query: 503 LSDATKSVSRMYINNFMDKNKQMNIDALLG 532
D +S+ R Y N+F+D +Q I+ LG
Sbjct: 548 SRDMIESIKRFYSNSFVDAQRQDAINLFLG 577
>Hs5031799 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 1188
Score = 125 bits (315), Expect = 3e-28
Identities = 88/328 (26%), Positives = 149/328 (44%), Gaps = 41/328 (12%)
Query: 552 EELRKQEAQFTTTSNIKILCGTFNVNGLTKSVDLSEWLYPIGKR--------YLP-DIVV 602
++++ + ++ I I GT+N+ ++ W G+ Y+P DI V
Sbjct: 388 QQMKNKHSEQPEPDMITIFIGTWNMGNAPPPKKITSWFLSKGQGKTRDDSADYIPHDIYV 447
Query: 603 LGLQEVIELNASSILNVDTSKSQFWKDLVHSCLNKHEN--YIMLRAEQMSSLIILFFVKA 660
+G QE D + W +++ L + + + + + ++ I+ K
Sbjct: 448 IGTQE------------DPLSEKEWLEILKHSLQEITSVTFKTVAIHTLWNIRIVVLAKP 495
Query: 661 DKVGNVKRVEGSSKKTGLGGMTGNKGAVAIRFDYGSTSFCFINAHLSAGVNNVEERRSDY 720
+ + + + KTG+ GNKGAV + F + TS F+N+HL++G R +Y
Sbjct: 496 EHENRISHICTDNVKTGIANTLGNKGAVGVSFMFNGTSLGFVNSHLTSGSEKKLRRNQNY 555
Query: 721 ESITKGISFSRSKRIDHHNST------FWLGDLNYRIELPNEKVRSILSLPDNADLDKLL 774
+I + ++ K++ N T FW GDLNYR++LP + +I+ LL
Sbjct: 556 MNILRFLALG-DKKLSPFNITHRFTHLFWFGDLNYRVDLPTWEAETIIQKIKQQQYADLL 614
Query: 775 EHDQLTSEMASESVFKGFMEPSIQFRPTYKYDHGT-DRY------DTSEKARIPSWTDRI 827
HDQL +E + VF F E I F PTY+++ T D+Y T K +PSW DR+
Sbjct: 615 SHDQLLTERREQKVFLHFEEEEITFAPTYRFERLTRDKYAYTKQKATGMKYNLPSWCDRV 674
Query: 828 LYKGENLQPMAY----SDAKLNLSDHKP 851
L+K L + S + + SDH P
Sbjct: 675 LWKSYPLVHVVCQSYGSTSDIMTSDHSP 702
>At1g34120 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 605
Score = 125 bits (314), Expect = 4e-28
Identities = 69/224 (30%), Positives = 121/224 (53%), Gaps = 15/224 (6%)
Query: 640 NYIMLRAEQMSSLIILFFVKADKVGNVKRVEGSSKKTGLGGMTGNKGAVAIRFDYGSTSF 699
+Y+ + ++QM + + +V+ + ++ + S+ G+ G GNKG+V++ T F
Sbjct: 352 SYVRIVSKQMVGVFLTIWVRRNLRKHISNLCVSTVGVGIMGYIGNKGSVSVSMSIYQTPF 411
Query: 700 CFINAHLSAGVNNV--EERRSDYESITKGISF-------SRSKRIDHHNSTFWLGDLNYR 750
CF+ HLS+G + E+R D I + F + R ++ WLGDLNYR
Sbjct: 412 CFLCTHLSSGEKDTDQEKRNDDVREIHRRTQFLPHSLNANELPRSICNHEIIWLGDLNYR 471
Query: 751 IELPNEKVRSILSLPDNADLDKLLEHDQLTSEMASESVFKGFMEPSIQFRPTYKYDHGTD 810
I L EK +++ + +L+E+DQL+ EM ++F+G+ E ++ F PTYKY+ ++
Sbjct: 472 INLSYEKTHELIA---RKEWQRLVEYDQLSREMTKGNLFEGWSEGTLDFAPTYKYEIDSE 528
Query: 811 RY---DTSEKARIPSWTDRILYKGENLQPMAYSDAKLNLSDHKP 851
Y D R P+W DRI++ G+ ++ Y ++ LSDH+P
Sbjct: 529 NYIGDDPESGKRRPAWCDRIIWNGKGMKLFNYRRNEIKLSDHRP 572
>Hs20537935 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 799
Score = 124 bits (311), Expect = 8e-28
Identities = 88/313 (28%), Positives = 142/313 (45%), Gaps = 41/313 (13%)
Query: 567 IKILCGTFNVNGLTKSVDLSEWLYPIGKR--------YLP-DIVVLGLQEVIELNASSIL 617
I I GT+N+ ++ W G+ Y+P DI V+G QE
Sbjct: 14 ITIFIGTWNMGNAPPPKKITSWFLSKGQGKTRDDSADYIPHDIYVIGTQE---------- 63
Query: 618 NVDTSKSQFWKDLVHSCLNKHEN--YIMLRAEQMSSLIILFFVKADKVGNVKRVEGSSKK 675
D + W +++ L + + + + + ++ I+ K + + + + K
Sbjct: 64 --DPLSEKEWLEILKHSLQEITSVTFKTVAIHTLWNIRIVVLAKPEHENRISHICTDNVK 121
Query: 676 TGLGGMTGNKGAVAIRFDYGSTSFCFINAHLSAGVNNVEERRSDYESITKGISFSRSKRI 735
TG+ GNKGAV + F + TS F+N+HL++G R +Y +I + ++ K++
Sbjct: 122 TGIANTLGNKGAVGVSFMFNGTSLGFVNSHLTSGSEKKLRRNQNYMNILRFLALG-DKKL 180
Query: 736 DHHNST------FWLGDLNYRIELPNEKVRSILSLPDNADLDKLLEHDQLTSEMASESVF 789
N T FW GDLNYR++LP + +I+ LL HDQL +E + VF
Sbjct: 181 SPFNITHRFTHLFWFGDLNYRVDLPTWEAETIIQKIKQQQYADLLSHDQLLTERREQKVF 240
Query: 790 KGFMEPSIQFRPTYKYDHGT-DRY------DTSEKARIPSWTDRILYKGENLQPMAY--- 839
F E I F PTY+++ T D+Y T K +PSW DR+L+K L +
Sbjct: 241 LHFEEEEITFAPTYRFERLTRDKYAYTKQKATGMKYNLPSWCDRVLWKSYPLVHVVCQSY 300
Query: 840 -SDAKLNLSDHKP 851
S + + SDH P
Sbjct: 301 GSTSDIMTSDHSP 313
>CE00123 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 398
Score = 124 bits (311), Expect = 8e-28
Identities = 77/257 (29%), Positives = 130/257 (49%), Gaps = 23/257 (8%)
Query: 600 IVVLGLQEVI--ELNASSILNVDTSKSQFWKDLVHSCLNKHENYIMLRAEQMSSLIILFF 657
+V +GLQEV E ++L W + S +N + ++L ++ +L F
Sbjct: 36 LVAIGLQEVAHSETIGGAVLT--------WATTIASWMNTNGRMVLLAKTFQATNQVLIF 87
Query: 658 VKADKVGNVKRVEGSSKKTGLGGMTGNKGAVAIRFDYGST-SFCFINAHLSAGVNNVEER 716
+ +G +KR++ ++ +GG+TG+KG++ +R S S F+++H G N +R
Sbjct: 88 GRKQLIGQIKRIDYRFQRNTMGGLTGHKGSIGVRLQLASPYSIVFVDSHFIHGPENYGKR 147
Query: 717 RSDYESITKGISFSRSKRIDHHNSTFWLGDLNYRIELPNEKVRSIL-SLPDNADLDKLLE 775
Y + + SF K + + FW GD N+R+E E V +++ + + L+ L
Sbjct: 148 VEQYHT-NRNCSFPEDKSV---RAAFWFGDFNFRVE---EDVNTVIRKIKNGTHLELLDT 200
Query: 776 HDQLTSEMASESVFKGFMEPSIQFRPTYKYDHGTDRYDTSEKARIPSWTDRILYKGENLQ 835
+QL + F GF E + F PTY+ GT D R+PSWTDRILYKG+ +
Sbjct: 201 REQLKRALVERDAFIGFHEQPVTFEPTYRVTVGTTEQDGK---RVPSWTDRILYKGDGIT 257
Query: 836 PMAYSDAKLNL-SDHKP 851
++Y++ K + SDH P
Sbjct: 258 GLSYTNNKKAVASDHLP 274
>Hs4755142_1 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 1139
Score = 124 bits (310), Expect = 1e-27
Identities = 84/281 (29%), Positives = 131/281 (45%), Gaps = 26/281 (9%)
Query: 567 IKILCGTFNVNGLTKSVDLSEWLYPIGKRYLPDIVVLGLQEVIELNASSILNVDTSKSQF 626
I + GT+N+ + +++ W G D V + + I + + +V +
Sbjct: 424 ISVFIGTWNMGSVPPPKNVTSWFTSKGLGKTLDEVTVTIPHDIYVFGTQENSVGDRE--- 480
Query: 627 WKDLVHSCLNKHEN--YIMLRAEQMSSLIILFFVKADKVGNVKRVEGSSKKTGLGGMTGN 684
W DL+ L + + Y + + + ++ + VK + + V SS KTG+ GN
Sbjct: 481 WLDLLRGGLKELTDLDYRPIAMQSLWNIKVAVLVKPEHENRISHVSTSSVKTGIANTLGN 540
Query: 685 KGAVAIRFDYGSTSFCFINAHLSAGVNNVEERRSDYESITKGIS--------FSRSKRID 736
KGAV + F + TSF F+N HL++G R +Y I + +S F S R
Sbjct: 541 KGAVGVSFMFNGTSFGFVNCHLTSGNEKTARRNQNYLDILRLLSLGDRQLNAFDISLRFT 600
Query: 737 HHNSTFWLGDLNYRIELPNEKVRSILSLPDNADLDKLLEHDQLTSEMASESVFKGFMEPS 796
H FW GDLNYR+++ ++ IL+ + + LL DQL E VF F E
Sbjct: 601 H---LFWFGDLNYRLDM---DIQEILNYISRKEFEPLLRVDQLNLEREKHKVFLRFSEEE 654
Query: 797 IQFRPTYKYDHGT-DRY------DTSEKARIPSWTDRILYK 830
I F PTY+Y+ G+ D Y T + +PSW DRIL+K
Sbjct: 655 ISFPPTYRYERGSRDTYAWHKQKPTGVRTNVPSWCDRILWK 695
>Hs7662034 [I] KOG1888 Putative phosphoinositide phosphatase
Length = 907
Score = 123 bits (308), Expect = 2e-27
Identities = 119/456 (26%), Positives = 195/456 (42%), Gaps = 90/456 (19%)
Query: 148 NGSFYYSSDFDLT--------------SLLQSRGLNQHSLSFDNYQEE------------ 181
+ +FY+S +DL+ +L+S SFD +++E
Sbjct: 160 SSNFYFSYSYDLSHSLQYNLTVLRMPLEMLKSEMTQNRQESFDIFEDEGLITQGGSGVFG 219
Query: 182 --------YMWNSFLMQEIITFRNHLDDKAKQIMDDEGFLTTVIRGFAETFPSYIGRMPV 233
Y+WN L+ +II H D +L +I GF I PV
Sbjct: 220 ICSEPYMKYVWNGELL-DIIKSTVHRD-----------WLLYIIHGFCGQSKLLIYGRPV 267
Query: 234 NLTMISKQSWKRAGTRFNVRGIDDEANVANFCETEFIM-------YSEEYCFAVTEIRGS 286
+T+I+++S K AGTRF RG + E +VAN ETE I+ ++ + ++RGS
Sbjct: 268 YVTLIARRSSKFAGTRFLKRGANCEGDVANEVETEQILCDASVMSFTAGSYSSYVQVRGS 327
Query: 287 VPVFWEQDTALINPKVTIT-RSVEATQSTFDEHFKRLIQKYG-PVHVVNLLSTK------ 338
VP++W QD + + PK IT + HF ++ Q++G P+ ++NL+ +
Sbjct: 328 VPLYWSQDISTMMPKPPITLDQADPFAHVAALHFDQMFQRFGSPIIILNLVKEREKRKHE 387
Query: 339 ---SSEIELTRRYREHFERSKSLKLNSEIFLTEFDFHKETKEEGFAAASKIMPTLERSIL 395
S E+ Y F L I +D K TK + ++ E +
Sbjct: 388 RILSEELVAAVTYLNQF-----LPPEHTIVYIPWDMAKYTKSKLCNVLDRLNVIAESVVK 442
Query: 396 ENGYF-----SY--DVKEKKQLSE-----------QNGVFRTNCLDCLDRTNLIQQFISR 437
+ G+F SY ++ ++ +E Q G+ RTNC+DCLDRTN Q + +
Sbjct: 443 KTGFFVNRPDSYCSILRPDEKWNELGGCVIPTGRLQTGILRTNCVDCLDRTNTAQFMVGK 502
Query: 438 YTFILFLEDFQLI-KPKLPLIEEYDWYQKHNNIWADHGDAVSQIYTGTNALKSSFSRKGK 496
L LI KP L + D + ++ DHGD +S Y G+ + + +
Sbjct: 503 CALAYQLYSLGLIDKPNLQF--DTDAVRLFEELYEDHGDTLSLQYGGSQLVHRVKTYRKI 560
Query: 497 MSFAGALSDATKSVSRMYINNFMDKNKQMNIDALLG 532
+ D +++SR Y N F D ++Q +I+ LG
Sbjct: 561 APWTQHSKDIMQTLSRYYSNAFSDADRQDSINLFLG 596
>ECU03g1160 [I] KOG1889 Putative phosphoinositide phosphatase
Length = 518
Score = 120 bits (301), Expect = 1e-26
Identities = 102/352 (28%), Positives = 160/352 (44%), Gaps = 40/352 (11%)
Query: 180 EEYMWNSFLMQEIITFRNHLDDKAKQIMDDEGFLTTVIRGFAETFPSYIGRMPVNLTMIS 239
+++++NS +++ F H DK F I+GF + IG V L +IS
Sbjct: 129 KDFLFNSLPLEK---FLGHAGDKGSL------FSVWCIQGFFGSVD--IGT--VCLRLIS 175
Query: 240 KQSWKRAGTRFNVRGIDDEANVANFCETEFIMYSEEYCFAVTEIRGSVPVFWEQDTAL-I 298
++SW+RAG R+ RG D V+N+ ETE I+Y E + ++RGS+P+ WE
Sbjct: 176 RRSWRRAGARYFSRGSDASGYVSNYVETEQIIYDGEKTVSHLQVRGSIPLIWEHVLGREY 235
Query: 299 NPKVTITRSVEATQSTFDEHFKRLIQKYGPVHVVNLLSTKSSEIELTRRYREHFERSKSL 358
NPK+ + + + K L KYG V +NL+ E L H K L
Sbjct: 236 NPKIVV-----SDRKILHIADKVLRDKYGDVFYLNLIRNSGYEGML------HCAYEKEL 284
Query: 359 KLNSEIFLTEFDFHKETKEEGFAAASKIMPTLERSILENGYFSYDVKEKKQLSEQNGVFR 418
N++ + F+F KE K + +E+++L GY S Q+GV R
Sbjct: 285 LGNNKEGV-HFNFFKEGGILEGDTRKKFLGLVEQALLSFGYHGPG-------SLQSGVIR 336
Query: 419 TNCLDCLDRTNLIQQFISRYTFILFLEDFQLIKPKLPLIEEYDWYQKHNNIWADHGDAVS 478
TNC+DCLDRTN+ Q + L F + K + ++ +W D+G+++S
Sbjct: 337 TNCIDCLDRTNISQFIMGEIILEKQLSHFDIEDKK-------HFCEQAKCLWYDNGNSLS 389
Query: 479 QIYTGTNALKSSFSRKGKMSFAGALSDATKSVSRMYINNFMDKNKQMNIDAL 530
Y+G+ ALKS F + + L D R +IN + Q + L
Sbjct: 390 MQYSGSFALKSHFLSRKRQGVVDRLRDGIIGFQRYFINRLCHGSLQTTYEIL 441
>At1g17340 [I] KOG1888 Putative phosphoinositide phosphatase
Length = 802
Score = 115 bits (287), Expect = 5e-25
Identities = 121/449 (26%), Positives = 193/449 (42%), Gaps = 88/449 (19%)
Query: 143 KKLLS----NGSFYYSSDFDLTSLLQSR-GLNQHSLSFDNYQEEYMWNSFLMQEIITFRN 197
KKLLS + +FY+S + L LQ G + DN ++WNSFL +EI
Sbjct: 165 KKLLSVVDLSKNFYFSYTYHLMYSLQKNIGNTERGNPHDNTM--FVWNSFLTREI----- 217
Query: 198 HLDDKAKQIMDDEGFLTTVIRGFAETFPSYIGRMPVNLTMISKQSWKRAGTRFNVRGIDD 257
++I+ + + +I GF + + T+I+++S AGTR RG++D
Sbjct: 218 ------RKILQNSIWTVALIYGFFQQTKCSVSGEKFVFTIIARRSRHYAGTR---RGVND 268
Query: 258 EANVANFCETEFIMYS------EEYCFAVTEIRGSVPVFWEQDTALINPK-VTITRSVEA 310
VAN ETE I+ + +V ++RGS+P+FW Q+ ++ NP+ I +A
Sbjct: 269 IGRVANDVETEQIVSKVVPAGQKIPITSVVQVRGSIPLFWSQEASVFNPQPEIILNKKDA 328
Query: 311 TQSTFDEHFKRLIQKYG-PVHVVNLLSTKSSEIELTRRYREHFER----------SKSLK 359
HF+ L Q+YG + ++NLL T + E +++RE R +K +
Sbjct: 329 NYEATQHHFQNLRQRYGNRIIILNLLKTVTGE----KKHRETILRGEFAKTIRFINKGMD 384
Query: 360 LNSEIFLTEFDFHKETKEEGFAAASKIMPTLE---------------RSILENGYFSYDV 404
+ FD K K+ + + +LE ++ + +F+ +
Sbjct: 385 REHRLKAIHFDLSKHYKK--YCIYAPYWKSLELTDLFYCKAPSGVGAEEVIYDSFFNNPI 442
Query: 405 ---------KEKKQLSE-----QNGVFRTNCLDCLDRTNLIQQFISRYTFILFLEDFQLI 450
EK+ + QNGV RTNC+DCLDRTN Q + L +
Sbjct: 443 PSQDEEASSPEKEDMKADIFLLQNGVLRTNCIDCLDRTNFAQYAHGLVSLGHQLRTLGIS 502
Query: 451 KPKL-----PL-IEEYDWYQKHNNIWADHGDAVSQIYTGTNALKSSF-SRKGKMSFAGAL 503
P + PL IE D YQK G+ ++ Y G+ A F +G +
Sbjct: 503 GPPVVDLNNPLAIELMDAYQK-------MGNTLAMQYGGSEAHSKMFCDLRGNWNMVMRQ 555
Query: 504 SDATKSVSRMYINNFMDKNKQMNIDALLG 532
D +V R Y N + D +KQ I+ LG
Sbjct: 556 RDIFTAVRRYYSNAYQDSDKQNAINVFLG 584
>Hs18765709 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 448
Score = 114 bits (285), Expect = 8e-25
Identities = 86/280 (30%), Positives = 133/280 (46%), Gaps = 10/280 (3%)
Query: 573 TFNVNGLTKSVDLSEWLYPIGKRYLPDIVVLGLQEVIELNASSI-LNVDTSKSQFWKDLV 631
T+NV +DLS+ L + DI V+GLQE LN+ I L D + + W +
Sbjct: 20 TWNVASAAPPLDLSDLLQLNNRNLNLDIYVIGLQE---LNSGIISLLSDAAFNDSWSSFL 76
Query: 632 HSCLNKHENYIMLRAEQMSSLIILFFVKADKVGNVKRVEGSSKKTGLGGMTGNKGAVAIR 691
L+ ++I + +M +++L F K + ++ + S TGL G GNKG V I
Sbjct: 77 MDVLSPL-SFIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNIC 135
Query: 692 FDYGSTSFCFINAHLSAGVNNVEERRSDYESITK--GISFSRSKRIDHHNSTFWLGDLNY 749
IN HL ++N +R ++ I + I H+ W GD+N+
Sbjct: 136 LKLYGYYVSIINCHLPPHISNNYQRLEHFDRILEMQNCEGRDIPNILDHDLIIWFGDMNF 195
Query: 750 RIELPNEKVRSILSLPDNADLDKLLEHDQLTSEMASESVFKGFMEPSIQFRPTYKYDHGT 809
RIE + + + N L E DQL+ + + + F E + F PTYK+D +
Sbjct: 196 RIE--DFGLHFVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNS 253
Query: 810 DRYDTSEKARIPSWTDRILYKGENLQPMAYSDAKLNLSDH 849
+ YDTSEK R P+WTDRIL++ + QP A D + + H
Sbjct: 254 NDYDTSEKKRKPAWTDRILWRLKR-QPCAGPDTPIPPASH 292
>SPAC3C7.01c [I] KOG1889 Putative phosphoinositide phosphatase
Length = 323
Score = 110 bits (275), Expect = 1e-23
Identities = 75/220 (34%), Positives = 108/220 (49%), Gaps = 13/220 (5%)
Query: 315 FDEHFKRLIQKYGP-VHVVNLLSTKSSEIELTRRYREHFERSKSLKLNSEIFLTEFDFHK 373
F +HF+ L YG + VVNLL K E L + + +R+K N + +D+HK
Sbjct: 2 FGKHFQELANDYGDNLVVVNLLDQKGREAPLRSGFEKLCKRNK----NPPLSYVYYDYHK 57
Query: 374 ETKEEGFAAASKIMPTLERSILENGYFSYDVKEKKQLSEQNGVFRTNCLDCLDRTNLIQQ 433
+ G + ++ ++E Y Y K + Q RTNC+DCLDRTN+IQ
Sbjct: 58 Q----GSRNLPLFLAEIQSLLIEGKY--YAEHGSKTTAMQTNFVRTNCMDCLDRTNVIQT 111
Query: 434 FISRYTFILFLEDFQLIKPKLPLIEEYD-WYQKHNNIWADHGDAVSQIYTGTNALKSSFS 492
I+++ + L D ++ L EEYD + Q IWA+ GD +S +YTGT ALK +
Sbjct: 112 SIAQFILNMQLHDIGVLSSSESL-EEYDSFLQDFRLIWANTGDYISDLYTGTPALKGDVT 170
Query: 493 RKGKMSFAGALSDATKSVSRMYINNFMDKNKQMNIDALLG 532
R G + GA D R +NNF D Q + D LG
Sbjct: 171 RHGTRTIFGAFKDLLNCFRRYILNNFFDGMLQDSYDLGLG 210
>At3g43220 [I] KOG1888 Putative phosphoinositide phosphatase
Length = 794
Score = 108 bits (271), Expect = 4e-23
Identities = 115/433 (26%), Positives = 186/433 (42%), Gaps = 102/433 (23%)
Query: 178 YQEEYMWNSFLMQEIITFRNHLDDKAKQIMDDEGFLTTVIRGFAETFPSYIGRMPVNLTM 237
Y++ ++WN FL + I R+HL + + GF F + S G+ +T+
Sbjct: 171 YEKMFVWNEFLTRGI---RHHLRNTLWTVALVYGF-------FKQASLSESGK-DFKITL 219
Query: 238 ISKQSWKRAGTRFNVRGIDDEANVANFCETEFIM---YSEEYCFAVTEI---RGSVPVFW 291
I+++S AGTR+ RG++ +VAN ETE I+ E++ ++ + RGS+P+FW
Sbjct: 220 IARRSRHNAGTRYLKRGVNRNGDVANDVETEQIVSEDVPEDHPMQISSVVQNRGSIPLFW 279
Query: 292 EQDTALINPKVTITRS-VEATQSTFDEHFKRLIQKYG-PVHVVNLLSTKSSEIELTRRYR 349
Q+T+ +N K I S E HF L+++YG P+ ++NL+ TK RR R
Sbjct: 280 SQETSRLNLKPDIVLSKKEPNYEATRLHFDNLVERYGNPIIILNLIKTKE------RRPR 333
Query: 350 EHFER----------SKSLKLNSEIFLTEFDFHKE------------------------- 374
E R +K L + + +D HK
Sbjct: 334 ESILREEFVNAIDFINKDLPEENRLRFLHWDLHKHFRSKTKNVLALLCKVATCALMLTDL 393
Query: 375 ---------TKEEGFAAASK-------IMP------------TLERSILENGYFSYDVKE 406
T E+ + +S I P +LE+ + +Y +
Sbjct: 394 FYYQVTPAMTIEDSMSLSSSSDADTGDISPHTSSDDDNGDHDSLEKKSSRSKNIAYGKCD 453
Query: 407 KKQLSEQNGVFRTNCLDCLDRTNLIQ-----QFISRYTFILFLEDFQLIKPKLPL-IEEY 460
K Q+GV RTNC+DCLDRTN+ Q + + +L + D I+ PL I
Sbjct: 454 VKPPRLQSGVLRTNCIDCLDRTNVAQYAYGWAALGQQLHVLGIRDVPAIELDDPLAISLM 513
Query: 461 DWYQKHNNIWADHGDAVSQIYTGTNALKSSFS-RKGKMSFAGALSDATKSVSRMYINNFM 519
Y++ GD ++ Y G+ A FS R+G+ A + +++ R Y N +M
Sbjct: 514 GLYER-------MGDTLAHQYGGSAAHNKVFSERRGQWRAATQSQEFLRTLQRYYNNAYM 566
Query: 520 DKNKQMNIDALLG 532
D +KQ I+ LG
Sbjct: 567 DADKQDAINIFLG 579
>Hs22068673 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 454
Score = 105 bits (261), Expect = 5e-22
Identities = 63/191 (32%), Positives = 97/191 (49%), Gaps = 21/191 (10%)
Query: 700 CFINAHLSAGVNNVEERRSDYESITKGISFSR--SKRIDHHNSTFWLGDLNYRIELPNEK 757
CF+N HL A ++ E+R+ ++++I F ++ I H+ FW GDLN+RIE +
Sbjct: 3 CFLNCHLPAHMDKAEQRKDNFQTILSLQQFQGPGAQGILDHDLVFWFGDLNFRIE--SYD 60
Query: 758 VRSILSLPDNADLDKLLEHDQLTSEMASESVFKGFMEPSIQFRPTYKYDHGTDRYDTSEK 817
+ + D+ L +L E DQL + + KGF E + F PT+K+D GT++YDTS K
Sbjct: 61 LHFVKFAIDSDQLHQLWEKDQLNMAKNTWPILKGFQEGPLNFAPTFKFDVGTNKYDTSAK 120
Query: 818 ARIPSWTDRILY--------------KGENLQPMAY---SDAKLNLSDHKPXXXXXXXXX 860
R P+WTDRIL+ K LQ + S + +SDHKP
Sbjct: 121 KRKPAWTDRILWKVKAPGGGPSPSGRKSHRLQVTQHSYRSHMEYTVSDHKPVAAQFLLQF 180
Query: 861 XFIDEESKIQM 871
F D+ +++
Sbjct: 181 AFRDDMPLVRL 191
>Hs18765707 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 372
Score = 99.0 bits (245), Expect = 4e-20
Identities = 65/212 (30%), Positives = 102/212 (47%), Gaps = 5/212 (2%)
Query: 640 NYIMLRAEQMSSLIILFFVKADKVGNVKRVEGSSKKTGLGGMTGNKGAVAIRFDYGSTSF 699
++I + +M +++L F K + ++ + S TGL G GNKG V I
Sbjct: 8 SFIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICLKLYGYYV 67
Query: 700 CFINAHLSAGVNNVEERRSDYESITK--GISFSRSKRIDHHNSTFWLGDLNYRIELPNEK 757
IN HL ++N +R ++ I + I H+ W GD+N+RIE +
Sbjct: 68 SIINCHLPPHISNNYQRLEHFDRILEMQNCEGRDIPNILDHDLIIWFGDMNFRIE--DFG 125
Query: 758 VRSILSLPDNADLDKLLEHDQLTSEMASESVFKGFMEPSIQFRPTYKYDHGTDRYDTSEK 817
+ + N L E DQL+ + + + F E + F PTYK+D ++ YDTSEK
Sbjct: 126 LHFVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSNDYDTSEK 185
Query: 818 ARIPSWTDRILYKGENLQPMAYSDAKLNLSDH 849
R P+WTDRIL++ + QP A D + + H
Sbjct: 186 KRKPAWTDRILWRLKR-QPCAGPDTPIPPASH 216
>At5g20840 [I] KOG1888 Putative phosphoinositide phosphatase
Length = 774
Score = 96.3 bits (238), Expect = 2e-19
Identities = 94/315 (29%), Positives = 140/315 (43%), Gaps = 80/315 (25%)
Query: 178 YQEEYMWNSFLMQEIITFRNHLDDKAKQIMDDEGFLTTVIRGFAETFPSYIGRMPVNLTM 237
Y++ ++WN FL + R+HL + + GF F +T S GR LT+
Sbjct: 172 YKKMFVWNEFLTRGT---RHHLRNTLWTVALVYGF-------FKQTILSEAGRN-FKLTL 220
Query: 238 ISKQSWKRAGTRFNVRGIDDEANVANFCETEFIMYSE------EYCFAVTEIRGSVPVFW 291
I+++S AGTR+ RGI++ NVAN ETE I+ + +V + RGS+P+FW
Sbjct: 221 IARRSRHNAGTRYLKRGINESGNVANDVETEQIVSEDVPVDRPMQISSVVQNRGSIPLFW 280
Query: 292 EQDTALINPKVTITRSVEATQSTFDEHFKRLIQKYG-PVHVVNLLST---KSSEIELTRR 347
Q+T+ + K I V HF+ L+++YG P+ ++NL+ T K E L
Sbjct: 281 SQETSRMKVKPDIATRV---------HFENLVERYGVPIIILNLIKTNERKPRESILRAE 331
Query: 348 YREHFE-RSKSLKLNSEIFLTEFDFHK--ETKEE------GFAAASKIMPT------LER 392
+ + +K L + + +D HK +K E G AA +M T L
Sbjct: 332 FANAIDFINKDLPEENRLRFLHWDLHKHFHSKTENVLALLGKVAACALMLTGFFYYQLTP 391
Query: 393 SILENGYFS--------------------YDVKEK---------------KQLSEQNGVF 417
++ GY S YD EK K Q+GV
Sbjct: 392 AMKLEGYMSLSSSDADTSPHNSSDDDSRDYDSLEKNCRPSKNVANGDYDVKPSRLQSGVL 451
Query: 418 RTNCLDCLDRTNLIQ 432
RTNC+DCLDRTN+ Q
Sbjct: 452 RTNCIDCLDRTNVAQ 466
>YOL065c [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 384
Score = 87.8 bits (216), Expect = 8e-17
Identities = 86/288 (29%), Positives = 121/288 (41%), Gaps = 39/288 (13%)
Query: 592 IGKRYLPDIVVLGLQEVIELNASSILNVDTSKSQFWKDLVHSCLNKH-------ENYIML 644
I + L D+ VLG QEV+ + S V+ +CLN+ E Y L
Sbjct: 39 ISQLELQDLYVLGFQEVVPIWQGSFPAVNRDLIDRITTTAVNCLNEKVSATQGDEQYSCL 98
Query: 645 RAEQMSSLIILFFVKADKVGNVKRVEGSSKKTGLGGMTGN--KGAVAIRFDYGSTS---- 698
+ ++ I+ + + K + K+ G G G KG I F
Sbjct: 99 GVNSLGAITIIVLYNNNAL---KVKDDILKRNGKCGWFGTHLKGGTLISFQMTRNGEENW 155
Query: 699 --FCFINAHLSA--GVNNVEERRSDYESITKGISFSRSKRIDHHNSTFWLGDLNYRIELP 754
F +I AHL+A GVNN +R DY+ I + S + DH F+LGDLN+R+
Sbjct: 156 ERFSYICAHLNANEGVNNRNQRIDDYKRIMSEVCDSEVAKSDHF---FFLGDLNFRVTST 212
Query: 755 NEKVRSILSLPDNADLDKLLEHDQ---LTSEMASESVFKGFMEPSIQFRPTYKYDHGTDR 811
+ + S L +LLE+ + L + E + KGF E I F PTYK+
Sbjct: 213 YDPTTNYSS---TTTLRRLLENHEELNLLRKGEDEPLCKGFQELKITFPPTYKFK--LFE 267
Query: 812 YDTSEKARIPSWTDRILYKGENLQPMAYSDA--------KLNLSDHKP 851
+T RIPSW DRILYK + A L SDH+P
Sbjct: 268 KETYNTKRIPSWCDRILYKSYAVPTFAQEGTYHSVPRSNALLFSDHQP 315
>At1g22620 [I] KOG1888 Putative phosphoinositide phosphatase
Length = 925
Score = 86.7 bits (213), Expect = 2e-16
Identities = 77/298 (25%), Positives = 138/298 (45%), Gaps = 41/298 (13%)
Query: 143 KKLLSN----GSFYYSSDFDLTSLLQSRGLN--QHSLSFDNYQEEYMWNSFLMQEIITFR 196
KKLLS+ F+YS + + LQ L+ + + +DN ++WNS+L Q I +
Sbjct: 170 KKLLSSVDLTKDFFYSYTYPIMQSLQKNVLSSGEEGMPYDNI---FVWNSYLTQPIRSRC 226
Query: 197 NHLDDKAKQIMDDEGFLTTVIRGFAETFPSYIGRMPVNLTMISKQSWKRAGTRFNVRGID 256
N+ + ++ G + I ++T++S++S AGTR+ RG++
Sbjct: 227 NNTI-----------WTLALVHGHFKQIRLSIYGRDFSVTLVSRRSRHFAGTRYLKRGVN 275
Query: 257 DEANVANFCETEFIMYSEE------YCFAVTEIRGSVPVFWEQDTALINPKVTI-TRSVE 309
D VAN ETE ++ +E +V ++RGS+P+FW Q+ + +PK I + +
Sbjct: 276 DRGRVANDVETEQLVLDDEAGSCKGKMSSVVQMRGSIPLFWSQEASRFSPKPDIFLQRYD 335
Query: 310 ATQSTFDEHFKRLIQKYG-PVHVVNLLST-----------KSSEIELTRRYREHFERSKS 357
T + HF+ L+ +YG P+ V+NL+ T + E+ L R + S
Sbjct: 336 PTYESTKMHFEDLVNRYGNPIIVLNLIKTNIHGNIQTVEKRPREMVLRREFANAVGYLNS 395
Query: 358 L-KLNSEIFLTEFDFHKETKEEGFAAASKIMPTLERSI-LENGYFSYDVKEKKQLSEQ 413
+ + + + +DFHK K + + + ++ L YFS K K+ + Q
Sbjct: 396 IFREENHLKFIHWDFHKFAKSKSANVLAVLGAVASEALDLTGLYFSGKPKIVKKKASQ 453
Score = 63.9 bits (154), Expect = 1e-09
Identities = 49/145 (33%), Positives = 68/145 (46%), Gaps = 15/145 (10%)
Query: 413 QNGVFRTNCLDCLDRTNLIQ-----QFISRYTFILFLEDFQLIKPKLPLIEE-YDWYQKH 466
Q+GV RTNC+DCLDRTN+ Q + R + L D I P + D YQ
Sbjct: 519 QSGVLRTNCIDCLDRTNVAQYAYGLAALGRQLHAMGLSDTPKIDPDSSIAAALMDMYQ-- 576
Query: 467 NNIWADHGDAVSQIYTGTNALKSSF-SRKGKMSFAGALSDATKSVSRMYINNFMDKNKQM 525
GDA++Q Y G+ A + F R+GK + KS+ R Y N + D KQ
Sbjct: 577 -----SMGDALAQQYGGSAAHNTVFPERQGKWKATTQSREFLKSIKRYYSNTYTDGEKQD 631
Query: 526 NIDALLGRL-PHQHSVELFDPINDY 549
I+ LG P + L++ +DY
Sbjct: 632 AINLFLGYFQPQEGKPALWELDSDY 656
>At1g65580 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 993
Score = 85.1 bits (209), Expect = 5e-16
Identities = 93/346 (26%), Positives = 143/346 (40%), Gaps = 88/346 (25%)
Query: 545 PINDYVNEELRKQEAQFTTTSNIKILCGTFNVNGLTKSVD-LSEWLYPIGKRYLPDIVVL 603
P+++ + EL +E ++ N+KIL GT+NV S D L WL +IVV+
Sbjct: 511 PLDNVLRAELAGKEFLYSRIENLKILAGTWNVGEGRASTDSLVSWLGCAATGV--EIVVV 568
Query: 604 GLQEVIELNASSILNVDTSKSQFWKDLVHSCLNKHENYIMLRAEQMSSLIILFFVKADKV 663
GLQEV E+ A +L + +K + L + + D +
Sbjct: 569 GLQEV-EMGAG-VLAMSAAKET----------------VGLEGSPLGQWWL------DMI 604
Query: 664 GNVKRVEGSSKKTGLGGMTGNKGAVAIRFDYGSTSFCFINAHLSAGVNNVEERRSDYESI 723
G G+S G+T +G A+ GVN +E R
Sbjct: 605 GKTLDEAGASF-----GVTMPRGGNAL------------------GVNTIEAR------- 634
Query: 724 TKGISFSRSKRIDHHNSTFWLGDLNYRIE-LPNEKVRSILSLPDNADLDKLLEHDQLTSE 782
+ + +LGD NYR++ + ++ R +S D L E DQL +E
Sbjct: 635 ---------PELSEADMVIFLGDFNYRLDDITYDETRDFIS---QRCFDWLREKDQLHTE 682
Query: 783 MASESVFKGFMEPSIQFRPTYKYDH---GTDRYDTSEKARIPSWTDRILYKGEN------ 833
M + +VF+G E I+F PTYK++ G YD+ EK RIP+W DRILY+
Sbjct: 683 MEAGNVFQGMREAIIRFPPTYKFERHQAGLAGYDSGEKKRIPAWCDRILYRDNKKHLGAE 742
Query: 834 -------LQPMAYSDAKLNL--SDHKPXXXXXXXXXXFIDEESKIQ 870
+ ++ DA + + SDHKP +DE + Q
Sbjct: 743 CSLDCPVVSSISQYDACMEVTDSDHKPVRCVFSVKIARVDESVRRQ 788
>CE28690 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 363
Score = 70.9 bits (172), Expect = 1e-11
Identities = 81/323 (25%), Positives = 133/323 (41%), Gaps = 47/323 (14%)
Query: 567 IKILCGTFNVN--GLTKSVDLSEWLYPIGKRYLPDIVVLGLQEVIELN--ASSILNVDTS 622
+K+ T+N+N G+ L++ + G+ DI + LQE+ +N +
Sbjct: 6 LKVCTVTWNINEKGVKILSHLAQKIAERGQEMDSDIFFISLQEIPSTAPLVPKTINFRLT 65
Query: 623 KSQFWK------DLVHSCLNKHENYIMLRAEQMSSLIILFFVKAD-------------KV 663
K F ++ LN H Y+ RA S ++I+F + +
Sbjct: 66 KISFRTFHEEALRILEPVLNGHRLYLSHRA--WSQMVIVFIRQKHLRYAIREFRSYNLES 123
Query: 664 GNVKRVEGSSKKTGLGGMTG---NKGAVAIRFDYGSTSFCFINAHLSAGVNNVEERRSDY 720
++K +E G M KGA+A+ I HLS ++R DY
Sbjct: 124 NSLKFLEPQVSFIASGAMAKPVRTKGAIAVCLRLYQRFIVLIGCHLSHATP--QQRIQDY 181
Query: 721 ESITKGISFSRSKRIDHH--------NSTFWLGDLNYRIELP-NEKVRSILSLPDNADLD 771
+ + + F + R H + W+GDLN+R+ + N R + + D
Sbjct: 182 AKVVRTLRFPQLARFHAHAKDEIFGSDVVLWIGDLNFRVTVESNVDWRDPEKITEKTFRD 241
Query: 772 KLLEHDQLTSEMASESVFKGFMEPSIQFRPTYKYDHGTDRYDTSEKARIPSWTDRILY-- 829
+ E ++L S + F F E I+F PT+K++ TD Y RIPS+TDR+L+
Sbjct: 242 -VFETEELASHRKKQLAFTDFKEAPIKFPPTHKFEPDTDNY---VPKRIPSFTDRVLFWV 297
Query: 830 -KGENLQPMAYSDAK-LNLSDHK 850
E LQ + Y + SDHK
Sbjct: 298 RNSEWLQNIQYDCMRGTTPSDHK 320
>ECU10g1370 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 322
Score = 66.6 bits (161), Expect = 2e-10
Identities = 66/230 (28%), Positives = 99/230 (42%), Gaps = 33/230 (14%)
Query: 626 FWKDLVHSCLNKHENYIMLRAEQMSSLIILFFVKADKVGNVKRVEGSSKKTGLGGMTG-N 684
F+ +V S L + +Y M+ A+++ L + K +R + K GLG + N
Sbjct: 42 FYSGVVRSVLKMYPSYKMVSADRVLGLWSIVLSK-------ERHSTTVMKIGLGFLGFIN 94
Query: 685 KGAVAIRFDYGSTSFCFINAHLSAGVNNVEERRSDYESITKGISFSRS-KRIDHHNSTFW 743
KGA R G FI+ HLSA N ++R+ + + + I S K ID +
Sbjct: 95 KGACVTRISNG---VMFISCHLSAHQENSKKRQEEIRKVFECICDEESLKGID---TVVL 148
Query: 744 LGDLNYRIELPNEKVRSILSLPDNADLDKLLEHDQLTSEMASESVFKGFMEPSIQFRPTY 803
GD+N+R+ +P D + DQ + F+E I+F PTY
Sbjct: 149 AGDMNFRVS----------GVPRALDYSRARPGDQCNE---FRRAYPTFLEEVIRFGPTY 195
Query: 804 KYDHGTDRYDTSEKARIPSWTDRILYKGE-NLQPMAYSDA-KLNLSDHKP 851
KY GTD + R PSW DR+ + YS + +SDHKP
Sbjct: 196 KYITGTDELC---RKRHPSWCDRVFVSSSCTCRFNTYSSIHSVKISDHKP 242
>At3g59770 [I] KOG1888 Putative phosphoinositide phosphatase
Length = 1616
Score = 63.9 bits (154), Expect = 1e-09
Identities = 78/352 (22%), Positives = 140/352 (39%), Gaps = 69/352 (19%)
Query: 141 DLKKLLSNGSFYYSSDFDLTSLLQSRGLNQHSLSFDNYQEEYMWNSFLMQEIITFRNHLD 200
+L +L +G Y+ D+T SR + + +E++WN +L + F+N
Sbjct: 146 ELTELDIDGKHYFCDTRDITRPFPSR------MPLQSPDDEFVWNRWLS---VPFKN--- 193
Query: 201 DKAKQIMDDEGFLTTVIRGFAETFP-SYIGRMPVNLTMISKQSWKRAGTRFNVRGIDDEA 259
+ +++GFAE P G++ + +++++S GTR+ RGI+ +
Sbjct: 194 ------IGLPEHCVILLQGFAEYRPFGSSGQLEGIVALMARRSRLHPGTRYLARGINSCS 247
Query: 260 NVANFCETEFIMY-----SEEYCF-AVTEIRGSVPVFWEQDTALINPKVTITRSVEATQS 313
N E E +++ + F + RG++P++W + + + I +
Sbjct: 248 GTGNEVECEQLVWIPKRNGQSIAFNSYIWRRGTIPIWWGAELKMTAAEAEIYVADRDPYK 307
Query: 314 TFDEHFKRLIQKYG------------------PVHVVNLLSTKS--SEIELTRRYRE--H 351
E+++RL ++Y P+ VNLL + SE L + + E +
Sbjct: 308 GSTEYYQRLSKRYDTRNLDAPVGENQKKKAFVPIVCVNLLRSGEGKSECILVQHFEESMN 367
Query: 352 FERSKSLKLNSEIFLTEFDFHKETKEEGFAAASKIM------PTLERSILENGYFSYDVK 405
F +S + + L +D+H K +G + + PT+ I E Y +
Sbjct: 368 FIKSSGKLPYTRVHLINYDWHASVKLKGEQQTIEGLWMYLKSPTMAIGISEGDYLPSRQR 427
Query: 406 EKKQLSE----------------QNGVFRTNCLDCLDRTNLIQQFISRYTFI 441
K E QNGV R NC D LDRTN F F+
Sbjct: 428 LKDCRGEVICIDDIEGAFCLRSHQNGVIRFNCADSLDRTNAASFFGGLQVFV 479
>Hs22066536 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 162
Score = 52.8 bits (125), Expect = 3e-06
Identities = 43/145 (29%), Positives = 67/145 (45%), Gaps = 5/145 (3%)
Query: 573 TFNVNGLTKSVDLSEWLYPIGKRYLPDIVVLGLQEVIELNASSI-LNVDTSKSQFWKDLV 631
T+NV +DLS+ L + DI V+GLQE LN+ I L D + + W +
Sbjct: 20 TWNVASAAPPLDLSDLLQLNNRNLNLDIYVIGLQE---LNSGIISLLSDAAFNDSWSSFL 76
Query: 632 HSCLNKHENYIMLRAEQMSSLIILFFVKADKVGNVKRVEGSSKKTGLGGMTGNKGAVAIR 691
L+ ++I + +M +++L F K + ++ + S TGL G GNKG V I
Sbjct: 77 MDVLSPL-SFIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNIC 135
Query: 692 FDYGSTSFCFINAHLSAGVNNVEER 716
IN HL ++N +R
Sbjct: 136 LKLYGYYVSIINCHLPPHISNNYQR 160
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.317 0.134 0.388
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 58,187,118
Number of Sequences: 60738
Number of extensions: 2408883
Number of successful extensions: 7016
Number of sequences better than 1.0e-05: 69
Number of HSP's better than 0.0 without gapping: 49
Number of HSP's successfully gapped in prelim test: 20
Number of HSP's that attempted gapping in prelim test: 6691
Number of HSP's gapped (non-prelim): 95
length of query: 1093
length of database: 30,389,216
effective HSP length: 117
effective length of query: 976
effective length of database: 23,282,870
effective search space: 22724081120
effective search space used: 22724081120
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)