ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI6474 check: MH BK KOG1080 Chromatin structure and dynamics Histone H3 (Lys4) methyltransferase complex, subunit SET1 and related methyltransferases
r_klactVI6474 check: MH BK KOG1080 Transcription Histone H3 (Lys4) methyltransferase complex, subunit SET1 and related methyltransferases
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI6474 2248261 2251260 1000
(1000 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YHR119w [BK] KOG1080 Histone H3 (Lys4) methyltransferase complex... 741 0.0
SPCC306.04c [BK] KOG1080 Histone H3 (Lys4) methyltransferase com... 261 5e-69
7289568 [BK] KOG1080 Histone H3 (Lys4) methyltransferase complex... 202 2e-51
Hs22059579 [BK] KOG1080 Histone H3 (Lys4) methyltransferase comp... 201 4e-51
CE27736 [BK] KOG1080 Histone H3 (Lys4) methyltransferase complex... 194 6e-49
CE27735 [BK] KOG1080 Histone H3 (Lys4) methyltransferase complex... 194 6e-49
CE01158 [BK] KOG1080 Histone H3 (Lys4) methyltransferase complex... 194 6e-49
At5g42400 [BK] KOG1080 Histone H3 (Lys4) methyltransferase compl... 186 1e-46
Hs5174569 [K] KOG1084 Transcription factor TCF20 148 4e-35
7290222 [R] KOG4443 Putative transcription factor HALR/MLL3 invo... 147 8e-35
Hs7662046 [K] KOG1084 Transcription factor TCF20 144 9e-34
CE16398 [R] KOG4443 Putative transcription factor HALR/MLL3 invo... 141 4e-33
At1g05830_2 [BK] KOG1080 Histone H3 (Lys4) methyltransferase com... 141 4e-33
At5g53430 [BK] KOG1080 Histone H3 (Lys4) methyltransferase compl... 139 2e-32
At2g31630 [BK] KOG1080 Histone H3 (Lys4) methyltransferase compl... 135 4e-31
Hs4505197 [R] KOG4443 Putative transcription factor HALR/MLL3 in... 128 5e-29
Hs10864041 [R] KOG4443 Putative transcription factor HALR/MLL3 i... 125 3e-28
At1g76710 [U] KOG4442 Clathrin coat binding protein/Huntingtin i... 112 4e-24
At4g30860 [K] KOG1081 Transcription factor NSD1 and related SET ... 102 2e-21
At1g77300 [U] KOG4442 Clathrin coat binding protein/Huntingtin i... 100 9e-21
Hs19923586 [K] KOG1081 Transcription factor NSD1 and related SET... 100 1e-20
CE02822 [U] KOG4442 Clathrin coat binding protein/Huntingtin int... 99 4e-20
Hs7661774 [U] KOG4442 Clathrin coat binding protein/Huntingtin i... 96 2e-19
Hs21361095 [K] KOG1079 Transcriptional repressor EZH1 96 2e-19
Hs19923202 [K] KOG1079 Transcriptional repressor EZH1 95 5e-19
HsM4758324 [K] KOG1079 Transcriptional repressor EZH1 95 6e-19
Hs8922081 [K] KOG1083 Putative transcription factor ASH1/LIN-59 94 1e-18
Hs19913361 [K] KOG1081 Transcription factor NSD1 and related SET... 94 1e-18
Hs19913348 [K] KOG1081 Transcription factor NSD1 and related SET... 94 1e-18
SPAC29B12.02c [U] KOG4442 Clathrin coat binding protein/Huntingt... 93 2e-18
Hs13699811 [K] KOG1081 Transcription factor NSD1 and related SET... 91 9e-18
7301645 [K] KOG1081 Transcription factor NSD1 and related SET do... 91 1e-17
7293772 [K] KOG1083 Putative transcription factor ASH1/LIN-59 90 2e-17
At3g59960 [K] KOG1081 Transcription factor NSD1 and related SET ... 89 4e-17
At2g44150 [K] KOG1081 Transcription factor NSD1 and related SET ... 89 4e-17
7294815 [K] KOG1079 Transcriptional repressor EZH1 87 1e-16
7292880 [U] KOG4442 Clathrin coat binding protein/Huntingtin int... 85 5e-16
Hs13375930 [BK] KOG1082 Histone H3 (Lys9) methyltransferase SUV3... 85 6e-16
At2g23380 [K] KOG1079 Transcriptional repressor EZH1 85 6e-16
At4g27910 [BK] KOG1080 Histone H3 (Lys4) methyltransferase compl... 84 1e-15
At4g02020 [K] KOG1079 Transcriptional repressor EZH1 82 3e-15
Hs22045532 [BK] KOG1082 Histone H3 (Lys9) methyltransferase SUV3... 80 2e-14
Hs5730039_1 [BK] KOG1082 Histone H3 (Lys9) methyltransferase SUV... 80 2e-14
YJL168c [U] KOG4442 Clathrin coat binding protein/Huntingtin int... 79 4e-14
CE28067 [K] KOG1079 Transcriptional repressor EZH1 78 8e-14
At2g23750 [BK] KOG1082 Histone H3 (Lys9) methyltransferase SUV39... 78 8e-14
Hs4507321 [BK] KOG1082 Histone H3 (Lys9) methyltransferase SUV39... 77 1e-13
Hs18426879 [BK] KOG1082 Histone H3 (Lys9) methyltransferase SUV3... 75 4e-13
Hs18375637 [BK] KOG1082 Histone H3 (Lys9) methyltransferase SUV3... 75 4e-13
7299982 [BK] KOG1082 Histone H3 (Lys9) methyltransferase SUV39H1... 74 1e-12
At3g61740 [BK] KOG1080 Histone H3 (Lys4) methyltransferase compl... 73 2e-12
CE27623 [BK] KOG1082 Histone H3 (Lys9) methyltransferase SUV39H1... 72 6e-12
Hs21314722 [BK] KOG1082 Histone H3 (Lys9) methyltransferase SUV3... 70 2e-11
ECU09g1750 [K] KOG1079 Transcriptional repressor EZH1 70 2e-11
CE27781 [K] KOG1081 Transcription factor NSD1 and related SET do... 70 2e-11
SPBC428.08c_2 [BK] KOG1082 Histone H3 (Lys9) methyltransferase S... 69 3e-11
At2g35160_2 [BK] KOG1082 Histone H3 (Lys9) methyltransferase SUV... 68 8e-11
CE08681 [U] KOG4442 Clathrin coat binding protein/Huntingtin int... 67 1e-10
CE13601 [K] KOG1083 Putative transcription factor ASH1/LIN-59 64 1e-09
7290020 [BK] KOG1082 Histone H3 (Lys9) methyltransferase SUV39H1... 63 3e-09
At3g03750 [BK] KOG1082 Histone H3 (Lys9) methyltransferase SUV39... 62 6e-09
At2g22740_2 [BK] KOG1082 Histone H3 (Lys9) methyltransferase SUV... 61 8e-09
7299871 [R] KOG1085 Predicted methyltransferase (contains a SET ... 61 1e-08
Hs6912652 [B] KOG1141 Predicted histone methyl transferase 60 2e-08
At5g13960_2 [BK] KOG1082 Histone H3 (Lys9) methyltransferase SUV... 59 5e-08
CE25069 [B] KOG1141 Predicted histone methyl transferase 57 1e-07
At2g24740_2 [BK] KOG1082 Histone H3 (Lys9) methyltransferase SUV... 56 2e-07
Hs15042945 [R] KOG1085 Predicted methyltransferase (contains a S... 54 1e-06
At1g73100_2 [BK] KOG1082 Histone H3 (Lys9) methyltransferase SUV... 54 1e-06
At1g17770_2 [BK] KOG1082 Histone H3 (Lys9) methyltransferase SUV... 54 1e-06
Hs13994282 [B] KOG1141 Predicted histone methyl transferase 54 2e-06
CE19602 [R] KOG1085 Predicted methyltransferase (contains a SET ... 53 3e-06
7291849 [B] KOG1141 Predicted histone methyl transferase 52 6e-06
At4g15180 [BK] KOG1080 Histone H3 (Lys4) methyltransferase compl... 51 8e-06
>YHR119w [BK] KOG1080 Histone H3 (Lys4) methyltransferase complex subunit SET1
and related methyltransferases
Length = 1080
Score = 741 bits (1913), Expect = 0.0
Identities = 451/1057 (42%), Positives = 601/1057 (56%), Gaps = 76/1057 (7%)
Query: 2 SGYYN--RQYSHFHGNNDRYQTGRYAYQENGNRYKGFQRNGSGNRRY--------SREGF 51
S YN R+Y+H G RY R N + + + N S + Y SR G
Sbjct: 42 SSQYNQRRRYNHNDGTRRRYNDDRPHSSNNASTRQYYATNNSQSGPYVNKKSDISSRRGM 101
Query: 52 GSQLRNNENESRPIRSQSRGISEIPRNPFATRPVVSAKYDRDEFNTKYHYYDIVSKRLRN 111
+N N + S S + RP +Y+ D +K+HY+D + N
Sbjct: 102 SQSRYSNSNVHNTLASSSGSLPTESALLLQQRPPSVLRYNTDNLKSKFHYFDPIKGEFFN 161
Query: 112 ESSFKKWKS--EKIPEHGYVTTTELIASDKQ-KPILMARQPEQTSVDPRIRPMNGDAVSG 168
+ WK+ ++ E GY EL D Q K + R PE + DPR NG SG
Sbjct: 162 KDKMLSWKATDKEFSETGYYVVKEL--QDGQFKFKIKHRHPEIKASDPRNE--NGIMTSG 217
Query: 169 SISAKKRYRKLRSALVRNSRIPYDSFYIGPEPPKEIIVYPSASNQQPIAAALSEAIIKNY 228
++ +RK R++L+ RI YD + +GP P EI+VYP+ Q + + IKNY
Sbjct: 218 KVAT---HRKCRNSLILLPRISYDRYSLGPPPSCEIVVYPA---QDSTTTNIQDISIKNY 271
Query: 229 FKSFGEIAHFEQFMDPNSALPLYVYLIKFTGPVSQPDAPYKAAYKASEKFKDAPYTVSGI 288
FK +GEI+HFE F DPNSALPL+VYLIK+ + + KAA+ A K + + + G
Sbjct: 272 FKKYGEISHFEAFNDPNSALPLHVYLIKYASSDGKINDAAKAAFSAVRKHESSGCFIMGF 331
Query: 289 KFNVILNQNTVLNSIKDKLIKQNAARVTEVNK-AKRAIAEKSSGQKPQVIRG-------- 339
KF VILN++++LN+I K ++ N ++ ++ + K+A +++ +K + ++G
Sbjct: 332 KFEVILNKHSILNNIISKFVEINVKKLQKLQENLKKAKEKEAENEKAKELQGKDITLPKE 391
Query: 340 ---------------VPYDLTQVVNNRPVLFVPAKITFYHRFNAADFRYQLRKYNWAKII 384
+PYDL VVNNRPVL V HRF DF+Y+LR Y AK I
Sbjct: 392 PKVDTLSHSSGSEKRIPYDLLGVVNNRPVLHVSKIFVAKHRFCVEDFKYKLRGYRCAKFI 451
Query: 385 DHYTGVYIVFHDLENAKACLEYESGALVINSHRTHSPIQIEFTFIEPK----RRLQSNIT 440
DH TG+YI+F+D+ +A+ C ESG L I S PI I+F I P+ R + +
Sbjct: 452 DHPTGIYIIFNDIAHAQTCSNAESGNLTIMSRSRRIPILIKFHLILPRFQNRTRFNKSSS 511
Query: 441 NQRDINKPRKIEYSSTEELLEASTKQILKDLHNIIKRDILRRLVGPIIFDTLNPANYPEV 500
+ N P I+Y S EE +EA+ KQILKDL + DI +RL+GP +FD L+ AN+PE+
Sbjct: 512 SSNSTNVP--IKYESKEEFIEATAKQILKDLEKTLHVDIKKRLIGPTVFDALDHANFPEL 569
Query: 501 VXXXXXXXXXXXXXXXSQ-KKTTIKAKPA---EFDIFSLYGPASKTKKLKRDRKADLGKR 556
+ S+ + +K K +FD+F LYG +K+ K R L
Sbjct: 570 LAKRELKEKEKRQQIASKIAEDELKRKEEAKRDFDLFGLYGGYAKSNKRNLKRHNSLALD 629
Query: 557 HLYTEESPDHQRKKKPKVEHMSHLLNDEISTREDTV--------DSLXXXXXXXXXXXXX 608
H + ++K ++ M+HLLN+E ++E T S
Sbjct: 630 HTSLK-----RKKLSNGIKPMAHLLNEETDSKETTPLNDEGITRVSKEHDEEDENMTSSS 684
Query: 609 XXXXXDIISDESKKQSSVITTPEEDLPESAASL-PDER-SKELLQYEGKYKPIASEFPTP 666
+ D+ K S TTPE D L PD+ S ++L YKP A+E P P
Sbjct: 685 SEEEEEEAPDKKFKSESEPTTPESDHLHGIKPLVPDQNGSSDVLDASSMYKPTATEIPEP 744
Query: 667 VYPYDDFDLNKSKQLSLDKFQLALKDEEDFSILKGIVSEKSKDITTDYTPFLPYSMWKLY 726
VYP +++DL S+ LS Q A+KDEED ILK ++S + +T + + L Y +W+
Sbjct: 745 VYPPEEYDLKYSQTLSSMDLQNAIKDEEDMLILKQLLSTYTPTVTPETSAALEYKIWQSR 804
Query: 727 QQIEQNGIIRDNQIALNEKEFDSTLASTTGSFIADGFKKIPDKLKSSYLLHHRRLAQPLN 786
+++ + D QI LN FDS L + SF A+GF+KI DKLK +YL H RR+ QPLN
Sbjct: 805 RKVLEEEKASDWQIELNGTLFDSELQPGS-SFKAEGFRKIADKLKINYLPHRRRVHQPLN 863
Query: 787 TVHNHQEQNFMA---LNGTESTNQEADLEQDNHNASSRLNRVFQRRFQQDIEAQRAAIGF 843
TV+ H E+N ES+N+E +SSR NR RRFQQDIEAQ+AAIG
Sbjct: 864 TVNIHNERNEYTPELCQREESSNKEPSDSVPQEVSSSRDNRASNRRFQQDIEAQKAAIGT 923
Query: 844 ESDLLSLNQLTKRKKPVTFARSAIHNWGLYALEPIAAKEMIIEYVGESIRQPVAEMREKR 903
ES+LLSLNQL KRKKPV FARSAIHNWGLYAL+ IAAKEMIIEYVGE IRQPVAEMREKR
Sbjct: 924 ESELLSLNQLNKRKKPVMFARSAIHNWGLYALDSIAAKEMIIEYVGERIRQPVAEMREKR 983
Query: 904 YIKSGIGSSYLFRIDENTVIDATKRGGIARFINHCCEPSCTAKIIKVDGRKRIVIYALRD 963
Y+K+GIGSSYLFR+DENTVIDATK+GGIARFINHCC+P+CTAKIIKV GR+RIVIYALRD
Sbjct: 984 YLKNGIGSSYLFRVDENTVIDATKKGGIARFINHCCDPNCTAKIIKVGGRRRIVIYALRD 1043
Query: 964 IGTNEELTYDYKFERETDEGERLPCLCGAPSCKGFLN 1000
I +EELTYDYKFERE D+ ERLPCLCGAP+CKGFLN
Sbjct: 1044 IAASEELTYDYKFEREKDDEERLPCLCGAPNCKGFLN 1080
>SPCC306.04c [BK] KOG1080 Histone H3 (Lys4) methyltransferase complex subunit SET1
and related methyltransferases
Length = 920
Score = 261 bits (666), Expect = 5e-69
Identities = 243/895 (27%), Positives = 391/895 (43%), Gaps = 142/895 (15%)
Query: 191 YDSFYIGPEPPKEIIVYPSASNQQPIAAALSEAIIKNYFKSFGEIAHFEQFMDPNSALPL 250
Y+ +GPEPP ++ V SN P+ + ++ +FKSFGE+ + ++P + L
Sbjct: 83 YNENSLGPEPPTQVFV----SNISPLVTSEQ---LRYHFKSFGEVFDLDLKLNPYTGTSL 135
Query: 251 YVYLIKFTGPVSQPDAPYKAAYKASE----KFKDAPYTVSGIKFNVILNQ--NTVLNSIK 304
+ I F S A + A + +F P +V + + + LN+++
Sbjct: 136 GLCCISFDKRSSISVAAHSAKIAVQQANGLRFSGKPLSVVLDRDGSLCEEAFKKALNAVE 195
Query: 305 -----DKLIKQNAARVTEVNKAKRAIAEK----------------SSG-----------Q 332
+ L KQ R E ++ K + A S+G Q
Sbjct: 196 KQFQEETLQKQRFEREDESSRQKLSAAMNEDIPPWRQPSKNSQTLSNGDLQHSKVQNVDQ 255
Query: 333 KPQVIRGVPYDLTQVVNNRPVLFVPAKITFYHRFNAADFRYQLRKYNWAKIIDHYTGVYI 392
K + D+ + +N+ L + + R D ++ RK+ + KI + G YI
Sbjct: 256 KSGFLTSSETDVPKNINDYIYLLIDDRFVPPDRVYYTDIKHHFRKFLYEKIYMNKDGFYI 315
Query: 393 VFHDLENAKACLEYESGALVINSHRTHSPIQIEFTFIEPKRRLQSNITNQRDINKPRKIE 452
F++ A C V N I+++F I + + + R + P
Sbjct: 316 TFNNYREASNCYRALDRTYVQNCR-----IKLKFHDIPSRTKEDGKKSAVRRVVLP---- 366
Query: 453 YSSTEELLEASTKQILKDLHNIIKRDILRRLVGPIIFDTLNPANYPEV---------VXX 503
EE +T +L+DL + RD+ +++GP IF L+ P V V
Sbjct: 367 ---PEEAYAEATSVVLRDLEAALLRDVKSKIIGPAIFKYLHSMPKPSVKEELQENLLVSS 423
Query: 504 XXXXXXXXXXXXXSQKKTTIKAKPAEFDIFSL-YGPASKTK-KLKRDRKADLGKRHLY-- 559
K ++ D + SKTK KL+R R+ R L+
Sbjct: 424 TSVPDVPLKIESTVGKLPSLPKFKKRVDSSKMNLSAGSKTKSKLQRRRRRRHEARPLHYQ 483
Query: 560 ---------TEESPDHQ--------RKKKPKVEHMSHLLNDEIS-----TREDTVDSLXX 597
+E D + R ++ K+ + + +DE + T ++
Sbjct: 484 LNQMYNSSASEAESDQELLLSSGDERVERGKIGSIKSVKSDEATPVFSDTSDENDKFHRF 543
Query: 598 XXXXXXXXXXXXXXXXDIISDESKKQSSVITTPEEDLPESAASLPDE------RSKELLQ 651
D S + + I +P +P+S +++ DE E+L
Sbjct: 544 RTKSKISKKKYEKMEVDYTSSSETESDASILSPSAAIPKSGSAIKDELISPKKEIDEVLA 603
Query: 652 YEGKYKPIASEFPTPVYPYDDFDLNKSKQ---LSLDKFQLALKDEEDFSILK-GIVSEKS 707
K++ + VY Y N + L LD Q +K++ED+S L+ + E
Sbjct: 604 LAPKWRINEFDETGSVY-YGALPYNYPEDDVLLDLDGLQYLVKNDEDYSYLQEALKDEPL 662
Query: 708 KDITTDYTPFLPYSMWKLYQQI--EQNGIIRDNQIALNEKEFDSTLASTTGSFIADGFKK 765
DI + W ++ +NG ++ A+ + ++T+GS ++G+
Sbjct: 663 MDINDP-------NFWAYERKSCKFKNGDVKYGDTAILPEPKGYFRSNTSGSAKSEGYYI 715
Query: 766 IPDKLKSSYLLHHRRLAQPLNTVHNHQEQNFMALNGTESTNQEADLEQDNHNASSRLNRV 825
IP KS YL R ++T+ + ST++ +SR+NRV
Sbjct: 716 IPTTEKSLYLPLRNR--STIDTI-------------SHSTSR----------ITSRMNRV 750
Query: 826 FQRRFQQDIEAQRAAIGFESDLLSLNQLTKRKKPVTFARSAIHNWGLYALEPIAAKEMII 885
RR +E ++ + E+DLL N L RKK + F S IH GL+A+E I +M+I
Sbjct: 751 NNRRLAAGVE--KSQLPAEADLLRFNALKARKKQLHFGPSRIHTLGLFAMENIDKNDMVI 808
Query: 886 EYVGESIRQPVAEMREKRYIKSGIGSSYLFRIDENTVIDATKRGGIARFINHCCEPSCTA 945
EY+GE IRQ VA+ REK Y++ GIG SYLFRIDE+ ++DATK+G IARFINH C P+C A
Sbjct: 809 EYIGEIIRQRVADNREKNYVREGIGDSYLFRIDEDVIVDATKKGNIARFINHSCAPNCIA 868
Query: 946 KIIKVDGRKRIVIYALRDIGTNEELTYDYKFERETDEGERLPCLCGAPSCKGFLN 1000
+II+V+G+++IVIYA RDI EELTYDYKF E D ++PCLCGAP+C+G+LN
Sbjct: 869 RIIRVEGKRKIVIYADRDIMHGEELTYDYKFPEEAD---KIPCLCGAPTCRGYLN 920
>7289568 [BK] KOG1080 Histone H3 (Lys4) methyltransferase complex subunit SET1
and related methyltransferases
Length = 177
Score = 202 bits (514), Expect = 2e-51
Identities = 97/157 (61%), Positives = 121/157 (76%), Gaps = 3/157 (1%)
Query: 844 ESDLLSLNQLTKRKKPVTFARSAIHNWGLYALEPIAAKEMIIEYVGESIRQPVAEMREKR 903
ES+LL NQL RKK + FA+SAIH+WGL+A+EPIAA EM+IEYVG+ IR VA++RE +
Sbjct: 24 ESELLKFNQLKFRKKQLKFAKSAIHDWGLFAMEPIAADEMVIEYVGQMIRPVVADLRETK 83
Query: 904 YIKSGIGSSYLFRIDENTVIDATKRGGIARFINHCCEPSCTAKIIKVDGRKRIVIYALRD 963
Y GIGSSYLFRID T+IDATK G +ARFINH C P+C AK+I ++ K+IVIY+ +
Sbjct: 84 YEAIGIGSSYLFRIDMETIIDATKCGNLARFINHSCNPNCYAKVITIESEKKIVIYSKQP 143
Query: 964 IGTNEELTYDYKFERETDEGERLPCLCGAPSCKGFLN 1000
IG NEE+TYDYKF E E++PCLCGA C+G LN
Sbjct: 144 IGINEEITYDYKFPL---EDEKIPCLCGAQGCRGTLN 177
>Hs22059579 [BK] KOG1080 Histone H3 (Lys4) methyltransferase complex subunit SET1
and related methyltransferases
Length = 772
Score = 201 bits (512), Expect = 4e-51
Identities = 115/260 (44%), Positives = 153/260 (58%), Gaps = 23/260 (8%)
Query: 741 ALNEKEFDSTLASTTGSFIADGFKKIPDKLKSSYLLHHRRLAQPLNTVHNHQEQNFMALN 800
A +K D TG ++GF I K K YL R + +
Sbjct: 536 AKKKKRDDGIREHVTGCARSEGFYTIDKKDKLRYLNSSRA-----------------STD 578
Query: 801 GTESTNQEADLEQDNHNASSRLNRVFQRRFQQDIEAQRAAIGFESDLLSLNQLTKRKKPV 860
+ Q + H AS+R +RR +Q +SDLL NQL RKK +
Sbjct: 579 EPPADTQGMSIPAQPH-ASTRAGS--ERRSEQRRLLSSFTGSCDSDLLKFNQLKFRKKKL 635
Query: 861 TFARSAIHNWGLYALEPIAAKEMIIEYVGESIRQPVAEMREKRYIKSGIGSSYLFRIDEN 920
F +S IH+WGL+A+EPIAA EM+IEYVG++IRQ +A+MREKRY GIGSSY+FR+D +
Sbjct: 636 KFCKSHIHDWGLFAMEPIAADEMVIEYVGQNIRQVIADMREKRYEDEGIGSSYMFRVDHD 695
Query: 921 TVIDATKRGGIARFINHCCEPSCTAKIIKVDGRKRIVIYALRDIGTNEELTYDYKFERET 980
T+IDATK G ARFINH C P+C AK+I V+ +K+IVIY+ + I NEE+TYDYKF
Sbjct: 696 TIIDATKCGNFARFINHSCNPNCYAKVITVESQKKIVIYSKQHINVNEEITYDYKF---P 752
Query: 981 DEGERLPCLCGAPSCKGFLN 1000
E ++PCLCG+ +C+G LN
Sbjct: 753 IEDVKIPCLCGSENCRGTLN 772
>CE27736 [BK] KOG1080 Histone H3 (Lys4) methyltransferase complex subunit SET1
and related methyltransferases
Length = 1510
Score = 194 bits (493), Expect = 6e-49
Identities = 125/322 (38%), Positives = 177/322 (54%), Gaps = 39/322 (12%)
Query: 690 LKDEEDFSILKGIVSEKSKDITTDYTPFLPYSMWKLYQQI--EQNGIIRDNQIA------ 741
L D ED L+ ++E ++ + LP+ ++++ ++ ++R N I
Sbjct: 1217 LPDLEDQWYLRAALNEMQSEVKS--ADELPWKKMLTFKEMLRSEDPLLRLNPIRSKKGLP 1274
Query: 742 ---LNEKEFDSTLASTTGSFIADGFKKIPDKLKSSYLLHHRRLAQPLNTVHNHQEQNFMA 798
++E D + G A ++K+ K K S + +P N +H F
Sbjct: 1275 DAFYEDEELDGVIPVAAGCSRARPYEKMTMKQKRSLV------RRPDN--ESHPTAIFSE 1326
Query: 799 LNGTESTNQEADLEQDNHNASSRLNRVFQRRFQQDIEAQRAAIGFESDLLSLNQLTKRKK 858
+ T +Q H AS + R+ QRR + +D +NQL RKK
Sbjct: 1327 RDETAIRHQ--------HLASKDM-RLLQRRLLTSLGDAN------NDFFKINQLKFRKK 1371
Query: 859 PVTFARSAIHNWGLYALEPIAAKEMIIEYVGESIRQPVAEMREKRYIKSGIGSSYLFRID 918
+ FARS IH WGLYA+E IA EMI+EY+G++IR VAE REK Y + GIGSSYLFRID
Sbjct: 1372 MIKFARSRIHGWGLYAMESIAPDEMIVEYIGQTIRSLVAEEREKAYERRGIGSSYLFRID 1431
Query: 919 ENTVIDATKRGGIARFINHCCEPSCTAKIIKVDGRKRIVIYALRDIGTNEELTYDYKFER 978
+ VIDATKRG ARFINH C+P+C AK++ ++G KRIVIY+ I EE+TYDYKF
Sbjct: 1432 LHHVIDATKRGNFARFINHSCQPNCYAKVLTIEGEKRIVIYSRTIIKKGEEITYDYKFPI 1491
Query: 979 ETDEGERLPCLCGAPSCKGFLN 1000
E D ++ CLCGA +C+G+LN
Sbjct: 1492 EDD---KIDCLCGAKTCRGYLN 1510
>CE27735 [BK] KOG1080 Histone H3 (Lys4) methyltransferase complex subunit SET1
and related methyltransferases
Length = 1507
Score = 194 bits (493), Expect = 6e-49
Identities = 125/322 (38%), Positives = 177/322 (54%), Gaps = 39/322 (12%)
Query: 690 LKDEEDFSILKGIVSEKSKDITTDYTPFLPYSMWKLYQQI--EQNGIIRDNQIA------ 741
L D ED L+ ++E ++ + LP+ ++++ ++ ++R N I
Sbjct: 1214 LPDLEDQWYLRAALNEMQSEVKS--ADELPWKKMLTFKEMLRSEDPLLRLNPIRSKKGLP 1271
Query: 742 ---LNEKEFDSTLASTTGSFIADGFKKIPDKLKSSYLLHHRRLAQPLNTVHNHQEQNFMA 798
++E D + G A ++K+ K K S + +P N +H F
Sbjct: 1272 DAFYEDEELDGVIPVAAGCSRARPYEKMTMKQKRSLV------RRPDN--ESHPTAIFSE 1323
Query: 799 LNGTESTNQEADLEQDNHNASSRLNRVFQRRFQQDIEAQRAAIGFESDLLSLNQLTKRKK 858
+ T +Q H AS + R+ QRR + +D +NQL RKK
Sbjct: 1324 RDETAIRHQ--------HLASKDM-RLLQRRLLTSLGDAN------NDFFKINQLKFRKK 1368
Query: 859 PVTFARSAIHNWGLYALEPIAAKEMIIEYVGESIRQPVAEMREKRYIKSGIGSSYLFRID 918
+ FARS IH WGLYA+E IA EMI+EY+G++IR VAE REK Y + GIGSSYLFRID
Sbjct: 1369 MIKFARSRIHGWGLYAMESIAPDEMIVEYIGQTIRSLVAEEREKAYERRGIGSSYLFRID 1428
Query: 919 ENTVIDATKRGGIARFINHCCEPSCTAKIIKVDGRKRIVIYALRDIGTNEELTYDYKFER 978
+ VIDATKRG ARFINH C+P+C AK++ ++G KRIVIY+ I EE+TYDYKF
Sbjct: 1429 LHHVIDATKRGNFARFINHSCQPNCYAKVLTIEGEKRIVIYSRTIIKKGEEITYDYKFPI 1488
Query: 979 ETDEGERLPCLCGAPSCKGFLN 1000
E D ++ CLCGA +C+G+LN
Sbjct: 1489 EDD---KIDCLCGAKTCRGYLN 1507
>CE01158 [BK] KOG1080 Histone H3 (Lys4) methyltransferase complex subunit SET1
and related methyltransferases
Length = 739
Score = 194 bits (493), Expect = 6e-49
Identities = 125/322 (38%), Positives = 177/322 (54%), Gaps = 39/322 (12%)
Query: 690 LKDEEDFSILKGIVSEKSKDITTDYTPFLPYSMWKLYQQI--EQNGIIRDNQIA------ 741
L D ED L+ ++E ++ + LP+ ++++ ++ ++R N I
Sbjct: 446 LPDLEDQWYLRAALNEMQSEVKS--ADELPWKKMLTFKEMLRSEDPLLRLNPIRSKKGLP 503
Query: 742 ---LNEKEFDSTLASTTGSFIADGFKKIPDKLKSSYLLHHRRLAQPLNTVHNHQEQNFMA 798
++E D + G A ++K+ K K S + +P N +H F
Sbjct: 504 DAFYEDEELDGVIPVAAGCSRARPYEKMTMKQKRSLV------RRPDN--ESHPTAIFSE 555
Query: 799 LNGTESTNQEADLEQDNHNASSRLNRVFQRRFQQDIEAQRAAIGFESDLLSLNQLTKRKK 858
+ T +Q H AS + R+ QRR + +D +NQL RKK
Sbjct: 556 RDETAIRHQ--------HLASKDM-RLLQRRLLTSLGDAN------NDFFKINQLKFRKK 600
Query: 859 PVTFARSAIHNWGLYALEPIAAKEMIIEYVGESIRQPVAEMREKRYIKSGIGSSYLFRID 918
+ FARS IH WGLYA+E IA EMI+EY+G++IR VAE REK Y + GIGSSYLFRID
Sbjct: 601 MIKFARSRIHGWGLYAMESIAPDEMIVEYIGQTIRSLVAEEREKAYERRGIGSSYLFRID 660
Query: 919 ENTVIDATKRGGIARFINHCCEPSCTAKIIKVDGRKRIVIYALRDIGTNEELTYDYKFER 978
+ VIDATKRG ARFINH C+P+C AK++ ++G KRIVIY+ I EE+TYDYKF
Sbjct: 661 LHHVIDATKRGNFARFINHSCQPNCYAKVLTIEGEKRIVIYSRTIIKKGEEITYDYKFPI 720
Query: 979 ETDEGERLPCLCGAPSCKGFLN 1000
E D ++ CLCGA +C+G+LN
Sbjct: 721 EDD---KIDCLCGAKTCRGYLN 739
>At5g42400 [BK] KOG1080 Histone H3 (Lys4) methyltransferase complex subunit SET1
and related methyltransferases
Length = 1421
Score = 186 bits (473), Expect = 1e-46
Identities = 88/150 (58%), Positives = 116/150 (76%), Gaps = 3/150 (2%)
Query: 845 SDLLSLNQLTKRKKPVTFARSAIHNWGLYALEPIAAKEMIIEYVGESIRQPVAEMREKRY 904
+D+L ++QL RKK + F +S IH+WGL ALEPI A++ +IEYVGE IR ++E+RE++Y
Sbjct: 1251 ADVLKMSQLKARKKHLRFQQSKIHDWGLVALEPIEAEDFVIEYVGELIRSSISEIRERQY 1310
Query: 905 IKSGIGSSYLFRIDENTVIDATKRGGIARFINHCCEPSCTAKIIKVDGRKRIVIYALRDI 964
K GIGSSYLFR+D+ V+DATKRGGIARFINH CEP+C KII V+G+K+I IYA R I
Sbjct: 1311 EKMGIGSSYLFRLDDGYVLDATKRGGIARFINHSCEPNCYTKIISVEGKKKIFIYAKRHI 1370
Query: 965 GTNEELTYDYKFERETDEGERLPCLCGAPS 994
EE++Y+YKF E D ++PC CGAP+
Sbjct: 1371 DAGEEISYNYKFPLEDD---KIPCNCGAPN 1397
>Hs5174569 [K] KOG1084 Transcription factor TCF20
Length = 3969
Score = 148 bits (374), Expect = 4e-35
Identities = 90/224 (40%), Positives = 118/224 (52%), Gaps = 14/224 (6%)
Query: 789 HNHQEQNFMALNGTESTNQEADLEQD----------NHNASSRLNRVFQRRFQQDIEAQR 838
H +E N LN S E L + H N + + +++ R
Sbjct: 3748 HKPEEANEPPLNPHGSARAEVHLRKSAFDMFNFLASKHRQPPEYNPNDEEEEEVQLKSAR 3807
Query: 839 AAIGFESDL-LSLNQLTKR-KKPVTFARSAIHNWGLYALEPIAAKEMIIEYVGESIRQPV 896
A + + + L K K+ V RS IH GL+ I A EM+IEY G IR
Sbjct: 3808 RATSMDLPMPMRFRHLKKTSKEAVGVYRSPIHGRGLFCKRNIDAGEMVIEYAGNVIRSIQ 3867
Query: 897 AEMREKRYIKSGIGSSYLFRIDENTVIDATKRGGIARFINHCCEPSCTAKIIKVDGRKRI 956
+ REK Y GIG Y+FRID++ V+DAT G ARFINH CEP+C +++I +DG+K I
Sbjct: 3868 TDKREKYYDSKGIGC-YMFRIDDSEVVDATMHGNRARFINHSCEPNCYSRVINIDGQKHI 3926
Query: 957 VIYALRDIGTNEELTYDYKFERETDEGERLPCLCGAPSCKGFLN 1000
VI+A+R I EELTYDYKF E D +LPC CGA C+ FLN
Sbjct: 3927 VIFAMRKIYRGEELTYDYKFPIE-DASNKLPCNCGAKKCRKFLN 3969
>7290222 [R] KOG4443 Putative transcription factor HALR/MLL3 involved in
embryonic development
Length = 2304
Score = 147 bits (371), Expect = 8e-35
Identities = 73/141 (51%), Positives = 97/141 (68%), Gaps = 2/141 (1%)
Query: 860 VTFARSAIHNWGLYALEPIAAKEMIIEYVGESIRQPVAEMREKRYIKSGIGSSYLFRIDE 919
V ARS I GLYA I MIIEY+GE IR V+E+REK+Y G Y+FR+DE
Sbjct: 2166 VYLARSKIQGLGLYAARDIEKHTMIIEYIGEVIRTEVSEIREKQYESKNRGI-YMFRLDE 2224
Query: 920 NTVIDATKRGGIARFINHCCEPSCTAKIIKVDGRKRIVIYALRDIGTNEELTYDYKFERE 979
+ V+DAT GG+AR+INH C P+C +I++VD RI+I+A R I EEL+YDYKF+ E
Sbjct: 2225 DRVVDATLSGGLARYINHSCNPNCVTEIVEVDRDVRIIIFAKRKIYRGEELSYDYKFDIE 2284
Query: 980 TDEGERLPCLCGAPSCKGFLN 1000
DE ++PC CGAP+C+ ++N
Sbjct: 2285 -DESHKIPCACGAPNCRKWMN 2304
>Hs7662046 [K] KOG1084 Transcription factor TCF20
Length = 2715
Score = 144 bits (362), Expect = 9e-34
Identities = 77/144 (53%), Positives = 95/144 (65%), Gaps = 2/144 (1%)
Query: 857 KKPVTFARSAIHNWGLYALEPIAAKEMIIEYVGESIRQPVAEMREKRYIKSGIGSSYLFR 916
K+ V RSAIH GL+ I A EM+IEY G IR + + REK Y GIG Y+FR
Sbjct: 2574 KEAVGVYRSAIHGRGLFCKRNIDAGEMVIEYSGIVIRSVLTDKREKFYDGKGIGC-YMFR 2632
Query: 917 IDENTVIDATKRGGIARFINHCCEPSCTAKIIKVDGRKRIVIYALRDIGTNEELTYDYKF 976
+D+ V+DAT G ARFINH CEP+C +++I V+G+K IVI+ALR I EELTYDYKF
Sbjct: 2633 MDDFDVVDATMHGNAARFINHSCEPNCFSRVIHVEGQKHIVIFALRRILRGEELTYDYKF 2692
Query: 977 ERETDEGERLPCLCGAPSCKGFLN 1000
E D +LPC CGA C+ FLN
Sbjct: 2693 PIE-DASNKLPCNCGAKRCRRFLN 2715
>CE16398 [R] KOG4443 Putative transcription factor HALR/MLL3 involved in
embryonic development
Length = 2561
Score = 141 bits (356), Expect = 4e-33
Identities = 94/255 (36%), Positives = 131/255 (50%), Gaps = 33/255 (12%)
Query: 777 HHRRLAQPLNTVHNH-------QEQNFMALNGTESTNQEADLEQ---DNHNASSRLNRVF 826
H R QP+ H+H Q + + + S N+ Q +A+S R
Sbjct: 2309 HFRTKPQPMGGTHHHIGSASGLSSQATIIASSSSSANESLQSRQAATSVTSANSGRTRGV 2368
Query: 827 QRRFQQDIEAQRAAIGFESDLLSLN----------------QLTKR--KKPVTFARSAIH 868
+ + ++ A+ A G ++ SL+ Q +R K V ARS I
Sbjct: 2369 RSYYTEEAAARARAFGIPPEMASLSLRMETTQNAQTAFSAYQKMRREWKDRVYLARSRIA 2428
Query: 869 NWGLYALEPIAAKEMIIEYVGESIRQPVAEMREKRYIKSGIGSSYLFRIDENTVIDATKR 928
GLYA I+ + IIEY GE IR V E+RE RY+ G Y+FRIDE VIDAT
Sbjct: 2429 GLGLYAKVDISMGDFIIEYKGEIIRSEVCEVREIRYVAQNRGV-YMFRIDEEWVIDATMA 2487
Query: 929 GGIARFINHCCEPSCTAKIIKVDG---RKRIVIYALRDIGTNEELTYDYKFERETDEGER 985
GG AR+INH C+P+C+ +I+ K+I+I A R I NEELTYDY+FE E ++
Sbjct: 2488 GGPARYINHSCDPNCSTQILDAGSGAREKKIIITANRPISANEELTYDYQFELE-GTTDK 2546
Query: 986 LPCLCGAPSCKGFLN 1000
+PCLCGAP+C ++N
Sbjct: 2547 IPCLCGAPNCVKWMN 2561
>At1g05830_2 [BK] KOG1080 Histone H3 (Lys4) methyltransferase complex subunit SET1
and related methyltransferases
Length = 582
Score = 141 bits (356), Expect = 4e-33
Identities = 68/145 (46%), Positives = 96/145 (65%), Gaps = 4/145 (2%)
Query: 857 KKPVTFARSAIHNWGLYALEPIAAKEMIIEYVGESIRQPVAEMREKRYIKSGIGS-SYLF 915
+K + F +S IH +G++A P A +M+IEY GE +R P+A+ RE S +G+ +Y+F
Sbjct: 319 RKRLAFGKSGIHGFGIFAKLPHRAGDMVIEYTGELVRPPIADKREHLIYNSMVGAGTYMF 378
Query: 916 RIDENTVIDATKRGGIARFINHCCEPSCTAKIIKVDGRKRIVIYALRDIGTNEELTYDYK 975
RID VIDAT+ G IA INH CEP+C +++I V+G + I+I+A RD+ EELTYDY+
Sbjct: 379 RIDNERVIDATRTGSIAHLINHSCEPNCYSRVISVNGDEHIIIFAKRDVAKWEELTYDYR 438
Query: 976 FERETDEGERLPCLCGAPSCKGFLN 1000
F ERL C CG P C+G +N
Sbjct: 439 F---FSIDERLACYCGFPRCRGVVN 460
>At5g53430 [BK] KOG1080 Histone H3 (Lys4) methyltransferase complex subunit SET1
and related methyltransferases
Length = 1040
Score = 139 bits (350), Expect = 2e-32
Identities = 67/142 (47%), Positives = 94/142 (66%), Gaps = 2/142 (1%)
Query: 860 VTFARSAIHNWGLYALEPIAAKEMIIEYVGESIRQPVAEMREKRYIKSGIGSSYLFRIDE 919
V F RS IH WGL+A I EM++EY GE +R +A++RE RY + G YLF+I E
Sbjct: 900 VCFGRSGIHGWGLFARRNIQEGEMVLEYRGEQVRGIIADLREARYRREG-KDCYLFKISE 958
Query: 920 NTVIDATKRGGIARFINHCCEPSCTAKIIKV-DGRKRIVIYALRDIGTNEELTYDYKFER 978
V+DAT++G IAR INH C P+C A+I+ V D RIV+ A + + EELTYDY F+
Sbjct: 959 EVVVDATEKGNIARLINHSCMPNCYARIMSVGDDESRIVLIAKTTVASCEELTYDYLFDP 1018
Query: 979 ETDEGERLPCLCGAPSCKGFLN 1000
+ + ++PCLC +P+C+ F+N
Sbjct: 1019 DEPDEFKVPCLCKSPNCRKFMN 1040
>At2g31630 [BK] KOG1080 Histone H3 (Lys4) methyltransferase complex subunit SET1
and related methyltransferases
Length = 186
Score = 135 bits (339), Expect = 4e-31
Identities = 66/144 (45%), Positives = 93/144 (63%), Gaps = 3/144 (2%)
Query: 857 KKPVTFARSAIHNWGLYALEPIAAKEMIIEYVGESIRQPVAEMREKRYIKSGIGSSYLFR 916
+K + F +S IH +G++A P A +M+IEY GE +R +A+ RE+ S +Y+FR
Sbjct: 22 RKRLAFGKSGIHGFGIFAKLPHRAGDMMIEYTGELVRPSIADKREQLIYNSMGAGTYMFR 81
Query: 917 IDENTVIDATKRGGIARFINHCCEPSCTAKIIKVDGRKRIVIYALRDIGTNEELTYDYKF 976
ID+ VIDAT+ G IA INH C P+C +++I V+G + I+I+A R I EELTYDY+F
Sbjct: 82 IDDERVIDATRTGSIAHLINHSCVPNCYSRVITVNGDEHIIIFAKRHIPKWEELTYDYRF 141
Query: 977 ERETDEGERLPCLCGAPSCKGFLN 1000
GERL C CG P C+G +N
Sbjct: 142 ---FSIGERLSCSCGFPGCRGVVN 162
>Hs4505197 [R] KOG4443 Putative transcription factor HALR/MLL3 involved in
embryonic development
Length = 5262
Score = 128 bits (321), Expect = 5e-29
Identities = 68/147 (46%), Positives = 92/147 (62%), Gaps = 2/147 (1%)
Query: 854 TKRKKPVTFARSAIHNWGLYALEPIAAKEMIIEYVGESIRQPVAEMREKRYIKSGIGSSY 913
T+ K V ARS I GLYA + + M+IEY+G IR VA REK Y + G Y
Sbjct: 5118 TEWKNNVYLARSRIQGLGLYAAKDLEKHTMVIEYIGTIIRNEVANRREKIYEEQNRGI-Y 5176
Query: 914 LFRIDENTVIDATKRGGIARFINHCCEPSCTAKIIKVDGRKRIVIYALRDIGTNEELTYD 973
+FRI+ VIDAT GG AR+INH C P+C A+++ D +I+I + R I EELTYD
Sbjct: 5177 MFRINNEHVIDATLTGGPARYINHSCAPNCVAEVVTFDKEDKIIIISSRRIPKGEELTYD 5236
Query: 974 YKFERETDEGERLPCLCGAPSCKGFLN 1000
Y+F+ E D+ E +PC CGA +C+ ++N
Sbjct: 5237 YQFDFEDDQHE-IPCHCGAWNCRKWMN 5262
>Hs10864041 [R] KOG4443 Putative transcription factor HALR/MLL3 involved in
embryonic development
Length = 4025
Score = 125 bits (314), Expect = 3e-28
Identities = 66/147 (44%), Positives = 90/147 (60%), Gaps = 2/147 (1%)
Query: 854 TKRKKPVTFARSAIHNWGLYALEPIAAKEMIIEYVGESIRQPVAEMREKRYIKSGIGSSY 913
T+ K V ARS I GLYA I M+IEY+G IR VA +EK Y G Y
Sbjct: 3881 TEWKSNVYLARSRIQGLGLYAARDIEKHTMVIEYIGTIIRNEVANRKEKLYESQNRGV-Y 3939
Query: 914 LFRIDENTVIDATKRGGIARFINHCCEPSCTAKIIKVDGRKRIVIYALRDIGTNEELTYD 973
+FR+D + VIDAT GG AR+INH C P+C A+++ + +I+I + R I EEL YD
Sbjct: 3940 MFRMDNDHVIDATLTGGPARYINHSCAPNCVAEVVTFERGHKIIISSSRRIQKGEELCYD 3999
Query: 974 YKFERETDEGERLPCLCGAPSCKGFLN 1000
YKF+ E D+ ++PC CGA +C+ ++N
Sbjct: 4000 YKFDFEDDQ-HKIPCHCGAVNCRKWMN 4025
>At1g76710 [U] KOG4442 Clathrin coat binding protein/Huntingtin interacting
protein HIP1 involved in regulation of endocytosis
Length = 528
Score = 112 bits (279), Expect = 4e-24
Identities = 57/130 (43%), Positives = 76/130 (57%), Gaps = 2/130 (1%)
Query: 870 WGLYALEPIAAKEMIIEYVGESIRQPVAEMREKRYIKSGIGSSYLFRIDENTVIDATKRG 929
WGL ALE I A + I+EY GE I A+ R + Y G+ +Y+ ++ + IDATK+G
Sbjct: 101 WGLVALEEIKAGQFIMEYCGEVISWKEAKKRAQTYETHGVKDAYIISLNASEAIDATKKG 160
Query: 930 GIARFINHCCEPSCTAKIIKVDGRKRIVIYALRDIGTNEELTYDYKFERETDEGERLPCL 989
+ARFINH C P+C + V G R+ I+A I EL YDY F E G ++ CL
Sbjct: 161 SLARFINHSCRPNCETRKWNVLGEVRVGIFAKESISPRTELAYDYNF--EWYGGAKVRCL 218
Query: 990 CGAPSCKGFL 999
CGA +C GFL
Sbjct: 219 CGAVACSGFL 228
>At4g30860 [K] KOG1081 Transcription factor NSD1 and related SET domain
proteins
Length = 477
Score = 102 bits (255), Expect = 2e-21
Identities = 50/149 (33%), Positives = 82/149 (54%), Gaps = 3/149 (2%)
Query: 851 NQLTKRKKPVTFARSAIHNWGLYALEPIAAKEMIIEYVGESIRQPVAEMREKRYIKSGIG 910
N+ +++K + ++ WG+ A E I ++ I+EY+GE I E R G+
Sbjct: 299 NRPFRKEKKIKIVKTEHCGWGVEAAESINKEDFIVEYIGEVISDAQCEQRLWDMKHKGMK 358
Query: 911 SSYLFRIDENTVIDATKRGGIARFINHCCEPSCTAKIIKVDGRKRIVIYALRDIGTNEEL 970
Y+ I ++ IDAT +G +RF+NH C P+C + +V+G R+ ++A R I E L
Sbjct: 359 DFYMCEIQKDFTIDATFKGNASRFLNHSCNPNCVLEKWQVEGETRVGVFAARQIEAGEPL 418
Query: 971 TYDYKFERETDEGERLPCLCGAPSCKGFL 999
TYDY+F G + C CG+ +C+G+L
Sbjct: 419 TYDYRF---VQFGPEVKCNCGSENCQGYL 444
>At1g77300 [U] KOG4442 Clathrin coat binding protein/Huntingtin interacting
protein HIP1 involved in regulation of endocytosis
Length = 408
Score = 100 bits (250), Expect = 9e-21
Identities = 54/154 (35%), Positives = 84/154 (54%), Gaps = 3/154 (1%)
Query: 848 LSLNQLTKRKKPVTFAR--SAIHNWGLYALEPIAAKEMIIEYVGESIRQPVAEMREKRYI 905
L NQ +++K V F R S +GL LE + + +IEYVGE + E R+K Y
Sbjct: 38 LCSNQQFQKRKYVKFERFQSGKKGYGLRLLEDVREGQFLIEYVGEVLDMQSYETRQKEYA 97
Query: 906 KSGIGSSYLFRIDENTVIDATKRGGIARFINHCCEPSCTAKIIKVDGRKRIVIYALRDIG 965
G Y ++ N VIDA +G + RFINH CEP+C + V+G + I++++D+
Sbjct: 98 FKGQKHFYFMTLNGNEVIDAGAKGNLGRFINHSCEPNCRTEKWMVNGEICVGIFSMQDLK 157
Query: 966 TNEELTYDYKFERETDEGERLPCLCGAPSCKGFL 999
+ELT+DY + R + C CG+ C+G++
Sbjct: 158 KGQELTFDYNYVRVFGAAAK-KCYCGSSHCRGYI 190
>Hs19923586 [K] KOG1081 Transcription factor NSD1 and related SET domain proteins
Length = 2696
Score = 100 bits (248), Expect = 1e-20
Identities = 55/147 (37%), Positives = 82/147 (55%), Gaps = 3/147 (2%)
Query: 854 TKRKKP-VTFARSAIHNWGLYALEPIAAKEMIIEYVGESIRQPVAEMREKRYIKSGIGSS 912
+KR+ P V R+ WGL I E + EYVGE I + R + + I +
Sbjct: 1937 SKRQYPEVEIFRTLQRGWGLRTKTDIKKGEFVNEYVGELIDEEECRARIRYAQEHDITNF 1996
Query: 913 YLFRIDENTVIDATKRGGIARFINHCCEPSCTAKIIKVDGRKRIVIYALRDIGTNEELTY 972
Y+ +D++ +IDA +G ARF+NHCC+P+C + V+G R+ ++AL DI ELT+
Sbjct: 1997 YMLTLDKDRIIDAGPKGNYARFMNHCCQPNCETQKWSVNGDTRVGLFALSDIKAGTELTF 2056
Query: 973 DYKFERETDEGERLPCLCGAPSCKGFL 999
+Y E G+ + C CGAP+C GFL
Sbjct: 2057 NYNLEC-LGNGKTV-CKCGAPNCSGFL 2081
>CE02822 [U] KOG4442 Clathrin coat binding protein/Huntingtin interacting
protein HIP1 involved in regulation of endocytosis
Length = 408
Score = 98.6 bits (244), Expect = 4e-20
Identities = 53/131 (40%), Positives = 74/131 (56%), Gaps = 6/131 (4%)
Query: 871 GLYALEPIAAKEMIIEYVGESIRQPVAEMREKRYIKSGIGSSYLFRIDENTVIDATKRGG 930
GL A E IA ++I+EY GE+I + R KRY K GI SY F + N +D T++G
Sbjct: 109 GLRATEEIATGKLILEYRGEAITKAEHNKRVKRYKKDGIKHSYSFEVGRNYYVDPTRKGN 168
Query: 931 IARFINHCCEPSCTAKIIKVDGR--KRIVIYALRDIGTNEELTYDYKFERETDEGERLPC 988
ARFINH C P+ K+ V R K + I+A + I EE+T+DY D+ PC
Sbjct: 169 SARFINHSCNPNALVKVWTVPDRPMKSLGIFASKVIKPGEEITFDYGTSFRNDQ----PC 224
Query: 989 LCGAPSCKGFL 999
CG +C+G++
Sbjct: 225 QCGEAACRGWI 235
>Hs7661774 [U] KOG4442 Clathrin coat binding protein/Huntingtin interacting
protein HIP1 involved in regulation of endocytosis
Length = 591
Score = 96.3 bits (238), Expect = 2e-19
Identities = 52/177 (29%), Positives = 90/177 (50%), Gaps = 28/177 (15%)
Query: 823 NRVFQRRFQQDIEAQRAAIGFESDLLSLNQLTKRKKPVTFARSAIHNWGLYALEPIAAKE 882
NR FQR+ D+E LT++K WGL A + + +
Sbjct: 91 NRRFQRKQHADVEVI---------------LTEKK-----------GWGLRAAKDLPSNT 124
Query: 883 MIIEYVGESIRQPVAEMREKRYIKSGIGSSYLFRIDENTVIDATKRGGIARFINHCCEPS 942
++EY GE + + R K Y ++ Y + + +IDAT++G +RF+NH CEP+
Sbjct: 125 FVLEYCGEVLDHKEFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPN 184
Query: 943 CTAKIIKVDGRKRIVIYALRDIGTNEELTYDYKFERETDEGERLPCLCGAPSCKGFL 999
C + V+G+ R+ + + + + ELT+DY+F+R E ++ C CG+ +C+G+L
Sbjct: 185 CETQKWTVNGQLRVGFFTTKLVPSGSELTFDYQFQRYGKEAQK--CFCGSANCRGYL 239
>Hs21361095 [K] KOG1079 Transcriptional repressor EZH1
Length = 751
Score = 96.3 bits (238), Expect = 2e-19
Identities = 50/122 (40%), Positives = 73/122 (58%), Gaps = 2/122 (1%)
Query: 857 KKPVTFARSAIHNWGLYALEPIAAKEMIIEYVGESIRQPVAEMREKRYIKSGIGSSYLFR 916
KK + A S + WG++ +P+ E I EY GE I Q A+ R K Y K S+LF
Sbjct: 616 KKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDK--YMCSFLFN 673
Query: 917 IDENTVIDATKRGGIARFINHCCEPSCTAKIIKVDGRKRIVIYALRDIGTNEELTYDYKF 976
++ + V+DAT++G RF NH P+C AK++ V+G RI I+A R I T EEL +DY++
Sbjct: 674 LNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRY 733
Query: 977 ER 978
+
Sbjct: 734 SQ 735
>Hs19923202 [K] KOG1079 Transcriptional repressor EZH1
Length = 747
Score = 95.1 bits (235), Expect = 5e-19
Identities = 55/136 (40%), Positives = 75/136 (54%), Gaps = 13/136 (9%)
Query: 857 KKPVTFARSAIHNWGLYALEPIAAKEMIIEYVGESIRQPVAEMREKRYIKSGIGSSYLFR 916
KK + A S + WG + E + E I EY GE I Q A+ R K Y K SS+LF
Sbjct: 612 KKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELISQDEADRRGKVYDK--YMSSFLFN 669
Query: 917 IDENTVIDATKRGGIARFINHCCEPSCTAKIIKVDGRKRIVIYALRDIGTNEELTYDYKF 976
++ + V+DAT++G RF NH P+C AK++ V+G RI I+A R I EEL +DY++
Sbjct: 670 LNNDFVVDATRKGNKIRFANHSVNPNCYAKVVMVNGDHRIGIFAKRAIQAGEELFFDYRY 729
Query: 977 -----------ERETD 981
ERETD
Sbjct: 730 SQADALKYVGIERETD 745
>HsM4758324 [K] KOG1079 Transcriptional repressor EZH1
Length = 746
Score = 94.7 bits (234), Expect = 6e-19
Identities = 50/122 (40%), Positives = 72/122 (58%), Gaps = 2/122 (1%)
Query: 857 KKPVTFARSAIHNWGLYALEPIAAKEMIIEYVGESIRQPVAEMREKRYIKSGIGSSYLFR 916
KK + A S + WG++ +P+ E I EY GE I Q A+ R K Y K S+LF
Sbjct: 611 KKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDK--YMCSFLFN 668
Query: 917 IDENTVIDATKRGGIARFINHCCEPSCTAKIIKVDGRKRIVIYALRDIGTNEELTYDYKF 976
++ + V+DAT++G RF NH P+C AK++ V+G RI I+A R I T EEL DY++
Sbjct: 669 LNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFVDYRY 728
Query: 977 ER 978
+
Sbjct: 729 SQ 730
>Hs8922081 [K] KOG1083 Putative transcription factor ASH1/LIN-59
Length = 2969
Score = 93.6 bits (231), Expect = 1e-18
Identities = 52/137 (37%), Positives = 75/137 (53%), Gaps = 4/137 (2%)
Query: 864 RSAIHNWGLYALEPIAAKEMIIEYVGESIRQPVAEMREKRYIKSGIGSS-YLFRIDENTV 922
R+ WG+ EP+ A + IIEY+GE + + E R + + S Y +D V
Sbjct: 2151 RAEEKGWGIRTKEPLKAGQFIIEYLGEVVSEQ--EFRNRMIEQYHNHSDHYCLNLDSGMV 2208
Query: 923 IDATKRGGIARFINHCCEPSCTAKIIKVDGRKRIVIYALRDIGTNEELTYDYKFERETDE 982
ID+ + G ARFINH C+P+C + V+G RI +YAL+D+ ELTYDY F E
Sbjct: 2209 IDSYRMGNEARFINHSCDPNCEMQKWSVNGVYRIGLYALKDMPAGTELTYDYNFHSFNVE 2268
Query: 983 GERLPCLCGAPSCKGFL 999
++L C CG C+G +
Sbjct: 2269 KQQL-CKCGFEKCRGII 2284
>Hs19913361 [K] KOG1081 Transcription factor NSD1 and related SET domain
proteins
Length = 584
Score = 93.6 bits (231), Expect = 1e-18
Identities = 53/147 (36%), Positives = 79/147 (53%), Gaps = 3/147 (2%)
Query: 854 TKRKKPVT-FARSAIHNWGLYALEPIAAKEMIIEYVGESIRQPVAEMREKRYIKSGIGSS 912
TKR+ P T ++ WGL A I E + EYVGE I + R K ++ I
Sbjct: 277 TKRQYPETKIIKTDGKGWGLVAKRDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHF 336
Query: 913 YLFRIDENTVIDATKRGGIARFINHCCEPSCTAKIIKVDGRKRIVIYALRDIGTNEELTY 972
Y+ ID++ +IDA +G +RF+NH C+P+C V+G R+ ++A+ DI ELT+
Sbjct: 337 YMLTIDKDRIIDAGPKGNYSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTF 396
Query: 973 DYKFERETDEGERLPCLCGAPSCKGFL 999
+Y + E+ C CGA +C GFL
Sbjct: 397 NYNL--DCLGNEKTVCRCGASNCSGFL 421
>Hs19913348 [K] KOG1081 Transcription factor NSD1 and related SET domain proteins
Length = 1365
Score = 93.6 bits (231), Expect = 1e-18
Identities = 53/147 (36%), Positives = 79/147 (53%), Gaps = 3/147 (2%)
Query: 854 TKRKKPVT-FARSAIHNWGLYALEPIAAKEMIIEYVGESIRQPVAEMREKRYIKSGIGSS 912
TKR+ P T ++ WGL A I E + EYVGE I + R K ++ I
Sbjct: 1058 TKRQYPETKIIKTDGKGWGLVAKRDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHF 1117
Query: 913 YLFRIDENTVIDATKRGGIARFINHCCEPSCTAKIIKVDGRKRIVIYALRDIGTNEELTY 972
Y+ ID++ +IDA +G +RF+NH C+P+C V+G R+ ++A+ DI ELT+
Sbjct: 1118 YMLTIDKDRIIDAGPKGNYSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTF 1177
Query: 973 DYKFERETDEGERLPCLCGAPSCKGFL 999
+Y + E+ C CGA +C GFL
Sbjct: 1178 NYNL--DCLGNEKTVCRCGASNCSGFL 1202
>SPAC29B12.02c [U] KOG4442 Clathrin coat binding protein/Huntingtin interacting
protein HIP1 involved in regulation of endocytosis
Length = 798
Score = 92.8 bits (229), Expect = 2e-18
Identities = 48/130 (36%), Positives = 68/130 (51%), Gaps = 2/130 (1%)
Query: 870 WGLYALEPIAAKEMIIEYVGESIRQPVAEMREKRYIKSGIGSSYLFRIDENTVIDATKRG 929
+GL A + + EY+GE I + R ++Y GI Y + + IDATKRG
Sbjct: 192 FGLRADANLPKDTFVYEYIGEVIPEQKFRKRMRQYDSEGIKHFYFMMLQKGEYIDATKRG 251
Query: 930 GIARFINHCCEPSCTAKIIKVDGRKRIVIYALRDIGTNEELTYDYKFERETDEGERLPCL 989
+ARF NH C P+C V + R+ I+ RDI EELT+DY +R + + PC
Sbjct: 252 SLARFCNHSCRPNCYVDKWMVGDKLRMGIFCKRDIIRGEELTFDYNVDRYGAQAQ--PCY 309
Query: 990 CGAPSCKGFL 999
CG P C G++
Sbjct: 310 CGEPCCVGYI 319
>Hs13699811 [K] KOG1081 Transcription factor NSD1 and related SET domain proteins
Length = 1437
Score = 90.9 bits (224), Expect = 9e-18
Identities = 50/147 (34%), Positives = 77/147 (52%), Gaps = 3/147 (2%)
Query: 854 TKRKKP-VTFARSAIHNWGLYALEPIAAKEMIIEYVGESIRQPVAEMREKRYIKSGIGSS 912
TKR P ++ WGL I E + EYVGE I + +R KR ++ + +
Sbjct: 1140 TKRLYPDAEIIKTERRGWGLRTKRSIKKGEFVNEYVGELIDEEECRLRIKRAHENSVTNF 1199
Query: 913 YLFRIDENTVIDATKRGGIARFINHCCEPSCTAKIIKVDGRKRIVIYALRDIGTNEELTY 972
Y+ + ++ +IDA +G +RF+NH C P+C + V+G R+ ++AL DI ELT+
Sbjct: 1200 YMLTVTKDRIIDAGPKGNYSRFMNHSCNPNCETQKWTVNGDVRVGLFALCDIPAGMELTF 1259
Query: 973 DYKFERETDEGERLPCLCGAPSCKGFL 999
+Y + R C CGA +C GFL
Sbjct: 1260 NYNL--DCLGNGRTECHCGADNCSGFL 1284
>7301645 [K] KOG1081 Transcription factor NSD1 and related SET domain proteins
Length = 1401
Score = 90.5 bits (223), Expect = 1e-17
Identities = 45/128 (35%), Positives = 74/128 (57%), Gaps = 1/128 (0%)
Query: 870 WGLYALEPIAAKEMIIEYVGESIRQPVAEMREKRYIKSGIGSSYLFRIDENTVIDATKRG 929
+GL EPIA + +IEYVGE I + R ++ + + Y ++++ +IDA +G
Sbjct: 1246 FGLVNREPIAVGDFVIEYVGEVINHAEFQRRMEQKQRDRDENYYFLGVEKDFIIDAGPKG 1305
Query: 930 GIARFINHCCEPSCTAKIIKVDGRKRIVIYALRDIGTNEELTYDYKFERETDEGERLPCL 989
+ARF+NH CEP+C + V+ R+ I+A++DI N ELT++Y ++ + + C
Sbjct: 1306 NLARFMNHSCEPNCETQKWTVNCIHRVGIFAIKDIPVNSELTFNYLWD-DLMNNSKKACF 1364
Query: 990 CGAPSCKG 997
CGA C G
Sbjct: 1365 CGAKRCSG 1372
>7293772 [K] KOG1083 Putative transcription factor ASH1/LIN-59
Length = 2167
Score = 90.1 bits (222), Expect = 2e-17
Identities = 49/135 (36%), Positives = 68/135 (50%), Gaps = 2/135 (1%)
Query: 865 SAIHNWGLYALEPIAAKEMIIEYVGESIRQPVAEMREKRYIKSGIGSSYLFRIDENTVID 924
+A WG+ PIA I+EYVGE + + + R + Y +D VID
Sbjct: 1338 TADKGWGVRTKLPIAKGTYILEYVGEVVTEKEFKQRMASIYLNDT-HHYCLHLDGGLVID 1396
Query: 925 ATKRGGIARFINHCCEPSCTAKIIKVDGRKRIVIYALRDIGTNEELTYDYKFERETDEGE 984
+ G RF+NH CEP+C + V+G R+V++A R I EELTYDY F + E
Sbjct: 1397 GQRMGSDCRFVNHSCEPNCEMQKWSVNGLSRMVLFAKRAIEEGEELTYDYNFSL-FNPSE 1455
Query: 985 RLPCLCGAPSCKGFL 999
PC C P C+G +
Sbjct: 1456 GQPCRCNTPQCRGVI 1470
>At3g59960 [K] KOG1081 Transcription factor NSD1 and related SET domain
proteins
Length = 352
Score = 88.6 bits (218), Expect = 4e-17
Identities = 52/127 (40%), Positives = 70/127 (54%), Gaps = 3/127 (2%)
Query: 870 WGLYALEPIAAKEMIIEYVGESIRQPVAEMREKRYIKSGIGSSYLFRIDENTVIDATKRG 929
+G+ A E I + E IIEYVGE I + E R + + YL +I+ N VIDAT +G
Sbjct: 123 YGIVADEDINSGEFIIEYVGEVIDDKICEERLWKLNHKVETNFYLCQINWNMVIDATHKG 182
Query: 930 GIARFINHCCEPSCTAKIIKVDGRKRIVIYALRDIGTNEELTYDYKFERETDEGERLPCL 989
+R+INH C P+ + +DG RI I+A R I E+LTYDY+F G C
Sbjct: 183 NKSRYINHSCSPNTEMQKWIIDGETRIGIFATRFINKGEQLTYDYQF---VQFGADQDCY 239
Query: 990 CGAPSCK 996
CGA C+
Sbjct: 240 CGAVCCR 246
>At2g44150 [K] KOG1081 Transcription factor NSD1 and related SET domain
proteins
Length = 344
Score = 88.6 bits (218), Expect = 4e-17
Identities = 53/126 (42%), Positives = 66/126 (52%), Gaps = 3/126 (2%)
Query: 871 GLYALEPIAAKEMIIEYVGESIRQPVAEMREKRYIKSGIGSSYLFRIDENTVIDATKRGG 930
G+ A E I A E IIEYVGE I E R + G + YL I + VIDAT +G
Sbjct: 129 GIVAEEEIEAGEFIIEYVGEVIDDKTCEERLWKMKHRGETNFYLCEITRDMVIDATHKGN 188
Query: 931 IARFINHCCEPSCTAKIIKVDGRKRIVIYALRDIGTNEELTYDYKFERETDEGERLPCLC 990
+R+INH C P+ + +DG RI I+A R I E LTYDY+F G C C
Sbjct: 189 KSRYINHSCNPNTQMQKWIIDGETRIGIFATRGIKKGEHLTYDYQF---VQFGADQDCHC 245
Query: 991 GAPSCK 996
GA C+
Sbjct: 246 GAVGCR 251
>7294815 [K] KOG1079 Transcriptional repressor EZH1
Length = 760
Score = 87.4 bits (215), Expect = 1e-16
Identities = 49/119 (41%), Positives = 67/119 (56%), Gaps = 2/119 (1%)
Query: 858 KPVTFARSAIHNWGLYALEPIAAKEMIIEYVGESIRQPVAEMREKRYIKSGIGSSYLFRI 917
K + A S I WG++ E E I EY GE I Q A+ R K Y K S+LF +
Sbjct: 626 KHLLMAPSDIAGWGIFLKEGAQKNEFISEYCGEIISQDEADRRGKVYDK--YMCSFLFNL 683
Query: 918 DENTVIDATKRGGIARFINHCCEPSCTAKIIKVDGRKRIVIYALRDIGTNEELTYDYKF 976
+ + V+DAT++G RF NH P+C AK++ V G RI I+A R I EEL +DY++
Sbjct: 684 NNDFVVDATRKGNKIRFANHSINPNCYAKVMMVTGDHRIGIFAKRAIQPGEELFFDYRY 742
>7292880 [U] KOG4442 Clathrin coat binding protein/Huntingtin interacting
protein HIP1 involved in regulation of endocytosis
Length = 2362
Score = 85.1 bits (209), Expect = 5e-16
Identities = 48/141 (34%), Positives = 74/141 (52%), Gaps = 2/141 (1%)
Query: 859 PVTFARSAIHNWGLYALEPIAAKEMIIEYVGESIRQPVAEMREKRYIKSGIGSSYLFRID 918
P R+ G+ A I E I+EYVGE I E R+ Y K Y +
Sbjct: 1412 PCRVFRTEKKGCGITAELLIPPGEFIMEYVGEVIDSEEFERRQHLYSKDRNRHYYFMALR 1471
Query: 919 ENTVIDATKRGGIARFINHCCEPSCTAKIIKVDGRKRIVIYALRDIGTNEELTYDYKFER 978
VIDAT +G I+R+INH C+P+ + V+G RI ++++ I EE+T+DY++ R
Sbjct: 1472 GEAVIDATSKGNISRYINHSCDPNAETQKWTVNGELRIGFFSVKPIQPGEEITFDYQYLR 1531
Query: 979 ETDEGERLPCLCGAPSCKGFL 999
+ +R C C A +C+G++
Sbjct: 1532 YGRDAQR--CYCEAANCRGWI 1550
>Hs13375930 [BK] KOG1082 Histone H3 (Lys9) methyltransferase SUV39H1/Clr4
required for transcriptional silencing
Length = 350
Score = 84.7 bits (208), Expect = 6e-16
Identities = 51/158 (32%), Positives = 77/158 (48%), Gaps = 21/158 (13%)
Query: 862 FARSAIHNWGLYALEPIAAKEMIIEYVGESIRQPVAEMREKRYIKSGIGSSYLFRID--- 918
F S WG+ L I ++EYVGE I AE R + Y GI +YLF +D
Sbjct: 195 FRTSNGRGWGVKTLVKIKRMSFVMEYVGEVITSEEAERRGQFYDNKGI--TYLFDLDYES 252
Query: 919 ENTVIDATKRGGIARFINHCCEPSCTAKIIKVDG----RKRIVIYALRDIGTNEELTYDY 974
+ +DA + G ++ F+NH C+P+ + +D RI +++ R I EELT+DY
Sbjct: 253 DEFTVDAARYGNVSHFVNHSCDPNLQVFNVFIDNLDTRLPRIALFSTRTINAGEELTFDY 312
Query: 975 KFERETD------------EGERLPCLCGAPSCKGFLN 1000
+ + D + R C CGA +C+G+LN
Sbjct: 313 QMKGSGDISSDSIDHSPAKKRVRTVCKCGAVTCRGYLN 350
>At2g23380 [K] KOG1079 Transcriptional repressor EZH1
Length = 902
Score = 84.7 bits (208), Expect = 6e-16
Identities = 49/149 (32%), Positives = 76/149 (50%), Gaps = 7/149 (4%)
Query: 849 SLNQLTKRKKPVTFARSAIHNWGLYALEPIAAKEMIIEYVGESIRQPVAEMREKRYIKSG 908
++ L K+++ V S + WG + ++ E + EY GE I A+ R K Y +
Sbjct: 743 NMKLLLKQQQRVLLGISDVSGWGAFLKNSVSKHEYLGEYTGELISHKEADKRGKIYDREN 802
Query: 909 IGSSYLFRIDENTVIDATKRGGIARFINHCCEPSCTAKIIKVDGRKRIVIYALRDIGTNE 968
S+LF +++ V+DA ++G +F NH EP+C AK+I V G R+ I+A I E
Sbjct: 803 C--SFLFNLNDQFVLDAYRKGDKLKFANHSPEPNCYAKVIMVAGDHRVGIFAKERILAGE 860
Query: 969 ELTYDYKFERETDEGERLPCLCGAPSCKG 997
EL YDY++ E +R P P G
Sbjct: 861 ELFYDYRY-----EPDRAPAWAKKPEAPG 884
>At4g27910 [BK] KOG1080 Histone H3 (Lys4) methyltransferase complex subunit
SET1 and related methyltransferases
Length = 912
Score = 83.6 bits (205), Expect = 1e-15
Identities = 50/124 (40%), Positives = 67/124 (53%), Gaps = 5/124 (4%)
Query: 824 RVFQRRFQQDIEAQRAAIGFESDLLSLNQLTKRKKP--VTFARSAIHNWGLYALEPIAAK 881
RVF+R+ G S + + +R + V F RS IH WGL+A I
Sbjct: 784 RVFKRKINSKKGTTSPLAGKNSLMFERDWNVQRTEMDRVCFGRSGIHGWGLFARRNIQEG 843
Query: 882 EMIIEYVGESIRQPVAEMREKRYIKSGIGSSYLFRIDENTVIDATKRGGIARFINHCCEP 941
EM++EY GE +R +A++RE RY + G YLF+I E V+DAT +G IAR INH
Sbjct: 844 EMVLEYRGEQVRGSIADLREARYRRVG-KDCYLFKISEEVVVDATDKGNIARLINH--SV 900
Query: 942 SCTA 945
SC A
Sbjct: 901 SCLA 904
>At4g02020 [K] KOG1079 Transcriptional repressor EZH1
Length = 898
Score = 82.4 bits (202), Expect = 3e-15
Identities = 41/128 (32%), Positives = 74/128 (57%), Gaps = 2/128 (1%)
Query: 849 SLNQLTKRKKPVTFARSAIHNWGLYALEPIAAKEMIIEYVGESIRQPVAEMREKRYIKSG 908
++ L ++++ + +S + WG + ++ E + EY GE I A+ R K Y ++
Sbjct: 740 NMRLLLRQQQRILLGKSDVAGWGAFLKNSVSKNEYLGEYTGELISHHEADKRGKIYDRAN 799
Query: 909 IGSSYLFRIDENTVIDATKRGGIARFINHCCEPSCTAKIIKVDGRKRIVIYALRDIGTNE 968
SS+LF +++ V+DA ++G +F NH +P+C AK++ V G R+ I+A I +E
Sbjct: 800 --SSFLFDLNDQYVLDAQRKGDKLKFANHSAKPNCYAKVMFVAGDHRVGIFANERIEASE 857
Query: 969 ELTYDYKF 976
EL YDY++
Sbjct: 858 ELFYDYRY 865
>Hs22045532 [BK] KOG1082 Histone H3 (Lys9) methyltransferase SUV39H1/Clr4
required for transcriptional silencing
Length = 365
Score = 79.7 bits (195), Expect = 2e-14
Identities = 49/150 (32%), Positives = 77/150 (50%), Gaps = 22/150 (14%)
Query: 870 WGLYALEPIAAKEMIIEYVGESIRQPVAEMREKRYIKSGIGSSYLFRIDEN--------T 921
WGL LE I + EY GE + +E++ + ++++ S+Y+ I E+ T
Sbjct: 151 WGLRTLEFIPKGRFVCEYAGEVLG--FSEVQRRIHLQTKSDSNYIIAIREHVYNGQVMET 208
Query: 922 VIDATKRGGIARFINHCCEPSCTAKIIKVDGR-KRIVIYALRDIGTNEELTYDY------ 974
+D T G I RF+NH CEP+ +++D ++ ++A +DI EEL+YDY
Sbjct: 209 FVDPTYIGNIGRFLNHSCEPNLLMIPVRIDSMVPKLALFAAKDIVPEEELSYDYSGRYLN 268
Query: 975 ----KFERETDEGE-RLPCLCGAPSCKGFL 999
+ + D G+ R PC CGA SC FL
Sbjct: 269 LTVSEDKERLDHGKLRKPCYCGAKSCTAFL 298
>Hs5730039_1 [BK] KOG1082 Histone H3 (Lys9) methyltransferase SUV39H1/Clr4
required for transcriptional silencing
Length = 328
Score = 79.7 bits (195), Expect = 2e-14
Identities = 49/150 (32%), Positives = 76/150 (50%), Gaps = 22/150 (14%)
Query: 870 WGLYALEPIAAKEMIIEYVGESIRQPVAEMREKRYIKSGIGSSYLFRIDEN--------T 921
WGL LE I + EY GE + +E++ + ++++ S+Y+ I E+ T
Sbjct: 138 WGLRTLEFIPKGRFVCEYAGEVLG--FSEVQRRIHLQTKSDSNYIIAIREHVYNGQVMET 195
Query: 922 VIDATKRGGIARFINHCCEPSCTAKIIKVDGR-KRIVIYALRDIGTNEELTYDYK----- 975
+D T G I RF+NH CEP+ +++D ++ ++A +DI EEL+YDY
Sbjct: 196 FVDPTYIGNIGRFLNHSCEPNLLMIPVRIDSMVPKLALFAAKDIVPEEELSYDYSGRYLN 255
Query: 976 -----FERETDEGE-RLPCLCGAPSCKGFL 999
+ D G+ R PC CGA SC FL
Sbjct: 256 LTVSASKERLDHGKLRKPCYCGAKSCTAFL 285
>YJL168c [U] KOG4442 Clathrin coat binding protein/Huntingtin interacting
protein HIP1 involved in regulation of endocytosis
Length = 733
Score = 79.0 bits (193), Expect = 4e-14
Identities = 46/145 (31%), Positives = 70/145 (47%), Gaps = 2/145 (1%)
Query: 855 KRKKPVTFARSAIHNWGLYALEPIAAKEMIIEYVGESIRQPVAEMREKRYIKSGIGSSYL 914
K+ P+ ++ +G+ A + I A + I EY GE I + R Y + Y
Sbjct: 117 KQYAPIAIFKTKHKGYGVRAEQDIEANQFIYEYKGEVIEEMEFRDRLIDYDQRHFKHFYF 176
Query: 915 FRIDENTVIDATKRGGIARFINHCCEPSCTAKIIKVDGRKRIVIYALRDIGTNEELTYDY 974
+ IDAT +G +ARF NH C P+ V + R+ I+A R I EE+T+DY
Sbjct: 177 MMLQNGEFIDATIKGSLARFCNHSCSPNAYVNKWVVKDKLRMGIFAQRKILKGEEITFDY 236
Query: 975 KFERETDEGERLPCLCGAPSCKGFL 999
+R + ++ C C P+C GFL
Sbjct: 237 NVDRYGAQAQK--CYCEEPNCIGFL 259
>CE28067 [K] KOG1079 Transcriptional repressor EZH1
Length = 773
Score = 77.8 bits (190), Expect = 8e-14
Identities = 48/116 (41%), Positives = 62/116 (53%), Gaps = 3/116 (2%)
Query: 865 SAIHNWGLYALEPIAAKEMIIEYVGESIRQPVAEMREKRYIKSGIGSSYLFRIDENTVID 924
S I GL+ LEP E I EY GE I AE R Y + SY+F I+ ID
Sbjct: 628 SKIAGNGLFLLEPAEKDEFITEYTGERISDDEAERRGAIYDR--YQCSYIFNIETGGAID 685
Query: 925 ATKRGGIARFINHCCE-PSCTAKIIKVDGRKRIVIYALRDIGTNEELTYDYKFERE 979
+ K G +ARF NH + P+C A+ + V G RI YA R + +EELT+DY + E
Sbjct: 686 SYKIGNLARFANHDSKNPTCYARTMVVAGEHRIGFYAKRRLEISEELTFDYSYSGE 741
>At2g23750 [BK] KOG1082 Histone H3 (Lys9) methyltransferase SUV39H1/Clr4
required for transcriptional silencing
Length = 203
Score = 77.8 bits (190), Expect = 8e-14
Identities = 55/156 (35%), Positives = 71/156 (45%), Gaps = 22/156 (14%)
Query: 864 RSAIHNWGLYALEPIAAKEMIIEYVGESIRQPVAEMREKRYIKSGIGS-SYLFRIDENT- 921
R+ WGL A E I + EY+GE + Q A R +Y G G SY+ ID N
Sbjct: 51 RTESKGWGLRACEHILRGTFVCEYIGEVLDQQEANKRRNQY---GNGDCSYILDIDANIN 107
Query: 922 ------------VIDATKRGGIARFINHCCEPSCTAKIIKVDGRK----RIVIYALRDIG 965
IDAT G I+RFINH C P+ + V+ + I +YA DI
Sbjct: 108 DIGRLMEEELDYAIDATTHGNISRFINHSCSPNLVNHQVIVESMESPLAHIGLYASMDIA 167
Query: 966 TNEELTYDYKFERETDEGE-RLPCLCGAPSCKGFLN 1000
EE+T DY E E PC C A +C+G L+
Sbjct: 168 AGEEITRDYGRRPVPSEQENEHPCHCKATNCRGLLS 203
>Hs4507321 [BK] KOG1082 Histone H3 (Lys9) methyltransferase SUV39H1/Clr4
required for transcriptional silencing
Length = 412
Score = 77.0 bits (188), Expect = 1e-13
Identities = 49/158 (31%), Positives = 73/158 (46%), Gaps = 30/158 (18%)
Query: 870 WGLYALEPIAAKEMIIEYVGESIRQPVAEMREKRYIKSGIGSSYLFRID---ENTVIDAT 926
WG+ LE I ++EYVGE I AE R + Y + G++YLF +D + +DA
Sbjct: 256 WGVRTLEKIRKNSFVMEYVGEIITSEEAERRGQIYDRQ--GATYLFDLDYVEDVYTVDAA 313
Query: 927 KRGGIARFINHCCEPSCTAKIIKVDG----RKRIVIYALRDIGTNEELTYDYKFERETDE 982
G I+ F+NH C+P+ + +D RI +A R I EELT+DY + + +
Sbjct: 314 YYGNISHFVNHSCDPNLQVYNVFIDNLDERLPRIAFFATRTIRAGEELTFDYNMQVDPVD 373
Query: 983 GE---------------------RLPCLCGAPSCKGFL 999
E R+ C CG SC+ +L
Sbjct: 374 MESTRMDSNFGLAGLPGSPKKRVRIECKCGTESCRKYL 411
>Hs18426879 [BK] KOG1082 Histone H3 (Lys9) methyltransferase SUV39H1/Clr4
required for transcriptional silencing
Length = 1176
Score = 75.5 bits (184), Expect = 4e-13
Identities = 53/141 (37%), Positives = 70/141 (49%), Gaps = 16/141 (11%)
Query: 864 RSAIHNWGLYALEPIAAKEMIIEYVGESIRQPVAEMREKRYIKSGIGSSYLFRID----E 919
R+A WG+ AL+ I I EYVGE I A++RE SYLF +D E
Sbjct: 1010 RTAKMGWGVRALQTIPQGTFICEYVGELISDAEADVRE--------DDSYLFDLDNKDGE 1061
Query: 920 NTVIDATKRGGIARFINHCCEPS---CTAKIIKVDGR-KRIVIYALRDIGTNEELTYDYK 975
IDA G I+RFINH C+P+ ++ D R RI ++ RDI T EEL +DY
Sbjct: 1062 VYCIDARYYGNISRFINHLCDPNIIPVRVFMLHQDLRFPRIAFFSSRDIRTGEELGFDYG 1121
Query: 976 FERETDEGERLPCLCGAPSCK 996
+ + C CG+ CK
Sbjct: 1122 DRFWDIKSKYFTCQCGSEKCK 1142
>Hs18375637 [BK] KOG1082 Histone H3 (Lys9) methyltransferase SUV39H1/Clr4
required for transcriptional silencing
Length = 1210
Score = 75.5 bits (184), Expect = 4e-13
Identities = 53/141 (37%), Positives = 70/141 (49%), Gaps = 16/141 (11%)
Query: 864 RSAIHNWGLYALEPIAAKEMIIEYVGESIRQPVAEMREKRYIKSGIGSSYLFRID----E 919
R+A WG+ AL+ I I EYVGE I A++RE SYLF +D E
Sbjct: 1044 RTAKMGWGVRALQTIPQGTFICEYVGELISDAEADVRE--------DDSYLFDLDNKDGE 1095
Query: 920 NTVIDATKRGGIARFINHCCEPS---CTAKIIKVDGR-KRIVIYALRDIGTNEELTYDYK 975
IDA G I+RFINH C+P+ ++ D R RI ++ RDI T EEL +DY
Sbjct: 1096 VYCIDARYYGNISRFINHLCDPNIIPVRVFMLHQDLRFPRIAFFSSRDIRTGEELGFDYG 1155
Query: 976 FERETDEGERLPCLCGAPSCK 996
+ + C CG+ CK
Sbjct: 1156 DRFWDIKSKYFTCQCGSEKCK 1176
>7299982 [BK] KOG1082 Histone H3 (Lys9) methyltransferase SUV39H1/Clr4
required for transcriptional silencing
Length = 635
Score = 73.9 bits (180), Expect = 1e-12
Identities = 52/158 (32%), Positives = 72/158 (44%), Gaps = 21/158 (13%)
Query: 860 VTFARSAIHNWGLYALEPIAAKEMIIEYVGESIRQPVAEMREKRYIKSGIGSSYLFRIDE 919
V F + WG+ A + E + EY+GE I A R K Y +G +YLF +D
Sbjct: 480 VLFKTANGSGWGVRAATALRKGEFVCEYIGEIITSDEANERGKAYDDNG--RTYLFDLDY 537
Query: 920 NTV------IDATKRGGIARFINHCCEPS-----CTAKIIKVDGRKRIVIYALRDIGTNE 968
NT IDA G I+ FINH C+P+ C + + V +V + LR I E
Sbjct: 538 NTAQDSEYTIDAANYGNISHFINHSCDPNLAVFPCWIEHLNV-ALPHLVFFTLRPIKAGE 596
Query: 969 ELTYDYKFERETD-------EGERLPCLCGAPSCKGFL 999
EL++DY D R+ C CGA +C+ L
Sbjct: 597 ELSFDYIRADNEDVPYENLSTAVRVECRCGADNCRKVL 634
>At3g61740 [BK] KOG1080 Histone H3 (Lys4) methyltransferase complex subunit SET1
and related methyltransferases
Length = 902
Score = 73.2 bits (178), Expect = 2e-12
Identities = 46/130 (35%), Positives = 65/130 (49%), Gaps = 30/130 (23%)
Query: 874 ALEPIAAKEMIIEYVGESIRQPVAEMREKRYIKSGIGSSYLFRIDENTVIDATKRGGIAR 933
AL +A + IIEY G +R+ VA++RE Y G
Sbjct: 800 ALVNLAYMDGIIEYRGVKVRRSVADLREANYRSQG------------------------- 834
Query: 934 FINHC-CEPSCTAKIIKV-DGR-KRIVIYALRDIGTNEELTYDYKFERETDEGERLPCLC 990
C C P+C A+I+ + DG RIV+ A ++ EELTYDY FE + E ++PCLC
Sbjct: 835 --KDCYCMPNCYARIVSMGDGEDNRIVLIAKTNVAAGEELTYDYLFEVDESEEIKVPCLC 892
Query: 991 GAPSCKGFLN 1000
AP+C+ F+N
Sbjct: 893 KAPNCRKFMN 902
>CE27623 [BK] KOG1082 Histone H3 (Lys9) methyltransferase SUV39H1/Clr4
required for transcriptional silencing
Length = 244
Score = 71.6 bits (174), Expect = 6e-12
Identities = 49/139 (35%), Positives = 68/139 (48%), Gaps = 14/139 (10%)
Query: 870 WGLYALEPIAAKEMIIEYVGESIRQPVAEMREKRYIKSGIGSSYLFRIDE-------NTV 922
+G+ A E IAA E + EY GE I + E R + + +Y + E T
Sbjct: 103 FGVRAGEQIAAGEFVCEYAGECIGEQEVERRCREFRGD---DNYTLTLKEFFGGKPVKTF 159
Query: 923 IDATKRGGIARFINHCCEPSCTAKIIKVDGR--KRIVIYALRDIGTNEELTYDYKFERET 980
+D RG I RF+NH CEP+C + ++ GR I+A RDI EEL YDY
Sbjct: 160 VDPRLRGNIGRFLNHSCEPNCEIILARL-GRMIPAAGIFAKRDIVRGEELCYDYGHSAIE 218
Query: 981 DEGERLPCLCGAPSCKGFL 999
E +L CLC + C+ +L
Sbjct: 219 GENRKL-CLCKSEKCRKYL 236
>Hs21314722 [BK] KOG1082 Histone H3 (Lys9) methyltransferase SUV39H1/Clr4
required for transcriptional silencing
Length = 1267
Score = 70.1 bits (170), Expect = 2e-11
Identities = 45/135 (33%), Positives = 67/135 (49%), Gaps = 16/135 (11%)
Query: 870 WGLYALEPIAAKEMIIEYVGESIRQPVAEMREKRYIKSGIGSSYLFRID----ENTVIDA 925
WG+ +L+ I + EYVGE I A++RE+ SYLF +D E IDA
Sbjct: 1107 WGVRSLQDIPPGTFVCEYVGELISDSEADVREE--------DSYLFDLDNKDGEVYCIDA 1158
Query: 926 TKRGGIARFINHCCEPSCTAKIIKVDGRK----RIVIYALRDIGTNEELTYDYKFERETD 981
G ++RFINH CEP+ + + + RI ++ R I E+L +DY
Sbjct: 1159 RFYGNVSRFINHHCEPNLVPVRVFMAHQDLRFPRIAFFSTRLIEAGEQLGFDYGERFWDI 1218
Query: 982 EGERLPCLCGAPSCK 996
+G+ C CG+P C+
Sbjct: 1219 KGKLFSCRCGSPKCR 1233
>ECU09g1750 [K] KOG1079 Transcriptional repressor EZH1
Length = 537
Score = 70.1 bits (170), Expect = 2e-11
Identities = 50/127 (39%), Positives = 65/127 (50%), Gaps = 8/127 (6%)
Query: 859 PVTFARSAIHNWGLYALEPIAAKEMIIEYVGESIRQPVAEMREKRYIKSGIGSSYLFRID 918
P A S + +GL+A E ++ +IEYVGE I AE R Y G SYLF +
Sbjct: 404 PTFVAPSRVEGYGLFAKEKMSKGRFVIEYVGEIISNEEAERRGTFYDLRGC--SYLFDLY 461
Query: 919 ENT-----VIDATKRGGIARFINHCCEPS-CTAKIIKVDGRKRIVIYALRDIGTNEELTY 972
VID+ G +RFINH S A ++ V+G +RI YA RDI EEL +
Sbjct: 462 SREGKALYVIDSRFIGNRSRFINHSQRNSNLYAFVLIVNGVRRIGFYASRDICEGEELLF 521
Query: 973 DYKFERE 979
DYK+ E
Sbjct: 522 DYKYSEE 528
>CE27781 [K] KOG1081 Transcription factor NSD1 and related SET domain
proteins
Length = 898
Score = 69.7 bits (169), Expect = 2e-11
Identities = 45/150 (30%), Positives = 71/150 (47%), Gaps = 16/150 (10%)
Query: 860 VTFARSAIHNWGLYALEPIAAKEMIIEYVGESIRQPVAEMR--EKRYIKSGIGSSYLFRI 917
+ A + +G++A I E I EYVGE I + + R + + Y+ +
Sbjct: 539 IKLAATLCKGYGVFAKGQIEKDEYICEYVGEIIDKAEKKRRLDSVSISRDFQANHYMMEL 598
Query: 918 DENTVIDATKRGGIARFINHCCEPSCTAKIIKVDGRK---------RIVIYALRDIGTNE 968
+ +DA + G I+R+INH C+P+ + + KV +K R I A+R I +
Sbjct: 599 HKGLTVDAARYGNISRYINHSCDPNAASFVTKVFVKKTKEGSLYDTRSYIRAIRTIDDGD 658
Query: 969 ELTYDYKFERETDEGERLP-CLCGAPSCKG 997
E+T+ Y E E LP C CGA +C G
Sbjct: 659 EITFSYNMNNE----ENLPDCECGAENCMG 684
>SPBC428.08c_2 [BK] KOG1082 Histone H3 (Lys9) methyltransferase SUV39H1/Clr4
required for transcriptional silencing
Length = 364
Score = 69.3 bits (168), Expect = 3e-11
Identities = 49/165 (29%), Positives = 75/165 (44%), Gaps = 23/165 (13%)
Query: 856 RKKPVTFARSAIHNWGLYALEPIAAKEMIIEYVGESIRQPVAEMREKRYIKSGIGSSYLF 915
R P+ ++ WG+ +L A I Y+GE I A R+K Y GI +YLF
Sbjct: 200 RTLPLEIFKTKEKGWGVRSLRFAPAGTFITCYLGEVITSAEAAKRDKNYDDDGI--TYLF 257
Query: 916 RID-----ENTVIDATKRGGIARFINHCCEPSCTA-KIIKVDGRKRI---VIYALRDIGT 966
+D +DA G ++RF NH C P+ ++ G + I +A++DI
Sbjct: 258 DLDMFDDASEYTVDAQNYGDVSRFFNHSCSPNIAIYSAVRNHGFRTIYDLAFFAIKDIQP 317
Query: 967 NEELTYDY------------KFERETDEGERLPCLCGAPSCKGFL 999
EELT+DY K ++ R C CG+ +C+G+L
Sbjct: 318 LEELTFDYAGAKDFSPVQSQKSQQNRISKLRRQCKCGSANCRGWL 362
>At2g35160_2 [BK] KOG1082 Histone H3 (Lys9) methyltransferase SUV39H1/Clr4
required for transcriptional silencing
Length = 254
Score = 67.8 bits (164), Expect = 8e-11
Identities = 46/142 (32%), Positives = 68/142 (47%), Gaps = 19/142 (13%)
Query: 870 WGLYALEPIAAKEMIIEYVGESIRQPVAEMREKRYIKSGIGSSYLFRI---DENTVIDAT 926
WG+ +LE I I EY GE + AE + YLF + D+ I+A
Sbjct: 119 WGVRSLESIPIGSFICEYAGELLEDKQAESLTGK-------DEYLFDLGDEDDPFTINAA 171
Query: 927 KRGGIARFINHCCEPSCTAKIIKVDGRK----RIVIYALRDIGTNEELTYD--YKFERET 980
++G I RFINH C P+ A+ + D + I+ +AL +I +EL+YD YK ++
Sbjct: 172 QKGNIGRFINHSCSPNLYAQDVLYDHEEIRIPHIMFFALDNIPPLQELSYDYNYKIDQVY 231
Query: 981 DEGERLP---CLCGAPSCKGFL 999
D + C CG+ C G L
Sbjct: 232 DSNGNIKKKFCYCGSAECSGRL 253
>CE08681 [U] KOG4442 Clathrin coat binding protein/Huntingtin interacting
protein HIP1 involved in regulation of endocytosis
Length = 1590
Score = 67.4 bits (163), Expect = 1e-10
Identities = 40/133 (30%), Positives = 65/133 (48%), Gaps = 6/133 (4%)
Query: 871 GLYALEPIAAKEMIIEYVGESIRQPVAEMREKRYIKSGIGSSYLFRIDENTVIDATKRGG 930
GL A++ I IIEY+GE + + E R+ +Y + IDAT G
Sbjct: 683 GLRAVKDIKKGRFIIEYIGEVVERDDYEKRKTKYAADKKHKHHYLCDTGVYTIDATVYGN 742
Query: 931 IARFINHCCEPSCTAKIIKVDGR----KRIVIYALRDIGTNEELTYDYKFERETDEGERL 986
+RF+NH C+P+ + V R+ ++ R I EE+T+DY+F + ++
Sbjct: 743 PSRFVNHSCDPNAICEKWSVPRTPGDVNRVGFFSKRFIKAGEEITFDYQFVNYGRDAQQ- 801
Query: 987 PCLCGAPSCKGFL 999
C CG+ SC G++
Sbjct: 802 -CFCGSASCSGWI 813
>CE13601 [K] KOG1083 Putative transcription factor ASH1/LIN-59
Length = 1312
Score = 63.9 bits (154), Expect = 1e-09
Identities = 39/117 (33%), Positives = 59/117 (50%), Gaps = 9/117 (7%)
Query: 880 AKEMIIEYVGESIRQPVAEMREKRYIKSGIGSSYLFRIDENTVIDATKRGGIARFINHCC 939
A E + EY GE I + E ++++ + + I + +DATKR IARFI H C
Sbjct: 660 AGEFLCEYAGEVITR---EQAQEKFAQDR--DPRIIAIAAHLFVDATKRSNIARFIKHSC 714
Query: 940 EPSCTAKIIKVDGRKRIVIYALRDIGTNEELTYDYKFERETDEGERLPCLCGAPSCK 996
+P+ ++ V+G R ++AL D+ N E+T D D + C CGA CK
Sbjct: 715 KPNSRLEVWSVNGFYRAGVFALSDLNPNAEITVDKSDLLPFD----MACNCGATECK 767
>7290020 [BK] KOG1082 Histone H3 (Lys9) methyltransferase SUV39H1/Clr4
required for transcriptional silencing
Length = 1624
Score = 62.8 bits (151), Expect = 3e-09
Identities = 52/198 (26%), Positives = 80/198 (40%), Gaps = 26/198 (13%)
Query: 816 HNASSRLNRVFQRRFQQDIEAQRAAIGFE-SDLLSLNQL----------TKRKKPVTFAR 864
+ ASS+ + R D + A+ FE +D+ NQL T+ +
Sbjct: 1399 NGASSQNWYTAESRLNADFNYEDPAVIFECNDVCGCNQLSCKNRVVQNGTRTPLQIVECE 1458
Query: 865 SAIHNWGLYALEPIAAKEMIIEYVGESIRQPVAEMREKRYIKSGIGSSYLFRIDENTVID 924
WG+ AL + + Y GE + A+ R SY F +D ID
Sbjct: 1459 DQAKGWGVRALANVPKGTFVGSYTGEILTAMEADRRTD--------DSYYFDLDNGHCID 1510
Query: 925 ATKRGGIARFINHCCEPSCTAKIIKVDGR----KRIVIYALRDIGTNEELTYDY--KFER 978
A G + RF NH CEP+ + + + +I ++ RDI EE+ +DY KF R
Sbjct: 1511 ANYYGNVTRFFNHSCEPNVLPVRVFYEHQDYRFPKIAFFSCRDIDAGEEICFDYGEKFWR 1570
Query: 979 ETDEGERLPCLCGAPSCK 996
+ + C C +CK
Sbjct: 1571 -VEHRSCVGCRCLTTTCK 1587
>At3g03750 [BK] KOG1082 Histone H3 (Lys9) methyltransferase SUV39H1/Clr4
required for transcriptional silencing
Length = 354
Score = 61.6 bits (148), Expect = 6e-09
Identities = 50/168 (29%), Positives = 78/168 (45%), Gaps = 19/168 (11%)
Query: 851 NQLTKRKKPVTF--ARSAIHNWGLYALEPIAAKEMIIEYVGESIRQPVAEMREKRYIKSG 908
N++T++ V+ R W LYA + I + I EY GE + A R+ Y K
Sbjct: 182 NRVTQKGVSVSLKIVRDEKKGWCLYADQLIKQGQFICEYAGELLTTDEARRRQNIYDKLR 241
Query: 909 IGSSY---LFRIDENTV---------IDATKRGGIARFINHCCE-PSCTAKIIKVDGR-- 953
S+ L + E+ IDAT+ G +ARFINH C+ + + +++ G
Sbjct: 242 STQSFASALLVVREHLPSGQACLRINIDATRIGNVARFINHSCDGGNLSTVLLRSSGALL 301
Query: 954 KRIVIYALRDIGTNEELTYDYKFERETDEG--ERLPCLCGAPSCKGFL 999
R+ +A +DI EEL++ Y E ++L C CG+ C G L
Sbjct: 302 PRLCFFAAKDIIAEEELSFSYGDVSVAGENRDDKLNCSCGSSCCLGTL 349
>At2g22740_2 [BK] KOG1082 Histone H3 (Lys9) methyltransferase SUV39H1/Clr4
required for transcriptional silencing
Length = 294
Score = 61.2 bits (147), Expect = 8e-09
Identities = 47/173 (27%), Positives = 73/173 (42%), Gaps = 34/173 (19%)
Query: 857 KKPVTFARSAIHNWGLYALEPIAAKEMIIEYVGESIRQPVAEMR--EKRYIKSGIGSSY- 913
K P+ ++ WG+ L+ I I EYVGE + AE R Y+ IG+ Y
Sbjct: 119 KLPLEIFKTKSRGWGVRCLKSIPIGSFICEYVGELLEDSEAERRIGNDEYLFD-IGNRYD 177
Query: 914 -------------------LFRIDENT--VIDATKRGGIARFINHCCEPSCTAKIIKVDG 952
+ DE++ IDA +G + RFINH C P+ A+ + D
Sbjct: 178 NSLAQGMSELMLGTQAGRSMAEGDESSGFTIDAASKGNVGRFINHSCSPNLYAQNVLYDH 237
Query: 953 R----KRIVIYALRDIGTNEELTYDYKFERETDEG-----ERLPCLCGAPSCK 996
++ +A +I +EL YDY + + ++ PC CGA C+
Sbjct: 238 EDSRIPHVMFFAQDNIPPLQELCYDYNYALDQVRDSKGNIKQKPCFCGAAVCR 290
>7299871 [R] KOG1085 Predicted methyltransferase (contains a SET domain)
Length = 689
Score = 60.8 bits (146), Expect = 1e-08
Identities = 38/108 (35%), Positives = 52/108 (47%), Gaps = 4/108 (3%)
Query: 871 GLYALEPIAAKEMIIEYVGESIRQPVAEMREKRYIKSGIGSSYLFRIDENT---VIDAT- 926
G+ A P E ++EYVG+ I A REKRY Y++ + IDAT
Sbjct: 566 GVVADRPFKRNEFVVEYVGDLISIGEAAEREKRYALDENAGCYMYYFKHKSQQYCIDATV 625
Query: 927 KRGGIARFINHCCEPSCTAKIIKVDGRKRIVIYALRDIGTNEELTYDY 974
G + R INH + K++ + R +V+ A DI EELTYDY
Sbjct: 626 DTGKLGRLINHSRAGNLMTKVVLIKQRPHLVLLAKDDIEPGEELTYDY 673
>Hs6912652 [B] KOG1141 Predicted histone methyl transferase
Length = 1291
Score = 59.7 bits (143), Expect = 2e-08
Identities = 59/230 (25%), Positives = 92/230 (39%), Gaps = 23/230 (10%)
Query: 781 LAQPLNTVHNHQEQNFMAL---NGTESTNQEADLEQDNHNASSRLNRVFQRRFQ--QDIE 835
L +P + HQ + MA N + + E + + +SR Q +
Sbjct: 1073 LRRPPSKTSMHQSRRLMASAQSNPDDVLTLSSSTESEGESGTSRKPTAGQTSATAVDSDD 1132
Query: 836 AQRAAIGFESDLLS--LNQLTKRKKPVTFARSAIHNWGLYALEPIAAKEMIIEYVGESIR 893
Q + G E D N K+ V A + + L + IA K + V +
Sbjct: 1133 IQTISSGSEGDDFEDKKNMTGPMKRQV--AVKSTRGFALKSTHGIAIKSTNMASVDKGES 1190
Query: 894 QPVAEMREKRYIKSGIGSSYLFRIDENTVIDATKRGGIARFINHCCEPSCTAKIIKVDGR 953
PV + + Y G S Y +IDA G + R++NH C P+ + + VD
Sbjct: 1191 APVRKNTRQFY--DGEESCY--------IIDAKLEGNLGRYLNHSCSPNLFVQNVFVDTH 1240
Query: 954 KR----IVIYALRDIGTNEELTYDYKFERETDEGERLPCLCGAPSCKGFL 999
+ +A + I ELT+DY +E + EG+ L C CGA C+G L
Sbjct: 1241 DLRFPWVAFFASKRIRAGTELTWDYNYEVGSVEGKELLCCCGAIECRGRL 1290
>At5g13960_2 [BK] KOG1082 Histone H3 (Lys9) methyltransferase SUV39H1/Clr4
required for transcriptional silencing
Length = 296
Score = 58.5 bits (140), Expect = 5e-08
Identities = 49/172 (28%), Positives = 73/172 (41%), Gaps = 42/172 (24%)
Query: 864 RSAIHNWGLYALEPIAAKEMIIEYVGESIRQP-VAEMREKRYI----------------- 905
RSA W + + E I A + EY+G R V + + YI
Sbjct: 124 RSAKKGWAVRSWEYIPAGSPVCEYIGVVRRTADVDTISDNEYIFEIDCQQTMQGLGGRQR 183
Query: 906 ---------KSGIGSSYLFRIDENT---VIDATKRGGIARFINHCCEPSCTAKIIKVDGR 953
+G+ S DEN IDA G ARFINH CEP+ + + +
Sbjct: 184 RLRDVAVPMNNGVSQS---SEDENAPEFCIDAGSTGNFARFINHSCEPNLFVQCVLSSHQ 240
Query: 954 ----KRIVIYALRDIGTNEELTYDYKFERETDEG-----ERLPCLCGAPSCK 996
R+V++A +I +ELTYDY + ++ G ++L C CGA +C+
Sbjct: 241 DIRLARVVLFAADNISPMQELTYDYGYALDSVHGPDGKVKQLACYCGALNCR 292
>CE25069 [B] KOG1141 Predicted histone methyl transferase
Length = 1327
Score = 57.4 bits (137), Expect = 1e-07
Identities = 26/82 (31%), Positives = 45/82 (54%), Gaps = 4/82 (4%)
Query: 922 VIDATKRGGIARFINHCCEPSCTAKIIKVDGRKR----IVIYALRDIGTNEELTYDYKFE 977
VIDA +RG + RF+NH C+P+ + + D + + + + +ELT+DY++
Sbjct: 1243 VIDAKQRGNLGRFLNHSCDPNVHVQHVMYDTHDLRLPWVAFFTRKYVKAGDELTWDYQYT 1302
Query: 978 RETDEGERLPCLCGAPSCKGFL 999
++ +L C CGA +C G L
Sbjct: 1303 QDQTATTQLTCHCGAENCTGRL 1324
>At2g24740_2 [BK] KOG1082 Histone H3 (Lys9) methyltransferase SUV39H1/Clr4
required for transcriptional silencing
Length = 278
Score = 56.2 bits (134), Expect = 2e-07
Identities = 44/160 (27%), Positives = 69/160 (42%), Gaps = 32/160 (20%)
Query: 870 WGLYALEPIAAKEMIIEYVGES-IRQPVAEMREKRYIKSGIGSSYLFRIDEN-------- 920
WGL + +PI A I E+ G S ++ V E + + S I S+ + +
Sbjct: 116 WGLRSWDPIRAGTFICEFTGVSKTKEEVEEDDDYLFDTSRIYHSFRWNYEPELLCEDACE 175
Query: 921 -----------TVIDATKRGGIARFINHCCEPSCTAKIIKVDGRK-----RIVIYALRDI 964
+I A ++G + RF+NH C P+ + I+ D RI ++A++ I
Sbjct: 176 QVSEDANLPTQVLISAKEKGNVGRFMNHNCWPNVFWQPIEYDDNNGHIYVRIGLFAMKHI 235
Query: 965 GTNEELTYDYKFERETDEGE-------RLPCLCGAPSCKG 997
ELTYDY GE + CLCG+ C+G
Sbjct: 236 PPMTELTYDYGISCVEKTGEDEVIYKGKKICLCGSVKCRG 275
>Hs15042945 [R] KOG1085 Predicted methyltransferase (contains a SET domain)
Length = 393
Score = 53.9 bits (128), Expect = 1e-06
Identities = 31/108 (28%), Positives = 52/108 (47%), Gaps = 4/108 (3%)
Query: 871 GLYALEPIAAKEMIIEYVGESIRQPVAEMREKRYIKSGIGSSYLFR---IDENTVIDATK 927
G+ A + + ++EY G+ I A+ RE Y + Y++ + + +DAT+
Sbjct: 270 GVIATKQFSRGAFVVEYHGDLIEITDAKKREALYAQDPSTGCYMYYFQYLSKTYCVDATR 329
Query: 928 RGG-IARFINHCCEPSCTAKIIKVDGRKRIVIYALRDIGTNEELTYDY 974
+ R INH +C K+ +DG +++ A RDI EE YDY
Sbjct: 330 ETNRLGRLINHSKRGNCQTKLHDIDGVPHLILIASRDIAAGEEPLYDY 377
>At1g73100_2 [BK] KOG1082 Histone H3 (Lys9) methyltransferase SUV39H1/Clr4
required for transcriptional silencing
Length = 284
Score = 53.9 bits (128), Expect = 1e-06
Identities = 47/165 (28%), Positives = 73/165 (43%), Gaps = 41/165 (24%)
Query: 870 WGLYALEPIAAKEMIIEYVGE-----SIRQPVAEMREKRYI--KSGIGSSYLFR-----I 917
WGL + + + A I EY GE ++R E Y+ S + +S+ + +
Sbjct: 121 WGLRSWDSLRAGSFICEYAGEVKDNGNLR---GNQEEDAYVFDTSRVFNSFKWNYEPELV 177
Query: 918 DENT--------------VIDATKRGGIARFINHCCEPSCTAKIIKVDGRKRIVI----Y 959
DE+ +I A K G +ARF+NH C P+ + + +G VI +
Sbjct: 178 DEDPSTEVPEEFNLPSPLLISAKKFGNVARFMNHSCSPNVFWQPVIREGNGESVIHIAFF 237
Query: 960 ALRDIGTNEELTYDYKFERETD-------EGERLPCLCGAPSCKG 997
A+R I ELTYDY ++ G+R CLCG+ C+G
Sbjct: 238 AMRHIPPMAELTYDYGISPTSEARDESLLHGQR-TCLCGSEQCRG 281
>At1g17770_2 [BK] KOG1082 Histone H3 (Lys9) methyltransferase SUV39H1/Clr4
required for transcriptional silencing
Length = 288
Score = 53.9 bits (128), Expect = 1e-06
Identities = 41/160 (25%), Positives = 68/160 (41%), Gaps = 32/160 (20%)
Query: 870 WGLYALEPIAAKEMIIEYVG-ESIRQPVAEMREKRYIKSGIGSSY--------------- 913
WGL + +PI A I E+ G ++ V E + + S I +
Sbjct: 126 WGLRSWDPIRAGTFICEFAGLRKTKEEVEEDDDYLFDTSKIYQRFRWNYEPELLLEDSWE 185
Query: 914 ----LFRIDENTVIDATKRGGIARFINHCCEPSCTAKIIKVDGRKRIV----IYALRDIG 965
+ +I A ++G + RF+NH C P+ + I+ + R + ++A++ I
Sbjct: 186 QVSEFINLPTQVLISAKEKGNVGRFMNHSCSPNVFWQPIEYENRGDVYLLIGLFAMKHIP 245
Query: 966 TNEELTYDYKFE--RETDEGERL------PCLCGAPSCKG 997
ELTYDY ++E E L CLCG+ C+G
Sbjct: 246 PMTELTYDYGVSCVERSEEDEVLLYKGKKTCLCGSVKCRG 285
>Hs13994282 [B] KOG1141 Predicted histone methyl transferase
Length = 719
Score = 53.5 bits (127), Expect = 2e-06
Identities = 25/79 (31%), Positives = 41/79 (51%), Gaps = 4/79 (5%)
Query: 922 VIDATKRGGIARFINHCCEPSCTAKIIKVDGRKR----IVIYALRDIGTNEELTYDYKFE 977
++DATK G + RF+NH C P+ + + V+ R + + R + ELT+DY +E
Sbjct: 637 LLDATKEGNVGRFLNHSCCPNLLVQNVFVETHNRNFPLVAFFTNRYVKARTELTWDYGYE 696
Query: 978 RETDEGERLPCLCGAPSCK 996
T + + C CG C+
Sbjct: 697 AGTVPEKEIFCQCGVNKCR 715
>CE19602 [R] KOG1085 Predicted methyltransferase (contains a SET domain)
Length = 242
Score = 52.8 bits (125), Expect = 3e-06
Identities = 31/98 (31%), Positives = 50/98 (50%), Gaps = 5/98 (5%)
Query: 882 EMIIEYVGESIRQPVAEMREKRYIKSGIGSSYLFRIDENT---VIDATKRGGI-ARFINH 937
+ ++EY G + A++ E++Y SY++ + N IDATK R INH
Sbjct: 128 DFVVEYRGVMMEYSEAKVIEEQYSNDEEIGSYMYFFEHNNKKWCIDATKESPWKGRLINH 187
Query: 938 CC-EPSCTAKIIKVDGRKRIVIYALRDIGTNEELTYDY 974
P+ K++++DG +++ A R I EEL YDY
Sbjct: 188 SVLRPNLKTKVVEIDGSHHLILVARRQIAQGEELLYDY 225
>7291849 [B] KOG1141 Predicted histone methyl transferase
Length = 1262
Score = 51.6 bits (122), Expect = 6e-06
Identities = 28/88 (31%), Positives = 45/88 (50%), Gaps = 5/88 (5%)
Query: 914 LFRIDENT-VIDATKRGGIARFINHCCEPSCTAKIIKVDGRKR----IVIYALRDIGTNE 968
LF DE ++DA G + R+ NH C P+ + + VD + ++ I +
Sbjct: 1171 LFGKDEAPYIMDAKTTGNLGRYFNHSCSPNLFVQNVFVDTHDLRFPWVAFFSAAHIRSGT 1230
Query: 969 ELTYDYKFERETDEGERLPCLCGAPSCK 996
ELT++Y +E G+ L C CGAP+C+
Sbjct: 1231 ELTWNYNYEVGVVPGKVLYCQCGAPNCR 1258
>At4g15180 [BK] KOG1080 Histone H3 (Lys4) methyltransferase complex subunit SET1
and related methyltransferases
Length = 2351
Score = 51.2 bits (121), Expect = 8e-06
Identities = 24/53 (45%), Positives = 32/53 (60%)
Query: 922 VIDATKRGGIARFINHCCEPSCTAKIIKVDGRKRIVIYALRDIGTNEELTYDY 974
V+DA A I H C P+C AK+ VDG +I IY++R I EE+T+DY
Sbjct: 1818 VVDAMHMANYASRICHSCRPNCEAKVTAVDGHYQIGIYSVRAIEYGEEITFDY 1870
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.316 0.134 0.381
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 59,361,940
Number of Sequences: 60738
Number of extensions: 2599178
Number of successful extensions: 8006
Number of sequences better than 1.0e-05: 74
Number of HSP's better than 0.0 without gapping: 44
Number of HSP's successfully gapped in prelim test: 30
Number of HSP's that attempted gapping in prelim test: 7803
Number of HSP's gapped (non-prelim): 108
length of query: 1000
length of database: 30,389,216
effective HSP length: 116
effective length of query: 884
effective length of database: 23,343,608
effective search space: 20635749472
effective search space used: 20635749472
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)