ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI6490 good G KOG2504 Carbohydrate transport and metabolism Monocarboxylate transporter
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI6490 2257007 2258962 652
(652 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YNL125c [G] KOG2504 Monocarboxylate transporter 638 0.0
YKL221w [G] KOG2504 Monocarboxylate transporter 239 7e-63
YOL119c [G] KOG2504 Monocarboxylate transporter 108 3e-23
Hs4759120 [G] KOG2504 Monocarboxylate transporter 106 1e-22
Hs5730045 [G] KOG2504 Monocarboxylate transporter 97 6e-20
YOR306c [G] KOG2504 Monocarboxylate transporter 95 3e-19
Hs4759112 [G] KOG2504 Monocarboxylate transporter 91 7e-18
Hs22064599 [G] KOG2504 Monocarboxylate transporter 90 9e-18
7292012 [G] KOG2504 Monocarboxylate transporter 88 4e-17
CE21446 [G] KOG2504 Monocarboxylate transporter 87 8e-17
CE20478 [G] KOG2504 Monocarboxylate transporter 87 8e-17
Hs20559959 [G] KOG2504 Monocarboxylate transporter 87 1e-16
Hs18699730 [G] KOG2504 Monocarboxylate transporter 86 2e-16
7302291 [G] KOG2504 Monocarboxylate transporter 84 7e-16
7295764 [G] KOG2504 Monocarboxylate transporter 81 4e-15
Hs7019529 [G] KOG2504 Monocarboxylate transporter 80 1e-14
CE12336 [G] KOG2504 Monocarboxylate transporter 80 1e-14
Hs4759116 [G] KOG2504 Monocarboxylate transporter 78 5e-14
CE04864 [G] KOG2504 Monocarboxylate transporter 78 5e-14
CE29573 [G] KOG2504 Monocarboxylate transporter 76 1e-13
Hs4759118 [G] KOG2504 Monocarboxylate transporter 74 7e-13
7290288 [G] KOG2504 Monocarboxylate transporter 72 3e-12
Hs19923753 [G] KOG2504 Monocarboxylate transporter 70 8e-12
CE02803 [G] KOG2504 Monocarboxylate transporter 68 5e-11
7303213 [G] KOG2504 Monocarboxylate transporter 67 1e-10
CE05457 [G] KOG2504 Monocarboxylate transporter 63 2e-09
7303008 [G] KOG2504 Monocarboxylate transporter 63 2e-09
7299667 [G] KOG2504 Monocarboxylate transporter 60 1e-08
Hs4759114 [G] KOG2504 Monocarboxylate transporter 58 5e-08
7303562 [G] KOG2504 Monocarboxylate transporter 57 9e-08
7295260 [G] KOG4686 Predicted sugar transporter 57 1e-07
7303156 [G] KOG2504 Monocarboxylate transporter 56 2e-07
>YNL125c [G] KOG2504 Monocarboxylate transporter
Length = 673
Score = 638 bits (1645), Expect = 0.0
Identities = 338/675 (50%), Positives = 447/675 (66%), Gaps = 51/675 (7%)
Query: 8 TSEIDSISSASDVSHILSDPHGFVPKSKKSQLADSDQRITRRLSEPSSIKTADTGRSTII 67
+SE+ SI+S+ VS + VP S+ S K+ D R
Sbjct: 20 SSEVSSINSSQPVSFSKASIAAPVP-----------------CSDLHSTKSNDASRKL-- 60
Query: 68 TGISRTVTRTLSTIKKAVDDDNLQADNNTDDLNKLLERNFDIDDALRLTETAKRTDSRYX 127
ISRT+T L+ IKKAVDDDNLQ + N+ D+NK+LE FD+ DA+RL + S+
Sbjct: 61 -SISRTLTNRLNDIKKAVDDDNLQTEENSADVNKILESRFDVADAIRLQHN-ESVQSKLN 118
Query: 128 XXXXXXXXXXXXXXKGSDKWFDQTS--DSEGEYRSEVPVEL------------AGDD--- 170
S F +S + E+++ + +L +G D
Sbjct: 119 IPVTHTTTAGASLSAPSSSAFSASSIQNDTTEHKASMDSKLMRNRLYPASTKHSGKDLEA 178
Query: 171 --------EGQTLNKVFTNKETNTLDLPPEGGYGWVCCLCVTLVMFSTWGCNSAFGVFLA 222
+ T+ KVFTNK T L+LPP+GGYGWV CV L MFSTWGCN++FGV LA
Sbjct: 179 QGITEFEPDEPTVKKVFTNKSTGQLELPPDGGYGWVVTFCVFLTMFSTWGCNASFGVDLA 238
Query: 223 FYLNNSSFPGASKYDYALIAGMTVFFGQGLPPFVLLFMRIFGLKIPMYFGIVIMCLGFVL 282
+YLN+ ++PGASKYDYALIAG+TVF GQ L P V+ MRI GL+ M FG +M ++L
Sbjct: 239 YYLNHDTYPGASKYDYALIAGLTVFLGQLLSPLVMALMRIIGLRTTMLFGDAVMLAAYLL 298
Query: 283 ASYAVSLWQLYLTQGFLSGVGISFIFAPATTVLPGWFLKKRSFAMGLSLIGTGAGGVAYS 342
AS+ LWQLY+TQGF+ G IS IF PATTVLPGWFLKKR+ AMG+SL+GTGAGGV Y
Sbjct: 299 ASFTTKLWQLYVTQGFMVGCSISLIFVPATTVLPGWFLKKRAVAMGVSLLGTGAGGVVYG 358
Query: 343 LAVNKMIENTGNQRFALRILAITCSITCVVATLLLRQRVPMKATGIRNWKAIKQHCNDMF 402
LA NKM+ + GN R+ LRI+ I+CSI+ +VA LL++R P A G+++ +A+ + MF
Sbjct: 359 LATNKMLSDFGNTRWCLRIIGISCSISVLVAIALLKERNPTPAIGLKSPRAMFEQLKAMF 418
Query: 403 SMHIFKKWTVQLIAMWFMFALFGYTLMIFTLSSYAVANGLTAHQGSSLTAILNGAQSVGR 462
S+ + K V LIA+WFMFALF Y +M+FTLSSYA++ GL++H S+LTAILNG+QS+GR
Sbjct: 419 SLKVITKPFVVLIALWFMFALFAYNMMVFTLSSYAISKGLSSHDASTLTAILNGSQSIGR 478
Query: 463 PLIGYTGDKIGRTNITVMLTLLLTIFMFGFWIPADSYSSLIGFSICVGLCIGVANVMNTV 522
PL+G GDK GR N+T++LT LLTI+MF FWIPA ++ LI FSI VG C+GVANVMNTV
Sbjct: 479 PLMGLAGDKFGRANVTIVLTTLLTIYMFAFWIPAHTFVQLIFFSILVGSCVGVANVMNTV 538
Query: 523 LVADIVGPVDFLPAWGYVNLVGSPFMLVAEVIAQALT-EPNSNDPYLHTQIFAGCCFVAA 581
L+AD+V P +FLPAW +VN G+PF+LV EVIAQALT E + ++PYLH QIF GCCF+AA
Sbjct: 539 LIADMVKPEEFLPAWAFVNYCGAPFLLVCEVIAQALTVEKDKSNPYLHAQIFCGCCFIAA 598
Query: 582 LLLILGLREVTAKIKIKERQTINLQRLKDYD----DSNLSEKDNNILREREIKYDYLLGS 637
L+LI LRE + ++K+ ERQ + ++LK++ D++ +++D L+ER+ KYD LLG
Sbjct: 599 LILISILREYSIRMKLTERQAMTNEKLKEWKASEYDTDSADEDWGKLKERKTKYDLLLGP 658
Query: 638 GIKSYFARMFYPMHV 652
GIK YF RM YPM V
Sbjct: 659 GIKKYFLRMVYPMKV 673
>YKL221w [G] KOG2504 Monocarboxylate transporter
Length = 473
Score = 239 bits (611), Expect = 7e-63
Identities = 138/442 (31%), Positives = 234/442 (52%), Gaps = 11/442 (2%)
Query: 191 PEGGYGWVCCLCVTLVMFSTWGCNSAFGVFLAFYLNNSSFPGASKYDYALIAGMTVFFGQ 250
P+GGYGW L L FSTWG NS + ++LA YL N++F G SK DYA I G+ G
Sbjct: 36 PDGGYGWFILLAFILYNFSTWGANSGYAIYLAHYLENNTFAGGSKLDYASIGGLAFSCGL 95
Query: 251 GLPPFVLLFMRIFGLKIPMYFGIVIMCLGFVLASYAVSLWQLYLTQGFLSGVGISFIFAP 310
P + IF ++ + GI+ +LA+++V+LW++YLTQG L G G++FIF P
Sbjct: 96 FFAPVITWLYHIFSIQFIIGLGILFQGAALLLAAFSVTLWEIYLTQGVLIGFGLAFIFIP 155
Query: 311 ATTVLPGWFLKKRSFAMGLSLIGTGAGGVAYSLAVNKMIENTGNQRFALRILAITCSITC 370
+ T++P WF KRS A G+ G+G GG+ ++L + +++ G ++AL I C+
Sbjct: 156 SVTLIPLWFRNKRSLASGIGTAGSGLGGIVFNLGMQSILQKRG-VKWALIAQCIICTSLS 214
Query: 371 VVATLLLRQRVPMKATGIRNWKAIKQHCNDMFSMHIFKKWTVQLIAMWFMFALFGYTLMI 430
+A +L R G+R K + + ++ + + V L+ + FA+ GY +++
Sbjct: 215 TIALMLTR----TTHQGLRQHK--RSYKFELLDYDVLSNFAVWLLFGFVSFAMLGYVVLL 268
Query: 431 FTLSSYAVANGLTAHQGSSLTAILNGAQSVGRPLIGYTGDKIGRTNITVMLTLLLTIFMF 490
++LS + V+ G T+ QGS ++ +++ +GRP++G+ DK G + ++L L++ I +
Sbjct: 269 YSLSDFTVSLGYTSKQGSYVSCMVSVGSLLGRPIVGHIADKYGSLTVGMILHLVMAILCW 328
Query: 491 GFWIPADSYSSLIGFSICVGLCIGVANVMNTVLVADIVGPVDFLPAWGYVNLVGSPFMLV 550
WIP + ++ I F + VG +G +V IVG +G + + F LV
Sbjct: 329 AMWIPCKNLATAIRFGLLVGSIMGTIWPTIASIVTRIVGLQKLPGTFGSTWIFMAAFALV 388
Query: 551 AEVIAQAL--TEPNSNDPYLHTQIFAGCCFVAALLLILGLRE-VTAKIKIKERQTINLQR 607
A +I L T+ N ND Y T IF G + L LR + A+ +I R+ + +
Sbjct: 389 APIIGLELRSTDTNGND-YYRTAIFVGFAYFGVSLCQWLLRGFIIARDEIAVREAYSADQ 447
Query: 608 LKDYDDSNLSEKDNNILREREI 629
+ + + LS + R +++
Sbjct: 448 NELHLNVKLSHMSKCLFRYKQL 469
>YOL119c [G] KOG2504 Monocarboxylate transporter
Length = 501
Score = 108 bits (270), Expect = 3e-23
Identities = 81/332 (24%), Positives = 140/332 (41%), Gaps = 4/332 (1%)
Query: 269 MYFGIVIMCLGFVLASYAVSLWQLYLTQGFLSGVGISFIFAPATTVLPGWFLKKRSFAMG 328
M G VI G + S+WQ L SG+G + P + WFLK+R A
Sbjct: 168 MCTGTVIYAGGLFALANCKSVWQFILAFSVCSGLGTGILMTPLIGTVATWFLKRRGIATS 227
Query: 329 LSLIGTGAGGVAYSLAVNKMIENTGNQRFALRILAITCSITCVVATLLLRQRV-PMKATG 387
+S +G GG+ + + + K+ + G Q +A+RIL+ C + A++L R+R P+
Sbjct: 228 ISTMGGSIGGIVFPIMLRKLYKEVGFQ-WAIRILSFICLTCLICASVLARERTKPVVQPF 286
Query: 388 IRNWKAIKQHCNDMFSMHIFKKWTVQLIAMWFMFALFGYTLMIFTLSSYAVANGLTAHQG 447
+ K + + +F+ F + +A+ FA T L+SY++ G T +
Sbjct: 287 KSKAEVAKWYISSVFNWRYFLEGKFLFVAIGASFAESSLTSCATYLASYSMTRGNTENVA 346
Query: 448 SSLTAILNGAQSVGRPLIGYTGDK-IGRTNITVMLTLLLTIFMFGFWIPADSYSSLIGFS 506
++ N +GR + GY DK IGR N+ ++ + +F F W+P + ++
Sbjct: 347 YTMITASNAVGILGRYIPGYFADKFIGRFNVEIITISMAALFNFVMWLPFGGNTKVLWAY 406
Query: 507 ICV-GLCIGVANVMNTVLVADIVGPVDFLPAWGYVNLVGSPFMLVAEVIAQALTEPNSND 565
+C+ G G + V + I DF + V L+ + + I L +
Sbjct: 407 VCLWGFSTGSILSLTPVCIGQISKTTDFGKRYATVYLLQALVTIPVLPIGGTLIGKGTVA 466
Query: 566 PYLHTQIFAGCCFVAALLLILGLREVTAKIKI 597
Y H IF A + R + K+
Sbjct: 467 NYNHFIIFNSALMAAGAACYIISRHICVGAKL 498
>Hs4759120 [G] KOG2504 Monocarboxylate transporter
Length = 478
Score = 106 bits (265), Expect = 1e-22
Identities = 112/458 (24%), Positives = 197/458 (42%), Gaps = 38/458 (8%)
Query: 190 PPEGGYGWVCCLCVTLVMFSTWGCNSAFGVFLAFYLNNSSFPGASKY-DYALIAGMTVFF 248
PP+GG+GW+ V F + G + AF + + + Y + A I+ + +
Sbjct: 13 PPDGGWGWI----VVGAAFISIGFSYAFPKAVTVFFKEIQQIFHTTYSEIAWISSIMLAV 68
Query: 249 GQGLPPFVLLFMRIFGLKIPMYFGIVIMCLGFVLASYAVSLWQLYLTQGFLSGVGISFIF 308
P + + +G + + G ++ CLG VLAS++ S+ QLYLT GF++G+G++F
Sbjct: 69 MYAGGPVSSVLVNKYGSRPVVIAGGLLCCLGMVLASFSSSVVQLYLTMGFITGLGLAFNL 128
Query: 309 APATTVLPGWFLKKRSFAMGLSLIGTGAGGVAYSLA-VNKMIENTGNQRFALRILAITCS 367
PA T++ +F +KR A GL++ G+ SLA N+ + NT + + IL
Sbjct: 129 QPALTIIGKYFYRKRPMANGLAMAGSPV--FLSSLAPFNQYLFNTFGWKGSFLILGSLLL 186
Query: 368 ITCVVATLLLRQRVPMKATG-----------------IRNWKAIKQHCNDMFSMHIFKKW 410
CV + L+R P + T I+ K+ + N +FK
Sbjct: 187 NACVAGS-LMRPLGPNQTTSKSKNKTGKTEDDSSPKKIKTKKSTWEKVNKYLDFSLFKHR 245
Query: 411 TVQLIAMWFMFALFGYTLMIFTLSSYAVANGLTAHQGSSLTAILNGAQSVGRPLIG-YTG 469
+ + G+ I L+ YA G+ + + L +++ RP +G
Sbjct: 246 GFLIYLSGNVIMFLGFFAPIIFLAPYAKDQGIDEYSAAFLLSVMAFVDMFARPSVGLIAN 305
Query: 470 DKIGRTNITVMLTLLLTIFMFG----FWIP-ADSYSSLIGFSICVGLCIGVANVMNTVLV 524
K R I + + MF P A Y+SL+ +++ GL G + + +
Sbjct: 306 SKYIRPRIQYFFSFAI---MFNGVCHLLCPLAQDYTSLVLYAVFFGLGFGSVSSVLFETL 362
Query: 525 ADIVGPVDFLPAWGYVNLVGSPFMLVAEVIAQALTEPNSNDPYLHTQIFAGCCFVAALLL 584
D+VG F A G V +V +L+ +A L + Y++ + G VAA +
Sbjct: 363 MDLVGAPRFSSAVGLVTIVECGPVLLGPPLAGKLVDLTGEYKYMY--MSCGAIVVAASVW 420
Query: 585 ILGLREVTAKIKIKERQTINLQRLKDYDDSNLSEKDNN 622
+L + ++ KER+ N R K + LS+ ++
Sbjct: 421 LLIGNAINYRLLAKERKEEN-ARQKSRESEPLSKSKHS 457
>Hs5730045 [G] KOG2504 Monocarboxylate transporter
Length = 613
Score = 97.4 bits (241), Expect = 6e-20
Identities = 87/366 (23%), Positives = 148/366 (39%), Gaps = 23/366 (6%)
Query: 190 PPEGGYGWVCCLCVTLVMFSTWGCNSAFGVFLAFYLN-----NSSFPGASKYDYALIAGM 244
PPEGG+GWV T S +G +++ G+ + L N + + AL GM
Sbjct: 168 PPEGGFGWVVVFAATWCNGSIFGIHNSVGILYSMLLEEEKEKNRQVEFQAAWVGALAMGM 227
Query: 245 TVFFGQGLPPFVLLFMRIFGLKIPMYFGIVIMCLGFVLASYAVSLWQLYLTQGFLSGVGI 304
F P V +F G +I G + +G +S+ SL Y T G L G G
Sbjct: 228 IFFCS----PIVSIFTDRLGCRITATAGAAVAFIGLHTSSFTSSLSLRYFTYGILFGCGC 283
Query: 305 SFIFAPATTVLPGWFLKKRSFAMGLSLIGTGAGGVAYSLAVNKMIENTGNQRFALRILAI 364
SF F P+ +L +F ++ A G+ AG +S++ +I G++ + +
Sbjct: 284 SFAFQPSLVILGHYFQRRLGLANGV----VSAGSSIFSMSFPFLIRMLGDKIKLAQTFQV 339
Query: 365 TCSITCVVATLLLRQRVPMKAT-------GIRN-WKAIKQHCNDMFSMHIFKKWTVQLIA 416
+ V+ L L R + ++ G+R + F+M +F++ T ++ A
Sbjct: 340 LSTFMFVLMLLSLTYRPLLPSSQDTPSKRGVRTLHQRFLAQLRKYFNMRVFRQRTYRIWA 399
Query: 417 MWFMFALFGYTLMIFTLSSYAVANGLTAHQGSSLTAILNGAQSVGRPLIGYTGDKI-GRT 475
A GY + L Y + L + +GR + G+ D I G
Sbjct: 400 FGIAAAALGYFVPYVHLMKYVEEEFSEIKETWVLLVCIGATSGLGRLVSGHISDSIPGLK 459
Query: 476 NITVMLTLLLTIFMFGFWIP-ADSYSSLIGFSICVGLCIGVANVMNTVLVADIVGPVDFL 534
I + + L + + IP + LI + +GLC G + + ++VGP+
Sbjct: 460 KIYLQVLSFLLLGLMSMMIPLCRDFGGLIVVCLFLGLCDGFFITIMAPIAFELVGPMQAS 519
Query: 535 PAWGYV 540
A GY+
Sbjct: 520 QAIGYL 525
>YOR306c [G] KOG2504 Monocarboxylate transporter
Length = 521
Score = 95.1 bits (235), Expect = 3e-19
Identities = 90/410 (21%), Positives = 162/410 (38%), Gaps = 15/410 (3%)
Query: 191 PEGGY-GWVCCLCVTLVMFSTWGCNSAFGVFLAFYLNNSSFPGASKYDYALIAGMTVFFG 249
PEGG+ WV L + + +G ++ GV + +L ++ S + + +F
Sbjct: 100 PEGGFKAWVVTFGCFLGLIACFGLLNSTGV-IESHLQDNQLSSESVSTIGWLFSLFLFVC 158
Query: 250 QGLPPFVLLFMRIFGLKIPMYFGIVIMCLGFVLASYAVSLWQLYLTQGFLSGVGISFIFA 309
+ G + M G V G + + W L+ + G G + +
Sbjct: 159 SASCIISGTYFDRNGFRTIMIVGTVFHVAGLFATANSTKYWHFILSFAIVCGFGNGIVLS 218
Query: 310 PATTVLPGWFLKKRSFAMGLSLIGTGAGGVAYSLAVNKMI------ENTGNQRFALRILA 363
P +V +F K+R A+ ++ IG GGV + + + + T + +R L
Sbjct: 219 PLVSVPAHYFFKRRGTALAMATIGGSVGGVVFPIMLRSFFSMKSDTDPTYGFVWGIRTLG 278
Query: 364 ITCSITCVVATLLLRQRVPM----KATGIRNWKAI-KQHCNDMFSMHIFKKWTVQLIAMW 418
++ +L+++R+P G W+ I + + F F +
Sbjct: 279 FLDLALLTLSIILVKERLPHVIENSKDGESRWRYILRVYILQCFDAKAFLDMKYLFCVLG 338
Query: 419 FMFALFGYTLMIFTLSSYAVANGLTAHQGSSLTAILNGAQSVGRPLIGYTGDKIGRTNIT 478
+F+ + SYA ++G++A+ +L I+N GR + GY DK GR N+
Sbjct: 339 TVFSELSINSALTYYGSYATSHGISANDAYTLIMIINVCGIPGRWVPGYLSDKFGRFNVA 398
Query: 479 VMLTLLLTIFMFGFWIP-ADSYSSLIGFSICVGLCIGVANVMNTVLVADIVGPVDFLPAW 537
+ L L I MF W+P + +++ S G C G + V I +F +
Sbjct: 399 IATLLTLFIVMFVGWLPFGTNLTNMYVISALYGFCSGSVFSLLPVCCGQISKTEEFGKRY 458
Query: 538 GYVNLVGSPFMLVAEVIAQALTEPNSNDPYLHTQIFAG-CCFVAALLLIL 586
+ V LV I A+ + Y H IF+G FV+A+ I+
Sbjct: 459 STMYFVVGFGTLVGIPITGAIISIKTTADYQHYIIFSGLATFVSAVCYII 508
>Hs4759112 [G] KOG2504 Monocarboxylate transporter
Length = 465
Score = 90.5 bits (223), Expect = 7e-18
Identities = 95/402 (23%), Positives = 166/402 (40%), Gaps = 17/402 (4%)
Query: 191 PEGGYGWVCCLCVTLVMFSTWGCNSAFGVFLAFYLNNSSFPGASKYDYALIAGMTVFFGQ 250
P+GG+GW ++ ++ A VF + G D A I+ + +
Sbjct: 16 PDGGWGWAVLFGCFVITGFSYAFPKAVSVFFKELIQEF---GIGYSDTAWISSILLAMLY 72
Query: 251 GLPPFVLLFMRIFGLKIPMYFGIVIMCLGFVLASYAVSLWQLYLTQGFLSGVGISFIFAP 310
G P + + FG + M G + LG V AS+ S+ Q+YLT G ++G+G++ F P
Sbjct: 73 GTGPLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQVYLTTGVITGLGLALNFQP 132
Query: 311 ATTVLPGWFLKKRSFAMGLSLIGTGAGGVAYSLAVNKMIENTGNQRFALRILAITCSITC 370
+ +L +F K+R A GL+ G+ A S + +++++ R IL + C
Sbjct: 133 SLIMLNRYFSKRRPMANGLAAAGSPVFLCALS-PLGQLLQDRYGWRGGFLILG-GLLLNC 190
Query: 371 VVATLLLRQRVPMKATGIRNWKAIKQHCNDMFSMHIFKKWTVQLIAMWFMFALFGYTLMI 430
V L+R V G + + + +F+ L A+ + G +
Sbjct: 191 CVCAALMRPLVVTAQPG----SGPPRPSRRLLDLSVFRDRGFVLYAVAASVMVLGLFVPP 246
Query: 431 FTLSSYAVANGLTAHQGSSLTAILNGAQSVGRPLIGYTGDKIGRTNITVMLTLLLTIFMF 490
+ SYA G+ + + L IL RP G+ +G+ + ++F
Sbjct: 247 VFVVSYAKDLGVPDTKAAFLLTILGFIDIFARPAAGFVAG-LGKVRPYSVYLFSFSMFFN 305
Query: 491 GF----WIPADSYSSLIGFSICVGLCIGVANVMNTVLVADIVGPVDFLPAWGYVNLVGSP 546
G A Y L+ F I G+ G+ + ++ IVG F A G V L+ +
Sbjct: 306 GLADLAGSTAGDYGGLVVFCIFFGISYGMVGALQFEVLMAIVGTHKFSSAIGLVLLMEAV 365
Query: 547 FMLVAEVIAQALTEPNSNDPYLHTQIFAGC-CFVAALLLILG 587
+LV L + + Y++ I AG ++L+L+LG
Sbjct: 366 AVLVGPPSGGKLLD--ATHVYMYVFILAGAEVLTSSLILLLG 405
>Hs22064599 [G] KOG2504 Monocarboxylate transporter
Length = 579
Score = 90.1 bits (222), Expect = 9e-18
Identities = 93/408 (22%), Positives = 179/408 (43%), Gaps = 22/408 (5%)
Query: 190 PPEGGYGWVCCLCVTLVMFSTWGCNSAFGVFLAFYLNNSSFPGASKYDYALIAGMTVFFG 249
PP+GG+GWV + ++G + G LAF F +++ D A I+ + +
Sbjct: 140 PPDGGWGWVVAAAAFAINGLSYGLLRSLG--LAFPDLAEHFDRSAQ-DTAWISALALAVQ 196
Query: 250 QGLPPFVLLFMRIFGLKIPMYFGIVIMCLGFVLASYAVSLWQLYLTQGFLSGVGISFIFA 309
Q P +G + + G V+ LGFV +++A L LYL G L+G G + +FA
Sbjct: 197 QAASPVGSALSTRWGARPVVMVGGVLASLGFVFSAFASDLLHLYLGLGLLAGFGWALVFA 256
Query: 310 PATTVLPGWFLKKRSFAMGLSLIGTGAGGVAYSLAVNKMIENTGNQRFALRILAITCSIT 369
PA L +F ++R A+GL+L G GA + + A+ +++ G + L + AIT +T
Sbjct: 257 PALGTLSRYFSRRRVLAVGLALTGNGASSLLLAPALQLLLDTFGWRGALLLLGAITLHLT 316
Query: 370 CVVATLLLRQRVPMKATGIRNWKAIKQHCNDMFSMHIFKKWTVQLIAMWFMFALFGYTLM 429
A LL P+ G + A + + +F + + A+ GY +
Sbjct: 317 PCGALLL-----PLVLPG--DPPAPPRSPLAALGLSLFTRRAFSIFALGTALVGGGYFVP 369
Query: 430 IFTLSSYAVANGLTAHQGSSLTAILNGAQSVGRPLIGYTGDKIGRTNITVMLTLLLTIFM 489
L+ +A+ GL + + + A+ + R + G+ D+ G + +L + +
Sbjct: 370 YVHLAPHALDRGLGGYGAALVVAVAAMGDAGARLVCGWLADQ-GWVPLPRLLAVFGALTG 428
Query: 490 FGFWIPA--------DSYSS-LIGFSICVGLCIGVANVMNTVLVADIVGPVDFLPAWGYV 540
G W+ +S+ L+ ++ GL G + ++ +VG + A G V
Sbjct: 429 LGLWVVGLVPVVGGEESWGGPLLAAAVAYGLSAGSYAPLVFGVLPGLVGVGGVVQATGLV 488
Query: 541 NLVGSPFMLVAEVIAQALTEPNSNDPYLHTQIFAGCCFVAALLLILGL 588
++ S L+ ++ L + + + + + +G ++ + +GL
Sbjct: 489 MMLMSLGGLLGPPLSGFLRDETGD--FTASFLLSGSLILSGSFIYIGL 534
>7292012 [G] KOG2504 Monocarboxylate transporter
Length = 816
Score = 88.2 bits (217), Expect = 4e-17
Identities = 63/228 (27%), Positives = 105/228 (45%), Gaps = 11/228 (4%)
Query: 148 FDQT-SDSEGEYRSEVPVELAGDDEGQTLNKVFTNKETNT---LDLPPEGGYGWVCCLCV 203
F++T S+ E + + E + +DE N + E + L PP+GGYGWV C
Sbjct: 25 FERTDSELACEEAARLTAEQSPEDEDNQDNDEDDDDEESVYGELPPPPDGGYGWVICFAS 84
Query: 204 TLVMFSTWGCNSAFGVFLA-FYLNNSSFPGASKYDYALIAGMTVFFGQGLPPFVLLFMRI 262
+ G FG+FL F G + +L++G+ + G P V
Sbjct: 85 FMCNMIVDGIAYTFGIFLEEFVAYFHEGKGTVAWVGSLLSGVYLSAG----PIVSALANK 140
Query: 263 FGLKIPMYFGIVIMCLGFVLASYAVSLWQLYLTQGFLSGVGISFIFAPATTVLPGWFLKK 322
+G + G +I C+ FVL++++ ++ L T GF+ G G I+ PA + +F K
Sbjct: 141 YGCRAVCIAGSIIACIAFVLSTFSTNVSMLMATYGFMGGFGFGMIYLPAVVAVGYYFETK 200
Query: 323 RSFAMGLSLIGTGAGGVAYSLAVNKMIENTG--NQRFALRILAITCSI 368
RS A G+++ G+G G A++ ++E G N L + C+I
Sbjct: 201 RSLATGIAVCGSGFGTFAFAPLATYLLEEYGWKNALLIFAGLILNCAI 248
>CE21446 [G] KOG2504 Monocarboxylate transporter
Length = 666
Score = 87.0 bits (214), Expect = 8e-17
Identities = 55/201 (27%), Positives = 95/201 (46%), Gaps = 14/201 (6%)
Query: 190 PPEGGYGWVCCLCVTLVMFSTWG----CNSAFGVFLAFYLNNSSFPGASKYDYALIAGMT 245
PP+GGYGWV LV + G C A ++S GA +++ G
Sbjct: 39 PPDGGYGWVVVAASFLVNMAVDGVIYTCGKILVPIWADQFGSTSVAGAV---ISILTGCY 95
Query: 246 VFFGQGLPPFVLLFMRIFGLKIPMYFGIVIMCLGFVLASYAVSLWQLYLTQGFLSGVGIS 305
G P F+ +FG++ G ++ F+L+ +A ++W+LYL G L G+G
Sbjct: 96 YLAG----PLASSFVNVFGIRSVAIAGSILATTAFLLSRFASTIWELYLLFGVLGGIGFG 151
Query: 306 FIFAPATTVLPGWFLKKRSFAMGLSLIGTGAGGVAYSLAVNKMIENTGNQRFALRILAIT 365
++ P+ +L +F KKRS A G+++ G+G G + +S + + G + +
Sbjct: 152 CMYLPSIVILSTYFAKKRSVATGIAVCGSGIGTMVFSTINGPVFDYFGKDVGSFMVYLAA 211
Query: 366 CSITCVVATLLLRQRVPMKAT 386
+I+ + +LL P+KAT
Sbjct: 212 IAISGSLFSLLF---APLKAT 229
>CE20478 [G] KOG2504 Monocarboxylate transporter
Length = 571
Score = 87.0 bits (214), Expect = 8e-17
Identities = 55/201 (27%), Positives = 95/201 (46%), Gaps = 14/201 (6%)
Query: 190 PPEGGYGWVCCLCVTLVMFSTWG----CNSAFGVFLAFYLNNSSFPGASKYDYALIAGMT 245
PP+GGYGWV LV + G C A ++S GA +++ G
Sbjct: 39 PPDGGYGWVVVAASFLVNMAVDGVIYTCGKILVPIWADQFGSTSVAGAV---ISILTGCY 95
Query: 246 VFFGQGLPPFVLLFMRIFGLKIPMYFGIVIMCLGFVLASYAVSLWQLYLTQGFLSGVGIS 305
G P F+ +FG++ G ++ F+L+ +A ++W+LYL G L G+G
Sbjct: 96 YLAG----PLASSFVNVFGIRSVAIAGSILATTAFLLSRFASTIWELYLLFGVLGGIGFG 151
Query: 306 FIFAPATTVLPGWFLKKRSFAMGLSLIGTGAGGVAYSLAVNKMIENTGNQRFALRILAIT 365
++ P+ +L +F KKRS A G+++ G+G G + +S + + G + +
Sbjct: 152 CMYLPSIVILSTYFAKKRSVATGIAVCGSGIGTMVFSTINGPVFDYFGKDVGSFMVYLAA 211
Query: 366 CSITCVVATLLLRQRVPMKAT 386
+I+ + +LL P+KAT
Sbjct: 212 IAISGSLFSLLF---APLKAT 229
>Hs20559959 [G] KOG2504 Monocarboxylate transporter
Length = 426
Score = 86.7 bits (213), Expect = 1e-16
Identities = 90/400 (22%), Positives = 164/400 (40%), Gaps = 16/400 (4%)
Query: 190 PPEGGYGWVCCLCVTLVMFSTWGCNSAFGVFLAFYLNNSSFPGASKYDYALIAGMTVFFG 249
PP+GG+GWV L +G +FGVF ++ A + IA + +
Sbjct: 7 PPDGGWGWVVVLSAFFQSALVFGVLRSFGVFFVEFVAAFEEQAAR---VSWIASIGIAVQ 63
Query: 250 QGLPPFVLLFMRIFGLKIPMYFGIVIMCLGFVLASYAVSLWQLYLTQGFLSGVGISFIFA 309
Q P FG + + G ++ LG +LAS+A SL LYL+ G LSG G + FA
Sbjct: 64 QFGSPVGSALSTKFGPRPVVMTGGILAALGMLLASFATSLTHLYLSIGLLSGSGWALTFA 123
Query: 310 PATTVLPGWFLKKRSFAMGLSLIGTGAGGVAYSLAVNKMIENTGNQRFALRILAITCSIT 369
P L +F ++RS A GL+L G G ++ ++ + + L + A++ +
Sbjct: 124 PTLACLSCYFSRRRSLATGLALTGVGLSSFTFAPFFQWLLSHYAWRGSLLLVSALSLHLV 183
Query: 370 CVVATLLLRQRVPMKATGIRNWKAIKQHCNDMFSMHIFKKWTVQLIAMWFMFALFGYTLM 429
A L A G + + F ++TV L + GY +
Sbjct: 184 ACGALLRPPSLAEDPAVG-----GPRAQLTSLLHHGPFLRYTVALTLI-----NTGYFIP 233
Query: 430 IFTLSSYAVANGLTAHQGSSLTAILNGAQSVGRPLIGYTGDKI-GRTNITVMLTLLLTIF 488
L ++ + L +++ + VGR + G+ GD + G +ML LT
Sbjct: 234 YLHLVAHLQDLDWDPLPAAFLLSVVAISDLVGRVVSGWLGDAVPGPVTRLLMLWTTLTGV 293
Query: 489 MFGFWIPADSYSSLIGFSICVGLCIGVANVMNTVLVADIVGPVDFLPAWGYVNLVGSPFM 548
+ A + ++L+ ++ G G + ++ +++G G + ++ S
Sbjct: 294 SLALFPVAQAPTALVALAVAYGFTSGALAPLAFSVLPELIGTRRIYCGLGLLQMIESIGG 353
Query: 549 LVAEVIAQALTEPNSNDPYLHTQIFAGCCFVAALLLILGL 588
L+ ++ L + N Y + + AG ++ ++L L
Sbjct: 354 LLGPPLSGYLRDVTGN--YTASFVVAGAFLLSGSGILLTL 391
>Hs18699730 [G] KOG2504 Monocarboxylate transporter
Length = 515
Score = 85.5 bits (210), Expect = 2e-16
Identities = 100/424 (23%), Positives = 163/424 (37%), Gaps = 31/424 (7%)
Query: 152 SDSEGEYRSEVPVELAGDDEGQTLNKVFTNKETNTLDLPPEGGYGWVCCLCVTLVMFSTW 211
SDS +V VELAG E + PPEGG+GW+ L S +
Sbjct: 36 SDSPEAAVEKVEVELAGP----------ATAEPHEPPEPPEGGWGWLVMLAAMWCNGSVF 85
Query: 212 GCNSAFGVFLAFYLNNSSFPGASKYDY------ALIAGMTVFFGQGLPPFVLLFMRIFGL 265
G +A GV L K + +L GM F P V +F +FG
Sbjct: 86 GIQNACGVLFVSMLETFGSKDDDKMVFKTAWVGSLSMGMIFF----CCPIVSVFTDLFGC 141
Query: 266 KIPMYFGIVIMCLGFVLASYAVSLWQLYLTQGFLSGVGISFIFAPATTVLPGWFLKKRSF 325
+ G + +G + +S+ S+ LYLT G + G SF + P+ +L +F K+
Sbjct: 142 RKTAVVGAAVGFVGLMSSSFVSSIEPLYLTYGIIFACGCSFAYQPSLVILGHYFKKRLGL 201
Query: 326 AMGLSLIGTGAGGVAYSLAVNKMIENTGNQRFALRILAITCSITCV-------VATLLLR 378
G+ G+ + L + +I++ G + LR+L I + + +AT
Sbjct: 202 VNGIVTAGSSVFTILLPLLLRVLIDSVG-LFYTLRVLCIFMFVLFLAGFTYRPLATSTKD 260
Query: 379 QRVPMKATGIRNWKAIKQHCNDMFSMHIFKKWTVQLIAMWFMFALFGYTLMIFTLSSYAV 438
+ + + + K +F+ IFK + A+ ALFGY + L +
Sbjct: 261 KESGGSGSSLFSRKKFSPP-KKIFNFAIFKVTAYAVWAVGIPLALFGYFVPYVHLMKHVN 319
Query: 439 ANGLTAHQGSSLTAILNGAQSVGRPLIGYTGDKI-GRTNITVMLTLLLTIFMFGFWIPAD 497
+ + VGR L G D + G + + + I + IP
Sbjct: 320 ERFQDEKNKEVVLMCIGVTSGVGRLLFGRIADYVPGVKKVYLQVLSFFFIGLMSMMIPLC 379
Query: 498 S-YSSLIGFSICVGLCIGVANVMNTVLVADIVGPVDFLPAWGYVNLVGSPFMLVAEVIAQ 556
S + +LI + +GL G + + ++VG D A G++ S M V IA
Sbjct: 380 SIFGALIAVCLIMGLFDGCFISIMAPIAFELVGAQDVSQAIGFLLGFMSIPMTVGPPIAG 439
Query: 557 ALTE 560
L +
Sbjct: 440 LLRD 443
>7302291 [G] KOG2504 Monocarboxylate transporter
Length = 800
Score = 84.0 bits (206), Expect = 7e-16
Identities = 61/211 (28%), Positives = 97/211 (45%), Gaps = 7/211 (3%)
Query: 166 LAGDDEGQTLNKVFTNKETNTLDLPPEGGYGWVCCLCVTLVMFSTWGCNSAFGVFLAFYL 225
L ++ G +++ T K+T + P+GGYGWV +V G + +FG+ L
Sbjct: 17 LISNESGDSIDSSSTEKKTPKM---PDGGYGWVVVFASLVVSLIADGLSFSFGLINVELL 73
Query: 226 NNSSFPGASKYDYALIAGMTVFFGQGLPPFVLLFMRIFGLKIPMYFGIVIMCLGFVLASY 285
+ G S A I+ + + P + +G + G V+ GF L+S+
Sbjct: 74 E---YFGESTSKTAWISSLFFSVPLLMGPIWSNLVDKYGCRKMTILGGVVSAFGFALSSF 130
Query: 286 AVSLWQLYLTQGFLSGVGISFIFAPATTVLPGWFLKKRSFAMGLSLIGTGAGGVAYSLAV 345
S+ L +T G +SG+G+ + A + WF KKR+FA G+ GTG G Y+
Sbjct: 131 CNSIEMLMVTFGIISGLGLGIGYVTAVVSIAFWFDKKRTFATGIGASGTGIGTFVYARLT 190
Query: 346 NKMIENTGNQRFALRILAITCSITCVVATLL 376
+ +IE+ G R A IL T CV L+
Sbjct: 191 SYLIESYG-WRGATLILGGTMLNACVCGALM 220
>7295764 [G] KOG2504 Monocarboxylate transporter
Length = 1131
Score = 81.3 bits (199), Expect = 4e-15
Identities = 86/401 (21%), Positives = 165/401 (40%), Gaps = 43/401 (10%)
Query: 191 PEGGYGWVCCLCVTLVMFSTWGCNSAFGVFLAF---YLNNSS---FPGASKYDYALIAGM 244
P+GG+GW+ C LV T G ++G+ + YL+N+S GA + +++A
Sbjct: 411 PDGGWGWIICGVSFLVHILTTGLQLSYGLLWFYAVQYLHNTSGIELLGALSWSVSMVA-- 468
Query: 245 TVFFGQGLPPFVLLFMRIFGLKIPMYFGIVIMCLGFVLASYAVSLWQLYLTQGFLSGVGI 304
FV+ R +++ G ++M LG + S+A Q+ + G + GVG+
Sbjct: 469 --------TSFVVSLCRKRSIRLLSIVGGLVMPLGILFTSFATEFGQVVFSYGIVFGVGV 520
Query: 305 SFIFAPATTVLPGWFLKKRSFAMGLSLIGTGAGGVAYSLAVNKMIENTGNQRFALRILAI 364
+ + +T +L +F ++R F +++ G G G +S+ + + + G R L+I+A
Sbjct: 521 AMVREASTVMLGNYFKRRRQFVEMVAMSGEGVGIALFSVILKEGVGKAG-WRLGLQIVAA 579
Query: 365 TCSITCVVATLLLR------------QRVPMKATGIRNWKAIKQHCNDMFSMHIF----- 407
+++ + L+ R Q + + +R K I + + F
Sbjct: 580 LTALSFFMG-LMYRPASLYHPQRRAIQHLKNQRKKMREKKPILSQDVESTPKYFFLDISS 638
Query: 408 -KKWTVQLIAMWFMFALFGYTLMIFTLSSYAVANGLTAHQGSSLTAILNGAQSVGRPLIG 466
K TV+++ M A FG +F ++ A G + L L + ++G + G
Sbjct: 639 LKSVTVKILLMTSSVASFGIYTPMFLMALNAAEQGSDVQELVLLQTFLGISMALGVVIAG 698
Query: 467 YTGDK-------IGRTNITVMLTLLLTIFMFGFWIPADSYSSLIGFSICVGLCIGVANVM 519
+ + T I L L + F Y+ L S G+ +G
Sbjct: 699 ALLRRCFVIRHFVINTKIVTQLFLSIVALAILFLSFVMGYTGLCILSWLYGIGLGGFQYS 758
Query: 520 NTVLVADIVGPVDFLPAWGYVNLVGSPFMLVAEVIAQALTE 560
+L + + F AWG++ V S +L++ + L +
Sbjct: 759 LKILALERIKLKHFSKAWGFIRGVESVPVLISVPLTSFLND 799
>Hs7019529 [G] KOG2504 Monocarboxylate transporter
Length = 504
Score = 79.7 bits (195), Expect = 1e-14
Identities = 96/412 (23%), Positives = 161/412 (38%), Gaps = 52/412 (12%)
Query: 190 PPEGGYGWVCCLCVTLVMFSTWGCNSAFGVFLAFYLNNSSFPGASKYDYALIAGMTVFFG 249
PP+GG+GWV +V +G A VF + + A D A ++ + +
Sbjct: 12 PPDGGWGWVVLGACFVVTGFAYGFPKAVSVFFRALMRDFD---AGYSDTAWVSSIMLAML 68
Query: 250 QGLPPFVLLFMRIFGLKIPMYFGIVIMCLGFVLASYAVSLWQLYLTQGFLSGVGISFIFA 309
G P + + FG + M G ++ G +LAS+A L +LYLT G L+G+G++ F
Sbjct: 69 YGTGPVSSILVTRFGCRPVMLAGGLLASAGMILASFATRLLELYLTAGVLTGLGLALNFQ 128
Query: 310 PATTVLPGWFLKKRSFAMGLSLIGTGAGGVAYSLAVNKMIENTGNQRFAL---RILAITC 366
P+ +L +F ++R A GL+ G+ A S +++E G + L +L C
Sbjct: 129 PSLIMLGLYFERRRPLANGLAAAGSPVFLSALSPLGQQLLERFGWRGGFLLLGGLLLHCC 188
Query: 367 SITCVV------------------------------ATLLLRQRVPMKATGIRNWKAIKQ 396
+ V+ A L LR+ P W ++
Sbjct: 189 ACGAVMRPPPGPGPRPRRDSAGDRAGDAPGEAEADGAGLQLREASP--------WVRPRR 240
Query: 397 HCNDMFSMHIFKKWTVQLIAMWFMFALFGYTLMIFTLSSYAVANGLTAHQGSSLTAILNG 456
D+ ++ + + V + + M G + L +YA G+ + L +I+
Sbjct: 241 RLLDL-AVCTDRAFAVYAVTKFLM--ALGLFVPAILLVNYAKDAGVPDTDAAFLLSIVGF 297
Query: 457 AQSVGRPLIGYTGDKIGRTNITVMLTLLLTIFMFGFW----IPADSYSSLIGFSICVGLC 512
V RP G + R V L + G A SY +L+ F + GL
Sbjct: 298 VDIVARPACGALAG-LARLRPHVPYLFSLALLANGLTDLSSARARSYGALVAFCVAFGLS 356
Query: 513 IGVANVMNTVLVADIVGPVDFLPAWGYVNLVGSPFMLVAEVIAQALTEPNSN 564
G+ + ++ VG F A G V LV + +L+ A L + N
Sbjct: 357 YGMVGALQFEVLMAAVGAPRFPSALGLVLLVEAAAVLIGPPSAGRLVDALKN 408
>CE12336 [G] KOG2504 Monocarboxylate transporter
Length = 596
Score = 79.7 bits (195), Expect = 1e-14
Identities = 51/197 (25%), Positives = 93/197 (46%), Gaps = 6/197 (3%)
Query: 190 PPEGGYGWVCCLCVTLVMFSTWGCNSAFGVFL--AFYLNNSSFPGASKYDYALIAGMTVF 247
PP+GGYGW L+ G G L A+ + ++ ++++G F
Sbjct: 33 PPDGGYGWAIVAASFLLNMIVDGVIFTVGKILQPAWVHSFGISEASAAMTMSILSGCYFF 92
Query: 248 FGQGLPPFVLLFMRIFGLKIPMYFGIVIMCLGFVLASYAVSLWQLYLTQGFLSGVGISFI 307
G P + +FG + G +I LGF+L+ A +++ LY++ G ++G G +
Sbjct: 93 AG----PIASVLCNVFGCRQVALAGSLIAALGFLLSISAPNIYVLYVSFGLIAGAGFGMM 148
Query: 308 FAPATTVLPGWFLKKRSFAMGLSLIGTGAGGVAYSLAVNKMIENTGNQRFALRILAITCS 367
+ PA ++ +F KKRS A G+++ G+G G ++L + + + G + +
Sbjct: 149 YLPAIVIISQYFAKKRSVATGIAVCGSGIGTTVFALLNDVVWDFVGGDWKQFLVYTAAVT 208
Query: 368 ITCVVATLLLRQRVPMK 384
I+ + A +LLR P K
Sbjct: 209 ISGLGACILLRPLKPSK 225
>Hs4759116 [G] KOG2504 Monocarboxylate transporter
Length = 505
Score = 77.8 bits (190), Expect = 5e-14
Identities = 88/421 (20%), Positives = 166/421 (38%), Gaps = 41/421 (9%)
Query: 192 EGGYGWVCCLCVTLVMFSTWGCNSAFGVFLA-----FYLNNSSFPGASKYDYALIAGMTV 246
+G + WV L + T G + G+F F +NS + + +++ +
Sbjct: 9 DGSWAWVVLLATMVTQGLTLGFPTCIGIFFTELQWEFQASNSE----TSWFPSILTAVLH 64
Query: 247 FFGQGLPPFVLLFMRIFGLKIPMYFGIVIMCLGFVLASYAVSLWQLYLTQGFLSGVGISF 306
G P + + FG ++ + G V+ LG V +S++ +L QLY T GF++G+G+ F
Sbjct: 65 MAG----PLCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFITGLGMCF 120
Query: 307 IFAPATTVLPGWFLKKRSFAMGLSLIGTGAGGVAYSLAVNKMIENTGNQRFALRILAITC 366
F + TVL +F+++R A L+ +G G + L ++EN G + L I
Sbjct: 121 SFQSSITVLGFYFVRRRVLANALASMGVSLGITLWPLLSRYLLENLGWRGTFLVFGGI-- 178
Query: 367 SITCVVATLLLRQRVPMKATGIRN-----------------WKAIKQHCNDMFSMHIFKK 409
+ C + ++R A + + I++H H
Sbjct: 179 FLHCCICGAIIRPVATSVAPETKECPPPPPETPALGCLAACGRTIQRHLAFDILRHNTGY 238
Query: 410 WTVQLIAMWFMFALFGYTLMIFTLSSYAVANGLTAHQGSSLTAILNGAQSVGRPLIGYTG 469
L MW ++ G+ L L YA+ + + Q + L +I+ + RPL G
Sbjct: 239 CVYILGVMW---SVLGFPLPQVFLVPYAMWHSVDEQQAALLISIIGFSNIFLRPLAGLMA 295
Query: 470 DK---IGRTNITVMLTLLLTIFMFGFWIPADSYSSLIGFSICVGLCIGVANVMNTVLVAD 526
+ L LLL + + L+G+ + + + + ++ D
Sbjct: 296 GRPAFASHRKYLFSLALLLNGLTNLVCAASGDFWVLVGYCLAYSVSMSGIGALIFQVLMD 355
Query: 527 IVGPVDFLPAWGYVNLVGSPFMLVAEVIAQALTEPNSNDPYLHTQIFAGCCFVAALLLIL 586
IV F A G ++ L++ +A L + +N Y+ + F+ + L +
Sbjct: 356 IVPMDQFPRALGLFTVLDGLAFLISPPLAGLLLDATNNFSYV---FYMSSFFLISAALFM 412
Query: 587 G 587
G
Sbjct: 413 G 413
>CE04864 [G] KOG2504 Monocarboxylate transporter
Length = 556
Score = 77.8 bits (190), Expect = 5e-14
Identities = 45/170 (26%), Positives = 76/170 (44%), Gaps = 13/170 (7%)
Query: 189 LPPEGGYGWVCCLCVTLVMFSTWGCNSAFGVF-----LAFYLNNSSFPGASKYDYALIAG 243
LPP+GG+GWV + + G +FG+ + F NN+ +LI
Sbjct: 13 LPPDGGWGWVVVIGSFFIHVFADGFVYSFGILAEKLMIEFNSNNTMT--------SLIVS 64
Query: 244 MTVFFGQGLPPFVLLFMRIFGLKIPMYFGIVIMCLGFVLASYAVSLWQLYLTQGFLSGVG 303
M F G P +G +I G + +G +L+ +A +W ++ G + G+G
Sbjct: 65 MLTGFTLGAGPLASAVCNKYGCRITTIIGAGVAFVGCLLSCFATEIWHFVISVGVIMGIG 124
Query: 304 ISFIFAPATTVLPGWFLKKRSFAMGLSLIGTGAGGVAYSLAVNKMIENTG 353
++ PA ++ +F KRS A G+++ G G G V + +I N G
Sbjct: 125 FGLVYCPAIVIVTMYFESKRSLATGIAVAGAGVGAVVFGPINTFIISNYG 174
>CE29573 [G] KOG2504 Monocarboxylate transporter
Length = 594
Score = 76.3 bits (186), Expect = 1e-13
Identities = 50/176 (28%), Positives = 78/176 (43%), Gaps = 3/176 (1%)
Query: 189 LPPEGGYGWVCCLCVTLVMFSTWGCNSAFGVFLAFYLNNSSFPGASKYDYALIAGMTVFF 248
LPP+GG+GWV L V G +FGV + + AS ALI +
Sbjct: 16 LPPDGGWGWVVVLGSFFVHVFADGFVYSFGVLVETLMEEFH---ASNTMAALIISLLTGL 72
Query: 249 GQGLPPFVLLFMRIFGLKIPMYFGIVIMCLGFVLASYAVSLWQLYLTQGFLSGVGISFIF 308
G P +G +I G + +G L+ +A ++W + +T G + G G ++
Sbjct: 73 TLGSGPLASAVCNKYGCRITTITGAGVAFVGCALSYFATAMWHIVITVGVIMGTGFGLMY 132
Query: 309 APATTVLPGWFLKKRSFAMGLSLIGTGAGGVAYSLAVNKMIENTGNQRFALRILAI 364
PA ++ +F KRS A G+++ G G G V ++ I N G + L L I
Sbjct: 133 CPAIVIVTMYFENKRSLATGIAVAGAGVGTVLFAPINAFFINNYGWRSVFLAFLFI 188
Score = 60.1 bits (144), Expect = 1e-08
Identities = 52/218 (23%), Positives = 98/218 (44%), Gaps = 26/218 (11%)
Query: 399 NDMFSMHIFKKWTVQLIAMWFMFALFGYTLMIFTLSSYAVANGLTAHQGSSLTAILNGAQ 458
++M S+ + + T L A+ + G+ ++ L +A GL QGS + + +
Sbjct: 379 SNMLSLELLLEPTFLLFAISNLLTSVGFNSPLYFLPLHATKIGLEPIQGSKVLSAFGVSN 438
Query: 459 SVGRPLIGYTGD----------------KIGRTNITVMLTLLLTIFMFGF--WIPADSYS 500
+VGR + G D ++ NI++ + LLT+F + F +IP +YS
Sbjct: 439 TVGRIIFGVVADHKLPLPGGIGNDTARNRLWMYNISLTICGLLTVFCYQFNGFIPLATYS 498
Query: 501 SLIGFSICVGLCIGVANVMNTVLVADIVGPVDFLPAWGYVNLVGSPFMLVAEVIAQALTE 560
+L GFSI +C + +V++ D++G A+G + L + ++ L +
Sbjct: 499 ALFGFSIASYIC------LTSVILVDLLGLDKLTNAFGLLLLWQGVGTVFGPPVSGYLAD 552
Query: 561 PNSNDPYLHTQIFAGCCFVAALLLILGLREVTAKIKIK 598
N Y + +F G +A+ L++ G+ K K K
Sbjct: 553 MTGN--YTLSFVFCGVNLLASGLMLFGIPFFQKKAKAK 588
>Hs4759118 [G] KOG2504 Monocarboxylate transporter
Length = 523
Score = 73.9 bits (180), Expect = 7e-13
Identities = 53/205 (25%), Positives = 94/205 (45%), Gaps = 5/205 (2%)
Query: 174 TLNKVFTNKETNTLDLPPEGGYGWVCCLCVTLVMFSTWGCNSAFGVFLAFYLNNSSFPGA 233
T NK+ + N P+GG+GW + V T+G FGVF +++ +
Sbjct: 2 TQNKLKLCSKANVYTEVPDGGWGWAVAVSFFFVEVFTYGIIKTFGVFFNDLMDSFN---E 58
Query: 234 SKYDYALIAGMTVFFGQGLPPFVLLFMRIFGLKIPMYFGIVIMCLGFVLASYAVSLWQLY 293
S + I + VF P + FG ++ + G +++ G V AS++ + +Y
Sbjct: 59 SNSRISWIISICVFVLTFSAPLATVLSNRFGHRLVVMLGGLLVSTGMVAASFSQEVSHMY 118
Query: 294 LTQGFLSGVGISFIFAPATTVLPGWFLKKRSFAMGLSLIGTGAGGVAYSLAVNKMIENTG 353
+ G +SG+G F F P T+L +F K+RS ++ G A++ A+ + E G
Sbjct: 119 VAIGIISGLGYCFSFLPTVTILSQYFGKRRSIVTAVASTGECFAVFAFAPAIMALKERIG 178
Query: 354 NQRFALRILAITCSITCVVATLLLR 378
R++L + + + V+ LLR
Sbjct: 179 -WRYSLLFVGL-LQLNIVIFGALLR 201
>7290288 [G] KOG2504 Monocarboxylate transporter
Length = 715
Score = 72.0 bits (175), Expect = 3e-12
Identities = 48/190 (25%), Positives = 92/190 (48%), Gaps = 7/190 (3%)
Query: 190 PPEGGYGWVCCLCVTLVMFSTWGCNSAFGVFLAFYLNN-SSFPGASKYDYALIAGMTVFF 248
PP+GG+GWV ++ T G +FG+F +L+ + G + + +++ G+T
Sbjct: 117 PPDGGWGWVVVFGSFMIHIVTDGMTYSFGIFYNEFLDYFNEGKGYTAWIASIMVGVTFSS 176
Query: 249 GQGLPPFVLLFMRIFGLKIPMYFGIVIMCLGFVLASYAVSLWQLYLTQGFLSGVGISFIF 308
G P F+ +G + G ++ +++ +A ++ L +T GF +G+G I+
Sbjct: 177 G----PISSSFVNRYGCRAVTIAGSILAASCIIVSMFAQNVLTLIITIGFGTGLGFGLIY 232
Query: 309 APATTVLPGWFLKKRSFAMGLSLIGTGAGGVAYSLAVNKMIENTGNQRFALRILAITCSI 368
PA + +F KRS A G+++ G+G G ++ +I N G + L I I +
Sbjct: 233 LPAIVSVTQYFEAKRSLATGIAVCGSGFGTFVFAPLTEFLIGNYGWRGAMLIIGGIV--L 290
Query: 369 TCVVATLLLR 378
C++ + R
Sbjct: 291 NCIIFGAMFR 300
>Hs19923753 [G] KOG2504 Monocarboxylate transporter
Length = 500
Score = 70.5 bits (171), Expect = 8e-12
Identities = 104/491 (21%), Positives = 198/491 (40%), Gaps = 73/491 (14%)
Query: 190 PPEGGYGWVCCLCVTLVMFSTWGCNSAFGVFLA-FYLNNSSFPGASKYDYALIAGMTVFF 248
PP+GG+GW V + F + G + AF + F+ A+ + + I+ + +
Sbjct: 13 PPDGGWGWA----VVIGAFISIGFSYAFPKSITVFFKEIEGIFHATTSEVSWISSIMLAV 68
Query: 249 GQGLPPFVLLFMRIFGLKIPMYFGIVIMCLGFVLASYAVSLWQLYLTQGFLSGVGISFIF 308
G P + + +G +I M G + G + AS+ ++ QLY+ G + G+G++F
Sbjct: 69 MYGGGPISSILVNKYGSRIVMIVGGCLSGCGLIAASFCNTVQQLYVCIGVIGGLGLAFNL 128
Query: 309 APATTVLPGWFLKKRSFAMGLSLIGTGAGGVAYSLAVNKMIENTGNQRFALRILAITCSI 368
PA T++ +F K+R A GL++ G+ + +N++ R + IL +
Sbjct: 129 NPALTMIGKYFYKRRPLANGLAMAGSPV-FLCTLAPLNQVFFGIFGWRGSFLILG-GLLL 186
Query: 369 TCVVATLLLRQ--RVPMKA--------------TGIR-----------------NWKAIK 395
C VA L+R P KA +G++ +++
Sbjct: 187 NCCVAGALMRPIGPKPTKAGKDKSKASLEKAGKSGVKKDLHDANTDLIGRHPKQEKRSVF 246
Query: 396 QHCNDMFSMHIFKKWTVQLIAMWFMFALFGYTLMIFTLSSYAVANGLTAHQGSSLTAILN 455
Q N + +F L + FG + LSSY + ++ + + L +IL
Sbjct: 247 QTINQFLDLTLFTHRGFLLYLSGNVIMFFGLFAPLVFLSSYGKSQHYSSEKSAFLLSILA 306
Query: 456 GAQSVGRPLIGYTGD--------------KIGRTNITVMLTLLLTIFMFGFWIPADSYSS 501
V RP +G + + + ML L T ++ GF + Y+
Sbjct: 307 FVDMVARPSMGLVANTKPIRPRIQYFFAASVVANGVCHMLAPLSTTYV-GFCV----YAG 361
Query: 502 LIGFSICVGLCIGVANVMNTVLVADIVGPVDFLPAWGYVNLVGSPFMLVAEVIAQALTEP 561
GF+ G + + + D+VGP F A G V +V +L+ + L +
Sbjct: 362 FFGFA------FGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDM 415
Query: 562 NSNDPYLHTQIFAG-CCFVAALLLILGLREVTAKIKIKERQTINLQRLKDYDDS---NLS 617
+ Y +T G ++ + L +G+ + ++ KE Q N Q+ + ++ +++
Sbjct: 416 YGD--YKYTYWACGVVLIISGIYLFIGM-GINYRLLAKE-QKANEQKKESKEEETSIDVA 471
Query: 618 EKDNNILRERE 628
K N + + E
Sbjct: 472 GKPNEVTKAAE 482
>CE02803 [G] KOG2504 Monocarboxylate transporter
Length = 808
Score = 67.8 bits (164), Expect = 5e-11
Identities = 47/179 (26%), Positives = 80/179 (44%), Gaps = 7/179 (3%)
Query: 191 PEGGYGWVCCLCVTLVMFSTWGCNSAFGVFLAFYLNN-SSFPGASKYDYALIAGMTVFFG 249
P+GGYGWV + G ++AF F Y G + + +LI G + G
Sbjct: 84 PDGGYGWVIVFAAFMSNLVVDGISTAFSEFKQSYKERYQESDGLTVFIGSLIIGTYLLVG 143
Query: 250 QGLPPFVLLFMRIFGLKIPMYFGIVIMCLGFVLASYAVSLWQLYLTQGFLSGVGISFIFA 309
P V + + + G +I + F++A + +++ L G + G+G I+
Sbjct: 144 ----PLVSALCNKYEQRYVVMAGGLISGIAFMIAPASPNIYVFMLIYGVMGGLGFGMIYL 199
Query: 310 PATTVLPGWFLKKRSFAMGLSLIGTGAGGVAYSLAVNKMIENTGNQR--FALRILAITC 366
PA V+ +F KR+ A G+S+ G+G G L I N G Q+ + L ++ +C
Sbjct: 200 PAIVVVGFYFDSKRAMATGISVAGSGVGTFLVPLICQVCIANLGWQKTIWVLAVMIFSC 258
>7303213 [G] KOG2504 Monocarboxylate transporter
Length = 678
Score = 66.6 bits (161), Expect = 1e-10
Identities = 51/221 (23%), Positives = 100/221 (45%), Gaps = 32/221 (14%)
Query: 160 SEVPVELAGDDEGQTLNKVFTNKETNTLDLPPEGGYGWV-------CCLCVTLVMFSTWG 212
S+ P + ++EG+ E + +PP+ G+ WV CC + ++F +
Sbjct: 19 SKQPENIKEENEGEE------EIEEAAVVVPPDSGWAWVVMVASFLCCTVIDGIVFCSGL 72
Query: 213 CN----SAFGVFLAFYLNNSSFPGASKYDYALIAGMTVFFGQGLPPFVLLFMRIFGLKIP 268
+ FGV A+ SS L++G + G PFV FG +
Sbjct: 73 IQEQLMAEFGVSKAYVAFVSS----------LLSGCYLMAG----PFVSAMANRFGFRPV 118
Query: 269 MYFGIVIMCLGFVLASYAVSLWQLYLTQGFLSGVGISFIFAPATTVLPGWFLKKRSFAMG 328
G + + F L+ +A S+ L+L G L G+G ++ PA ++ +F K R+ A G
Sbjct: 119 TITGAIFAAICFGLSYFATSVEYLFLIYGVLGGIGFCMVYIPAVVIIGFYFEKWRALATG 178
Query: 329 LSLIGTGAGGVAYSLAVNKMIENTGNQRFALR-ILAITCSI 368
+++ G+G G ++ ++++ A++ I+ ++C++
Sbjct: 179 VAMCGSGVGTFVFAPLTKILLKSGWRYTLAIQGIIVLSCAL 219
>CE05457 [G] KOG2504 Monocarboxylate transporter
Length = 807
Score = 62.8 bits (151), Expect = 2e-09
Identities = 47/229 (20%), Positives = 95/229 (40%), Gaps = 8/229 (3%)
Query: 148 FDQTSDSEGEYRSEVPVELAGDDEGQTLNKVFTNKETNTLDLPPEGGYGWVCCLCVTLVM 207
F + + + + PV DD + T + +GGYGW+ L L+
Sbjct: 65 FSPSDEPRVRFEAPAPVSARSDDSDAESVESLTERPVYK-----DGGYGWLVVLASFLMH 119
Query: 208 FSTWGCNSAFGVFLAFYLNNSSFPGASKYDYALIAGMTVFFGQGLPPFVLLFMRIFGLKI 267
G + FG+ ++ ++ + A M + + P + I G ++
Sbjct: 120 AVCDGASFCFGIV---FVKIQEHFQCGRFVSMITASMFLSLPLIMSPVAGIVSDILGCRM 176
Query: 268 PMYFGIVIMCLGFVLASYAVSLWQLYLTQGFLSGVGISFIFAPATTVLPGWFLKKRSFAM 327
+ G I + ++A + ++ ++ G GVG+SFI+ A ++ +F K+R A
Sbjct: 177 SIIIGASICTVSCIIAMFCSHIFFFMISFGLGCGVGMSFIYNAAIVIVTYYFEKRRGLAT 236
Query: 328 GLSLIGTGAGGVAYSLAVNKMIENTGNQRFALRILAITCSITCVVATLL 376
++ GTG G V Y + +N + + +RI+ I ++ V ++
Sbjct: 237 SFAVSGTGVGTVIYPILLNLSMIYLASFVSDIRIILIFFAVMYFVIAVI 285
>7303008 [G] KOG2504 Monocarboxylate transporter
Length = 471
Score = 62.8 bits (151), Expect = 2e-09
Identities = 42/163 (25%), Positives = 65/163 (39%), Gaps = 3/163 (1%)
Query: 191 PEGGYGWVCCLCVTLVMFSTWGCNSAFGVFLAFYLNNSSFPGASKYDYALIAGMTVFFGQ 250
P+GGYGW+ V L+ + S FG L + ALI +
Sbjct: 10 PDGGYGWIVVAAVALINMTNQSILSVFGQLFVGELQKMQ---EDTFTAALITNLNSLALN 66
Query: 251 GLPPFVLLFMRIFGLKIPMYFGIVIMCLGFVLASYAVSLWQLYLTQGFLSGVGISFIFAP 310
F+ ++ F + G +++ LG L ++A W L F G G+ I
Sbjct: 67 FSGLFIGPAIKSFKPRNVAATGCILVALGLALCAFASESWHFILGYSFFVGFGLGLISPS 126
Query: 311 ATTVLPGWFLKKRSFAMGLSLIGTGAGGVAYSLAVNKMIENTG 353
+ +F KR A+G+SL G G G V V +++N G
Sbjct: 127 TFMAINSYFTTKRGRAVGVSLAGAGLGQVLIPHLVRYLLDNHG 169
>7299667 [G] KOG2504 Monocarboxylate transporter
Length = 571
Score = 60.1 bits (144), Expect = 1e-08
Identities = 86/396 (21%), Positives = 157/396 (38%), Gaps = 18/396 (4%)
Query: 190 PPEGGY-GWVCCLCVTLVMFSTWGCNSAFGVF---LAFYLNNSSFPGASKYDYALIAGMT 245
PP+GG W+ + L +G + +GV L L P AS ALI +
Sbjct: 32 PPDGGARAWLVMVSAFLCNGIIFGFINTYGVIHSLLTDRLTKLGDPEASS-KAALIGALA 90
Query: 246 VFFGQGLPPFVLLFMRIFGLKIPMYFGIVIMCLGFVLASYAV-SLWQLYLTQGFLSGVGI 304
+ GL++ + G V+ G +L+S+ ++ LY T G + G+G
Sbjct: 91 IGTTFLFSTMAGCLTDKIGLRLTTFAGGVLSAGGLLLSSFCTENIGALYFTYGIMFGLGA 150
Query: 305 SFIFAPATTVLPGWFLKKRSFAMGLSLIGTGAGGVAYSLAVNKMIENTGNQRFALRILAI 364
+ + P +L +F + G G+ V ++K++ + G + LRI+++
Sbjct: 151 ALAYTPTLAILGHYFKRYLGKVSGFVTAGSSVFTVILPPCLDKLLGSYGLEG-TLRIMSL 209
Query: 365 TCS--ITC--VVATLLLRQRVPMKATGIRNWKAIKQHCNDMFSMHIFKKWTVQLIAMWFM 420
+ I C V L P K G I + ++ I+K+ + A+
Sbjct: 210 VSAFIILCSFVYKPLHPPPEPPKKKPG---RSRINLFLRSIINVEIWKRKRFVIWALCVP 266
Query: 421 FALFGYTLMIFTLSSYAVANGLTAHQGSSLTAILNGAQSVGRPLIGYTGDKIGRTNITVM 480
ALFGY + + + V + + +GR + G D G + +
Sbjct: 267 LALFGYFVPYVHMMQF-VKTTFPGEDVNLPVMCIGITSGIGRLIFGVIADMPGVNRMYLQ 325
Query: 481 LTLLLTIFMFGFWIP-ADSYSSLIGFSICVGLCIGVANVMNTVLVADIVGPVDFLPAWGY 539
L++I + +P +SY L+ F++ +GL G + + +I GP A G+
Sbjct: 326 QLSLVSIGLVTLLLPLTNSYVILVSFTLVMGLFDGCFISLLGPIAYEICGPSGATQAIGF 385
Query: 540 VNLVGSPFMLVAEVIAQALTEPNSNDPYLHTQIFAG 575
+ + S + V +A + + S + Y I AG
Sbjct: 386 LLGLSSIPLTVGPPVAGMIFD--STNSYTLPLILAG 419
>Hs4759114 [G] KOG2504 Monocarboxylate transporter
Length = 487
Score = 57.8 bits (138), Expect = 5e-08
Identities = 41/152 (26%), Positives = 68/152 (43%), Gaps = 7/152 (4%)
Query: 184 TNTLDLPPEGGYGWVCCLCVTLVMFSTWGCNSAFGVFLAFYLNNSSFPGASKYDYALIAG 243
T TLD GG+GW+ + LV G F +F F + F G S+ I
Sbjct: 12 TKTLD----GGWGWMIVIHFFLVNVFVMGMTKTFAIF--FVVFQEEFEGTSE-QIGWIGS 64
Query: 244 MTVFFGQGLPPFVLLFMRIFGLKIPMYFGIVIMCLGFVLASYAVSLWQLYLTQGFLSGVG 303
+ P V + I G K G ++ G++++S+A S+ L +T G L G+G
Sbjct: 65 IMSSLRFCAGPLVAIICDILGEKTTSILGAFVVTGGYLISSWATSIPFLCVTMGLLPGLG 124
Query: 304 ISFIFAPATTVLPGWFLKKRSFAMGLSLIGTG 335
+F++ A V +F K+ + + ++ G G
Sbjct: 125 SAFLYQVAAVVTTKYFKKRLALSTAIARSGMG 156
>7303562 [G] KOG2504 Monocarboxylate transporter
Length = 596
Score = 57.0 bits (136), Expect = 9e-08
Identities = 37/124 (29%), Positives = 57/124 (45%), Gaps = 1/124 (0%)
Query: 252 LPPFVLLFMRIFGLKIPMYFGIVIMCLGFVLASYAVSLWQLYLTQGFLSGVGISFIFAPA 311
L P + F + ++ G + +G +L+ +A SL L LT G L+G+G P
Sbjct: 26 LAPLSSALCQRFSCRTVVFVGGIFCAMGMILSYFATSLLHLLLTFGVLTGIGGGLSTTPG 85
Query: 312 TTVLPGWFLKKRSFAMGLSLIGTGAGGVAYSLAVNKMIENTGNQRFALRILAITCSITCV 371
++ +F K R+ A G+ + GT AG + + + EN G L IL CV
Sbjct: 86 IVIVSQYFDKHRALANGICVSGTAAGSFILPVLIKHLAENCGFHGTIL-ILGGCMLHVCV 144
Query: 372 VATL 375
ATL
Sbjct: 145 SATL 148
>7295260 [G] KOG4686 Predicted sugar transporter
Length = 478
Score = 56.6 bits (135), Expect = 1e-07
Identities = 96/464 (20%), Positives = 192/464 (40%), Gaps = 51/464 (10%)
Query: 170 DEGQTLNKVFTNKETNTLDLPPEG-------GYGWVCCLCVTLVMFSTWGCNSAFGVFLA 222
+E Q +++ + N L LP G + ++ + + L+ F ++ C A G
Sbjct: 20 EEDQVVSRA--GRRDNELSLPSGGCCMPSSTSHRFMALVFMCLLGFGSYFCYDAPGALQN 77
Query: 223 FYLNNSSFPGASKYDYALIAGMTVFFGQGLPPFVLLFM------RIFGLKIPMYFGIVIM 276
++ + + A + LI + + P VL F+ R+FG+++ ++I+
Sbjct: 78 YFKKDLNLTSAQ---FTLIYSIYSW-----PNVVLCFVGGFLIDRLFGIRLGTIIYMMIL 129
Query: 277 CLG---FVLASYAVSLWQLYLTQGFLSGVGISFIFAPATTVLPGWFL-KKRSFAMGLSLI 332
+G F + W + L + F+ G+G + + WF K+ + GL L
Sbjct: 130 LVGQLIFACGGILDAFWMMILGR-FIFGIGAESLAVAQNSYAVLWFKGKELNMVFGLQLS 188
Query: 333 GTGAGGVAYSLAVNKMIENTGN---QRFALRILAITCSITCVVATL--LLRQRVPMKATG 387
G + + E N AL ++ + ++TCV++ L+ + +A
Sbjct: 189 VARFGSTVNFWVMQPIYEYVSNFYKGHTALGVVLLLATLTCVMSMTCALILGWMDKRAER 248
Query: 388 I--RNWKAIKQ--HCNDMFSMHIFKK--WTVQLIAMWFMFALFGYTLMIFTLSSYAVANG 441
I RN Q D+FS FK W V +I + + A+F + + + + G
Sbjct: 249 ILQRNNNPAGQIPKLTDVFS---FKPPFWMVSIICVAYYVAIFPFIAL--GQNFFVDRFG 303
Query: 442 LTAHQGSSLTAILNGAQSVGRPLIGYTGDKIGRTNITVMLTLLLTIFMFGFWIPADSYSS 501
L+ + +++ +++ +V P+ G+ DK+GR N+T + T LT + +
Sbjct: 304 LSPAEANTVDSLVYLIAAVSSPVFGFIIDKLGR-NVTWVFTATLTTIGAHALLTFTQLTP 362
Query: 502 LIGFSICVGLCIGVANVMNTVLVADIVGPVDFLPAWGYVNLVGSPFMLVAEVIAQALTEP 561
+G I +GL + LVA I+ A+G+ + + + V ++A + +
Sbjct: 363 YVGM-IIMGLSYSMLAASLWPLVALIIPEYQLGTAYGFCQSIQNLGLAVITIVAGIIVD- 420
Query: 562 NSNDPYLHTQIFAGCCFVAALLLILGLREVTAKIKIKERQTINL 605
+S ++ Q+F F+ L + L V K R +N+
Sbjct: 421 HSGGEHMWLQLF----FMGWLTIALISTGVIWAYNNKNRGNLNM 460
>7303156 [G] KOG2504 Monocarboxylate transporter
Length = 835
Score = 56.2 bits (134), Expect = 2e-07
Identities = 39/154 (25%), Positives = 67/154 (43%), Gaps = 3/154 (1%)
Query: 189 LPPEGGYGWVCCLCVTLVMFSTWGCNSAFGVFLAFYLNNSSFPGASKYDYALIAGMTVFF 248
+PP+GG+GWV + L G GV L + S + + +F
Sbjct: 297 IPPDGGFGWVIMVLSFLAQLIIDGLIFTIGVLLPSIAQDLDV-SISSVSFVASVQIGCYF 355
Query: 249 GQGLPPFVLLFMRIFGLKIPMYFGIVIMCLGFVLASYAVSLWQLYLTQGFLSGVGISFIF 308
G F + + FG + G++ + + +S++VSL L L G+ +S I+
Sbjct: 356 TSGA--FSAVLINRFGFRKVAIAGVLCSAVSILASSWSVSLTMLIFFYSVLGGITLSMIW 413
Query: 309 APATTVLPGWFLKKRSFAMGLSLIGTGAGGVAYS 342
A + ++ +F + R A G S G GAG V ++
Sbjct: 414 ASSQLIVGYYFERYRPMANGFSCSGGGAGIVLFT 447
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.323 0.138 0.416
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,730,370
Number of Sequences: 60738
Number of extensions: 1538075
Number of successful extensions: 4293
Number of sequences better than 1.0e-05: 32
Number of HSP's better than 0.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 4208
Number of HSP's gapped (non-prelim): 51
length of query: 652
length of database: 30,389,216
effective HSP length: 113
effective length of query: 539
effective length of database: 23,525,822
effective search space: 12680418058
effective search space used: 12680418058
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)