ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI6494 good Z KOG2000 Cytoskeleton Gamma-tubulin complex, DGRIP91/SPC98 component
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI6494 2261497 2259020 -826
(826 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YNL126w [Z] KOG2000 Gamma-tubulin complex DGRIP91/SPC98 component 487 e-137
Hs5453660 [Z] KOG2000 Gamma-tubulin complex DGRIP91/SPC98 component 129 1e-29
At5g06680 [Z] KOG2000 Gamma-tubulin complex DGRIP91/SPC98 component 117 6e-26
SPBC902.01c [Z] KOG2000 Gamma-tubulin complex DGRIP91/SPC98 comp... 110 9e-24
7292918 [Z] KOG2000 Gamma-tubulin complex DGRIP91/SPC98 component 99 2e-20
SPBC428.20c [Z] KOG2000 Gamma-tubulin complex DGRIP91/SPC98 comp... 92 4e-18
>YNL126w [Z] KOG2000 Gamma-tubulin complex DGRIP91/SPC98 component
Length = 846
Score = 487 bits (1254), Expect = e-137
Identities = 285/835 (34%), Positives = 471/835 (56%), Gaps = 24/835 (2%)
Query: 12 MLPASAGSAYSQQLIQDLYYSIKTSSKE--NVTKVLEYYKKIMVQRNQDMKSWSHLEMFA 69
+ P ++ Q + D+ +++S+K + ++++YK + + W +E F
Sbjct: 14 LAPQLLSQSHLQTFVSDVVNLLRSSTKSATQLGPLIDFYKLQSLDSPETTIMWHKIEKFL 73
Query: 70 GIMCHLSSPEEKHKYLLQCLSLLDKN--DELYDMREPMSKEVIENIQRKTTE----SVYA 123
+ + + ++ KYL SLL N ++ ++ E + N + + S+Y
Sbjct: 74 DALFGIQNTDDMVKYLSVFQSLLPSNYRAKIVQKSSGLNMENLANHEHLLSPVRAPSIYT 133
Query: 124 D-SFENFEKVSDRRSIGSYGGNAWQHSS--SDATLQSLSDPYFSTMVSRADIVKSIPYLV 180
+ SFEN ++ S+RRS+ S N + SS S TL+ LS+PY+ + DI+K + Y +
Sbjct: 134 EASFENMDRFSERRSMVS-SPNRYVPSSTYSSVTLRQLSNPYYVNTIPEEDILKYVSYTL 192
Query: 181 LGTPSTLFELKDKKFTIPSNIPNGESQQLHDIVEAGLLYLHLQIRVEYLKKHVTTSTLKV 240
L T S LF ++ IPS IPN ES LH I EAGLLY L +VE + + S +K
Sbjct: 193 LATTSALFPFDHEQIQIPSKIPNFESGLLHLIFEAGLLYQSLGYKVEKFRM-LNISPMKK 251
Query: 241 AFLTLIQSKLRDYSNFVNNFSSHLHPLDPLCFTYQHLYPEVLKLRTYMEYIENFEKSSAE 300
A + I +L++Y+ FVNN S + L Y+ +Y +++LR Y + E+ E+ S +
Sbjct: 252 ALIIEISEELQNYTAFVNNLVSS-GTVVSLKSLYREIYENIIRLRIYCRFTEHLEELSGD 310
Query: 301 GLLSVCQLQKSNGDPVLEKFASDALERLLQPYMKNICDWLIDGKLDSNVSSDFFVQNDEK 360
L + KS+GD + K A++ ++ Y + + +WL G L + F +N +
Sbjct: 311 TFLIELNIFKSHGDLTIRKIATNLFNSMISLYYEYLMNWLTKGLLRATYGEFFIAENTDT 370
Query: 361 EP--------LGLVFLPQKIPKFIPSLVAKKIYIIGKSLRYLEHCCSEVEWIGKFANKYS 412
+ + F +++P FIP +A KI++IGKS +LE C EV+W +F+ KY
Sbjct: 371 NGTDDDFIYHIPIEFNQERVPAFIPKELAYKIFMIGKSYIFLEKYCKEVQWTNEFSKKYH 430
Query: 413 LQYRLLG-PSMDHKFFELVNQQYGEINHYINTTLRSKFYYFETLNLLKDILLMGKSDVID 471
+ Y+ + FFE++N QY EI ++ N L KF+Y + + LK+ILLMGKSD +D
Sbjct: 431 VLYQSNSYRGISTNFFEIINDQYSEIVNHTNQILNQKFHYRDVVFALKNILLMGKSDFMD 490
Query: 472 SIIQNSENLFNQPSQLLESHHLTKCLQIAIQQSSLRNRLNKSDNNLLVNRLDARILELAH 531
++I+ + ++ PS L ++ LT+ LQ A+Q SSLR+ +N N+ ++N LDAR+L+L H
Sbjct: 491 ALIEKANDILATPSDSLPNYKLTRVLQEAVQLSSLRHLMNSPRNSSVINGLDARVLDLGH 550
Query: 532 GSSGWDVFTLDYLVDQPLSTVMDINQHGSRRDYLRIFNFLWRIKKNEYNYEQEWQKNSSI 591
GS GWDVFTLDY++ PLS V+++N+ R++YLRIFNFLWR KKN Y Y++E K++ I
Sbjct: 551 GSVGWDVFTLDYILYPPLSLVLNVNRPFGRKEYLRIFNFLWRFKKNNYFYQKEMLKSNDI 610
Query: 592 LKLFRKLNIRVPFIRDLLNKVSMINVLKNQIQSFTKKVETYCFESIIEHEFRKLLSNLNH 651
++ F+K+ P IRD++NK+S I++L+ Q Q F K+E+Y IIE F+++ L
Sbjct: 611 IRSFKKIRGYNPLIRDIINKLSRISILRTQFQQFNSKMESYYLNCIIEENFKEMTRKLQR 670
Query: 652 KDTDPTSSVKVKVLRNGVKVSSGVLKPDLHFIENFKELTTDDVSGYSSFDLEDLKRAHSV 711
+ + + L NG +G+L P + + + ++++L+ H+
Sbjct: 671 TENKSQNQFDLIRLNNGTIELNGILTPKAEVLTKSSSSKPQKHAIEKTLNIDELESVHNT 730
Query: 712 FLSNILNHPILYSG-SGASLGTYTHQLYPTTLVLLMDMSYEFVLNYSELNNVIHEICIQM 770
FL+NIL+H + + S S+G Y+ Q YPT+LVLL++ YEFV Y LN++ +EI I+M
Sbjct: 731 FLTNILSHKLFATNTSEISVGDYSGQPYPTSLVLLLNSVYEFVKVYCNLNDIGYEIFIKM 790
Query: 771 NLDPNQNLHDPIMRFNVISKKLVDQWKDFDNECNAYIKDLKWDENTEINKLSKIL 825
NL+ ++ + + +FN K++V Q+K+F + + DLK D + E+ LSK L
Sbjct: 791 NLNDHEASNGLLGKFNTNLKEIVSQYKNFKDRLYIFRADLKNDGDEELFLLSKSL 845
>Hs5453660 [Z] KOG2000 Gamma-tubulin complex DGRIP91/SPC98 component
Length = 907
Score = 129 bits (325), Expect = 1e-29
Identities = 118/505 (23%), Positives = 223/505 (43%), Gaps = 41/505 (8%)
Query: 167 VSRADIVKSIPYLVLGTPSTLFELKDKKFTIPSNIPNGESQQLHDIVE--AGLLYLHLQI 224
++ A +V+ I Y+ G ++ + + S+ L D + L +LH +I
Sbjct: 245 ITEAALVRDILYVFQGIDGKNIKMNNTENCYKVEGKANLSRSLRDTAVRLSELGWLHNKI 304
Query: 225 RVEYLKKHVTTSTLKV--AFLTLIQSKLRDYSNFVNNFSSHLHPLDPL--------CFTY 274
R ++ + S V +F + +LR+Y ++ S L D T
Sbjct: 305 RRYTDQRSLDRSFGLVGQSFCAALHQELREYYRLLSVLHSQLQLEDDQGVNLGLESSLTL 364
Query: 275 QHL----YPEVLKLRTYMEYIENFEKSSAEGLLSVCQLQKSNGDPVLEKFASDALERLLQ 330
+ L Y ++L+T +++ + L S GDP + L +
Sbjct: 365 RRLLVWTYDPKIRLKTLAALVDHCQGRKGGELASAVHAYTKTGDPYMRSLVQHILSLVSH 424
Query: 331 PYMKNICDWLIDGKLDSN-----VSSDFFVQNDEKEPLGLVFLPQKIPKFIPSLVAKKIY 385
P + + W+ DG+L+ V+SD V+ D IP F+ ++K+
Sbjct: 425 PVLSFLYRWIYDGELEDTYHEFFVASDPTVKTDRLWHDKYTLRKSMIPSFMTMDQSRKVL 484
Query: 386 IIGKSLRYLEHCCSE----VEWIGKFANKYSLQYRL-LGPSMDHKFFELVNQQYGEINHY 440
+IGKS+ +L C + + I + S Q L +++ F ++ Y E + Y
Sbjct: 485 LIGKSINFLHQVCHDQTPTTKMIAVTKSAESPQDAADLFTDLENAFQGKIDAAYFETSKY 544
Query: 441 INTTLRSKFYYFETLNLLKDILLMGKSDVIDSIIQNSENLFNQPSQLLESHHLTKCLQIA 500
+ L K+ + + ++ LL+G+ D I ++ + +P+ L H+LT L+ A
Sbjct: 545 LLDVLNKKYSLLDHMQAMRRYLLLGQGDFIRHLMDLLKPELVRPATTLYQHNLTGILETA 604
Query: 501 IQQSSLRNRLNKSDNNLLVNRLDARILELAHGSSGWDVFTLDYLVDQPLSTVMDINQHGS 560
++ ++ + D+ ++ RLD R+LE++ G +GWDVF+LDY VD P++TV
Sbjct: 605 VRATNAQ-----FDSPEILRRLDVRLLEVSPGDTGWDVFSLDYHVDGPIATVF---TREC 656
Query: 561 RRDYLRIFNFLWRIKKNEYNYEQEWQKNSSILKLFRKLNIRVPFIRDLLNKVSMINVLKN 620
YLR+FNFLWR K+ EY + + KL R + P +L++ ++L +
Sbjct: 657 MSHYLRVFNFLWRAKRMEYILTDIRKGHMCNAKLLRNM----PEFSGVLHQ---CHILAS 709
Query: 621 QIQSFTKKVETYCFESIIEHEFRKL 645
++ F +++ Y ++E + +L
Sbjct: 710 EMVHFIHQMQYYITFEVLECSWDEL 734
>At5g06680 [Z] KOG2000 Gamma-tubulin complex DGRIP91/SPC98 component
Length = 838
Score = 117 bits (294), Expect = 6e-26
Identities = 94/398 (23%), Positives = 168/398 (41%), Gaps = 23/398 (5%)
Query: 281 VLKLRTYMEYIENFEKSSAEGLLSVCQLQKSNGDPVLEKFASDALERLLQPYMKNICDWL 340
++K+R ++ + + L +GDP++ F L + P + + W+
Sbjct: 318 MVKMRLMAVLVDKCKVLRGGAMAGAIHLHAQHGDPLVHDFMMSLLRCVCSPLFEMVRSWV 377
Query: 341 IDGKLDSNVSSDFFVQNDEKEPL----GLVFLPQKIPKFIPSLVAKKIYIIGKSLRYLEH 396
++G+L+ F V K L G P +P FI +A++I GKS+ +L
Sbjct: 378 LEGELEDTFGEFFVVGQPVKVDLLWREGYKLHPAMLPSFISPSLAQRILRTGKSINFLRV 437
Query: 397 CCSEVEWI-----GKFANKYSLQYRLLGPSMDHKFFELVNQQYGEINHYINTTLRSKFYY 451
CC + W A+ + + LG LV + I+ ++ L ++ +
Sbjct: 438 CCDDHGWADAASEAAAASGTTTRRGGLGYGETDALEHLVTEAAKRIDKHLLDVLYKRYKF 497
Query: 452 FETLNLLKDILLMGKSDVIDSIIQNSENLFNQPSQLLESHHLTKCLQIAIQQSSLRNRLN 511
E +K LL+G+ D + ++ ++P+ + S L L+ AI+ S+ +
Sbjct: 498 KEHCLAIKRYLLLGQGDFVQYLMDIVGPKLSEPANNISSFELAGFLEAAIRASNAQY--- 554
Query: 512 KSDNNLLVNRLDARILELAHGSSGWDVFTLDYLVDQPLSTVMDINQHGSRRDYLRIFNFL 571
D+ +++RL +++ G GWDVF+L+Y PL TV YLR+FNFL
Sbjct: 555 --DDRDMLDRLRVKMMPHGSGDRGWDVFSLEYEARVPLDTVF---TESVLSKYLRVFNFL 609
Query: 572 WRIKKNEYNYEQEW---QKNSSILKLFRKLNIRVPFIRDLLNKVSMINVLKNQIQSFTKK 628
W++K+ E+ W + N F KL V LL+ + VL N++ F
Sbjct: 610 WKLKRVEHALIGIWKTMKPNCITSNSFVKLQSSVKL--QLLSALRRCQVLWNEMNHFVTN 667
Query: 629 VETYCFESIIEHEFRKLLSNLN-HKDTDPTSSVKVKVL 665
+ Y ++E + + KD D + K L
Sbjct: 668 FQYYIMFEVLEVSWSNFSKEMEAAKDLDDLLAAHEKYL 705
>SPBC902.01c [Z] KOG2000 Gamma-tubulin complex DGRIP91/SPC98 component
Length = 566
Score = 110 bits (275), Expect = 9e-24
Identities = 114/531 (21%), Positives = 226/531 (42%), Gaps = 63/531 (11%)
Query: 27 QDLYYSIKTSSKE-NVTKVL-EYYKKIMVQRNQDMKSWSHLEMFAGIMCHLSSPEEKHK- 83
Q++ +SI + + ++ +L + Y KI + N D + + ++ L S H
Sbjct: 38 QEIIHSISPDTFQLDIDDILYKIYSKIPPEENND----ALFSKLSNLVSRLKSQTVIHNK 93
Query: 84 ----YLLQCLSLLDKNDELYDMREPMSKEVIENIQRKTTESVYADSF--ENFEKVSDRRS 137
Y L LS + ++ D+ + E I N + V + +F +++V +
Sbjct: 94 SQILYFLYLLSPISQSSR--DVSSHLLDESISNPINIPSTEVESSNFGQTRYDQVPENPQ 151
Query: 138 IGSYGGN-------AWQHSSSDATLQSLSDPYFSTMVSRADIVKSIPYLVLGTPSTLFEL 190
I + + H SS + + T+++ AD++ SI Y++ G + +
Sbjct: 152 ITDWDEGLENESSISIAHDSSRLNRSTETSSVQHTLITEADLLSSISYVLQGISTEYVQF 211
Query: 191 KDKKFTIPSNIPNGESQQLHDIVEAGLLYLHLQIRVEY---LKKHVTTSTLKVAFLT--- 244
K++ + IP Q+ + E GLLY L++ Y + + + + AF+
Sbjct: 212 KNELALLSKRIPVQYLLQMRALSETGLLYQELKVFSNYDPSVSQSIDGDNVSKAFINDQS 271
Query: 245 -LIQSKLRDYSNFVNNFSSHLHPLD-----------PL-----CFTYQHLYPEVLKLRTY 287
+QS S + NF + + LD P+ C + + LKLR
Sbjct: 272 LALQSLKSVISKELTNFLALIASLDSQIRADASLEKPMVTIRRCIAWTQVAK--LKLRIL 329
Query: 288 MEYI-ENFEKSSAEGLLSVCQLQKSNGDPVLEKFASDALERLLQPYMKNICDWLIDGKLD 346
+ +N + + + L+ V +GDP++++ + L + P + I +W+ G+L
Sbjct: 330 SSVVNDNMNQENKKRLIQVVSKYNVHGDPLIQELSDKILTEITGPLYEMIENWIYKGELV 389
Query: 347 SNVSSDFFVQNDEKEP-----------LGLVFLPQK-IPKFIPSLVAKKIYIIGKSLRYL 394
F + + E G FL ++ IP F+ + KI++IGKSL +
Sbjct: 390 DPYQEFFVKEKNGSESHDHQGQGDVVWKGKYFLDKELIPSFLSEELVDKIFLIGKSLNFA 449
Query: 395 EHCCSEVEWIGKFANKYSLQYRLLGPSMDHKFFELVNQQYGEINHYINTTLRSKFYYFET 454
+ C + +W + K + P H +V++ Y E +++ + F+ +
Sbjct: 450 RYGCGDFDWAQEHYQKLVKKLSYRDP---HSLETVVDKAYTESINHLVYLMEEVFHLTDH 506
Query: 455 LNLLKDILLMGKSDVIDSIIQNSENLFNQPSQLLESHHLTKCLQIAIQQSS 505
L +K LL+G+ D +D ++++ N +QP+ L H+LT L+ AI+ S+
Sbjct: 507 LKAIKKYLLLGQGDFVDLLMESLGNSLDQPANTLFRHNLTASLESAIRSSN 557
>7292918 [Z] KOG2000 Gamma-tubulin complex DGRIP91/SPC98 component
Length = 917
Score = 99.4 bits (246), Expect = 2e-20
Identities = 80/356 (22%), Positives = 165/356 (45%), Gaps = 31/356 (8%)
Query: 312 NGDPVLEKFASDALERLLQPYMKNICDWLIDGKLDSNVSSDFFVQNDEKEPLGLVF---- 367
NG+ ++ K D L + P ++ I W+++G + S++ +FFV++ + + ++
Sbjct: 401 NGNDMVNKLVEDLLTAICGPLVRMISKWILEGGI-SDMHREFFVKSIKDVGVDRLWHDKF 459
Query: 368 ---LPQKIPKFIPSLVAKKIYIIGKSLRYLEHCCSEVEWIGK----FANKYSLQYRLLGP 420
LP +PKF+P +A KI + GKS+ +L C E + + S ++
Sbjct: 460 RLRLPM-LPKFVPMDMANKILMTGKSINFLREICEEQGMMKERDELMKVMESSASQIFSY 518
Query: 421 SMDHKFFELVNQQYGEINHYINTTLRSKFYYFETLNLLKDILLMGKSDVIDSIIQNSENL 480
+ D + V Y + + ++ + + L+ ++ LL+G+ D I +I+N +N
Sbjct: 519 TPDTSWHAAVETCYQQTSKHVLDIMVGPHKLLDHLHGMRRYLLLGQGDFISILIENMKNE 578
Query: 481 FNQPSQLLESHHLTKCLQIAIQQSSLRNRLNKSDNNLLVNRLDARILELAHGSSGWDVFT 540
+P + ++ LT L S+LR + D+ ++N LD + +G GW++ +
Sbjct: 579 LERPGLDIYANDLTSML-----DSALRCTNAQYDDPDILNHLDVIVQRPFNGDIGWNIIS 633
Query: 541 LDYLVDQPLSTVMDINQHGSRRDYLRIFNFLWRIKKNEYNYEQE-WQKNSSILKLFRKLN 599
L Y+V PL+ +++ + Y +F LWR+K E+ + W++ K R +
Sbjct: 634 LQYIVHGPLAAMLE----STMPTYKVLFKPLWRMKHMEFVLSMKIWKEQMGNAKALRTM- 688
Query: 600 IRVPFIRDLLNKVS-MINVLKNQIQSFTKKVETYCFESIIEHEFRKLLSNLNHKDT 654
+ + K S +N+ ++I F +++ Y +IE + +L + T
Sbjct: 689 ------KSEIGKASHRLNLFTSEIMHFIHQMQYYVLFEVIECNWVELQKKMQKATT 738
>SPBC428.20c [Z] KOG2000 Gamma-tubulin complex DGRIP91/SPC98 component
Length = 288
Score = 91.7 bits (226), Expect = 4e-18
Identities = 50/119 (42%), Positives = 76/119 (63%), Gaps = 9/119 (7%)
Query: 482 NQPSQLLESHHLTKCLQIAIQQSSLRNRLNKSDNNLLVNRLDARILELAHGSSGWDVFTL 541
+QP+ L H+LT L+ AI+ S+ + ++ RLDAR+LEL+HG +GWDVFTL
Sbjct: 1 DQPANTLFRHNLTASLESAIRSSNA-----SYEPEYVLKRLDARLLELSHGETGWDVFTL 55
Query: 542 DYLVDQPLSTVMDINQHGSRRDYLRIFNFLWRIKKNEYNYEQEWQK-NSSILKLFRKLN 599
+Y VD P++ + I + SR+ YL+IFNFLWR+K+ E+ W++ N +FR L+
Sbjct: 56 EYKVDSPINVI--ITPYCSRQ-YLKIFNFLWRLKRIEFALAHSWRRVNLGERNVFRNLD 111
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.319 0.136 0.394
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 50,511,141
Number of Sequences: 60738
Number of extensions: 2257688
Number of successful extensions: 6730
Number of sequences better than 1.0e-05: 6
Number of HSP's better than 0.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 6702
Number of HSP's gapped (non-prelim): 9
length of query: 826
length of database: 30,389,216
effective HSP length: 115
effective length of query: 711
effective length of database: 23,404,346
effective search space: 16640490006
effective search space used: 16640490006
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)