ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI6564 good KC KOG0025 Energy production and conversion Zn2+-binding dehydrogenase (nuclear receptor binding factor-1)
r_klactVI6564 good KC KOG0025 Transcription Zn2+-binding dehydrogenase (nuclear receptor binding factor-1)
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI6564 2284717 2283572 -382
(382 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YBR026c [KC] KOG0025 Zn2+-binding dehydrogenase (nuclear recepto... 485 e-137
SPAC26F1.04c [KC] KOG0025 Zn2+-binding dehydrogenase (nuclear re... 205 8e-53
Hs17445743 [KC] KOG0025 Zn2+-binding dehydrogenase (nuclear rece... 189 4e-48
Hs7705777 [KC] KOG0025 Zn2+-binding dehydrogenase (nuclear recep... 188 1e-47
7303260 [KC] KOG0025 Zn2+-binding dehydrogenase (nuclear recepto... 185 1e-46
At3g45770 [KC] KOG0025 Zn2+-binding dehydrogenase (nuclear recep... 172 7e-43
CE16575 [KC] KOG0025 Zn2+-binding dehydrogenase (nuclear recepto... 169 6e-42
CE19192 [KC] KOG0025 Zn2+-binding dehydrogenase (nuclear recepto... 127 3e-29
>YBR026c [KC] KOG0025 Zn2+-binding dehydrogenase (nuclear receptor binding
factor-1)
Length = 380
Score = 485 bits (1248), Expect = e-137
Identities = 233/361 (64%), Positives = 291/361 (80%), Gaps = 2/361 (0%)
Query: 24 FKSLIYSSHDSQDCTKVLKVHNYKPKKGSETSIVLKTLAFPINPSDINQLEGVYPSKPDK 83
FKSLIYS+H+ +DCTKVL V NY PK+ SIVLKTLAFPINPSDINQL+GVYPS+P+K
Sbjct: 20 FKSLIYSTHEVEDCTKVLSVKNYTPKQDLSQSIVLKTLAFPINPSDINQLQGVYPSRPEK 79
Query: 84 VTDYSTDEPSAIAGNEGVFEXXX--XXXXXXTLKPGDKVIPLQANFGTWSTYRTCDKESD 141
DYSTDEP+AIAGNEGVFE LK GD+VIPLQAN GTWS YR SD
Sbjct: 80 TYDYSTDEPAAIAGNEGVFEVVSLPSGSSKGDLKLGDRVIPLQANQGTWSNYRVFSSSSD 139
Query: 142 LIKIEGVDIYTAATVAVNGCTAYQLVNDYINWDPKGNDWLVQNAGTSSVSKIVTQIAKAK 201
LIK+ +D+++AATV+VNGCT +QLV+DYI+W+ GN+W++QNAGTSSVSKIVTQ+AKAK
Sbjct: 140 LIKVNDLDLFSAATVSVNGCTGFQLVSDYIDWNSNGNEWIIQNAGTSSVSKIVTQVAKAK 199
Query: 202 NINTLSVIRDRENFEEVAEILEKKYGATKVISETENGEKEFGKEVLPKVLGSNAQVKLAL 261
I TLSVIRDR+NF+EVA++LE KYGATKVISE++N +K F KEVL K+LG NA+V+LAL
Sbjct: 200 GIKTLSVIRDRDNFDEVAKVLEDKYGATKVISESQNNDKTFAKEVLSKILGENARVRLAL 259
Query: 262 NSVGGKSCANIARKLSKDGLMLTYGGMSKQPLTFPTGLFIFKGLKSHGFWVTENSKRDPE 321
NSVGGKS A+IARKL + LMLTYGGMSKQP+T PT L IFKGL S G+WVTE +K++P+
Sbjct: 260 NSVGGKSSASIARKLENNALMLTYGGMSKQPVTLPTSLHIFKGLTSKGYWVTEKNKKNPQ 319
Query: 322 NKIKTVNEVIELYRDGKIISPKEDIRALEWDVNNASDEEVLQLITDGIKTKGTKNMVILK 381
+KI T+++ I++Y G IISP+++I L W+ N +DE++L+L+ GI KG K MV+L+
Sbjct: 320 SKIDTISDFIKMYNYGHIISPRDEIETLTWNTNTTTDEQLLELVKKGITGKGKKKMVVLE 379
Query: 382 W 382
W
Sbjct: 380 W 380
>SPAC26F1.04c [KC] KOG0025 Zn2+-binding dehydrogenase (nuclear receptor binding
factor-1)
Length = 372
Score = 205 bits (522), Expect = 8e-53
Identities = 128/355 (36%), Positives = 200/355 (56%), Gaps = 14/355 (3%)
Query: 25 KSLIYSSHDSQDCTKVLKVHNYKPKKGSETSIVLKTLAFPINPSDINQLEGVYPSKPDKV 84
K++ YS + + +VL+ +Y K S+ + ++ LA PINPSDINQ++GVYPSKP
Sbjct: 22 KAIAYSEYGNPK--EVLRAVSYNVPKCSKNQVNVRFLASPINPSDINQIQGVYPSKPPFT 79
Query: 85 TDYSTDEPSAIAGNEGVFEXXXXXXXXX-TLKPGDKVIPLQANFGTWSTYRTCDKESDLI 143
D + +PSA+AGNEG+ E T PG I N G+W T D S L+
Sbjct: 80 NDVCSSKPSAVAGNEGLVEVVDVGDQFKGTFSPGQWAILGSVNLGSWRTEMNIDGRS-LV 138
Query: 144 KIEGV---DIYTAATVAVNGCTAYQLVNDYINWDPKGNDWLVQNAGTSSVSKIVTQIAKA 200
++ I AAT++VN CTAY L+ + + KG DW +Q+ S V Q+AK
Sbjct: 139 PVDKSAFPSIAEAATLSVNPCTAYCLLQHVVQLN-KG-DWFIQDGANSMVGIATIQLAKH 196
Query: 201 KNINTLSVIRDRENFEEVAEILEKKYGATKVISETENGEKEFGKEVLPKVLGSNAQVKLA 260
+++V+R+R + E++ E L K GAT VI++ E +++ K+ +P+ + +VKL
Sbjct: 197 FGYKSINVVRNRPDIEKLKEQL-KSLGATIVITDEELMDRKTMKQKVPEWI-QGGEVKLG 254
Query: 261 LNSVGGKSCANIARKLSKDGLMLTYGGMSKQPLTFPTGLFIFKGLKSHGFWVTENSKRDP 320
++ V G+ A +A+ +SK M T+GGMS+QPL P L IFK LK HGFWVT+ P
Sbjct: 255 IDCVSGRVAAEMAKYMSKGATMATFGGMSRQPLPVPVSLLIFKNLKFHGFWVTKWKSEHP 314
Query: 321 ENKIKTVNEVIELYRDGKIISPKEDIRALEWDVNNASDEEVLQLITDGIKTKGTK 375
E +K +++V + YR+G + + ++ +L+ D A ++ L + I+ G K
Sbjct: 315 EEFLKIIHKVEDFYRNGTLKTVNTELVSLKED---ADEKTFLDTFLNAIEGHGKK 366
>Hs17445743 [KC] KOG0025 Zn2+-binding dehydrogenase (nuclear receptor binding
factor-1)
Length = 373
Score = 189 bits (481), Expect = 4e-48
Identities = 117/326 (35%), Positives = 177/326 (53%), Gaps = 20/326 (6%)
Query: 18 SQESLKFKSLIYSSHDSQDCTKVLKVHNYKPKKGSETSIVLKTLAFPINPSDINQLEGVY 77
S E + ++L+Y H D KV+++ N + + + +K LA PINPSDIN ++G Y
Sbjct: 37 SAEPARVRALVYGHHG--DPAKVVELKNLELAAVRGSDVRVKMLAAPINPSDINMIQGNY 94
Query: 78 PSKPDKVTDYSTDEPSAIAGNEGVFEXXXXXXXXXTLKPGDKVIPLQANFGTWSTYRTCD 137
P E A+ GNEGV + LKPGD VIP A GTW T
Sbjct: 95 GFLP---------ELPAVGGNEGVAQVVAVGSNVTGLKPGDWVIPANAGLGTWRTEAVFS 145
Query: 138 KESDLIKIEGVDIYTAATVAVNGCTAYQLVNDYINWDPKGNDWLVQNAGTSSVSKIVTQI 197
+E+ + + + +AAT+ VN CTAY+++ D+ P D ++QNA S V + V QI
Sbjct: 146 EEALIQVPSDIPLQSAATLGVNPCTAYRMLMDFEQLQP--GDSVIQNASNSGVGQAVIQI 203
Query: 198 AKAKNINTLSVIRDRENFEEVAEILEKKYGATKVISETENGEKEFGKEVLPKVLGSNAQV 257
A A + T++V+RDR + +++++ L K GA VI+E E E + Q
Sbjct: 204 AAALGLRTINVVRDRPDIQKLSDRL-KSLGAEHVITEEELRRPE-----MKNFFKDMPQP 257
Query: 258 KLALNSVGGKSCANIARKLSKDGLMLTYGGMSKQPLTFPTGLFIFKGLKSHGFWVTENSK 317
+LALN VGGKS + R+L++ G M+TYGGM+KQP+ L IFK LK GFW+++ K
Sbjct: 258 RLALNCVGGKSSTELLRQLARGGTMVTYGGMAKQPVVASVSLLIFKDLKLRGFWLSQWKK 317
Query: 318 -RDPENKIKTVNEVIELYRDGKIISP 342
P+ + + + +L R G++ +P
Sbjct: 318 DHSPDQFKELILTLCDLIRRGQLTAP 343
>Hs7705777 [KC] KOG0025 Zn2+-binding dehydrogenase (nuclear receptor binding
factor-1)
Length = 373
Score = 188 bits (477), Expect = 1e-47
Identities = 116/326 (35%), Positives = 176/326 (53%), Gaps = 20/326 (6%)
Query: 18 SQESLKFKSLIYSSHDSQDCTKVLKVHNYKPKKGSETSIVLKTLAFPINPSDINQLEGVY 77
S E + + ++Y H D KV+++ N + + + +K LA PINPSDIN ++G Y
Sbjct: 37 SAEPARVRGVVYGHHG--DPAKVVELKNLELAAVRGSDVRVKMLAAPINPSDINMIQGNY 94
Query: 78 PSKPDKVTDYSTDEPSAIAGNEGVFEXXXXXXXXXTLKPGDKVIPLQANFGTWSTYRTCD 137
P E A+ GNEGV + LKPGD VIP A GTW T
Sbjct: 95 GLLP---------ELPAVGGNEGVAQVVAVGSNVTGLKPGDWVIPANAGLGTWRTEAVFS 145
Query: 138 KESDLIKIEGVDIYTAATVAVNGCTAYQLVNDYINWDPKGNDWLVQNAGTSSVSKIVTQI 197
+E+ + + + +AAT+ VN CTAY+++ D+ P D ++QNA S V + V QI
Sbjct: 146 EEALIQVPSDIPLQSAATLGVNPCTAYRMLMDFEQLQP--GDSVIQNASNSGVGQAVIQI 203
Query: 198 AKAKNINTLSVIRDRENFEEVAEILEKKYGATKVISETENGEKEFGKEVLPKVLGSNAQV 257
A A + T++V+RDR + +++++ L K GA VI+E E E + Q
Sbjct: 204 AAALGLRTINVVRDRPDIQKLSDRL-KSLGAEHVITEEELRRPE-----MKNFFKDMPQP 257
Query: 258 KLALNSVGGKSCANIARKLSKDGLMLTYGGMSKQPLTFPTGLFIFKGLKSHGFWVTENSK 317
+LALN VGGKS + R+L++ G M+TYGGM+KQP+ L IFK LK GFW+++ K
Sbjct: 258 RLALNCVGGKSSTELLRQLARGGTMVTYGGMAKQPVVASVSLLIFKDLKLRGFWLSQWKK 317
Query: 318 -RDPENKIKTVNEVIELYRDGKIISP 342
P+ + + + +L R G++ +P
Sbjct: 318 DHSPDQFKELILTLCDLIRRGQLTAP 343
>7303260 [KC] KOG0025 Zn2+-binding dehydrogenase (nuclear receptor binding
factor-1)
Length = 339
Score = 185 bits (469), Expect = 1e-46
Identities = 114/329 (34%), Positives = 178/329 (53%), Gaps = 24/329 (7%)
Query: 21 SLKFKSLIYSSHDSQDCTKVLKVHNYKPKKGSETSIVLKTLAFPINPSDINQLEGVYPSK 80
S+ KSL Y+ H +VL++ K + +++K LA PINP+DIN ++G YP K
Sbjct: 2 SVVAKSLKYTQHGEPQ--EVLQLVEDKLPDPKDNQVLVKILAAPINPADINTIQGKYPVK 59
Query: 81 PDKVTDYSTDEPSAIAGNEGVFEXXXXXXXXXTLKPGDKVIPLQANFGTWSTYRTCDKES 140
P + A+ GNE V E + G VIPL + GTW+T+ ++
Sbjct: 60 P---------KFPAVGGNECVAEVICVGDKVKGFEAGQHVIPLASGLGTWTTHAVYKEDQ 110
Query: 141 DLIKIEGVDIYTAATVAVNGCTAYQLVNDYINWDPKGNDWLVQNAGTSSVSKIVTQIAKA 200
LI + V + AAT VN TAY+++ D++ P D ++QN S+V + V Q+ +A
Sbjct: 111 LLIVSKKVGLAEAATSTVNPTTAYRMLKDFVQLCP--GDTVIQNGANSAVGQAVHQLCRA 168
Query: 201 KNINTLSVIRDRENFEEVAEILEKKYGATKVISETENGEKEFGKEVLPKVLGSNAQVKLA 260
IN++ ++RDR E+ ++L+ GAT+V++E E + K G + +LA
Sbjct: 169 WGINSVGIVRDRPEIAELKQMLQC-LGATEVLTEAEIRTSDIFKS------GKLKKPRLA 221
Query: 261 LNSVGGKSCANIARKLSKDGLMLTYGGMSKQPLTFPTGLFIFKGLKSHGFWVTENSKRD- 319
N VGGKS ++R L G+++TYGGMS++P+T TG IFK + GFW+T SK +
Sbjct: 222 FNCVGGKSATEVSRHLDNGGVLVTYGGMSREPVTVATGPLIFKDIAFRGFWMTRWSKENY 281
Query: 320 --PENKIKTVNEVIELYRDGKIISPKEDI 346
PE + K E+ EL GK ++P ++
Sbjct: 282 SSPE-RSKMFKEIFELMEQGKFVAPNHEM 309
>At3g45770 [KC] KOG0025 Zn2+-binding dehydrogenase (nuclear receptor binding
factor-1)
Length = 367
Score = 172 bits (436), Expect = 7e-43
Identities = 116/320 (36%), Positives = 169/320 (52%), Gaps = 36/320 (11%)
Query: 25 KSLIYSSHDSQDCTKVLKVHNYKPKKGSETSIVLKTLAFPINPSDINQLEGVYPSKPDKV 84
K+++Y H S D V ++ N P + E + +K +A PINPSDIN++EGVYP +P
Sbjct: 46 KAIVYEEHGSPD--SVTRLVNLPPVEVKENDVCVKMIAAPINPSDINRIEGVYPVRPPV- 102
Query: 85 TDYSTDEPSAIAGNEGVFEXXXXXXXXXTLKPGDKVIPLQANFGTWSTYRTCDKESDLIK 144
A+ G EGV E PGD VIP + GTW TY +ES K
Sbjct: 103 --------PAVGGYEGVGEVYAVGSNVNGFSPGDWVIPSPPSSGTWQTY-VVKEESVWHK 153
Query: 145 IEG-VDIYTAATVAVNGCTAYQLVNDYINWDPKGNDWLVQNAGTSSVSKIVTQIAKAKNI 203
I+ + AAT+ VN TA +++ D++N + D +VQN TS V + V Q+A+ + I
Sbjct: 154 IDKECPMEYAATITVNPLTALRMLEDFVNLN--SGDSVVQNGATSIVGQCVIQLARLRGI 211
Query: 204 NTLSVIRDRENFEEVAEILEKKYGATKVISETENGEKEFGKEVLPKVLGSNAQVKLALNS 263
+T+++IRDR +E E L K GA +V SE++ + G+ + L N
Sbjct: 212 STINLIRDRAGSDEAREQL-KALGADEVFSESQ-------------LNGNLPEPALGFNC 257
Query: 264 VGGKSCANIARKLSKDGLMLTYGGMSKQPLTFPTGLFIFKGLKSHGFWVTENSKRDPENK 323
VGG + + + + L + G M+TYGGMSK+P+T T FIFK L GFW+ K
Sbjct: 258 VGGNAASLVLKYLREGGTMVTYGGMSKKPITVSTTSFIFKDLALRGFWLQSWLSM---GK 314
Query: 324 IKTVNEVIE----LYRDGKI 339
+K E+I+ L RDGK+
Sbjct: 315 VKECREMIDYLLGLARDGKL 334
>CE16575 [KC] KOG0025 Zn2+-binding dehydrogenase (nuclear receptor binding
factor-1)
Length = 344
Score = 169 bits (428), Expect = 6e-42
Identities = 114/328 (34%), Positives = 175/328 (52%), Gaps = 27/328 (8%)
Query: 15 RAMSQESLKFKSLIYSSHDSQDCTKVLKVHNYKPKKGSETSIVLKTLAFPINPSDINQLE 74
R+ Q + + L+Y + + LK K ++ ++++ +A PINP+D+NQ++
Sbjct: 8 RSALQRAASTRQLVYEGYRNPPEAIQLKTVTIADKPSAD-QVLVQWIAAPINPADLNQIQ 66
Query: 75 GVYPSKPDKVTDYSTDEPSAIAGNEGVFEXXXXXXXXXTLKPGDKVIPLQANFGTWSTYR 134
GVYP KP A+ GNEG + ++K GD VIP ++ GTW
Sbjct: 67 GVYPVKPAL---------PAVGGNEGFGKVISVGSNVSSIKVGDHVIPDRSGLGTWRELG 117
Query: 135 TCDKESDLIKIEG-VDIYTAATVAVNGCTAYQLVNDYINWDPKGNDWLVQNAGTSSVSKI 193
+E+DL I+ + + AAT VN TAY+++ D+I D K D + QN S+V K
Sbjct: 118 L-HQENDLFPIDNTLSMEYAATFQVNPPTAYRMLKDFI--DLKKGDTVAQNGANSAVGKH 174
Query: 194 VTQIAKAKNINTLSVIRDRENFEEVAEILEKKYGATKVISETENGEKEFGKEVLPKVLGS 253
V QI + I T++V+R R+N EE+ + L K GA +VI++ E + K+ P V
Sbjct: 175 VIQICRILGIKTVNVVRSRDNLEELVKEL-KDLGADEVITQEELYSR---KKKFPGV--- 227
Query: 254 NAQVKLALNSVGGKSCANIARKLSKDGLMLTYGGMSKQPLTFPTGLFIFKGLKSHGFWVT 313
KLALN VGG+S +A L G M+TYGGMSKQP+ PTG IFK + GFW++
Sbjct: 228 ----KLALNCVGGRSSLFLASLLDHGGCMVTYGGMSKQPVDCPTGPLIFKDISLRGFWMS 283
Query: 314 E--NSKRDPENKIKTVNEVIELYRDGKI 339
+ ++ PE + + E+ + G+I
Sbjct: 284 RWYDIQKSPEKRHEMYQELAGWMKSGEI 311
>CE19192 [KC] KOG0025 Zn2+-binding dehydrogenase (nuclear receptor binding
factor-1)
Length = 346
Score = 127 bits (319), Expect = 3e-29
Identities = 103/337 (30%), Positives = 169/337 (49%), Gaps = 34/337 (10%)
Query: 19 QESLKFKSLIYSSHDSQDCTKVLKVHNYK-PKKGSETSIVLKTLAFPINPSDINQLEGVY 77
Q++++ ++LIY D KVL++ + P + +++ LA PINP DIN+++G Y
Sbjct: 2 QKTIRSQALIYRKFG--DPLKVLQLETVEVPAEPGSGECLVEWLASPINPLDINRIQGNY 59
Query: 78 PSKPDKVTDYSTDEPSAIAGNEGVFEXXXXXXXXXTLKPGDKVIPLQANFGTWSTYRTCD 137
+ E I G+EGV K GD V AN W+ + D
Sbjct: 60 AVRA---------ELPVIGGSEGVGRVVKAGSGSR-FKSGDHVTIFSANTPIWTEFGVVD 109
Query: 138 KESDLIKIEG-VDIYTAATVAVNGCTAYQLVNDYINWDPKGNDWLVQNAGTSSVSKIVTQ 196
+ +L+K++ + + AAT+ +N TA+ ++ Y+N KG D+++QN+ S V + V +
Sbjct: 110 -DDELVKLDNRIPLDLAATLMINPPTAWIMLKKYVNLQ-KG-DYIIQNSANSGVGRSVIE 166
Query: 197 IAKAKNINTLSVIRDRENFEEVAEILEKKYGATKVISETE--NGEKEFGKEVLPKVLGSN 254
+ KA +++++R+R+N E + L + GA V +E E ++F K + N
Sbjct: 167 MCKALGYKSINIVRNRQNIEALKTDLWR-IGADHVFTEEEFKGTSRQFLKSI-------N 218
Query: 255 AQVKLALNSVGGKSCANIARKLSKDGLMLTYGGMSKQPLTFPTGLFIFKGL----KSHGF 310
+ KLALN VGGKS I+ L + G +TYGGMSK+ F T +F + + G
Sbjct: 219 VRPKLALNGVGGKSALQISSVLERGGTCVTYGGMSKKAHEFTTSALVFNDICVRGVAVGM 278
Query: 311 WVTENSKRDPENKIKTVNEVIELYRDGKIIS-PKEDI 346
W + D N V+EV +L GKI + P E +
Sbjct: 279 WARQEEHLDEWN--LCVDEVQKLAVAGKITAIPMEKV 313
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.312 0.131 0.374
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,513,734
Number of Sequences: 60738
Number of extensions: 900805
Number of successful extensions: 2139
Number of sequences better than 1.0e-05: 8
Number of HSP's better than 0.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 2104
Number of HSP's gapped (non-prelim): 8
length of query: 382
length of database: 30,389,216
effective HSP length: 108
effective length of query: 274
effective length of database: 23,829,512
effective search space: 6529286288
effective search space used: 6529286288
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)