ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI6578 check: MH RT KOG0598 General function prediction only Ribosomal protein S6 kinase and related proteins
r_klactVI6578 check: MH RT KOG0598 Signal transduction mechanisms Ribosomal protein S6 kinase and related proteins
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI6578 2290613 2288946 -556
(556 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YBR028c [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 516 e-146
SPCC4G3.08 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 265 2e-70
Hs4506737 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 214 4e-55
YMR104c [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 208 2e-53
Hs4506739 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 207 3e-53
YKL126w [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 205 2e-52
7295426 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 199 7e-51
SPCC24B10.07 [RT] KOG0598 Ribosomal protein S6 kinase and relate... 196 8e-50
Hs5032091 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 193 7e-49
At3g08720 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 192 1e-48
At3g08730 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 189 7e-48
Hs20149547 [T] KOG0603 Ribosomal protein S6 kinase 186 6e-47
CE14798 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 186 1e-46
Hs5453976 [T] KOG0694 Serine/threonine protein kinase 185 2e-46
Hs4759050 [T] KOG0603 Ribosomal protein S6 kinase 185 2e-46
Hs19923570 [T] KOG0603 Ribosomal protein S6 kinase 185 2e-46
7300106 [T] KOG0690 Serine/threonine protein kinase 184 3e-46
CE22045 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 183 5e-46
At5g62310 [TR] KOG0606 Microtubule-associated serine/threonine k... 183 5e-46
Hs4502023 [T] KOG0690 Serine/threonine protein kinase 183 7e-46
Hs4506055 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 182 1e-45
7297542 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 182 2e-45
Hs4885549 [T] KOG0690 Serine/threonine protein kinase 181 3e-45
Hs7657526 [T] KOG0603 Ribosomal protein S6 kinase 181 3e-45
Hs14735945 [T] KOG0694 Serine/threonine protein kinase 181 3e-45
Hs4506057 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 179 1e-44
Hs20127541 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 179 1e-44
CE15475 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 179 1e-44
CE15473 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 179 1e-44
Hs4759052 [T] KOG0603 Ribosomal protein S6 kinase 178 2e-44
Hs4826948 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 178 2e-44
Hs5453970 [T] KOG0694 Serine/threonine protein kinase 177 3e-44
7302860 [T] KOG0696 Serine/threonine protein kinase 177 4e-44
At1g03920 [R] KOG0605 NDR and related serine/threonine kinases 177 5e-44
YPL203w [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 176 6e-44
YJL164c [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 176 6e-44
Hs4885061 [T] KOG0690 Serine/threonine protein kinase 176 6e-44
Hs15619015 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 176 8e-44
CE18169 [T] KOG0603 Ribosomal protein S6 kinase 176 8e-44
CE13014 [T] KOG0603 Ribosomal protein S6 kinase 176 1e-43
Hs20070247_2 [RT] KOG0598 Ribosomal protein S6 kinase and relate... 176 1e-43
Hs4506067 [T] KOG0696 Serine/threonine protein kinase 175 1e-43
CE29092 [T] KOG0694 Serine/threonine protein kinase 175 1e-43
SPBC106.10 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 175 2e-43
CE28760 [R] KOG0605 NDR and related serine/threonine kinases 175 2e-43
7295638 [T] KOG0603 Ribosomal protein S6 kinase 175 2e-43
CE04603 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 173 5e-43
At3g17850 [TR] KOG0606 Microtubule-associated serine/threonine k... 172 1e-42
Hs5453972 [T] KOG0694 Serine/threonine protein kinase 171 2e-42
At1g48490 [TR] KOG0606 Microtubule-associated serine/threonine k... 171 2e-42
CE02586 [T] KOG0696 Serine/threonine protein kinase 170 5e-42
YKL166c [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 169 8e-42
Hs4885563 [T] KOG0694 Serine/threonine protein kinase 169 1e-41
Hs20535816 [T] KOG0695 Serine/threonine protein kinase 169 1e-41
Hs10864650 [T] KOG0695 Serine/threonine protein kinase 169 1e-41
CE27166 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 168 2e-41
At3g23310 [R] KOG0605 NDR and related serine/threonine kinases 168 2e-41
CE18699 [T] KOG0694 Serine/threonine protein kinase 168 2e-41
7302861 [T] KOG0696 Serine/threonine protein kinase 168 2e-41
SPAC22E12.14c [RT] KOG0598 Ribosomal protein S6 kinase and relat... 167 3e-41
Hs4506071 [T] KOG0695 Serine/threonine protein kinase 167 5e-41
At1g45160 [TR] KOG0606 Microtubule-associated serine/threonine k... 166 7e-41
7301734 [T] KOG0694 Serine/threonine protein kinase 166 9e-41
At1g30640 [R] KOG0605 NDR and related serine/threonine kinases 165 1e-40
Hs13384594 [T] KOG0696 Serine/threonine protein kinase 165 2e-40
7303111 [T] KOG0695 Serine/threonine protein kinase 165 2e-40
At2g20470 [R] KOG0605 NDR and related serine/threonine kinases 164 3e-40
Hs22068916 [T] KOG0696 Serine/threonine protein kinase 164 4e-40
Hs20127450 [T] KOG0696 Serine/threonine protein kinase 164 4e-40
CE15612 [T] KOG0690 Serine/threonine protein kinase 164 4e-40
Hs10835065 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 163 6e-40
CE17354 [T] KOG0694 Serine/threonine protein kinase 163 6e-40
CE17353 [T] KOG0694 Serine/threonine protein kinase 163 6e-40
At5g09890 [R] KOG0605 NDR and related serine/threonine kinases 163 6e-40
At4g14350 [R] KOG0605 NDR and related serine/threonine kinases 163 6e-40
7303915 [T] KOG0694 Serine/threonine protein kinase 163 6e-40
7303914 [T] KOG0694 Serine/threonine protein kinase 163 6e-40
Hs4505695 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 162 9e-40
7294770 [T] KOG0603 Ribosomal protein S6 kinase 162 1e-39
YNR047w [R] KOG0610 Putative serine/threonine protein kinase 160 5e-39
YCR091w [R] KOG0610 Putative serine/threonine protein kinase 160 5e-39
Hs18579683 [R] KOG0605 NDR and related serine/threonine kinases 160 5e-39
SPBC12D12.04c [T] KOG0694 Serine/threonine protein kinase 160 6e-39
CE28744 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 159 1e-38
Hs6005814 [R] KOG0605 NDR and related serine/threonine kinases 159 1e-38
SPAC1B9.02c [RT] KOG0598 Ribosomal protein S6 kinase and related... 157 3e-38
7293735 [R] KOG0605 NDR and related serine/threonine kinases 157 3e-38
Hs4758666 [D] KOG0608 Warts/lats-like serine threonine kinases 157 4e-38
At4g33080 [R] KOG0605 NDR and related serine/threonine kinases 156 7e-38
YHR205w [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 155 1e-37
CE20493 [TR] KOG0606 Microtubule-associated serine/threonine kin... 155 1e-37
CE13844 [D] KOG0608 Warts/lats-like serine threonine kinases 155 1e-37
CE05274 [T] KOG0690 Serine/threonine protein kinase 155 1e-37
SPAC17G8.14c [T] KOG0694 Serine/threonine protein kinase 155 2e-37
At3g10540 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 155 2e-37
SPAC821.12 [R] KOG0605 NDR and related serine/threonine kinases 154 3e-37
Hs5453974 [T] KOG0694 Serine/threonine protein kinase 154 3e-37
Hs18959200 [D] KOG0608 Warts/lats-like serine threonine kinases 154 3e-37
At5g04510 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 154 3e-37
CE05507 [T] KOG0603 Ribosomal protein S6 kinase 154 4e-37
At2g19400 [R] KOG0605 NDR and related serine/threonine kinases 154 4e-37
7301971 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 153 6e-37
7294265 [TR] KOG0606 Microtubule-associated serine/threonine kin... 153 6e-37
SPCC417.06c [R] KOG0605 NDR and related serine/threonine kinases 153 8e-37
CE02604 [T] KOG0695 Serine/threonine protein kinase 153 8e-37
SPAC4G8.05 [R] KOG0610 Putative serine/threonine protein kinase 152 1e-36
Hs5453978 [T] KOG0614 cGMP-dependent protein kinase 152 1e-36
7301980 [D] KOG0608 Warts/lats-like serine threonine kinases 151 2e-36
Hs4506735 [T] KOG0603 Ribosomal protein S6 kinase 150 4e-36
Hs14149671 [TR] KOG0606 Microtubule-associated serine/threonine ... 149 8e-36
YBL105c [T] KOG0694 Serine/threonine protein kinase 149 1e-35
Hs4506073 [T] KOG0694 Serine/threonine protein kinase 148 2e-35
Hs14758219 [T] KOG0694 Serine/threonine protein kinase 148 2e-35
Hs20543401 [TR] KOG0606 Microtubule-associated serine/threonine ... 147 4e-35
Hs17455844 [TR] KOG0606 Microtubule-associated serine/threonine ... 147 4e-35
SPBC1861.09 [R] KOG0610 Putative serine/threonine protein kinase 147 5e-35
At2g45490 [D] KOG0580 Serine/threonine protein kinase 147 5e-35
Hs7019489 [T] KOG0694 Serine/threonine protein kinase 146 7e-35
Hs4885583 [T] KOG0612 Rho-associated coiled-coil containing prot... 146 7e-35
YNL161w [R] KOG0605 NDR and related serine/threonine kinases 146 9e-35
SPCC320.12c [D] KOG0580 Serine/threonine protein kinase 145 2e-34
Hs4507273 [D] KOG0580 Serine/threonine protein kinase 145 2e-34
ECU07g0520 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 145 2e-34
Hs4507275 [D] KOG0580 Serine/threonine protein kinase 144 3e-34
CE18646 [T] KOG0690 Serine/threonine protein kinase 144 3e-34
YOL100w [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 144 3e-34
Hs4759178 [D] KOG0580 Serine/threonine protein kinase 144 5e-34
Hs10835242 [T] KOG0614 cGMP-dependent protein kinase 144 5e-34
CE24761 [D] KOG0580 Serine/threonine protein kinase 144 5e-34
CE29298 [T] KOG0690 Serine/threonine protein kinase 143 6e-34
7301972 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 141 3e-33
SPBC4C3.11 [T] KOG0592 3-phosphoinositide-dependent protein kina... 140 4e-33
YDR466w [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 140 5e-33
SPAC24B11.11c [R] KOG0605 NDR and related serine/threonine kinases 140 5e-33
SPCC576.15c [T] KOG0592 3-phosphoinositide-dependent protein kin... 140 7e-33
7294566 [T] KOG0612 Rho-associated coiled-coil containing protei... 139 9e-33
Hs8923754 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 139 1e-32
Hs4759044 [T] KOG0612 Rho-associated coiled-coil containing prot... 139 1e-32
Hs20536595 [T] KOG0612 Rho-associated coiled-coil containing pro... 139 1e-32
Hs4885347 [T] KOG0986 G protein-coupled receptor kinase 138 2e-32
7299536 [D] KOG0580 Serine/threonine protein kinase 138 2e-32
YDR490c [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 138 3e-32
HsM4507279 [D] KOG0580 Serine/threonine protein kinase 137 4e-32
Hs4504101 [T] KOG0986 G protein-coupled receptor kinase 137 4e-32
Hs14196445 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 136 7e-32
CE21025 [D] KOG0580 Serine/threonine protein kinase 136 7e-32
Hs22066167 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 136 1e-31
Hs4506529 [T] KOG0986 G protein-coupled receptor kinase 135 1e-31
CE03492 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 135 1e-31
CE01554 [T] KOG0986 G protein-coupled receptor kinase 135 1e-31
Hs4502553 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 135 2e-31
CE03979 [T] KOG0614 cGMP-dependent protein kinase 134 3e-31
7302050 [T] KOG0986 G protein-coupled receptor kinase 134 4e-31
CE28739 [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 133 6e-31
Hs9966875 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 132 1e-30
Hs18552621 [R] KOG0597 Serine-threonine protein kinase FUSED 132 1e-30
CE19898 [T] KOG0614 cGMP-dependent protein kinase 132 1e-30
CE19897 [T] KOG0614 cGMP-dependent protein kinase 132 1e-30
CE08098 [T] KOG0612 Rho-associated coiled-coil containing protei... 131 3e-30
YGR092w [R] KOG0605 NDR and related serine/threonine kinases 130 5e-30
Hs4885055 [T] KOG0986 G protein-coupled receptor kinase 130 5e-30
Hs4501971 [T] KOG0986 G protein-coupled receptor kinase 130 5e-30
7297776 [D] KOG0580 Serine/threonine protein kinase 130 5e-30
Hs21166359 [T] KOG0986 G protein-coupled receptor kinase 130 7e-30
7299322 [R] KOG0611 Predicted serine/threonine protein kinase 130 7e-30
7293249 [T] KOG0612 Rho-associated coiled-coil containing protei... 129 9e-30
At4g24400 [T] KOG0583 Serine/threonine protein kinase 129 1e-29
At3g14370 [R] KOG0610 Putative serine/threonine protein kinase 129 2e-29
CE28740 [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 128 2e-29
7296166 [T] KOG0614 cGMP-dependent protein kinase 128 2e-29
CE27768 [R] KOG0586 Serine/threonine protein kinase 127 3e-29
CE23838 [R] KOG0586 Serine/threonine protein kinase 127 3e-29
7291742_1 [T] KOG0612 Rho-associated coiled-coil containing prot... 127 3e-29
Hs4885349 [T] KOG0986 G protein-coupled receptor kinase 127 4e-29
At4g32830 [D] KOG0580 Serine/threonine protein kinase 127 6e-29
7299437 [R] KOG0586 Serine/threonine protein kinase 127 6e-29
At4g14580 [T] KOG0583 Serine/threonine protein kinase 126 8e-29
At2g34650 [R] KOG0610 Putative serine/threonine protein kinase 126 8e-29
CE02074 [T] KOG0986 G protein-coupled receptor kinase 126 1e-28
At3g23000 [T] KOG0583 Serine/threonine protein kinase 126 1e-28
YPR111w [R] KOG0605 NDR and related serine/threonine kinases 125 1e-28
Hs4505831 [T] KOG0612 Rho-associated coiled-coil containing prot... 125 1e-28
At3g12690 [R] KOG0610 Putative serine/threonine protein kinase 125 1e-28
At3g06030 [T] KOG0198 MEKK and related serine/threonine protein ... 125 1e-28
At2g30360 [T] KOG0583 Serine/threonine protein kinase 125 2e-28
At2g25880 [D] KOG0580 Serine/threonine protein kinase 124 3e-28
YPL209c [D] KOG0580 Serine/threonine protein kinase 124 4e-28
CE17284 [T] KOG0583 Serine/threonine protein kinase 124 4e-28
Hs16357474_1 [T] KOG0612 Rho-associated coiled-coil containing p... 124 4e-28
At3g01090 [T] KOG0583 Serine/threonine protein kinase 124 5e-28
At2g25090 [T] KOG0583 Serine/threonine protein kinase 124 5e-28
CE11916 [T] KOG0612 Rho-associated coiled-coil containing protei... 123 6e-28
CE28218 [D] KOG0588 Serine/threonine protein kinase 123 8e-28
Hs9845489 [R] KOG0586 Serine/threonine protein kinase 122 1e-27
Hs9845487 [R] KOG0586 Serine/threonine protein kinase 122 1e-27
Hs22062450 [R] KOG0586 Serine/threonine protein kinase 122 1e-27
Hs14728804 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 122 1e-27
At5g39440 [T] KOG0583 Serine/threonine protein kinase 122 1e-27
At5g35410 [T] KOG0583 Serine/threonine protein kinase 122 1e-27
CE07156 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 122 2e-27
SPBC21.06c [T] KOG0198 MEKK and related serine/threonine protein... 121 2e-27
7293666 [D] KOG0575 Polo-like serine/threonine protein kinase 121 2e-27
7293496 [R] KOG0597 Serine-threonine protein kinase FUSED 121 2e-27
7299438 [R] KOG0586 Serine/threonine protein kinase 121 3e-27
At1g50230 [R] KOG0597 Serine-threonine protein kinase FUSED 120 4e-27
Hs8923922 [R] KOG0586 Serine/threonine protein kinase 120 5e-27
Hs20545245 [D] KOG0588 Serine/threonine protein kinase 120 5e-27
At5g25110 [T] KOG0583 Serine/threonine protein kinase 120 5e-27
SPCC297.03 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 120 7e-27
At3g29160 [T] KOG0583 Serine/threonine protein kinase 120 7e-27
At3g17510 [T] KOG0583 Serine/threonine protein kinase 120 7e-27
At1g53570 [T] KOG0198 MEKK and related serine/threonine protein ... 120 7e-27
At4g09570 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 119 9e-27
Hs7657214 [T] KOG0583 Serine/threonine protein kinase 119 1e-26
At2g26980 [T] KOG0583 Serine/threonine protein kinase 119 1e-26
YMR001c [D] KOG0575 Polo-like serine/threonine protein kinase 119 2e-26
YLR096w [T] KOG0583 Serine/threonine protein kinase 119 2e-26
Hs7662170 [R] KOG0611 Predicted serine/threonine protein kinase 118 2e-26
CE15235 [R] KOG0589 Serine/threonine protein kinase 118 2e-26
At4g18700 [T] KOG0583 Serine/threonine protein kinase 118 2e-26
Hs4505599 [T] KOG0578 p21-activated serine/threonine protein kinase 118 3e-26
At5g01810 [T] KOG0583 Serine/threonine protein kinase 117 3e-26
At1g30270 [T] KOG0583 Serine/threonine protein kinase 117 3e-26
Hs13899225 [R] KOG0586 Serine/threonine protein kinase 117 5e-26
CE05780 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 117 5e-26
At1g48260 [T] KOG0583 Serine/threonine protein kinase 117 5e-26
7304311 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 117 5e-26
7293512 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 117 5e-26
7290249 [R] KOG0586 Serine/threonine protein kinase 117 5e-26
CE26793_1 [R] KOG0611 Predicted serine/threonine protein kinase 117 5e-26
SPCC162.10 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 116 8e-26
Hs4505153 [T] KOG0198 MEKK and related serine/threonine protein ... 116 8e-26
CE25046 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 116 8e-26
7302570 [R] KOG0586 Serine/threonine protein kinase 116 8e-26
7302464 [R] KOG0586 Serine/threonine protein kinase 116 8e-26
Hs4557511 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 116 1e-25
HsM7657627 [D] KOG0575 Polo-like serine/threonine protein kinase 115 1e-25
Hs21361433 [D] KOG0575 Polo-like serine/threonine protein kinase 115 1e-25
7297611 [T] KOG0614 cGMP-dependent protein kinase 115 1e-25
Hs22042851 [T] KOG0986 G protein-coupled receptor kinase 115 2e-25
Hs14776113 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 115 2e-25
HsM4505103 [R] KOG0586 Serine/threonine protein kinase 115 2e-25
At1g63700 [T] KOG0198 MEKK and related serine/threonine protein ... 115 2e-25
At1g54960 [T] KOG0198 MEKK and related serine/threonine protein ... 115 2e-25
At1g35670 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 115 2e-25
At1g01140 [T] KOG0583 Serine/threonine protein kinase 115 2e-25
YDR122w [T] KOG0583 Serine/threonine protein kinase 114 3e-25
Hs13569922 [R] KOG0611 Predicted serine/threonine protein kinase 114 3e-25
At4g30960 [T] KOG0583 Serine/threonine protein kinase 114 3e-25
At1g09000 [T] KOG0198 MEKK and related serine/threonine protein ... 114 3e-25
SPACUNK12.02c [T] KOG0032 Ca2+/calmodulin-dependent protein kina... 114 4e-25
Hs4758016 [D] KOG0575 Polo-like serine/threonine protein kinase 114 4e-25
SPAC23C11.16 [D] KOG0575 Polo-like serine/threonine protein kinase 113 9e-25
Hs4502557 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 113 9e-25
Hs20547806 [R] KOG0589 Serine/threonine protein kinase 113 9e-25
At1g29230 [T] KOG0583 Serine/threonine protein kinase 113 9e-25
YOR351c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 112 1e-24
SPBC32C12.03c [T] KOG0583 Serine/threonine protein kinase 112 1e-24
At5g10930 [T] KOG0583 Serine/threonine protein kinase 112 1e-24
At1g18890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 112 1e-24
SPBC4F6.06 [T] KOG0583 Serine/threonine protein kinase 112 1e-24
Hs4505601 [T] KOG0578 p21-activated serine/threonine protein kinase 112 1e-24
Hs10334852 [T] KOG0612 Rho-associated coiled-coil containing pro... 112 1e-24
At5g45820 [T] KOG0583 Serine/threonine protein kinase 112 1e-24
At5g45810 [T] KOG0583 Serine/threonine protein kinase 112 1e-24
At3g13530 [T] KOG0198 MEKK and related serine/threonine protein ... 112 1e-24
CE28251 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 112 2e-24
At3g61960 [OUT] KOG0595 Serine/threonine-protein kinase involved... 112 2e-24
At3g15220 [T] KOG0201 Serine/threonine protein kinase 112 2e-24
7294217 [D] KOG0588 Serine/threonine protein kinase 112 2e-24
Hs4826684_1 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 111 3e-24
YPL153c [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 111 3e-24
YKL101w [D] KOG0588 Serine/threonine protein kinase 111 3e-24
YDR507c [D] KOG0588 Serine/threonine protein kinase 111 3e-24
Hs20479818 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 111 3e-24
ECU07g0360 [D] KOG0580 Serine/threonine protein kinase 111 3e-24
At5g23580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 111 3e-24
7292679 [G] KOG0599 Phosphorylase kinase gamma subunit 111 3e-24
SPCC18B5.11c [D] KOG0615 Serine/threonine protein kinase Chk2 an... 110 4e-24
Hs7662210 [OUT] KOG0595 Serine/threonine-protein kinase involved... 110 4e-24
Hs7661974 [T] KOG0583 Serine/threonine protein kinase 110 4e-24
Hs6005850 [D] KOG0615 Serine/threonine protein kinase Chk2 and r... 110 4e-24
CE00847 [T] KOG0583 Serine/threonine protein kinase 110 4e-24
7298926 [T] KOG0578 p21-activated serine/threonine protein kinase 110 4e-24
Hs21735556 [T] KOG0198 MEKK and related serine/threonine protein... 110 6e-24
At2g41860 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 110 6e-24
7298652 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 110 6e-24
SPAC890.03 [T] KOG0583 Serine/threonine protein kinase 110 7e-24
CE29300 [T] KOG0694 Serine/threonine protein kinase 110 7e-24
CE29299 [T] KOG0694 Serine/threonine protein kinase 110 7e-24
CE01146 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 110 7e-24
Hs4758128_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 110 7e-24
Hs16950621 [Z] KOG0613 Projectin/twitchin and related proteins 109 1e-23
Hs16950613 [Z] KOG0613 Projectin/twitchin and related proteins 109 1e-23
Hs16950611 [Z] KOG0613 Projectin/twitchin and related proteins 109 1e-23
Hs16950601 [Z] KOG0613 Projectin/twitchin and related proteins 109 1e-23
Hs14042947 [T] KOG0583 Serine/threonine protein kinase 109 1e-23
At5g01820 [T] KOG0583 Serine/threonine protein kinase 109 1e-23
At3g07980 [T] KOG0198 MEKK and related serine/threonine protein ... 109 1e-23
YCL024w [T] KOG0583 Serine/threonine protein kinase 109 1e-23
SPBC1D7.05c [T] KOG0198 MEKK and related serine/threonine protei... 109 1e-23
Hs7661994 [T] KOG0579 Ste20-like serine/threonine protein kinase 109 1e-23
Hs5730055 [D] KOG0575 Polo-like serine/threonine protein kinase 109 1e-23
Hs4507831 [OUT] KOG0595 Serine/threonine-protein kinase involved... 109 1e-23
CE20564 [T] KOG0578 p21-activated serine/threonine protein kinase 109 1e-23
CE05425 [T] KOG0578 p21-activated serine/threonine protein kinase 109 1e-23
SPCC74.03c [T] KOG0583 Serine/threonine protein kinase 108 2e-23
Hs7382496 [T] KOG0578 p21-activated serine/threonine protein kinase 108 2e-23
Hs22050308_2 [T] KOG0198 MEKK and related serine/threonine prote... 108 2e-23
SPAC644.06c [D] KOG0588 Serine/threonine protein kinase 108 2e-23
Hs21361643 [T] KOG4717 Serine/threonine protein kinase 108 2e-23
At3g20860 [R] KOG0589 Serine/threonine protein kinase 108 2e-23
7303211 [T] KOG4717 Serine/threonine protein kinase 108 2e-23
At1g49180_1 [OUT] KOG0595 Serine/threonine-protein kinase involv... 108 2e-23
Hs6031180 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and... 108 3e-23
Hs5803088 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and... 108 3e-23
CE16081 [T] KOG0583 Serine/threonine protein kinase 108 3e-23
7290150 [T] KOG0583 Serine/threonine protein kinase 108 3e-23
Hs4505373 [V] KOG1826 Ras GTPase activating protein RasGAP/neuro... 107 4e-23
Hs14770402 [R] KOG0586 Serine/threonine protein kinase 107 4e-23
CE28479 [T] KOG0583 Serine/threonine protein kinase 107 4e-23
At4g04740 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 107 4e-23
YOL016c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 107 5e-23
Hs5174701 [T] KOG0579 Ste20-like serine/threonine protein kinase 107 5e-23
At1g74740 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 107 5e-23
Hs4507277_1 [R] KOG0589 Serine/threonine protein kinase 107 5e-23
SPCC1450.11c [R] KOG0605 NDR and related serine/threonine kinases 107 6e-23
HsM5729922 [T] KOG0198 MEKK and related serine/threonine protein... 107 6e-23
Hs19424132 [D] KOG0591 NIMA (never in mitosis)-related G2-specif... 107 6e-23
Hs14670383 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 107 6e-23
CE23001 [R] KOG0589 Serine/threonine protein kinase 107 6e-23
At2g34180 [T] KOG0583 Serine/threonine protein kinase 107 6e-23
7294537 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 107 6e-23
At1g12580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 106 8e-23
CE09360 [Z] KOG0613 Projectin/twitchin and related proteins 106 1e-22
At1g53165 [T] KOG0201 Serine/threonine protein kinase 106 1e-22
CE27894_1 [R] KOG0589 Serine/threonine protein kinase 106 1e-22
YCR073c [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and r... 105 1e-22
At1g76040 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 105 1e-22
YFR014c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 105 2e-22
YDR477w [T] KOG0583 Serine/threonine protein kinase 105 2e-22
SPCC63.08c [OUT] KOG0595 Serine/threonine-protein kinase involve... 105 2e-22
At5g58950 [T] KOG0192 Tyrosine kinase specific for activated (GT... 105 2e-22
At1g12680 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 105 2e-22
7291778 [T] KOG0579 Ste20-like serine/threonine protein kinase 105 2e-22
YJL095w [T] KOG0198 MEKK and related serine/threonine protein ki... 105 2e-22
Hs21361133 [R] KOG0586 Serine/threonine protein kinase 105 2e-22
At4g04720 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 105 2e-22
At1g54510 [R] KOG0589 Serine/threonine protein kinase 105 2e-22
YOR233w [T] KOG0583 Serine/threonine protein kinase 104 3e-22
YGL180w [OUT] KOG0595 Serine/threonine-protein kinase involved i... 104 3e-22
YGL158w [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 104 3e-22
CE27297 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 104 3e-22
At3g45240 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase k... 104 4e-22
7297080 [T] KOG0583 Serine/threonine protein kinase 104 4e-22
Hs4505785 [G] KOG0599 Phosphorylase kinase gamma subunit 103 5e-22
Hs14916455 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 103 5e-22
At5g60550 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase k... 103 5e-22
At5g07070 [T] KOG0583 Serine/threonine protein kinase 103 5e-22
7296450 [D] KOG0575 Polo-like serine/threonine protein kinase 103 5e-22
SPBC725.06c [R] KOG0605 NDR and related serine/threonine kinases 103 7e-22
Hs5174547 [T] KOG4279 Serine/threonine protein kinase 103 7e-22
CE28674 [T] KOG0201 Serine/threonine protein kinase 103 7e-22
CE07510 [T] KOG0201 Serine/threonine protein kinase 103 7e-22
At3g10660 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 103 7e-22
7300413 [T] KOG0583 Serine/threonine protein kinase 103 7e-22
SPAC57A10.02 [D] KOG0588 Serine/threonine protein kinase 103 9e-22
CE03584 [T] KOG0607 MAP kinase-interacting kinase and related se... 103 9e-22
At2g37840 [OUT] KOG0595 Serine/threonine-protein kinase involved... 103 9e-22
Hs14141724 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase ... 102 1e-21
At5g28290 [R] KOG0589 Serine/threonine protein kinase 102 1e-21
7290841 [D] KOG0591 NIMA (never in mitosis)-related G2-specific ... 102 1e-21
SPAC1F3.02c [T] KOG0198 MEKK and related serine/threonine protei... 102 2e-21
Hs14993776 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 102 2e-21
At5g55090 [T] KOG0198 MEKK and related serine/threonine protein ... 102 2e-21
YPL141c [T] KOG0583 Serine/threonine protein kinase 102 2e-21
SPAC2C4.14c [T] KOG0201 Serine/threonine protein kinase 102 2e-21
HsM4505191 [T] KOG0607 MAP kinase-interacting kinase and related... 102 2e-21
At1g14000 [T] KOG0192 Tyrosine kinase specific for activated (GT... 102 2e-21
YLR362w [T] KOG0198 MEKK and related serine/threonine protein ki... 101 3e-21
YHL007c [T] KOG0578 p21-activated serine/threonine protein kinase 101 3e-21
SPAC14C4.03 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 101 3e-21
HsM4826916 [D] KOG0575 Polo-like serine/threonine protein kinase 101 3e-21
Hs20070158 [T] KOG0201 Serine/threonine protein kinase 101 3e-21
CE28061 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 101 3e-21
CE28060 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 101 3e-21
CE28059 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 101 3e-21
CE28058 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 101 3e-21
CE28057 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 101 3e-21
CE28056 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 101 3e-21
CE28055 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 101 3e-21
CE28054 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 101 3e-21
CE28053 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 101 3e-21
CE28051 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 101 3e-21
CE21879 [D] KOG0590 Checkpoint kinase and related serine/threoni... 101 3e-21
At4g26890 [T] KOG0198 MEKK and related serine/threonine protein ... 101 3e-21
At2g38910 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 101 3e-21
7304358 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 101 3e-21
7304283 [Z] KOG0613 Projectin/twitchin and related proteins 101 3e-21
7296128 [T] KOG0583 Serine/threonine protein kinase 101 3e-21
SPBC1604.14c [T] KOG0578 p21-activated serine/threonine protein ... 101 3e-21
Hs7706286 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase E... 101 3e-21
Hs17933758 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 101 3e-21
Hs5031975 [T] KOG0578 p21-activated serine/threonine protein kinase 100 4e-21
Hs21359873 [D] KOG0575 Polo-like serine/threonine protein kinase 100 4e-21
Hs19923407 [D] KOG0591 NIMA (never in mitosis)-related G2-specif... 100 4e-21
At4g23650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 100 4e-21
At2g35890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 100 4e-21
Hs19311016_1 [R] KOG0589 Serine/threonine protein kinase 100 4e-21
SPCC1259.13 [D] KOG0590 Checkpoint kinase and related serine/thr... 100 6e-21
Hs4758700 [T] KOG0604 MAP kinase-activated protein kinase 2 100 6e-21
Hs15011928 [R] KOG0594 Protein kinase PCTAIRE and related kinases 100 6e-21
Hs14777335 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 100 6e-21
At5g19360 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 100 6e-21
At5g04870 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 100 6e-21
At2g38490 [T] KOG0583 Serine/threonine protein kinase 100 6e-21
At5g66850 [T] KOG0198 MEKK and related serine/threonine protein ... 100 8e-21
At4g08500 [T] KOG0198 MEKK and related serine/threonine protein ... 100 8e-21
7300224 [T] KOG0201 Serine/threonine protein kinase 100 8e-21
Hs5453882 [G] KOG0599 Phosphorylase kinase gamma subunit 100 1e-20
Hs14249562 [TR] KOG0606 Microtubule-associated serine/threonine ... 100 1e-20
ECU01g0630 [D] KOG0575 Polo-like serine/threonine protein kinase 100 1e-20
CE27670 [T] KOG0578 p21-activated serine/threonine protein kinase 100 1e-20
CE27583 [T] KOG0604 MAP kinase-activated protein kinase 2 100 1e-20
CE17545 [T] KOG0604 MAP kinase-activated protein kinase 2 100 1e-20
At5g12180 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 100 1e-20
7300437 [TR] KOG0606 Microtubule-associated serine/threonine kin... 100 1e-20
Hs14150045 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 99 1e-20
CE12518 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 99 1e-20
At5g58380 [T] KOG0583 Serine/threonine protein kinase 99 1e-20
At5g57630 [T] KOG0583 Serine/threonine protein kinase 99 1e-20
At4g40010 [T] KOG0583 Serine/threonine protein kinase 99 1e-20
At3g19100 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 99 1e-20
At3g04810 [R] KOG0589 Serine/threonine protein kinase 99 1e-20
7301213 [R] KOG0589 Serine/threonine protein kinase 99 1e-20
7299507 [T] KOG0607 MAP kinase-interacting kinase and related se... 99 1e-20
SPAC9G1.02 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 an... 99 2e-20
HsM5454174 [T] KOG0201 Serine/threonine protein kinase 99 2e-20
Hs9910476 [T] KOG0578 p21-activated serine/threonine protein kinase 99 2e-20
Hs5454096 [T] KOG0574 STE20-like serine/threonine kinase MST 99 2e-20
Hs21361358 [T] KOG0201 Serine/threonine protein kinase 99 2e-20
Hs20545357 [T] KOG0583 Serine/threonine protein kinase 99 2e-20
Hs15011880 [T] KOG0201 Serine/threonine protein kinase 99 2e-20
Hs14771959 [T] KOG0578 p21-activated serine/threonine protein ki... 99 2e-20
CE28643 [T] KOG0583 Serine/threonine protein kinase 99 2e-20
CE07458 [T] KOG0583 Serine/threonine protein kinase 99 2e-20
At3g46930 [T] KOG0192 Tyrosine kinase specific for activated (GT... 99 2e-20
At1g08650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 99 2e-20
Hs5453966 [T] KOG0583 Serine/threonine protein kinase 99 2e-20
Hs22043888 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 99 2e-20
7299160 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 99 2e-20
7289880 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 99 2e-20
Hs8923539 [R] KOG0597 Serine-threonine protein kinase FUSED 98 3e-20
Hs15451902 [T] KOG0576 Mitogen-activated protein kinase kinase k... 98 3e-20
CE24516 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 98 3e-20
At5g19450 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 98 3e-20
YFL033c [R] KOG0605 NDR and related serine/threonine kinases 98 4e-20
CE29020 [T] KOG0660 Mitogen-activated protein kinase 98 4e-20
CE07905 [T] KOG0579 Ste20-like serine/threonine protein kinase 98 4e-20
At4g21940 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 98 4e-20
At3g04530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 98 4e-20
YPL031c [R] KOG0594 Protein kinase PCTAIRE and related kinases 97 5e-20
HsM8923212 [T] KOG4717 Serine/threonine protein kinase 97 5e-20
Hs4507281 [R] KOG0593 Predicted protein kinase KKIAMRE 97 5e-20
CE21615 [T] KOG0578 p21-activated serine/threonine protein kinase 97 5e-20
CE06635 [Z] KOG0613 Projectin/twitchin and related proteins 97 5e-20
CE06634 [Z] KOG0613 Projectin/twitchin and related proteins 97 5e-20
At3g57530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 97 5e-20
At1g61950 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 97 5e-20
CE18058_1 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 97 5e-20
CE18454 [T] KOG4717 Serine/threonine protein kinase 97 6e-20
At2g31500 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 97 6e-20
At2g26700_2 [R] KOG0610 Putative serine/threonine protein kinase 97 6e-20
YDL028c [D] KOG0596 Dual specificity; serine/threonine and tyros... 97 8e-20
Hs5453964 [T] KOG0583 Serine/threonine protein kinase 97 8e-20
ECU01g1320 [T] KOG0612 Rho-associated coiled-coil containing pro... 97 8e-20
CE29466 [T] KOG0665 Jun-N-terminal kinase (JNK) 97 8e-20
CE24971 [T] KOG0660 Mitogen-activated protein kinase 97 8e-20
CE03232 [D] KOG0591 NIMA (never in mitosis)-related G2-specific ... 97 8e-20
CE01583 [T] KOG0660 Mitogen-activated protein kinase 97 8e-20
At4g29810 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 97 8e-20
At2g32510 [T] KOG0198 MEKK and related serine/threonine protein ... 97 8e-20
7290629 [T] KOG0604 MAP kinase-activated protein kinase 2 97 8e-20
YGL179c [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 96 1e-19
Hs5454094 [T] KOG0574 STE20-like serine/threonine kinase MST 96 1e-19
Hs16178962 [T] KOG0574 STE20-like serine/threonine kinase MST 96 1e-19
At3g27580 [R] KOG0610 Putative serine/threonine protein kinase 96 1e-19
At1g49580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 96 1e-19
SPAC23H4.02 [T] KOG0583 Serine/threonine protein kinase 96 1e-19
Hs9994197 [T] KOG0607 MAP kinase-interacting kinase and related ... 96 1e-19
Hs5453860 [R] KOG0594 Protein kinase PCTAIRE and related kinases 96 1e-19
CE17305 [T] KOG0665 Jun-N-terminal kinase (JNK) 96 1e-19
Hs22057171 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 96 2e-19
YDL101c [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 95 2e-19
SPCC16C4.11 [R] KOG0594 Protein kinase PCTAIRE and related kinases 95 3e-19
Hs4557439 [R] KOG0594 Protein kinase PCTAIRE and related kinases 95 3e-19
Hs22043324 [T] KOG0603 Ribosomal protein S6 kinase 95 3e-19
Hs16507245 [T] KOG0583 Serine/threonine protein kinase 95 3e-19
CE07599 [T] KOG0576 Mitogen-activated protein kinase kinase kina... 95 3e-19
At3g20410 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 94 4e-19
>YBR028c [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 525
Score = 516 bits (1329), Expect = e-146
Identities = 284/532 (53%), Positives = 351/532 (65%), Gaps = 34/532 (6%)
Query: 44 LSTMNLPLHKNQFRMDLSALPPNTYEEEALISDTEEQAEMMSGFLVPPDSGESKQSQTKE 103
L ++L KN ++D S+ N E S T E E ++ V ++
Sbjct: 9 LHRVSLDDKKNDIKVDYSSAIYNDINHEQGSSITYE--ESINHLSVHSNAIPLNGMSPAH 66
Query: 104 PARRRSSLYNKFVVNPAQHTIRLSLNAQGDSDKETRDVLSVSSVEETRQLRASSFSKTGA 163
RRRSS Y+KF + +T R S+ D+ + + LS++ + + +S+ +
Sbjct: 67 RMRRRSSAYSKFPILTPPNTRRFSITGS-DAMRTNTNRLSITP----QDIISSNIGENEL 121
Query: 164 PRVLDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILIS--------EDSIEK 215
R L DF P+R LG+GAYG YAMKQL+KAEILIS ED +
Sbjct: 122 SRNLHDFKPVRVLGQGAYGKVLLVKDVNTSKLYAMKQLRKAEILISQTATDSKREDEDKN 181
Query: 216 DANTT-----VEKRIERTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFY 270
D N + KR+ERTFAER+ILS++EHPNIVKLFYSFHDN KLYL+LQYIPGGELFY
Sbjct: 182 DGNNNDNDDGLSKRLERTFAERSILSEIEHPNIVKLFYSFHDNSKLYLLLQYIPGGELFY 241
Query: 271 HLKEQGTLDEGTVAFYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKK 330
HLKE GTLDE TV+FYAAE+SCAL+FLH+KG+VYRDLKPENCLLN+RGHLVLTDFGLSKK
Sbjct: 242 HLKEHGTLDETTVSFYAAEISCALRFLHTKGVVYRDLKPENCLLNQRGHLVLTDFGLSKK 301
Query: 331 SVFDDAATPEEGENVNQLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPP 390
S D A E+ ENVN LYSIIGTPEYCAPEIL G+ Y+QNCDWYSLGCL+YDML+GKPP
Sbjct: 302 SANDSAVDEEDPENVNALYSIIGTPEYCAPEILLGKAYSQNCDWYSLGCLLYDMLVGKPP 361
Query: 391 FTGVNHKIILNKIKQEKTGARIPSYLSDGFKDYLGALLRKDPTKRWDVDKYWAQDG---- 446
+TG NHK+I+NKI+Q K G +IP YLS+G KD L ALL+K+ KRW+VDKYWA+ G
Sbjct: 362 YTGSNHKVIINKIQQNKQGPKIPFYLSEGMKDILNALLKKETAKRWNVDKYWAKTGANNK 421
Query: 447 PXXXXXXXXXXXXXN-YIGHFIFRKIIWKQLLSGDLQKISVGPILPIITDWELAENFDTE 505
P + + HFIFRKI WK L SG LQK ++GPI+P+ITD ELAENFDTE
Sbjct: 422 PTKSKKKKSGAARTSLFTEHFIFRKIDWKLLESGQLQKTTLGPIVPVITDLELAENFDTE 481
Query: 506 FTEKRLDTSIYDN-GIEINNPRATKESAFAGSTDYFKGFSYVASRSYLERHF 556
FT + + D+ I IN + + S D FKGFSY AS SYLE++F
Sbjct: 482 FTSMSYEETYTDSKPININ--------SVSKSPDMFKGFSYKASGSYLEKYF 525
>SPCC4G3.08 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 436
Score = 265 bits (676), Expect = 2e-70
Identities = 160/388 (41%), Positives = 212/388 (54%), Gaps = 50/388 (12%)
Query: 169 DFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIERT 228
DF P+ LG G+YG +A KQLKKA I++ +E+ N
Sbjct: 90 DFQPLTVLGRGSYGKVLLVKQKNTGRLFAQKQLKKASIVLRAKGLEQTKN---------- 139
Query: 229 FAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAA 288
ER IL ++ HP I +L+Y+F D+ +LYL+LQY PGGELF HL EQ L E VAFY A
Sbjct: 140 --ERQILEEVRHPFICRLYYAFQDHDRLYLILQYAPGGELFSHLAEQRMLPEDVVAFYTA 197
Query: 289 ELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVNQL 348
EL+ AL LH GIVYRDLKPENCLL+ GH++LTDFGLSK + EN
Sbjct: 198 ELTLALIHLHKLGIVYRDLKPENCLLDAEGHILLTDFGLSKVA-----------ENGADC 246
Query: 349 YSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQEKT 408
S +GT EYCAPEIL +PY DW+S+G L++D+L G PPFT NHK I+ KI + K
Sbjct: 247 RSFVGTEEYCAPEILLEQPYDHAVDWWSMGILIFDLLTGSPPFTANNHKRIMEKITRAK- 305
Query: 409 GARIPSYLSDGFKDYLGALLRKDPTKRWDVDKYWAQDGPXXXXXXXXXXXXXNYIGHFIF 468
IP Y++ +D + L+K+P +R DGP H I+
Sbjct: 306 -PNIPFYVTSDARDIINKFLKKNPKQR------LGADGPEKGYDAIKK--------HRIY 350
Query: 469 RKIIWKQLLSGDLQKISVGPILPIITDWELAENFDTEFTEKRLDTSIYDNGIEINNPRAT 528
R+I W +L +++ PI+P IT+ E AENF EFT+ L T+ + N +
Sbjct: 351 RRIDWNKL----EKRMLPPPIVPCITNPEAAENFSVEFTKLPLSTTPILHEEFGNLTIGS 406
Query: 529 KESAFAGSTDYFKGFSYVASRSYLERHF 556
SA F+GF+YVAS ++L F
Sbjct: 407 HSSA-------FQGFTYVASPNFLNCEF 427
>Hs4506737 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 525
Score = 214 bits (544), Expect = 4e-55
Identities = 142/381 (37%), Positives = 192/381 (50%), Gaps = 59/381 (15%)
Query: 170 FVPIRCLGEGAYGXXXXXXXXXXXXX---YAMKQLKKAEILISEDSIEKDANTTVEKRIE 226
F +R LG+G YG +AMK LKKA I+ ++A T
Sbjct: 91 FELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIV-------RNAKDTAH---- 139
Query: 227 RTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFY 286
T AER IL +++HP IV L Y+F KLYL+L+Y+ GGELF L+ +G E T FY
Sbjct: 140 -TKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTACFY 198
Query: 287 AAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVN 346
AE+S AL LH KGI+YRDLKPEN +LN +GH+ LTDFGL K+S+ D T
Sbjct: 199 LAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDGTVT-------- 250
Query: 347 QLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQE 406
++ GT EY APEIL + + DW+SLG L+YDML G PPFTG N K ++KI
Sbjct: 251 --HTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKIL-- 306
Query: 407 KTGARIPSYLSDGFKDYLGALLRKDPTKRWDVDKYWAQDGPXXXXXXXXXXXXXNYIGHF 466
K +P YL+ +D L LL+++ R GP H
Sbjct: 307 KCKLNLPPYLTQEARDLLKKLLKRNAASRLGA-------GPGDAGEVQ---------AHP 350
Query: 467 IFRKIIWKQLLSGDLQKISVGPILPIITDWELAENFDTEFTEKRLDTSIYDNGIEINNPR 526
FR I W++LL+ ++ P P++ E FD++FT + ++ +
Sbjct: 351 FFRHINWEELLARKVEP----PFKPLLQSEEDVSQFDSKFTRQ--------TPVDSPDDS 398
Query: 527 ATKESAFAGSTDYFKGFSYVA 547
ESA F GF+YVA
Sbjct: 399 TLSESA----NQVFLGFTYVA 415
>YMR104c [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 677
Score = 208 bits (529), Expect = 2e-53
Identities = 131/358 (36%), Positives = 184/358 (50%), Gaps = 55/358 (15%)
Query: 164 PRVLDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEK 223
P +DDF ++ +G+G++G YA+K L+KA I+ +
Sbjct: 338 PLSIDDFDLLKVIGKGSFGKVMQVRKKDTQKIYALKALRKAYIVSKCE------------ 385
Query: 224 RIERTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTV 283
+ T AERT+L++++ P IV L +SF KLYLVL +I GGELFYHL+ +G
Sbjct: 386 -VTHTLAERTVLARVDCPFIVPLKFSFQSPEKLYLVLAFINGGELFYHLQHEGRFSLARS 444
Query: 284 AFYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGE 343
FY AEL CAL LH ++YRDLKPEN LL+ +GH+ L DFGL K ++ D+ T
Sbjct: 445 RFYIAELLCALDSLHKLDVIYRDLKPENILLDYQGHIALCDFGLCKLNMKDNDKTD---- 500
Query: 344 NVNQLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKI 403
+ GTPEY APEIL G+ YT+ DW++LG L+Y+M+ G PP+ N ++ KI
Sbjct: 501 ------TFCGTPEYLAPEILLGQGYTKTVDWWTLGILLYEMMTGLPPYYDENVPVMYKKI 554
Query: 404 KQEKTGARIPSYLSDGF----KDYLGALLRKDPTKRWDVDKYWAQDGPXXXXXXXXXXXX 459
Q+ P DGF KD L LL +DP++R V+
Sbjct: 555 LQQ------PLLFPDGFDPAAKDLLIGLLSRDPSRRLGVN------------------GT 590
Query: 460 XNYIGHFIFRKIIWKQLLSGDLQKISVGPILPIITDWELAENFDTEFTEKRLDTSIYD 517
H F+ I WK+L L K + P PI+ NFD EFT+++ S+ D
Sbjct: 591 DEIRNHPFFKDISWKKL----LLKGYIPPYKPIVKSEIDTANFDQEFTKEKPIDSVVD 644
>Hs4506739 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 495
Score = 207 bits (528), Expect = 3e-53
Identities = 139/381 (36%), Positives = 193/381 (50%), Gaps = 59/381 (15%)
Query: 170 FVPIRCLGEGAYGXXXXXXXXXXXXX---YAMKQLKKAEILISEDSIEKDANTTVEKRIE 226
F +R LG+G YG YAMK L+KA+I+ ++A T R
Sbjct: 80 FELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIV-------RNAKDTAHTR-- 130
Query: 227 RTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFY 286
AER IL ++HP IV+L Y+F KLYL+L+ + GGELF HL+ +G E T FY
Sbjct: 131 ---AERNILESVKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFY 187
Query: 287 AAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVN 346
AE++ AL LHS+GI+YRDLKPEN +L+ +GH+ LTDFGL K+S+ + A T
Sbjct: 188 LAEITLALGHLHSQGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAVT-------- 239
Query: 347 QLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQE 406
++ GT EY APEIL + + DW+SLG L+YDML G PPFT N K ++KI +
Sbjct: 240 --HTFCGTIEYMAPEILVRSGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRG 297
Query: 407 KTGARIPSYLSDGFKDYLGALLRKDPTKRWDVDKYWAQDGPXXXXXXXXXXXXXNYIGHF 466
K +P YL+ +D + L+++P++R GP H
Sbjct: 298 KLA--LPPYLTPDARDLVKKFLKRNPSQR-------IGGGPGDAADVQR---------HP 339
Query: 467 IFRKIIWKQLLSGDLQKISVGPILPIITDWELAENFDTEFTEKRLDTSIYDNGIEINNPR 526
FR + W LL+ + P P + E FDT FT + ++ +
Sbjct: 340 FFRHMNWDDLLAWRVDP----PFRPCLQSEEDVSQFDTRFTRQ--------TPVDSPDDT 387
Query: 527 ATKESAFAGSTDYFKGFSYVA 547
A ESA F GF+YVA
Sbjct: 388 ALSESA----NQAFLGFTYVA 404
>YKL126w [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 680
Score = 205 bits (521), Expect = 2e-52
Identities = 129/358 (36%), Positives = 182/358 (50%), Gaps = 55/358 (15%)
Query: 164 PRVLDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEK 223
P +DDF ++ +G+G++G YA+K ++K+ I+ +
Sbjct: 341 PLSIDDFDLLKVIGKGSFGKVMQVRKKDTQKVYALKAIRKSYIVSKSE------------ 388
Query: 224 RIERTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTV 283
+ T AERT+L++++ P IV L +SF KLY VL +I GGELFYHL+++G D
Sbjct: 389 -VTHTLAERTVLARVDCPFIVPLKFSFQSPEKLYFVLAFINGGELFYHLQKEGRFDLSRA 447
Query: 284 AFYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGE 343
FY AEL CAL LH +VYRDLKPEN LL+ +GH+ L DFGL K ++ DD T
Sbjct: 448 RFYTAELLCALDNLHKLDVVYRDLKPENILLDYQGHIALCDFGLCKLNMKDDDKTD---- 503
Query: 344 NVNQLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKI 403
+ GTPEY APE+L G YT+ DW++LG L+Y+ML G PP+ + + KI
Sbjct: 504 ------TFCGTPEYLAPELLLGLGYTKAVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKI 557
Query: 404 KQEKTGARIPSYLSDGF----KDYLGALLRKDPTKRWDVDKYWAQDGPXXXXXXXXXXXX 459
QE P DGF KD L LL +DPT+R +
Sbjct: 558 LQE------PLVFPDGFDRDAKDLLIGLLSRDPTRRLGYN------------------GA 593
Query: 460 XNYIGHFIFRKIIWKQLLSGDLQKISVGPILPIITDWELAENFDTEFTEKRLDTSIYD 517
H F ++ WK+L L K + P P +++ NFD EFT ++ S+ D
Sbjct: 594 DEIRNHPFFSQLSWKRL----LMKGYIPPYKPAVSNSMDTSNFDEEFTREKPIDSVVD 647
>7295426 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 490
Score = 199 bits (507), Expect = 7e-51
Identities = 135/390 (34%), Positives = 192/390 (48%), Gaps = 59/390 (15%)
Query: 169 DFVPIRCLGEGAYGXXXXXXXXXXXXX---YAMKQLKKAEILISEDSIEKDANTTVEKRI 225
DF + LG+G YG +AMK LKKA I+ T +K
Sbjct: 76 DFELKKVLGKGGYGKVFQVRKTAGRDANKYFAMKVLKKASIV------------TNQKDT 123
Query: 226 ERTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAF 285
T AER IL ++HP IV+L Y+F + KLYL+L+Y+ GGELF HL+ +G E T F
Sbjct: 124 AHTRAERNILEAVKHPFIVELVYAFQTDGKLYLILEYLSGGELFMHLEREGIFLEDTTCF 183
Query: 286 YAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENV 345
Y +E+ AL LH GI+YRDLKPEN LL+ +GH+ LTDFGL K+ + + T
Sbjct: 184 YLSEIILALGHLHKLGIIYRDLKPENILLDAQGHVKLTDFGLCKEHIQEGIVT------- 236
Query: 346 NQLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQ 405
++ GT EY APEIL + + DW+SLG L++DML G PPFT N K + I +
Sbjct: 237 ---HTFCGTIEYMAPEILTRSGHGKAVDWWSLGALMFDMLTGVPPFTAENRKKTIETILK 293
Query: 406 EKTGARIPSYLSDGFKDYLGALLRKDPTKRWDVDKYWAQDGPXXXXXXXXXXXXXNYIGH 465
K +P+YL+ +D + L+++ +R GP H
Sbjct: 294 AK--LNLPAYLTPEARDLVRRLMKRQEPQR-------LGSGPEDAAAVQI---------H 335
Query: 466 FIFRKIIWKQLLSGDLQKISVGPILPIITDWELAENFDTEFTEKRLDTSIYDNGIEINNP 525
F+ + W +L+ L+ PI P++ + FDT FT + I +++P
Sbjct: 336 PFFKHVNWDDVLARRLEP----PIKPLLRSEDDVSQFDTRFTRQ----------IPVDSP 381
Query: 526 RATKESAFAGSTDYFKGFSYVASRSYLERH 555
T S A F+GF+YVA + H
Sbjct: 382 DDTTLSESANL--IFQGFTYVAPSILEDMH 409
>SPCC24B10.07 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 569
Score = 196 bits (498), Expect = 8e-50
Identities = 123/356 (34%), Positives = 177/356 (49%), Gaps = 48/356 (13%)
Query: 164 PRVLDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEK 223
P +D F ++ +G+G++G YA+K +KKA I+ +
Sbjct: 224 PLTIDAFELLKVVGKGSFGKVMQVRKRDTSRIYALKTMKKAHIVSRSE------------ 271
Query: 224 RIERTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTV 283
++ T AERT+L+Q+ +P IV L +SF KLYLVL ++ GGELF+HL+ +G D
Sbjct: 272 -VDHTLAERTVLAQVNNPFIVPLKFSFQSPGKLYLVLAFVNGGELFHHLQREGCFDTYRA 330
Query: 284 AFYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGE 343
FY AEL AL+ LH ++YRDLKPEN LL+ GH+ L DFGL K ++
Sbjct: 331 KFYIAELLVALECLHEFNVIYRDLKPENILLDYTGHIALCDFGLCKLNM----------A 380
Query: 344 NVNQLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKI 403
++ + GTPEY APE+L G YT+ DW++LG L+Y+M+ G PPF N + KI
Sbjct: 381 KTDRTNTFCGTPEYLAPELLLGHGYTKVVDWWTLGVLLYEMITGLPPFYDENINEMYRKI 440
Query: 404 KQEKTGARIPSYLSDGFKDYLGALLRKDPTKRWDVDKYWAQDGPXXXXXXXXXXXXXNYI 463
Q+ R P + + KD L LL + P KR
Sbjct: 441 LQDP--LRFPDNIDEKAKDLLSGLLTRAPEKR------------------LGSGGAQEIK 480
Query: 464 GHFIFRKIIWKQLLSGDLQKISVGPILPIITDWELAENFDTEFT-EKRLDTSIYDN 518
H F I WK+L + +Q P P + NFD+EFT E +D+ + D+
Sbjct: 481 NHPFFDDIDWKKLCAKKIQP----PFKPSVESAIDTSNFDSEFTSEIPMDSVVADS 532
>Hs5032091 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 431
Score = 193 bits (490), Expect = 7e-49
Identities = 143/438 (32%), Positives = 211/438 (47%), Gaps = 72/438 (16%)
Query: 125 RLSLNAQGDSDKETRDVLSVSSVEETRQLRASSFSKTGAPRVLD------------DFVP 172
+++ N+ E + +L +S +E + A+ + ++ DF
Sbjct: 41 KIANNSYACKHPEVQSILKISQPQEPELMNANPSPPPSPSQQINLGPSSNPHAKPSDFHF 100
Query: 173 IRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIERTFAER 232
++ +G+G++G YA+K L+K IL ++ EK I +ER
Sbjct: 101 LKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKE----------EKHI---MSER 147
Query: 233 TIL-SQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAAELS 291
+L ++HP +V L +SF KLY VL YI GGELFYHL+ + E FYAAE++
Sbjct: 148 NVLLKNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIA 207
Query: 292 CALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVNQLYSI 351
AL +LHS IVYRDLKPEN LL+ +GH+VLTDFGL K+++ ++ T +
Sbjct: 208 SALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTS----------TF 257
Query: 352 IGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPF----TGVNHKIILNKIKQEK 407
GTPEY APE+L +PY + DW+ LG ++Y+ML G PPF T + ILNK Q K
Sbjct: 258 CGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLK 317
Query: 408 TGARIPSYLSDGFKDYLGALLRKDPTKRWDVDKYWAQDGPXXXXXXXXXXXXXNYIGHFI 467
+++ + L LL+KD TKR A+D H
Sbjct: 318 PN------ITNSARHLLEGLLQKDRTKR-----LGAKD------------DFMEIKSHVF 354
Query: 468 FRKIIWKQLLSGDLQKISVGPILPIITDWELAENFDTEFTEKRLDTSIYDNGIEINNPRA 527
F I W L++ K P P ++ +FD EFTE+ + SI + + +
Sbjct: 355 FSLINWDDLIN----KKITPPFNPNVSGPNELRHFDPEFTEEPVPNSIGKSPDSVLVTAS 410
Query: 528 TKESAFAGSTDYFKGFSY 545
KE+A A F GFSY
Sbjct: 411 VKEAAEA-----FLGFSY 423
>At3g08720 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 471
Score = 192 bits (488), Expect = 1e-48
Identities = 142/447 (31%), Positives = 215/447 (47%), Gaps = 73/447 (16%)
Query: 113 NKFVVNPAQHTIRLSLNAQGDSDKETRDVLSVSSVEETRQLRASSFSKTGAPRVLDDFVP 172
NK + + ++ L +G+S KE + + + S + ++DF
Sbjct: 88 NKLTLRETEDSVDLVECVEGESIKENDEFSGNDDTDSEK-----SPEEVSGVVGIEDFEV 142
Query: 173 IRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIERTFAER 232
++ +G+GA+G YAMK ++K +I +EK+ E AER
Sbjct: 143 LKVVGQGAFGKVYQVRKKDTSEIYAMKVMRKDKI------VEKN-------HAEYMKAER 189
Query: 233 TILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAAELSC 292
IL++++HP IV+L YSF ++LYLVL +I GG LF+ L QG E Y AE+
Sbjct: 190 DILTKIDHPFIVQLKYSFQTKYRLYLVLDFINGGHLFFQLYHQGLFREDLARVYTAEIVS 249
Query: 293 ALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVNQLYSII 352
A+ LH KGI++RDLKPEN L++ GH++LTDFGL+K E E + S+
Sbjct: 250 AVSHLHEKGIMHRDLKPENILMDVDGHVMLTDFGLAK-----------EFEENTRSNSMC 298
Query: 353 GTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTG----VNHKIILNKIKQEKT 408
GT EY APEI+ G+ + + DW+S+G L+Y+ML GKPPF G + KI+ +KIK
Sbjct: 299 GTTEYMAPEIVRGKGHDKAADWWSVGILLYEMLTGKPPFLGSKGKIQQKIVKDKIK---- 354
Query: 409 GARIPSYLSDGFKDYLGALLRKDPTKRWDVDKYWAQDGPXXXXXXXXXXXXXNYIGHFIF 468
+P +LS+ L LL+K+P +R GP H F
Sbjct: 355 ---LPQFLSNEAHALLKGLLQKEPERR-------LGSGPSGAEEIKK---------HKWF 395
Query: 469 RKIIWKQLLSGDLQKISVGPILPIITDWELAENFDTEFTEKRLDTSIYDNGIEINNPRAT 528
+ I WK+L + ++Q P ++ + NFD +T D S+ D+ N A
Sbjct: 396 KAINWKKLEAREVQP----SFKPAVSGRQCIANFDKCWT----DMSVLDSPASSPNSDA- 446
Query: 529 KESAFAGSTDYFKGFSYV-ASRSYLER 554
+ F F+YV S+L R
Sbjct: 447 -------KANPFTNFTYVRPPHSFLHR 466
>At3g08730 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 465
Score = 189 bits (481), Expect = 7e-48
Identities = 119/326 (36%), Positives = 174/326 (52%), Gaps = 36/326 (11%)
Query: 114 KFVVNPAQHTIRLSLNAQGDSDKETRDVLSVSSVEETRQLRASSFSKTGAPRVLDDFVPI 173
K + + +I L +G+S KE D + + L +G + DDF +
Sbjct: 79 KLTLLETEDSIDLVECLEGESLKENDDFSGNDDSDNEKALEGDLVKVSGVVGI-DDFEVM 137
Query: 174 RCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIERTFAERT 233
+ +G+GA+G YAMK ++K I+ EK+ E AER
Sbjct: 138 KVVGKGAFGKVYQVRKKETSEIYAMKVMRKDHIM------EKN-------HAEYMKAERD 184
Query: 234 ILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAAELSCA 293
IL++++HP IV+L YSF ++LYLVL +I GG LF+ L QG E Y AE+ A
Sbjct: 185 ILTKIDHPFIVQLKYSFQTKYRLYLVLDFINGGHLFFQLYHQGLFREDLARVYTAEIVSA 244
Query: 294 LKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVNQLYSIIG 353
+ LH KGI++RDLKPEN L++ GH++LTDFGL+K E E + S+ G
Sbjct: 245 VSHLHEKGIMHRDLKPENILMDTDGHVMLTDFGLAK-----------EFEENTRSNSMCG 293
Query: 354 TPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTG----VNHKIILNKIKQEKTG 409
T EY APEI+ G+ + + DW+S+G L+Y+ML GKPPF G + KI+ +KIK
Sbjct: 294 TTEYMAPEIVRGKGHDKAADWWSVGILLYEMLTGKPPFLGSKGKIQQKIVKDKIK----- 348
Query: 410 ARIPSYLSDGFKDYLGALLRKDPTKR 435
+P +LS+ L LL+K+P +R
Sbjct: 349 --LPQFLSNEAHAILKGLLQKEPERR 372
>Hs20149547 [T] KOG0603 Ribosomal protein S6 kinase
Length = 735
Score = 186 bits (473), Expect = 6e-47
Identities = 128/382 (33%), Positives = 189/382 (48%), Gaps = 62/382 (16%)
Query: 170 FVPIRCLGEGAYGXXXXXXXXX---XXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIE 226
F ++ LG+G++G YAMK LKKA + + + R+
Sbjct: 62 FELLKVLGQGSFGKVFLVRKVTRPDSGHLYAMKVLKKATLKVRD-------------RV- 107
Query: 227 RTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFY 286
RT ER IL+ + HP +VKL Y+F KLYL+L ++ GG+LF L ++ E V FY
Sbjct: 108 RTKMERDILADVNHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFY 167
Query: 287 AAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVN 346
AEL+ L LHS GI+YRDLKPEN LL+E GH+ LTDFGLSK+++ ++
Sbjct: 168 LAELALGLDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKEAI----------DHEK 217
Query: 347 QLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQE 406
+ YS GT EY APE++ + ++ + DW+S G L+++ML G PF G + K + I +
Sbjct: 218 KAYSFCGTVEYMAPEVVNRQGHSHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKA 277
Query: 407 KTGARIPSYLSDGFKDYLGALLRKDPTKRWDVDKYWAQDGPXXXXXXXXXXXXXNYIGHF 466
K G +P +LS + L AL +++P R GP H
Sbjct: 278 KLG--MPQFLSTEAQSLLRALFKRNPANR-------LGSGPDGAEEIKR---------HV 319
Query: 467 IFRKIIWKQLLSGDLQKISVGPILPIITDWELAENFDTEFTEKRLDTSIYDNGIEINNPR 526
+ I W +L +++ P P + + FDTEFT + T GI +
Sbjct: 320 FYSTIDWNKLYRREIKP----PFKPAVAQPDDTFYFDTEFTSR---TPKDSPGIPPS--- 369
Query: 527 ATKESAFAGSTDYFKGFSYVAS 548
AG+ F+GFS+VA+
Sbjct: 370 -------AGAHQLFRGFSFVAT 384
Score = 97.1 bits (240), Expect = 6e-20
Identities = 79/277 (28%), Positives = 127/277 (45%), Gaps = 38/277 (13%)
Query: 168 DDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIER 227
D +V +G G+Y YA+K + K++ +D + +E
Sbjct: 416 DGYVVKETIGVGSYSECKRCVHKATNMEYAVKVIDKSK---------RDPSEEIE----- 461
Query: 228 TFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYA 287
+L +HPNI+ L + D +YLV + + GGEL + Q E +F
Sbjct: 462 -----ILLRYGQHPNIITLKDVYDDGKHVYLVTELMRGGELLDKILRQKFFSEREASFVL 516
Query: 288 AELSCALKFLHSKGIVYRDLKPENCL-LNERGH---LVLTDFGLSKKSVFDDAATPEEGE 343
+ +++LHS+G+V+RDLKP N L ++E G+ L + DFG +K+ E G
Sbjct: 517 HTIGKTVEYLHSQGVVHRDLKPSNILYVDESGNPECLRICDFGFAKQ------LRAENGL 570
Query: 344 NVNQLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFT---GVNHKIIL 400
+ Y T + APE+L + Y + CD +SLG L+Y ML G PF + IL
Sbjct: 571 LMTPCY----TANFVAPEVLKRQGYDEGCDIWSLGILLYTMLAGYTPFANGPSDTPEEIL 626
Query: 401 NKIKQEKTGARIPSY--LSDGFKDYLGALLRKDPTKR 435
+I K ++ +S+ KD + +L DP +R
Sbjct: 627 TRIGSGKFTLSGGNWNTVSETAKDLVSKMLHVDPHQR 663
>CE14798 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 422
Score = 186 bits (471), Expect = 1e-46
Identities = 114/348 (32%), Positives = 177/348 (50%), Gaps = 47/348 (13%)
Query: 168 DDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIER 227
+DF + +G+G++G YAMK ++S++ I K + ++
Sbjct: 92 NDFDYLTTIGKGSFGRVYQVRHKETKKIYAMK-------ILSKEHIRK------KNEVKH 138
Query: 228 TFAERTIL-SQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFY 286
AER +L + +HP +V L +SF + KLY VL ++ GGELF HL+ + E FY
Sbjct: 139 VMAERNVLINNFKHPFLVSLHFSFQNKEKLYFVLDHLNGGELFSHLQREKHFSESRSRFY 198
Query: 287 AAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVN 346
AAE++CAL +LH K I+YRDLKPEN LL+++G+LVLTDFGL K+ + T
Sbjct: 199 AAEIACALGYLHEKNIIYRDLKPENLLLDDKGYLVLTDFGLCKEDMQGSKTTS------- 251
Query: 347 QLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQE 406
+ GTPEY APEI+ +PY + DW+ LG ++Y+M+ G PPF +H + +KI +
Sbjct: 252 ---TFCGTPEYLAPEIILKKPYDKTVDWWCLGSVLYEMIFGLPPFYSKDHNEMYDKIINQ 308
Query: 407 KTGARIPSYLSDGFKDYLGALLRKDPTKRWDVDKYWAQDGPXXXXXXXXXXXXXNYIGHF 466
R+ +S + + LL+KD +KR + H
Sbjct: 309 P--LRLKHNISVPCSELITGLLQKDRSKR-----------------LGHRNDFRDIRDHP 349
Query: 467 IFRKIIWKQLLSGDLQKISVGPILPIITDWELAENFDTEFTEKRLDTS 514
F + W +LL+ +L+ P +P + + N EF E ++D S
Sbjct: 350 FFLPVDWDKLLNRELK----APFIPKVKNAMDTSNISKEFVEIQIDPS 393
>Hs5453976 [T] KOG0694 Serine/threonine protein kinase
Length = 706
Score = 185 bits (469), Expect = 2e-46
Identities = 114/355 (32%), Positives = 177/355 (49%), Gaps = 50/355 (14%)
Query: 167 LDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIE 226
++DF+ + LG+G++G +A+K LKK +L+ +D +E
Sbjct: 377 IEDFILHKMLGKGSFGKVFLAEFKKTNQFFAIKALKKDVVLMDDD-------------VE 423
Query: 227 RTFAERTILSQL-EHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAF 285
T E+ +LS EHP + +F +F L+ V++Y+ GG+L YH++ D F
Sbjct: 424 CTMVEKRVLSLAWEHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATF 483
Query: 286 YAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENV 345
YAAE+ L+FLHSKGIVYRDLK +N LL++ GH+ + DFG+ K+++ DA T
Sbjct: 484 YAAEIILGLQFLHSKGIVYRDLKLDNILLDKDGHIKIADFGMCKENMLGDAKT------- 536
Query: 346 NQLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQ 405
+ GTP+Y APEIL G+ Y + DW+S G L+Y+MLIG+ PF G + + + + I+
Sbjct: 537 ---NTFCGTPDYIAPEILLGQKYNHSVDWWSFGVLLYEMLIGQSPFHGQDEEELFHSIRM 593
Query: 406 EKTGARIPSYLSDGFKDYLGALLRKDPTKRWDVDKYWAQDGPXXXXXXXXXXXXXNYIGH 465
+ P +L KD L L ++P KR V Q H
Sbjct: 594 D--NPFYPRWLEKEAKDLLVKLFVREPEKRLGVRGDIRQ--------------------H 631
Query: 466 FIFRKIIWKQLLSGDLQKISVGPILPIITDWELAENFDTEFTEKRLDTSIYDNGI 520
+FR+I W++L ++ P P + NFD EF ++ S D +
Sbjct: 632 PLFREINWEELERKEIDP----PFRPKVKSPFDCSNFDKEFLNEKPRLSFADRAL 682
>Hs4759050 [T] KOG0603 Ribosomal protein S6 kinase
Length = 740
Score = 185 bits (469), Expect = 2e-46
Identities = 134/384 (34%), Positives = 185/384 (47%), Gaps = 62/384 (16%)
Query: 170 FVPIRCLGEGAYGXXXXXXXXXXXXX---YAMKQLKKAEILISEDSIEKDANTTVEKRIE 226
F ++ LG+G++G YAMK LKKA + + + R+
Sbjct: 68 FELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRD-------------RV- 113
Query: 227 RTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFY 286
RT ER IL ++ HP IVKL Y+F KLYL+L ++ GG+LF L ++ E V FY
Sbjct: 114 RTKMERDILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFY 173
Query: 287 AAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVN 346
AEL+ AL LHS GI+YRDLKPEN LL+E GH+ LTDFGLSK+S+ ++
Sbjct: 174 LAELALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESI----------DHEK 223
Query: 347 QLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQE 406
+ YS GT EY APE++ +TQ+ DW+S G L+++ML G PF G + K + I +
Sbjct: 224 KAYSFCGTVEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKA 283
Query: 407 KTGARIPSYLSDGFKDYLGALLRKDPTKRWDVDKYWAQDGPXXXXXXXXXXXXXNYIGHF 466
K G +P +LS + L L +++P R GP H
Sbjct: 284 KLG--MPQFLSPEAQSLLRMLFKRNPANRLGA-------GPDGVEEIKR---------HS 325
Query: 467 IFRKIIWKQLLSGDLQKISVGPILPIITDWELAENFDTEFTEKRLDTSIYDNGIEINNPR 526
F I W +L ++ P P E FD EFT K T GI +
Sbjct: 326 FFSTIDWNKLYRREIHP----PFKPATGRPEDTFYFDPEFTAK---TPKDSPGIPPS--- 375
Query: 527 ATKESAFAGSTDYFKGFSYVASRS 550
A + F+GFS+VA S
Sbjct: 376 -------ANAHQLFRGFSFVAITS 392
Score = 91.3 bits (225), Expect = 4e-18
Identities = 83/311 (26%), Positives = 138/311 (43%), Gaps = 44/311 (14%)
Query: 134 SDKETRDVLSVSSVEETRQLRASSFSKTGAPRVLDDFVPIRCLGEGAYGXXXXXXXXXXX 193
SD E++ + +V +QL +S T V +D +G G+Y
Sbjct: 392 SDDESQAMQTVGVHSIVQQLHRNSIQFTDGYEVKED------IGVGSYSVCKRCIHKATN 445
Query: 194 XXYAMKQLKKAEILISEDSIEKDANTTVEKRIERTFAERTILSQLEHPNIVKLFYSFHDN 253
+A+K + K++ +D +E +L +HPNI+ L + D
Sbjct: 446 MEFAVKIIDKSK---------RDPTEEIE----------ILLRYGQHPNIITLKDVYDDG 486
Query: 254 HKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAAELSCALKFLHSKGIVYRDLKPENCL 313
+Y+V + + GGEL + Q E + ++ +++LH++G+V+RDLKP N L
Sbjct: 487 KYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQGVVHRDLKPSNIL 546
Query: 314 -LNERGH---LVLTDFGLSKKSVFDDAATPEEGENVNQLYSIIGTPEYCAPEILAGEPYT 369
++E G+ + + DFG +K+ E G + Y T + APE+L + Y
Sbjct: 547 YVDESGNPESIRICDFGFAKQ------LRAENGLLMTPCY----TANFVAPEVLKRQGYD 596
Query: 370 QNCDWYSLGCLVYDMLIGKPPFTG---VNHKIILNKIKQEK--TGARIPSYLSDGFKDYL 424
CD +SLG L+Y ML G PF + IL +I K + +SD KD +
Sbjct: 597 AACDIWSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNSVSDTAKDLV 656
Query: 425 GALLRKDPTKR 435
+L DP +R
Sbjct: 657 SKMLHVDPHQR 667
>Hs19923570 [T] KOG0603 Ribosomal protein S6 kinase
Length = 733
Score = 185 bits (469), Expect = 2e-46
Identities = 139/413 (33%), Positives = 201/413 (48%), Gaps = 66/413 (15%)
Query: 143 SVSSVEE---TRQLRASSFSKTGAPRV-LDDFVPIRCLGEGAYGXXXXXXXXXXXXX--- 195
S+S +EE +++ S K G + F ++ LG+G+YG
Sbjct: 28 SLSRLEEEGVVKEIDISHHVKEGFEKADPSQFELLKVLGQGSYGKVFLVRKVKGSDAGQL 87
Query: 196 YAMKQLKKAEILISEDSIEKDANTTVEKRIERTFAERTILSQLEHPNIVKLFYSFHDNHK 255
YAMK LKKA + + + R+ R+ ER IL+++ HP IVKL Y+F K
Sbjct: 88 YAMKVLKKATLKVRD-------------RV-RSKMERDILAEVNHPFIVKLHYAFQTEGK 133
Query: 256 LYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAAELSCALKFLHSKGIVYRDLKPENCLLN 315
LYL+L ++ GG+LF L ++ E V FY AEL+ AL LHS GI+YRDLKPEN LL+
Sbjct: 134 LYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGIIYRDLKPENILLD 193
Query: 316 ERGHLVLTDFGLSKKSVFDDAATPEEGENVNQLYSIIGTPEYCAPEILAGEPYTQNCDWY 375
E GH+ +TDFGLSK+++ D + YS GT EY APE++ +TQ+ DW+
Sbjct: 194 EEGHIKITDFGLSKEAIDHD----------KRAYSFCGTIEYMAPEVVNRRGHTQSADWW 243
Query: 376 SLGCLVYDMLIGKPPFTGVNHKIILNKIKQEKTGARIPSYLSDGFKDYLGALLRKDPTKR 435
S G L+++ML G PF G + K + I + K G +P +LS + L AL +++P R
Sbjct: 244 SFGVLMFEMLTGSLPFQGKDRKETMALILKAKLG--MPQFLSGEAQSLLRALFKRNPCNR 301
Query: 436 WDVDKYWAQDGPXXXXXXXXXXXXXNYIGHFIFRKIIWKQLLSGDLQKISVGPILPIITD 495
DG H F I W L +++ P P +
Sbjct: 302 LGA----GIDGVEEIKR------------HPFFVTIDWNTLYRKEIKP----PFKPAVGR 341
Query: 496 WELAENFDTEFTEKRLDTSIYDNGIEINNPRATKESAFAGSTDYFKGFSYVAS 548
E +FD EFT + T G+ + A + F+GFS+VAS
Sbjct: 342 PEDTFHFDPEFTAR---TPTDSPGVPPS----------ANAHHLFRGFSFVAS 381
Score = 89.4 bits (220), Expect = 1e-17
Identities = 79/295 (26%), Positives = 129/295 (42%), Gaps = 46/295 (15%)
Query: 151 RQLRASSFSKTGAPRVLDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISE 210
+QL ++ T + +D +G G+Y YA+K + K++
Sbjct: 402 QQLHGNNIHFTDGYEIKED------IGVGSYSVCKRCVHKATDTEYAVKIIDKSK----- 450
Query: 211 DSIEKDANTTVEKRIERTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFY 270
+D + +E +L +HPNI+ L + D +YLV++ + GGEL
Sbjct: 451 ----RDPSEEIE----------ILLRYGQHPNIITLKDVYDDGKFVYLVMELMRGGELLD 496
Query: 271 HLKEQGTLDEGTVAFYAAELSCALKFLHSKGIVYRDLKPENCLLNERG----HLVLTDFG 326
+ Q E + ++ + +LHS+G+V+RDLKP N L + + + DFG
Sbjct: 497 RILRQRYFSEREASDVLCTITKTMDYLHSQGVVHRDLKPSNILYRDESGSPESIRVCDFG 556
Query: 327 LSKKSVFDDAATPEEGENVNQLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLI 386
+K+ G + L + T + APE+L + Y CD +SLG L+Y ML
Sbjct: 557 FAKQL--------RAGNGL--LMTPCYTANFVAPEVLKRQGYDAACDIWSLGILLYTMLA 606
Query: 387 GKPPFTG---VNHKIILNKI---KQEKTGARIPSYLSDGFKDYLGALLRKDPTKR 435
G PF + IL +I K +G S +SD KD + +L DP +R
Sbjct: 607 GFTPFANGPDDTPEEILARIGSGKYALSGGNWDS-ISDAAKDVVSKMLHVDPHQR 660
>7300106 [T] KOG0690 Serine/threonine protein kinase
Length = 530
Score = 184 bits (467), Expect = 3e-46
Identities = 130/423 (30%), Positives = 197/423 (45%), Gaps = 57/423 (13%)
Query: 126 LSLNAQGDSDKETRDVLSVSSVEETRQ--LRASSFSKTGAPRV-LDDFVPIRCLGEGAYG 182
+++ +D D+ +++ E + Q ++ ++ + +G +V L++F ++ LG+G +G
Sbjct: 138 VAMTPSEQTDMTDVDMATIAEDELSEQFSVQGTTCNSSGVKKVTLENFEFLKVLGKGTFG 197
Query: 183 XXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIERTFAERTILSQLEHPN 242
YA+K LKK E++I +D + A+T E R+ L HP
Sbjct: 198 KVILCREKATAKLYAIKILKK-EVIIQKDEV---AHTLTESRV---------LKSTNHPF 244
Query: 243 IVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAAELSCALKFLHSKGI 302
++ L YSF N +L V+QY+ GGELF+HL + E FY AE+ AL +LHS+GI
Sbjct: 245 LISLKYSFQTNDRLCFVMQYVNGGELFWHLSHERIFTEDRTRFYGAEIISALGYLHSQGI 304
Query: 303 VYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVNQLYSIIGTPEYCAPEI 362
+YRDLK EN LL++ GH+ + DFGL K+ + T + GTPEY APE+
Sbjct: 305 IYRDLKLENLLLDKDGHIKVADFGLCKEDITYGRTTK----------TFCGTPEYLAPEV 354
Query: 363 LAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQEKTGARIPSYLSDGFKD 422
L Y Q DW+ G ++Y+M+ G+ PF +H ++ I E+ + P ++D K+
Sbjct: 355 LDDNDYGQAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLILVEE--VKFPRNITDEAKN 412
Query: 423 YLGALLRKDPTKRWDVDKYWAQDGPXXXXXXXXXXXXXNYIGHFIFRKIIWKQLLSGDLQ 482
L LL KDP KR K H F I W L+ L+
Sbjct: 413 LLAGLLAKDPKKRLGGGK----------------DDVKEIQAHPFFASINWTDLV---LK 453
Query: 483 KISVGPILPIITDWELAENFDTEFTEKRLDTSIYDNGIEINNPRATKESAFAGSTDYFKG 542
KI P P +T FD EFT +E+ P T F
Sbjct: 454 KIP-PPFKPQVTSDTDTRYFDKEFT---------GESVELTPPDPTGPLGSIAEEPLFPQ 503
Query: 543 FSY 545
FSY
Sbjct: 504 FSY 506
>CE22045 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 580
Score = 183 bits (465), Expect = 5e-46
Identities = 133/404 (32%), Positives = 191/404 (46%), Gaps = 63/404 (15%)
Query: 149 ETRQLRASSFSKTGAPRVLDDFVPIRCLGEGAYGXXXXXXXXXXXXX---YAMKQLKKAE 205
E+ QL AS+ + +DF ++ LG+G YG +AMK L+KA
Sbjct: 62 ESIQLCASAINPPNVRVGPEDFQLLKVLGKGGYGKVFQVRKTTGSDNGQIFAMKVLQKAT 121
Query: 206 ILISEDSIEKDANTTVEKRIERTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPG 265
I+ ++ K T AER IL ++ P I L Y+F KLYL+L+Y+ G
Sbjct: 122 IVRNQ------------KDTAHTKAERNILEAVKSPFICDLLYAFQTGGKLYLILEYLSG 169
Query: 266 GELFYHLKEQGTLDEGTVAFYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDF 325
GELF HL+ +G E FY +E+ +L+ LH +GI+YRDLKPEN LL+ GH+ LTDF
Sbjct: 170 GELFMHLEREGMFMENVAKFYLSEIVVSLEHLHQQGIIYRDLKPENILLDAYGHVKLTDF 229
Query: 326 GLSKKSVFDDAATPEEGENVNQLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDML 385
GL K+ + D T ++ GT EY APEIL + + DW+SLG L++DML
Sbjct: 230 GLCKEEIEGDQKT----------HTFCGTIEYMAPEILMRCGHGKAVDWWSLGALMFDML 279
Query: 386 IGKPPFTGVNHKIILNKIKQEKTGARIPSYLSDGFKDYLGALLRKDPTKRWDVDKYWAQD 445
G PPFT N + ++KI K +P+YLS+ +D + LL++ R A++
Sbjct: 280 TGGPPFTAENRRKTIDKIL--KGRLTLPAYLSNEARDLIKKLLKRHVDTRLGAGLSDAEE 337
Query: 446 GPXXXXXXXXXXXXXNYIGHFIFRKIIWKQLLSGDLQKISVGPILPIITDWELAENFDTE 505
H F+ W + + L+ P P I + E FD
Sbjct: 338 ----------------IKSHAFFKTTDWNLVYARQLE----APFKPNIENDEDTSLFDAR 377
Query: 506 FTEKRLDTSIYDNGIEIN--NPRATKESAFAGSTDYFKGFSYVA 547
FT+ S + +N NP F GF+YVA
Sbjct: 378 FTKMTPVDSPCETNFSLNGDNP--------------FVGFTYVA 407
>At5g62310 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1168
Score = 183 bits (465), Expect = 5e-46
Identities = 110/326 (33%), Positives = 170/326 (51%), Gaps = 36/326 (11%)
Query: 133 DSDKETRDVLSVSSVEETRQLRASSFSKTGAPRV-LDDFVPIRCLGEGAYGXXXXXXXXX 191
DS D S + + R LRAS + R ++DF I+ + GA+G
Sbjct: 716 DSSNAMPDEESSADEDTVRSLRASPLNPRAKDRTSIEDFEIIKPISRGAFGRVFLAKKRA 775
Query: 192 XXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIERTFAERTILSQLEHPNIVKLFYSFH 251
+A+K LKKA D I K+A +E AER IL + +P +V+ FYSF
Sbjct: 776 TGDLFAIKVLKKA------DMIRKNA-------VESILAERNILISVRNPFVVRFFYSFT 822
Query: 252 DNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAAELSCALKFLHSKGIVYRDLKPEN 311
LYLV++Y+ GG+LF L+ G LDE Y AE+ AL++LHS I++RDLKP+N
Sbjct: 823 CRENLYLVMEYLNGGDLFSLLRNLGCLDEDMARIYIAEVVLALEYLHSVNIIHRDLKPDN 882
Query: 312 CLLNERGHLVLTDFGLSKKSVFDDA---------------------ATPEEGENVNQLYS 350
L+N+ GH+ LTDFGLSK + + A +G++ + ++
Sbjct: 883 LLINQDGHIKLTDFGLSKVGLINSTDDLSGESSLGNSGFFAEDGSKAQHSQGKDSRKKHA 942
Query: 351 IIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTG-VNHKIILNKIKQEKTG 409
++GTP+Y APEIL G + + DW+S+G +++++L+G PPF +I N I ++
Sbjct: 943 VVGTPDYLAPEILLGMGHGKTADWWSVGVILFEVLVGIPPFNAETPQQIFENIINRDIPW 1002
Query: 410 ARIPSYLSDGFKDYLGALLRKDPTKR 435
+P +S D + LL ++P +R
Sbjct: 1003 PNVPEEISYEAHDLINKLLTENPVQR 1028
>Hs4502023 [T] KOG0690 Serine/threonine protein kinase
Length = 481
Score = 183 bits (464), Expect = 7e-46
Identities = 116/353 (32%), Positives = 175/353 (48%), Gaps = 45/353 (12%)
Query: 159 SKTGAPRVLDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDAN 218
SK A ++DF ++ LG+G +G YAMK L+K E++I++D + A+
Sbjct: 141 SKARAKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRK-EVIIAKDEV---AH 196
Query: 219 TTVEKRIERTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTL 278
T E R+ L HP + L Y+F + +L V++Y GGELF+HL +
Sbjct: 197 TVTESRV---------LQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVF 247
Query: 279 DEGTVAFYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAAT 338
E FY AE+ AL++LHS+ +VYRD+K EN +L++ GH+ +TDFGL K+ + D A
Sbjct: 248 TEERARFYGAEIVSALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEGISDGAT- 306
Query: 339 PEEGENVNQLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKI 398
+ + GTPEY APE+L Y + DW+ LG ++Y+M+ G+ PF +H+
Sbjct: 307 ---------MKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHER 357
Query: 399 ILNKIKQEKTGARIPSYLSDGFKDYLGALLRKDPTKRWDVDKYWAQDGPXXXXXXXXXXX 458
+ I E+ R P LS K L LL+KDP +R GP
Sbjct: 358 LFELILMEE--IRFPRTLSPEAKSLLAGLLKKDPKQR-------LGGGP---------SD 399
Query: 459 XXNYIGHFIFRKIIWKQLLSGDLQKISVGPILPIITDWELAENFDTEFTEKRL 511
+ H F I W+ + +QK + P P +T FD EFT + +
Sbjct: 400 AKEVMEHRFFLSINWQDV----VQKKLLPPFKPQVTSEVDTRYFDDEFTAQSI 448
>Hs4506055 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 351
Score = 182 bits (462), Expect = 1e-45
Identities = 102/270 (37%), Positives = 148/270 (54%), Gaps = 28/270 (10%)
Query: 167 LDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIE 226
LD F I+ LG G++G YAMK L K +++ K+IE
Sbjct: 41 LDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKL-------------KQIE 87
Query: 227 RTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFY 286
T E+ IL + P +VKL +SF DN LY+V++Y+PGGE+F HL+ G E FY
Sbjct: 88 HTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFY 147
Query: 287 AAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVN 346
AA++ ++LHS ++YRDLKPEN L++++G++ +TDFG +K+
Sbjct: 148 AAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRV-------------KG 194
Query: 347 QLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQE 406
+ +++ GTPEY APEI+ + Y + DW++LG L+Y+M G PPF I KI
Sbjct: 195 RTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSG 254
Query: 407 KTGARIPSYLSDGFKDYLGALLRKDPTKRW 436
K R PS+ S KD L LL+ D TKR+
Sbjct: 255 K--VRFPSHFSSDLKDLLRNLLQVDLTKRF 282
>7297542 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 353
Score = 182 bits (461), Expect = 2e-45
Identities = 103/270 (38%), Positives = 147/270 (54%), Gaps = 28/270 (10%)
Query: 167 LDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIE 226
LDDF I+ LG G++G YAMK L K +++ K++E
Sbjct: 43 LDDFERIKTLGTGSFGRVMIVQHKPTKDYYAMKILDKQKVVKL-------------KQVE 89
Query: 227 RTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFY 286
T E+ IL ++ P +V L Y F DN LY+VL+Y+PGGE+F HL++ G E FY
Sbjct: 90 HTLNEKRILQAIQFPFLVSLRYHFKDNSNLYMVLEYVPGGEMFSHLRKVGRFSEPHSRFY 149
Query: 287 AAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVN 346
AA++ A ++LH ++YRDLKPEN L++ +G+L +TDFG +K+
Sbjct: 150 AAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYLKVTDFGFAKRV-------------KG 196
Query: 347 QLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQE 406
+ +++ GTPEY APEI+ + Y + DW++LG LVY+M G PPF I KI
Sbjct: 197 RTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQPIQIYEKIVSG 256
Query: 407 KTGARIPSYLSDGFKDYLGALLRKDPTKRW 436
K R PS+ KD L LL+ D TKR+
Sbjct: 257 K--VRFPSHFGSDLKDLLRNLLQVDLTKRY 284
>Hs4885549 [T] KOG0690 Serine/threonine protein kinase
Length = 479
Score = 181 bits (459), Expect = 3e-45
Identities = 118/347 (34%), Positives = 169/347 (48%), Gaps = 45/347 (12%)
Query: 165 RVLDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKR 224
+ ++DF ++ LG+G +G YAMK LKK E++I++D + A+T E R
Sbjct: 143 KTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKK-EVIIAKDEV---AHTLTESR 198
Query: 225 IERTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVA 284
+ L HP + L YSF +L V++Y+ GGELF+HL + E
Sbjct: 199 V---------LKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTR 249
Query: 285 FYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGEN 344
FY AE+ AL +LHS IVYRDLK EN +L++ GH+ +TDFGL K+ + DAAT
Sbjct: 250 FYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGI-TDAAT------ 302
Query: 345 VNQLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIK 404
+ + GTPEY APE+L Y + DW+ LG ++Y+M+ G+ PF +H+ + I
Sbjct: 303 ---MKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELIL 359
Query: 405 QEKTGARIPSYLSDGFKDYLGALLRKDPTKRWDVDKYWAQDGPXXXXXXXXXXXXXNYIG 464
E + P LS K L LL KDP KR GP +
Sbjct: 360 ME--DIKFPRTLSSDAKSLLSGLLIKDPNKR-------LGGGP---------DDAKEIMR 401
Query: 465 HFIFRKIIWKQLLSGDLQKISVGPILPIITDWELAENFDTEFTEKRL 511
H F + W+ + L V P P +T FD EFT + +
Sbjct: 402 HSFFSGVNWQDVYDKKL----VPPFKPQVTSETDTRYFDEEFTAQTI 444
>Hs7657526 [T] KOG0603 Ribosomal protein S6 kinase
Length = 745
Score = 181 bits (458), Expect = 3e-45
Identities = 131/382 (34%), Positives = 182/382 (47%), Gaps = 64/382 (16%)
Query: 170 FVPIRCLGEGAYGXXXXXXXXX---XXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIE 226
F ++ LG+G++G YAMK LKKA + + + R+
Sbjct: 73 FELLKVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLKKASLKVRD-------------RV- 118
Query: 227 RTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFY 286
RT ER IL ++ HP IVKL Y+F KLYL+L ++ GG++F L ++ E V FY
Sbjct: 119 RTKMERDILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDVFTRLSKEVLFTEEDVKFY 178
Query: 287 AAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVN 346
AEL+ AL LH GIVYRDLKPEN LL+E GH+ LTDFGLSK+SV +
Sbjct: 179 LAELALALDHLHQLGIVYRDLKPENILLDEIGHIKLTDFGLSKESV----------DQEK 228
Query: 347 QLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQE 406
+ YS GT EY APE++ ++Q+ DW+S G L+++ML G PF G + +N I +
Sbjct: 229 KAYSFCGTVEYMAPEVVNRRGHSQSADWWSYGVLMFEMLTGTLPFQGKDRNETMNMILKA 288
Query: 407 KTGARIPSYLSDGFKDYLGALLRKDPTKRWDVDKYWAQDGPXXXXXXXXXXXXXNYIGHF 466
K G +P +LS + L L +++P R H
Sbjct: 289 KLG--MPQFLSAEAQSLLRMLFKRNPANR------------------LGSEGVEEIKRHL 328
Query: 467 IFRKIIWKQLLSGDLQKISVGPILPIITDWELAENFDTEFTEKRLDTSIYDNGIEINNPR 526
F I W +L ++Q P P + FD EFT K T G+
Sbjct: 329 FFANIDWDKLYKREVQP----PFKPASGKPDDTFCFDPEFTAK---TPKDSPGL------ 375
Query: 527 ATKESAFAGSTDYFKGFSYVAS 548
A A + FKGFS+VA+
Sbjct: 376 ----PASANAHQLFKGFSFVAT 393
Score = 95.1 bits (235), Expect = 2e-19
Identities = 70/211 (33%), Positives = 103/211 (48%), Gaps = 19/211 (9%)
Query: 239 EHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAAELSCALKFLH 298
+HPNI+ L F D +YLV + GGEL + +Q E + +S + +LH
Sbjct: 476 QHPNIITLKDVFDDGRYVYLVTDLMKGGELLDRILKQKCFSEREASDILYVISKTVDYLH 535
Query: 299 SKGIVYRDLKPENCLLNERG----HLVLTDFGLSKKSVFDDAATPEEGENVNQLYSIIGT 354
+G+V+RDLKP N L + + + DFG +K+ GEN L + T
Sbjct: 536 CQGVVHRDLKPSNILYMDESASADSIRICDFGFAKQL---------RGEN-GLLLTPCYT 585
Query: 355 PEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPF-TGVNH--KIILNKIKQEKTGAR 411
+ APE+L + Y CD +SLG L Y ML G PF G N + IL +I K
Sbjct: 586 ANFVAPEVLMQQGYDAACDIWSLGVLFYTMLAGYTPFANGPNDTPEEILLRIGNGKFSLS 645
Query: 412 IPSY--LSDGFKDYLGALLRKDPTKRWDVDK 440
++ +SDG KD L +L DP +R+ ++
Sbjct: 646 GGNWDNISDGAKDLLSHMLHMDPHQRYTAEQ 676
>Hs14735945 [T] KOG0694 Serine/threonine protein kinase
Length = 676
Score = 181 bits (458), Expect = 3e-45
Identities = 116/370 (31%), Positives = 183/370 (49%), Gaps = 54/370 (14%)
Query: 167 LDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIE 226
+++F+ + LG+G++G +A+K LKK +LI +D +E
Sbjct: 346 INNFIFHKVLGKGSFGKVLLGELKGRGEYFAIKALKKDVVLIDDD-------------VE 392
Query: 227 RTFAERTILS-QLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAF 285
T E+ +L+ E+P + L +F L+ V++++ GG+L YH++++G + F
Sbjct: 393 CTMVEKRVLTLAAENPFLTHLICTFQTKDHLFFVMEFLNGGDLMYHIQDKGRFELYRATF 452
Query: 286 YAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENV 345
YAAE+ C L+FLHSKGI+YRDLK +N LL+ GH+ + DFG+ K+++F +
Sbjct: 453 YAAEIMCGLQFLHSKGIIYRDLKLDNVLLDRDGHIKIADFGMCKENIFGE---------- 502
Query: 346 NQLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQ 405
++ + GTP+Y APEIL G YT + DW+S G L+Y+MLIG+ PF G + + I+
Sbjct: 503 SRASTFCGTPDYIAPEILQGLKYTFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESIRV 562
Query: 406 EKTGARIPSYLSDGFKDYLGALLRKDPTKRWDVDKYWAQDGPXXXXXXXXXXXXXNYIGH 465
+ P +++ KD L L ++PTKR V N H
Sbjct: 563 DT--PHYPRWITKESKDILEKLFEREPTKRLGV--------------------TGNIKIH 600
Query: 466 FIFRKIIWKQLLSGDLQKISVGPILPIITDWELAENFDTEFTEKRLDTSIYDNGIEINNP 525
F+ I W L L+ P P + NFD EF ++ S D N
Sbjct: 601 PFFKTINWTLLEKRRLEP----PFRPKVKSPRDYSNFDQEFLNEKARLSYSDK----NLI 652
Query: 526 RATKESAFAG 535
+ +SAFAG
Sbjct: 653 DSMDQSAFAG 662
>Hs4506057 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 351
Score = 179 bits (454), Expect = 1e-44
Identities = 100/270 (37%), Positives = 147/270 (54%), Gaps = 28/270 (10%)
Query: 167 LDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIE 226
L+DF + LG G++G YAMK L K +++ K+IE
Sbjct: 41 LEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKL-------------KQIE 87
Query: 227 RTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFY 286
T E+ IL + P +V+L Y+F DN LY+V++Y+PGGE+F HL+ G E FY
Sbjct: 88 HTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFY 147
Query: 287 AAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVN 346
AA++ ++LHS ++YRDLKPEN L++ +G++ +TDFG +K+
Sbjct: 148 AAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRV-------------KG 194
Query: 347 QLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQE 406
+ +++ GTPEY APEI+ + Y + DW++LG L+Y+M G PPF I KI
Sbjct: 195 RTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSG 254
Query: 407 KTGARIPSYLSDGFKDYLGALLRKDPTKRW 436
K R PS+ S KD L LL+ D TKR+
Sbjct: 255 K--VRFPSHFSSDLKDLLRNLLQVDLTKRF 282
>Hs20127541 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 427
Score = 179 bits (453), Expect = 1e-44
Identities = 126/378 (33%), Positives = 176/378 (46%), Gaps = 55/378 (14%)
Query: 169 DFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIERT 228
DF ++ +G+G YG YA+K L+K IL +K
Sbjct: 94 DFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSIL-------------KKKEQSHI 140
Query: 229 FAERTIL-SQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYA 287
AER++L + HP +V L YSF KLY VL Y+ GGELF+HL+ + E FYA
Sbjct: 141 MAERSVLLKNVRHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYA 200
Query: 288 AELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVNQ 347
AE++ A+ +LHS I+YRDLKPEN LL+ +GH+VLTDFGL K+ V + T
Sbjct: 201 AEVASAIGYLHSLNIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDTTS-------- 252
Query: 348 LYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQEK 407
+ GTPEY APE+L EPY + DW+ LG ++Y+ML G PPF + + I +
Sbjct: 253 --TFCGTPEYLAPEVLRKEPYDRAVDWWCLGAVLYEMLHGLPPFYSQDVSQMYENILHQP 310
Query: 408 TGARIPSYLSDGFKDYLGALLRKDPTKRWDVDKYWAQDGPXXXXXXXXXXXXXNYIGHFI 467
+IP + D L +LL KD +R H
Sbjct: 311 --LQIPGGRTVAACDLLQSLLHKDQRQR-----------------LGSKADFLEIKNHVF 351
Query: 468 FRKIIWKQLLSGDLQKISVGPILPIITDWELAENFDTEFTEKRLDTSIYDNGIEINNPRA 527
F I W L K P P +T ++FD EFT++ + SI
Sbjct: 352 FSPINWDDL----YHKRLTPPFNPNVTGPADLKHFDPEFTQEAVSKSI--------GCTP 399
Query: 528 TKESAFAGSTDYFKGFSY 545
++ +G++ F GFSY
Sbjct: 400 DTVASSSGASSAFLGFSY 417
>CE15475 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 375
Score = 179 bits (453), Expect = 1e-44
Identities = 101/270 (37%), Positives = 148/270 (54%), Gaps = 28/270 (10%)
Query: 167 LDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIE 226
LDDF I+ LG G++G YAMK L K +++ K++E
Sbjct: 49 LDDFDRIKTLGTGSFGRVMLVKHKQSGNYYAMKILDKQKVVKL-------------KQVE 95
Query: 227 RTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFY 286
T E+ IL ++ P +V + +SF DN LY+VL++I GGE+F HL+ G E FY
Sbjct: 96 HTLNEKRILQAIDFPFLVNMTFSFKDNSNLYMVLEFISGGEMFSHLRRIGRFSEPHSRFY 155
Query: 287 AAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVN 346
AA++ A ++LHS ++YRDLKPEN L++ G+L +TDFG +K+
Sbjct: 156 AAQIVLAFEYLHSLDLIYRDLKPENLLIDSTGYLKITDFGFAKRV-------------KG 202
Query: 347 QLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQE 406
+ +++ GTPEY APEI+ + Y + DW++LG L+Y+M G PPF I KI
Sbjct: 203 RTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSG 262
Query: 407 KTGARIPSYLSDGFKDYLGALLRKDPTKRW 436
K + PS+ S+ KD L LL+ D TKR+
Sbjct: 263 K--VKFPSHFSNELKDLLKNLLQVDLTKRY 290
>CE15473 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 359
Score = 179 bits (453), Expect = 1e-44
Identities = 101/270 (37%), Positives = 148/270 (54%), Gaps = 28/270 (10%)
Query: 167 LDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIE 226
LDDF I+ LG G++G YAMK L K +++ K++E
Sbjct: 49 LDDFDRIKTLGTGSFGRVMLVKHKQSGNYYAMKILDKQKVVKL-------------KQVE 95
Query: 227 RTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFY 286
T E+ IL ++ P +V + +SF DN LY+VL++I GGE+F HL+ G E FY
Sbjct: 96 HTLNEKRILQAIDFPFLVNMTFSFKDNSNLYMVLEFISGGEMFSHLRRIGRFSEPHSRFY 155
Query: 287 AAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVN 346
AA++ A ++LHS ++YRDLKPEN L++ G+L +TDFG +K+
Sbjct: 156 AAQIVLAFEYLHSLDLIYRDLKPENLLIDSTGYLKITDFGFAKRV-------------KG 202
Query: 347 QLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQE 406
+ +++ GTPEY APEI+ + Y + DW++LG L+Y+M G PPF I KI
Sbjct: 203 RTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSG 262
Query: 407 KTGARIPSYLSDGFKDYLGALLRKDPTKRW 436
K + PS+ S+ KD L LL+ D TKR+
Sbjct: 263 K--VKFPSHFSNELKDLLKNLLQVDLTKRY 290
>Hs4759052 [T] KOG0603 Ribosomal protein S6 kinase
Length = 809
Score = 178 bits (452), Expect = 2e-44
Identities = 141/412 (34%), Positives = 195/412 (47%), Gaps = 63/412 (15%)
Query: 152 QLRASSFSKTGAPRVLDDFVPIRCLGEGAYGXXXXXXXXXXXXX---YAMKQLKKAEILI 208
+LR ++ + +++F ++ LG GAYG YAMK LKKA I+
Sbjct: 31 ELRTANLTGHAEKVGIENFELLKVLGTGAYGKVFLVRKISGHDTGKLYAMKVLKKATIV- 89
Query: 209 SEDSIEKDANTTVEKRIERTFAERTILSQL-EHPNIVKLFYSFHDNHKLYLVLQYIPGGE 267
+ A TT E T ER +L + + P +V L Y+F KL+L+L YI GGE
Sbjct: 90 ------QKAKTT-----EHTRTERQVLEHIRQSPFLVTLHYAFQTETKLHLILDYINGGE 138
Query: 268 LFYHLKEQGTLDEGTVAFYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGL 327
LF HL ++ E V Y E+ AL+ LH GI+YRD+K EN LL+ GH+VLTDFGL
Sbjct: 139 LFTHLSQRERFTEHEVQIYVGEIVLALEHLHKLGIIYRDIKLENILLDSNGHVVLTDFGL 198
Query: 328 SKKSVFDDAATPEEGENVNQLYSIIGTPEYCAPEILAG--EPYTQNCDWYSLGCLVYDML 385
SK+ V D+ + YS GT EY AP+I+ G + + DW+SLG L+Y++L
Sbjct: 199 SKEFVADE---------TERAYSFCGTIEYMAPDIVRGGDSGHDKAVDWWSLGVLMYELL 249
Query: 386 IGKPPFTGVNHKIILNKIKQE--KTGARIPSYLSDGFKDYLGALLRKDPTKRWDVDKYWA 443
G PFT K +I + K+ P +S KD + LL KDP KR
Sbjct: 250 TGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSALAKDLIQRLLMKDPKKRLGC----- 304
Query: 444 QDGPXXXXXXXXXXXXXNYIGHFIFRKIIWKQLLSGDLQKISVGPILPIITDWELAENFD 503
GP H F+KI W L + K P P+I D NF
Sbjct: 305 --GPRDADEIKE---------HLFFQKINWDDLAA----KKVPAPFKPVIRDELDVSNFA 349
Query: 504 TEFTEKRLDTSIYDNGIEINNPRATKESAFAGSTDYFKGFSYVASRSYLERH 555
EFTE +D + +P A +S S F+G+S+VA +R+
Sbjct: 350 EEFTE--MDPTY--------SPAALPQS----SEKLFQGYSFVAPSILFKRN 387
Score = 111 bits (278), Expect = 3e-24
Identities = 86/271 (31%), Positives = 128/271 (46%), Gaps = 33/271 (12%)
Query: 199 KQLKKAEILISEDSIEKDANTTVE-----KRIE-RTFAERTILSQLE-HPNIVKLFYSFH 251
K L + I + K +N ++ KR+E T E T L E HPNIVKL FH
Sbjct: 430 KPLGEGSFSICRKCVHKKSNQALQVKIISKRMEANTQKEITALKLCEGHPNIVKLHEVFH 489
Query: 252 DNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAAELSCALKFLHSKGIVYRDLKPEN 311
D +LV++ + GGELF L+++ E ++ +L AL +H G+V+RDLKPEN
Sbjct: 490 DQLHTFLVMELLNGGELFDALRKKKHFSETEASYIMRKLVSALSHMHDLGVVHRDLKPEN 549
Query: 312 CLL---NERGHLVLTDFGLSKKSVFDDAATPEEGENVNQLYSIIGTPEYCAPEILAGEPY 368
L N+ + + DFG ++ D+ L + T C PE+L Y
Sbjct: 550 LLFTDENDNLEIKIIDFGFARLKPPDN----------QPLKTPCFTLHSCRPELLNQNGY 599
Query: 369 TQNCDWYSLGCLVYDMLIGKPPFTGVNHKI-------ILNKIKQEKTGARIPSY--LSDG 419
++CD +SLG ++Y ML G+ PF + + I+ KIK+ ++ +S
Sbjct: 600 DESCDLWSLGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSFEGEAWKNVSQE 659
Query: 420 FKDYLGALLRKDPTKRWDVD----KYWAQDG 446
KD + LL DP KR + W QDG
Sbjct: 660 AKDLIQGLLTVDPNKRLKMSGLRYNEWLQDG 690
>Hs4826948 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 358
Score = 178 bits (451), Expect = 2e-44
Identities = 112/353 (31%), Positives = 178/353 (49%), Gaps = 59/353 (16%)
Query: 167 LDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIE 226
L DF + +G G +G +A+K + +++ K+ +
Sbjct: 46 LQDFDTLATVGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRL-------------KQEQ 92
Query: 227 RTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFY 286
E+++L ++ HP +++LF+++HD LY++++Y+PGGELF +L+ +G T FY
Sbjct: 93 HVHNEKSVLKEVSHPFLIRLFWTWHDERFLYMLMEYVPGGELFSYLRNRGRFSSTTGLFY 152
Query: 287 AAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVN 346
+AE+ CA+++LHSK IVYRDLKPEN LL+ GH+ LTDFG +KK V+
Sbjct: 153 SAEIICAIEYLHSKEIVYRDLKPENILLDRDGHIKLTDFGFAKKL-------------VD 199
Query: 347 QLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPF-----TGVNHKIILN 401
+ +++ GTPEY APE++ + + + DW++LG L+++ML G PPF G+ KI+
Sbjct: 200 RTWTLCGTPEYLAPEVIQSKGHGRAVDWWALGILIFEMLSGFPPFFDDNPFGIYQKILAG 259
Query: 402 KIKQEKTGARIPSYLSDGFKDYLGALLRKDPTKRWDVDKYWAQDGPXXXXXXXXXXXXXN 461
KI P +L KD + LL D T+R K A D
Sbjct: 260 KID-------FPRHLDFHVKDLIKKLLVVDRTRRLGNMKNGANDVKH------------- 299
Query: 462 YIGHFIFRKIIWKQLLSGDLQKISVGPILPIITDWELAENFDTEFTEKRLDTS 514
H FR + W+ + L+ PI+P I NF+T + E DT+
Sbjct: 300 ---HRWFRSVDWEAVPQRKLKP----PIVPKIAGDGDTSNFET-YPENDWDTA 344
>Hs5453970 [T] KOG0694 Serine/threonine protein kinase
Length = 676
Score = 177 bits (450), Expect = 3e-44
Identities = 115/370 (31%), Positives = 182/370 (49%), Gaps = 54/370 (14%)
Query: 167 LDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIE 226
+++F+ + LG+G++G A+K LKK +LI +D +E
Sbjct: 346 INNFIFHKVLGKGSFGKVLLGELKGRGEYSAIKALKKDVVLIDDD-------------VE 392
Query: 227 RTFAERTILS-QLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAF 285
T E+ +L+ E+P + L +F L+ V++++ GG+L YH++++G + F
Sbjct: 393 CTMVEKRVLTLAAENPFLTHLICTFQTKDHLFFVMEFLNGGDLMYHIQDKGRFELYRATF 452
Query: 286 YAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENV 345
YAAE+ C L+FLHSKGI+YRDLK +N LL+ GH+ + DFG+ K+++F +
Sbjct: 453 YAAEIMCGLQFLHSKGIIYRDLKLDNVLLDRDGHIKIADFGMCKENIFGE---------- 502
Query: 346 NQLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQ 405
++ + GTP+Y APEIL G YT + DW+S G L+Y+MLIG+ PF G + + I+
Sbjct: 503 SRASTFCGTPDYIAPEILQGLKYTFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESIRV 562
Query: 406 EKTGARIPSYLSDGFKDYLGALLRKDPTKRWDVDKYWAQDGPXXXXXXXXXXXXXNYIGH 465
+ P +++ KD L L ++PTKR + N H
Sbjct: 563 DT--PHYPRWITKESKDILEKLFEREPTKRLGM--------------------TGNIKIH 600
Query: 466 FIFRKIIWKQLLSGDLQKISVGPILPIITDWELAENFDTEFTEKRLDTSIYDNGIEINNP 525
F+ I W L L+ P P + NFD EF ++ S D N
Sbjct: 601 PFFKTINWTLLEKRRLEP----PFRPKVKSPRDYSNFDQEFLNEKARLSYSDK----NLI 652
Query: 526 RATKESAFAG 535
+ +SAFAG
Sbjct: 653 DSMDQSAFAG 662
>7302860 [T] KOG0696 Serine/threonine protein kinase
Length = 679
Score = 177 bits (449), Expect = 4e-44
Identities = 123/445 (27%), Positives = 212/445 (47%), Gaps = 66/445 (14%)
Query: 113 NKFVVNPAQHTIRLSLNAQG--------DSDKETRDVLSVSSVEETRQLRASSFSKTGAP 164
++ + NP +L +G D +++ + S ++ +R+ + + T +
Sbjct: 282 SEIIKNPTNGWFKLLTQDEGEYYNVPCADDEQDLLKLKQKPSQKKPMVMRSDTNTHTSSK 341
Query: 165 RVL---DDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTV 221
+ + DF I+ LG+G++G YA+K LKK +++I +D +E T +
Sbjct: 342 KDMIRATDFNFIKVLGKGSFGKVLLAERKGSEELYAIKILKK-DVIIQDDDVEC---TMI 397
Query: 222 EKRIERTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEG 281
EKR+ + + P +V+L F +L+ V++Y+ GG+L + +++ G E
Sbjct: 398 EKRV--------LALGEKPPFLVQLHSCFQTMDRLFFVMEYVNGGDLMFQIQQFGKFKEP 449
Query: 282 TVAFYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEE 341
FYAAE++ L FLH+KGI+YRDLK +N LL+ GH+ + DFG+ K+++ D T
Sbjct: 450 VAVFYAAEIAAGLFFLHTKGILYRDLKLDNVLLDADGHVKIADFGMCKENIVGDKTTK-- 507
Query: 342 GENVNQLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILN 401
+ GTP+Y APEI+ +PY ++ DW++ G L+Y+ML+G+PPF G + + +
Sbjct: 508 --------TFCGTPDYIAPEIILYQPYGKSVDWWAYGVLLYEMLVGQPPFDGEDEEELFA 559
Query: 402 KIKQEKTGARIPSYLSDGFKDYLGALLRKDPTKRWDVDKYWAQDGPXXXXXXXXXXXXXN 461
I P LS K+ L K P KR +D
Sbjct: 560 AITDHNVS--YPKSLSKEAKEACKGFLTKQPNKRLGCGSSGEEDVRL------------- 604
Query: 462 YIGHFIFRKIIWKQLLSGDLQKISVGPILPIITDWELAENFDTEFTEKRLDTSIYDNGIE 521
H FR+I W+++ + ++Q P P I + NFD +FT ++ D + D
Sbjct: 605 ---HPFFRRIDWEKIENREVQP----PFKPKIKHRKDVSNFDKQFTSEKTDLTPTDKVFM 657
Query: 522 INNPRATKESAFAGSTDYFKGFSYV 546
+N ++ F GFSY+
Sbjct: 658 MNLDQSE-----------FVGFSYM 671
>At1g03920 [R] KOG0605 NDR and related serine/threonine kinases
Length = 569
Score = 177 bits (448), Expect = 5e-44
Identities = 125/400 (31%), Positives = 195/400 (48%), Gaps = 69/400 (17%)
Query: 63 LPPNTYEEEALISDTEEQAEMMSGFLVPPDSGESKQSQTKEPARRRSSLYNKFVVNPAQH 122
LPP + EAL + T+++ ++ + + + E RR++L K
Sbjct: 50 LPPLGGDGEALSNSTKQKVAAAKQYI--ENHYKEQMKNLNERKERRTTLEKKL------- 100
Query: 123 TIRLSLNAQGD-SDKETRDVLSVSSVEETRQLRASSFSKTGAPRVLDDFVPIRCLGEGAY 181
A D +++ +++ +ET +R K GA DDF + +G+GA+
Sbjct: 101 -------ADADVCEEDQTNLMKFLEKKETEYMRLQRH-KMGA----DDFELLTMIGKGAF 148
Query: 182 GXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIERTFAERTILSQLEHP 241
G +AMK+LKK+E+L ++E AER +L++++
Sbjct: 149 GEVRVVREINTGHVFAMKKLKKSEMLR-------------RGQVEHVRAERNLLAEVDSN 195
Query: 242 NIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAAELSCALKFLHSKG 301
IVKL+ SF DN LYL+++Y+PGG++ L + TL E FY AE A++ +H++
Sbjct: 196 CIVKLYCSFQDNEYLYLIMEYLPGGDMMTLLMRKDTLSEDEAKFYIAESVLAIESIHNRN 255
Query: 302 IVYRDLKPENCLLNERGHLVLTDFGLSKK---SVFDD-----------------AATPEE 341
++RD+KP+N LL+ GHL L+DFGL K SV D + TP+
Sbjct: 256 YIHRDIKPDNLLLDRYGHLRLSDFGLCKPLDCSVIDGEDFTVGNAGSGGGSESVSTTPKR 315
Query: 342 GENVNQL-----------YSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPP 390
+ QL YS +GTP+Y APE+L + Y CDW+SLG ++Y+ML+G PP
Sbjct: 316 SQQ-EQLEHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPP 374
Query: 391 FTGVNHKIILNKIKQEKTGARIP--SYLSDGFKDYLGALL 428
F + KI KT + P S LS G +D +G LL
Sbjct: 375 FYADDPMSTCRKIVNWKTHLKFPEESRLSRGARDLIGKLL 414
>YPL203w [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 380
Score = 176 bits (447), Expect = 6e-44
Identities = 117/366 (31%), Positives = 176/366 (47%), Gaps = 49/366 (13%)
Query: 150 TRQLRASSFSKTGAPRVLDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILIS 209
T QL S G L DF +R LG G++G YA+K LKK +++
Sbjct: 51 TSQLPQKSLVSKGK-YTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKQQVVKM 109
Query: 210 EDSIEKDANTTVEKRIERTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELF 269
K++E T ER +L +EHP +++++ +F D +++V+ YI GGELF
Sbjct: 110 -------------KQVEHTNDERRMLKLVEHPFLIRMWGTFQDARNIFMVMDYIEGGELF 156
Query: 270 YHLKEQGTLDEGTVAFYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSK 329
L++ FYAAE+ AL++LH+ I+YRDLKPEN LL+ GH+ +TDFG +K
Sbjct: 157 SLLRKSQRFPNPVAKFYAAEVILALEYLHAHNIIYRDLKPENILLDRNGHIKITDFGFAK 216
Query: 330 KSVFDDAATPEEGENVNQLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKP 389
E +++ GTP+Y APE++ +PY ++ DW+SLG L+Y+ML G
Sbjct: 217 -------------EVQTVTWTLCGTPDYIAPEVITTKPYNKSVDWWSLGVLIYEMLAGYT 263
Query: 390 PFTGVNHKIILNKIKQEKTGARIPSYLSDGFKDYLGALLRKDPTKRWDVDKYWAQDGPXX 449
PF KI Q K P Y D L L+ D T+R
Sbjct: 264 PFYDTTPMKTYEKILQGK--VVYPPYFHPDVVDLLSKLITADLTRR-------------- 307
Query: 450 XXXXXXXXXXXNYIGHFIFRKIIWKQLLSGDLQKISVGPILPIITDWELAENFDTEFTEK 509
+ H F +++W++LL+ D++ PI I D L FD ++ E+
Sbjct: 308 --IGNLQSGSRDIKAHPWFSEVVWERLLAKDIETPYEPPITSGIGDTSL---FD-QYPEE 361
Query: 510 RLDTSI 515
+LD I
Sbjct: 362 QLDYGI 367
>YJL164c [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 397
Score = 176 bits (447), Expect = 6e-44
Identities = 117/398 (29%), Positives = 198/398 (49%), Gaps = 50/398 (12%)
Query: 92 DSGESKQSQTKEPARRRSSLYNKFVVNPAQHTIRLSLNAQGDSDKETRDVLSVSSVEETR 151
D + ++SQ E + R ++ + + +K + ++ + E+ +
Sbjct: 15 DDRQGEESQKGETSERETT-----ATESGNESKSVEKEGGETQEKPKQPHVTYYNEEQYK 69
Query: 152 QLRASSFSKTGAPRVLDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISED 211
Q A + G+ V +F +R LG G++G YAMK LKK EI++
Sbjct: 70 QFIAQARVTVGSI-VYKNFQILRTLGTGSFGRVHLIRSRHNGRYYAMKVLKK-EIVVRL- 126
Query: 212 SIEKDANTTVEKRIERTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYH 271
K++E T ER +LS + HP I++++ +F D ++++++ YI GGELF
Sbjct: 127 -----------KQVEHTNDERLMLSIVTHPFIIRMWGTFQDAQQIFMIMDYIEGGELFSL 175
Query: 272 LKEQGTLDEGTVAFYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKS 331
L++ FYAAE+ AL++LHSK I+YRDLKPEN LL++ GH+ +TDFG +K
Sbjct: 176 LRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAK-- 233
Query: 332 VFDDAATPEEGENVNQLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPF 391
P+ Y++ GTP+Y APE+++ +PY ++ DW+S G L+Y+ML G PF
Sbjct: 234 -----YVPD------VTYTLCGTPDYIAPEVVSTKPYNKSIDWWSFGILIYEMLAGYTPF 282
Query: 392 TGVNHKIILNKIKQEKTGARIPSYLSDGFKDYLGALLRKDPTKRWDVDKYWAQDGPXXXX 451
N KI + R P + ++ KD L L+ +D ++R + +D
Sbjct: 283 YDSNTMKTYEKILNAE--LRFPPFFNEDVKDLLSRLITRDLSQRLGNLQNGTED------ 334
Query: 452 XXXXXXXXXNYIGHFIFRKIIWKQLLSGDLQKISVGPI 489
H F++++W++LLS +++ PI
Sbjct: 335 ----------VKNHPWFKEVVWEKLLSRNIETPYEPPI 362
>Hs4885061 [T] KOG0690 Serine/threonine protein kinase
Length = 480
Score = 176 bits (447), Expect = 6e-44
Identities = 118/383 (30%), Positives = 178/383 (45%), Gaps = 53/383 (13%)
Query: 167 LDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIE 226
+++F ++ LG+G +G YAMK LKK E+++++D +
Sbjct: 147 MNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKK-EVIVAKDEVA------------ 193
Query: 227 RTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFY 286
T E +L HP + L YSF + +L V++Y GGELF+HL + E FY
Sbjct: 194 HTLTENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFY 253
Query: 287 AAELSCALKFLHS-KGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENV 345
AE+ AL +LHS K +VYRDLK EN +L++ GH+ +TDFGL K+ + D A
Sbjct: 254 GAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGAT-------- 305
Query: 346 NQLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQ 405
+ + GTPEY APE+L Y + DW+ LG ++Y+M+ G+ PF +H+ + I
Sbjct: 306 --MKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILM 363
Query: 406 EKTGARIPSYLSDGFKDYLGALLRKDPTKRWDVDKYWAQDGPXXXXXXXXXXXXXNYIGH 465
E+ R P L K L LL+KDP +R A++ + H
Sbjct: 364 EE--IRFPRTLGPEAKSLLSGLLKKDPKQRLGGGSEDAKE----------------IMQH 405
Query: 466 FIFRKIIWKQLLSGDLQKISVGPILPIITDWELAENFDTEFTEKRLDTSIYDNGIEINNP 525
F I+W+ + L P P +T FD EFT + + + D
Sbjct: 406 RFFAGIVWQHVYEKKLSP----PFKPQVTSETDTRYFDEEFTAQMITITPPDQD------ 455
Query: 526 RATKESAFAGSTDYFKGFSYVAS 548
+ E + +F FSY AS
Sbjct: 456 -DSMECVDSERRPHFPQFSYSAS 477
>Hs15619015 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 351
Score = 176 bits (446), Expect = 8e-44
Identities = 99/269 (36%), Positives = 149/269 (54%), Gaps = 28/269 (10%)
Query: 168 DDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIER 227
D F +R LG G++G YAMK L K +++ K++E
Sbjct: 42 DQFERLRTLGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKM-------------KQVEH 88
Query: 228 TFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYA 287
E+ IL ++ P +VKL +SF DN LYLV++Y+PGGE+F L+ G E FYA
Sbjct: 89 ILNEKRILQAIDFPFLVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQRVGRFSEPHACFYA 148
Query: 288 AELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVNQ 347
A++ A+++LHS +++RDLKPEN L++++G+L +TDFG +K+ +
Sbjct: 149 AQVVLAVQYLHSLDLIHRDLKPENLLIDQQGYLQVTDFGFAKRV-------------KGR 195
Query: 348 LYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQEK 407
+++ GTPEY APEI+ + Y + DW++LG L+Y+M +G PPF I KI +
Sbjct: 196 TWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAVGFPPFYADQPIQIYEKIVSGR 255
Query: 408 TGARIPSYLSDGFKDYLGALLRKDPTKRW 436
R PS LS K L +LL+ D TKR+
Sbjct: 256 --VRFPSKLSSDLKHLLRSLLQVDLTKRF 282
>CE18169 [T] KOG0603 Ribosomal protein S6 kinase
Length = 797
Score = 176 bits (446), Expect = 8e-44
Identities = 140/468 (29%), Positives = 210/468 (43%), Gaps = 88/468 (18%)
Query: 99 SQTKEPARRRSSLYNKF-----VVNPAQHTIRLSLNAQGDSDKETRDVLSVSSVEETRQL 153
S +P S N F ++ P + +N + DS ET ++
Sbjct: 41 SMRSDPTDCSSDTTNTFHSSIHIIQPPPNNGFRLMNWKTDSSSET-------------EI 87
Query: 154 RASSFSKTGAPRVLDDFVPIRCLGEGAYGXXXXXXXXXXXXX---YAMKQLKKAEILISE 210
K G F ++ LG+G++G YAMK LKKA + + +
Sbjct: 88 DIGDVRKCGEKADPRQFELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKVLKKATLKVRD 147
Query: 211 DSIEKDANTTVEKRIERTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFY 270
+RT ER IL+ + HP IVKL Y+F KLYL+L ++ GG+LF
Sbjct: 148 R--------------QRTKLERNILAHISHPFIVKLHYAFQTEGKLYLILDFLRGGDLFT 193
Query: 271 HLKEQGTLDEGTVAFYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKK 330
L ++ E V FY AEL+ AL+ LHS GIVYRDLKPEN LL+ GH+ +TDFGLSK+
Sbjct: 194 RLSKEVMFTEDDVKFYLAELTLALEHLHSLGIVYRDLKPENILLDADGHIKVTDFGLSKE 253
Query: 331 SVFDDAATPEEGENVNQLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPP 390
++ + T YS GT EY APE++ ++ D++SLG L+++ML G P
Sbjct: 254 AIDSEKKT----------YSFCGTVEYMAPEVINRRGHSMAADFWSLGVLMFEMLTGHLP 303
Query: 391 FTGVNHKIILNKIKQEKTGARIPSYLSDGFKDYLGALLRKDPTKRWDVDKYWAQDGPXXX 450
F G + + +I + K +P +L+ + L AL +++ R GP
Sbjct: 304 FQGRDRNDTMTQILKAKLS--MPHFLTQEAQSLLRALFKRNSQNRLGA-------GPDGV 354
Query: 451 XXXXXXXXXXNYIGHFIFRKIIWKQLLSGDLQKISVGPILPIITDWELAENFDTEFTEKR 510
H F KI + +LL+ ++ P P ++ + FD EFT+
Sbjct: 355 EEIKR---------HAFFAKIDFVKLLNKEIDP----PFKPALSTVDSTSYFDPEFTK-- 399
Query: 511 LDTSIYDNGIEINNPRATKES----AFAGSTDYFKGFSYVASRSYLER 554
R K+S A A + F+GFS+V++ ER
Sbjct: 400 ---------------RTPKDSPALPASANGHEIFRGFSFVSNAVMEER 432
Score = 95.9 bits (237), Expect = 1e-19
Identities = 88/304 (28%), Positives = 135/304 (43%), Gaps = 42/304 (13%)
Query: 145 SSVEETRQLRASSFSKTGAPRV---LDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQL 201
++V E R+L A S + DD+ + +G GA+ YA+K +
Sbjct: 426 NAVMEERKLIAKSVRSVPTAKTNPFTDDYEILEKIGNGAHSVVHKCQMKATRRKYAVKIV 485
Query: 202 KKAEILISEDSIEKDANTTVEKRIERTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQ 261
KKA DA V+ +L H +VKLF + D +Y++ +
Sbjct: 486 KKAVF---------DATEEVD----------ILLRHSHHQFVVKLFDVYEDETAIYMIEE 526
Query: 262 YIPGGELFYHLKEQGTL-DEGTVAFYAAELSCALKFLHSKGIVYRDLKPENCLL----NE 316
GGEL L + +L E VA A L A+++LHS+ + +RDL N L +
Sbjct: 527 LCEGGELLDKLVNKKSLGSEKEVAAIMANLLNAVQYLHSQQVAHRDLTAANILFALKDGD 586
Query: 317 RGHLVLTDFGLSKKSVFDDAATPEEGENVNQLYSIIGTPEYCAPEILAGEPYTQNCDWYS 376
L + DFG +K+S E G + Y T ++ APE+L + Y ++CD +S
Sbjct: 587 PSSLRIVDFGFAKQS------RAENGMLMTPCY----TAQFVAPEVLRKQGYDRSCDVWS 636
Query: 377 LGCLVYDMLIGKPPFT-GVNH--KIILNKIKQEKTGARIPSY--LSDGFKDYLGALLRKD 431
LG L++ ML G PF G N IL ++ K P + +SD KD + +L D
Sbjct: 637 LGVLLHTMLTGCTPFAMGPNDTPDQILQRVGDGKISMTHPVWDTISDEAKDLVRKMLDVD 696
Query: 432 PTKR 435
P +R
Sbjct: 697 PNRR 700
>CE13014 [T] KOG0603 Ribosomal protein S6 kinase
Length = 740
Score = 176 bits (445), Expect = 1e-43
Identities = 127/392 (32%), Positives = 189/392 (47%), Gaps = 70/392 (17%)
Query: 170 FVPIRCLGEGAYGXXXXXXXXXXXXX---YAMKQLKKAEILISEDSIEKDANTTVEKRIE 226
F ++ LG+G++G YAMK LKKA + + + +
Sbjct: 47 FELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKVLKKATLKVRDR--------------Q 92
Query: 227 RTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFY 286
RT ER IL+ + HP IVKL Y+F KLYL+L ++ GG+LF L ++ E V FY
Sbjct: 93 RTKLERNILAHISHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEDDVKFY 152
Query: 287 AAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVN 346
AEL+ AL+ LHS GIVYRDLKPEN LL+ GH+ +TDFGLSK+++ + T
Sbjct: 153 LAELTLALEHLHSLGIVYRDLKPENILLDADGHIKVTDFGLSKEAIDSEKKT-------- 204
Query: 347 QLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQE 406
YS GT EY APE++ ++ D++SLG L+++ML G PF G + + +I +
Sbjct: 205 --YSFCGTVEYMAPEVINRRGHSMAADFWSLGVLMFEMLTGHLPFQGRDRNDTMTQILKA 262
Query: 407 KTGARIPSYLSDGFKDYLGALLRKDPTKRWDVDKYWAQDGPXXXXXXXXXXXXXNYIGHF 466
K +P +L+ + L AL +++ R GP H
Sbjct: 263 KLS--MPHFLTQEAQSLLRALFKRNSQNRLGA-------GPDGVEEIKR---------HA 304
Query: 467 IFRKIIWKQLLSGDLQKISVGPILPIITDWELAENFDTEFTEKRLDTSIYDNGIEINNPR 526
F KI + +LL+ ++ P P ++ + FD EFT+ R
Sbjct: 305 FFAKIDFVKLLNKEIDP----PFKPALSTVDSTSYFDPEFTK-----------------R 343
Query: 527 ATKES----AFAGSTDYFKGFSYVASRSYLER 554
K+S A A + F+GFS+V++ ER
Sbjct: 344 TPKDSPALPASANGHEIFRGFSFVSNAVMEER 375
Score = 95.9 bits (237), Expect = 1e-19
Identities = 88/304 (28%), Positives = 135/304 (43%), Gaps = 42/304 (13%)
Query: 145 SSVEETRQLRASSFSKTGAPRV---LDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQL 201
++V E R+L A S + DD+ + +G GA+ YA+K +
Sbjct: 369 NAVMEERKLIAKSVRSVPTAKTNPFTDDYEILEKIGNGAHSVVHKCQMKATRRKYAVKIV 428
Query: 202 KKAEILISEDSIEKDANTTVEKRIERTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQ 261
KKA DA V+ +L H +VKLF + D +Y++ +
Sbjct: 429 KKAVF---------DATEEVD----------ILLRHSHHQFVVKLFDVYEDETAIYMIEE 469
Query: 262 YIPGGELFYHLKEQGTL-DEGTVAFYAAELSCALKFLHSKGIVYRDLKPENCLL----NE 316
GGEL L + +L E VA A L A+++LHS+ + +RDL N L +
Sbjct: 470 LCEGGELLDKLVNKKSLGSEKEVAAIMANLLNAVQYLHSQQVAHRDLTAANILFALKDGD 529
Query: 317 RGHLVLTDFGLSKKSVFDDAATPEEGENVNQLYSIIGTPEYCAPEILAGEPYTQNCDWYS 376
L + DFG +K+S E G + Y T ++ APE+L + Y ++CD +S
Sbjct: 530 PSSLRIVDFGFAKQS------RAENGMLMTPCY----TAQFVAPEVLRKQGYDRSCDVWS 579
Query: 377 LGCLVYDMLIGKPPFT-GVNH--KIILNKIKQEKTGARIPSY--LSDGFKDYLGALLRKD 431
LG L++ ML G PF G N IL ++ K P + +SD KD + +L D
Sbjct: 580 LGVLLHTMLTGCTPFAMGPNDTPDQILQRVGDGKISMTHPVWDTISDEAKDLVRKMLDVD 639
Query: 432 PTKR 435
P +R
Sbjct: 640 PNRR 643
>Hs20070247_2 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 378
Score = 176 bits (445), Expect = 1e-43
Identities = 124/383 (32%), Positives = 183/383 (47%), Gaps = 62/383 (16%)
Query: 169 DFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIERT 228
DF ++ +G+G++G YA+K L+K +L N +K I
Sbjct: 43 DFDFLKVIGKGSFGKVLLAKRKLDGKVYAVKVLQKKIVL----------NRKEQKHI--- 89
Query: 229 FAERTIL-SQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYA 287
AER +L ++HP +V L YSF KLY VL ++ GGELF+HL+ + + E FYA
Sbjct: 90 MAERNVLLKNVKHPFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEHRARFYA 149
Query: 288 AELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSV-FDDAATPEEGENVN 346
AE++ AL +LHS IVYRDLKPEN L++ GH+VLTDFGL K+ + D T
Sbjct: 150 AEIASALGYLHSIKIVYRDLKPENILVDSVGHVVLTDFGLCKEGIAISDTTT-------- 201
Query: 347 QLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPF----TGVNHKIILNK 402
+ GTPEY APE++ +PY DW+ LG ++Y+ML G PPF + IL+K
Sbjct: 202 ---TFCGTPEYLAPEVIRKQPYDNTVDWWCLGAVLYEMLYGLPPFYCRDVAEMYDNILHK 258
Query: 403 IKQEKTGARIPSYLSDGFKDYLGALLRKDPTKRWDVDKYWAQDGPXXXXXXXXXXXXXNY 462
+ G + ++ L LL KD R + + +
Sbjct: 259 PLSLRPGVSLRAW------SILEELLEKDRQNRLGAKEDFLE-----------------I 295
Query: 463 IGHFIFRKIIWKQLLSGDLQKISVGPILPIITDWELAENFDTEFTEKRLDTSIYDNGIEI 522
H F + W L +QK P P + + NFDT FTE+ + S+ +
Sbjct: 296 QNHPFFESLSWADL----VQKKIPPPFNPNVAGPDDIRNFDTAFTEETVPYSVC-----V 346
Query: 523 NNPRATKESAFAGSTDYFKGFSY 545
++ + ++ + D F GFSY
Sbjct: 347 SSDYSIVNASVLEADDAFVGFSY 369
>Hs4506067 [T] KOG0696 Serine/threonine protein kinase
Length = 672
Score = 175 bits (444), Expect = 1e-43
Identities = 123/381 (32%), Positives = 184/381 (48%), Gaps = 58/381 (15%)
Query: 167 LDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIE 226
L DF + LG+G++G YA+K LKK +++I +D +E T VEKR+
Sbjct: 336 LTDFNFLMVLGKGSFGKVMLADRKGTEELYAIKILKK-DVVIQDDDVEC---TMVEKRV- 390
Query: 227 RTFAERTILSQLEHPNIVKLFYS-FHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAF 285
L+ L+ P + +S F +LY V++Y+ GG+L YH+++ G E F
Sbjct: 391 --------LALLDKPPFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVF 442
Query: 286 YAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENV 345
YAAE+S L FLH +GI+YRDLK +N +L+ GH+ + DFG+ K+ + D T
Sbjct: 443 YAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIADFGMCKEHMMDGVTT------- 495
Query: 346 NQLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQ 405
+ GTP+Y APEI+A +PY ++ DW++ G L+Y+ML G+PPF G + + I +
Sbjct: 496 ---RTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIME 552
Query: 406 EKTGARIPSYLSDGFKDYLGALLRKDPTKRWDVDKYWAQDGPXXXXXXXXXXXXXNYIGH 465
P LS L+ K P KR +D H
Sbjct: 553 HNVS--YPKSLSKEAVSICKGLMTKHPAKRLGCGPEGERD----------------VREH 594
Query: 466 FIFRKIIWKQLLSGDLQKISVGPILPIITDWELAENFDTEFTEKRLDTSIYDNGIEINNP 525
FR+I W++L + ++Q P P + + AENFD FT G + P
Sbjct: 595 AFFRRIDWEKLENREIQP----PFKPKVCG-KGAENFDKFFT----------RGQPVLTP 639
Query: 526 RATKESAFAGSTDYFKGFSYV 546
A +D F+GFSYV
Sbjct: 640 PDQLVIANIDQSD-FEGFSYV 659
>CE29092 [T] KOG0694 Serine/threonine protein kinase
Length = 707
Score = 175 bits (444), Expect = 1e-43
Identities = 126/422 (29%), Positives = 201/422 (46%), Gaps = 56/422 (13%)
Query: 127 SLNAQGDSDKETRDVLSVSSVEETRQLRASSFSKT-GAPRVLDDFVPIRCLGEGAYGXXX 185
S + G S+ E L S +++ + S SK G + DF ++ LG+G++G
Sbjct: 334 STDISGSSNSENSGYLQQISEDDSGTTSSRSASKVPGGTLSIHDFTFMKVLGKGSFGKVM 393
Query: 186 XXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIERTFAERTILS-QLEHPNIV 244
YA+K LKK ++++ +D +E T E+ ILS +HP +
Sbjct: 394 LAERKGTDEVYAIKILKK-DVIVQDDDVEC------------TMCEKRILSLAAKHPFLT 440
Query: 245 KLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAAELSCALKFLHSKGIVY 304
L SF + +L+ V++Y+ GG+L + ++ DE FYAAE++CAL+FLH ++Y
Sbjct: 441 ALHSSFQTSDRLFFVMEYVNGGDLMFQIQRARKFDESRARFYAAEVTCALQFLHRNDVIY 500
Query: 305 RDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVNQLYSIIGTPEYCAPEILA 364
RDLK +N LL+ GH L DFG+ K+ + D N + GTP+Y APEIL
Sbjct: 501 RDLKLDNILLDAEGHCRLADFGMCKEGINKD----------NLTSTFCGTPDYIAPEILQ 550
Query: 365 GEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQEKTGARIPSYLSDGFKDYL 424
Y + DW++LG L+Y+M+ G+PPF N + I + P +LS + L
Sbjct: 551 EMEYGVSVDWWALGVLMYEMMAGQPPFEADNEDDLFEAILND--DVLYPVWLSKEAVNIL 608
Query: 425 GALLRKDPTKRWDVDKYWAQDGPXXXXXXXXXXXXXNYIGHFIFRKIIWKQLLSGDLQKI 484
A + K+ KR + +Q G H FR+I W L S ++
Sbjct: 609 KAFMTKNAGKR--LGCVVSQGGEDAIR------------AHPFFREIDWDALESRQVKP- 653
Query: 485 SVGPILPIITDWELAENFDTEFTEKRLDTSIYDNGIEINNPRATKESAFAGSTDYFKGFS 544
P P I A NFD++FT++ + + ++P + A + D F+GFS
Sbjct: 654 ---PFKPKIKSKRDANNFDSDFTKE-------EPVLTPSDPAVVR----AINQDEFRGFS 699
Query: 545 YV 546
++
Sbjct: 700 FI 701
>SPBC106.10 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 512
Score = 175 bits (443), Expect = 2e-43
Identities = 135/417 (32%), Positives = 199/417 (47%), Gaps = 50/417 (11%)
Query: 88 LVPPDSGESKQSQTKEPARRRSSLYNKFVVNPAQHTIRLSLNAQGDSDKETRDVLSVSSV 147
L+P ES + + + +R S + + ++H R S G D+ R V VS +
Sbjct: 121 LIPSPLPESASRSSSQSSHQRHSRDGRGELG-SEHGERRSA-MDGLRDRHIRKV-RVSQL 177
Query: 148 EETRQLRASSFSKTGAPRV-LDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEI 206
+ ++ R T R + DF ++ LG G++G YA+K L+K +I
Sbjct: 178 LDLQRRRIRPADHTTKDRYGIQDFNFLQTLGTGSFGRVHLVQSNHNRLYYAIKVLEKKKI 237
Query: 207 LISEDSIEKDANTTVEKRIERTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGG 266
+ K+IE T ER ILS+++HP I L+ +F D L++V+ + GG
Sbjct: 238 VDM-------------KQIEHTCDERYILSRVQHPFITILWGTFQDAKNLFMVMDFAEGG 284
Query: 267 ELFYHLKEQGTLDEGTVAFYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFG 326
ELF L++ E FYAAE+ AL +LH IVYRDLKPEN LL+ GHL + DFG
Sbjct: 285 ELFSLLRKCHRFPEKVAKFYAAEVILALDYLHHNQIVYRDLKPENLLLDRFGHLKIVDFG 344
Query: 327 LSKKSVFDDAATPEEGENVNQLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLI 386
+K+ + T + GTP+Y APEI++ +PY + DW+SLG L+++ML
Sbjct: 345 FAKRVSTSNCCT------------LCGTPDYLAPEIISLKPYNKAADWWSLGILIFEMLA 392
Query: 387 GKPPFTGVNHKIILNKIKQEKTGARIPSYLSDGFKDYLGALLRKDPTKRWDVDKYWAQDG 446
G PPF N + I + K PSY S D L LL++D T R+ K + D
Sbjct: 393 GYPPFYSENPMKLYENILEGK--VNYPSYFSPASIDLLSHLLQRDITCRYGNLKDGSMD- 449
Query: 447 PXXXXXXXXXXXXXNYIGHFIFRKIIWKQLLSGDLQKISVGPILPIITDWELAENFD 503
I H FR I W ++L+ +KI V + PI + FD
Sbjct: 450 ---------------IIMHPWFRDISWDKILT---RKIEVPYVPPIQAGMGDSSQFD 488
>CE28760 [R] KOG0605 NDR and related serine/threonine kinases
Length = 467
Score = 175 bits (443), Expect = 2e-43
Identities = 110/312 (35%), Positives = 166/312 (52%), Gaps = 48/312 (15%)
Query: 110 SLYNKFVVNPAQHTIRLS-----LNAQGDSDKETRDVLSVSSVEETRQLRASSFSKTGAP 164
S Y+K V A+ RL ++A+G SD+E + + +ET LR T
Sbjct: 20 SYYSKRVTQCAERENRLKKLEEDISARGLSDEEKEEKRKIHHSKETDYLRLKRTRLT--- 76
Query: 165 RVLDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKR 224
++DF ++ +G GA+G YAMK L+K+E+ +EK+ V
Sbjct: 77 --VNDFESLKVIGRGAFGEVRLVQKHDTGHIYAMKILRKSEM------VEKEQTAHVR-- 126
Query: 225 IERTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVA 284
AER ILS+ + +VK++YSF D LYLV++++PGG++ L ++ TL E
Sbjct: 127 -----AERDILSEADCDWVVKMYYSFQDYSNLYLVMEFLPGGDMMTLLIKKDTLTEEATQ 181
Query: 285 FYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLS---KKSVFDD------ 335
FY AE + A++F+HS G ++RD+KP+N LL+ RGH+ L+DFGL KK D
Sbjct: 182 FYIAEAALAIQFIHSLGFIHRDIKPDNLLLDARGHVKLSDFGLCTGLKKFHRTDHYRNWP 241
Query: 336 -------AATPEEGENVNQ---------LYSIIGTPEYCAPEILAGEPYTQNCDWYSLGC 379
+ P E + + YS +GTP+Y APE+ YT++CDW+SLG
Sbjct: 242 STLPPDFISKPFESKRKAETWKRNRRAYAYSTVGTPDYIAPEVFQPNGYTKSCDWWSLGV 301
Query: 380 LVYDMLIGKPPF 391
++Y+MLIG PPF
Sbjct: 302 IMYEMLIGYPPF 313
>7295638 [T] KOG0603 Ribosomal protein S6 kinase
Length = 911
Score = 175 bits (443), Expect = 2e-43
Identities = 129/382 (33%), Positives = 185/382 (47%), Gaps = 66/382 (17%)
Query: 170 FVPIRCLGEGAYGXXXXXXXXX---XXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIE 226
F +R LGEG++G YAMK LKKA + + + R+
Sbjct: 199 FELLRVLGEGSFGKVFLVRKIIGKDAGTLYAMKVLKKATLKVKD-------------RVR 245
Query: 227 RTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFY 286
T ER IL+ + H IV+L Y+F KLYL+L ++ GG+LF L ++ E V FY
Sbjct: 246 ST-NERKILADVGHAFIVRLHYAFQTPGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFY 304
Query: 287 AAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVN 346
AEL+ A+ LH+ GI+YRDLKPEN LL+E GH+ LTDFGLSK+ P +G +
Sbjct: 305 LAELALAMNHLHTLGIIYRDLKPENILLDEHGHIALTDFGLSKQ--------PLDG---S 353
Query: 347 QLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQE 406
+ YS GT EY APEI+ + + DW+S G L+Y+ML G PF G + +N+I +
Sbjct: 354 KTYSFCGTVEYMAPEIVNRKGHDFAADWWSFGVLMYEMLTGNLPFHGQTRQETMNQILRS 413
Query: 407 KTGARIPSYLSDGFKDYLGALLRKDPTKRWDVDKYWAQDGPXXXXXXXXXXXXXNYIGHF 466
K G +P LS + L AL +++P R D H
Sbjct: 414 KLG--MPENLSPEAQSLLRALFKRNPQNRLGAGAQGILD----------------IKAHC 455
Query: 467 IFRKIIWKQLLSGDLQKISVGPILPIITDWELAENFDTEFTEKRLDTSIYDNGIEINNPR 526
F I W +L ++ P +P ++ + A FD E+T K +PR
Sbjct: 456 FFATIDWVRLERKQVRP----PFIPAVSR-DDAFYFDVEYTSK--------------SPR 496
Query: 527 ATKESAFAGST-DYFKGFSYVA 547
+ + S + F+GFS+VA
Sbjct: 497 DSPGGPISASAHEIFRGFSFVA 518
Score = 97.8 bits (242), Expect = 4e-20
Identities = 74/258 (28%), Positives = 112/258 (42%), Gaps = 36/258 (13%)
Query: 162 GAPRVLDDFVP---------IRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDS 212
GAPR L +P ++ LG G + YA+K ++KA + + S
Sbjct: 551 GAPRTLPGVLPGNFHAEYNLLQELGRGTFSVCRLCEHRASKKHYAVKVIEKAAVAAASTS 610
Query: 213 IEKDANTTVEKRIERTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHL 272
D VE +L HPNIV L+ + D YLV++ + GGEL +
Sbjct: 611 TSADCWEEVE----------IMLRYGNHPNIVTLYSVYEDAGSAYLVMELLKGGELLDRI 660
Query: 273 KEQGTLDEGTVAFYAAELSCALKFLHSKGIVYRDLKPENCLLNERGH----LVLTDFGLS 328
G + E + ++ A+ +LH G+V+RDLKP N + L L D G +
Sbjct: 661 LAVGQMCESEASAVLRTIASAVAYLHEHGVVHRDLKPSNMIYASMRQTPETLKLCDLGFA 720
Query: 329 KKSVFDDAATPEEGENVNQLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGK 388
K+ D+ L + T + APE+L + Y CD +SLG L+Y ML G+
Sbjct: 721 KQLRADNGL----------LMTPCYTANFVAPEVLKRQGYDLACDIWSLGVLLYIMLSGR 770
Query: 389 PPFTGV---NHKIILNKI 403
PF + +IL +I
Sbjct: 771 TPFASTPNDSPDVILKRI 788
>CE04603 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 371
Score = 173 bits (439), Expect = 5e-43
Identities = 105/331 (31%), Positives = 171/331 (50%), Gaps = 47/331 (14%)
Query: 120 AQHTIRLSLNAQGDSD-----KETRDVLSVSSVEETRQLRASSFSKTGAPRVLDDFVPIR 174
A T + N++G++ +ET LS++ E SFS + R++
Sbjct: 22 ASFTFDTNNNSRGNNQVNELAEETHMKLSITPTRE-------SFSLSQLERIIT------ 68
Query: 175 CLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIERTFAERTI 234
+G+G +G YA+K L ++ ++ + E+ +
Sbjct: 69 -IGKGTFGRVELARDKITGAHYALKVLNIRRVVDM-------------RQTQHVHNEKRV 114
Query: 235 LSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAAELSCAL 294
L QL+HP IVK++ S D++ LY++++++PGGE+F +L+ + FYA+E+ CAL
Sbjct: 115 LLQLKHPFIVKMYASEKDSNHLYMIMEFVPGGEMFSYLRASRSFSNSMARFYASEIVCAL 174
Query: 295 KFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVNQLYSIIGT 354
+++HS GIVYRDLKPEN +L++ GH+ + DFG +K E ++ Y+I GT
Sbjct: 175 EYIHSLGIVYRDLKPENLMLSKEGHIKMADFGFAK-------------ELRDRTYTICGT 221
Query: 355 PEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQEKTGARIPS 414
P+Y APE LA + + DW++LG L+Y+M++GKPPF G I + I + K + P
Sbjct: 222 PDYLAPESLARTGHNKGVDWWALGILIYEMMVGKPPFRGKTTSEIYDAIIEHK--LKFPR 279
Query: 415 YLSDGFKDYLGALLRKDPTKRWDVDKYWAQD 445
+ KD + LL D T+R K QD
Sbjct: 280 SFNLAAKDLVKKLLEVDRTQRIGCMKNGTQD 310
>At3g17850 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1263
Score = 172 bits (436), Expect = 1e-42
Identities = 114/330 (34%), Positives = 166/330 (49%), Gaps = 43/330 (13%)
Query: 135 DKETRDVLSVSSVEET-------RQLRASSFSKTGAPRVLDDFVPIRCLGEGAYGXXXXX 187
D E D+LS E+ R LR S + DDF I+ + GA+G
Sbjct: 849 DDEKVDLLSTVIDEDAPLEDDVVRSLRTSPVHPRDRTSI-DDFEIIKPISRGAFGRVFLA 907
Query: 188 XXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIERTFAERTILSQLEHPNIVKLF 247
+A+K LKKA D I K+A +E AER IL + +P +V+ F
Sbjct: 908 KKRTTGDLFAIKVLKKA------DMIRKNA-------VESILAERDILINVRNPFVVRFF 954
Query: 248 YSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAAELSCALKFLHSKGIVYRDL 307
YSF LYLV++Y+ GG+L+ L+ G L+E V Y AE+ AL++LHS+G+V+RDL
Sbjct: 955 YSFTCRDNLYLVMEYLNGGDLYSLLRNLGCLEEDIVRVYIAEVVLALEYLHSEGVVHRDL 1014
Query: 308 KPENCLLNERGHLVLTDFGLSKKSVF---DDAATP------------------EEGENVN 346
KP+N L+ GH+ LTDFGLSK + DD A P EE
Sbjct: 1015 KPDNLLIAHDGHIKLTDFGLSKVGLINSTDDLAGPAVSGTSLLDEEESRLAASEEQLERR 1074
Query: 347 QLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQE 406
+ S +GTP+Y APEIL G + DW+S+G +++++++G PPF + + I + I
Sbjct: 1075 KKRSAVGTPDYLAPEILLGTGHGATADWWSVGIILFELIVGIPPFNAEHPQQIFDNILNR 1134
Query: 407 K-TGARIPSYLSDGFKDYLGALLRKDPTKR 435
K +P +S D + L +DP +R
Sbjct: 1135 KIPWPHVPEEMSAEAHDIIDRFLTEDPHQR 1164
>Hs5453972 [T] KOG0694 Serine/threonine protein kinase
Length = 682
Score = 171 bits (434), Expect = 2e-42
Identities = 118/383 (30%), Positives = 178/383 (45%), Gaps = 58/383 (15%)
Query: 167 LDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIE 226
+D+F IR LG+G++G YA+K LKK IL+ +D +E
Sbjct: 351 IDNFEFIRVLGKGSFGKVMLARVKETGDLYAVKVLKKDVILLDDD-------------VE 397
Query: 227 RTFAERTILSQLE-HPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAF 285
T E+ ILS HP + +LF F +L+ V++++ GG+L +H+++ DE F
Sbjct: 398 CTMTEKRILSLARNHPFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARF 457
Query: 286 YAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENV 345
YAAE+ AL FLH KGI+YRDLK +N LL+ GH L DFG+ K+ + + T
Sbjct: 458 YAAEIISALMFLHDKGIIYRDLKLDNVLLDHEGHCKLADFGMCKEGICNGVTTA------ 511
Query: 346 NQLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQ 405
+ GTP+Y APEIL Y DW+++G L+Y+ML G PF N + I
Sbjct: 512 ----TFCGTPDYIAPEILQEMLYGPAVDWWAMGVLLYEMLCGHAPFEAENEDDLFEAILN 567
Query: 406 EKTGARIPSYLSDGFKDYLGALLRKDPTKRWDVDKYWAQDGPXXXXXXXXXXXXXNYIGH 465
++ P++L + L + + K+PT R + H
Sbjct: 568 DE--VVYPTWLHEDATGILKSFMTKNPTMR---------------LGSLTQGGEHAILRH 610
Query: 466 FIFRKIIWKQLLSGDLQKISVGPILPIITDWELAENFDTEF-TEKRLDTSIYDNGIEINN 524
F++I W QL ++ P P I E NFD +F E+ + T I + + + N
Sbjct: 611 PFFKEIDWAQLNHRQIEP----PFRPRIKSREDVSNFDPDFIKEEPVLTPIDEGHLPMIN 666
Query: 525 PRATKESAFAGSTDYFKGFSYVA 547
D F+ FSYV+
Sbjct: 667 ------------QDEFRNFSYVS 677
>At1g48490 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1244
Score = 171 bits (434), Expect = 2e-42
Identities = 103/285 (36%), Positives = 155/285 (54%), Gaps = 29/285 (10%)
Query: 167 LDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIE 226
+DDF ++ + GA+G +A+K L+KA D I K+A +E
Sbjct: 825 IDDFEVMKSISRGAFGHVILARKNTTGDLFAIKVLRKA------DMIRKNA-------VE 871
Query: 227 RTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFY 286
AER IL +P +V+ FYSF + LYLV++Y+ GG+ + L++ G LDE Y
Sbjct: 872 SILAERDILINARNPFVVRFFYSFTCSENLYLVMEYLNGGDFYSMLRKIGCLDEANARVY 931
Query: 287 AAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVF---DDAATP---- 339
AE+ AL++LHS+G+V+RDLKP+N L+ GH+ LTDFGLSK + DD + P
Sbjct: 932 IAEVVLALEYLHSEGVVHRDLKPDNLLIAHDGHVKLTDFGLSKVGLINNTDDLSGPVSSA 991
Query: 340 -----EEGENVNQL---YSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPF 391
EE + L S +GTP+Y APEIL G + DW+S+G ++Y+ L+G PPF
Sbjct: 992 TSLLVEEKPKLPTLDHKRSAVGTPDYLAPEILLGTGHGATADWWSVGIILYEFLVGIPPF 1051
Query: 392 TGVN-HKIILNKIKQEKTGARIPSYLSDGFKDYLGALLRKDPTKR 435
+ +I N + + +P +S +D + LL +DP +R
Sbjct: 1052 NADHPQQIFDNILNRNIQWPPVPEDMSHEARDLIDRLLTEDPHQR 1096
>CE02586 [T] KOG0696 Serine/threonine protein kinase
Length = 861
Score = 170 bits (431), Expect = 5e-42
Identities = 107/339 (31%), Positives = 167/339 (48%), Gaps = 43/339 (12%)
Query: 169 DFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIERT 228
DF + LG+G++G +A+K LKK +++I +D +E T
Sbjct: 412 DFNFLTVLGKGSFGKVLLGEQKTTKELFAIKVLKK-DVIIQDDDVEC------------T 458
Query: 229 FAERTILSQLEHPN-IVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYA 287
E+ +L+ E P+ +V L F +LY V++++ GG+L Y +++ G E FYA
Sbjct: 459 MTEKRVLALPEKPSFLVALHSCFQTMDRLYFVMEFVNGGDLMYQIQQVGKFKEPVAVFYA 518
Query: 288 AELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVNQ 347
AE++ L FLHSKGI+YRDLK +N +L GH+ +TDFG+ K+++F DA T
Sbjct: 519 AEIAVGLFFLHSKGIIYRDLKLDNVMLERDGHIKITDFGMCKENIFGDATTK-------- 570
Query: 348 LYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQEK 407
+ GTP+Y APEI+ +PY ++ DW++ G L+++ML G+PPF G + + I +
Sbjct: 571 --TFCGTPDYIAPEIILYQPYGKSVDWWAYGVLLFEMLAGQPPFDGEDEDELFTAITEHN 628
Query: 408 TGARIPSYLSDGFKDYLGALLRKDPTKRWDVDKYWAQDGPXXXXXXXXXXXXXNYIGHFI 467
P LS ALL K+P+KR + H
Sbjct: 629 VS--YPKSLSKEAVSLCKALLIKNPSKR-------------LGCTGDDESASRDIKEHPF 673
Query: 468 FRKIIWKQLLSGDLQKISVGPILPIITDWELAENFDTEF 506
FR+I W ++ + +Q P P + ENFD F
Sbjct: 674 FRRIDWFKIETRQIQP----PFKPKLKTDRSTENFDHSF 708
>YKL166c [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 398
Score = 169 bits (429), Expect = 8e-42
Identities = 105/322 (32%), Positives = 166/322 (50%), Gaps = 46/322 (14%)
Query: 158 FSKTGAPRVLDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDA 217
+ T L DF +R LG G++G YA+K LKK I+
Sbjct: 76 YRDTSGKYSLSDFQILRTLGTGSFGRVHLIRSNHNGRFYALKTLKKHTIVKL-------- 127
Query: 218 NTTVEKRIERTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGT 277
K++E T ER +LS + HP I++++ +F D+ ++++V+ YI GGELF L++
Sbjct: 128 -----KQVEHTNDERRMLSIVSHPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQR 182
Query: 278 LDEGTVAFYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAA 337
FYAAE+ AL++LHSK I+YRDLKPEN LL++ GH+ +TDFG +K
Sbjct: 183 FPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAK-------Y 235
Query: 338 TPEEGENVNQLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVN-H 396
P+ Y++ GTP+Y APE+++ +PY ++ DW+S G L+Y+ML G PF N
Sbjct: 236 VPD------VTYTLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYNSNTM 289
Query: 397 KIILNKIKQEKTGARIPSYLSDGFKDYLGALLRKDPTKRWDVDKYWAQDGPXXXXXXXXX 456
K N + E + P + +D L L+ +D ++R + ++D
Sbjct: 290 KTYENILNAE---LKFPPFFHPDAQDLLKKLITRDLSERLGNLQNGSED----------- 335
Query: 457 XXXXNYIGHFIFRKIIWKQLLS 478
H F ++IW++LL+
Sbjct: 336 -----VKNHPWFNEVIWEKLLA 352
>Hs4885563 [T] KOG0694 Serine/threonine protein kinase
Length = 737
Score = 169 bits (427), Expect = 1e-41
Identities = 134/481 (27%), Positives = 220/481 (44%), Gaps = 67/481 (13%)
Query: 71 EALISDTEEQAEMMSGFLVP-PDSGESKQSQTKEPARRRSSLYNKFVVNPAQHTIR--LS 127
+ + + + + ++++G P P SG S + + + S + + ++ IR LS
Sbjct: 311 DKITNSGQRRKKLIAGAESPQPASGSSPSEEDRSKSAPTSPCDQE--IKELENNIRKALS 368
Query: 128 LNAQGDSDKETRDVLS-VSSVEETRQLRASSFSKTGAPRVLDDFVPIRCLGEGAYGXXXX 186
+ +G+ + + S E ++R + G LD+F I+ LG+G++G
Sbjct: 369 FDNRGEEHRAASSPDGQLMSPGENGEVRQGQAKRLG----LDEFNFIKVLGKGSFGKVML 424
Query: 187 XXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIERTFAERTILSQLEHPNIVKL 246
YA+K LKK ++++ +D ++ T EKRI + +HP + +L
Sbjct: 425 AELKGKDEVYAVKVLKK-DVILQDDDVDC---TMTEKRI--------LALARKHPYLTQL 472
Query: 247 FYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAAELSCALKFLHSKGIVYRD 306
+ F +L+ V++Y+ GG+L + ++ DE FYAAE++ AL FLH G++YRD
Sbjct: 473 YCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTSALMFLHQHGVIYRD 532
Query: 307 LKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVNQLYSIIGTPEYCAPEILAGE 366
LK +N LL+ GH L DFG+ K+ + + T + GTP+Y APEIL
Sbjct: 533 LKLDNILLDAEGHCKLADFGMCKEGILNGVTTT----------TFCGTPDYIAPEILQEL 582
Query: 367 PYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQEKTGARIPSYLSDGFKDYLGA 426
Y + DW++LG L+Y+M+ G+PPF N + I + P +LS L A
Sbjct: 583 EYGPSVDWWALGVLMYEMMAGQPPFEADNEDDLFESILHD--DVLYPVWLSKEAVSILKA 640
Query: 427 LLRKDPTKRWDVDKYWAQDGPXXXXXXXXXXXXXNYIGHFIFRKIIWKQLLSGDLQKISV 486
+ K+P KR + +Q+G H F++I W L QK
Sbjct: 641 FMTKNPHKR--LGCVASQNGEDAIKQ------------HPFFKEIDWVLL----EQKKIK 682
Query: 487 GPILPIITDWELAENFDTEFTEKRLDTSIYDNGI--EINNPRATKESAFAGSTDYFKGFS 544
P P I NFD +FT + ++ D I +IN + FKGFS
Sbjct: 683 PPFKPRIKTKRDVNNFDQDFTREEPVLTLVDEAIVKQINQ-------------EEFKGFS 729
Query: 545 Y 545
Y
Sbjct: 730 Y 730
>Hs20535816 [T] KOG0695 Serine/threonine protein kinase
Length = 592
Score = 169 bits (427), Expect = 1e-41
Identities = 129/387 (33%), Positives = 183/387 (46%), Gaps = 66/387 (17%)
Query: 167 LDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIE 226
L DF IR +G G+Y YAMK +KK + ED I+
Sbjct: 249 LQDFDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKELVHDDED-------------ID 295
Query: 227 RTFAERTILSQLE-HPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAF 285
E+ + Q +P +V L F +L+LV++Y+ GG+L +H++ Q L E F
Sbjct: 296 WVQTEKHVFEQASSNPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARF 355
Query: 286 YAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENV 345
YAAE+ AL FLH +GI+YRDLK +N LL+ GH+ LTD+G+ K+ + T
Sbjct: 356 YAAEICIALNFLHERGIIYRDLKLDNVLLDADGHIKLTDYGMCKEGLGPGDTTS------ 409
Query: 346 NQLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPF------TGVNHKII 399
+ GTP Y APEIL GE Y + DW++LG L+++M+ G+ PF +N +
Sbjct: 410 ----TFCGTPNYIAPEILRGEEYGFSVDWWALGVLMFEMMAGRSPFDIITDNPDMNTEDY 465
Query: 400 LNKIKQEKTGARIPSYLSDGFKDYLGALLRKDPTKRWDVDKYWAQDGPXXXXXXXXXXXX 459
L ++ EK RIP +LS L L KDP +R Q G
Sbjct: 466 LFQVILEKP-IRIPRFLSVKASHVLKGFLNKDPKERLGCR---PQTG------------F 509
Query: 460 XNYIGHFIFRKIIWKQLLSGDLQKISVGPILPIITDWELAENFDTEFTE----------- 508
+ H FR I W L +K ++ P P ITD +NFDT+FT
Sbjct: 510 SDIKSHAFFRSIDWDLL----EKKQALPPFQPQITDDYGLDNFDTQFTSEPVQLTPDDED 565
Query: 509 --KRLDTSIYDNGIEINNP--RATKES 531
KR+D S ++ G E NP +T+ES
Sbjct: 566 AIKRIDQSEFE-GFEYINPLLLSTEES 591
>Hs10864650 [T] KOG0695 Serine/threonine protein kinase
Length = 592
Score = 169 bits (427), Expect = 1e-41
Identities = 129/387 (33%), Positives = 183/387 (46%), Gaps = 66/387 (17%)
Query: 167 LDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIE 226
L DF IR +G G+Y YAMK +KK + ED I+
Sbjct: 249 LQDFDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKELVHDDED-------------ID 295
Query: 227 RTFAERTILSQLE-HPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAF 285
E+ + Q +P +V L F +L+LV++Y+ GG+L +H++ Q L E F
Sbjct: 296 WVQTEKHVFEQASSNPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARF 355
Query: 286 YAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENV 345
YAAE+ AL FLH +GI+YRDLK +N LL+ GH+ LTD+G+ K+ + T
Sbjct: 356 YAAEICIALNFLHERGIIYRDLKLDNVLLDADGHIKLTDYGMCKEGLGPGDTTS------ 409
Query: 346 NQLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPF------TGVNHKII 399
+ GTP Y APEIL GE Y + DW++LG L+++M+ G+ PF +N +
Sbjct: 410 ----TFCGTPNYIAPEILRGEEYGFSVDWWALGVLMFEMMAGRSPFDIITDNPDMNTEDY 465
Query: 400 LNKIKQEKTGARIPSYLSDGFKDYLGALLRKDPTKRWDVDKYWAQDGPXXXXXXXXXXXX 459
L ++ EK RIP +LS L L KDP +R Q G
Sbjct: 466 LFQVILEKP-IRIPRFLSVKASHVLKGFLNKDPKERLGCR---PQTG------------F 509
Query: 460 XNYIGHFIFRKIIWKQLLSGDLQKISVGPILPIITDWELAENFDTEFTE----------- 508
+ H FR I W L +K ++ P P ITD +NFDT+FT
Sbjct: 510 SDIKSHAFFRSIDWDLL----EKKQALPPFQPQITDDYGLDNFDTQFTSEPVQLTPDDED 565
Query: 509 --KRLDTSIYDNGIEINNP--RATKES 531
KR+D S ++ G E NP +T+ES
Sbjct: 566 AIKRIDQSEFE-GFEYINPLLLSTEES 591
>CE27166 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 270
Score = 168 bits (426), Expect = 2e-41
Identities = 85/223 (38%), Positives = 134/223 (59%), Gaps = 15/223 (6%)
Query: 223 KRIERTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGT 282
++ + E+ +L QL+HP IVK++ S D++ LY++++++PGGE+F +L+ +
Sbjct: 2 RQTQHVHNEKRVLLQLKHPFIVKMYASEKDSNHLYMIMEFVPGGEMFSYLRASRSFSNSM 61
Query: 283 VAFYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEG 342
FYA+E+ CAL+++HS GIVYRDLKPEN +L++ GH+ + DFG +K
Sbjct: 62 ARFYASEIVCALEYIHSLGIVYRDLKPENLMLSKEGHIKMADFGFAK------------- 108
Query: 343 ENVNQLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNK 402
E ++ Y+I GTP+Y APE LA + + DW++LG L+Y+M++GKPPF G I +
Sbjct: 109 ELRDRTYTICGTPDYLAPESLARTGHNKGVDWWALGILIYEMMVGKPPFRGKTTSEIYDA 168
Query: 403 IKQEKTGARIPSYLSDGFKDYLGALLRKDPTKRWDVDKYWAQD 445
I + K + P + KD + LL D T+R K QD
Sbjct: 169 IIEHK--LKFPRSFNLAAKDLVKKLLEVDRTQRIGCMKNGTQD 209
>At3g23310 [R] KOG0605 NDR and related serine/threonine kinases
Length = 568
Score = 168 bits (426), Expect = 2e-41
Identities = 123/395 (31%), Positives = 189/395 (47%), Gaps = 70/395 (17%)
Query: 70 EEALISDTEEQAEMMSGFLVPPDSGESKQSQTKEPAR-RRSSLYNKFVVNPAQHTIRLSL 128
EEA+ + T+++A ++ ++ KQ Q+++ + RR L NK L
Sbjct: 40 EEAVSNVTKQKAAAAKQYI---ENHYKKQVQSQQQRKERRDMLENK-------------L 83
Query: 129 NAQGDSDKETRDVLSVSSVEETRQLRASSFSKTGAPRVLDDFVPIRCLGEGAYGXXXXXX 188
A S++E +++L +ET +R K G DDF P+ +G+GA+G
Sbjct: 84 AAAEVSEEEQKNLLKDLEKKETEYMRRQRH-KMGT----DDFEPLTMIGKGAFGEVRICR 138
Query: 189 XXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIERTFAERTILSQLEHPNIVKLFY 248
YAMK+LKK+E+L ++E AER +L++++ IVKL+
Sbjct: 139 EKTTGNVYAMKKLKKSEMLR-------------RGQVEHVKAERNLLAEVDSNCIVKLYC 185
Query: 249 SFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAAELSCALKFLHSKGIVYRDLK 308
SF D LYL+++Y+PGG++ L + TL E FY E A++ +H ++RD+K
Sbjct: 186 SFQDEEYLYLIMEYLPGGDMMTLLMRKDTLTEDEARFYVGETVLAIESIHKHNYIHRDIK 245
Query: 309 PENCLLNERGHLVLTDFGLSKK---SVFDD----------AATPEEGENV---------N 346
P+N LL+ GH+ L+DFGL K S+ + A +G V
Sbjct: 246 PDNLLLDRSGHMKLSDFGLCKPLDCSILQEKDFVVAHNLSGALQSDGRPVAPRRTRSQME 305
Query: 347 QL-----------YSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVN 395
QL YS +GTP+Y APE+L + Y CDW+SLG ++Y+ML+G PPF
Sbjct: 306 QLQNWQRNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGFPPFYSDE 365
Query: 396 HKIILNKIKQEKTGARIPS--YLSDGFKDYLGALL 428
KI K + P LS KD + LL
Sbjct: 366 PMTTCRKIVNWKNYLKFPDEVRLSPEAKDLICRLL 400
>CE18699 [T] KOG0694 Serine/threonine protein kinase
Length = 1018
Score = 168 bits (425), Expect = 2e-41
Identities = 117/354 (33%), Positives = 174/354 (49%), Gaps = 45/354 (12%)
Query: 159 SKTGAPRVLDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDAN 218
S GAP ++ F I LG G +G YA+K LKK +IL D +E +
Sbjct: 679 SSDGAPLTVEQFRLISVLGRGHFGKVILSQHNPTSNYYALKVLKKGDIL-GRDEVE---S 734
Query: 219 TTVEKRIERTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTL 278
VEKRI + S+ HP +V L F N ++ ++Y GG+L H+ +
Sbjct: 735 LMVEKRIFE------VSSRARHPFLVNLNGCFQTNEHVFFCMEYSMGGDLMRHIHDD-VF 787
Query: 279 DEGTVAFYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSV--FDDA 336
DE FYAA + L FLH I+YRD+K +N LL+ G++ + DFGL K+++ FD
Sbjct: 788 DEVRGCFYAACVVLGLDFLHKHNIIYRDIKLDNLLLDREGYVKIADFGLCKENMGPFDKT 847
Query: 337 ATPEEGENVNQLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNH 396
+T GTPE+ APE+L+ YT+ DW+ LG L+++ML+G+PPF+G +
Sbjct: 848 ST------------FCGTPEFLAPEVLSDSSYTRAIDWWGLGVLIFEMLVGEPPFSGDDE 895
Query: 397 KIILNKIKQEKTGARIPSYLSDGFKDYLGALLRKDPTKRWDVDKYWAQDGPXXXXXXXXX 456
+ I + I E R P YLS + LLRK P KR + A+D
Sbjct: 896 EEIFDSIISE--DVRYPRYLSVESIAIMRRLLRKVPEKRLGYGERDAED----------- 942
Query: 457 XXXXNYIGHFIFRKIIWKQLLSGDLQKISVGPILPIITDWELAENFDTEFTEKR 510
+ H + W +LL+ +++ P P I + E NFD EFT+++
Sbjct: 943 IKIQRFFRHISWE---WDKLLNREIRP----PFQPQIRNPEDVSNFDLEFTQEK 989
>7302861 [T] KOG0696 Serine/threonine protein kinase
Length = 700
Score = 168 bits (425), Expect = 2e-41
Identities = 107/355 (30%), Positives = 172/355 (48%), Gaps = 44/355 (12%)
Query: 169 DFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIERT 228
DF ++ +G+G++G YA+K L+K +++I D +E N EK+I
Sbjct: 370 DFNFVKVIGKGSFGKVLLAERRGTDELYAVKVLRK-DVIIQTDDMELPMN---EKKI--- 422
Query: 229 FAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAA 288
+ P +V + F +L+ V++Y GG+L YH+++ G E FYA
Sbjct: 423 -----LALSGRPPFLVSMHSCFQTMDRLFFVMEYCKGGDLMYHMQQYGRFKESVAIFYAV 477
Query: 289 ELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVNQL 348
E++ AL FLH + I+YRDLK +N LL+ GH+ L DFGLSK+ V + T
Sbjct: 478 EVAIALFFLHERDIIYRDLKLDNILLDGEGHVKLVDFGLSKEGVTERQTT---------- 527
Query: 349 YSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQEKT 408
+ GTP Y APEI++ +PY+ DW+S G L+++ + G+ PF G + + IK +K
Sbjct: 528 RTFCGTPNYMAPEIVSYDPYSIAADWWSFGVLLFEFMAGQAPFEGDDETTVFRNIKDKK- 586
Query: 409 GARIPSYLSDGFKDYLGALLRKDPTKRWDVDKYWAQDGPXXXXXXXXXXXXXNYIGHFIF 468
A P + S D + + L K P R +Y Q+ H F
Sbjct: 587 -AVFPKHFSVEAMDIITSFLTKKPNNRLGAGRYARQE----------------ITTHPFF 629
Query: 469 RKIIWKQLLSGDLQKISVGPILPIITDWELAENFDTEFTEKRLDTSIYDNGIEIN 523
R + W + + +++ PI P+I + NFD FT+++ D + D +N
Sbjct: 630 RNVDWDKAEACEMEP----PIKPMIKHRKDISNFDDAFTKEKTDLTPTDKLFMMN 680
>SPAC22E12.14c [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 646
Score = 167 bits (424), Expect = 3e-41
Identities = 129/386 (33%), Positives = 176/386 (45%), Gaps = 60/386 (15%)
Query: 168 DDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIER 227
DDFVP++ +G+G +G YAMK L K I+ K +
Sbjct: 264 DDFVPLKLIGKGTFGQVYLVRKKDTERVYAMKVLSKKVIVR-------------RKEVAH 310
Query: 228 TFAERTILSQL---EHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVA 284
T ER IL Q + P IV L +SF LYLV Y+ GGELF+HL++ E
Sbjct: 311 TVGERDILVQTSAADSPFIVALRFSFQTPKDLYLVTDYMAGGELFWHLQKSVRFPEERAK 370
Query: 285 FYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGEN 344
FY AEL AL+ LH +GIVYRDLKPEN LL+ +GH+ L DFGLSK ++ T
Sbjct: 371 FYIAELLLALQALHKRGIVYRDLKPENILLDVQGHIALCDFGLSKANLSVGTTT------ 424
Query: 345 VNQLYSIIGTPEYCAPEILAGEP-YTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKI 403
+ GT +Y APE++ E Y D++SLG L+Y+M G PF N + + I
Sbjct: 425 ----RTFCGTTDYLAPEVILDEAGYDMMVDFWSLGVLLYEMTCGWSPFYADNTQQLYKNI 480
Query: 404 KQEKTGARIP-SYLSDGFKDYLGALLRKDPTKRWDVDKYWAQDGPXXXXXXXXXXXXXNY 462
K R P LS +D + LL ++P R
Sbjct: 481 VFGK--VRFPRGLLSVEARDLIKLLLNRNPKHR-----------------LGAHGDVEEV 521
Query: 463 IGHFIFRKIIWKQLLSGDLQKISVGPILPIITDWELAENFDTEFTEKRLDTSIYDNGIEI 522
+ H F I WK+L + ++ P PI+ NFD EFT K +D +
Sbjct: 522 MKHPFFDGIDWKKLAAKEISP----PFKPIVEGEIDVSNFDVEFTNKAIDR-------DF 570
Query: 523 NNPRATKESAFAGST--DYFKGFSYV 546
++ SA ST + FKGF+Y+
Sbjct: 571 SSTDEMSTSAPLSSTVQNGFKGFTYI 596
>Hs4506071 [T] KOG0695 Serine/threonine protein kinase
Length = 587
Score = 167 bits (422), Expect = 5e-41
Identities = 124/397 (31%), Positives = 182/397 (45%), Gaps = 56/397 (14%)
Query: 148 EETRQLRASSFSKTGAPRVLDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEIL 207
EE + K + L DF +R +G G+Y YAMK +KK +
Sbjct: 223 EEKEAMNTRESGKASSSLGLQDFDLLRVIGRGSYAKVLLVRLKKTDRIYAMKVVKKELVN 282
Query: 208 ISEDSIEKDANTTVEKRIERTFAERTILSQLE-HPNIVKLFYSFHDNHKLYLVLQYIPGG 266
ED I+ E+ + Q HP +V L F +L+ V++Y+ GG
Sbjct: 283 DDED-------------IDWVQTEKHVFEQASNHPFLVGLHSCFQTESRLFFVIEYVNGG 329
Query: 267 ELFYHLKEQGTLDEGTVAFYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFG 326
+L +H++ Q L E FY+AE+S AL +LH +GI+YRDLK +N LL+ GH+ LTD+G
Sbjct: 330 DLMFHMQRQRKLPEEHARFYSAEISLALNYLHERGIIYRDLKLDNVLLDSEGHIKLTDYG 389
Query: 327 LSKKSVFDDAATPEEGENVNQLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLI 386
+ K+ + T + GTP Y APEIL GE Y + DW++LG L+++M+
Sbjct: 390 MCKEGLRPGDTTS----------TFCGTPNYIAPEILRGEDYGFSVDWWALGVLMFEMMA 439
Query: 387 GKPPFTGV--------NHKIILNKIKQEKTGARIPSYLSDGFKDYLGALLRKDPTKRWDV 438
G+ PF V N + L ++ EK RIP LS L + L KDP +R
Sbjct: 440 GRSPFDIVGSSDNPDQNTEDYLFQVILEKQ-IRIPRSLSVKAASVLKSFLNKDPKERLGC 498
Query: 439 DKYWAQDGPXXXXXXXXXXXXXNYIGHFIFRKIIWKQLLSGDLQKISVGPILPIITDWEL 498
Q G + GH FR + W + QK V P P I+
Sbjct: 499 H---PQTG------------FADIQGHPFFRNVDWDMM----EQKQVVPPFKPNISGEFG 539
Query: 499 AENFDTEFTEKRLDTSIYDNGIEINNPRATKESAFAG 535
+NFD++FT + + + D+ I R +S F G
Sbjct: 540 LDNFDSQFTNEPVQLTPDDDDI----VRKIDQSEFEG 572
>At1g45160 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1067
Score = 166 bits (421), Expect = 7e-41
Identities = 109/325 (33%), Positives = 166/325 (50%), Gaps = 45/325 (13%)
Query: 138 TRDVLSVSSVEETRQLRASSFSKTGAPRVL-------DDFVPIRCLGEGAYGXXXXXXXX 190
T D SV +++E+ + + + P++L DDF I+ + GA+G
Sbjct: 634 TADKSSVGNIKESEDVLEHA---SATPQLLLKDRISIDDFEIIKPISRGAFGKVFLARKR 690
Query: 191 XXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIERTFAERTILSQLEHPNIVKLFYSF 250
+A+K LKK +++ D IER ER IL + +P +V+ FYSF
Sbjct: 691 TTGDFFAIKVLKKLDMIRKND-------------IERILQERNILITVRYPFLVRFFYSF 737
Query: 251 HDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAAELSCALKFLHSKGIVYRDLKPE 310
LYLV++Y+ GG+L+ L++ G LDE Y AEL AL++LHS IV+RDLKP+
Sbjct: 738 TCRDNLYLVMEYLNGGDLYSLLQKVGCLDEEIARIYIAELVLALEYLHSLKIVHRDLKPD 797
Query: 311 NCLLNERGHLVLTDFGLSKKSVFDDA---------ATP----------EEGENVNQLYSI 351
N L+ GH+ LTDFGLSK + ++ +P +E E + +S
Sbjct: 798 NLLIAYNGHIKLTDFGLSKIGLINNTIDLSGHESDVSPRTNSHHFQKNQEEERIR--HSA 855
Query: 352 IGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVN-HKIILNKIKQEKTGA 410
+GTP+Y APEIL G + DW+S G +++++L G PPFT KI N + +
Sbjct: 856 VGTPDYLAPEILLGTEHGYAADWWSAGIVLFELLTGIPPFTASRPEKIFDNILNGKMPWP 915
Query: 411 RIPSYLSDGFKDYLGALLRKDPTKR 435
+P +S +D + LL +P KR
Sbjct: 916 DVPGEMSYEAQDLINRLLVHEPEKR 940
>7301734 [T] KOG0694 Serine/threonine protein kinase
Length = 739
Score = 166 bits (420), Expect = 9e-41
Identities = 136/484 (28%), Positives = 215/484 (44%), Gaps = 87/484 (17%)
Query: 76 DTEEQAEMMSGFLVPPDSGESKQSQTKEPARRRSSLYNKFVVNPAQHTIRLSLNAQGD-- 133
+T++ AE++S + PD + RRS N+ + SL A GD
Sbjct: 304 NTKQMAEILSSLGISPDKQQP----------RRSKYLNQ---QGGEDNYGASLGADGDGA 350
Query: 134 ------SDKETRDVLSVSSVEETRQLRASS---FSKTGAPRV------------LDDFVP 172
S + D L+ S+ T +SS + TG+ V L DF
Sbjct: 351 PGQSFRSCALSVDSLATSTTTMTSGYNSSSCMSLAVTGSGGVGATGETRPGKCSLLDFNF 410
Query: 173 IRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIERTFAER 232
I+ LG+G++G YA+K LKK I+ +D ++ T E+
Sbjct: 411 IKVLGKGSFGKVMLAEKKGTDEIYAIKVLKKDAIIQDDD-------------VDCTMTEK 457
Query: 233 TILS-QLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAAELS 291
IL+ HP + L F +L+ V++Y+ GG+L + +++ + AFYAAE++
Sbjct: 458 RILALAANHPFLTALHSCFQTPDRLFFVMEYVNGGDLMFQIQKARRFEASRAAFYAAEVT 517
Query: 292 CALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVNQLYSI 351
AL+FLH+ G++YRDLK +N LL++ GH L DFG+ K+ + + T +
Sbjct: 518 LALQFLHTHGVIYRDLKLDNILLDQEGHCKLADFGMCKEGIMNGMLTT----------TF 567
Query: 352 IGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQEKTGAR 411
GTP+Y APEIL + Y + DW++LG L+Y+M+ G+PPF N + + I +
Sbjct: 568 CGTPDYIAPEILKEQEYGASVDWWALGVLMYEMMAGQPPFEADNEDELFDSIMHD--DVL 625
Query: 412 IPSYLSDGFKDYLGALLRKDPTKRWDVDKYWAQDGPXXXXXXXXXXXXXNYIGHFIFRKI 471
P +LS L L K+P +R H F K+
Sbjct: 626 YPVWLSREAVSILKGFLTKNPEQR-----------------LGCTGDENEIRKHPFFAKL 668
Query: 472 IWKQLLSGDLQKISVGPILPIITDWELAENFDTEFTEKRLDTSIYDNGIEINNPRATKES 531
WK+L +++ P P + + A NFD EFT++ D + G E+ R +
Sbjct: 669 DWKELEKRNIKP----PFRPKMKNPRDANNFDAEFTKE--DPVLTPIGNEV--VRCINQD 720
Query: 532 AFAG 535
FAG
Sbjct: 721 EFAG 724
>At1g30640 [R] KOG0605 NDR and related serine/threonine kinases
Length = 562
Score = 165 bits (418), Expect = 1e-40
Identities = 111/376 (29%), Positives = 175/376 (46%), Gaps = 53/376 (14%)
Query: 90 PPDSGESKQSQTKEPARRRSSLYNKFVVNPAQHTIRLSLNAQGDSDKETRDVLSVSSVEE 149
P ++ + K + K+ + K + + L N D+D D + + E
Sbjct: 43 PSNATKQKVAAAKQYIENHYKIQKKSLQERKERRSILEQNL-ADADVTVEDKMDILKNFE 101
Query: 150 TRQLRASSFSKTGAPRVLDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILIS 209
+++ + +DDF + +G GA+G YAMK+LKK+E+L
Sbjct: 102 KKEMEYMRLQRQKMG--VDDFELLSIIGRGAFGEVRICKEKSTGSVYAMKKLKKSEMLR- 158
Query: 210 EDSIEKDANTTVEKRIERTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELF 269
++E AER +L++++ P IVKL YSF D+ LYL+++Y+PGG++
Sbjct: 159 ------------RGQVEHVKAERNVLAEVDSPFIVKLCYSFQDDEHLYLIMEYLPGGDMM 206
Query: 270 YHLKEQGTLDEGTVAFYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSK 329
L + TL E FY A+ A++ +H V+RD+KP+N L+ GH+ L+DFGLSK
Sbjct: 207 TLLMRKDTLREDETRFYVAQTILAIESIHKHNYVHRDIKPDNLLITRNGHIKLSDFGLSK 266
Query: 330 ----------KSVFDDAATPEEGEN--------------VNQL-----------YSIIGT 354
K+ D +T E+ QL +S +GT
Sbjct: 267 SLESKNFPDFKAELVDRSTKPAAEHDRLSKPPSAPRRTQQEQLLHWQQNRRTLAFSTVGT 326
Query: 355 PEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQEKTGARIP- 413
P+Y APE+L + Y CDW+SLG ++++ML+G PPF KI KT + P
Sbjct: 327 PDYIAPEVLLKKGYGMECDWWSLGAIMFEMLVGFPPFYSEEPLATCRKIVNWKTCLKFPD 386
Query: 414 -SYLSDGFKDYLGALL 428
+ LS KD + LL
Sbjct: 387 EAKLSIEVKDLIRRLL 402
>Hs13384594 [T] KOG0696 Serine/threonine protein kinase
Length = 697
Score = 165 bits (417), Expect = 2e-40
Identities = 109/342 (31%), Positives = 169/342 (48%), Gaps = 42/342 (12%)
Query: 167 LDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIE 226
+ DF + LG+G++G YA+K LKK ++++ +D ++ T VEKR+
Sbjct: 348 ISDFSFLMVLGKGSFGKVMLAERRGSDELYAIKILKK-DVIVQDDDVDC---TLVEKRVL 403
Query: 227 RTFAERTILSQLEHPN-IVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAF 285
P+ + +L +F +LY V++Y+ GG+L YH+++ G E AF
Sbjct: 404 ALGGR----GPGGRPHFLTQLHSTFQTPDRLYFVMEYVTGGDLMYHIQQLGKFKEPHAAF 459
Query: 286 YAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENV 345
YAAE++ L FLH++GI+YRDLK +N +L+ GH+ +TDFG+ K++VF T
Sbjct: 460 YAAEIAIGLFFLHNQGIIYRDLKLDNVMLDAEGHIKITDFGMCKENVFPGTTT------- 512
Query: 346 NQLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQ 405
+ GTP+Y APEI+A +PY ++ DW+S G L+Y+ML G+PPF G + + + I +
Sbjct: 513 ---RTFCGTPDYIAPEIIAYQPYGKSVDWWSFGVLLYEMLAGQPPFDGEDEEELFQAIME 569
Query: 406 EKTGARIPSYLSDGFKDYLGALLRKDPTKRWDVDKYWAQDGPXXXXXXXXXXXXXNYIGH 465
+ P LS L K P KR GP H
Sbjct: 570 QT--VTYPKSLSREAVAICKGFLTKHPGKR-------LGSGPDGEPTIR---------AH 611
Query: 466 FIFRKIIWKQLLSGDLQKISVGPILPIITDWELAENFDTEFT 507
FR I W++ L+++ + P ENFD FT
Sbjct: 612 GFFRWIDWER-----LERLEIPPPFRPRPCGRSGENFDKFFT 648
>7303111 [T] KOG0695 Serine/threonine protein kinase
Length = 690
Score = 165 bits (417), Expect = 2e-40
Identities = 126/389 (32%), Positives = 183/389 (46%), Gaps = 63/389 (16%)
Query: 167 LDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIE 226
L+DF IR +G G+Y YAMK +KKA L+++D T EK +
Sbjct: 258 LNDFELIRVIGRGSYAKVLMVELRRTRRIYAMKVIKKA--LVTDDEDIDWVQT--EKHVF 313
Query: 227 RTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFY 286
T + HP +V L F +L+ V++++ GG+L YH++ Q L E FY
Sbjct: 314 ETASN--------HPFLVGLHSCFQTPSRLFFVIEFVRGGDLMYHMQRQRRLPEEHARFY 365
Query: 287 AAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVN 346
AAE+S AL FLH KGI+YRDLK +N LL+ GH+ LTD+G+ K+ + T
Sbjct: 366 AAEISLALNFLHEKGIIYRDLKLDNVLLDHEGHIKLTDYGMCKEGIRPGDTTS------- 418
Query: 347 QLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPF--------TGVNHKI 398
+ GTP Y APEIL GE Y + DW++LG L+Y+ML G+ PF N +
Sbjct: 419 ---TFCGTPNYIAPEILRGEDYGFSVDWWALGVLLYEMLAGRSPFDLAGASENPDQNTED 475
Query: 399 ILNKIKQEKTGARIPSYLSDGFKDYLGALLRKDPTKRWDVDKYWAQDGPXXXXXXXXXXX 458
L ++ EKT RIP LS L L K+P R +
Sbjct: 476 YLFQVILEKT-IRIPRSLSVRAASVLKGFLNKNPADRLGCHR---------------ESA 519
Query: 459 XXNYIGHFIFRKIIWKQLLSGDLQKISVGPILP-IITDWELAENFDTEFTEKRLDTSIYD 517
+ + H F+ + W+ L +K P P + +D +LA NF EFT + + + D
Sbjct: 520 FMDIVSHPFFKNMDWELL----ERKQVTPPFKPRLDSDRDLA-NFPPEFTGEAVQLTPDD 574
Query: 518 NGIEINNPRATKESAFAGSTDYFKGFSYV 546
+ + N ++ F+GF YV
Sbjct: 575 DHVIDNIDQSE-----------FEGFEYV 592
>At2g20470 [R] KOG0605 NDR and related serine/threonine kinases
Length = 596
Score = 164 bits (415), Expect = 3e-40
Identities = 121/392 (30%), Positives = 188/392 (47%), Gaps = 66/392 (16%)
Query: 69 EEEALISDTEEQAEMMSGFLVPPDSGESKQSQTKEPARRRSSLYNKFVVNPAQHTIRLSL 128
+EEA+ + T+++ ++ + K Q ++ RRS L K
Sbjct: 43 DEEAVSNTTKQKVAAAKQYIENHYKEQMKILQERK--ERRSMLEQKL------------- 87
Query: 129 NAQGD-SDKETRDVLSVSSVEETRQLRASSFSKTGAPRVLDDFVPIRCLGEGAYGXXXXX 187
A D S+++ ++L +ET +R K G DF + +G+GA+G
Sbjct: 88 -ADADVSEEDQNNLLKFLEKKETEYMRLQRH-KLGVA----DFDLLTMIGKGAFGEVRVC 141
Query: 188 XXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIERTFAERTILSQLEHPNIVKLF 247
YAMK+LKKAE+L ++E AER +L++++ IVKL+
Sbjct: 142 REKTTGQVYAMKKLKKAEMLR-------------RGQVEHVRAERNLLAEVDSNYIVKLY 188
Query: 248 YSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAAELSCALKFLHSKGIVYRDL 307
SF D+ LYLV++Y+PGG++ L + TL E FY AE A++ +H ++RD+
Sbjct: 189 CSFQDDDHLYLVMEYLPGGDMMTLLMRKDTLTEEEAKFYVAETVLAIESIHRHNYIHRDI 248
Query: 308 KPENCLLNERGHLVLTDFGLSKK-----------SVFDDAATPEEGENV-------NQL- 348
KP+N LL+ GHL L+DFGL K S + +T +E + QL
Sbjct: 249 KPDNLLLDRYGHLRLSDFGLCKPLDCSAIGENDFSNNSNGSTEQEAGSTAPKRTQQEQLE 308
Query: 349 ----------YSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKI 398
YS +GTP+Y APE+L + Y CDW+SLG ++Y+ML+G PPF +
Sbjct: 309 HWQRNRRTLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFYSDDPMS 368
Query: 399 ILNKIKQEKTGARIP--SYLSDGFKDYLGALL 428
KI K+ + P + LS KD + +LL
Sbjct: 369 TCRKIVNWKSHLKFPEEAILSREAKDLINSLL 400
>Hs22068916 [T] KOG0696 Serine/threonine protein kinase
Length = 673
Score = 164 bits (414), Expect = 4e-40
Identities = 110/341 (32%), Positives = 165/341 (48%), Gaps = 45/341 (13%)
Query: 167 LDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIE 226
L DF + LG+G++G YA+K LKK +++I +D +E T VEKR+
Sbjct: 339 LTDFNFLMVLGKGSFGKVMLSERKGTDELYAVKILKK-DVVIQDDDVEC---TMVEKRVL 394
Query: 227 RTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFY 286
+ L+QL F +LY V++Y+ GG+L YH+++ G E FY
Sbjct: 395 ALPGKPPFLTQLHS--------CFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFY 446
Query: 287 AAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVN 346
AAE++ L FL SKGI+YRDLK +N +L+ GH+ + DFG+ K++++D T
Sbjct: 447 AAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTK------- 499
Query: 347 QLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQE 406
+ GTP+Y APEI+A +PY ++ DW++ G L+Y+ML G+ PF G + + I +
Sbjct: 500 ---TFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEH 556
Query: 407 KTGARIPSYLSDGFKDYLGALLRKDPTKRWDVDKYWAQDGPXXXXXXXXXXXXXNYIGHF 466
P +S L+ K P KR +D H
Sbjct: 557 NVA--YPKSMSKEAVAICKGLMTKHPGKRLGCGPEGERD----------------IKEHA 598
Query: 467 IFRKIIWKQLLSGDLQKISVGPILPIITDWELAENFDTEFT 507
FR I W++L ++Q P P AENFD FT
Sbjct: 599 FFRYIDWEKLERKEIQP----PYKPKACG-RNAENFDRFFT 634
>Hs20127450 [T] KOG0696 Serine/threonine protein kinase
Length = 673
Score = 164 bits (414), Expect = 4e-40
Identities = 110/341 (32%), Positives = 165/341 (48%), Gaps = 45/341 (13%)
Query: 167 LDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIE 226
L DF + LG+G++G YA+K LKK +++I +D +E T VEKR+
Sbjct: 339 LTDFNFLMVLGKGSFGKVMLSERKGTDELYAVKILKK-DVVIQDDDVEC---TMVEKRVL 394
Query: 227 RTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFY 286
+ L+QL F +LY V++Y+ GG+L YH+++ G E FY
Sbjct: 395 ALPGKPPFLTQLHS--------CFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFY 446
Query: 287 AAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVN 346
AAE++ L FL SKGI+YRDLK +N +L+ GH+ + DFG+ K++++D T
Sbjct: 447 AAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTK------- 499
Query: 347 QLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQE 406
+ GTP+Y APEI+A +PY ++ DW++ G L+Y+ML G+ PF G + + I +
Sbjct: 500 ---TFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEH 556
Query: 407 KTGARIPSYLSDGFKDYLGALLRKDPTKRWDVDKYWAQDGPXXXXXXXXXXXXXNYIGHF 466
P +S L+ K P KR +D H
Sbjct: 557 NVA--YPKSMSKEAVAICKGLMTKHPGKRLGCGPEGERD----------------IKEHA 598
Query: 467 IFRKIIWKQLLSGDLQKISVGPILPIITDWELAENFDTEFT 507
FR I W++L ++Q P P AENFD FT
Sbjct: 599 FFRYIDWEKLERKEIQP----PYKPKACG-RNAENFDRFFT 634
>CE15612 [T] KOG0690 Serine/threonine protein kinase
Length = 541
Score = 164 bits (414), Expect = 4e-40
Identities = 96/270 (35%), Positives = 141/270 (51%), Gaps = 27/270 (10%)
Query: 167 LDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIE 226
++DF ++ LG+G +G YA+K LKK I+ E+ +
Sbjct: 190 MEDFDFLKVLGKGTFGKVILCKEKRTQKLYAIKILKKDVIIAREE-------------VA 236
Query: 227 RTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFY 286
T E +L + +HP + +L YSF + H L V+Q+ GGELF H+++ GT E FY
Sbjct: 237 HTLTENRVLQRCKHPFLTELKYSFQEQHYLCFVMQFANGGELFTHVRKCGTFSEPRARFY 296
Query: 287 AAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSV-FDDAATPEEGENV 345
AE+ AL +LH IVYRD+K EN LL++ GH+ + DFGL K+ + F D +
Sbjct: 297 GAEIVLALGYLHRCDIVYRDMKLENLLLDKDGHIKIADFGLCKEEISFGDKTS------- 349
Query: 346 NQLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQ 405
+ GTPEY APE+L Y + DW+ +G ++Y+M+ G+ PF +H + I
Sbjct: 350 ----TFCGTPEYLAPEVLDDHDYGRCVDWWGVGVVMYEMMCGRLPFYSKDHNKLFELIM- 404
Query: 406 EKTGARIPSYLSDGFKDYLGALLRKDPTKR 435
R PS LS + L LL KDPT+R
Sbjct: 405 -AGDLRFPSKLSQEARTLLTGLLVKDPTQR 433
>Hs10835065 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 277
Score = 163 bits (413), Expect = 6e-40
Identities = 82/242 (33%), Positives = 139/242 (56%), Gaps = 31/242 (12%)
Query: 167 LDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIE 226
L D + +G G +G +A+K + +++ K+ +
Sbjct: 46 LQDCDALVTMGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIR-------------RKQEQ 92
Query: 227 RTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFY 286
E+++L ++ HP +++LF+++H+ LY++++Y+PGGELF +L+ +G T FY
Sbjct: 93 HVHNEKSVLKEVSHPFLIRLFWTWHEERFLYMLMEYVPGGELFSYLRNRGHFSSTTGLFY 152
Query: 287 AAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVN 346
+AE+ CA+++LHSK IVYRDLKPEN LL+ GH+ LTDFG +KK V+
Sbjct: 153 SAEIICAIEYLHSKEIVYRDLKPENILLDRDGHIKLTDFGFAKKL-------------VD 199
Query: 347 QLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPF-----TGVNHKIILN 401
+ +++ GTPEY APE++ + + + DW++LG L+++ML G PPF G+ KI+
Sbjct: 200 RTWTLCGTPEYLAPEVIQSKGHGRAVDWWALGILIFEMLSGFPPFFDDNPFGIYQKILAG 259
Query: 402 KI 403
K+
Sbjct: 260 KL 261
>CE17354 [T] KOG0694 Serine/threonine protein kinase
Length = 567
Score = 163 bits (413), Expect = 6e-40
Identities = 114/356 (32%), Positives = 171/356 (48%), Gaps = 46/356 (12%)
Query: 167 LDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIE 226
L F ++ LG+G++G YAMK LKK IL +D+ E
Sbjct: 235 LPHFNLLKVLGKGSFGKVMLVELKGKNEFYAMKCLKKDVILEDDDT-------------E 281
Query: 227 RTFAERTILSQLEH-PNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAF 285
T+ ER +L P + +LF SF N L+ V++Y+ GG+L +H+++ DE F
Sbjct: 282 CTYIERRVLILASQCPFLCQLFCSFQTNEYLFFVMEYLNGGDLMHHIQQIKKFDEARTRF 341
Query: 286 YAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENV 345
YA E+ AL+FLH+ I+YRDLK +N LL+ GH+ L DFG++K T EN
Sbjct: 342 YACEIVVALQFLHTNNIIYRDLKLDNVLLDCDGHIKLADFGMAK--------TEMNREN- 392
Query: 346 NQLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQ 405
+ GTP+Y +PEI+ G+ Y + D++S G L+Y+ML+G+ PF G + + I
Sbjct: 393 GMASTFCGTPDYISPEIIKGQLYNEAVDFWSFGVLMYEMLVGQSPFHGEGEDELFDSILN 452
Query: 406 EKTGARIPSYLSDGFKDYLGALLRKDPTKRWDVDKYWAQDGPXXXXXXXXXXXXXNYIGH 465
E+ P +S L AL ++P R + + DGP H
Sbjct: 453 ER--PYFPKTISKEAAKCLSALFDRNPNTRLGMPE--CPDGPIRQ--------------H 494
Query: 466 FIFRKIIWKQLLSGDLQKISVGPILPIITDWELAENFDTEFT-EKRLDTSIYDNGI 520
FR + WK+ + + P P I A NFD +FT EK T ++D +
Sbjct: 495 CFFRGVDWKRFENRQVPP----PFKPNIKSNSDASNFDDDFTNEKAALTPVHDKNL 546
>CE17353 [T] KOG0694 Serine/threonine protein kinase
Length = 704
Score = 163 bits (413), Expect = 6e-40
Identities = 114/356 (32%), Positives = 171/356 (48%), Gaps = 46/356 (12%)
Query: 167 LDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIE 226
L F ++ LG+G++G YAMK LKK IL +D+ E
Sbjct: 372 LPHFNLLKVLGKGSFGKVMLVELKGKNEFYAMKCLKKDVILEDDDT-------------E 418
Query: 227 RTFAERTILSQLEH-PNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAF 285
T+ ER +L P + +LF SF N L+ V++Y+ GG+L +H+++ DE F
Sbjct: 419 CTYIERRVLILASQCPFLCQLFCSFQTNEYLFFVMEYLNGGDLMHHIQQIKKFDEARTRF 478
Query: 286 YAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENV 345
YA E+ AL+FLH+ I+YRDLK +N LL+ GH+ L DFG++K T EN
Sbjct: 479 YACEIVVALQFLHTNNIIYRDLKLDNVLLDCDGHIKLADFGMAK--------TEMNREN- 529
Query: 346 NQLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQ 405
+ GTP+Y +PEI+ G+ Y + D++S G L+Y+ML+G+ PF G + + I
Sbjct: 530 GMASTFCGTPDYISPEIIKGQLYNEAVDFWSFGVLMYEMLVGQSPFHGEGEDELFDSILN 589
Query: 406 EKTGARIPSYLSDGFKDYLGALLRKDPTKRWDVDKYWAQDGPXXXXXXXXXXXXXNYIGH 465
E+ P +S L AL ++P R + + DGP H
Sbjct: 590 ER--PYFPKTISKEAAKCLSALFDRNPNTRLGMPE--CPDGPIRQ--------------H 631
Query: 466 FIFRKIIWKQLLSGDLQKISVGPILPIITDWELAENFDTEFT-EKRLDTSIYDNGI 520
FR + WK+ + + P P I A NFD +FT EK T ++D +
Sbjct: 632 CFFRGVDWKRFENRQVPP----PFKPNIKSNSDASNFDDDFTNEKAALTPVHDKNL 683
>At5g09890 [R] KOG0605 NDR and related serine/threonine kinases
Length = 495
Score = 163 bits (413), Expect = 6e-40
Identities = 99/298 (33%), Positives = 151/298 (50%), Gaps = 49/298 (16%)
Query: 167 LDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIE 226
+DDF + +G+GA+G YAMK+LKK E+L ++E
Sbjct: 99 IDDFELLTVIGKGAFGEVRLCRLRSTSEVYAMKKLKKTEMLS-------------RGQVE 145
Query: 227 RTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFY 286
+ER +L++++ IVKLFYSF D+ LYL+++Y+PGG++ L + L E FY
Sbjct: 146 HVRSERNLLAEVDSRYIVKLFYSFQDSECLYLIMEYLPGGDIMTLLMREDILSEDVARFY 205
Query: 287 AAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKK--------SVFDDAAT 338
AE A+ +H V+RD+KP+N +L++ GHL L+DFGL K + DD
Sbjct: 206 IAESILAIHSIHQHNYVHRDIKPDNLILDKSGHLKLSDFGLCKPLDDKYSSLLLEDDEML 265
Query: 339 PEEGENVN---------------QL-----------YSIIGTPEYCAPEILAGEPYTQNC 372
++ EN + QL YS +GT +Y APE+L + Y C
Sbjct: 266 SQDSENQSGKSDADKAPWQMPKEQLLQWKRNRRALAYSTVGTLDYMAPEVLLKKGYGMEC 325
Query: 373 DWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQEKTGARIPS--YLSDGFKDYLGALL 428
DW+SLG ++Y+ML+G PPF + +I KI + + P +SD +D + LL
Sbjct: 326 DWWSLGAILYEMLVGYPPFCSDDPRITCRKIINWRVCLKFPEEPKISDEARDLICRLL 383
>At4g14350 [R] KOG0605 NDR and related serine/threonine kinases
Length = 475
Score = 163 bits (413), Expect = 6e-40
Identities = 104/328 (31%), Positives = 157/328 (47%), Gaps = 51/328 (15%)
Query: 134 SDKETRDVLSVSSVEETRQLRASSFSKTGAPRVLDDFVPIRCLGEGAYGXXXXXXXXXXX 193
S++E ++L ++ET +R K GA DDF P+ +G+GA+G
Sbjct: 12 SEEEQNNLLKDLEMKETEYMRRQRH-KMGA----DDFEPLTMIGKGAFGEVRICREKGTG 66
Query: 194 XXYAMKQLKKAEILISEDSIEKDANTTVEKRIERTFAERTILSQLEHPNIVKLFYSFHDN 253
YAMK+LKK+E+L ++E AER +L++++ IVKL+ SF D
Sbjct: 67 NVYAMKKLKKSEMLR-------------RGQVEHVKAERNLLAEVDSNCIVKLYCSFQDE 113
Query: 254 HKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAAELSCALKFLHSKGIVYRDLKPENCL 313
LYL+++Y+PGG++ L + TL E FY E A++ +H ++RD+KP+N L
Sbjct: 114 EYLYLIMEYLPGGDMMTLLMRKDTLTEDEARFYIGETVLAIESIHKHNYIHRDIKPDNLL 173
Query: 314 LNERGHLVLTDFGLSK------------------KSVFDDAATPEEGENVNQ-------- 347
L++ GH+ L+DFGL K P Q
Sbjct: 174 LDKDGHMKLSDFGLCKPLDCSNLQEKDFTVARNVSGALQSDGRPVATRRTQQEQLLNWQR 233
Query: 348 -----LYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNK 402
YS +GTP+Y APE+L + Y CDW+SLG ++Y+ML+G PPF + K
Sbjct: 234 NRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGFPPFYSDDPMTTCRK 293
Query: 403 IKQEKTGARIPS--YLSDGFKDYLGALL 428
I + + P LS KD + LL
Sbjct: 294 IVNWRNYLKFPDEVRLSPEAKDLICRLL 321
>7303915 [T] KOG0694 Serine/threonine protein kinase
Length = 590
Score = 163 bits (413), Expect = 6e-40
Identities = 125/433 (28%), Positives = 199/433 (45%), Gaps = 57/433 (13%)
Query: 91 PDSGESKQSQTKEPARRRSSLYNKFVVNPAQHTIRLSL---------NAQGDSDKETRDV 141
P + Q Q K+P +++ N++ +N A+ S+ N+ ++ R+V
Sbjct: 172 PQFPQPAQRQEKQPPQQQPIYANQYELNVAKAAAAASVYSPSSSTTSNSNQQQQQQRRNV 231
Query: 142 LSVSSVEETRQL---RASSFSKTGAPRVLDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAM 198
E+ L RA +D+F + LG G +G YA+
Sbjct: 232 ARGLQYRESGGLETGRAGKQPPNAGMLSMDNFRLLSVLGRGHFGKVILSQLRSNNQYYAI 291
Query: 199 KQLKKAEILISEDSIEKDANTTVEKRIERTFAERTILSQLEHPNIVKLFYSFHDNHKLYL 258
K LKK +I I+ D +E + EKRI + + + HP +V L+ F +
Sbjct: 292 KALKKGDI-IARDEVE---SLLSEKRIFE------VANAMRHPFLVNLYSCFQTEQHVCF 341
Query: 259 VLQYIPGGELFYHLKEQGTLDEGTVAFYAAELSCALKFLHSKGIVYRDLKPENCLLNERG 318
V++Y GG+L H+ L+ V FYAA + L++LH I+YRDLK +N LL+ G
Sbjct: 342 VMEYAAGGDLMMHIHTDVFLEPRAV-FYAACVVLGLQYLHENKIIYRDLKLDNLLLDTEG 400
Query: 319 HLVLTDFGLSKKSV-FDDAATPEEGENVNQLYSIIGTPEYCAPEILAGEPYTQNCDWYSL 377
++ + DFGL K+ + F D + GTPE+ APE+L YT+ DW+ L
Sbjct: 401 YVKIADFGLCKEGMGFGDRTG-----------TFCGTPEFLAPEVLTETSYTRAVDWWGL 449
Query: 378 GCLVYDMLIGKPPFTGVNHKIILNKIKQEKTGARIPSYLSDGFKDYLGALLRKDPTKRWD 437
G L+++ML+G+ PF G + + + + I ++ R P +LS + LLRK+P +R
Sbjct: 450 GVLIFEMLVGESPFPGDDEEEVFDSIVNDE--VRYPRFLSLEAIAVMRRLLRKNPERRLG 507
Query: 438 VDKYWAQDGPXXXXXXXXXXXXXNYIGHFIFRKIIWKQLLSGDLQKISVGPILPIITDWE 497
+ A+D FR I+W LL L+K+ P +P I E
Sbjct: 508 SSERDAEDVKKQA----------------FFRSIVWDDLL---LRKVK-PPFVPTINHLE 547
Query: 498 LAENFDTEFTEKR 510
NFD EFT ++
Sbjct: 548 DVSNFDEEFTSEK 560
>7303914 [T] KOG0694 Serine/threonine protein kinase
Length = 1284
Score = 163 bits (413), Expect = 6e-40
Identities = 125/433 (28%), Positives = 199/433 (45%), Gaps = 57/433 (13%)
Query: 91 PDSGESKQSQTKEPARRRSSLYNKFVVNPAQHTIRLSL---------NAQGDSDKETRDV 141
P + Q Q K+P +++ N++ +N A+ S+ N+ ++ R+V
Sbjct: 866 PQFPQPAQRQEKQPPQQQPIYANQYELNVAKAAAAASVYSPSSSTTSNSNQQQQQQRRNV 925
Query: 142 LSVSSVEETRQL---RASSFSKTGAPRVLDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAM 198
E+ L RA +D+F + LG G +G YA+
Sbjct: 926 ARGLQYRESGGLETGRAGKQPPNAGMLSMDNFRLLSVLGRGHFGKVILSQLRSNNQYYAI 985
Query: 199 KQLKKAEILISEDSIEKDANTTVEKRIERTFAERTILSQLEHPNIVKLFYSFHDNHKLYL 258
K LKK +I I+ D +E + EKRI + + + HP +V L+ F +
Sbjct: 986 KALKKGDI-IARDEVE---SLLSEKRIFE------VANAMRHPFLVNLYSCFQTEQHVCF 1035
Query: 259 VLQYIPGGELFYHLKEQGTLDEGTVAFYAAELSCALKFLHSKGIVYRDLKPENCLLNERG 318
V++Y GG+L H+ L+ V FYAA + L++LH I+YRDLK +N LL+ G
Sbjct: 1036 VMEYAAGGDLMMHIHTDVFLEPRAV-FYAACVVLGLQYLHENKIIYRDLKLDNLLLDTEG 1094
Query: 319 HLVLTDFGLSKKSV-FDDAATPEEGENVNQLYSIIGTPEYCAPEILAGEPYTQNCDWYSL 377
++ + DFGL K+ + F D + GTPE+ APE+L YT+ DW+ L
Sbjct: 1095 YVKIADFGLCKEGMGFGDRTG-----------TFCGTPEFLAPEVLTETSYTRAVDWWGL 1143
Query: 378 GCLVYDMLIGKPPFTGVNHKIILNKIKQEKTGARIPSYLSDGFKDYLGALLRKDPTKRWD 437
G L+++ML+G+ PF G + + + + I ++ R P +LS + LLRK+P +R
Sbjct: 1144 GVLIFEMLVGESPFPGDDEEEVFDSIVNDE--VRYPRFLSLEAIAVMRRLLRKNPERRLG 1201
Query: 438 VDKYWAQDGPXXXXXXXXXXXXXNYIGHFIFRKIIWKQLLSGDLQKISVGPILPIITDWE 497
+ A+D FR I+W LL L+K+ P +P I E
Sbjct: 1202 SSERDAEDVKKQA----------------FFRSIVWDDLL---LRKVK-PPFVPTINHLE 1241
Query: 498 LAENFDTEFTEKR 510
NFD EFT ++
Sbjct: 1242 DVSNFDEEFTSEK 1254
>Hs4505695 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 556
Score = 162 bits (411), Expect = 9e-40
Identities = 94/268 (35%), Positives = 143/268 (53%), Gaps = 23/268 (8%)
Query: 168 DDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIER 227
+DF + LGEG++ YA+K L+K I+ E ++
Sbjct: 80 EDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHII-------------KENKVPY 126
Query: 228 TFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYA 287
ER ++S+L+HP VKL+++F D+ KLY L Y GEL ++++ G+ DE FY
Sbjct: 127 VTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYT 186
Query: 288 AELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVNQ 347
AE+ AL++LH KGI++RDLKPEN LLNE H+ +TDFG +K +PE + +
Sbjct: 187 AEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAK------VLSPESKQ--AR 238
Query: 348 LYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQEK 407
S +GT +Y +PE+L + ++ D ++LGC++Y ++ G PPF N +I KI K
Sbjct: 239 ANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKI--IK 296
Query: 408 TGARIPSYLSDGFKDYLGALLRKDPTKR 435
P +D + LL D TKR
Sbjct: 297 LEYDFPEKFFPKARDLVEKLLVLDATKR 324
>7294770 [T] KOG0603 Ribosomal protein S6 kinase
Length = 1207
Score = 162 bits (410), Expect = 1e-39
Identities = 131/415 (31%), Positives = 193/415 (45%), Gaps = 63/415 (15%)
Query: 105 ARRRSSLYNKFVVNPAQHTIRLSLNAQGDSDKETRDVLSVSSVEETRQLRASSFSKTGAP 164
A + SS P ++ L L D++ RD+ +V+ ++ +L +
Sbjct: 206 ASKASSSTTPSYAMPTSNSTPLDL----DNEAHQRDLEAVTDLKYYVKLYSDEAVS---- 257
Query: 165 RVLDDFVPIRCLGEGAYGXXXXXXXXXXXXX---YAMKQLKKAEILISEDSIEKDANTTV 221
L+DF IR LG GAYG YAMK L K T V
Sbjct: 258 --LNDFKIIRVLGTGAYGRVFLVRKLTRHDAGKLYAMKVLNKI--------------TVV 301
Query: 222 EKR--IERTFAERTILSQLE-HPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTL 278
+KR E T ER +L ++ +P +V L Y+F + KLYLVL + GGELF HL
Sbjct: 302 QKRKTAEHTKTERVVLEAIQRNPFLVSLHYAFQSSSKLYLVLDFANGGELFTHLYHSENF 361
Query: 279 DEGTVAFYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAAT 338
+E V Y AE+ AL+ LH GI+YRD+K EN LL+ GH+VL+DFGLSK
Sbjct: 362 EESRVRVYIAEVVLALEQLHQLGIIYRDIKLENILLDGEGHIVLSDFGLSKILT------ 415
Query: 339 PEEGENVNQLYSIIGTPEYCAPEILAGEP--YTQNCDWYSLGCLVYDMLIGKPPFTGVNH 396
EN + +S GT EY APEI+ P + DW+S+G L +++L G PF +
Sbjct: 416 ---AENEYRAHSFCGTLEYMAPEIIRTGPPGHDSAVDWWSVGVLTFELLTGASPFATSDG 472
Query: 397 KIILNKIKQ--EKTGARIPSYLSDGFKDYLGALLRKDPTKRWDVDKYWAQDGPXXXXXXX 454
++ ++I + +K IPS S +D++ +L K+P +R + A +
Sbjct: 473 QVQQSEISRRIQKEQPMIPSSFSANARDFVLKMLEKNPKRRLGGNHRDASE--------- 523
Query: 455 XXXXXXNYIGHFIFRKIIWKQLLSGDLQKISVGPILPIITDWELAENFDTEFTEK 509
H F I W++L + K P P +T + +NF EFT++
Sbjct: 524 -------IKEHPFFNGINWQELRT----KRRKAPYKPTLTAEDDVQNFSNEFTDQ 567
Score = 62.8 bits (151), Expect = 1e-09
Identities = 59/236 (25%), Positives = 100/236 (42%), Gaps = 42/236 (17%)
Query: 235 LSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAAELSCAL 294
L H NIV +F + + ++V++Y+ G EL ++ +DE + +L A+
Sbjct: 672 LDTTNHKNIVSYHGTFREKCETWIVMEYLSGPELTASIR----MDEDSCREIFLQLVMAV 727
Query: 295 KFLHSKGIVYRDLKPENCLLNERGH--LVLTDFGLSKKSVFDDAATPEEGENVNQLYSII 352
+ +HSK ++ DLKPEN + R + L DFG + + N+ S
Sbjct: 728 RHIHSKHFIHGDLKPENIMFENREDRTVKLIDFGSACYN--------------NRFKSWK 773
Query: 353 GTP----EYCAPEILAGE---PYTQNCDWYSLGCLVYDMLIGKPPF---------TGVNH 396
P +Y PE+LA Y+ D Y LG +Y ML+G P+ + H
Sbjct: 774 DKPRYTLDYAPPEMLADANLVTYSPAVDIYGLGATLYTMLVGHRPYRQNEDDVDHSAAAH 833
Query: 397 KIILNKIKQEKTGARIPSY--LSDGFKDYLGALLRKDPTKRWD----VDKYWAQDG 446
+ ++++ R + S F+ + L++DP R +D W Q G
Sbjct: 834 HELRKRMRRGTFNQRSMRWESASPAFRHLVSWCLQRDPADRPTLSDILDSEWLQYG 889
>YNR047w [R] KOG0610 Putative serine/threonine protein kinase
Length = 893
Score = 160 bits (405), Expect = 5e-39
Identities = 104/304 (34%), Positives = 151/304 (49%), Gaps = 34/304 (11%)
Query: 150 TRQLRASSFSKTGAPRVL--DDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEIL 207
+R+LR SFS ++ F IR LG+G G YA+K L K E++
Sbjct: 474 SRRLRTKSFSNKFQDIMVGPQSFEKIRLLGQGDVGKVFLVREKKTNRVYALKVLSKDEMI 533
Query: 208 ISEDSIEKDANTTVEKRIERTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGE 267
+I+R E+ IL+ HP IV L++SF LYL ++Y GGE
Sbjct: 534 -------------KRNKIKRVLTEQEILATSNHPFIVTLYHSFQSEDYLYLCMEYCMGGE 580
Query: 268 LFYHLKEQGT--LDEGTVAFYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDF 325
F L+ + T + E FYA+E++ AL++LH G +YRDLKPEN LL++ GH++L+DF
Sbjct: 581 FFRALQTRKTKCICEDDARFYASEVTAALEYLHLLGFIYRDLKPENILLHQSGHIMLSDF 640
Query: 326 GLS--------------KKSVFDDAATPEEGENVNQLYSIIGTPEYCAPEILAGEPYTQN 371
LS +S D +G N S +GT EY APE++ G +T
Sbjct: 641 DLSIQAKDSKVPVVKGSAQSTLVDTKICSDGFRTN---SFVGTEEYIAPEVIRGNGHTAA 697
Query: 372 CDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQEKTGARIPSYLSDGFKDYLGALLRKD 431
DW++LG L+Y+ML G PF G N I + + + +S KD + LL K+
Sbjct: 698 VDWWTLGILIYEMLFGFTPFKGDNTNETFTNILKNEVSFPNNNEISRTCKDLIKKLLTKN 757
Query: 432 PTKR 435
+KR
Sbjct: 758 ESKR 761
>YCR091w [R] KOG0610 Putative serine/threonine protein kinase
Length = 720
Score = 160 bits (405), Expect = 5e-39
Identities = 112/361 (31%), Positives = 166/361 (45%), Gaps = 54/361 (14%)
Query: 150 TRQLRASSFSKTGAPRVLD--DFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEIL 207
+R+LR SF ++ F IR LG+G G +A+K L K E++
Sbjct: 302 SRRLRTKSFGNKFQDITVEPQSFEKIRLLGQGDVGKVYLMRERDTNQIFALKVLNKHEMI 361
Query: 208 ISEDSIEKDANTTVEKRIERTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGE 267
K+I+R E+ IL+ +HP IV L++SF LYL ++Y GGE
Sbjct: 362 -------------KRKKIKRVLTEQEILATSDHPFIVTLYHSFQTKDYLYLCMEYCMGGE 408
Query: 268 LFYHLKEQGT--LDEGTVAFYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDF 325
F L+ + + + E FYA+E+ AL++LH G +YRDLKPEN LL++ GH++L+DF
Sbjct: 409 FFRALQTRKSKCIAEEDAKFYASEVVAALEYLHLLGFIYRDLKPENILLHQSGHVMLSDF 468
Query: 326 GLS-----------KKSVFDDAATPEEGENVNQLYSIIGTPEYCAPEILAGEPYTQNCDW 374
LS K S + D +G N S +GT EY APE++ G +T DW
Sbjct: 469 DLSIQATGSKKPTMKDSTYLDTKICSDGFRTN---SFVGTEEYLAPEVIRGNGHTAAVDW 525
Query: 375 YSLGCLVYDMLIGKPPFTGVNHKIILNKIKQEKTGARIPSYLSDGFKDYLGALLRKDPTK 434
++LG L+Y+ML G PF G N + I + +S KD + LL K+ K
Sbjct: 526 WTLGILIYEMLFGCTPFKGDNSNETFSNILTKDVKFPHDKEVSKNCKDLIKKLLNKNEAK 585
Query: 435 RWDVDKYWAQDGPXXXXXXXXXXXXXNYIGHFIFRKIIWKQLLSGDLQKISVGPILPIIT 494
R + H F+K+ W L + D P++P +
Sbjct: 586 R-----------------LGSKSGAADIKRHPFFKKVQWSFLRNQD------PPLIPALN 622
Query: 495 D 495
D
Sbjct: 623 D 623
>Hs18579683 [R] KOG0605 NDR and related serine/threonine kinases
Length = 464
Score = 160 bits (405), Expect = 5e-39
Identities = 99/296 (33%), Positives = 157/296 (52%), Gaps = 43/296 (14%)
Query: 121 QHTIRLSLNAQGDSDKETRDVLSVSSVEETRQLRASSFSKTGAPRVLDDFVPIRCLGEGA 180
Q + +++ +G +D+E + S + +ET LR ++ G LDDF ++ +G GA
Sbjct: 46 QKKLEVAMEEEGLADEEKKLRRSQHARKETEFLRLKR-TRLG----LDDFESLKVIGRGA 100
Query: 181 YGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIERTFAERTILSQLEH 240
+G YAMK L+K+++L E ++ AER IL + +
Sbjct: 101 FGEVRLVQKKDTGHIYAMKILRKSDMLEKE-------------QVAHIRAERDILVEADG 147
Query: 241 PNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAAELSCALKFLHSK 300
+VK+FYSF D LYL+++++PGG++ L ++ TL E FY +E A+ +H
Sbjct: 148 AWVVKMFYSFQDKRNLYLIMEFLPGGDMMTLLMKKDTLTEEETQFYISETVLAIDAIHQL 207
Query: 301 GIVYRDLKPENCLLNERGHLVLTDFGLS---KKS-----------------VFDDAATPE 340
G ++RD+KP+N LL+ +GH+ L+DFGL KK+ F + +
Sbjct: 208 GFIHRDIKPDNLLLDAKGHVKLSDFGLCTGLKKAHRTEFYRNLTHNPPSDFSFQNMNSKR 267
Query: 341 EGE----NVNQL-YSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPF 391
+ E N QL YS +GTP+Y APE+ Y + CDW+SLG ++Y+MLIG PPF
Sbjct: 268 KAETWKKNRRQLAYSTVGTPDYIAPEVFMQTGYNKLCDWWSLGVIMYEMLIGYPPF 323
>SPBC12D12.04c [T] KOG0694 Serine/threonine protein kinase
Length = 1016
Score = 160 bits (404), Expect = 6e-39
Identities = 115/379 (30%), Positives = 178/379 (46%), Gaps = 55/379 (14%)
Query: 167 LDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIE 226
L+DF + LG+G +G YA+K LKK E ++ D +E +T EKR+
Sbjct: 680 LEDFTFLSVLGKGNFGKVMLAELKSEKQLYAIKVLKK-EFILENDEVE---STKSEKRVF 735
Query: 227 RTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFY 286
+ ++ HP +V L F ++Y V+ ++ GG+L H++++ FY
Sbjct: 736 ------LVANRERHPFLVNLHSCFQTETRIYFVMDFVSGGDLMLHIQQE-QFSRRRAQFY 788
Query: 287 AAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVN 346
AAE+ ALK+ H GI+YRDLK +N LL+ GH+ + D+GL K+ ++ D N
Sbjct: 789 AAEVCLALKYFHDNGIIYRDLKLDNILLSPDGHVKVADYGLCKEDMWHD----------N 838
Query: 347 QLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQE 406
+ GTPE+ APEIL + YT++ DW++ G L+Y ML+G+ PF G + + I + I +
Sbjct: 839 TTATFCGTPEFMAPEILLEQQYTRSVDWWAFGVLIYQMLLGQSPFRGEDEEEIFDAILSD 898
Query: 407 KTGARIPSYLSDGFKDYLGALLRKDPTKRWDVDKYWAQDGPXXXXXXXXXXXXXNYIGHF 466
+ P ++ L LL +DP KR A+D + H
Sbjct: 899 E--PLYPIHMPRDSVSILQQLLTRDPKKRLGSGPNDAED----------------VMTHP 940
Query: 467 IFRKIIWKQLLSGDLQKISVGPILPIITDWELAENFDTEFTEKRLDTSIYDNGIEINNPR 526
F I W + K + P +P + + FD EFT + L N I
Sbjct: 941 FFSNINWDDI----YHKRTQPPYIPSLNSPTDTKYFDEEFT-RELPVLTPVNSI------ 989
Query: 527 ATKESAFAGSTDYFKGFSY 545
TKE +F+GFSY
Sbjct: 990 LTKE-----MQQHFEGFSY 1003
>CE28744 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 879
Score = 159 bits (402), Expect = 1e-38
Identities = 110/342 (32%), Positives = 162/342 (47%), Gaps = 52/342 (15%)
Query: 169 DFVPIRCLGEGAYGXXXXXXXXXXX---XXYAMKQLKKAEILISEDSIEKDANTTVEKRI 225
DF ++ +GEG YG YAMK + K ++ T EK +
Sbjct: 22 DFERLKLVGEGGYGKVFQVRKQTGEDKGTIYAMKVITKRKV------------TGTEKDL 69
Query: 226 ERTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAF 285
ER IL + P + L Y+F N KLYLVL+++ GGEL+ L+ + E F
Sbjct: 70 RHARDERKILETINSPFLCDLHYAFQTNEKLYLVLEFLHGGELYTLLERKSDWPEEYARF 129
Query: 286 YAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENV 345
Y +E+ A++ LH IVYRDLKP+N +LN GH+VLTDFGL K + ++GE
Sbjct: 130 YLSEIILAIEHLHGHDIVYRDLKPDNVMLNLAGHVVLTDFGLCKYKL-------KKGE-- 180
Query: 346 NQLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQ 405
+ + GT EY APE++ + D ++LG L+YDM +G PPFTG I +
Sbjct: 181 -KTLTFCGTHEYMAPEMIRKVGHDHAVDVWALGILMYDMFMGGPPFTGETPADKDKSILK 239
Query: 406 EKTGARIPSYLSDGFKDYLGALLRKDPTKRWDVDKYWAQDGPXXXXXXXXXXXXXNYIGH 465
K R+P LS KD + ++++DPT R + + H
Sbjct: 240 GK--VRLPPKLSASGKDLIKRIIKRDPTLRITIP---------------------DIKEH 276
Query: 466 FIFRKIIWKQLLSGDLQKISVGPILPIITDWELAENFDTEFT 507
F +I W +L++ D + P P + + E +FD FT
Sbjct: 277 EFFEEIDWDKLMAHDFEP----PFKPTLANLEDVSHFDESFT 314
>Hs6005814 [R] KOG0605 NDR and related serine/threonine kinases
Length = 465
Score = 159 bits (401), Expect = 1e-38
Identities = 103/318 (32%), Positives = 159/318 (49%), Gaps = 43/318 (13%)
Query: 121 QHTIRLSLNAQGDSDKETRDVLSVSSVEETRQLRASSFSKTGAPRVLDDFVPIRCLGEGA 180
Q + + +G D+E R S + +ET LR ++ G L+DF ++ +G GA
Sbjct: 45 QKKLEKVMEEEGLKDEEKRLRRSAHARKETEFLRLKR-TRLG----LEDFESLKVIGRGA 99
Query: 181 YGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIERTFAERTILSQLEH 240
+G YAMK L+KA++L E ++ AER IL + +
Sbjct: 100 FGEVRLVQKKDTGHVYAMKILRKADMLEKE-------------QVGHIRAERDILVEADS 146
Query: 241 PNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAAELSCALKFLHSK 300
+VK+FYSF D LYL+++++PGG++ L ++ TL E FY AE A+ +H
Sbjct: 147 LWVVKMFYSFQDKLNLYLIMEFLPGGDMMTLLMKKDTLTEEETQFYIAETVLAIDSIHQL 206
Query: 301 GIVYRDLKPENCLLNERGHLVLTDFGLS---KKS-----------------VFDDAATPE 340
G ++RD+KP+N LL+ +GH+ L+DFGL KK+ F + +
Sbjct: 207 GFIHRDIKPDNLLLDSKGHVKLSDFGLCTGLKKAHRTEFYRNLNHSLPSDFTFQNMNSKR 266
Query: 341 EGE----NVNQL-YSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVN 395
+ E N QL +S +GTP+Y APE+ Y + CDW+SLG ++Y+MLIG PPF
Sbjct: 267 KAETWKRNRRQLAFSTVGTPDYIAPEVFMQTGYNKLCDWWSLGVIMYEMLIGYPPFCSET 326
Query: 396 HKIILNKIKQEKTGARIP 413
+ K+ K P
Sbjct: 327 PQETYKKVMNWKETLTFP 344
>SPAC1B9.02c [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 696
Score = 157 bits (398), Expect = 3e-38
Identities = 122/385 (31%), Positives = 175/385 (44%), Gaps = 56/385 (14%)
Query: 168 DDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIER 227
+DF +R +G+G +G YAMK++ K I+ +K +
Sbjct: 300 EDFTALRLIGKGTFGQVYLVRKNDTNRIYAMKKISKKLIVR-------------KKEVTH 346
Query: 228 TFAERTILSQL---EHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVA 284
T ER IL + E P IV L +SF LYL+ Y+ GGELF+HL+ +G E
Sbjct: 347 TLGERNILVRTSLDESPFIVGLKFSFQTASDLYLITDYMSGGELFWHLQHEGRFPEQRAK 406
Query: 285 FYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGEN 344
FY AEL AL+ LH I+YRDLKPEN LL+ GH+ L DFGLSK ++ +A T
Sbjct: 407 FYIAELVLALEHLHKHDIIYRDLKPENILLDADGHIALCDFGLSKANLSANATT------ 460
Query: 345 VNQLYSIIGTPEYCAPEILAGEP-YTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKI 403
+ GT EY APE+L + YT+ D++SLG LV++M G PF + + + I
Sbjct: 461 ----NTFCGTTEYLAPEVLLEDKGYTKQVDFWSLGVLVFEMCCGWSPFYAPDVQQMYRNI 516
Query: 404 KQEKTGARIP-SYLSDGFKDYLGALLRKDPTKRWDVDKYWAQDGPXXXXXXXXXXXXXNY 462
K R P LS + ++ LL ++P R
Sbjct: 517 AFGK--VRFPKGVLSSEGRSFVRGLLNRNPNHR-----------------LGAVADTTEL 557
Query: 463 IGHFIFRKIIWKQLLSGDLQKISVGPILPIITDWELAENFDTEFTEKRLDTSIYDNGIEI 522
H F I W L +Q P P + + NFD EFT +T++ + I
Sbjct: 558 KEHPFFADINWDLLSKKKVQP----PFKPNVQNDLDVSNFDKEFT----NTNVKNINIVS 609
Query: 523 NNPRATKESAFAGS-TDYFKGFSYV 546
N A + + + D F+GF++V
Sbjct: 610 NVDPANASTPLSNTIQDRFRGFTFV 634
>7293735 [R] KOG0605 NDR and related serine/threonine kinases
Length = 459
Score = 157 bits (398), Expect = 3e-38
Identities = 89/265 (33%), Positives = 139/265 (51%), Gaps = 41/265 (15%)
Query: 167 LDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIE 226
++DF ++ +G GA+G YAMK L+KA++L E ++
Sbjct: 90 VEDFEALKVIGRGAFGEVRLVQKKDTGHVYAMKVLRKADMLEKE-------------QVA 136
Query: 227 RTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFY 286
AER +L + +H +VK++YSF D LYL+++++PGG++ L ++ TL E FY
Sbjct: 137 HVRAERDVLVEADHQWVVKMYYSFQDPVNLYLIMEFLPGGDMMTLLMKKDTLSEEGTQFY 196
Query: 287 AAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLS---KKSVFDD-------- 335
+E + A+ +H G ++RD+KP+N LL+ RGHL L+DFGL KKS D
Sbjct: 197 ISETALAIDSIHKLGFIHRDIKPDNLLLDARGHLKLSDFGLCTGLKKSHRTDFYRDLSQA 256
Query: 336 --------AATPEEGENVNQ---------LYSIIGTPEYCAPEILAGEPYTQNCDWYSLG 378
A+P + + + YS +GTP+Y APE+ Y CDW+SLG
Sbjct: 257 KPSDFIGTCASPMDSKRRAESWKRNRRALAYSTVGTPDYIAPEVFLQTGYGPACDWWSLG 316
Query: 379 CLVYDMLIGKPPFTGVNHKIILNKI 403
++Y+ML+G PPF N + K+
Sbjct: 317 VIMYEMLMGYPPFCSDNPQDTYRKV 341
>Hs4758666 [D] KOG0608 Warts/lats-like serine threonine kinases
Length = 1130
Score = 157 bits (397), Expect = 4e-38
Identities = 89/281 (31%), Positives = 138/281 (48%), Gaps = 50/281 (17%)
Query: 170 FVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIERTF 229
FV I+ LG GA+G YA K L+K ++L+ ++
Sbjct: 705 FVKIKTLGIGAFGEVCLARKVDTKALYATKTLRKKDVLL-------------RNQVAHVK 751
Query: 230 AERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAAE 289
AER IL++ ++ +V+L+YSF D LY V+ YIPGG++ L G E FY AE
Sbjct: 752 AERDILAEADNEWVVRLYYSFQDKDNLYFVMDYIPGGDMMSLLIRMGIFPESLARFYIAE 811
Query: 290 LSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSK-------------------- 329
L+CA++ +H G ++RD+KP+N L++ GH+ LTDFGL
Sbjct: 812 LTCAVESVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHDSKYYQSGDHPRQD 871
Query: 330 ----KSVFDDAATPEEGENVNQL-------------YSIIGTPEYCAPEILAGEPYTQNC 372
+ + D ++ G+ + L +S++GTP Y APE+L YTQ C
Sbjct: 872 SMDFSNEWGDPSSCRCGDRLKPLERRAARQHQRCLAHSLVGTPNYIAPEVLLRTGYTQLC 931
Query: 373 DWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQEKTGARIP 413
DW+S+G ++++ML+G+PPF K+ +T IP
Sbjct: 932 DWWSVGVILFEMLVGQPPFLAQTPLETQMKVINWQTSLHIP 972
>At4g33080 [R] KOG0605 NDR and related serine/threonine kinases
Length = 483
Score = 156 bits (395), Expect = 7e-38
Identities = 96/303 (31%), Positives = 153/303 (49%), Gaps = 54/303 (17%)
Query: 167 LDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIE 226
+DDF + +G GA+G YAMK+LKK+E+++ ++E
Sbjct: 91 VDDFELLTIIGRGAFGEVRLCRERKSGNIYAMKKLKKSEMVM-------------RGQVE 137
Query: 227 RTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFY 286
AER +L+++E IVKL+YSF D LYL+++Y+PGG++ L + TL E FY
Sbjct: 138 HVRAERNLLAEVESHYIVKLYYSFQDPEYLYLIMEYLPGGDMMTLLMREDTLREDVARFY 197
Query: 287 AAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSK-------KSVFDDAATP 339
A+ A++ +H ++RD+KP+N LL++ GH+ L+DFGL K S+ ++ AT
Sbjct: 198 IAQSVLAIESIHRYNYIHRDIKPDNLLLDKDGHMKLSDFGLCKPLDCRNLPSIQENRATD 257
Query: 340 EEGEN-----------------------------VNQ---LYSIIGTPEYCAPEILAGEP 367
+E + +N+ +S +GTP+Y APE+L +
Sbjct: 258 DETMSEPMDVDRCFPDTDNKRSWRSPQEQLQHWQMNRRKLAFSTVGTPDYIAPEVLLKKG 317
Query: 368 YTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQEKTGARIP--SYLSDGFKDYLG 425
Y CDW+SLG ++Y+ML+G PPF + KI + + P + S KD +
Sbjct: 318 YGMECDWWSLGAIMYEMLVGYPPFYADDPISTCRKIVHWRNHLKFPEDAKFSSEAKDLIC 377
Query: 426 ALL 428
LL
Sbjct: 378 RLL 380
>YHR205w [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 824
Score = 155 bits (393), Expect = 1e-37
Identities = 129/389 (33%), Positives = 177/389 (45%), Gaps = 54/389 (13%)
Query: 169 DFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIERT 228
DF +R LG+G +G YAMK L K ++++ ++ I A+T E+ I T
Sbjct: 411 DFEVLRLLGKGTFGQVYQVKKKDTQRIYAMKVLSK-KVIVKKNEI---AHTIGERNILVT 466
Query: 229 FAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAA 288
A ++ P IV L +SF LYLV Y+ GGELF+HL+++G E FY A
Sbjct: 467 TASKS------SPFIVGLKFSFQTPTDLYLVTDYMSGGELFWHLQKEGRFSEDRAKFYIA 520
Query: 289 ELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVNQL 348
EL AL+ LH IVYRDLKPEN LL+ G++ L DFGLSK + D T
Sbjct: 521 ELVLALEHLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRTNT---------- 570
Query: 349 YSIIGTPEYCAPEILAGEP-YTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQEK 407
GT EY APE+L E YT+ D++SLG L+++M G PF N++ + KI K
Sbjct: 571 --FCGTTEYLAPELLLDETGYTKMVDFWSLGVLIFEMCCGWSPFFAENNQKMYQKIAFGK 628
Query: 408 TGARIP-SYLSDGFKDYLGALLRKDPTKRWDVDKYWAQDGPXXXXXXXXXXXXXNYIGHF 466
+ P LS + ++ LL ++P R DG H
Sbjct: 629 --VKFPRDVLSQEGRSFVKGLLNRNPKHRLGA----IDDG-------------RELRAHP 669
Query: 467 IFRKIIWKQLLSGDLQKISVGPILPIITDWELAENFDTEFTEKRLDTSIYDNGIEINNPR 526
F I W+ L QK P P + NFD EFT TS + + P
Sbjct: 670 FFADIDWEAL----KQKKIPPPFKPHLVSETDTSNFDPEFT--TASTSYMNK----HQPM 719
Query: 527 ATKESAFAGSTDYFKGFSYVASRSYLERH 555
T F GF++V S ++ H
Sbjct: 720 MTATPLSPAMQAKFAGFTFV-DESAIDEH 747
>CE20493 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1370
Score = 155 bits (393), Expect = 1e-37
Identities = 92/287 (32%), Positives = 145/287 (50%), Gaps = 20/287 (6%)
Query: 156 SSFSKTGAPRVLDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEK 215
S++ +T DDF IR + GAYG +A+K++ K +++
Sbjct: 344 SAWQETNRAPCEDDFDTIRLVSNGAYGAVYLVRHRETRQRFALKKMNKQTLML------- 396
Query: 216 DANTTVEKRIERTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQ 275
++++ FAER IL+ ++P +V + SF L ++++Y+ GG+ LK
Sbjct: 397 ------RNQVDQVFAERDILTMADNPFVVSFYGSFETRQYLCMLMEYVEGGDCAALLKSA 450
Query: 276 GTLDEGTVAFYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDD 335
GTL V Y AE A+++LHS GIV+RDLKP+N L+ GH+ LTDFGLSK + +
Sbjct: 451 GTLPVELVRLYVAETILAIEYLHSYGIVHRDLKPDNLLITAMGHIKLTDFGLSKIGLMNR 510
Query: 336 AATPEEGENV------NQLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKP 389
EG + Q + GTPEY APE++ Y + DW++LG ++Y+ L+G
Sbjct: 511 TTLVAEGYDAVVETQQFQDKQLCGTPEYIAPEVILRRGYGKPVDWWALGIILYEFLVGIV 570
Query: 390 PFTGVNHKIILNK-IKQEKTGARIPSYLSDGFKDYLGALLRKDPTKR 435
PF G + + +K I ++ L D LL K+P +R
Sbjct: 571 PFFGETPEALFSKVISEDVEYPEEDEALPPEAADLCRRLLEKNPAER 617
>CE13844 [D] KOG0608 Warts/lats-like serine threonine kinases
Length = 908
Score = 155 bits (393), Expect = 1e-37
Identities = 87/265 (32%), Positives = 140/265 (52%), Gaps = 49/265 (18%)
Query: 170 FVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIERTF 229
F I +G GA+G YAMK L+KA++++ + + A
Sbjct: 502 FTVISHIGVGAFGKVSLVRKNDTRKVYAMKSLEKADVIMKQQAAHVKA------------ 549
Query: 230 AERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAAE 289
ER IL++ + P IV+LF+SF D+ LY +++Y+PGG++ L ++G +E FY AE
Sbjct: 550 -ERDILAEADSPWIVRLFFSFQDDACLYFIMEYVPGGDMMTLLIQKGIFEEDLARFYIAE 608
Query: 290 LSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGL----------------SKKSVF 333
L+CA++++H+ G ++RDLKP+N L+++ GH+ LTDFGL +
Sbjct: 609 LACAIEYVHNVGFIHRDLKPDNILIDQHGHIKLTDFGLCTGLRWTHDRRYYGPENDHHRV 668
Query: 334 DDAATPEEGE---------NVNQ------LYSIIGTPEYCAPEILAGEPYTQNCDWYSLG 378
D + P E NV Q +S++GT Y APE++A + Q+CDW+S G
Sbjct: 669 DSFSLPPEVAAIDKSVKVLNVRQQTRRITAHSLVGTGNYMAPEVIAKTGHNQSCDWWSTG 728
Query: 379 CLVYDMLIGKPPF-----TGVNHKI 398
++Y+M+ G+ PF G H+I
Sbjct: 729 VILYEMVFGRVPFHDDTPGGTQHRI 753
>CE05274 [T] KOG0690 Serine/threonine protein kinase
Length = 546
Score = 155 bits (393), Expect = 1e-37
Identities = 93/275 (33%), Positives = 142/275 (50%), Gaps = 32/275 (11%)
Query: 167 LDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIE 226
++DF ++ LG+G +G YA+K LKK I+ E+ +
Sbjct: 190 MEDFDFLKVLGKGTFGKVILCKEKRTQKLYAIKILKKDVIIAREE-------------VA 236
Query: 227 RTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLD-----EG 281
T E +L + +HP + +L YSF N +L V+++ GG+L+YHL + ++ E
Sbjct: 237 HTLTENRVLQRCKHPFLTELKYSFQTNDRLCFVMEFAIGGDLYYHLNREVQMNKEGFSEP 296
Query: 282 TVAFYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSV-FDDAATPE 340
FY +E+ AL +LH+ IVYRDLK EN LL++ GH+ + DFGL K+ + F D +
Sbjct: 297 RARFYGSEIVLALGYLHANSIVYRDLKLENLLLDKDGHIKIADFGLCKEEISFGDKTS-- 354
Query: 341 EGENVNQLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIIL 400
+ GTPEY APE+L Y + DW+ +G ++Y+M+ G+ PF +H +
Sbjct: 355 ---------TFCGTPEYLAPEVLDDHDYGRCVDWWGVGVVMYEMMCGRLPFYSKDHNKLF 405
Query: 401 NKIKQEKTGARIPSYLSDGFKDYLGALLRKDPTKR 435
I R PS LS + L LL KDPT+R
Sbjct: 406 ELIM--AGDLRFPSKLSQEARTLLTGLLVKDPTQR 438
>SPAC17G8.14c [T] KOG0694 Serine/threonine protein kinase
Length = 896
Score = 155 bits (391), Expect = 2e-37
Identities = 112/366 (30%), Positives = 172/366 (46%), Gaps = 44/366 (12%)
Query: 143 SVSSVEETRQLRASSFSKTGAPRV-LDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQL 201
S+SS ++ + S + RV LDDF + LG+G +G YA+K L
Sbjct: 544 SLSSSKDANRSVPESPRREKKNRVTLDDFTFLAVLGKGNFGKVMLAEYKVNKKFYAIKVL 603
Query: 202 KKAEILISEDSIEKDANTTVEKRIERTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQ 261
KK IL +E+ + EK + + ++ +HP ++ LF SF + ++Y V++
Sbjct: 604 KKEAILKNEEL----ESLKTEKHVFE------VANKEKHPFLLNLFASFQTSTRVYFVME 653
Query: 262 YIPGGELFYHLKEQGTLDEGTVAFYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLV 321
YI GG+L H++ Q FY AE+ ALK+ H GI YRDLK +N LL GH+
Sbjct: 654 YILGGDLMVHIQRQ-QFSVKRARFYGAEVCLALKYFHENGIAYRDLKLDNILLCPDGHIR 712
Query: 322 LTDFGLSKKSVFDDAATPEEGENVNQLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLV 381
+ D+GL K+++ T + GTPE+ APEIL + Y+++ DW++ G L+
Sbjct: 713 IADYGLCKENMLLGNTTS----------TFCGTPEFMAPEILLEQQYSKDVDWWAFGVLM 762
Query: 382 YDMLIGKPPFTGVNHKIILNKIKQEKTGARIPSYLSDGFKDYLGALLRKDPTKRWDVDKY 441
Y ML+G+ PF G + + I + I ++ P + L LL +DP +R
Sbjct: 763 YQMLLGQSPFKGEDEEEIFDAILSDE--PLFPINMPADAVSLLRGLLTRDPNQR------ 814
Query: 442 WAQDGPXXXXXXXXXXXXXNYIGHFIFRKIIWKQLLSGDLQKISVGPILPIITDWELAEN 501
GP + H F I+W L + K+ P+I D N
Sbjct: 815 -LGSGP---------KDANEVMAHPFFASIVWDDLYN----KLYEPSYKPLINDPRDLNN 860
Query: 502 FDTEFT 507
FD EFT
Sbjct: 861 FDEEFT 866
>At3g10540 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 483
Score = 155 bits (391), Expect = 2e-37
Identities = 92/293 (31%), Positives = 141/293 (47%), Gaps = 15/293 (5%)
Query: 143 SVSSVEETRQLRASSFSKTGAPRVLDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLK 202
S S+ E + ++ +F DF + G G+Y YA+K +
Sbjct: 15 SSSNGETISRSKSFAFKAPQENFTYHDFELGKIYGVGSYSKVVRAKKKDNGTVYALKIMD 74
Query: 203 KAEILISEDSIEKDANTTVEKRIERTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQY 262
K I T E + ER +L QLEHP IVKLF++F D LY+ L+
Sbjct: 75 KKFI-------------TKENKTAYVKLERIVLDQLEHPGIVKLFFTFQDTQSLYMALES 121
Query: 263 IPGGELFYHLKEQGTLDEGTVAFYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVL 322
GGELF + +G L E FY+AE+ AL+++H+ G+++RD+KPEN LL GH+ +
Sbjct: 122 CEGGELFDQITRKGRLSEDEARFYSAEVVDALEYIHNMGLIHRDIKPENLLLTLDGHIKI 181
Query: 323 TDFGLSKKSVFDDAATPEEGENVNQLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVY 382
DFG K + ++ + +GT Y PE+L P T D ++LGC +Y
Sbjct: 182 ADFGSVKPMQDSQITVLPNAASDDKACTFVGTAAYVPPEVLNSSPATFGNDLWALGCTLY 241
Query: 383 DMLIGKPPFTGVNHKIILNKIKQEKTGARIPSYLSDGFKDYLGALLRKDPTKR 435
ML G PF + +I +I + P++ S+ +D + LL DP++R
Sbjct: 242 QMLSGTSPFKDASEWLIFQRIIAR--DIKFPNHFSEAARDLIDRLLDTDPSRR 292
>SPAC821.12 [R] KOG0605 NDR and related serine/threonine kinases
Length = 469
Score = 154 bits (390), Expect = 3e-37
Identities = 100/323 (30%), Positives = 152/323 (46%), Gaps = 52/323 (16%)
Query: 145 SSVEETRQLRASSFSKTGAPRV------LDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAM 198
S + RQLRAS ++ R L+DF I+ +G+GA+G YAM
Sbjct: 62 SEERKNRQLRASGEKESQFLRFRRTRLSLEDFSTIKVIGKGAFGEVRLVQKLDTGKIYAM 121
Query: 199 KQLKKAEILISEDSIEKDANTTVEKRIERTFAERTILSQLEHPNIVKLFYSFHDNHKLYL 258
K L K E+ + ++ AER +L + + P +V L+Y+F D+ LYL
Sbjct: 122 KSLLKTEMFKRD-------------QLAHVKAERDLLVESDSPWVVSLYYAFQDSLYLYL 168
Query: 259 VLQYIPGGELFYHLKEQGTLDEGTVAFYAAELSCALKFLHSKGIVYRDLKPENCLLNERG 318
+++++PGG+L L T E FY AE A+ +H G ++RD+KP+N L++ G
Sbjct: 169 IMEFLPGGDLMTMLINYDTFSEDVTRFYMAECVLAIADVHRMGYIHRDIKPDNILIDRDG 228
Query: 319 HLVLTDFGLSKKSVFDDAAT----PEEGENVNQ--------------------------- 347
H+ L+DFGLS D + P G V +
Sbjct: 229 HIKLSDFGLSTGFYKQDQSASYMKPRTGNTVKRGQMVDAIWLTMSSKDKMATWKKNRRVM 288
Query: 348 LYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQEK 407
YS +GTP+Y APEI + Y Q+CDW+SLG ++++ LIG PPF N KI +
Sbjct: 289 AYSTVGTPDYIAPEIFLQQGYGQDCDWWSLGAIMFECLIGWPPFCSENSHETYRKIINWR 348
Query: 408 TGARIPS--YLSDGFKDYLGALL 428
P+ +LS +D + L+
Sbjct: 349 ETLTFPNDIHLSIEARDLMDRLM 371
>Hs5453974 [T] KOG0694 Serine/threonine protein kinase
Length = 984
Score = 154 bits (390), Expect = 3e-37
Identities = 110/378 (29%), Positives = 174/378 (45%), Gaps = 52/378 (13%)
Query: 133 DSDKETRDVLSVSSVEETRQLRASSFSKTGAPRVLDDFVPIRCLGEGAYGXXXXXXXXXX 192
D+ + + + +E+ R + F+ L DF LG G +G
Sbjct: 627 DTPQSGLEYSGIQELEDRRSQQRFQFN-------LQDFRCCAVLGRGHFGKVLLAEYKNT 679
Query: 193 XXXYAMKQLKKAEILISEDSIEKDANTTVEKRIERTFAERTILSQLEHPNIVKLFYSFHD 252
+A+K LKK +I ++ D ++ + EKRI T ++ + HP +V LF F
Sbjct: 680 NEMFAIKALKKGDI-VARDEVD---SLMCEKRIFET------VNSVRHPFLVNLFACFQT 729
Query: 253 NHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAAELSCALKFLHSKGIVYRDLKPENC 312
+ V++Y GG+L H+ E FYAA + L++LH IVYRDLK +N
Sbjct: 730 KEHVCFVMEYAAGGDLMMHIHTD-VFSEPRAVFYAACVVLGLQYLHEHKIVYRDLKLDNL 788
Query: 313 LLNERGHLVLTDFGLSKKSV-FDDAATPEEGENVNQLYSIIGTPEYCAPEILAGEPYTQN 371
LL+ G + + DFGL K+ + + D + + GTPE+ APE+L YT+
Sbjct: 789 LLDTEGFVKIADFGLCKEGMGYGDRTS-----------TFCGTPEFLAPEVLTETSYTRA 837
Query: 372 CDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQEKTGARIPSYLSDGFKDYLGALLRKD 431
DW+ LG L+Y+ML+G+ PF G + + + + I ++ R P +LS + LLR++
Sbjct: 838 VDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDE--VRYPRFLSTEAISIMRRLLRRN 895
Query: 432 PTKRWDVDKYWAQDGPXXXXXXXXXXXXXNYIGHFIFRKIIWKQLLSGDLQKISVGPILP 491
P +R + A+D H FR I W L+ ++ P +P
Sbjct: 896 PERRLGASEKDAEDVKK----------------HPFFRLIDWSALMDKKVKP----PFIP 935
Query: 492 IITDWELAENFDTEFTEK 509
I E NFD EFT +
Sbjct: 936 TIRGREDVSNFDDEFTSE 953
>Hs18959200 [D] KOG0608 Warts/lats-like serine threonine kinases
Length = 1088
Score = 154 bits (389), Expect = 3e-37
Identities = 88/259 (33%), Positives = 133/259 (50%), Gaps = 50/259 (19%)
Query: 170 FVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIERTF 229
FV I+ LG GA+G YAMK L+K ++L + N V +
Sbjct: 668 FVKIKTLGIGAFGEVCLACKVDTHALYAMKTLRKKDVL--------NRNQVVHVK----- 714
Query: 230 AERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAAE 289
AER IL++ ++ +VKL+YSF D LY V+ YIPGG++ L E FY AE
Sbjct: 715 AERDILAEADNEWVVKLYYSFQDKDSLYFVMDYIPGGDMMSLLIRMEVFPEHLARFYIAE 774
Query: 290 LSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGL---------------------- 327
L+ A++ +H G ++RD+KP+N L++ GH+ LTDFGL
Sbjct: 775 LTLAIESVHKMGFIHRDIKPDNILIDLDGHIKLTDFGLCTGFRWTHNSKYYQKGSHVRQD 834
Query: 328 --SKKSVFDDAATPEEGENVNQL-------------YSIIGTPEYCAPEILAGEPYTQNC 372
++DD + G+ + L +S++GTP Y APE+L + YTQ C
Sbjct: 835 SMEPSDLWDDVSNCRCGDRLKTLEQRARKQHQRCLAHSLVGTPNYIAPEVLLRKGYTQLC 894
Query: 373 DWYSLGCLVYDMLIGKPPF 391
DW+S+G ++++ML+G+PPF
Sbjct: 895 DWWSVGVILFEMLVGQPPF 913
>At5g04510 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 488
Score = 154 bits (389), Expect = 3e-37
Identities = 95/306 (31%), Positives = 148/306 (48%), Gaps = 19/306 (6%)
Query: 133 DSDKETRDVLSVSSVEETRQLRASSFSKTGAPR---VLDDFVPIRCLGEGAYGXXXXXXX 189
+ + +++ VL +S R+ SFS AP+ DF + G G+Y
Sbjct: 2 EKEFDSKLVLQGNSSNGANVSRSKSFSFK-APQENFTSHDFEFGKIYGVGSYSKVVRAKK 60
Query: 190 XXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIERTFAERTILSQLEHPNIVKLFYS 249
YA+K + K I T E + ER +L QLEHP I+KL+++
Sbjct: 61 KETGTVYALKIMDKKFI-------------TKENKTAYVKLERIVLDQLEHPGIIKLYFT 107
Query: 250 FHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAAELSCALKFLHSKGIVYRDLKP 309
F D LY+ L+ GGELF + +G L E FY AE+ AL+++HS G+++RD+KP
Sbjct: 108 FQDTSSLYMALESCEGGELFDQITRKGRLSEDEARFYTAEVVDALEYIHSMGLIHRDIKP 167
Query: 310 ENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVNQLYSIIGTPEYCAPEILAGEPYT 369
EN LL GH+ + DFG K + ++ + +GT Y PE+L P T
Sbjct: 168 ENLLLTSDGHIKIADFGSVKPMQDSQITVLPNAASDDKACTFVGTAAYVPPEVLNSSPAT 227
Query: 370 QNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQEKTGARIPSYLSDGFKDYLGALLR 429
D ++LGC +Y ML G PF + +I +I + P++ S+ +D + LL
Sbjct: 228 FGNDLWALGCTLYQMLSGTSPFKDASEWLIFQRIIAR--DIKFPNHFSEAARDLIDRLLD 285
Query: 430 KDPTKR 435
+P++R
Sbjct: 286 TEPSRR 291
>CE05507 [T] KOG0603 Ribosomal protein S6 kinase
Length = 785
Score = 154 bits (388), Expect = 4e-37
Identities = 105/280 (37%), Positives = 149/280 (52%), Gaps = 35/280 (12%)
Query: 167 LDDFVPIRCLGEGAYGXXXXXXXXXXX---XXYAMKQLKKAEILISEDSIEKDANTTVEK 223
+++F +R LG+GAYG YAMK L+K +L T +K
Sbjct: 14 MENFALLRVLGKGAYGKVFLVRKVGGKDHNTIYAMKVLRKTRVL------------TKQK 61
Query: 224 RIERTFAERTILSQLEH-PNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGT 282
+E T AER +L +L P +V LFY+F + KL++V++Y+ GGELF HL +G D
Sbjct: 62 TLEHTMAERQVLERLRGTPFLVNLFYAFQTDTKLHIVMEYVRGGELFTHLCSRGHFDLEA 121
Query: 283 VAFYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEG 342
F AEL A+ LH + ++YRDLK EN LL+E GH+ LTDFGLSK + P E
Sbjct: 122 ARFVIAELVVAIDSLHQRKVIYRDLKLENILLDEEGHVKLTDFGLSKLFL------PGEL 175
Query: 343 ENVNQLYSIIGTPEYCAPEILAGEP---YTQNCDWYSLGCLVYDMLIGKPPFT--GVNH- 396
+ N S GT EY +PE++ P Y+ DW+SLG + +++L G PFT G +
Sbjct: 176 DRAN---SYCGTIEYMSPEVI-NRPEGGYSDVVDWWSLGVISFELLTGCSPFTVDGAQNS 231
Query: 397 -KIILNKIKQEKTGARIPSYLSDGFKDYLGALLRKDPTKR 435
K I +I +K P + +D++G LL K KR
Sbjct: 232 SKDIAKRIMTKK--VPFPKTMDVDARDFIGQLLEKKLEKR 269
Score = 91.7 bits (226), Expect = 3e-18
Identities = 71/240 (29%), Positives = 112/240 (46%), Gaps = 28/240 (11%)
Query: 231 ERTILSQLE-HPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAAE 289
E IL ++ HPNIV+L D YLV++ + G EL +++ E A +
Sbjct: 424 EARILEMVQGHPNIVQLHDVHSDPLHFYLVMEILTGNELLERIRKLERFTESEAADIMRQ 483
Query: 290 LSCALKFLHSKGIVYRDLKPENCL---LNERGHLVLTDFGLSKKSVFDDAATPEEGENVN 346
L A+K+LH K IV+RDLKPEN L ++ L L DFG ++ + + +
Sbjct: 484 LVSAVKYLHDKRIVHRDLKPENILFESIDSSARLRLVDFGFARLLPNSMEQQLKSVQVLR 543
Query: 347 QLYSIIG------------TPEYCAPEIL----AGEPYTQNCDWYSLGCLVYDMLIGKPP 390
++Y +I T +Y APE+L + Y + CD +SLG +++ ML G+ P
Sbjct: 544 KMYGLIAHNHSLHSETPCFTLQYAAPEVLDVGDSQPEYNEQCDLWSLGVVLFTMLSGQVP 603
Query: 391 FTGVNHKIILNKIKQEKTGARIPSYLSDGF-------KDYLGALLRKDPTKRWDVDKYWA 443
F + + +I Q A S+ D + K+ + LL DP KR + + A
Sbjct: 604 FHARSRQESATEIMQRICRAEF-SFTGDAWTNVSADAKNLITGLLTVDPKKRLSMQELTA 662
>At2g19400 [R] KOG0605 NDR and related serine/threonine kinases
Length = 545
Score = 154 bits (388), Expect = 4e-37
Identities = 99/320 (30%), Positives = 155/320 (47%), Gaps = 59/320 (18%)
Query: 134 SDKETRDVLSVSSVEETRQLRASSFSKTGAPRV-LDDFVPIRCLGEGAYGXXXXXXXXXX 192
S+KE ++L E Q + + +++ R+ +DDF + +G GA+G
Sbjct: 74 SEKEQLELL------EDLQRKETEYTRLMRNRLCVDDFDLLSIIGRGAFGEVRLCREKKT 127
Query: 193 XXXYAMKQLKKAEILISEDSIEKDANTTVEKRIERTFAERTILSQLEHPNIVKLFYSFHD 252
YAMK+LKK+E+L ++E AER +L+++ IVKL+YSF D
Sbjct: 128 GNIYAMKKLKKSEMLS-------------RGQVEHVRAERNLLAEVASDCIVKLYYSFQD 174
Query: 253 NHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAAELSCALKFLHSKGIVYRDLKPENC 312
LYL+++Y+ GG++ L + TL E FY A+ A++ +H V+RD+KP+N
Sbjct: 175 PEYLYLIMEYLSGGDVMTLLMREETLTETVARFYIAQSVLAIESIHKHNYVHRDIKPDNL 234
Query: 313 LLNERGHLVLTDFGLSKKSVFDDAAT-----PEEGENVNQ-------------------- 347
LL++ GH+ L+DFGL K + + P EN+N+
Sbjct: 235 LLDKYGHMKLSDFGLCKPLDCRNISAMNVNEPLNDENINESIDGDENCSIGRRGRRWKSP 294
Query: 348 --------------LYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTG 393
YS +GTP+Y APE+L + Y CDW+SLG ++Y+ML+G PPF
Sbjct: 295 LEQLQHWQINRRKLAYSTVGTPDYIAPEVLLKKGYGVECDWWSLGAIMYEMLVGYPPFYS 354
Query: 394 VNHKIILNKIKQEKTGARIP 413
+ KI +T P
Sbjct: 355 DDPVTTCRKIVSWRTHLVFP 374
>7301971 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 356
Score = 153 bits (387), Expect = 6e-37
Identities = 88/270 (32%), Positives = 139/270 (50%), Gaps = 26/270 (9%)
Query: 167 LDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIE 226
LDD+ LG G++G YA KQL K +I+ + K++
Sbjct: 44 LDDYEIKATLGSGSFGKVQLVRERESGVYYASKQLSKDQIVKT-------------KQVS 90
Query: 227 RTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFY 286
+E+ +L + PN V L S+ D LYLVL I GGELF + ++ E FY
Sbjct: 91 HVMSEKNVLRSMTFPNTVNLIASYKDFDSLYLVLPLIGGGELFTYHRKVRKFTEKQARFY 150
Query: 287 AAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVN 346
AA++ AL++LH ++YRDLKPEN ++++ G+L +TDFG +KK
Sbjct: 151 AAQVFLALEYLHHCSLLYRDLKPENIMMDKNGYLKVTDFGFAKKV-------------ET 197
Query: 347 QLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQE 406
+ ++ GTPEY PEI+ +PY + DW++ G LV++ + G PF+ N ++ K
Sbjct: 198 RTMTLCGTPEYLPPEIIQSKPYGTSVDWWAFGVLVFEFVAGHSPFSAHNRDVMSMYNKIC 257
Query: 407 KTGARIPSYLSDGFKDYLGALLRKDPTKRW 436
+ ++PSY S + + LL+ D +KR+
Sbjct: 258 EADYKMPSYFSGALRHLVDHLLQVDLSKRF 287
>7294265 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 2139
Score = 153 bits (387), Expect = 6e-37
Identities = 108/361 (29%), Positives = 172/361 (46%), Gaps = 48/361 (13%)
Query: 168 DDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIER 227
+DF ++ + GAYG +AMK++ K +++ ++E+
Sbjct: 833 NDFDIVKLISNGAYGAVYLVKHKTTRQRFAMKKINKNNLIL-------------RNQVEQ 879
Query: 228 TFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYA 287
FAER ILS ++P +V ++ SF L LV++Y+ GG+ LK G L FY
Sbjct: 880 VFAERDILSFADNPFVVSMYCSFETKKHLCLVMEYVEGGDCGTLLKNIGPLPADMARFYF 939
Query: 288 AELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEG--ENV 345
AE A+++LHS GIV+RDLKP+N L+ GH+ LTDFGLSK + A EG ++
Sbjct: 940 AETVLAVEYLHSYGIVHRDLKPDNLLITALGHIKLTDFGLSKMGLMSLATNLYEGYIDSE 999
Query: 346 NQLYS---IIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTG-VNHKIILN 401
+ +S + GTPEY APE++ + Y + DW+S+G ++Y+ LIG PF G ++ +
Sbjct: 1000 TRQFSDKQVYGTPEYIAPEVILRQGYGKPVDWWSMGIILYEFLIGCVPFFGETTEELFAH 1059
Query: 402 KIKQEKTGARIPSY-LSDGFKDYLGALLRKDPTKRWDVDKYWAQDGPXXXXXXXXXXXXX 460
+ + + + KD + LL+++P D+ Q G
Sbjct: 1060 TVNDDIEWPDSEDWPVQAEAKDIISQLLQQNPR-----DRLGTQSGALEMKE-------- 1106
Query: 461 NYIGHFIFRKIIWKQLLSGDLQKISVGPILPIITDWELAENFDTEFTEKRLDTSIYDNGI 520
H F + W LL QK P +L+ + DT + + R+D +D G
Sbjct: 1107 ----HEYFLGMDWNSLLR---QKAEFVP--------QLSHDDDTSYFDTRMDRYNHDLGG 1151
Query: 521 E 521
E
Sbjct: 1152 E 1152
>SPCC417.06c [R] KOG0605 NDR and related serine/threonine kinases
Length = 624
Score = 153 bits (386), Expect = 8e-37
Identities = 107/399 (26%), Positives = 176/399 (43%), Gaps = 57/399 (14%)
Query: 176 LGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIERTFAERTIL 235
LG+G YG AMK +KK+ + + ++ ER IL
Sbjct: 168 LGQGGYGSVWLAKKRNTHELLAMKMMKKSTLQQLNE-------------VKHILNERDIL 214
Query: 236 SQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAAELSCALK 295
+ +VKL+Y+F D K+YL ++Y+PGG+ L +G L E FY AE+ A+
Sbjct: 215 TNTNSEWLVKLYYAFQDKEKVYLAMEYVPGGDFRTFLTTKGLLHENQTRFYLAEMVAAIS 274
Query: 296 FLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDD-----------AATPEE--- 341
+H G ++RDLKPEN L++++GH+ L+DFGLS V + A P+
Sbjct: 275 AVHKLGYMHRDLKPENFLIDQKGHIKLSDFGLSTAIVTSNQVNRLQHALVSAVNPQRPYL 334
Query: 342 -------------GENVNQLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGK 388
+N N++ S++G+PEY APE++ G+ Y + D++SLGC+ Y+ L+G
Sbjct: 335 TQKQRRNIYKALLEKNENKVNSVVGSPEYMAPEVVYGKKYDRTVDYWSLGCICYECLVGY 394
Query: 389 PPFTGVNHKIILNKIKQEKTGARIPSYLSDGFKDYLGALLRKDPTKRWDVDKYWAQDGPX 448
PPF+G + + + + PS +G D R D+ W+
Sbjct: 395 PPFSGSTLQETWTNLYYWREMLQRPSKNENGI---------YDKKARSVSDEAWSFITKC 445
Query: 449 XXXXXXXXXXXXNYIGHFIFRKIIWKQLLSGDLQKISVGPILPIITDWELAENFDTEFTE 508
H F+++ W L+K +V P +P + + FD E
Sbjct: 446 LTEPTSRFQSTIEIQKHPFFKRLHW-----NGLRKRAVPPFVPRLENQLDTSYFDDFNDE 500
Query: 509 KRLDT--SIYDNGIEINNPRATKESAFAGSTDYFKGFSY 545
+ LD +Y+ + +A G+ F GF++
Sbjct: 501 QVLDAYKDVYEKQRKAEQ-KAKSNGVMNGNQRQFLGFTF 538
>CE02604 [T] KOG0695 Serine/threonine protein kinase
Length = 597
Score = 153 bits (386), Expect = 8e-37
Identities = 121/403 (30%), Positives = 186/403 (46%), Gaps = 66/403 (16%)
Query: 145 SSVEETRQLRASSFSKTGAPRVLDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKA 204
+S + +R + + SK L+DF + +G G+Y YA+K +KK
Sbjct: 230 TSHDASRAMNGNGSSKWAVS--LNDFRLLTVIGRGSYAKVVQAEHVSTRQIYAIKIIKKE 287
Query: 205 EILISEDSIEKDANTTVEKRIERTFAERTILSQLE-HPNIVKLFYSFHDNHKLYLVLQYI 263
ED I+ E+++ +P +V L F +L+ V++++
Sbjct: 288 MFNEDED-------------IDWVQTEKSVFEAASNYPFLVGLHSCFQTESRLFFVIEFV 334
Query: 264 PGGELFYHLKEQGTLDEGTVAFYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLT 323
PGG+L +H+++Q L E FY+ E+ AL FLHS+GI+YRDLK +N L++ GH+ LT
Sbjct: 335 PGGDLMFHMQQQRKLPEEHARFYSGEIILALHFLHSRGIIYRDLKLDNVLIDAEGHIKLT 394
Query: 324 DFGLSKKSVFDDAATPEEGENVNQLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYD 383
D+G+ K+++ D T + GTP Y APEIL G+ Y + DW++LG L+++
Sbjct: 395 DYGMCKENIKDGDLTS----------TFCGTPNYIAPEILRGDEYGFSVDWWALGVLMFE 444
Query: 384 MLIGKPPFTGV-------NHKIILNKIKQEKTGARIPSYLSDGFKDYLGALLRKDPTKRW 436
M+ G+ PF V N + L +I E+ RIP LS L L KDPT+R
Sbjct: 445 MMAGRSPFDIVGMQNSEENTEDYLFQIILERQ-IRIPRSLSVRASGILKGFLNKDPTERL 503
Query: 437 DVDKYWAQDGPXXXXXXXXXXXXXNYIGHFIFRKII-WKQLLSGDLQKISVGPILPIITD 495
K +G + H FR I W+ L QK P P +
Sbjct: 504 GC-KLDINEG------------LRDMKEHQFFRGFIDWEAL----EQKAVAPPYHPAVES 546
Query: 496 WELAENFDTEFTEK-------------RLDTSIYDNGIEINNP 525
+FD +FT++ R+D S +D G E NP
Sbjct: 547 DRDLTHFDHQFTDELPQLSPDNPDVIARIDQSEFD-GFEYVNP 588
>SPAC4G8.05 [R] KOG0610 Putative serine/threonine protein kinase
Length = 566
Score = 152 bits (384), Expect = 1e-36
Identities = 107/321 (33%), Positives = 155/321 (47%), Gaps = 44/321 (13%)
Query: 144 VSSVEETRQLRASSFSKTGAPRVLD------DFVPIRCLGEGAYGXXXXXXXXXXXXXYA 197
++ +++T RA ++S ++ D F + LG+G G YA
Sbjct: 164 LAHIKKTVATRARTYSSNSI-KICDVEVGPSSFEKVFLLGKGDVGRVYLVREKKSGKFYA 222
Query: 198 MKQLKKAEILISEDSIEKDANTTVEKRIERTFAERTILSQLEHPNIVKLFYSFHDNHKLY 257
MK L K E++ S +R FAE+ IL+ HP IV L++SF + LY
Sbjct: 223 MKVLSKQEMIKRNKS-------------KRAFAEQHILATSNHPFIVTLYHSFQSDEYLY 269
Query: 258 LVLQYIPGGELFYHLKEQG--TLDEGTVAFYAAELSCALKFLHSKGIVYRDLKPENCLLN 315
L ++Y GGE F L+ + L E FY AE++ AL++LH G +YRDLKPEN LL+
Sbjct: 270 LCMEYCMGGEFFRALQRRPGRCLSENEAKFYIAEVTAALEYLHLMGFIYRDLKPENILLH 329
Query: 316 ERGHLVLTDFGLSKKSVFDDAATPEEGENVN-----------------QLYSIIGTPEYC 358
E GH++L+DF LSK+S A T + N + S +GT EY
Sbjct: 330 ESGHIMLSDFDLSKQSNSAGAPTVIQARNAPSAQNAYALDTKSCIADFRTNSFVGTEEYI 389
Query: 359 APEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQEKT----GARIPS 414
APE++ G +T DW++LG L Y+ML PF G N + + I + A PS
Sbjct: 390 APEVIKGCGHTSAVDWWTLGILFYEMLYATTPFKGKNRNMTFSNILHKDVIFPEYADAPS 449
Query: 415 YLSDGFKDYLGALLRKDPTKR 435
+S K+ + LL KD R
Sbjct: 450 -ISSLCKNLIRKLLVKDENDR 469
>Hs5453978 [T] KOG0614 cGMP-dependent protein kinase
Length = 762
Score = 152 bits (384), Expect = 1e-36
Identities = 90/263 (34%), Positives = 144/263 (54%), Gaps = 24/263 (9%)
Query: 173 IRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIERTFAER 232
I LG G +G +AMK ++K I+ + K+ E ++E+
Sbjct: 456 IATLGVGGFGRVELVKVKNENVAFAMKCIRKKHIVDT-------------KQQEHVYSEK 502
Query: 233 TILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAAELSC 292
IL +L P IVKL+ +F DN +Y++L+ GGEL+ L+++G+ DE T F A ++
Sbjct: 503 RILEELCSPFIVKLYRTFKDNKYVYMLLEACLGGELWSILRDRGSFDEPTSKFCVACVTE 562
Query: 293 ALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVNQLYSII 352
A +LH GI+YRDLKPEN +L+ G+L L DFG +KK + + ++
Sbjct: 563 AFDYLHRLGIIYRDLKPENLILDAEGYLKLVDFGFAKKI-----------GSGQKTWTFC 611
Query: 353 GTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQEKTGARI 412
GTPEY APE++ + + + D++SLG LVY++L G PPF+GV+ + N I +
Sbjct: 612 GTPEYVAPEVILNKGHDFSVDFWSLGILVYELLTGNPPFSGVDQMMTYNLILKGIEKMDF 671
Query: 413 PSYLSDGFKDYLGALLRKDPTKR 435
P ++ +D + L R++PT+R
Sbjct: 672 PRKITRRPEDLIRRLCRQNPTER 694
>7301980 [D] KOG0608 Warts/lats-like serine threonine kinases
Length = 1105
Score = 151 bits (382), Expect = 2e-36
Identities = 88/256 (34%), Positives = 134/256 (51%), Gaps = 47/256 (18%)
Query: 170 FVPIRCLGEGAYGXXXXXXXXXXXXX-YAMKQLKKAEILISEDSIEKDANTTVEKRIERT 228
FV ++ +G GA+G YAMK L+KA++L ++
Sbjct: 719 FVKLKPIGVGAFGEVTLVSKIDTSNHLYAMKTLRKADVL-------------KRNQVAHV 765
Query: 229 FAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAA 288
AER IL++ ++ +VKL+YSF D LY V+ YIPGG+L L + G +E FY A
Sbjct: 766 KAERDILAEADNNWVVKLYYSFQDKDNLYFVMDYIPGGDLMSLLIKLGIFEEELARFYIA 825
Query: 289 ELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGL------SKKSVF--------- 333
E++CA+ +H G ++RD+KP+N L++ GH+ LTDFGL + S +
Sbjct: 826 EVTCAVDSVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHNSKYYQENGNHSR 885
Query: 334 DDAATPEEGENVN------------------QLYSIIGTPEYCAPEILAGEPYTQNCDWY 375
D+ P E + N +S++GTP Y APE+L YTQ CD++
Sbjct: 886 QDSMEPWEEYSENGPKPTVLERRRMRDHQRVLAHSLVGTPNYIAPEVLERSGYTQLCDYW 945
Query: 376 SLGCLVYDMLIGKPPF 391
S+G ++Y+ML+G+PPF
Sbjct: 946 SVGVILYEMLVGQPPF 961
>Hs4506735 [T] KOG0603 Ribosomal protein S6 kinase
Length = 772
Score = 150 bits (380), Expect = 4e-36
Identities = 126/405 (31%), Positives = 182/405 (44%), Gaps = 63/405 (15%)
Query: 152 QLRASSFSKTGAPRVL--DDFVPIRCLGEGAYGXXXXXXXXXXXXX---YAMKQLKKAEI 206
+LR + + TG + ++F ++ LG GAYG YAMK L+KA +
Sbjct: 13 ELRITEANLTGHEEKVSVENFELLKVLGTGAYGKVFLVRKAGGHDAGKLYAMKVLRKAAL 72
Query: 207 LISEDSIEKDANTTVEKRIERTFAERTILSQLEH-PNIVKLFYSFHDNHKLYLVLQYIPG 265
+ K E T ER++L + P +V L Y+F + KL+L+L Y+ G
Sbjct: 73 VQRA------------KTQEHTRTERSVLELVRQAPFLVTLHYAFQTDAKLHLILDYVSG 120
Query: 266 GELFYHLKEQGTLDEGTVAFYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDF 325
GE+F HL ++ E V Y E+ AL+ LH GI+YRDLK EN LL+ GH+VLTDF
Sbjct: 121 GEMFTHLYQRQYFKEAEVRVYGGEIVLALEHLHKLGIIYRDLKLENVLLDSEGHIVLTDF 180
Query: 326 GLSKKSVFDDAATPEEGENVNQLYSIIGTPEYCAPEILAGEP-YTQNCDWYSLGCLVYDM 384
GLSK+ + E + +S GT EY APEI+ + + + DW+SLG L++++
Sbjct: 181 GLSKEFL---------TEEKERTFSFCGTIEYMAPEIIRSKTGHGKAVDWWSLGILLFEL 231
Query: 385 LIGKPPFTGVNHKIILNKIKQE--KTGARIPSYLSDGFKDYLGALLRKDPTKRWDVDKYW 442
L G PFT + ++ + K P + +D L LL KDP KR
Sbjct: 232 LTGASPFTLEGERNTQAEVSRRILKCSPPFPPRIGPVAQDLLQRLLCKDPKKRLGAGPQG 291
Query: 443 AQDGPXXXXXXXXXXXXXNYIGHFIFRKIIWKQLLSGDLQKISVGPILPIITDWELAENF 502
AQ+ H F+ + W L + + P P I NF
Sbjct: 292 AQE----------------VRNHPFFQGLDWVALAARKIP----APFRPQIRSELDVGNF 331
Query: 503 DTEFTEKRLDTSIYDNGIEINNPRATKESAFAGSTDYFKGFSYVA 547
EFT RL+ G S G F+G+S+VA
Sbjct: 332 AEEFT--RLEPVYSPPG-----------SPPPGDPRIFQGYSFVA 363
Score = 99.8 bits (247), Expect = 1e-20
Identities = 69/224 (30%), Positives = 112/224 (49%), Gaps = 26/224 (11%)
Query: 240 HPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAAELSCALKFLHS 299
HPN+V L HD YLVL+ + GGEL H++++ E + L A+ F+H
Sbjct: 463 HPNVVNLHEVHHDQLHTYLVLELLRGGELLEHIRKKRHFSESEASQILRSLVSAVSFMHE 522
Query: 300 K-GIVYRDLKPENCLLNER---GHLVLTDFGLSKKSVFDDAATPEEGENVNQLYSIIGTP 355
+ G+V+RDLKPEN L + + + DFG ++ + + T
Sbjct: 523 EAGVVHRDLKPENILYADDTPGAPVKIIDFGFARLRPQSPGVP---------MQTPCFTL 573
Query: 356 EYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHK-------IILNKIKQEKT 408
+Y APE+LA + Y ++CD +SLG ++Y ML G+ PF G + + I+ KI++ +
Sbjct: 574 QYAAPELLAQQGYDESCDLWSLGVILYMMLSGQVPFQGASGQGGQSQAAEIMCKIREGRF 633
Query: 409 GARIPSY--LSDGFKDYLGALLRKDPTKRWDVD----KYWAQDG 446
++ +S+ K+ + LL DP KR ++ W QDG
Sbjct: 634 SLDGEAWQGVSEEAKELVRGLLTVDPAKRLKLEGLRGSSWLQDG 677
>Hs14149671 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1734
Score = 149 bits (377), Expect = 8e-36
Identities = 88/274 (32%), Positives = 136/274 (49%), Gaps = 19/274 (6%)
Query: 168 DDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIER 227
+DF I+ + GAYG +AMK++ K +++ +I++
Sbjct: 510 EDFETIKLISNGAYGAVFLVRHKSTRQRFAMKKINKQNLIL-------------RNQIQQ 556
Query: 228 TFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYA 287
F ER IL+ E+P +V +F SF L +V++Y+ GG+ LK G L V Y
Sbjct: 557 AFVERDILTFAENPFVVSMFCSFDTKRHLCMVMEYVEGGDCATLLKNIGALPVDMVRLYF 616
Query: 288 AELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVNQ 347
AE AL++LH+ GIV+RDLKP+N L+ GH+ LTDFGLSK + EG
Sbjct: 617 AETVLALEYLHNYGIVHRDLKPDNLLITSMGHIKLTDFGLSKMGLMSLTTNLYEGHIEKD 676
Query: 348 L-----YSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNK 402
+ GTPEY APE++ + Y + DW+++G ++Y+ L+G PF G + + +
Sbjct: 677 AREFLDKQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQ 736
Query: 403 -IKQEKTGARIPSYLSDGFKDYLGALLRKDPTKR 435
I E L +D LL ++P +R
Sbjct: 737 VISDEIVWPEGDEALPPDAQDLTSKLLHQNPLER 770
>YBL105c [T] KOG0694 Serine/threonine protein kinase
Length = 1151
Score = 149 bits (376), Expect = 1e-35
Identities = 89/272 (32%), Positives = 140/272 (50%), Gaps = 29/272 (10%)
Query: 167 LDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIE 226
LD+FV ++ LG+G +G A+K LKK I+ + D IE
Sbjct: 821 LDNFVLLKVLGKGNFGKVILSKSKNTDRLCAIKVLKKDNIIQNHD-------------IE 867
Query: 227 RTFAERTIL---SQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTV 283
AE+ + ++ +HP + L+ SF +++Y +++I GG+L +H++ Q L
Sbjct: 868 SARAEKKVFLLATKTKHPFLTNLYCSFQTENRIYFAMEFIGGGDLMWHVQNQ-RLSVRRA 926
Query: 284 AFYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGE 343
FYAAE+ ALK+ H G++YRDLK EN LL GH+ + D+GL K ++
Sbjct: 927 KFYAAEVLLALKYFHDNGVIYRDLKLENILLTPEGHIKIADYGLCKDEMWYG-------- 978
Query: 344 NVNQLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKI 403
N+ + GTPE+ APEIL + YT+ DW++ G L+Y ML+ + PF+G + + N I
Sbjct: 979 --NRTSTFCGTPEFMAPEILKEQEYTKAVDWWAFGVLLYQMLLCQSPFSGDDEDEVFNAI 1036
Query: 404 KQEKTGARIPSYLSDGFKDYLGALLRKDPTKR 435
++ P ++ LL KDP KR
Sbjct: 1037 LTDE--PLYPIDMAGEIVQIFQGLLTKDPEKR 1066
>Hs4506073 [T] KOG0694 Serine/threonine protein kinase
Length = 942
Score = 148 bits (374), Expect = 2e-35
Identities = 119/417 (28%), Positives = 188/417 (44%), Gaps = 66/417 (15%)
Query: 92 DSGESKQSQTKEPARRRSSLYNKFVVNPAQHTIRLSLNAQGDSDKETRDVLSVSSVEETR 151
DS S Q +++P SSL + P Q + L + ET++ + R
Sbjct: 558 DSDSSPQKSSRDPPSSPSSLSS-----PIQESTAPELPS------ETQETPGPALCSPLR 606
Query: 152 QLRASSFSKTGAPRVLDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISED 211
+ +P L+DF + LG G +G +A+K LKK +I ++ D
Sbjct: 607 K----------SPLTLEDFKFLAVLGRGHFGKVLLSEFRPSGELFAIKALKKGDI-VARD 655
Query: 212 SIEKDANTTVEKRIERTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYH 271
+E + EKRI ++ HP +V LF F + V++Y GG+L H
Sbjct: 656 EVE---SLMCEKRI------LAAVTSAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLMLH 706
Query: 272 LKEQGTLDEGTVAFYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKS 331
+ E FY+A + L+FLH IVYRDLK +N LL+ G++ + DFGL K+
Sbjct: 707 IHSD-VFSEPRAIFYSACVVLGLQFLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEG 765
Query: 332 V-FDDAATPEEGENVNQLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPP 390
+ + D + + GTPE+ APE+L YT+ DW+ LG L+Y+ML+G+ P
Sbjct: 766 MGYGDRTS-----------TFCGTPEFLAPEVLTDTSYTRAVDWWGLGVLLYEMLVGESP 814
Query: 391 FTGVNHKIILNKIKQEKTGARIPSYLSDGFKDYLGALLRKDPTKRWDVDKYWAQDGPXXX 450
F G + + + + I ++ R P +LS + LLR++P +R + A+D
Sbjct: 815 FPGDDEEEVFDSIVNDE--VRYPRFLSAEAIGIMRRLLRRNPERRLGSSERDAEDVKKQP 872
Query: 451 XXXXXXXXXXNYIGHFIFRKIIWKQLLSGDLQKISVGPILPIITDWELAENFDTEFT 507
FR + W+ LL+ L P +P ++ NFD EFT
Sbjct: 873 ----------------FFRTLGWEALLARRLPP----PFVPTLSGRTDVSNFDEEFT 909
>Hs14758219 [T] KOG0694 Serine/threonine protein kinase
Length = 942
Score = 148 bits (374), Expect = 2e-35
Identities = 119/417 (28%), Positives = 188/417 (44%), Gaps = 66/417 (15%)
Query: 92 DSGESKQSQTKEPARRRSSLYNKFVVNPAQHTIRLSLNAQGDSDKETRDVLSVSSVEETR 151
DS S Q +++P SSL + P Q + L + ET++ + R
Sbjct: 558 DSDSSPQKSSRDPPSSPSSLSS-----PIQESTAPELPS------ETQETPGPALCSPLR 606
Query: 152 QLRASSFSKTGAPRVLDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISED 211
+ +P L+DF + LG G +G +A+K LKK +I ++ D
Sbjct: 607 K----------SPLTLEDFKFLAVLGRGHFGKVLLSEFRPSGELFAIKALKKGDI-VARD 655
Query: 212 SIEKDANTTVEKRIERTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYH 271
+E + EKRI ++ HP +V LF F + V++Y GG+L H
Sbjct: 656 EVE---SLMCEKRI------LAAVTSAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLMLH 706
Query: 272 LKEQGTLDEGTVAFYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKS 331
+ E FY+A + L+FLH IVYRDLK +N LL+ G++ + DFGL K+
Sbjct: 707 IHSD-VFSEPRAIFYSACVVLGLQFLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEG 765
Query: 332 V-FDDAATPEEGENVNQLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPP 390
+ + D + + GTPE+ APE+L YT+ DW+ LG L+Y+ML+G+ P
Sbjct: 766 MGYGDRTS-----------TFCGTPEFLAPEVLTDTSYTRAVDWWGLGVLLYEMLVGESP 814
Query: 391 FTGVNHKIILNKIKQEKTGARIPSYLSDGFKDYLGALLRKDPTKRWDVDKYWAQDGPXXX 450
F G + + + + I ++ R P +LS + LLR++P +R + A+D
Sbjct: 815 FPGDDEEEVFDSIVNDE--VRYPRFLSAEAIGIMRRLLRRNPERRLGSSERDAEDVKKQP 872
Query: 451 XXXXXXXXXXNYIGHFIFRKIIWKQLLSGDLQKISVGPILPIITDWELAENFDTEFT 507
FR + W+ LL+ L P +P ++ NFD EFT
Sbjct: 873 ----------------FFRTLGWEALLARRLPP----PFVPTLSGRTDVSNFDEEFT 909
>Hs20543401 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 2092
Score = 147 bits (371), Expect = 4e-35
Identities = 116/395 (29%), Positives = 176/395 (44%), Gaps = 62/395 (15%)
Query: 143 SVSSVEETRQLRASSFSKTGAPRVLDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLK 202
SVSS + +LR PR DF I+ + GAYG +AMK++
Sbjct: 20 SVSSSNASLKLRRK-------PRE-SDFETIKLISNGAYGAVYFVRHKESRQRFAMKKIN 71
Query: 203 KAEILISEDSIEKDANTTVEKRIERTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQY 262
K +++ +I++ F ER IL+ E+P +V ++ SF L +V++Y
Sbjct: 72 KQNLIL-------------RNQIQQAFVERDILTFAENPFVVSMYCSFETRRHLCMVMEY 118
Query: 263 IPGGELFYHLKEQGTLDEGTVAFYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVL 322
+ GG+ +K G L Y AE AL++LH+ GIV+RDLKP+N L+ GH+ L
Sbjct: 119 VEGGDCATLMKNMGPLPVDMARMYFAETVLALEYLHNYGIVHRDLKPDNLLVTSMGHIKL 178
Query: 323 TDFGLSKKSVFDDAATPEEGENVNQL-----YSIIGTPEYCAPEILAGEPYTQNCDWYSL 377
TDFGLSK + EG + GTPEY APE++ + Y + DW+++
Sbjct: 179 TDFGLSKVGLMSMTTNLYEGHIEKDAREFLDKQVCGTPEYIAPEVILRQGYGKPVDWWAM 238
Query: 378 GCLVYDMLIGKPPFTG-----VNHKIILNKIK-QEKTGARIPSYLSDGFKDYLGALLRKD 431
G ++Y+ L+G PF G + ++I ++I EK A P +D + LLR++
Sbjct: 239 GIILYEFLVGCVPFFGDTPEELFGQVISDEINWPEKDEAPPPD-----AQDLITLLLRQN 293
Query: 432 PTKRWDVDKYWAQDGPXXXXXXXXXXXXXNYIGHFIFRKIIWKQLLSGDLQKISVGPILP 491
P +R H FR + W LL QK P L
Sbjct: 294 PLER------------------LGTGGAYEVKQHRFFRSLDWNSLLR---QKAEFIPQLE 332
Query: 492 IITDWEL----AENFDTEFTEKRLDTSIYDNGIEI 522
D +E + TE+ DT+ D +EI
Sbjct: 333 SEDDTSYFDTRSEKYHHMETEEEDDTNDEDFNVEI 367
>Hs17455844 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1139
Score = 147 bits (371), Expect = 4e-35
Identities = 88/273 (32%), Positives = 135/273 (49%), Gaps = 19/273 (6%)
Query: 169 DFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIERT 228
DF I+ + GAYG +A+K++ K +++ +I++
Sbjct: 196 DFETIKLISNGAYGAVYLVRHRDTRQRFAIKKINKQNLIL-------------RNQIQQV 242
Query: 229 FAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAA 288
F ER IL+ E+P +V +F SF L +V++Y+ GG+ LK G L Y A
Sbjct: 243 FVERDILTFAENPFVVSMFCSFETRRHLCMVMEYVEGGDCATLLKNMGPLPVDMARLYFA 302
Query: 289 ELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVNQL 348
E AL++LH+ GIV+RDLKP+N L+ GH+ LTDFGLSK + A EG
Sbjct: 303 ETVLALEYLHNYGIVHRDLKPDNLLITSLGHIKLTDFGLSKIGLMSMATNLYEGHIEKDA 362
Query: 349 YSII-----GTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNK- 402
I GTPEY APE++ + Y + DW+++G ++Y+ L+G PF G + + +
Sbjct: 363 REFIDKQVCGTPEYIAPEVIFRQGYGKPVDWWAMGVVLYEFLVGCVPFFGDTPEELFGQV 422
Query: 403 IKQEKTGARIPSYLSDGFKDYLGALLRKDPTKR 435
+ E L +D + LLR+ P R
Sbjct: 423 VSDEIMWPEGDEALPADAQDLITRLLRQSPLDR 455
>SPBC1861.09 [R] KOG0610 Putative serine/threonine protein kinase
Length = 526
Score = 147 bits (370), Expect = 5e-35
Identities = 97/290 (33%), Positives = 139/290 (47%), Gaps = 39/290 (13%)
Query: 170 FVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIERTF 229
F IR LG+G G +AMK L K E++ ++ R
Sbjct: 155 FEKIRLLGQGDVGKVYLVRQKSNHRLFAMKILNKREMI-------------KRHKVNRVL 201
Query: 230 AERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELF--YHLKEQGTLDEGTVAFYA 287
AE+ IL++ +HP IV L++SF LYL ++Y GGE F H + L E FYA
Sbjct: 202 AEQEILTKSKHPFIVTLYHSFQSRDYLYLCMEYCAGGEFFRALHSLPKHILPEKDACFYA 261
Query: 288 AELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLS--------------KKSVF 333
AE++ AL++LH G +YRDLKPEN LL++ GH++L+DF LS K S F
Sbjct: 262 AEVTAALEYLHLMGFIYRDLKPENILLHQSGHIMLSDFDLSKPISIVTHPTVVLPKHSTF 321
Query: 334 DDAATPEEGENVNQLY---SIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPP 390
+ + + S +GT EY APE++ +T DW++LG +Y++L G P
Sbjct: 322 SQEKPALDTNSYFSNFRTNSFVGTEEYIAPEVIRSCGHTVAVDWWTLGIFIYEILYGTTP 381
Query: 391 FTGVNHKIILNKIKQEKTGARIPSY-----LSDGFKDYLGALLRKDPTKR 435
F G N + I + P Y +S K + LL KD +KR
Sbjct: 382 FKGKNRHATFSNILY--SDVSFPEYHGAPNVSSTCKSLIRRLLVKDESKR 429
>At2g45490 [D] KOG0580 Serine/threonine protein kinase
Length = 288
Score = 147 bits (370), Expect = 5e-35
Identities = 93/274 (33%), Positives = 141/274 (50%), Gaps = 26/274 (9%)
Query: 167 LDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIE 226
L DF R LG+G +G A+K +I ++ IEK + ++
Sbjct: 19 LADFEIGRPLGKGKFGRVYLAREAKSKYIVALK-------VIFKEQIEK---YKIHHQLR 68
Query: 227 RTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFY 286
R E I + L HPNI++LF FHDN +++L+L+Y GGEL+ LK+ G L E A Y
Sbjct: 69 R---EMEIQTSLRHPNILRLFGWFHDNERIFLILEYAHGGELYGVLKQNGHLTEQQAATY 125
Query: 287 AAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVN 346
A LS AL + H K +++RD+KPEN LL+ G L + DFG S +S N
Sbjct: 126 IASLSQALAYCHGKCVIHRDIKPENLLLDHEGRLKIADFGWSVQS-------------SN 172
Query: 347 QLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQE 406
+ ++ GT +Y APE++ + D ++LG L Y+ L G PPF + K +I +
Sbjct: 173 KRKTMCGTLDYLAPEMVENRDHDYAVDNWTLGILCYEFLYGNPPFEAESQKDTFKRILKI 232
Query: 407 KTGARIPSYLSDGFKDYLGALLRKDPTKRWDVDK 440
+ +S+ K+ + LL KDP+KR ++K
Sbjct: 233 DLSFPLTPNVSEEAKNLISQLLVKDPSKRLSIEK 266
>Hs7019489 [T] KOG0694 Serine/threonine protein kinase
Length = 889
Score = 146 bits (369), Expect = 7e-35
Identities = 110/362 (30%), Positives = 165/362 (45%), Gaps = 51/362 (14%)
Query: 150 TRQLRASSFSKTGAPRVLDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILIS 209
TR+ + S T P L DF + LG G +G YA+K LKK E+L
Sbjct: 539 TRRGPSPPASPTRKPPRLQDFRCLAVLGRGHFGKVLLVQFKGTGKYYAIKALKKQEVLSR 598
Query: 210 EDSIEKDANTTVEKRIERTFAERTILSQLE---HPNIVKLFYSFHDNHKLYLVLQYIPGG 266
++ IE + E+ IL + HP ++ L F + V +++PGG
Sbjct: 599 DE-------------IESLYCEKRILEAVGCTGHPFLLSLLVCFQTSSHARFVTEFVPGG 645
Query: 267 ELFYHLKEQGTLDEGTVAFYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFG 326
+L + E E FY A + L+FLH K I+YRDLK +N LL+ +G L + DFG
Sbjct: 646 DLMMQIHED-VFPEPQARFYVACVVLGLQFLHEKKIIYRDLKLDNLLLDAQGFLKIADFG 704
Query: 327 LSKKSV-FDDAATPEEGENVNQLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDML 385
L K+ + F D + + GTPE+ APE+L E YTQ DW++LG L+Y+ML
Sbjct: 705 LCKEGIGFGDRTS-----------TFCGTPEFLAPEVLTQEAYTQAVDWWALGVLLYEML 753
Query: 386 IGKPPFTGVNHKIILNKIKQEKTGARIPSYLSDGFKDYLGALLRKDPTKRWDVDKYWAQD 445
+G+ PF G + + + I A P +LS +++ LL+K P KR + A++
Sbjct: 754 VGECPFPGDTEEEVFDCI--VNMDAPYPGFLSVQGLEFIQKLLQKCPEKRLGAGEQDAEE 811
Query: 446 GPXXXXXXXXXXXXXNYIGHFIFRKIIWKQLLSGDLQKISVGPILPIITDWELAENFDTE 505
FR W+ LL+ +Q P +P + F+ E
Sbjct: 812 IKVQP----------------FFRTTNWQALLARTIQP----PFVPTLCGPADLRYFEGE 851
Query: 506 FT 507
FT
Sbjct: 852 FT 853
>Hs4885583 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1354
Score = 146 bits (369), Expect = 7e-35
Identities = 112/391 (28%), Positives = 179/391 (45%), Gaps = 64/391 (16%)
Query: 168 DDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIER 227
+D+ ++ +G GA+G YAMK L K E++ DS
Sbjct: 74 EDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAF------------- 120
Query: 228 TFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYA 287
+ ER I++ P +V+LFY+F D+ LY+V++Y+PGG+L +L + E FY
Sbjct: 121 FWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLV-NLMSNYDVPEKWARFYT 179
Query: 288 AELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVNQ 347
AE+ AL +HS G ++RD+KP+N LL++ GHL L DFG K E + +
Sbjct: 180 AEVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKM---------NKEGMVR 230
Query: 348 LYSIIGTPEYCAPEILAGEP----YTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKI 403
+ +GTP+Y +PE+L + Y + CDW+S+G +Y+ML+G PF + +KI
Sbjct: 231 CDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKI 290
Query: 404 KQEKTGARIP--SYLSDGFKDYLGALLRKDPTKRWDVDKYWAQDGPXXXXXXXXXXXXXN 461
K P + +S K+ + A L D + ++G
Sbjct: 291 MNHKNSLTFPDDNDISKEAKNLICAFLT-------DREVRLGRNGVEEIKR--------- 334
Query: 462 YIGHFIFRKIIWKQLLSGDLQKISVGPILPIITDWELAENFDTEFTEKRLDTSIYDNGIE 521
H F+ W + + + +V P++P +L+ + DT D D G E
Sbjct: 335 ---HLFFKNDQW----AWETLRDTVAPVVP-----DLSSDIDT----SNFDDLEEDKGEE 378
Query: 522 INNPRATKESAFAGSTDYFKGFSYVASRSYL 552
P AF G+ F GF+Y ++R YL
Sbjct: 379 ETFP---IPKAFVGNQLPFVGFTYYSNRRYL 406
>YNL161w [R] KOG0605 NDR and related serine/threonine kinases
Length = 756
Score = 146 bits (368), Expect = 9e-35
Identities = 107/369 (28%), Positives = 166/369 (43%), Gaps = 71/369 (19%)
Query: 114 KFVVNPAQHTIRLSLNAQGDSDKETRDVLSVSSVEETRQLRASSFSKTGAPRV-LDDFVP 172
K+ + + + L + E R +SS+ + + S F + R+ L+DF
Sbjct: 299 KYAIERNERRVELETELTSHNWSEERKSRQLSSLGK----KESQFLRLRRTRLSLEDFHT 354
Query: 173 IRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIERTFAER 232
++ +G+GA+G YAMK L K+E+ +KD V+ AER
Sbjct: 355 VKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMY------KKDQLAHVK-------AER 401
Query: 233 TILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAAELSC 292
+L+ + P +V L+YSF D LYL+++++PGG+L L E FY AE
Sbjct: 402 DVLAGSDSPWVVSLYYSFQDAQYLYLIMEFLPGGDLMTMLIRWQLFTEDVTRFYMAECIL 461
Query: 293 ALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLS------------KKSVFDDAATPE 340
A++ +H G ++RD+KP+N L++ RGH+ L+DFGLS KK + D AT
Sbjct: 462 AIETIHKLGFIHRDIKPDNILIDIRGHIKLSDFGLSTGFHKTHDSNYYKKLLQQDEATNG 521
Query: 341 EGE----NVN-----------------------------------QLYSIIGTPEYCAPE 361
+ N N YS +GTP+Y APE
Sbjct: 522 ISKPGTYNANTTDTANKRQTMVVDSISLTMSNRQQIQTWRKSRRLMAYSTVGTPDYIAPE 581
Query: 362 ILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQEKTGARIPS--YLSDG 419
I + Y Q CDW+SLG ++Y+ LIG PPF + KI + + P ++S
Sbjct: 582 IFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQFPDDIHISYE 641
Query: 420 FKDYLGALL 428
+D + LL
Sbjct: 642 AEDLIRRLL 650
>SPCC320.12c [D] KOG0580 Serine/threonine protein kinase
Length = 384
Score = 145 bits (366), Expect = 2e-34
Identities = 102/350 (29%), Positives = 175/350 (49%), Gaps = 37/350 (10%)
Query: 96 SKQSQTKEPARRRSSLYNKFVVNPAQHTIRLSLNAQGDSDKETRDVLSVSSVEETRQLRA 155
S S T P R++ + V+ + +SL A G +K T + SS+ + + A
Sbjct: 45 STPSTTANPGRQQLL---RLAVSNQRQVNNVSL-ANGKENKRTSNSKFNSSLRKIEEPIA 100
Query: 156 SSFSKTGAPRVLDDFVPI----RCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISED 211
S G P+ + + + + LG+G +G A+K L K+E++ S+
Sbjct: 101 GVPSSAG-PQWREFHIGMFEIGKPLGKGKFGRVYLAKEKKTGFIVALKTLHKSELVQSK- 158
Query: 212 SIEKDANTTVEKRIERTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYH 271
+EK++ R E I S L H NI++L+ FHD ++YL+L++ GEL+ H
Sbjct: 159 ---------IEKQVRR---EIEIQSNLRHKNILRLYGHFHDEKRIYLILEFAGRGELYQH 206
Query: 272 LKEQGTLDEGTVAFYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKS 331
L+ E + Y +++ AL +LH K +++RD+KPEN LL G + L+DFG S +
Sbjct: 207 LRRAKRFSEEVASKYIFQMANALSYLHKKHVIHRDIKPENILLGIDGEIKLSDFGWSVHA 266
Query: 332 VFDDAATPEEGENVNQLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPF 391
N+ ++ GT +Y PE++ G+ +T+ D +SLG L Y+ L+G PPF
Sbjct: 267 ------------PSNRRTTLCGTLDYLPPEMVEGKEHTEKVDLWSLGVLTYEFLVGAPPF 314
Query: 392 TGVN-HKIILNKIKQEKTGARIPSYLSDGFKDYLGALLRKDPTKRWDVDK 440
++ H +I K +IPS++ +D + LL+ +P KR +++
Sbjct: 315 EDMSGHSATYKRI--AKVDLKIPSFVPPDARDLISRLLQHNPEKRMSLEQ 362
>Hs4507273 [D] KOG0580 Serine/threonine protein kinase
Length = 275
Score = 145 bits (366), Expect = 2e-34
Identities = 89/269 (33%), Positives = 138/269 (51%), Gaps = 27/269 (10%)
Query: 167 LDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIE 226
+DDF R LG+G +G A+K L K++I EK+ +E ++
Sbjct: 6 VDDFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQI-------EKEG---LEHQLR 55
Query: 227 RTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFY 286
R E I + L+HPNI++L+ FHD ++YL+L+Y P GEL+ L++ LDE A
Sbjct: 56 R---EIEIQAHLQHPNILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATI 112
Query: 287 AAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVN 346
E++ AL + H K +++RD+KPEN LL RG + + DFG S + + T
Sbjct: 113 IEEVADALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFGWSVHTPLPERKT-------- 164
Query: 347 QLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQE 406
+ GT +Y PE++ G Y + D + +G L Y++L+G PPF +H +I
Sbjct: 165 ----MCGTLDYLPPEMIEGRTYDEKVDLWCIGVLCYELLVGYPPFESASHSETYRRIL-- 218
Query: 407 KTGARIPSYLSDGFKDYLGALLRKDPTKR 435
K R P + G +D + LLR P +R
Sbjct: 219 KVDVRFPLSMPLGARDLISRLLRYQPLER 247
>ECU07g0520 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 322
Score = 145 bits (365), Expect = 2e-34
Identities = 94/270 (34%), Positives = 137/270 (49%), Gaps = 28/270 (10%)
Query: 167 LDDFVPIRCLGEGAYGXXXXXXXXXX-XXXYAMKQLKKAEILISEDSIEKDANTTVEKRI 225
+ DF ++ +G GA+G +AMK L EIL + + + ++ KRI
Sbjct: 4 IQDFEFVKVVGVGAFGKVHLVRLKSSPTSVFAMKMLDFGEILRQRLADQLENEISILKRI 63
Query: 226 ERTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAF 285
P + KL+ + K+ L+++Y+ GGELFY LK+ G DE F
Sbjct: 64 YGC------------PFVAKLYSTDFHGGKVGLIMEYVGGGELFYWLKKCGRFDEQMARF 111
Query: 286 YAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENV 345
YAAE+ AL+F+H +GI+YRDLKPEN L+ GH+ L DFG S E EN+
Sbjct: 112 YAAEIISALRFIHGRGILYRDLKPENILITSTGHIKLIDFGFS----------VYESENI 161
Query: 346 NQLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQ 405
Y I GTPEY +PE L E + D++ LG ++Y+ML G PPF + I +KI +
Sbjct: 162 ---YMISGTPEYMSPEKLRSEDDGRASDYWGLGVMIYEMLCGDPPFYDSSADAIYHKILE 218
Query: 406 EKTGARIPSYLSDGFKDYLGALLRKDPTKR 435
+ P Y+S + + LL K+ R
Sbjct: 219 --SNVVFPHYVSPVARCLITGLLDKNRATR 246
>Hs4507275 [D] KOG0580 Serine/threonine protein kinase
Length = 403
Score = 144 bits (364), Expect = 3e-34
Identities = 87/269 (32%), Positives = 137/269 (50%), Gaps = 27/269 (10%)
Query: 167 LDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIE 226
L+DF R LG+G +G A+K L KA++ VE ++
Sbjct: 130 LEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQL----------EKAGVEHQLR 179
Query: 227 RTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFY 286
R E I S L HPNI++L+ FHD ++YL+L+Y P G ++ L++ DE A Y
Sbjct: 180 R---EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATY 236
Query: 287 AAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVN 346
EL+ AL + HSK +++RD+KPEN LL G L + DFG S + T
Sbjct: 237 ITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTT-------- 288
Query: 347 QLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQE 406
+ GT +Y PE++ G + + D +SLG L Y+ L+GKPPF ++ +I
Sbjct: 289 ----LCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRI--S 342
Query: 407 KTGARIPSYLSDGFKDYLGALLRKDPTKR 435
+ P ++++G +D + LL+ +P++R
Sbjct: 343 RVEFTFPDFVTEGARDLISRLLKHNPSQR 371
>CE18646 [T] KOG0690 Serine/threonine protein kinase
Length = 528
Score = 144 bits (364), Expect = 3e-34
Identities = 116/432 (26%), Positives = 183/432 (41%), Gaps = 55/432 (12%)
Query: 129 NAQGDSDKETRDVLSVSSVEETRQLRASSFSKTGAPR----VLDDFVPIRCLGEGAYGXX 184
N G+SD D S S + + PR +DDF ++ LG+G +G
Sbjct: 136 NPSGESDVNM-DATSTRSDNDFESTVMNIDEPEEVPRKNTVTMDDFDFLKVLGQGTFGKV 194
Query: 185 XXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIERTFAERTILSQLEHPNIV 244
YA+K ++K ++ + + T E +L HP +
Sbjct: 195 ILCREKSSDKLYAIKIIRKEMVVDRSE-------------VAHTLTENRVLYACVHPFLT 241
Query: 245 KLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAAELSCALKFLHSKGIVY 304
L YSF + + V+++ GGELF HL+ T E FY +E+ AL +LH + IVY
Sbjct: 242 LLKYSFQAQYHICFVMEFANGGELFTHLQRCKTFSEARTRFYGSEIILALGYLHHRNIVY 301
Query: 305 RDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVNQLYSIIGTPEYCAPEILA 364
RD+K EN LL+ GH+ +TDFGL K EE + ++ + GTPEY APE++
Sbjct: 302 RDMKLENLLLDRDGHIKITDFGLCK----------EEIKYGDKTSTFCGTPEYLAPEVIE 351
Query: 365 GEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQEKTGARIPSYLSDGFKDYL 424
Y ++ DW+ +G ++Y+M+ G+ PF+ + + I + P+ LS L
Sbjct: 352 DIDYDRSVDWWGVGVVMYEMMCGRLPFSAKENGKLFELI--TTCDLKFPNRLSPEAVTLL 409
Query: 425 GALLRKDPTKRWDVDKYWAQDGPXXXXXXXXXXXXXNYIGHFIFRKIIWKQLLSGDLQKI 484
LL + P KR GP F+ + W+ L +++
Sbjct: 410 SGLLERVPAKRLGA-------GPDDAREVSRAE---------FFKDVDWEATLRKEVEP- 452
Query: 485 SVGPILPIITDWELAENFDTEFTEKRLDTSIYDNGIEINNPRATKESAFAGSTDYFKGFS 544
P P + FD EFT + + G E+ P +E ++ + S
Sbjct: 453 ---PFKPNVMSETDTSFFDREFTSMPVQLTPPRRGEEL--PTVDEEEEL--QANFIQFAS 505
Query: 545 YVASRSYLERHF 556
Y S S LER +
Sbjct: 506 YYVSGS-LERSY 516
>YOL100w [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 1081
Score = 144 bits (363), Expect = 3e-34
Identities = 90/295 (30%), Positives = 149/295 (50%), Gaps = 21/295 (7%)
Query: 145 SSVEETRQLRASSFSKTGAPRVLDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKA 204
SS ++ +S K + + DF +G+GAY YA K L K
Sbjct: 154 SSSQKPIAKESSKAQKNIIKKGIKDFKFGSVIGDGAYSTVMLATSIDTKKRYAAKVLNK- 212
Query: 205 EILISEDSIEKDANTTVEKRIERTFAERTILSQLEH-PNIVKLFYSFHDNHKLYLVLQYI 263
E LI + K+++ E+T L +L + P++V+LF +F D LY +L+Y
Sbjct: 213 EYLIRQ------------KKVKYVSIEKTALQKLNNSPSVVRLFSTFQDESSLYFLLEYA 260
Query: 264 PGGELFYHLKEQGTLDEGTVAFYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLT 323
P G+ +K+ G+LDE +YAA++ A+ +LHS GI++RD+KPEN LL+ + LT
Sbjct: 261 PNGDFLSLMKKYGSLDETCARYYAAQIIDAIDYLHSNGIIHRDIKPENILLDGEMKIKLT 320
Query: 324 DFGLSK-KSVFDDAATPEEGENVNQLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVY 382
DFG +K + +++ + E + + S +GT EY +PE+L CD ++ GC+++
Sbjct: 321 DFGTAKLLNPTNNSVSKPEYDLSTRSKSFVGTAEYVSPELLNDSFTDYRCDIWAFGCILF 380
Query: 383 DMLIGKPPFTGVNHKIILNKIKQEKTGARIPSYLSDGFKDYLGALLRKDPTKRWD 437
M+ GKPPF N + K+ ++ + GF + L++K K D
Sbjct: 381 QMIAGKPPFKATNEYLTFQKV------MKVQYAFTPGFPLIIRDLVKKILVKNLD 429
>Hs4759178 [D] KOG0580 Serine/threonine protein kinase
Length = 344
Score = 144 bits (362), Expect = 5e-34
Identities = 91/283 (32%), Positives = 144/283 (50%), Gaps = 33/283 (11%)
Query: 159 SKTGAPRVL------DDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDS 212
+ +G P +L DDF R LG+G +G A+K L K++I
Sbjct: 60 NSSGTPDILTRHFTIDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQI------ 113
Query: 213 IEKDANTTVEKRIERTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHL 272
EK+ VE ++ R E I + L HPNI++L+ F+D ++YL+L+Y P GEL+ L
Sbjct: 114 -EKEG---VEHQLRR---EIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAPRGELYKEL 166
Query: 273 KEQGTLDEGTVAFYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSV 332
++ T DE A EL+ AL + H K +++RD+KPEN LL +G L + DFG S +
Sbjct: 167 QKSCTFDEQRTATIMEELADALMYCHGKKVIHRDIKPENLLLGLKGELKIADFGWSVHAP 226
Query: 333 FDDAATPEEGENVNQLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFT 392
T + GT +Y PE++ G + + D + +G L Y++L+G PPF
Sbjct: 227 SLRRKT------------MCGTLDYLPPEMIEGRMHNEKVDLWCIGVLCYELLVGNPPFE 274
Query: 393 GVNHKIILNKIKQEKTGARIPSYLSDGFKDYLGALLRKDPTKR 435
+H +I K + P+ + G +D + LLR +P++R
Sbjct: 275 SASHNETYRRI--VKVDLKFPASVPTGAQDLISKLLRHNPSER 315
>Hs10835242 [T] KOG0614 cGMP-dependent protein kinase
Length = 686
Score = 144 bits (362), Expect = 5e-34
Identities = 102/339 (30%), Positives = 158/339 (46%), Gaps = 45/339 (13%)
Query: 167 LDDFVPIRCLGEGAYGXXXXXXXXXXXX-XYAMKQLKKAEILISEDSIEKDANTTVEKRI 225
L DF I LG G +G +AMK LKK I+ +
Sbjct: 372 LSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQ------------- 418
Query: 226 ERTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAF 285
E +E+ I+ IV+L+ +F D+ LY++++ GGEL+ L+++G+ ++ T F
Sbjct: 419 EHIRSEKQIMQGAHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRF 478
Query: 286 YAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENV 345
Y A + A +LHSKGI+YRDLKPEN +L+ RG+ L DFG +KK F
Sbjct: 479 YTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFG----------- 527
Query: 346 NQLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQ 405
+ ++ GTPEY APEI+ + + + D++SLG L+Y++L G PPF+G + N I +
Sbjct: 528 KKTWTFCGTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILR 587
Query: 406 EKTGARIPSYLSDGFKDYLGALLRKDPTKRWDVDKYWAQDGPXXXXXXXXXXXXXNYIGH 465
P ++ + + L R +P++R K +D H
Sbjct: 588 GIDMIEFPKKIAKNAANLIKKLCRDNPSERLGNLKNGVKD----------------IQKH 631
Query: 466 FIFRKIIWKQLLSGDLQKISVGPILPIITDWELAENFDT 504
F W+ L G L PI+P + NFD+
Sbjct: 632 KWFEGFNWEGLRKGTL----TPPIIPSVASPTDTSNFDS 666
>CE24761 [D] KOG0580 Serine/threonine protein kinase
Length = 305
Score = 144 bits (362), Expect = 5e-34
Identities = 92/287 (32%), Positives = 142/287 (49%), Gaps = 31/287 (10%)
Query: 162 GAPRVLDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTV 221
G ++DF R LG+G +G A+K L K++++ + V
Sbjct: 22 GGKFTINDFEIGRPLGKGKFGSVYLARTKTGHFHVAIKVLFKSQLI----------SGGV 71
Query: 222 EKRIERTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEG 281
E ++ER E I S L HPNI+KL+ F D K+YLVL+Y PGGE++ L E
Sbjct: 72 EHQLER---EIEIQSHLNHPNIIKLYTYFWDAKKIYLVLEYAPGGEMYKQLTVSKRFSEP 128
Query: 282 TVAFYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEE 341
T A Y E++ AL + H K +++RD+KPEN L+ +G L + DFG S +
Sbjct: 129 TAAKYMYEIADALSYCHRKNVIHRDIKPENLLIGSQGELKIGDFGWSVHA---------- 178
Query: 342 GENVNQLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILN 401
N+ ++ GT +Y PE++ G ++ D +++G L Y+ L+GKPPF +
Sbjct: 179 --PSNKRQTMCGTMDYLPPEMVNGADHSDAVDLWAIGVLCYEFLVGKPPFEHEDQSKTYA 236
Query: 402 KIKQEKTGARIPSYLSDGFKDYLGALLRKDPTKRWDVDK----YWAQ 444
IK + P + G +D +G LL DP R +++ YW Q
Sbjct: 237 AIKAAR--FTYPDSVKKGARDLIGRLLVVDPKARCTLEQVKEHYWIQ 281
>CE29298 [T] KOG0690 Serine/threonine protein kinase
Length = 483
Score = 143 bits (361), Expect = 6e-34
Identities = 93/311 (29%), Positives = 145/311 (45%), Gaps = 30/311 (9%)
Query: 129 NAQGDSDKETRDVLSVSSVEETRQLRASSFSKTGAPR----VLDDFVPIRCLGEGAYGXX 184
N G+SD D S S + + PR +DDF ++ LG+G +G
Sbjct: 136 NPSGESDVNM-DATSTRSDNDFESTVMNIDEPEEVPRKNTVTMDDFDFLKVLGQGTFGKV 194
Query: 185 XXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIERTFAERTILSQLEHPNIV 244
YA+K ++K ++ + + T E +L HP +
Sbjct: 195 ILCREKSSDKLYAIKIIRKEMVVDRSE-------------VAHTLTENRVLYACVHPFLT 241
Query: 245 KLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAAELSCALKFLHSKGIVY 304
L YSF + + V+++ GGELF HL+ T E FY +E+ AL +LH + IVY
Sbjct: 242 LLKYSFQAQYHICFVMEFANGGELFTHLQRCKTFSEARTRFYGSEIILALGYLHHRNIVY 301
Query: 305 RDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVNQLYSIIGTPEYCAPEILA 364
RD+K EN LL+ GH+ +TDFGL K EE + ++ + GTPEY APE++
Sbjct: 302 RDMKLENLLLDRDGHIKITDFGLCK----------EEIKYGDKTSTFCGTPEYLAPEVIE 351
Query: 365 GEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQEKTGARIPSYLSDGFKDYL 424
Y ++ DW+ +G ++Y+M+ G+ PF+ + + I + P+ LS L
Sbjct: 352 DIDYDRSVDWWGVGVVMYEMMCGRLPFSAKENGKLFELI--TTCDLKFPNRLSPEAVTLL 409
Query: 425 GALLRKDPTKR 435
LL + P KR
Sbjct: 410 SGLLERVPAKR 420
>7301972 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 393
Score = 141 bits (355), Expect = 3e-33
Identities = 82/269 (30%), Positives = 139/269 (51%), Gaps = 26/269 (9%)
Query: 167 LDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIE 226
L++++ LG G++G YA K + K +++ K++
Sbjct: 42 LENYITRAVLGNGSFGTVMLVREKSGKNYYAAKMMSKEDLVRL-------------KQVA 88
Query: 227 RTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFY 286
E+ +L+ P ++ L S LYL+L + GGELF + + +E FY
Sbjct: 89 HVHNEKHVLNAARFPFLIYLVDSTKCFDYLYLILPLVNGGELFSYHRRVRKFNEKHARFY 148
Query: 287 AAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVN 346
AA+++ AL+++H ++YRDLKPEN LL++RG++ +TDFG +K+ D T
Sbjct: 149 AAQVALALEYMHKMHLMYRDLKPENILLDQRGYIKITDFGFTKRV---DGRTS------- 198
Query: 347 QLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQE 406
++ GTPEY APEI+ PY ++ DW++ G LVY+ + G+ PF N +IL K
Sbjct: 199 ---TLCGTPEYLAPEIVQLRPYNKSVDWWAFGILVYEFVAGRSPFAIHNRDVILMYSKIC 255
Query: 407 KTGARIPSYLSDGFKDYLGALLRKDPTKR 435
++PSY + + + +L++ D +KR
Sbjct: 256 ICDYKMPSYFTSQLRSLVESLMQVDTSKR 284
>SPBC4C3.11 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 420
Score = 140 bits (354), Expect = 4e-33
Identities = 95/306 (31%), Positives = 147/306 (47%), Gaps = 37/306 (12%)
Query: 159 SKTGAPRVLDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDAN 218
S G+ + D+V +G+G++ YA+K L K I+
Sbjct: 43 SHIGSIKSPADYVFGDIIGDGSFSKVRRATDKKSWKEYAIKVLDKKYIV----------- 91
Query: 219 TTVEKRIERTFAERTILSQLE-HPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGT 277
E +++ ER + +L P I +LF++F D+ KLY VL+ P GEL ++K+
Sbjct: 92 --KENKVKYVNIERDSMMRLNGFPGISRLFHTFQDDLKLYYVLELAPNGELLQYIKKYRF 149
Query: 278 LDEGTVAFYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAA 337
LDE V FYAAE+ +++++HS GI++RDLKPEN L + H+ +TDFG +K
Sbjct: 150 LDENCVRFYAAEILSSIEYMHSCGIIHRDLKPENILFDGNMHVKITDFGTAKILPPKYVN 209
Query: 338 TPEEGENVNQLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHK 397
+P+ + S +GT EY APE+L+ + +++ D ++ C+VY M++G PPF G N
Sbjct: 210 SPDYTTFPS---SFVGTAEYVAPELLSRQVVSKSSDLWAFACVVYQMIVGSPPFHGSNPN 266
Query: 398 IILNKIKQEKTGARIPSYLSDGFKDYLGALLRKDPTKR----------------WDVDKY 441
I KI + +P L L R P+ R W D
Sbjct: 267 NIFKKIMSLE--YELPKLLPPDIVPLFSHLFRIQPSDRSTTQQIKQFPFFATITW--DNL 322
Query: 442 WAQDGP 447
W QD P
Sbjct: 323 WTQDPP 328
>YDR466w [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 898
Score = 140 bits (353), Expect = 5e-33
Identities = 91/251 (36%), Positives = 128/251 (50%), Gaps = 18/251 (7%)
Query: 161 TGAPRVLDDFVPIRCLGEGAYGXXXXXXXXXX-XXXYAMKQLKKAEILISEDSIEKDANT 219
T R DF+ LG G+Y YA+K K I I E ++
Sbjct: 2 TSRKRSPHDFIFKEELGHGSYSTVFKALDKKSPNKIYAIKVCSKKHI-IKEAKVKY---V 57
Query: 220 TVEKRIERTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLD 279
T+EK +L+Q H I+KL+Y+FHD LY VL + PGGEL L + GT +
Sbjct: 58 TIEKNT------MNLLAQKHHAGIIKLYYTFHDEENLYFVLDFAPGGELLSLLHKMGTFN 111
Query: 280 EGTVAFYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLS---KKSVFDDA 336
+ + A+L AL+F+HS GI++RDLKPEN LL+ G L++TDFG + S+ D+
Sbjct: 112 DIWTRHFTAQLIDALEFIHSHGIIHRDLKPENVLLDRDGRLMITDFGAAATIDPSLSGDS 171
Query: 337 A---TPEEGENVNQ-LYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFT 392
A + G NQ S +GT EY +PE+L D ++LGC++Y + G+PPF
Sbjct: 172 AKFNSDSNGSKDNQNCASFVGTAEYVSPELLLYNQCGYGSDIWALGCMIYQFVQGQPPFR 231
Query: 393 GVNHKIILNKI 403
G N KI
Sbjct: 232 GENELKTFEKI 242
>SPAC24B11.11c [R] KOG0605 NDR and related serine/threonine kinases
Length = 607
Score = 140 bits (353), Expect = 5e-33
Identities = 84/274 (30%), Positives = 131/274 (47%), Gaps = 40/274 (14%)
Query: 169 DFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIERT 228
DF I +G+G YG A+K + K+ + ++ I
Sbjct: 207 DFQTITQVGQGGYGSVWLARKRDTKEIVALKIMNKSVLHKMDE-------------IRHV 253
Query: 229 FAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAA 288
ER IL+ +V+L Y+F D +YL ++++PGG+ L G L + FYA
Sbjct: 254 LTERDILTTANSEWLVRLLYAFQDTSNIYLAMEFVPGGDFRTLLSNSGVLRDHHAKFYAT 313
Query: 289 ELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGL-----SKKSV---------FD 334
E+ A+ LH G ++RDLKPEN L+ GH+ LTDFGL SKK + +
Sbjct: 314 EMFLAIDALHQLGYIHRDLKPENFLVGASGHIKLTDFGLSSGIISKKKIESMKIRLQEVN 373
Query: 335 DAATPEE-------------GENVNQLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLV 381
+ PE ++ +S++G+P+Y APE+L GE Y + D++SLGC++
Sbjct: 374 NVVVPERSMRERRQVFRTLLSQDPVYAHSVVGSPDYMAPEVLRGENYNHSVDYWSLGCIM 433
Query: 382 YDMLIGKPPFTGVNHKIILNKIKQEKTGARIPSY 415
Y+ L G PPF+G N + +K + + P Y
Sbjct: 434 YECLSGFPPFSGSNVNETWSNLKNWRKCFQRPHY 467
>SPCC576.15c [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 592
Score = 140 bits (352), Expect = 7e-33
Identities = 108/382 (28%), Positives = 173/382 (45%), Gaps = 34/382 (8%)
Query: 64 PPNTYEEEALISDTEEQAEMMSGFLVPPDSGES-KQSQTKEPARRRSSLYNKFVVNPAQH 122
P T E +DT+ ++++ D G S K ++ P + S++ +N +
Sbjct: 7 PNETEASEDAENDTQSESDLSF------DHGSSEKLNRASLPKTQNSAIPQSNALNTTPN 60
Query: 123 TIRLSLNAQGDSDKETRDVLSVSSVEETRQLRASSFSKTGAPRVLDDFVPIRCLGEGAYG 182
+Q DS + S+V SS + T + + DF LGEG+Y
Sbjct: 61 ----ESTSQIDSSPKIP-----SAVPHISTPNPSSGASTPNIKRVSDFKFGEILGEGSYS 111
Query: 183 XXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIERTFAERTILSQLEHPN 242
YA+K L K I+ + K+ +EK ILS+ HP
Sbjct: 112 TVLTATENSTKREYAIKVLDKRHIIKEK----KEKYVNIEKEA------LCILSK--HPG 159
Query: 243 IVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAAELSCALKFLHSKGI 302
+KLFY+F D H LY VL GEL ++ + G +E +YAA + ++ ++H +G+
Sbjct: 160 FIKLFYTFQDAHNLYFVLSLARNGELLDYINKLGRFNEICAQYYAALIVDSIDYMHGRGV 219
Query: 303 VYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVNQ----LYSIIGTPEYC 358
++RDLKPEN LL++ +TDFG +K + E+ + ++ S +GT Y
Sbjct: 220 IHRDLKPENILLDDNMRTKITDFGSAKILNSSHGSHEEDTHHADKPQAHSRSFVGTARYV 279
Query: 359 APEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQEKTGARIPSYLSD 418
+PE+L+ + D ++ GC+++ ML GKPPF N + I IP +SD
Sbjct: 280 SPEVLSDKIAGTASDIWAFGCILFQMLAGKPPFVAGNEYLTFQSILH--LSYEIPPDISD 337
Query: 419 GFKDYLGALLRKDPTKRWDVDK 440
D + LL DP R VD+
Sbjct: 338 VASDLIKKLLVLDPKDRLTVDE 359
>7294566 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1252
Score = 139 bits (351), Expect = 9e-33
Identities = 114/417 (27%), Positives = 188/417 (44%), Gaps = 85/417 (20%)
Query: 147 VEETRQLRASSFSKTGAPRVLDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEI 206
+EETR+LR ++ DDF+ +G+G +G YAMK++KK+ +
Sbjct: 100 IEETRKLRVNA----------DDFLIKTLIGQGYFGNVHLVVERQTNDIYAMKKIKKSVV 149
Query: 207 LISEDSIEKDANTTVEKRIERTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGG 266
S+ E+D I+S ++ L Y+F DN LYLV++Y+PGG
Sbjct: 150 TTSQVKEERD-----------------IMSIRNSEWLINLQYAFQDNDNLYLVMEYMPGG 192
Query: 267 ELFYHLKEQGTLDEGTVAFYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFG 326
+L + G DE FY AEL+ AL LH G V+RD+KPEN L++ GH+ L DFG
Sbjct: 193 DLLSLMSRHGPFDEDLARFYLAELTVALHTLHEMGYVHRDIKPENILIDRFGHIKLADFG 252
Query: 327 LSKKSVFDDAATPEEGENVNQLYSIIGTPEYCAPEI--------LAGEPYTQNCDWYSLG 378
+ AA +G ++ S +GTP+Y APE+ L+ + +CD++S+G
Sbjct: 253 -------NAAALDRDGHVLS--LSPVGTPDYIAPELLQTISTYKLSKSMHDVSCDYWSMG 303
Query: 379 CLVYDMLIGKPPFTGVNHKIILNKIK---QEKTGARIPSYLSD-----GFKDYLGALLRK 430
+ Y+++ PF N +KI +E + S+ +D +++ + +L+
Sbjct: 304 IIGYELICETTPFHEDNVHETYSKILSHCEESHLKELISFPADLKVSVNYRNLIESLV-T 362
Query: 431 DPTKRWDVDKYWAQDGPXXXXXXXXXXXXXNYIGHFIFRKIIWKQLLSGDLQKISVGPIL 490
+P+KR ++ H F +I W + S V PI+
Sbjct: 363 NPSKRLSYER---------------------IKNHPFFSEIPWGSIRS------QVPPII 395
Query: 491 PIITDWELAENFDTEFTEK-RLDTSIYDNGIEINNPRATKESAFAGSTDYFKGFSYV 546
P + + NF+ K R + + + N K + F+G F G+S+V
Sbjct: 396 PTVRSDDDTSNFEDGIRHKTRREQGVAKKSLTTN----MKSNDFSGKDLPFIGYSFV 448
>Hs8923754 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 414
Score = 139 bits (350), Expect = 1e-32
Identities = 94/278 (33%), Positives = 137/278 (48%), Gaps = 38/278 (13%)
Query: 168 DDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIER 227
D F +R +G+G++G YAMK + K + IE+D +
Sbjct: 21 DHFQILRAIGKGSFGKVCIVQKRDTKKMYAMKYMNK------QKCIERD-------EVRN 67
Query: 228 TFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYA 287
F E I+ LEHP +V L+YSF D +++V+ + GG+L YHL++ EGTV Y
Sbjct: 68 VFRELQIMQGLEHPFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQNVHFTEGTVKLYI 127
Query: 288 AELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVNQ 347
EL+ AL++L I++RD+KP+N LL+E GH+ +TDF + AT +G +
Sbjct: 128 CELALALEYLQRYHIIHRDIKPDNILLDEHGHVHITDFNI---------ATVVKG--AER 176
Query: 348 LYSIIGTPEYCAPEIL-----AGEPYTQNCDWYSLGCLVYDMLIGKPPF-----TGVNHK 397
S+ GT Y APE+ G Y+ DW+SLG Y++L G P+ T ++
Sbjct: 177 ASSMAGTKPYMAPEVFQVYMDRGPGYSYPVDWWSLGITAYELLRGWRPYEIHSVTPIDE- 235
Query: 398 IILNKIKQEKTGARIPSYLSDGFKDYLGALLRKDPTKR 435
ILN K E+ S G L LL KDP R
Sbjct: 236 -ILNMFKVER--VHYSSTWCKGMVALLRKLLTKDPESR 270
>Hs4759044 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1388
Score = 139 bits (350), Expect = 1e-32
Identities = 81/250 (32%), Positives = 128/250 (50%), Gaps = 27/250 (10%)
Query: 168 DDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIER 227
+D+ ++ +G GA+G YAMK L K E++ DS
Sbjct: 90 EDYDVVKVIGRGAFGEVQLVRHKASQKVYAMKLLSKFEMIKRSDSAF------------- 136
Query: 228 TFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYA 287
+ ER I++ P +V+LFY+F D+ LY+V++Y+PGG+L +L + E FY
Sbjct: 137 FWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLV-NLMSNYDVPEKWAKFYT 195
Query: 288 AELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVNQ 347
AE+ AL +HS G+++RD+KP+N LL++ GHL L DFG K + +
Sbjct: 196 AEVVLALDAIHSMGLIHRDVKPDNMLLDKHGHLKLADFGTCMKM---------DETGMVH 246
Query: 348 LYSIIGTPEYCAPEILAGEP----YTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKI 403
+ +GTP+Y +PE+L + Y + CDW+S+G +Y+ML+G PF + +KI
Sbjct: 247 CDTAVGTPDYISPEVLKSQGGDGFYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKI 306
Query: 404 KQEKTGARIP 413
K P
Sbjct: 307 MDHKNSLCFP 316
>Hs20536595 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1388
Score = 139 bits (350), Expect = 1e-32
Identities = 81/250 (32%), Positives = 128/250 (50%), Gaps = 27/250 (10%)
Query: 168 DDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIER 227
+D+ ++ +G GA+G YAMK L K E++ DS
Sbjct: 90 EDYDVVKVIGRGAFGEVQLVRHKASQKVYAMKLLSKFEMIKRSDSAF------------- 136
Query: 228 TFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYA 287
+ ER I++ P +V+LFY+F D+ LY+V++Y+PGG+L +L + E FY
Sbjct: 137 FWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLV-NLMSNYDVPEKWAKFYT 195
Query: 288 AELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVNQ 347
AE+ AL +HS G+++RD+KP+N LL++ GHL L DFG K + +
Sbjct: 196 AEVVLALDAIHSMGLIHRDVKPDNMLLDKHGHLKLADFGTCMKM---------DETGMVH 246
Query: 348 LYSIIGTPEYCAPEILAGEP----YTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKI 403
+ +GTP+Y +PE+L + Y + CDW+S+G +Y+ML+G PF + +KI
Sbjct: 247 CDTAVGTPDYISPEVLKSQGGDGFYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKI 306
Query: 404 KQEKTGARIP 413
K P
Sbjct: 307 MDHKNSLCFP 316
>Hs4885347 [T] KOG0986 G protein-coupled receptor kinase
Length = 500
Score = 138 bits (348), Expect = 2e-32
Identities = 94/278 (33%), Positives = 134/278 (47%), Gaps = 32/278 (11%)
Query: 164 PRVLDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEK 223
P + F R LG+G +G YA K+L+K I +K
Sbjct: 149 PVTKNTFRHYRVLGKGGFGEVCACQVRATGKMYACKKLQKKRI---------------KK 193
Query: 224 RIERTFA--ERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGT--LD 279
R A E+ IL +++ +V L Y++ L LVL + GG+L +H+ G D
Sbjct: 194 RKGEAMALNEKRILEKVQSRFVVSLAYAYETKDALCLVLTIMNGGDLKFHIYNLGNPGFD 253
Query: 280 EGTVAFYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATP 339
E FYAAEL C L+ L + IVYRDLKPEN LL++RGH+ ++D GL A
Sbjct: 254 EQRAVFYAAELCCGLEDLQRERIVYRDLKPENILLDDRGHIRISDLGL--------ATEI 305
Query: 340 EEGENVNQLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKII 399
EG+ V +GT Y APE++ E YT + DW+ LGCL+Y+M+ G PF K+
Sbjct: 306 PEGQRVR---GRVGTVGYMAPEVVNNEKYTFSPDWWGLGCLIYEMIQGHSPFKKYKEKVK 362
Query: 400 LNKIKQ--EKTGARIPSYLSDGFKDYLGALLRKDPTKR 435
++ Q + S+ K LL K+P+KR
Sbjct: 363 WEEVDQRIKNDTEEYSEKFSEDAKSICRMLLTKNPSKR 400
>7299536 [D] KOG0580 Serine/threonine protein kinase
Length = 411
Score = 138 bits (348), Expect = 2e-32
Identities = 99/314 (31%), Positives = 153/314 (48%), Gaps = 33/314 (10%)
Query: 130 AQGDSDKETRDVLSVSSVEETR-QLRASSFSKTGAPRVLDDFVPIRCLGEGAYGXXXXXX 188
A +S KE S + E+T+ + + KT L++F R LG G +G
Sbjct: 116 ASSESSKELGAASSSAEKEKTKTETQPQKPKKTWE---LNNFDIGRLLGRGKFGNVYLAR 172
Query: 189 XXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIERTFAERTILSQLEHPNIVKLFY 248
A+K L K +I + VE ++ R E I S L HP+I++L+
Sbjct: 173 EKESQFVVALKVLFKRQI----------GESNVEHQVRR---EIEIQSHLRHPHILRLYA 219
Query: 249 SFHDNHKLYLVLQYIPGGELFYHLKEQGT--LDEGTVAFYAAELSCALKFLHSKGIVYRD 306
FHD+ ++YL+L+Y P G LF L+ Q DE A Y L AL +LH + I++RD
Sbjct: 220 YFHDDVRIYLILEYAPQGTLFNALQAQPMKRFDERQSATYIQALCSALLYLHERDIIHRD 279
Query: 307 LKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVNQLYSIIGTPEYCAPEILAGE 366
+KPEN LL +G L + DFG S E + ++ GT +Y PE++ G+
Sbjct: 280 IKPENLLLGHKGVLKIADFGWSVH------------EPNSMRMTLCGTVDYLPPEMVQGK 327
Query: 367 PYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQEKTGARIPSYLSDGFKDYLGA 426
P+T+N D +SLG L +++L+G PF N+ KI K ++P ++S +
Sbjct: 328 PHTKNVDLWSLGVLCFELLVGHAPFYSKNYDETYKKIL--KVDYKLPEHISKAASHLISK 385
Query: 427 LLRKDPTKRWDVDK 440
LL +P R +D+
Sbjct: 386 LLVLNPQHRLPLDQ 399
>YDR490c [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 766
Score = 138 bits (347), Expect = 3e-32
Identities = 98/315 (31%), Positives = 157/315 (49%), Gaps = 38/315 (12%)
Query: 130 AQGDSDKETRDVLSVSSVEETRQLRASSFSKTGAPRVLDDFVPIRCLGEGAYGXXXXXXX 189
A+ + K +DV+ ++ E T+ + K G + DF LG+G+Y
Sbjct: 94 AERGAAKIVKDVVDPATGELTKHV-----VKMG----IKDFKFGEQLGDGSYSSVVLATA 144
Query: 190 XXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIERTFAERTILSQLEHPN-IVKLFY 248
YA+K L K E LI + K+++ E+ L +L I KLF+
Sbjct: 145 RDSGKKYAVKVLSK-EYLIRQ------------KKVKYVTVEKLALQKLNGTKGIFKLFF 191
Query: 249 SFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAAELSCALKFLHSKGIVYRDLK 308
+F D LY +L+Y P G+ +K+ G+L+E +YA+++ A+ LH+ GI++RD+K
Sbjct: 192 TFQDEASLYFLLEYAPHGDFLGLIKKYGSLNETCARYYASQIIDAVDSLHNIGIIHRDIK 251
Query: 309 PENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVNQLY----SIIGTPEYCAPEILA 364
PEN LL++ + LTDFG + K + ++ + +G+ LY S +GT EY +PE+L
Sbjct: 252 PENILLDKNMKVKLTDFG-TAKILPEEPSNTADGKPYFDLYAKSKSFVGTAEYVSPELLN 310
Query: 365 GEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQEKTGARIPSYLSDGF---- 420
CD ++ GC++Y ML GKPPF N + K+ +I + GF
Sbjct: 311 DNYTDSRCDIWAFGCILYQMLAGKPPFKAANEYLTFQKV------MKIQYAFTAGFPQIV 364
Query: 421 KDYLGALLRKDPTKR 435
KD + LL +DP R
Sbjct: 365 KDLVKKLLVRDPNDR 379
>HsM4507279 [D] KOG0580 Serine/threonine protein kinase
Length = 402
Score = 137 bits (345), Expect = 4e-32
Identities = 84/269 (31%), Positives = 135/269 (49%), Gaps = 27/269 (10%)
Query: 167 LDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIE 226
L+DF R LG+G +G A+K L KA++ VE ++
Sbjct: 129 LEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQL----------EKAGVEHQLR 178
Query: 227 RTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFY 286
R E I S L HPNI++L+ FHD ++YL+L+Y P G ++ L++ DE A
Sbjct: 179 R---EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTANL 235
Query: 287 AAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVN 346
++ AL + HSK +++RD+KPEN LL G L + DFG S + T
Sbjct: 236 YNRIANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTT-------- 287
Query: 347 QLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQE 406
+ GT +Y PE++ G + + D +SLG L Y+ L+GKPPF ++ +I
Sbjct: 288 ----LCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRI--S 341
Query: 407 KTGARIPSYLSDGFKDYLGALLRKDPTKR 435
+ P ++++G +D + LL+ +P++R
Sbjct: 342 RVEFTFPDFVTEGARDLISRLLKHNPSQR 370
>Hs4504101 [T] KOG0986 G protein-coupled receptor kinase
Length = 576
Score = 137 bits (345), Expect = 4e-32
Identities = 93/280 (33%), Positives = 136/280 (48%), Gaps = 36/280 (12%)
Query: 164 PRVLDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEK 223
P + F R LG+G +G YA K+L+K I +K
Sbjct: 180 PVTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRI---------------KK 224
Query: 224 RIERTFA--ERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGT--LD 279
R A E+ IL ++ +V L Y++ L LVL + GG+L +H+ G
Sbjct: 225 RKGEAMALNEKQILEKVNSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFP 284
Query: 280 EGTVAFYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATP 339
E FYAAE+ C L+ LH + IVYRDLKPEN LL++ GH+ ++D GL A
Sbjct: 285 EARAVFYAAEICCGLEDLHRERIVYRDLKPENILLDDHGHIRISDLGL--------AVHV 336
Query: 340 EEGENVNQLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKII 399
EG+ + +GT Y APE++ E YT + DW++LGCL+Y+M+ G+ PF KI
Sbjct: 337 PEGQTIK---GRVGTVGYMAPEVVKNERYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIK 393
Query: 400 LNKIKQEKTGARIPSYLSDGF----KDYLGALLRKDPTKR 435
++ E+ +P S+ F + LL KDP +R
Sbjct: 394 REEV--ERLVKEVPEEYSERFSPQARSLCSQLLCKDPAER 431
>Hs14196445 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 476
Score = 136 bits (343), Expect = 7e-32
Identities = 88/276 (31%), Positives = 135/276 (48%), Gaps = 33/276 (11%)
Query: 170 FVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIERTF 229
F+ + LG GA+ +A+K +KK+ + S+E
Sbjct: 23 FIFMEVLGSGAFSEVFLVKQRLTGKLFALKCIKKSPAF-RDSSLEN-------------- 67
Query: 230 AERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAAE 289
E +L +++H NIV L + YLV+Q + GGELF + E+G E + +
Sbjct: 68 -EIAVLKKIKHENIVTLEDIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQ 126
Query: 290 LSCALKFLHSKGIVYRDLKPENCLL---NERGHLVLTDFGLSKKSVFDDAATPEEGENVN 346
+ A+K+LH GIV+RDLKPEN L E +++TDFGLSK E
Sbjct: 127 VLSAVKYLHENGIVHRDLKPENLLYLTPEENSKIMITDFGLSKM------------EQNG 174
Query: 347 QLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQE 406
+ + GTP Y APE+LA +PY++ D +S+G + Y +L G PPF + KIK+
Sbjct: 175 IMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVITYILLCGYPPFYEETESKLFEKIKEG 234
Query: 407 KTGARIPSY--LSDGFKDYLGALLRKDPTKRWDVDK 440
P + +S+ KD++ LL KDP +R+ +K
Sbjct: 235 YYEFESPFWDDISESAKDFICHLLEKDPNERYTCEK 270
>CE21025 [D] KOG0580 Serine/threonine protein kinase
Length = 326
Score = 136 bits (343), Expect = 7e-32
Identities = 91/303 (30%), Positives = 163/303 (53%), Gaps = 32/303 (10%)
Query: 135 DKETRDVLSVSSVEETRQLRASSFSKTGAPRVLDDFVPIRCLGEGAYGXXXXXXXXXXXX 194
D + +V+S++ E++R R ++ + LDDF R LG+G +G
Sbjct: 12 DDQKAEVISLT--EDSRPQRVDQ-AREESCWSLDDFDVGRPLGKGKFGNVFISREKKTKR 68
Query: 195 XYAMKQLKKAEILISEDSIEKDANTTVEKRIERTFAERTILSQLEHPNIVKLFYSFHDNH 254
A+K L K ++L V +++R E I L HPNI+ L+ FHD+
Sbjct: 69 IIALKVLFKTQLL----------QLGVSHQLKR---EIEIQYHLRHPNILTLYGYFHDDK 115
Query: 255 KLYLVLQYIPGGELFYHLKEQG--TLDEGTVAFYAAELSCALKFLHSKGIVYRDLKPENC 312
+++++L Y GELF L+ Q ++E + +L+ AL + HSKG+++RD+KPEN
Sbjct: 116 RVFVILDYASRGELFNVLQSQPGHKVNEVIAGRFVRQLANALHYCHSKGVIHRDIKPENL 175
Query: 313 LLNERGHLVLTDFGLSKKSVFDDAATPEEGENVNQLYSIIGTPEYCAPEILAGEPYTQNC 372
LL+ + +L L DFG S + + ++ +++ GT +Y APE+++ +P+ N
Sbjct: 176 LLDSKLNLKLADFGWSVVA------------DHSKRHTLCGTMDYLAPEMVSNQPHDFNV 223
Query: 373 DWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQEKTGARIPSYLSDGFKDYLGALLRKDP 432
D +++G L+++ML+G PF ++ +IK+ K IPS ++DG + A+++K+P
Sbjct: 224 DIWAIGILLFEMLVGYAPFANQTGDKLIARIKECK--IYIPSVVTDGAASLINAIIKKEP 281
Query: 433 TKR 435
+R
Sbjct: 282 QER 284
>Hs22066167 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 147
Score = 136 bits (342), Expect = 1e-31
Identities = 72/151 (47%), Positives = 91/151 (59%), Gaps = 10/151 (6%)
Query: 223 KRIERTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGT 282
K T AE IL ++ HP IV L Y+F KLYL+L+Y+ GGELF L+ +G E T
Sbjct: 7 KDTAHTKAEWNILEEVRHPFIVDLTYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDT 66
Query: 283 VAFYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEG 342
FY AE+S AL LH KGI+YRDLKPEN +LN +GH+ LTDFGL K+S+ D T
Sbjct: 67 ACFYLAEISMALGHLHQKGIIYRDLKPENIILNHQGHMKLTDFGLRKESIHDGTVT---- 122
Query: 343 ENVNQLYSIIGTPEYCAPEILAGEPYTQNCD 373
++ GT EY APEIL + + D
Sbjct: 123 ------HTFCGTIEYMAPEILMRSGHNRAVD 147
>Hs4506529 [T] KOG0986 G protein-coupled receptor kinase
Length = 563
Score = 135 bits (341), Expect = 1e-31
Identities = 86/274 (31%), Positives = 134/274 (48%), Gaps = 29/274 (10%)
Query: 168 DDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIER 227
D F+ R LG+G +G YA K+L K + K +
Sbjct: 188 DWFLDFRVLGKGGFGEVSACQMKATGKLYACKKLNKKRL-------------KKRKGYQG 234
Query: 228 TFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHL----KEQGTLDEGTV 283
E+ IL ++ IV L Y+F L LV+ + GG++ YH+ +E E
Sbjct: 235 AMVEKKILMKVHSRFIVSLAYAFETKADLCLVMTIMNGGDIRYHIYNVNEENPGFPEPRA 294
Query: 284 AFYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGE 343
FY A++ C L+ LH + IVYRDLKPEN LL+ G++ ++D GL+ + + +G+
Sbjct: 295 LFYTAQIICGLEHLHQRRIVYRDLKPENVLLDNDGNVRISDLGLAVELL--------DGQ 346
Query: 344 NVNQLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKI 403
+ + Y+ GTP + APE+L GE Y + D+++LG +Y+M+ + PF K+ ++
Sbjct: 347 SKTKGYA--GTPGFMAPELLQGEEYDFSVDYFALGVTLYEMIAARGPFRARGEKVENKEL 404
Query: 404 KQE--KTGARIPSYLSDGFKDYLGALLRKDPTKR 435
K + P S KD+ ALL KDP KR
Sbjct: 405 KHRIISEPVKYPDKFSQASKDFCEALLEKDPEKR 438
>CE03492 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 379
Score = 135 bits (341), Expect = 1e-31
Identities = 88/241 (36%), Positives = 119/241 (48%), Gaps = 30/241 (12%)
Query: 156 SSFSKTGAPRVLDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEK 215
SS S AP L F IR +G GA+G +A+K + K IEK
Sbjct: 15 SSVSGKSAP-CLQHFSVIRSIGRGAFGKVCIVQERKTKKYFALKYMNKRRC------IEK 67
Query: 216 DANTTVEKRIERTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQ 275
V + E T+LS++ HP IV L+Y+F D +Y+V + GG+L YHL +Q
Sbjct: 68 GVAANVIR-------ELTLLSKMSHPFIVNLWYTFQDGDYMYMVSDLLLGGDLRYHLSQQ 120
Query: 276 GTLDEGTVAFYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDD 335
G E Y E+ A+++LH IV+RD+KPEN LL+E+GH LTD L+ + D
Sbjct: 121 GKFAEDRAKLYLCEICLAVEYLHEMKIVHRDIKPENILLDEQGHAHLTDLNLATQLEDDQ 180
Query: 336 AATPEEGENVNQLYSIIGTPEYCAPEILA-----GEPYTQNCDWYSLGCLVYDMLIGKPP 390
AT S GT Y APEI A + Y DW++LG Y+ML G+ P
Sbjct: 181 LAT-----------SYSGTRPYMAPEIYATYLEIEDGYDSRVDWWALGVCFYEMLRGRTP 229
Query: 391 F 391
F
Sbjct: 230 F 230
>CE01554 [T] KOG0986 G protein-coupled receptor kinase
Length = 642
Score = 135 bits (341), Expect = 1e-31
Identities = 87/265 (32%), Positives = 136/265 (50%), Gaps = 32/265 (12%)
Query: 174 RCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIERTFA--E 231
R LG+G +G YA+K+L+K V+KR T + E
Sbjct: 207 RVLGKGGFGEVCACQVRASGKMYALKKLEKKR---------------VKKRHAETLSLNE 251
Query: 232 RTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKE--QGTLDEGTVAFYAAE 289
+ IL ++ P +V L Y++ L LVL + GG+L +HL G DE V FYAAE
Sbjct: 252 KQILQRINSPFVVSLAYAYETKDALCLVLTLMNGGDLKFHLYNLMPGGFDEKRVQFYAAE 311
Query: 290 LSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVNQLY 349
++ L+ LHS+ I+YRDLKPEN LL++ GH+ ++D GL+ + ++ P +G
Sbjct: 312 ITLGLQHLHSERILYRDLKPENILLDDFGHVRISDLGLAVEIKDNE---PIKGR------ 362
Query: 350 SIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQ--EK 407
+GT Y APEI+ E Y+ DW+ +GCL+Y+M+ GK PF K+ ++++ +
Sbjct: 363 --VGTVGYMAPEIVKNERYSYGVDWWGVGCLIYEMIEGKAPFRQRKEKVKREEVERRVRE 420
Query: 408 TGARIPSYLSDGFKDYLGALLRKDP 432
+ S+ + LL K+P
Sbjct: 421 DQEKYSEKFSEAARTLCRGLLHKEP 445
>Hs4502553 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 370
Score = 135 bits (339), Expect = 2e-31
Identities = 86/244 (35%), Positives = 136/244 (55%), Gaps = 19/244 (7%)
Query: 202 KKAEILISEDSIEKDANTTVEKRIERTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQ 261
K+ + L++ I K+A E +E A +L +++HPNIV L + LYL++Q
Sbjct: 40 KRTQKLVAIKCIAKEALEGKEGSMENEIA---VLHKIKHPNIVALDDIYESGGHLYLIMQ 96
Query: 262 YIPGGELFYHLKEQGTLDEGTVAFYAAELSCALKFLHSKGIVYRDLKPENCL---LNERG 318
+ GGELF + E+G E + ++ A+K+LH GIV+RDLKPEN L L+E
Sbjct: 97 LVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLGIVHRDLKPENLLYYSLDEDS 156
Query: 319 HLVLTDFGLSKKSVFDDAATPEEGENVNQLYSIIGTPEYCAPEILAGEPYTQNCDWYSLG 378
++++DFGLSK E+ +V L + GTP Y APE+LA +PY++ D +S+G
Sbjct: 157 KIMISDFGLSKM---------EDPGSV--LSTACGTPGYVAPEVLAQKPYSKAVDCWSIG 205
Query: 379 CLVYDMLIGKPPFTGVNHKIILNKIKQEKTGARIPSY--LSDGFKDYLGALLRKDPTKRW 436
+ Y +L G PPF N + +I + + P + +SD KD++ L+ KDP KR+
Sbjct: 206 VIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISDSAKDFIRHLMEKDPEKRF 265
Query: 437 DVDK 440
++
Sbjct: 266 TCEQ 269
>CE03979 [T] KOG0614 cGMP-dependent protein kinase
Length = 581
Score = 134 bits (338), Expect = 3e-31
Identities = 92/329 (27%), Positives = 161/329 (47%), Gaps = 33/329 (10%)
Query: 107 RRSSLYNKFVVNPAQHTIRLSLNAQGDSDKETRDVLSVSSVEETRQLRASSFSKTGAPRV 166
R+ FV+ H I++ + ++ L + +++ + RASS + A
Sbjct: 219 RKGRFERFFVLEGPAHLIKMHV-------EQLCKALDTTDLDDEIRPRASSTIEE-ADVE 270
Query: 167 LDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIE 226
L+D + LG G +G YA+K + KA I+ + K+
Sbjct: 271 LEDLQRVSTLGMGGFGRVELVRSASSRT-YALKIMNKAHIVET-------------KQES 316
Query: 227 RTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFY 286
+ER IL Q ++ IV+++ ++ D+ K+Y++++ GGE++ L+++G D FY
Sbjct: 317 HVVSERRILMQCDNDYIVRMYKTYRDSEKIYMLMEPCLGGEIWTILRKKGRFDNDLTRFY 376
Query: 287 AAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVN 346
A AL++LH K IVYRDLKPEN LL+ G L DFG +KK +N
Sbjct: 377 CAGAMEALEYLHRKNIVYRDLKPENMLLDRNGWPKLVDFGFAKKL-----------KNGG 425
Query: 347 QLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQE 406
+ ++ GT EY APEI+ + + + D ++LG + ++L G PPF+ + + N I +
Sbjct: 426 RTWTFCGTAEYVAPEIVLNKGHDLSVDIWALGIFMCELLTGSPPFSSTDPMVTYNAILKG 485
Query: 407 KTGARIPSYLSDGFKDYLGALLRKDPTKR 435
P +++ D + +L + +PT+R
Sbjct: 486 LEKWAWPRFVTKEAIDMMLSLCKYEPTER 514
>7302050 [T] KOG0986 G protein-coupled receptor kinase
Length = 714
Score = 134 bits (337), Expect = 4e-31
Identities = 88/265 (33%), Positives = 127/265 (47%), Gaps = 35/265 (13%)
Query: 164 PRVLDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEK 223
P F R LG+G +G YA K+L+K I K
Sbjct: 303 PITYKTFRMYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRI-------------KKRK 349
Query: 224 RIERTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGT---LDE 280
E+ IL ++ P +V L Y++ L LVL + GG+L +H+ G +
Sbjct: 350 GESMVLIEKQILQKINSPFVVNLAYAYETKDALCLVLTIMNGGDLKFHIYNMGGEPGFEL 409
Query: 281 GTVAFYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPE 340
FYAAE++C L+ LH +GIVYRD KPEN LL++ GH+ ++D GL A
Sbjct: 410 ERARFYAAEVACGLQHLHKQGIVYRDCKPENILLDDHGHVRISDLGL--------AVEIP 461
Query: 341 EGENVNQLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIIL 400
EGE V +GT Y APE++ E Y + DW+S GCL+Y+M+ G+ PF ++
Sbjct: 462 EGEMVR---GRVGTVGYMAPEVIDNEKYAFSPDWFSFGCLLYEMIEGQAPF-----RMRK 513
Query: 401 NKIKQEKTGARI---PSYLSDGFKD 422
K+K+E+ R+ P S F D
Sbjct: 514 EKVKREEVDRRVKEDPEKYSSKFND 538
>CE28739 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 632
Score = 133 bits (335), Expect = 6e-31
Identities = 92/330 (27%), Positives = 158/330 (47%), Gaps = 49/330 (14%)
Query: 137 ETRDVLSVSSVEETRQLRASSFSKTGAPRVLDDFVPIRCLGEGAYGXXXXXXXXXXXXXY 196
E+ + LS + E+ L A S + R +DF+ ++ +GEGAY +
Sbjct: 39 ESENSLSPVTAED---LIAKSIKEGCPKRTSNDFMFLQSMGEGAYSQVFRCREVATDAMF 95
Query: 197 AMKQLKKAEILISEDSIEKDANTTVEKRIERTFAERTILSQLE-----HPNIVKLFYSFH 251
A+K L+K+ + ++++ E+ IL+ L HP + +L+ FH
Sbjct: 96 AVKVLQKSYL-------------NRHQKMDAIIREKNILTYLSQECGGHPFVTQLYTHFH 142
Query: 252 DNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAAELSCALKFLHSKGIVYRDLKPEN 311
D ++Y V+ + G+L L G+ D T F+A+E+ L+FLH IV+RD+KP+N
Sbjct: 143 DQARIYFVIGLVENGDLGESLCHFGSFDMLTSKFFASEILTGLQFLHDNKIVHRDMKPDN 202
Query: 312 CLLNERGHLVLTDFG---------LSKKSVFD---------DAATP--------EEGENV 345
L+ + GH+++TDFG LS++ D D+ +P EE EN
Sbjct: 203 VLIQKDGHILITDFGSAQAFGGLQLSQEGFTDANQASSRSSDSGSPPPTRFYSDEEEENT 262
Query: 346 NQLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQ 405
+ + +GT Y +PE+LA D + LGC+++ L G+PPF VN +L +I
Sbjct: 263 ARRTTFVGTALYVSPEMLADGDVGPQTDIWGLGCILFQCLAGQPPFRAVNQYHLLKRI-- 320
Query: 406 EKTGARIPSYLSDGFKDYLGALLRKDPTKR 435
++ P + + + +L +DP+ R
Sbjct: 321 QELDFSFPEGFPEEASEIIAKILVRDPSTR 350
>Hs9966875 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 357
Score = 132 bits (333), Expect = 1e-30
Identities = 87/270 (32%), Positives = 137/270 (50%), Gaps = 31/270 (11%)
Query: 176 LGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIERTFAERTIL 235
LG GA+ +A+K + K + E SIE E +L
Sbjct: 29 LGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKESSIEN---------------EIAVL 73
Query: 236 SQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAAELSCALK 295
+++H NIV L + + LYLV+Q + GGELF + E+G E + ++ A+
Sbjct: 74 RKIKHENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVY 133
Query: 296 FLHSKGIVYRDLKPENCLL---NERGHLVLTDFGLSKKSVFDDAATPEEGENVNQLYSII 352
+LH GIV+RDLKPEN L +E ++++DFGLSK EG+ + + +
Sbjct: 134 YLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSKM----------EGKG-DVMSTAC 182
Query: 353 GTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQEKTGARI 412
GTP Y APE+LA +PY++ D +S+G + Y +L G PPF N + +I + +
Sbjct: 183 GTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDS 242
Query: 413 PSY--LSDGFKDYLGALLRKDPTKRWDVDK 440
P + +SD KD++ L+ KDP KR+ ++
Sbjct: 243 PYWDDISDSAKDFIRNLMEKDPNKRYTCEQ 272
>Hs18552621 [R] KOG0597 Serine-threonine protein kinase FUSED
Length = 1315
Score = 132 bits (333), Expect = 1e-30
Identities = 87/269 (32%), Positives = 133/269 (49%), Gaps = 27/269 (10%)
Query: 167 LDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIE 226
++ + + +GEG++G A+K + K EK +
Sbjct: 1 MEKYHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLG--------------RSEKELR 46
Query: 227 RTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFY 286
E I+ L HPNIV + SF + ++ +V Y G ELF L++ G L E V
Sbjct: 47 NLQREIEIMRGLRHPNIVHMLDSFETDKEVVVVTDYAEG-ELFQILEDDGKLPEDQVQAI 105
Query: 287 AAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVN 346
AA+L AL +LHS I++RD+KP+N LL + G + L DFG ++ N
Sbjct: 106 AAQLVSALYYLHSHRILHRDMKPQNILLAKGGGIKLCDFGFARAM----------STNTM 155
Query: 347 QLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQE 406
L SI GTP Y +PE++ PY D +S+GC++Y++ +G PPF + +++ I
Sbjct: 156 VLTSIKGTPLYMSPELVEERPYDHTADLWSVGCILYELAVGTPPFYATSIFQLVSLIL-- 213
Query: 407 KTGARIPSYLSDGFKDYLGALLRKDPTKR 435
K R PS +S FK++L LL KDP +R
Sbjct: 214 KDPVRWPSTISPCFKNFLQGLLTKDPRQR 242
>CE19898 [T] KOG0614 cGMP-dependent protein kinase
Length = 737
Score = 132 bits (332), Expect = 1e-30
Identities = 79/235 (33%), Positives = 122/235 (51%), Gaps = 25/235 (10%)
Query: 158 FSKTGAPRVLDDFVPIRCLGEGAYGXXXXX-XXXXXXXXYAMKQLKKAEILISEDSIEKD 216
F + A L + + LG G +G +A+K LKK I+ +
Sbjct: 414 FREEFAQVTLKNVKRLATLGVGGFGRVELVCVNGDKAKTFALKALKKKHIVDTRQQ---- 469
Query: 217 ANTTVEKRIERTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQG 276
E FAER I+ + IVKL+ +F D +Y++L+ GGEL+ L+++G
Sbjct: 470 ---------EHIFAERNIMMETSTDWIVKLYKTFRDQKFVYMLLEVCLGGELWTTLRDRG 520
Query: 277 TLDEGTVAFYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDA 336
D+ T FY A + L++LH K IVYRDLKPENCLL G+L L DFG +KK
Sbjct: 521 HFDDYTARFYVACVLEGLEYLHRKNIVYRDLKPENCLLANTGYLKLVDFGFAKKLA---- 576
Query: 337 ATPEEGENVNQLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPF 391
+ + ++ GTPEY +PEI+ + + Q D+++LG + ++++G+PPF
Sbjct: 577 -------SGRKTWTFCGTPEYVSPEIILNKGHDQAADYWALGIYICELMLGRPPF 624
>CE19897 [T] KOG0614 cGMP-dependent protein kinase
Length = 780
Score = 132 bits (332), Expect = 1e-30
Identities = 79/235 (33%), Positives = 122/235 (51%), Gaps = 25/235 (10%)
Query: 158 FSKTGAPRVLDDFVPIRCLGEGAYGXXXXX-XXXXXXXXYAMKQLKKAEILISEDSIEKD 216
F + A L + + LG G +G +A+K LKK I+ +
Sbjct: 457 FREEFAQVTLKNVKRLATLGVGGFGRVELVCVNGDKAKTFALKALKKKHIVDTRQQ---- 512
Query: 217 ANTTVEKRIERTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQG 276
E FAER I+ + IVKL+ +F D +Y++L+ GGEL+ L+++G
Sbjct: 513 ---------EHIFAERNIMMETSTDWIVKLYKTFRDQKFVYMLLEVCLGGELWTTLRDRG 563
Query: 277 TLDEGTVAFYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDA 336
D+ T FY A + L++LH K IVYRDLKPENCLL G+L L DFG +KK
Sbjct: 564 HFDDYTARFYVACVLEGLEYLHRKNIVYRDLKPENCLLANTGYLKLVDFGFAKKLA---- 619
Query: 337 ATPEEGENVNQLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPF 391
+ + ++ GTPEY +PEI+ + + Q D+++LG + ++++G+PPF
Sbjct: 620 -------SGRKTWTFCGTPEYVSPEIILNKGHDQAADYWALGIYICELMLGRPPF 667
>CE08098 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1173
Score = 131 bits (329), Expect = 3e-30
Identities = 84/274 (30%), Positives = 130/274 (46%), Gaps = 33/274 (12%)
Query: 169 DFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIERT 228
DF ++ +G GA+G YAMK L K +++ KR +
Sbjct: 67 DFRQLKVIGRGAFGEVHLVRHTRTNTVYAMKMLNKDDMI---------------KRADSA 111
Query: 229 F--AERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFY 286
F ER I++ IV+L Y+F D LY+V++Y+PGG+L +L + E FY
Sbjct: 112 FFWEERDIMAHANSEWIVRLQYAFQDPRHLYMVMEYMPGGDLV-NLMTSYEVSEKWTRFY 170
Query: 287 AAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVN 346
AE+ AL LHS G ++RD+KP+N L++ GH+ L DFG K V
Sbjct: 171 TAEIVEALAALHSMGYIHRDVKPDNMLISISGHIKLADFGTCVKM---------NANGVV 221
Query: 347 QLYSIIGTPEYCAPEILAGE----PYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNK 402
+ + +GTP+Y +PE+L + + + DW+S+G +Y+ML+G+ PF
Sbjct: 222 RCSTAVGTPDYISPEVLRNQGQDAEFGKEVDWWSVGVFIYEMLVGETPFYAEALVSTYTN 281
Query: 403 IKQEKTGARIPS--YLSDGFKDYLGALLRKDPTK 434
I KT + P +S KD + L P +
Sbjct: 282 IMNHKTSLKFPDEPLISTQAKDIIKKFLSAAPDR 315
>YGR092w [R] KOG0605 NDR and related serine/threonine kinases
Length = 572
Score = 130 bits (327), Expect = 5e-30
Identities = 89/303 (29%), Positives = 142/303 (46%), Gaps = 50/303 (16%)
Query: 169 DFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIERT 228
DF I +G+G YG A+K L K + ++ +
Sbjct: 176 DFEMITQVGQGGYGQVYLARKKDTKEVCALKILNKKLLFKLNET-------------KHV 222
Query: 229 FAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAA 288
ER IL+ +VKL Y+F D LYL ++++PGG+ L L G FY +
Sbjct: 223 LTERDILTTTRSEWLVKLLYAFQDLQSLYLAMEFVPGGDFRTLLINTRCLKSGHARFYIS 282
Query: 289 ELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDD------------- 335
E+ CA+ LH G +RDLKPEN L++ +GH+ LTDFGL+ ++ ++
Sbjct: 283 EMFCAVNALHDLGYTHRDLKPENFLIDAKGHIKLTDFGLAAGTISNERIESMKIRLEKIK 342
Query: 336 -----AATPEEGENVNQLY------------SIIGTPEYCAPEILAGEPYTQNCDWYSLG 378
A T + E+ ++Y S++G+P+Y A E+L G+ Y D++SLG
Sbjct: 343 DLEFPAFTEKSIEDRRKMYNQLREKEINYANSMVGSPDYMALEVLEGKKYDFTVDYWSLG 402
Query: 379 CLVYDMLIGKPPFTGVNHKIILNKIKQEKTGARIPSYLSDG---FKDYLGALLRK---DP 432
C++++ L+G PF+G + + +++ K R P SDG F D L+ + DP
Sbjct: 403 CMLFESLVGYTPFSGSSTNETYDNLRRWKQTLRRPRQ-SDGRAAFSDRTWDLITRLIADP 461
Query: 433 TKR 435
R
Sbjct: 462 INR 464
>Hs4885055 [T] KOG0986 G protein-coupled receptor kinase
Length = 688
Score = 130 bits (327), Expect = 5e-30
Identities = 90/280 (32%), Positives = 135/280 (48%), Gaps = 42/280 (15%)
Query: 167 LDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIE 226
+++F R +G G +G YAMK L K I +++ + +RI
Sbjct: 188 MNEFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRI-----KMKQGETLALNERIM 242
Query: 227 RTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFY 286
+ ++S + P IV + Y+FH KL +L + GG+L YHL + G E + FY
Sbjct: 243 LS-----LVSTGDCPFIVCMTYAFHTPDKLCFILDLMNGGDLHYHLSQHGVFSEKEMRFY 297
Query: 287 AAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGL----SKKSVFDDAATPEEG 342
A E+ L+ +H++ +VYRDLKP N LL+E GH ++D GL SKK
Sbjct: 298 ATEIILGLEHVHNRFVVYRDLKPANILLDEHGHARISDLGLACDFSKK------------ 345
Query: 343 ENVNQLYSIIGTPEYCAPEIL-AGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILN 401
+ ++ +GT Y APE+L G Y + DW+SLGC+++ +L G PF HK
Sbjct: 346 ----KPHASVGTHGYMAPEVLQKGTAYDSSADWFSLGCMLFKLLRGHSPFR--QHK---T 396
Query: 402 KIKQE------KTGARIPSYLSDGFKDYLGALLRKDPTKR 435
K K E +P S K L LL++D +KR
Sbjct: 397 KDKHEIDRMTLTVNVELPDTFSPELKSLLEGLLQRDVSKR 436
>Hs4501971 [T] KOG0986 G protein-coupled receptor kinase
Length = 689
Score = 130 bits (327), Expect = 5e-30
Identities = 90/280 (32%), Positives = 135/280 (48%), Gaps = 42/280 (15%)
Query: 167 LDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIE 226
++DF R +G G +G YAMK L K I +++ + +RI
Sbjct: 188 MNDFSVHRIIGRGGFGEVYGCRKRDTGKMYAMKCLDKKRI-----KMKQGETLALNERIM 242
Query: 227 RTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFY 286
+ ++S + P IV + Y+FH KL +L + GG+L YHL + G E + FY
Sbjct: 243 LS-----LVSTGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHGVFSEADMRFY 297
Query: 287 AAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGL----SKKSVFDDAATPEEG 342
AAE+ L+ +H++ +VYRDLKP N LL+E GH+ ++D GL SKK
Sbjct: 298 AAEIILGLEHMHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKK------------ 345
Query: 343 ENVNQLYSIIGTPEYCAPEIL-AGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILN 401
+ ++ +GT Y APE+L G Y + DW+SLGC+++ +L G PF HK
Sbjct: 346 ----KPHASVGTHGYMAPEVLQKGVAYDSSADWFSLGCMLFKLLRGHSPFR--QHK---T 396
Query: 402 KIKQE------KTGARIPSYLSDGFKDYLGALLRKDPTKR 435
K K E +P S L LL++D +R
Sbjct: 397 KDKHEIDRMTLTMAVELPDSFSPELHSLLEGLLQRDVNRR 436
>7297776 [D] KOG0580 Serine/threonine protein kinase
Length = 329
Score = 130 bits (327), Expect = 5e-30
Identities = 90/277 (32%), Positives = 136/277 (48%), Gaps = 33/277 (11%)
Query: 176 LGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIERTFAERTIL 235
LG G +G AMK + K E+ V++++ R E I
Sbjct: 59 LGRGKFGRVYLARERHSHYLVAMKVMFKEEL----------RKGCVQRQVLR---EIEIQ 105
Query: 236 SQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLK--EQGTLDEGTVAFYAAELSCA 293
S+L+HP+I++L FHD ++YL L+ GELF HL+ DE A Y +++ A
Sbjct: 106 SRLKHPHILRLLTWFHDESRIYLALEIASEGELFKHLRGAPNHRFDEPRSAKYTYQVANA 165
Query: 294 LKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVNQLYSIIG 353
L + H +++RDLKPEN LL L L DFG S A TP N+ ++ G
Sbjct: 166 LNYCHLNNVIHRDLKPENILLTSTDDLKLADFGWS-------AHTPN-----NKRRTLCG 213
Query: 354 TPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQEKTGARIP 413
T +Y PE++ G Y + D + LG L Y+ ++G PPF + + +KI++ + P
Sbjct: 214 TLDYLPPEMVDGNSYDDSVDQWCLGILCYEFVVGCPPFESNSTESTYSKIRRMEIS--YP 271
Query: 414 SYLSDGFKDYLGALLRKDPTKRWD----VDKYWAQDG 446
S+LS G K+ +G LLRK+ R + YW + G
Sbjct: 272 SHLSKGCKELIGGLLRKESKGRITLVDVMTHYWVKAG 308
>Hs21166359 [T] KOG0986 G protein-coupled receptor kinase
Length = 553
Score = 130 bits (326), Expect = 7e-30
Identities = 90/273 (32%), Positives = 131/273 (47%), Gaps = 32/273 (11%)
Query: 170 FVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIERTF 229
F R LG+G +G YA K+L K + + EK A
Sbjct: 191 FTEFRVLGKGGFGEVCAVQVKNTGKMYACKKLDKKRL--KKKGGEKMA-----------L 237
Query: 230 AERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGT--LDEGTVAFYA 287
E+ IL ++ P IV L Y+F L LV+ + GG+L +H+ GT LD V FY+
Sbjct: 238 LEKEILEKVSSPFIVSLAYAFESKTHLCLVMSLMNGGDLKFHIYNVGTRGLDMSRVIFYS 297
Query: 288 AELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVNQ 347
A+++C + LH GIVYRD+KPEN LL++ G+ L+D GL A + G+ + Q
Sbjct: 298 AQIACGMLHLHELGIVYRDMKPENVLLDDLGNCRLSDLGL--------AVEMKGGKPITQ 349
Query: 348 LYSIIGTPEYCAPEILAGE-PYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQE 406
GT Y APEIL + Y+ DW+++GC +Y+M+ G+ PF K+ +KQ
Sbjct: 350 R---AGTNGYMAPEILMEKVSYSYPVDWFAMGCSIYEMVAGRTPFKDYKEKVSKEDLKQR 406
Query: 407 KTGARIPSYLSDGF----KDYLGALLRKDPTKR 435
+ + D F KD L K P +R
Sbjct: 407 TLQDEV-KFQHDNFTEEAKDICRLFLAKKPEQR 438
>7299322 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 434
Score = 130 bits (326), Expect = 7e-30
Identities = 91/288 (31%), Positives = 141/288 (48%), Gaps = 29/288 (10%)
Query: 163 APRVLDDFVP---IRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANT 219
AP +++ + I+ LG+G YG A+K +KK +I D +
Sbjct: 72 APELIESILKFDIIKKLGQGTYGKVQLGINKETGQEVAIKTIKKCKIEAEADLV------ 125
Query: 220 TVEKRIERTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLD 279
RI R E I+S + HPNI+ ++ F + K+ LV+++ GGEL+ +L E+ L
Sbjct: 126 ----RIRR---EVQIMSSVHHPNIIHIYEVFENREKMVLVMEFAAGGELYDYLSERKVLT 178
Query: 280 EGTVAFYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATP 339
E +++ A+ + H I +RDLK EN LL+E+G+ + DFGLS +VFDD
Sbjct: 179 EEEARRIFRQVATAVYYCHKHKICHRDLKLENILLDEKGNAKIADFGLS--NVFDDQ--- 233
Query: 340 EEGENVNQLYSIIGTPEYCAPEILAGEPYT-QNCDWYSLGCLVYDMLIGKPPFTGVNHKI 398
L + G+P Y +PEI+ G PY D +SLG L+Y ++ G PF G N K
Sbjct: 234 ------RLLGTFCGSPLYASPEIVEGTPYQGPEVDCWSLGVLLYTLVYGSMPFDGSNFKR 287
Query: 399 ILNKIKQ-EKTGARIPSYLSDGFKDYLGALLRKDPTKRWDVDKYWAQD 445
++ +I Q + R PS S +D L RK + +W +
Sbjct: 288 LVKQISQGDYYEPRKPSRASTLIRDMLTVCPRKRASIEQICSHWWVNE 335
>7293249 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1390
Score = 129 bits (325), Expect = 9e-30
Identities = 106/365 (29%), Positives = 166/365 (45%), Gaps = 53/365 (14%)
Query: 167 LDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIE 226
++DF I+ +G GA+G YAMK+L K E++ DS
Sbjct: 84 VEDFHFIKLIGAGAFGEVQLVRHKSSSQVYAMKRLSKFEMMKRPDSAF------------ 131
Query: 227 RTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFY 286
+ ER I++ IV+L ++F D LY+V+ ++PGG++ L + E FY
Sbjct: 132 -FWEERHIMAHANSEWIVQLHFAFQDAKYLYMVMDFMPGGDIV-SLMGDYDIPEKWAIFY 189
Query: 287 AAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVN 346
E+ AL +H+ G V+RD+KP+N LL+ GHL L DFG + G+ V+
Sbjct: 190 TMEVVLALDTIHNMGFVHRDVKPDNMLLDSYGHLKLADFGTCMR-------MGANGQVVS 242
Query: 347 QLYSIIGTPEYCAPEILAGE----PYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNK 402
+ +GTP+Y +PE+L + Y + CDW+S+G +Y+ML G+ PF + K
Sbjct: 243 S--NAVGTPDYISPEVLQSQGVDNEYGRECDWWSVGIFLYEMLFGETPFYADSLVGTYGK 300
Query: 403 IKQEKTGARIPS--YLSDGFKDYLGALLRKDPTKRWDVDKYWAQDGPXXXXXXXXXXXXX 460
I K P +S+ K + A L D T+R + +Y +D
Sbjct: 301 IMDHKNSLSFPPEVEISEQAKALIRAFL-TDRTQR--LGRYGIED--------------- 342
Query: 461 NYIGHFIFRKIIWKQLLSGDLQKISVGPILPIITDWELAENF-DTEFTEKRLDTSIYDNG 519
H FR W S D + SV P++P ++ + NF D E EK + G
Sbjct: 343 -IKAHPFFRNDTW----SFDNIRESVPPVVPELSSDDDTRNFEDIERDEKPEEVFPVPKG 397
Query: 520 IEINN 524
+ N+
Sbjct: 398 FDGNH 402
>At4g24400 [T] KOG0583 Serine/threonine protein kinase
Length = 445
Score = 129 bits (324), Expect = 1e-29
Identities = 83/263 (31%), Positives = 132/263 (49%), Gaps = 26/263 (9%)
Query: 174 RCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIERTFAERT 233
R +GEG + AMK + ++ I+ K +++ E +
Sbjct: 13 RTIGEGTFAKVKFAQNTETGESVAMKIVDRSTII-------------KRKMVDQIKREIS 59
Query: 234 ILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAAELSCA 293
I+ + HP +V+L+ K+Y++L+YI GGELF + G L E Y +L
Sbjct: 60 IMKLVRHPCVVRLYEVLASRTKIYIILEYITGGELFDKIVRNGRLSESEARKYFHQLIDG 119
Query: 294 LKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVNQLYSIIG 353
+ + HSKG+ +RDLKPEN LL+ +G+L ++DFGLS A PE+G V L + G
Sbjct: 120 VDYCHSKGVYHRDLKPENLLLDSQGNLKISDFGLS--------ALPEQG--VTILKTTCG 169
Query: 354 TPEYCAPEILAGEPYT-QNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQEKTGARI 412
TP Y APE+L+ + Y D +S G ++Y ++ G PF ++ + +KI +K
Sbjct: 170 TPNYVAPEVLSHKGYNGAVADIWSCGVILYVLMAGYLPFDEMDLPTLYSKI--DKAEFSC 227
Query: 413 PSYLSDGFKDYLGALLRKDPTKR 435
PSY + G K + +L +P R
Sbjct: 228 PSYFALGAKSLINRILDPNPETR 250
>At3g14370 [R] KOG0610 Putative serine/threonine protein kinase
Length = 480
Score = 129 bits (323), Expect = 2e-29
Identities = 110/368 (29%), Positives = 165/368 (43%), Gaps = 60/368 (16%)
Query: 115 FVVNPAQHTIRLSLNAQ-GDSDKETRDVLSVSSVEETRQ------LRASSFSKTGAPRVL 167
F + A+ ++ LS N + S T S SSV R ++++ + L
Sbjct: 26 FASSSARTSLTLSFNDRLSTSSAVTTSSTSSSSVNHRRHDPHWSAIKSAKLLSSDGNIHL 85
Query: 168 DDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIER 227
IR LG G G +A+K I+++ TT EK++ +
Sbjct: 86 RHLKLIRHLGTGNLGRVFLCNLRDSSARFALKV------------IDRNCLTT-EKKLSQ 132
Query: 228 TFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQ--GTLDEGTVAF 285
E ILS L+HP + L+ ++H L++ Y P G+L L++Q L V F
Sbjct: 133 VETEAEILSLLDHPFLPTLYARIDESHYTCLLIDYAPNGDLHSLLRKQPGNRLPIQPVRF 192
Query: 286 YAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKS-------------- 331
+AAE+ AL++LH+ GIVYRDLKPEN LL E GH++L+DF L KS
Sbjct: 193 FAAEVLVALEYLHAMGIVYRDLKPENVLLREDGHVMLSDFDLCFKSDVVPTFKSRRYRRS 252
Query: 332 ------------VFDDAATP--EEGENVNQL---------YSIIGTPEYCAPEILAGEPY 368
F AA E E V++ S +GT EY APE+++G +
Sbjct: 253 SSSPSLRRRRSGCFSVAAEKKYEREEIVSEFAAEPVTAFSRSCVGTHEYLAPELVSGNGH 312
Query: 369 TQNCDWYSLGCLVYDMLIGKPPFTGVN-HKIILNKIKQEKTGARIPSYLSDGFKDYLGAL 427
DW++ G +Y++L G PF G + + + N + KT + D +D + L
Sbjct: 313 GSGVDWWAFGIFLYELLYGTTPFKGESKEQTLRNIVSTTKTASFHMDGDLDEARDLIEKL 372
Query: 428 LRKDPTKR 435
L KDP KR
Sbjct: 373 LVKDPRKR 380
>CE28740 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 636
Score = 128 bits (322), Expect = 2e-29
Identities = 92/332 (27%), Positives = 158/332 (46%), Gaps = 51/332 (15%)
Query: 137 ETRDVLSVSSVEETRQLRASSFSKTGAPRVLDDFVPIRCLGEGAYGXXXXXXXXXXXXXY 196
E+ + LS + E+ L A S + R +DF+ ++ +GEGAY +
Sbjct: 39 ESENSLSPVTAED---LIAKSIKEGCPKRTSNDFMFLQSMGEGAYSQVFRCREVATDAMF 95
Query: 197 AMKQLKKAEILISEDSIEKDANTTVEKRIERTFAERTILSQLE-----HPNIVKLFYSFH 251
A+K L+K+ + ++++ E+ IL+ L HP + +L+ FH
Sbjct: 96 AVKVLQKSYL-------------NRHQKMDAIIREKNILTYLSQECGGHPFVTQLYTHFH 142
Query: 252 DNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAAELSCALKFLHSKGIVYRDLKPEN 311
D ++Y V+ + G+L L G+ D T F+A+E+ L+FLH IV+RD+KP+N
Sbjct: 143 DQARIYFVIGLVENGDLGESLCHFGSFDMLTSKFFASEILTGLQFLHDNKIVHRDMKPDN 202
Query: 312 CLLNERGHLVLTDFG---------LSKKSVFD---------DAATP--------EE--GE 343
L+ + GH+++TDFG LS++ D D+ +P EE E
Sbjct: 203 VLIQKDGHILITDFGSAQAFGGLQLSQEGFTDANQASSRSSDSGSPPPTRFYSDEEVPEE 262
Query: 344 NVNQLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKI 403
N + + +GT Y +PE+LA D + LGC+++ L G+PPF VN +L +I
Sbjct: 263 NTARRTTFVGTALYVSPEMLADGDVGPQTDIWGLGCILFQCLAGQPPFRAVNQYHLLKRI 322
Query: 404 KQEKTGARIPSYLSDGFKDYLGALLRKDPTKR 435
++ P + + + +L +DP+ R
Sbjct: 323 --QELDFSFPEGFPEEASEIIAKILVRDPSTR 352
>7296166 [T] KOG0614 cGMP-dependent protein kinase
Length = 768
Score = 128 bits (322), Expect = 2e-29
Identities = 83/305 (27%), Positives = 147/305 (47%), Gaps = 26/305 (8%)
Query: 133 DSDKETRDVLSVSSVEETRQLRASSFSKTGAPRVLDDFVPIRCLGEGAYGXXXXXXXXXX 192
D E+R + + E R + L D + LG G +G
Sbjct: 420 DYGDESRKLAMKQAQESCRDEPKEQLQQEFPDLKLTDLEVVSTLGIGGFGRVELVKAHHQ 479
Query: 193 XXX--YAMKQLKKAEILISEDSIEKDANTTVEKRIERTFAERTILSQLEHPNIVKLFYSF 250
+A+K LKK I+ + K+ E F+ER I+ P I +L+ +F
Sbjct: 480 DRVDIFALKCLKKRHIVDT-------------KQEEHIFSERHIMLSSRSPFICRLYRTF 526
Query: 251 HDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAAELSCALKFLHSKGIVYRDLKPE 310
D +Y++L+ GGE++ L+++G+ ++ F + A ++LH++GI+YRDLKPE
Sbjct: 527 RDEKYVYMLLEACMGGEIWTMLRDRGSFEDNAAQFIIGCVLQAFEYLHARGIIYRDLKPE 586
Query: 311 NCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVNQLYSIIGTPEYCAPEILAGEPYTQ 370
N +L+ERG++ + DFG +K+ ++ ++ GTPEY APEI+ + + +
Sbjct: 587 NLMLDERGYVKIVDFGFAKQI-----------GTSSKTWTFCGTPEYVAPEIILNKGHDR 635
Query: 371 NCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQEKTGARIPSYLSDGFKDYLGALLRK 430
D+++LG L++++L G PPF+ + N I + P ++S + L R
Sbjct: 636 AVDYWALGILIHELLNGTPPFSAPDPMQTYNLILKGIDMIAFPKHISRWAVQLIKRLCRD 695
Query: 431 DPTKR 435
P++R
Sbjct: 696 VPSER 700
>CE27768 [R] KOG0586 Serine/threonine protein kinase
Length = 1096
Score = 127 bits (320), Expect = 3e-29
Identities = 75/216 (34%), Positives = 118/216 (53%), Gaps = 14/216 (6%)
Query: 225 IERTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVA 284
+++ F E I+ QL+HPNIVKL+ LYLVL+Y GGE+F +L G + E
Sbjct: 163 LQKLFREVKIMKQLDHPNIVKLYQVMETEQTLYLVLEYASGGEVFDYLVAHGRMKEKEAR 222
Query: 285 FYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGEN 344
++ A+++LHSK I++RDLK EN LL++ ++ + DFG S
Sbjct: 223 AKFRQIVSAVQYLHSKNIIHRDLKAENLLLDQDMNIKIADFGFSNTFSLG---------- 272
Query: 345 VNQLYSIIGTPEYCAPEILAGEPYT-QNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKI 403
N+L + G+P Y APE+ +G+ Y D +SLG ++Y ++ G PF G N K + ++
Sbjct: 273 -NKLDTFCGSPPYAAPELFSGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERV 331
Query: 404 KQEKTGARIPSYLSDGFKDYLGALLRKDPTKRWDVD 439
+ K RIP Y+S ++ L L +P +R +D
Sbjct: 332 LRGK--YRIPFYMSTDCENLLKKFLVINPQRRSSLD 365
>CE23838 [R] KOG0586 Serine/threonine protein kinase
Length = 1192
Score = 127 bits (320), Expect = 3e-29
Identities = 75/216 (34%), Positives = 118/216 (53%), Gaps = 14/216 (6%)
Query: 225 IERTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVA 284
+++ F E I+ QL+HPNIVKL+ LYLVL+Y GGE+F +L G + E
Sbjct: 211 LQKLFREVKIMKQLDHPNIVKLYQVMETEQTLYLVLEYASGGEVFDYLVAHGRMKEKEAR 270
Query: 285 FYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGEN 344
++ A+++LHSK I++RDLK EN LL++ ++ + DFG S
Sbjct: 271 AKFRQIVSAVQYLHSKNIIHRDLKAENLLLDQDMNIKIADFGFSNTFSLG---------- 320
Query: 345 VNQLYSIIGTPEYCAPEILAGEPYT-QNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKI 403
N+L + G+P Y APE+ +G+ Y D +SLG ++Y ++ G PF G N K + ++
Sbjct: 321 -NKLDTFCGSPPYAAPELFSGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERV 379
Query: 404 KQEKTGARIPSYLSDGFKDYLGALLRKDPTKRWDVD 439
+ K RIP Y+S ++ L L +P +R +D
Sbjct: 380 LRGK--YRIPFYMSTDCENLLKKFLVINPQRRSSLD 413
>7291742_1 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1539
Score = 127 bits (320), Expect = 3e-29
Identities = 124/430 (28%), Positives = 181/430 (41%), Gaps = 81/430 (18%)
Query: 135 DKETRDVLSVSS--VEETRQLRASSFSKTGAPRVLDDFVPIRCLGEGAYGXXXXXXXXXX 192
+K D L +S V R+LR S DDF ++ +G GA+G
Sbjct: 73 EKGVSDFLKLSKPFVHIVRKLRLSR----------DDFDILKIIGRGAFGEVCVVQMIST 122
Query: 193 XXXYAMKQLKKAEILISEDSIEKDANTTVEKRIERTFAERTILSQLEHPNIVKLFYSFHD 252
YAMK L K E+L K A T + ER +L + I L Y+F D
Sbjct: 123 EKVYAMKILNKWEML-------KRAETACFRE------ERDVLVFGDRQWITNLHYAFQD 169
Query: 253 NHKLYLVLQYIPGGELFYHL-KEQGTLDEGTVAFYAAELSCALKFLHSKGIVYRDLKPEN 311
N LYLV+ Y GG+L L K + L E FY E+ A+ +H V+RD+KP+N
Sbjct: 170 NINLYLVMDYYCGGDLLTLLSKFEDKLPEDMAKFYITEMILAINSIHQIRYVHRDIKPDN 229
Query: 312 CLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVNQLYSIIGTPEYCAPEILAGEP---- 367
LL++RGH+ L DFG + + + Q +GTP+Y +PEIL
Sbjct: 230 VLLDKRGHVRLADFG---------SCLRLDKDGTVQSNVAVGTPDYISPEILRAMEDGKG 280
Query: 368 -YTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQEKTGARIPSY------LSDGF 420
Y CDW+SLG +Y+ML G+ PF + KI + +PS +S+
Sbjct: 281 RYGTECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHQNCFNLPSQETLNYKVSETS 340
Query: 421 KDYLGALLRKDPTKRWDVDKYWAQDGPXXXXXXXXXXXXXNYIGHFIFRKIIWKQLLSGD 480
+D L L+ + Q+G +++ H F I WK + G
Sbjct: 341 QDLLCKLICIPENR-------LGQNG------------IQDFMDHPWFVGIDWKNIRQGP 381
Query: 481 LQKISVGPILPIITDWELAENFDTEFTEKRLDTSIYDNGIEINNPRATKESAFAGSTDYF 540
P +P ++ NFD + + RL SI + NP AF+G F
Sbjct: 382 ------APYVPEVSSPTDTSNFDVDDNDVRLTDSIPPSA----NP------AFSGFHLPF 425
Query: 541 KGFSYVASRS 550
GF++ + S
Sbjct: 426 IGFTFSLTSS 435
>Hs4885349 [T] KOG0986 G protein-coupled receptor kinase
Length = 590
Score = 127 bits (319), Expect = 4e-29
Identities = 88/278 (31%), Positives = 134/278 (47%), Gaps = 32/278 (11%)
Query: 164 PRVLDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEK 223
P + F R LG+G +G YA K+L+K I +K
Sbjct: 180 PVTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKRLEKKRI---------------KK 224
Query: 224 RIERTFA--ERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGT--LD 279
R + A E+ IL ++ +V L Y++ L LVL + GG+L +H+ G +
Sbjct: 225 RKGESMALNEKQILEKVNSQFVVNLAYAYETKDALCLVLTIMNGGDLKFHIYNMGNPGFE 284
Query: 280 EGTVAFYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATP 339
E FYAAE+ C L+ LH + VYRDLKPEN LL++ GH+ ++D GL+ K
Sbjct: 285 EERALFYAAEILCGLEDLHRENTVYRDLKPENILLDDYGHIRISDLGLAVKI-------- 336
Query: 340 EEGENVNQLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKII 399
EG+ + +GT Y APE+L + Y + D++ LGCL+Y+M+ G+ PF G K+
Sbjct: 337 PEGDLIR---GRVGTVGYMAPEVLNNQRYGLSPDYWGLGCLIYEMIEGQSPFRGRKEKVK 393
Query: 400 LNKIKQE--KTGARIPSYLSDGFKDYLGALLRKDPTKR 435
++ + +T S+ K LL KD +R
Sbjct: 394 REEVDRRVLETEEVYSHKFSEEAKSICKMLLTKDAKQR 431
>At4g32830 [D] KOG0580 Serine/threonine protein kinase
Length = 294
Score = 127 bits (318), Expect = 6e-29
Identities = 87/301 (28%), Positives = 143/301 (46%), Gaps = 28/301 (9%)
Query: 142 LSVSSVEETRQLRASSFSKTGAPR--VLDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMK 199
+++ + + ++ AS S A + L DF + LG G +G A+K
Sbjct: 1 MAIPTETQHQEKEASDASAAAAQKRWTLSDFDIGKPLGRGKFGHVYLAREKRSNHVVALK 60
Query: 200 QLKKAEILISEDSIEKDANTTVEKRIERTFAERTILSQLEHPNIVKLFYSFHDNHKLYLV 259
L K+++ S+ VE ++ R E I S L HPNI++L+ F+D ++YL+
Sbjct: 61 VLFKSQLQQSQ----------VEHQLRR---EVEIQSHLRHPNILRLYGYFYDQKRVYLI 107
Query: 260 LQYIPGGELFYHLKEQGTLDEGTVAFYAAELSCALKFLHSKGIVYRDLKPENCLLNERGH 319
L+Y GEL+ L++ E A Y A L+ AL + H K +++RD+KPEN L+ +G
Sbjct: 108 LEYAARGELYKDLQKCKYFSERRAATYVASLARALIYCHGKHVIHRDIKPENLLIGAQGE 167
Query: 320 LVLTDFGLSKKSVFDDAATPEEGENVNQLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGC 379
L + DFG S N+ ++ GT +Y PE++ + + D +SLG
Sbjct: 168 LKIADFGWSV-------------HTFNRRRTMCGTLDYLPPEMVESVEHDASVDIWSLGI 214
Query: 380 LVYDMLIGKPPFTGVNHKIILNKIKQEKTGARIPSYLSDGFKDYLGALLRKDPTKRWDVD 439
L Y+ L G PPF + H +I Q +S KD + +L K+ ++R +
Sbjct: 215 LCYEFLYGVPPFEAMEHSDTYRRIVQVDLKFPPKPIISASAKDLISQMLVKESSQRLPLH 274
Query: 440 K 440
K
Sbjct: 275 K 275
>7299437 [R] KOG0586 Serine/threonine protein kinase
Length = 604
Score = 127 bits (318), Expect = 6e-29
Identities = 77/224 (34%), Positives = 124/224 (54%), Gaps = 16/224 (7%)
Query: 213 IEKDANTTVEKRIERTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHL 272
I+K A T+ + ++ + E I+ +L HPNIV+L LYLV++Y+ GGELF +L
Sbjct: 94 IDKTALNTIAR--QKLYREVNIMKKLNHPNIVRLLQVIESERTLYLVMEYVSGGELFNYL 151
Query: 273 KEQGTLDEGTVAFYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSV 332
+ G + E +L A+++ HSK IV+RDLK EN LL+++ L + DFG S +
Sbjct: 152 VKNGRMRERDARVLFRQLVSAIEYCHSKSIVHRDLKAENLLLDQQMKLKIADFGFS--TT 209
Query: 333 FDDAATPEEGENVNQLYSIIGTPEYCAPEILAGEPYT-QNCDWYSLGCLVYDMLIGKPPF 391
F+ A L + G+P Y APE+ G+ Y+ D +SLG ++Y ++ G PF
Sbjct: 210 FEPKA---------PLETFCGSPPYAAPELFRGKKYSGPEVDSWSLGVVLYTLVSGSLPF 260
Query: 392 TGVNHKIILNKIKQEKTGARIPSYLSDGFKDYLGALLRKDPTKR 435
G N K + +++ + K R+P Y+S + + L +PT+R
Sbjct: 261 DGTNLKELRDRVLRGK--YRVPYYVSIECESLIRKFLVLNPTQR 302
>At4g14580 [T] KOG0583 Serine/threonine protein kinase
Length = 426
Score = 126 bits (317), Expect = 8e-29
Identities = 86/267 (32%), Positives = 128/267 (47%), Gaps = 23/267 (8%)
Query: 174 RCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIERTFAERT 233
R LG G++ A+K + K +K ++ +E RI R
Sbjct: 25 RRLGSGSFAKVHVARSISTGELVAIKIIDK----------QKTIDSGMEPRIIREIEAMR 74
Query: 234 ILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAAELSCA 293
L HPN++K+ K+YLV++Y GGELF L G L+E Y +L+ A
Sbjct: 75 RLHN--HPNVLKIHEVMATKSKIYLVVEYAAGGELFTKLIRFGRLNESAARRYFQQLASA 132
Query: 294 LKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVNQLYSIIG 353
L F H GI +RD+KP+N LL+++G+L ++DFGLS A PE N L++ G
Sbjct: 133 LSFCHRDGIAHRDVKPQNLLLDKQGNLKVSDFGLS--------ALPEHRSNNGLLHTACG 184
Query: 354 TPEYCAPEILAGEPYT-QNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQEKTGARI 412
TP Y APE++A Y D +S G ++ +L G PF N + KI K R
Sbjct: 185 TPAYTAPEVIAQRGYDGAKADAWSCGVFLFVLLAGYVPFDDANIVAMYRKI--HKRDYRF 242
Query: 413 PSYLSDGFKDYLGALLRKDPTKRWDVD 439
PS++S + + LL +P R ++
Sbjct: 243 PSWISKPARSIIYKLLDPNPETRMSIE 269
>At2g34650 [R] KOG0610 Putative serine/threonine protein kinase
Length = 438
Score = 126 bits (317), Expect = 8e-29
Identities = 83/269 (30%), Positives = 134/269 (48%), Gaps = 47/269 (17%)
Query: 213 IEKDANTTVEKRIERTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGEL--FY 270
++K+A ++K++ R E+TIL L+HP + L+ F +H +V++Y GG+L
Sbjct: 111 VDKEA-LALKKKMHRAEMEKTILKMLDHPFLPTLYAEFEASHFSCIVMEYCSGGDLHSLR 169
Query: 271 HLKEQGTLDEGTVAFYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKK 330
H + + FYAAE+ AL++LH GI+YRDLKPEN L+ GH++L+DF LS
Sbjct: 170 HRQPHRRFSLSSARFYAAEVLVALEYLHMLGIIYRDLKPENILVRSDGHIMLSDFDLSLC 229
Query: 331 S-----VFDDAATPEEGE--------NVNQLY---------------------------- 349
S V +++PE + + +L+
Sbjct: 230 SDSIAAVESSSSSPENQQLRSPRRFTRLARLFQRVLRSKKVQTLEPTRLFVAEPVTARSG 289
Query: 350 SIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKI--KQEK 407
S +GT EY APE+ +G + DW++ G +Y+M+ GK PF + +IL I +Q
Sbjct: 290 SFVGTHEYVAPEVASGGSHGNAVDWWAFGVFLYEMIYGKTPFVAPTNDVILRNIVKRQLS 349
Query: 408 TGARIPSYLSD-GFKDYLGALLRKDPTKR 435
P+ + + ++ + LL KDPTKR
Sbjct: 350 FPTDSPATMFELHARNLISGLLNKDPTKR 378
>CE02074 [T] KOG0986 G protein-coupled receptor kinase
Length = 727
Score = 126 bits (316), Expect = 1e-28
Identities = 91/281 (32%), Positives = 138/281 (48%), Gaps = 42/281 (14%)
Query: 167 LDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIE 226
++DF R +G G +G YAMK L K I +++ + +RI
Sbjct: 188 MNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRI-----KMKQGETLALNERIM 242
Query: 227 RTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFY 286
+ + + + P IV + Y+F KL +L + GG+L YHL + G E + FY
Sbjct: 243 LSL----VSTGQDCPFIVCMTYAFQSPDKLCFILDLMNGGDLHYHLSQHGVFTEQEMIFY 298
Query: 287 AAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGL----SKKSVFDDAATPEEG 342
A+E+ L+ +H++ +VYRDLKP N LL+E GH+ ++D GL SKK
Sbjct: 299 ASEVILGLEHMHNRFVVYRDLKPANILLDENGHVRVSDLGLACDYSKK------------ 346
Query: 343 ENVNQLYSIIGTPEYCAPEILA-GEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILN 401
+ ++ +GT Y APE+LA G Y + DW+SLGC++Y +L G PF HK +
Sbjct: 347 ----KPHASVGTHGYMAPEVLAKGVAYDSSADWFSLGCMLYKLLKGHSPFR--QHK---S 397
Query: 402 KIKQE------KTGARIPSY-LSDGFKDYLGALLRKDPTKR 435
K K E +P+ LS +D L LL++D R
Sbjct: 398 KDKNEIDKMTLTQDIELPNEGLSKDCRDLLEGLLKRDVPDR 438
>At3g23000 [T] KOG0583 Serine/threonine protein kinase
Length = 429
Score = 126 bits (316), Expect = 1e-28
Identities = 89/285 (31%), Positives = 140/285 (48%), Gaps = 24/285 (8%)
Query: 156 SSFSKTGAPRVLDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEK 215
SS + T A +L + R LG G++ A+K ++K +K
Sbjct: 11 SSPATTPAKILLGKYELGRRLGSGSFAKVHLARSIESDELVAVKIIEK----------KK 60
Query: 216 DANTTVEKRIERTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQ 275
+ +E RI R L HPNI+K+ K+YLV++ GGELF + +
Sbjct: 61 TIESGMEPRIIREIDAMRRLRH--HPNILKIHEVMATKSKIYLVMELASGGELFSKVLRR 118
Query: 276 GTLDEGTVAFYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDD 335
G L E T Y +L+ AL+F H G+ +RD+KP+N LL+E+G+L ++DFGLS
Sbjct: 119 GRLPESTARRYFQQLASALRFSHQDGVAHRDVKPQNLLLDEQGNLKVSDFGLS------- 171
Query: 336 AATPEEGENVNQLYSIIGTPEYCAPEILAGEPYT-QNCDWYSLGCLVYDMLIGKPPFTGV 394
A PE +N L++ GTP Y APE+++ Y D +S G +++ +L+G PF
Sbjct: 172 -ALPEHLQN-GLLHTACGTPAYTAPEVISRRGYDGAKADAWSCGVILFVLLVGDVPFDDS 229
Query: 395 NHKIILNKIKQEKTGARIPSYLSDGFKDYLGALLRKDPTKRWDVD 439
N + KI + R PS++S K + +L +P R ++
Sbjct: 230 NIAAMYRKI--HRRDYRFPSWISKQAKSIIYQMLDPNPVTRMSIE 272
>YPR111w [R] KOG0605 NDR and related serine/threonine kinases
Length = 564
Score = 125 bits (315), Expect = 1e-28
Identities = 80/275 (29%), Positives = 125/275 (45%), Gaps = 43/275 (15%)
Query: 169 DFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIERT 228
DF + +G+G YG A+K L K + ++
Sbjct: 168 DFQILTQVGQGGYGQVYLAKKKDSDEICALKILNKKLLFKLNET-------------NHV 214
Query: 229 FAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAA 288
ER IL+ +VKL Y+F D LYL ++++PGG+ L L G FY +
Sbjct: 215 LTERDILTTTRSDWLVKLLYAFQDPESLYLAMEFVPGGDFRTLLINTRILKSGHARFYIS 274
Query: 289 ELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATP-----EEGE 343
E+ CA+ LH G +RDLKPEN L++ GH+ LTDFGL+ +V ++ EE +
Sbjct: 275 EMFCAVNALHELGYTHRDLKPENFLIDATGHIKLTDFGLAAGTVSNERIESMKIRLEEVK 334
Query: 344 N-------------------------VNQLYSIIGTPEYCAPEILAGEPYTQNCDWYSLG 378
N +N S++G+P+Y A E+L G+ Y D++SLG
Sbjct: 335 NLEFPAFTERSIEDRRKIYHNMRKTEINYANSMVGSPDYMALEVLEGKKYDFTVDYWSLG 394
Query: 379 CLVYDMLIGKPPFTGVNHKIILNKIKQEKTGARIP 413
C++++ L+G PF+G + ++ K R P
Sbjct: 395 CMLFESLVGYTPFSGSSTNETYENLRYWKKTLRRP 429
>Hs4505831 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 496
Score = 125 bits (315), Expect = 1e-28
Identities = 107/387 (27%), Positives = 166/387 (42%), Gaps = 60/387 (15%)
Query: 168 DDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIER 227
+DF ++ +G GA+G +AMK L K E+L K A T +
Sbjct: 75 EDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEML-------KRAETACFRE--- 124
Query: 228 TFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHL-KEQGTLDEGTVAFY 286
ER +L ++ I L Y+F D++ LYLV+ Y GG+L L K + L E FY
Sbjct: 125 ---ERDVLVNGDNKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARFY 181
Query: 287 AAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVN 346
AE+ A+ +H V+RD+KP+N L++ GH+ L DFG K + D
Sbjct: 182 LAEMVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTV--------- 232
Query: 347 QLYSIIGTPEYCAPEILAGEP-----YTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILN 401
Q +GTP+Y +PEIL Y CDW+SLG +Y+ML G+ PF +
Sbjct: 233 QSSVAVGTPDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYG 292
Query: 402 KIKQEKTGARIPSYLSDGFKDYLGALLRKDPTKRWDVDKYWAQDGPXXXXXXXXXXXXXN 461
KI K + P+ ++D ++ + R ++ + + +D
Sbjct: 293 KIMNHKERFQFPAQVTDVSENAKDLIRRLICSREHRLGQNGIED---------------- 336
Query: 462 YIGHFIFRKIIWKQLLSGDLQKISVGPILPIITDWELAENFDTEFTEKRLDTSIYDNGIE 521
+ H F I W + + + P +P ++ NFD +D N
Sbjct: 337 FKKHPFFSGIDWDNIRNCE------APYIPEVSSPTDTSNFD-------VDDDCLKNSET 383
Query: 522 INNPRATKESAFAGSTDYFKGFSYVAS 548
+ P T AF+G F GF+Y +S
Sbjct: 384 MPPPTHT---AFSGHHLPFVGFTYTSS 407
>At3g12690 [R] KOG0610 Putative serine/threonine protein kinase
Length = 577
Score = 125 bits (315), Expect = 1e-28
Identities = 92/337 (27%), Positives = 147/337 (43%), Gaps = 71/337 (21%)
Query: 156 SSFSKTGAPRVLDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEK 215
+S + G LD+F ++ LG G G +AMK + KA +
Sbjct: 171 NSIASKGPQIGLDNFRLLKRLGYGDIGSVYLADLRGTNAVFAMKVMDKASL--------- 221
Query: 216 DANTTVEKRIERTFAERTILSQLEHPNIVKLFYSFHDNHKLY-LVLQYIPGGELFYHLKE 274
++ R ER ILS L+HP + L YS+ + K Y LV+++ GG L ++
Sbjct: 222 ----ASRNKLLRAQTEREILSLLDHPFLPTL-YSYFETDKFYCLVMEFCSGGNLHSLRQK 276
Query: 275 QGT--LDEGTVAFYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSV 332
Q + E FYA+E+ AL++LH G+VYRDLKPEN L+ + GH++L+DF LS +
Sbjct: 277 QPSRRFTEEAARFYASEVLLALEYLHMLGVVYRDLKPENILVRDEGHIMLSDFDLSLRCT 336
Query: 333 FDDAATPEE------GENVNQLYSI----------------------------------- 351
F+ G +N+ +++
Sbjct: 337 FNPTLVKSSSVCSGGGAILNEEFAVNGCMHPSAFLPRLLPSKKTRKAKSDSGLGGLSMPE 396
Query: 352 -------------IGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKI 398
+GT EY APEI+ GE + DW++ G +Y++L G PF G ++
Sbjct: 397 LMAEPTDVRSMSFVGTHEYLAPEIIRGEGHGSAVDWWTFGIFLYELLHGTTPFKGQGNRA 456
Query: 399 ILNKIKQEKTGARIPSYLSDGFKDYLGALLRKDPTKR 435
L+ + + ++S +D + LL KDP +R
Sbjct: 457 TLHNVVGQPLKFPDTPHVSSAARDLIRGLLVKDPHRR 493
>At3g06030 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 651
Score = 125 bits (315), Expect = 1e-28
Identities = 81/261 (31%), Positives = 134/261 (51%), Gaps = 17/261 (6%)
Query: 176 LGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIERTFAERTIL 235
+G GA+G A+KQ +LI+ S K+ + +E E +L
Sbjct: 74 IGCGAFGRVYMGMNLDSGELLAIKQ-----VLIAPSSASKEKTQGHIRELEE---EVQLL 125
Query: 236 SQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAAELSCALK 295
L HPNIV+ + ++ L ++++++PGG + L++ G+ E + Y +L L+
Sbjct: 126 KNLSHPNIVRYLGTVRESDSLNILMEFVPGGSISSLLEKFGSFPEPVIIMYTKQLLLGLE 185
Query: 296 FLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVNQLYSIIGTP 355
+LH+ GI++RD+K N L++ +G + L DFG SKK V E VN S+ GTP
Sbjct: 186 YLHNNGIMHRDIKGANILVDNKGCIRLADFGASKKVV--------ELATVNGAKSMKGTP 237
Query: 356 EYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKI-ILNKIKQEKTGARIPS 414
+ APE++ ++ + D +S+GC V +M GKPP++ + + I + K IP
Sbjct: 238 YWMAPEVILQTGHSFSADIWSVGCTVIEMATGKPPWSEQYQQFAAVLHIGRTKAHPPIPE 297
Query: 415 YLSDGFKDYLGALLRKDPTKR 435
LS KD+L L K+P+ R
Sbjct: 298 DLSPEAKDFLMKCLHKEPSLR 318
>At2g30360 [T] KOG0583 Serine/threonine protein kinase
Length = 435
Score = 125 bits (314), Expect = 2e-28
Identities = 84/269 (31%), Positives = 136/269 (50%), Gaps = 25/269 (9%)
Query: 174 RCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIERTFAERT 233
+ LG GA+ A+K L K ++L N + I+R E +
Sbjct: 25 KLLGCGAFAKVFHARDRRTGQSVAVKILNKKKLL---------TNPALANNIKR---EIS 72
Query: 234 ILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAAELSCA 293
I+ +L HPNIVKL K++ ++++ GGELF + + G L E Y +L A
Sbjct: 73 IMRRLSHPNIVKLHEVMATKSKIFFAMEFVKGGELFNKISKHGRLSEDLSRRYFQQLISA 132
Query: 294 LKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVNQLYSIIG 353
+ + H++G+ +RDLKPEN L++E G+L ++DFGL S D P+ L+++ G
Sbjct: 133 VGYCHARGVYHRDLKPENLLIDENGNLKVSDFGL---SALTDQIRPD-----GLLHTLCG 184
Query: 354 TPEYCAPEILAGEPYT-QNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQEKTGA-R 411
TP Y APEIL+ + Y D +S G +++ ++ G PF N ++N K+ G R
Sbjct: 185 TPAYVAPEILSKKGYEGAKVDVWSCGIVLFVLVAGYLPFNDPN---VMNMYKKIYKGEYR 241
Query: 412 IPSYLSDGFKDYLGALLRKDPTKRWDVDK 440
P ++S K ++ LL +P R +D+
Sbjct: 242 FPRWMSPDLKRFVSRLLDINPETRITIDE 270
>At2g25880 [D] KOG0580 Serine/threonine protein kinase
Length = 282
Score = 124 bits (312), Expect = 3e-28
Identities = 84/272 (30%), Positives = 129/272 (46%), Gaps = 26/272 (9%)
Query: 169 DFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIERT 228
DF + LG G +G A+K L KA++ S+ VE ++ R
Sbjct: 18 DFDIGKPLGRGKFGHVYLAREKRSDHIVALKVLFKAQLQQSQ----------VEHQLRR- 66
Query: 229 FAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAA 288
E I S L HPNI++L+ F+D ++YL+L+Y GEL+ L++ E A Y A
Sbjct: 67 --EVEIQSHLRHPNILRLYGYFYDQKRVYLILEYAVRGELYKELQKCKYFSERRAATYVA 124
Query: 289 ELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVNQL 348
L+ AL + H K +++RD+KPEN L+ +G L + DFG S N+
Sbjct: 125 SLARALIYCHGKHVIHRDIKPENLLIGAQGELKIADFGWSV-------------HTFNRR 171
Query: 349 YSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQEKT 408
++ GT +Y PE++ + + D +SLG L Y+ L G PPF H +I Q
Sbjct: 172 RTMCGTLDYLPPEMVESVEHDASVDIWSLGILCYEFLYGVPPFEAREHSETYKRIVQVDL 231
Query: 409 GARIPSYLSDGFKDYLGALLRKDPTKRWDVDK 440
+S KD + +L K+ T+R + K
Sbjct: 232 KFPPKPIVSSSAKDLISQMLVKESTQRLALHK 263
>YPL209c [D] KOG0580 Serine/threonine protein kinase
Length = 367
Score = 124 bits (311), Expect = 4e-28
Identities = 79/269 (29%), Positives = 133/269 (49%), Gaps = 26/269 (9%)
Query: 167 LDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIE 226
LDDF + LG+G +G A+K ++K EI+ ++K+
Sbjct: 101 LDDFELGKKLGKGKFGKVYCVRHRSTGYICALKVMEKEEII----------KYNLQKQFR 150
Query: 227 RTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFY 286
R E I + L HPN+ K + FHD ++YL+++Y+ GE++ L+ G ++ + Y
Sbjct: 151 R---EVEIQTSLNHPNLTKSYGYFHDEKRVYLLMEYLVNGEMYKLLRLHGPFNDILASDY 207
Query: 287 AAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVN 346
+++ AL ++H K I++RD+KPEN L+ + LTDFG S P E N
Sbjct: 208 IYQIANALDYMHKKNIIHRDIKPENILIGFNNVIKLTDFGWS-------IINPPE----N 256
Query: 347 QLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQE 406
+ ++ GT +Y +PE++ Y D ++LG L +++L G PPF +I
Sbjct: 257 RRKTVCGTIDYLSPEMVESREYDHTIDAWALGVLAFELLTGAPPFEEEMKDTTYKRI--A 314
Query: 407 KTGARIPSYLSDGFKDYLGALLRKDPTKR 435
++PS +S +D + LL+ DP R
Sbjct: 315 ALDIKMPSNISQDAQDLILKLLKYDPKDR 343
>CE17284 [T] KOG0583 Serine/threonine protein kinase
Length = 726
Score = 124 bits (311), Expect = 4e-28
Identities = 79/224 (35%), Positives = 119/224 (52%), Gaps = 14/224 (6%)
Query: 225 IERTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVA 284
+ R E L L H NI +L++ K ++V++Y GGE+F ++ + L+E
Sbjct: 51 LPRVQTEMDALRNLSHQNICRLYHYIETEDKFFIVMEYCSGGEMFDYIVRKERLEESEAR 110
Query: 285 FYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGE- 343
+ +L A+ F+HS+G +RDLKPEN LL E HL L DFGL K+ E+G
Sbjct: 111 HFFRQLVSAIAFVHSQGYAHRDLKPENLLLTEDLHLKLIDFGLCAKT--------EKGRI 162
Query: 344 NVNQLYSIIGTPEYCAPEILAGEPYTQN-CDWYSLGCLVYDMLIGKPPFTGVNHKIILNK 402
+ + L + G+P Y APE++ G Y N D +S+G L+Y +L+G PF N +I+ K
Sbjct: 163 DKHNLDTCCGSPAYAAPELIQGLQYKGNEADVWSMGILLYTLLVGALPFEDDNMQIMYKK 222
Query: 403 IKQEKTGARI-PSYLSDGFKDYLGALLRKDPTKRWDVDKYWAQD 445
I ++G P +LS K L A+L+ P +R V K D
Sbjct: 223 I---QSGCFYEPEFLSPLSKQLLRAMLQVVPERRISVKKLLEHD 263
>Hs16357474_1 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1530
Score = 124 bits (311), Expect = 4e-28
Identities = 87/257 (33%), Positives = 122/257 (46%), Gaps = 28/257 (10%)
Query: 168 DDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIER 227
+DF I+ +G GA+G YAMK L K E+L K A T +
Sbjct: 74 EDFEIIKVIGRGAFGEVAVVKMKNTERIYAMKILNKWEML-------KRAETACFRE--- 123
Query: 228 TFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHL-KEQGTLDEGTVAFY 286
ER +L + I L Y+F D + LYLV+ Y GG+L L K + L E FY
Sbjct: 124 ---ERDVLVNGDCQWITALHYAFQDENHLYLVMDYYVGGDLLTLLSKFEDKLPEDMARFY 180
Query: 287 AAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVN 346
E+ A+ +H V+RD+KP+N LL+ GH+ L DFG K + DD
Sbjct: 181 IGEMVLAIDSIHQLHYVHRDIKPDNVLLDVNGHIRLADFGSCLK-MNDDGTV-------- 231
Query: 347 QLYSIIGTPEYCAPEILAG-----EPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILN 401
Q +GTP+Y +PEIL Y CDW+SLG +Y+ML G+ PF +
Sbjct: 232 QSSVAVGTPDYISPEILQAMEDGMGKYGPECDWWSLGVCMYEMLYGETPFYAESLVETYG 291
Query: 402 KIKQEKTGARIPSYLSD 418
KI + + PS+++D
Sbjct: 292 KIMNHEERFQFPSHVTD 308
>At3g01090 [T] KOG0583 Serine/threonine protein kinase
Length = 512
Score = 124 bits (310), Expect = 5e-28
Identities = 85/279 (30%), Positives = 142/279 (50%), Gaps = 29/279 (10%)
Query: 159 SKTGAPRVLDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDAN 218
S++G +L ++ R LG G++G A+K L + +I N
Sbjct: 8 SRSGVESILPNYKLGRTLGIGSFGRVKIAEHALTGHKVAIKILNRRKI----------KN 57
Query: 219 TTVEKRIERTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTL 278
+E+++ R E IL HP+I++L+ +YLV++Y+ GELF ++ E+G L
Sbjct: 58 MEMEEKVRR---EIKILRLFMHPHIIRLYEVIETPTDIYLVMEYVNSGELFDYIVEKGRL 114
Query: 279 DEGTVAFYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAAT 338
E + ++ +++ H +V+RDLKPEN LL+ + ++ + DFGLS ++ D
Sbjct: 115 QEDEARNFFQQIISGVEYCHRNMVVHRDLKPENLLLDSKCNVKIADFGLS--NIMRDG-- 170
Query: 339 PEEGENVNQLYSIIGTPEYCAPEILAGEPYT-QNCDWYSLGCLVYDMLIGKPPFTGVNHK 397
+ L + G+P Y APE+++G+ Y D +S G ++Y +L G PF N
Sbjct: 171 -------HFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYALLCGTLPFDDEN-- 221
Query: 398 IILNKIKQEKTGA-RIPSYLSDGFKDYLGALLRKDPTKR 435
I N K+ K G +PS+LS G +D + +L DP KR
Sbjct: 222 -IPNLFKKIKGGIYTLPSHLSPGARDLIPRMLVVDPMKR 259
>At2g25090 [T] KOG0583 Serine/threonine protein kinase
Length = 469
Score = 124 bits (310), Expect = 5e-28
Identities = 85/263 (32%), Positives = 125/263 (47%), Gaps = 16/263 (6%)
Query: 174 RCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIERTFAERT 233
R LG G + A+K +KK + +E+ IER A
Sbjct: 19 RLLGTGNFAKVYHGTEISTGDDVAIKVIKKDHVFKRRGMMEQ---------IEREIA--- 66
Query: 234 ILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAAELSCA 293
++ L HPN+V+L K++ V++Y+ GGELF + G L E Y +L A
Sbjct: 67 VMRLLRHPNVVELREVMATKKKIFFVMEYVNGGELFEMIDRDGKLPEDLARKYFQQLISA 126
Query: 294 LKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVNQLYSIIG 353
+ F HS+G+ +RD+KPEN LL+ G L +TDFGLS + + G + + L++ G
Sbjct: 127 VDFCHSRGVFHRDIKPENLLLDGEGDLKVTDFGLS-ALMMPEGLGGRRGSSDDLLHTRCG 185
Query: 354 TPEYCAPEILAGEPYT-QNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQEKTGARI 412
TP Y APE+L + Y D +S G ++Y +L G PF N + KI K
Sbjct: 186 TPAYVAPEVLRNKGYDGAMADIWSCGIVLYALLAGFLPFIDENVMTLYTKI--FKAECEF 243
Query: 413 PSYLSDGFKDYLGALLRKDPTKR 435
P + S K+ L LL DP +R
Sbjct: 244 PPWFSLESKELLSRLLVPDPEQR 266
>CE11916 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1548
Score = 123 bits (309), Expect = 6e-28
Identities = 112/389 (28%), Positives = 163/389 (41%), Gaps = 66/389 (16%)
Query: 168 DDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIER 227
DDF ++ +G+GA+G YAMK L K E++ K A T +
Sbjct: 81 DDFEVLKVIGKGAFGEVAVVRMRGVGEIYAMKILNKWEMV-------KRAETACFRE--- 130
Query: 228 TFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHL-KEQGTLDEGTVAFY 286
ER +L + I L Y+F D LY V+ Y GG++ L K + E FY
Sbjct: 131 ---ERDVLVYGDRRWITNLHYAFQDEKNLYFVMDYYIGGDMLTLLSKFVDHIPESMAKFY 187
Query: 287 AAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVN 346
AE+ A+ LH G V+RD+KP+N LL+ +GH+ L DFG + + D + NV
Sbjct: 188 IAEMVLAIDSLHRLGYVHRDVKPDNVLLDMQGHIRLADFGSCLRILADGSV----ASNV- 242
Query: 347 QLYSIIGTPEYCAPEILAGEP-----YTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILN 401
+GTP+Y +PEIL Y + CDW+SLG +Y+ML G PF
Sbjct: 243 ----AVGTPDYISPEILRAMEDGRGRYGKECDWWSLGICMYEMLYGTTPFYSERLVDTYG 298
Query: 402 KIKQEKTGARIPS-----YLSDGFKDYLGALLRKDPTKRWDVDKYWAQDGPXXXXXXXXX 456
KI + P +S+ KD + L+ D + ++G
Sbjct: 299 KIMSHQDMLDFPDDEIDWVVSEEAKDLIRQLICSS-------DVRFGRNG---------- 341
Query: 457 XXXXNYIGHFIFRKIIWKQLLSGDLQKISVGPILPIITDWELAENFDTEFTEKRLDTSIY 516
++ H F I W + + S P +P ++ E NFD + E
Sbjct: 342 --LSDFQLHPFFEGIDWNTI------RDSNPPYVPEVSSPEDTSNFDVDVCEDDF----- 388
Query: 517 DNGIEINNPRATKESAFAGSTDYFKGFSY 545
E PR +AF G+ F GFSY
Sbjct: 389 -TPCETQPPRVL--AAFTGNHLPFVGFSY 414
>CE28218 [D] KOG0588 Serine/threonine protein kinase
Length = 914
Score = 123 bits (308), Expect = 8e-28
Identities = 79/266 (29%), Positives = 137/266 (50%), Gaps = 28/266 (10%)
Query: 174 RCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIERTFAERT 233
+ LG+G G A+K + K ++ + +V +++ER A
Sbjct: 51 KTLGKGQTGLVKTGTHCITGRKVAIKIVNKEKL-----------SESVLQKVEREIA--- 96
Query: 234 ILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAAELSCA 293
I+ +EHP+++ L+ + + LYL+L+++ GGELF +L +G L + ++ A
Sbjct: 97 IMKLIEHPHVLHLYDVYENKKYLYLLLEHVSGGELFDYLVRKGRLMSKEARKFFRQIISA 156
Query: 294 LKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVNQLYSIIG 353
L F H+ I +RDLKPEN LL+ER ++ + DFG++ V EG + L + G
Sbjct: 157 LDFCHAHNICHRDLKPENLLLDERNNIKVADFGMASLQV--------EG---SMLETSCG 205
Query: 354 TPEYCAPEILAGEPYT-QNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQEKTGARI 412
+P Y PE++ GE Y + D +S G ++Y +L+G PF N + +L K+K + I
Sbjct: 206 SPHYACPEVIRGEKYDGRKADVWSCGVILYALLVGALPFDDDNLRNLLEKVK--RGVFHI 263
Query: 413 PSYLSDGFKDYLGALLRKDPTKRWDV 438
P ++ + L A++ DP KR+ +
Sbjct: 264 PHFVPADVQSLLRAMIEVDPGKRYSL 289
>Hs9845489 [R] KOG0586 Serine/threonine protein kinase
Length = 691
Score = 122 bits (307), Expect = 1e-27
Identities = 74/217 (34%), Positives = 116/217 (53%), Gaps = 14/217 (6%)
Query: 225 IERTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVA 284
+++ F E I+ L HPNIVKLF LYLV++Y GGE+F +L G + E
Sbjct: 61 LQKLFREVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEAR 120
Query: 285 FYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGEN 344
++ A+++ H K IV+RDLK EN LL+ ++ + DFG S + F
Sbjct: 121 AKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFG---------- 170
Query: 345 VNQLYSIIGTPEYCAPEILAGEPYT-QNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKI 403
N+L + G+P Y APE+ G+ Y D +SLG ++Y ++ G PF G N K + ++
Sbjct: 171 -NKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERV 229
Query: 404 KQEKTGARIPSYLSDGFKDYLGALLRKDPTKRWDVDK 440
+ K RIP Y+S ++ L L +P+KR +++
Sbjct: 230 LRGK--YRIPFYMSTDCENLLKKFLILNPSKRGTLEQ 264
>Hs9845487 [R] KOG0586 Serine/threonine protein kinase
Length = 745
Score = 122 bits (307), Expect = 1e-27
Identities = 74/217 (34%), Positives = 116/217 (53%), Gaps = 14/217 (6%)
Query: 225 IERTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVA 284
+++ F E I+ L HPNIVKLF LYLV++Y GGE+F +L G + E
Sbjct: 61 LQKLFREVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEAR 120
Query: 285 FYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGEN 344
++ A+++ H K IV+RDLK EN LL+ ++ + DFG S + F
Sbjct: 121 AKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFG---------- 170
Query: 345 VNQLYSIIGTPEYCAPEILAGEPYT-QNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKI 403
N+L + G+P Y APE+ G+ Y D +SLG ++Y ++ G PF G N K + ++
Sbjct: 171 -NKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERV 229
Query: 404 KQEKTGARIPSYLSDGFKDYLGALLRKDPTKRWDVDK 440
+ K RIP Y+S ++ L L +P+KR +++
Sbjct: 230 LRGK--YRIPFYMSTDCENLLKKFLILNPSKRGTLEQ 264
>Hs22062450 [R] KOG0586 Serine/threonine protein kinase
Length = 787
Score = 122 bits (307), Expect = 1e-27
Identities = 74/217 (34%), Positives = 116/217 (53%), Gaps = 14/217 (6%)
Query: 225 IERTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVA 284
+++ F E I+ L HPNIVKLF LYLV++Y GGE+F +L G + E
Sbjct: 94 LQKLFREVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEAR 153
Query: 285 FYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGEN 344
++ A+++ H K IV+RDLK EN LL+ ++ + DFG S + F
Sbjct: 154 AKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFG---------- 203
Query: 345 VNQLYSIIGTPEYCAPEILAGEPYT-QNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKI 403
N+L + G+P Y APE+ G+ Y D +SLG ++Y ++ G PF G N K + ++
Sbjct: 204 -NKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERV 262
Query: 404 KQEKTGARIPSYLSDGFKDYLGALLRKDPTKRWDVDK 440
+ K RIP Y+S ++ L L +P+KR +++
Sbjct: 263 LRGK--YRIPFYMSTDCENLLKKFLILNPSKRGTLEQ 297
>Hs14728804 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 576
Score = 122 bits (307), Expect = 1e-27
Identities = 87/271 (32%), Positives = 129/271 (47%), Gaps = 36/271 (13%)
Query: 174 RCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIERTFAERT 233
R +G+G + YAMK + K+ + ED ++ +E
Sbjct: 288 RVIGDGNFAVVKECRHRETRQAYAMKIIDKSRLKGKEDMVD---------------SEIL 332
Query: 234 ILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAAELSCA 293
I+ L HPNIVKL + + ++YL+L+Y+ GG+LF + E E A +L A
Sbjct: 333 IIQSLSHPNIVKLHEVYETDMEIYLILEYVQGGDLFDAIIESVKFPEPDAALMIMDLCKA 392
Query: 294 LKFLHSKGIVYRDLKPENCLL----NERGHLVLTDFGLSKKSVFDDAATPEEGENVNQLY 349
L +H K IV+RDLKPEN L+ ++ L L DFGL+K V ++
Sbjct: 393 LVHMHDKSIVHRDLKPENLLVQRNEDKSTTLKLADFGLAK-------------HVVRPIF 439
Query: 350 SIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNH-KIILNKIKQEKT 408
++ GTP Y APEIL+ + Y D ++ G ++Y +L G PPF + L I Q
Sbjct: 440 TVCGTPTYVAPEILSEKGYGLEVDMWAAGVILYILLCGFPPFRSPERDQDELFNIIQLGH 499
Query: 409 GARIPSY---LSDGFKDYLGALLRKDPTKRW 436
+P Y +SD KD + LL DP KR+
Sbjct: 500 FEFLPPYWDNISDAAKDLVSRLLVVDPKKRY 530
>At5g39440 [T] KOG0583 Serine/threonine protein kinase
Length = 494
Score = 122 bits (306), Expect = 1e-27
Identities = 78/262 (29%), Positives = 134/262 (50%), Gaps = 26/262 (9%)
Query: 174 RCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIERTFAERT 233
+ LG G++ A+K L +++I N +E +++R E
Sbjct: 23 KTLGHGSFAKVKLALHVATGHKVAIKILNRSKI----------KNMGIEIKVQR---EIK 69
Query: 234 ILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAAELSCA 293
IL L HP+I++ + + +Y+V++Y+ GELF ++ E+G L E ++
Sbjct: 70 ILRFLMHPHIIRQYEVIETPNDIYVVMEYVKSGELFDYIVEKGKLQEDEARHLFQQIISG 129
Query: 294 LKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVNQLYSIIG 353
+++ H IV+RDLKPEN LL+ + ++ + DFGLS +V D + L + G
Sbjct: 130 VEYCHRNMIVHRDLKPENVLLDSQCNIKIVDFGLS--NVMHDG---------HFLKTSCG 178
Query: 354 TPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQEKTGARIP 413
+P Y APE+++G+PY + D +S G ++Y +L G PF N + KIK+ +P
Sbjct: 179 SPNYAAPEVISGKPYGPDVDIWSCGVILYALLCGTLPFDDENIPNVFEKIKRGM--YTLP 236
Query: 414 SYLSDGFKDYLGALLRKDPTKR 435
++LS +D + +L DPT R
Sbjct: 237 NHLSHFARDLIPRMLMVDPTMR 258
>At5g35410 [T] KOG0583 Serine/threonine protein kinase
Length = 446
Score = 122 bits (306), Expect = 1e-27
Identities = 82/263 (31%), Positives = 132/263 (50%), Gaps = 26/263 (9%)
Query: 174 RCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIERTFAERT 233
R +GEG + A+K + K+ IL + + +++ E +
Sbjct: 15 RTIGEGTFAKVKFARNTDTGDNVAIKIMAKSTILKN-------------RMVDQIKREIS 61
Query: 234 ILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAAELSCA 293
I+ + HPNIV+L+ K+Y+VL+++ GGELF + +G L+E Y +L A
Sbjct: 62 IMKIVRHPNIVRLYEVLASPSKIYIVLEFVTGGELFDRIVHKGRLEESESRKYFQQLVDA 121
Query: 294 LKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVNQLYSIIG 353
+ H KG+ +RDLKPEN LL+ G+L ++DFGLS A P+EG V L + G
Sbjct: 122 VAHCHCKGVYHRDLKPENLLLDTNGNLKVSDFGLS--------ALPQEG--VELLRTTCG 171
Query: 354 TPEYCAPEILAGEPYTQN-CDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQEKTGARI 412
TP Y APE+L+G+ Y + D +S G +++ +L G PF+ + + KI +
Sbjct: 172 TPNYVAPEVLSGQGYDGSAADIWSCGVILFVILAGYLPFSETDLPGLYRKINAAEFSC-- 229
Query: 413 PSYLSDGFKDYLGALLRKDPTKR 435
P + S K + +L +P R
Sbjct: 230 PPWFSAEVKFLIHRILDPNPKTR 252
>CE07156 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 392
Score = 122 bits (305), Expect = 2e-27
Identities = 86/315 (27%), Positives = 148/315 (46%), Gaps = 47/315 (14%)
Query: 167 LDDFVPIRCLGEGAYGXXXXXXXXX---XXXXYAMKQLKKAEILISEDSIEKDANTTVEK 223
++DF ++ +G GAYG YAMK ++K + +D +E
Sbjct: 26 IEDFEILKHIGSGAYGEVAAVRKLNGCDTETIYAMKVMEKRRMSKHKDMVEH-------- 77
Query: 224 RIERTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTV 283
E IL+ + +P +K+ YSF L V+ + GG++ ++ + ++E +
Sbjct: 78 -------EWKILTTIHNPFFMKMSYSFQTKRHLVFVMPFAGGGDMLTMMENECLIEE-SA 129
Query: 284 AFYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGE 343
FY EL + +LH K IV+RD+K EN L+ GHL++TD+GLS AT + E
Sbjct: 130 HFYLCELVEGIGYLHEKHIVHRDVKLENLLIGNDGHLMITDYGLS--------ATGCDAE 181
Query: 344 NVNQLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKI 403
+ Q +IGT APE+ + Y +CDW+++G DM K F G + K +
Sbjct: 182 DAIQ--GVIGTRHTMAPEVHLEKKYGTSCDWWAVGITYCDMRSDKAVFDGADSKEYSDST 239
Query: 404 KQEKTGARIPSYLSDGFKDYLGALLRKDPTKRWDVDKYWAQDGPXXXXXXXXXXXXXNYI 463
+++ R+P LS + ++ L+ +DPT+R +GP
Sbjct: 240 AKKR--PRLPKVLSPRERGFVNKLIVRDPTQR-------LGNGPDGTATVK--------- 281
Query: 464 GHFIFRKIIWKQLLS 478
H +F+ ++W+ +L+
Sbjct: 282 AHDMFKGVVWEDVLA 296
>SPBC21.06c [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 1062
Score = 121 bits (304), Expect = 2e-27
Identities = 77/261 (29%), Positives = 131/261 (49%), Gaps = 27/261 (10%)
Query: 175 CLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIERTFAERTI 234
CLG+GA+G A+K++K +++L S+ S+ K E +
Sbjct: 14 CLGKGAFGAVYRGLNIKNGETVAVKKVKLSKMLKSDLSVIK--------------MEIDL 59
Query: 235 LSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAAELSCAL 294
L L+HPNIVK S+ N L ++L+Y G L K G + E VA Y ++ L
Sbjct: 60 LKNLDHPNIVKYRGSYQTNDSLCIILEYCENGSLRSICKNFGKIPENLVALYTFQVLQGL 119
Query: 295 KFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVNQLYSIIGT 354
+LH++G+++RD+K N L + G + L DFG++ K N + +S++G+
Sbjct: 120 LYLHNQGVIHRDIKGANILTTKDGTIKLADFGVATKI------------NALEDHSVVGS 167
Query: 355 PEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQEKTGARIPS 414
P + APE++ T D +S+GC V ++L G PP+ ++ L ++ +++ +PS
Sbjct: 168 PYWMAPEVIELVGATTASDIWSVGCTVIELLDGNPPYYDLDPTSALFRMVKDE-HPPLPS 226
Query: 415 YLSDGFKDYLGALLRKDPTKR 435
+S K +L +KDP R
Sbjct: 227 NISSAAKSFLMQCFQKDPNLR 247
>7293666 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 576
Score = 121 bits (304), Expect = 2e-27
Identities = 73/210 (34%), Positives = 113/210 (53%), Gaps = 12/210 (5%)
Query: 226 ERTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAF 285
E+T E TI L HPNIVK F D+ +Y+VL+ + K + ++ E +
Sbjct: 68 EKTAQEITIHRSLNHPNIVKFHNYFEDSQNIYIVLELCKKRSMMELHKRRKSITEFECRY 127
Query: 286 YAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENV 345
Y ++ +K+LH I++RDLK N LN+ H+ + DFGL+ + + EGE
Sbjct: 128 YIYQIIQGVKYLHDNRIIHRDLKLGNLFLNDLLHVKIGDFGLATRIEY-------EGERK 180
Query: 346 NQLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQ 405
++ GTP Y APEIL + ++ D +S+GC++Y +L+G+PPF K +KIK
Sbjct: 181 K---TLCGTPNYIAPEILTKKGHSFEVDIWSIGCVMYTLLVGQPPFETKTLKDTYSKIK- 236
Query: 406 EKTGARIPSYLSDGFKDYLGALLRKDPTKR 435
K R+PSYL D + A+L+ +P R
Sbjct: 237 -KCEYRVPSYLRKPAADMVIAMLQPNPESR 265
>7293496 [R] KOG0597 Serine-threonine protein kinase FUSED
Length = 805
Score = 121 bits (304), Expect = 2e-27
Identities = 72/213 (33%), Positives = 113/213 (52%), Gaps = 13/213 (6%)
Query: 223 KRIERTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGT 282
K ++ E I ++L+HP+++++ SF L++V ++ +L +L G + E
Sbjct: 43 KELKNLRRECDIQARLKHPHVIEMIESFESKTDLFVVTEFALM-DLHRYLSYNGAMGEEP 101
Query: 283 VAFYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEG 342
L AL +LHS I++RDLKP+N LL++ H L DFGL++
Sbjct: 102 ARRVTGHLVSALYYLHSNRILHRDLKPQNVLLDKNMHAKLCDFGLARNMTL--------- 152
Query: 343 ENVNQLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNK 402
+ L SI GTP Y APE+LA +PY + D +SLGC+ Y+ + G+PPF + ++
Sbjct: 153 -GTHVLTSIKGTPLYMAPELLAEQPYDHHADMWSLGCIAYESMAGQPPFCASSILHLVKM 211
Query: 403 IKQEKTGARIPSYLSDGFKDYLGALLRKDPTKR 435
IK E + PS L+ + +L LL KDP R
Sbjct: 212 IKHE--DVKWPSTLTSECRSFLQGLLEKDPGLR 242
>7299438 [R] KOG0586 Serine/threonine protein kinase
Length = 705
Score = 121 bits (303), Expect = 3e-27
Identities = 82/264 (31%), Positives = 129/264 (48%), Gaps = 28/264 (10%)
Query: 173 IRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIERTFAER 232
I+ LG+G + A+K + K ++ NT+ +++ R E
Sbjct: 101 IKTLGKGNFAKVKLAIHVPTGREVAIKVIDKTQL-----------NTSARQKLYR---EV 146
Query: 233 TILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAAELSC 292
I+ L HPNIV+LF LYLV++Y GELF HL + G + E +L
Sbjct: 147 KIMKLLNHPNIVRLFQVIESERTLYLVMEYASRGELFDHLVKNGRMRERDARVIFRQLVS 206
Query: 293 ALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVNQLYSII 352
A+++ HSK +V+RDLK EN LL++ ++ + DFG + FD A QL +
Sbjct: 207 AIQYCHSKFVVHRDLKAENLLLDQHMNIKIADFGFG--NTFDPNA---------QLETFC 255
Query: 353 GTPEYCAPEILAGEPYT-QNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQEKTGAR 411
G+P Y APE+ G Y D +SLG ++Y ++ G PF G K + ++ + K R
Sbjct: 256 GSPPYAAPELFMGRKYAGPEVDAWSLGVVLYTLVSGSLPFDGGTLKELRERVLRGK--YR 313
Query: 412 IPSYLSDGFKDYLGALLRKDPTKR 435
+P Y+S ++ + L +P KR
Sbjct: 314 VPYYISMDCENLMRKFLVLNPAKR 337
>At1g50230 [R] KOG0597 Serine-threonine protein kinase FUSED
Length = 269
Score = 120 bits (302), Expect = 4e-27
Identities = 84/270 (31%), Positives = 138/270 (51%), Gaps = 29/270 (10%)
Query: 167 LDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIE 226
++D+ I +GEG++G AMK + K + +KD ++ + + IE
Sbjct: 3 VEDYHVIELVGEGSFGRVYKGRRKYTGQTVAMKFIMK------QGKTDKDIHS-LRQEIE 55
Query: 227 RTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFY 286
IL +L+H NI+++ SF +N + + V+ GELF L++ L E V
Sbjct: 56 -------ILRKLKHENIIEMLDSF-ENAREFCVVTEFAQGELFEILEDDKCLPEEQVQAI 107
Query: 287 AAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVN 346
A +L AL +LHS I++RD+KP+N L+ + L DFG ++ N
Sbjct: 108 AKQLVKALDYLHSNRIIHRDMKPQNILIGAGSVVKLCDFGFARAM----------STNTV 157
Query: 347 QLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPF-TGVNHKIILNKIKQ 405
L SI GTP Y APE++ +PY + D +SLG ++Y++ +G+PPF T + +I + +K
Sbjct: 158 VLRSIKGTPLYMAPELVKEQPYDRTVDLWSLGVILYELYVGQPPFYTNSVYALIRHIVKD 217
Query: 406 EKTGARIPSYLSDGFKDYLGALLRKDPTKR 435
+ P +S F+ +L LL K+P R
Sbjct: 218 P---VKYPDEMSTYFESFLKGLLNKEPHSR 244
>Hs8923922 [R] KOG0586 Serine/threonine protein kinase
Length = 795
Score = 120 bits (301), Expect = 5e-27
Identities = 74/217 (34%), Positives = 115/217 (52%), Gaps = 14/217 (6%)
Query: 225 IERTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVA 284
+++ F E I+ L HPNIVKLF LYLV++Y GGE+F +L G + E
Sbjct: 101 LQKLFREVRIMKILNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEAR 160
Query: 285 FYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGEN 344
++ A+++ H K IV+RDLK EN LL+ ++ + DFG S +
Sbjct: 161 AKFRQIVSAVQYCHQKYIVHRDLKAENLLLDGDMNIKIADFGFSNEFTVG---------- 210
Query: 345 VNQLYSIIGTPEYCAPEILAGEPYT-QNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKI 403
N+L + G+P Y APE+ G+ Y D +SLG ++Y ++ G PF G N K + ++
Sbjct: 211 -NKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERV 269
Query: 404 KQEKTGARIPSYLSDGFKDYLGALLRKDPTKRWDVDK 440
+ K RIP Y+S ++ L LL +P KR +++
Sbjct: 270 LRGK--YRIPFYMSTDCENLLKKLLVLNPIKRGSLEQ 304
>Hs20545245 [D] KOG0588 Serine/threonine protein kinase
Length = 795
Score = 120 bits (301), Expect = 5e-27
Identities = 70/222 (31%), Positives = 122/222 (54%), Gaps = 17/222 (7%)
Query: 220 TVEKRIERTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLD 279
+V ++ER A IL +EHP+++KL + + LYLVL+++ GGELF +L ++G L
Sbjct: 90 SVLMKVEREIA---ILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLT 146
Query: 280 EGTVAFYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATP 339
+ ++ AL F HS I +RDLKPEN LL+E+ ++ + DFG++ V D
Sbjct: 147 PKEARKFFRQIVSALDFCHSYSICHRDLKPENLLLDEKNNIRIADFGMASLQVGD----- 201
Query: 340 EEGENVNQLYSIIGTPEYCAPEILAGEPYT-QNCDWYSLGCLVYDMLIGKPPFTGVNHKI 398
+ L + G+P Y PE++ GE Y + D +S G +++ +L+G PF N +
Sbjct: 202 ------SLLETSCGSPHYACPEVIKGEKYDGRRADMWSCGVILFALLVGALPFDDDNLRQ 255
Query: 399 ILNKIKQEKTGARIPSYLSDGFKDYLGALLRKDPTKRWDVDK 440
+L K+K + +P ++ + L ++ +P KR +++
Sbjct: 256 LLEKVK--RGVFHMPHFIPPDCQSLLRGMIEVEPEKRLSLEQ 295
>At5g25110 [T] KOG0583 Serine/threonine protein kinase
Length = 460
Score = 120 bits (301), Expect = 5e-27
Identities = 86/263 (32%), Positives = 132/263 (49%), Gaps = 25/263 (9%)
Query: 174 RCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIERTFAERT 233
R LG+G +G A+K +I++D +++ E +E+ E +
Sbjct: 19 RLLGKGTFGKVYYGKEITTGESVAIK-------IINKDQVKR------EGMMEQIKREIS 65
Query: 234 ILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAAELSCA 293
I+ + HPNIV+L K++ +++Y+ GGELF + + G L E + Y +L A
Sbjct: 66 IMRLVRHPNIVELKEVMATKTKIFFIMEYVKGGELFSKIVK-GKLKEDSARKYFQQLISA 124
Query: 294 LKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVNQLYSIIG 353
+ F HS+G+ +RDLKPEN L++E G L ++DFGLS A PE+ L++ G
Sbjct: 125 VDFCHSRGVSHRDLKPENLLVDENGDLKVSDFGLS--------ALPEQILQDGLLHTQCG 176
Query: 354 TPEYCAPEILAGEPYT-QNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQEKTGARI 412
TP Y APE+L + Y D +S G ++Y +L G PF N + KI K+
Sbjct: 177 TPAYVAPEVLRKKGYDGAKGDIWSCGIILYVLLAGFLPFQDENLMKMYRKI--FKSEFEY 234
Query: 413 PSYLSDGFKDYLGALLRKDPTKR 435
P + S K + LL DP KR
Sbjct: 235 PPWFSPESKRLISKLLVVDPNKR 257
>SPCC297.03 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kinase beta
and related serine/threonine protein kinases
Length = 652
Score = 120 bits (300), Expect = 7e-27
Identities = 103/402 (25%), Positives = 184/402 (45%), Gaps = 39/402 (9%)
Query: 51 LHKNQFR--MDLSALPPNTYEEEAL------ISDTEEQAEMMSG-FLVPPDSGESKQSQT 101
L KN + +D S +PP+ + E + SD+ + +G +++ P GE
Sbjct: 18 LRKNTWHPEVDDSEVPPSVFPEYPVHKAIQKTSDSFRKRNYSAGDYVIAPLGGE------ 71
Query: 102 KEPARRRSSLYNKFVVNPAQHTIRLSLNAQGDSDKETRDVLSVSSVEETRQLRASSFSKT 161
R SSL + + P +H RL + ++ ++ + + V+ET+++R F +
Sbjct: 72 ----REGSSLTHSWTFQPGKHNQRLYSDNFQEAQRQWKRLQEWGEVKETKKIR-KRFDRF 126
Query: 162 GAPRVLDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTV 221
+ ++ + I+ LG G +G A+K + K E K
Sbjct: 127 SGRKYINHYEIIKELGRGMHGKVKLGRDTVTRELLAIKIIPKTE------RRPKLGRANA 180
Query: 222 EKRIERTFAERTILSQLEHPNIVKLFYSFHD--NHKLYLVLQYIPGGELFYHLKEQGTLD 279
+ E+ E IL + HPN+V+L D + K+YLVL+Y+ GGE+ + + L
Sbjct: 181 SSQKEKVRREIAILKKCVHPNVVRLREVIDDPSSTKVYLVLEYMSGGEVPWTDCDSPVLS 240
Query: 280 EGTVAFYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATP 339
Y ++ L++LH +GI++RD+KP N LLN + ++DFG+ S +A
Sbjct: 241 ISEARQYFRDVVLGLEYLHYQGIIHRDIKPANLLLNSSNCVKISDFGV---SYIANAGLN 297
Query: 340 EEGENVNQLYSIIGTPEYCAPEILAGE------PYTQNCDWYSLGCLVYDMLIGKPPFTG 393
E +N +L +GTP + APE+ + ++ D ++LG ++ +L G+ PF
Sbjct: 298 E--DNDVELAKTVGTPAFFAPELCWTDLDRPRPKISEAIDVWALGVTLFCLLFGRCPFNA 355
Query: 394 VNHKIILNKIKQEKTGARIPSYLSDGFKDYLGALLRKDPTKR 435
+ +KI E+ + + +D L LL KDP +R
Sbjct: 356 SMEYELFDKIVNERLNIPSTPDIGEEGRDLLKRLLCKDPEQR 397
>At3g29160 [T] KOG0583 Serine/threonine protein kinase
Length = 512
Score = 120 bits (300), Expect = 7e-27
Identities = 83/283 (29%), Positives = 140/283 (49%), Gaps = 29/283 (10%)
Query: 155 ASSFSKTGAPRVLDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIE 214
++ F G +L ++ + LG G++G A+K L + +I
Sbjct: 5 SNRFGNNGVESILPNYKLGKTLGIGSFGKVKIAEHVVTGHKVAIKILNRRKI-------- 56
Query: 215 KDANTTVEKRIERTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKE 274
N +E+++ R E IL HP+I++ + +Y+V++Y+ GELF ++ E
Sbjct: 57 --KNMEMEEKVRR---EIKILRLFMHPHIIRQYEVIETTSDIYVVMEYVKSGELFDYIVE 111
Query: 275 QGTLDEGTVAFYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFD 334
+G L E + ++ +++ H +V+RDLKPEN LL+ R ++ + DFGLS +V
Sbjct: 112 KGRLQEDEARNFFQQIISGVEYCHRNMVVHRDLKPENLLLDSRCNIKIADFGLS--NVMR 169
Query: 335 DAATPEEGENVNQLYSIIGTPEYCAPEILAGEPYT-QNCDWYSLGCLVYDMLIGKPPFTG 393
D + L + G+P Y APE+++G+ Y D +S G ++Y +L G PF
Sbjct: 170 DG---------HFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYALLCGTLPFDD 220
Query: 394 VNHKIILNKIKQEKTGA-RIPSYLSDGFKDYLGALLRKDPTKR 435
N I N K+ K G +PS+LS +D + +L DP KR
Sbjct: 221 EN---IPNLFKKIKGGIYTLPSHLSSEARDLIPRMLIVDPVKR 260
>At3g17510 [T] KOG0583 Serine/threonine protein kinase
Length = 446
Score = 120 bits (300), Expect = 7e-27
Identities = 86/264 (32%), Positives = 129/264 (48%), Gaps = 26/264 (9%)
Query: 174 RCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVE-KRIERTFAER 232
R LGEG +G +A+K + K+ I D N +++ KR RT
Sbjct: 24 RTLGEGNFGKVKFAKDTVSGHSFAVKIIDKSRIA--------DLNFSLQIKREIRT---- 71
Query: 233 TILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAAELSC 292
L L+HP+IV+L K+ +V++ + GGELF + G L E +L
Sbjct: 72 --LKMLKHPHIVRLHEVLASKTKINMVMELVTGGELFDRIVSNGKLTETDGRKMFQQLID 129
Query: 293 ALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVNQLYSII 352
+ + HSKG+ +RDLK EN LL+ +GH+ +TDFGLS A P+ + L++
Sbjct: 130 GISYCHSKGVFHRDLKLENVLLDAKGHIKITDFGLS--------ALPQHFRDDGLLHTTC 181
Query: 353 GTPEYCAPEILAGEPYT-QNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQEKTGAR 411
G+P Y APE+LA Y D +S G ++Y +L G PF N ++ KI K
Sbjct: 182 GSPNYVAPEVLANRGYDGAASDIWSCGVILYVILTGCLPFDDRNLAVLYQKIC--KGDPP 239
Query: 412 IPSYLSDGFKDYLGALLRKDPTKR 435
IP +LS G + + +L +P R
Sbjct: 240 IPRWLSPGARTMIKRMLDPNPVTR 263
>At1g53570 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 608
Score = 120 bits (300), Expect = 7e-27
Identities = 75/261 (28%), Positives = 127/261 (47%), Gaps = 23/261 (8%)
Query: 176 LGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIERTFAERTIL 235
LG G +G A+K++K +IS+D K+ + + I +L
Sbjct: 220 LGSGTFGQVYLGFNSEKGKMCAIKEVK----VISDDQTSKECLKQLNQEIN-------LL 268
Query: 236 SQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAAELSCALK 295
+QL HPNIV+ + S L + L+Y+ GG + LK+ G+ E + Y ++ L
Sbjct: 269 NQLCHPNIVQYYGSELSEETLSVYLEYVSGGSIHKLLKDYGSFTEPVIQNYTRQILAGLA 328
Query: 296 FLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVNQLYSIIGTP 355
+LH + V+RD+K N L++ G + L DFG++K + + S G+P
Sbjct: 329 YLHGRNTVHRDIKGANILVDPNGEIKLADFGMAKHVT-----------AFSTMLSFKGSP 377
Query: 356 EYCAPEILAGE-PYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQEKTGARIPS 414
+ APE++ + YT D +SLGC + +M KPP++ + KI K IP
Sbjct: 378 YWMAPEVVMSQNGYTHAVDIWSLGCTILEMATSKPPWSQFEGVAAIFKIGNSKDTPEIPD 437
Query: 415 YLSDGFKDYLGALLRKDPTKR 435
+LS+ K+++ L+++PT R
Sbjct: 438 HLSNDAKNFIRLCLQRNPTVR 458
>At4g09570 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 501
Score = 119 bits (299), Expect = 9e-27
Identities = 89/300 (29%), Positives = 141/300 (46%), Gaps = 41/300 (13%)
Query: 164 PRVLDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEK 223
PR+ D ++ + LG+G +G YA K + K +++ ED
Sbjct: 19 PRLRDHYLLGKKLGQGQFGTTYLCTEKSSSANYACKSIPKRKLVCRED------------ 66
Query: 224 RIERTFAERTILSQL-EHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGT 282
E + E I+ L EHPN+V++ ++ D+ +++V++ GGELF + +G E
Sbjct: 67 -YEDVWREIQIMHHLSEHPNVVRIKGTYEDSVFVHIVMEVCEGGELFDRIVSKGCFSERE 125
Query: 283 VAFYAAELSCALKFLHSKGIVYRDLKPENCLL---NERGHLVLTDFGLSKKSVFDDAATP 339
A + ++ HS G+++RDLKPEN L ++ L TDFGL SVF
Sbjct: 126 AAKLIKTILGVVEACHSLGVMHRDLKPENFLFDSPSDDAKLKATDFGL---SVFYKPG-- 180
Query: 340 EEGENVNQLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKII 399
LY ++G+P Y APE+L + Y D +S G ++Y +L G PPF I
Sbjct: 181 ------QYLYDVVGSPYYVAPEVLK-KCYGPEIDVWSAGVILYILLSGVPPFWAETESGI 233
Query: 400 LNKIKQEKTGARIPSY--LSDGFKDYLGALLRKDPTKR----------WDVDKYWAQDGP 447
+I Q K + + +S+G KD + +L + P KR W VD++ A D P
Sbjct: 234 FRQILQGKIDFKSDPWPTISEGAKDLIYKMLDRSPKKRISAHEALCHPWIVDEHAAPDKP 293
>Hs7657214 [T] KOG0583 Serine/threonine protein kinase
Length = 714
Score = 119 bits (298), Expect = 1e-26
Identities = 88/277 (31%), Positives = 133/277 (47%), Gaps = 21/277 (7%)
Query: 165 RVLDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKR 224
RV + + R LGEG++ A+K +I + +KD T V K
Sbjct: 57 RVGNYLIGSRKLGEGSFAKVREGLHVLTGEKVAIK-------VIDKKRAKKD--TYVTKN 107
Query: 225 IERTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVA 284
+ R E I + HPNI +L + YLV++ PGG L + + E+ L+E
Sbjct: 108 LRR---EGQIQQMIRHPNITQLLDILETENSYYLVMELCPGGNLMHKIYEKKRLEESEAR 164
Query: 285 FYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGEN 344
Y +L A++ LH G+V+RDLK EN LL+E ++ L DFGLS + + P +
Sbjct: 165 RYIRQLISAVEHLHRAGVVHRDLKIENLLLDEDNNIKLIDFGLSNCAGILGYSDPFSTQ- 223
Query: 345 VNQLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKI-ILNKI 403
G+P Y APE+LA + Y D +S+G +Y ML G PFT + L +
Sbjct: 224 -------CGSPAYAAPELLARKKYGPKIDVWSIGVNMYAMLTGTLPFTVEPFSLRALYQK 276
Query: 404 KQEKTGARIPSYLSDGFKDYLGALLRKDPTKRWDVDK 440
+K +P+ LS G +L +LL DP KR ++ +
Sbjct: 277 MVDKEMNPLPTQLSTGAISFLRSLLEPDPVKRPNIQQ 313
>At2g26980 [T] KOG0583 Serine/threonine protein kinase
Length = 441
Score = 119 bits (298), Expect = 1e-26
Identities = 79/264 (29%), Positives = 127/264 (47%), Gaps = 26/264 (9%)
Query: 174 RCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIERTFAERT 233
R +GEG + A+K L K ++L K E+ E
Sbjct: 18 RTIGEGTFAKVKFARNSETGEPVALKILDKEKVL-------------KHKMAEQIRREIA 64
Query: 234 ILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAAELSCA 293
+ ++HPN+V+L+ K++++L+Y+ GGELF + G + E Y +L A
Sbjct: 65 TMKLIKHPNVVQLYEVMASKTKIFIILEYVTGGELFDKIVNDGRMKEDEARRYFQQLIHA 124
Query: 294 LKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVNQLYSIIG 353
+ + HS+G+ +RDLKPEN LL+ G+L ++DFGLS A ++ + L++ G
Sbjct: 125 VDYCHSRGVYHRDLKPENLLLDSYGNLKISDFGLS--------ALSQQVRDDGLLHTSCG 176
Query: 354 TPEYCAPEILAGEPYT-QNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQEKTGA-R 411
TP Y APE+L Y D +S G ++Y +L G PF N ++N K+ +G
Sbjct: 177 TPNYVAPEVLNDRGYDGATADMWSCGVVLYVLLAGYLPFDDSN---LMNLYKKISSGEFN 233
Query: 412 IPSYLSDGFKDYLGALLRKDPTKR 435
P +LS G + +L +P R
Sbjct: 234 CPPWLSLGAMKLITRILDPNPMTR 257
>YMR001c [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 705
Score = 119 bits (297), Expect = 2e-26
Identities = 79/237 (33%), Positives = 121/237 (50%), Gaps = 19/237 (8%)
Query: 208 ISEDSIEKDANTTV-------EKRIERTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVL 260
I +DS E A TV EK ++ +E I + HPNIV+ F D+ +Y++L
Sbjct: 99 IKDDSGEIFAAKTVAKASIKSEKTRKKLLSEIQIHKSMSHPNIVQFIDCFEDDSNVYILL 158
Query: 261 QYIPGGELFYHLKEQGTLDEGTVAFYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHL 320
+ P G L LK + L E V F+ ++ A+K++HS+ +++RDLK N + +L
Sbjct: 159 EICPNGSLMELLKRRKVLTEPEVRFFTTQICGAIKYMHSRRVIHRDLKLGNIFFDSNYNL 218
Query: 321 VLTDFGLSKKSVFDDAATPEEGENVNQLYSIIGTPEYCAPEILAGE--PYTQNCDWYSLG 378
+ DFGL+ A E E + Y+I GTP Y APE+L G+ ++ D +SLG
Sbjct: 219 KIGDFGLA-------AVLANESE---RKYTICGTPNYIAPEVLMGKHSGHSFEVDIWSLG 268
Query: 379 CLVYDMLIGKPPFTGVNHKIILNKIKQEKTGARIPSYLSDGFKDYLGALLRKDPTKR 435
++Y +LIGKPPF + I +IK +SD K + +L DP +R
Sbjct: 269 VMLYALLIGKPPFQARDVNTIYERIKCRDFSFPRDKPISDEGKILIRDILSLDPIER 325
>YLR096w [T] KOG0583 Serine/threonine protein kinase
Length = 1147
Score = 119 bits (297), Expect = 2e-26
Identities = 76/234 (32%), Positives = 128/234 (54%), Gaps = 19/234 (8%)
Query: 203 KAEILISEDSIEKDANTTVEKRIERTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQY 262
++EIL + +EK+ R +RT E ++ L HP+I +LF ++ Y++ +Y
Sbjct: 150 ESEILERQKRLEKEI-----ARDKRTVREASLGQILYHPHICRLFEMCTMSNHFYMLFEY 204
Query: 263 IPGGELFYHLKEQGTLDEGTVAFYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVL 322
+ GG+L ++ + G+L E +A ++ AL++LH+ IV+RDLK EN +++ G + +
Sbjct: 205 VSGGQLLDYIIQHGSLKEHHARKFARGIASALQYLHANNIVHRDLKIENIMISSSGEIKI 264
Query: 323 TDFGLSKKSVFDDAATPEEGENVNQLYSIIGTPEYCAPEILAGEPYT-QNCDWYSLGCLV 381
DFGLS ++FD QL++ G+ + APE+L +PYT D +S G ++
Sbjct: 265 IDFGLS--NIFDYR---------KQLHTFCGSLYFAAPELLKAQPYTGPEVDIWSFGIVL 313
Query: 382 YDMLIGKPPFTGVNHKIILNKIKQEKTGARIPSYLSDGFKDYLGALLRKDPTKR 435
Y ++ GK PF N I+ KIK+ K PS+LS L ++ DP +R
Sbjct: 314 YVLVCGKVPFDDENSSILHEKIKKGKVD--YPSHLSIEVISLLTRMIVVDPLRR 365
>Hs7662170 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 661
Score = 118 bits (296), Expect = 2e-26
Identities = 79/272 (29%), Positives = 135/272 (49%), Gaps = 33/272 (12%)
Query: 176 LGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIERTFAERTIL 235
LG+G YG A+K ++K +I +D + + + IE I+
Sbjct: 61 LGKGTYGKVKRATERFSGRVVAIKSIRKDKIKDEQDMVH------IRREIE-------IM 107
Query: 236 SQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAAELSCALK 295
S L HP+I+ ++ F + K+ ++++Y GEL+ ++ E+ L E + ++ A+
Sbjct: 108 SSLNHPHIISIYEVFENKDKIVIIMEYASKGELYDYISERRRLSERETRHFFRQIVSAVH 167
Query: 296 FLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVNQLYSIIGTP 355
+ H G+V+RDLK EN LL++ ++ + DFGLS D L + G+P
Sbjct: 168 YCHKNGVVHRDLKLENILLDDNCNIKIADFGLSNLYQKD-----------KFLQTFCGSP 216
Query: 356 EYCAPEILAGEPYT-QNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQEKTGA-RIP 413
Y +PEI+ G PY D ++LG L+Y ++ G PF G +HK N I+Q +G R P
Sbjct: 217 LYASPEIVNGRPYRGPEVDSWALGVLLYTLVYGTMPFDGFDHK---NLIRQISSGEYREP 273
Query: 414 SYLSDGFKDYLGALLRKDPTKR---WDVDKYW 442
+ SD + + +L +P +R D+ +W
Sbjct: 274 TQPSDA-RGLIRWMLMVNPDRRATIEDIANHW 304
>CE15235 [R] KOG0589 Serine/threonine protein kinase
Length = 357
Score = 118 bits (296), Expect = 2e-26
Identities = 86/284 (30%), Positives = 142/284 (49%), Gaps = 34/284 (11%)
Query: 167 LDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIE 226
+D++ +R +G GA+G A Q +++ + EK+ N+
Sbjct: 1 MDNYEKVRVVGRGAFGVCWLCRGKND----ASHQKVIIKLINTHGMTEKEENSIQ----- 51
Query: 227 RTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLD------- 279
+E +L +++HP I+ SF +++L +V+QY GG L + +Q +
Sbjct: 52 ---SEVNLLKKVQHPLIIGYIDSFIMDNQLGIVMQYAEGGTLERLINDQRAIKDSNMREY 108
Query: 280 --EGTVAFYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLV-LTDFGLSKKSVFDDA 336
E TV Y ++ AL +H K IV+RDLKP+N L+N R ++ L+DFG+SK+ A
Sbjct: 109 FPEKTVLDYFTQILIALNHMHQKNIVHRDLKPQNILMNRRKTVLKLSDFGISKELGTKSA 168
Query: 337 ATPEEGENVNQLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNH 396
A+ ++IGTP Y +PEI PY Q D +SLGC++Y++L + F G N
Sbjct: 169 AS-----------TVIGTPNYLSPEICESRPYNQKSDMWSLGCVLYELLQLERAFDGENL 217
Query: 397 KIILNKIKQEKTGARIPSYLSDGFKDYLGALLRKDPTKRWDVDK 440
I+ KI + K + ++S+ K + LL+ KR DV +
Sbjct: 218 PAIVMKITRSKQNP-LGDHVSNDVKMLVENLLKTHTDKRPDVSQ 260
>At4g18700 [T] KOG0583 Serine/threonine protein kinase
Length = 489
Score = 118 bits (296), Expect = 2e-26
Identities = 74/207 (35%), Positives = 112/207 (53%), Gaps = 12/207 (5%)
Query: 231 ERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAAEL 290
E +IL ++ HPNIV+LF K+Y V++Y+ GGELF + + G L E Y +L
Sbjct: 74 EISILRRVRHPNIVQLFEVMATKAKIYFVMEYVRGGELFNKVAK-GRLKEEVARKYFQQL 132
Query: 291 SCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVNQLYS 350
A+ F H++G+ +RDLKPEN LL+E G+L ++DFGLS A ++ ++
Sbjct: 133 ISAVTFCHARGVYHRDLKPENLLLDENGNLKVSDFGLS--------AVSDQIRQDGLFHT 184
Query: 351 IIGTPEYCAPEILAGEPY-TQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQEKTG 409
GTP Y APE+LA + Y D +S G +++ ++ G PF N + KI + +
Sbjct: 185 FCGTPAYVAPEVLARKGYDAAKVDIWSCGVILFVLMAGYLPFHDRNVMAMYKKIYRGE-- 242
Query: 410 ARIPSYLSDGFKDYLGALLRKDPTKRW 436
R P + S L LL +P KR+
Sbjct: 243 FRCPRWFSTELTRLLSKLLETNPEKRF 269
>Hs4505599 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 525
Score = 118 bits (295), Expect = 3e-26
Identities = 96/387 (24%), Positives = 166/387 (42%), Gaps = 42/387 (10%)
Query: 50 PLHKNQFRMDLSALPPNTYEEEALISDTEEQAEMMSGFLVPPDSGESKQSQTKEPARRRS 109
P K+ AL E A++++ E+ E + ++ P +K
Sbjct: 144 PPEKDGLPSGTPALNAKGTEAPAVVTEEEDDDEETAPPVIAPRPDHTK------------ 191
Query: 110 SLYNKFVVNPAQHTIRLSLNAQGDSDKETRDVLSVSSVEETRQLRASSFSKTGAPRVLDD 169
S+Y + V++P + S + G + + +E + + G P+
Sbjct: 192 SIYTRSVIDPVPAPVGDS-HVDGAAKSLDKQKKKPKMTDEEIMEKLRTIVSIGDPK--KK 248
Query: 170 FVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIERTF 229
+ +G+GA G A+KQ+ N + + E
Sbjct: 249 YTRYEKIGQGASGTVFTATDVALGQEVAIKQI----------------NLQKQPKKELII 292
Query: 230 AERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAAE 289
E ++ +L++PNIV S+ +L++V++Y+ GG L + E +DE +A E
Sbjct: 293 NEILVMKELKNPNIVNFLDSYLVGDELFVVMEYLAGGSLTDVVTETACMDEAQIAAVCRE 352
Query: 290 LSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVNQLY 349
AL+FLH+ +++RD+K +N LL G + LTDFG F TPE+ +
Sbjct: 353 CLQALEFLHANQVIHRDIKSDNVLLGMEGSVKLTDFG------FCAQITPEQSKR----S 402
Query: 350 SIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQEKT- 408
+++GTP + APE++ + Y D +SLG + +M+ G+PP+ N L I T
Sbjct: 403 TMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTP 462
Query: 409 GARIPSYLSDGFKDYLGALLRKDPTKR 435
+ P LS F+D+L L D KR
Sbjct: 463 ELQNPEKLSPIFRDFLNRCLEMDVEKR 489
>At5g01810 [T] KOG0583 Serine/threonine protein kinase
Length = 421
Score = 117 bits (294), Expect = 3e-26
Identities = 83/266 (31%), Positives = 128/266 (47%), Gaps = 25/266 (9%)
Query: 176 LGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIERTFAERTIL 235
LG+G + A+K + K IL + ++I+R E + +
Sbjct: 18 LGQGTFAKVYHARHLKTGDSVAIKVIDKERIL----------KVGMTEQIKR---EISAM 64
Query: 236 SQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAAELSCALK 295
L HPNIV+L K+Y V++++ GGELF + G L E Y +L A+
Sbjct: 65 RLLRHPNIVELHEVMATKSKIYFVMEHVKGGELFNKVST-GKLREDVARKYFQQLVRAVD 123
Query: 296 FLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVNQLYSIIGTP 355
F HS+G+ +RDLKPEN LL+E G+L ++DFGLS A + L++ GTP
Sbjct: 124 FCHSRGVCHRDLKPENLLLDEHGNLKISDFGLS--------ALSDSRRQDGLLHTTCGTP 175
Query: 356 EYCAPEILAGEPYTQ-NCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQEKTGARIPS 414
Y APE+++ Y D +S G +++ +L G PF N + KI K + P+
Sbjct: 176 AYVAPEVISRNGYDGFKADVWSCGVILFVLLAGYLPFRDSNLMELYKKI--GKAEVKFPN 233
Query: 415 YLSDGFKDYLGALLRKDPTKRWDVDK 440
+L+ G K L +L +P R +K
Sbjct: 234 WLAPGAKRLLKRILDPNPNTRVSTEK 259
>At1g30270 [T] KOG0583 Serine/threonine protein kinase
Length = 480
Score = 117 bits (294), Expect = 3e-26
Identities = 79/264 (29%), Positives = 128/264 (47%), Gaps = 28/264 (10%)
Query: 174 RCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIERTFAERT 233
R LGEG + A+K + K ++L + K I + E +
Sbjct: 35 RTLGEGTFAKVKFARNVENGDNVAIKVIDKEKVLKN-------------KMIAQIKREIS 81
Query: 234 ILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAAELSCA 293
+ ++HPN++++F K+Y VL+++ GGELF + G L E Y +L A
Sbjct: 82 TMKLIKHPNVIRMFEVMASKTKIYFVLEFVTGGELFDKISSNGRLKEDEARKYFQQLINA 141
Query: 294 LKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVNQLYSIIG 353
+ + HS+G+ +RDLKPEN LL+ G L ++DFGLS A P++ + + L++ G
Sbjct: 142 VDYCHSRGVYHRDLKPENLLLDANGALKVSDFGLS--------ALPQQEDGL--LHTTCG 191
Query: 354 TPEYCAPEILAGEPYT-QNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKI-KQEKTGAR 411
TP Y APE++ + Y D +S G +++ ++ G PF N + KI K E T
Sbjct: 192 TPNYVAPEVINNKGYDGAKADLWSCGVILFVLMAGYLPFEDSNLTSLYKKIFKAEFT--- 248
Query: 412 IPSYLSDGFKDYLGALLRKDPTKR 435
P + S K + +L +P R
Sbjct: 249 CPPWFSASAKKLIKRILDPNPATR 272
>Hs13899225 [R] KOG0586 Serine/threonine protein kinase
Length = 688
Score = 117 bits (293), Expect = 5e-26
Identities = 70/217 (32%), Positives = 111/217 (50%), Gaps = 14/217 (6%)
Query: 225 IERTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVA 284
+++ F E I+ L HPNIVKLF LYLV++Y GE+F +L G + E
Sbjct: 100 LQKLFREVRIMKGLNHPNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEAR 159
Query: 285 FYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGEN 344
++ A+ + H K IV+RDLK EN LL+ ++ + DFG S +
Sbjct: 160 AKFRQIVSAVHYCHQKNIVHRDLKAENLLLDAEANIKIADFGFSNEFTLG---------- 209
Query: 345 VNQLYSIIGTPEYCAPEILAGEPYT-QNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKI 403
++L + G+P Y APE+ G+ Y D +SLG ++Y ++ G PF G N K + ++
Sbjct: 210 -SKLDTFCGSPPYAAPELFQGKKYDGPEVDIWSLGVILYTLVSGSLPFDGHNLKELRERV 268
Query: 404 KQEKTGARIPSYLSDGFKDYLGALLRKDPTKRWDVDK 440
+ K R+P Y+S + L L +P KR +++
Sbjct: 269 LRGK--YRVPFYMSTDCESILRRFLVLNPAKRCTLEQ 303
>CE05780 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 336
Score = 117 bits (293), Expect = 5e-26
Identities = 64/207 (30%), Positives = 111/207 (52%), Gaps = 15/207 (7%)
Query: 231 ERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAAEL 290
E +LS ++H +I+ + +F ++ ++V ++ G+L+ +++ G ++E A ++
Sbjct: 120 EVEMLSLIQHDHIISIIDAFSTENQYFIVFEHAQYGDLYETIRKNGRIEEPDAAIITLQV 179
Query: 291 SCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVNQLYS 350
+ AL +LH + +V+RD+KPEN LL ++ + L DFGL+ + LY
Sbjct: 180 ASALNYLHERNVVHRDVKPENLLLVDKFSVKLCDFGLA-------------CHILGPLYR 226
Query: 351 IIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQEKTGA 410
I GTP YCAPE+L Y+ CD +SLG ++Y ML+G PF + + I Q K
Sbjct: 227 ICGTPTYCAPEVLRETGYSTRCDIWSLGVVLYVMLVGYAPFRAPDQTRLFKLIMQAKPNL 286
Query: 411 RIPSY--LSDGFKDYLGALLRKDPTKR 435
+P + +S KD + L+ K +R
Sbjct: 287 DMPEWKGISLKAKDLVSRLMNKTEERR 313
>At1g48260 [T] KOG0583 Serine/threonine protein kinase
Length = 432
Score = 117 bits (293), Expect = 5e-26
Identities = 87/273 (31%), Positives = 129/273 (46%), Gaps = 24/273 (8%)
Query: 174 RCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIERTFAERT 233
R LGEG +A+K ++K+ I V +I+R E
Sbjct: 15 RTLGEGNSAKVKFAIDTLTGESFAIKIIEKSCI----------TRLNVSFQIKR---EIR 61
Query: 234 ILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAAELSCA 293
L L+HPNIV+L K+Y+VL+ + GG+LF + +G L E +L
Sbjct: 62 TLKVLKHPNIVRLHEVLASKTKIYMVLECVTGGDLFDRIVSKGKLSETQGRKMFQQLIDG 121
Query: 294 LKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVNQLYSIIG 353
+ + H+KG+ +RDLK EN LL+ +GH+ +TDFGLS A + L++ G
Sbjct: 122 VSYCHNKGVFHRDLKLENVLLDAKGHIKITDFGLS--------ALSQHYREDGLLHTTCG 173
Query: 354 TPEYCAPEILAGEPYT-QNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQEKTGARI 412
+P Y APE+LA E Y D +S G ++Y +L G PF N +I KI K I
Sbjct: 174 SPNYVAPEVLANEGYDGAASDIWSCGVILYVILTGCLPFDDANLAVICRKI--FKGDPPI 231
Query: 413 PSYLSDGFKDYLGALLRKDPTKRWDVDKYWAQD 445
P ++S G K + +L +P R + A D
Sbjct: 232 PRWISLGAKTMIKRMLDPNPVTRVTIAGIKAHD 264
>7304311 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 405
Score = 117 bits (293), Expect = 5e-26
Identities = 69/205 (33%), Positives = 115/205 (55%), Gaps = 19/205 (9%)
Query: 196 YAMKQLKKAEILISEDSIEKDANTTVEKRIERTFAERTILS--QLEHPNIVKLFYSFHDN 253
+A+K + K + E+S+E + V +R + L+ +L HPNIV+L ++ D
Sbjct: 58 FAVKIIDKKALKGKEESLENEIR--VLRRFSANHFDGKCLNGTRLTHPNIVQLLETYEDK 115
Query: 254 HKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAAELSCALKFLHSKGIVYRDLKPENCL 313
K+YLV++ + GGELF + E+G+ E + ++ A+ ++H +G+V+RDLKPEN L
Sbjct: 116 SKVYLVMELVTGGELFDRIVEKGSYTEKDASHLIRQILEAVDYMHEQGVVHRDLKPENLL 175
Query: 314 L---NERGHLVLTDFGLSKKSVFDDAATPEEGENVNQLYSIIGTPEYCAPEILAGEPYTQ 370
++ ++++DFGLSK E+ + + GTP Y APE+LA +PY +
Sbjct: 176 YYSPDDDSKIMISDFGLSKM------------EDSGIMATACGTPGYVAPEVLAQKPYGK 223
Query: 371 NCDWYSLGCLVYDMLIGKPPFTGVN 395
D +S+G + Y +L G PPF N
Sbjct: 224 AVDVWSIGVISYILLCGYPPFYDEN 248
>7293512 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 483
Score = 117 bits (293), Expect = 5e-26
Identities = 75/195 (38%), Positives = 106/195 (53%), Gaps = 26/195 (13%)
Query: 196 YAMKQLKKAEILISEDSIEKDANTTVEKRIERTFAERTILSQLEHPNIVKLFYSFHDNHK 255
YA+K LKK++ LI ++S+ + + E I++ HP IVK + + H
Sbjct: 186 YALKVLKKSK-LIEDNSVRQIKD---EADIQKVCGH--------HPFIVKQIDLWQNRHN 233
Query: 256 LYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAAELSCALKFLHSKGIVYRDLKPENCLLN 315
L+++ +Y+P GELF + V Y E++ AL FLH+ GI+YRD KPEN LL
Sbjct: 234 LHILSEYVPNGELFSKITH---FSIDLVRLYIGEIALALDFLHNAGIIYRDAKPENILLT 290
Query: 316 ERGHLVLTDFGLSKKSVFDDAATPEEGENVNQLYSIIGTPEYCAPEILAGEPYTQNCDWY 375
E+ H+ LTDFGLSK + G N ++ GT +Y APEIL GEPY DW+
Sbjct: 291 EQFHIKLTDFGLSK--------WLKLGANTR---TMCGTFKYMAPEILCGEPYGHAVDWW 339
Query: 376 SLGCLVYDMLIGKPP 390
+LG + ML K P
Sbjct: 340 ALGVIACQMLTQKSP 354
>7290249 [R] KOG0586 Serine/threonine protein kinase
Length = 1398
Score = 117 bits (293), Expect = 5e-26
Identities = 71/247 (28%), Positives = 135/247 (53%), Gaps = 15/247 (6%)
Query: 196 YAMKQLKKAEILISEDSIEK-DANTTVEKRIERTFAERTILSQLEHPNIVKLFYSFHDNH 254
+A+ +L + I +E +I+ D + + +++ + E I+ +L+HP+I+KL+ +
Sbjct: 152 FAVVKLARHRITKNEVAIKIIDKSQLDQTNLQKVYREVEIMKRLKHPHIIKLYQVMETKN 211
Query: 255 KLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAAELSCALKFLHSKGIVYRDLKPENCLL 314
+Y+V +Y GE+F ++ + G + E F ++ A+++ H KGIV+RDLK EN LL
Sbjct: 212 MIYIVSEYASQGEIFDYIAKYGRMSESAARFKFWQIISAVEYCHKKGIVHRDLKAENLLL 271
Query: 315 NERGHLVLTDFGLSKKSVFDDAATPEEGENVNQLYSIIGTPEYCAPEILAGEPYT-QNCD 373
+ ++ + DFG F + P E L + G+P Y APE+ G+ YT D
Sbjct: 272 DLNMNIKIADFG------FSNHFKPGE-----LLATWCGSPPYAAPEVFEGKQYTGPEID 320
Query: 374 WYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQEKTGARIPSYLSDGFKDYLGALLRKDPT 433
+SLG ++Y ++ G PF G + + +++ + RIP ++S + + +L +PT
Sbjct: 321 IWSLGVVLYVLVCGALPFDGSTLQSLRDRVLSGR--FRIPFFMSSECEHLIRRMLVLEPT 378
Query: 434 KRWDVDK 440
+R+ +D+
Sbjct: 379 RRYTIDQ 385
>CE26793_1 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 795
Score = 117 bits (293), Expect = 5e-26
Identities = 82/271 (30%), Positives = 129/271 (47%), Gaps = 31/271 (11%)
Query: 176 LGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIERTFAERTIL 235
LG G YG A+K +KK+ I D + RI R E I+
Sbjct: 81 LGSGTYGKVSLAYDHKFDREVAVKLIKKSAIESKADLV----------RIRR---EIRIM 127
Query: 236 SQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAAELSCALK 295
S L HPNI++++ F + K+ LV++Y GGEL+ ++ G+L E +++ A+
Sbjct: 128 SALNHPNIIQIYEVFENKDKIILVMEYSSGGELYDYVSRCGSLPEAEARRIFRQITSAVL 187
Query: 296 FLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVNQLYSIIGTP 355
+ H + +RDLK EN LL++ + + DFGLS + F D N L + G+P
Sbjct: 188 YCHKHRVAHRDLKLENILLDQNNNAKIADFGLS--NYFADK---------NLLTTFCGSP 236
Query: 356 EYCAPEILAGEPYT-QNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQEKTGARIPS 414
Y +PEI+ G PY D +SLG L+Y ++ G PF G + ++Q K GA
Sbjct: 237 LYASPEIINGTPYKGPEVDCWSLGILLYTLVYGSMPFDGRDFN---RMVRQIKRGAYFEP 293
Query: 415 YLSDGFKDYLGALLRKDPTKR---WDVDKYW 442
+ +LR +P +R +D+ +W
Sbjct: 294 ETPSTASMLIRNMLRVNPERRATIFDIASHW 324
>SPCC162.10 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 338
Score = 116 bits (291), Expect = 8e-26
Identities = 64/178 (35%), Positives = 95/178 (52%), Gaps = 8/178 (4%)
Query: 222 EKRIERTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEG 281
E +I++ E +L L HP + K + F D K+YLV + GG+L YH+ ++ +E
Sbjct: 68 EHKIKKLRNEVLLLQSLNHPLLCKFYSEFEDETKIYLVTDLMLGGDLRYHISQR-KFNES 126
Query: 282 TVAFYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEE 341
+ + EL AL ++HSKG+++RD+KP+N LL+E+GH L DF ++ K T
Sbjct: 127 VIRIWMVELVSALIYIHSKGVLHRDVKPDNILLDEKGHCKLADFNVAAK-----VHTSSS 181
Query: 342 GENVNQLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKII 399
N +GTP Y APE L + DW+SLG Y+ L PF NH +I
Sbjct: 182 PSKSNMTVGRVGTPVYMAPETLIHAVSYKESDWWSLGITFYECLFQVRPFP--NHLLI 237
>Hs4505153 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 626
Score = 116 bits (291), Expect = 8e-26
Identities = 76/253 (30%), Positives = 122/253 (48%), Gaps = 20/253 (7%)
Query: 174 RCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIERTFAERT 233
+ LG+GA+G A KQ++ DS E K + E
Sbjct: 366 KLLGQGAFGRVYLCYDVDTGRELASKQVQ-----FDPDSPE------TSKEVSALECEIQ 414
Query: 234 ILSQLEHPNIVKLFYSFHDNHK--LYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAAELS 291
+L L+H IV+ + D + L + ++Y+PGG + LK G L E Y ++
Sbjct: 415 LLKNLQHERIVQYYGCLRDRAEKTLTIFMEYMPGGSVKDQLKAYGALTESVTRKYTRQIL 474
Query: 292 CALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVNQLYSI 351
+ +LHS IV+RD+K N L + G++ L DFG SK+ G + S+
Sbjct: 475 EGMSYLHSNMIVHRDIKGANILRDSAGNVKLGDFGASKR--LQTICMSGTG-----MRSV 527
Query: 352 IGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQEKTGAR 411
GTP + +PE+++GE Y + D +SLGC V +ML KPP+ + KI + T +
Sbjct: 528 TGTPYWMSPEVISGEGYGRKADVWSLGCTVVEMLTEKPPWAEYEAMAAIFKIATQPTNPQ 587
Query: 412 IPSYLSDGFKDYL 424
+PS++S+ +D+L
Sbjct: 588 LPSHISEHGRDFL 600
>CE25046 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 348
Score = 116 bits (291), Expect = 8e-26
Identities = 79/267 (29%), Positives = 132/267 (48%), Gaps = 33/267 (12%)
Query: 176 LGEGAYGXXXXXXXXXXXXX-YAMKQLKKAEILISEDSIEKDANTTVEKRIERTFAERTI 234
LG GA+ YA+K + K + E+S+E + +
Sbjct: 28 LGTGAFSKVFLAESKSDAGQMYAVKCIDKKALKGKEESLENEIK---------------V 72
Query: 235 LSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAAELSCAL 294
L +L H NIV+LF ++ + +YLV++ + GGELF + +G+ E + ++ A+
Sbjct: 73 LRKLRHNNIVQLFDTYDEKQFVYLVMELVTGGELFDRIVAKGSYTEQDASNLIRQVLEAV 132
Query: 295 KFLHSKGIVYRDLKPENCLL---NERGHLVLTDFGLSKKSVFDDAATPEEGENVNQLYSI 351
F+H G+V+RDLKPEN L +E ++++DFGLSK E+ + +
Sbjct: 133 GFMHDNGVVHRDLKPENLLYYNQDEDSKIMISDFGLSKT------------EDSGVMATA 180
Query: 352 IGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQEKTGAR 411
GTP Y APE+L +PY + D +S+G + Y +L G PPF + + +I + +
Sbjct: 181 CGTPGYVAPEVLQQKPYGKAVDVWSIGVIAYILLCGYPPFYDESDANLFAQIIKGEYEFD 240
Query: 412 IPSY--LSDGFKDYLGALLRKDPTKRW 436
P + +SD KD++ L+ DP R+
Sbjct: 241 APYWDQISDSAKDFITHLMCCDPEARF 267
>7302570 [R] KOG0586 Serine/threonine protein kinase
Length = 702
Score = 116 bits (291), Expect = 8e-26
Identities = 71/223 (31%), Positives = 115/223 (50%), Gaps = 24/223 (10%)
Query: 222 EKRIERTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEG 281
E+ + +TF E IL L HP+I +L+ +YLV +Y P GE+F HL G + E
Sbjct: 79 EEYLNKTFREIAILKSLRHPHITRLYEVMESQSMIYLVTEYAPNGEIFDHLVANGRMKEP 138
Query: 282 TVAFYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEE 341
A +L A+ + H +G+V+RDLK EN LL++ ++ L DFG S +++ AT
Sbjct: 139 EAARVFTQLVSAVHYCHRRGVVHRDLKAENVLLDKDMNIKLADFGFSNH--YEEGAT--- 193
Query: 342 GENVNQLYSIIGTPEYCAPEILAGEPYT-QNCDWYSLGCLVYDMLIGKPPFTG-----VN 395
L + G+P Y APE+ G Y D +SLG ++Y ++ G PF G +
Sbjct: 194 ------LKTWCGSPPYAAPEVFQGLEYDGPKSDIWSLGVVLYALVCGALPFDGKTILELK 247
Query: 396 HKIILNKIKQEKTGARIPSYLSDGFKDYLGALLRKDPTKRWDV 438
+++L K RIP ++S + + +L +P +R+ +
Sbjct: 248 SRVVLGKF-------RIPFFMSQECEQLIRNMLVVEPDRRYTI 283
>7302464 [R] KOG0586 Serine/threonine protein kinase
Length = 739
Score = 116 bits (291), Expect = 8e-26
Identities = 70/212 (33%), Positives = 113/212 (53%), Gaps = 14/212 (6%)
Query: 225 IERTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVA 284
+++ F E I+ L+HPNIVKLF LYL+++Y GGE+F +L G + E
Sbjct: 192 LQKLFREVRIMKMLDHPNIVKLFQVIETEKTLYLIMEYASGGEVFDYLVLHGRMKEKEAR 251
Query: 285 FYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGEN 344
++ A+++ H K I++RDLK EN LL+ ++ + DFG F + TP
Sbjct: 252 VKFRQIVSAVQYCHQKRIIHRDLKAENLLLDSELNIKIADFG------FSNEFTPG---- 301
Query: 345 VNQLYSIIGTPEYCAPEILAGEPYT-QNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKI 403
++L + G+P Y APE+ G+ Y D +SLG ++Y ++ G PF G + + ++
Sbjct: 302 -SKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERV 360
Query: 404 KQEKTGARIPSYLSDGFKDYLGALLRKDPTKR 435
+ K RIP Y+S ++ L L +P KR
Sbjct: 361 LRGK--YRIPFYMSTDCENLLRKFLVLNPAKR 390
>Hs4557511 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 454
Score = 116 bits (290), Expect = 1e-25
Identities = 83/269 (30%), Positives = 125/269 (45%), Gaps = 27/269 (10%)
Query: 176 LGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIERTFAERTIL 235
LG G + YA K +KK + S + ++ IER E IL
Sbjct: 19 LGSGQFAIVRKCRQKGTGKEYAAKFIKKRRLSSSRRGVSRE-------EIER---EVNIL 68
Query: 236 SQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAAELSCALK 295
++ HPNI+ L F + + L+L+ + GGELF L E+ +L E + ++ +
Sbjct: 69 REIRHPNIITLHDIFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGVH 128
Query: 296 FLHSKGIVYRDLKPENCLLNERG----HLVLTDFGLSKKSVFDDAATPEEGENVNQLYSI 351
+LHSK I + DLKPEN +L ++ + L DFG++ K E N+ +I
Sbjct: 129 YLHSKRIAHFDLKPENIMLLDKNVPNPRIKLIDFGIAHKI-----------EAGNEFKNI 177
Query: 352 IGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIK--QEKTG 409
GTPE+ APEI+ EP D +S+G + Y +L G PF G + L I
Sbjct: 178 FGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGETKQETLTNISAVNYDFD 237
Query: 410 ARIPSYLSDGFKDYLGALLRKDPTKRWDV 438
S S+ KD++ LL KDP +R +
Sbjct: 238 EEYFSNTSELAKDFIRRLLVKDPKRRMTI 266
>HsM7657627 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 970
Score = 115 bits (289), Expect = 1e-25
Identities = 79/270 (29%), Positives = 129/270 (47%), Gaps = 26/270 (9%)
Query: 167 LDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIE 226
++DF LG+G++ A+K + K + + ++
Sbjct: 9 IEDFKVGNLLGKGSFAGVYRAESIHTGLEVAIKMIDKKAMYKAG-------------MVQ 55
Query: 227 RTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQ-GTLDEGTVAF 285
R E I QL+HP+I++L+ F D++ +YLVL+ GE+ +LK + E
Sbjct: 56 RVKNEVKIHCQLKHPSILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARH 115
Query: 286 YAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENV 345
+ ++ + +LHS GI++RDL N LL ++ + DFGL+ + P E
Sbjct: 116 FMHQIITGMLYLHSHGILHRDLTLSNLLLTRNMNIKIADFGLATQ-----LKMPHEKH-- 168
Query: 346 NQLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQ 405
Y++ GTP Y +PEI + D +SLGC+ Y +LIG+PPF K LNK+
Sbjct: 169 ---YTLCGTPNYISPEIATRSAHGLESDVWSLGCMFYTLLIGRPPFDTDTVKNTLNKV-- 223
Query: 406 EKTGARIPSYLSDGFKDYLGALLRKDPTKR 435
+P++LS KD + LLR++P R
Sbjct: 224 VLADYEMPTFLSIEAKDLIHQLLRRNPADR 253
>Hs21361433 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 970
Score = 115 bits (289), Expect = 1e-25
Identities = 79/270 (29%), Positives = 129/270 (47%), Gaps = 26/270 (9%)
Query: 167 LDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIE 226
++DF LG+G++ A+K + K + + ++
Sbjct: 9 IEDFKVGNLLGKGSFAGVYRAESIHSGLEVAIKMIDKKAMYKAG-------------MVQ 55
Query: 227 RTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQ-GTLDEGTVAF 285
R E I QL+HP+I++L+ F D++ +YLVL+ GE+ +LK + E
Sbjct: 56 RVQNEVKIHCQLKHPSILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARH 115
Query: 286 YAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENV 345
+ ++ + +LHS GI++RDL N LL ++ + DFGL+ + P E
Sbjct: 116 FMHQIITGMLYLHSHGILHRDLTLSNLLLTRNMNIKIADFGLATQ-----LKMPHEKH-- 168
Query: 346 NQLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQ 405
Y++ GTP Y +PEI + D +SLGC+ Y +LIG+PPF K LNK+
Sbjct: 169 ---YTLCGTPNYISPEIATRSAHGLESDVWSLGCMFYTLLIGRPPFDTDTVKNTLNKV-- 223
Query: 406 EKTGARIPSYLSDGFKDYLGALLRKDPTKR 435
+P++LS KD + LLR++P R
Sbjct: 224 VLADYEMPTFLSIEAKDLIHQLLRRNPADR 253
>7297611 [T] KOG0614 cGMP-dependent protein kinase
Length = 1003
Score = 115 bits (289), Expect = 1e-25
Identities = 80/269 (29%), Positives = 133/269 (48%), Gaps = 25/269 (9%)
Query: 167 LDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIE 226
+ + I LG GA+G A+K +KK E+ + +D IE N EK +
Sbjct: 691 ISELKKIATLGCGAFGRVDLVAYNQQAL--ALKIIKKIEV-VKQDQIEHVYN---EKNV- 743
Query: 227 RTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFY 286
++ + P IV+L+ ++ ++ +Y +++ GG+++ + ++ DE T F
Sbjct: 744 -------MIKCRQSPFIVQLYRTYRNDKYVYFLMEACMGGDVWTVMSKRQYFDEKTAKFI 796
Query: 287 AAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVN 346
A + A +LHS +YRDLKPEN +L G+ L DFG +K + E N
Sbjct: 797 AGCVVEAFDYLHSHHFIYRDLKPENLMLGTDGYCKLVDFGFAK--------FVRQNEKTN 848
Query: 347 QLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQE 406
+ GTPEY APEI+ + + D+++LG LVY++L+GK PF GVN I +I
Sbjct: 849 ---TFAGTPEYVAPEIILDRGHDRAVDYWALGILVYELLVGKTPFRGVNQIKIYQQILSG 905
Query: 407 KTGARIPSYLSDGFKDYLGALLRKDPTKR 435
+PS + + + L ++ P +R
Sbjct: 906 IDVIHMPSRIPKSAQHLVRHLCKQLPAER 934
>Hs22042851 [T] KOG0986 G protein-coupled receptor kinase
Length = 266
Score = 115 bits (288), Expect = 2e-25
Identities = 68/175 (38%), Positives = 94/175 (52%), Gaps = 15/175 (8%)
Query: 265 GGELFYHLKEQGT--LDEGTVAFYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVL 322
GG+L +H+ G DE FYAAEL C L+ L + IVYRDLKPEN LL++RGH+ +
Sbjct: 3 GGDLKFHIYNLGNPGFDEQRAVFYAAELCCGLEDLQRERIVYRDLKPENILLDDRGHIRI 62
Query: 323 TDFGLSKKSVFDDAATPEEGENVNQLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVY 382
+D GL A EG+ V +GT Y APE++ E YT + DW+ LGCL+Y
Sbjct: 63 SDLGL--------ATEIPEGQRVR---GRVGTVGYMAPEVVNNEKYTFSPDWWGLGCLIY 111
Query: 383 DMLIGKPPFTGVNHKIILNKIKQ--EKTGARIPSYLSDGFKDYLGALLRKDPTKR 435
+M+ G PF K+ ++ Q + S+ K LL K+P+KR
Sbjct: 112 EMIQGHSPFKKYKEKVKWEEVDQRIKNDTEEYSEKFSEDAKSICRMLLTKNPSKR 166
>Hs14776113 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 424
Score = 115 bits (288), Expect = 2e-25
Identities = 83/294 (28%), Positives = 138/294 (46%), Gaps = 32/294 (10%)
Query: 148 EETRQLRASSFSKTGAPRVLDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEIL 207
E R+ R + + PRV + +G G++ YA+K ++
Sbjct: 76 EPPRRARVAKYRAKFDPRVTAKYDIKALIGRGSFSRVVRVEHRATRQPYAIKMIE----- 130
Query: 208 ISEDSIEKDANTTVEKRIERTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGE 267
T + E +E +L ++ H NI++L F ++Y+V++ GGE
Sbjct: 131 -----------TKYREGREVCESELRVLRRVRHANIIQLVEVFETQERVYMVMELATGGE 179
Query: 268 LFYHLKEQGTLDEGTVAFYAAELSCALKFLHSKGIVYRDLKPENCLLNERG---HLVLTD 324
LF + +G+ E + +++LH+ GI +RDLKPEN L G +++TD
Sbjct: 180 LFDRIIAKGSFTERDATRVLQMVLDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITD 239
Query: 325 FGLSKKSVFDDAATPEEGENVNQLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDM 384
FGL A+ ++G++ + + GTPEY APE+L +PYT + D ++LG + Y +
Sbjct: 240 FGL--------ASARKKGDDC-LMKTTCGTPEYIAPEVLVRKPYTNSVDMWALGVIAYIL 290
Query: 385 LIGKPPFTGVNHKIILNKI---KQEKTGARIPSYLSDGFKDYLGALLRKDPTKR 435
L G PF N + +I K +G PS +S+ KD++ LL DP R
Sbjct: 291 LSGTMPFEDDNRTRLYRQILRGKYSYSGEPWPS-VSNLAKDFIDRLLTVDPGAR 343
>HsM4505103 [R] KOG0586 Serine/threonine protein kinase
Length = 713
Score = 115 bits (287), Expect = 2e-25
Identities = 70/217 (32%), Positives = 113/217 (51%), Gaps = 14/217 (6%)
Query: 225 IERTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVA 284
+++ F E I+ L HPNIVKLF LYL+++Y GG++F +L G + E
Sbjct: 97 LQKLFREVRIMKILNHPNIVKLFEVIETQKTLYLIMEYASGGKVFDYLVAHGRMKEKEAR 156
Query: 285 FYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGEN 344
++ A+++ H K IV+RDLK EN LL+ ++ + DFG S +
Sbjct: 157 SKFRQIVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEFTVG---------- 206
Query: 345 VNQLYSIIGTPEYCAPEILAGEPYT-QNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKI 403
+L + G+P Y APE+ G+ Y D +SLG ++Y ++ G PF G N K + ++
Sbjct: 207 -GKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERV 265
Query: 404 KQEKTGARIPSYLSDGFKDYLGALLRKDPTKRWDVDK 440
+ K RIP Y+S ++ L L +P KR +++
Sbjct: 266 LRGK--YRIPFYMSTDCENLLKRFLVLNPIKRGTLEQ 300
>At1g63700 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 883
Score = 115 bits (287), Expect = 2e-25
Identities = 77/263 (29%), Positives = 130/263 (49%), Gaps = 23/263 (8%)
Query: 174 RCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIERTFAERT 233
R LG G++G AMK++ L S+D +++ + + I +
Sbjct: 404 RLLGMGSFGHVYLGFNSESGEMCAMKEVT----LCSDDPKSRESAQQLGQEI-------S 452
Query: 234 ILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAAELSCA 293
+LS+L H NIV+ + S + KLY+ L+Y+ GG ++ L+E G E + Y ++
Sbjct: 453 VLSRLRHQNIVQYYGSETVDDKLYIYLEYVSGGSIYKLLQEYGQFGENAIRNYTQQILSG 512
Query: 294 LKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVNQLYSIIG 353
L +LH+K V+RD+K N L++ G + + DFG++K T + G S G
Sbjct: 513 LAYLHAKNTVHRDIKGANILVDPHGRVKVADFGMAKH------ITAQSGP-----LSFKG 561
Query: 354 TPEYCAPEILAGEPYTQ-NCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQEKTGARI 412
+P + APE++ + D +SLGC V +M KPP++ + KI K I
Sbjct: 562 SPYWMAPEVIKNSNGSNLAVDIWSLGCTVLEMATTKPPWSQYEGVPAMFKIGNSKELPDI 621
Query: 413 PSYLSDGFKDYLGALLRKDPTKR 435
P +LS+ KD++ L+++P R
Sbjct: 622 PDHLSEEGKDFVRKCLQRNPANR 644
>At1g54960 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 585
Score = 115 bits (287), Expect = 2e-25
Identities = 74/261 (28%), Positives = 131/261 (49%), Gaps = 17/261 (6%)
Query: 176 LGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIERTFAERTIL 235
+G GA+G A+KQ +LI+ + K+ + I+ E +L
Sbjct: 74 IGRGAFGTVYMGMNLDSGELLAVKQ-----VLITSNCASKEKT---QAHIQELEEEVKLL 125
Query: 236 SQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAAELSCALK 295
L HPNIV+ + ++ L ++L+++PGG + L++ G E V Y +L L+
Sbjct: 126 KNLSHPNIVRYLGTVREDETLNILLEFVPGGSISSLLEKFGAFPESVVRTYTNQLLLGLE 185
Query: 296 FLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVNQLYSIIGTP 355
+LH+ I++RD+K N L++ +G + L DFG SK+ E ++ S+ GTP
Sbjct: 186 YLHNHAIMHRDIKGANILVDNQGCIKLADFGASKQVA--------ELATISGAKSMKGTP 237
Query: 356 EYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKI-ILNKIKQEKTGARIPS 414
+ APE++ ++ + D +S+GC V +M+ GK P++ +I + I K+ IP
Sbjct: 238 YWMAPEVILQTGHSFSADIWSVGCTVIEMVTGKAPWSQQYKEIAAIFHIGTTKSHPPIPD 297
Query: 415 YLSDGFKDYLGALLRKDPTKR 435
+S D+L L+++P R
Sbjct: 298 NISSDANDFLLKCLQQEPNLR 318
>At1g35670 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 495
Score = 115 bits (287), Expect = 2e-25
Identities = 87/300 (29%), Positives = 138/300 (46%), Gaps = 41/300 (13%)
Query: 164 PRVLDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEK 223
PR+ D ++ + LG+G +G YA K + K +++ ED
Sbjct: 20 PRLRDHYLLGKKLGQGQFGTTYLCTEKSTSANYACKSIPKRKLVCRED------------ 67
Query: 224 RIERTFAERTILSQL-EHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGT 282
E + E I+ L EHPN+V++ ++ D+ +++V++ GGELF + +G E
Sbjct: 68 -YEDVWREIQIMHHLSEHPNVVRIKGTYEDSVFVHIVMEVCEGGELFDRIVSKGHFSERE 126
Query: 283 VAFYAAELSCALKFLHSKGIVYRDLKPENCLLN---ERGHLVLTDFGLSKKSVFDDAATP 339
+ ++ HS G+++RDLKPEN L + + L TDFGL SVF
Sbjct: 127 AVKLIKTILGVVEACHSLGVMHRDLKPENFLFDSPKDDAKLKATDFGL---SVFYKPG-- 181
Query: 340 EEGENVNQLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGCLVYDMLIGKPPFTGVNHKII 399
LY ++G+P Y APE+L + Y D +S G ++Y +L G PPF I
Sbjct: 182 ------QYLYDVVGSPYYVAPEVLK-KCYGPEIDVWSAGVILYILLSGVPPFWAETESGI 234
Query: 400 LNKIKQEKTGARIPSY--LSDGFKDYLGALLRKDPTKR----------WDVDKYWAQDGP 447
+I Q K + + +S+ KD + +L + P KR W VD+ A D P
Sbjct: 235 FRQILQGKLDFKSDPWPTISEAAKDLIYKMLERSPKKRISAHEALCHPWIVDEQAAPDKP 294
>At1g01140 [T] KOG0583 Serine/threonine protein kinase
Length = 447
Score = 115 bits (287), Expect = 2e-25
Identities = 78/263 (29%), Positives = 127/263 (47%), Gaps = 24/263 (9%)
Query: 174 RCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIERTFAERT 233
R LGEG++ A+K L + ++ K +E+ E +
Sbjct: 23 RTLGEGSFAKVKYAKNTVTGDQAAIKILDREKVFR-------------HKMVEQLKREIS 69
Query: 234 ILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAAELSCA 293
+ ++HPN+V++ K+Y+VL+ + GGELF + +QG L E Y +L A
Sbjct: 70 TMKLIKHPNVVEIIEVMASKTKIYIVLELVNGGELFDKIAQQGRLKEDEARRYFQQLINA 129
Query: 294 LKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVNQLYSIIG 353
+ + HS+G+ +RDLKPEN +L+ G L ++DFGLS S E+G L++ G
Sbjct: 130 VDYCHSRGVYHRDLKPENLILDANGVLKVSDFGLSAFS----RQVREDG----LLHTACG 181
Query: 354 TPEYCAPEILAGEPYT-QNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQEKTGARI 412
TP Y APE+L+ + Y D +S G +++ ++ G PF N + +I K
Sbjct: 182 TPNYVAPEVLSDKGYDGAAADVWSCGVILFVLMAGYLPFDEPNLMTLYKRIC--KAEFSC 239
Query: 413 PSYLSDGFKDYLGALLRKDPTKR 435
P + S G K + +L +P R
Sbjct: 240 PPWFSQGAKRVIKRILEPNPITR 262
>YDR122w [T] KOG0583 Serine/threonine protein kinase
Length = 1064
Score = 114 bits (286), Expect = 3e-25
Identities = 90/356 (25%), Positives = 160/356 (44%), Gaps = 27/356 (7%)
Query: 94 GESKQSQTKEPARRRSSLYNKFVVNPAQHTIRLSLNAQGDSDKETRDVLSVSSVEETRQL 153
G+S Q Q ++ K+ N H K + ++ ++R
Sbjct: 44 GKSPQQQQQQNTPLMPPADIKYANNGNSHQAEQKERQVELEGKSRENAPKPNTTSQSRVS 103
Query: 154 RASSFSKTGAPRVLDDFVPIRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKA-------EI 206
+ K + L D+ + +G G+ G A+K + +A E
Sbjct: 104 SSQGMPKQFHRKSLGDWEFVETVGAGSMGKVKLAKHRYTNEVCAVKIVNRATKAFLHKEQ 163
Query: 207 LISEDSIEKDA---NTTVEKRI---ERTFAERTILSQLEHPNIVKLFYSFHDNHKLYLVL 260
++ E+D +EK I +RT E ++ L HP+I +LF ++ Y++
Sbjct: 164 MLPPPKNEQDVLERQKKLEKEISRDKRTIREASLGQILYHPHICRLFEMCTLSNHFYMLF 223
Query: 261 QYIPGGELFYHLKEQGTLDEGTVAFYAAELSCALKFLHSKGIVYRDLKPENCLLNERGHL 320
+Y+ GG+L ++ + G++ E +A ++ AL +LH+ IV+RDLK EN ++++ +
Sbjct: 224 EYVSGGQLLDYIIQHGSIREHQARKFARGIASALIYLHANNIVHRDLKIENIMISDSSEI 283
Query: 321 VLTDFGLSKKSVFDDAATPEEGENVNQLYSIIGTPEYCAPEILAGEPYT-QNCDWYSLGC 379
+ DFGLS +++D QL++ G+ + APE+L PYT D +S G
Sbjct: 284 KIIDFGLS--NIYDSR---------KQLHTFCGSLYFAAPELLKANPYTGPEVDVWSFGV 332
Query: 380 LVYDMLIGKPPFTGVNHKIILNKIKQEKTGARIPSYLSDGFKDYLGALLRKDPTKR 435
+++ ++ GK PF N ++ KIKQ K P +LS L +L DP +R
Sbjct: 333 VLFVLVCGKVPFDDENSSVLHEKIKQGK--VEYPQHLSIEVISLLSKMLVVDPKRR 386
>Hs13569922 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 628
Score = 114 bits (286), Expect = 3e-25
Identities = 85/275 (30%), Positives = 139/275 (49%), Gaps = 34/275 (12%)
Query: 173 IRCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIERTFAER 232
+ LG+G YG A+K ++K +I +D + + + IE
Sbjct: 56 LETLGKGTYGKVKKARESSGRLV-AIKSIRKDKIKDEQDLMH------IRREIE------ 102
Query: 233 TILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAAELSC 292
I+S L HP+I+ + F ++ K+ +V++Y G+L+ ++ E+ L E + ++
Sbjct: 103 -IMSSLNHPHIIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVS 161
Query: 293 ALKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVNQLYSII 352
A+ + H +V+RDLK EN LL+ G++ + DFGLS +G+ L +
Sbjct: 162 AVHYCHQNRVVHRDLKLENILLDANGNIKIADFGLSN--------LYHQGK---FLQTFC 210
Query: 353 GTPEYCAPEILAGEPYT-QNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQEKTGA- 410
G+P Y +PEI+ G+PYT D +SLG L+Y ++ G PF G +HKI+ +KQ GA
Sbjct: 211 GSPLYASPEIVNGKPYTGPEVDSWSLGVLLYILVHGTMPFDGHDHKIL---VKQISNGAY 267
Query: 411 RIPSYLSDGFKDYLGALLRKDPTKR---WDVDKYW 442
R P SD + LL +PT+R DV +W
Sbjct: 268 REPPKPSDAC-GLIRWLLMVNPTRRATLEDVASHW 301
>At4g30960 [T] KOG0583 Serine/threonine protein kinase
Length = 441
Score = 114 bits (286), Expect = 3e-25
Identities = 83/268 (30%), Positives = 128/268 (46%), Gaps = 25/268 (9%)
Query: 174 RCLGEGAYGXXXXXXXXXXXXXYAMKQLKKAEILISEDSIEKDANTTVEKRIERTFAERT 233
R LG G + AMK + K EK + +I+R E +
Sbjct: 28 RLLGHGTFAKVYHARNIQTGKSVAMKVVGK----------EKVVKVGMVDQIKR---EIS 74
Query: 234 ILSQLEHPNIVKLFYSFHDNHKLYLVLQYIPGGELFYHLKEQGTLDEGTVAFYAAELSCA 293
++ ++HPNIV+L K+Y ++ + GGELF + + G L E Y +L A
Sbjct: 75 VMRMVKHPNIVELHEVMASKSKIYFAMELVRGGELFAKVAK-GRLREDVARVYFQQLISA 133
Query: 294 LKFLHSKGIVYRDLKPENCLLNERGHLVLTDFGLSKKSVFDDAATPEEGENVNQLYSIIG 353
+ F HS+G+ +RDLKPEN LL+E G+L +TDFGLS A E + L++ G
Sbjct: 134 VDFCHSRGVYHRDLKPENLLLDEEGNLKVTDFGLS--------AFTEHLKQDGLLHTTCG 185
Query: 354 TPEYCAPEILAGEPYT-QNCDWYSLGCLVYDMLIGKPPFTGVNHKIILNKIKQEKTGARI 412
TP Y APE++ + Y D +S G +++ +L G PF N + KI + +
Sbjct: 186 TPAYVAPEVILKKGYDGAKADLWSCGVILFVLLAGYLPFQDDNLVNMYRKI--YRGDFKC 243
Query: 413 PSYLSDGFKDYLGALLRKDPTKRWDVDK 440
P +LS + + LL +P R ++K
Sbjct: 244 PGWLSSDARRLVTKLLDPNPNTRITIEK 271
>At1g09000 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 666
Score = 114 bits (286), Expect = 3e-25
Identities = 82/297 (27%), Positives = 143/297 (47%), Gaps = 22/297 (7%)
Query: 145 SSVEETRQLRASSFSKTGAPRVLDDFVPI-----RCLGEGAYGXXXXXXXXXXXXXYAMK 199
S + +++ SFS +D PI + +G GA+G A+K
Sbjct: 39 SCIRKSKIFIKPSFSPPPPANTVDMAPPISWRKGQLIGRGAFGTVYMGMNLDSGELLAVK 98
Query: 200 QLKKAEILISEDSIEKDANTTVEKRIERTFAERTILSQLEHPNIVKLFYSFHDNHKLYLV 259
Q +LI+ + K+ + I+ E +L L HPNIV+ + ++ L ++
Sbjct: 99 Q-----VLIAANFASKEKT---QAHIQELEEEVKLLKNLSHPNIVRYLGTVREDDTLNIL 150
Query: 260 LQYIPGGELFYHLKEQGTLDEGTVAFYAAELSCALKFLHSKGIVYRDLKPENCLLNERGH 319
L+++PGG + L++ G E V Y +L L++LH+ I++RD+K N L++ +G
Sbjct: 151 LEFVPGGSISSLLEKFGPFPESVVRTYTRQLLLGLEYLHNHAIMHRDIKGANILVDNKGC 210
Query: 320 LVLTDFGLSKKSVFDDAATPEEGENVNQLYSIIGTPEYCAPEILAGEPYTQNCDWYSLGC 379
+ L DFG SK+ E + S+ GTP + APE++ ++ + D +S+GC
Sbjct: 211 IKLADFGASKQVA--------ELATMTGAKSMKGTPYWMAPEVILQTGHSFSADIWSVGC 262
Query: 380 LVYDMLIGKPPFTGVNHKI-ILNKIKQEKTGARIPSYLSDGFKDYLGALLRKDPTKR 435
V +M+ GK P++ ++ + I K+ IP LS KD+L L++ P R
Sbjct: 263 TVIEMVTGKAPWSQQYKEVAAIFFIGTTKSHPPIPDTLSSDAKDFLLKCLQEVPNLR 319
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.317 0.136 0.400
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,863,733
Number of Sequences: 60738
Number of extensions: 1408149
Number of successful extensions: 8293
Number of sequences better than 1.0e-05: 1651
Number of HSP's better than 0.0 without gapping: 510
Number of HSP's successfully gapped in prelim test: 1142
Number of HSP's that attempted gapping in prelim test: 4765
Number of HSP's gapped (non-prelim): 1891
length of query: 556
length of database: 30,389,216
effective HSP length: 111
effective length of query: 445
effective length of database: 23,647,298
effective search space: 10523047610
effective search space used: 10523047610
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)