ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI6623 good U KOG0565 Intracellular trafficking, secretion, and vesicular transport Inositol polyphosphate 5-phosphatase and related proteins
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI6623 2304733 2305860 376
(376 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YOL065c [U] KOG0565 Inositol polyphosphate 5-phosphatase and rel... 185 1e-46
SPBC2G2.02 [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (... 100 3e-21
YIL002c [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (syn... 86 9e-17
YOR109w [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (syn... 81 3e-15
At2g01900 [U] KOG0565 Inositol polyphosphate 5-phosphatase and r... 79 1e-14
SPBC577.13 [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (... 78 2e-14
7290234 [U] KOG0565 Inositol polyphosphate 5-phosphatase and rel... 78 2e-14
YNL106c [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (syn... 76 9e-14
7302845 [U] KOG0565 Inositol polyphosphate 5-phosphatase and rel... 74 4e-13
SPAC9G1.10c [U] KOG0565 Inositol polyphosphate 5-phosphatase and... 72 2e-12
Hs13325072 [U] KOG0565 Inositol polyphosphate 5-phosphatase and ... 72 2e-12
Hs13325070 [U] KOG0565 Inositol polyphosphate 5-phosphatase and ... 72 2e-12
7291368 [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (syn... 71 3e-12
7293245 [U] KOG0565 Inositol polyphosphate 5-phosphatase and rel... 70 4e-12
Hs5031799 [U] KOG0565 Inositol polyphosphate 5-phosphatase and r... 69 9e-12
Hs20537935 [U] KOG0565 Inositol polyphosphate 5-phosphatase and ... 69 9e-12
At1g71710 [U] KOG0565 Inositol polyphosphate 5-phosphatase and r... 69 1e-11
ECU10g1370 [U] KOG0565 Inositol polyphosphate 5-phosphatase and ... 67 6e-11
Hs14747866 [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (... 65 1e-10
At1g34120 [U] KOG0565 Inositol polyphosphate 5-phosphatase and r... 65 1e-10
7294594 [U] KOG0565 Inositol polyphosphate 5-phosphatase and rel... 65 1e-10
Hs22045277 [U] KOG0565 Inositol polyphosphate 5-phosphatase and ... 65 2e-10
Hs4507335 [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (s... 64 3e-10
Hs4755142_1 [U] KOG0565 Inositol polyphosphate 5-phosphatase and... 64 3e-10
CE29050 [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (syn... 63 8e-10
CE28239 [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (syn... 63 8e-10
At1g05470 [U] KOG0565 Inositol polyphosphate 5-phosphatase and r... 63 8e-10
At2g37440 [U] KOG0565 Inositol polyphosphate 5-phosphatase and r... 62 1e-09
CE28690 [U] KOG0565 Inositol polyphosphate 5-phosphatase and rel... 62 1e-09
At2g32010 [U] KOG0565 Inositol polyphosphate 5-phosphatase and r... 62 2e-09
At4g18010 [U] KOG0565 Inositol polyphosphate 5-phosphatase and r... 61 2e-09
Hs18765709 [U] KOG0565 Inositol polyphosphate 5-phosphatase and ... 60 5e-09
At3g63240 [U] KOG0565 Inositol polyphosphate 5-phosphatase and r... 59 1e-08
At2g43900 [U] KOG0565 Inositol polyphosphate 5-phosphatase and r... 56 1e-07
At1g65580 [U] KOG0565 Inositol polyphosphate 5-phosphatase and r... 55 2e-07
At2g31830 [U] KOG0565 Inositol polyphosphate 5-phosphatase and r... 53 8e-07
Hs9845291 [U] KOG0565 Inositol polyphosphate 5-phosphatase and r... 52 1e-06
At1g47510 [U] KOG0565 Inositol polyphosphate 5-phosphatase and r... 51 2e-06
At1g05630 [U] KOG0565 Inositol polyphosphate 5-phosphatase and r... 51 3e-06
CE17405 [U] KOG0565 Inositol polyphosphate 5-phosphatase and rel... 50 4e-06
At5g04980 [U] KOG0565 Inositol polyphosphate 5-phosphatase and r... 50 5e-06
Hs18765707 [U] KOG0565 Inositol polyphosphate 5-phosphatase and ... 49 9e-06
CE00123 [U] KOG0565 Inositol polyphosphate 5-phosphatase and rel... 49 9e-06
>YOL065c [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 384
Score = 185 bits (469), Expect = 1e-46
Identities = 126/390 (32%), Positives = 198/390 (50%), Gaps = 37/390 (9%)
Query: 6 KVFASSFNCAKVFPFDDIDTQKSILEQL-------IPHVSHHDIYILGFQELMSIWQGSF 58
KV ++FNC K FP ++ K+I++QL I + D+Y+LGFQE++ IWQGSF
Sbjct: 7 KVSVTTFNCGKEFP---VENSKAIVKQLLFPYDDGISQLELQDLYVLGFQEVVPIWQGSF 63
Query: 59 SNICFQYLEGLSKLVLNRINTE------ETTFKCVDINCLGAIGLMV-FCKEELEV-TNI 110
+ ++ ++ +N +N + + + C+ +N LGAI ++V + L+V +I
Sbjct: 64 PAVNRDLIDRITTTAVNCLNEKVSATQGDEQYSCLGVNSLGAITIIVLYNNNALKVKDDI 123
Query: 111 LKTNVKCGVFYSSLKGASVIRFSILHEGVS--DTITCVTSHLAANEGLINLEKRIQDYHA 168
LK N KCG F + LKG ++I F + G + + + +HL ANEG+ N +RI DY
Sbjct: 124 LKRNGKCGWFGTHLKGGTLISFQMTRNGEENWERFSYICAHLNANEGVNNRNQRIDDYKR 183
Query: 169 IMSSLRNEFGEMELSHVIFTGDLNFRLNKFFG-DVDYRDPDIISQLLNENDELRDVMK-- 225
IMS + + + H F GDLNFR+ + +Y + +LL ++EL + K
Sbjct: 184 IMSEVCDS-EVAKSDHFFFLGDLNFRVTSTYDPTTNYSSTTTLRRLLENHEELNLLRKGE 242
Query: 226 SERAFTQFLEPSIQFPPTFKYNISSPKDDIAQDPLYYNFKRQPSWCDRILYSN--ISKDA 283
E F E I FPPT+K+ + + YN KR PSWCDRILY + + A
Sbjct: 243 DEPLCKGFQELKITFPPTYKFKLFEKET--------YNTKRIPSWCDRILYKSYAVPTFA 294
Query: 284 KPTLYKAIPRTEIFHFTDHQPVILSIELPHIEPPNITRGVXXXXXXXXXXXXXXXXFGRM 343
+ Y ++PR+ F+DHQPV L++ LP + + G++
Sbjct: 295 QEGTYHSVPRSNALLFSDHQPVNLTVRLPRSTGTPVPLSL---HIEKYPLSWSSGLIGQI 351
Query: 344 VDYIIGYSGWLYFKHSRMGLLVLVLFSIYL 373
D +IGY GWL K+ +L +L + L
Sbjct: 352 GDAVIGYCGWLVTKNVHYWILGSLLLYLLL 381
>SPBC2G2.02 [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (synaptojanin)
INP51/INP52/INP53 family
Length = 1076
Score = 100 bits (250), Expect = 3e-21
Identities = 94/318 (29%), Positives = 145/318 (45%), Gaps = 36/318 (11%)
Query: 3 RTLKVFASSFNCAKVFPFDDIDTQKSILEQLIP-HVSHHDIYILGFQELMSIWQG---SF 58
+ +K+F +S+N + + L P + DIY++GFQE++ + S
Sbjct: 556 KNVKIFVASYN------LNGCSATTKLENWLFPENTPLADIYVVGFQEIVQLTPQQVISA 609
Query: 59 SNICFQYLEGLSKLVLNRINTEETTFKCVDINCLGAIGLMVFCKEEL--EVTNILKTNVK 116
+ E K +LN T + + L LM+FCKE + N+ T K
Sbjct: 610 DPAKRREWESCVKRLLNGKCTSGPGYVQLRSGQLVGTALMIFCKESCLPSIKNVEGTVKK 669
Query: 117 CGVF-YSSLKGASVIRFSILHEGVSDTITC-VTSHLAANEGLINLEKRIQDYHAIMSSLR 174
G+ S KGA IRF DT C +TSHLAA G N ++R DY I S LR
Sbjct: 670 TGLGGVSGNKGAVAIRFDY-----EDTGLCFITSHLAA--GYTNYDERDHDYRTIASGLR 722
Query: 175 NEFGEMELSH--VIFTGDLNFRLNKFFGDVDYRDPDIISQLLNENDELRDVMKSERAFTQ 232
G +H V++ GD N+R++ + +V L E D+L M + + F
Sbjct: 723 FRRGRSIFNHDYVVWFGDFNYRISLTYEEVVPCIAQGKLSYLFEYDQLNKQMLTGKVFPF 782
Query: 233 FLEPSIQFPPTFKYNISSPKDDIAQDPLYYNFKRQPSWCDRILYSNISKDAKPTLYKAIP 292
F E I FPPT+K++I + D + R P+W DRILY + P Y+++P
Sbjct: 783 FSELPITFPPTYKFDIGTDIYDTSDK------HRVPAWTDRILYRG---ELVPHSYQSVP 833
Query: 293 RTEIFHFTDHQPVILSIE 310
+++DH+P+ + E
Sbjct: 834 ----LYYSDHRPIYATYE 847
>YIL002c [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (synaptojanin)
INP51/INP52/INP53 family
Length = 946
Score = 85.9 bits (211), Expect = 9e-17
Identities = 90/311 (28%), Positives = 140/311 (44%), Gaps = 27/311 (8%)
Query: 3 RTLKVFASSFNCAKVFPFDDIDTQKSILEQLIPHVSHHDIYILGFQELMSIWQGSFSNIC 62
+ + +FA +FN + P DDI + + D+Y++G +E++ + G
Sbjct: 525 KDISIFAGTFNISGKIPKDDIKDW-IFPKSMSKEDEMADLYVIGLEEVVELTPGHMLATD 583
Query: 63 FQYLEGLSKLVLNRINTEETTFKCVDI--NCLGAIGLMVFCKE-ELEVTNILKTNVKCGV 119
+ K +L +N K + + LG I L++F E E ++ +VK
Sbjct: 584 PYVRQFWEKKILTLLNGPGRKKKYIRLWSTQLGGILLLLFMNETEYSKVKHIEGDVKKTG 643
Query: 120 F--YSSLKGASVIRFSILHEGVSDTITCV-TSHLAANEGLINLEKRIQDYHAIMSSLRNE 176
F +S KGA + F S T CV SHLAA GL N+E+R DY I S+R
Sbjct: 644 FGGMASNKGAVAVSFKY-----SATRFCVLVSHLAA--GLENVEQRHNDYKTIAKSIRFS 696
Query: 177 FGEMELSH--VIFTGDLNFRLNKFFGDVDYRDPDIISQLLNENDELRDVMKSERAFTQFL 234
G H +I+ GD N+R+ DV + L E D+L M + +F F
Sbjct: 697 KGLRIKDHDAIIWMGDFNYRILMSNEDVRRKIVSKEYASLFEKDQLNQQMIAGESFPYFH 756
Query: 235 EPSIQFPPTFKYNISSPKDDIAQDPLYYNFKRQPSWCDRILYSNISKDAKPTLYKAIPRT 294
E +I FPPT+K++ + D ++ R P+W DRIL + + + YK
Sbjct: 757 EMAIDFPPTYKFDPGTKNYDTSEK------MRIPAWTDRIL--SRGEVLEQLEYKC---C 805
Query: 295 EIFHFTDHQPV 305
E F+DH+PV
Sbjct: 806 EDILFSDHRPV 816
>YOR109w [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (synaptojanin)
INP51/INP52/INP53 family
Length = 1107
Score = 80.9 bits (198), Expect = 3e-15
Identities = 76/280 (27%), Positives = 128/280 (45%), Gaps = 40/280 (14%)
Query: 41 DIYILGFQELMSIWQGSFSNICFQYLEGLSKLVLNRINTEETTFKCVDINCLGAIGLMVF 100
DI +LG QE++ + GS N + LV + +N + + + + + ++ ++ F
Sbjct: 598 DIVVLGLQEVIELSAGSILNADYSKSSFWENLVGDCLNQYDDKYLLLRVEQMTSLLILFF 657
Query: 101 CKEELE--VTNILKTNVKCGVF-YSSLKGASVIRFSILHEGVSDTITCVTSHLAANEGLI 157
K + V + K G + KGA IRF E + + V SHLAA G
Sbjct: 658 VKADKAKYVKQVEGATKKTGFRGMAGNKGAVSIRF----EYGATSFCFVNSHLAA--GAT 711
Query: 158 NLEKRIQDYHAIMSSLRNEFGEMELSH--VIFTGDLNFRLNKFFGDVDYRDPDIISQLLN 215
N+E+R DY +I+ + +M H + + GD+N+R+N + D+ +LLN
Sbjct: 712 NVEERRSDYESIVRGITFTRTKMIPHHDSIFWLGDMNYRIN-------LPNEDVRRELLN 764
Query: 216 EN----------DELRDVMKSERAFTQFLEPSIQFPPTFKYNISSPKDDIAQDPLYYNFK 265
+ D+L + S F F EP+++F PT+KY+ + D ++ +
Sbjct: 765 QEEGYIDKLLHFDQLTLGINSGSVFEGFKEPTLKFRPTYKYDPGTGTYDSSEK------E 818
Query: 266 RQPSWCDRILYSNISKDAKPTLYKAIPRTEIFHFTDHQPV 305
R PSW DRI+Y ++ P Y P +DH+PV
Sbjct: 819 RTPSWTDRIIYK--GENLLPLSYSDAP----IMISDHRPV 852
>At2g01900 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 417
Score = 78.6 bits (192), Expect = 1e-14
Identities = 93/334 (27%), Positives = 146/334 (42%), Gaps = 52/334 (15%)
Query: 6 KVFASSFNCAKVFPFDDIDTQKSILEQLIPHVSHHDIYILGFQELMSIWQ----GSFSNI 61
KVF S++N + P D +D + + L H + DIY+LGFQE++ + GS +N
Sbjct: 59 KVFVSTWNVGGIVPDDGLDME----DLLETHKTPCDIYVLGFQEVVPLRASNVLGSDNNK 114
Query: 62 CFQYLEGLSKLVLNR---------------INTEETTFKCVDINCLGAIGLMVFCKEEL- 105
L + LN+ IN F+C+ + I + V+ + +L
Sbjct: 115 VSTKWNSLIRDALNKRARPHRDEDLSESKGINGISQDFRCIISKQMVGILITVWVRGDLW 174
Query: 106 -EVTNILKTNVKCGVFYS-SLKGASVIRFSILHEGVSDTITCVTSHLAANEGLINLEKRI 163
+ + V CG+ KG+ +RF LHE T V SHLA+ + +R
Sbjct: 175 PYIRYPSVSCVGCGIMGCLGNKGSVSVRFQ-LHE---TTFCFVCSHLASGGRDRDERQRN 230
Query: 164 QDYHAIM--------SSLRNEFGEMELSHVIFTGDLNFRLNKFFGDVDYRDPDIISQLLN 215
D + I+ SSL ++ VIF GDLN+R++ +L
Sbjct: 231 SDVNEILARSSFPRGSSLDLPKKILDHDRVIFLGDLNYRISLPEEKTRLLVESKKWNILL 290
Query: 216 ENDELRDVMKSERAFTQFLEPSIQFPPTFKYNISSPKDDIAQDPLYY---NFKRQPSWCD 272
END+LR + + + F + E ++F PT+KY P D+ + Y KR P+WCD
Sbjct: 291 ENDQLRMEIMNGQIFRGWQEGIVKFAPTYKY---VPNSDLYYGCITYKKDEKKRAPAWCD 347
Query: 273 RIL-YSNISKDAKPTLYKAIPRTEIFHFTDHQPV 305
RI+ Y N K + T + +DH+PV
Sbjct: 348 RIIWYGNGLKQHEYTRGET-------KISDHRPV 374
>SPBC577.13 [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (synaptojanin)
INP51/INP52/INP53 family
Length = 889
Score = 78.2 bits (191), Expect = 2e-14
Identities = 83/320 (25%), Positives = 147/320 (45%), Gaps = 32/320 (10%)
Query: 1 MSRTLKVFASSFNCAKVFPFDDIDTQKSILEQLIPHVSHHDIYILGFQELMSIWQGSFSN 60
+ R +F+S+FN P D K +L S +D+Y++ QE++++ +
Sbjct: 564 VERDFSIFSSTFNANGKVP--STDEFKRLLLPFGERTSAYDLYVVAVQEIITLNMSHLVS 621
Query: 61 ICFQYLEGLSKLVLNRINTEETTFKCVDINCLGAIGLM--VFCKEE--LEVTNILKTNVK 116
Q L + +L +N+ ++ K + I+ + G+ VF +++ L V+ + KT K
Sbjct: 622 SSNQKLRIWEEKILMILNSRDSNNKYMLISSIQMAGVFLGVFIRKDDHLVVSKVTKTTRK 681
Query: 117 CGVF-YSSLKGASVIRFSILHEGVSDTITC-VTSHLAANEGLINLEKRIQDYHAIMSSLR 174
G +S+ KGA I + V D+ C V+SH A N+ +R +Y +I +L
Sbjct: 682 TGFGGFSANKGAVAIEMN-----VCDSDFCFVSSHFAPKVN--NISERNMEYTSISDNLV 734
Query: 175 NEFGEMELSH--VIFTGDLNFRLNKFFGDV-DYRDPDIISQLLNENDELRDVMKSERAFT 231
G H +++ GD N+R++ +V + D + +L + D+L MK F
Sbjct: 735 FPSGMKIYDHTNILWMGDFNYRIDSDNEEVRKLVELDDLDKLASY-DQLCTEMKKGTVFH 793
Query: 232 QFLEPSIQFPPTFKYNISSPKDDIAQDPLYYNFKRQPSWCDRILYSNISKDAKPTLYKAI 291
+EP + F PT+K++ + D + +R PSW DRIL +K YK+
Sbjct: 794 GLVEPQLTFLPTYKFDNGTNDYDTSDK------QRVPSWTDRIL---ATKSFTRNCYKSC 844
Query: 292 PRTEIFHFTDHQPVILSIEL 311
+DH+PV + L
Sbjct: 845 D----IRCSDHRPVFATFSL 860
>7290234 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 850
Score = 78.2 bits (191), Expect = 2e-14
Identities = 76/278 (27%), Positives = 137/278 (48%), Gaps = 36/278 (12%)
Query: 41 DIYILGFQELMSIWQGSFSNICFQYLEG--LSKLVLNRINTEETTFKCVDINCLGAIGLM 98
DIY +G QEL + + ++ Q +E + K+ ++ ++ + ++ + + L A L
Sbjct: 218 DIYAIGLQELDTPTKAMLNSTQVQAIEKQWIDKM-MDSVHPD-VEYEILMSHRLVATMLT 275
Query: 99 VFCKEELE--VTNILKTNVKCGVFYSSLKGASVIRFSILHEGVSDTITCVTSHLAANEGL 156
V +++L + +V G+F + V L+EG I V SHLAA+ G
Sbjct: 276 VIVRKQLRQHIIRCRPKSVARGIFNTLGNKGGVAISLQLNEG---NICFVNSHLAAHMGY 332
Query: 157 INLEKRIQDYHAIMSSLRNEFGEM--ELSHVIFTGDLNFRLNKFFGDVDYRDPDIIS--- 211
+ E+R QDY+AI+ +R + G + H+ + GDLN+R+ + G + P +S
Sbjct: 333 V--EERNQDYNAIVEGIRFDDGRTISDHDHIFWVGDLNYRIQEPPGQ---QRPGPLSDAQ 387
Query: 212 --QLLNENDELRDVMKSERAFTQFLEPSIQFPPTFKYNISSPKDDIAQDPLYYNFKRQPS 269
+LL + D+LR M+ + F + E I+F PT+KY+ + D ++ +R P+
Sbjct: 388 TYELLLQYDQLRQEMRRGKCFEGYTEGEIKFRPTYKYDPGTDNYDSSEK------QRAPA 441
Query: 270 WCDRILYSNISKDAKPTLYKAIPRTEIFHF--TDHQPV 305
+CDR+L+ K T + + I +DH+PV
Sbjct: 442 YCDRVLW-------KGTRIEQLAYNSIMEIRQSDHKPV 472
>YNL106c [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (synaptojanin)
INP51/INP52/INP53 family
Length = 1183
Score = 75.9 bits (185), Expect = 9e-14
Identities = 71/277 (25%), Positives = 126/277 (44%), Gaps = 34/277 (12%)
Query: 41 DIYILGFQELMSIWQGSFSNICFQYLEGLSKLVLNRINTEETTFKCVDINCLGAIGLMVF 100
D+ +LG QE++ + GS N + +V + +N E + + + + ++ ++ F
Sbjct: 623 DVVVLGLQEVIELTAGSILNADYTKSSFWETMVTDCLNQYEEKYLLLRVEQMSSLLILFF 682
Query: 101 CKEEL-----EVTNILKTNVKCGVFYSSLKGASVIRFSILHEGVSDTITC-VTSHLAANE 154
+ + EV K G+ + KGA IRF T C V +HL+A
Sbjct: 683 ARSDRAYNIKEVGGSTKKTGFGGI--TGNKGAVAIRFDY-----GATSFCFVNTHLSA-- 733
Query: 155 GLINLEKRIQDYHAIMSSLRNEFGEMELSH--VIFTGDLNFRL----NKFFGDVDYRDPD 208
G N+++R DY+ I ++ + H + + GDLN+R+ ++ ++ +
Sbjct: 734 GASNIDERRNDYNNIYRNITFPRSKTIPHHDSLFWLGDLNYRITLTNDEVRRELRAQKDG 793
Query: 209 IISQLLNENDELRDVMKSERAFTQFLEPSIQFPPTFKYNISSPKDDIAQDPLYYNFKRQP 268
I +LL + D+L + F F EP++QF PT+KY+ + D ++ R P
Sbjct: 794 YIDRLL-QYDQLTQEINEGVVFQGFKEPTLQFRPTYKYDYGTDNYDTSEK------ARTP 846
Query: 269 SWCDRILYSNISKDAKPTLYKAIPRTEIFHFTDHQPV 305
SW DRI+Y ++ P Y P +DH+PV
Sbjct: 847 SWTDRIIYK--GENLHPLAYSDAP----LKISDHKPV 877
>7302845 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 357
Score = 73.9 bits (180), Expect = 4e-13
Identities = 82/283 (28%), Positives = 129/283 (44%), Gaps = 44/283 (15%)
Query: 41 DIYILGFQELMSIWQGSFSNICFQYLEGLSKLVLNRINTEETTFKCVDINCLGAIGLMVF 100
DIY++GFQE+ + Q + ++ + + F VD L I + +F
Sbjct: 48 DIYVIGFQEVSTTPQ------VLKIFNDDPWVLKIADSLSDHQFVKVDSKQLQGILITMF 101
Query: 101 CKEE----LEVTNILKTNVKCGVFYSSLKGASVIRFSILHEGVSDTITCVTSHLAANEGL 156
+ + ++ T G + + KGA IR S+ GV+ V SHLAA++
Sbjct: 102 AQHKHIPHMKEIETEATRTGLGGLWGN-KGAVSIRLSLYGTGVA----FVCSHLAAHDE- 155
Query: 157 INLEKRIQDYHAIMSSLR-NEFGEMEL---SHVIFTGDLNFRLNKFFGDVDYRDPDIISQ 212
L++RI+DYH I+ + + N G + V + GDLNFRL+ D R D+ +Q
Sbjct: 156 -KLKERIEDYHQIVDNHKYNAQGYRRIFDHDFVFWFGDLNFRLSGDMSAWDVRT-DVENQ 213
Query: 213 L---LNENDELRDVMKSERAFTQFLEPSIQFPPTFKYNISSPKDDIAQDPLYYNFKRQPS 269
L + D+L + + AF+ E F PTFK+ + D YN KR+P+
Sbjct: 214 RYADLLKLDQLNLLREKGNAFSLLEEQQPNFAPTFKF-VEGTND--------YNLKRRPA 264
Query: 270 WCDRIL-------YSNISKDAKPTLYKAIPRTEIFHFTDHQPV 305
WCDRIL Y I+ A Y++ + +DH+PV
Sbjct: 265 WCDRILHRVQSNIYPGITLSANQLSYQS---HMDYTLSDHKPV 304
>SPAC9G1.10c [U] KOG0565 Inositol polyphosphate 5-phosphatase and related proteins
Length = 1191
Score = 71.6 bits (174), Expect = 2e-12
Identities = 90/319 (28%), Positives = 136/319 (42%), Gaps = 62/319 (19%)
Query: 5 LKVFASSFNCAKVFPFD-DIDT-QKSILEQLIPHVSHHDIYILGFQELMSI--------- 53
+ + S+N P D D DT S++ +I + DI + GFQEL+ +
Sbjct: 789 VSILICSWNAGASKPSDLDSDTIGASMIPMMIRDNGYPDIVVFGFQELVDLENKRLTARS 848
Query: 54 ---------WQGSFSNICFQYLEGLSKLV--LNRINTEETTFKCVDINCLGAIGLMVFCK 102
+ +NI QY KL + R+++ + V N +G VF K
Sbjct: 849 ILSKSSSKGGSSNSANISSQYRLWREKLESEMMRVSSNDDYQVLVCENLVGLFSC-VFVK 907
Query: 103 EELE--VTNILKTNVKCGVF-YSSLKGASVIRFSILHEGVSDTITCVTS-HLAANEGLIN 158
+L+ + + T VK G+ KGA V+RF V DT C+ + HLAA + N
Sbjct: 908 NKLQSKIRMLQSTTVKTGLGGLHGNKGAIVVRFL-----VDDTSYCIVNCHLAAGQS--N 960
Query: 159 LEKRIQDYHAIMSSLR-----------NEF-----GEMELSH--VIFTGDLNFRLNKFFG 200
R D I+ + N F G + + H + GDLN+R+N
Sbjct: 961 KAARNNDLATILDNASLFPENDETDQLNTFVGGGDGSLIMDHEVCVLHGDLNYRINTLRP 1020
Query: 201 D-VDYRDPDIISQLLNENDELRDVMKSERAFT--QFLEPSIQFPPTFKYNISSPKDDIAQ 257
+D + I LL ++D+L K F F EP I F PT+KY++ S + D ++
Sbjct: 1021 KALDLIKKNDIKTLL-QSDQLLVERKRNAGFRLRTFTEPEITFAPTYKYDVHSEQYDSSE 1079
Query: 258 DPLYYNFKRQPSWCDRILY 276
KR P+WCDRI Y
Sbjct: 1080 K------KRVPAWCDRICY 1092
>Hs13325072 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 901
Score = 71.6 bits (174), Expect = 2e-12
Identities = 73/256 (28%), Positives = 119/256 (45%), Gaps = 42/256 (16%)
Query: 41 DIYILGFQELMSIWQGSFSNICFQYLEGLSK----LVLNRINTEETTFKCVDINCLGAIG 96
DIY +GFQEL S F Y E + + + + R + +K V + L +
Sbjct: 270 DIYCIGFQEL------DLSTEAFFYFESVKEQEWSMAVERGLHSKAKYKKVQLVRLVGMM 323
Query: 97 LMVFCKEEL--EVTNILKTNVKCGVFYS-SLKGASVIRFSILHEGVSDTITCVTSHLAAN 153
L++F +++ + +I V G+ KG +RF + H + T V SHLAA+
Sbjct: 324 LLIFARKDQCRYIRDIATETVGTGIMGKMGNKGGVAVRF-VFH---NTTFCIVNSHLAAH 379
Query: 154 EGLINLEKRIQDYHAIMSSLR--------NEFGEMELSHVIFTGDLNFRL-----NKFFG 200
+ + E+R QDY I + + + M+ VI+ GDLN+RL N+
Sbjct: 380 --VEDFERRNQDYKDICARMSFVVPNQTLPQLNIMKHEVVIWLGDLNYRLCMPDANEVKS 437
Query: 201 DVDYRDPDIISQLLNENDELRDVMKSERAFTQFLEPSIQFPPTFKYNISSPKDDIAQDPL 260
++ +D Q L + D+L ++AF F E I+F PT+KY+ + + D +
Sbjct: 438 LINKKD----LQRLLKFDQLNIQRTQKKAFVDFNEGEIKFIPTYKYDSKTDRWDSS---- 489
Query: 261 YYNFKRQPSWCDRILY 276
R P+WCDRIL+
Sbjct: 490 --GKCRVPAWCDRILW 503
>Hs13325070 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 893
Score = 71.6 bits (174), Expect = 2e-12
Identities = 73/256 (28%), Positives = 119/256 (45%), Gaps = 42/256 (16%)
Query: 41 DIYILGFQELMSIWQGSFSNICFQYLEGLSK----LVLNRINTEETTFKCVDINCLGAIG 96
DIY +GFQEL S F Y E + + + + R + +K V + L +
Sbjct: 270 DIYCIGFQEL------DLSTEAFFYFESVKEQEWSMAVERGLHSKAKYKKVQLVRLVGMM 323
Query: 97 LMVFCKEEL--EVTNILKTNVKCGVFYS-SLKGASVIRFSILHEGVSDTITCVTSHLAAN 153
L++F +++ + +I V G+ KG +RF + H + T V SHLAA+
Sbjct: 324 LLIFARKDQCRYIRDIATETVGTGIMGKMGNKGGVAVRF-VFH---NTTFCIVNSHLAAH 379
Query: 154 EGLINLEKRIQDYHAIMSSLR--------NEFGEMELSHVIFTGDLNFRL-----NKFFG 200
+ + E+R QDY I + + + M+ VI+ GDLN+RL N+
Sbjct: 380 --VEDFERRNQDYKDICARMSFVVPNQTLPQLNIMKHEVVIWLGDLNYRLCMPDANEVKS 437
Query: 201 DVDYRDPDIISQLLNENDELRDVMKSERAFTQFLEPSIQFPPTFKYNISSPKDDIAQDPL 260
++ +D Q L + D+L ++AF F E I+F PT+KY+ + + D +
Sbjct: 438 LINKKD----LQRLLKFDQLNIQRTQKKAFVDFNEGEIKFIPTYKYDSKTDRWDSS---- 489
Query: 261 YYNFKRQPSWCDRILY 276
R P+WCDRIL+
Sbjct: 490 --GKCRVPAWCDRILW 503
>7291368 [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (synaptojanin)
INP51/INP52/INP53 family
Length = 1218
Score = 70.9 bits (172), Expect = 3e-12
Identities = 78/292 (26%), Positives = 135/292 (45%), Gaps = 34/292 (11%)
Query: 41 DIYILGFQELMSIWQGSFSNICFQYLEGLSKLV--LNRINTEETTFKCVDINCLGAIGLM 98
DIY +GF+E++ + + SNI + L + + + + + L + L
Sbjct: 593 DIYAIGFEEIVDL---NASNIMAASTDNAKLWAEELQKTISRDNDYVLLTYQQLVGVCLY 649
Query: 99 VFCKEEL--EVTNILKTNVKCGVFYSS-LKGASVIRFSILHEGVSDTITCVTSHLAANEG 155
++ + E + ++ VK G+ ++ KGA IRF +LH G S C +H AA +
Sbjct: 650 IYIRPEHAPHIRDVAIDCVKTGLGGATGNKGACAIRF-VLH-GTSMCFVC--AHFAAGQS 705
Query: 156 LINLEKRIQDYHAIMSSLRNEFGEMELSH--VIFTGDLNFRLNKFFGDVD--YRDPDIIS 211
+ +R DY I L G SH V + GD N+R++ ++ R+ D+ +
Sbjct: 706 QV--AERNADYAEITRKLAFPMGRTLKSHDWVFWCGDFNYRIDMEKDELKECVRNGDLST 763
Query: 212 QLLNENDELRDVMKSERAFTQFLEPSIQFPPTFKYNISSPKDDIAQDPLYYNFKRQPSWC 271
L E D+LR ++ F +FLE I F PT+KY++ S D ++ +R P+W
Sbjct: 764 VL--EFDQLRKEQEAGNVFGEFLEGEITFDPTYKYDLFSDDYDTSEK------QRAPAWT 815
Query: 272 DRILYSNISKDAKPTL-YKAIPRTEIFHF-------TDHQPVILSIELPHIE 315
DR+L+ A+ A ++ H+ +DH+PVI I+ +E
Sbjct: 816 DRVLWRRRKALAEGDFAASAWNPGKLIHYGRSELKQSDHRPVIAIIDAEIME 867
>7293245 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 508
Score = 70.5 bits (171), Expect = 4e-12
Identities = 57/211 (27%), Positives = 105/211 (49%), Gaps = 31/211 (14%)
Query: 125 KGASVIRFSILHEGVSDTITCVTSHLAANEGLINLEKRIQDYHAIMSSLR---NEFGEM- 180
KGA +RF++ G++ V +HL A++ + +++RI+DY I+ + + E+
Sbjct: 157 KGAVSVRFTLYGCGLA----FVVAHLTAHDHM--MDERIEDYKQILENHHYHVKRYREIY 210
Query: 181 ELSHVIFTGDLNFRLNKFFGDVDYRD---PDIISQLLNENDELRDVM-KSERAFTQFLEP 236
+ +V + GDLNFRL + R+ + + L + D+L V KS+ AF E
Sbjct: 211 DHDYVFWFGDLNFRLQGSDSSTEVRELVRDESQHEALIQRDQLYQVREKSQLAFQVLQER 270
Query: 237 SIQFPPTFKYNISSPKDDIAQDPLYYNFKRQPSWCDRILYSNISKDAKPTLYKAIPRTE- 295
FPPTFK+ + + Y+ KR+P+W DRI+Y+ + +P + +I +
Sbjct: 271 LPAFPPTFKFREGTSE---------YDLKRRPAWTDRIMYAVQPLNRQPGMQLSIEQCSY 321
Query: 296 ----IFHFTDHQPVILSIEL---PHIEPPNI 319
++ +DH+PV + P++ P +
Sbjct: 322 KSHPLYTISDHKPVTSDFTIKLYPNVRAPGV 352
>Hs5031799 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 1188
Score = 69.3 bits (168), Expect = 9e-12
Identities = 75/298 (25%), Positives = 132/298 (44%), Gaps = 59/298 (19%)
Query: 40 HDIYILGFQELMSIWQGSFSNICFQYLEGLSKLVLNRINTEETTFKCVDINCLGAIGLMV 99
HDIY++G QE + + + I L+ ++ + TFK V I+ L I ++V
Sbjct: 443 HDIYVIGTQE-DPLSEKEWLEILKHSLQEITSV----------TFKTVAIHTLWNIRIVV 491
Query: 100 FCKEELE--VTNILKTNVKCGVFYSSLKGASVIRFSILHEGVSDTITCVTSHLAANEGLI 157
K E E +++I NVK G+ ++L + S + G S + V SHL +
Sbjct: 492 LAKPEHENRISHICTDNVKTGIA-NTLGNKGAVGVSFMFNGTS--LGFVNSHLTSGS--- 545
Query: 158 NLEKRIQDYHAIMSSLRN-EFGEMELS---------HVIFTGDLNFRLNKFFGDVDYRDP 207
EK+++ M+ LR G+ +LS H+ + GDLN+R+ D+ +
Sbjct: 546 --EKKLRRNQNYMNILRFLALGDKKLSPFNITHRFTHLFWFGDLNYRV-----DLPTWEA 598
Query: 208 DIISQLLNE--------NDELRDVMKSERAFTQFLEPSIQFPPTFKYNISSPKDDIAQDP 259
+ I Q + + +D+L + ++ F F E I F PT+++ + + +D
Sbjct: 599 ETIIQKIKQQQYADLLSHDQLLTERREQKVFLHFEEEEITFAPTYRF------ERLTRDK 652
Query: 260 LYYNFKRQ-------PSWCDRILYSNISKDAKPTLYKAIPRTEIFHFTDHQPVILSIE 310
Y ++ PSWCDR+L+ S + ++ T +DH PV + E
Sbjct: 653 YAYTKQKATGMKYNLPSWCDRVLWK--SYPLVHVVCQSYGSTSDIMTSDHSPVFATFE 708
>Hs20537935 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 799
Score = 69.3 bits (168), Expect = 9e-12
Identities = 75/298 (25%), Positives = 132/298 (44%), Gaps = 59/298 (19%)
Query: 40 HDIYILGFQELMSIWQGSFSNICFQYLEGLSKLVLNRINTEETTFKCVDINCLGAIGLMV 99
HDIY++G QE + + + I L+ ++ + TFK V I+ L I ++V
Sbjct: 54 HDIYVIGTQE-DPLSEKEWLEILKHSLQEITSV----------TFKTVAIHTLWNIRIVV 102
Query: 100 FCKEELE--VTNILKTNVKCGVFYSSLKGASVIRFSILHEGVSDTITCVTSHLAANEGLI 157
K E E +++I NVK G+ ++L + S + G S + V SHL +
Sbjct: 103 LAKPEHENRISHICTDNVKTGIA-NTLGNKGAVGVSFMFNGTS--LGFVNSHLTSGS--- 156
Query: 158 NLEKRIQDYHAIMSSLRN-EFGEMELS---------HVIFTGDLNFRLNKFFGDVDYRDP 207
EK+++ M+ LR G+ +LS H+ + GDLN+R+ D+ +
Sbjct: 157 --EKKLRRNQNYMNILRFLALGDKKLSPFNITHRFTHLFWFGDLNYRV-----DLPTWEA 209
Query: 208 DIISQLLNE--------NDELRDVMKSERAFTQFLEPSIQFPPTFKYNISSPKDDIAQDP 259
+ I Q + + +D+L + ++ F F E I F PT+++ + + +D
Sbjct: 210 ETIIQKIKQQQYADLLSHDQLLTERREQKVFLHFEEEEITFAPTYRF------ERLTRDK 263
Query: 260 LYYNFKRQ-------PSWCDRILYSNISKDAKPTLYKAIPRTEIFHFTDHQPVILSIE 310
Y ++ PSWCDR+L+ S + ++ T +DH PV + E
Sbjct: 264 YAYTKQKATGMKYNLPSWCDRVLWK--SYPLVHVVCQSYGSTSDIMTSDHSPVFATFE 319
>At1g71710 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 655
Score = 68.9 bits (167), Expect = 1e-11
Identities = 70/227 (30%), Positives = 109/227 (47%), Gaps = 38/227 (16%)
Query: 97 LMVFCKEELE--VTNILKTNVKCGVF-YSSLKGASVIRFSILHEGVSDTITC-VTSHLAA 152
L ++ K L + N+ + V GV Y KGA + SI + T C + +HL A
Sbjct: 412 LTIWVKRSLRKHIQNVRVSTVGVGVMGYIGNKGAVSVSMSI-----NQTFFCFINTHLTA 466
Query: 153 NEGLINLEKRIQDYHAI--------MSSLRNEFGEMELSHVIFTGDLNFRLNKFFGDVDY 204
E ++ KR D H I +S+L + +I+ GDLN+RL+ +
Sbjct: 467 GEREVDQIKRNADVHEIHKRTVFHSVSALGLPKLIYDHERIIWLGDLNYRLSSSYE---- 522
Query: 205 RDPDIISQL----LNENDELRDVMKSERAFTQFLEPSIQFPPTFKYNISSPK--DDIAQD 258
+ D+IS+ L E D+L + RAF + E ++ FPPT+KY +S + + +
Sbjct: 523 KTRDLISKREWSKLLEYDQLVKEYRKGRAFDGWSEGTLHFPPTYKYQANSDEYTANDGKA 582
Query: 259 PLYYNFKRQPSWCDRILYSNISKDAKPTLYKAIPRTEIFHFTDHQPV 305
P KR P+WCDR+L + K + Y+ RTE F+DH+PV
Sbjct: 583 P-----KRTPAWCDRVL--SYGKGMRLVHYR---RTE-QKFSDHRPV 618
>ECU10g1370 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 322
Score = 66.6 bits (161), Expect = 6e-11
Identities = 64/249 (25%), Positives = 115/249 (45%), Gaps = 39/249 (15%)
Query: 63 FQYLEGLSKLVLNRINTEETTFKCVDINCLGAIGLMVFCKEELEVTNILKTNVKCGVFYS 122
F + G+ + VL ++K V + + + +V KE T ++K + F +
Sbjct: 40 FDFYSGVVRSVLKMY----PSYKMVSADRVLGLWSIVLSKER-HSTTVMKIGLGFLGFIN 94
Query: 123 SLKGASVIRFSILHEGVSDTITCVTSHLAANEGLINLEKRIQDYHAIMSSLRNEFGEMEL 182
KGA V R +S+ + ++ HL+A++ N +KR ++ + + +E +
Sbjct: 95 --KGACVTR-------ISNGVMFISCHLSAHQE--NSKKRQEEIRKVFECICDEESLKGI 143
Query: 183 SHVIFTGDLNFRLNKFFGDVDYRDPDIISQLLNENDELRDVMKSERAFTQFLEPSIQFPP 242
V+ GD+NFR++ +DY D+ + RA+ FLE I+F P
Sbjct: 144 DTVVLAGDMNFRVSGVPRALDY-------SRARPGDQCNEF---RRAYPTFLEEVIRFGP 193
Query: 243 TFKYNISSPKDDIAQDPLYYNFKRQPSWCDRILYSNISKDAKPTLYKAIPRTEIFHFTDH 302
T+KY + D++ + KR PSWCDR+ S+ S + Y +I +I +DH
Sbjct: 194 TYKYITGT--DELCR-------KRHPSWCDRVFVSS-SCTCRFNTYSSIHSVKI---SDH 240
Query: 303 QPVILSIEL 311
+PV+ E+
Sbjct: 241 KPVVCIFEV 249
>Hs14747866 [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (synaptojanin)
INP51/INP52/INP53 family
Length = 1496
Score = 65.5 bits (158), Expect = 1e-10
Identities = 73/300 (24%), Positives = 127/300 (42%), Gaps = 43/300 (14%)
Query: 41 DIYILGFQELMSIWQGSFSNICFQYLEGLSKLVLNRINTEETTFKCVDINCLGAIGLMVF 100
DI+ +GF+E++ + G+ N + + + I+ +G + L +F
Sbjct: 579 DIFAVGFEEMVELSAGNIVNASTTNKKMWGEQLQKAISRSHRYILLTSAQLVG-VCLYIF 637
Query: 101 CKEELE--VTNILKTNVKCGVF-YSSLKGASVIRFSILHEGVSDTITCVTSHLAANEGLI 157
+ + ++ VK G+ + KGA IRF S + + SHL A + +
Sbjct: 638 VRPYHVPFIRDVAIDTVKTGMGGKAGNKGAVGIRFQFH----STSFCFICSHLTAGQSQV 693
Query: 158 NLEKRIQDYHAIMSSLRNEFGEMELSH--VIFTGDLNFRLNKFFGDVDYRDPDIISQLLN 215
++R +DY I L G SH V + GD N+R++ + +V Y + L
Sbjct: 694 --KERNEDYKEITQKLCFPMGRNVFSHDYVFWCGDFNYRIDLTYEEVFYFVKRQDWKKLL 751
Query: 216 ENDELRDVMKSERAFTQFLEPSIQFPPTFKYNISSPKDDIAQDPLYYNFKRQPSWCDRIL 275
E D+L+ S + F F E +I F PT+KY++ S D + R P+W DR+L
Sbjct: 752 EFDQLQLQKSSGKIFKDFHEGAINFGPTYKYDVGSAAYDTSDK------CRTPAWTDRVL 805
Query: 276 Y------------------SNISKDAK------PTLYKAIPRTEIFHFTDHQPVILSIEL 311
+ S++ D K P + R E+ +DH+PV+ +E+
Sbjct: 806 WWRKKHPFDKTAGELNLLDSDLDVDTKVRHTWSPGALQYYGRAEL-QASDHRPVLAIVEV 864
>At1g34120 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 605
Score = 65.5 bits (158), Expect = 1e-10
Identities = 64/210 (30%), Positives = 99/210 (46%), Gaps = 25/210 (11%)
Query: 107 VTNILKTNVKCGVF-YSSLKGASVIRFSILHEGVSDTITC-VTSHLAANEGLINLEKRIQ 164
++N+ + V G+ Y KG+ + SI T C + +HL++ E + EKR
Sbjct: 378 ISNLCVSTVGVGIMGYIGNKGSVSVSMSIYQ-----TPFCFLCTHLSSGEKDTDQEKRND 432
Query: 165 DYHAIMSSLR--------NEFGEMELSH-VIFTGDLNFRLNKFFGDVDYRDPDIISQLLN 215
D I + NE +H +I+ GDLN+R+N + Q L
Sbjct: 433 DVREIHRRTQFLPHSLNANELPRSICNHEIIWLGDLNYRINLSYEKTHELIARKEWQRLV 492
Query: 216 ENDELRDVMKSERAFTQFLEPSIQFPPTFKYNISSPKDDIAQDPLYYNFKRQPSWCDRIL 275
E D+L M F + E ++ F PT+KY I S ++ I DP + KR+P+WCDRI+
Sbjct: 493 EYDQLSREMTKGNLFEGWSEGTLDFAPTYKYEIDS-ENYIGDDP--ESGKRRPAWCDRII 549
Query: 276 YSNISKDAKPTLYKAIPRTEIFHFTDHQPV 305
++ K K Y+ R EI +DH+PV
Sbjct: 550 WN--GKGMKLFNYR---RNEI-KLSDHRPV 573
>7294594 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 747
Score = 65.5 bits (158), Expect = 1e-10
Identities = 56/207 (27%), Positives = 95/207 (45%), Gaps = 35/207 (16%)
Query: 92 LGAIGLMVFCKEEL----EVTNILKTNVKCGVFYSSLKGASVIRFSILHEGVSDTITCVT 147
LG + L V+ + +L V +V+ G + + KGA I F + ++ VT
Sbjct: 459 LGTLHLAVYMRRDLIWYCSVPEDASMSVRTGSAFRT-KGAVAISFCLF----GTSMLFVT 513
Query: 148 SHLAANEGLINLEKRIQDYHAIMSSL-----------RNEFGEMELSHVIFTGDLNFRLN 196
SHL A++ + ++R+ D I+++L +N+ +V + GDLNFRL
Sbjct: 514 SHLTAHQQKV--KERVSDVKRIINALDLPRNLPNQRHKNKDVTQNFDNVFWCGDLNFRLG 571
Query: 197 K-------FFGDVDYRDPDIISQLLNENDELRDVMKSERAFTQFLEPSIQFPPTFKYNIS 249
+ + + + P + D+L V+ AF F+E +I FPPT+KY+
Sbjct: 572 EPREKLLEWIQNTKFPLPSHLPHGYMHTDQLTSVLADGAAFRGFMEANITFPPTYKYDPG 631
Query: 250 SPKDDIAQDPLYYNFKRQPSWCDRILY 276
S D + +R P++ DRILY
Sbjct: 632 SQNFDTSSK------QRAPAYTDRILY 652
>Hs22045277 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 652
Score = 65.1 bits (157), Expect = 2e-10
Identities = 76/281 (27%), Positives = 130/281 (46%), Gaps = 39/281 (13%)
Query: 41 DIYILGFQELMSIWQGSFSNICFQYLEGLSKLVLNRINTEETTFKCVDINCLGAIGLMVF 100
D+Y +GFQEL + F + + E K V ++ + K I +G I L+++
Sbjct: 295 DVYCVGFQELDLSKEAFFFHDTPKEEEWF-KAVSEGLHPDAKYAKVKLIRLVG-IMLLLY 352
Query: 101 CKEE--LEVTNILKTNVKCGVF-YSSLKGASVIRFSILHEGVSDTITCVTSHLAANEGLI 157
K+E ++ + V G+ KG IRF + +I V SHLAA+ +
Sbjct: 353 VKQEHAAYISEVEAETVGTGIMGRMGNKGGVAIRFQFHNT----SICVVNSHLAAH--IE 406
Query: 158 NLEKRIQDYHAIMSSLR-----NEFGEMELSH---VIFTGDLNFRLNKFFGDVD-----Y 204
E+R QDY I S ++ + +S+ +++ GDLN+R+ + DV+
Sbjct: 407 EYERRNQDYKDICSRMQFCQPDPSLPPLTISNHDVILWLGDLNYRIEEL--DVEKVKKLI 464
Query: 205 RDPDIISQLLNENDELRDVMKSERAFTQFLEPSIQFPPTFKYNISSPKDDIAQDPLYYNF 264
+ D Q+L D+L+ + ++ F F E + F PT+KY+ S D ++
Sbjct: 465 EEKDF--QMLYAYDQLKIQVAAKTVFEGFTEGELTFQPTYKYDTGSDDWDTSEK------ 516
Query: 265 KRQPSWCDRILYSNISKDAKPTLYKAIPRTEIFHFTDHQPV 305
R P+WCDRIL+ K+ Y++ + +DH+PV
Sbjct: 517 CRAPAWCDRILWK--GKNITQLSYQSHMALKT---SDHKPV 552
>Hs4507335 [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (synaptojanin)
INP51/INP52/INP53 family
Length = 1575
Score = 64.3 bits (155), Expect = 3e-10
Identities = 74/311 (23%), Positives = 137/311 (43%), Gaps = 57/311 (18%)
Query: 41 DIYILGFQELMSIWQGSFSNICFQYLEGLSKLVLNRINTEETTFKCVDINCLGAIGLMVF 100
DI+ +GF+E++ + G+ + + L + L + + + + + L + L VF
Sbjct: 583 DIFAIGFEEMVELNAGNIVSASTTN-QKLWAVELQKTISRDNKYVLLASEQLVGVCLFVF 641
Query: 101 CKEELE--VTNILKTNVKCGVFYSS-LKGASVIRFSILHEGVSDTITCVTSHLAANEGLI 157
+ + + ++ VK G+ ++ KGA IR + H + ++ V SH AA + +
Sbjct: 642 IRPQHAPFIRDVAVDTVKTGMGGATGNKGAVAIRM-LFH---TTSLCFVCSHFAAGQSQV 697
Query: 158 NLEKRIQDYHAIMSSLRNEFGEMELSH--VIFTGDLNFRLNKFFGDVDYRDPDIISQLLN 215
++R +D+ I L G M SH V + GD N+R +D + ++ +
Sbjct: 698 --KERNEDFIEIARKLSFPMGRMLFSHDYVFWCGDFNYR-------IDLPNEEVKELIRQ 748
Query: 216 EN-------DELRDVMKSERAFTQFLEPSIQFPPTFKYNISSPKDDIAQDPLYYNFKRQP 268
+N D+L + + + F FLE + F PT+KY++ S D ++ R P
Sbjct: 749 QNWDSLIAGDQLINQKNAGQVFRGFLEGKVTFAPTYKYDLFSDDYDTSEK------CRTP 802
Query: 269 SWCDRILYS----------------NIS-KDAKPTLYKAIPRTEIFHF-------TDHQP 304
+W DR+L+ N S +D LY P T + H+ +DH+P
Sbjct: 803 AWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKILYTWTPGT-LLHYGRAELKTSDHRP 861
Query: 305 VILSIELPHIE 315
V+ I++ E
Sbjct: 862 VVALIDIDIFE 872
>Hs4755142_1 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 1139
Score = 64.3 bits (155), Expect = 3e-10
Identities = 84/325 (25%), Positives = 142/325 (42%), Gaps = 39/325 (12%)
Query: 5 LKVFASSFNCAKVFPFDDID---TQKSILEQL--IPHVSHHDIYILGFQELMSIWQGSFS 59
+ VF ++N V P ++ T K + + L + HDIY+ G QE S+ +
Sbjct: 424 ISVFIGTWNMGSVPPPKNVTSWFTSKGLGKTLDEVTVTIPHDIYVFGTQE-NSVGDREWL 482
Query: 60 NICFQYLEGLSKLVLNRINTEETTFKCVDINCLGAIGLMVFCKEELE--VTNILKTNVKC 117
++ L+ L+ L ++ + + L I + V K E E ++++ ++VK
Sbjct: 483 DLLRGGLKELTDL----------DYRPIAMQSLWNIKVAVLVKPEHENRISHVSTSSVKT 532
Query: 118 GVFYSSLKGASVIRFSILHEGVSDTITCVTSHLAANEGLINLEKRIQDYHAIMSSLR--- 174
G+ ++L + S + G S V HL + G +R Q+Y I+ L
Sbjct: 533 GIA-NTLGNKGAVGVSFMFNGTS--FGFVNCHLTS--GNEKTARRNQNYLDILRLLSLGD 587
Query: 175 ---NEFG-EMELSHVIFTGDLNFRLNKFFGDV-DYRDPDIISQLLNENDELRDVMKSERA 229
N F + +H+ + GDLN+RL+ ++ +Y LL D+L + +
Sbjct: 588 RQLNAFDISLRFTHLFWFGDLNYRLDMDIQEILNYISRKEFEPLLRV-DQLNLEREKHKV 646
Query: 230 FTQFLEPSIQFPPTFKYNISSPKDDIA---QDPLYYNFKRQPSWCDRILYSNISKDAKPT 286
F +F E I FPPT++Y S +D A Q P PSWCDRIL+ S
Sbjct: 647 FLRFSEEEISFPPTYRYERGS-RDTYAWHKQKPTGVR-TNVPSWCDRILWK--SYPETHI 702
Query: 287 LYKAIPRTEIFHFTDHQPVILSIEL 311
+ + T+ +DH PV + E+
Sbjct: 703 ICNSYGCTDDIVTSDHSPVFGTFEV 727
>CE29050 [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (synaptojanin)
INP51/INP52/INP53 family
Length = 1119
Score = 62.8 bits (151), Expect = 8e-10
Identities = 60/232 (25%), Positives = 104/232 (43%), Gaps = 19/232 (8%)
Query: 79 TEETTFKCVDINCLGAIGLMVFCKEELE--VTNILKTNVKCGVFYSS-LKGASVIRFSIL 135
+E+ F + L + L +F + + + + +VK G+ ++ KG+ R +
Sbjct: 612 SEKAPFVLIGSEQLVGVCLFLFARPRVSPYLKDFAVASVKTGMGGATGNKGSVAFRIVVF 671
Query: 136 HEGVSDTITCVTSHLAANEGLINLEKRIQDYHAIMSSLRNEFGEMELSH--VIFTGDLNF 193
S +I + SH AA + + R +D+ + +R G SH + + GD N+
Sbjct: 672 ----STSICFICSHFAAGQN--EIRDRNEDFATTLKKIRFPLGREIDSHDVIFWLGDFNY 725
Query: 194 RLNKFFGDVDYRDPDIISQLLNENDELRDVMKSERAFTQFLEPSIQFPPTFKYNISSPKD 253
R+N +V + L END+L + F F E + F PT+KY+ S
Sbjct: 726 RINLSGDEVKNAVRNGDYAKLVENDQLTQQKALGQTFVGFNEGQLTFAPTYKYDTFSDDY 785
Query: 254 DIAQDPLYYNFKRQPSWCDRILYSNISKDAKPTLYKAIPRTEIFHFTDHQPV 305
D ++ R P+W DRIL+ + K K L + R+E+ +DH+PV
Sbjct: 786 DTSEK------CRAPAWTDRILWKDQRKKGKTQLL-SYDRSEL-KTSDHRPV 829
>CE28239 [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (synaptojanin)
INP51/INP52/INP53 family
Length = 1113
Score = 62.8 bits (151), Expect = 8e-10
Identities = 60/232 (25%), Positives = 104/232 (43%), Gaps = 19/232 (8%)
Query: 79 TEETTFKCVDINCLGAIGLMVFCKEELE--VTNILKTNVKCGVFYSS-LKGASVIRFSIL 135
+E+ F + L + L +F + + + + +VK G+ ++ KG+ R +
Sbjct: 606 SEKAPFVLIGSEQLVGVCLFLFARPRVSPYLKDFAVASVKTGMGGATGNKGSVAFRIVVF 665
Query: 136 HEGVSDTITCVTSHLAANEGLINLEKRIQDYHAIMSSLRNEFGEMELSH--VIFTGDLNF 193
S +I + SH AA + + R +D+ + +R G SH + + GD N+
Sbjct: 666 ----STSICFICSHFAAGQN--EIRDRNEDFATTLKKIRFPLGREIDSHDVIFWLGDFNY 719
Query: 194 RLNKFFGDVDYRDPDIISQLLNENDELRDVMKSERAFTQFLEPSIQFPPTFKYNISSPKD 253
R+N +V + L END+L + F F E + F PT+KY+ S
Sbjct: 720 RINLSGDEVKNAVRNGDYAKLVENDQLTQQKALGQTFVGFNEGQLTFAPTYKYDTFSDDY 779
Query: 254 DIAQDPLYYNFKRQPSWCDRILYSNISKDAKPTLYKAIPRTEIFHFTDHQPV 305
D ++ R P+W DRIL+ + K K L + R+E+ +DH+PV
Sbjct: 780 DTSEK------CRAPAWTDRILWKDQRKKGKTQLL-SYDRSEL-KTSDHRPV 823
>At1g05470 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 585
Score = 62.8 bits (151), Expect = 8e-10
Identities = 67/226 (29%), Positives = 104/226 (45%), Gaps = 31/226 (13%)
Query: 97 LMVFCKEELE--VTNILKTNVKCGVF-YSSLKGASVIRFSILHEGVSDTITCVTS----- 148
L ++ K EL V N+ + V G+ Y KG+ I + T +TS
Sbjct: 330 LTIWVKSELREHVKNMKVSCVGRGLMGYLGNKGSISISMLLHQTSFCFVCTHLTSGQKEG 389
Query: 149 -HLAANEGLINLEKRIQDYHAIMSSLRNEFGEMELSH--VIFTGDLNFRLNKFFGDVDYR 205
L N ++ + K+ + + + SS + E L H VI+ GDLN+R+ + YR
Sbjct: 390 DELKRNSDVMEILKKTR-FPRVKSSEEEKSPENILQHDRVIWLGDLNYRIA-----LSYR 443
Query: 206 DPDIISQLLN-----ENDELRDVMKSERAFTQFLEPSIQFPPTFKYNISSPKDDIAQDPL 260
+ ++ N END+LR K F + E I FPPT+KY+ +S D + D L
Sbjct: 444 SAKALVEMQNWRALLENDQLRIEQKRGHVFKGWNEGKIYFPPTYKYSRNS--DRYSGDDL 501
Query: 261 YYNFKRQ-PSWCDRILYSNISKDAKPTLYKAIPRTEIFHFTDHQPV 305
+ KR+ P+WCDRIL+ L++ F+DH+PV
Sbjct: 502 HPKEKRRTPAWCDRILWFG------EGLHQLSYVRGESRFSDHRPV 541
>At2g37440 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 401
Score = 62.4 bits (150), Expect = 1e-09
Identities = 71/242 (29%), Positives = 109/242 (44%), Gaps = 38/242 (15%)
Query: 95 IGLMVFCKEELE--VTNILKTNVKCGVF-YSSLKGASVIRFSILHEGVSDTITCVTSHLA 151
I L V+ +++L +TN+ + V G+ Y KG+ I S LHE ++ V +HL
Sbjct: 127 IFLCVWVRDDLRKRITNLKVSCVGRGIMGYLGNKGSVSISMS-LHE---TSLCFVCTHLT 182
Query: 152 ANEGLINLEKRIQDYHAIMSSLRNEFGE--------MELSHVIFTGDLNFRLNKFFGDVD 203
+ E + +R D I R M+ VI+ GDLN+RL
Sbjct: 183 SGEKEGDELRRNLDVTEIFKRTRFSRSSKDSRPETIMDHDKVIWLGDLNYRLRA------ 236
Query: 204 YRDPDIISQLLN-------ENDELRDVMKSERAFTQFLEPSIQFPPTFKYNISSPKDDIA 256
D+ QL N E D+L+ ++ R F + E I F PT+KY I+S + +
Sbjct: 237 --SSDLHEQLRNHDWESLLEKDQLKIEQRAGRIFKGWEEGKIYFAPTYKYRINS-DNYVV 293
Query: 257 QDPLYYNFKRQPSWCDRILYSNISKDAKPTLYKAIPRTEIFHFTDHQPVILSIELPHIEP 316
Q +R P+WCDRIL+ D L+ ++ F+DH+PV S+ HI+
Sbjct: 294 QTEKSKEKRRTPAWCDRILWKG---DGMKQLWYVRGESK---FSDHRPV-QSLFSVHIDL 346
Query: 317 PN 318
N
Sbjct: 347 KN 348
>CE28690 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 363
Score = 62.0 bits (149), Expect = 1e-09
Identities = 46/133 (34%), Positives = 69/133 (51%), Gaps = 28/133 (21%)
Query: 160 EKRIQDYHAIMSSLRNEFGEMELSH------------VIFTGDLNFRLNKFFGDVDYRDP 207
++RIQDY ++ +LR F ++ H V++ GDLNFR+ +VD+RDP
Sbjct: 175 QQRIQDYAKVVRTLR--FPQLARFHAHAKDEIFGSDVVLWIGDLNFRVT-VESNVDWRDP 231
Query: 208 DIISQL----LNENDELRDVMKSERAFTQFLEPSIQFPPTFKYNISSPKDDIAQDPLYYN 263
+ I++ + E +EL K + AFT F E I+FPPT K+ D Y
Sbjct: 232 EKITEKTFRDVFETEELASHRKKQLAFTDFKEAPIKFPPTHKFE---------PDTDNYV 282
Query: 264 FKRQPSWCDRILY 276
KR PS+ DR+L+
Sbjct: 283 PKRIPSFTDRVLF 295
>At2g32010 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 501
Score = 61.6 bits (148), Expect = 2e-09
Identities = 69/224 (30%), Positives = 103/224 (45%), Gaps = 32/224 (14%)
Query: 95 IGLMVFCKEELE--VTNILKTNVKCGVF-YSSLKGASVIRFSILHEGVSDTITCVTSHLA 151
I L ++ K EL V N+ + V G+ Y KG+ I S+L S C +HL
Sbjct: 253 IFLTIWVKSELREHVKNMKVSCVGRGLMGYLGNKGS--ISISMLLHQTSFCFVC--THLT 308
Query: 152 ANEGLINLEKRIQDYHAIMSSLRNEFGEMELS----HVIFTGDLNFRLNKFFGDVDYRDP 207
+ + + +R D I+ R F ++ S VI+ GDLN+R+ + YR
Sbjct: 309 SGQKEGDELRRNSDVMEILKKTR--FPRVQSSADENRVIWLGDLNYRIA-----LSYRSA 361
Query: 208 DIISQLLN-----ENDELRDVMKSERAFTQFLEPSIQFPPTFKYNISSPKDDIAQDPLYY 262
+ ++ N END+LR K F + E I FPPT+KY S+ D A L+
Sbjct: 362 KALVEMQNWRALLENDQLRIEQKRGHVFKGWNEGKIYFPPTYKY--SNNSDRYAGGDLHP 419
Query: 263 NFKRQ-PSWCDRILYSNISKDAKPTLYKAIPRTEIFHFTDHQPV 305
KR+ P+WCDRIL+ L++ F+DH+PV
Sbjct: 420 KEKRRTPAWCDRILWHG------EGLHQLSYVRGESRFSDHRPV 457
>At4g18010 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 595
Score = 61.2 bits (147), Expect = 2e-09
Identities = 45/127 (35%), Positives = 68/127 (53%), Gaps = 19/127 (14%)
Query: 185 VIFTGDLNFRLNKFFGDVDYRDPDIISQL----LNENDELRDVMKSERAFTQFLEPSIQF 240
V + GDLN+RLN G+V ++SQ L +D+L ++ F + E I+F
Sbjct: 446 VFWFGDLNYRLNMSDGEVR----KLVSQKRWDELKNSDQLIRELRRGHVFDGWREGPIKF 501
Query: 241 PPTFKYNISSPK--DDIAQDPLYYNFKRQPSWCDRILYSNISKDAKPTLYKAIPRTEIFH 298
PPT+KY S + + ++P KR P+WCDRIL+ + K + YK R+EI
Sbjct: 502 PPTYKYEFDSDRYAGENLREP---EKKRAPAWCDRILW--LGKGIRQECYK---RSEI-R 552
Query: 299 FTDHQPV 305
+DH+PV
Sbjct: 553 MSDHRPV 559
>Hs18765709 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 448
Score = 60.1 bits (144), Expect = 5e-09
Identities = 78/293 (26%), Positives = 129/293 (43%), Gaps = 50/293 (17%)
Query: 3 RTLKVFASSFNCAKVFPFDDIDTQKSILEQLIPHVSHHDIYILGFQELMS---------I 53
R L + ++N A P D+ S L QL + DIY++G QEL S
Sbjct: 12 RRLSIHVVTWNVASAAPPLDL----SDLLQLNNRNLNLDIYVIGLQELNSGIISLLSDAA 67
Query: 54 WQGSFSNICFQYLEGLSKLVLNRINTEETTFKCVDINCLGAIGLMVFCK-EELEVTNILK 112
+ S+S+ L LS + ++ + + I L+VF K + L IL
Sbjct: 68 FNDSWSSFLMDVLSPLSFIKVSHVRMQ-------------GILLLVFAKYQHLPYIQILS 114
Query: 113 T-NVKCGVF-YSSLKGASVIRFSILHEGVSDTITCVTSHLAANEGLINLEKRIQDYHAIM 170
T + G+F Y KG I + VS + HL + + N +R++ + I+
Sbjct: 115 TKSTPTGLFGYWGNKGGVNICLKLYGYYVS----IINCHLPPH--ISNNYQRLEHFDRIL 168
Query: 171 SSLRNEFGEME--LSH--VIFTGDLNFRLNKFFGDVDYRDPDIISQL---LNENDELRDV 223
E ++ L H +I+ GD+NFR+ F + + I ++ L E D+L
Sbjct: 169 EMQNCEGRDIPNILDHDLIIWFGDMNFRIEDF--GLHFVRESIKNRCYGGLWEKDQLSIA 226
Query: 224 MKSERAFTQFLEPSIQFPPTFKYNISSPKDDIAQDPLYYNFKRQPSWCDRILY 276
K + +F E + FPPT+K++ +S D ++ KR+P+W DRIL+
Sbjct: 227 KKHDPLLREFQEGRLLFPPTYKFDRNSNDYDTSEK------KRKPAWTDRILW 273
>At3g63240 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 574
Score = 58.9 bits (141), Expect = 1e-08
Identities = 76/243 (31%), Positives = 112/243 (45%), Gaps = 47/243 (19%)
Query: 95 IGLMVFCKEELE--VTNILKTNVKCGVF-YSSLKGASVIRFSILHEGVSDTITC-VTSHL 150
I L V+ K +L V N+ + V G+ Y KG+ I S V T C V SHL
Sbjct: 289 IFLTVWVKSDLRDSVNNLKVSCVGRGLMGYLGNKGSISISMS-----VHQTSFCFVCSHL 343
Query: 151 AANEGLINLEKRIQDYHAIMSSLR----NEFGE-------MELSHVIFTGDLNFRLNKFF 199
+ + + +R D I+ R N G+ E VI+ GDLN+R+
Sbjct: 344 TSGQKEGDELRRNSDVLEILRKTRFPRVNNAGDDKSPQMISEHDRVIWLGDLNYRIA--- 400
Query: 200 GDVDYRDPDIISQL-----LNENDELRDVMKSERAFTQFLEPSIQFPPTFKYNISSPKDD 254
+ YR + ++ L E D+LR + F + E +I FPPT+KY+ +S D
Sbjct: 401 --LSYRSAKALVEMRDWRALLEKDQLRIEQRKGCVFEGWKEGTIYFPPTYKYSNNS---D 455
Query: 255 I--AQDPLYYNFKRQPSWCDRILY--SNISKDAKPTLYKAIPRTEIFHFTDHQPV--ILS 308
I D L +R P+WCDRIL+ S IS+ + R E F+DH+PV + S
Sbjct: 456 IYAGDDRLPKAKRRTPAWCDRILWHGSGISQ-------LSYVRGE-SRFSDHRPVYSLFS 507
Query: 309 IEL 311
+E+
Sbjct: 508 VEI 510
>At2g43900 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 1305
Score = 55.8 bits (133), Expect = 1e-07
Identities = 44/133 (33%), Positives = 59/133 (44%), Gaps = 29/133 (21%)
Query: 151 AANEGLINLEKRIQDYHAIMSSLRNEFGEMELSHVIFTGDLNFRLNKFFGDVDYRDPDII 210
+AN +N E+ QD E V+F GD N+RL FG D +
Sbjct: 769 SANNANVNTEETKQDL-------------AEADMVVFFGDFNYRL---FGISYDEARDFV 812
Query: 211 SQL----LNENDELRDVMKSERAFTQFLEPSIQFPPTFKYNISSP---KDDIAQDPLYYN 263
SQ L E D+LR MK+ R F E I FPPT+K+ P D +
Sbjct: 813 SQRSFDWLREKDQLRAEMKAGRVFQGMREAIITFPPTYKFERHRPGLGGYDSGEK----- 867
Query: 264 FKRQPSWCDRILY 276
KR P+WCDR+++
Sbjct: 868 -KRIPAWCDRVIF 879
>At1g65580 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 993
Score = 55.1 bits (131), Expect = 2e-07
Identities = 42/116 (36%), Positives = 57/116 (48%), Gaps = 20/116 (17%)
Query: 174 RNEFGEMELSHVIFTGDLNFRLNKFFGDVDYRDP-DIISQL----LNENDELRDVMKSER 228
R E E ++ VIF GD N+RL+ D+ Y + D ISQ L E D+L M++
Sbjct: 634 RPELSEADM--VIFLGDFNYRLD----DITYDETRDFISQRCFDWLREKDQLHTEMEAGN 687
Query: 229 AFTQFLEPSIQFPPTFKY---NISSPKDDIAQDPLYYNFKRQPSWCDRILYSNISK 281
F E I+FPPT+K+ D + KR P+WCDRILY + K
Sbjct: 688 VFQGMREAIIRFPPTYKFERHQAGLAGYDSGEK------KRIPAWCDRILYRDNKK 737
>At2g31830 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 1144
Score = 52.8 bits (125), Expect = 8e-07
Identities = 41/115 (35%), Positives = 51/115 (43%), Gaps = 22/115 (19%)
Query: 175 NEFGEMELSH------VIFTGDLNFRLNKFFGDVDYRDPDIISQL----LNENDELRDVM 224
N E E SH V F GD N+RL FG D IS L E D+LR M
Sbjct: 777 NNSTEEEKSHLASADLVAFFGDFNYRL---FGITYDEARDFISHRSFDWLREKDQLRQEM 833
Query: 225 KSERAFTQFLEPSIQFPPTFKYNISSP---KDDIAQDPLYYNFKRQPSWCDRILY 276
+ F E I FPPT+K+ + P D + KR P+WCDR++Y
Sbjct: 834 NEGKVFQGMREALITFPPTYKFEKNKPGLGGYDSGEK------KRIPAWCDRVIY 882
>Hs9845291 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 644
Score = 52.0 bits (123), Expect = 1e-06
Identities = 53/199 (26%), Positives = 86/199 (42%), Gaps = 33/199 (16%)
Query: 125 KGASVIRFSILHEGVSDTITCVTSHLAANEGLINLEKRIQDYHAIMSSL----------- 173
KGA I F+ + +TSH + +G + +R+ DY + +L
Sbjct: 404 KGALGISFTFF----GTSFLFITSHFTSGDGKV--AERLLDYTRTVQALVLPRNVPDTNP 457
Query: 174 -RNEFGEM--ELSHVIFTGDLNFRLNKFFGDVDY---RDPDIISQLLNENDELRDVMKSE 227
R+ ++ V + GD NFRL+ VD + + L ++D+L M+
Sbjct: 458 YRSSAADVTTRFDEVFWFGDFNFRLSGGRTVVDALLCQGLVVDVPALLQHDQLIREMRKG 517
Query: 228 RAFTQFLEPSIQFPPTFKYNISSPKDDIAQDPLYYNFKRQPSWCDRILYSNISK-DAKPT 286
F F EP I F P++K++I D +R PS+ DR+LY + K D P
Sbjct: 518 SIFKGFQEPDIHFLPSYKFDIGKDTYDSTSK------QRTPSYTDRVLYRSRHKGDICPV 571
Query: 287 LYKAIPRTEIFHFTDHQPV 305
Y + P + +DH+PV
Sbjct: 572 SYSSCPGIKT---SDHRPV 587
>At1g47510 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 331
Score = 51.2 bits (121), Expect = 2e-06
Identities = 45/190 (23%), Positives = 85/190 (44%), Gaps = 14/190 (7%)
Query: 117 CGVFYSSLKGASVIRFSILHEGVSDTITCVTSHLAANEGLINLEKRIQDYHAIMSSLRNE 176
CG KGA IR + ++ + + ++ HL+A+ ++ ++ + H S L +
Sbjct: 144 CGGLIGRKKGAVAIRIN--YDDIK--MVFISCHLSAHAKKVD-QRNTELRHIANSLLPRD 198
Query: 177 FGEMELSHVIFTGDLNFRLNKFFGD-VDYRDPDIISQLLNENDELRDVMKSERAFTQFLE 235
+ +L+ ++ GDLN+R+ V + + +L D+L + F + E
Sbjct: 199 KRKRDLT--VWLGDLNYRIQDVSNHPVRSLIQNHLQSVLVSKDQLLQEAERGEIFKGYSE 256
Query: 236 PSIQFPPTFKYNISSPKDDIAQDPLYYNFKRQPSWCDRILYSNISKDAKPTLYKAIPRTE 295
++ F PT+KYN+ S D + R P+W DRIL+ D + +
Sbjct: 257 GTLGFKPTYKYNVGSSDYDTSHK------IRVPAWTDRILFKIQDTDNIQATLHSYDSID 310
Query: 296 IFHFTDHQPV 305
+ +DH+PV
Sbjct: 311 QVYGSDHKPV 320
>At1g05630 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 1136
Score = 50.8 bits (120), Expect = 3e-06
Identities = 38/98 (38%), Positives = 48/98 (48%), Gaps = 14/98 (14%)
Query: 185 VIFTGDLNFRLNKFFGDVDYRDPDIISQL----LNENDELRDVMKSERAFTQFLEPSIQF 240
V F GD N+RL FG D ISQ L E D+LR MK + F E I F
Sbjct: 784 VAFFGDFNYRL---FGITYDEARDFISQRSFDWLRERDQLRAEMKVGKVFQGMREALITF 840
Query: 241 PPTFKY--NISSPKDDIAQDPLYYNFKRQPSWCDRILY 276
PPT+K+ N S + + KR P+WCDR++Y
Sbjct: 841 PPTYKFERNRSGLGGYDSGEK-----KRIPAWCDRVIY 873
>CE17405 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 753
Score = 50.4 bits (119), Expect = 4e-06
Identities = 78/298 (26%), Positives = 120/298 (40%), Gaps = 50/298 (16%)
Query: 41 DIYILGFQELMSIWQGSFSNICFQYLEGLSKLVLNRINTEETTFKCVDINCLGAIGLMVF 100
+ Y +G QE M + G++ + +EG + + T F V L I ++VF
Sbjct: 126 EFYAVGLQE-MDLSVGTYIIDNTKKMEGWVDAIHCSLPGGRTQFNVVGSMRLVGIFVIVF 184
Query: 101 ----CKEELEVTNILKTNVKCGVFYSSL--KGASVIRFSILHEGVSDTITC-VTSHLAAN 153
K + N+ V + L KG + + + +DT C V +H AA
Sbjct: 185 QAVNSKVRVSDVNVKYVATGISVLVNKLGNKGGTAVSMKM-----NDTWVCFVNAHFAAG 239
Query: 154 EGLINLEKRIQDYHAIMSS-----------LRNEFGEMEL------SHVIFTGDLNFRLN 196
LE+R QD+ I + LR+ E+ + V + GDLN+RLN
Sbjct: 240 NN--ELERRNQDFRDIYNDMVFYPRSQQEGLRDRPLEVPIMCLYDHDVVFWFGDLNYRLN 297
Query: 197 KFFGDVD------YRDPDIISQLLNENDELRDVMKSERAFTQFLEPS-IQFPPTFKYNIS 249
+ D + LL ++ +LR+ M F F EPS + F PT+KY+
Sbjct: 298 TDMYGISNDEVRRIASSDKFADLL-QHCQLREQMARGTVFKDFEEPSTLPFRPTYKYDCG 356
Query: 250 SPKDDIAQDPLYYNFKRQPSWCDRILYSNISKDAKPTLYKAIPRTEIFHFT--DHQPV 305
+ D ++ R P+W DRIL K + L P I T DH+PV
Sbjct: 357 TNTWDTSEK------GRVPAWTDRIL--TFKKYPQVGLESIRPMVSIDTITISDHKPV 406
>At5g04980 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 366
Score = 50.1 bits (118), Expect = 5e-06
Identities = 51/172 (29%), Positives = 79/172 (45%), Gaps = 19/172 (11%)
Query: 146 VTSHLAANEGLINLEKRIQDYHAIMSSL------RNEFGEM-----ELSHVIFTGDLNFR 194
+ SHLA+ E + +R D I+ + R F + + VI+ GDLN+R
Sbjct: 182 ICSHLASGEREGDERRRNLDVIEILKNTSFPRICRTSFTRVPDRITKHDRVIWLGDLNYR 241
Query: 195 LNKFFGDVD-YRDPDIISQLLNENDELRDVMKSERAFTQFLEPSIQFPPTFKYNISSPKD 253
+ + + D + LLN+ D+L+ + R F + E I F PT+KY+ +S
Sbjct: 242 IALSYSETKTLLDKNAWDTLLNK-DQLKIERDAGRVFKGWHEGKIFFAPTYKYSYNSDAY 300
Query: 254 DIAQDPLYYNFKRQPSWCDRILYSNISKDAKPTLYKAIPRTEIFHFTDHQPV 305
N +R P+WCDRIL+ D L + R E F+DH+PV
Sbjct: 301 AGDTSKEKKNKRRTPAWCDRILWHG---DGIRQL--SYVRGE-SRFSDHRPV 346
>Hs18765707 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 372
Score = 49.3 bits (116), Expect = 9e-06
Identities = 54/190 (28%), Positives = 90/190 (46%), Gaps = 24/190 (12%)
Query: 97 LMVFCK-EELEVTNILKT-NVKCGVF-YSSLKGASVIRFSILHEGVSDTITCVTSHLAAN 153
L+VF K + L IL T + G+F Y KG I + VS + HL +
Sbjct: 22 LLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICLKLYGYYVS----IINCHLPPH 77
Query: 154 EGLINLEKRIQDYHAIMSSLRNEFGEME--LSH--VIFTGDLNFRLNKFFGDVDYRDPDI 209
+ N +R++ + I+ E ++ L H +I+ GD+NFR+ F + + I
Sbjct: 78 --ISNNYQRLEHFDRILEMQNCEGRDIPNILDHDLIIWFGDMNFRIEDF--GLHFVRESI 133
Query: 210 ISQL---LNENDELRDVMKSERAFTQFLEPSIQFPPTFKYNISSPKDDIAQDPLYYNFKR 266
++ L E D+L K + +F E + FPPT+K++ +S D ++ KR
Sbjct: 134 KNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSNDYDTSEK------KR 187
Query: 267 QPSWCDRILY 276
+P+W DRIL+
Sbjct: 188 KPAWTDRILW 197
>CE00123 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 398
Score = 49.3 bits (116), Expect = 9e-06
Identities = 38/136 (27%), Positives = 61/136 (43%), Gaps = 14/136 (10%)
Query: 142 TITCVTSHLAANEGLINLEKRIQDYHAIMSSLRNEFGEMELSHVIFTGDLNFRLNKFFGD 201
+I V SH G N KR++ YH + E + + + GD NFR+ +
Sbjct: 129 SIVFVDSHFI--HGPENYGKRVEQYHTNRNCSFPE--DKSVRAAFWFGDFNFRVEEDVNT 184
Query: 202 VDYRDPDIIS-QLLNENDELRDVMKSERAFTQFLEPSIQFPPTFKYNISSPKDDIAQDPL 260
V + + +LL+ ++L+ + AF F E + F PT++ + + + D
Sbjct: 185 VIRKIKNGTHLELLDTREQLKRALVERDAFIGFHEQPVTFEPTYRVTVGTTEQD------ 238
Query: 261 YYNFKRQPSWCDRILY 276
KR PSW DRILY
Sbjct: 239 ---GKRVPSWTDRILY 251
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.324 0.141 0.427
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,229,060
Number of Sequences: 60738
Number of extensions: 937699
Number of successful extensions: 2832
Number of sequences better than 1.0e-05: 43
Number of HSP's better than 0.0 without gapping: 0
Number of HSP's successfully gapped in prelim test: 43
Number of HSP's that attempted gapping in prelim test: 2722
Number of HSP's gapped (non-prelim): 53
length of query: 376
length of database: 30,389,216
effective HSP length: 108
effective length of query: 268
effective length of database: 23,829,512
effective search space: 6386309216
effective search space used: 6386309216
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)