ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI6658 good R KOG0370 General function prediction only Multifunctional pyrimidine synthesis protein CAD (includes carbamoyl-phophate synthetase, aspartate transcarbamylase, and glutamine amidotransferase)
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI6658 2319027 2317801 -409
(409 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YOR303w [R] KOG0370 Multifunctional pyrimidine synthesis protein... 525 e-149
SPBC56F2.09c [R] KOG0370 Multifunctional pyrimidine synthesis pr... 424 e-119
Hs18105007 [R] KOG0370 Multifunctional pyrimidine synthesis prot... 317 2e-86
YJL130c [R] KOG0370 Multifunctional pyrimidine synthesis protein... 315 6e-86
SPAC22G7.06c [R] KOG0370 Multifunctional pyrimidine synthesis pr... 314 2e-85
CE03105 [R] KOG0370 Multifunctional pyrimidine synthesis protein... 302 7e-82
Hs21361331 [R] KOG0370 Multifunctional pyrimidine synthesis prot... 300 3e-81
HsM4503019 [R] KOG0370 Multifunctional pyrimidine synthesis prot... 296 3e-80
7293258 [R] KOG0370 Multifunctional pyrimidine synthesis protein... 283 4e-76
At3g27740 [R] KOG0370 Multifunctional pyrimidine synthesis prote... 207 3e-53
>YOR303w [R] KOG0370 Multifunctional pyrimidine synthesis protein CAD
(includes carbamoyl-phophate synthetase aspartate
transcarbamylase and glutamine amidotransferase)
Length = 411
Score = 525 bits (1352), Expect = e-149
Identities = 272/418 (65%), Positives = 315/418 (75%), Gaps = 26/418 (6%)
Query: 6 STAPKAKFAIYNNSNPDSESGFVEFQGYSFGAPVSCSGEAVFTTSLVGYPESMTDPSYKG 65
S A KA F I N + F+G SFGA S +GE VFTTSLVGYPESMTDPSY+G
Sbjct: 3 SAATKATFCIQNGPS---------FEGISFGANKSVAGETVFTTSLVGYPESMTDPSYRG 53
Query: 66 QILVFTQPLIGNYGVPSGEERDDFNLLKYLESPHIHVRGIVVAEYAWRYSHWTAVESLAT 125
QILVFTQPLIGNYGVPSGE RD++NLLKY ESPHIHV GIVVAEYA++YSHWTAVESLA
Sbjct: 54 QILVFTQPLIGNYGVPSGEARDEYNLLKYFESPHIHVVGIVVAEYAYQYSHWTAVESLAQ 113
Query: 126 WCQRENVTAIGGIDTRAVVQILREQGSSPSTITVQGSFIPKPIKP-ETDLVKIVSTKKPF 184
WCQRE V AI G+DTR +VQ LREQGSS IT+ + P +T+LV V+TKKPF
Sbjct: 114 WCQREGVAAITGVDTRELVQYLREQGSSLGRITLADHDPVPYVNPMKTNLVAQVTTKKPF 173
Query: 185 FVKALSSVKTPFNVALIDCGVKENIIRCLVERGANVTVFPYDYPITSVANQFDGIFISNG 244
V AL K NVALIDCGVKENIIRCLV+RGANVTVFPYDY I VA++FDGIF+SNG
Sbjct: 174 HVSALPG-KAKANVALIDCGVKENIIRCLVKRGANVTVFPYDYRIQDVASEFDGIFLSNG 232
Query: 245 PGDPVQCMESTVPELKKLLETNTLQDLPIFGICLGHQLLALASGGKTIKLGYGNRAHNIP 304
PG+P C ++T+ +++LL +PIFGICLGHQLLALASG T KL YGNRAHNIP
Sbjct: 233 PGNPELC-QATISNVRELLNNPVYDCIPIFGICLGHQLLALASGASTHKLKYGNRAHNIP 291
Query: 305 ALDLTTGQCHITSQNHGYAVDVDTLPESGFKPFFQNLNDKSNEGMIHVSRPIFSTQFHPE 364
A+DLTTGQCHITSQNHGYAVD +TLP+ +KP+F NLNDKSNEGMIH+ RPIFSTQFHPE
Sbjct: 292 AMDLTTGQCHITSQNHGYAVDPETLPKDQWKPYFVNLNDKSNEGMIHLQRPIFSTQFHPE 351
Query: 365 AKGGPRDSAVLFDRYFDNMSQYRALKGPKVKLTL--------------NTSSLATERV 408
AKGGP D+A+LFD++FDN+ +Y+ K ++L N + LA ERV
Sbjct: 352 AKGGPLDTAILFDKFFDNIEKYQLQSQAKSSISLKVTYSTDKSRLQSINVTKLAKERV 409
>SPBC56F2.09c [R] KOG0370 Multifunctional pyrimidine synthesis protein CAD
(includes carbamoyl-phophate synthetase aspartate
transcarbamylase and glutamine amidotransferase)
Length = 415
Score = 424 bits (1091), Expect = e-119
Identities = 218/363 (60%), Positives = 268/363 (73%), Gaps = 13/363 (3%)
Query: 30 FQGYSFGAPVSCSGEAVFTTSLVGYPESMTDPSYKGQILVFTQPLIGNYGVPSGEERDDF 89
F G SFGA + SGEAVFTTS VGY ES+TDPSYK QIL+FTQPLIGNYGVP ++RD+
Sbjct: 56 FHGTSFGANRNVSGEAVFTTSPVGYVESLTDPSYKQQILIFTQPLIGNYGVPDCKKRDEN 115
Query: 90 NLLKYLESPHIHVRGIVVAEYAWRYSHWTAVESLATWCQRENVTAIGGIDTRAVVQILRE 149
LL++ ESPHI G+VV +YA +YSHWTAVESL WC RE V AI G+DTRA+V LRE
Sbjct: 116 GLLRHFESPHIQCAGVVVNDYATKYSHWTAVESLGEWCAREGVAAITGVDTRAIVTFLRE 175
Query: 150 QGSSPSTITVQGSFIPKP----IKP-ETDLVKIVSTKKPFFVKALSSVKTPFNVALIDCG 204
QGSS + I++ + I P E +LV VST++PFFV + N+A+IDCG
Sbjct: 176 QGSSLAKISIGEEYDANDDEAFINPEEVNLVSQVSTREPFFVSGGDGM---LNIAVIDCG 232
Query: 205 VKENIIRCLVERGANVTVFPYDYPITSVANQFDGIFISNGPGDPVQCMESTVPELKKLLE 264
VKENI+R LV RGA+VTVFP+DYPI +VA+ +DGIF++NGPGDP + TV L++L+
Sbjct: 233 VKENILRSLVSRGASVTVFPFDYPIQNVASNYDGIFLTNGPGDPTH-LTKTVNNLRELMN 291
Query: 265 TNTLQDLPIFGICLGHQLLALASGGKTIKLGYGNRAHNIPALDLTTGQCHITSQNHGYAV 324
T + PI GIC+GHQLLAL++G KTIKL YGNR HNIPALD+ +G CHITSQNHGYAV
Sbjct: 292 T---YNGPIMGICMGHQLLALSTGAKTIKLKYGNRGHNIPALDIASGNCHITSQNHGYAV 348
Query: 325 DVDTLPESGFKPFFQNLNDKSNEGMIHVSRPIFSTQFHPEAKGGPRDSAVLFDRYFDNMS 384
D TLP + +K + NLND+SNEG+ HVSRPI S QFHPEA+GGP D+ LFD Y
Sbjct: 349 DASTLP-AEWKATWTNLNDQSNEGIAHVSRPISSVQFHPEARGGPMDTFYLFDNYIKEAI 407
Query: 385 QYR 387
+Y+
Sbjct: 408 KYQ 410
>Hs18105007 [R] KOG0370 Multifunctional pyrimidine synthesis protein CAD
(includes carbamoyl-phophate synthetase aspartate
transcarbamylase and glutamine amidotransferase)
Length = 2225
Score = 317 bits (812), Expect = 2e-86
Identities = 176/371 (47%), Positives = 234/371 (62%), Gaps = 21/371 (5%)
Query: 24 ESGFVEFQGYSFGAPVSCSGEAVFTTSLVGYPESMTDPSYKGQILVFTQPLIGNYGVPSG 83
E G V +G FGA VS +GE VF T +VGYPE++TDPSYK QILV T PLIGNYG+P
Sbjct: 7 EDGSV-LRGQPFGAAVSTAGEVVFQTGMVGYPEALTDPSYKAQILVLTYPLIGNYGIPP- 64
Query: 84 EERDDFNLLKYLESPHIHVRGIVVAEYAWRYSHWTAVESLATWCQRENVTAIGGIDTRAV 143
+E D+F L K+ ES IHV +VV E SHW+A +L W Q+ + + G+DTR +
Sbjct: 65 DEMDEFGLCKWFESSGIHVAALVVGECCPTPSHWSATRTLHEWLQQHGIPGLQGVDTREL 124
Query: 144 VQILREQGSSPSTITVQGS------FIPKPIKPETDLVKIVSTKKPFFVKALSSVKTPFN 197
+ LREQGS + G+ F+ +P LV VS K P + ++ P
Sbjct: 125 TKKLREQGSLLGKLVQNGTEPSSLPFLDPNARP---LVPEVSIKTP---RVFNTGGAPRI 178
Query: 198 VALIDCGVKENIIRCLVERGANVTVFPYDYPITSVANQFDGIFISNGPGDPVQCMESTVP 257
+AL DCG+K N IRCL +RGA VTV P+D+ + S +++G+F+SNGPGDP S V
Sbjct: 179 LAL-DCGLKYNQIRCLCQRGAEVTVVPWDHALDS--QEYEGLFLSNGPGDPAS-YPSVVS 234
Query: 258 ELKKLLETNTLQDLPIFGICLGHQLLALASGGKTIKLGYGNRAHNIPALDLTTGQCHITS 317
L ++L + P+FGICLGHQLLALA G KT K+ YGNR HN P L + +G+C +TS
Sbjct: 235 TLSRVLSEPNPR--PVFGICLGHQLLALAIGAKTYKMRYGNRGHNQPCLLVGSGRCFLTS 292
Query: 318 QNHGYAVDVDTLPESGFKPFFQNLNDKSNEGMIHVSRPIFSTQFHPEAKGGPRDSAVLFD 377
QNHG+AV+ D+LP + + P F N ND SNEG++H S P FS QFHPE + GP D +LFD
Sbjct: 293 QNHGFAVETDSLP-ADWAPLFTNANDGSNEGIVHNSLPFFSVQFHPEHQAGPSDMELLFD 351
Query: 378 RYFDNMSQYRA 388
+ + + + A
Sbjct: 352 IFLETVKEATA 362
>YJL130c [R] KOG0370 Multifunctional pyrimidine synthesis protein CAD
(includes carbamoyl-phophate synthetase aspartate
transcarbamylase and glutamine amidotransferase)
Length = 2214
Score = 315 bits (808), Expect = 6e-86
Identities = 173/386 (44%), Positives = 231/386 (59%), Gaps = 36/386 (9%)
Query: 31 QGYSFGAPVSCSGEAVFTTSLVGYPESMTDPSYKGQILVFTQPLIGNYGVPSGEERDDF- 89
QGYSFGA S +GE VF T +VGYPES+TDPSY+GQILV T PL+GNYGVP RD+
Sbjct: 33 QGYSFGAEKSVAGELVFQTGMVGYPESVTDPSYEGQILVITYPLVGNYGVPDMHLRDELV 92
Query: 90 -NLLKYLESPHIHVRGIVVAEYAWRYSHWTAVESLATWCQRENVTAIGGIDTRAVVQILR 148
L +Y ES IH+ G+V++ Y YSH+ SL W Q E + A+ G+DTR++ + LR
Sbjct: 93 EELPRYFESNRIHIAGLVISHYTDEYSHYLRKSSLGKWLQNEGIPAVYGVDTRSLTKHLR 152
Query: 149 EQGS-----------SPSTITVQGSF-----IPKPIKPET-DLVKIVSTKKPFFVKALSS 191
+ GS S TI+ S+ +P+ + P +LV VS +P +
Sbjct: 153 DAGSMLGRLSLEKSGSDRTISRSSSWRSAFDVPEWVDPNVQNLVSKVSINEPKLYVPPAD 212
Query: 192 VK----------TPFNVALIDCGVKENIIRCLVERGANVTVFPYDYPITSVANQFDGIFI 241
K + ID G+K N IRC ++RG + V P++Y T +DG+FI
Sbjct: 213 NKHIELQTGPDGKVLRILAIDVGMKYNQIRCFIKRGVELKVVPWNYDFTK--EDYDGLFI 270
Query: 242 SNGPGDPVQCMESTVPELKKLLETNTLQDLPIFGICLGHQLLALASGGKTIKLGYGNRAH 301
SNGPGDP ++ L +LE + P+FGICLGHQL+A A+G T+KL +GNR H
Sbjct: 271 SNGPGDP-SVLDDLSQRLSNVLEA---KKTPVFGICLGHQLIARAAGASTLKLKFGNRGH 326
Query: 302 NIPALDLTTGQCHITSQNHGYAVDVDTLPESGFKPFFQNLNDKSNEGMIHVSRPIFSTQF 361
NIP +G+C+ITSQNHG+AVDVDTL SG+KP F N ND SNEG+ H P FS QF
Sbjct: 327 NIPCTSTISGRCYITSQNHGFAVDVDTL-TSGWKPLFVNANDDSNEGIYHSELPYFSVQF 385
Query: 362 HPEAKGGPRDSAVLFDRYFDNMSQYR 387
HPE+ GPRD+ LFD + + +++
Sbjct: 386 HPESTPGPRDTEFLFDVFIQAVKEFK 411
>SPAC22G7.06c [R] KOG0370 Multifunctional pyrimidine synthesis protein CAD
(includes carbamoyl-phophate synthetase aspartate
transcarbamylase and glutamine amidotransferase)
Length = 2244
Score = 314 bits (804), Expect = 2e-85
Identities = 176/379 (46%), Positives = 235/379 (61%), Gaps = 35/379 (9%)
Query: 31 QGYSFGAPVSCSGEAVFTTSLVGYPESMTDPSYKGQILVFTQPLIGNYGVPSGEERDDFN 90
QGYSFGA S SGE VF T +VGYPES+TDPSY+GQILVFT P +GNYGVP D+ +
Sbjct: 70 QGYSFGADHSVSGELVFQTGMVGYPESLTDPSYRGQILVFTFPTVGNYGVPDRRILDEIS 129
Query: 91 -LLKYLESPHIHVRGIVVAEYAWRYSHWTAVESLATWCQRENVTAIGGIDTRAVVQILRE 149
L KY ES IHV I+++ Y+ YSH+ A SL W + + + I GIDTRA+ + +R+
Sbjct: 130 GLPKYFESNQIHVAAIIISSYSQNYSHFLAHSSLGEWLKEQGIPGIFGIDTRALTKKIRD 189
Query: 150 QGS--------------SPSTITVQG-----SFIPKPIK-PETD-LVKIVSTKKP--FFV 186
QGS +PS+IT G +F P K P T+ L VS K+P +
Sbjct: 190 QGSMLGRLLIQKDESPINPSSITGLGKDWSTAFEDIPWKNPNTENLTSQVSIKEPKLYEP 249
Query: 187 KALSSVKTP----FNVALIDCGVKENIIRCLVERGANVTVFPYDYPITSVANQFDGIFIS 242
+++K + +ID G+K N IRC + RG + V P+DY T +DG+FIS
Sbjct: 250 HPTTAIKKADGKIIRILVIDVGMKYNQIRCFLNRGVELLVVPWDYDFTK--ETYDGLFIS 307
Query: 243 NGPGDPVQCMESTVPELKKLLETNTLQDLPIFGICLGHQLLALASGGKTIKLGYGNRAHN 302
NGPGDP M+ V +K++LE+ T +P+FGIC GHQ++A A+G T K+ +GNR HN
Sbjct: 308 NGPGDP-SLMDLVVDRVKRVLESKT---VPVFGICFGHQIMARAAGASTTKMKFGNRGHN 363
Query: 303 IPALDLTTGQCHITSQNHGYAVDVDTLPESGFKPFFQNLNDKSNEGMIHVSRPIFSTQFH 362
IP + +G+C+ITSQNHGYAVD +L +G+K F N ND SNEG+ + P FS QFH
Sbjct: 364 IPCTCMISGRCYITSQNHGYAVDASSL-SNGWKELFVNANDGSNEGIYNTEYPFFSVQFH 422
Query: 363 PEAKGGPRDSAVLFDRYFD 381
PE+ GPRD+ LFD + D
Sbjct: 423 PESTPGPRDTEFLFDVFID 441
>CE03105 [R] KOG0370 Multifunctional pyrimidine synthesis protein CAD
(includes carbamoyl-phophate synthetase aspartate
transcarbamylase and glutamine amidotransferase)
Length = 2198
Score = 302 bits (773), Expect = 7e-82
Identities = 164/365 (44%), Positives = 223/365 (60%), Gaps = 18/365 (4%)
Query: 30 FQGYSFGAPVSCSGEAVFTTSLVGYPESMTDPSYKGQILVFTQPLIGNYGVPSGEERDDF 89
F G +GA S GE VF T +VGY ES+TDPSY Q+L T PLIGNYGVPS E D F
Sbjct: 13 FVGSIYGATKSVVGEIVFQTGMVGYVESLTDPSYAKQLLTLTYPLIGNYGVPSAEILDQF 72
Query: 90 NLLKYLESPHIHVRGIVVAEYA--WRYSHWTAVESLATWCQRENVTAIGGIDTRAVVQIL 147
L ES I ++V + +SHW AV+SL+ W ++ +V + GID R +V+ +
Sbjct: 73 KLPAEFESDRIWPAALIVEKICVDGEHSHWQAVQSLSEWLRKADVPCLSGIDVRQLVKKI 132
Query: 148 REQGSSPSTITVQG----SFIPKPIKPETDLVKIVSTKKPFFVKALSSVKTPFNVALIDC 203
RE G+ + + ++ +F + E +LV VS K+P + + +DC
Sbjct: 133 RETGTMKAKLVIESDNAQNFDYVDVNAE-NLVDFVSRKEPVVYGSGDQT-----ILAVDC 186
Query: 204 GVKENIIRCLVERGANVTVFPYDYPITSVANQFDGIFISNGPGDPVQCMESTVPELKKLL 263
G+K N IRCL +RG V V P+++PI + ++ +DG+F+SNGPGDP C P + +L
Sbjct: 187 GLKNNQIRCLAKRGFRVKVVPWNHPIDTESD-YDGLFLSNGPGDPEIC----APLVDRLA 241
Query: 264 ETNTLQDLPIFGICLGHQLLALASGGKTIKLGYGNRAHNIPALDLTTGQCHITSQNHGYA 323
+ D PIFGICLGHQ+L+ A G KT KL YGNR HN P TG+C+ITSQNHGYA
Sbjct: 242 KVIARGDKPIFGICLGHQILSRAIGAKTYKLKYGNRGHNQPCTHYATGRCYITSQNHGYA 301
Query: 324 VDVDTLPESGFKPFFQNLNDKSNEGMIHVSRPIFSTQFHPEAKGGPRDSAVLFDRYFDNM 383
VD D+LP + +K F N NDK+NEG++H S+P FS QFHPE GP D LFD + D++
Sbjct: 302 VDPDSLP-ADWKALFTNENDKTNEGIVHSSKPFFSVQFHPEHTAGPTDCEFLFDVFADSV 360
Query: 384 SQYRA 388
Q ++
Sbjct: 361 RQAKS 365
>Hs21361331 [R] KOG0370 Multifunctional pyrimidine synthesis protein CAD
(includes carbamoyl-phophate synthetase aspartate
transcarbamylase and glutamine amidotransferase)
Length = 1500
Score = 300 bits (768), Expect = 3e-81
Identities = 158/360 (43%), Positives = 228/360 (62%), Gaps = 11/360 (3%)
Query: 29 EFQGYSFGAPVSCSGEAVFTTSLVGYPESMTDPSYKGQILVFTQPLIGNYGVPSGEERDD 88
+ +GYSFG P S +GE VF T L GYPE++TDP+YKGQIL P+IGN G P D+
Sbjct: 55 KMKGYSFGHPSSVAGEVVFNTGLGGYPEAITDPAYKGQILTMANPIIGNGGAPDTTALDE 114
Query: 89 FNLLKYLESPHIHVRGIVVAEYAWRYSHWTAVESLATWCQRENVTAIGGIDTRAVVQILR 148
L KYLES I V G++V +Y+ Y+HW A +SL W Q E V AI G+DTR + +I+R
Sbjct: 115 LGLSKYLESNGIKVSGLLVLDYSKDYNHWLATKSLGQWLQEEKVPAIYGVDTRMLTKIIR 174
Query: 149 EQGSSPSTITVQGSFIPKPIKPETDLVKIVSTKKPFFVKALSSVKTPFNVALIDCGVKEN 208
++G+ I +G + + +L+ VSTK VK P V +DCG+K N
Sbjct: 175 DKGTMLGKIEFEGQPVDFVDPNKQNLIAEVSTKD---VKVYGK-GNPTKVVAVDCGIKNN 230
Query: 209 IIRCLVERGANVTVFPYDYPITSVANQFDGIFISNGPGDPVQCMESTVPELKKLLETNTL 268
+IR LV+RGA V + P+++ T + ++DGI I+ GPG+P E + ++K+LE++
Sbjct: 231 VIRLLVKRGAEVHLVPWNHDFTKM--EYDGILIAGGPGNPA-LAEPLIQNVRKILESDRK 287
Query: 269 QDLPIFGICLGHQLLALASGGKTIKLGYGNRAHNIPALDLTTGQCHITSQNHGYAVDVDT 328
+ P+FGI G+ + LA+G KT K+ NR N P L++T Q IT+QNHGYA+D +T
Sbjct: 288 E--PLFGISTGNLITGLAAGAKTYKMSMANRGQNQPVLNITNKQAFITAQNHGYALD-NT 344
Query: 329 LPESGFKPFFQNLNDKSNEGMIHVSRPIFSTQFHPEAKGGPRDSAVLFDRYFDNMSQYRA 388
LP +G+KP F N+ND++NEG++H S+P F+ QFHPE GP D+ LFD +F + + +A
Sbjct: 345 LP-AGWKPLFVNVNDQTNEGIMHESKPFFAVQFHPEVTPGPIDTEYLFDSFFSLIKKGKA 403
>HsM4503019 [R] KOG0370 Multifunctional pyrimidine synthesis protein CAD
(includes carbamoyl-phophate synthetase aspartate
transcarbamylase and glutamine amidotransferase)
Length = 1500
Score = 296 bits (759), Expect = 3e-80
Identities = 157/360 (43%), Positives = 227/360 (62%), Gaps = 11/360 (3%)
Query: 29 EFQGYSFGAPVSCSGEAVFTTSLVGYPESMTDPSYKGQILVFTQPLIGNYGVPSGEERDD 88
+ +GYSFG P S +GE VF T L GYPE++TDP+YKGQIL P+IGN G P D+
Sbjct: 55 KMKGYSFGHPSSVAGEVVFNTGLGGYPEAITDPAYKGQILTMANPIIGNGGAPDTTSLDE 114
Query: 89 FNLLKYLESPHIHVRGIVVAEYAWRYSHWTAVESLATWCQRENVTAIGGIDTRAVVQILR 148
L KYLES I V G++V +Y+ Y+HW A +SL W Q E V AI G+DTR + +I+R
Sbjct: 115 LGLSKYLESNGIKVSGLLVLDYSKDYNHWLATKSLGQWLQEEKVPAIYGVDTRMLTKIIR 174
Query: 149 EQGSSPSTITVQGSFIPKPIKPETDLVKIVSTKKPFFVKALSSVKTPFNVALIDCGVKEN 208
++G+ I +G + + +L+ VSTK VK P V +DCG+K N
Sbjct: 175 DKGTMLGKIEFEGQPVDFVDPNKQNLIAEVSTKD---VKVYGK-GNPTKVVAVDCGIKNN 230
Query: 209 IIRCLVERGANVTVFPYDYPITSVANQFDGIFISNGPGDPVQCMESTVPELKKLLETNTL 268
+IR LV+RGA V + P+++ T + ++DGI I+ GPG+P E + ++K+LE++
Sbjct: 231 VIRLLVKRGAEVHLVPWNHDFTKM--EYDGILIAGGPGNPA-LAEPLIQNVQKILESDRK 287
Query: 269 QDLPIFGICLGHQLLALASGGKTIKLGYGNRAHNIPALDLTTGQCHITSQNHGYAVDVDT 328
+ P+FGI G+ + LA+G KT K+ NR N P L++T Q IT+QNH YA+D +T
Sbjct: 288 E--PLFGISTGNLITGLAAGAKTYKMSMANRGQNQPVLNITNKQAFITAQNHCYALD-NT 344
Query: 329 LPESGFKPFFQNLNDKSNEGMIHVSRPIFSTQFHPEAKGGPRDSAVLFDRYFDNMSQYRA 388
LP +G+KP F N+ND++NEG++H S+P F+ QFHPE GP D+ LFD +F + + +A
Sbjct: 345 LP-AGWKPLFVNVNDQTNEGIMHESKPFFAVQFHPEVTPGPIDTEYLFDSFFSLIKKGKA 403
>7293258 [R] KOG0370 Multifunctional pyrimidine synthesis protein CAD
(includes carbamoyl-phophate synthetase aspartate
transcarbamylase and glutamine amidotransferase)
Length = 2189
Score = 283 bits (723), Expect = 4e-76
Identities = 162/372 (43%), Positives = 224/372 (59%), Gaps = 31/372 (8%)
Query: 32 GYSFG-------APVSCSGEAVFTTSLVGYPESMTDPSYKGQILVFTQPLIGNYGVPSGE 84
GYSFG + V GE VF T +VGY E++TD SY GQILV T PLIGNYGVP+ +
Sbjct: 18 GYSFGYVPSENESKVGFGGEVVFQTGMVGYTEALTDRSYSGQILVLTYPLIGNYGVPAPD 77
Query: 85 ERDDFNLLKYLE--SPHIHVRGIVVAEYAWRYSHWTAVESLATWCQRENVTAIGGIDTRA 142
E D+ L + E + +VV E A HW ++L W ++ V I IDTRA
Sbjct: 78 E-DEHGLPLHFEWMKGVVQATALVVGEVAEEAFHWRKWKTLPDWLKQHKVPGIQDIDTRA 136
Query: 143 VVQILREQGSSPSTITVQ---------GSFIPKPIKPETDLVKIVSTKKPFFVKALSSVK 193
+ + LREQGS I + SF+ ++ +L K S K+ V + K
Sbjct: 137 LTKKLREQGSMLGKIVYEKPPVEGLPKSSFVDPNVR---NLAKECSVKERQ-VYGNPNGK 192
Query: 194 TPFNVALIDCGVKENIIRCLVERGANVTVFPYDYPITSVANQFDGIFISNGPGDPVQCME 253
P +A++DCG+K N +RCL++RGA+VT+ P+ + QFD +F+SNGPG+P C +
Sbjct: 193 GP-RIAILDCGLKLNQLRCLLQRGASVTLLPWSARLED--EQFDALFLSNGPGNPESC-D 248
Query: 254 STVPELKKLLETNTLQDLPIFGICLGHQLLALASGGKTIKLGYGNRAHNIPALDLTTGQC 313
V +++K++E P+FGICLGHQLLA A G T K+ YGNR HN+P L TG+C
Sbjct: 249 QIVQQVRKVIEEG---QKPVFGICLGHQLLAKAIGCSTYKMKYGNRGHNLPCLHRATGRC 305
Query: 314 HITSQNHGYAVDVDTLPESGFKPFFQNLNDKSNEGMIHVSRPIFSTQFHPEAKGGPRDSA 373
+TSQNHGYAVD++ LP+ G+ F N ND +NEG++H S+P FS QFHPE GP+D+
Sbjct: 306 LMTSQNHGYAVDLEQLPD-GWSELFVNANDGTNEGIVHASKPYFSVQFHPEHHAGPQDTE 364
Query: 374 VLFDRYFDNMSQ 385
LFD + +++ Q
Sbjct: 365 FLFDVFMESIQQ 376
>At3g27740 [R] KOG0370 Multifunctional pyrimidine synthesis protein CAD
(includes carbamoyl-phophate synthetase aspartate
transcarbamylase and glutamine amidotransferase)
Length = 428
Score = 207 bits (526), Expect = 3e-53
Identities = 132/371 (35%), Positives = 187/371 (49%), Gaps = 36/371 (9%)
Query: 34 SFGAPVSCSGEAVFTTSLVGYPESMTDPSYKGQILVFTQPLIGNYGVPSGEERDDFNLLK 93
SFGAP + E VF TSL GY E +TDPSY GQ ++ T P IGN GV +E
Sbjct: 70 SFGAPGTRIAELVFNTSLTGYQEILTDPSYAGQFVLMTNPQIGNTGVNPDDE-------- 121
Query: 94 YLESPHIHVRGIVVAEYAWRYSHWTAVESLATWCQRENVTAIGGIDTRAVVQILREQGSS 153
ES + G+V+ + S+W ++LA + ++ + +DTRA+ + LRE GS
Sbjct: 122 --ESGQCFLTGLVIRNLSISTSNWRCTKTLADYLTERDIMGVYDLDTRAITRRLREDGSL 179
Query: 154 PSTITVQGSFIPKPIKPET--------DLVKIVSTKKPFFVKALSSVKTPFN-------- 197
++ + S + + DL+ VS K P+ ++ + FN
Sbjct: 180 IGVLSTEQSKTDDELLQMSRSWDIVGIDLISDVSCKSPYEWVDKTNAEWDFNTNSRDGKS 239
Query: 198 --VALIDCGVKENIIRCLVERGANVTVFPYDYPITSVANQF-DGIFISNGPGDPVQCMES 254
V D G+K+NI+R L G +TV P +P DGI SNGPGDP S
Sbjct: 240 YKVIAYDFGIKQNILRRLSSYGCQITVVPSTFPAAEALKMNPDGILFSNGPGDP-----S 294
Query: 255 TVPELKKLLETNTLQDLPIFGICLGHQLLALASGGKTIKLGYGNRAHNIPALDLTTGQCH 314
VP + ++ L +P++GIC+GHQLL A GGKT K+ +G+ N P + TGQ
Sbjct: 295 AVPYAVETVK-ELLGKVPVYGICMGHQLLGQALGGKTFKMKFGHHGGNHPVRNNRTGQVE 353
Query: 315 ITSQNHGYAVDVDTLPESGFKPFFQNLNDKSNEGMIHVSRPIFSTQFHPEAKGGPRDSAV 374
I++QNH YAVD +LP G + NLND S G+ + S Q+HPEA GP DS
Sbjct: 354 ISAQNHNYAVDPASLP-GGVEVTHVNLNDGSCAGLSFPEMNVMSLQYHPEASPGPHDSDN 412
Query: 375 LFDRYFDNMSQ 385
F + + M +
Sbjct: 413 AFREFIELMKR 423
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.318 0.136 0.407
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,236,002
Number of Sequences: 60738
Number of extensions: 1201776
Number of successful extensions: 2536
Number of sequences better than 1.0e-05: 10
Number of HSP's better than 0.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 2481
Number of HSP's gapped (non-prelim): 10
length of query: 409
length of database: 30,389,216
effective HSP length: 109
effective length of query: 300
effective length of database: 23,768,774
effective search space: 7130632200
effective search space used: 7130632200
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)