ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI6726 normal K KOG2261 Transcription Polycomb enhancer protein, EPC
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI6726 2340631 2338214 -806
(806 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YFL024c [K] KOG2261 Polycomb enhancer protein EPC 332 2e-90
SPCC830.05c [K] KOG2261 Polycomb enhancer protein EPC 162 1e-39
Hs21361489 [K] KOG2261 Polycomb enhancer protein EPC 72 4e-12
Hs13376810 [K] KOG2261 Polycomb enhancer protein EPC 71 6e-12
HsM14149710 [K] KOG2261 Polycomb enhancer protein EPC 58 7e-08
>YFL024c [K] KOG2261 Polycomb enhancer protein EPC
Length = 832
Score = 332 bits (850), Expect = 2e-90
Identities = 177/361 (49%), Positives = 244/361 (67%), Gaps = 15/361 (4%)
Query: 8 SSRFRHRKISVKQRLRIYKSHEIKDLEQEDVSAISSQHQQRELMXXXXXXXXXXXXXXXX 67
+SRFRHRKISVKQ L+IY +++K L+++++ QQRE++
Sbjct: 52 NSRFRHRKISVKQHLKIYLPNDLKHLDKDEL-------QQREVVEIETGVEKNEEKEVHL 104
Query: 68 XXILQSNQLRENKKDLFIPTPDASKTWDEFDRFYQGEFKCPTSYIQFSAQLEDCCGTLYN 127
ILQ KD +IPTPDAS TW+E+D+FY G F+ TSYI+FSA +EDCCGT YN
Sbjct: 105 HRILQMGSGHTKHKD-YIPTPDASMTWNEYDKFYTGSFQETTSYIKFSATVEDCCGTNYN 163
Query: 128 MDEEDEIFLAD-LNKSLADSVEPLTEDEFELIMANFESSIKDRQPFLSMDPESILSFADL 186
MDE DE FL + +NK +D LTEDEFE++ ++FE +I +RQPFLSMDPESILSF +L
Sbjct: 164 MDERDETFLNEQVNKGSSDI---LTEDEFEILCSSFEHAIHERQPFLSMDPESILSFEEL 220
Query: 187 KPTMLKNDVGDSGVKKELAKEIGMPEDEPFLTMFDNKRPLGKREKNMETLIELFGEKIHD 246
KPT++K+D+ D ++ +L EI + F+T FD + R + LIE FG KI+D
Sbjct: 221 KPTLIKSDMADFNLRNQLNHEINSHKTH-FITQFDPVSQMNTRP--LIQLIEKFGSKIYD 277
Query: 247 HWKQRKISRHGCDIFPQLKSERNNDKDDNDPYVCFRRRELRQPRKTRRIDVQNSQKLRLL 306
+W++RKI +G +IFPQLK ER +K++ DPYVCFRRRE+R PRKTRRID+ NSQ+LR L
Sbjct: 278 YWRERKIEVNGYEIFPQLKFERPGEKEEIDPYVCFRRREVRHPRKTRRIDILNSQRLRAL 337
Query: 307 CQQLEYTKDLALTVAKRERAVLEVLENEKFVFQARAQLKTMKRKLGIDADNEDLYSAKKQ 366
Q+L+ KDLAL VAKRE L + +E +F R ++K +KR L I +++DL + K++
Sbjct: 338 HQELKNAKDLALLVAKRENVSLNWINDELKIFDQRVKIKNLKRSLNISGEDDDLINHKRK 397
Query: 367 K 367
+
Sbjct: 398 R 398
Score = 303 bits (776), Expect = 7e-82
Identities = 148/279 (53%), Positives = 199/279 (71%), Gaps = 17/279 (6%)
Query: 484 YVKLPNSKIPDIVLEDVGKLLHSKEKSTRKFVEDRMRKRKQEDGDIFFNLTDDPYNPVFN 543
YVKLP+SKIPDIVLEDV LL+SKEK+ RKFV+++M KRK ED D+FFNLTDDP+NPVF+
Sbjct: 489 YVKLPSSKIPDIVLEDVDALLNSKEKNARKFVQEKMEKRKIEDADVFFNLTDDPFNPVFD 548
Query: 544 LSIPDNVSPQDAPFSSVAGSKFEVKTSYYSPNLQNYITGTANDIKVFNKEGEAVENNEY- 602
+S+P N S + PF+S+A SKF++ S+YS +L Y+ G ++DI++++ G + + Y
Sbjct: 549 MSLPKNFSTSNVPFASIASSKFQIDRSFYSSHLPEYLKGISDDIRIYDSNGRSRNKDNYN 608
Query: 603 ------KKLEFFNPFDNEIHTHSREFPIAFRRRRGRFNMEYIDQRKTDHNIND----MLL 652
KK E ++PF + HSRE+PI FR+R GR N++Y+D+ + L+
Sbjct: 609 LDTKRIKKTELYDPFQENLEIHSREYPIKFRKRVGRSNIKYVDRMPNFTTSSTKSACSLM 668
Query: 653 QFIDLDGIQKQEL------DNDVINVYDSKLDDLSRSYYHWKYDSNYNIYGSKFSDEPAK 706
F+D D I+K++ D D INVYDSK D+ R Y WKYDS N YG KFSDEPA+
Sbjct: 669 DFVDFDSIEKEQYSREGSNDTDSINVYDSKYDEFVRLYDKWKYDSPQNEYGIKFSDEPAR 728
Query: 707 LNQISNDTQVVRFGTMLGSKAYEQLRDATIKYRQEQINK 745
LNQISNDTQV+RFGTMLG+K+YEQLR+ATIKYR++ I +
Sbjct: 729 LNQISNDTQVIRFGTMLGTKSYEQLREATIKYRRDYITR 767
>SPCC830.05c [K] KOG2261 Polycomb enhancer protein EPC
Length = 557
Score = 162 bits (411), Expect = 1e-39
Identities = 112/370 (30%), Positives = 182/370 (48%), Gaps = 51/370 (13%)
Query: 1 MPAPAVDSSRFRHRKISVKQRLRIYKSHEIKDLEQEDVSAISSQHQQRELMXXXXXXXXX 60
M + + ++ +R RK+ +K + IY +I D ++E + Q+ +
Sbjct: 1 MSSVSKNARAYRQRKVGIKTVMPIYFERDIPDFDEE------ASLQRTVPLVESGVEKEE 54
Query: 61 XXXXXXXXXILQSNQ--LRENKKDLFIPTPDASKTWDEFDRFYQGEFKCPTSYIQFSAQL 118
I ++++ +R ++K L IPT +A K D++Y+ F P + I+FS +
Sbjct: 55 EEEKHLQQVINEAHEAIVRGSEKKLIIPTREA-KNIGIIDKYYKKNFILPKTLIRFSLTV 113
Query: 119 EDCCGTLYNMDEEDEIFLADLNKSLADSVEPLTEDEFELIMANFESSIKDRQPFLSMDPE 178
E+C Y MDE D + L K S+ +E +FE++M FE I QPFLSMD
Sbjct: 114 EECTNPEYCMDEHDTEYFLKL-KQAQPSLSKFSELDFEIVMQTFEEEINQNQPFLSMDTS 172
Query: 179 SILSFADLKPTMLKNDVGDSGVKKELAKEIGMPEDEPFLTMFDNKRPLGKREKNMETLIE 238
IL ++L +T F+ K L ++
Sbjct: 173 QILPLSEL------------------------------ITSFELKDVL---------YLK 193
Query: 239 LFGEKIHDHWKQRKISRHGCDIFPQLKSERNNDKDDNDPYVCFRRRELRQPRKTRRIDVQ 298
+++ +W++R+IS+ G I K++ +DKDD+DPYVCFRRRE+RQ RKTRR D Q
Sbjct: 194 PLASQVYPYWRERRISKGGLPIMA--KAQVGDDKDDDDPYVCFRRREIRQARKTRRSDAQ 251
Query: 299 NSQKLRLLCQQLEYTKDLALTVAKRERAVLEVLENEKFVFQARAQLKTMKRKLGIDADNE 358
+ +LR L Q +E + L V KRE+ L+ LE++ +FQ R +K +KR L I +E
Sbjct: 252 SYDRLRRLRQSMETSLQLLEQVYKREQKKLQALEDDYAIFQKRCLVKKLKRTLNIKDSDE 311
Query: 359 DLYSAKKQKL 368
L + K++ +
Sbjct: 312 LLINPKRRPI 321
>Hs21361489 [K] KOG2261 Polycomb enhancer protein EPC
Length = 763
Score = 71.6 bits (174), Expect = 4e-12
Identities = 65/269 (24%), Positives = 112/269 (41%), Gaps = 60/269 (22%)
Query: 77 RENKKDLFIPTPDASKTWDEFDRFYQGEFKCPTSYIQFSAQLEDCCGTLYNMDEEDEIFL 136
RE K+ + IP P+A + ++R Y+GEFK P +I +N+D E +
Sbjct: 22 REKKESMVIPVPEAESNVNYYNRLYKGEFKQPKQFIHIQP---------FNLDNEQPDYD 72
Query: 137 ADLNKSLADSVEPLTEDEFELIMANFESSIKDRQPFLSMDPESILSFADLKPTMLKNDVG 196
D +EDE L N + IK Q + +D L+
Sbjct: 73 MD------------SEDETLLNRLNRKMEIKPLQFEIMID-------------RLEKASS 107
Query: 197 DSGVKKELAKEIGMPEDEPFLTMFDNKRPLGKREKNMETLIELFGEKIHDHWKQRKISRH 256
+ V + AK + + ED+ + + ++D+W +++ +
Sbjct: 108 NQLVTLQEAKLL-LNEDDYLI------------------------KAVYDYWVRKRKNCR 142
Query: 257 GCDIFPQLKSERNNDKDDNDPYVCFRRR-ELRQPRKTRRIDVQNSQKLRLLCQQLEYTKD 315
G + PQ+K E+ + +NDPYV FRRR E Q RK R+ D + +K+ L ++
Sbjct: 143 GPSLIPQIKQEKRDGSTNNDPYVAFRRRTEKMQTRKNRKNDEASYEKMLKLRREFSRAIT 202
Query: 316 LALTVAKRERAVLEVLENEKFVFQARAQL 344
+ + +RE+ E+L V + R L
Sbjct: 203 ILEMIKRREKTKRELLHLTLEVVEKRYHL 231
>Hs13376810 [K] KOG2261 Polycomb enhancer protein EPC
Length = 836
Score = 71.2 bits (173), Expect = 6e-12
Identities = 62/268 (23%), Positives = 105/268 (39%), Gaps = 60/268 (22%)
Query: 78 ENKKDLFIPTPDASKTWDEFDRFYQGEFKCPTSYIQFSAQLEDCCGTLYNMDEEDEIFLA 137
E + ++ IP P+A ++ Y GEFK P I D Y++D EDE+F+
Sbjct: 67 EKRDNMVIPVPEAESNIAYYESIYPGEFKMPKQLIHIQPFSLDAEQPDYDLDSEDEVFVN 126
Query: 138 DLNKSLADSVEPLTEDEFELIMANFESSIKDRQPFLSMDPESILSFADLKPTMLKNDVGD 197
L K + ++ FE I DR L+ G
Sbjct: 127 KLKKKM------------DICPLQFEEMI-DR---------------------LEKGSGQ 152
Query: 198 SGVKKELAKEIGMPEDEPFLTMFDNKRPLGKREKNMETLIELFGEKIHDHWKQRKISRHG 257
V + AK + +DE +++++W +++ + G
Sbjct: 153 QPVSLQEAKLLLKEDDELI-------------------------REVYEYWIKKRKNCRG 187
Query: 258 CDIFPQLKSERNNDKDDNDPYVCFRRR-ELRQPRKTRRIDVQNSQKLRLLCQQLEYTKDL 316
+ P +K E+ + NDPYV FRRR E Q RK R+ D + +K+ L + L +
Sbjct: 188 PSLIPSVKQEKRDGSSTNDPYVAFRRRTEKMQTRKNRKNDEASYEKMLKLRRDLSRAVTI 247
Query: 317 ALTVAKRERAVLEVLENEKFVFQARAQL 344
+ +RE++ E+L + + R L
Sbjct: 248 LEMIKRREKSKRELLHLTLEIMEKRYNL 275
>HsM14149710 [K] KOG2261 Polycomb enhancer protein EPC
Length = 676
Score = 57.8 bits (138), Expect = 7e-08
Identities = 31/102 (30%), Positives = 55/102 (53%), Gaps = 1/102 (0%)
Query: 244 IHDHWKQRKISRHGCDIFPQLKSERNNDKDDNDPYVCFRRR-ELRQPRKTRRIDVQNSQK 302
++D+W +++ + G + PQ+K E+ + +NDPYV FRRR E Q RK R+ D + +K
Sbjct: 43 VYDYWVRKRKNCRGPSLIPQIKQEKRDGSTNNDPYVAFRRRTEKMQTRKNRKNDEASYEK 102
Query: 303 LRLLCQQLEYTKDLALTVAKRERAVLEVLENEKFVFQARAQL 344
+ L ++ + + +RE+ E+L V + R L
Sbjct: 103 MLKLRREFSRAITILEMIKRREKTKRELLHLTLEVVEKRYHL 144
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.315 0.133 0.377
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,459,966
Number of Sequences: 60738
Number of extensions: 1758389
Number of successful extensions: 5498
Number of sequences better than 1.0e-05: 5
Number of HSP's better than 0.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 5482
Number of HSP's gapped (non-prelim): 11
length of query: 806
length of database: 30,389,216
effective HSP length: 115
effective length of query: 691
effective length of database: 23,404,346
effective search space: 16172403086
effective search space used: 16172403086
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)