ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI6777 good R KOG1839 General function prediction only Uncharacterized protein CLU1/cluA/TIF31 involved in mitochondrial morphology/distribution, also found associated with eIF-3
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI6777 2360375 2356569 -1269
(1269 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YMR012w [R] KOG1839 Uncharacterized protein CLU1/cluA/TIF31 invo... 937 0.0
SPBC530.06c [R] KOG1839 Uncharacterized protein CLU1/cluA/TIF31 ... 214 7e-55
CE00213 [R] KOG1839 Uncharacterized protein CLU1/cluA/TIF31 invo... 193 1e-48
7302977 [R] KOG1839 Uncharacterized protein CLU1/cluA/TIF31 invo... 158 6e-38
Hs22062896 [R] KOG1839 Uncharacterized protein CLU1/cluA/TIF31 i... 157 1e-37
At3g52140 [R] KOG1839 Uncharacterized protein CLU1/cluA/TIF31 in... 117 1e-25
>YMR012w [R] KOG1839 Uncharacterized protein CLU1/cluA/TIF31 involved in
mitochondrial morphology/distribution also found
associated with eIF-3
Length = 1277
Score = 937 bits (2423), Expect = 0.0
Identities = 510/1283 (39%), Positives = 754/1283 (58%), Gaps = 82/1283 (6%)
Query: 4 DNIEVIVKGTPSYTKSKNSDIKYQLGKESNVSHLRTFLSFEESTKFYTSYDL--IENSRV 61
DN K SKN+DI +++GKES + + L+ S+K+ T+ L IE
Sbjct: 23 DNHSHNTKHLKKTQSSKNNDISFEIGKESKIQTVLDVLAMIPSSKYLTNVGLKTIEGDSQ 82
Query: 62 VDDEDVLGDLAGNGSSLTFQFKPKAYNLVTAVQHIVGLRETLGFSSELEDGISEFAISSG 121
+ DE + ++ G S L Q K Y+ A++H++ +R+ +GF+ E DG+SEFAIS+G
Sbjct: 83 LSDEMSIKEIVGEKSELKLQLILKPYSAREALKHVITVRDFIGFAQETSDGLSEFAISTG 142
Query: 122 SQFQDMSLEPNSEKSNGSETT--------------ISDQEKVKFLQTCNELLESTNTDFN 167
S F + L P E+S E ++D+EK+KF + +E+ S
Sbjct: 143 SSFSSLPLGPIKERSKQEEKDEKSDPEEKKNTFKDVTDEEKLKFNEMVHEVFSSFKNSSI 202
Query: 168 IASLKTGNLLVTPVLKSLHFSAYNPVPAFYKNKGHLLYLQASTLENETFHITTSISGFYV 227
L + + ++TP ++SL F+ YNPVP FY++KGHL YLQ TLE E+F+IT SGFYV
Sbjct: 203 NKLLTSESNIITPCVRSLSFAPYNPVPPFYRSKGHLFYLQIVTLEGESFYITAIPSGFYV 262
Query: 228 NKSSSVKFDPSPKDEFEPK-------FNLIDLLTQVSKKFHQHVTSLRNKLSSTDSAQYV 280
NKS+S KFDPSPK+ + ++L DL+ SKKF HV + KLS+ DS YV
Sbjct: 263 NKSNSTKFDPSPKENTDENAHSSLIYYSLFDLIASRSKKFISHVQAFEKKLSALDSTSYV 322
Query: 281 KPASCFLSKPWLVSQLPSNNGDFMRTQLEHFNNDDERNFCDEFQAIKDLEINSSYDRLKN 340
+P++ FL KPW VS LP NN D++R Q + ERNF DEFQAIKDL ++ DR++
Sbjct: 323 RPSNTFLHKPWFVSSLPPNNPDYLRLQTAALDTTPERNFNDEFQAIKDLTTSTLQDRIEM 382
Query: 341 EKITAGLIHEFNSEAVKGAMAIFNNELTPIDPGTTGENAVYFHKSLIFSFVADVSGTYSS 400
E++ + ++HEF+ A GAM+IF ++ ++P + + ++ ++ +S+V+DVSG Y
Sbjct: 383 ERLFSKVVHEFSVTAASGAMSIFYSDFVAMNPESPTRDQIFLKDNIFYSYVSDVSGNYEG 442
Query: 401 IGGNEAAYAVANQDLQIINSLNRLGLKGIRHCLTAIIDYAGHRLLVQSPVPGLLTPVGVN 460
GG+EAA A +NQDL+ IN LNRL + +R+ LT ++++AG R+L Q+PVPGLL +G
Sbjct: 443 KGGDEAAIAASNQDLKTINILNRLHMHEVRYLLTTVVEFAGRRILAQTPVPGLLATMGNK 502
Query: 461 IIVDEED-KEVAEPMETLISVNYGYDDFVATLKFDEKFHEKVCE--FSKNFYLKEHKVEE 517
I+ D +EV E I+V YG D+ + + +D F + V E F K F+LK+HKV
Sbjct: 503 IVKDANTGEEVTEDFVNDINVKYGLDEGLGKIVYDADF-DSVLEKKFVKAFHLKKHKVNG 561
Query: 518 VDLRISSKSKGIFGVDQRAYILDLANTNPVDIEFVKAHYDDVKE--NKYPHRQXXXXXXX 575
+L SS+SKGI G D+R YILDLANT P+DI F + ++D+++E N+YPHRQ
Sbjct: 562 TELAFSSQSKGIVGFDKRRYILDLANTYPLDINFARQNFDNIEETGNRYPHRQTLLRPEL 621
Query: 576 XXXWRAEKIAASGKTLQEASEDVSFIYNPDAYVIDGVEDENVADMSKFLNDTVLTLFLED 635
W K+ G ++A E+ F YNPDAY ++G+ED NV +MS +L V+ ++D
Sbjct: 622 VEKWWNNKVEKEGVEFEKAYEENLFSYNPDAYQVEGIEDANVDEMSNYLQKEVIPSVIQD 681
Query: 636 ILKGNSNIPYDGQHLTDLFHTNGVNMRYLGKAIEFVKAKYEDQKQERAKYLSKIEQENKE 695
L GN + PY+G+HL D H NG+NMRYLGK IE + + + Q + L +EQ+NKE
Sbjct: 682 YLSGNLSTPYNGEHLADTLHKNGINMRYLGKIIELSQKELDSQIVHYEQNLKAVEQDNKE 741
Query: 696 YQDWETGYLVKVEKLIKERQEEINKYVQQGKEVPSKLKEQIQLDKADLKEPVRNEGCTVE 755
Y+DWE YL K+E +IKERQ +INK VQ+GKEVP +L E ++L+ ++K+P + V
Sbjct: 742 YEDWEKSYLQKIENMIKERQAKINKLVQEGKEVPKELTEDLKLNDEEIKKPTDGKPVVVA 801
Query: 756 VDQFEGLIAVCELEMIARSIKHIFRQQSKKLSSPTLVPHLVAFFLNLLFGKSYNESVTVE 815
D+ LI + ELE+++RS+KH+ + SK + LVP LVA+ N+L G +YN E
Sbjct: 802 YDELVPLIKISELEIVSRSLKHVLKDLSKDV-PVFLVPSLVAYVFNMLVGINYNADPKPE 860
Query: 816 NLDALFDINELEFAQYTREQLIEEVRVQAKLRFRYDLTSEWFDINEKRFSKYALIRAIAQ 875
+D + +N+ FA+ TR +L+E V QA LRFR+ L S W + + + + LIR+++
Sbjct: 861 PVDEFYPVNKCSFAKLTRSELLEAVSKQAFLRFRHQLPSNWIEAYME--NPFTLIRSVSY 918
Query: 876 KFGIQLINKEYFFTKEQYEKWKQAQDKKLRSKIVDPKQTFSINDFSLRPVIKGAEFQSLI 935
KFGIQL+NKEYFFT+EQ E +KQ+ DKK+R+K V+P TFS++D ++ P +K +E+ S +
Sbjct: 919 KFGIQLLNKEYFFTREQLESYKQSLDKKIRNKFVEPPTTFSLSDLTIIPRVKFSEYTSSV 978
Query: 936 AEELWIQGASLVNAVSVXXXXXXXXXXXXXXXXXXXXXXXXXXXTSXXXXXXXXXXXXMN 995
+EE W QGAS++N
Sbjct: 979 SEEFWAQGASMIN-------------------------------------------EDKQ 995
Query: 996 EALTLLGQSIAFREDIFGLVHPSLVSSYLLLSNMYSRLGQYSQAVTFCNKAALLSERCYG 1055
ALTLL QSI ED+ ++HP++ YL LS +Y++L Y +A+ FC KA + ER G
Sbjct: 996 SALTLLAQSITVLEDVNNILHPAVAEKYLSLSAIYNKLALYPEAIAFCRKACTIYERVSG 1055
Query: 1056 VDSFETVRILSNLAYLEYGQGSIYNS--AXXXXXXXXXXXXXAPFVHSGRVNVFNLLFQI 1113
+DSFE +R L+NLA LE+ S YN+ H ++FN L Q+
Sbjct: 1056 IDSFEMMRALTNLAILEFSNESPYNATVVYNRLAEILKVYELPKIHHPAPTSIFNHLEQL 1115
Query: 1114 AASTEDKKVQIKILNKLSELLLKITGSEETLPYGQNESRIANLYTSLDDMSHALSHIEKA 1173
A +D K+ I++L +LS ++++ G +++L YG ESR+ NL+ +L D AL HI
Sbjct: 1116 ALGVQDTKLAIEVLGQLSSYVVELEG-KDSLAYGYTESRLGNLFAALKDFHRALEHITVT 1174
Query: 1174 KSIFSKELGLNDQTTLTSKQWSETIKGIITKQQQEKKLASAQQATKPANIX----XXXXX 1229
+ IF+K+LG+N + S+QW + +I +Q+K+LA Q +T +N
Sbjct: 1175 QGIFTKQLGMNHTHSAQSRQWVNGLSSLIMDLKQKKQLAQDQMSTTGSNSAGHKKTNHRQ 1234
Query: 1230 XXXXXXPALTNKSVDELLQFIEG 1252
P L NKSVDELL FIEG
Sbjct: 1235 KKDDVKPELANKSVDELLTFIEG 1257
>SPBC530.06c [R] KOG1839 Uncharacterized protein CLU1/cluA/TIF31 involved in
mitochondrial morphology/distribution also found
associated with eIF-3
Length = 1174
Score = 214 bits (545), Expect = 7e-55
Identities = 149/553 (26%), Positives = 257/553 (45%), Gaps = 79/553 (14%)
Query: 183 KSLHFSAYNPVPAFYKNKGHLLYLQASTLENETFHITTSISGFYVNKSSSVKFDPSPKDE 242
+SL S +NPVPA + +GHLLYL T+E +T++IT+ +SGFYVN +S KFDPSP D+
Sbjct: 204 RSLALSGWNPVPAEFVIQGHLLYLTVLTIEGKTYNITSHVSGFYVNNCTSTKFDPSPCDD 263
Query: 243 FEPKFNLIDLLTQVSKKFHQHVTSLRNKLSSTDSAQYVKPASCFLSKPWLVSQLPSNNGD 302
+ +L+ LL Q+S F + + N S D+ PW+ +P + D
Sbjct: 264 LQ-SHSLVLLLEQLSPLFKERLHLSLNDYKSGDAIAQASITGTLPQAPWITFPVP-HRAD 321
Query: 303 FMRTQLEHF-----NNDDERNFCDEFQAIKDLEINSSYDRLKNEKITAGLIHEFNSEAVK 357
RTQ N + R++ +E Q+ ++++ DR+ E++T + +F AV+
Sbjct: 322 LSRTQKSELFPYIENQGNLRDWNEEIQSTREMDHEDVQDRVLRERLTVKTLQDFTDMAVE 381
Query: 358 GAMAIFNNELTPIDPGTTGENAVYFHKSLIFSFVADVSGTYSSIGGNEAAYAVANQDLQI 417
GA+ + N + ++P + ++ H ++ FS+ D G +S+ GG+ AAY+ +D+
Sbjct: 382 GAIDMVNGNIPSLNPLEPTASQMFVHNNIFFSYGRDSVGIFSTKGGDSAAYSAVGKDILA 441
Query: 418 INSLNRLGLKGIRHCLTAIIDYAGHRLLVQSPVPGLLTPVGVNIIVDEEDKEVAEPMETL 477
I LN+ L T ++DYAGHR++ Q+ VPG+ K++ L
Sbjct: 442 IRLLNQFDLSNPSLLGTCVVDYAGHRVVAQTIVPGIF-------------KQLENGSSHL 488
Query: 478 ISVNYGYDDFVATLKFDEKFHEKVCEFSKNFYLKEH-----KVEEVDLRISSKSKGIFGV 532
I YG + + +FDE F ++ S ++K+H K + L S +K + G
Sbjct: 489 I---YGKVEGESDFRFDESFEGELSRISDLLHIKKHFFVDGKEKSFPLYTSMDAKALKGS 545
Query: 533 DQRAYILDLANTNPVDIEFVKAHYDDVKEN--KYPHRQXXXXXXXXXXWRAEKI------ 584
D R Y++DL + P+D +F++ D+ E YPH+ + K+
Sbjct: 546 DGRTYLMDLYSLFPLDAQFLEVISDEKNEEFPAYPHKLVHVRPELVQLFYEMKLQAFVNA 605
Query: 585 ----AASGKTLQEASEDVSFI----------------------------YNPDAYVIDGV 612
A K L ++ + V +NPD + D +
Sbjct: 606 NHNDAPKKKNLNDSLKSVELEGNGIKLSSEKGKNNVNKVRNDNARFDCGFNPDCFRSDYI 665
Query: 613 -----------EDENVADMSKFLNDTVLTLFLEDILKGNSNIPYDGQHLTDLFHTNGVNM 661
+ EN +S++L+ V+ F++ + + +S +P DG L H +G+N+
Sbjct: 666 FPPDNKELYDKDIENSYALSQYLHAEVIPNFVKSLSEPSSFLPIDGVALCRAMHRSGINI 725
Query: 662 RYLGKAIEFVKAK 674
RYLG+ + K
Sbjct: 726 RYLGEIANIILQK 738
Score = 68.6 bits (166), Expect = 6e-11
Identities = 52/211 (24%), Positives = 88/211 (41%), Gaps = 2/211 (0%)
Query: 1000 LLGQSIAFREDIFGLVHPSLVSSYLLLSNMYSRLGQYSQAVTFCNKAALLSERCYGVDSF 1059
LL +S++ E I+G++H + +Y L+ +Y +L + +AV KA ++ ER G DS
Sbjct: 965 LLNESLSLHEQIYGVLHTEVARAYCQLAMIYHQLEKKEEAVELARKAVIVCERFLGFDSS 1024
Query: 1060 ETVRILSNLAYLEYGQGSIYNSAXXXXXXXXXXXXXAPFVHSGRVNVFNLLFQIAASTED 1119
ET NL+ E+ Q + + H +N F L + +E
Sbjct: 1025 ETSLAYMNLSLYEFSQKNEMQAVMHMQHALKLWYLVFGPDHPNTINSFTNLSLMLHGSEK 1084
Query: 1120 KKVQIKILNKLSELLLKITGSEETLPYGQNESRIANLYTSLDDMSHALSHIEKAKSIFSK 1179
K L +L KI G +T P ++A L D AL + A I +
Sbjct: 1085 FIQSQKCLQIAVDLSDKIFG--KTTPTASLYLQLAQLMVLNKDSRSALHAVRVAYDILKE 1142
Query: 1180 ELGLNDQTTLTSKQWSETIKGIITKQQQEKK 1210
LG + Q T ++ W + Q+++ +
Sbjct: 1143 TLGPDHQNTKEAEHWLSEFTALAVNQERQSR 1173
>CE00213 [R] KOG1839 Uncharacterized protein CLU1/cluA/TIF31 involved in
mitochondrial morphology/distribution also found
associated with eIF-3
Length = 1247
Score = 193 bits (491), Expect = 1e-48
Identities = 273/1248 (21%), Positives = 497/1248 (38%), Gaps = 193/1248 (15%)
Query: 34 VSHLRTFLSFEESTKFYTSYDLIENSRVVDDEDVLGDLAGNGSSLTFQFKPKAYNLVTAV 93
V L L E+T T + L N VD+ + + G T + Y + A
Sbjct: 72 VQELYQTLLDREATCHRTCFSLYLNGTAVDNYSEVRAIPGFVDGCTLNVVDEPYTIRDAR 131
Query: 94 QHIVGLRETLGFSSELEDGISEFAISSGSQFQDMSLEPNSEKSNGSETTISDQEKVKFLQ 153
H+ +RE L F G++E D P + + TTI+ Q + K
Sbjct: 132 LHLRQVRELLKF------GLTE----------DQHEPPCTNDAQSYLTTINLQPEEKKEP 175
Query: 154 TCNELLESTNTDFNIASLKTGNLLVTP-----VLKSLHFSAYNPVPAFYKNKGHLLYLQA 208
+++L + +LLV LK + FS YNP P K +G +LY+
Sbjct: 176 KPSDILPPDHALPGCKERSLAHLLVPQPKELIALKDIAFSPYNPPPGPRKLRGDVLYIDI 235
Query: 209 STLENETFHITTSISGFYVNKSSSVKFDPSPKDEFEPKF-NLIDLLTQVS---KKFHQHV 264
+T+EN +H+T GFYVN S +FDP+ + + + ++I+LL VS KK + +
Sbjct: 236 TTVENRIYHVTCCTRGFYVNNSQDGRFDPTVSNSNKTVYQSVIELLQNVSPGFKKVYPQI 295
Query: 265 TSLRNKLSSTDSAQYVKPASCFLSKPWLVSQLPSNN------GDFMRTQLEHFNNDDERN 318
R + + + P S ++ P S++ + R E R+
Sbjct: 296 LKRRQEKTLVERLPTSYPVSSWVGNPLKTDGYMSDSLRAIELTEPFRVGFEDHMPGLLRD 355
Query: 319 FCDEFQAIKDLEINSSYDRLKNEKITAGLIHEFNSEAVKGAMAIFNNELTPIDPGTTGEN 378
+ +E Q ++ S +R+ ++ + ++ + A +G +I + + I+PG +
Sbjct: 356 WNEELQTTFEMTRKSISERVIRDRSYYKIHADYVNAAARGVQSILDGNILAINPGEDKKT 415
Query: 379 AVYFHKSLIFSFVADVSGTYSSIGGNEAAYAVANQDLQIINSLNRLGLKGIRHCLTAIID 438
+Y ++ FS DV Y +GG+ AA+A + DLQ + + L + AI D
Sbjct: 416 HMYIWNNIFFSLGFDVRDHYKELGGDAAAFAATSTDLQGVRAFATLDDPKLNTLGMAIFD 475
Query: 439 YAGHRLLVQSPVPGLLTPVGVNIIVDEEDKEVAEPMETLISVNYGYDDFVATLKFDEKFH 498
Y G+R+ QS +PG+L E ++E SV YG DF T+ DEK+H
Sbjct: 476 YRGYRVTAQSIIPGIL----------EREQEQ--------SVVYGSIDFGKTVVSDEKYH 517
Query: 499 EKVCEFSKNFYLKEHKV--------EEVDLRISSKSKGIFGVDQRAYILDLANTNPVDIE 550
E + + + + H V EE+ L S ++KGI G D R Y+LDL + P D+
Sbjct: 518 ELLEDAAHKLKMLPHTVISEKDGVKEELKLYTSYEAKGIIGNDGRKYVLDLLRSMPPDVH 577
Query: 551 FVKAHYDDVK----------ENKYPHRQXXXXXXXXXXWRAEKIAASGKTLQEA---SED 597
++ DD + K+PH K++A + L +A S
Sbjct: 578 YL----DDAEVSEAAKTLGYPRKFPH----------------KLSALRRELIDAFCESRL 617
Query: 598 VSFIYNPDAYVIDGVEDENVADMSKFLNDTVLTLFLEDILKGNSNIPYDGQHLTDLFHTN 657
V+FI + D + + SK ND L + S + + N
Sbjct: 618 VTFIQLTAKKIRDLITE------SKEKNDETLIKQAAEAETELSLLFMAISEDKEFEAKN 671
Query: 658 GVNMRYLGKAIEFVKAKYEDQKQERAKYLSKIEQE--NKEYQDWETGYLVKVEKLIKERQ 715
V + +A V + YED +Y+ K + + + T L + +++ +
Sbjct: 672 KVVQDAIKEACAVVHSIYED------RYVMKFNPDCFSSNVKHAPTENLERQRRVVVDAA 725
Query: 716 EEINKYVQQGKEVPSKLKEQI--QLDKADLKEPVRNEGCTVEV-----DQFEGLIAVCE- 767
+ + Q+ E+ LK+ + +D +L + + G + + E ++
Sbjct: 726 DFL--LTQKIPELVQNLKDCVVQPIDGDNLADIMHINGINIRYLGEIGKRLENSVSFARP 783
Query: 768 ---LEMIARSIKHIFRQQSKKLSSPTLVPHLVAFFLNLLFGKSYNESVTVENLDALFDIN 824
+++ARS KH+ R+ + ++++ L + LN LF + S N+ +
Sbjct: 784 LVLSDIVARSAKHVIRKINVQITADQLSAS-TSHILNCLFSVVLDPSPIAANVAKKANKK 842
Query: 825 E------LEFAQYTREQLIEEVRVQAKLRFRYDLTSEWFD--INEKRFSKYALIRAIAQK 876
++ T L +R + + Y + ++ + K AL R I +
Sbjct: 843 NGKKRVTSAWSSLTTSALWNSIREDSASYYGYPIEADSLEKFTELHDIQKTALFRRICKV 902
Query: 877 FGIQLINKEYFFTKEQYEKWKQAQDKKLRSKIVDPKQTFSINDFSLRPVIKGAEFQSLIA 936
G+QL+ ++Y + + KK + D IN F P+IK E + A
Sbjct: 903 MGVQLVARDY--------QLDNSTAKKTSIFVEDD----IINFF---PIIKHHEPFTADA 947
Query: 937 EELWIQGASLVNAVSVXXXXXXXXXXXXXXXXXXXXXXXXXXXTSXXXXXXXXXXXXMNE 996
++++I+G A+S+ E
Sbjct: 948 KKMFIRGQ---QAMSIGAS---------------------------------------RE 965
Query: 997 ALTLLGQSIAFREDIFGLVHPSLVSSYLLLSNMYSRLGQYSQAVTFCNKAALLSERCYGV 1056
A +G+S+ ++G++HP + L+ + LG+ A+ +KAA++SER G+
Sbjct: 966 AYECIGESLNLMTLVYGVMHPDMPQCLRALARLSHVLGETGDALNNQHKAAVMSERLIGL 1025
Query: 1057 DSFETVRILSNLAYLEYG----QGSIYNSAXXXXXXXXXXXXXAPFVHSGRVNVFNLLFQ 1112
D+ T+ NLA+ +G GS+ P + N+ +LF
Sbjct: 1026 DAGNTIIEYINLAHFAFGALLIPGSLRPLYRARYLMNLVFGEKHPVMAQIDANIGLILFT 1085
Query: 1113 IAASTEDKKVQIKILNKLSELLLKITGSEETLPYGQNESRIANLYTSLDDMSHALSHIEK 1172
+ ++ +K L ++ + K G L G + IA + + D AL ++
Sbjct: 1086 V----QEFDTALKYLQS-ADAITKTIGEPRKLKTGLISNLIARTHAARGDFRAALVAEKE 1140
Query: 1173 AKSIFSKELGLNDQTTLTSKQWSETI-KGIITKQQQEKKLASAQQATK 1219
+I+S+ G N S ++ T+ + +T Q++ KL ++ T+
Sbjct: 1141 TFAIYSELYGPNHPRVNESSEYLRTLTQQAVTFQKKMLKLDNSTNITE 1188
>7302977 [R] KOG1839 Uncharacterized protein CLU1/cluA/TIF31 involved in
mitochondrial morphology/distribution also found
associated with eIF-3
Length = 1448
Score = 158 bits (399), Expect = 6e-38
Identities = 110/384 (28%), Positives = 186/384 (47%), Gaps = 32/384 (8%)
Query: 182 LKSLHFSAYNPVPAFYKNKGHLLYLQASTLENETFHITTSISGFYVNKSSSVKFDPSPKD 241
LK L SA+NP P K G L+YL T+E++ FHI+ GF++N+S+ F+P P +
Sbjct: 304 LKVLTTSAWNPPPGPRKLHGDLMYLYVVTMEDKRFHISACSKGFFINQSTDDTFNPKPDN 363
Query: 242 EFEPKFNLIDLLTQVSKKFHQHVTSLRNKLSSTDSAQYVKPASCFLSKPWL-------VS 294
+LIDLL+ +S F + +++ + + + + V A+ + W V
Sbjct: 364 PSHLSHSLIDLLSHISPSFRRAFQTIQKRRTMRHAFERV--ATPYQVYQWAAPILEHTVD 421
Query: 295 QLPSNNGDFMRTQLEHFNNDDERNFCDEFQAIKDLEINSSYDRLKNEKITAGLIHEFNSE 354
+ + + + E R++ +E Q ++L + +RL E+ + +F +
Sbjct: 422 AIRAEDAFSSKLGYEEHIPGQTRDWNEELQTTRELPRKTLPERLLRERAIFKVHGDFVTA 481
Query: 355 AVKGAMAIFNNELTPIDPGTTGENAVYFHKSLIFSFVADVSGTYSSIGGNEAAYAVANQD 414
A +GAMA+ + + I+PG + ++ ++ FS DV Y +GG+ AA+ D
Sbjct: 482 ATRGAMAVIDGNVLAINPGEDTKMQMFIWNNIFFSMGFDVRDHYKELGGDAAAFVAPRYD 541
Query: 415 LQIINSLNRLGLKGIRHCLTAIIDYAGHRLLVQSPVPGLLTPVGVNIIVDEEDKEVAEPM 474
L + N + ++G+ T ++DY G+R+ QS +PG+L E ++E
Sbjct: 542 LHGVRVYNAVDIEGLYTLGTVVVDYRGYRVTAQSIIPGIL----------EREQEQ---- 587
Query: 475 ETLISVNYGYDDFVATLKFDEKFHEKVCEFSKNFYLKEHKV-----EEVDLRISSKSKGI 529
SV YG DF T+ K+ E + + K+ + H V E V+L S + KGI
Sbjct: 588 ----SVVYGSIDFGKTVLSHPKYLELLRQAGKHLKILPHVVLNERDEPVELCSSVECKGI 643
Query: 530 FGVDQRAYILDLANTNPVDIEFVK 553
G D R YILDL T P D+ F+K
Sbjct: 644 IGNDGRHYILDLLRTFPPDVNFLK 667
>Hs22062896 [R] KOG1839 Uncharacterized protein CLU1/cluA/TIF31 involved in
mitochondrial morphology/distribution also found
associated with eIF-3
Length = 1131
Score = 157 bits (396), Expect = 1e-37
Identities = 113/392 (28%), Positives = 183/392 (45%), Gaps = 32/392 (8%)
Query: 182 LKSLHFSAYNPVPAFYKNKGHLLYLQASTLENETFHITTSISGFYVNKSSSVKFDPSPKD 241
LK L S +NP P K G L+YL T E+ IT S GFY+N+S++ F+P P
Sbjct: 37 LKVLTMSGWNPPPGNRKMHGDLMYLFVITAEDRQVSITASTRGFYLNQSTAYHFNPKPAS 96
Query: 242 EFEPKFNLIDLLTQVSKKFHQHVTSLRNKLSSTDSAQYVKPASCFLSKPWLVSQ------ 295
+L++LL Q+S F ++ L+ K + + A+ F W Q
Sbjct: 97 PRFLSHSLVELLNQISPTFKKNFAVLQKK--RVQRHPFERIATPFQVYSWTAPQAEHAMD 154
Query: 296 -LPSNNGDFMRTQLEHFNNDDERNFCDEFQAIKDLEINSSYDRLKNEKITAGLIHEFNSE 354
+ + + R E R++ +E Q ++L + +RL E+ + +F +
Sbjct: 155 CVRAEDAYTSRLGYEEHIPGQTRDWNEELQTTRELPRKNLPERLLRERAIFKVHSDFTAA 214
Query: 355 AVKGAMAIFNNELTPIDPGTTGENAVYFHKSLIFSFVADVSGTYSSIGGNEAAYAVANQD 414
A +GAMA+ + + I+P + ++ ++ FS DV Y GG+ AAY D
Sbjct: 215 ATRGAMAVIDGNVMAINPSEETKMQMFIWNNIFFSLGFDVRDHYKDFGGDVAAYVAPTND 274
Query: 415 LQIINSLNRLGLKGIRHCLTAIIDYAGHRLLVQSPVPGLLTPVGVNIIVDEEDKEVAEPM 474
L + + N + ++G+ T ++DY G+R+ QS +PG+L E D+E
Sbjct: 275 LNGVRTYNAVDVEGLYTLGTVVVDYRGYRVTAQSIIPGIL----------ERDQEQ---- 320
Query: 475 ETLISVNYGYDDFVATLKFDEKFHEKVCEFSKNFYLKEHKV-----EEVDLRISSKSKGI 529
SV YG DF T+ ++ E + S+ + H+V EEV+L S + KGI
Sbjct: 321 ----SVIYGSIDFGKTVVSHPRYLELLERTSRPLKILRHQVLNDRDEEVELCSSVECKGI 376
Query: 530 FGVDQRAYILDLANTNPVDIEFVKAHYDDVKE 561
G D R YILDL T P D+ F+ +++ E
Sbjct: 377 IGNDGRHYILDLLRTFPPDLNFLPVPGEELPE 408
>At3g52140 [R] KOG1839 Uncharacterized protein CLU1/cluA/TIF31 involved in
mitochondrial morphology/distribution also found
associated with eIF-3
Length = 1403
Score = 117 bits (293), Expect = 1e-25
Identities = 143/618 (23%), Positives = 239/618 (38%), Gaps = 130/618 (21%)
Query: 24 IKYQLGKESNVSHLRTFLSFEESTKFYTSYDLI------ENSRVVDDEDV--LGDLAGNG 75
++ QL +V +R FL T ++T Y+L+ E + D ++ + D+ G
Sbjct: 120 MELQLNPGDSVMDIRQFLLDAPETCYFTCYELLLRNKDGETHHLEDYNEISEVADITIGG 179
Query: 76 SSLTFQFKPKAYNLVTAVQHIVGLRETLGFSSELEDGISEFAISSGSQFQDMSLEPNSEK 135
SL + Y+ + H+ R+ L S+ + A+ D +L
Sbjct: 180 CSL--EMVAALYDDRSIRAHVHRARDLLSLSTLHSSLSTTLALQ-----YDAALNKVQNP 232
Query: 136 SNGSETTISDQEKVKFLQ----TCNELLESTNTDFNIASLKTGNLLVTPVLKSLHFSAYN 191
+ ++ + + E + F++ + +L+ ST+ + ++++ FS++N
Sbjct: 233 GDKPKSDVPELECLGFMEDVPGSLKKLINSTSEEIRS-------------VENIVFSSFN 279
Query: 192 PVPAFYKNKGHLLYLQASTLENETFHITTSISGFYVNKSSSVKFDPSPKDEFEPKFNLID 251
P P+ + G L+YL TLE + IT + FYVN SS DP P LI
Sbjct: 280 PPPSHRRLVGDLIYLDVVTLEGNKYCITGTTKTFYVNSSSGNILDPRPSKSGFEAATLIG 339
Query: 252 LLTQVSKKFHQHVTSLRNKLSSTDSAQYVKPASCFLSKPWL-VSQLPSNNGDFMR----- 305
LL ++S KF + + K +S + V+ S WL +P + D R
Sbjct: 340 LLQKLSSKFKKAFREVMEKKASAHPFENVQ--SLLPPHSWLRTYPVPDHKRDAARAEEAL 397
Query: 306 -----TQLEHFNND--DERNFCDEF------QAIKDLEINSSYDRLKNEKITAGLIHEFN 352
++L D +E C EF + L N R+ ++ + +F
Sbjct: 398 TISYGSELIGMQRDWNEELQSCREFPHTSPQERFVSLIENFLRCRILRDRALYKVSSDFV 457
Query: 353 SEAVKGAMAIFNNELTPIDPGTTGENAVYFHKSLIFSFVAD------------------- 393
A+ GA+ + + + PI+P +Y H ++ FSF D
Sbjct: 458 DAALNGAIGVISRCIPPINPTDPECLHMYVHNNIFFSFAVDADIEQLSKKRPSNQMTEKV 517
Query: 394 --------VSGTYSS-----------IGGNEAAYAVANQDLQIINSLNRLGLKGIRHCLT 434
GT + + +A YA AN DL+ + G+ +
Sbjct: 518 SSSEKVSCTEGTCDNEEHNNCNEAPLVENEQATYASANNDLKGTKLYQEADVPGLYNLAM 577
Query: 435 AIIDYAGHRLLVQ----------------SPVPGLLTPVGVNIIVDEEDKEVAEPMETLI 478
AIIDY GHR++ Q S +PG+L + DK A
Sbjct: 578 AIIDYRGHRVVAQVCSNTGTSKSLFLRLSSVLPGIL----------QGDKSDA------- 620
Query: 479 SVNYGYDDFVATLKFDEKFHEKVCEFSKNFYLKEHKVEEVD-----LRISSKSKGIFGVD 533
+ YG D + ++E FH KV E +K ++KEH V + L + KGI G D
Sbjct: 621 -LLYGSVDNGKKICWNEDFHAKVLEAAKLLHIKEHSVIDASETVFKLAAPVECKGIVGSD 679
Query: 534 QRAYILDLANTNPVDIEF 551
R Y+LDL P D +
Sbjct: 680 NRHYLLDLMRVTPRDANY 697
Score = 55.1 bits (131), Expect = 7e-07
Identities = 37/115 (32%), Positives = 60/115 (52%), Gaps = 17/115 (14%)
Query: 581 AEKIAASGKTLQEASEDVSFIYNPDAYV---IDG------VEDENVADMSKFLNDTVLTL 631
AE AA ++ + ++F NP+ + + G ++ENV +S +L D VL
Sbjct: 775 AEDYAAGSSESSKSCDQIAF--NPNVFTDFTLGGNQEEIAADEENVKKVSSYLVDVVLPK 832
Query: 632 FLEDILKGNSNIPYDGQHLTDLFHTNGVNMRYLGKAIEFVKAKYEDQKQERAKYL 686
F+ED+ + P DGQ LT+ H +GVN+RY+G+ I+ + DQ K+L
Sbjct: 833 FIEDLCTLEVS-PMDGQTLTEALHAHGVNVRYIGRVIDLL-----DQVANGVKHL 881
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.315 0.133 0.368
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 68,263,976
Number of Sequences: 60738
Number of extensions: 2906501
Number of successful extensions: 10074
Number of sequences better than 1.0e-05: 6
Number of HSP's better than 0.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 10010
Number of HSP's gapped (non-prelim): 28
length of query: 1269
length of database: 30,389,216
effective HSP length: 118
effective length of query: 1151
effective length of database: 23,222,132
effective search space: 26728673932
effective search space used: 26728673932
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.5 bits)