ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI6852 good FE KOG1448 Amino acid transport and metabolism Ribose-phosphate pyrophosphokinase
r_klactVI6852 good FE KOG1448 Nucleotide transport and metabolism Ribose-phosphate pyrophosphokinase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI6852 2388783 2387824 -320
(320 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YHL011c [FE] KOG1448 Ribose-phosphate pyrophosphokinase 578 e-165
SPCC1620.06c [FE] KOG1448 Ribose-phosphate pyrophosphokinase 417 e-117
YER099c [FE] KOG1448 Ribose-phosphate pyrophosphokinase 411 e-115
YBL068w [FE] KOG1448 Ribose-phosphate pyrophosphokinase 405 e-113
Hs4506129 [FE] KOG1448 Ribose-phosphate pyrophosphokinase 389 e-108
Hs4506127 [FE] KOG1448 Ribose-phosphate pyrophosphokinase 387 e-107
7294893 [FE] KOG1448 Ribose-phosphate pyrophosphokinase 383 e-106
Hs20539448 [FE] KOG1448 Ribose-phosphate pyrophosphokinase 374 e-103
CE27199 [FE] KOG1448 Ribose-phosphate pyrophosphokinase 371 e-103
CE00745 [FE] KOG1448 Ribose-phosphate pyrophosphokinase 371 e-103
7294894 [FE] KOG1448 Ribose-phosphate pyrophosphokinase 370 e-102
CE29454 [FE] KOG1448 Ribose-phosphate pyrophosphokinase 368 e-102
SPBC3D6.06c [FE] KOG1448 Ribose-phosphate pyrophosphokinase 266 2e-71
Hs4506133 [EF] KOG1503 Phosphoribosylpyrophosphate synthetase-as... 252 6e-67
Hs4506131 [EF] KOG1503 Phosphoribosylpyrophosphate synthetase-as... 252 6e-67
At1g32380 [FE] KOG1448 Ribose-phosphate pyrophosphokinase 232 6e-61
At2g35390 [FE] KOG1448 Ribose-phosphate pyrophosphokinase 231 1e-60
At2g44530 [FE] KOG1448 Ribose-phosphate pyrophosphokinase 226 3e-59
7301964 [EF] KOG1503 Phosphoribosylpyrophosphate synthetase-asso... 215 8e-56
CE03789 [EF] KOG1503 Phosphoribosylpyrophosphate synthetase-asso... 211 1e-54
YKL181w [FE] KOG1448 Ribose-phosphate pyrophosphokinase 200 3e-51
SPAC4A8.14 [FE] KOG1448 Ribose-phosphate pyrophosphokinase 200 3e-51
YOL061w [FE] KOG1448 Ribose-phosphate pyrophosphokinase 114 2e-25
Hs20542182 [FE] KOG1448 Ribose-phosphate pyrophosphokinase 68 2e-11
At2g42910 [FE] KOG1448 Ribose-phosphate pyrophosphokinase 60 3e-09
At1g10700 [FE] KOG1448 Ribose-phosphate pyrophosphokinase 60 6e-09
>YHL011c [FE] KOG1448 Ribose-phosphate pyrophosphokinase
Length = 320
Score = 578 bits (1489), Expect = e-165
Identities = 295/320 (92%), Positives = 311/320 (97%)
Query: 1 MATNSIKLLAPDVHRNLAELVAKRLGLKLTNCKLKRDPSGEVSFSIGESVRDQDIFIVTQ 60
M TNSIKLLAPDVHR LAELVAKRLGL+LT+ KLKRDP+GEVSFSIGESVRDQDIFI+TQ
Sbjct: 1 MPTNSIKLLAPDVHRGLAELVAKRLGLQLTSSKLKRDPTGEVSFSIGESVRDQDIFIITQ 60
Query: 61 IGSGDVNDRVLELLIMINASKTASARRITAIIPNFPYARQDRKDKSRAPITAKLMADMLT 120
IGSG VNDRVLELLIMINASKTASARRITAIIPNFPYARQDRKDKSRAPITAKLMADMLT
Sbjct: 61 IGSGVVNDRVLELLIMINASKTASARRITAIIPNFPYARQDRKDKSRAPITAKLMADMLT 120
Query: 121 TAGCDHVITMDLHASQIQGFFDVPVDNLYAEPSVVRYIKENVNFKEAIIISPDAGGAKRA 180
TAGCDHVITMDLHASQIQGFFDVPVDNLYAEPSVVRYIKENVN+ ++IIISPDAGGAKRA
Sbjct: 121 TAGCDHVITMDLHASQIQGFFDVPVDNLYAEPSVVRYIKENVNYMDSIIISPDAGGAKRA 180
Query: 181 AGLADRLDLNFALIHKERARANEVSRMVLVGDVSDKICIIVDDMADTCGTLAKAAEVLLE 240
A LADRLDLNFALIHKERARANEVSRMVLVGDV+DKICIIVDDMADTCGTLAKAAE+LLE
Sbjct: 181 ATLADRLDLNFALIHKERARANEVSRMVLVGDVTDKICIIVDDMADTCGTLAKAAEILLE 240
Query: 241 NKAKSVIAIVTHGILSGKAIENINHSKLDRVVCTNTVPFEEKMLRCPKLDAIDISSVLAE 300
N+AKSVIAIVTHG+LSG+AIENIN+SKLDRVVCTNTVPFEEK+ +CPKL IDISSVLAE
Sbjct: 241 NRAKSVIAIVTHGVLSGRAIENINNSKLDRVVCTNTVPFEEKIKKCPKLAVIDISSVLAE 300
Query: 301 AIRRLHNGESISYLFKNYPL 320
+IRRLHNGESISYLFKNYPL
Sbjct: 301 SIRRLHNGESISYLFKNYPL 320
>SPCC1620.06c [FE] KOG1448 Ribose-phosphate pyrophosphokinase
Length = 321
Score = 417 bits (1073), Expect = e-117
Identities = 214/321 (66%), Positives = 263/321 (81%), Gaps = 3/321 (0%)
Query: 1 MATNSIKLLAPDVHRNLAELVAKRLGLKLTNCKLKRDPSGEVSFSIGESVRDQDIFIVTQ 60
MA+NSIK+ A + H LAE VA+R+GL L + + + E S +IGESVRD+D+FI+ Q
Sbjct: 1 MASNSIKIFAGNSHPELAEKVARRIGLSLGKVAVVQYSNRETSVTIGESVRDEDVFIL-Q 59
Query: 61 IGSGDVNDRVLELLIMINASKTASARRITAIIPNFPYARQDRKDKSRAPITAKLMADMLT 120
G G +ND ++ELLIMINA ++ASARRITAIIP FPYARQD+KDKSRAPITA+L+A+ML
Sbjct: 60 TGCGSINDHLMELLIMINACRSASARRITAIIPCFPYARQDKKDKSRAPITARLVANMLQ 119
Query: 121 TAGCDHVITMDLHASQIQGFFDVPVDNLYAEPSVVRYIKENVN--FKEAIIISPDAGGAK 178
TAGC+H+ITMDLHASQIQGFF+VPVDNLYAEPSV+RYI+EN++ +I+SPDAGGAK
Sbjct: 120 TAGCNHIITMDLHASQIQGFFNVPVDNLYAEPSVLRYIRENIDTTVNPTVIVSPDAGGAK 179
Query: 179 RAAGLADRLDLNFALIHKERARANEVSRMVLVGDVSDKICIIVDDMADTCGTLAKAAEVL 238
RA LADRLDL+FALIHKER +ANEVSRMVLVGDV DK+ I+VDDMADTCGTL AA+ L
Sbjct: 180 RATALADRLDLDFALIHKERQKANEVSRMVLVGDVRDKLAILVDDMADTCGTLGLAAKTL 239
Query: 239 LENKAKSVIAIVTHGILSGKAIENINHSKLDRVVCTNTVPFEEKMLRCPKLDAIDISSVL 298
+N AK+V AIVTHGILSGKAI+ IN S L++V+ TNT+P ++K C K++ IDIS VL
Sbjct: 240 KDNGAKAVYAIVTHGILSGKAIKVINESALEKVIVTNTIPHDDKRSLCSKIETIDISGVL 299
Query: 299 AEAIRRLHNGESISYLFKNYP 319
AE IRR+H+GES+S LF P
Sbjct: 300 AECIRRIHHGESVSVLFSVAP 320
>YER099c [FE] KOG1448 Ribose-phosphate pyrophosphokinase
Length = 318
Score = 411 bits (1057), Expect = e-115
Identities = 205/321 (63%), Positives = 261/321 (80%), Gaps = 4/321 (1%)
Query: 1 MATNSIKLLAPDVHRNLAELVAKRLGLKLTNCKLKRDPSGEVSFSIGESVRDQDIFIV-T 59
M+TNSIKLLA + H LAEL+++RLG+ L+ + + + E S +IGES+RD+D++I+ T
Sbjct: 1 MSTNSIKLLAGNSHPGLAELISQRLGVPLSKVGVYQYSNKETSVTIGESIRDEDVYIIQT 60
Query: 60 QIGSGDVNDRVLELLIMINASKTASARRITAIIPNFPYARQDRKDKSRAPITAKLMADML 119
G ++ND ++ELLI+I+A KTAS RRITA+IPNFPYARQD+KDKSRAPITAKL+A++L
Sbjct: 61 GYGEHEINDFLMELLILIHACKTASVRRITAVIPNFPYARQDKKDKSRAPITAKLIANLL 120
Query: 120 TTAGCDHVITMDLHASQIQGFFDVPVDNLYAEPSVVRYIKENVNFKEAIIISPDAGGAKR 179
TAGCDHVITMDLHASQIQGFF +PVDNLY EPSV+ YI+ +F AI++SPDAGGAKR
Sbjct: 121 ETAGCDHVITMDLHASQIQGFFHIPVDNLYGEPSVLNYIRTKTDFNNAILVSPDAGGAKR 180
Query: 180 AAGLADRLDLNFALIHKERARANEVSRMVLVGDVSDKICIIVDDMADTCGTLAKAAEVLL 239
A LAD+LD+NFALIHKER +ANEVSRM+LVGDV+ K C+++DDMADTCGTL KA + L+
Sbjct: 181 VASLADKLDMNFALIHKERQKANEVSRMLLVGDVAGKSCLLIDDMADTCGTLVKACDTLM 240
Query: 240 ENKAKSVIAIVTHGILSGKAIENINHSKLDRVVCTNTVPFEEKMLRCPKLDAIDISSVLA 299
++ AK VIAIVTHGI SG A E + +S+L R+VCTNTVP + L +D +DIS +A
Sbjct: 241 DHGAKEVIAIVTHGIFSGSAREKLINSRLSRIVCTNTVPVD---LDLDIVDQVDISPTIA 297
Query: 300 EAIRRLHNGESISYLFKNYPL 320
EAIRRLHNGES+SYLF + P+
Sbjct: 298 EAIRRLHNGESVSYLFTHAPV 318
>YBL068w [FE] KOG1448 Ribose-phosphate pyrophosphokinase
Length = 355
Score = 405 bits (1040), Expect = e-113
Identities = 207/322 (64%), Positives = 260/322 (80%), Gaps = 5/322 (1%)
Query: 1 MATNSIKLLAPDVHRNLAELVAKRLGLKLTNCKLKRDPSGEVSFSIGESVRDQDIFIV-T 59
MA NSIKLLA + H +LAE ++K+LG+ L+ + + + E S +IGES+RD+D++I+ T
Sbjct: 37 MAINSIKLLAGNSHPDLAEQISKKLGIPLSKVGVYQYSNKETSVTIGESLRDEDVYIIQT 96
Query: 60 QIGSGDVNDRVLELLIMINASKTASARRITAIIPNFPYARQDRKDKSRAPITAKLMADML 119
IG ++ND ++ELLI+I+A + ASAR+IT +IPNFPYARQD+KDKSRAPITAKL+A++L
Sbjct: 97 GIGEQEINDFLMELLILIHACQIASARKITTVIPNFPYARQDKKDKSRAPITAKLVANLL 156
Query: 120 TTAGCDHVITMDLHASQIQGFFDVPVDNLYAEPSVVRYIK-ENVNFKEAIIISPDAGGAK 178
TAG DHVITMDLHASQIQGFF +PVDNLYAEPSV+ YI+ +F AI++SPDAGGAK
Sbjct: 157 QTAGADHVITMDLHASQIQGFFHIPVDNLYAEPSVLNYIRARKTDFDNAILVSPDAGGAK 216
Query: 179 RAAGLADRLDLNFALIHKERARANEVSRMVLVGDVSDKICIIVDDMADTCGTLAKAAEVL 238
R A LAD+LDLNFALIHKER +ANEVS+MVLVGDV++K C++VDDMADTCGTL KA + L
Sbjct: 217 RVAALADKLDLNFALIHKERQKANEVSKMVLVGDVTNKSCLLVDDMADTCGTLVKACDTL 276
Query: 239 LENKAKSVIAIVTHGILSGKAIENINHSKLDRVVCTNTVPFEEKMLRCPKLDAIDISSVL 298
+E+ AK VIAIVTHGI SG A E + +S+L R+VCTNTVP + L P D IDIS
Sbjct: 277 MEHGAKEVIAIVTHGIFSGSAREKLRNSRLSRIVCTNTVPVD---LDLPIADQIDISPTF 333
Query: 299 AEAIRRLHNGESISYLFKNYPL 320
AEAIRRLHNGES+SYLF + P+
Sbjct: 334 AEAIRRLHNGESVSYLFTHAPV 355
>Hs4506129 [FE] KOG1448 Ribose-phosphate pyrophosphokinase
Length = 318
Score = 389 bits (999), Expect = e-108
Identities = 195/317 (61%), Positives = 249/317 (78%), Gaps = 2/317 (0%)
Query: 5 SIKLLAPDVHRNLAELVAKRLGLKLTNCKLKRDPSGEVSFSIGESVRDQDIFIVTQIGSG 64
+I L + H++L++ VA RLGL+L K+ + E S IGESVR +D++I+ Q G G
Sbjct: 3 NIVLFSGSSHQDLSQRVADRLGLELGKVVTKKFSNQETSVEIGESVRGEDVYII-QSGCG 61
Query: 65 DVNDRVLELLIMINASKTASARRITAIIPNFPYARQDRKDKSRAPITAKLMADMLTTAGC 124
++ND ++ELLIMINA K AS+ R+TA+IP FPYARQD+KDKSRAPI+AKL+A+ML+ AG
Sbjct: 62 EINDNLMELLIMINACKIASSSRVTAVIPCFPYARQDKKDKSRAPISAKLVANMLSVAGA 121
Query: 125 DHVITMDLHASQIQGFFDVPVDNLYAEPSVVRYIKENV-NFKEAIIISPDAGGAKRAAGL 183
DH+ITMDLHASQIQGFFD+PVDNLYAEP+V+++I+EN+ +K II+SPDAGGAKR +
Sbjct: 122 DHIITMDLHASQIQGFFDIPVDNLYAEPAVLQWIRENIAEWKNCIIVSPDAGGAKRVTSI 181
Query: 184 ADRLDLNFALIHKERARANEVSRMVLVGDVSDKICIIVDDMADTCGTLAKAAEVLLENKA 243
ADRL++ FALIHKER +ANEV RMVLVGDV D++ I+VDDMADTCGT+ AA+ LL A
Sbjct: 182 ADRLNVEFALIHKERKKANEVDRMVLVGDVKDRVAILVDDMADTCGTICHAADKLLSAGA 241
Query: 244 KSVIAIVTHGILSGKAIENINHSKLDRVVCTNTVPFEEKMLRCPKLDAIDISSVLAEAIR 303
V AI+THGI SG AI IN++ + VV TNT+P E+KM C K+ IDIS +LAEAIR
Sbjct: 242 TKVYAILTHGIFSGPAISRINNAAFEAVVVTNTIPQEDKMKHCTKIQVIDISMILAEAIR 301
Query: 304 RLHNGESISYLFKNYPL 320
R HNGES+SYLF + PL
Sbjct: 302 RTHNGESVSYLFSHVPL 318
>Hs4506127 [FE] KOG1448 Ribose-phosphate pyrophosphokinase
Length = 318
Score = 387 bits (994), Expect = e-107
Identities = 193/317 (60%), Positives = 250/317 (77%), Gaps = 2/317 (0%)
Query: 5 SIKLLAPDVHRNLAELVAKRLGLKLTNCKLKRDPSGEVSFSIGESVRDQDIFIVTQIGSG 64
+IK+ + H++L++ +A RLGL+L K+ + E IGESVR +D++IV Q G G
Sbjct: 3 NIKIFSGSSHQDLSQKIADRLGLELGKVVTKKFSNQETCVEIGESVRGEDVYIV-QSGCG 61
Query: 65 DVNDRVLELLIMINASKTASARRITAIIPNFPYARQDRKDKSRAPITAKLMADMLTTAGC 124
++ND ++ELLIMINA K ASA R+TA+IP FPYARQD+KDKSRAPI+AKL+A+ML+ AG
Sbjct: 62 EINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPISAKLVANMLSVAGA 121
Query: 125 DHVITMDLHASQIQGFFDVPVDNLYAEPSVVRYIKENVN-FKEAIIISPDAGGAKRAAGL 183
DH+ITMDLHASQIQGFFD+PVDNLYAEP+V+++I+EN++ ++ I+SPDAGGAKR +
Sbjct: 122 DHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIRENISEWRNCTIVSPDAGGAKRVTSI 181
Query: 184 ADRLDLNFALIHKERARANEVSRMVLVGDVSDKICIIVDDMADTCGTLAKAAEVLLENKA 243
ADRL+++FALIHKER +ANEV RMVLVGDV D++ I+VDDMADTCGT+ AA+ LL A
Sbjct: 182 ADRLNVDFALIHKERKKANEVDRMVLVGDVKDRVAILVDDMADTCGTICHAADKLLSAGA 241
Query: 244 KSVIAIVTHGILSGKAIENINHSKLDRVVCTNTVPFEEKMLRCPKLDAIDISSVLAEAIR 303
V AI+THGI SG AI IN++ + VV TNT+P E+KM C K+ IDIS +LAEAIR
Sbjct: 242 TRVYAILTHGIFSGPAISRINNACFEAVVVTNTIPQEDKMKHCSKIQVIDISMILAEAIR 301
Query: 304 RLHNGESISYLFKNYPL 320
R HNGES+SYLF + PL
Sbjct: 302 RTHNGESVSYLFSHVPL 318
>7294893 [FE] KOG1448 Ribose-phosphate pyrophosphokinase
Length = 318
Score = 383 bits (984), Expect = e-106
Identities = 193/316 (61%), Positives = 246/316 (77%), Gaps = 2/316 (0%)
Query: 5 SIKLLAPDVHRNLAELVAKRLGLKLTNCKLKRDPSGEVSFSIGESVRDQDIFIVTQIGSG 64
+IK+ + H +LA+ + RLG+ L K+ + E IGESVR +D++IV Q GSG
Sbjct: 3 NIKVFSGTSHPDLAQRIVDRLGIDLGKVVTKKFSNLETCVEIGESVRGEDVYIV-QSGSG 61
Query: 65 DVNDRVLELLIMINASKTASARRITAIIPNFPYARQDRKDKSRAPITAKLMADMLTTAGC 124
++ND ++ELLIMINA K ASA R+TA+IP FPYARQD+KDKSRAPI+AKL+A+ML+ AG
Sbjct: 62 EINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPISAKLVANMLSVAGA 121
Query: 125 DHVITMDLHASQIQGFFDVPVDNLYAEPSVVRYIKENV-NFKEAIIISPDAGGAKRAAGL 183
DH+ITMDLHASQIQGFFD+PVDNLYAEP+V+++IKEN+ +K +II+SPDAGGAKR +
Sbjct: 122 DHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIKENIPEWKNSIIVSPDAGGAKRVTSI 181
Query: 184 ADRLDLNFALIHKERARANEVSRMVLVGDVSDKICIIVDDMADTCGTLAKAAEVLLENKA 243
ADRL++ FALIHKER +ANEV+ MVLVGDV DKI I+VDDMADTCGT+ AA+ L+E A
Sbjct: 182 ADRLNVEFALIHKERKKANEVASMVLVGDVKDKIAILVDDMADTCGTIVHAADRLVEAGA 241
Query: 244 KSVIAIVTHGILSGKAIENINHSKLDRVVCTNTVPFEEKMLRCPKLDAIDISSVLAEAIR 303
V AI+THGI SG AI IN++ + VV TNT+P + M CPK+ ID+S + AEA+R
Sbjct: 242 TKVYAILTHGIFSGPAISRINNACFEAVVVTNTIPQDGHMRDCPKIQCIDVSMMFAEAVR 301
Query: 304 RLHNGESISYLFKNYP 319
R HNGES+SYLF N P
Sbjct: 302 RTHNGESVSYLFSNVP 317
>Hs20539448 [FE] KOG1448 Ribose-phosphate pyrophosphokinase
Length = 318
Score = 374 bits (959), Expect = e-103
Identities = 189/317 (59%), Positives = 247/317 (77%), Gaps = 2/317 (0%)
Query: 5 SIKLLAPDVHRNLAELVAKRLGLKLTNCKLKRDPSGEVSFSIGESVRDQDIFIVTQIGSG 64
+IK+ + H++L++ +A RLGL+L K+ + E I ESVR +D++IV Q G G
Sbjct: 3 NIKIFSGSSHQDLSQKIADRLGLELGKVVTKKFSNQETCVEIDESVRGEDVYIV-QSGCG 61
Query: 65 DVNDRVLELLIMINASKTASARRITAIIPNFPYARQDRKDKSRAPITAKLMADMLTTAGC 124
++ND ++ELLIMINA K ASA R+TA+IP FPYARQD+KDKSR+PI+AKL+A+ML+ AG
Sbjct: 62 EINDSLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRSPISAKLVANMLSIAGA 121
Query: 125 DHVITMDLHASQIQGFFDVPVDNLYAEPSVVRYIKENV-NFKEAIIISPDAGGAKRAAGL 183
DH+ITMDLHASQIQGFFD+PVDNLYAEP+V+++I+EN+ +K II+SPDAGGAKR +
Sbjct: 122 DHIITMDLHASQIQGFFDIPVDNLYAEPTVLKWIRENIPEWKNCIIVSPDAGGAKRVTSI 181
Query: 184 ADRLDLNFALIHKERARANEVSRMVLVGDVSDKICIIVDDMADTCGTLAKAAEVLLENKA 243
AD+L+++FALIHKER +ANEV +VLVGDV+D++ I+VDDMADTC T+ AA+ LL A
Sbjct: 182 ADQLNVDFALIHKERKKANEVDCIVLVGDVNDRVAILVDDMADTCVTICLAADKLLSAGA 241
Query: 244 KSVIAIVTHGILSGKAIENINHSKLDRVVCTNTVPFEEKMLRCPKLDAIDISSVLAEAIR 303
V AI+THGI SG AI IN + + VV TNT+P +EKM C K+ IDIS +LAEAIR
Sbjct: 242 TRVYAILTHGIFSGPAISRINTACFEAVVVTNTIPQDEKMKHCSKIRVIDISMILAEAIR 301
Query: 304 RLHNGESISYLFKNYPL 320
R HNGES+SYLF + PL
Sbjct: 302 RTHNGESVSYLFSHVPL 318
>CE27199 [FE] KOG1448 Ribose-phosphate pyrophosphokinase
Length = 419
Score = 371 bits (953), Expect = e-103
Identities = 181/317 (57%), Positives = 245/317 (77%), Gaps = 2/317 (0%)
Query: 5 SIKLLAPDVHRNLAELVAKRLGLKLTNCKLKRDPSGEVSFSIGESVRDQDIFIVTQIGSG 64
+IK+ + H +L+ + +RL L+++ LK+ + E + IGESVR +D++I+ Q +G
Sbjct: 103 NIKVFSGSSHPDLSTRICERLQLEVSKASLKKFSNKETNVEIGESVRGEDVYII-QSAAG 161
Query: 65 DVNDRVLELLIMINASKTASARRITAIIPNFPYARQDRKDKSRAPITAKLMADMLTTAGC 124
++ND ++ELLIMINA K AS+ R+ A+IP FPYARQD+KDKSRAPI+AKL+A+ML+ AG
Sbjct: 162 EINDNLMELLIMINACKIASSCRVAAVIPAFPYARQDKKDKSRAPISAKLVANMLSVAGA 221
Query: 125 DHVITMDLHASQIQGFFDVPVDNLYAEPSVVRYIKENV-NFKEAIIISPDAGGAKRAAGL 183
DH+ITMDLHASQIQGFFD+PVDNLYAEP++++YIKE++ N++ ++I+SPDAGGAKR +
Sbjct: 222 DHIITMDLHASQIQGFFDIPVDNLYAEPAILKYIKESIPNWQTSVIVSPDAGGAKRVTSI 281
Query: 184 ADRLDLNFALIHKERARANEVSRMVLVGDVSDKICIIVDDMADTCGTLAKAAEVLLENKA 243
ADRL+++FALIHKE RANEV +M LVG V K+ I+VDDMADTCGT+ AA+ L+E A
Sbjct: 282 ADRLNVDFALIHKESKRANEVEKMTLVGSVEGKVAILVDDMADTCGTICMAADKLVEAGA 341
Query: 244 KSVIAIVTHGILSGKAIENINHSKLDRVVCTNTVPFEEKMLRCPKLDAIDISSVLAEAIR 303
V A HGI SG A+ +N SK + VV TNT+P +E M +C K+ IDIS +LAEAIR
Sbjct: 342 DKVYAFCVHGIFSGPALTRLNASKFEAVVVTNTIPQDENMKKCSKIQCIDISMILAEAIR 401
Query: 304 RLHNGESISYLFKNYPL 320
R HNGES+SYLF + P+
Sbjct: 402 RTHNGESVSYLFSHVPI 418
>CE00745 [FE] KOG1448 Ribose-phosphate pyrophosphokinase
Length = 377
Score = 371 bits (953), Expect = e-103
Identities = 181/317 (57%), Positives = 245/317 (77%), Gaps = 2/317 (0%)
Query: 5 SIKLLAPDVHRNLAELVAKRLGLKLTNCKLKRDPSGEVSFSIGESVRDQDIFIVTQIGSG 64
+IK+ + H +L+ + +RL L+++ LK+ + E + IGESVR +D++I+ Q +G
Sbjct: 61 NIKVFSGSSHPDLSTRICERLQLEVSKASLKKFSNKETNVEIGESVRGEDVYII-QSAAG 119
Query: 65 DVNDRVLELLIMINASKTASARRITAIIPNFPYARQDRKDKSRAPITAKLMADMLTTAGC 124
++ND ++ELLIMINA K AS+ R+ A+IP FPYARQD+KDKSRAPI+AKL+A+ML+ AG
Sbjct: 120 EINDNLMELLIMINACKIASSCRVAAVIPAFPYARQDKKDKSRAPISAKLVANMLSVAGA 179
Query: 125 DHVITMDLHASQIQGFFDVPVDNLYAEPSVVRYIKENV-NFKEAIIISPDAGGAKRAAGL 183
DH+ITMDLHASQIQGFFD+PVDNLYAEP++++YIKE++ N++ ++I+SPDAGGAKR +
Sbjct: 180 DHIITMDLHASQIQGFFDIPVDNLYAEPAILKYIKESIPNWQTSVIVSPDAGGAKRVTSI 239
Query: 184 ADRLDLNFALIHKERARANEVSRMVLVGDVSDKICIIVDDMADTCGTLAKAAEVLLENKA 243
ADRL+++FALIHKE RANEV +M LVG V K+ I+VDDMADTCGT+ AA+ L+E A
Sbjct: 240 ADRLNVDFALIHKESKRANEVEKMTLVGSVEGKVAILVDDMADTCGTICMAADKLVEAGA 299
Query: 244 KSVIAIVTHGILSGKAIENINHSKLDRVVCTNTVPFEEKMLRCPKLDAIDISSVLAEAIR 303
V A HGI SG A+ +N SK + VV TNT+P +E M +C K+ IDIS +LAEAIR
Sbjct: 300 DKVYAFCVHGIFSGPALTRLNASKFEAVVVTNTIPQDENMKKCSKIQCIDISMILAEAIR 359
Query: 304 RLHNGESISYLFKNYPL 320
R HNGES+SYLF + P+
Sbjct: 360 RTHNGESVSYLFSHVPI 376
>7294894 [FE] KOG1448 Ribose-phosphate pyrophosphokinase
Length = 341
Score = 370 bits (950), Expect = e-102
Identities = 193/339 (56%), Positives = 246/339 (71%), Gaps = 25/339 (7%)
Query: 5 SIKLLAPDVHRNLAELVAKRLGLKLTNCKLKRDPSGEVSFSIGESVRDQDIFIVTQIGSG 64
+IK+ + H +LA+ + RLG+ L K+ + E IGESVR +D++IV Q GSG
Sbjct: 3 NIKVFSGTSHPDLAQRIVDRLGIDLGKVVTKKFSNLETCVEIGESVRGEDVYIV-QSGSG 61
Query: 65 DVNDRVLELLIMINASKTASARRITAIIPNFPYARQDRKDK------------------- 105
++ND ++ELLIMINA K ASA R+TA+IP FPYARQD+KDK
Sbjct: 62 EINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKLAGSEDNAESKKLAKKNYD 121
Query: 106 ----SRAPITAKLMADMLTTAGCDHVITMDLHASQIQGFFDVPVDNLYAEPSVVRYIKEN 161
SRAPI+AKL+A+ML+ AG DH+ITMDLHASQIQGFFD+PVDNLYAEP+V+++IKEN
Sbjct: 122 WKFRSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIKEN 181
Query: 162 V-NFKEAIIISPDAGGAKRAAGLADRLDLNFALIHKERARANEVSRMVLVGDVSDKICII 220
+ +K +II+SPDAGGAKR +ADRL++ FALIHKER +ANEV+ MVLVGDV DKI I+
Sbjct: 182 IPEWKNSIIVSPDAGGAKRVTSIADRLNVEFALIHKERKKANEVASMVLVGDVKDKIAIL 241
Query: 221 VDDMADTCGTLAKAAEVLLENKAKSVIAIVTHGILSGKAIENINHSKLDRVVCTNTVPFE 280
VDDMADTCGT+ AA+ L+E A V AI+THGI SG AI IN++ + VV TNT+P +
Sbjct: 242 VDDMADTCGTIVHAADRLVEAGATKVYAILTHGIFSGPAISRINNACFEAVVVTNTIPQD 301
Query: 281 EKMLRCPKLDAIDISSVLAEAIRRLHNGESISYLFKNYP 319
M CPK+ ID+S + AEA+RR HNGES+SYLF N P
Sbjct: 302 GHMRDCPKIQCIDVSMMFAEAVRRTHNGESVSYLFSNVP 340
>CE29454 [FE] KOG1448 Ribose-phosphate pyrophosphokinase
Length = 318
Score = 368 bits (945), Expect = e-102
Identities = 179/308 (58%), Positives = 240/308 (77%), Gaps = 2/308 (0%)
Query: 14 HRNLAELVAKRLGLKLTNCKLKRDPSGEVSFSIGESVRDQDIFIVTQIGSGDVNDRVLEL 73
H +L+ + +RL L+++ LK+ + E + IGESVR +D++I+ Q +G++ND ++EL
Sbjct: 11 HPDLSTRICERLQLEVSKASLKKFSNKETNVEIGESVRGEDVYII-QSAAGEINDNLMEL 69
Query: 74 LIMINASKTASARRITAIIPNFPYARQDRKDKSRAPITAKLMADMLTTAGCDHVITMDLH 133
LIMINA K AS+ R+ A+IP FPYARQD+KDKSRAPI+AKL+A+ML+ AG DH+ITMDLH
Sbjct: 70 LIMINACKIASSCRVAAVIPAFPYARQDKKDKSRAPISAKLVANMLSVAGADHIITMDLH 129
Query: 134 ASQIQGFFDVPVDNLYAEPSVVRYIKENV-NFKEAIIISPDAGGAKRAAGLADRLDLNFA 192
ASQIQGFFD+PVDNLYAEP++++YIKE++ N++ ++I+SPDAGGAKR +ADRL+++FA
Sbjct: 130 ASQIQGFFDIPVDNLYAEPAILKYIKESIPNWQTSVIVSPDAGGAKRVTSIADRLNVDFA 189
Query: 193 LIHKERARANEVSRMVLVGDVSDKICIIVDDMADTCGTLAKAAEVLLENKAKSVIAIVTH 252
LIHKE RANEV +M LVG V K+ I+VDDMADTCGT+ AA+ L+E A V A H
Sbjct: 190 LIHKESKRANEVEKMTLVGSVEGKVAILVDDMADTCGTICMAADKLVEAGADKVYAFCVH 249
Query: 253 GILSGKAIENINHSKLDRVVCTNTVPFEEKMLRCPKLDAIDISSVLAEAIRRLHNGESIS 312
GI SG A+ +N SK + VV TNT+P +E M +C K+ IDIS +LAEAIRR HNGES+S
Sbjct: 250 GIFSGPALTRLNASKFEAVVVTNTIPQDENMKKCSKIQCIDISMILAEAIRRTHNGESVS 309
Query: 313 YLFKNYPL 320
YLF + P+
Sbjct: 310 YLFSHVPI 317
>SPBC3D6.06c [FE] KOG1448 Ribose-phosphate pyrophosphokinase
Length = 341
Score = 266 bits (681), Expect = 2e-71
Identities = 152/336 (45%), Positives = 211/336 (62%), Gaps = 29/336 (8%)
Query: 5 SIKLLAPDVHRNLAELVAKRLGLKLTNCKLKRDPSGEVSFSIGESVRDQDIFIVTQIGSG 64
++ + + H L E + + L L + +L + +GE S I +SVR D++IV+ SG
Sbjct: 3 NLVVFGTESHPKLTESICEHLCLDIGRVELSKFSNGETSVRIKQSVRGCDVYIVSP-ASG 61
Query: 65 DVNDRVLELLIMINASKTASARRITAIIPNFPYARQ-DRKDK-SRAPIT----------- 111
VND ++ELLIMI+A KTASA+++TA++P FPY+RQ D+K S AP++
Sbjct: 62 QVNDHLMELLIMISACKTASAKKVTAVLPVFPYSRQPDQKFSFSGAPLSDLQDAVVPCKK 121
Query: 112 -----------AKLMADMLTTAGCDHVITMDLHASQIQGFFDVPVDNLYAEPSVVRYIKE 160
L+AD+L +G DH+ITMDLH Q QGFFD+PVDNL+ P + YI
Sbjct: 122 QTGYHPWIAQSGTLVADLLMCSGADHIITMDLHDPQFQGFFDIPVDNLFGRPLLKHYISL 181
Query: 161 NV-NFKEAIIISPDAGGAKRAAGLADRLDLNFALIHKERARANEVSRMVLVGDVSDKICI 219
N+ N+ A+I+SPDAGGAKRA +AD L L+FALIHK R S M LVGDV +K+ I
Sbjct: 182 NIPNYHNAVIVSPDAGGAKRATAIADALGLDFALIHKNRRHEYGTSLM-LVGDVQNKVAI 240
Query: 220 IVDDMADTCGTLAKAAEVLLENKAKSVIAIVTHGILSGKAIENINHSKLDRVVCTNTVPF 279
++DD+ DT TL +AAE + E+ A + A+VTH +LSG AIE + S +D+++ TNT P
Sbjct: 241 LIDDLIDTAYTLVRAAEFVKEHGASKIYALVTHCVLSGDAIERVKLSCIDKLIVTNTAPQ 300
Query: 280 EEKMLRCPKLDAIDISSVLAEAIRRLHNGESISYLF 315
C D ID++ AEAIRR+HNGESIS L+
Sbjct: 301 TITPSGC--FDIIDVAPTFAEAIRRIHNGESISILY 334
>Hs4506133 [EF] KOG1503 Phosphoribosylpyrophosphate synthetase-associated
protein
Length = 369
Score = 252 bits (643), Expect = 6e-67
Identities = 139/336 (41%), Positives = 203/336 (60%), Gaps = 34/336 (10%)
Query: 17 LAELVAKRLGLKLTNCKLKRDPSGEVSFSIGESVRDQDIFIVTQIGSGDVNDRVLELLIM 76
L++ +A+RLG+++ ++ ++P+ E I ESVR +D+FI+ + S DVN ++ELLIM
Sbjct: 34 LSKKIAERLGVEMGKVQVYQEPNRETRVQIQESVRGKDVFIIQTV-SKDVNTTIMELLIM 92
Query: 77 INASKTASARRITAIIPNFPYARQDRKDKSRAPITAKLMADMLTTAGCDHVITMDLHASQ 136
+ A KT+ A+ I +IP FPY++Q + K R I +KL+A M+ AG H+ITMDLH +
Sbjct: 93 VYACKTSCAKSIIGVIPYFPYSKQCKMRK-RGSIVSKLLASMMCKAGLTHLITMDLHQKE 151
Query: 137 IQGFFDVPVDNLYAEPSVVRYIKENV-NFKEAIIISPDAGGAKRAAGLADRLDLNFALIH 195
IQGFF++PVDNL A P +++YI+E + +++ A+I++ AKRA A+RL L A+IH
Sbjct: 152 IQGFFNIPVDNLRASPFLLQYIQEEIPDYRNAVIVAKSPASAKRAQSFAERLRLGIAVIH 211
Query: 196 KERARA-------------------------------NEVSRMVLVGDVSDKICIIVDDM 224
E A E + +VGDV +I IIVDD+
Sbjct: 212 GEAQDAESDLVDGRHSPPMVRSVAAIHPSLEIPMLIPKEKPPITVVGDVGGRIAIIVDDI 271
Query: 225 ADTCGTLAKAAEVLLENKAKSVIAIVTHGILSGKAIENINHSKLDRVVCTNTVPFEEKML 284
D + AAE L E A + + THG+LS A I S +D VV TNT+P E + L
Sbjct: 272 IDDVDSFLAAAETLKERGAYKIFVMATHGLLSSDAPRRIEESAIDEVVVTNTIPHEVQKL 331
Query: 285 RCPKLDAIDISSVLAEAIRRLHNGESISYLFKNYPL 320
+CPK+ +DIS +L+EAIRR+HNGES+SYLF+N L
Sbjct: 332 QCPKIKTVDISMILSEAIRRIHNGESMSYLFRNIGL 367
>Hs4506131 [EF] KOG1503 Phosphoribosylpyrophosphate synthetase-associated
protein
Length = 356
Score = 252 bits (643), Expect = 6e-67
Identities = 146/332 (43%), Positives = 195/332 (57%), Gaps = 33/332 (9%)
Query: 17 LAELVAKRLGLKLTNCKLKRDPSGEVSFSIGESVRDQDIFIVTQIGSGDVNDRVLELLIM 76
LA+ + +RLG +L + ++ +GE I E VR QDIFI+ I DVN V+ELLIM
Sbjct: 22 LAKRITERLGAELGKSVVYQETNGETRVEIKEFVRGQDIFIIQTIPR-DVNTAVMELLIM 80
Query: 77 INASKTASARRITAIIPNFPYARQDRKDKSRAPITAKLMADMLTTAGCDHVITMDLHASQ 136
A KTA AR I +IP FPY++Q + K R I KL+A ML AG H+ITMDLH +
Sbjct: 81 AYALKTACARNIIGVIPYFPYSKQSKMRK-RGSIVCKLLASMLAKAGLTHIITMDLHQKE 139
Query: 137 IQGFFDVPVDNLYAEPSVVRYIKENV-NFKEAIIISPDAGGAKRAAGLADRLDLNFALIH 195
IQGFF PVDNL A P +++YI+E + N++ A+I++ AKRA A+RL L A+IH
Sbjct: 140 IQGFFSFPVDNLRASPFLLQYIQEEIPNYRNAVIVAKSPDAAKRAQSYAERLRLGLAVIH 199
Query: 196 KER------------------------------ARANEVSRMVLVGDVSDKICIIVDDMA 225
E A E + +VGDV +I IIVDD+
Sbjct: 200 GEAQCTELDMDDGRHSPPMVKNATVHPGLELPLMMAKEKPPITVVGDVGGRIAIIVDDII 259
Query: 226 DTCGTLAKAAEVLLENKAKSVIAIVTHGILSGKAIENINHSKLDRVVCTNTVPFEEKMLR 285
D + AAE+L E A + + THGILS +A I S +D VV TNTVP E + L+
Sbjct: 260 DDVESFVAAAEILKERGAYKIYVMATHGILSAEAPRLIEESSVDEVVVTNTVPHEVQKLQ 319
Query: 286 CPKLDAIDISSVLAEAIRRLHNGESISYLFKN 317
CPK+ +DIS +L+EAIRR+HNGES++YLF+N
Sbjct: 320 CPKIKTVDISLILSEAIRRIHNGESMAYLFRN 351
>At1g32380 [FE] KOG1448 Ribose-phosphate pyrophosphokinase
Length = 400
Score = 232 bits (591), Expect = 6e-61
Identities = 122/312 (39%), Positives = 195/312 (62%), Gaps = 4/312 (1%)
Query: 6 IKLLAPDVHRNLAELVAKRLGLKLTNCKLKRDPSGEVSFSIGESVRDQDIFIVTQIGSGD 65
+KL + + L++ +A +GL+L +KR GE+ + ESVR D+F+V Q
Sbjct: 90 LKLFSGTANPALSQEIAWYMGLELGKVSIKRFADGEIYVQLKESVRGCDVFLV-QPTCTP 148
Query: 66 VNDRVLELLIMINASKTASARRITAIIPNFPYARQDRKDKSRAPITAKLMADMLTTAGCD 125
N+ ++ELLIM++A + ASA+++TA+IP F YAR DRK + R I AKL+A+++T AG D
Sbjct: 149 TNENLMELLIMVDACRRASAKKVTAVIPYFGYARADRKTQGRESIAAKLVANLITEAGAD 208
Query: 126 HVITMDLHASQIQGFFDVPVDNLYAEPSVVRYI-KENVNFKEAIIISPDAGGAKRAAGLA 184
V+ DLH+ Q G+FD+PVD++Y +P ++ Y+ ++++ ++ +++SPD GG RA A
Sbjct: 209 RVLACDLHSGQSMGYFDIPVDHVYCQPVILDYLASKSISSEDLVVVSPDVGGVARARAFA 268
Query: 185 DRL-DLNFALIHKERARANEVSRMVLVGDVSDKICIIVDDMADTCGTLAKAAEVLLENKA 243
+L D A++ K R N M L+GDV K+ ++VDD+ DT GT+ K A +L E A
Sbjct: 269 KKLSDAPLAIVDKRRHGHNVAEVMNLIGDVKGKVAVMVDDIIDTAGTIVKGAALLHEEGA 328
Query: 244 KSVIAIVTHGILSGKAIENINHSKLDRVVCTNTVPFEEKMLRCPKLDAIDISSVLAEAIR 303
+ V A TH + S AIE ++ L V+ TNT+P EK P+L + ++++L E I
Sbjct: 329 REVYACCTHAVFSPPAIERLSSGLLQEVIVTNTLPVAEKNY-FPQLTILSVANLLGETIW 387
Query: 304 RLHNGESISYLF 315
R+H+ S+S +F
Sbjct: 388 RVHDDSSVSSIF 399
>At2g35390 [FE] KOG1448 Ribose-phosphate pyrophosphokinase
Length = 352
Score = 231 bits (589), Expect = 1e-60
Identities = 123/312 (39%), Positives = 194/312 (61%), Gaps = 4/312 (1%)
Query: 6 IKLLAPDVHRNLAELVAKRLGLKLTNCKLKRDPSGEVSFSIGESVRDQDIFIVTQIGSGD 65
+KL + + LA+ +A +GL L +KR GE+ + ESVR D+++V Q
Sbjct: 42 LKLFSGTANPALAQEIAWYMGLDLGKVNIKRFADGEIYVQLQESVRGCDVYLV-QPTCTP 100
Query: 66 VNDRVLELLIMINASKTASARRITAIIPNFPYARQDRKDKSRAPITAKLMADMLTTAGCD 125
N+ ++ELLIM++A + ASA+++TA+IP F YAR DRK + R I AKL+A+++T AG D
Sbjct: 101 TNENLMELLIMVDACRRASAKKVTAVIPYFGYARADRKTQGRESIAAKLVANLITEAGAD 160
Query: 126 HVITMDLHASQIQGFFDVPVDNLYAEPSVVRYI-KENVNFKEAIIISPDAGGAKRAAGLA 184
V+ DLH+ Q G+FD+PVD++Y +P ++ Y+ +++ ++ +++SPD GG RA A
Sbjct: 161 RVLACDLHSGQSMGYFDIPVDHVYCQPVILDYLASKSIPSEDLVVVSPDVGGVARARAFA 220
Query: 185 DRL-DLNFALIHKERARANEVSRMVLVGDVSDKICIIVDDMADTCGTLAKAAEVLLENKA 243
+L D A++ K R+ N M L+GDV K+ I+VDDM DT GT+ K A +L + A
Sbjct: 221 KKLSDAPLAIVDKRRSGHNVAEVMNLIGDVRGKVAIMVDDMIDTAGTIVKGAALLHQEGA 280
Query: 244 KSVIAIVTHGILSGKAIENINHSKLDRVVCTNTVPFEEKMLRCPKLDAIDISSVLAEAIR 303
+ V A TH + S AIE ++ L V+ TNT+P EK P+L + ++++L E I
Sbjct: 281 REVYACCTHAVFSPPAIERLSGGLLQEVIVTNTLPVAEKNY-FPQLTILSVANLLGETIW 339
Query: 304 RLHNGESISYLF 315
R+H+ S+S +F
Sbjct: 340 RVHDDSSVSSIF 351
>At2g44530 [FE] KOG1448 Ribose-phosphate pyrophosphokinase
Length = 386
Score = 226 bits (576), Expect = 3e-59
Identities = 121/312 (38%), Positives = 191/312 (60%), Gaps = 4/312 (1%)
Query: 3 TNSIKLLAPDVHRNLAELVAKRLGLKLTNCKLKRDPSGEVSFSIGESVRDQDIFIVTQIG 62
T +++ + + LA+ ++ LGL L K+KR GE+ + ESVR D+F+V Q
Sbjct: 75 TTRLRIFSGTANPILAQEISCYLGLDLGKIKIKRFADGEIYVQLQESVRGCDVFLV-QPT 133
Query: 63 SGDVNDRVLELLIMINASKTASARRITAIIPNFPYARQDRKDKSRAPITAKLMADMLTTA 122
N+ ++ELL+MI+A + ASA+ ITA+IP F YAR DRK + R I AKL+A+++T +
Sbjct: 134 CPPANENLMELLVMIDACRRASAKTITAVIPYFGYARADRKTQGRESIAAKLVANLITQS 193
Query: 123 GCDHVITMDLHASQIQGFFDVPVDNLYAEPSVVRYI-KENVNFKEAIIISPDAGGAKRAA 181
G D V+ DLH+ Q G+FD+PVD++Y +P ++ Y+ + ++ ++ +++SPD GG RA
Sbjct: 194 GADRVLACDLHSGQSMGYFDIPVDHVYGQPVILDYLASKAISSEDLVVVSPDVGGVARAR 253
Query: 182 GLADRL-DLNFALIHKERARANEVSRMVLVGDVSDKICIIVDDMADTCGTLAKAAEVLLE 240
A +L D A++ K R N M L+GDV K+ I+VDDM DT GT++K A +L +
Sbjct: 254 AFAKKLSDAPLAIVDKRRHGHNVAEVMNLIGDVKGKVAIMVDDMIDTAGTISKGAALLHQ 313
Query: 241 NKAKSVIAIVTHGILSGKAIENINHSKLDRVVCTNTVPFEEKMLRCPKLDAIDISSVLAE 300
A+ V A TH + S AI ++ V+ TNT+P EK P+L + ++++L E
Sbjct: 314 EGAREVYACTTHAVFSPPAISRLSSGLFQEVIITNTIPLSEKNY-FPQLTVLSVANLLGE 372
Query: 301 AIRRLHNGESIS 312
I R+H+ S+S
Sbjct: 373 TIWRVHDDCSVS 384
>7301964 [EF] KOG1503 Phosphoribosylpyrophosphate synthetase-associated
protein
Length = 386
Score = 215 bits (547), Expect = 8e-56
Identities = 134/382 (35%), Positives = 208/382 (54%), Gaps = 65/382 (17%)
Query: 2 ATNSIKLLAPDVHRNLAELVAKRLGLKLTNCKLKRDPSGEVSFSIGESVRDQDIFIVTQI 61
+T+ I ++ + H +LA +VA+R+G+K C + + E I +SVR +DI+I+ Q
Sbjct: 5 STSDIVIINGNSHPDLANMVAERMGIKNGGCSVFHKSNRETIVEISDSVRGKDIYII-QT 63
Query: 62 GSGDVNDRVLELLIMINASKTASARRITAIIPNFPYARQDRKDKSRAPITAKLMADMLTT 121
G+ D N+ ++ELLIM A KT+SAR I +IP PY++Q + K R I +KL+A M+ T
Sbjct: 64 GTKDANNNIMELLIMAYACKTSSARSIVGVIPYLPYSKQCKMRK-RGCIVSKLLAKMMCT 122
Query: 122 AGCDHVITMDLHASQIQGFFDVPVDNLYAEPSVVRYIKENV-NFKEAIIISPDAGGAKRA 180
+G H+ITMDLH +IQGFFD+PVDNL A P +++YI+E++ +++ ++I++ + G AK+A
Sbjct: 123 SGLTHIITMDLHQKEIQGFFDIPVDNLRASPFLLQYIQESIPDYRNSVIVARNPGVAKKA 182
Query: 181 AGLADRLDLNFALIHKER------------------------------------------ 198
A+RL L A+IH E+
Sbjct: 183 NSYAERLRLGLAVIHGEQKETDADEVDGRYSPPPTSAYSNLLGNSVEMCLPATPRNSTPQ 242
Query: 199 ------ARANEVSRMVLVGDVSDKICIIVDDMADTCGTLAKAAEVLLENKAKSVIA---- 248
AR S V V + K+ + + D G +A + L+++ V A
Sbjct: 243 HAPTSSARQRTTSVSVGVPEHIVKVKPPLTIVGDVSGRIAIMVDDLIDDVQAFVAAAEML 302
Query: 249 ----------IVTHGILSGKAIENINHSKLDRVVCTNTVPFEEKMLRCPKLDAIDISSVL 298
+ THG+LS A ++ S +D +V TNT+P E + L+C K+ IDIS ++
Sbjct: 303 KENGACKIYVLATHGLLSSDAPRQLDESPIDEIVVTNTIPHEIQKLQCHKIKTIDISILI 362
Query: 299 AEAIRRLHNGESISYLFKNYPL 320
AEAIRR+HN ES+SYLF+N L
Sbjct: 363 AEAIRRIHNKESMSYLFRNVTL 384
>CE03789 [EF] KOG1503 Phosphoribosylpyrophosphate synthetase-associated
protein
Length = 353
Score = 211 bits (537), Expect = 1e-54
Identities = 124/347 (35%), Positives = 199/347 (56%), Gaps = 30/347 (8%)
Query: 2 ATNSIKLLAPDVHRNLAELVAKRLGLKLTNCKLKRDPSGEVSFSIGESVRDQDIFIVTQI 61
A++ + LL + H LA++V++RL ++L + + E S I +SVR + +FI+ Q
Sbjct: 7 ASSGMVLLTGNSHPELAKMVSERLEIRLGEATVYNKTNRETSVDIKQSVRGKHVFIL-QS 65
Query: 62 GSGDVNDRVLELLIMINASKTASARRITAIIPNFPYARQDRKDKSRAPITAKLMADMLTT 121
GS +VN+ V+ELL++I A KT+ ++ IT I+P PY++Q R + R+ I KL+A+M+
Sbjct: 66 GSKNVNNDVMELLVLIYACKTSMSKTITVIMPYLPYSKQCRMLR-RSSIAMKLVAEMICK 124
Query: 122 AGCDHVITMDLHASQIQGFFDVPVDNLYAEPSVVRYIKENV-NFKEAIIISPDAGGAKRA 180
AG ++++DL+ +IQGFF PVDNL A P +++IK N+ ++K AII++ G +A
Sbjct: 125 AGASRLVSLDLYKKEIQGFFSCPVDNLRASPFFLQHIKTNIPDYKNAIIVAKSPGVMNKA 184
Query: 181 AGLADRLDLNFALIHKER---------------------------ARANEVSRMVLVGDV 213
ADRL L A+IH E+ + + + +VGDV
Sbjct: 185 TSYADRLRLGVAVIHGEQKDEEESGLEDGRQSPPPNVTSYDFLPAQESKQKPPLTVVGDV 244
Query: 214 SDKICIIVDDMADTCGTLAKAAEVLLENKAKSVIAIVTHGILSGKAIENINHSKLDRVVC 273
+I I+VDD+ D + AAEVL A + I THG+LS A + S + V+
Sbjct: 245 GGRIAIMVDDIIDDAQSFVAAAEVLKARGAYKIYVIATHGVLSSDAPALLEASPITEVIV 304
Query: 274 TNTVPFEEKMLRCPKLDAIDISSVLAEAIRRLHNGESISYLFKNYPL 320
TNTVP + + +RC K+ +D+S ++ EAIRR+ + ES+ LF++ L
Sbjct: 305 TNTVPHDLQKMRCHKIKTVDVSLMICEAIRRIFHNESMGQLFRDVTL 351
>YKL181w [FE] KOG1448 Ribose-phosphate pyrophosphokinase
Length = 427
Score = 200 bits (508), Expect = 3e-51
Identities = 93/199 (46%), Positives = 145/199 (72%), Gaps = 2/199 (1%)
Query: 7 KLLAPDVHRNLAELVAKRLGLKLTNCKLKRDPSGEVSFSIGESVRDQDIFIVTQIGSGDV 66
K+ + H L +V +RLG++ C LK+ +GE S IG SVRD+D++++ Q GS +
Sbjct: 5 KIFVGNSHPELGNMVCQRLGIEPAPCTLKKFANGETSVQIGVSVRDEDVYVI-QSGSPSI 63
Query: 67 NDRVLELLIMINASKTASARRITAIIPNFPYARQDRKDKSRAPITAKLMADMLTTAGCDH 126
ND ++ELLI+++A + SAR+ITA+IP FPY++Q + + R ITA+++A++L AG DH
Sbjct: 64 NDDIMELLILVSACRGGSARKITAVIPQFPYSKQCKMKRHRGAITARMLANLLVMAGADH 123
Query: 127 VITMDLHASQIQGFFDVPVDNLYAEPSVVRYIKENV-NFKEAIIISPDAGGAKRAAGLAD 185
V++MDLHASQ+QGFF PVDNLY PS+ ++I+ENV ++++A+++S + GG KR LAD
Sbjct: 124 VVSMDLHASQMQGFFTKPVDNLYGGPSLAKWIRENVEDYEDAVVVSKNPGGTKRVTALAD 183
Query: 186 RLDLNFALIHKERARANEV 204
L +NFA+IH +R R+ ++
Sbjct: 184 SLKINFAMIHTDRRRSKDL 202
Score = 85.9 bits (211), Expect = 7e-17
Identities = 51/112 (45%), Positives = 68/112 (60%), Gaps = 3/112 (2%)
Query: 207 MVLVGDVSDKICIIVDDMADTCGTLAKAAEVLLEN-KAKSVIAIVTHGILSGKAIENINH 265
+ LVG+V + II+DDM D G+ AAE L++N AK V + THGI +G +E +
Sbjct: 310 ITLVGNVRGRSAIILDDMIDRPGSFISAAEHLVQNCGAKKVYVVATHGIFTGDCLEELEK 369
Query: 266 SK-LDRVVCTNTVPFE-EKMLRCPKLDAIDISSVLAEAIRRLHNGESISYLF 315
S +D +V TNT P E++ KL ID+S + AE IRR H GESIS LF
Sbjct: 370 SDAIDTIVVTNTYPISGERIAGSKKLVTIDVSPIFAECIRRDHYGESISVLF 421
>SPAC4A8.14 [FE] KOG1448 Ribose-phosphate pyrophosphokinase
Length = 409
Score = 200 bits (508), Expect = 3e-51
Identities = 102/203 (50%), Positives = 148/203 (72%), Gaps = 2/203 (0%)
Query: 5 SIKLLAPDVHRNLAELVAKRLGLKLTNCKLKRDPSGEVSFSIGESVRDQDIFIVTQIGSG 64
S ++ H L L++ RLG+ + LKR +GE S I ESVRD+D+FI+ Q GS
Sbjct: 3 SATIIGGGSHPELLHLISNRLGITPCDVSLKRFANGETSVEIRESVRDKDVFIL-QSGSS 61
Query: 65 DVNDRVLELLIMINASKTASARRITAIIPNFPYARQDRKDKSRAPITAKLMADMLTTAGC 124
VND ++ELLI+I+A K SA+RITA++P FPY++Q + K R ITA+++A++LT AG
Sbjct: 62 TVNDSLMELLIIISACKGGSAKRITAVMPYFPYSKQSKMRKYRDAITARMVANLLTVAGV 121
Query: 125 DHVITMDLHASQIQGFFDVPVDNLYAEPSVVRYIKENV-NFKEAIIISPDAGGAKRAAGL 183
DH+IT+DLHASQ+QGFF PVDNLYAEP++ +I+ NV +++EA+++S + GGAKR L
Sbjct: 122 DHIITLDLHASQMQGFFTRPVDNLYAEPNIAEWIRRNVDDWEEAVVVSKNPGGAKRVTSL 181
Query: 184 ADRLDLNFALIHKERARANEVSR 206
AD L+L+FALI+ +R R++ S+
Sbjct: 182 ADTLNLDFALINTDRQRSSHFSQ 204
Score = 92.4 bits (228), Expect = 8e-19
Identities = 52/113 (46%), Positives = 74/113 (65%), Gaps = 3/113 (2%)
Query: 207 MVLVGDVSDKICIIVDDMADTCGTLAKAAEVLLEN-KAKSVIAIVTHGILSGKAIENINH 265
+ LVGDV+ K +++DD + A+E L++ AK VI I THGI K ++++
Sbjct: 294 ITLVGDVNGKTALLIDDTIENPTAFIVASEHLVKRCGAKRVIVIGTHGIFQNKCLKDLQS 353
Query: 266 SK-LDRVVCTNTVPFE-EKMLRCPKLDAIDISSVLAEAIRRLHNGESISYLFK 316
+ ++++V TNT P + + +L C KL IDIS VLAEAIRR HNGESIS+LFK
Sbjct: 354 CEYIEQIVVTNTYPIKPQAVLECDKLTVIDISGVLAEAIRRTHNGESISFLFK 406
>YOL061w [FE] KOG1448 Ribose-phosphate pyrophosphokinase
Length = 496
Score = 114 bits (284), Expect = 2e-25
Identities = 54/116 (46%), Positives = 83/116 (71%), Gaps = 2/116 (1%)
Query: 204 VSRMVLVGDVSDKICIIVDDMADTCGTLAKAAEVLLENKAKSVIAIVTHGILSGKAIENI 263
V +LVGDV +K+CIIVDD+ DT T+ +AA++L + + V A++THG+ SG A+E I
Sbjct: 379 VQTTMLVGDVRNKVCIIVDDLVDTSYTITRAAKLLKDQGSTKVYALITHGVFSGDALERI 438
Query: 264 NHSKLDRVVCTNTVPFEEKM--LRCPKLDAIDISSVLAEAIRRLHNGESISYLFKN 317
S +D+++ +NTVP + + L ++D ID+S ++ EAIRR+HNGESIS LF++
Sbjct: 439 GQSSIDKLIISNTVPQDRTLQYLGKDRVDVIDVSCIIGEAIRRIHNGESISMLFEH 494
Score = 112 bits (279), Expect = 9e-25
Identities = 52/86 (60%), Positives = 68/86 (78%), Gaps = 1/86 (1%)
Query: 114 LMADMLTTAGCDHVITMDLHASQIQGFFDVPVDNLYAEPSVVRYIKENV-NFKEAIIISP 172
L+A +L+ AG DHVITMDLH Q GFFD+PVDNLY +P YI+ + ++++A+I+SP
Sbjct: 225 LIAHLLSAAGADHVITMDLHDPQFPGFFDIPVDNLYCKPIAQNYIQHRIPDYQDAVIVSP 284
Query: 173 DAGGAKRAAGLADRLDLNFALIHKER 198
DAGGAKRA +AD L+L+FALIHKER
Sbjct: 285 DAGGAKRATAIADALELSFALIHKER 310
Score = 73.6 bits (179), Expect = 4e-13
Identities = 37/100 (37%), Positives = 65/100 (65%), Gaps = 1/100 (1%)
Query: 1 MATNSIKLLAPDVHRNLAELVAKRLGLKLTNCKLKRDPSGEVSFSIGESVRDQDIFIVTQ 60
M+ ++I + D H L + + L + + +L + +GE + ++ ESVR++D++I+ Q
Sbjct: 1 MSMSNIVVFGGDSHPELVTKICENLDIHPSKVELGKFSNGETNIALRESVREKDVYII-Q 59
Query: 61 IGSGDVNDRVLELLIMINASKTASARRITAIIPNFPYARQ 100
G G VND ++LLI+I+A K+ASA R+TA++P Y+RQ
Sbjct: 60 SGCGQVNDTFMQLLILISACKSASASRVTAVMPYLCYSRQ 99
>Hs20542182 [FE] KOG1448 Ribose-phosphate pyrophosphokinase
Length = 271
Score = 67.8 bits (164), Expect = 2e-11
Identities = 45/132 (34%), Positives = 71/132 (53%), Gaps = 6/132 (4%)
Query: 17 LAELVAKRLGLKLTNCKLKRDPSGEVSFSIGESVRDQDIFIVTQIGSGDVNDRVLELLIM 76
LA+ V KR GL+L K+ + EVS GE +RDQ +++ +I ND L L M
Sbjct: 55 LAQKVVKRWGLELGKVVTKKFSNQEVSIVSGERMRDQAAYVIVKI-----ND-TLTSLAM 108
Query: 77 INASKTASARRITAIIPNFPYARQDRKDKSRAPITAKLMADMLTTAGCDHVITMDLHASQ 136
N K + + A++ PYA+QD+KDKS ++AKL+A++ + AG +
Sbjct: 109 TNVCKATWSSGMKAVLSCSPYAQQDQKDKSHPAVSAKLVANVFSVAGRSVGVDRMFLVGD 168
Query: 137 IQGFFDVPVDNL 148
I+ + V VD++
Sbjct: 169 IKDWVAVLVDDI 180
>At2g42910 [FE] KOG1448 Ribose-phosphate pyrophosphokinase
Length = 337
Score = 60.5 bits (145), Expect = 3e-09
Identities = 62/265 (23%), Positives = 117/265 (43%), Gaps = 18/265 (6%)
Query: 12 DVHRNLAELVAKRLGLKLTNCKLKRDPSGEVSFSIGESVRDQDIFIVTQIGSGDVNDRVL 71
++ RN+A + + L+ N + D + + +R Q + + S V +
Sbjct: 38 ELARNIAA-ESDHITLQSINWRSFADGFPNLFINNAHDIRGQHVAFLASFSSPAVIFEQI 96
Query: 72 ELLIMINASKTASARRITAIIPNFPYARQDRKDKSRAPITAKLMADMLTT-----AGCDH 126
++ ++ AS T ++P FP +R ++ TA MA +++ G
Sbjct: 97 SVIYLLPRLFVAS---FTLVLPFFPTGSFERMEEEGDVATAFTMARIVSNIPISRGGPTS 153
Query: 127 VITMDLHASQIQGFFDVPVDNLYAE--PSVVRYIKENVNFKEAIIISPDAGGAKRAAGLA 184
V+ D+HA Q + +F V L+ P + + +++ ++ I+ PD G KR L
Sbjct: 154 VVIYDIHALQERFYFADQVLPLFETGIPLLTKRLQQLPETEKVIVAFPDDGAWKRFHKLL 213
Query: 185 DRLDLNFALIHKERARANEVSRMVLVGDVSDKIC--IIVDDMADTCGTLAKAAEVLLENK 242
D ++ + + R + R+V + + + C +IVDD+ + GTL + +VL +
Sbjct: 214 D----HYPTVVCTKVREGD-KRIVRLKEGNPAGCHVVIVDDLVQSGGTLIECQKVLAAHG 268
Query: 243 AKSVIAIVTHGILSGKAIENINHSK 267
A V A VTHG+ + E H K
Sbjct: 269 AVKVSAYVTHGVFPKSSWERFTHKK 293
>At1g10700 [FE] KOG1448 Ribose-phosphate pyrophosphokinase
Length = 411
Score = 59.7 bits (143), Expect = 6e-09
Identities = 68/269 (25%), Positives = 114/269 (42%), Gaps = 28/269 (10%)
Query: 2 ATNSIKLLAPDVHRNLAE-LVAKRLGLKLTNCKLKRDPSGEVSFSI--GESVRDQDIFIV 58
++ + L D R+LAE +VAK ++L + K+ G + I + +R Q + +
Sbjct: 97 SSKRVCLFHSDETRDLAERIVAKSDCIELRSINWKKFDDGFPNLFIQNAQGIRGQHVAFL 156
Query: 59 TQIGSGDVNDRVLELLIMINASKTASARRITAIIPNFPYARQDRKDKSRAPITAKLMADM 118
S V + E L +I A T ++P FP +R + TA +A +
Sbjct: 157 ASFSSPAV---IFEQLSVIYALPKLFVSSFTLVLPFFPTGTSERMEDEGDVATAFTLARI 213
Query: 119 LTT-----AGCDHVITMDLHASQIQGFFDVPVDNLYAE--PSVVRYIKENVNFKEAIIIS 171
L+ G ++T D+HA Q + +F + + P + ++ + I
Sbjct: 214 LSNIPTSRGGPTSLVTFDIHALQERFYFGDTILPCFESGIPLLKSRLQSLPDSDNISIAF 273
Query: 172 PDAGGAKRAAGLADRLDLNFALIHKERARANEV----SRMVLV--GDVSDKICIIVDDMA 225
PD G KR + L H N+V R+V + GD + +IVDD+
Sbjct: 274 PDDGAWKR---------FHKQLQHYPTIVCNKVRMGDKRIVRIKEGDAEGRHVVIVDDLV 324
Query: 226 DTCGTLAKAAEVLLENKAKSVIAIVTHGI 254
+ GTL + +VL + A + A VTHGI
Sbjct: 325 QSGGTLIECQKVLAAHGAAKISAYVTHGI 353
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.320 0.136 0.378
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,660,331
Number of Sequences: 60738
Number of extensions: 629707
Number of successful extensions: 1591
Number of sequences better than 1.0e-05: 26
Number of HSP's better than 0.0 without gapping: 23
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 1495
Number of HSP's gapped (non-prelim): 35
length of query: 320
length of database: 30,389,216
effective HSP length: 106
effective length of query: 214
effective length of database: 23,950,988
effective search space: 5125511432
effective search space used: 5125511432
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)