ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI6927 good R KOG0504 General function prediction only FOG: Ankyrin repeat
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI6927 2412271 2411264 -336
(336 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YMR068w [R] KOG0504 FOG: Ankyrin repeat 204 1e-52
7300995 [T] KOG0507 CASK-interacting adaptor protein (caskin) an... 74 4e-13
7295202 [M] KOG4177 Ankyrin 72 9e-13
Hs4502093 [M] KOG4177 Ankyrin 71 3e-12
Hs10947056 [M] KOG4177 Ankyrin 71 3e-12
Hs22064845 [T] KOG0192 Tyrosine kinase specific for activated (G... 70 3e-12
Hs14731279 [R] KOG0504 FOG: Ankyrin repeat 70 4e-12
CE06705 [M] KOG4177 Ankyrin 69 7e-12
CE06704 [M] KOG4177 Ankyrin 69 7e-12
CE06703 [M] KOG4177 Ankyrin 69 7e-12
CE06702 [M] KOG4177 Ankyrin 69 7e-12
Hs18252778 [R] KOG0504 FOG: Ankyrin repeat 69 1e-11
Hs20538133 [R] KOG0504 FOG: Ankyrin repeat 68 2e-11
Hs10947054 [M] KOG4177 Ankyrin 68 2e-11
Hs10947052 [M] KOG4177 Ankyrin 68 2e-11
Hs10947042 [M] KOG4177 Ankyrin 68 2e-11
Hs10947040 [M] KOG4177 Ankyrin 68 2e-11
Hs10947038 [M] KOG4177 Ankyrin 68 2e-11
Hs10947036 [M] KOG4177 Ankyrin 68 2e-11
Hs7705831 [R] KOG0504 FOG: Ankyrin repeat 66 6e-11
Hs7705748 [T] KOG0192 Tyrosine kinase specific for activated (GT... 66 6e-11
Hs10190676_2 [R] KOG0504 FOG: Ankyrin repeat 66 6e-11
Hs7662406 [R] KOG0504 FOG: Ankyrin repeat 66 8e-11
7301236 [T] KOG0507 CASK-interacting adaptor protein (caskin) an... 66 8e-11
Hs21264330_2 [R] KOG0504 FOG: Ankyrin repeat 65 1e-10
Hs18254474 [R] KOG0504 FOG: Ankyrin repeat 64 2e-10
Hs13899329 [R] KOG0504 FOG: Ankyrin repeat 64 3e-10
7304338 [M] KOG4177 Ankyrin 64 3e-10
Hs8923104 [R] KOG0504 FOG: Ankyrin repeat 64 4e-10
Hs14149803 [U] KOG2319 Vacuolar assembly/sorting protein VPS9 64 4e-10
Hs13376003 [M] KOG4177 Ankyrin 64 4e-10
7301359 [M] KOG4177 Ankyrin 63 7e-10
Hs4885087 [R] KOG0504 FOG: Ankyrin repeat 62 9e-10
Hs20472035 [R] KOG0504 FOG: Ankyrin repeat 61 2e-09
CE26238_1 [M] KOG4177 Ankyrin 61 3e-09
Hs13376842 [M] KOG4177 Ankyrin 60 3e-09
Hs4507613 [M] KOG4177 Ankyrin 60 4e-09
7294199_2 [R] KOG0504 FOG: Ankyrin repeat 60 4e-09
Hs7656961 [R] KOG0504 FOG: Ankyrin repeat 60 6e-09
At5g60070 [R] KOG0504 FOG: Ankyrin repeat 59 8e-09
Hs7706377 [R] KOG0504 FOG: Ankyrin repeat 58 2e-08
Hs6601590 [R] KOG0510 Ankyrin repeat protein 58 2e-08
Hs18254470 [R] KOG0504 FOG: Ankyrin repeat 58 2e-08
7298956 [R] KOG0510 Ankyrin repeat protein 58 2e-08
Hs10835177_2 [R] KOG0504 FOG: Ankyrin repeat 58 2e-08
At5g13530_3 [R] KOG0504 FOG: Ankyrin repeat 58 2e-08
Hs16159328 [R] KOG0504 FOG: Ankyrin repeat 57 3e-08
7291960_1 [R] KOG0504 FOG: Ankyrin repeat 57 3e-08
Hs4506499 [R] KOG0502 Integral membrane ankyrin-repeat protein K... 57 4e-08
Hs20556512 [T] KOG0507 CASK-interacting adaptor protein (caskin)... 56 6e-08
Hs18079216 [T] KOG0507 CASK-interacting adaptor protein (caskin)... 56 6e-08
Hs17441942 [R] KOG0504 FOG: Ankyrin repeat 56 6e-08
CE20486 [OT] KOG0505 Myosin phosphatase regulatory subunit 56 6e-08
At5g40160 [R] KOG0504 FOG: Ankyrin repeat 56 6e-08
7298524_2 [R] KOG0504 FOG: Ankyrin repeat 56 6e-08
SPAC2F7.10 [R] KOG0509 Ankyrin repeat and DHHC-type Zn-finger do... 56 8e-08
Hs4506217 [O] KOG4412 26S proteasome regulatory complex subunit ... 56 8e-08
Hs18426879 [BK] KOG1082 Histone H3 (Lys9) methyltransferase SUV3... 56 8e-08
Hs18375637 [BK] KOG1082 Histone H3 (Lys9) methyltransferase SUV3... 56 8e-08
7296976 [M] KOG4177 Ankyrin 56 8e-08
7298294 [R] KOG0504 FOG: Ankyrin repeat 55 1e-07
7294194 [OT] KOG0505 Myosin phosphatase regulatory subunit 55 1e-07
Hs11968152_1 [R] KOG0504 FOG: Ankyrin repeat 55 1e-07
CE04223 [R] KOG0504 FOG: Ankyrin repeat 55 2e-07
At5g02620 [R] KOG0504 FOG: Ankyrin repeat 55 2e-07
At1g07710 [R] KOG0504 FOG: Ankyrin repeat 55 2e-07
7297920 [R] KOG0509 Ankyrin repeat and DHHC-type Zn-finger domai... 55 2e-07
Hs4557349_2 [R] KOG0504 FOG: Ankyrin repeat 55 2e-07
Hs22051302 [R] KOG0514 Ankyrin repeat protein 54 2e-07
Hs4505319 [OT] KOG0505 Myosin phosphatase regulatory subunit 54 3e-07
Hs22055239 [R] KOG0504 FOG: Ankyrin repeat 54 3e-07
Hs21314722 [BK] KOG1082 Histone H3 (Lys9) methyltransferase SUV3... 54 3e-07
Hs18640738 [R] KOG0504 FOG: Ankyrin repeat 54 3e-07
Hs14195601 [OT] KOG0505 Myosin phosphatase regulatory subunit 54 3e-07
7298193 [K] KOG0512 Fetal globin-inducing factor (contains ankyr... 54 3e-07
Hs22062923 [R] KOG0504 FOG: Ankyrin repeat 54 4e-07
Hs14149716 [OT] KOG0505 Myosin phosphatase regulatory subunit 54 4e-07
Hs13375989 [R] KOG0504 FOG: Ankyrin repeat 54 4e-07
Hs12746412 [R] KOG0502 Integral membrane ankyrin-repeat protein ... 54 4e-07
CE27723 [T] KOG0192 Tyrosine kinase specific for activated (GTP-... 54 4e-07
7304095 [T] KOG0521 Putative GTPase activating proteins (GAPs) 54 4e-07
Hs4505317 [OT] KOG0505 Myosin phosphatase regulatory subunit 53 5e-07
Hs21450703 [R] KOG0504 FOG: Ankyrin repeat 53 5e-07
Hs22056002 [Z] KOG0676 Actin and related proteins 53 7e-07
Hs22048285 [Z] KOG0676 Actin and related proteins 52 9e-07
Hs19924156 [R] KOG0502 Integral membrane ankyrin-repeat protein ... 52 9e-07
Hs18254476 [R] KOG0504 FOG: Ankyrin repeat 52 9e-07
At1g05640 [R] KOG0504 FOG: Ankyrin repeat 52 9e-07
7295892 [M] KOG4177 Ankyrin 52 1e-06
Hs22059561 [R] KOG0504 FOG: Ankyrin repeat 52 2e-06
Hs22051029 [T] KOG0705 GTPase-activating protein Centaurin gamma... 52 2e-06
At2g17390 [R] KOG0504 FOG: Ankyrin repeat 52 2e-06
Hs7662484 [T] KOG0705 GTPase-activating protein Centaurin gamma ... 51 2e-06
Hs14150037 [R] KOG0504 FOG: Ankyrin repeat 51 2e-06
At2g26650 [PT] KOG0498 K+-channel ERG and related proteins conta... 51 2e-06
At2g03430 [O] KOG4412 26S proteasome regulatory complex subunit ... 51 2e-06
7301689 [R] KOG0504 FOG: Ankyrin repeat 51 2e-06
7295029 [R] KOG0510 Ankyrin repeat protein 51 2e-06
7291939 [R] KOG0510 Ankyrin repeat protein 51 2e-06
Hs7705278_2 [R] KOG0504 FOG: Ankyrin repeat 51 2e-06
Hs19923223_2 [R] KOG0504 FOG: Ankyrin repeat 51 2e-06
Hs22053338 [T] KOG0705 GTPase-activating protein Centaurin gamma... 51 3e-06
Hs22051953 [T] KOG0705 GTPase-activating protein Centaurin gamma... 51 3e-06
Hs20547087 [T] KOG0705 GTPase-activating protein Centaurin gamma... 51 3e-06
Hs19263343 [T] KOG0705 GTPase-activating protein Centaurin gamma... 51 3e-06
Hs17485543 [R] KOG0504 FOG: Ankyrin repeat 51 3e-06
Hs20270347 [R] KOG0504 FOG: Ankyrin repeat 50 4e-06
Hs10092619 [R] KOG0504 FOG: Ankyrin repeat 50 4e-06
At4g35450 [R] KOG0504 FOG: Ankyrin repeat 50 4e-06
Hs7661962 [T] KOG0705 GTPase-activating protein Centaurin gamma ... 50 5e-06
Hs22051601 [R] KOG0514 Ankyrin repeat protein 50 5e-06
Hs20547911 [T] KOG0705 GTPase-activating protein Centaurin gamma... 50 5e-06
Hs20543681 [T] KOG0705 GTPase-activating protein Centaurin gamma... 50 5e-06
Hs14738291 [R] KOG0504 FOG: Ankyrin repeat 50 5e-06
7301132 [R] KOG0504 FOG: Ankyrin repeat 50 5e-06
Hs7657238 [R] KOG0504 FOG: Ankyrin repeat 50 6e-06
At2g01680 [R] KOG0504 FOG: Ankyrin repeat 50 6e-06
7299952 [R] KOG0508 Ankyrin repeat protein 50 6e-06
SPAC6C3.08 [O] KOG4412 26S proteasome regulatory complex subunit... 49 8e-06
Hs14742395 [R] KOG0514 Ankyrin repeat protein 49 8e-06
At2g31820 [R] KOG0504 FOG: Ankyrin repeat 49 8e-06
>YMR068w [R] KOG0504 FOG: Ankyrin repeat
Length = 426
Score = 204 bits (520), Expect = 1e-52
Identities = 115/246 (46%), Positives = 159/246 (63%), Gaps = 19/246 (7%)
Query: 1 MIPEPRIRLREAIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLI 60
M+ EP +RLREAI++G L +V+R+L+R PDLL NIDS NGWSSLHYA+++GRYLIC +LI
Sbjct: 1 MLKEPSVRLREAIIEGNLLIVKRLLRRNPDLLTNIDSENGWSSLHYASYHGRYLICVYLI 60
Query: 61 QLGHDATAMLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIAC 120
QLGHD ++KT+ G+TC+HLA+ KG EQT+HLLLQ F +N R + R APIHIAC
Sbjct: 61 QLGHDKHELIKTFKGNTCVHLALMKGHEQTLHLLLQQF-PRFINHRGENGR--APIHIAC 117
Query: 121 RSNHSRCLALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCGGATLADEQNQMG 180
+++ +CL+LL+ GAD+ + D G+T LHV +EYG+I C+ +LL G +L D G
Sbjct: 118 MNDYYQCLSLLIGVGADLWVMDTNGDTPLHVCLEYGSISCMKMLLNEGEVSLDDNVRDKG 177
Query: 181 -----IVAR--QVGNCDETIKKFDQFAAEIRK---GVSSGSSTVPIGTPDIAASKTFLGG 230
VA+ +VGN + K E++K + +G TP + A TF G
Sbjct: 178 NWKPIDVAQTFEVGNIYSKVLK------EVKKKGPPLGAGKKPSSFRTPILNAKATFEDG 231
Query: 231 NNGPLS 236
+ LS
Sbjct: 232 PSPVLS 237
>7300995 [T] KOG0507 CASK-interacting adaptor protein (caskin) and related
proteins with ankyrin repeats and SAM domain
Length = 1315
Score = 73.6 bits (179), Expect = 4e-13
Identities = 45/134 (33%), Positives = 71/134 (52%), Gaps = 5/134 (3%)
Query: 34 NIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHL 93
N+ + G+S+LH+A G I R L L H+A+ L G + +HLA G+ + V L
Sbjct: 43 NVQDSGGYSALHHACLNGHEDIVRLL--LAHEASPNLPDSRGSSPLHLAAWAGETEIVRL 100
Query: 94 LLQH-FLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVA 152
LL H + NL++ P+H A + H+ LALLL AD + + G T L +A
Sbjct: 101 LLTHPYRPASANLQTIEQE--TPLHCAAQHGHTGALALLLHHDADPNMRNSRGETPLDLA 158
Query: 153 MEYGAIQCLPILLQ 166
+YG +Q + +L++
Sbjct: 159 AQYGRLQAVQMLIR 172
>7295202 [M] KOG4177 Ankyrin
Length = 2443
Score = 72.4 bits (176), Expect = 9e-13
Identities = 47/151 (31%), Positives = 84/151 (55%), Gaps = 7/151 (4%)
Query: 17 KLGVVRRILKRWPDLLE-NIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDG 75
+ G + R+L+ + ++ N + NG ++LH A+ G + L++ G A T G
Sbjct: 20 RAGNLERVLEHLKNNIDINTSNANGLNALHLASKDGHIHVVSELLRRG--AIVDSATKKG 77
Query: 76 DTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCG 135
+T +H+A G E+ V LLL+H +N++S + + P+++A + NH + LLL G
Sbjct: 78 NTALHIASLAGQEEVVKLLLEH--NASVNVQSQNG--FTPLYMAAQENHDAVVRLLLSNG 133
Query: 136 ADVTLEDEEGNTGLHVAMEYGAIQCLPILLQ 166
A+ +L E+G T L VAM+ G + + +LL+
Sbjct: 134 ANQSLATEDGFTPLAVAMQQGHDKVVAVLLE 164
Score = 65.5 bits (158), Expect = 1e-10
Identities = 52/173 (30%), Positives = 80/173 (46%), Gaps = 11/173 (6%)
Query: 16 GKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDG 75
G + V + +L R D N + NG++ LH A R + L++ H A+ T G
Sbjct: 348 GHVRVAKLLLDRNADA--NARALNGFTPLHIACKKNRLKVVELLLR--HGASISATTESG 403
Query: 76 DTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCG 135
T +H+A G V LLQH + + R P+H+A R+N + + +LL+ G
Sbjct: 404 LTPLHVAAFMGCMNIVIYLLQHDASPDV----PTVRGETPLHLAARANQTDIIRILLRNG 459
Query: 136 ADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCGG---ATLADEQNQMGIVARQ 185
A V E T LH+A G + + +LLQ G AT D + I A++
Sbjct: 460 AQVDARAREQQTPLHIASRLGNVDIVMLLLQHGAQVDATTKDMYTALHIAAKE 512
Score = 63.2 bits (152), Expect = 5e-10
Identities = 46/148 (31%), Positives = 74/148 (49%), Gaps = 8/148 (5%)
Query: 9 LREAIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATA 68
L A + +L VV +L+ + +S G + LH AAF G I +L+Q HDA+
Sbjct: 374 LHIACKKNRLKVVELLLRHGASISATTES--GLTPLHVAAFMGCMNIVIYLLQ--HDASP 429
Query: 69 MLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCL 128
+ T G+T +HLA + +LL++ G + + + + P+HIA R + +
Sbjct: 430 DVPTVRGETPLHLAARANQTDIIRILLRN----GAQVDARAREQQTPLHIASRLGNVDIV 485
Query: 129 ALLLQCGADVTLEDEEGNTGLHVAMEYG 156
LLLQ GA V ++ T LH+A + G
Sbjct: 486 MLLLQHGAQVDATTKDMYTALHIAAKEG 513
Score = 61.6 bits (148), Expect = 2e-09
Identities = 41/132 (31%), Positives = 66/132 (49%), Gaps = 6/132 (4%)
Query: 34 NIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHL 93
++ S +G++ LH A+ YG I LIQ G D K + +H+A G V L
Sbjct: 199 DVTSKSGFTPLHIASHYGNQNIANLLIQKGADVNYSAK--HNISPLHVAAKWGKTNMVSL 256
Query: 94 LLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAM 153
LL E+G N+ + + P+H A RS H + + +LL+ GA ++ + + G LH+A
Sbjct: 257 LL----EKGGNIEAKTRDGLTPLHCAARSGHEQVVDMLLERGAPISAKTKNGLAPLHMAA 312
Query: 154 EYGAIQCLPILL 165
+ + ILL
Sbjct: 313 QGEHVDAARILL 324
Score = 58.9 bits (141), Expect = 1e-08
Identities = 42/145 (28%), Positives = 67/145 (45%), Gaps = 13/145 (8%)
Query: 44 LHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHLLLQHF----- 98
LH A+ G I L+Q H A T D T +H+A +G ++ L+ +
Sbjct: 473 LHIASRLGNVDIVMLLLQ--HGAQVDATTKDMYTALHIAAKEGQDEVKDLIAKKITDHID 530
Query: 99 ------LEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVA 152
+E G L +++ + + P+H+ + H + LLLQ ADV + + G T LHVA
Sbjct: 531 TVAAVLIENGAALDAATKKGFTPLHLTAKYGHIKVAQLLLQKEADVDAQGKNGVTPLHVA 590
Query: 153 MEYGAIQCLPILLQCGGATLADEQN 177
Y Q +LL+ G + A +N
Sbjct: 591 CHYNNQQVALLLLEKGASPHATAKN 615
Score = 57.4 bits (137), Expect = 3e-08
Identities = 45/147 (30%), Positives = 72/147 (48%), Gaps = 8/147 (5%)
Query: 20 VVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCI 79
VV +L+R + + + NG + LH AA G ++ ++ L H A T D T +
Sbjct: 286 VVDMLLERGAPI--SAKTKNGLAPLHMAA-QGEHVDAARIL-LYHRAPVDEVTVDYLTAL 341
Query: 80 HLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVT 139
H+A G + LLL + + + + + P+HIAC+ N + + LLL+ GA ++
Sbjct: 342 HVAAHCGHVRVAKLLL----DRNADANARALNGFTPLHIACKKNRLKVVELLLRHGASIS 397
Query: 140 LEDEEGNTGLHVAMEYGAIQCLPILLQ 166
E G T LHVA G + + LLQ
Sbjct: 398 ATTESGLTPLHVAAFMGCMNIVIYLLQ 424
Score = 56.2 bits (134), Expect = 6e-08
Identities = 38/127 (29%), Positives = 63/127 (48%), Gaps = 6/127 (4%)
Query: 40 GWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHLLLQHFL 99
G++ LH A YG + + L+Q D A K +G T +H+A ++Q LLL
Sbjct: 550 GFTPLHLTAKYGHIKVAQLLLQKEADVDAQGK--NGVTPLHVACHYNNQQVALLLL---- 603
Query: 100 EEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAMEYGAIQ 159
E+G + +++ P+HIA R N LL+ GA E + G T LH++ + G +
Sbjct: 604 EKGASPHATAKNGHTPLHIAARKNQMDIATTLLEYGALANAESKAGFTPLHLSSQEGHAE 663
Query: 160 CLPILLQ 166
+L++
Sbjct: 664 ISNLLIE 670
Score = 51.6 bits (122), Expect = 2e-06
Identities = 31/116 (26%), Positives = 60/116 (51%), Gaps = 4/116 (3%)
Query: 62 LGHDATAMLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACR 121
L +D + + G T +H+A G++ +LL+Q +G ++ S+ +P+H+A +
Sbjct: 192 LDNDHNPDVTSKSGFTPLHIASHYGNQNIANLLIQ----KGADVNYSAKHNISPLHVAAK 247
Query: 122 SNHSRCLALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCGGATLADEQN 177
+ ++LLL+ G ++ + +G T LH A G Q + +LL+ G A +N
Sbjct: 248 WGKTNMVSLLLEKGGNIEAKTRDGLTPLHCAARSGHEQVVDMLLERGAPISAKTKN 303
Score = 51.6 bits (122), Expect = 2e-06
Identities = 44/160 (27%), Positives = 76/160 (47%), Gaps = 12/160 (7%)
Query: 9 LREAIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATA 68
L A + G+ VV+ +L+ + N+ S NG++ L+ AA + R L+ G A
Sbjct: 81 LHIASLAGQEEVVKLLLEHNASV--NVQSQNGFTPLYMAAQENHDAVVRLLLSNG--ANQ 136
Query: 69 MLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCL 128
L T DG T + +A+ +G ++ V +LL+ + L + +HIA + + +
Sbjct: 137 SLATEDGFTPLAVAMQQGHDKVVAVLLESDTRGKVRLPA--------LHIAAKKDDVKAA 188
Query: 129 ALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCG 168
LLL + + + G T LH+A YG +L+Q G
Sbjct: 189 TLLLDNDHNPDVTSKSGFTPLHIASHYGNQNIANLLIQKG 228
>Hs4502093 [M] KOG4177 Ankyrin
Length = 1088
Score = 70.9 bits (172), Expect = 3e-12
Identities = 45/155 (29%), Positives = 78/155 (50%), Gaps = 8/155 (5%)
Query: 12 AIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLK 71
A G + +V +++ N + G ++LH AA G+ + R+L+Q G A K
Sbjct: 61 AAFMGHVNIVSQLMHHGAS--PNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAK 118
Query: 72 TYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALL 131
D T +H++ G V LLQ +G + +++ + P+H++ R H A L
Sbjct: 119 --DDQTPLHISARLGKADIVQQLLQ----QGASPNAATTSGYTPLHLSAREGHEDVAAFL 172
Query: 132 LQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQ 166
L GA +++ ++G T LHVA +YG ++ +LLQ
Sbjct: 173 LDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQ 207
Score = 62.0 bits (149), Expect = 1e-09
Identities = 44/139 (31%), Positives = 65/139 (46%), Gaps = 6/139 (4%)
Query: 39 NGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHLLLQHF 98
NG++ LH AA + I L++ G DA A+ T G +HLA +G V LLL
Sbjct: 251 NGYTPLHIAAKKNQMDIATTLLEYGADANAV--TRQGIASVHLAAQEGHVDMVSLLLGR- 307
Query: 99 LEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAMEYGAI 158
N+ S+ P+H+A + + +L+ GA V + + G T LHV YG I
Sbjct: 308 ---NANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNI 364
Query: 159 QCLPILLQCGGATLADEQN 177
+ + LLQ A +N
Sbjct: 365 KIVNFLLQHSAKVNAKTKN 383
Score = 59.3 bits (142), Expect = 8e-09
Identities = 40/132 (30%), Positives = 67/132 (50%), Gaps = 6/132 (4%)
Query: 34 NIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHL 93
+I + G++ LH AA YG+ + L+Q A K+ G T +H+A D Q V L
Sbjct: 180 SITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKS--GLTPLHVA-AHYDNQKVAL 236
Query: 94 LLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAM 153
LL L++G + +++ + P+HIA + N LL+ GAD +G +H+A
Sbjct: 237 LL---LDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAA 293
Query: 154 EYGAIQCLPILL 165
+ G + + +LL
Sbjct: 294 QEGHVDMVSLLL 305
Score = 56.2 bits (134), Expect = 6e-08
Identities = 39/137 (28%), Positives = 64/137 (46%), Gaps = 6/137 (4%)
Query: 34 NIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHL 93
N + NG++ LH A R + L++ H A+ T G T IH+A G V
Sbjct: 15 NAKALNGFTPLHIACKKNRIKVMELLLK--HGASIQAVTESGLTPIHVAAFMGHVNIVSQ 72
Query: 94 LLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAM 153
L+ H G + +++ R +H+A RS + + L+Q GA V + ++ T LH++
Sbjct: 73 LMHH----GASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISA 128
Query: 154 EYGAIQCLPILLQCGGA 170
G + LLQ G +
Sbjct: 129 RLGKADIVQQLLQQGAS 145
Score = 55.5 bits (132), Expect = 1e-07
Identities = 48/179 (26%), Positives = 84/179 (46%), Gaps = 14/179 (7%)
Query: 16 GKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDG 75
GK +V+++L++ N +T+G++ LH +A G + L L H A+ + T G
Sbjct: 131 GKADIVQQLLQQGAS--PNAATTSGYTPLHLSAREGHEDVAAFL--LDHGASLSITTKKG 186
Query: 76 DTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCG 135
T +H+A G + +LLLQ + + ++ P+H+A ++ + LLL G
Sbjct: 187 FTPLHVAAKYGKLEVANLLLQ----KSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQG 242
Query: 136 ADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCGGATLADEQNQMGI----VARQVGNCD 190
A + G T LH+A + + LL+ G A+ + GI +A Q G+ D
Sbjct: 243 ASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGAD--ANAVTRQGIASVHLAAQEGHVD 299
Score = 54.7 bits (130), Expect = 2e-07
Identities = 41/134 (30%), Positives = 61/134 (44%), Gaps = 6/134 (4%)
Query: 44 LHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGL 103
LH +A G+ I + L+Q G A T G T +HL+ +G E LL H G
Sbjct: 124 LHISARLGKADIVQQLLQQGASPNAA--TTSGYTPLHLSAREGHEDVAAFLLDH----GA 177
Query: 104 NLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPI 163
+L ++ + + P+H+A + LLLQ A + G T LHVA Y + +
Sbjct: 178 SLSITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALL 237
Query: 164 LLQCGGATLADEQN 177
LL G + A +N
Sbjct: 238 LLDQGASPHAAAKN 251
Score = 53.9 bits (128), Expect = 3e-07
Identities = 46/169 (27%), Positives = 77/169 (45%), Gaps = 13/169 (7%)
Query: 62 LGHDATAMLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACR 121
L A K +G T +H+A K + + LLL+H G ++++ + PIH+A
Sbjct: 8 LDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKH----GASIQAVTESGLTPIHVAAF 63
Query: 122 SNHSRCLALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCGG---ATLADEQNQ 178
H ++ L+ GA + G T LH+A G + + L+Q G A D+Q
Sbjct: 64 MGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTP 123
Query: 179 MGIVARQVGNCDETIKKFDQFAAEIRKGVSSGSSTVPI----GTPDIAA 223
+ I AR +G D +++ Q A +SG + + + G D+AA
Sbjct: 124 LHISAR-LGKAD-IVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAA 170
Score = 52.0 bits (123), Expect = 1e-06
Identities = 41/153 (26%), Positives = 69/153 (44%), Gaps = 8/153 (5%)
Query: 12 AIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLK 71
A +G + +V +L R ++ N+ + +G + LH AA R + L+ G A K
Sbjct: 292 AAQEGHVDMVSLLLGRNANV--NLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTK 349
Query: 72 TYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALL 131
G T +H+ G+ + V+ LLQH + + + + P+H A + H+ + +L
Sbjct: 350 M--GYTPLHVGCHYGNIKIVNFLLQH----SAKVNAKTKNGYTPLHQAAQQGHTHIINVL 403
Query: 132 LQCGADVTLEDEEGNTGLHVAMEYGAIQCLPIL 164
LQ A GNT L +A G I + L
Sbjct: 404 LQNNASPNELTVNGNTALGIARRLGYISVVDTL 436
>Hs10947056 [M] KOG4177 Ankyrin
Length = 4377
Score = 70.9 bits (172), Expect = 3e-12
Identities = 45/155 (29%), Positives = 78/155 (50%), Gaps = 8/155 (5%)
Query: 12 AIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLK 71
A G + +V +++ N + G ++LH AA G+ + R+L+Q G A K
Sbjct: 440 AAFMGHVNIVSQLMHHGAS--PNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAK 497
Query: 72 TYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALL 131
D T +H++ G V LLQ +G + +++ + P+H++ R H A L
Sbjct: 498 --DDQTPLHISARLGKADIVQQLLQ----QGASPNAATTSGYTPLHLSAREGHEDVAAFL 551
Query: 132 LQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQ 166
L GA +++ ++G T LHVA +YG ++ +LLQ
Sbjct: 552 LDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQ 586
Score = 66.6 bits (161), Expect = 5e-11
Identities = 41/133 (30%), Positives = 70/133 (51%), Gaps = 6/133 (4%)
Query: 34 NIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHL 93
NI + NG ++LH A+ G + L+Q +A T G+T +H+A G + V +
Sbjct: 68 NICNQNGLNALHLASKEGHVEVVSELLQ--REANVDAATKKGNTALHIASLAGQAEVVKV 125
Query: 94 LLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAM 153
L+ + G N+ + S + P+++A + NH + LL GA +L E+G T L VA+
Sbjct: 126 LVTN----GANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVAL 181
Query: 154 EYGAIQCLPILLQ 166
+ G Q + +LL+
Sbjct: 182 QQGHDQVVSLLLE 194
Score = 64.7 bits (156), Expect = 2e-10
Identities = 59/205 (28%), Positives = 100/205 (48%), Gaps = 17/205 (8%)
Query: 9 LREAIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATA 68
L A + G+ VV+ ++ ++ N S NG++ L+ AA + + L+ G A+
Sbjct: 111 LHIASLAGQAEVVKVLVTNGANV--NAQSQNGFTPLYMAAQENHLEVVKFLLDNG--ASQ 166
Query: 69 MLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCL 128
L T DG T + +A+ +G +Q V LLL++ + + L + +HIA R + ++
Sbjct: 167 SLATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPA--------LHIAARKDDTKAA 218
Query: 129 ALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCGGATLADEQNQMG--IVARQV 186
ALLLQ + +E + G T LH+A YG I +LL A +N + VA +
Sbjct: 219 ALLLQNDNNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKR 278
Query: 187 GNCDETIKKFDQFA---AEIRKGVS 208
GN + D+ A A+ R G++
Sbjct: 279 GNANMVKLLLDRGAKIDAKTRDGLT 303
Score = 62.0 bits (149), Expect = 1e-09
Identities = 44/139 (31%), Positives = 65/139 (46%), Gaps = 6/139 (4%)
Query: 39 NGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHLLLQHF 98
NG++ LH AA + I L++ G DA A+ T G +HLA +G V LLL
Sbjct: 630 NGYTPLHIAAKKNQMDIATTLLEYGADANAV--TRQGIASVHLAAQEGHVDMVSLLLGR- 686
Query: 99 LEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAMEYGAI 158
N+ S+ P+H+A + + +L+ GA V + + G T LHV YG I
Sbjct: 687 ---NANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNI 743
Query: 159 QCLPILLQCGGATLADEQN 177
+ + LLQ A +N
Sbjct: 744 KIVNFLLQHSAKVNAKTKN 762
Score = 59.3 bits (142), Expect = 8e-09
Identities = 40/132 (30%), Positives = 67/132 (50%), Gaps = 6/132 (4%)
Query: 34 NIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHL 93
+I + G++ LH AA YG+ + L+Q A K+ G T +H+A D Q V L
Sbjct: 559 SITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKS--GLTPLHVA-AHYDNQKVAL 615
Query: 94 LLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAM 153
LL L++G + +++ + P+HIA + N LL+ GAD +G +H+A
Sbjct: 616 LL---LDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAA 672
Query: 154 EYGAIQCLPILL 165
+ G + + +LL
Sbjct: 673 QEGHVDMVSLLL 684
Score = 58.9 bits (141), Expect = 1e-08
Identities = 46/151 (30%), Positives = 72/151 (47%), Gaps = 8/151 (5%)
Query: 20 VVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCI 79
VV +L R +L + NG S LH A G +L C L+ L H+ T D T +
Sbjct: 316 VVEMLLDRAAPILSK--TKNGLSPLHMAT-QGDHLNCVQLL-LQHNVPVDDVTNDYLTAL 371
Query: 80 HLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVT 139
H+A G + +LL ++ N + + + P+HIAC+ N + + LLL+ GA +
Sbjct: 372 HVAAHCGHYKVAKVLL----DKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQ 427
Query: 140 LEDEEGNTGLHVAMEYGAIQCLPILLQCGGA 170
E G T +HVA G + + L+ G +
Sbjct: 428 AVTESGLTPIHVAAFMGHVNIVSQLMHHGAS 458
Score = 57.8 bits (138), Expect = 2e-08
Identities = 38/134 (28%), Positives = 69/134 (51%), Gaps = 8/134 (5%)
Query: 34 NIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGD-TCIHLAITKGDEQTVH 92
+++S +G++ LH AA YG + L+ + A A+ T D T +H+A +G+ V
Sbjct: 229 DVESKSGFTPLHIAAHYGNINVATLLL---NRAAAVDFTARNDITPLHVASKRGNANMVK 285
Query: 93 LLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVA 152
LLL + G + + + P+H RS H + + +LL A + + + G + LH+A
Sbjct: 286 LLL----DRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMA 341
Query: 153 MEYGAIQCLPILLQ 166
+ + C+ +LLQ
Sbjct: 342 TQGDHLNCVQLLLQ 355
Score = 56.2 bits (134), Expect = 6e-08
Identities = 39/137 (28%), Positives = 64/137 (46%), Gaps = 6/137 (4%)
Query: 34 NIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHL 93
N + NG++ LH A R + L++ H A+ T G T IH+A G V
Sbjct: 394 NAKALNGFTPLHIACKKNRIKVMELLLK--HGASIQAVTESGLTPIHVAAFMGHVNIVSQ 451
Query: 94 LLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAM 153
L+ H G + +++ R +H+A RS + + L+Q GA V + ++ T LH++
Sbjct: 452 LMHH----GASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISA 507
Query: 154 EYGAIQCLPILLQCGGA 170
G + LLQ G +
Sbjct: 508 RLGKADIVQQLLQQGAS 524
Score = 55.5 bits (132), Expect = 1e-07
Identities = 48/179 (26%), Positives = 84/179 (46%), Gaps = 14/179 (7%)
Query: 16 GKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDG 75
GK +V+++L++ N +T+G++ LH +A G + L L H A+ + T G
Sbjct: 510 GKADIVQQLLQQGAS--PNAATTSGYTPLHLSAREGHEDVAAFL--LDHGASLSITTKKG 565
Query: 76 DTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCG 135
T +H+A G + +LLLQ + + ++ P+H+A ++ + LLL G
Sbjct: 566 FTPLHVAAKYGKLEVANLLLQ----KSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQG 621
Query: 136 ADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCGGATLADEQNQMGI----VARQVGNCD 190
A + G T LH+A + + LL+ G A+ + GI +A Q G+ D
Sbjct: 622 ASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGAD--ANAVTRQGIASVHLAAQEGHVD 678
Score = 54.7 bits (130), Expect = 2e-07
Identities = 41/134 (30%), Positives = 61/134 (44%), Gaps = 6/134 (4%)
Query: 44 LHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGL 103
LH +A G+ I + L+Q G A T G T +HL+ +G E LL H G
Sbjct: 503 LHISARLGKADIVQQLLQQGASPNAA--TTSGYTPLHLSAREGHEDVAAFLLDH----GA 556
Query: 104 NLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPI 163
+L ++ + + P+H+A + LLLQ A + G T LHVA Y + +
Sbjct: 557 SLSITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALL 616
Query: 164 LLQCGGATLADEQN 177
LL G + A +N
Sbjct: 617 LLDQGASPHAAAKN 630
Score = 52.0 bits (123), Expect = 1e-06
Identities = 41/153 (26%), Positives = 69/153 (44%), Gaps = 8/153 (5%)
Query: 12 AIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLK 71
A +G + +V +L R ++ N+ + +G + LH AA R + L+ G A K
Sbjct: 671 AAQEGHVDMVSLLLGRNANV--NLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTK 728
Query: 72 TYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALL 131
G T +H+ G+ + V+ LLQH + + + + P+H A + H+ + +L
Sbjct: 729 M--GYTPLHVGCHYGNIKIVNFLLQH----SAKVNAKTKNGYTPLHQAAQQGHTHIINVL 782
Query: 132 LQCGADVTLEDEEGNTGLHVAMEYGAIQCLPIL 164
LQ A GNT L +A G I + L
Sbjct: 783 LQNNASPNELTVNGNTALGIARRLGYISVVDTL 815
>Hs22064845 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 722
Score = 70.5 bits (171), Expect = 3e-12
Identities = 49/165 (29%), Positives = 79/165 (47%), Gaps = 8/165 (4%)
Query: 13 IVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKT 72
+ QG + VR +L D+ + + +G++ L AA + +C L+ G DA + +
Sbjct: 346 VAQGSVEQVRLLLAHEVDV--DCQTASGYTPLLIAAQDQQPDLCALLLAHGADANRVDE- 402
Query: 73 YDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLL 132
DG +H A GD+ T LLL H G + + W P+H+A ++N LL+
Sbjct: 403 -DGWAPLHFAAQNGDDGTARLLLDH----GACVDAQEREGWTPLHLAAQNNFENVARLLV 457
Query: 133 QCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCGGATLADEQN 177
AD L + EG T LHVA +G + + +L G A ++N
Sbjct: 458 SRQADPNLHEAEGKTPLHVAAYFGHVSLVKLLTSQGAELDAQQRN 502
Score = 65.5 bits (158), Expect = 1e-10
Identities = 45/151 (29%), Positives = 71/151 (46%), Gaps = 31/151 (20%)
Query: 6 RIRLREAIVQGKLGVVRRILKRW--PDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLG 63
R L A+ +GK+ ++ +LK PD L+ +G+ LH AA G+YLIC+ L
Sbjct: 504 RTPLHLAVERGKVRAIQHLLKSGAVPDALDQ----SGYGPLHTAAARGKYLICKML---- 555
Query: 64 HDATAMLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSN 123
L++ + +HLL E N+ + A W P+H+A R
Sbjct: 556 -----------------LSLQGPPGEIIHLLA----ESHANMGALGAVNWTPLHLAARHG 594
Query: 124 HSRCLALLLQCGADVTLEDEEGNTGLHVAME 154
++ LLQCGAD ++ G T LH+A++
Sbjct: 595 EEAVVSALLQCGADPNAAEQSGWTPLHLAVQ 625
Score = 58.2 bits (139), Expect = 2e-08
Identities = 42/142 (29%), Positives = 65/142 (45%), Gaps = 6/142 (4%)
Query: 39 NGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHLLLQHF 98
+GW+ LH+AA G R L L H A + +G T +HLA E LL+
Sbjct: 403 DGWAPLHFAAQNGDDGTARLL--LDHGACVDAQEREGWTPLHLAAQNNFENVARLLVSRQ 460
Query: 99 LEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAMEYGAI 158
+ L+ A P+H+A H + LL GA++ + T LH+A+E G +
Sbjct: 461 ADPNLH----EAEGKTPLHVAAYFGHVSLVKLLTSQGAELDAQQRNLRTPLHLAVERGKV 516
Query: 159 QCLPILLQCGGATLADEQNQMG 180
+ + LL+ G A +Q+ G
Sbjct: 517 RAIQHLLKSGAVPDALDQSGYG 538
>Hs14731279 [R] KOG0504 FOG: Ankyrin repeat
Length = 743
Score = 70.1 bits (170), Expect = 4e-12
Identities = 66/251 (26%), Positives = 94/251 (37%), Gaps = 68/251 (27%)
Query: 4 EPRIRLREAIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLG 63
E R L A QG + VVR +L R D EN GW+ LH AAF G LIC LI+ G
Sbjct: 127 EGRTVLSIASAQGNVEVVRTLLDRGLD--ENHRDDAGWTPLHMAAFEGHRLICEALIEQG 184
Query: 64 ----------------------HDATAML---------KTYDGDTCIHLAITKGDEQTVH 92
+D +L + YDG + +A +G V
Sbjct: 185 ARTNEIDNDGRIPFILASQEGHYDCVQILLENKSNIDQRGYDGRNALRVAALEGHRDIVE 244
Query: 93 LLLQH-----------------------------FLEEGLNLRSSSARRWAPIHIACRSN 123
LL H FLE G N+ +S A +H++C
Sbjct: 245 LLFSHGADVNCKDADGRPTLYILALENQLTMAEYFLENGANVEASDAEGRTALHVSCWQG 304
Query: 124 HSRCLALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCGGATLADEQNQMG--- 180
H + +L+ ADV D E + L A G ++ + +L++ G + D G
Sbjct: 305 HMEMVQVLIAYHADVNAADNEKRSALQSAAWQGHVKVVQLLIEHG--AVVDHTCNQGATA 362
Query: 181 -IVARQVGNCD 190
+A Q G+ D
Sbjct: 363 LCIAAQEGHID 373
>CE06705 [M] KOG4177 Ankyrin
Length = 1815
Score = 69.3 bits (168), Expect = 7e-12
Identities = 47/151 (31%), Positives = 76/151 (50%), Gaps = 8/151 (5%)
Query: 16 GKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDG 75
G L V +L+ D+ N + NG +SLH A+ G + R LI+ A T G
Sbjct: 44 GDLEKVLELLRAGTDI--NTSNANGLNSLHLASKEGHSEVVRELIK--RQAQVDAATRKG 99
Query: 76 DTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCG 135
+T +H+A G V +L+ E G N+ S + P+++A + NH + LL+ G
Sbjct: 100 NTALHIASLAGQSLIVTILV----ENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHG 155
Query: 136 ADVTLEDEEGNTGLHVAMEYGAIQCLPILLQ 166
A+ L E+G T L VA++ G + + +LL+
Sbjct: 156 ANQALSTEDGFTPLAVALQQGHDRVVAVLLE 186
Score = 66.6 bits (161), Expect = 5e-11
Identities = 48/171 (28%), Positives = 86/171 (50%), Gaps = 8/171 (4%)
Query: 9 LREAIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATA 68
L A G + +V +L++ + ++++ G + LH AA + + R LI+ G A
Sbjct: 429 LHVAAFMGAINIVIYLLQQGAN--PDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDA 486
Query: 69 MLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCL 128
+ T +H+A G+ V LLLQ G N +++ ++P+HIA +
Sbjct: 487 QARELQ--TPLHIASRLGNTDIVILLLQ----AGANSNATTRDNYSPLHIAAKEGQEEVA 540
Query: 129 ALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCGGATLADEQNQM 179
+LL AD TL ++G T LH+A +YG ++ + +LL+ G + +NQ+
Sbjct: 541 GILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGTPVDIEGKNQV 591
Score = 55.5 bits (132), Expect = 1e-07
Identities = 42/160 (26%), Positives = 71/160 (44%), Gaps = 27/160 (16%)
Query: 34 NIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHL 93
N+ S NG++ L+ AA + ++L++ H A L T DG T + +A+ +G ++ V +
Sbjct: 126 NVQSVNGFTPLYMAAQENHEEVVKYLLK--HGANQALSTEDGFTPLAVALQQGHDRVVAV 183
Query: 94 LLQH-------------------------FLEEGLNLRSSSARRWAPIHIACRSNHSRCL 128
LL++ L+ N +S + P+HIA H
Sbjct: 184 LLENDSKGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFTPLHIAAHYGHENVG 243
Query: 129 ALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCG 168
LLL+ GA+V + + LHVA ++G +LL G
Sbjct: 244 QLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRG 283
Score = 55.1 bits (131), Expect = 1e-07
Identities = 45/173 (26%), Positives = 72/173 (41%), Gaps = 31/173 (17%)
Query: 34 NIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHL 93
N + + +S LH AA G+ + I L H+A L T G T +HLA G+ + V L
Sbjct: 518 NATTRDNYSPLHIAAKEGQEEVAG--ILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRL 575
Query: 94 LLQH-----------------------------FLEEGLNLRSSSARRWAPIHIACRSNH 124
LL+ LE G + ++++ + P+HIA + N
Sbjct: 576 LLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQ 635
Query: 125 SRCLALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCGGATLADEQN 177
+ LLQ AD + G T LH++ + G + +L++ G A N
Sbjct: 636 MEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGAKANN 688
Score = 55.1 bits (131), Expect = 1e-07
Identities = 42/147 (28%), Positives = 65/147 (43%), Gaps = 8/147 (5%)
Query: 34 NIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHL 93
N S G++ LH +A G I LI+ G D A K +G T +HL + +
Sbjct: 650 NAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGA--KANNGLTAMHLCAQEDHVPVAQI 707
Query: 94 LLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAM 153
L + G + S + + P+H+AC + L++ GADV + T LH A
Sbjct: 708 LYNN----GAEINSKTNAGYTPLHVACHFGQLNMVKFLVENGADVGEKTRASYTPLHQAA 763
Query: 154 EYGAIQCLPILLQCGGATLADEQNQMG 180
+ G C+ LL+ G + +EQ G
Sbjct: 764 QQGHNNCVRYLLENGAS--PNEQTATG 788
Score = 54.3 bits (129), Expect = 2e-07
Identities = 44/130 (33%), Positives = 60/130 (45%), Gaps = 6/130 (4%)
Query: 39 NGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHLLLQHF 98
NG + LH AA R L+ H A T D T +H+A G + LLL
Sbjct: 325 NGLAPLHMAAQGDHVDAARTLLY--HRAPVDDVTVDYLTPLHVAAHCGHVRVAKLLL--- 379
Query: 99 LEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAMEYGAI 158
+ + S + + P+HIAC+ N + + LLL+ A + E G T LHVA GAI
Sbjct: 380 -DRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAI 438
Query: 159 QCLPILLQCG 168
+ LLQ G
Sbjct: 439 NIVIYLLQQG 448
>CE06704 [M] KOG4177 Ankyrin
Length = 1867
Score = 69.3 bits (168), Expect = 7e-12
Identities = 47/151 (31%), Positives = 76/151 (50%), Gaps = 8/151 (5%)
Query: 16 GKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDG 75
G L V +L+ D+ N + NG +SLH A+ G + R LI+ A T G
Sbjct: 44 GDLEKVLELLRAGTDI--NTSNANGLNSLHLASKEGHSEVVRELIK--RQAQVDAATRKG 99
Query: 76 DTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCG 135
+T +H+A G V +L+ E G N+ S + P+++A + NH + LL+ G
Sbjct: 100 NTALHIASLAGQSLIVTILV----ENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHG 155
Query: 136 ADVTLEDEEGNTGLHVAMEYGAIQCLPILLQ 166
A+ L E+G T L VA++ G + + +LL+
Sbjct: 156 ANQALSTEDGFTPLAVALQQGHDRVVAVLLE 186
Score = 66.6 bits (161), Expect = 5e-11
Identities = 48/171 (28%), Positives = 86/171 (50%), Gaps = 8/171 (4%)
Query: 9 LREAIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATA 68
L A G + +V +L++ + ++++ G + LH AA + + R LI+ G A
Sbjct: 429 LHVAAFMGAINIVIYLLQQGAN--PDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDA 486
Query: 69 MLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCL 128
+ T +H+A G+ V LLLQ G N +++ ++P+HIA +
Sbjct: 487 QARELQ--TPLHIASRLGNTDIVILLLQ----AGANSNATTRDNYSPLHIAAKEGQEEVA 540
Query: 129 ALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCGGATLADEQNQM 179
+LL AD TL ++G T LH+A +YG ++ + +LL+ G + +NQ+
Sbjct: 541 GILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGTPVDIEGKNQV 591
Score = 55.5 bits (132), Expect = 1e-07
Identities = 42/160 (26%), Positives = 71/160 (44%), Gaps = 27/160 (16%)
Query: 34 NIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHL 93
N+ S NG++ L+ AA + ++L++ H A L T DG T + +A+ +G ++ V +
Sbjct: 126 NVQSVNGFTPLYMAAQENHEEVVKYLLK--HGANQALSTEDGFTPLAVALQQGHDRVVAV 183
Query: 94 LLQH-------------------------FLEEGLNLRSSSARRWAPIHIACRSNHSRCL 128
LL++ L+ N +S + P+HIA H
Sbjct: 184 LLENDSKGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFTPLHIAAHYGHENVG 243
Query: 129 ALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCG 168
LLL+ GA+V + + LHVA ++G +LL G
Sbjct: 244 QLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRG 283
Score = 55.1 bits (131), Expect = 1e-07
Identities = 45/173 (26%), Positives = 72/173 (41%), Gaps = 31/173 (17%)
Query: 34 NIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHL 93
N + + +S LH AA G+ + I L H+A L T G T +HLA G+ + V L
Sbjct: 518 NATTRDNYSPLHIAAKEGQEEVAG--ILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRL 575
Query: 94 LLQH-----------------------------FLEEGLNLRSSSARRWAPIHIACRSNH 124
LL+ LE G + ++++ + P+HIA + N
Sbjct: 576 LLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQ 635
Query: 125 SRCLALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCGGATLADEQN 177
+ LLQ AD + G T LH++ + G + +L++ G A N
Sbjct: 636 MEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGAKANN 688
Score = 55.1 bits (131), Expect = 1e-07
Identities = 42/147 (28%), Positives = 65/147 (43%), Gaps = 8/147 (5%)
Query: 34 NIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHL 93
N S G++ LH +A G I LI+ G D A K +G T +HL + +
Sbjct: 650 NAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGA--KANNGLTAMHLCAQEDHVPVAQI 707
Query: 94 LLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAM 153
L + G + S + + P+H+AC + L++ GADV + T LH A
Sbjct: 708 LYNN----GAEINSKTNAGYTPLHVACHFGQLNMVKFLVENGADVGEKTRASYTPLHQAA 763
Query: 154 EYGAIQCLPILLQCGGATLADEQNQMG 180
+ G C+ LL+ G + +EQ G
Sbjct: 764 QQGHNNCVRYLLENGAS--PNEQTATG 788
Score = 54.3 bits (129), Expect = 2e-07
Identities = 44/130 (33%), Positives = 60/130 (45%), Gaps = 6/130 (4%)
Query: 39 NGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHLLLQHF 98
NG + LH AA R L+ H A T D T +H+A G + LLL
Sbjct: 325 NGLAPLHMAAQGDHVDAARTLLY--HRAPVDDVTVDYLTPLHVAAHCGHVRVAKLLL--- 379
Query: 99 LEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAMEYGAI 158
+ + S + + P+HIAC+ N + + LLL+ A + E G T LHVA GAI
Sbjct: 380 -DRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAI 438
Query: 159 QCLPILLQCG 168
+ LLQ G
Sbjct: 439 NIVIYLLQQG 448
>CE06703 [M] KOG4177 Ankyrin
Length = 1809
Score = 69.3 bits (168), Expect = 7e-12
Identities = 47/151 (31%), Positives = 76/151 (50%), Gaps = 8/151 (5%)
Query: 16 GKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDG 75
G L V +L+ D+ N + NG +SLH A+ G + R LI+ A T G
Sbjct: 44 GDLEKVLELLRAGTDI--NTSNANGLNSLHLASKEGHSEVVRELIK--RQAQVDAATRKG 99
Query: 76 DTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCG 135
+T +H+A G V +L+ E G N+ S + P+++A + NH + LL+ G
Sbjct: 100 NTALHIASLAGQSLIVTILV----ENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHG 155
Query: 136 ADVTLEDEEGNTGLHVAMEYGAIQCLPILLQ 166
A+ L E+G T L VA++ G + + +LL+
Sbjct: 156 ANQALSTEDGFTPLAVALQQGHDRVVAVLLE 186
Score = 66.6 bits (161), Expect = 5e-11
Identities = 48/171 (28%), Positives = 86/171 (50%), Gaps = 8/171 (4%)
Query: 9 LREAIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATA 68
L A G + +V +L++ + ++++ G + LH AA + + R LI+ G A
Sbjct: 429 LHVAAFMGAINIVIYLLQQGAN--PDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDA 486
Query: 69 MLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCL 128
+ T +H+A G+ V LLLQ G N +++ ++P+HIA +
Sbjct: 487 QARELQ--TPLHIASRLGNTDIVILLLQ----AGANSNATTRDNYSPLHIAAKEGQEEVA 540
Query: 129 ALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCGGATLADEQNQM 179
+LL AD TL ++G T LH+A +YG ++ + +LL+ G + +NQ+
Sbjct: 541 GILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGTPVDIEGKNQV 591
Score = 55.5 bits (132), Expect = 1e-07
Identities = 42/160 (26%), Positives = 71/160 (44%), Gaps = 27/160 (16%)
Query: 34 NIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHL 93
N+ S NG++ L+ AA + ++L++ H A L T DG T + +A+ +G ++ V +
Sbjct: 126 NVQSVNGFTPLYMAAQENHEEVVKYLLK--HGANQALSTEDGFTPLAVALQQGHDRVVAV 183
Query: 94 LLQH-------------------------FLEEGLNLRSSSARRWAPIHIACRSNHSRCL 128
LL++ L+ N +S + P+HIA H
Sbjct: 184 LLENDSKGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFTPLHIAAHYGHENVG 243
Query: 129 ALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCG 168
LLL+ GA+V + + LHVA ++G +LL G
Sbjct: 244 QLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRG 283
Score = 55.1 bits (131), Expect = 1e-07
Identities = 45/173 (26%), Positives = 72/173 (41%), Gaps = 31/173 (17%)
Query: 34 NIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHL 93
N + + +S LH AA G+ + I L H+A L T G T +HLA G+ + V L
Sbjct: 518 NATTRDNYSPLHIAAKEGQEEVAG--ILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRL 575
Query: 94 LLQH-----------------------------FLEEGLNLRSSSARRWAPIHIACRSNH 124
LL+ LE G + ++++ + P+HIA + N
Sbjct: 576 LLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQ 635
Query: 125 SRCLALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCGGATLADEQN 177
+ LLQ AD + G T LH++ + G + +L++ G A N
Sbjct: 636 MEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGAKANN 688
Score = 55.1 bits (131), Expect = 1e-07
Identities = 42/147 (28%), Positives = 65/147 (43%), Gaps = 8/147 (5%)
Query: 34 NIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHL 93
N S G++ LH +A G I LI+ G D A K +G T +HL + +
Sbjct: 650 NAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGA--KANNGLTAMHLCAQEDHVPVAQI 707
Query: 94 LLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAM 153
L + G + S + + P+H+AC + L++ GADV + T LH A
Sbjct: 708 LYNN----GAEINSKTNAGYTPLHVACHFGQLNMVKFLVENGADVGEKTRASYTPLHQAA 763
Query: 154 EYGAIQCLPILLQCGGATLADEQNQMG 180
+ G C+ LL+ G + +EQ G
Sbjct: 764 QQGHNNCVRYLLENGAS--PNEQTATG 788
Score = 54.3 bits (129), Expect = 2e-07
Identities = 44/130 (33%), Positives = 60/130 (45%), Gaps = 6/130 (4%)
Query: 39 NGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHLLLQHF 98
NG + LH AA R L+ H A T D T +H+A G + LLL
Sbjct: 325 NGLAPLHMAAQGDHVDAARTLLY--HRAPVDDVTVDYLTPLHVAAHCGHVRVAKLLL--- 379
Query: 99 LEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAMEYGAI 158
+ + S + + P+HIAC+ N + + LLL+ A + E G T LHVA GAI
Sbjct: 380 -DRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAI 438
Query: 159 QCLPILLQCG 168
+ LLQ G
Sbjct: 439 NIVIYLLQQG 448
>CE06702 [M] KOG4177 Ankyrin
Length = 2039
Score = 69.3 bits (168), Expect = 7e-12
Identities = 47/151 (31%), Positives = 76/151 (50%), Gaps = 8/151 (5%)
Query: 16 GKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDG 75
G L V +L+ D+ N + NG +SLH A+ G + R LI+ A T G
Sbjct: 44 GDLEKVLELLRAGTDI--NTSNANGLNSLHLASKEGHSEVVRELIK--RQAQVDAATRKG 99
Query: 76 DTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCG 135
+T +H+A G V +L+ E G N+ S + P+++A + NH + LL+ G
Sbjct: 100 NTALHIASLAGQSLIVTILV----ENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHG 155
Query: 136 ADVTLEDEEGNTGLHVAMEYGAIQCLPILLQ 166
A+ L E+G T L VA++ G + + +LL+
Sbjct: 156 ANQALSTEDGFTPLAVALQQGHDRVVAVLLE 186
Score = 66.6 bits (161), Expect = 5e-11
Identities = 48/171 (28%), Positives = 86/171 (50%), Gaps = 8/171 (4%)
Query: 9 LREAIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATA 68
L A G + +V +L++ + ++++ G + LH AA + + R LI+ G A
Sbjct: 429 LHVAAFMGAINIVIYLLQQGAN--PDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDA 486
Query: 69 MLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCL 128
+ T +H+A G+ V LLLQ G N +++ ++P+HIA +
Sbjct: 487 QARELQ--TPLHIASRLGNTDIVILLLQ----AGANSNATTRDNYSPLHIAAKEGQEEVA 540
Query: 129 ALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCGGATLADEQNQM 179
+LL AD TL ++G T LH+A +YG ++ + +LL+ G + +NQ+
Sbjct: 541 GILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGTPVDIEGKNQV 591
Score = 55.5 bits (132), Expect = 1e-07
Identities = 42/160 (26%), Positives = 71/160 (44%), Gaps = 27/160 (16%)
Query: 34 NIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHL 93
N+ S NG++ L+ AA + ++L++ H A L T DG T + +A+ +G ++ V +
Sbjct: 126 NVQSVNGFTPLYMAAQENHEEVVKYLLK--HGANQALSTEDGFTPLAVALQQGHDRVVAV 183
Query: 94 LLQH-------------------------FLEEGLNLRSSSARRWAPIHIACRSNHSRCL 128
LL++ L+ N +S + P+HIA H
Sbjct: 184 LLENDSKGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFTPLHIAAHYGHENVG 243
Query: 129 ALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCG 168
LLL+ GA+V + + LHVA ++G +LL G
Sbjct: 244 QLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRG 283
Score = 55.1 bits (131), Expect = 1e-07
Identities = 45/173 (26%), Positives = 72/173 (41%), Gaps = 31/173 (17%)
Query: 34 NIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHL 93
N + + +S LH AA G+ + I L H+A L T G T +HLA G+ + V L
Sbjct: 518 NATTRDNYSPLHIAAKEGQEEVAG--ILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRL 575
Query: 94 LLQH-----------------------------FLEEGLNLRSSSARRWAPIHIACRSNH 124
LL+ LE G + ++++ + P+HIA + N
Sbjct: 576 LLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQ 635
Query: 125 SRCLALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCGGATLADEQN 177
+ LLQ AD + G T LH++ + G + +L++ G A N
Sbjct: 636 MEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGAKANN 688
Score = 55.1 bits (131), Expect = 1e-07
Identities = 42/147 (28%), Positives = 65/147 (43%), Gaps = 8/147 (5%)
Query: 34 NIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHL 93
N S G++ LH +A G I LI+ G D A K +G T +HL + +
Sbjct: 650 NAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGA--KANNGLTAMHLCAQEDHVPVAQI 707
Query: 94 LLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAM 153
L + G + S + + P+H+AC + L++ GADV + T LH A
Sbjct: 708 LYNN----GAEINSKTNAGYTPLHVACHFGQLNMVKFLVENGADVGEKTRASYTPLHQAA 763
Query: 154 EYGAIQCLPILLQCGGATLADEQNQMG 180
+ G C+ LL+ G + +EQ G
Sbjct: 764 QQGHNNCVRYLLENGAS--PNEQTATG 788
Score = 54.3 bits (129), Expect = 2e-07
Identities = 44/130 (33%), Positives = 60/130 (45%), Gaps = 6/130 (4%)
Query: 39 NGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHLLLQHF 98
NG + LH AA R L+ H A T D T +H+A G + LLL
Sbjct: 325 NGLAPLHMAAQGDHVDAARTLLY--HRAPVDDVTVDYLTPLHVAAHCGHVRVAKLLL--- 379
Query: 99 LEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAMEYGAI 158
+ + S + + P+HIAC+ N + + LLL+ A + E G T LHVA GAI
Sbjct: 380 -DRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAI 438
Query: 159 QCLPILLQCG 168
+ LLQ G
Sbjct: 439 NIVIYLLQQG 448
>Hs18252778 [R] KOG0504 FOG: Ankyrin repeat
Length = 587
Score = 68.6 bits (166), Expect = 1e-11
Identities = 58/214 (27%), Positives = 103/214 (48%), Gaps = 14/214 (6%)
Query: 5 PRIRLREAIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGH 64
P L +AI G ++ ++K +L E + GW LH AA+YG+ + C ++Q +
Sbjct: 57 PADPLIKAIKDGDEEALKTMIKEGKNLAE--PNKEGWLPLHEAAYYGQ-VGCLKVLQRAY 113
Query: 65 DATAMLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNH 124
T +T +T ++LA +G + LLQ E ++ +S R P++ AC +
Sbjct: 114 PGTIDQRTLQEETAVYLATCRGHLDCLLSLLQAGAEPDISNKS----RETPLYKACERKN 169
Query: 125 SRCLALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCGGATLADEQNQMGI--- 181
+ + +L+Q AD G T LH ++ ++ + IL+ GGA + + +N GI
Sbjct: 170 AEAVKILVQHNADTNHRCNRGWTALHESVSRNDLEVMQILVS-GGAKV-ESKNAYGITPL 227
Query: 182 -VARQVGNCDETIKKFDQFAAEIRKGVSSGSSTV 214
VA Q G E ++ ++ A+I S +S +
Sbjct: 228 FVAAQSGQL-EALRFLAKYGADINTQASDNASAL 260
>Hs20538133 [R] KOG0504 FOG: Ankyrin repeat
Length = 899
Score = 68.2 bits (165), Expect = 2e-11
Identities = 43/135 (31%), Positives = 65/135 (47%), Gaps = 6/135 (4%)
Query: 34 NIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHL 93
N+ S +G + LH A +GR+ + +IQ G A + +G+T +H+A G E L
Sbjct: 146 NMKSKDGKTPLHMTALHGRFSRSQTIIQSG--AVIDCEDKNGNTPLHIAARYGHE----L 199
Query: 94 LLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAM 153
L+ + G + P+H+A S S C LL G D+ D+ G T LH A
Sbjct: 200 LINTLITSGADTAKRGIHGMFPLHLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAAA 259
Query: 154 EYGAIQCLPILLQCG 168
G ++CL +LL G
Sbjct: 260 AGGNLECLNLLLNTG 274
Score = 60.5 bits (145), Expect = 3e-09
Identities = 43/167 (25%), Positives = 79/167 (46%), Gaps = 9/167 (5%)
Query: 12 AIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLK 71
A G + VV+ ++ ++ ++ LH AA G + ++L+ LG D
Sbjct: 26 AAYMGHIEVVKLLVSHGAEV--TCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEP-N 82
Query: 72 TYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSR-CLAL 130
Y G+T +H+A G + V+ L+ + G + + + + P+H A S H CL L
Sbjct: 83 AY-GNTPLHVACYNGQDVVVNELI----DCGAIVNQKNEKGFTPLHFAAASTHGALCLEL 137
Query: 131 LLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCGGATLADEQN 177
L+ GADV ++ ++G T LH+ +G ++Q G +++N
Sbjct: 138 LVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKN 184
Score = 55.8 bits (133), Expect = 8e-08
Identities = 44/148 (29%), Positives = 71/148 (47%), Gaps = 17/148 (11%)
Query: 30 DLLENIDSTNGWSSLHYAAFYGRYLICRHLIQ--------LGHDATAMLKTYDGDTCI-- 79
D I G++++HY+A YG + +C LI + T ML D I
Sbjct: 341 DANPGIRDKQGYNAVHYSAAYG-HRLCLQLIASETPLDVLMETSGTDMLSDSDNRATISP 399
Query: 80 -HLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADV 138
HLA G Q + +L+Q L+ L++R+SS R P+ +A H C+ +L+ GA +
Sbjct: 400 LHLAAYHGHHQALEVLVQSLLD--LDVRNSSGR--TPLDLAAFKGHVECVDVLINQGASI 455
Query: 139 TLEDE-EGNTGLHVAMEYGAIQCLPILL 165
++D T +H A G +CL +L+
Sbjct: 456 LVKDYILKRTPIHAAATNGHSECLRLLI 483
Score = 53.9 bits (128), Expect = 3e-07
Identities = 44/163 (26%), Positives = 68/163 (40%), Gaps = 7/163 (4%)
Query: 9 LREAIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATA 68
L A G + VV+ +L D+ N + G + LH A + G+ ++ LI G A
Sbjct: 56 LHAAASSGMISVVKYLLDLGVDM--NEPNAYGNTPLHVACYNGQDVVVNELIDCG--AIV 111
Query: 69 MLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCL 128
K G T +H A L L+ + G ++ S P+H+
Sbjct: 112 NQKNEKGFTPLHFAAASTHGA---LCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRS 168
Query: 129 ALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCGGAT 171
++Q GA + ED+ GNT LH+A YG + L+ G T
Sbjct: 169 QTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADT 211
Score = 53.5 bits (127), Expect = 4e-07
Identities = 37/128 (28%), Positives = 66/128 (50%), Gaps = 9/128 (7%)
Query: 43 SLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEG 102
++H+AA+ G + + L+ G + T K T +H A + G V ++ L+ G
Sbjct: 22 AIHWAAYMGHIEVVKLLVSHGAEVTC--KDKKSYTPLHAAASSGMISVV----KYLLDLG 75
Query: 103 LNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLH--VAMEYGAIQC 160
+++ +A P+H+AC + + L+ CGA V ++E+G T LH A +GA+ C
Sbjct: 76 VDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGAL-C 134
Query: 161 LPILLQCG 168
L +L+ G
Sbjct: 135 LELLVGNG 142
Score = 52.0 bits (123), Expect = 1e-06
Identities = 43/131 (32%), Positives = 60/131 (44%), Gaps = 11/131 (8%)
Query: 39 NGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYD--GDTCIHLAITKGDEQTVHLLLQ 96
+G LH AA G CR L+ G D + T D G TC+H A G+ + ++LLL
Sbjct: 217 HGMFPLHLAALSGFSDCCRKLLSSGFD----IDTPDDFGRTCLHAAAAGGNLECLNLLLN 272
Query: 97 HFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAMEYG 156
G + +P+H A + + +CL L+ GA V DE G T LH A
Sbjct: 273 ----TGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAATSD 328
Query: 157 AI-QCLPILLQ 166
+CL LL+
Sbjct: 329 TDGKCLEYLLR 339
Score = 52.0 bits (123), Expect = 1e-06
Identities = 41/166 (24%), Positives = 72/166 (42%), Gaps = 11/166 (6%)
Query: 16 GKLGVVRRILKRWPDLLEN--IDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTY 73
G +GV+ +L+ + N +G+++LH+A + G L++ + +
Sbjct: 576 GHIGVLGALLQSAASMDANPATADNHGYTALHWACYNGHETCVELLLE-----QEVFQKT 630
Query: 74 DGDTC--IHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALL 131
+G+ +H A+ +E +L+ +N S R P+H A ++H CL LL
Sbjct: 631 EGNAFSPLHCAVINDNEGAAEMLIDTLGASIVNATDSKGR--TPLHAAAFTDHVECLQLL 688
Query: 132 LQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCGGATLADEQN 177
L A V D G T L +A E G + +L+ A L + N
Sbjct: 689 LSHNAQVNSVDSTGKTPLMMAAENGQTNTVEMLVSSASAELTLQDN 734
Score = 51.2 bits (121), Expect = 2e-06
Identities = 41/135 (30%), Positives = 56/135 (41%), Gaps = 6/135 (4%)
Query: 36 DSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHLLL 95
+ NG + LH AA YG L+ LI G D + G +HLA G LL
Sbjct: 181 EDKNGNTPLHIAARYGHELLINTLITSGADTAK--RGIHGMFPLHLAALSGFSDCCRKLL 238
Query: 96 QHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAMEY 155
G ++ + +H A + CL LLL GAD +D+ G + LH A
Sbjct: 239 S----SGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAAN 294
Query: 156 GAIQCLPILLQCGGA 170
QCL L+ G +
Sbjct: 295 CNYQCLFALVGSGAS 309
Score = 50.4 bits (119), Expect = 4e-06
Identities = 40/141 (28%), Positives = 71/141 (49%), Gaps = 6/141 (4%)
Query: 34 NIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYD-GDTCIHLAITKGDEQTVH 92
++ +++G + L AAF G LI G A+ ++K Y T IH A T G + +
Sbjct: 423 DVRNSSGRTPLDLAAFKGHVECVDVLINQG--ASILVKDYILKRTPIHAAATNGHSECLR 480
Query: 93 LLLQHFL-EEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHV 151
LL+ + + ++++ + + P+ ++ + H+ C+ LL GA+V +D+ G T LH
Sbjct: 481 LLIGNAEPQNAVDIQDGNGQ--TPLMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHR 538
Query: 152 AMEYGAIQCLPILLQCGGATL 172
G +C+ LLQ G L
Sbjct: 539 GAVTGHEECVDALLQHGAKCL 559
>Hs10947054 [M] KOG4177 Ankyrin
Length = 1872
Score = 68.2 bits (165), Expect = 2e-11
Identities = 48/151 (31%), Positives = 79/151 (51%), Gaps = 8/151 (5%)
Query: 16 GKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDG 75
G L V LK D+ N + NG ++LH AA G + + L LG ++ T G
Sbjct: 42 GNLDKVVEYLKGGIDI--NTCNQNGLNALHLAAKEGHVGLVQEL--LGRGSSVDSATKKG 97
Query: 76 DTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCG 135
+T +H+A G + V +L++ EG N+ + S + P+++A + NH + LL+ G
Sbjct: 98 NTALHIASLAGQAEVVKVLVK----EGANINAQSQNGFTPLYMAAQENHIDVVKYLLENG 153
Query: 136 ADVTLEDEEGNTGLHVAMEYGAIQCLPILLQ 166
A+ + E+G T L VA++ G Q + ILL+
Sbjct: 154 ANQSTATEDGFTPLAVALQQGHNQAVAILLE 184
Score = 66.6 bits (161), Expect = 5e-11
Identities = 50/175 (28%), Positives = 85/175 (48%), Gaps = 10/175 (5%)
Query: 12 AIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLK 71
A G L +V +L+ ++ + G ++LH AA G+ + R L++ G A +
Sbjct: 438 AAFMGHLNIVLLLLQNGAS--PDVTNIRGETALHMAARAGQVEVVRCLLRNG--ALVDAR 493
Query: 72 TYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALL 131
+ T +H+A G + V LLLQH +++ + P+HI+ R ++L
Sbjct: 494 AREEQTPLHIASRLGKTEIVQLLLQHMAHPD----AATTNGYTPLHISAREGQVDVASVL 549
Query: 132 LQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCGGATLADEQNQMGIVARQV 186
L+ GA +L ++G T LHVA +YG++ +LLQ A AD + G+ V
Sbjct: 550 LEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAA--ADSAGKNGLTPLHV 602
Score = 65.9 bits (159), Expect = 8e-11
Identities = 51/152 (33%), Positives = 78/152 (50%), Gaps = 10/152 (6%)
Query: 20 VVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLIC-RHLIQLGHDATAMLKTYDGDTC 78
VV +L+R LL + NG S LH AA G ++ C +HL+Q H A T D T
Sbjct: 314 VVELLLERGAPLLAR--TKNGLSPLHMAA-QGDHVECVKHLLQ--HKAPVDDVTLDYLTA 368
Query: 79 IHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADV 138
+H+A G + LLL ++ N + + + P+HIAC+ N + + LL++ GA +
Sbjct: 369 LHVAAHCGHYRVTKLLL----DKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASI 424
Query: 139 TLEDEEGNTGLHVAMEYGAIQCLPILLQCGGA 170
E G T +HVA G + + +LLQ G +
Sbjct: 425 QAITESGLTPIHVAAFMGHLNIVLLLLQNGAS 456
Score = 62.8 bits (151), Expect = 7e-10
Identities = 40/136 (29%), Positives = 69/136 (50%), Gaps = 6/136 (4%)
Query: 31 LLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQT 90
++ N + +G++ LH AA YG + L+ G A +G T +H+A +G+
Sbjct: 224 MMVNRTTESGFTPLHIAAHYGNVNVATLLLNRG--AAVDFTARNGITPLHVASKRGNTNM 281
Query: 91 VHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLH 150
V LLL + G + + + P+H A RS H + + LLL+ GA + + G + LH
Sbjct: 282 VKLLL----DRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPLLARTKNGLSPLH 337
Query: 151 VAMEYGAIQCLPILLQ 166
+A + ++C+ LLQ
Sbjct: 338 MAAQGDHVECVKHLLQ 353
Score = 60.1 bits (144), Expect = 4e-09
Identities = 42/135 (31%), Positives = 72/135 (53%), Gaps = 6/135 (4%)
Query: 34 NIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHL 93
++ + G++ LH AA YG + + L+Q A + K +G T +H+A D Q V L
Sbjct: 557 SLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGK--NGLTPLHVA-AHYDNQKVAL 613
Query: 94 LLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAM 153
LL LE+G + +++ + P+HIA + N + + LL GA+ + ++G T LH+A
Sbjct: 614 LL---LEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLAS 670
Query: 154 EYGAIQCLPILLQCG 168
+ G + +LL G
Sbjct: 671 QEGHTDMVTLLLDKG 685
Score = 59.3 bits (142), Expect = 8e-09
Identities = 51/184 (27%), Positives = 80/184 (42%), Gaps = 14/184 (7%)
Query: 9 LREAIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATA 68
L A G L V + +L+R + NG + LH AA Y + L++ G A
Sbjct: 567 LHVAAKYGSLDVAKLLLQR--RAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHA 624
Query: 69 MLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCL 128
K +G T +H+A K Q LL + E + + P+H+A + H+ +
Sbjct: 625 TAK--NGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVT----PLHLASQEGHTDMV 678
Query: 129 ALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCGGATLADEQNQMG----IVAR 184
LLL GA++ + + G T LH+A + + IL + G D ++G IVA
Sbjct: 679 TLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGAD--QDAHTKLGYTPLIVAC 736
Query: 185 QVGN 188
GN
Sbjct: 737 HYGN 740
Score = 59.3 bits (142), Expect = 8e-09
Identities = 41/146 (28%), Positives = 73/146 (49%), Gaps = 9/146 (6%)
Query: 42 SSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEE 101
++LH AA G Y + + L+ + A + +G T +H+A K + + LL+++
Sbjct: 367 TALHVAAHCGHYRVTKLLLDKRANPNA--RALNGFTPLHIACKKNRIKVMELLVKY---- 420
Query: 102 GLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCL 161
G ++++ + PIH+A H + LLLQ GA + + G T LH+A G ++ +
Sbjct: 421 GASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVV 480
Query: 162 PILLQCGG---ATLADEQNQMGIVAR 184
LL+ G A +EQ + I +R
Sbjct: 481 RCLLRNGALVDARAREEQTPLHIASR 506
Score = 58.9 bits (141), Expect = 1e-08
Identities = 51/170 (30%), Positives = 84/170 (49%), Gaps = 20/170 (11%)
Query: 9 LREAIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATA 68
L A + G+ VV+ ++K ++ N S NG++ L+ AA + ++L++ G A
Sbjct: 101 LHIASLAGQAEVVKVLVKEGANI--NAQSQNGFTPLYMAAQENHIDVVKYLLENG--ANQ 156
Query: 69 MLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCL 128
T DG T + +A+ +G Q V +LL++ + + L + +HIA R + ++
Sbjct: 157 STATEDGFTPLAVALQQGHNQAVAILLENDTKGKVRLPA--------LHIAARKDDTKSA 208
Query: 129 ALLLQ--CGADVTLE------DEEGNTGLHVAMEYGAIQCLPILLQCGGA 170
ALLLQ ADV + E G T LH+A YG + +LL G A
Sbjct: 209 ALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAA 258
Score = 52.8 bits (125), Expect = 7e-07
Identities = 41/154 (26%), Positives = 70/154 (44%), Gaps = 9/154 (5%)
Query: 34 NIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHL 93
NI + G + LH A+ G + L+ G A + T G T +HLA + +
Sbjct: 656 NIVTKQGVTPLHLASQEGHTDMVTLLLDKG--ANIHMSTKSGLTSLHLAAQEDKVNVADI 713
Query: 94 LLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAM 153
L +H ++ + + + P+ +AC + + + LL+ GA+V + + G T LH A
Sbjct: 714 LTKHGADQDAHTKLG----YTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAA 769
Query: 154 EYGAIQCLPILLQCG---GATLADEQNQMGIVAR 184
+ G + +LLQ G AT A+ + I R
Sbjct: 770 QQGHTHIINVLLQHGAKPNATTANGNTALAIAKR 803
Score = 51.6 bits (122), Expect = 2e-06
Identities = 42/156 (26%), Positives = 74/156 (46%), Gaps = 8/156 (5%)
Query: 9 LREAIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATA 68
L A +G +V +L + ++ ++ + +G +SLH AA + + L + G D A
Sbjct: 666 LHLASQEGHTDMVTLLLDKGANI--HMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDA 723
Query: 69 MLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCL 128
K G T + +A G+ + V+ LL+ +G N+ + + + P+H A + H+ +
Sbjct: 724 HTKL--GYTPLIVACHYGNVKMVNFLLK----QGANVNAKTKNGYTPLHQAAQQGHTHII 777
Query: 129 ALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPIL 164
+LLQ GA GNT L +A G I + L
Sbjct: 778 NVLLQHGAKPNATTANGNTALAIAKRLGYISVVDTL 813
>Hs10947052 [M] KOG4177 Ankyrin
Length = 3957
Score = 68.2 bits (165), Expect = 2e-11
Identities = 48/151 (31%), Positives = 79/151 (51%), Gaps = 8/151 (5%)
Query: 16 GKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDG 75
G L V LK D+ N + NG ++LH AA G + + L LG ++ T G
Sbjct: 42 GNLDKVVEYLKGGIDI--NTCNQNGLNALHLAAKEGHVGLVQEL--LGRGSSVDSATKKG 97
Query: 76 DTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCG 135
+T +H+A G + V +L++ EG N+ + S + P+++A + NH + LL+ G
Sbjct: 98 NTALHIASLAGQAEVVKVLVK----EGANINAQSQNGFTPLYMAAQENHIDVVKYLLENG 153
Query: 136 ADVTLEDEEGNTGLHVAMEYGAIQCLPILLQ 166
A+ + E+G T L VA++ G Q + ILL+
Sbjct: 154 ANQSTATEDGFTPLAVALQQGHNQAVAILLE 184
Score = 66.6 bits (161), Expect = 5e-11
Identities = 50/175 (28%), Positives = 85/175 (48%), Gaps = 10/175 (5%)
Query: 12 AIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLK 71
A G L +V +L+ ++ + G ++LH AA G+ + R L++ G A +
Sbjct: 438 AAFMGHLNIVLLLLQNGAS--PDVTNIRGETALHMAARAGQVEVVRCLLRNG--ALVDAR 493
Query: 72 TYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALL 131
+ T +H+A G + V LLLQH +++ + P+HI+ R ++L
Sbjct: 494 AREEQTPLHIASRLGKTEIVQLLLQHMAHPD----AATTNGYTPLHISAREGQVDVASVL 549
Query: 132 LQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCGGATLADEQNQMGIVARQV 186
L+ GA +L ++G T LHVA +YG++ +LLQ A AD + G+ V
Sbjct: 550 LEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAA--ADSAGKNGLTPLHV 602
Score = 65.9 bits (159), Expect = 8e-11
Identities = 51/152 (33%), Positives = 78/152 (50%), Gaps = 10/152 (6%)
Query: 20 VVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLIC-RHLIQLGHDATAMLKTYDGDTC 78
VV +L+R LL + NG S LH AA G ++ C +HL+Q H A T D T
Sbjct: 314 VVELLLERGAPLLAR--TKNGLSPLHMAA-QGDHVECVKHLLQ--HKAPVDDVTLDYLTA 368
Query: 79 IHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADV 138
+H+A G + LLL ++ N + + + P+HIAC+ N + + LL++ GA +
Sbjct: 369 LHVAAHCGHYRVTKLLL----DKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASI 424
Query: 139 TLEDEEGNTGLHVAMEYGAIQCLPILLQCGGA 170
E G T +HVA G + + +LLQ G +
Sbjct: 425 QAITESGLTPIHVAAFMGHLNIVLLLLQNGAS 456
Score = 62.8 bits (151), Expect = 7e-10
Identities = 40/136 (29%), Positives = 69/136 (50%), Gaps = 6/136 (4%)
Query: 31 LLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQT 90
++ N + +G++ LH AA YG + L+ G A +G T +H+A +G+
Sbjct: 224 MMVNRTTESGFTPLHIAAHYGNVNVATLLLNRG--AAVDFTARNGITPLHVASKRGNTNM 281
Query: 91 VHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLH 150
V LLL + G + + + P+H A RS H + + LLL+ GA + + G + LH
Sbjct: 282 VKLLL----DRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPLLARTKNGLSPLH 337
Query: 151 VAMEYGAIQCLPILLQ 166
+A + ++C+ LLQ
Sbjct: 338 MAAQGDHVECVKHLLQ 353
Score = 60.1 bits (144), Expect = 4e-09
Identities = 42/135 (31%), Positives = 72/135 (53%), Gaps = 6/135 (4%)
Query: 34 NIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHL 93
++ + G++ LH AA YG + + L+Q A + K +G T +H+A D Q V L
Sbjct: 557 SLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGK--NGLTPLHVA-AHYDNQKVAL 613
Query: 94 LLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAM 153
LL LE+G + +++ + P+HIA + N + + LL GA+ + ++G T LH+A
Sbjct: 614 LL---LEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLAS 670
Query: 154 EYGAIQCLPILLQCG 168
+ G + +LL G
Sbjct: 671 QEGHTDMVTLLLDKG 685
Score = 59.3 bits (142), Expect = 8e-09
Identities = 51/184 (27%), Positives = 80/184 (42%), Gaps = 14/184 (7%)
Query: 9 LREAIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATA 68
L A G L V + +L+R + NG + LH AA Y + L++ G A
Sbjct: 567 LHVAAKYGSLDVAKLLLQR--RAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHA 624
Query: 69 MLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCL 128
K +G T +H+A K Q LL + E + + P+H+A + H+ +
Sbjct: 625 TAK--NGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVT----PLHLASQEGHTDMV 678
Query: 129 ALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCGGATLADEQNQMG----IVAR 184
LLL GA++ + + G T LH+A + + IL + G D ++G IVA
Sbjct: 679 TLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGAD--QDAHTKLGYTPLIVAC 736
Query: 185 QVGN 188
GN
Sbjct: 737 HYGN 740
Score = 59.3 bits (142), Expect = 8e-09
Identities = 41/146 (28%), Positives = 73/146 (49%), Gaps = 9/146 (6%)
Query: 42 SSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEE 101
++LH AA G Y + + L+ + A + +G T +H+A K + + LL+++
Sbjct: 367 TALHVAAHCGHYRVTKLLLDKRANPNA--RALNGFTPLHIACKKNRIKVMELLVKY---- 420
Query: 102 GLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCL 161
G ++++ + PIH+A H + LLLQ GA + + G T LH+A G ++ +
Sbjct: 421 GASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVV 480
Query: 162 PILLQCGG---ATLADEQNQMGIVAR 184
LL+ G A +EQ + I +R
Sbjct: 481 RCLLRNGALVDARAREEQTPLHIASR 506
Score = 58.9 bits (141), Expect = 1e-08
Identities = 51/170 (30%), Positives = 84/170 (49%), Gaps = 20/170 (11%)
Query: 9 LREAIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATA 68
L A + G+ VV+ ++K ++ N S NG++ L+ AA + ++L++ G A
Sbjct: 101 LHIASLAGQAEVVKVLVKEGANI--NAQSQNGFTPLYMAAQENHIDVVKYLLENG--ANQ 156
Query: 69 MLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCL 128
T DG T + +A+ +G Q V +LL++ + + L + +HIA R + ++
Sbjct: 157 STATEDGFTPLAVALQQGHNQAVAILLENDTKGKVRLPA--------LHIAARKDDTKSA 208
Query: 129 ALLLQ--CGADVTLE------DEEGNTGLHVAMEYGAIQCLPILLQCGGA 170
ALLLQ ADV + E G T LH+A YG + +LL G A
Sbjct: 209 ALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAA 258
Score = 52.8 bits (125), Expect = 7e-07
Identities = 41/154 (26%), Positives = 70/154 (44%), Gaps = 9/154 (5%)
Query: 34 NIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHL 93
NI + G + LH A+ G + L+ G A + T G T +HLA + +
Sbjct: 656 NIVTKQGVTPLHLASQEGHTDMVTLLLDKG--ANIHMSTKSGLTSLHLAAQEDKVNVADI 713
Query: 94 LLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAM 153
L +H ++ + + + P+ +AC + + + LL+ GA+V + + G T LH A
Sbjct: 714 LTKHGADQDAHTKLG----YTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAA 769
Query: 154 EYGAIQCLPILLQCG---GATLADEQNQMGIVAR 184
+ G + +LLQ G AT A+ + I R
Sbjct: 770 QQGHTHIINVLLQHGAKPNATTANGNTALAIAKR 803
Score = 51.6 bits (122), Expect = 2e-06
Identities = 42/156 (26%), Positives = 74/156 (46%), Gaps = 8/156 (5%)
Query: 9 LREAIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATA 68
L A +G +V +L + ++ ++ + +G +SLH AA + + L + G D A
Sbjct: 666 LHLASQEGHTDMVTLLLDKGANI--HMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDA 723
Query: 69 MLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCL 128
K G T + +A G+ + V+ LL+ +G N+ + + + P+H A + H+ +
Sbjct: 724 HTKL--GYTPLIVACHYGNVKMVNFLLK----QGANVNAKTKNGYTPLHQAAQQGHTHII 777
Query: 129 ALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPIL 164
+LLQ GA GNT L +A G I + L
Sbjct: 778 NVLLQHGAKPNATTANGNTALAIAKRLGYISVVDTL 813
>Hs10947042 [M] KOG4177 Ankyrin
Length = 1719
Score = 67.8 bits (164), Expect = 2e-11
Identities = 48/132 (36%), Positives = 68/132 (51%), Gaps = 6/132 (4%)
Query: 39 NGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHLLLQHF 98
NG S +H AA G +L C L+ L +DA T D T +H+A G + +LL
Sbjct: 304 NGLSPIHMAA-QGDHLDCVRLL-LQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLL--- 358
Query: 99 LEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAMEYGAI 158
++G S + + P+HIAC+ NH R + LLL+ GA + E G T LHVA G +
Sbjct: 359 -DKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHL 417
Query: 159 QCLPILLQCGGA 170
+ LLQ G +
Sbjct: 418 PIVKNLLQRGAS 429
Score = 62.8 bits (151), Expect = 7e-10
Identities = 47/158 (29%), Positives = 72/158 (44%), Gaps = 8/158 (5%)
Query: 9 LREAIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATA 68
L A G L +V+ +L+R N+ + + LH AA G + ++L+Q + A
Sbjct: 408 LHVASFMGHLPIVKNLLQRGAS--PNVSNVKVETPLHMAARAGHTEVAKYLLQ--NKAKV 463
Query: 69 MLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCL 128
K D T +H A G V LLL E N ++ P+HIA R H +
Sbjct: 464 NAKAKDDQTPLHCAARIGHTNMVKLLL----ENNANPNLATTAGHTPLHIAAREGHVETV 519
Query: 129 ALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQ 166
LL+ A ++G T LHVA +YG ++ +LL+
Sbjct: 520 LALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLE 557
Score = 61.6 bits (148), Expect = 2e-09
Identities = 55/208 (26%), Positives = 93/208 (44%), Gaps = 15/208 (7%)
Query: 9 LREAIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATA 68
L A GK+ V +L+R D N NG + LH A + I + L+ G +
Sbjct: 540 LHVAAKYGKVRVAELLLER--DAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHS 597
Query: 69 MLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCL 128
++G T +H+A + + LLQ+ G + + S + P+H+A + H+ +
Sbjct: 598 --PAWNGYTPLHIAAKQNQVEVARSLLQY----GGSANAESVQGVTPLHLAAQEGHAEMV 651
Query: 129 ALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCGGATLADEQNQMGI----VAR 184
ALLL A+ L ++ G T LH+ + G + +L++ G + D +MG VA
Sbjct: 652 ALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHG--VMVDATTRMGYTPLHVAS 709
Query: 185 QVGNCDETIKKFDQFAAEIRKGVSSGSS 212
GN + +K Q A++ G S
Sbjct: 710 HYGNI-KLVKFLLQHQADVNAKTKLGYS 736
Score = 61.2 bits (147), Expect = 2e-09
Identities = 40/138 (28%), Positives = 69/138 (49%), Gaps = 10/138 (7%)
Query: 29 PDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDE 88
PD+L S G++ LH AA Y + + L+ G A+ +G T +H+A +G+
Sbjct: 199 PDVL----SKTGFTPLHIAAHYENLNVAQLLLNRG--ASVNFTPQNGITPLHIASRRGNV 252
Query: 89 QTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTG 148
V LLL + G + + + P+H A R+ H R +LL GA + + + G +
Sbjct: 253 IMVRLLL----DRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSP 308
Query: 149 LHVAMEYGAIQCLPILLQ 166
+H+A + + C+ +LLQ
Sbjct: 309 IHMAAQGDHLDCVRLLLQ 326
Score = 58.5 bits (140), Expect = 1e-08
Identities = 46/151 (30%), Positives = 71/151 (46%), Gaps = 8/151 (5%)
Query: 18 LGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDT 77
L V + +L R + N NG + LH A+ G ++ R L+ G A KT D T
Sbjct: 219 LNVAQLLLNRGASV--NFTPQNGITPLHIASRRGNVIMVRLLLDRG--AQIETKTKDELT 274
Query: 78 CIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGAD 137
+H A G + +LL H G +++ + +PIH+A + +H C+ LLLQ A+
Sbjct: 275 PLHCAARNGHVRISEILLDH----GAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAE 330
Query: 138 VTLEDEEGNTGLHVAMEYGAIQCLPILLQCG 168
+ + T LHVA G + +LL G
Sbjct: 331 IDDITLDHLTPLHVAAHCGHHRVAKVLLDKG 361
Score = 57.0 bits (136), Expect = 4e-08
Identities = 37/136 (27%), Positives = 69/136 (50%), Gaps = 8/136 (5%)
Query: 34 NIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAM-LKTYDGDTCIHLAITKGDEQTVH 92
N + NG + LH A+ G + +++L H + T G+T +H+A G ++ V
Sbjct: 39 NTCNQNGLNGLHLASKEGHV---KMVVELLHKEIILETTTKKGNTALHIAALAGQDEVVR 95
Query: 93 LLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVA 152
L+ + G N+ + S + + P+++A + NH + LL+ GA+ + E+G T L VA
Sbjct: 96 ELVNY----GANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVA 151
Query: 153 MEYGAIQCLPILLQCG 168
++ G + L+ G
Sbjct: 152 LQQGHENVVAHLINYG 167
Score = 54.7 bits (130), Expect = 2e-07
Identities = 46/191 (24%), Positives = 83/191 (43%), Gaps = 33/191 (17%)
Query: 9 LREAIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATA 68
L A+ L +V+ +L R + + NG++ LH AA + + R L+Q G A A
Sbjct: 573 LHVAVHHNNLDIVKLLLPRGGS--PHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANA 630
Query: 69 MLKTYDGDTCIHLAITKGDEQTVHLLLQH-----------------------------FL 99
++ G T +HLA +G + V LLL +
Sbjct: 631 --ESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLI 688
Query: 100 EEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAMEYGAIQ 159
+ G+ + +++ + P+H+A + + + LLQ ADV + + G + LH A + G
Sbjct: 689 KHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTD 748
Query: 160 CLPILLQCGGA 170
+ +LL+ G +
Sbjct: 749 IVTLLLKNGAS 759
Score = 52.8 bits (125), Expect = 7e-07
Identities = 46/169 (27%), Positives = 78/169 (45%), Gaps = 12/169 (7%)
Query: 9 LREAIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATA 68
L A + G+ VVR ++ ++ N S G++ L+ AA + + L++ G A
Sbjct: 82 LHIAALAGQDEVVRELVNYGANV--NAQSQKGFTPLYMAAQENHLEVVKFLLENG--ANQ 137
Query: 69 MLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCL 128
+ T DG T + +A+ +G E V L+ N + R +HIA R++ +R
Sbjct: 138 NVATEDGFTPLAVALQQGHENVVAHLI--------NYGTKGKVRLPALHIAARNDDTRTA 189
Query: 129 ALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCGGATLADEQN 177
A+LLQ + + + G T LH+A Y + +LL G + QN
Sbjct: 190 AVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQN 238
>Hs10947040 [M] KOG4177 Ankyrin
Length = 1880
Score = 67.8 bits (164), Expect = 2e-11
Identities = 48/132 (36%), Positives = 68/132 (51%), Gaps = 6/132 (4%)
Query: 39 NGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHLLLQHF 98
NG S +H AA G +L C L+ L +DA T D T +H+A G + +LL
Sbjct: 304 NGLSPIHMAA-QGDHLDCVRLL-LQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLL--- 358
Query: 99 LEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAMEYGAI 158
++G S + + P+HIAC+ NH R + LLL+ GA + E G T LHVA G +
Sbjct: 359 -DKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHL 417
Query: 159 QCLPILLQCGGA 170
+ LLQ G +
Sbjct: 418 PIVKNLLQRGAS 429
Score = 62.8 bits (151), Expect = 7e-10
Identities = 47/158 (29%), Positives = 72/158 (44%), Gaps = 8/158 (5%)
Query: 9 LREAIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATA 68
L A G L +V+ +L+R N+ + + LH AA G + ++L+Q + A
Sbjct: 408 LHVASFMGHLPIVKNLLQRGAS--PNVSNVKVETPLHMAARAGHTEVAKYLLQ--NKAKV 463
Query: 69 MLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCL 128
K D T +H A G V LLL E N ++ P+HIA R H +
Sbjct: 464 NAKAKDDQTPLHCAARIGHTNMVKLLL----ENNANPNLATTAGHTPLHIAAREGHVETV 519
Query: 129 ALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQ 166
LL+ A ++G T LHVA +YG ++ +LL+
Sbjct: 520 LALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLE 557
Score = 61.6 bits (148), Expect = 2e-09
Identities = 55/208 (26%), Positives = 93/208 (44%), Gaps = 15/208 (7%)
Query: 9 LREAIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATA 68
L A GK+ V +L+R D N NG + LH A + I + L+ G +
Sbjct: 540 LHVAAKYGKVRVAELLLER--DAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHS 597
Query: 69 MLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCL 128
++G T +H+A + + LLQ+ G + + S + P+H+A + H+ +
Sbjct: 598 --PAWNGYTPLHIAAKQNQVEVARSLLQY----GGSANAESVQGVTPLHLAAQEGHAEMV 651
Query: 129 ALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCGGATLADEQNQMGI----VAR 184
ALLL A+ L ++ G T LH+ + G + +L++ G + D +MG VA
Sbjct: 652 ALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHG--VMVDATTRMGYTPLHVAS 709
Query: 185 QVGNCDETIKKFDQFAAEIRKGVSSGSS 212
GN + +K Q A++ G S
Sbjct: 710 HYGNI-KLVKFLLQHQADVNAKTKLGYS 736
Score = 61.2 bits (147), Expect = 2e-09
Identities = 40/138 (28%), Positives = 69/138 (49%), Gaps = 10/138 (7%)
Query: 29 PDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDE 88
PD+L S G++ LH AA Y + + L+ G A+ +G T +H+A +G+
Sbjct: 199 PDVL----SKTGFTPLHIAAHYENLNVAQLLLNRG--ASVNFTPQNGITPLHIASRRGNV 252
Query: 89 QTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTG 148
V LLL + G + + + P+H A R+ H R +LL GA + + + G +
Sbjct: 253 IMVRLLL----DRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSP 308
Query: 149 LHVAMEYGAIQCLPILLQ 166
+H+A + + C+ +LLQ
Sbjct: 309 IHMAAQGDHLDCVRLLLQ 326
Score = 58.5 bits (140), Expect = 1e-08
Identities = 46/151 (30%), Positives = 71/151 (46%), Gaps = 8/151 (5%)
Query: 18 LGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDT 77
L V + +L R + N NG + LH A+ G ++ R L+ G A KT D T
Sbjct: 219 LNVAQLLLNRGASV--NFTPQNGITPLHIASRRGNVIMVRLLLDRG--AQIETKTKDELT 274
Query: 78 CIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGAD 137
+H A G + +LL H G +++ + +PIH+A + +H C+ LLLQ A+
Sbjct: 275 PLHCAARNGHVRISEILLDH----GAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAE 330
Query: 138 VTLEDEEGNTGLHVAMEYGAIQCLPILLQCG 168
+ + T LHVA G + +LL G
Sbjct: 331 IDDITLDHLTPLHVAAHCGHHRVAKVLLDKG 361
Score = 57.0 bits (136), Expect = 4e-08
Identities = 37/136 (27%), Positives = 69/136 (50%), Gaps = 8/136 (5%)
Query: 34 NIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAM-LKTYDGDTCIHLAITKGDEQTVH 92
N + NG + LH A+ G + +++L H + T G+T +H+A G ++ V
Sbjct: 39 NTCNQNGLNGLHLASKEGHV---KMVVELLHKEIILETTTKKGNTALHIAALAGQDEVVR 95
Query: 93 LLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVA 152
L+ + G N+ + S + + P+++A + NH + LL+ GA+ + E+G T L VA
Sbjct: 96 ELVNY----GANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVA 151
Query: 153 MEYGAIQCLPILLQCG 168
++ G + L+ G
Sbjct: 152 LQQGHENVVAHLINYG 167
Score = 54.7 bits (130), Expect = 2e-07
Identities = 46/191 (24%), Positives = 83/191 (43%), Gaps = 33/191 (17%)
Query: 9 LREAIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATA 68
L A+ L +V+ +L R + + NG++ LH AA + + R L+Q G A A
Sbjct: 573 LHVAVHHNNLDIVKLLLPRGGS--PHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANA 630
Query: 69 MLKTYDGDTCIHLAITKGDEQTVHLLLQH-----------------------------FL 99
++ G T +HLA +G + V LLL +
Sbjct: 631 --ESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLI 688
Query: 100 EEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAMEYGAIQ 159
+ G+ + +++ + P+H+A + + + LLQ ADV + + G + LH A + G
Sbjct: 689 KHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTD 748
Query: 160 CLPILLQCGGA 170
+ +LL+ G +
Sbjct: 749 IVTLLLKNGAS 759
Score = 52.8 bits (125), Expect = 7e-07
Identities = 46/169 (27%), Positives = 78/169 (45%), Gaps = 12/169 (7%)
Query: 9 LREAIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATA 68
L A + G+ VVR ++ ++ N S G++ L+ AA + + L++ G A
Sbjct: 82 LHIAALAGQDEVVRELVNYGANV--NAQSQKGFTPLYMAAQENHLEVVKFLLENG--ANQ 137
Query: 69 MLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCL 128
+ T DG T + +A+ +G E V L+ N + R +HIA R++ +R
Sbjct: 138 NVATEDGFTPLAVALQQGHENVVAHLI--------NYGTKGKVRLPALHIAARNDDTRTA 189
Query: 129 ALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCGGATLADEQN 177
A+LLQ + + + G T LH+A Y + +LL G + QN
Sbjct: 190 AVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQN 238
>Hs10947038 [M] KOG4177 Ankyrin
Length = 1881
Score = 67.8 bits (164), Expect = 2e-11
Identities = 48/132 (36%), Positives = 68/132 (51%), Gaps = 6/132 (4%)
Query: 39 NGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHLLLQHF 98
NG S +H AA G +L C L+ L +DA T D T +H+A G + +LL
Sbjct: 304 NGLSPIHMAA-QGDHLDCVRLL-LQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLL--- 358
Query: 99 LEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAMEYGAI 158
++G S + + P+HIAC+ NH R + LLL+ GA + E G T LHVA G +
Sbjct: 359 -DKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHL 417
Query: 159 QCLPILLQCGGA 170
+ LLQ G +
Sbjct: 418 PIVKNLLQRGAS 429
Score = 62.8 bits (151), Expect = 7e-10
Identities = 47/158 (29%), Positives = 72/158 (44%), Gaps = 8/158 (5%)
Query: 9 LREAIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATA 68
L A G L +V+ +L+R N+ + + LH AA G + ++L+Q + A
Sbjct: 408 LHVASFMGHLPIVKNLLQRGAS--PNVSNVKVETPLHMAARAGHTEVAKYLLQ--NKAKV 463
Query: 69 MLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCL 128
K D T +H A G V LLL E N ++ P+HIA R H +
Sbjct: 464 NAKAKDDQTPLHCAARIGHTNMVKLLL----ENNANPNLATTAGHTPLHIAAREGHVETV 519
Query: 129 ALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQ 166
LL+ A ++G T LHVA +YG ++ +LL+
Sbjct: 520 LALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLE 557
Score = 61.6 bits (148), Expect = 2e-09
Identities = 55/208 (26%), Positives = 93/208 (44%), Gaps = 15/208 (7%)
Query: 9 LREAIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATA 68
L A GK+ V +L+R D N NG + LH A + I + L+ G +
Sbjct: 540 LHVAAKYGKVRVAELLLER--DAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHS 597
Query: 69 MLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCL 128
++G T +H+A + + LLQ+ G + + S + P+H+A + H+ +
Sbjct: 598 --PAWNGYTPLHIAAKQNQVEVARSLLQY----GGSANAESVQGVTPLHLAAQEGHAEMV 651
Query: 129 ALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCGGATLADEQNQMGI----VAR 184
ALLL A+ L ++ G T LH+ + G + +L++ G + D +MG VA
Sbjct: 652 ALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHG--VMVDATTRMGYTPLHVAS 709
Query: 185 QVGNCDETIKKFDQFAAEIRKGVSSGSS 212
GN + +K Q A++ G S
Sbjct: 710 HYGNI-KLVKFLLQHQADVNAKTKLGYS 736
Score = 61.2 bits (147), Expect = 2e-09
Identities = 40/138 (28%), Positives = 69/138 (49%), Gaps = 10/138 (7%)
Query: 29 PDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDE 88
PD+L S G++ LH AA Y + + L+ G A+ +G T +H+A +G+
Sbjct: 199 PDVL----SKTGFTPLHIAAHYENLNVAQLLLNRG--ASVNFTPQNGITPLHIASRRGNV 252
Query: 89 QTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTG 148
V LLL + G + + + P+H A R+ H R +LL GA + + + G +
Sbjct: 253 IMVRLLL----DRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSP 308
Query: 149 LHVAMEYGAIQCLPILLQ 166
+H+A + + C+ +LLQ
Sbjct: 309 IHMAAQGDHLDCVRLLLQ 326
Score = 58.5 bits (140), Expect = 1e-08
Identities = 46/151 (30%), Positives = 71/151 (46%), Gaps = 8/151 (5%)
Query: 18 LGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDT 77
L V + +L R + N NG + LH A+ G ++ R L+ G A KT D T
Sbjct: 219 LNVAQLLLNRGASV--NFTPQNGITPLHIASRRGNVIMVRLLLDRG--AQIETKTKDELT 274
Query: 78 CIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGAD 137
+H A G + +LL H G +++ + +PIH+A + +H C+ LLLQ A+
Sbjct: 275 PLHCAARNGHVRISEILLDH----GAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAE 330
Query: 138 VTLEDEEGNTGLHVAMEYGAIQCLPILLQCG 168
+ + T LHVA G + +LL G
Sbjct: 331 IDDITLDHLTPLHVAAHCGHHRVAKVLLDKG 361
Score = 57.0 bits (136), Expect = 4e-08
Identities = 37/136 (27%), Positives = 69/136 (50%), Gaps = 8/136 (5%)
Query: 34 NIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAM-LKTYDGDTCIHLAITKGDEQTVH 92
N + NG + LH A+ G + +++L H + T G+T +H+A G ++ V
Sbjct: 39 NTCNQNGLNGLHLASKEGHV---KMVVELLHKEIILETTTKKGNTALHIAALAGQDEVVR 95
Query: 93 LLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVA 152
L+ + G N+ + S + + P+++A + NH + LL+ GA+ + E+G T L VA
Sbjct: 96 ELVNY----GANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVA 151
Query: 153 MEYGAIQCLPILLQCG 168
++ G + L+ G
Sbjct: 152 LQQGHENVVAHLINYG 167
Score = 54.7 bits (130), Expect = 2e-07
Identities = 46/191 (24%), Positives = 83/191 (43%), Gaps = 33/191 (17%)
Query: 9 LREAIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATA 68
L A+ L +V+ +L R + + NG++ LH AA + + R L+Q G A A
Sbjct: 573 LHVAVHHNNLDIVKLLLPRGGS--PHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANA 630
Query: 69 MLKTYDGDTCIHLAITKGDEQTVHLLLQH-----------------------------FL 99
++ G T +HLA +G + V LLL +
Sbjct: 631 --ESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLI 688
Query: 100 EEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAMEYGAIQ 159
+ G+ + +++ + P+H+A + + + LLQ ADV + + G + LH A + G
Sbjct: 689 KHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTD 748
Query: 160 CLPILLQCGGA 170
+ +LL+ G +
Sbjct: 749 IVTLLLKNGAS 759
Score = 52.8 bits (125), Expect = 7e-07
Identities = 46/169 (27%), Positives = 78/169 (45%), Gaps = 12/169 (7%)
Query: 9 LREAIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATA 68
L A + G+ VVR ++ ++ N S G++ L+ AA + + L++ G A
Sbjct: 82 LHIAALAGQDEVVRELVNYGANV--NAQSQKGFTPLYMAAQENHLEVVKFLLENG--ANQ 137
Query: 69 MLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCL 128
+ T DG T + +A+ +G E V L+ N + R +HIA R++ +R
Sbjct: 138 NVATEDGFTPLAVALQQGHENVVAHLI--------NYGTKGKVRLPALHIAARNDDTRTA 189
Query: 129 ALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCGGATLADEQN 177
A+LLQ + + + G T LH+A Y + +LL G + QN
Sbjct: 190 AVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQN 238
>Hs10947036 [M] KOG4177 Ankyrin
Length = 1856
Score = 67.8 bits (164), Expect = 2e-11
Identities = 48/132 (36%), Positives = 68/132 (51%), Gaps = 6/132 (4%)
Query: 39 NGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHLLLQHF 98
NG S +H AA G +L C L+ L +DA T D T +H+A G + +LL
Sbjct: 304 NGLSPIHMAA-QGDHLDCVRLL-LQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLL--- 358
Query: 99 LEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAMEYGAI 158
++G S + + P+HIAC+ NH R + LLL+ GA + E G T LHVA G +
Sbjct: 359 -DKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHL 417
Query: 159 QCLPILLQCGGA 170
+ LLQ G +
Sbjct: 418 PIVKNLLQRGAS 429
Score = 62.8 bits (151), Expect = 7e-10
Identities = 47/158 (29%), Positives = 72/158 (44%), Gaps = 8/158 (5%)
Query: 9 LREAIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATA 68
L A G L +V+ +L+R N+ + + LH AA G + ++L+Q + A
Sbjct: 408 LHVASFMGHLPIVKNLLQRGAS--PNVSNVKVETPLHMAARAGHTEVAKYLLQ--NKAKV 463
Query: 69 MLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCL 128
K D T +H A G V LLL E N ++ P+HIA R H +
Sbjct: 464 NAKAKDDQTPLHCAARIGHTNMVKLLL----ENNANPNLATTAGHTPLHIAAREGHVETV 519
Query: 129 ALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQ 166
LL+ A ++G T LHVA +YG ++ +LL+
Sbjct: 520 LALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLE 557
Score = 61.6 bits (148), Expect = 2e-09
Identities = 55/208 (26%), Positives = 93/208 (44%), Gaps = 15/208 (7%)
Query: 9 LREAIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATA 68
L A GK+ V +L+R D N NG + LH A + I + L+ G +
Sbjct: 540 LHVAAKYGKVRVAELLLER--DAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHS 597
Query: 69 MLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCL 128
++G T +H+A + + LLQ+ G + + S + P+H+A + H+ +
Sbjct: 598 --PAWNGYTPLHIAAKQNQVEVARSLLQY----GGSANAESVQGVTPLHLAAQEGHAEMV 651
Query: 129 ALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCGGATLADEQNQMGI----VAR 184
ALLL A+ L ++ G T LH+ + G + +L++ G + D +MG VA
Sbjct: 652 ALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHG--VMVDATTRMGYTPLHVAS 709
Query: 185 QVGNCDETIKKFDQFAAEIRKGVSSGSS 212
GN + +K Q A++ G S
Sbjct: 710 HYGNI-KLVKFLLQHQADVNAKTKLGYS 736
Score = 61.2 bits (147), Expect = 2e-09
Identities = 40/138 (28%), Positives = 69/138 (49%), Gaps = 10/138 (7%)
Query: 29 PDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDE 88
PD+L S G++ LH AA Y + + L+ G A+ +G T +H+A +G+
Sbjct: 199 PDVL----SKTGFTPLHIAAHYENLNVAQLLLNRG--ASVNFTPQNGITPLHIASRRGNV 252
Query: 89 QTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTG 148
V LLL + G + + + P+H A R+ H R +LL GA + + + G +
Sbjct: 253 IMVRLLL----DRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSP 308
Query: 149 LHVAMEYGAIQCLPILLQ 166
+H+A + + C+ +LLQ
Sbjct: 309 IHMAAQGDHLDCVRLLLQ 326
Score = 58.5 bits (140), Expect = 1e-08
Identities = 46/151 (30%), Positives = 71/151 (46%), Gaps = 8/151 (5%)
Query: 18 LGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDT 77
L V + +L R + N NG + LH A+ G ++ R L+ G A KT D T
Sbjct: 219 LNVAQLLLNRGASV--NFTPQNGITPLHIASRRGNVIMVRLLLDRG--AQIETKTKDELT 274
Query: 78 CIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGAD 137
+H A G + +LL H G +++ + +PIH+A + +H C+ LLLQ A+
Sbjct: 275 PLHCAARNGHVRISEILLDH----GAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAE 330
Query: 138 VTLEDEEGNTGLHVAMEYGAIQCLPILLQCG 168
+ + T LHVA G + +LL G
Sbjct: 331 IDDITLDHLTPLHVAAHCGHHRVAKVLLDKG 361
Score = 57.0 bits (136), Expect = 4e-08
Identities = 37/136 (27%), Positives = 69/136 (50%), Gaps = 8/136 (5%)
Query: 34 NIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAM-LKTYDGDTCIHLAITKGDEQTVH 92
N + NG + LH A+ G + +++L H + T G+T +H+A G ++ V
Sbjct: 39 NTCNQNGLNGLHLASKEGHV---KMVVELLHKEIILETTTKKGNTALHIAALAGQDEVVR 95
Query: 93 LLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVA 152
L+ + G N+ + S + + P+++A + NH + LL+ GA+ + E+G T L VA
Sbjct: 96 ELVNY----GANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVA 151
Query: 153 MEYGAIQCLPILLQCG 168
++ G + L+ G
Sbjct: 152 LQQGHENVVAHLINYG 167
Score = 54.7 bits (130), Expect = 2e-07
Identities = 46/191 (24%), Positives = 83/191 (43%), Gaps = 33/191 (17%)
Query: 9 LREAIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATA 68
L A+ L +V+ +L R + + NG++ LH AA + + R L+Q G A A
Sbjct: 573 LHVAVHHNNLDIVKLLLPRGGS--PHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANA 630
Query: 69 MLKTYDGDTCIHLAITKGDEQTVHLLLQH-----------------------------FL 99
++ G T +HLA +G + V LLL +
Sbjct: 631 --ESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLI 688
Query: 100 EEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAMEYGAIQ 159
+ G+ + +++ + P+H+A + + + LLQ ADV + + G + LH A + G
Sbjct: 689 KHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTD 748
Query: 160 CLPILLQCGGA 170
+ +LL+ G +
Sbjct: 749 IVTLLLKNGAS 759
Score = 52.8 bits (125), Expect = 7e-07
Identities = 46/169 (27%), Positives = 78/169 (45%), Gaps = 12/169 (7%)
Query: 9 LREAIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATA 68
L A + G+ VVR ++ ++ N S G++ L+ AA + + L++ G A
Sbjct: 82 LHIAALAGQDEVVRELVNYGANV--NAQSQKGFTPLYMAAQENHLEVVKFLLENG--ANQ 137
Query: 69 MLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCL 128
+ T DG T + +A+ +G E V L+ N + R +HIA R++ +R
Sbjct: 138 NVATEDGFTPLAVALQQGHENVVAHLI--------NYGTKGKVRLPALHIAARNDDTRTA 189
Query: 129 ALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCGGATLADEQN 177
A+LLQ + + + G T LH+A Y + +LL G + QN
Sbjct: 190 AVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQN 238
>Hs7705831 [R] KOG0504 FOG: Ankyrin repeat
Length = 518
Score = 66.2 bits (160), Expect = 6e-11
Identities = 45/130 (34%), Positives = 68/130 (51%), Gaps = 7/130 (5%)
Query: 40 GWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHLLLQHFL 99
G+ +LH AA G + I + L++ G D A T + T + LA+ G + LLLQH
Sbjct: 79 GFCALHLAASQGHWKIVQILLEAGADPNAT--TLEETTPLFLAVENGQIDVLRLLLQH-- 134
Query: 100 EEGLNLRSS-SARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAMEYGAI 158
G N+ S S W +H A ++ + LLL+ GA+ +D+ G T L VA +YG +
Sbjct: 135 --GANVNGSHSMCGWNSLHQASFQENAEIIKLLLRKGANKECQDDFGITPLFVAAQYGKL 192
Query: 159 QCLPILLQCG 168
+ L IL+ G
Sbjct: 193 ESLSILISSG 202
Score = 56.2 bits (134), Expect = 6e-08
Identities = 41/156 (26%), Positives = 77/156 (49%), Gaps = 9/156 (5%)
Query: 12 AIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLK 71
A+ G++ V+R +L+ ++ S GW+SLH A+F I + L++ G A +
Sbjct: 119 AVENGQIDVLRLLLQHGANV-NGSHSMCGWNSLHQASFQENAEIIKLLLRKG--ANKECQ 175
Query: 72 TYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALL 131
G T + +A G +++ +L+ G N+ + + P+ IA + H++C+ LL
Sbjct: 176 DDFGITPLFVAAQYGKLESLSILIS----SGANVNCQALDKATPLFIAAQEGHTKCVELL 231
Query: 132 LQCGADVTL--EDEEGNTGLHVAMEYGAIQCLPILL 165
L GAD L ++ +H A + G + L +L+
Sbjct: 232 LSSGADPDLYCNEDSWQLPIHAAAQMGHTKILDLLI 267
>Hs7705748 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 835
Score = 66.2 bits (160), Expect = 6e-11
Identities = 42/139 (30%), Positives = 67/139 (47%), Gaps = 6/139 (4%)
Query: 39 NGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHLLLQHF 98
NG+++LH A + + L+ G D + Y G T +H+A G + +LLQH
Sbjct: 100 NGFTALHLAVYKDNAELITSLLHSGADIQQV--GYGGLTALHIATIAGHLEAADVLLQH- 156
Query: 99 LEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAMEYGAI 158
G N+ A + P+HIA H + LLL+ GADV + E G+ LH+A G +
Sbjct: 157 ---GANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFL 213
Query: 159 QCLPILLQCGGATLADEQN 177
+L++ G + Q+
Sbjct: 214 NIAKLLMEEGSKADVNAQD 232
Score = 53.5 bits (127), Expect = 4e-07
Identities = 44/171 (25%), Positives = 75/171 (43%), Gaps = 8/171 (4%)
Query: 9 LREAIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATA 68
L A + G L +L+ ++ NI ++ LH AA+YG + R L++ G D
Sbjct: 138 LHIATIAGHLEAADVLLQHGANV--NIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNV 195
Query: 69 MLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCL 128
+ GD +HLA KG LL++ + +N + + P+H R H +
Sbjct: 196 SGEV--GDRPLHLASAKGFLNIAKLLMEEGSKADVNAQDNEDH--VPLHFCSRFGHHDIV 251
Query: 129 ALLLQCGADVT--LEDEEGNTGLHVAMEYGAIQCLPILLQCGGATLADEQN 177
LLQ +V + + G+T LH+A G + ++Q G ++N
Sbjct: 252 KYLLQSDLEVQPHVVNIYGDTPLHLACYNGKFEVAKEIIQISGTESLTKEN 302
>Hs10190676_2 [R] KOG0504 FOG: Ankyrin repeat
Length = 280
Score = 66.2 bits (160), Expect = 6e-11
Identities = 53/195 (27%), Positives = 86/195 (43%), Gaps = 7/195 (3%)
Query: 9 LREAIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATA 68
L A QG L +V+ + K+ P + N + +G + LH AA G Y + R LI L D
Sbjct: 70 LHYAAWQGHLPIVKLLAKQ-PGVSVNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNV 128
Query: 69 MLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCL 128
+ T +H+A G T LLL G ++ ++ + +H+A R+ H +
Sbjct: 129 C--SLLAQTPLHVAAETGHTSTARLLLHR----GAGKKAVTSDGYTALHLAARNGHLATV 182
Query: 129 ALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCGGATLADEQNQMGIVARQVGN 188
LL++ ADV T LH+A +G + + L+ L DEQ + G
Sbjct: 183 KLLVEEKADVLARGPLNQTALHLAAAHGHSEVVEELVSADVIDLFDEQGLSALHLAAQGR 242
Query: 189 CDETIKKFDQFAAEI 203
+T++ + A I
Sbjct: 243 HAQTVETLLRHGAHI 257
Score = 66.2 bits (160), Expect = 6e-11
Identities = 47/163 (28%), Positives = 80/163 (48%), Gaps = 7/163 (4%)
Query: 4 EPRIRLREAIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLG 63
E R + A G+ +VR +L+R D+ ++ + W LHYAA+ G I + L+
Sbjct: 32 EGRTPMHVACQHGQENIVRILLRRGVDV--SLQGKDAWLPLHYAAWQGHLPIVK-LLAKQ 88
Query: 64 HDATAMLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSN 123
+ +T DG T +HLA +G + +L+ L +N+ S A+ P+H+A +
Sbjct: 89 PGVSVNAQTLDGRTPLHLAAQRGHYRVARILID--LCSDVNVCSLLAQ--TPLHVAAETG 144
Query: 124 HSRCLALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQ 166
H+ LLL GA +G T LH+A G + + +L++
Sbjct: 145 HTSTARLLLHRGAGKKAVTSDGYTALHLAARNGHLATVKLLVE 187
Score = 53.5 bits (127), Expect = 4e-07
Identities = 37/126 (29%), Positives = 61/126 (48%), Gaps = 7/126 (5%)
Query: 41 WSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHLLLQHFLE 100
W++LH+AA G R L++ +A+ ++G T +H+A G E V +LL+
Sbjct: 1 WTALHFAAQNGDESSTRLLLE--KNASVNEVDFEGRTPMHVACQHGQENIVRILLR---- 54
Query: 101 EGLNLRSSSARRWAPIHIACRSNHSRCLALLL-QCGADVTLEDEEGNTGLHVAMEYGAIQ 159
G+++ W P+H A H + LL Q G V + +G T LH+A + G +
Sbjct: 55 RGVDVSLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQRGHYR 114
Query: 160 CLPILL 165
IL+
Sbjct: 115 VARILI 120
>Hs7662406 [R] KOG0504 FOG: Ankyrin repeat
Length = 692
Score = 65.9 bits (159), Expect = 8e-11
Identities = 55/182 (30%), Positives = 88/182 (48%), Gaps = 12/182 (6%)
Query: 6 RIRLREAIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHD 65
R L A +G L VV+ +LK DL ++ ++LH A G I LI H+
Sbjct: 43 RTPLHLAANKGHLPVVQILLKAGCDL--DVQDDGDQTALHRATVVGNTEIIAALI---HE 97
Query: 66 ATAM-LKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNH 124
A+ + DG+T +H A G Q+ LL++ G N+ + + +H+AC+++H
Sbjct: 98 GCALDRQDKDGNTALHEASWHGFSQSAKLLVK----AGANVLAKNKAGNTALHLACQNSH 153
Query: 125 SRCLALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCGGATLADEQNQMGIVAR 184
S+ +LL G+ L++ G+T LHVA Y + + +LL E+NQ G A
Sbjct: 154 SQSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLSIIRLLLT--AFCSVHEKNQAGDTAL 211
Query: 185 QV 186
V
Sbjct: 212 HV 213
Score = 53.1 bits (126), Expect = 5e-07
Identities = 38/133 (28%), Positives = 62/133 (46%), Gaps = 6/133 (4%)
Query: 39 NGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHLLLQHF 98
+G ++LH A+++G + L++ G A + K G+T +HLA Q+ +LL
Sbjct: 107 DGNTALHEASWHGFSQSAKLLVKAG--ANVLAKNKAGNTALHLACQNSHSQSTRVLLLAG 164
Query: 99 LEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAMEYGAI 158
L + +H+A R NH + LLL V +++ G+T LHVA
Sbjct: 165 SRADLKNNAGDTC----LHVAARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHK 220
Query: 159 QCLPILLQCGGAT 171
+ ILL+ G T
Sbjct: 221 KVAKILLEAGADT 233
Score = 50.8 bits (120), Expect = 3e-06
Identities = 40/148 (27%), Positives = 64/148 (43%), Gaps = 8/148 (5%)
Query: 40 GWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHLLLQHFL 99
G ++LH A R L+ G + A LK GDTC+H+A + LLL F
Sbjct: 141 GNTALHLACQNSHSQSTRVLLLAG--SRADLKNNAGDTCLHVAARYNHLSIIRLLLTAFC 198
Query: 100 EEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAMEYGAIQ 159
++ + +H+A NH + +LL+ GAD T+ + G T L A + +
Sbjct: 199 ----SVHEKNQAGDTALHVAAALNHKKVAKILLEAGADTTIVNNAGQTPLETARYHNNPE 254
Query: 160 CLPILLQC--GGATLADEQNQMGIVARQ 185
+L + G + D + VAR+
Sbjct: 255 VALLLTKAPQGSVSAGDTPSSEQAVARK 282
>7301236 [T] KOG0507 CASK-interacting adaptor protein (caskin) and related
proteins with ankyrin repeats and SAM domain
Length = 863
Score = 65.9 bits (159), Expect = 8e-11
Identities = 41/133 (30%), Positives = 64/133 (47%), Gaps = 3/133 (2%)
Query: 34 NIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHL 93
N NG++SLH+A G I R L L H+A + G T + LA G + V +
Sbjct: 43 NCQDMNGYTSLHHACLNGHSNIVRLL--LSHNALLDVPDIRGSTPLFLAAWAGHQDIVKM 100
Query: 94 LLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAM 153
LL H G N + + P+H + H+ +A+LL GAD + + T L +A
Sbjct: 101 LLMHS-PTGANPNAQTIENETPLHSGAQHGHNAVVAILLSYGADPAIRNNSFQTALDLAA 159
Query: 154 EYGAIQCLPILLQ 166
++G +Q + LL+
Sbjct: 160 QFGRLQVVQTLLR 172
>Hs21264330_2 [R] KOG0504 FOG: Ankyrin repeat
Length = 500
Score = 65.1 bits (157), Expect = 1e-10
Identities = 43/154 (27%), Positives = 75/154 (47%), Gaps = 7/154 (4%)
Query: 16 GKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDG 75
G G+V +L P++ ++ G++ LH+A+ G L R ++ K DG
Sbjct: 122 GASGIVE-VLTEVPNIDVTATNSQGFTLLHHASLKGHALAVRKILARARQLVDAKKE-DG 179
Query: 76 DTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCG 135
T +HLA + +L++ E ++ + + +P+H+A + H + LL+ G
Sbjct: 180 FTALHLAALNNHREVAQILIR---EGRCDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAG 236
Query: 136 ADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCGG 169
V EDEEG+T LHVA++ Q LP++ G
Sbjct: 237 CSVNAEDEEGDTALHVALQ--RHQLLPLVADGAG 268
>Hs18254474 [R] KOG0504 FOG: Ankyrin repeat
Length = 323
Score = 64.3 bits (155), Expect = 2e-10
Identities = 55/234 (23%), Positives = 100/234 (42%), Gaps = 9/234 (3%)
Query: 6 RIRLREAIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHD 65
R L EA QG+L ++ ++ + ++ N+ + N SSLH A G + L++ G
Sbjct: 66 RSPLHEAAAQGRLLALKTLIAQGVNV--NLVTINRVSSLHEACLGGHVACAKALLENGAH 123
Query: 66 ATAMLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHS 125
+ T G T + A G V++LL+ + L + +S PIH A + H
Sbjct: 124 VNGV--TVHGATPLFNACCSGSAACVNVLLEFGAKAQLEVHLAS-----PIHEAVKRGHR 176
Query: 126 RCLALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCGGATLADEQNQMGIVARQ 185
C+ +LL ++ E + T L+VA Y + C+ LL+ G + + + A
Sbjct: 177 ECMEILLANNVNIDHEVPQLGTPLYVACTYQRVDCVKKLLELGASVDHGQWLDTPLHAAA 236
Query: 186 VGNCDETIKKFDQFAAEIRKGVSSGSSTVPIGTPDIAASKTFLGGNNGPLSPEL 239
+ E I + A +++ + G S + + P + + L P +L
Sbjct: 237 RQSNVEVIHLLTDYGANLKRRNAQGKSALDLAAPKSSVEQALLLREGPPALSQL 290
>Hs13899329 [R] KOG0504 FOG: Ankyrin repeat
Length = 854
Score = 63.9 bits (154), Expect = 3e-10
Identities = 53/175 (30%), Positives = 89/175 (50%), Gaps = 9/175 (5%)
Query: 11 EAIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGH-DATAM 69
+A G L ++ +L + +++ D++ G + LH AA +G + L+ G D TA
Sbjct: 76 DASATGHLACLQWLLSQGGCRVQDKDNS-GATVLHLAARFGHPEVVNWLLHHGGGDPTAA 134
Query: 70 LKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLA 129
T G IH A KGD ++ LL++H+ EG+N ++ + P+++AC+ H
Sbjct: 135 --TDMGALPIHYAAAKGDFPSLRLLVEHY-PEGVNAQTKNGA--TPLYLACQEGHLEVTQ 189
Query: 130 LLLQ-CGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCGGATLADEQNQMGIVA 183
L+Q CGAD +G T LH A + G + L+ C +L+ EQ++ G A
Sbjct: 190 YLVQECGADPHARAHDGMTPLHAAAQMGHSPVIVWLVSCTDVSLS-EQDKDGATA 243
Score = 51.2 bits (121), Expect = 2e-06
Identities = 54/220 (24%), Positives = 97/220 (43%), Gaps = 16/220 (7%)
Query: 12 AIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQ-LGHDATAML 70
A +G +R +++ +P+ + N + NG + L+ A G + ++L+Q G D A
Sbjct: 145 AAAKGDFPSLRLLVEHYPEGV-NAQTKNGATPLYLACQEGHLEVTQYLVQECGADPHA-- 201
Query: 71 KTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLAL 130
+ +DG T +H A G + L+ ++L +H A H++ L+
Sbjct: 202 RAHDGMTPLHAAAQMGHSPVIVWLVSC---TDVSLSEQDKDGATAMHFAASRGHTKVLSW 258
Query: 131 LLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCGGATLADEQNQMGIVARQV---- 186
LL G +++ D G T LH A E G ++C IL+ GA L D +++ G A +
Sbjct: 259 LLLHGGEISA-DLWGGTPLHDAAENGELECCQILV-VNGAEL-DVRDRDGYTAADLSDFN 315
Query: 187 --GNCDETIKKFDQFAAEIRKGVSSGSSTVPIGTPDIAAS 224
+C ++ + + E R S+ + PD S
Sbjct: 316 GHSHCTRYLRTVENLSVEHRVLSRDPSAELEAKQPDSGMS 355
>7304338 [M] KOG4177 Ankyrin
Length = 1526
Score = 63.9 bits (154), Expect = 3e-10
Identities = 41/133 (30%), Positives = 67/133 (49%), Gaps = 6/133 (4%)
Query: 34 NIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHL 93
N + NG ++LH AA G IC L++ G K G+T +H+A G ++
Sbjct: 44 NSCNANGLNALHLAAKDGYVDICCELLRRGIKIDNATKK--GNTALHIASLAGQHDVINQ 101
Query: 94 LLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAM 153
L+ + N+ S + P+++A + NH C LL GA+ +L E+G T L VAM
Sbjct: 102 LILY----NANVNVQSLNGFTPLYMAAQENHDNCCRTLLANGANPSLSTEDGFTPLAVAM 157
Query: 154 EYGAIQCLPILLQ 166
+ G + + +LL+
Sbjct: 158 QQGHDKIVAVLLE 170
Score = 62.0 bits (149), Expect = 1e-09
Identities = 48/151 (31%), Positives = 76/151 (49%), Gaps = 8/151 (5%)
Query: 16 GKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDG 75
G + V++ +L++ +L + NG S+LH AA G + HL+ L + A T D
Sbjct: 288 GHVEVIKHLLQQNAPILTK--TKNGLSALHMAA-QGEHDEAAHLL-LDNKAPVDEVTVDY 343
Query: 76 DTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCG 135
T +H+A G + LLL + N + + + P+HIAC+ N + + LL++ G
Sbjct: 344 LTALHVAAHCGHVKVAKLLLDY----KANPNARALNGFTPLHIACKKNRIKMVELLIKHG 399
Query: 136 ADVTLEDEEGNTGLHVAMEYGAIQCLPILLQ 166
A++ E G T LHVA G I + LLQ
Sbjct: 400 ANIGATTESGLTPLHVASFMGCINIVIYLLQ 430
Score = 62.0 bits (149), Expect = 1e-09
Identities = 53/203 (26%), Positives = 91/203 (44%), Gaps = 34/203 (16%)
Query: 16 GKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDG 75
G + ++ +L+ ++ N S + +S+LH AA G+ I + L++ G + A+ K G
Sbjct: 485 GNINIIMLLLQHGAEI--NAQSNDKYSALHIAAKEGQENIVQVLLENGAENNAVTKK--G 540
Query: 76 DTCIHLAITKGDEQTVHLLLQH-----------------------------FLEEGLNLR 106
T +HLA G + V +LLQ+ L+ G +
Sbjct: 541 FTPLHLACKYGKQNVVQILLQNGASIDFQGKNDVTPLHVATHYNNPSIVELLLKNGSSPN 600
Query: 107 SSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQ 166
+ IHIAC+ N+ LLQ GADV + + G + LH+A + G + + +LL+
Sbjct: 601 LCARNGQCAIHIACKKNYLEIAMQLLQHGADVNIISKSGFSPLHLAAQGGNVDMVQLLLE 660
Query: 167 CGGATLADEQNQMGI-VARQVGN 188
G + A + + VA Q G+
Sbjct: 661 YGVISAAAKNGLTPLHVAAQEGH 683
Score = 60.1 bits (144), Expect = 4e-09
Identities = 48/174 (27%), Positives = 78/174 (44%), Gaps = 7/174 (4%)
Query: 40 GWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHLLLQHFL 99
G + LH A+ G I L+Q G + A ++ D + +H+A +G E V +LL
Sbjct: 474 GQTPLHVASRLGNINIIMLLLQHGAEINA--QSNDKYSALHIAAKEGQENIVQVLL---- 527
Query: 100 EEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAMEYGAIQ 159
E G + + + + P+H+AC+ + +LLQ GA + + + T LHVA Y
Sbjct: 528 ENGAENNAVTKKGFTPLHLACKYGKQNVVQILLQNGASIDFQGKNDVTPLHVATHYNNPS 587
Query: 160 CLPILLQCGGA-TLADEQNQMGIVARQVGNCDETIKKFDQFAAEIRKGVSSGSS 212
+ +LL+ G + L Q I N E + Q A++ SG S
Sbjct: 588 IVELLLKNGSSPNLCARNGQCAIHIACKKNYLEIAMQLLQHGADVNIISKSGFS 641
Score = 58.9 bits (141), Expect = 1e-08
Identities = 40/127 (31%), Positives = 65/127 (50%), Gaps = 8/127 (6%)
Query: 39 NGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHL-LLQH 97
NG + LH AA G L+ + L++ H A +T +G T +H+A G HL L++
Sbjct: 670 NGLTPLHVAAQEGHVLVSQILLE--HGANISERTRNGYTPLHMAAHYG-----HLDLVKF 722
Query: 98 FLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAMEYGA 157
F+E ++ SS + P+H A + H + LLL+ A+ ++GNT LH+A G
Sbjct: 723 FIENDADIEMSSNIGYTPLHQAAQQGHIMIINLLLRHKANPNALTKDGNTALHIASNLGY 782
Query: 158 IQCLPIL 164
+ + L
Sbjct: 783 VTVMESL 789
Score = 58.2 bits (139), Expect = 2e-08
Identities = 41/149 (27%), Positives = 73/149 (48%), Gaps = 9/149 (6%)
Query: 18 LGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDT 77
L + ++L+ D+ NI S +G+S LH AA G + + L++ G + A +G T
Sbjct: 619 LEIAMQLLQHGADV--NIISKSGFSPLHLAAQGGNVDMVQLLLEYGVISAA---AKNGLT 673
Query: 78 CIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGAD 137
+H+A +G +LL+H G N+ + + P+H+A H + ++ AD
Sbjct: 674 PLHVAAQEGHVLVSQILLEH----GANISERTRNGYTPLHMAAHYGHLDLVKFFIENDAD 729
Query: 138 VTLEDEEGNTGLHVAMEYGAIQCLPILLQ 166
+ + G T LH A + G I + +LL+
Sbjct: 730 IEMSSNIGYTPLHQAAQQGHIMIINLLLR 758
Score = 57.8 bits (138), Expect = 2e-08
Identities = 50/155 (32%), Positives = 72/155 (46%), Gaps = 10/155 (6%)
Query: 34 NIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHL 93
N + NG++ LH A R + LI+ H A T G T +H+A G V
Sbjct: 370 NARALNGFTPLHIACKKNRIKMVELLIK--HGANIGATTESGLTPLHVASFMGCINIVIY 427
Query: 94 LLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAM 153
LLQH L + R P+H+A R+N + + +LL+ A V EG T LHVA
Sbjct: 428 LLQHEASADL----PTIRGETPLHLAARANQADIIRILLR-SAKVDAIAREGQTPLHVAS 482
Query: 154 EYGAIQCLPILLQCG---GATLADEQNQMGIVARQ 185
G I + +LLQ G A D+ + + I A++
Sbjct: 483 RLGNINIIMLLLQHGAEINAQSNDKYSALHIAAKE 517
Score = 57.8 bits (138), Expect = 2e-08
Identities = 40/132 (30%), Positives = 65/132 (48%), Gaps = 10/132 (7%)
Query: 34 NIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHL 93
N+ S NG++ L+ AA CR L+ G A L T DG T + +A+ +G ++ V +
Sbjct: 110 NVQSLNGFTPLYMAAQENHDNCCRTLLANG--ANPSLSTEDGFTPLAVAMQQGHDKIVAV 167
Query: 94 LLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAM 153
LL++ + + L + +HIA + N LLLQ + + + G T LH+A
Sbjct: 168 LLENDVRGKVRLPA--------LHIAAKKNDVNAAKLLLQHDPNADIVSKSGFTPLHIAA 219
Query: 154 EYGAIQCLPILL 165
YG + +LL
Sbjct: 220 HYGNVDIATLLL 231
Score = 51.2 bits (121), Expect = 2e-06
Identities = 45/160 (28%), Positives = 74/160 (46%), Gaps = 9/160 (5%)
Query: 9 LREAIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATA 68
L A GK VV+ +L+ + + N + LH A Y I L++ G ++
Sbjct: 544 LHLACKYGKQNVVQILLQNGASI--DFQGKNDVTPLHVATHYNNPSIVELLLKNG--SSP 599
Query: 69 MLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCL 128
L +G IH+A K + LLQH G ++ S ++P+H+A + + +
Sbjct: 600 NLCARNGQCAIHIACKKNYLEIAMQLLQH----GADVNIISKSGFSPLHLAAQGGNVDMV 655
Query: 129 ALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCG 168
LLL+ G ++ + G T LHVA + G + ILL+ G
Sbjct: 656 QLLLEYGV-ISAAAKNGLTPLHVAAQEGHVLVSQILLEHG 694
Score = 50.1 bits (118), Expect = 5e-06
Identities = 45/163 (27%), Positives = 72/163 (43%), Gaps = 8/163 (4%)
Query: 42 SSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEE 101
++LH AA G + + L L + A + +G T +H+A K + V LL++H
Sbjct: 345 TALHVAAHCGHVKVAKLL--LDYKANPNARALNGFTPLHIACKKNRIKMVELLIKH---- 398
Query: 102 GLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCL 161
G N+ +++ P+H+A + LLQ A L G T LH+A +
Sbjct: 399 GANIGATTESGLTPLHVASFMGCINIVIYLLQHEASADLPTIRGETPLHLAARANQADII 458
Query: 162 PILLQCGGATLADEQNQMGI-VARQVGNCDETIKKFDQFAAEI 203
ILL+ + Q + VA ++GN + I Q AEI
Sbjct: 459 RILLRSAKVDAIAREGQTPLHVASRLGNIN-IIMLLLQHGAEI 500
>Hs8923104 [R] KOG0504 FOG: Ankyrin repeat
Length = 420
Score = 63.5 bits (153), Expect = 4e-10
Identities = 47/161 (29%), Positives = 69/161 (42%), Gaps = 6/161 (3%)
Query: 6 RIRLREAIVQGKLGVVRRILKRWPDL-LENIDSTNGWSSLHYAAFYGRYLICRHLIQLGH 64
R L A G L + +L++ P L + DS GW+ +H+AA +G+ L++ G
Sbjct: 23 RFPLHRACRDGDLATLCSLLQQTPHAHLASEDSFYGWTPVHWAAHFGKLECLVQLVRAGA 82
Query: 65 DATAMLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNH 124
Y T H+A G Q + L+Q G N+ PIH A RS
Sbjct: 83 TLNVSTTRY-AQTPAHIAAFGGHPQCLVWLIQ----AGANINKPDCEGETPIHKAARSGS 137
Query: 125 SRCLALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILL 165
C++ L+ GA V L + G T +A G +C LL
Sbjct: 138 LECISALVANGAHVDLRNASGLTAADIAQTQGFQECAQSLL 178
>Hs14149803 [U] KOG2319 Vacuolar assembly/sorting protein VPS9
Length = 1050
Score = 63.5 bits (153), Expect = 4e-10
Identities = 52/176 (29%), Positives = 78/176 (43%), Gaps = 11/176 (6%)
Query: 34 NIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHL 93
N+ S +G S LH AA +GR + R L++ H A A + D +HLA +G Q V
Sbjct: 738 NVTSQDGSSPLHVAALHGRADLIRLLLK--HGANAGARNADQAVPLHLACQQGHFQVVKC 795
Query: 94 LLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAM 153
LL + S + P+ AC H +ALLLQ GA + + +GNT LH A+
Sbjct: 796 LLDSNAKPNKKDLSGNT----PLIYACSGGHHELVALLLQHGASINASNNKGNTALHEAV 851
Query: 154 EYGAIQCLPILLQCGGATLADEQNQMGIVARQVGNCDETIKKFDQFAAEIRKGVSS 209
+ + +LL G + + Q R +C E K + + V+S
Sbjct: 852 IEKHVFVVELLLLHGASVQVLNKRQ-----RTAVDCAEQNSKIMELLQVVPSCVAS 902
Score = 58.2 bits (139), Expect = 2e-08
Identities = 53/215 (24%), Positives = 93/215 (42%), Gaps = 13/215 (6%)
Query: 40 GWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHLLLQHFL 99
G + LH AA G+ + L+ G A Y G T +HLA KG Q+V LLL H+
Sbjct: 463 GHTPLHVAAVCGQASLIDLLVSKG--AMVNATDYHGATPLHLACQKG-YQSVTLLLLHY- 518
Query: 100 EEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGAD---VTLEDEEGNTGLHVAMEYG 156
+ ++ ++ P+H+AC H C+ L+ + + + +E+G+T LH+A +G
Sbjct: 519 KASAEVQDNNGN--TPLHLACTYGHEDCVKALVYYDVESCRLDIGNEKGDTPLHIAARWG 576
Query: 157 AIQCLPILLQCGGATLADEQNQMGIVARQVGNCDETIKKFDQFAAEIRKGVSSGSSTVPI 216
+ LLQ G +T + QN++ + + + + + + SS P+
Sbjct: 577 YQGVIETLLQNGAST--EIQNRLKETPLKCALNSKILSVMEAYHLSFER--RQKSSEAPV 632
Query: 217 GTPDIAASKTFLGGNNGPLSPELRGRRSIKDLNDY 251
+P + + S G R + DY
Sbjct: 633 QSPQRSVDSISQESSTSSFSSMSAGSRQEETKKDY 667
Score = 55.5 bits (132), Expect = 1e-07
Identities = 46/177 (25%), Positives = 76/177 (41%), Gaps = 27/177 (15%)
Query: 8 RLREAIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDAT 67
+L A+ G L +VR +L+ + LE+ + T + + C L Q A
Sbjct: 672 KLLRAVADGDLEMVRYLLEWTEEDLEDAEDTVSAADPEF---------CHPLCQCPKCAP 722
Query: 68 AMLK--------------TYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRW 113
A + + DG + +H+A G + LLL+H G N + +A +
Sbjct: 723 AQKRLAKVPASGLGVNVTSQDGSSPLHVAALHGRADLIRLLLKH----GANAGARNADQA 778
Query: 114 APIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCGGA 170
P+H+AC+ H + + LL A +D GNT L A G + + +LLQ G +
Sbjct: 779 VPLHLACQQGHFQVVKCLLDSNAKPNKKDLSGNTPLIYACSGGHHELVALLLQHGAS 835
>Hs13376003 [M] KOG4177 Ankyrin
Length = 274
Score = 63.5 bits (153), Expect = 4e-10
Identities = 43/163 (26%), Positives = 79/163 (48%), Gaps = 6/163 (3%)
Query: 4 EPRIRLREAIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLG 63
+ ++++ A+ G + VR++L++ N NGW+ LH++A G+ R ++ G
Sbjct: 13 QEELQIQAAVAAGDVHTVRKMLEQ--GYSPNGRDANGWTLLHFSAARGKERCVRVFLEHG 70
Query: 64 HDATAMLKTYDGDTCIHLAITKGDEQTVHLLLQ-HFLEEGLNLRSSSARRWAPIHIACRS 122
D T G T +H A G + L+L+ + + +N +S+ W P+H+A
Sbjct: 71 ADPTVK-DLIGGFTALHYAAMHGRARIARLMLESEYRSDIINAKSNDG--WTPLHVAAHY 127
Query: 123 NHSRCLALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILL 165
+ LLL+ A+V ++G T L +A+ C+ ILL
Sbjct: 128 GRDSFVRLLLEFKAEVDPLSDKGTTPLQLAIIREKSSCVKILL 170
>7301359 [M] KOG4177 Ankyrin
Length = 1181
Score = 62.8 bits (151), Expect = 7e-10
Identities = 50/178 (28%), Positives = 78/178 (43%), Gaps = 23/178 (12%)
Query: 7 IRLREAIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDA 66
+ L A G V ++K ++ N+ ++ LH AA G+Y IC+ L++ H A
Sbjct: 555 VPLHNACSYGHYEVTELLVKHGANV--NVSDLWKFTPLHEAAAKGKYDICKLLLK--HGA 610
Query: 67 TAMLKTYDGDTCIHLAITKGDEQTVHLL-----------------LQHFLE-EGLNLRSS 108
M K DG T L + + D LL +Q + E +N R +
Sbjct: 611 DPMKKNRDGATPADL-VKESDHDVAELLRGPSALLDAAKKGNLARVQRLVTPESINCRDA 669
Query: 109 SARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQ 166
R P+H+A N+ C LL+ GADV +D+ G LH A YG + +L++
Sbjct: 670 QGRNSTPLHLAAGYNNFECAEYLLENGADVNAQDKGGLIPLHNASSYGHLDIAALLIK 727
Score = 55.5 bits (132), Expect = 1e-07
Identities = 51/183 (27%), Positives = 79/183 (42%), Gaps = 33/183 (18%)
Query: 16 GKLGVVRRILKRWPDLLENIDSTNGWS--SLHYAAFYGRYLICRHLIQLGHDATAMLKTY 73
G VVR +LK + ++T+ W+ LH AA G+ +C L+Q H A ++
Sbjct: 101 GHAEVVRLLLKAGA----SPNTTDNWNYTPLHEAASKGKVDVCLALLQ--HGANHTIRNS 154
Query: 74 DGDTCIHLAITKGDEQTVHLLLQHFLEEGL---------------------NLRSSSARR 112
+ T + LA DE T +L + ++ L N +S RR
Sbjct: 155 EQKTPLELA----DEATRPVLTGEYRKDELLEAARSGAEDRLLALLTPLNVNCHASDGRR 210
Query: 113 WAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCGGATL 172
P+H+A N + +LL GADV +D+ G LH A YG +L+Q G
Sbjct: 211 STPLHLAAGYNRIGIVEILLANGADVHAKDKGGLVPLHNACSYGHFDVTKLLIQAGANVN 270
Query: 173 ADE 175
A++
Sbjct: 271 AND 273
>Hs4885087 [R] KOG0504 FOG: Ankyrin repeat
Length = 446
Score = 62.4 bits (150), Expect = 9e-10
Identities = 41/135 (30%), Positives = 64/135 (47%), Gaps = 5/135 (3%)
Query: 74 DGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQ 133
DGDT +H+A+ +G+ VH L+ F + G L + R P+H+A + + LL+
Sbjct: 126 DGDTPLHIAVVQGNLPAVHRLVNLFQQGGRELDIYNNLRQTPLHLAVITTLPSVVRLLVT 185
Query: 134 CGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCG--GATLADEQNQMGIVARQVG---N 188
GA D G T H+A E+ + CL LL G + +N G+ A V
Sbjct: 186 AGASPMALDRHGQTAAHLACEHRSPTCLRALLDSAAPGTLDLEARNYDGLTALHVAVNTE 245
Query: 189 CDETIKKFDQFAAEI 203
C ET++ + A+I
Sbjct: 246 CQETVQLLLERGADI 260
>Hs20472035 [R] KOG0504 FOG: Ankyrin repeat
Length = 361
Score = 61.2 bits (147), Expect = 2e-09
Identities = 52/184 (28%), Positives = 86/184 (46%), Gaps = 13/184 (7%)
Query: 6 RIRLREAIVQGKLGVVRRILKRW---PDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQL 62
R L A + G L V+ +LKR PD +N G ++L A G + R L+
Sbjct: 172 RTPLHTAAMHGHLEAVKVLLKRCQYEPDYRDNC----GVTALMDAIQCGHIDVARLLLD- 226
Query: 63 GHDATAMLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRS 122
H A + G +H A G ++ + L+ L +++R++S A +H A +
Sbjct: 227 EHGACLSAEDSLGAQALHRAAVTGQDEAIRFLVSE-LGVDVDVRATSTHLTA-LHYAAKE 284
Query: 123 NHSRCLALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCGGATLADEQNQMGIV 182
H+ + LL GAD+ +DE+ + LH+A + C LLQ G L D ++ G +
Sbjct: 285 GHTSTIQTLLSLGADINSKDEKNRSALHLACAGQHLACAKFLLQSG---LKDSEDITGTL 341
Query: 183 ARQV 186
A+Q+
Sbjct: 342 AQQL 345
>CE26238_1 [M] KOG4177 Ankyrin
Length = 1294
Score = 60.8 bits (146), Expect = 3e-09
Identities = 53/181 (29%), Positives = 83/181 (45%), Gaps = 8/181 (4%)
Query: 18 LGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDT 77
L +V +I +++N S NGWS L A G + I L H A + G T
Sbjct: 818 LAMVNKIGAGAVQIVQNKQSKNGWSPLLEACARGHSGVAN--ILLKHHARIDVFDEMGRT 875
Query: 78 CIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQ-CGA 136
+HLA G VHLLLQH + +N +S + AP+H+A + H + + +L+Q GA
Sbjct: 876 ALHLAAFNGHLSLVHLLLQH--KAFVNSKSKTGE--APLHLAAQHGHVKVVNVLVQDHGA 931
Query: 137 DVTLEDEEGNTGLHVAMEYGAIQCLPILLQCGGATLA-DEQNQMGIVARQVGNCDETIKK 195
+ + T LH A ++G + LL G A D++ Q + + + +K
Sbjct: 932 ALEAITLDNQTALHFAAKFGQLAVSQTLLALGANPNARDDKGQTPLHLAAENDFPDVVKL 991
Query: 196 F 196
F
Sbjct: 992 F 992
Score = 57.4 bits (137), Expect = 3e-08
Identities = 43/146 (29%), Positives = 68/146 (46%), Gaps = 7/146 (4%)
Query: 9 LREAIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATA 68
L EA +G GV +LK + ++ G ++LH AAF G + L+Q H A
Sbjct: 844 LLEACARGHSGVANILLKHHARI--DVFDEMGRTALHLAAFNGHLSLVHLLLQ--HKAFV 899
Query: 69 MLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCL 128
K+ G+ +HLA G + V++L+Q + G L + + +H A +
Sbjct: 900 NSKSKTGEAPLHLAAQHGHVKVVNVLVQ---DHGAALEAITLDNQTALHFAAKFGQLAVS 956
Query: 129 ALLLQCGADVTLEDEEGNTGLHVAME 154
LL GA+ D++G T LH+A E
Sbjct: 957 QTLLALGANPNARDDKGQTPLHLAAE 982
Score = 53.9 bits (128), Expect = 3e-07
Identities = 37/138 (26%), Positives = 65/138 (46%), Gaps = 10/138 (7%)
Query: 40 GWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHLLLQHFL 99
G++ LH AA G + R L+ G A T + +HLA +G V +LL
Sbjct: 1158 GFTPLHLAAQSGHDSLVRMLLNQGVQVDATSTTMNVIP-LHLAAQQGHIAVVGMLLSRST 1216
Query: 100 EEGLNLRSSSARRW---APIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAMEYG 156
++ A+ W P+H+A ++ H ++LL+ G+++ + D+ G TGLH A G
Sbjct: 1217 QQ------QHAKDWRGRTPLHLAAQNGHYEMVSLLIAQGSNINVMDQNGWTGLHFATRAG 1270
Query: 157 AIQCLPILLQCGGATLAD 174
+ + + + LA+
Sbjct: 1271 HLSVVKLFIDSSADPLAE 1288
>Hs13376842 [M] KOG4177 Ankyrin
Length = 1166
Score = 60.5 bits (145), Expect = 3e-09
Identities = 52/185 (28%), Positives = 80/185 (43%), Gaps = 24/185 (12%)
Query: 7 IRLREAIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDA 66
+ L A G V ++K + N+ ++ LH AA G+Y IC+ L+Q G D
Sbjct: 561 VPLHNACSYGHYEVAELLVKH--GAVVNVADLWKFTPLHEAAAKGKYEICKLLLQHGADP 618
Query: 67 TAMLKTYDGDTCIHLA---------ITKGDEQTVHLLLQHFLE--------EGLNLRSSS 109
T K DG+T + L + +GD + + L + +N R +
Sbjct: 619 TK--KNRDGNTPLDLVKDGDTDIQDLLRGDAALLDAAKKGCLARVKKLSSPDNVNCRDTQ 676
Query: 110 ARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQ--- 166
R P+H+A N+ LLQ GADV +D+ G LH A YG + +L++
Sbjct: 677 GRHSTPLHLAAGYNNLEVAEYLLQHGADVNAQDKGGLIPLHNAASYGHVDVAALLIKYNA 736
Query: 167 CGGAT 171
C AT
Sbjct: 737 CVNAT 741
Score = 58.2 bits (139), Expect = 2e-08
Identities = 52/187 (27%), Positives = 78/187 (40%), Gaps = 27/187 (14%)
Query: 7 IRLREAIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDA 66
I L A G VV +L+ D N ++ LH AA G+ +C L+Q H A
Sbjct: 93 IPLHNACSFGHAEVVNLLLRHGAD--PNARDNWNYTPLHEAAIKGKIDVCIVLLQ--HGA 148
Query: 67 TAMLKTYDGDTCIHLA--------------------ITKGDEQTVHLLLQHFLEEGLNLR 106
++ DG T + LA G+E+ + LL +N
Sbjct: 149 EPTIRNTDGRTALDLADPSAKAVLTGEYKKDELLESARSGNEEKMMALLTPL---NVNCH 205
Query: 107 SSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQ 166
+S R+ P+H+A N + + LLLQ GADV +D+ LH A YG + +L++
Sbjct: 206 ASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHAKDKGDLVPLHNACSYGHYEVTELLVK 265
Query: 167 CGGATLA 173
G A
Sbjct: 266 HGACVNA 272
Score = 52.0 bits (123), Expect = 1e-06
Identities = 45/151 (29%), Positives = 75/151 (48%), Gaps = 10/151 (6%)
Query: 4 EPRIR-LREAIVQGKLGVVRRILKRWPDLLENIDSTNGWSS-LHYAAFYGRYLICRHLIQ 61
EP R L EA G + V+R++ P+ + + D+ S+ LH+AA +GR + +L+Q
Sbjct: 22 EPAARELFEACRNGDVERVKRLVT--PEKVNSRDTAGRKSTPLHFAAGFGRKDVVEYLLQ 79
Query: 62 LGHDATAMLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACR 121
G A + G +H A + G + V+LLL+H G + + + P+H A
Sbjct: 80 NG--ANVQARDDGGLIPLHNACSFGHAEVVNLLLRH----GADPNARDNWNYTPLHEAAI 133
Query: 122 SNHSRCLALLLQCGADVTLEDEEGNTGLHVA 152
+LLQ GA+ T+ + +G T L +A
Sbjct: 134 KGKIDVCIVLLQHGAEPTIRNTDGRTALDLA 164
Score = 51.6 bits (122), Expect = 2e-06
Identities = 45/144 (31%), Positives = 71/144 (49%), Gaps = 13/144 (9%)
Query: 9 LREAIVQGKLGVVRRILKRWPDLLENIDSTNGWSS-LHYAAFYGRYLICRHLIQLGHDAT 67
L +A +G L V+++ PD + D+ S+ LH AA Y + +L+Q G D
Sbjct: 649 LLDAAKKGCLARVKKLSS--PDNVNCRDTQGRHSTPLHLAAGYNNLEVAEYLLQHGADVN 706
Query: 68 AMLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWA--PIHIACRSNHS 125
A K G +H A + G LL+++ N ++ +WA P+H A + +
Sbjct: 707 AQDK--GGLIPLHNAASYGHVDVAALLIKY------NACVNATDKWAFTPLHEAAQKGRT 758
Query: 126 RCLALLLQCGADVTLEDEEGNTGL 149
+ ALLL GAD TL+++EG T L
Sbjct: 759 QLCALLLAHGADPTLKNQEGQTPL 782
Score = 51.6 bits (122), Expect = 2e-06
Identities = 43/153 (28%), Positives = 61/153 (39%), Gaps = 27/153 (17%)
Query: 40 GWSSLHYAAFYGRYLICRHLIQLGHDATAM------------------------LKTYDG 75
G +SLH AA+ G CR L+ G D + L +
Sbjct: 433 GQTSLHRAAYCGHLQTCRLLLSYGCDPNIISLQGFTALQMGNENVQQLLQEGISLGNSEA 492
Query: 76 DTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCG 135
D + A GD +TV L + +N R R+ P+H A N + LLQ G
Sbjct: 493 DRQLLEAAKAGDVETVKKLCT---VQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHG 549
Query: 136 ADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCG 168
ADV +D+ G LH A YG + +L++ G
Sbjct: 550 ADVHAKDKGGLVPLHNACSYGHYEVAELLVKHG 582
>Hs4507613 [M] KOG4177 Ankyrin
Length = 1327
Score = 60.1 bits (144), Expect = 4e-09
Identities = 46/151 (30%), Positives = 69/151 (45%), Gaps = 22/151 (14%)
Query: 41 WSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLA---------ITKGDEQTV 91
++ LH AA G+Y IC+ L++ G D T K DG+T + L + KGD +
Sbjct: 751 FTPLHEAAAKGKYEICKLLLKHGADPTK--KNRDGNTPLDLVKEGDTDIQDLLKGDAALL 808
Query: 92 HLLLQHFLE--------EGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDE 143
+ L E +N R + R P+H+A N+ LL+ GADV +D+
Sbjct: 809 DAAKKGCLARVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDK 868
Query: 144 EGNTGLHVAMEYGAIQCLPILLQ---CGGAT 171
G LH A YG + +L++ C AT
Sbjct: 869 GGLIPLHNAASYGHVDIAALLIKYNTCVNAT 899
Score = 59.7 bits (143), Expect = 6e-09
Identities = 54/187 (28%), Positives = 79/187 (41%), Gaps = 27/187 (14%)
Query: 7 IRLREAIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDA 66
I L A G VV +L + D N ++ LH AA G+ +C L+Q H A
Sbjct: 251 IPLHNACSFGHAEVVSLLLCQGAD--PNARDNWNYTPLHEAAIKGKIDVCIVLLQ--HGA 306
Query: 67 TAMLKTYDGDTCIHLA--------------------ITKGDEQTVHLLLQHFLEEGLNLR 106
++ DG + + LA G+E+ + LL +N
Sbjct: 307 DPNIRNTDGKSALDLADPSAKAVLTGEYKKDELLEAARSGNEEKLMALLTPL---NVNCH 363
Query: 107 SSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQ 166
+S R+ P+H+A N R + LLLQ GADV +D+ G LH A YG + +LL+
Sbjct: 364 ASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLK 423
Query: 167 CGGATLA 173
G A
Sbjct: 424 HGACVNA 430
Score = 52.8 bits (125), Expect = 7e-07
Identities = 44/161 (27%), Positives = 64/161 (39%), Gaps = 27/161 (16%)
Query: 34 NIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAM------------------------ 69
N T G ++LH AA G CR L+ G D + +
Sbjct: 585 NALDTLGQTALHRAALAGHLQTCRLLLSYGSDPSIISLQGFTAAQMGNEAVQQILSESTP 644
Query: 70 LKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLA 129
++T D D + A GD +TV L + +N R R P+H A N +
Sbjct: 645 IRTSDVDYRLLEASKAGDLETVKQLCS---SQNVNCRDLEGRHSTPLHFAAGYNRVSVVE 701
Query: 130 LLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCGGA 170
LL GADV +D+ G LH A YG + +L++ G +
Sbjct: 702 YLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGAS 742
Score = 51.6 bits (122), Expect = 2e-06
Identities = 43/140 (30%), Positives = 67/140 (47%), Gaps = 12/140 (8%)
Query: 17 KLGVVRRILKRWPDLLENIDSTNGWSS--LHYAAFYGRYLICRHLIQLGHDATAMLKTYD 74
K G + R+ K N T G +S LH AA Y + +L++ G D A K
Sbjct: 812 KKGCLARVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDK--G 869
Query: 75 GDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWA--PIHIACRSNHSRCLALLL 132
G +H A + G LL+++ N ++ +WA P+H A + ++ ALLL
Sbjct: 870 GLIPLHNAASYGHVDIAALLIKY------NTCVNATDKWAFTPLHEAAQKGRTQLCALLL 923
Query: 133 QCGADVTLEDEEGNTGLHVA 152
GAD T++++EG T L +A
Sbjct: 924 AHGADPTMKNQEGQTPLDLA 943
Score = 49.3 bits (116), Expect = 8e-06
Identities = 42/144 (29%), Positives = 66/144 (45%), Gaps = 8/144 (5%)
Query: 11 EAIVQGKLGVVRRILKRWPDLLENIDSTNGWSS--LHYAAFYGRYLICRHLIQLGHDATA 68
E + + G +++ L N +++G S LH AA Y R I + L+Q G D A
Sbjct: 338 ELLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHA 397
Query: 69 MLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCL 128
K G +H A + G + LLL+H G + + ++ P+H A N
Sbjct: 398 --KDKGGLVPLHNACSYGHYEVTELLLKH----GACVNAMDLWQFTPLHEAASKNRVEVC 451
Query: 129 ALLLQCGADVTLEDEEGNTGLHVA 152
+LLL GAD TL + G + + +A
Sbjct: 452 SLLLSHGADPTLVNCHGKSAVDMA 475
>7294199_2 [R] KOG0504 FOG: Ankyrin repeat
Length = 708
Score = 60.1 bits (144), Expect = 4e-09
Identities = 47/157 (29%), Positives = 71/157 (44%), Gaps = 8/157 (5%)
Query: 9 LREAIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATA 68
L+ A G + V++ +L+ D+ I+ +G ++H+AAF + L + G D A
Sbjct: 69 LQAASQNGHIEVIQVLLRHAVDV--EIEDKDGDRAVHHAAFGDEAAVIEILAKAGADLNA 126
Query: 69 MLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCL 128
K T +H+A+ KG V LL G + + P+H A H L
Sbjct: 127 RNKRRQ--TSLHIAVNKGHLNVVKTLLTL----GCHPSLQDSEGDTPLHDAISKEHDEML 180
Query: 129 ALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILL 165
+LLL GAD+TL + G LH A G + ILL
Sbjct: 181 SLLLDFGADITLNNNNGFNALHHAALKGNPSAMKILL 217
Score = 53.9 bits (128), Expect = 3e-07
Identities = 38/140 (27%), Positives = 69/140 (49%), Gaps = 12/140 (8%)
Query: 35 IDSTNGWSSLHYAAFYGRYLICRHLI-QLGHDATAMLKTYDGDTCIHLAITKGD----EQ 89
+++ NG+++LH+AA G + L+ + K DG T +HLA E
Sbjct: 192 LNNNNGFNALHHAALKGNPSAMKILLTKTNRPWIVEEKKDDGYTALHLAALNNHVEIAEL 251
Query: 90 TVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGL 149
VH+ + + +NL+++ +H+A H + + LL+Q GAD+ + D++G+T L
Sbjct: 252 LVHMGKANMDRQNVNLQTA-------LHLAVERQHVQIVKLLVQDGADLNIPDKDGDTPL 304
Query: 150 HVAMEYGAIQCLPILLQCGG 169
H A+ + + L L G
Sbjct: 305 HEALRHHTLSQLKQLQDVEG 324
Score = 53.5 bits (127), Expect = 4e-07
Identities = 39/138 (28%), Positives = 64/138 (46%), Gaps = 6/138 (4%)
Query: 40 GWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHLLLQHFL 99
G ++L A+ G + + L++ H ++ DGD +H A GDE V ++
Sbjct: 65 GHTALQAASQNGHIEVIQVLLR--HAVDVEIEDKDGDRAVHHAAF-GDEAAV---IEILA 118
Query: 100 EEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAMEYGAIQ 159
+ G +L + + RR +HIA H + LL G +L+D EG+T LH A+ +
Sbjct: 119 KAGADLNARNKRRQTSLHIAVNKGHLNVVKTLLTLGCHPSLQDSEGDTPLHDAISKEHDE 178
Query: 160 CLPILLQCGGATLADEQN 177
L +LL G + N
Sbjct: 179 MLSLLLDFGADITLNNNN 196
>Hs7656961 [R] KOG0504 FOG: Ankyrin repeat
Length = 319
Score = 59.7 bits (143), Expect = 6e-09
Identities = 49/176 (27%), Positives = 76/176 (42%), Gaps = 20/176 (11%)
Query: 3 PEPRI--------RLREAIVQGKLGVVRRIL--KRWPDLLENIDSTNGWSSLHYAAFYGR 52
PEP I +A ++ KL VV + L K PD+ + T +LH A G
Sbjct: 110 PEPEIITEPVDVPTFLKAALENKLPVVEKFLSDKNNPDVCDEYKRT----ALHRACLEGH 165
Query: 53 YLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARR 112
I L++ G A + T IH A G+ + LLL +G + +
Sbjct: 166 LAIVEKLMEAG--AQIEFRDMLESTAIHWASRGGNLDVLKLLLN----KGAKISARDKLL 219
Query: 113 WAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCG 168
+H+A R+ H C L+ C AD+ +D EG+T LH A+ + + +L+ G
Sbjct: 220 STALHVAVRTGHYECAEHLIACEADLNAKDREGDTPLHDAVRLNRYKMIRLLIMYG 275
>At5g60070 [R] KOG0504 FOG: Ankyrin repeat
Length = 548
Score = 59.3 bits (142), Expect = 8e-09
Identities = 41/155 (26%), Positives = 78/155 (49%), Gaps = 5/155 (3%)
Query: 12 AIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLK 71
A QG+L V+R +++ P+L +D +N ++LH AA G + +L++ + A +
Sbjct: 115 AAKQGELDVLRVLMEEHPELSMTVDLSNT-TALHTAAAQGHVEVVEYLLEAAGSSLAAIA 173
Query: 72 TYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALL 131
+G T +H A G + V ++ +E R+ + P+H+A + + L
Sbjct: 174 KSNGKTALHSAARNGHAEVVKAIVA--VEPDTATRTDKKGQ-TPLHMAVKGQSIDVVVEL 230
Query: 132 LQCG-ADVTLEDEEGNTGLHVAMEYGAIQCLPILL 165
++ + + + D +GNT LHVA G I+ + +LL
Sbjct: 231 MKGHRSSLNMADSKGNTALHVATRKGRIKIVELLL 265
>Hs7706377 [R] KOG0504 FOG: Ankyrin repeat
Length = 335
Score = 57.8 bits (138), Expect = 2e-08
Identities = 43/137 (31%), Positives = 66/137 (47%), Gaps = 13/137 (9%)
Query: 76 DTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWA-------PIHIACRSNHSRCL 128
DT +H A GD QT+ LLQ EE R + W P+ IA + H C+
Sbjct: 38 DTRLHDAAYVGDLQTLRSLLQ---EESYRSRINEKSVWCCGWLPCTPLRIAATAGHGSCV 94
Query: 129 ALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCGGATLADEQNQMGIV--ARQV 186
L++ GA+V L D +G T L+VA+ G ++ ILL+ G ++ V A +V
Sbjct: 95 DFLIRKGAEVDLVDVKGQTALYVAVVNGHLESTQILLEAGADPNGSRHHRSTPVYHASRV 154
Query: 187 GNCDETIKKFDQFAAEI 203
G D +K ++ A++
Sbjct: 155 GRAD-ILKALIRYGADV 170
>Hs6601590 [R] KOG0510 Ankyrin repeat protein
Length = 1119
Score = 57.8 bits (138), Expect = 2e-08
Identities = 44/138 (31%), Positives = 66/138 (46%), Gaps = 9/138 (6%)
Query: 42 SSLHYAAFYGRYLICRHLIQLGHDATAMLKTYD--GDTCIHLAITKGDEQTVHLLLQHFL 99
S LH+AA YGR C+ L+Q D T +L D G T +HLA G ++ V LLL+
Sbjct: 448 SPLHFAASYGRINTCQRLLQDISD-TRLLNEGDLHGMTPLHLAAKNGHDKVVQLLLKKGA 506
Query: 100 EEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLE-DEEGNTGLHVAMEYGAI 158
L S W +H A +++ + ++L T DE+GNT LH A G
Sbjct: 507 -----LFLSDHNGWTALHHASMGGYTQTMKVILDTNLKCTDRLDEDGNTALHFAAREGHA 561
Query: 159 QCLPILLQCGGATLADEQ 176
+ + +LL + ++Q
Sbjct: 562 KAVALLLSHNADIVLNKQ 579
>Hs18254470 [R] KOG0504 FOG: Ankyrin repeat
Length = 429
Score = 57.8 bits (138), Expect = 2e-08
Identities = 50/204 (24%), Positives = 85/204 (41%), Gaps = 57/204 (27%)
Query: 5 PRIRLREAIVQGKLGVVRRIL------------------KRWPDLLENIDSTNGWSSLHY 46
P + +A++ G +G V RIL +RW D NI + WS
Sbjct: 54 PALAFWQAVLAGDVGCVSRILADSSTGLAPDSVFDTSDPERWRDFRFNIRALRLWSL--- 110
Query: 47 AAFYGRYLICRHLIQLGHDATAMLKTYDGD--TCIHLAITKGDEQTVHLLLQHFLEEGLN 104
TY+ + T +H+A ++G + + LLL+
Sbjct: 111 -------------------------TYEEELTTPLHVAASRGHTEVLRLLLRRRARPD-- 143
Query: 105 LRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPIL 164
S+ R A +H AC + H+ C+ +LL GAD + D++G LH+ G ++C +L
Sbjct: 144 --SAPGGRTA-LHEACAAGHTACVHVLLVAGADPNIADQDGKRPLHLCRGPGTLECAELL 200
Query: 165 LQCG----GATLADEQNQMGIVAR 184
L+ G G + +E+ + + AR
Sbjct: 201 LRFGARVDGRSEEEEETPLHVAAR 224
>7298956 [R] KOG0510 Ankyrin repeat protein
Length = 914
Score = 57.8 bits (138), Expect = 2e-08
Identities = 46/155 (29%), Positives = 67/155 (42%), Gaps = 14/155 (9%)
Query: 25 LKRWPDLLENIDST---------NGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDG 75
LKRW DL+E++ NG S+LH +AF G L+ G + K Y
Sbjct: 88 LKRW-DLIESLLEAGADLHFCDQNGISALHLSAFSGCLATLGLLVAKGLNVNLQSKCY-- 144
Query: 76 DTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCG 135
T +H A + LL+ + + + + + +H A RSN CL + + G
Sbjct: 145 -TPLHCAAFGNAAEAAKLLINNGADISKDTSKPNCEE-SLLHCAVRSNALECLQIFIAEG 202
Query: 136 ADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCGGA 170
ADV G +H+A + G IQCL LL A
Sbjct: 203 ADVNSLKPNGTNAIHLAADLGNIQCLEALLNAPNA 237
Score = 49.3 bits (116), Expect = 8e-06
Identities = 39/148 (26%), Positives = 64/148 (42%), Gaps = 3/148 (2%)
Query: 24 ILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHL-IQLGHDATAMLKTYDGDTCIHLA 82
++ D+ ++ N SL + A L C + I G D ++ +G IHLA
Sbjct: 162 LINNGADISKDTSKPNCEESLLHCAVRSNALECLQIFIAEGADVNSLKP--NGTNAIHLA 219
Query: 83 ITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLED 142
G+ Q + LL + + +H+A + C+ LLL GAD L++
Sbjct: 220 ADLGNIQCLEALLNAPNADANVRICIREKESTALHLAADEGNVECVDLLLAKGADAKLKN 279
Query: 143 EEGNTGLHVAMEYGAIQCLPILLQCGGA 170
G T LH+A ++ C+ LL+ G A
Sbjct: 280 HRGFTPLHLAARTSSLDCVESLLRNGNA 307
>Hs10835177_2 [R] KOG0504 FOG: Ankyrin repeat
Length = 427
Score = 57.8 bits (138), Expect = 2e-08
Identities = 47/165 (28%), Positives = 82/165 (49%), Gaps = 7/165 (4%)
Query: 7 IRLREAIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDA 66
I L +V+ L V ++ D + N+ + + LH A + + L++ G D
Sbjct: 11 IHLHSQLVRDLLEVTSGLIS---DDIINMRNDLYQTPLHLAVITKQEDVVEDLLRAGADL 67
Query: 67 TAMLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSR 126
+ + + G++ +HLA +G ++ + +LL+H + L L + IH+A SN
Sbjct: 68 SLLDRL--GNSVLHLAAKEGHDKVLSILLKH-KKAALLLDHPNGDGLNAIHLAMMSNSLP 124
Query: 127 CLALLLQCGADVTLEDEE-GNTGLHVAMEYGAIQCLPILLQCGGA 170
CL LL+ GADV ++++ G T LH+A+E+ I LL G A
Sbjct: 125 CLLLLVAAGADVNAQEQKSGRTALHLAVEHDNISLAGCLLLEGDA 169
>At5g13530_3 [R] KOG0504 FOG: Ankyrin repeat
Length = 332
Score = 57.8 bits (138), Expect = 2e-08
Identities = 40/136 (29%), Positives = 64/136 (46%), Gaps = 7/136 (5%)
Query: 37 STNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHLLLQ 96
+ +G S+LH A G + +++ G +A + DGD + A+ G Q VH+L++
Sbjct: 6 NADGQSALHLACRRGSAELVEAILEYG-EANVDIVDKDGDPPLVFALAAGSPQCVHVLIK 64
Query: 97 HFLEEGLNLRSSSARRWAP--IHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAME 154
+G N+RS P H+ C+ LL GAD D+EG T LH A+
Sbjct: 65 ----KGANVRSRLREGSGPSVAHVCSYHGQPDCMRELLVAGADPNAVDDEGETVLHRAVA 120
Query: 155 YGAIQCLPILLQCGGA 170
C ++L+ GG+
Sbjct: 121 KKYTDCAIVILENGGS 136
Score = 52.8 bits (125), Expect = 7e-07
Identities = 30/104 (28%), Positives = 54/104 (51%), Gaps = 6/104 (5%)
Query: 51 GRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSA 110
GR L+ + L+ G D TA G T +H A + + V ++L + G+N +
Sbjct: 202 GRELV-QILLAAGADPTAQ-DAQHGRTALHTAAMANNVELVRVIL----DAGVNANIRNV 255
Query: 111 RRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAME 154
P+H+A + C++LLL+ G+D ++D+EG+ H+A +
Sbjct: 256 HNTIPLHMALARGANSCVSLLLESGSDCNIQDDEGDNAFHIAAD 299
>Hs16159328 [R] KOG0504 FOG: Ankyrin repeat
Length = 683
Score = 57.4 bits (137), Expect = 3e-08
Identities = 34/109 (31%), Positives = 55/109 (50%), Gaps = 2/109 (1%)
Query: 62 LGHDATAMLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACR 121
L +DA ++ +G IH A G Q + LLL+ G S A + +P+H+A
Sbjct: 226 LQNDANPSIRDKEGYNSIHYAAAYGHRQCLELLLER-TNSGFEESDSGATK-SPLHLAAY 283
Query: 122 SNHSRCLALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCGGA 170
+ H + L +LLQ D+ + DE+G T L +A G +C+ L+ G +
Sbjct: 284 NGHHQALEVLLQSLVDLDIRDEKGRTALDLAAFKGHTECVEALINQGAS 332
Score = 53.5 bits (127), Expect = 4e-07
Identities = 37/138 (26%), Positives = 65/138 (46%), Gaps = 5/138 (3%)
Query: 30 DLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQ 89
D +I G++S+HYAA YG L++ + + + +HLA G Q
Sbjct: 229 DANPSIRDKEGYNSIHYAAAYGHRQCLELLLERTNSGFEESDSGATKSPLHLAAYNGHHQ 288
Query: 90 TVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDE-EGNTG 148
+ +LLQ ++ L++R R + +A H+ C+ L+ GA + ++D T
Sbjct: 289 ALEVLLQSLVD--LDIRDEKGR--TALDLAAFKGHTECVEALINQGASIFVKDNVTKRTP 344
Query: 149 LHVAMEYGAIQCLPILLQ 166
LH ++ G CL +LL+
Sbjct: 345 LHASVINGHTLCLRLLLE 362
Score = 53.5 bits (127), Expect = 4e-07
Identities = 45/162 (27%), Positives = 75/162 (45%), Gaps = 16/162 (9%)
Query: 12 AIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLK 71
A G + +L+R E DS S LH AA+ G + L+Q D ++
Sbjct: 246 AAAYGHRQCLELLLERTNSGFEESDSGATKSPLHLAAYNGHHQALEVLLQSLVDLD--IR 303
Query: 72 TYDGDTCIHLAITKGDEQTVHLLLQH----FLEEGLNLRSSSARRWAPIHIACRSNHSRC 127
G T + LA KG + V L+ F+++ + R+ P+H + + H+ C
Sbjct: 304 DEKGRTALDLAAFKGHTECVEALINQGASIFVKDNVTKRT-------PLHASVINGHTLC 356
Query: 128 LALLLQCGAD---VTLEDEEGNTGLHVAMEYGAIQCLPILLQ 166
L LLL+ + V ++D +G T L +A+ YG I + +LL+
Sbjct: 357 LRLLLEIADNPEAVDVKDAKGQTPLMLAVAYGHIDAVSLLLE 398
Score = 51.6 bits (122), Expect = 2e-06
Identities = 47/157 (29%), Positives = 69/157 (43%), Gaps = 15/157 (9%)
Query: 31 LLENIDST-------NGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAI 83
LL IDS+ G + LH AAF ++ C L+ L H A G T + +A
Sbjct: 530 LLGAIDSSIVSCRDDKGRTPLHAAAF-ADHVECLQLL-LRHSAPVNAVDNSGKTALMMAA 587
Query: 84 TKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDE 143
G V +L+ + L ++ P+H+AC H +C L+L D +L +E
Sbjct: 588 ENGQAGAVDILVNS-AQADLTVKDKDLN--TPLHLACSKGHEKCALLILDKIQDESLINE 644
Query: 144 EGN---TGLHVAMEYGAIQCLPILLQCGGATLADEQN 177
+ N T LHVA G + LL G LA ++N
Sbjct: 645 KNNALQTPLHVAARNGLKVVVEELLAKGACVLAVDEN 681
Score = 49.7 bits (117), Expect = 6e-06
Identities = 47/168 (27%), Positives = 73/168 (42%), Gaps = 16/168 (9%)
Query: 6 RIRLREAIVQGKLGVVRRILKRWPDLLENID--STNGWSSLHYAAFYGRYLICRHLIQLG 63
R L +++ G + R+L D E +D G + L A YG + L
Sbjct: 342 RTPLHASVINGHT-LCLRLLLEIADNPEAVDVKDAKGQTPLMLAVAYGHI----DAVSLL 396
Query: 64 HDATAMLKTYD--GDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACR 121
+ A + T D G T +H I G E+ V +LL E+ +++ +R P+H A
Sbjct: 397 LEKEANVDTVDILGCTALHRGIMTGHEECVQMLL----EQEVSILCKDSRGRTPLHYAAA 452
Query: 122 SNHSRCLALLLQCGA---DVTLEDEEGNTGLHVAMEYGAIQCLPILLQ 166
H+ L+ LLQ D +D +G T LH A G C+ +LL+
Sbjct: 453 RGHATWLSELLQMALSEEDCCFKDNQGYTPLHWACYNGNENCIEVLLE 500
>7291960_1 [R] KOG0504 FOG: Ankyrin repeat
Length = 507
Score = 57.4 bits (137), Expect = 3e-08
Identities = 43/114 (37%), Positives = 59/114 (51%), Gaps = 6/114 (5%)
Query: 40 GWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHLLLQHFL 99
G S+LH+AA + IC L+Q G + KT T +HLA G E+ V LLL L
Sbjct: 86 GMSALHFAAMNNQLEICEILLQGGINMDG--KTKVDRTPLHLACYYGHERIVSLLLA--L 141
Query: 100 EEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAM 153
+ +N R R P+H A H + LLL+C ADVTL + G T + +A+
Sbjct: 142 KCSVNSRDML--RMTPLHWAVEKKHKGIVRLLLKCQADVTLVSKFGKTPIGLAV 193
>Hs4506499 [R] KOG0502 Integral membrane ankyrin-repeat protein Kidins220
(protein kinase D substrate)
Length = 260
Score = 57.0 bits (136), Expect = 4e-08
Identities = 41/150 (27%), Positives = 74/150 (49%), Gaps = 7/150 (4%)
Query: 7 IRLREAIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDA 66
+ + + QG+L ++ L++ +L+ D G++ L +A+ +G R L++ G D
Sbjct: 92 LSIHQLAAQGELDQLKEHLRKGDNLVNKPDE-RGFTPLIWASAFGEIETVRFLLEWGADP 150
Query: 67 TAMLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSR 126
+ K + ++ + LA T G V LLL E +++ P+ A R NH +
Sbjct: 151 HILAK--ERESALSLASTGGYTDIVGLLL----ERDVDINIYDWNGGTPLLYAVRGNHVK 204
Query: 127 CLALLLQCGADVTLEDEEGNTGLHVAMEYG 156
C+ LL GAD+T E + G T + +A+ G
Sbjct: 205 CVEALLARGADLTTEADSGYTPMDLAVALG 234
>Hs20556512 [T] KOG0507 CASK-interacting adaptor protein (caskin) and related
proteins with ankyrin repeats and SAM domain
Length = 765
Score = 56.2 bits (134), Expect = 6e-08
Identities = 54/211 (25%), Positives = 80/211 (37%), Gaps = 54/211 (25%)
Query: 9 LREAIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATA 68
L A + G VV +L+ D L N+ + G LH AA+ G I R LI G T
Sbjct: 157 LHHAALNGHKDVVEVLLRN--DALTNVADSKGCYPLHLAAWKGDAQIVRLLIHQGPSHTR 214
Query: 69 M----------LKTY------------DGDTCIHLAITKGDEQTVHLLLQHFLEEGL--- 103
+ LK Y D +T +H A G + V +LL+ + +
Sbjct: 215 VNEQNALEIKELKKYGPFDPYINAKNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNN 274
Query: 104 --------------------------NLRSSSARRWAPIHIACRSNHSRCLALLLQCGAD 137
NL S + ++ P+H+A R+ H + +LL G D
Sbjct: 275 KFETPLDLAALYGRLEVVKMLLNAHPNLLSCNTKKHTPLHLAARNGHKAVVQVLLDAGMD 334
Query: 138 VTLEDEEGNTGLHVAMEYGAIQCLPILLQCG 168
+ E G + LH A +G + ILL G
Sbjct: 335 SNYQTEMG-SALHEAALFGKTDVVQILLAAG 364
>Hs18079216 [T] KOG0507 CASK-interacting adaptor protein (caskin) and related
proteins with ankyrin repeats and SAM domain
Length = 1431
Score = 56.2 bits (134), Expect = 6e-08
Identities = 49/164 (29%), Positives = 74/164 (44%), Gaps = 9/164 (5%)
Query: 9 LREAIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATA 68
L A QG+ ++ +LK + NI S G LH AA +G Y + L+Q H +
Sbjct: 86 LHYAAWQGRKEPMKLVLKAGSAV--NIPSDEGHIPLHLAAQHGHYDVSEMLLQ--HQSNP 141
Query: 69 MLKTYDGDTCIHLAITKGDEQTVHLLLQH----FLEEGLNLRSSSARRWAPIHIACRSNH 124
+ G T + LA G V LLL L E ++ +P+H+A ++ H
Sbjct: 142 CMVDNSGKTPLDLACEFGRVGVVQLLLSSNMCAALLEPRPGDATDPNGTSPLHLAAKNGH 201
Query: 125 SRCLALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCG 168
+ LLLQ G D+ + + G T LH A G + + +LL G
Sbjct: 202 IDIIRLLLQAGIDINRQTKSG-TALHEAALCGKTEVVRLLLDSG 244
Score = 50.1 bits (118), Expect = 5e-06
Identities = 35/132 (26%), Positives = 63/132 (47%), Gaps = 6/132 (4%)
Query: 34 NIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHL 93
N +G+S+LH+AA G + L++ A +K G +H A +G ++ + L
Sbjct: 43 NFQDPDGFSALHHAALNGNTELISLLLEA--QAAVDIKDNKGMRPLHYAAWQGRKEPMKL 100
Query: 94 LLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAM 153
+L+ G + S P+H+A + H +LLQ ++ + D G T L +A
Sbjct: 101 VLK----AGSAVNIPSDEGHIPLHLAAQHGHYDVSEMLLQHQSNPCMVDNSGKTPLDLAC 156
Query: 154 EYGAIQCLPILL 165
E+G + + +LL
Sbjct: 157 EFGRVGVVQLLL 168
>Hs17441942 [R] KOG0504 FOG: Ankyrin repeat
Length = 361
Score = 56.2 bits (134), Expect = 6e-08
Identities = 38/119 (31%), Positives = 59/119 (48%), Gaps = 6/119 (5%)
Query: 39 NGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHLLLQHF 98
+G S LH AA +G ++ L+ GH AT L+T +G +H A GD + LL
Sbjct: 120 SGVSPLHLAARFGHPVLVEWLLHEGHSAT--LETREGARPLHHAAVSGDLTCLKLLT--- 174
Query: 99 LEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQ-CGADVTLEDEEGNTGLHVAMEYG 156
G ++ + +P+++AC+ H L++ CGADV L +G + LH A G
Sbjct: 175 AAHGSSVNRRTRSGASPLYLACQEGHLHLAQFLVKDCGADVHLRALDGMSALHAAAARG 233
>CE20486 [OT] KOG0505 Myosin phosphatase regulatory subunit
Length = 1016
Score = 56.2 bits (134), Expect = 6e-08
Identities = 53/192 (27%), Positives = 82/192 (42%), Gaps = 34/192 (17%)
Query: 9 LREAIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATA 68
L ++++ K +VR + ++ D+ N GW+ LH AA G I R+L Q H A
Sbjct: 92 LHQSVIDSKPEMVRFLCEKGADV--NAQDNEGWTPLHAAACCGNVAIVRYLCQ--HGADL 147
Query: 69 MLKTYDGDTCIHLAITKGDEQTVHLL------------------LQHFLEEGLNLRSSSA 110
+ D + + LA+ DEQ L LQ L++ S
Sbjct: 148 SIVNSDKELALDLAV---DEQCRDYLDDDYKRQMIDLDACRDQELQTMLKDVNMWMSQGE 204
Query: 111 RRWAP--------IHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLP 162
R P +H+A +++ L LL++ G +V +D EG T LH A +
Sbjct: 205 YRDIPHHRTGGTAMHVAAGRGYTQLLELLIKAGGNVRAQDVEGWTPLHAAAHWAERDACK 264
Query: 163 ILLQCGGATLAD 174
ILL+ GA L+D
Sbjct: 265 ILLE-NGAELSD 275
>At5g40160 [R] KOG0504 FOG: Ankyrin repeat
Length = 315
Score = 56.2 bits (134), Expect = 6e-08
Identities = 37/125 (29%), Positives = 64/125 (50%), Gaps = 7/125 (5%)
Query: 32 LENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTV 91
++++D N ++LH A + + HL++ G A L+ DG IH A+ G QTV
Sbjct: 178 IDDVDKDNQ-TALHKAIIGKKEAVISHLLRKG--ANPHLQDRDGAAPIHYAVQVGALQTV 234
Query: 92 HLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHV 151
LL ++ +++ + W P+HIA +S + +LL GAD T ++G L +
Sbjct: 235 KLLFKY----NVDVNVADNEGWTPLHIAVQSRNRDITKILLTNGADKTRRTKDGKLALDL 290
Query: 152 AMEYG 156
A+ +G
Sbjct: 291 ALCFG 295
Score = 50.8 bits (120), Expect = 3e-06
Identities = 41/132 (31%), Positives = 59/132 (44%), Gaps = 6/132 (4%)
Query: 37 STNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHLLLQ 96
ST W L A + + +LI+ G D + K D T +H AI G ++ V +
Sbjct: 149 STKSWKPLQTLALSMQIQLMDNLIENGLDIDDVDK--DNQTALHKAII-GKKEAV---IS 202
Query: 97 HFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAMEYG 156
H L +G N APIH A + + + LL + DV + D EG T LH+A++
Sbjct: 203 HLLRKGANPHLQDRDGAAPIHYAVQVGALQTVKLLFKYNVDVNVADNEGWTPLHIAVQSR 262
Query: 157 AIQCLPILLQCG 168
ILL G
Sbjct: 263 NRDITKILLTNG 274
>7298524_2 [R] KOG0504 FOG: Ankyrin repeat
Length = 611
Score = 56.2 bits (134), Expect = 6e-08
Identities = 40/145 (27%), Positives = 71/145 (48%), Gaps = 5/145 (3%)
Query: 9 LREAIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATA 68
L +AI + VV +L P+L + + G++ LH+AA G + R ++ L
Sbjct: 129 LHDAIGKENTEVVE-LLCNAPNLDFTVKNNRGFNVLHHAALKGNVVAARRILLLSRQLVN 187
Query: 69 MLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCL 128
+ K DG +HLA G Q V L+ E L++R++ R+ P +A H+ +
Sbjct: 188 VRKD-DGFAALHLAALNGHAQVVETLVTEGQAE-LDIRNN--RQQTPFLLAVSQGHAGVI 243
Query: 129 ALLLQCGADVTLEDEEGNTGLHVAM 153
L++ DV +DE+G+ +H+ +
Sbjct: 244 ERLVRLSCDVNAKDEDGDNAMHLCV 268
Score = 54.3 bits (129), Expect = 2e-07
Identities = 42/139 (30%), Positives = 69/139 (49%), Gaps = 8/139 (5%)
Query: 15 QGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYD 74
QG L VR+ L P ++ + + G + + A+ G + +LI G + A+ K +
Sbjct: 3 QGHLDFVRQYLDVNPSQVDVM--SGGKACIQVASHQGYVDLVSYLISKGANVNAVDK--E 58
Query: 75 GDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQC 134
GD+ +H A T+ +LLQH E +N +SS + +HI C+ LLQ
Sbjct: 59 GDSALHYAAFGNQPATMRVLLQHGAE--VNFLNSS--HCSALHICAHKKTPHCVRELLQH 114
Query: 135 GADVTLEDEEGNTGLHVAM 153
A+V ++D G+T LH A+
Sbjct: 115 NANVNIQDSYGDTALHDAI 133
>SPAC2F7.10 [R] KOG0509 Ankyrin repeat and DHHC-type Zn-finger domain
containing proteins
Length = 642
Score = 55.8 bits (133), Expect = 8e-08
Identities = 47/171 (27%), Positives = 79/171 (45%), Gaps = 12/171 (7%)
Query: 12 AIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLK 71
A QG+L V+ ++ + N G ++LH+AA + IC+ L++ G D A+
Sbjct: 7 AASQGELDTVKNLISS-EKIDVNATDEGGATALHWAALNQQIPICKFLLEHGADVNAI-- 63
Query: 72 TYDGD---TCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCL 128
GD IH A +G +TVH L+QH G + + + +H+A + +
Sbjct: 64 --GGDLQAAPIHWAAKRGSVKTVHYLVQH----GADPLLKDKQGFNCLHLAVHAASPLLV 117
Query: 129 ALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCGGATLADEQNQM 179
LL V L D++ +T L A +G LL+ G LA ++++M
Sbjct: 118 VYLLHLDISVDLRDDQQHTPLMWASYHGNEPITNCLLRWGADVLATDEDKM 168
Score = 54.3 bits (129), Expect = 2e-07
Identities = 39/126 (30%), Positives = 63/126 (49%), Gaps = 6/126 (4%)
Query: 44 LHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGL 103
+H+AA G +L+Q H A +LK G C+HLA+ V LL L+ +
Sbjct: 72 IHWAAKRGSVKTVHYLVQ--HGADPLLKDKQGFNCLHLAVHAASPLLVVYLLH--LDISV 127
Query: 104 NLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPI 163
+LR ++ P+ A + LL+ GADV DE+ T LH ++ G ++C+ +
Sbjct: 128 DLRDD--QQHTPLMWASYHGNEPITNCLLRWGADVLATDEDKMTPLHWSIVGGNLKCMKL 185
Query: 164 LLQCGG 169
+L+ GG
Sbjct: 186 ILKEGG 191
>Hs4506217 [O] KOG4412 26S proteasome regulatory complex subunit PSMD10
Length = 226
Score = 55.8 bits (133), Expect = 8e-08
Identities = 42/144 (29%), Positives = 72/144 (49%), Gaps = 8/144 (5%)
Query: 9 LREAIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATA 68
L A G+ +V+ +L + + N + NG + LHYAA R+ I L++ G + A
Sbjct: 77 LHIAASAGRDEIVKALLGKGAQV--NAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDA 134
Query: 69 MLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCL 128
K + T +H A KG+ + +H+LL + + N++ + P+H+AC
Sbjct: 135 --KDHYEATAMHRAAAKGNLKMIHILL--YYKASTNIQDTEGN--TPLHLACDEERVEEA 188
Query: 129 ALLLQCGADVTLEDEEGNTGLHVA 152
LL+ GA + +E++E T L VA
Sbjct: 189 KLLVSQGASIYIENKEEKTPLQVA 212
Score = 55.1 bits (131), Expect = 1e-07
Identities = 45/175 (25%), Positives = 78/175 (43%), Gaps = 8/175 (4%)
Query: 4 EPRIRLREAIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLG 63
+ R L A G +V +L+ + + D+ GWS LH AA GR I + L+ G
Sbjct: 39 DSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDA--GWSPLHIAASAGRDEIVKALLGKG 96
Query: 64 HDATAMLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSN 123
A+ +G T +H A +K + +LL E G N + +H A
Sbjct: 97 AQVNAV--NQNGCTPLHYAASKNRHEIAVMLL----EGGANPDAKDHYEATAMHRAAAKG 150
Query: 124 HSRCLALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCGGATLADEQNQ 178
+ + + +LL A ++D EGNT LH+A + ++ +L+ G + + + +
Sbjct: 151 NLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIYIENKEE 205
>Hs18426879 [BK] KOG1082 Histone H3 (Lys9) methyltransferase SUV39H1/Clr4
required for transcriptional silencing
Length = 1176
Score = 55.8 bits (133), Expect = 8e-08
Identities = 37/111 (33%), Positives = 53/111 (47%), Gaps = 5/111 (4%)
Query: 55 ICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWA 114
+ R+++Q G K DG TC+H A G+ + V LLL +++ + + W
Sbjct: 699 VARYMVQRG--GCVYSKEEDGSTCLHHAAKIGNLEMVSLLLS---TGQVDVNAQDSGGWT 753
Query: 115 PIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILL 165
PI A H + +LL GADVTL D E N LH A G+ +LL
Sbjct: 754 PIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLL 804
Score = 49.7 bits (117), Expect = 6e-06
Identities = 33/121 (27%), Positives = 56/121 (46%), Gaps = 6/121 (4%)
Query: 34 NIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHL 93
N + GW+ + +AA + + R L+ G D T L + + C+H A G +
Sbjct: 745 NAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVT--LTDNEENICLHWASFTGSAAIAEV 802
Query: 94 LLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAM 153
LL +L + + P+HIA R ++ C+ L L GA+ L ++EG+T +
Sbjct: 803 LLN----ARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDLTP 858
Query: 154 E 154
E
Sbjct: 859 E 859
>Hs18375637 [BK] KOG1082 Histone H3 (Lys9) methyltransferase SUV39H1/Clr4
required for transcriptional silencing
Length = 1210
Score = 55.8 bits (133), Expect = 8e-08
Identities = 37/111 (33%), Positives = 53/111 (47%), Gaps = 5/111 (4%)
Query: 55 ICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWA 114
+ R+++Q G K DG TC+H A G+ + V LLL +++ + + W
Sbjct: 733 VARYMVQRG--GCVYSKEEDGSTCLHHAAKIGNLEMVSLLLS---TGQVDVNAQDSGGWT 787
Query: 115 PIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILL 165
PI A H + +LL GADVTL D E N LH A G+ +LL
Sbjct: 788 PIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLL 838
Score = 49.7 bits (117), Expect = 6e-06
Identities = 33/121 (27%), Positives = 56/121 (46%), Gaps = 6/121 (4%)
Query: 34 NIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHL 93
N + GW+ + +AA + + R L+ G D T L + + C+H A G +
Sbjct: 779 NAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVT--LTDNEENICLHWASFTGSAAIAEV 836
Query: 94 LLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAM 153
LL +L + + P+HIA R ++ C+ L L GA+ L ++EG+T +
Sbjct: 837 LLN----ARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDLTP 892
Query: 154 E 154
E
Sbjct: 893 E 893
>7296976 [M] KOG4177 Ankyrin
Length = 599
Score = 55.8 bits (133), Expect = 8e-08
Identities = 49/163 (30%), Positives = 76/163 (46%), Gaps = 8/163 (4%)
Query: 4 EPRIRLREAIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLG 63
E R L A +G L V +L + N S G ++LH AA G + + LI+
Sbjct: 433 EGRSALHLAAERGYLHVCDALLTNKAFI--NSKSRVGRTALHLAAMNGFTHLVKFLIK-D 489
Query: 64 HDATAMLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSN 123
H+A + T T +HLA G + LLL E G N+ ++ PIH+A ++N
Sbjct: 490 HNAVIDILTLRKQTPLHLAAASGQMEVCQLLL----ELGANIDATDDLGQKPIHVAAQNN 545
Query: 124 HSRCLALLLQCGAD-VTLEDEEGNTGLHVAMEYGAIQCLPILL 165
+S L LQ V ++GNT H+A G+++ + L+
Sbjct: 546 YSEVAKLFLQQHPSLVNATSKDGNTCAHIAAMQGSVKVIEELM 588
Score = 55.5 bits (132), Expect = 1e-07
Identities = 43/140 (30%), Positives = 67/140 (47%), Gaps = 6/140 (4%)
Query: 34 NIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHL 93
++ + +G S+H AA YG I L+Q G + T D T +H+A+ V
Sbjct: 136 HMPNKDGARSIHTAAAYGHTGIINTLLQKGEKVD--VTTNDNYTALHIAVESAKPAVVET 193
Query: 94 LLQHFLEEGLNLRSSSARRWAPIHIACR-SNHSRCLALLLQCGADVTLEDEEGNTGLHVA 152
LL + +++R R P+HIA R + RC +LL+ GA L ++ T +HVA
Sbjct: 194 LLGFGAD--VHVRGGKLRE-TPLHIAARVKDGDRCALMLLKSGASPNLTTDDCLTPVHVA 250
Query: 153 MEYGAIQCLPILLQCGGATL 172
+G + L LL+ G L
Sbjct: 251 ARHGNLATLMQLLEDEGDPL 270
Score = 52.8 bits (125), Expect = 7e-07
Identities = 38/133 (28%), Positives = 61/133 (45%), Gaps = 5/133 (3%)
Query: 34 NIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHL 93
++ T G S+LH AA G +C L L + A K+ G T +HLA G V
Sbjct: 428 DVFDTEGRSALHLAAERGYLHVCDAL--LTNKAFINSKSRVGRTALHLAAMNGFTHLVKF 485
Query: 94 LLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAM 153
L++ + + + R+ P+H+A S LLL+ GA++ D+ G +HVA
Sbjct: 486 LIK---DHNAVIDILTLRKQTPLHLAAASGQMEVCQLLLELGANIDATDDLGQKPIHVAA 542
Query: 154 EYGAIQCLPILLQ 166
+ + + LQ
Sbjct: 543 QNNYSEVAKLFLQ 555
Score = 50.4 bits (119), Expect = 4e-06
Identities = 35/115 (30%), Positives = 53/115 (45%), Gaps = 7/115 (6%)
Query: 55 ICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHLLLQHF----LEEGLNLRSSSA 110
I R L++ G D T KT +T H G+ + ++ H +++ +N +SS
Sbjct: 343 IVRMLLENGADVTLQTKTAL-ETAFHYCAVAGNNDVLMEMISHMNPTDIQKAMNRQSSVG 401
Query: 111 RRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILL 165
W P+ IAC H + LL A V + D EG + LH+A E G + LL
Sbjct: 402 --WTPLLIACHRGHMELVNNLLANHARVDVFDTEGRSALHLAAERGYLHVCDALL 454
>7298294 [R] KOG0504 FOG: Ankyrin repeat
Length = 500
Score = 55.5 bits (132), Expect = 1e-07
Identities = 35/106 (33%), Positives = 55/106 (51%), Gaps = 3/106 (2%)
Query: 74 DGDTCIHLAITKGDEQTVHLLLQHFLEEGL-NLRSSSARRWAPIHIACRSNHSRCLALLL 132
DGDT +HLA G V L++ L N+++ A+ P+H+A + + +LL
Sbjct: 229 DGDTPLHLACISGSVDVVAALIRMAPHPCLLNIQNDVAQ--TPLHLAALTAQPNIMRILL 286
Query: 133 QCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCGGATLADEQNQ 178
GA+ T+ D GNT LH++ G QC+ L + GAT E ++
Sbjct: 287 LAGAEPTVRDRHGNTALHLSCIAGEKQCVRALTEKFGATEIHEAHR 332
Score = 50.8 bits (120), Expect = 3e-06
Identities = 51/192 (26%), Positives = 86/192 (44%), Gaps = 15/192 (7%)
Query: 9 LREAIVQGKLGVVRRILKRWPD-LLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDAT 67
L A + G + VV +++ P L NI + + LH AA + I R L+ G + T
Sbjct: 234 LHLACISGSVDVVAALIRMAPHPCLLNIQNDVAQTPLHLAALTAQPNIMRILLLAGAEPT 293
Query: 68 AMLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRC 127
++ G+T +HL+ G++Q V L + F G + R++ RSN
Sbjct: 294 --VRDRHGNTALHLSCIAGEKQCVRALTEKF---GATEIHEAHRQYGH-----RSNDKAV 343
Query: 128 LALLLQC-GADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCGGATLADEQNQMGIVARQV 186
+L C AD+ + + +G +H+A E G I L IL+ GA + + + G +
Sbjct: 344 SSLSYACLPADLEIRNYDGERCVHLAAEAGHIDILRILVS-HGADINAREGKSGRTPLHI 402
Query: 187 G--NCDETIKKF 196
C+E + F
Sbjct: 403 AIEGCNEDLANF 414
>7294194 [OT] KOG0505 Myosin phosphatase regulatory subunit
Length = 1023
Score = 55.5 bits (132), Expect = 1e-07
Identities = 44/185 (23%), Positives = 78/185 (41%), Gaps = 31/185 (16%)
Query: 9 LREAIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATA 68
L +A + L +V +++R D+ N GW+ LH A G I R+L++ G D A
Sbjct: 83 LHQACIDDNLDMVEFLVERGADI--NRQDNEGWTPLHATASCGFVSIARYLVENGADVAA 140
Query: 69 MLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSS----------SARRW----- 113
+ DGD + LAI + + + E +N+ + A++W
Sbjct: 141 V--NSDGDLALDLAIDVQHMAMIDYMEKMVQELNINVDEARKAEELAMLNDAKKWLRSDA 198
Query: 114 ------------APIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCL 161
+H+A +++ L LLL +V +D +G T LH A +G +
Sbjct: 199 AEVDRPHPKTGATALHVAAAKGYTKVLGLLLAGRGNVDRQDNDGWTPLHAASHWGQRETA 258
Query: 162 PILLQ 166
+L++
Sbjct: 259 EMLVE 263
>Hs11968152_1 [R] KOG0504 FOG: Ankyrin repeat
Length = 654
Score = 55.1 bits (131), Expect = 1e-07
Identities = 48/149 (32%), Positives = 67/149 (44%), Gaps = 9/149 (6%)
Query: 39 NGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCI-HLAITKGDEQTVHLLLQH 97
+G ++LH AA L L+ LG + K G T + H A+ GD + LLL +
Sbjct: 246 DGMTALHKAACARHCLALTALLDLG--GSPNYKDRRGLTPLFHTAMVGGDPRCCELLLFN 303
Query: 98 FLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAMEYGA 157
+ G+ + W IH AC+ HS+ L LL GA+ ++ GNT LH+ Y
Sbjct: 304 RAQLGI----ADENGWQEIHQACQRGHSQHLEHLLFYGAEPGAQNASGNTALHICALYNK 359
Query: 158 IQCLPILLQCGGATLADEQNQMGIVARQV 186
C ILL G D +N G QV
Sbjct: 360 ETCARILLYRGAD--KDVKNNNGQTPFQV 386
>CE04223 [R] KOG0504 FOG: Ankyrin repeat
Length = 280
Score = 54.7 bits (130), Expect = 2e-07
Identities = 47/160 (29%), Positives = 71/160 (44%), Gaps = 19/160 (11%)
Query: 11 EAIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAML 70
E +++ L + +R DL +N + T LH A G ++ ++ I + +
Sbjct: 54 EKLLKNLLSIPKR------DLCDNEEFT----PLHNAVKMGNTVMAKNFID---SKSVWI 100
Query: 71 KTYD--GDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCL 128
D G T +HL+IT GD + LLL+ G N+ S + HIAC+
Sbjct: 101 DEPDCRGQTALHLSITYGDTEMTSLLLKG----GANVDSVDYDGISACHIACKDGMIDHF 156
Query: 129 ALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCG 168
LL+ AD+ L D G T +A EYG + L L CG
Sbjct: 157 NLLIYYHADICLVDRSGRTPFDLACEYGQEKMLERLFSCG 196
>At5g02620 [R] KOG0504 FOG: Ankyrin repeat
Length = 517
Score = 54.7 bits (130), Expect = 2e-07
Identities = 45/163 (27%), Positives = 80/163 (48%), Gaps = 10/163 (6%)
Query: 9 LREAIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATA 68
L A QG +V +L + DL I +NG ++LH AA G +I + LI+
Sbjct: 122 LHTAASQGHGEIVCFLLDKGVDLAA-IARSNGKTALHSAARNGHTVIVKKLIE---KKAG 177
Query: 69 MLKTYD--GDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSR 126
M+ D G T +H+A+ + + V +L++ +G + S+ + P+HIA R N +
Sbjct: 178 MVTRVDKKGQTALHMAVKGQNTEIVDVLME---ADGSLINSADNKGNTPLHIAVRKNRAE 234
Query: 127 CLALLLQ-CGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCG 168
+ +L+ C ++ G T L +A + G + +P+L + G
Sbjct: 235 IVQTVLKYCEVSRVAVNKSGETALDIAEKTGLHEIVPLLQKIG 277
Score = 51.2 bits (121), Expect = 2e-06
Identities = 40/166 (24%), Positives = 79/166 (47%), Gaps = 9/166 (5%)
Query: 16 GKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDG 75
G +V+ ++K +L + NG+ + H AA G + LI+ + + T+D
Sbjct: 60 GYTDMVKILMKHSDSVLAGTKAKNGFDAFHIAAKNGNLQVLDVLIEANPELSF---TFDS 116
Query: 76 D--TCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQ 133
T +H A ++G + V LL ++ RS+ +H A R+ H+ + L++
Sbjct: 117 SKTTALHTAASQGHGEIVCFLLDKGVDLAAIARSNGK---TALHSAARNGHTVIVKKLIE 173
Query: 134 CGAD-VTLEDEEGNTGLHVAMEYGAIQCLPILLQCGGATLADEQNQ 178
A VT D++G T LH+A++ + + +L++ G+ + N+
Sbjct: 174 KKAGMVTRVDKKGQTALHMAVKGQNTEIVDVLMEADGSLINSADNK 219
>At1g07710 [R] KOG0504 FOG: Ankyrin repeat
Length = 543
Score = 54.7 bits (130), Expect = 2e-07
Identities = 41/155 (26%), Positives = 76/155 (48%), Gaps = 6/155 (3%)
Query: 12 AIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLK 71
A QG L V++ + + +L +D +N ++LH AA G + L++LG + K
Sbjct: 108 AAKQGDLDVLKVLAEAHSELAMTVDLSNT-TALHTAATQGHTEVVNFLLELGSSLAGIAK 166
Query: 72 TYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALL 131
+ +G T +H A G + + LL E + +R + A +H+A + + + L
Sbjct: 167 S-NGKTALHSASRNGHVKVIKALLAS--EPAIAIRMDKKGQTA-LHMAVKGTNVEVVEEL 222
Query: 132 LQCG-ADVTLEDEEGNTGLHVAMEYGAIQCLPILL 165
++ + + + D +GNT LH+A G Q + +LL
Sbjct: 223 IKADRSSINIADTKGNTALHIAARKGRSQIVKLLL 257
Score = 52.4 bits (124), Expect = 9e-07
Identities = 50/217 (23%), Positives = 97/217 (44%), Gaps = 16/217 (7%)
Query: 16 GKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDG 75
G + +V+ ++ + L I + NG+ + H AA G + + L + H AM
Sbjct: 77 GDVEIVKEMINCYDLALVEIKARNGFDAFHIAAKQGDLDVLKVLAE-AHSELAMTVDLSN 135
Query: 76 DTCIHLAITKGDEQTVHLLLQHFLEEGLNLRS-SSARRWAPIHIACRSNHSRCLALLLQC 134
T +H A T+G + V+ L LE G +L + + +H A R+ H + + LL
Sbjct: 136 TTALHTAATQGHTEVVNFL----LELGSSLAGIAKSNGKTALHSASRNGHVKVIKALLAS 191
Query: 135 GADVTLE-DEEGNTGLHVAMEYGAIQCLPILLQC--GGATLADEQNQMGI-VARQVGNCD 190
+ + D++G T LH+A++ ++ + L++ +AD + + +A + G
Sbjct: 192 EPAIAIRMDKKGQTALHMAVKGTNVEVVEELIKADRSSINIADTKGNTALHIAARKGR-S 250
Query: 191 ETIK-----KFDQFAAEIRKGVSSGSSTVPIGTPDIA 222
+ +K A R G ++ + IG P++A
Sbjct: 251 QIVKLLLANNMTDTKAVNRSGETALDTAEKIGNPEVA 287
>7297920 [R] KOG0509 Ankyrin repeat and DHHC-type Zn-finger domain
containing proteins
Length = 585
Score = 54.7 bits (130), Expect = 2e-07
Identities = 40/158 (25%), Positives = 68/158 (42%), Gaps = 4/158 (2%)
Query: 11 EAIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAML 70
+ I G++ V ++ ++ + +G++ H+ A G + R+LI+
Sbjct: 92 DIIKNGEVSEVENLVDKFGMECLSARDRHGYTPAHWIALNGNVQLMRYLIERTAPIDLPC 151
Query: 71 KTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLAL 130
G IH A KG V +LLQ G+ + ++ + P+H+AC + A
Sbjct: 152 LGTQGPRPIHWACRKGHASVVQVLLQ----AGVAVNAADFKGLTPLHLACMYGRTATAAY 207
Query: 131 LLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCG 168
LL GA L D G+T LH A G + +L+ G
Sbjct: 208 LLGMGALNNLTDINGDTALHWAAYKGHADLMRLLMYSG 245
>Hs4557349_2 [R] KOG0504 FOG: Ankyrin repeat
Length = 162
Score = 54.7 bits (130), Expect = 2e-07
Identities = 32/103 (31%), Positives = 52/103 (50%), Gaps = 4/103 (3%)
Query: 68 AMLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRC 127
A+ + + G+T +H+A KGD +V LLQ+ G + W P+H AC H +
Sbjct: 12 AVKRNHRGETLLHIASIKGDIPSVEYLLQN----GSDPNVKDHAGWTPLHEACNHGHLKV 67
Query: 128 LALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCGGA 170
+ LLLQ A V + ++ LH A + G + + +LL G +
Sbjct: 68 VELLLQHKALVNTTGYQNDSPLHDAAKNGHVDIVKLLLSYGAS 110
>Hs22051302 [R] KOG0514 Ankyrin repeat protein
Length = 389
Score = 54.3 bits (129), Expect = 2e-07
Identities = 51/199 (25%), Positives = 87/199 (43%), Gaps = 17/199 (8%)
Query: 29 PDLLE---NIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAIT- 84
P+LL N+ NG ++LHY+ +G I L+ G + A+T
Sbjct: 177 PELLAHVVNLADGNGNTALHYSVSHGNLAIASLLLDTGACEVNRQNRAGYSALMLAALTS 236
Query: 85 -KGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDE 143
+ +E+ + ++ + F +N ++S + A + +A +A LL CGADV +D
Sbjct: 237 VRQEEEDMAVVQRLFCMGDVNAKASQTGQTA-LMLAISHGRQDMVATLLACGADVNAQDA 295
Query: 144 EGNTGLHVAMEYGAIQCLPILLQ---CGGATLADEQNQMGIVARQVGNCDETIKKFDQFA 200
+G T L A EYG + + +LL C A L +E +A + + D+ A
Sbjct: 296 DGATALMCASEYGRLDTVRLLLTQPGCDPAILDNEGTSALAIALEA--------EQDEVA 347
Query: 201 AEIRKGVSSGSSTVPIGTP 219
A + +SSG +P
Sbjct: 348 ALLHAHLSSGQPDTQSESP 366
>Hs4505319 [OT] KOG0505 Myosin phosphatase regulatory subunit
Length = 982
Score = 53.9 bits (128), Expect = 3e-07
Identities = 45/184 (24%), Positives = 79/184 (42%), Gaps = 33/184 (17%)
Query: 9 LREAIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATA 68
L +A + L +V+ +++ ++ N GW+ LH AA G I + I H A+
Sbjct: 95 LHQACIDENLDMVKFLVENRANV--NQQDNEGWTPLHAAASCGYLNIAEYFIN--HGASV 150
Query: 69 MLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSS----------SARRW----- 113
+ +G+ LA + LLL+ ++G++L S AR+W
Sbjct: 151 GIVNSEGEVPSDLA---EEPAMKDLLLEQVKKQGIDLEQSRKEEEQQMLQDARQWLNSGK 207
Query: 114 -----------APIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLP 162
+H+A +S L LL+Q G ++ ++D +G T LH A +G +
Sbjct: 208 IEDVRQARSGATALHVAAAKGYSEVLRLLIQAGYELNVQDYDGWTPLHAAAHWGVKEACS 267
Query: 163 ILLQ 166
IL +
Sbjct: 268 ILAE 271
>Hs22055239 [R] KOG0504 FOG: Ankyrin repeat
Length = 324
Score = 53.9 bits (128), Expect = 3e-07
Identities = 39/133 (29%), Positives = 60/133 (44%), Gaps = 3/133 (2%)
Query: 36 DSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHLLL 95
DS + WS + AA YG L R+LI G ++ D + +H A +G V +LL
Sbjct: 32 DSVSDWSPMPEAAIYGHQLSLRNLISHGWLVNIIMA--DHVSPLHEACLRGHPSRVKILL 89
Query: 96 QHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAMEY 155
+H + G +++ S +P+H A R H C+ L T L++A E
Sbjct: 90 KHGAQHGASVQPESDLA-SPVHEAARRGHVECVDSLTAYRGKNDHNISHVGTSLYLACEN 148
Query: 156 GAIQCLPILLQCG 168
I C+ LL+ G
Sbjct: 149 QQIACVKKLLESG 161
>Hs21314722 [BK] KOG1082 Histone H3 (Lys9) methyltransferase SUV39H1/Clr4
required for transcriptional silencing
Length = 1267
Score = 53.9 bits (128), Expect = 3e-07
Identities = 51/182 (28%), Positives = 72/182 (39%), Gaps = 34/182 (18%)
Query: 15 QGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHD--------- 65
QG+L V +L D ++ N S LH AA G IC L+Q G +
Sbjct: 717 QGELQKVLLMLVDGIDPNFKMEHQNKRSPLHAAAEAGHVDICHMLVQAGANIDTCSEDQR 776
Query: 66 --------------------ATAML--KTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGL 103
A A++ K +G TC+HLA KG + V LL + +
Sbjct: 777 TPLMEAAENNHLEAVKYLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLLSN---GQM 833
Query: 104 NLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPI 163
++ W P+ A H + LLL G+D+ + D E N LH A G + I
Sbjct: 834 DVNCQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEENICLHWAAFSGCVDIAEI 893
Query: 164 LL 165
LL
Sbjct: 894 LL 895
Score = 52.0 bits (123), Expect = 1e-06
Identities = 34/120 (28%), Positives = 55/120 (45%), Gaps = 8/120 (6%)
Query: 34 NIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHL 93
N GW+ + +A Y + + L+ G D ++ + + C+H A G +
Sbjct: 836 NCQDDGGWTPMIWATEYKHVDLVKLLLSKGSDIN--IRDNEENICLHWAAFSGCVDIAEI 893
Query: 94 LLQHFLE-EGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVA 152
LL + +N+ S P+HIA R N C+ L L +DVTL+++EG T L A
Sbjct: 894 LLAAKCDLHAVNIHGDS-----PLHIAARENRYDCVVLFLSRDSDVTLKNKEGETPLQCA 948
>Hs18640738 [R] KOG0504 FOG: Ankyrin repeat
Length = 475
Score = 53.9 bits (128), Expect = 3e-07
Identities = 44/167 (26%), Positives = 72/167 (42%), Gaps = 4/167 (2%)
Query: 2 IPEPRIRLREAIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQ 61
I E + + ++A+ G + +V+ +L + N GW+ L YAA + R L+
Sbjct: 43 IEEKKEKFKKAMTIGDVSLVQELLDSGISVDSNFQY--GWTPLMYAASVANAELVRVLLD 100
Query: 62 LGHDATAMLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACR 121
G A A + I G E+ + ++ L + + R PI A R
Sbjct: 101 RG--ANASFEKDKQSILITACSAHGSEEQILKCVELLLSRNADPNVACRRLMTPIMYAAR 158
Query: 122 SNHSRCLALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCG 168
H++ +ALL+ GA+V +DE G T L A G + LL+ G
Sbjct: 159 DGHTQVVALLVAHGAEVNTQDENGYTALTWAARQGHKNIVLKLLELG 205
>Hs14195601 [OT] KOG0505 Myosin phosphatase regulatory subunit
Length = 998
Score = 53.9 bits (128), Expect = 3e-07
Identities = 45/184 (24%), Positives = 79/184 (42%), Gaps = 33/184 (17%)
Query: 9 LREAIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATA 68
L +A + L +V+ +++ ++ N GW+ LH AA G I + I H A+
Sbjct: 95 LHQACIDENLDMVKFLVENRANV--NQQDNEGWTPLHAAASCGYLNIAEYFIN--HGASV 150
Query: 69 MLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSS----------SARRW----- 113
+ +G+ LA + LLL+ ++G++L S AR+W
Sbjct: 151 GIVNSEGEVPSDLA---EEPAMKDLLLEQVKKQGIDLEQSRKEEEQQMLQDARQWLNSGK 207
Query: 114 -----------APIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLP 162
+H+A +S L LL+Q G ++ ++D +G T LH A +G +
Sbjct: 208 IEDVRQARSGATALHVAAAKGYSEVLRLLIQAGYELNVQDYDGWTPLHAAAHWGVKEACS 267
Query: 163 ILLQ 166
IL +
Sbjct: 268 ILAE 271
>7298193 [K] KOG0512 Fetal globin-inducing factor (contains ankyrin repeats)
Length = 215
Score = 53.9 bits (128), Expect = 3e-07
Identities = 34/95 (35%), Positives = 47/95 (48%), Gaps = 5/95 (5%)
Query: 57 RHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPI 116
R +++L D T K DG T +H A LLLQ+ N + + W P+
Sbjct: 65 REILKLDAD-TVNAKDNDGYTPLHRAAYNNFVDMAKLLLQYHA----NPNARTELGWTPL 119
Query: 117 HIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHV 151
H AC+ N++ C LLLQ GADV E + T LH+
Sbjct: 120 HSACKWNNADCAHLLLQFGADVNAESDGKQTPLHI 154
>Hs22062923 [R] KOG0504 FOG: Ankyrin repeat
Length = 794
Score = 53.5 bits (127), Expect = 4e-07
Identities = 37/142 (26%), Positives = 67/142 (47%), Gaps = 5/142 (3%)
Query: 24 ILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAI 83
ILKR E +D+ G + LH A LI + + + ++ T +HLA+
Sbjct: 481 ILKRESGAAEQVDN-KGRNFLHVAVQNSDIESVLFLISVHANVNSRVQDASKLTPLHLAV 539
Query: 84 TKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDE 143
G E +++++ L G + + R +H+A + + ++LL+ G D DE
Sbjct: 540 QAGSE----IIVRNLLLAGAKVNELTKHRQTALHLAAQQDLPTICSVLLENGVDFAAVDE 595
Query: 144 EGNTGLHVAMEYGAIQCLPILL 165
GN LH+A+ +G + + +LL
Sbjct: 596 NGNNALHLAVMHGRLNNIRVLL 617
>Hs14149716 [OT] KOG0505 Myosin phosphatase regulatory subunit
Length = 782
Score = 53.5 bits (127), Expect = 4e-07
Identities = 50/187 (26%), Positives = 75/187 (39%), Gaps = 33/187 (17%)
Query: 9 LREAIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATA 68
L +A + L VVR ++++ + N GW+ LH AA G I R+L L H A
Sbjct: 105 LHQACIDENLEVVRFLVEQGATV--NQADNEGWTPLHVAASCGYLDIARYL--LSHGANI 160
Query: 69 MLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSS----------ARRW----- 113
DGD + LA + E LL G+++ ++ R W
Sbjct: 161 AAVNSDGDLPLDLAESDAMEG---LLKAEIARRGVDVEAAKRAEEELLLHDTRCWLNGGA 217
Query: 114 -----------APIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLP 162
+ +H+A + + LLLQ G D L D +G T LH A +G
Sbjct: 218 MPEARHPRTGASALHVAAAKGYIEVMRLLLQAGYDPELRDGDGWTPLHAAAHWGVEDACR 277
Query: 163 ILLQCGG 169
+L + GG
Sbjct: 278 LLAEHGG 284
>Hs13375989 [R] KOG0504 FOG: Ankyrin repeat
Length = 278
Score = 53.5 bits (127), Expect = 4e-07
Identities = 52/194 (26%), Positives = 81/194 (40%), Gaps = 9/194 (4%)
Query: 44 LHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGL 103
LH A+ G+ + L+ G A + DG T + A G + V L L + +
Sbjct: 56 LHAASLQGQARCVQLLLAAGAQVDA--RNIDGSTPLCDACASGSIECVKLSLSYGAKVNP 113
Query: 104 NLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPI 163
L ++S P+H AC S S C+ LL+ GA++ D T LHVA + C+ +
Sbjct: 114 PLYTAS-----PLHEACMSGSSECVRLLIDVGANLEAHDCHFGTPLHVACAREHLDCVKV 168
Query: 164 LLQCGGATLADEQNQMGI-VARQVGNCDETIKKFDQFAAEIRKGVSSGSSTVPIGTPDIA 222
LL G A + ++ + A +V N D I+ +F I + G A
Sbjct: 169 LLNAGANVNAAKLHETALHHAAKVKNVD-LIEMLIEFGGNIYARDNRGKKPSDYTWSSSA 227
Query: 223 ASKTFLGGNNGPLS 236
+K F PL+
Sbjct: 228 PAKCFEYYEKTPLT 241
>Hs12746412 [R] KOG0502 Integral membrane ankyrin-repeat protein Kidins220
(protein kinase D substrate)
Length = 313
Score = 53.5 bits (127), Expect = 4e-07
Identities = 37/128 (28%), Positives = 65/128 (49%), Gaps = 8/128 (6%)
Query: 34 NIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHL 93
N G++ L +AA +G+ + L+Q G D + K ++ + LA +KG V +
Sbjct: 176 NHTDEEGFTPLMWAAAHGQIAVVEFLLQNGADPQLLGK--GRESALSLACSKGYTDIVKM 233
Query: 94 LLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEG--NTGLHV 151
LL + G+++ P+ A NH +C+ +LL+ GAD T+E + G + L V
Sbjct: 234 LL----DCGVDVNEYDWNGGTPLLYAVHGNHVKCVKMLLESGADPTIETDSGYNSMDLAV 289
Query: 152 AMEYGAIQ 159
A+ Y ++Q
Sbjct: 290 ALGYRSVQ 297
>CE27723 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 850
Score = 53.5 bits (127), Expect = 4e-07
Identities = 49/181 (27%), Positives = 81/181 (44%), Gaps = 9/181 (4%)
Query: 12 AIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQL--GHDATAM 69
A +G + + +L+ D L D N +LHYAA G +I LI+ G +
Sbjct: 223 AAAKGLTSITKLLLEAKADPLLADDEGN--QALHYAAKSGSLVILNMLIKQVRGTNDRIC 280
Query: 70 LKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLA 129
+ GDT +HL+ G V +L +N+ + + P+H AC S L
Sbjct: 281 ARNLYGDTALHLSCYSGRLDIVKSILDSSPTNIVNMENVFSE--TPLHAACTGGKSIELV 338
Query: 130 --LLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCGG-ATLADEQNQMGIVARQV 186
L+ G D + ++G+T LH A +G ++ + LL+ G +LA + G + +Q
Sbjct: 339 SFLMKYPGVDPNYQGQDGHTALHSACYHGHLRIVQYLLENGADQSLASRAFEGGALRQQA 398
Query: 187 G 187
G
Sbjct: 399 G 399
Score = 50.1 bits (118), Expect = 5e-06
Identities = 44/164 (26%), Positives = 65/164 (38%), Gaps = 40/164 (24%)
Query: 37 STNGWSSLHYAAFYG-----RYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTV 91
S NG++ LH A + G + LI L+ L +L +HLA GD + +
Sbjct: 113 SANGFTPLHIAIYRGDVAILKALIATKLVDLDQSGRHLL------PALHLAAMIGDSEML 166
Query: 92 HLLLQ-----------HF------------------LEEGLNLRSSSARRWAPIHIACRS 122
+LL HF + NL A PIH+A
Sbjct: 167 TILLNSGANIHVTDFVHFTALHCATYFGQENAVRTLISASANLNLGGAVNDRPIHLAAAK 226
Query: 123 NHSRCLALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQ 166
+ LLL+ AD L D+EGN LH A + G++ L +L++
Sbjct: 227 GLTSITKLLLEAKADPLLADDEGNQALHYAAKSGSLVILNMLIK 270
>7304095 [T] KOG0521 Putative GTPase activating proteins (GAPs)
Length = 1019
Score = 53.5 bits (127), Expect = 4e-07
Identities = 35/115 (30%), Positives = 59/115 (50%), Gaps = 11/115 (9%)
Query: 63 GHDATAMLKTYD-GDTCIHLAITKGDEQTVHL---LLQHFLEEGLNLRSSSAR------R 112
G D T L + D G+T +HLA+ + T+H+ L+Q+ +GLN ++ A +
Sbjct: 554 GADLTCCLPSSDAGETALHLAVLREMGSTLHIVDFLIQNMPPKGLNKATNPAGLLDVTGK 613
Query: 113 WAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQC 167
+H+ + C+ LLL+ GAD L++ + T L +A E G C L++C
Sbjct: 614 NTALHLCALHDRRECMKLLLRSGADYELKNSQNKTALDIAKEMGHNSCRE-LIEC 667
>Hs4505317 [OT] KOG0505 Myosin phosphatase regulatory subunit
Length = 1030
Score = 53.1 bits (126), Expect = 5e-07
Identities = 53/211 (25%), Positives = 94/211 (44%), Gaps = 41/211 (19%)
Query: 9 LREAIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATA 68
L +A + + +V+ +++ ++ N GW LH AA G I LI G A
Sbjct: 77 LHQACIDDNVDMVKFLVENGANI--NQPDNEGWIPLHAAASCGYLDIAEFLIGQGAHVGA 134
Query: 69 MLKTYDGDTCIHLAITKGDEQTVHLLLQHFLE-EGLNLRSS----------SARRW---- 113
+ +GDT + +A +E+ + LLQ+ + +G+++ ++ AR+W
Sbjct: 135 V--NSEGDTPLDIA----EEEAMEELLQNEVNRQGVDIEAARKEEERIMLRDARQWLNSG 188
Query: 114 ------------APIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCL 161
+H+A ++ L LL+Q G DV ++D +G T LH A +G +
Sbjct: 189 HINDVRHAKSGGTALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAAAHWGKEEAC 248
Query: 162 PILLQCGGATLADEQ--NQMGIVARQVGNCD 190
IL+ L D + N++G A V + D
Sbjct: 249 RILVD----NLCDMEMVNKVGQTAFDVADED 275
>Hs21450703 [R] KOG0504 FOG: Ankyrin repeat
Length = 258
Score = 53.1 bits (126), Expect = 5e-07
Identities = 44/125 (35%), Positives = 57/125 (45%), Gaps = 7/125 (5%)
Query: 44 LHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGL 103
L AA YLI ++L G D A K + T +H A KG Q V+ LL G
Sbjct: 116 LKAAAENQEYLIDKYLTD-GGDPNAHDKLHR--TALHWACLKGHSQLVNKLLV----AGA 168
Query: 104 NLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPI 163
+ + P+ ACR H L LL GA V D+ G+T LHVA+ CL
Sbjct: 169 TVDARDLLDRTPVFWACRGGHLVILKQLLNQGARVNARDKIGSTPLHVAVRTRHPDCLEH 228
Query: 164 LLQCG 168
L++CG
Sbjct: 229 LIECG 233
>Hs22056002 [Z] KOG0676 Actin and related proteins
Length = 1149
Score = 52.8 bits (125), Expect = 7e-07
Identities = 42/144 (29%), Positives = 72/144 (49%), Gaps = 7/144 (4%)
Query: 44 LHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGL 103
LH AA++G+ + + LI + D + T +HLA G+ + V LLL + L
Sbjct: 447 LHRAAWWGK-VPRKDLIVMLRDTDMNKRDKQKRTALHLASANGNSEVVQLLLDRRCQ--L 503
Query: 104 NLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPI 163
N+ + R + C+ + C+ +LL+ GAD ++DE GNT LH A+ Y + +
Sbjct: 504 NVLDNKKRTALIKAVQCQEDE--CVLMLLEHGADGNIQDEYGNTALHYAI-YNEDKLMAK 560
Query: 164 LLQCGGATLADEQNQMGIVARQVG 187
L GA + + +N+ G+ +G
Sbjct: 561 ALLLYGADI-ESKNKCGLTPLLLG 583
>Hs22048285 [Z] KOG0676 Actin and related proteins
Length = 1107
Score = 52.4 bits (124), Expect = 9e-07
Identities = 43/144 (29%), Positives = 69/144 (47%), Gaps = 7/144 (4%)
Query: 44 LHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGL 103
LH AA++G+ + + LI + D K T +HLA G+ + V LLL + L
Sbjct: 342 LHRAAWWGK-VPRKDLIVMLKDTDMNKKDKQKRTALHLASANGNSEVVKLLLDRRCQ--L 398
Query: 104 NLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPI 163
N+ + R + CR + C +LL+ G D + DE GNT LH A+ Y + +
Sbjct: 399 NILDNKKRTALTKAVQCREDE--CALMLLEHGTDPNIPDEYGNTALHYAI-YNEDKLMAK 455
Query: 164 LLQCGGATLADEQNQMGIVARQVG 187
L GA + + +N+ G+ +G
Sbjct: 456 ALLLYGADI-ESKNKHGLTPLLLG 478
>Hs19924156 [R] KOG0502 Integral membrane ankyrin-repeat protein Kidins220
(protein kinase D substrate)
Length = 237
Score = 52.4 bits (124), Expect = 9e-07
Identities = 38/127 (29%), Positives = 61/127 (47%), Gaps = 6/127 (4%)
Query: 30 DLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQ 89
D L N G++ L +A+ +G R L++ G D + K + ++ + LA T G
Sbjct: 91 DNLVNKPDERGFTPLIWASAFGEIETVRFLLEWGADPHILAK--ERESALSLASTGGYTD 148
Query: 90 TVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGL 149
V LLL E +++ P+ A R NH +C+ LL GAD+T E + G T +
Sbjct: 149 IVGLLL----ERDVDINIYDWNGGTPLLYAVRGNHVKCVEALLARGADLTTEADSGYTPM 204
Query: 150 HVAMEYG 156
+A+ G
Sbjct: 205 DLAVALG 211
>Hs18254476 [R] KOG0504 FOG: Ankyrin repeat
Length = 329
Score = 52.4 bits (124), Expect = 9e-07
Identities = 56/223 (25%), Positives = 91/223 (40%), Gaps = 14/223 (6%)
Query: 6 RIRLREAIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHD 65
R L EA QG+L +R +L + ++ N + + + LH A R L++ G +
Sbjct: 71 RSPLHEAASQGRLLALRTLLSQGYNV--NAVTLDHVTPLHEACLGDHVACARTLLEAGAN 128
Query: 66 ATAMLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHS 125
A+ T DG T + A ++G LLL++ + L S P H A H
Sbjct: 129 VNAI--TIDGVTPLFNACSQGSPSCAELLLEYGAKAQLESCLPS-----PTHEAASKGHH 181
Query: 126 RCLALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCGGATLADEQNQMGIVARQ 185
CL +L+ G DV E T L+VA C+ LL G + + A
Sbjct: 182 ECLDILISWGIDVDQEIPHLGTPLYVACMSQQFHCIWKLLYAGADVQKGKYWDTPLHAAA 241
Query: 186 VGNCDETIKKFDQFAAEIRKGVSSGSSTVPIGTPDIAASKTFL 228
+ E + +F A+I + +T + D+A S + +
Sbjct: 242 QQSSTEIVNLLLEFGADI-----NAKNTELLRPIDVATSSSMV 279
Score = 50.1 bits (118), Expect = 5e-06
Identities = 49/156 (31%), Positives = 66/156 (41%), Gaps = 7/156 (4%)
Query: 13 IVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKT 72
IV+G RI + + + S S LH AA GR L R L+ G++ A+ T
Sbjct: 43 IVKGNRKEAARIAAEFYGVTQGQGSWADRSPLHEAASQGRLLALRTLLSQGYNVNAV--T 100
Query: 73 YDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLL 132
D T +H A GD L LE G N+ + + P+ AC C LLL
Sbjct: 101 LDHVTPLHEACL-GDHVACARTL---LEAGANVNAITIDGVTPLFNACSQGSPSCAELLL 156
Query: 133 QCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCG 168
+ GA LE + H A G +CL IL+ G
Sbjct: 157 EYGAKAQLESCLPSP-THEAASKGHHECLDILISWG 191
>At1g05640 [R] KOG0504 FOG: Ankyrin repeat
Length = 627
Score = 52.4 bits (124), Expect = 9e-07
Identities = 47/182 (25%), Positives = 88/182 (47%), Gaps = 11/182 (6%)
Query: 12 AIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLK 71
A QG + ++++L+ +P+L +D + ++LH AA G + L++ + K
Sbjct: 195 AAKQGHIEALKKLLETFPNLAMTVD-LSCTTALHTAASQGHTDVVNLLLKTDSHLAKIAK 253
Query: 72 TYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRS-NHSRCLAL 130
+G T +H A G + V L+ + + + R+ + A +H+A + N L L
Sbjct: 254 N-NGKTALHSAARMGHREVVKSLIGN--DASIGFRTDKKGQTA-LHMAVKGQNEGIVLEL 309
Query: 131 LLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCGGATLADEQNQMG----IVARQV 186
+ A +++ED +GNT LH A G I+ + L+ G L + N+ G +A ++
Sbjct: 310 VKPDPAILSVEDSKGNTPLHTATNKGRIKIVRCLVSFDGINL-NAMNKAGDTALDIAEKI 368
Query: 187 GN 188
GN
Sbjct: 369 GN 370
>7295892 [M] KOG4177 Ankyrin
Length = 342
Score = 52.0 bits (123), Expect = 1e-06
Identities = 38/129 (29%), Positives = 65/129 (49%), Gaps = 6/129 (4%)
Query: 40 GWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQTVHLLLQHFL 99
G + L +AA G + + LI+ G A+ + DG T + +A G + V LL
Sbjct: 97 GTTPLFFAAQGGHLDVVKILIKAG--ASVDTPSADGGTPLFVACQGGHVKIVRELL---- 150
Query: 100 EEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAMEYGAIQ 159
+ G N+ + R P+ I+ ++ H L+LL+Q GA++ ++ +G T L +A + G
Sbjct: 151 DCGANVNAHMKDRATPVFISAQNGHRTVLSLLIQAGAEIDIKRIDGATPLWIAAQMGQDH 210
Query: 160 CLPILLQCG 168
+LLQ G
Sbjct: 211 ICKVLLQNG 219
>Hs22059561 [R] KOG0504 FOG: Ankyrin repeat
Length = 301
Score = 51.6 bits (122), Expect = 2e-06
Identities = 42/160 (26%), Positives = 71/160 (44%), Gaps = 8/160 (5%)
Query: 9 LREAIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATA 68
L A G + VR ++ + D+ N+ +G ++L +AA G + R L G A+
Sbjct: 50 LMVAAYAGHIDCVRELVLQGADI--NLQRESGTTALFFAAQQGHNDVVRFLFGFG--AST 105
Query: 69 MLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCL 128
+T DG T + A G Q V LL+H G N+ + +A + + +
Sbjct: 106 EFRTKDGGTALLAASQYGHMQVVETLLKH----GANIHDQLYDGATALFLAAQGGYLDVI 161
Query: 129 ALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCG 168
LLL GA V ++G L +A + G + + ++L G
Sbjct: 162 RLLLASGAKVNQPRQDGTAPLWIASQMGHSEVVRVMLLRG 201
>Hs22051029 [T] KOG0705 GTPase-activating protein Centaurin gamma (contains
Ras-like GTPase PH and ankyrin repeat domains)
Length = 663
Score = 51.6 bits (122), Expect = 2e-06
Identities = 32/91 (35%), Positives = 42/91 (45%), Gaps = 2/91 (2%)
Query: 80 HLAITKGDE--QTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGAD 137
HL DE QT LLL H E +N +H+ACR + LL+ G D
Sbjct: 567 HLLRATADEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLAQLLIWYGVD 626
Query: 138 VTLEDEEGNTGLHVAMEYGAIQCLPILLQCG 168
V D GNT L A + + +C+ +LLQ G
Sbjct: 627 VMARDAHGNTALTYARQASSQECINVLLQYG 657
>At2g17390 [R] KOG0504 FOG: Ankyrin repeat
Length = 344
Score = 51.6 bits (122), Expect = 2e-06
Identities = 35/126 (27%), Positives = 58/126 (45%), Gaps = 5/126 (3%)
Query: 76 DTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCG 135
++ +H + GD + L+ L G N + +H AC RC +LL G
Sbjct: 221 ESIVHQTASLGDVEG----LKAALASGGNKDEEDSEGRTALHFACGYGEVRCAQVLLDAG 276
Query: 136 ADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCGGA-TLADEQNQMGIVARQVGNCDETIK 194
A+ D+ NT LH A YG +C+ +LL+ G A T + N+ I ++ N + +K
Sbjct: 277 ANANAIDKNKNTPLHYAAGYGRKECVSLLLENGAAVTQQNMDNKNPIDVARLNNQLDVVK 336
Query: 195 KFDQFA 200
++ A
Sbjct: 337 LLEKDA 342
>Hs7662484 [T] KOG0705 GTPase-activating protein Centaurin gamma (contains
Ras-like GTPase PH and ankyrin repeat domains)
Length = 804
Score = 51.2 bits (121), Expect = 2e-06
Identities = 31/91 (34%), Positives = 43/91 (47%), Gaps = 2/91 (2%)
Query: 80 HLAITKGDE--QTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGAD 137
HL DE +T LLL H + +N +H+ACR + LL+ G D
Sbjct: 682 HLLRATADEDLRTAILLLAHGSRDEVNETCGEGDGRTALHLACRKGNVVLAQLLIWYGVD 741
Query: 138 VTLEDEEGNTGLHVAMEYGAIQCLPILLQCG 168
VT D GNT L A + + +C+ +LLQ G
Sbjct: 742 VTARDAHGNTALAYARQASSQECIDVLLQYG 772
>Hs14150037 [R] KOG0504 FOG: Ankyrin repeat
Length = 422
Score = 51.2 bits (121), Expect = 2e-06
Identities = 32/107 (29%), Positives = 53/107 (48%), Gaps = 4/107 (3%)
Query: 75 GDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQC 134
G+T +H A + + LLL G+++ W P+H AC ++ C+ +LQ
Sbjct: 171 GETALHRACINNQVEKLILLLSL---PGIDINVKDNAGWTPLHEACNYGNTVCVQEILQR 227
Query: 135 GADVTLEDE-EGNTGLHVAMEYGAIQCLPILLQCGGATLADEQNQMG 180
+V L + +G T LH A+ G ++ +LLQ GG L ++N G
Sbjct: 228 CPEVDLLTQVDGVTPLHDALSNGHVEIGKLLLQHGGPVLLQQRNAKG 274
>At2g26650 [PT] KOG0498 K+-channel ERG and related proteins contain PAS/PAC
sensor domain
Length = 857
Score = 51.2 bits (121), Expect = 2e-06
Identities = 34/122 (27%), Positives = 56/122 (45%), Gaps = 1/122 (0%)
Query: 93 LLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVA 152
LLL L+ GL+ S P+HIA C+ LLL+ AD D EG+ L A
Sbjct: 532 LLLHQLLKRGLDPNESDNNGRTPLHIAASKGTLNCVLLLLEYHADPNCRDAEGSVPLWEA 591
Query: 153 MEYGAIQCLPILLQCGGATLADEQNQMGIVARQVGNCDETIKKFDQFAAEIRKGVSSGSS 212
M G + + +LL+ G A + A + GN + +K+ ++ + ++G+S
Sbjct: 592 MVEGHEKVVKVLLEHGSTIDAGDVGHFACTAAEQGNL-KLLKEIVLHGGDVTRPRATGTS 650
Query: 213 TV 214
+
Sbjct: 651 AL 652
>At2g03430 [O] KOG4412 26S proteasome regulatory complex subunit PSMD10
Length = 247
Score = 51.2 bits (121), Expect = 2e-06
Identities = 31/95 (32%), Positives = 46/95 (47%), Gaps = 1/95 (1%)
Query: 74 DGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQ 133
DG + +H+A + G Q V LL E + S WAP+H A ++ + +LL
Sbjct: 46 DGRSLLHVAASFGHSQIVKLLSSSD-EAKTVINSKDDEGWAPLHSAASIGNAELVEVLLT 104
Query: 134 CGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCG 168
GADV ++ G T LH A G ++ +LL G
Sbjct: 105 RGADVNAKNNGGRTALHYAASKGRLEIAQLLLTHG 139
>7301689 [R] KOG0504 FOG: Ankyrin repeat
Length = 2119
Score = 51.2 bits (121), Expect = 2e-06
Identities = 38/137 (27%), Positives = 59/137 (42%), Gaps = 10/137 (7%)
Query: 29 PDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDE 88
PDL + + T W+ A G + + L+ G M +G T + + +G+
Sbjct: 1478 PDLADFMGRTPLWA----ACTAGHATVVKLLLFWGCGIDCM--DSEGRTVLSIGAAQGNV 1531
Query: 89 QTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTG 148
+TV LL + GL+ W P+H A LL+ GA + D EG T
Sbjct: 1532 ETVRQLL----DRGLDETHRDNAGWTPLHYAAFEGFHEVCLQLLESGAKIDECDNEGKTA 1587
Query: 149 LHVAMEYGAIQCLPILL 165
LH+A + G + C+ LL
Sbjct: 1588 LHLAAQEGRLHCVQALL 1604
>7295029 [R] KOG0510 Ankyrin repeat protein
Length = 1274
Score = 51.2 bits (121), Expect = 2e-06
Identities = 43/135 (31%), Positives = 63/135 (45%), Gaps = 6/135 (4%)
Query: 31 LLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAITKGDEQT 90
LL N + G S LHYA+ G +LI+LG A LK + ++ +H A G T
Sbjct: 455 LLLNEKDSMGCSPLHYASRDGHIRSLENLIRLG--ACINLKNNNNESPLHFAARYGRYNT 512
Query: 91 VHLLLQHFLEEG-LNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGL 149
V LL E+G + S P+HI+ + H+R + LLL GA + D G L
Sbjct: 513 VRQLLDS--EKGSFIINESDGAGMTPLHISSQQGHTRVVQLLLNRGA-LLHRDHTGRNPL 569
Query: 150 HVAMEYGAIQCLPIL 164
+A G + + +L
Sbjct: 570 QLAAMSGYTETIELL 584
Score = 50.4 bits (119), Expect = 4e-06
Identities = 39/138 (28%), Positives = 66/138 (47%), Gaps = 9/138 (6%)
Query: 34 NIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGD--TCIHLAITKGDEQTV 91
N+ + N S LH+AA YGRY R L+ + ++ DG T +H++ +G + V
Sbjct: 491 NLKNNNNESPLHFAARYGRYNTVRQLLD-SEKGSFIINESDGAGMTPLHISSQQGHTRVV 549
Query: 92 HLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLE-DEEGNTGLH 150
LLL L R + R P+ +A S ++ + LL + + + D++GNT LH
Sbjct: 550 QLLLN---RGALLHRDHTGRN--PLQLAAMSGYTETIELLHSVHSHLLDQVDKDGNTALH 604
Query: 151 VAMEYGAIQCLPILLQCG 168
+A + +L+ G
Sbjct: 605 LATMENKPHAISVLMSMG 622
>7291939 [R] KOG0510 Ankyrin repeat protein
Length = 904
Score = 51.2 bits (121), Expect = 2e-06
Identities = 55/194 (28%), Positives = 90/194 (46%), Gaps = 12/194 (6%)
Query: 4 EPRIRLREAIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLG 63
E R L AI + V +LK D N + LH A+ G + C L+ L
Sbjct: 205 EKRSALHYAIDVNAVDCVEILLKYGAD--PNTPQVYTETPLHTASAAG-FAKCVQLL-LS 260
Query: 64 HDATAMLKTYDGD-TCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRS 122
H+A + +G T +HLA + LLL+H E ++ R++S + P+H+AC S
Sbjct: 261 HNADVRSQFGEGKVTALHLAAENDYVECARLLLEHRAE--VDCRNASHQ--TPLHLACLS 316
Query: 123 NHSRCLALLLQCGADVTLEDEEGNTGLHVAM--EYGAIQCLPILLQCGGATLADEQNQMG 180
+ LL+ GA+V +G T LH A+ + ++ C LL+ GA + + +
Sbjct: 317 QSIGTVDLLISYGANVNAVYRDGRTALHAAIVKQSRSLDCCNALLK-AGADVNKLDSSIK 375
Query: 181 IVARQVGNCDETIK 194
+++G+ D IK
Sbjct: 376 ANDQEIGDVDCQIK 389
>Hs7705278_2 [R] KOG0504 FOG: Ankyrin repeat
Length = 860
Score = 51.2 bits (121), Expect = 2e-06
Identities = 36/142 (25%), Positives = 66/142 (46%), Gaps = 5/142 (3%)
Query: 24 ILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCIHLAI 83
ILKR E +D+ G +SLH A LI + + + + T +HL +
Sbjct: 547 ILKRGSGAAEQVDN-KGRNSLHVAVQNSDIESVLSLISVHANVNSRAQDAPKLTPLHLVV 605
Query: 84 TKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDE 143
+G E +++++ L G + + R +H+A + + ++LL+ D DE
Sbjct: 606 QEGSE----IIVRNLLLAGAKVTELTKHRKTALHLAAQEDLPTICSVLLENAVDFAAVDE 661
Query: 144 EGNTGLHVAMEYGAIQCLPILL 165
GN LH+A+ +G + + +LL
Sbjct: 662 NGNNALHLAVMHGRLNNIRVLL 683
>Hs19923223_2 [R] KOG0504 FOG: Ankyrin repeat
Length = 451
Score = 51.2 bits (121), Expect = 2e-06
Identities = 47/156 (30%), Positives = 75/156 (47%), Gaps = 14/156 (8%)
Query: 9 LREAIVQGKLGVVRRI---LKRWPDL-LENIDSTNGWSSLHYAAFYGRYLICRHLIQLGH 64
L AI+ G+ V+ +I + DL + N+ + + LH A G+ + L+++G
Sbjct: 9 LHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAVITGQTSVVSFLLRVGA 68
Query: 65 DATAMLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLN-----LRSSSARRWAPIHIA 119
D A+L + GD+ +HLA+ G LL+ L+ G L P+H+A
Sbjct: 69 DP-ALLDRH-GDSAMHLALRAGAGAPE--LLRALLQSGAPAVPQLLHMPDFEGLYPVHLA 124
Query: 120 CRSNHSRCLALLLQCGADV-TLEDEEGNTGLHVAME 154
R+ CL LL+ GA+V E + G T LH+A E
Sbjct: 125 VRARSPECLDLLVDSGAEVEATERQGGRTALHLATE 160
>Hs22053338 [T] KOG0705 GTPase-activating protein Centaurin gamma (contains
Ras-like GTPase PH and ankyrin repeat domains)
Length = 663
Score = 50.8 bits (120), Expect = 3e-06
Identities = 29/82 (35%), Positives = 39/82 (47%)
Query: 87 DEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGN 146
D QT LLL H E +N +H+ACR + LL+ G DV D GN
Sbjct: 576 DLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGN 635
Query: 147 TGLHVAMEYGAIQCLPILLQCG 168
T L A + + +C+ +LLQ G
Sbjct: 636 TALTYARQASSQECINVLLQYG 657
>Hs22051953 [T] KOG0705 GTPase-activating protein Centaurin gamma (contains
Ras-like GTPase PH and ankyrin repeat domains)
Length = 663
Score = 50.8 bits (120), Expect = 3e-06
Identities = 29/82 (35%), Positives = 39/82 (47%)
Query: 87 DEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGN 146
D QT LLL H E +N +H+ACR + LL+ G DV D GN
Sbjct: 576 DLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGN 635
Query: 147 TGLHVAMEYGAIQCLPILLQCG 168
T L A + + +C+ +LLQ G
Sbjct: 636 TALTYARQASSQECINVLLQYG 657
>Hs20547087 [T] KOG0705 GTPase-activating protein Centaurin gamma (contains
Ras-like GTPase PH and ankyrin repeat domains)
Length = 439
Score = 50.8 bits (120), Expect = 3e-06
Identities = 29/82 (35%), Positives = 39/82 (47%)
Query: 87 DEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGN 146
D QT LLL H E +N +H+ACR + LL+ G DV D GN
Sbjct: 352 DLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGN 411
Query: 147 TGLHVAMEYGAIQCLPILLQCG 168
T L A + + +C+ +LLQ G
Sbjct: 412 TALTYARQASSQECINVLLQYG 433
>Hs19263343 [T] KOG0705 GTPase-activating protein Centaurin gamma (contains
Ras-like GTPase PH and ankyrin repeat domains)
Length = 663
Score = 50.8 bits (120), Expect = 3e-06
Identities = 29/82 (35%), Positives = 39/82 (47%)
Query: 87 DEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGN 146
D QT LLL H E +N +H+ACR + LL+ G DV D GN
Sbjct: 576 DLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGN 635
Query: 147 TGLHVAMEYGAIQCLPILLQCG 168
T L A + + +C+ +LLQ G
Sbjct: 636 TALTYARQASSQECINVLLQYG 657
>Hs17485543 [R] KOG0504 FOG: Ankyrin repeat
Length = 353
Score = 50.8 bits (120), Expect = 3e-06
Identities = 40/128 (31%), Positives = 57/128 (44%), Gaps = 7/128 (5%)
Query: 39 NGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCI-HLAITKGDEQTVHLLLQH 97
+G +++H A L+ LG A+ K G T + H A+ GD LLL
Sbjct: 182 DGLTAVHCATRQRNAAALTTLLDLG--ASPDYKDSRGLTPLYHSALGGGDALCCELLLHD 239
Query: 98 FLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVAMEYGA 157
+ G+ + W IH ACR H + L LL GAD+ ++ GNT LH+ Y
Sbjct: 240 HAQLGI----TDENGWQEIHQACRFGHVQHLEHLLFYGADMGAQNASGNTALHICALYNQ 295
Query: 158 IQCLPILL 165
C +LL
Sbjct: 296 ESCARVLL 303
>Hs20270347 [R] KOG0504 FOG: Ankyrin repeat
Length = 300
Score = 50.4 bits (119), Expect = 4e-06
Identities = 49/164 (29%), Positives = 68/164 (40%), Gaps = 15/164 (9%)
Query: 4 EPRIRLREAIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLG 63
EPR LR I G+L RR + L + L +A + L++ G
Sbjct: 77 EPRDELRCKIPAGRL---RRAARPHRRLGPTGKEVHALKRLRDSANANDVETVQQLLEDG 133
Query: 64 HDATAMLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSN 123
D A G T +H A G++Q V LLL H G + P+H+A +N
Sbjct: 134 ADPCAA--DDKGRTALHFASCNGNDQIVQLLLDH----GADPNQRDGLGNTPLHLAACTN 187
Query: 124 HSRCLALLLQCGADVTLEDEEGNTGLHVA------MEYGAIQCL 161
H + LL+ GA V D G T LH+A ++ G QCL
Sbjct: 188 HVPVITTLLRGGARVDALDRAGRTPLHLAKSKLNILQEGHAQCL 231
>Hs10092619 [R] KOG0504 FOG: Ankyrin repeat
Length = 317
Score = 50.4 bits (119), Expect = 4e-06
Identities = 29/95 (30%), Positives = 46/95 (47%)
Query: 72 TYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALL 131
T DGD+ +HLAI ++ +++ + L + + P+H+A +N L
Sbjct: 71 TEDGDSFLHLAIIHEEKALTMEVIRQVKGDLAFLNFQNNLQQTPLHLAVITNQPEIAEAL 130
Query: 132 LQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQ 166
L G D L D GNT LH+A E G + + +L Q
Sbjct: 131 LGAGCDPELRDFRGNTPLHLACEQGCLASVGVLTQ 165
>At4g35450 [R] KOG0504 FOG: Ankyrin repeat
Length = 342
Score = 50.4 bits (119), Expect = 4e-06
Identities = 34/126 (26%), Positives = 58/126 (45%), Gaps = 5/126 (3%)
Query: 76 DTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCG 135
++ +H + GD + L+ L G N + +H AC +C +L+ G
Sbjct: 219 ESIVHQTASLGDVEG----LKAALASGGNKDEEDSEGRTALHFACGYGELKCAQVLIDAG 274
Query: 136 ADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCGGA-TLADEQNQMGIVARQVGNCDETIK 194
A V D+ NT LH A YG +C+ +LL+ G A TL + + I ++ + E +K
Sbjct: 275 ASVNAVDKNKNTPLHYAAGYGRKECVSLLLENGAAVTLQNLDEKTPIDVAKLNSQLEVVK 334
Query: 195 KFDQFA 200
++ A
Sbjct: 335 LLEKDA 340
>Hs7661962 [T] KOG0705 GTPase-activating protein Centaurin gamma (contains
Ras-like GTPase PH and ankyrin repeat domains)
Length = 836
Score = 50.1 bits (118), Expect = 5e-06
Identities = 32/87 (36%), Positives = 41/87 (46%)
Query: 82 AITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLE 141
A+ D TV LLL H L+ + +P+H+A H LLL GADV
Sbjct: 705 AVQAQDVATVLLLLAHARHGPLDTSVEDPQLRSPLHLAAELAHVVITQLLLWYGADVAAR 764
Query: 142 DEEGNTGLHVAMEYGAIQCLPILLQCG 168
D +G T L A + G+ C ILLQ G
Sbjct: 765 DAQGRTALFYARQAGSQLCADILLQHG 791
>Hs22051601 [R] KOG0514 Ankyrin repeat protein
Length = 454
Score = 50.1 bits (118), Expect = 5e-06
Identities = 39/154 (25%), Positives = 72/154 (46%), Gaps = 2/154 (1%)
Query: 13 IVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKT 72
+V+ L R + R D + NI +NG ++LHY+ + + + + L+ G
Sbjct: 253 LVRRHLVTFRAMSARLLDYVVNIADSNGNTALHYSVSHANFPVVQQLLDSGVCKVDKQNR 312
Query: 73 YDGDTCIHLAI-TKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALL 131
+ A+ T + + +LQ F +N ++S A + A + +A + L
Sbjct: 313 AGYSPIMLTALATLKTQDDIETVLQLFRLGNINAKASQAGQTA-LMLAVSHGRVDVVKAL 371
Query: 132 LQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILL 165
L C ADV ++D++G+T L A E+G + +LL
Sbjct: 372 LACEADVNVQDDDGSTALMCACEHGHKEIAGLLL 405
>Hs20547911 [T] KOG0705 GTPase-activating protein Centaurin gamma (contains
Ras-like GTPase PH and ankyrin repeat domains)
Length = 550
Score = 50.1 bits (118), Expect = 5e-06
Identities = 31/91 (34%), Positives = 42/91 (46%), Gaps = 2/91 (2%)
Query: 80 HLAITKGDE--QTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGAD 137
HL DE +T LLL H E +N +H+ACR + LL+ G D
Sbjct: 454 HLLRATADEDLRTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLAQLLIWYGVD 513
Query: 138 VTLEDEEGNTGLHVAMEYGAIQCLPILLQCG 168
V D GNT L A + + +C+ +LLQ G
Sbjct: 514 VMARDAHGNTALTYARQASSQECINVLLQYG 544
>Hs20543681 [T] KOG0705 GTPase-activating protein Centaurin gamma (contains
Ras-like GTPase PH and ankyrin repeat domains)
Length = 485
Score = 50.1 bits (118), Expect = 5e-06
Identities = 29/82 (35%), Positives = 39/82 (47%)
Query: 87 DEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGN 146
D QT LLL H E +N +H+ACR + LL+ G DV D GN
Sbjct: 398 DLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLEQLLIWYGVDVMARDAHGN 457
Query: 147 TGLHVAMEYGAIQCLPILLQCG 168
T L A + + +C+ +LLQ G
Sbjct: 458 TALTYARQASSQECINVLLQYG 479
>Hs14738291 [R] KOG0504 FOG: Ankyrin repeat
Length = 1554
Score = 50.1 bits (118), Expect = 5e-06
Identities = 58/215 (26%), Positives = 89/215 (40%), Gaps = 15/215 (6%)
Query: 9 LREAIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATA 68
L A +GKL V +L + + G L AA G + I R L++ G D
Sbjct: 776 LTAAAGRGKLEVCELLLGHGAAVSRT--NRRGVPPLFCAARQGHWQIVRLLLERGCDVN- 832
Query: 69 MLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCL 128
L G T + +A +G TV LL +G L S + + AC H +
Sbjct: 833 -LSDKQGRTPLMVAACEGHLSTVEFLLS----KGAALSSLDKEGLSALSWACLKGHRAVV 887
Query: 129 ALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCGGATLADEQNQMGIVARQVGN 188
L++ GA + D+ G T L +A YG + + L++ G + + M + R +G
Sbjct: 888 QYLVEEGAAIDQTDKNGRTPLDLAAFYGDAETVLYLVEKGAVIEHVDHSGMRPLDRAIG- 946
Query: 189 CDETIKKFDQFAAEIRKGVSSGSSTVPIGT--PDI 221
C T A +RKG G++ + T PDI
Sbjct: 947 CRNT----SVVVALLRKGAKLGNAAWAMATSKPDI 977
Score = 49.3 bits (116), Expect = 8e-06
Identities = 32/96 (33%), Positives = 47/96 (48%), Gaps = 4/96 (4%)
Query: 75 GDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQC 134
G+T + A +G + LLL H G + ++ R P+ A R H + + LLL+
Sbjct: 772 GETALTAAAGRGKLEVCELLLGH----GAAVSRTNRRGVPPLFCAARQGHWQIVRLLLER 827
Query: 135 GADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCGGA 170
G DV L D++G T L VA G + + LL G A
Sbjct: 828 GCDVNLSDKQGRTPLMVAACEGHLSTVEFLLSKGAA 863
>7301132 [R] KOG0504 FOG: Ankyrin repeat
Length = 784
Score = 50.1 bits (118), Expect = 5e-06
Identities = 44/160 (27%), Positives = 74/160 (45%), Gaps = 7/160 (4%)
Query: 9 LREAIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATA 68
L EA G L +V+ +L D+ N G + L +A G+ + + L++ H A
Sbjct: 33 LMEAASAGHLDIVKLLLNHNADV--NAHCATGNTPLMFACAGGQVDVVKVLLK--HGANV 88
Query: 69 MLKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCL 128
+ +G T + A + G + +LL+H G+N S+ + A + +AC H +
Sbjct: 89 EEQNENGHTPLMEAASAGHVEVAKVLLEH--GAGINTHSNEFKESA-LTLACYKGHLDMV 145
Query: 129 ALLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCG 168
LLQ GAD + +E +T L A G ++ +LL G
Sbjct: 146 RFLLQAGADQEHKTDEMHTALMEASMDGHVEVARLLLDSG 185
>Hs7657238 [R] KOG0504 FOG: Ankyrin repeat
Length = 1065
Score = 49.7 bits (117), Expect = 6e-06
Identities = 46/206 (22%), Positives = 82/206 (39%), Gaps = 35/206 (16%)
Query: 4 EPRIRLREAIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQ-- 61
E R A +G V+R +L D+ N+ G ++LH AA G + L++
Sbjct: 321 EGRTSFMWAAGKGSDDVLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLLLENN 380
Query: 62 -------------------LGHD----------ATAMLKTYDGDTCIHLAITKGDEQTVH 92
+GH A L DG + +H A G+
Sbjct: 381 AQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNADVCQ 440
Query: 93 LLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVTLEDEEGNTGLHVA 152
+L+++ + N++ + R P+ A + C+A+L++ AD ++D+EG T LH +
Sbjct: 441 ILIENKINP--NVQDYAGR--TPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWS 496
Query: 153 MEYGAIQCLPILLQCGGATLADEQNQ 178
G + + +LL E N+
Sbjct: 497 CNNGYLDAIKLLLDFAAFPNQMENNE 522
>At2g01680 [R] KOG0504 FOG: Ankyrin repeat
Length = 532
Score = 49.7 bits (117), Expect = 6e-06
Identities = 42/157 (26%), Positives = 74/157 (46%), Gaps = 10/157 (6%)
Query: 12 AIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLK 71
A +G LG+V+ +L+ WP+L D++N S L+ AA I ++ + + AM+
Sbjct: 101 AAKRGHLGIVKELLRLWPELCRICDASN-TSPLYAAAVQDHLEIVNAMLDV-DPSCAMIV 158
Query: 72 TYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALL 131
+G T +H A G + V L++ ++ + + +H+A + + +
Sbjct: 159 RKNGKTSLHTAGRYGLLRIVKALIE---KDAAIVGVKDKKGQTALHMAVKGRSLEVVEEI 215
Query: 132 LQCGADVTL---EDEEGNTGLHVAMEYGAIQCLPILL 165
LQ AD T+ D +GNT LH+A Q +LL
Sbjct: 216 LQ--ADYTILNERDRKGNTALHIATRKARPQITSLLL 250
>7299952 [R] KOG0508 Ankyrin repeat protein
Length = 662
Score = 49.7 bits (117), Expect = 6e-06
Identities = 47/177 (26%), Positives = 67/177 (37%), Gaps = 45/177 (25%)
Query: 12 AIVQGKLGVVRRILKRWPDLLENIDSTNGWSS--LHYAAFYGRYLICRHLIQLGHDATAM 69
A G LG+V+ +++R N++ST +S L A F G Y I ++L+ H A
Sbjct: 88 AAAAGHLGIVKMLVRRGA----NVNSTTRTNSTPLRAACFDGHYEIVKYLVH--HGADFE 141
Query: 70 LKTYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLA 129
+ G TC+ IAC H R
Sbjct: 142 VANRHGHTCLM-------------------------------------IACYKGHFRIAQ 164
Query: 130 LLLQCGADVTLEDEEGNTGLHVAMEYGAIQCLPILLQCGGATLADEQNQMGIVARQV 186
LL ADV +GNT LH E G++Q L +LL+ G D ++A V
Sbjct: 165 YLLSLNADVNRCSVKGNTALHDCAESGSLQILQLLLKHGATMDVDYYGMTPLLAASV 221
>SPAC6C3.08 [O] KOG4412 26S proteasome regulatory complex subunit PSMD10
Length = 234
Score = 49.3 bits (116), Expect = 8e-06
Identities = 41/148 (27%), Positives = 63/148 (41%), Gaps = 8/148 (5%)
Query: 20 VVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLKTYDGDTCI 79
V+ ++ R D+ I + G + LHYAA GR I + L + K G T +
Sbjct: 88 VIEELINR-SDVDPTITTRGGQTCLHYAAGKGRLSIVQLLCDKAPELIRK-KDLQGQTPL 145
Query: 80 HLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADVT 139
H A G Q V ++ + + L +S + + P+H A H L++ GAD
Sbjct: 146 HRAAAVGKIQVV----KYLISQRAPLNTSDSYGFTPLHFALAEGHPDVGVELVRAGADTL 201
Query: 140 LEDEEGNTGLHVAMEYGAIQCLPILLQC 167
+D E +T L V + I C L C
Sbjct: 202 RKDSENHTALEVCPD--RIVCNEFLEAC 227
>Hs14742395 [R] KOG0514 Ankyrin repeat protein
Length = 1194
Score = 49.3 bits (116), Expect = 8e-06
Identities = 47/175 (26%), Positives = 84/175 (47%), Gaps = 20/175 (11%)
Query: 29 PDLLE---NIDSTNGWSSLHYAAFYGRYLICRHLIQ-----LGHDATAMLKTYDGDTCIH 80
PD+L N+ NG ++LHY+ + + I + L+ + H A G T I
Sbjct: 990 PDVLRYVINLADGNGNTALHYSVSHSNFEIVKLLLDADVCNVDHQNKA------GYTPIM 1043
Query: 81 LAITKG--DEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALLLQCGADV 138
LA E+ + ++ + F +N ++S A + A + +A + LL CGADV
Sbjct: 1044 LAALAAVEAEKDMRIVEELFGCGDVNAKASQAGQTA-LMLAVSHGRIDMVKGLLACGADV 1102
Query: 139 TLEDEEGNTGLHVAMEYGAIQCLPILLQ---CGGATLADEQNQMGIVARQVGNCD 190
++D+EG+T L A E+G ++ + +LL C G ++ + +A + G+ D
Sbjct: 1103 NIQDDEGSTALMCASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEAGHKD 1157
>At2g31820 [R] KOG0504 FOG: Ankyrin repeat
Length = 662
Score = 49.3 bits (116), Expect = 8e-06
Identities = 47/184 (25%), Positives = 89/184 (47%), Gaps = 11/184 (5%)
Query: 12 AIVQGKLGVVRRILKRWPDLLENIDSTNGWSSLHYAAFYGRYLICRHLIQLGHDATAMLK 71
A QG L V++ +L+ +P+L D + ++LH AA G + L++ + + K
Sbjct: 231 AAKQGHLEVLKILLETFPNLAMTTD-LSCTTALHTAATQGHIDVVNLLLETDSNLAKIAK 289
Query: 72 TYDGDTCIHLAITKGDEQTVHLLLQHFLEEGLNLRSSSARRWAPIHIACRSNHSRCLALL 131
+G T +H A G + V L+ + + R+ + A +H+A + + + L
Sbjct: 290 N-NGKTALHSAARMGHVEVVKSLIGK--DPSIGFRTDKKGQTA-LHMAVKGQNDGIVVEL 345
Query: 132 LQCGADV-TLEDEEGNTGLHVAMEYGAIQCLPILLQCGGATLADEQNQMG----IVARQV 186
++ V ++ED +GNT LH+A G I+ + L+ G L + N+ G V+ ++
Sbjct: 346 VKPDVAVLSVEDNKGNTPLHIATNKGRIKIVRCLVSFEGINL-NPINKAGDTPLDVSEKI 404
Query: 187 GNCD 190
GN +
Sbjct: 405 GNAE 408
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.318 0.136 0.404
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,820,750
Number of Sequences: 60738
Number of extensions: 822065
Number of successful extensions: 4681
Number of sequences better than 1.0e-05: 121
Number of HSP's better than 0.0 without gapping: 23
Number of HSP's successfully gapped in prelim test: 102
Number of HSP's that attempted gapping in prelim test: 3378
Number of HSP's gapped (non-prelim): 676
length of query: 336
length of database: 30,389,216
effective HSP length: 107
effective length of query: 229
effective length of database: 23,890,250
effective search space: 5470867250
effective search space used: 5470867250
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)