ORF      STATUS       Function Best COG  Functional category                                          Pathways and functional systems
r_klactVI7005   suspect: LH   U     KOG3028  Intracellular trafficking, secretion, and vesicular transport  Translocase of outer mitochondrial membrane complex, subunit TOM37/Metaxin 1

BLASTP 2.2.3 [May-13-2002]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= r_klactVI7005 2438840  2439742 301  
         (301 letters)

Database: KOG eukaryal database 04/03 
           60,738 sequences; 30,389,216 total letters

Searching..................................................done

Color Key for Alignment Scores:   


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

YMR060c [U] KOG3028 Translocase of outer mitochondrial membrane ...   202   4e-52

>YMR060c [U] KOG3028 Translocase of outer mitochondrial membrane complex
           subunit TOM37/Metaxin 1
          Length = 327

 Score =  202 bits (515), Expect = 4e-52
 Identities = 123/321 (38%), Positives = 195/321 (60%), Gaps = 43/321 (13%)

Query: 7   LHLWGLNGEPSLVSPESIALCWLLK------GGYVASGTVQVVYSNNTDLSPTGELPILI 60
           +HLWG +G+ SL+S +SIAL W +K         + +G +Q+V+SNNTDLS  G+LP+LI
Sbjct: 6   VHLWGKDGKASLISVDSIALVWFIKLCTSEEAKSMVAG-LQIVFSNNTDLSSDGKLPVLI 64

Query: 61  -DTSAKITVGLYSIIEHLV-------------HDNDV-------KLLSSALLQFISEELK 99
            D   K++ G  +I++ L              ++ D+       +LL  +LL ++  E+ 
Sbjct: 65  LDNGTKVS-GYVNIVQFLHKNICTSKYEKGTDYEEDLAIVRKKDRLLEYSLLNYVDVEIS 123

Query: 100 TCTMYQLYLNPVNYNEYTSKIYSYLLHWPFWYNTPLSARSRARELCRDIM--VTIPEDEE 157
             T YQL+LN  NYNEYT K++S LL++P WYNTPL  RS+ARE C +I+  +T+ +DEE
Sbjct: 124 RLTDYQLFLNTKNYNEYTKKLFSKLLYFPMWYNTPLQLRSQARENCEEIIGSLTLEDDEE 183

Query: 158 NESTSNHQDELSEKATELAQSKVFKITRDSKRQQTKKLQELKNNSRFTTKLDNVLTNWES 217
                  + +  E A++LAQSK FKI   +K +  ++LQ++K N +F  +L + ++NW +
Sbjct: 184 FV-----ESKAMESASQLAQSKTFKIAHKNKIKGKQELQQVKYNLQFDNRLQSCVSNWLA 238

Query: 218 ARQSL-ASAVLPADLVLVAHLKVQMALPQGDLLRSHLRNQY-----PSLYDKVNELIEKY 271
           AR+ L  S +L +DL+ +A+L VQ+ LP G+ +RS L   +      S+ +K+++ + + 
Sbjct: 239 ARKKLDDSVILSSDLLFLANLYVQLGLPDGNRIRSKLEQTFGSELLNSMSNKIDDFVHRP 298

Query: 272 DNSPVPNRDPTFSESGNVVTS 292
            N+ +  RDP F E GNVV S
Sbjct: 299 SNN-LEQRDPQFREQGNVVMS 318


  Database: KOG eukaryal database 04/03
    Posted date:  Apr 14, 2003  1:07 PM
  Number of letters in database: 30,389,216
  Number of sequences in database:  60,738
  
Lambda     K      H
   0.315    0.131    0.378 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,141,625
Number of Sequences: 60738
Number of extensions: 776786
Number of successful extensions: 3201
Number of sequences better than 1.0e-05: 1
Number of HSP's better than  0.0 without gapping: 1
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 3195
Number of HSP's gapped (non-prelim): 1
length of query: 301
length of database: 30,389,216
effective HSP length: 106
effective length of query: 195
effective length of database: 23,950,988
effective search space: 4670442660
effective search space used: 4670442660
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)