ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI7146 check: MH T KOG0585 Signal transduction mechanisms Ca2+/calmodulin-dependent protein kinase kinase beta and related serine/threonine protein kinases
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI7146 2489326 2490726 467
(467 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YKL048c [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 270 4e-72
YGL179c [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 124 2e-28
SPCC297.03 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 122 1e-27
YER129w [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 119 1e-26
At5g60550 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase k... 105 2e-22
CE01146 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 103 7e-22
At3g45240 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase k... 99 1e-20
Hs14150045 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 97 5e-20
At2g25090 [T] KOG0583 Serine/threonine protein kinase 96 1e-19
Hs17933758 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 95 3e-19
7293496 [R] KOG0597 Serine-threonine protein kinase FUSED 94 3e-19
Hs7662170 [R] KOG0611 Predicted serine/threonine protein kinase 94 4e-19
At2g38910 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 94 4e-19
At2g41860 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 92 2e-18
At5g01820 [T] KOG0583 Serine/threonine protein kinase 92 2e-18
Hs4557511 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 91 4e-18
At2g30360 [T] KOG0583 Serine/threonine protein kinase 91 4e-18
At1g12580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 91 4e-18
Hs22043888 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 90 6e-18
At5g04870 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 90 8e-18
At3g01090 [T] KOG0583 Serine/threonine protein kinase 90 8e-18
YDR507c [D] KOG0588 Serine/threonine protein kinase 89 1e-17
SPCC320.12c [D] KOG0580 Serine/threonine protein kinase 89 1e-17
Hs4826684_1 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 89 1e-17
At4g04720 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 89 1e-17
At1g08650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 89 1e-17
At5g01810 [T] KOG0583 Serine/threonine protein kinase 88 2e-17
At2g38490 [T] KOG0583 Serine/threonine protein kinase 88 2e-17
At5g10930 [T] KOG0583 Serine/threonine protein kinase 88 3e-17
At3g10660 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 88 3e-17
At2g35890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 88 3e-17
At4g21940 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 87 4e-17
CE28643 [T] KOG0583 Serine/threonine protein kinase 87 5e-17
CE07458 [T] KOG0583 Serine/threonine protein kinase 87 5e-17
At5g25110 [T] KOG0583 Serine/threonine protein kinase 86 9e-17
7299322 [R] KOG0611 Predicted serine/threonine protein kinase 86 9e-17
At1g50230 [R] KOG0597 Serine-threonine protein kinase FUSED 86 1e-16
CE26793_1 [R] KOG0611 Predicted serine/threonine protein kinase 86 1e-16
Hs5453964 [T] KOG0583 Serine/threonine protein kinase 86 2e-16
Hs13569922 [R] KOG0611 Predicted serine/threonine protein kinase 86 2e-16
7303019 [Z] KOG0613 Projectin/twitchin and related proteins 86 2e-16
At5g58380 [T] KOG0583 Serine/threonine protein kinase 85 2e-16
At5g07070 [T] KOG0583 Serine/threonine protein kinase 85 2e-16
At3g57530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 85 2e-16
At3g29160 [T] KOG0583 Serine/threonine protein kinase 85 2e-16
At3g20410 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 85 2e-16
At1g50700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 85 2e-16
At3g49370 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 85 3e-16
At2g31500 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 85 3e-16
At1g76040 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 84 3e-16
At1g35670 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 84 3e-16
YCL024w [T] KOG0583 Serine/threonine protein kinase 84 5e-16
Hs14777335 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 84 5e-16
At2g41140 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 84 5e-16
Hs14670383 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 84 6e-16
At5g45810 [T] KOG0583 Serine/threonine protein kinase 84 6e-16
At1g74740 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 84 6e-16
YGL180w [OUT] KOG0595 Serine/threonine-protein kinase involved i... 83 8e-16
At5g45820 [T] KOG0583 Serine/threonine protein kinase 83 8e-16
7304311 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 83 8e-16
Hs9845489 [R] KOG0586 Serine/threonine protein kinase 83 1e-15
Hs9845487 [R] KOG0586 Serine/threonine protein kinase 83 1e-15
Hs22062450 [R] KOG0586 Serine/threonine protein kinase 83 1e-15
At5g19450 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 83 1e-15
At3g23000 [T] KOG0583 Serine/threonine protein kinase 83 1e-15
7298652 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 83 1e-15
7290249 [R] KOG0586 Serine/threonine protein kinase 83 1e-15
SPCC1259.13 [D] KOG0590 Checkpoint kinase and related serine/thr... 82 1e-15
CE24761 [D] KOG0580 Serine/threonine protein kinase 82 1e-15
At2g26980 [T] KOG0583 Serine/threonine protein kinase 82 1e-15
At1g62400 [T] KOG0192 Tyrosine kinase specific for activated (GT... 82 1e-15
Hs4507275 [D] KOG0580 Serine/threonine protein kinase 82 2e-15
At1g30270 [T] KOG0583 Serine/threonine protein kinase 82 2e-15
7290150 [T] KOG0583 Serine/threonine protein kinase 82 2e-15
7289880 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 82 2e-15
HsM4507279 [D] KOG0580 Serine/threonine protein kinase 82 2e-15
At3g50530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 82 2e-15
At2g45490 [D] KOG0580 Serine/threonine protein kinase 82 2e-15
At1g01140 [T] KOG0583 Serine/threonine protein kinase 82 2e-15
Hs5453966 [T] KOG0583 Serine/threonine protein kinase 81 3e-15
CE05780 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 81 3e-15
At4g04740 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 81 3e-15
At2g37840 [OUT] KOG0595 Serine/threonine-protein kinase involved... 81 3e-15
At2g24360 [T] KOG0192 Tyrosine kinase specific for activated (GT... 81 3e-15
At1g61950 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 81 3e-15
At5g35410 [T] KOG0583 Serine/threonine protein kinase 81 4e-15
At4g24400 [T] KOG0583 Serine/threonine protein kinase 81 4e-15
At2g25880 [D] KOG0580 Serine/threonine protein kinase 81 4e-15
7302464 [R] KOG0586 Serine/threonine protein kinase 81 4e-15
7299437 [R] KOG0586 Serine/threonine protein kinase 81 4e-15
Hs4502557 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 80 5e-15
Hs21361133 [R] KOG0586 Serine/threonine protein kinase 80 5e-15
At5g19360 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 80 5e-15
At5g12180 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 80 5e-15
At4g36070 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 80 5e-15
At4g30960 [T] KOG0583 Serine/threonine protein kinase 80 5e-15
At4g09570 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 80 5e-15
At2g17890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 80 5e-15
At1g18890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 80 5e-15
YFR014c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 80 6e-15
SPAC1F5.09c [T] KOG0578 p21-activated serine/threonine protein k... 80 6e-15
At4g32830 [D] KOG0580 Serine/threonine protein kinase 80 6e-15
At3g19100 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 80 6e-15
At1g48260 [T] KOG0583 Serine/threonine protein kinase 80 6e-15
7294537 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 80 6e-15
CE18967 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD a... 80 8e-15
At5g23580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 80 8e-15
At4g38230 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 80 8e-15
At3g56760 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 80 8e-15
At3g17510 [T] KOG0583 Serine/threonine protein kinase 80 8e-15
At1g49580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 80 8e-15
Hs4758128_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 80 8e-15
YDR477w [T] KOG0583 Serine/threonine protein kinase 79 1e-14
Hs7657214 [T] KOG0583 Serine/threonine protein kinase 79 1e-14
Hs14916455 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 79 1e-14
At5g57630 [T] KOG0583 Serine/threonine protein kinase 79 1e-14
At4g18700 [T] KOG0583 Serine/threonine protein kinase 79 1e-14
YOL016c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 79 1e-14
HsM4505103 [R] KOG0586 Serine/threonine protein kinase 79 1e-14
ECU01g0630 [D] KOG0575 Polo-like serine/threonine protein kinase 79 1e-14
Hs4507271 [T] KOG0583 Serine/threonine protein kinase 79 2e-14
At1g29230 [T] KOG0583 Serine/threonine protein kinase 79 2e-14
Hs8923922 [R] KOG0586 Serine/threonine protein kinase 78 2e-14
Hs16950621 [Z] KOG0613 Projectin/twitchin and related proteins 78 2e-14
Hs16950613 [Z] KOG0613 Projectin/twitchin and related proteins 78 2e-14
Hs16950611 [Z] KOG0613 Projectin/twitchin and related proteins 78 2e-14
Hs16950601 [Z] KOG0613 Projectin/twitchin and related proteins 78 2e-14
CE27768 [R] KOG0586 Serine/threonine protein kinase 78 2e-14
CE26212 [T] KOG0582 Ste20-like serine/threonine protein kinase 78 2e-14
CE23838 [R] KOG0586 Serine/threonine protein kinase 78 2e-14
At5g04510 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 78 2e-14
At3g61960 [OUT] KOG0595 Serine/threonine-protein kinase involved... 78 2e-14
7292679 [G] KOG0599 Phosphorylase kinase gamma subunit 78 2e-14
YPL209c [D] KOG0580 Serine/threonine protein kinase 78 3e-14
HsM7657627 [D] KOG0575 Polo-like serine/threonine protein kinase 78 3e-14
Hs4759178 [D] KOG0580 Serine/threonine protein kinase 78 3e-14
At4g14580 [T] KOG0583 Serine/threonine protein kinase 78 3e-14
At3g06030 [T] KOG0198 MEKK and related serine/threonine protein ... 78 3e-14
SPCC1322.08 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 77 4e-14
Hs9966875 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 77 4e-14
Hs13899225 [R] KOG0586 Serine/threonine protein kinase 77 4e-14
SPCC63.08c [OUT] KOG0595 Serine/threonine-protein kinase involve... 77 6e-14
SPCC1919.01 [T] KOG0583 Serine/threonine protein kinase 77 6e-14
Hs4758194 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 77 6e-14
CE09360 [Z] KOG0613 Projectin/twitchin and related proteins 77 6e-14
At5g39440 [T] KOG0583 Serine/threonine protein kinase 77 6e-14
7290313 [T] KOG0193 Serine/threonine protein kinase RAF 77 6e-14
YMR001c [D] KOG0575 Polo-like serine/threonine protein kinase 77 7e-14
At5g24430 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 77 7e-14
At2g17290 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 76 9e-14
7299438 [R] KOG0586 Serine/threonine protein kinase 76 9e-14
Hs21361433 [D] KOG0575 Polo-like serine/threonine protein kinase 76 1e-13
CE20167 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD a... 76 1e-13
At4g35310 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 76 1e-13
YPL141c [T] KOG0583 Serine/threonine protein kinase 75 2e-13
YNR047w [R] KOG0610 Putative serine/threonine protein kinase 75 2e-13
Hs4502553 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 75 2e-13
Hs14770402 [R] KOG0586 Serine/threonine protein kinase 75 2e-13
At4g24100 [T] KOG0582 Ste20-like serine/threonine protein kinase 75 2e-13
7294217 [D] KOG0588 Serine/threonine protein kinase 75 2e-13
CE21025 [D] KOG0580 Serine/threonine protein kinase 75 2e-13
CE00847 [T] KOG0583 Serine/threonine protein kinase 75 2e-13
At5g66210 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 75 2e-13
At3g10540 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 75 2e-13
SPCC18B5.11c [D] KOG0615 Serine/threonine protein kinase Chk2 an... 75 3e-13
CE24516 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 75 3e-13
CE16081 [T] KOG0583 Serine/threonine protein kinase 75 3e-13
YPL153c [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 74 4e-13
YKL101w [D] KOG0588 Serine/threonine protein kinase 74 4e-13
7299793 [T] KOG0583 Serine/threonine protein kinase 74 4e-13
7299536 [D] KOG0580 Serine/threonine protein kinase 74 4e-13
SPAC9G1.02 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 an... 74 5e-13
Hs18552621 [R] KOG0597 Serine-threonine protein kinase FUSED 74 5e-13
Hs14196445 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 74 5e-13
CE27573 [T] KOG0198 MEKK and related serine/threonine protein ki... 74 5e-13
CE07737 [T] KOG0198 MEKK and related serine/threonine protein ki... 74 5e-13
At4g10730 [T] KOG0582 Ste20-like serine/threonine protein kinase 74 5e-13
SPCC74.03c [T] KOG0583 Serine/threonine protein kinase 74 6e-13
SPCC162.10 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 74 6e-13
SPBC1861.09 [R] KOG0610 Putative serine/threonine protein kinase 74 6e-13
SPACUNK12.02c [T] KOG0032 Ca2+/calmodulin-dependent protein kina... 74 6e-13
Hs4826878 [T] KOG0582 Ste20-like serine/threonine protein kinase 74 6e-13
Hs4507273 [D] KOG0580 Serine/threonine protein kinase 74 6e-13
Hs20479818 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 74 6e-13
At2g34180 [T] KOG0583 Serine/threonine protein kinase 74 6e-13
SPCC70.05c [D] KOG0590 Checkpoint kinase and related serine/thre... 73 8e-13
SPAC9G1.09 [T] KOG0201 Serine/threonine protein kinase 73 8e-13
Hs5803125 [T] KOG0583 Serine/threonine protein kinase 73 8e-13
Hs13649368 [T] KOG0583 Serine/threonine protein kinase 73 8e-13
CE02377 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 73 8e-13
7293666 [D] KOG0575 Polo-like serine/threonine protein kinase 73 8e-13
SPAC890.03 [T] KOG0583 Serine/threonine protein kinase 73 1e-12
SPAC57A10.02 [D] KOG0588 Serine/threonine protein kinase 73 1e-12
Hs4759050 [T] KOG0603 Ribosomal protein S6 kinase 73 1e-12
At1g63700 [T] KOG0198 MEKK and related serine/threonine protein ... 73 1e-12
At1g12680 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 73 1e-12
7296450 [D] KOG0575 Polo-like serine/threonine protein kinase 73 1e-12
SPBC1604.14c [T] KOG0578 p21-activated serine/threonine protein ... 72 1e-12
SPAC23C11.16 [D] KOG0575 Polo-like serine/threonine protein kinase 72 1e-12
Hs20149547 [T] KOG0603 Ribosomal protein S6 kinase 72 1e-12
YPL150w [T] KOG0583 Serine/threonine protein kinase 72 2e-12
YOR233w [T] KOG0583 Serine/threonine protein kinase 72 2e-12
SPCC576.15c [T] KOG0592 3-phosphoinositide-dependent protein kin... 72 2e-12
Hs14776113 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 72 2e-12
YCR091w [R] KOG0610 Putative serine/threonine protein kinase 72 2e-12
Hs7019543 [T] KOG0582 Ste20-like serine/threonine protein kinase 72 2e-12
Hs14754789 [OUT] KOG0595 Serine/threonine-protein kinase involve... 72 2e-12
At4g04700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 72 2e-12
YJL164c [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 71 3e-12
Hs7662388 [T] KOG0661 MAPK related serine/threonine protein kinase 71 3e-12
Hs7661974 [T] KOG0583 Serine/threonine protein kinase 71 3e-12
Hs4505695 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 71 3e-12
CE28218 [D] KOG0588 Serine/threonine protein kinase 71 3e-12
CE25585 [T] KOG0193 Serine/threonine protein kinase RAF 71 3e-12
At5g14720 [T] KOG0582 Ste20-like serine/threonine protein kinase 71 3e-12
Hs20545245 [D] KOG0588 Serine/threonine protein kinase 71 4e-12
At3g27560 [T] KOG0192 Tyrosine kinase specific for activated (GT... 71 4e-12
YKL166c [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 70 5e-12
YBR028c [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 70 5e-12
Hs14993776 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 70 5e-12
CE28674 [T] KOG0201 Serine/threonine protein kinase 70 5e-12
CE25046 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 70 5e-12
CE07510 [T] KOG0201 Serine/threonine protein kinase 70 5e-12
At2g46700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 70 5e-12
SPBC8D2.19 [T] KOG0661 MAPK related serine/threonine protein kinase 70 7e-12
Hs7705551 [T] KOG0661 MAPK related serine/threonine protein kinase 70 7e-12
Hs4506075 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD... 70 7e-12
CE03584 [T] KOG0607 MAP kinase-interacting kinase and related se... 70 7e-12
At5g40540 [T] KOG0192 Tyrosine kinase specific for activated (GT... 70 7e-12
7302570 [R] KOG0586 Serine/threonine protein kinase 70 7e-12
7295638 [T] KOG0603 Ribosomal protein S6 kinase 70 7e-12
7290147 [T] KOG0583 Serine/threonine protein kinase 70 7e-12
YOL045w [T] KOG1152 Signal transduction serine/threonine kinase ... 70 9e-12
YDL101c [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 70 9e-12
Hs7382496 [T] KOG0578 p21-activated serine/threonine protein kinase 70 9e-12
Hs10334852 [T] KOG0612 Rho-associated coiled-coil containing pro... 70 9e-12
CE28479 [T] KOG0583 Serine/threonine protein kinase 70 9e-12
CE11916 [T] KOG0612 Rho-associated coiled-coil containing protei... 70 9e-12
At1g67890 [T] KOG0192 Tyrosine kinase specific for activated (GT... 70 9e-12
7297080 [T] KOG0583 Serine/threonine protein kinase 70 9e-12
YAR019c [T] KOG0198 MEKK and related serine/threonine protein ki... 69 1e-11
Hs4506737 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 69 1e-11
Hs22057171 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 69 1e-11
ECU03g0980 [T] KOG0583 Serine/threonine protein kinase 69 1e-11
YDR490c [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 69 1e-11
YBR274w [D] KOG0590 Checkpoint kinase and related serine/threoni... 69 1e-11
Hs7705748 [T] KOG0192 Tyrosine kinase specific for activated (GT... 69 1e-11
Hs4885583 [T] KOG0612 Rho-associated coiled-coil containing prot... 69 1e-11
Hs16950619 [Z] KOG0613 Projectin/twitchin and related proteins 69 1e-11
Hs16950615 [Z] KOG0613 Projectin/twitchin and related proteins 69 1e-11
CE28061 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 69 1e-11
CE28060 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 69 1e-11
CE28059 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 69 1e-11
CE28058 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 69 1e-11
CE28057 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 69 1e-11
CE28056 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 69 1e-11
CE28055 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 69 1e-11
CE28054 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 69 1e-11
CE28053 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 69 1e-11
CE28051 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 69 1e-11
CE17284 [T] KOG0583 Serine/threonine protein kinase 69 1e-11
At3g04530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 69 1e-11
7291742_1 [T] KOG0612 Rho-associated coiled-coil containing prot... 69 1e-11
SPAC19E9.02 [D] KOG0591 NIMA (never in mitosis)-related G2-speci... 69 2e-11
HsM5454174 [T] KOG0201 Serine/threonine protein kinase 69 2e-11
Hs5032091 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 69 2e-11
Hs4505785 [G] KOG0599 Phosphorylase kinase gamma subunit 69 2e-11
Hs21361358 [T] KOG0201 Serine/threonine protein kinase 69 2e-11
Hs19923468 [T] KOG4236 Serine/threonine protein kinase PKC mu/PK... 69 2e-11
Hs16950617 [Z] KOG0613 Projectin/twitchin and related proteins 69 2e-11
ECU11g1500 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 69 2e-11
At5g50180 [T] KOG0192 Tyrosine kinase specific for activated (GT... 69 2e-11
At4g23650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 69 2e-11
At3g51850 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 69 2e-11
7298926 [T] KOG0578 p21-activated serine/threonine protein kinase 69 2e-11
YJL057c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 68 3e-11
YDR466w [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 68 3e-11
Hs4758192 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 68 3e-11
Hs20070158 [T] KOG0201 Serine/threonine protein kinase 68 3e-11
CE28251 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 68 3e-11
CE21615 [T] KOG0578 p21-activated serine/threonine protein kinase 68 3e-11
At5g66710 [T] KOG0192 Tyrosine kinase specific for activated (GT... 68 3e-11
At5g03730 [T] KOG0192 Tyrosine kinase specific for activated (GT... 68 3e-11
At5g01850 [T] KOG0192 Tyrosine kinase specific for activated (GT... 68 3e-11
At3g46930 [T] KOG0192 Tyrosine kinase specific for activated (GT... 68 3e-11
At3g17850 [TR] KOG0606 Microtubule-associated serine/threonine k... 68 3e-11
At1g53570 [T] KOG0198 MEKK and related serine/threonine protein ... 68 3e-11
7302511 [T] KOG0576 Mitogen-activated protein kinase kinase kina... 68 3e-11
7300106 [T] KOG0690 Serine/threonine protein kinase 68 3e-11
7297776 [D] KOG0580 Serine/threonine protein kinase 68 3e-11
7297578 [T] KOG0661 MAPK related serine/threonine protein kinase 68 3e-11
Hs22050308_2 [T] KOG0198 MEKK and related serine/threonine prote... 68 3e-11
YOR351c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 68 3e-11
Hs7657526 [T] KOG0603 Ribosomal protein S6 kinase 68 3e-11
Hs21361643 [T] KOG4717 Serine/threonine protein kinase 68 3e-11
Hs18596354 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 68 3e-11
CE12408 [T] KOG0661 MAPK related serine/threonine protein kinase 68 3e-11
At5g49470 [T] KOG0192 Tyrosine kinase specific for activated (GT... 68 3e-11
At4g14480 [T] KOG0582 Ste20-like serine/threonine protein kinase 68 3e-11
At4g08500 [T] KOG0198 MEKK and related serine/threonine protein ... 68 3e-11
At3g53930 [OUT] KOG0595 Serine/threonine-protein kinase involved... 68 3e-11
At3g06620 [T] KOG0192 Tyrosine kinase specific for activated (GT... 68 3e-11
At1g51660 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 68 3e-11
7304358 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 68 3e-11
7303211 [T] KOG4717 Serine/threonine protein kinase 68 3e-11
Hs6005922_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 68 3e-11
Hs5031689 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD... 67 4e-11
Hs4885489 [T] KOG0192 Tyrosine kinase specific for activated (GT... 67 4e-11
Hs4505601 [T] KOG0578 p21-activated serine/threonine protein kinase 67 4e-11
Hs11496279 [T] KOG0661 MAPK related serine/threonine protein kinase 67 4e-11
ECU01g1320 [T] KOG0612 Rho-associated coiled-coil containing pro... 67 4e-11
CE27410 [T] KOG0583 Serine/threonine protein kinase 67 4e-11
CE21879 [D] KOG0590 Checkpoint kinase and related serine/threoni... 67 4e-11
At4g04710 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 67 4e-11
7293249 [T] KOG0612 Rho-associated coiled-coil containing protei... 67 4e-11
HsM8923212 [T] KOG4717 Serine/threonine protein kinase 67 6e-11
Hs4503787 [T] KOG0197 Tyrosine kinases 67 6e-11
Hs4502803 [D] KOG0590 Checkpoint kinase and related serine/threo... 67 6e-11
CE27297 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 67 6e-11
7292656 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 67 6e-11
CE02602_1 [T] KOG0660 Mitogen-activated protein kinase 67 6e-11
At1g16270_2 [T] KOG0192 Tyrosine kinase specific for activated (... 67 6e-11
YOL100w [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 67 7e-11
YNL298w [T] KOG0578 p21-activated serine/threonine protein kinase 67 7e-11
Hs19923407 [D] KOG0591 NIMA (never in mitosis)-related G2-specif... 67 7e-11
SPBC337.04 [R] KOG0586 Serine/threonine protein kinase 66 1e-10
SPBC21.06c [T] KOG0198 MEKK and related serine/threonine protein... 66 1e-10
Hs7662210 [OUT] KOG0595 Serine/threonine-protein kinase involved... 66 1e-10
Hs19923570 [T] KOG0603 Ribosomal protein S6 kinase 66 1e-10
Hs17455844 [TR] KOG0606 Microtubule-associated serine/threonine ... 66 1e-10
CE18169 [T] KOG0603 Ribosomal protein S6 kinase 66 1e-10
CE13014 [T] KOG0603 Ribosomal protein S6 kinase 66 1e-10
CE02604 [T] KOG0695 Serine/threonine protein kinase 66 1e-10
At4g18710 [G] KOG0658 Glycogen synthase kinase-3 66 1e-10
7291778 [T] KOG0579 Ste20-like serine/threonine protein kinase 66 1e-10
Hs5902140_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 66 1e-10
YGL158w [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 66 1e-10
Hs4759044 [T] KOG0612 Rho-associated coiled-coil containing prot... 66 1e-10
Hs20536595 [T] KOG0612 Rho-associated coiled-coil containing pro... 66 1e-10
CE21086 [D] KOG0590 Checkpoint kinase and related serine/threoni... 66 1e-10
At5g66850 [T] KOG0198 MEKK and related serine/threonine protein ... 66 1e-10
At4g35780 [T] KOG0192 Tyrosine kinase specific for activated (GT... 66 1e-10
At3g21220 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 66 1e-10
At3g08730 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 66 1e-10
At3g08720 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 66 1e-10
7304283 [Z] KOG0613 Projectin/twitchin and related proteins 66 1e-10
7292249 [T] KOG0587 Traf2- and Nck-interacting kinase and relate... 66 1e-10
Hs20070247_2 [RT] KOG0598 Ribosomal protein S6 kinase and relate... 66 1e-10
At1g54960 [T] KOG0198 MEKK and related serine/threonine protein ... 65 2e-10
7293601 [T] KOG0577 Serine/threonine protein kinase 65 2e-10
YLR096w [T] KOG0583 Serine/threonine protein kinase 65 2e-10
Hs5453972 [T] KOG0694 Serine/threonine protein kinase 65 2e-10
Hs5453882 [G] KOG0599 Phosphorylase kinase gamma subunit 65 2e-10
Hs19923464 [T] KOG0577 Serine/threonine protein kinase 65 2e-10
CE28744 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 65 2e-10
CE05507 [T] KOG0603 Ribosomal protein S6 kinase 65 2e-10
At3g63260 [T] KOG0192 Tyrosine kinase specific for activated (GT... 65 2e-10
At3g06630 [T] KOG0192 Tyrosine kinase specific for activated (GT... 65 2e-10
YDR523c [T] KOG0201 Serine/threonine protein kinase 65 3e-10
SPAC644.06c [D] KOG0588 Serine/threonine protein kinase 65 3e-10
Hs22035600 [T] KOG0576 Mitogen-activated protein kinase kinase k... 65 3e-10
Hs20553830 [J] KOG1035 eIF-2alpha kinase GCN2 65 3e-10
Hs19424132 [D] KOG0591 NIMA (never in mitosis)-related G2-specif... 65 3e-10
CE15235 [R] KOG0589 Serine/threonine protein kinase 65 3e-10
At4g31170 [T] KOG0192 Tyrosine kinase specific for activated (GT... 65 3e-10
At2g34650 [R] KOG0610 Putative serine/threonine protein kinase 65 3e-10
7294566 [T] KOG0612 Rho-associated coiled-coil containing protei... 65 3e-10
Hs16357474_1 [T] KOG0612 Rho-associated coiled-coil containing p... 65 3e-10
At1g79570_2 [T] KOG0192 Tyrosine kinase specific for activated (... 65 3e-10
YCR073c [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and r... 64 4e-10
YAL017w [T] KOG1152 Signal transduction serine/threonine kinase ... 64 4e-10
Hs4885563 [T] KOG0694 Serine/threonine protein kinase 64 4e-10
Hs4505599 [T] KOG0578 p21-activated serine/threonine protein kinase 64 4e-10
Hs4505153 [T] KOG0198 MEKK and related serine/threonine protein ... 64 4e-10
Hs4504101 [T] KOG0986 G protein-coupled receptor kinase 64 4e-10
CE18366 [T] KOG0583 Serine/threonine protein kinase 64 4e-10
7295426 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 64 4e-10
At1g04700_2 [T] KOG0192 Tyrosine kinase specific for activated (... 64 4e-10
SPAC14C4.03 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 64 5e-10
HsM4759010 [T] KOG0576 Mitogen-activated protein kinase kinase k... 64 5e-10
Hs7706286 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase E... 64 5e-10
Hs5730055 [D] KOG0575 Polo-like serine/threonine protein kinase 64 5e-10
Hs5453976 [T] KOG0694 Serine/threonine protein kinase 64 5e-10
Hs20543401 [TR] KOG0606 Microtubule-associated serine/threonine ... 64 5e-10
Hs16418343 [T] KOG0583 Serine/threonine protein kinase 64 5e-10
Hs14149671 [TR] KOG0606 Microtubule-associated serine/threonine ... 64 5e-10
Hs14141724 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase ... 64 5e-10
CE26649 [D] KOG0575 Polo-like serine/threonine protein kinase 64 5e-10
CE20493 [TR] KOG0606 Microtubule-associated serine/threonine kin... 64 5e-10
7303860 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 64 5e-10
YPL203w [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 64 6e-10
SPAC4G8.05 [R] KOG0610 Putative serine/threonine protein kinase 64 6e-10
CE27670 [T] KOG0578 p21-activated serine/threonine protein kinase 64 6e-10
At4g13020 [T] KOG0661 MAPK related serine/threonine protein kinase 64 6e-10
At2g17700 [T] KOG0192 Tyrosine kinase specific for activated (GT... 64 6e-10
7301213 [R] KOG0589 Serine/threonine protein kinase 64 6e-10
7294265 [TR] KOG0606 Microtubule-associated serine/threonine kin... 64 6e-10
HsM5729922 [T] KOG0198 MEKK and related serine/threonine protein... 63 8e-10
Hs7706401 [T] KOG0577 Serine/threonine protein kinase 63 8e-10
Hs6382058 [T] KOG4278 Protein tyrosine kinase 63 8e-10
Hs5453978 [T] KOG0614 cGMP-dependent protein kinase 63 8e-10
Hs4885045 [T] KOG4278 Protein tyrosine kinase 63 8e-10
Hs4759208 [T] KOG0577 Serine/threonine protein kinase 63 8e-10
Hs4506539 [T] KOG0192 Tyrosine kinase specific for activated (GT... 63 8e-10
Hs4505831 [T] KOG0612 Rho-associated coiled-coil containing prot... 63 8e-10
Hs16507245 [T] KOG0583 Serine/threonine protein kinase 63 8e-10
Hs14042947 [T] KOG0583 Serine/threonine protein kinase 63 8e-10
ECU08g0230 [R] KOG0594 Protein kinase PCTAIRE and related kinases 63 8e-10
CE28760 [R] KOG0605 NDR and related serine/threonine kinases 63 8e-10
At3g24720 [T] KOG0192 Tyrosine kinase specific for activated (GT... 63 8e-10
At2g31010 [T] KOG0192 Tyrosine kinase specific for activated (GT... 63 8e-10
At1g69220 [T] KOG0576 Mitogen-activated protein kinase kinase ki... 63 8e-10
At2g35050_2 [T] KOG0192 Tyrosine kinase specific for activated (... 63 8e-10
Hs7706445 [T] KOG0664 Nemo-like MAPK-related serine/threonine pr... 63 1e-09
ECU05g1510 [TDK] KOG0668 Casein kinase II alpha subunit 63 1e-09
CE29453 [T] KOG0192 Tyrosine kinase specific for activated (GTP-... 63 1e-09
CE01554 [T] KOG0986 G protein-coupled receptor kinase 63 1e-09
CE01008 [T] KOG0583 Serine/threonine protein kinase 63 1e-09
At5g11850 [T] KOG0192 Tyrosine kinase specific for activated (GT... 63 1e-09
At3g50720 [T] KOG0192 Tyrosine kinase specific for activated (GT... 63 1e-09
At1g54510 [R] KOG0589 Serine/threonine protein kinase 63 1e-09
7301734 [T] KOG0694 Serine/threonine protein kinase 63 1e-09
7290841 [D] KOG0591 NIMA (never in mitosis)-related G2-specific ... 63 1e-09
Hs4505195 [T] KOG0192 Tyrosine kinase specific for activated (GT... 62 1e-09
Hs4502709 [R] KOG0594 Protein kinase PCTAIRE and related kinases 62 1e-09
Hs4502023 [T] KOG0690 Serine/threonine protein kinase 62 1e-09
Hs21735556 [T] KOG0198 MEKK and related serine/threonine protein... 62 1e-09
CE26076 [D] KOG0590 Checkpoint kinase and related serine/threoni... 62 1e-09
At5g50000 [T] KOG0192 Tyrosine kinase specific for activated (GT... 62 1e-09
YHR205w [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 62 2e-09
SPBC32C12.03c [T] KOG0583 Serine/threonine protein kinase 62 2e-09
Hs5031975 [T] KOG0578 p21-activated serine/threonine protein kinase 62 2e-09
Hs4885347 [T] KOG0986 G protein-coupled receptor kinase 62 2e-09
Hs20545357 [T] KOG0583 Serine/threonine protein kinase 62 2e-09
Hs14728804 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 62 2e-09
ECU07g0360 [D] KOG0580 Serine/threonine protein kinase 62 2e-09
CE24941 [T] KOG0983 Mitogen-activated protein kinase (MAPK) kina... 62 2e-09
CE18454 [T] KOG4717 Serine/threonine protein kinase 62 2e-09
At5g58950 [T] KOG0192 Tyrosine kinase specific for activated (GT... 62 2e-09
At2g30980 [G] KOG0658 Glycogen synthase kinase-3 62 2e-09
At2g23030 [T] KOG0583 Serine/threonine protein kinase 62 2e-09
7299507 [T] KOG0607 MAP kinase-interacting kinase and related se... 62 2e-09
Hs5453970 [T] KOG0694 Serine/threonine protein kinase 62 2e-09
Hs4885549 [T] KOG0690 Serine/threonine protein kinase 62 2e-09
Hs4507831 [OUT] KOG0595 Serine/threonine-protein kinase involved... 62 2e-09
Hs4506103 [J] KOG1033 eIF-2alpha kinase PEK/EIF2AK3 62 2e-09
Hs22068916 [T] KOG0696 Serine/threonine protein kinase 62 2e-09
Hs20127450 [T] KOG0696 Serine/threonine protein kinase 62 2e-09
Hs14735945 [T] KOG0694 Serine/threonine protein kinase 62 2e-09
Hs14249562 [TR] KOG0606 Microtubule-associated serine/threonine ... 62 2e-09
CE27166 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 62 2e-09
CE04603 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 62 2e-09
CE02074 [T] KOG0986 G protein-coupled receptor kinase 62 2e-09
At1g09000 [T] KOG0198 MEKK and related serine/threonine protein ... 62 2e-09
7298323 [D] KOG0590 Checkpoint kinase and related serine/threoni... 62 2e-09
At5g57610_2 [T] KOG0192 Tyrosine kinase specific for activated (... 62 2e-09
ECU11g0960 [D] KOG0600 Cdc2-related protein kinase 61 3e-09
CE12518 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 61 3e-09
At5g62310 [TR] KOG0606 Microtubule-associated serine/threonine k... 61 3e-09
At3g50730 [T] KOG0192 Tyrosine kinase specific for activated (GT... 61 3e-09
At1g06390 [G] KOG0658 Glycogen synthase kinase-3 61 3e-09
7297611 [T] KOG0614 cGMP-dependent protein kinase 61 3e-09
YHL007c [T] KOG0578 p21-activated serine/threonine protein kinase 61 4e-09
SPAC24B11.06c [T] KOG0660 Mitogen-activated protein kinase 61 4e-09
Hs4885349 [T] KOG0986 G protein-coupled receptor kinase 61 4e-09
Hs22042851 [T] KOG0986 G protein-coupled receptor kinase 61 4e-09
CE09689 [T] KOG0194 Protein tyrosine kinase 61 4e-09
At5g63610 [K] KOG0666 Cyclin C-dependent kinase CDK8 61 4e-09
At5g08160 [KIT] KOG2345 Serine/threonine protein kinase/TGF-beta... 61 4e-09
At3g59410 [J] KOG1035 eIF-2alpha kinase GCN2 61 4e-09
At3g06640 [T] KOG0192 Tyrosine kinase specific for activated (GT... 61 4e-09
At1g57870 [G] KOG0658 Glycogen synthase kinase-3 61 4e-09
At1g10940 [T] KOG0583 Serine/threonine protein kinase 61 4e-09
SPAC29A4.16 [D] KOG0590 Checkpoint kinase and related serine/thr... 60 5e-09
HsM4826916 [D] KOG0575 Polo-like serine/threonine protein kinase 60 5e-09
Hs9910476 [T] KOG0578 p21-activated serine/threonine protein kinase 60 5e-09
Hs8923754 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 60 5e-09
Hs4885061 [T] KOG0690 Serine/threonine protein kinase 60 5e-09
Hs14589909 [T] KOG0576 Mitogen-activated protein kinase kinase k... 60 5e-09
CE04586 [T] KOG1989 ARK protein kinase family 60 5e-09
At3g61160 [G] KOG0658 Glycogen synthase kinase-3 60 5e-09
7301971 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 60 5e-09
7295173 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 60 5e-09
SPBC4C3.11 [T] KOG0592 3-phosphoinositide-dependent protein kina... 60 7e-09
Hs4506067 [T] KOG0696 Serine/threonine protein kinase 60 7e-09
Hs20127541 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 60 7e-09
Hs10835242 [T] KOG0614 cGMP-dependent protein kinase 60 7e-09
ECU07g0520 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 60 7e-09
CE05274 [T] KOG0690 Serine/threonine protein kinase 60 7e-09
CE04172 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 60 7e-09
At5g14640 [G] KOG0658 Glycogen synthase kinase-3 60 7e-09
7303111 [T] KOG0695 Serine/threonine protein kinase 60 7e-09
7300149 [T] KOG0578 p21-activated serine/threonine protein kinase 60 7e-09
At1g49180_1 [OUT] KOG0595 Serine/threonine-protein kinase involv... 60 7e-09
YDR283c [J] KOG1035 eIF-2alpha kinase GCN2 60 9e-09
YDR122w [T] KOG0583 Serine/threonine protein kinase 60 9e-09
SPBC4F6.06 [T] KOG0583 Serine/threonine protein kinase 60 9e-09
SPBC1D7.05c [T] KOG0198 MEKK and related serine/threonine protei... 60 9e-09
SPAC2C4.14c [T] KOG0201 Serine/threonine protein kinase 60 9e-09
Hs8923539 [R] KOG0597 Serine-threonine protein kinase FUSED 60 9e-09
>YKL048c [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kinase beta
and related serine/threonine protein kinases
Length = 640
Score = 270 bits (689), Expect = 4e-72
Identities = 139/332 (41%), Positives = 208/332 (61%), Gaps = 18/332 (5%)
Query: 67 QKFVNQYRIGERLGCGQFGTVYKGH--TTGKVVAIKQIYKKPMNSP-FSMSLIMKTMKRY 123
+K +NQY +G G GQFG V K + T GKVVA+K I KKP N+ +S++ +M+ ++ +
Sbjct: 82 KKTINQYTLGVSAGSGQFGYVRKAYSSTLGKVVAVKIIPKKPWNAQQYSVNQVMRQIQLW 141
Query: 124 ES-------ISGDVLIMEMNVSKIRWECFVTSKL-NHPNVIQLLECLDSPYSDQIWLIQP 175
+S +SG+ + MN+ K RWE F S+L N+ ++++L+ECLDSP+S+ IW++
Sbjct: 142 KSKGKITTNMSGNEAMRLMNIEKCRWEIFAASRLRNNVHIVRLIECLDSPFSESIWIVTN 201
Query: 176 LAVLGELQWSRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDL 235
LGELQW R+ D++ QWK SV FA K+L D++ GL+YL QG IHRD+
Sbjct: 202 WCSLGELQWKRDDDEDILPQWKKIVISNC-SVSTFAKKILEDMTKGLEYLHSQGCIHRDI 260
Query: 236 KPQNILLDPVYHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCN 295
KP NILLD ++SDFG + P LPF D +D F++ELNKIVGTP F APELC+
Sbjct: 261 KPSNILLDEEEKVAKLSDFGSCIFTPQSLPFSDANFEDCFQRELNKIVGTPAFIAPELCH 320
Query: 296 FAEGSAHASNEQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSS 355
+ FK+D+WSLG+T+Y +LYN LPF+GE EF+TY+ I L ++ ++
Sbjct: 321 LGNSKRDFVTD-GFKLDIWSLGVTLYCLLYNELPFFGENEFETYHKIIEVSLSSKINGNT 379
Query: 356 NIYGWIHEYVVNRMLSKNTASRPTTSNILRTL 387
+++ V+ R+L K+ R + ++++ L
Sbjct: 380 -----LNDLVIKRLLEKDVTLRISIQDLVKVL 406
>YGL179c [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kinase beta
and related serine/threonine protein kinases
Length = 560
Score = 124 bits (312), Expect = 2e-28
Identities = 85/285 (29%), Positives = 146/285 (50%), Gaps = 37/285 (12%)
Query: 67 QKFVNQYRIGERLGCGQFGTVYKGHT--TGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYE 124
++ +N + I LG GQ+G V TG +VAIK + R+E
Sbjct: 44 RQILNNFEILATLGNGQYGKVKLARDLGTGALVAIK------------------ILNRFE 85
Query: 125 SISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQW 184
SG L +++ ++ E V + +H NV++L E L+ P S +++L+ G ++W
Sbjct: 86 KRSGYSLQLKVENPRVNQEIEVMKRCHHENVVELYEILNDPESTKVYLVLEYCSRGPVKW 145
Query: 185 SRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDP 244
E+K ++ S Q KV+ D+ +GL+YL QGI HRD+KP N+L+
Sbjct: 146 CPENKMEIKAVGPSILTFQQSR------KVVLDVVSGLEYLHSQGITHRDIKPSNLLISS 199
Query: 245 VYHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKEL-NKIVGTPLFTAPELCNFAEGSAHA 303
+++ISDFG ++ + +Q E+ L ++ +GTP F APELC+ + + +
Sbjct: 200 -NGTVKISDFGVAMSTAT----GSTNIQSSHEQLLKSRALGTPAFFAPELCSTEKEYSCS 254
Query: 304 SNEQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLK 348
S ID+WSLG+T+Y +L+ LPF + + ++ I ++ L+
Sbjct: 255 S-----AIDIWSLGVTIYCLLFGKLPFNANSGLELFDSIINKPLE 294
>SPCC297.03 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kinase beta
and related serine/threonine protein kinases
Length = 652
Score = 122 bits (305), Expect = 1e-27
Identities = 101/333 (30%), Positives = 158/333 (47%), Gaps = 59/333 (17%)
Query: 27 FQIIDEQQKKL-ELGVISKTKIIERYVXXXXXXXXXQEEHAQKFVNQYRIGERLGCGQFG 85
FQ Q K+L E G + +TK I + +K++N Y I + LG G G
Sbjct: 97 FQEAQRQWKRLQEWGEVKETKKIRKRFDRFS---------GRKYINHYEIIKELGRGMHG 147
Query: 86 TVYKGH--TTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISGDVLIMEMNVSKIRWE 143
V G T +++AIK +I KT +R + + + K+R E
Sbjct: 148 KVKLGRDTVTRELLAIK--------------IIPKTERRPKLGRANASSQK---EKVRRE 190
Query: 144 CFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSR-ESKFDLIEQWKSFYRG 202
+ K HPNV++L E +D P S +++L+ GE+ W+ +S I + + ++R
Sbjct: 191 IAILKKCVHPNVVRLREVIDDPSSTKVYLVLEYMSGGEVPWTDCDSPVLSISEARQYFR- 249
Query: 203 QLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYHSLRISDFGCSLIVPS 262
D+ GL+YL QGIIHRD+KP N+LL+ + ++ISDFG S I
Sbjct: 250 --------------DVVLGLEYLHYQGIIHRDIKPANLLLNS-SNCVKISDFGVSYIA-- 292
Query: 263 KLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQPFKIDVWSLGITVYA 322
+ L + + EL K VGTP F APELC + IDVW+LG+T++
Sbjct: 293 -----NAGLNEDNDVELAKTVGTPAFFAPELCWTDLDRPRPKISE--AIDVWALGVTLFC 345
Query: 323 ILYNVLPFWGETEFDTYNLICHRQLK----PDV 351
+L+ PF E++ ++ I + +L PD+
Sbjct: 346 LLFGRCPFNASMEYELFDKIVNERLNIPSTPDI 378
>YER129w [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kinase beta
and related serine/threonine protein kinases
Length = 1142
Score = 119 bits (298), Expect = 1e-26
Identities = 94/295 (31%), Positives = 148/295 (49%), Gaps = 37/295 (12%)
Query: 67 QKFVNQYRIGERLGCGQFGTVYKGHT--TGKVVAIKQI--YKKPMNSPFSMSLIMKTMKR 122
+K +N Y I + LG GQ G V + ++VAIK + ++K F+ +K+ K
Sbjct: 127 RKVLNTYEIIKELGHGQHGKVKLARDILSKQLVAIKIVDRHEKKQRKFFTF---IKSSKI 183
Query: 123 YESISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGEL 182
E+ KI+ E + K +H +V+QL+E LD S +I+L+ GE+
Sbjct: 184 SEN------------DKIKREIAIMKKCHHKHVVQLIEVLDDLKSRKIYLVLEYCSRGEV 231
Query: 183 QWSRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILL 242
+W + + S L S +E ++L + GL+YL QGIIHRD+KP N+L+
Sbjct: 232 KWCPPDCMESDAKGPS-----LLSFQETR-EILRGVVLGLEYLHYQGIIHRDIKPANLLI 285
Query: 243 DPVYHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELC-------- 294
+++ISDFG SL S + L E EL K VGTP F APE+C
Sbjct: 286 SGD-GTVKISDFGVSLAASSTNSSDSS--ESLDELELAKTVGTPAFFAPEMCLGEDAFTR 342
Query: 295 -NFAEGSAHASNEQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLK 348
N + + + F ID+W++G+T+Y +L+ +LPF+ + E + I + LK
Sbjct: 343 YNLTKENLFRGSCISFMIDIWAVGVTLYCLLFGMLPFFSDFELKLFEKIVNDPLK 397
>At5g60550 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kinase beta
and related serine/threonine protein kinases
Length = 407
Score = 105 bits (261), Expect = 2e-22
Identities = 94/323 (29%), Positives = 147/323 (45%), Gaps = 58/323 (17%)
Query: 62 QEEHAQKFVNQYRIGERLGCGQFGTV--YKGHTTGKVVAIKQIYKKPMNSPFSMSLIMKT 119
++E+ K +N+Y ++G G +G V Y+ G+ AIK +K L+
Sbjct: 98 EDENGDKTINEYVRVCKIGSGSYGKVVLYRSTLDGQYYAIKAFHKS--------HLLRLR 149
Query: 120 MKRYESISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVL 179
+ E+ DVL E+ + KI L HPN++ L+E +D P +D +++
Sbjct: 150 VAPSETAMSDVL-REVMIMKI---------LEHPNIVNLIEVIDDPETDHFYMVLEYV-- 197
Query: 180 GELQWSRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQN 239
+ +W + S G L E+ A K L DI GL YL +IH D+KP N
Sbjct: 198 -DGKWVYDG---------SGPPGALG--EKTARKYLRDIVTGLMYLHAHDVIHGDIKPDN 245
Query: 240 ILLDPVYHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEG 299
+L+ +++I DF S + FKD + +L + GTP+FTAPE C
Sbjct: 246 LLVTS-SGTVKIGDFSVSQV------FKDD------DDQLRRSPGTPVFTAPECCLGITY 292
Query: 300 SAHASNEQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQL-KPDVHN---SS 355
S A+ D W++G+T+Y ++ PF +T DTY+ I + L PD N
Sbjct: 293 SGRAA-------DTWAVGVTLYCMILGQYPFLADTLQDTYDKIVNNPLIIPDGLNPLLRD 345
Query: 356 NIYGWIHEYVVNRMLSKNTASRP 378
I G + + RM KN + P
Sbjct: 346 LIEGLLCKDPSQRMTLKNVSEHP 368
>CE01146 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kinase beta
and related serine/threonine protein kinases
Length = 357
Score = 103 bits (256), Expect = 7e-22
Identities = 88/313 (28%), Positives = 143/313 (45%), Gaps = 45/313 (14%)
Query: 70 VNQYRIGERLGCGQFGTVYKGHTTG--KVVAIKQIYKKPMNSPFSMSLIMKTMKRYESIS 127
+NQYR+ E +G G +G V + + A+K + K + F+ + E+ +
Sbjct: 18 LNQYRLMEEIGQGSYGIVKLAYNEEDKNLYALKVLDKMKLLKNFACFRQPPPRRNKENAA 77
Query: 128 GDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGE-LQWSR 186
VL + + ++ E + KL+HPNV++L+E LD P + ++++ G L+
Sbjct: 78 PSVLRNPLQL--VQKEIAILKKLSHPNVVKLVEVLDDPNDNYLYMVFEFVEKGSILEIPT 135
Query: 187 ESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVY 246
+ D W S++R D GL+YL Q I+HRD+KP N+LL +
Sbjct: 136 DKPLDEDTAW-SYFR---------------DTLCGLEYLHYQKIVHRDIKPSNLLLSDI- 178
Query: 247 HSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNE 306
++I+DFG S F G GTP F APE EG+ H +
Sbjct: 179 GQVKIADFGVSCEFEGIDAFLSG------------TAGTPAFMAPEA--LTEGANHFYSG 224
Query: 307 QPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLK--PDVHNSSNIYGWIHEY 364
+ D+WSLGIT+YA + +PF D Y + H+++K P V + I +
Sbjct: 225 R--AQDIWSLGITLYAFVIGTVPF-----VDNYIIALHKKIKNDPIVFPEAPILSEALQD 277
Query: 365 VVNRMLSKNTASR 377
++ ML K+ R
Sbjct: 278 IILGMLKKDPGHR 290
>At3g45240 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kinase beta
and related serine/threonine protein kinases
Length = 382
Score = 99.4 bits (246), Expect = 1e-20
Identities = 79/288 (27%), Positives = 127/288 (43%), Gaps = 57/288 (19%)
Query: 62 QEEHAQKFVNQYRIGERLGCGQFGTV--YKGHTTGKVVAIKQIYKKPMNSPFSMSLIMKT 119
++E K +N++ ++G G +G V Y+ K AIK +K ++
Sbjct: 86 EDEDGNKTINEFVRERKIGSGSYGKVVLYRSTVDDKHYAIKAFHKSHLSR--------LR 137
Query: 120 MKRYESISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVL 179
+ E+ GDVL E + L HPN++ L+E +D P D +++
Sbjct: 138 VAPSETAMGDVLR----------EVMIMKTLEHPNIVNLIEVIDDPEFDDFYMVLEYV-- 185
Query: 180 GELQWSRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQN 239
+ +W+ + S G L + A K L D+ GL YL +IH D+KP N
Sbjct: 186 -DGKWAYDD---------SGPPGALGEIT--ARKYLRDVVAGLMYLHAHNVIHGDIKPDN 233
Query: 240 ILLDPVYHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEG 299
+L+ ++I DF S QD + +L + GTP+FTAPE C
Sbjct: 234 LLVTSTGR-VKIGDFSVS--------------QD-DDDQLRRSPGTPVFTAPECCLGITY 277
Query: 300 SAHASNEQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQL 347
S ++ D W++G+T+Y ++ PF G+T DTY+ I H L
Sbjct: 278 SGRSA-------DTWAVGVTLYCMILGQYPFLGDTLQDTYDKIVHNPL 318
>Hs14150045 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kinase beta
and related serine/threonine protein kinases
Length = 505
Score = 97.1 bits (240), Expect = 5e-20
Identities = 88/315 (27%), Positives = 141/315 (43%), Gaps = 49/315 (15%)
Query: 70 VNQYRIGERLGCGQFGTVYKGHTTG--KVVAIKQIYKKPMNSPFSMSLIMKTMKRYESIS 127
+NQY++ +G G +G V + + A+K + KK + + + ++
Sbjct: 125 LNQYKLQSEIGKGAYGVVRLAYNESEDRHYAMKVLSKKKLLKQYGFPR-RPPPRGSQAAQ 183
Query: 128 GDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRE 187
G + + ++ E + KL+H NV++L+E LD P D ++L+ L G + E
Sbjct: 184 GGPAKQLLPLERVYQEIAILKKLDHVNVVKLIEVLDDPAEDNLYLVFDLLRKGPVM---E 240
Query: 188 SKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYH 247
D K F EE A L D+ GL+YL Q I+HRD+KP N+LL H
Sbjct: 241 VPCD-----KPFS-------EEQARLYLRDVILGLEYLHCQKIVHRDIKPSNLLLGDDGH 288
Query: 248 SLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQ 307
++I+DFG S + +L+ GTP F APE A + + Q
Sbjct: 289 -VKIADFGVSNQFEGN------------DAQLSSTAGTPAFMAPE--------AISDSGQ 327
Query: 308 PFK---IDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLK--PDVHNSSNIYGWIH 362
F +DVW+ G+T+Y +Y PF D + L HR++K P V
Sbjct: 328 SFSGKALDVWATGVTLYCFVYGKCPF-----IDDFILALHRKIKNEPVVFPEEPEISEEL 382
Query: 363 EYVVNRMLSKNTASR 377
+ ++ +ML KN +R
Sbjct: 383 KDLILKMLDKNPETR 397
>At2g25090 [T] KOG0583 Serine/threonine protein kinase
Length = 469
Score = 95.5 bits (236), Expect = 1e-19
Identities = 86/276 (31%), Positives = 127/276 (45%), Gaps = 56/276 (20%)
Query: 71 NQYRIGERLGCGQFGTVYKGH--TTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISG 128
++Y IG LG G F VY G +TG VAIK I K + K E I
Sbjct: 13 DKYNIGRLLGTGNFAKVYHGTEISTGDDVAIKVIKKDH---------VFKRRGMMEQIER 63
Query: 129 DVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRES 188
++ +M + L HPNV++L E + + +I+ + GEL
Sbjct: 64 EIAVMRL--------------LRHPNVVELREVMAT--KKKIFFVMEYVNGGEL------ 101
Query: 189 KFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYHS 248
F++I++ G+L E+ A K + + + + +G+ HRD+KP+N+LLD
Sbjct: 102 -FEMIDR-----DGKLP--EDLARKYFQQLISAVDFCHSRGVFHRDIKPENLLLDG-EGD 152
Query: 249 LRISDFGCS-LIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPE-LCNFAEGSAHASNE 306
L+++DFG S L++P L + G DL L+ GTP + APE L N A A
Sbjct: 153 LKVTDFGLSALMMPEGLGGRRGSSDDL----LHTRCGTPAYVAPEVLRNKGYDGAMA--- 205
Query: 307 QPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLI 342
D+WS GI +YA+L LPF E Y I
Sbjct: 206 -----DIWSCGIVLYALLAGFLPFIDENVMTLYTKI 236
>Hs17933758 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kinase beta
and related serine/threonine protein kinases
Length = 588
Score = 94.7 bits (234), Expect = 3e-19
Identities = 86/325 (26%), Positives = 141/325 (42%), Gaps = 69/325 (21%)
Query: 70 VNQYRIGERLGCGQFGTVYKGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTM--------- 120
+NQY + + +G G +G V K Y + N+ ++M ++ K
Sbjct: 162 LNQYTLKDEIGKGSYGVV------------KLAYNENDNTYYAMKVLSKKKLIRQAGFPR 209
Query: 121 ----KRYESISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPL 176
+ G + + ++ E + KL+HPNV++L+E LD P D ++++ L
Sbjct: 210 RPPPRGTRPAPGGCIQPRGPIEQVYQEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFEL 269
Query: 177 AVLGELQWSRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLK 236
G + K L E FY D+ G++YL Q IIHRD+K
Sbjct: 270 VNQGPVMEVPTLK-PLSEDQARFY--------------FQDLIKGIEYLHYQKIIHRDIK 314
Query: 237 PQNILLDPVYHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNF 296
P N+L+ H ++I+DFG S FK + L+ VGTP F APE +
Sbjct: 315 PSNLLVGEDGH-IKIADFGVS------NEFKGS------DALLSNTVGTPAFMAPE--SL 359
Query: 297 AEGSAHASNEQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQL----KPDVH 352
+E S + +DVW++G+T+Y ++ PF E ++ I + L +PD+
Sbjct: 360 SETRKIFSGK---ALDVWAMGVTLYCFVFGQCPFMDERIMCLHSKIKSQALEFPDQPDIA 416
Query: 353 NSSNIYGWIHEYVVNRMLSKNTASR 377
+ ++ RML KN SR
Sbjct: 417 EDL-------KDLITRMLDKNPESR 434
>7293496 [R] KOG0597 Serine-threonine protein kinase FUSED
Length = 805
Score = 94.4 bits (233), Expect = 3e-19
Identities = 81/283 (28%), Positives = 123/283 (42%), Gaps = 69/283 (24%)
Query: 70 VNQYRIGERLGCGQFGTVYKG--HTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESIS 127
+N+Y + +G G FG VYK KVVAIK I K+ +
Sbjct: 1 MNRYAVSSMVGQGSFGCVYKATRKDDSKVVAIKVISKRGRATK----------------- 43
Query: 128 GDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRE 187
+ +R EC + ++L HP+VI+++E +S ++++ A++
Sbjct: 44 --------ELKNLRRECDIQARLKHPHVIEMIESFES--KTDLFVVTEFALMD------- 86
Query: 188 SKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYH 247
+ ++ S Y G + EE A +V G + + L YL I+HRDLKPQN+LLD H
Sbjct: 87 -----LHRYLS-YNGAMG--EEPARRVTGHLVSALYYLHSNRILHRDLKPQNVLLDKNMH 138
Query: 248 SLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQ 307
+ ++ DFG + R L L I GTPL+ APEL EQ
Sbjct: 139 A-KLCDFGLA------------RNMTLGTHVLTSIKGTPLYMAPELL----------AEQ 175
Query: 308 PF--KIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLK 348
P+ D+WSLG Y + PF + +I H +K
Sbjct: 176 PYDHHADMWSLGCIAYESMAGQPPFCASSILHLVKMIKHEDVK 218
>Hs7662170 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 661
Score = 94.0 bits (232), Expect = 4e-19
Identities = 82/286 (28%), Positives = 130/286 (44%), Gaps = 72/286 (25%)
Query: 62 QEEHAQKFVNQYRIGERLGCGQFGTVYKG--HTTGKVVAIKQIYKKPMNSPFSMSLIMKT 119
+ H ++Y + E LG G +G V + +G+VVAIK I K
Sbjct: 44 RHHHKHNLKHRYELQETLGKGTYGKVKRATERFSGRVVAIKSIRK--------------- 88
Query: 120 MKRYESISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVL 179
D + E ++ IR E + S LNHP++I + E ++ D+I +I A
Sbjct: 89 ---------DKIKDEQDMVHIRREIEIMSSLNHPHIISIYEVFEN--KDKIVIIMEYASK 137
Query: 180 GELQWSRESKFDLIE-QWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQ 238
GEL + L E + + F+R I + + Y G++HRDLK +
Sbjct: 138 GELYDYISERRRLSERETRHFFR---------------QIVSAVHYCHKNGVVHRDLKLE 182
Query: 239 NILLDPVYHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKE--LNKIVGTPLFTAPELCNF 296
NILLD +++I+DFG L +L++K+ L G+PL+ +PE+ N
Sbjct: 183 NILLDD-NCNIKIADFG---------------LSNLYQKDKFLQTFCGSPLYASPEIVN- 225
Query: 297 AEGSAHASNEQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLI 342
G + E +D W+LG+ +Y ++Y +PF G FD NLI
Sbjct: 226 --GRPYRGPE----VDSWALGVLLYTLVYGTMPFDG---FDHKNLI 262
>At2g38910 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 583
Score = 94.0 bits (232), Expect = 4e-19
Identities = 90/319 (28%), Positives = 139/319 (43%), Gaps = 72/319 (22%)
Query: 73 YRIGERLGCGQFGTVYK--GHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISGDV 130
Y +G +LG GQFGT + TGK A K I K+ + +P + + + ++ +SG
Sbjct: 134 YSVGRKLGQGQFGTTFLCVDKKTGKEFACKTIAKRKLTTPEDVEDVRREIQIMHHLSG-- 191
Query: 131 LIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESKF 190
HPNVIQ++ + + + ++ + GEL F
Sbjct: 192 ---------------------HPNVIQIVGAYEDAVA--VHVVMEICAGGEL-------F 221
Query: 191 DLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILL--DPVYHS 248
D I Q RG E+ A ++ I ++ G++HRDLKP+N L +
Sbjct: 222 DRIIQ-----RGHY--TEKKAAELARIIVGVIEACHSLGVMHRDLKPENFLFVSGDEEAA 274
Query: 249 LRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQP 308
L+ DFG S+ FK G + +VG+P + APE+ H S+E
Sbjct: 275 LKTIDFGLSVF------FKPG-------ETFTDVVGSPYYVAPEVLR-----KHYSHE-- 314
Query: 309 FKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIYGWIHEY---V 365
DVWS G+ +Y +L V PFW ETE + + LK D+ S + + E +
Sbjct: 315 --CDVWSAGVIIYILLSGVPPFWDETEQGIFEQV----LKGDLDFISEPWPSVSESAKDL 368
Query: 366 VNRMLSKNTASRPTTSNIL 384
V RML ++ R TT +L
Sbjct: 369 VRRMLIRDPKKRMTTHEVL 387
>At2g41860 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 530
Score = 92.0 bits (227), Expect = 2e-18
Identities = 83/278 (29%), Positives = 118/278 (41%), Gaps = 65/278 (23%)
Query: 62 QEEHAQKFVNQYRIGERLGCGQFGTVY--KGHTTGKVVAIKQIYKKPMNSPFSMSLIMKT 119
+E + +Y++G LG G+FG Y TG++ A K I KK + KT
Sbjct: 43 KEPTGHEIKQKYKLGRELGRGEFGVTYLCTEIETGEIFACKSILKKKL----------KT 92
Query: 120 MKRYESISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVL 179
E + +V IM HPN++ L E + + + L+ L
Sbjct: 93 SIDIEDVKREVEIMRQMPE-------------HPNIVTLKETYEDDKA--VHLVMELCEG 137
Query: 180 GELQWSRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQN 239
GEL FD I RG E A V+ I +Q G++HRDLKP+N
Sbjct: 138 GEL-------FDRIVA-----RGHY--TERAAASVIKTIIEVVQMCHKHGVMHRDLKPEN 183
Query: 240 ILLDPVYH--SLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFA 297
L SL+ DFG S+ FK G + N+IVG+P + APE+ +
Sbjct: 184 FLFANKKETASLKAIDFGLSVF------FKPG-------ERFNEIVGSPYYMAPEVLRRS 230
Query: 298 EGSAHASNEQPFKIDVWSLGITVYAILYNVLPFWGETE 335
G +ID+WS G+ +Y +L V PFW ETE
Sbjct: 231 YGQ---------EIDIWSAGVILYILLCGVPPFWAETE 259
>At5g01820 [T] KOG0583 Serine/threonine protein kinase
Length = 442
Score = 91.7 bits (226), Expect = 2e-18
Identities = 88/324 (27%), Positives = 136/324 (41%), Gaps = 66/324 (20%)
Query: 63 EEHAQKFVNQYRIGERLGCGQFGTVYKGHTT--GKVVAIKQIYKKPMNSPFSMSLIMKTM 120
E + +Y +G+ +GCG F VY G +T G+ VAIK + K+ +
Sbjct: 12 ENRRGQLFGKYEVGKLVGCGAFAKVYHGRSTATGQSVAIKVVSKQRLQKG---------- 61
Query: 121 KRYESISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLG 180
++G+ I+ E + +L HP++++L E L + +I+ + A G
Sbjct: 62 ----GLNGN----------IQREIAIMHRLRHPSIVRLFEVLAT--KSKIFFVMEFAKGG 105
Query: 181 ELQWSRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNI 240
EL +++ SK E Y QL S + Y +GI HRDLKP+N+
Sbjct: 106 EL-FAKVSKGRFCEDLSRRYFQQLISA--------------VGYCHSRGIFHRDLKPENL 150
Query: 241 LLDPVYHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGS 300
LLD L+ISDFG S + P DG L L GTP + APE+
Sbjct: 151 LLDEKL-DLKISDFGLSALTDQIRP--DGLLHTL--------CGTPAYVAPEV------- 192
Query: 301 AHASNEQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIYGW 360
KID+WS GI ++ + LPF Y I + + S ++
Sbjct: 193 LAKKGYDGAKIDIWSCGIILFVLNAGYLPFNDHNLMVMYRKIYKGEFRIPKWTSPDL--- 249
Query: 361 IHEYVVNRMLSKNTASRPTTSNIL 384
++ R+L N +R T I+
Sbjct: 250 --RRLLTRLLDTNPQTRITIEEII 271
>Hs4557511 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 454
Score = 90.9 bits (224), Expect = 4e-18
Identities = 92/319 (28%), Positives = 138/319 (42%), Gaps = 64/319 (20%)
Query: 71 NQYRIGERLGCGQFGTVYKGHT--TGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISG 128
+ Y +GE LG GQF V K TGK A K I K+ ++S +S
Sbjct: 11 DHYEMGEELGSGQFAIVRKCRQKGTGKEYAAKFIKKRRLSSS------------RRGVSR 58
Query: 129 DVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRES 188
+ + E+N+ + ++ HPN+I L + ++ + LI L GEL
Sbjct: 59 EEIEREVNILR---------EIRHPNIITLHDIFEN--KTDVVLILELVSGGEL------ 101
Query: 189 KFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNI-LLDPVYH 247
FD + + +S E+ A + L I +G+ YL + I H DLKP+NI LLD
Sbjct: 102 -FDFLAEKESL-------TEDEATQFLKQILDGVHYLHSKRIAHFDLKPENIMLLDKNVP 153
Query: 248 SLRIS--DFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASN 305
+ RI DFG + + + FK+ I GTP F APE+ N+ A
Sbjct: 154 NPRIKLIDFGIAHKIEAGNEFKN-------------IFGTPEFVAPEIVNYEPLGLEA-- 198
Query: 306 EQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIYGWIHEYV 365
D+WS+G+ Y +L PF GET+ +T I D SN ++
Sbjct: 199 ------DMWSIGVITYILLSGASPFLGETKQETLTNISAVNYDFDEEYFSNTSELAKDF- 251
Query: 366 VNRMLSKNTASRPTTSNIL 384
+ R+L K+ R T + L
Sbjct: 252 IRRLLVKDPKRRMTIAQSL 270
>At2g30360 [T] KOG0583 Serine/threonine protein kinase
Length = 435
Score = 90.9 bits (224), Expect = 4e-18
Identities = 83/322 (25%), Positives = 143/322 (43%), Gaps = 76/322 (23%)
Query: 72 QYRIGERLGCGQFGTVY--KGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISGD 129
+Y +G+ LGCG F V+ + TG+ VA+K + KK + + +++
Sbjct: 20 KYELGKLLGCGAFAKVFHARDRRTGQSVAVKILNKKKLLTNPALA--------------- 64
Query: 130 VLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESK 189
+ I+ E + +L+HPN+++L E + + +I+ GEL
Sbjct: 65 --------NNIKREISIMRRLSHPNIVKLHEVMAT--KSKIFFAMEFVKGGEL------- 107
Query: 190 FDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYHSL 249
F+ I + G+L E+ + + + + + Y +G+ HRDLKP+N+L+D +L
Sbjct: 108 FNKISK-----HGRLS--EDLSRRYFQQLISAVGYCHARGVYHRDLKPENLLIDE-NGNL 159
Query: 250 RISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQPF 309
++SDFG S + P DG L L GTP + APE+ + +
Sbjct: 160 KVSDFGLSALTDQIRP--DGLLHTL--------CGTPAYVAPEILS-------KKGYEGA 202
Query: 310 KIDVWSLGITVYAILYNVLPFWGETEFDTYNLICH------RQLKPDVHNSSNIYGWIHE 363
K+DVWS GI ++ ++ LPF + Y I R + PD+ +
Sbjct: 203 KVDVWSCGIVLFVLVAGYLPFNDPNVMNMYKKIYKGEYRFPRWMSPDL-----------K 251
Query: 364 YVVNRMLSKNTASRPTTSNILR 385
V+R+L N +R T IL+
Sbjct: 252 RFVSRLLDINPETRITIDEILK 273
>At1g12580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 522
Score = 90.9 bits (224), Expect = 4e-18
Identities = 85/320 (26%), Positives = 145/320 (44%), Gaps = 70/320 (21%)
Query: 71 NQYRIGERLGCGQFGT--VYKGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISG 128
++Y +GE+LG GQFG V TG+ +A K SIS
Sbjct: 42 DRYVLGEQLGWGQFGVIRVCSDKLTGERLACK------------------------SISK 77
Query: 129 DVLIMEMNVSKIRWECFVTSKL-NHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRE 187
D L+ + ++ I+ E + +KL HPNV+ L + D + L+ L GEL
Sbjct: 78 DRLVTQDDMKSIKLEIAIMAKLAGHPNVVNLKAVYEE--KDSVHLVMELCAGGEL----- 130
Query: 188 SKFDLIEQWKSFYRGQLDSVEEFAVKVL-GDISNGLQYLQGQGIIHRDLKPQNILLDPVY 246
F +E++ + E +VL + +++ GI+HRDLKP+NIL+ +
Sbjct: 131 --FHKLEKYGRY--------SEVRARVLFKHLMQVVKFCHDSGIVHRDLKPENILMATMS 180
Query: 247 HS--LRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHAS 304
S ++++DFG + + K G ++L+ VG+P + APE+ A G A+
Sbjct: 181 SSSPIKLADFGLATYI------KPG-------EKLSGTVGSPFYIAPEV--LAGGYNQAA 225
Query: 305 NEQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIYGWIHEY 364
DVWS G+ +Y +L PFWG+T+ ++ + L+ NI + +
Sbjct: 226 -------DVWSAGVILYILLSGAPPFWGKTKSKIFDAVRAADLRFSAEPWDNITSYAKD- 277
Query: 365 VVNRMLSKNTASRPTTSNIL 384
++ ML + + R + +L
Sbjct: 278 LIRGMLCVDPSQRLSADEVL 297
>Hs22043888 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 765
Score = 90.1 bits (222), Expect = 6e-18
Identities = 86/330 (26%), Positives = 147/330 (44%), Gaps = 71/330 (21%)
Query: 70 VNQYRIGERLGCGQFGTVYK--GHTTGKVVAIKQIYKK--------PMNSPFSMSLIMKT 119
+ +Y+IG+ +G G F V + +TGK A+K I K P N+ S I+ +
Sbjct: 195 LEKYKIGKVIGDGNFAVVKECIDRSTGKEFALKIIDKAKCCGKQCAPSNTDTSCEAIVGS 254
Query: 120 MKRYESISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVL 179
+ ++E VS +R ++ HPN+I L+E +++ + +++L+ L
Sbjct: 255 TEH---------LIENEVSILR-------RVKHPNIIMLVEEMET--ATELFLVMELVKG 296
Query: 180 GELQWSRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQN 239
G+L FD I + E ++ +++N L+YL G I+HRD+KP+N
Sbjct: 297 GDL-------FDAITSSTKY-------TERDGSAMVYNLANALRYLHGLSIVHRDIKPEN 342
Query: 240 ILL---DPVYHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNF 296
+L+ SL++ DFG + +V E L + GTP + APE+
Sbjct: 343 LLVCEYPDGTKSLKLGDFGLATVV---------------EGPLYTVCGTPTYVAPEII-- 385
Query: 297 AEGSAHASNEQPFKIDVWSLGITVYAILYNVLPFWGETEF--DTYNLICHRQLKPDVHNS 354
A K+D+W+ G+ Y +L PF E D ++ I +L+
Sbjct: 386 ------AETGYGLKVDIWAAGVITYILLCGFPPFRSENNLQEDLFDQILAGKLEFPAPYW 439
Query: 355 SNIYGWIHEYVVNRMLSKNTASRPTTSNIL 384
NI E ++++ML N +R T IL
Sbjct: 440 DNITDSAKE-LISQMLQVNVEARCTAGQIL 468
>At5g04870 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 610
Score = 89.7 bits (221), Expect = 8e-18
Identities = 94/349 (26%), Positives = 139/349 (38%), Gaps = 74/349 (21%)
Query: 44 KTKIIERYVXXXXXXXXXQEEHAQKFVNQYRIGERLGCGQFGTVYK--GHTTGKVVAIKQ 101
K K ++R + + F Y +G +LG GQFGT + TTGK A K
Sbjct: 121 KPKHMKRVSSAGLRTESVLQRKTENFKEFYSLGRKLGQGQFGTTFLCVEKTTGKEFACKS 180
Query: 102 IYKKPMNSPFSMSLIMKTMKRYESISGDVLIMEMNVSKIRWECFVTSKL-NHPNVIQLLE 160
I K+ L+ + +V +R E + L HPNVI +
Sbjct: 181 IAKRK------------------------LLTDEDVEDVRREIQIMHHLAGHPNVISIKG 216
Query: 161 CLDSPYSDQIWLIQPLAVLGELQWSRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISN 220
+ + + L+ GEL FD I Q RG E A ++ I
Sbjct: 217 AYEDVVA--VHLVMECCAGGEL-------FDRIIQ-----RGHY--TERKAAELTRTIVG 260
Query: 221 GLQYLQGQGIIHRDLKPQNILLDPVYHS--LRISDFGCSLIVPSKLPFKDGRLQDLFEKE 278
++ G++HRDLKP+N L + L+ DFG S+ F D
Sbjct: 261 VVEACHSLGVMHRDLKPENFLFVSKHEDSLLKTIDFGLSMFFKPDDVFTD---------- 310
Query: 279 LNKIVGTPLFTAPELCNFAEGSAHASNEQPFKIDVWSLGITVYAILYNVLPFWGETEFDT 338
+VG+P + APE+ G + DVWS G+ VY +L V PFW ETE
Sbjct: 311 ---VVGSPYYVAPEVLRKRYGP---------EADVWSAGVIVYILLSGVPPFWAETEQGI 358
Query: 339 YNLICHRQLKPDVHNSSNIYGWIHEY---VVNRMLSKNTASRPTTSNIL 384
+ + H D+ SS+ + I E +V +ML ++ R T +L
Sbjct: 359 FEQVLH----GDLDFSSDPWPSISESAKDLVRKMLVRDPKKRLTAHQVL 403
>At3g01090 [T] KOG0583 Serine/threonine protein kinase
Length = 512
Score = 89.7 bits (221), Expect = 8e-18
Identities = 79/266 (29%), Positives = 124/266 (45%), Gaps = 63/266 (23%)
Query: 67 QKFVNQYRIGERLGCGQFGTVYKGH--TTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYE 124
+ + Y++G LG G FG V TG VAIK + ++ + +
Sbjct: 13 ESILPNYKLGRTLGIGSFGRVKIAEHALTGHKVAIKILNRRKIKN--------------- 57
Query: 125 SISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQW 184
MEM K+R E + HP++I+L E +++P I+L+ GEL
Sbjct: 58 --------MEME-EKVRREIKILRLFMHPHIIRLYEVIETP--TDIYLVMEYVNSGEL-- 104
Query: 185 SRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDP 244
FD I + +G+L E+ A I +G++Y ++HRDLKP+N+LLD
Sbjct: 105 -----FDYIVE-----KGRLQ--EDEARNFFQQIISGVEYCHRNMVVHRDLKPENLLLDS 152
Query: 245 VYHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHAS 304
+++I+DFG S I+ +DG L G+P + APE+ + G +A
Sbjct: 153 KC-NVKIADFGLSNIM------RDGHF-------LKTSCGSPNYAAPEVIS---GKLYAG 195
Query: 305 NEQPFKIDVWSLGITVYAILYNVLPF 330
E +DVWS G+ +YA+L LPF
Sbjct: 196 PE----VDVWSCGVILYALLCGTLPF 217
>YDR507c [D] KOG0588 Serine/threonine protein kinase
Length = 1142
Score = 89.4 bits (220), Expect = 1e-17
Identities = 76/267 (28%), Positives = 126/267 (46%), Gaps = 57/267 (21%)
Query: 70 VNQYRIGERLGCGQFGTVY--KGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESIS 127
+ +++GE LG G G V + +TG+ A+K I K N+ ++S
Sbjct: 16 IGPWKLGETLGLGSTGKVQLARNGSTGQEAAVKVISKAVFNTG--------------NVS 61
Query: 128 GDVLIMEMNVSKIRW----ECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQ 183
G ++ + + E + LNHPNV++L + ++ + ++L+ A GEL
Sbjct: 62 GTSIVGSTTPDALPYGIEREIIIMKLLNHPNVLRLYDVWET--NTDLYLVLEYAEKGEL- 118
Query: 184 WSRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLD 243
F+L+ + RG L E A++ I G+ Y GI+HRDLKP+N+LLD
Sbjct: 119 ------FNLLVE-----RGPLPEHE--AIRFFRQIIIGVSYCHALGIVHRDLKPENLLLD 165
Query: 244 PVYHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHA 303
Y +++I+DFG + + +G+L L G+P + APE+ +
Sbjct: 166 HKY-NIKIADFGMAALE------TEGKL-------LETSCGSPHYAAPEIVS-------G 204
Query: 304 SNEQPFKIDVWSLGITVYAILYNVLPF 330
Q F DVWS G+ ++A+L LPF
Sbjct: 205 IPYQGFASDVWSCGVILFALLTGRLPF 231
>SPCC320.12c [D] KOG0580 Serine/threonine protein kinase
Length = 384
Score = 89.4 bits (220), Expect = 1e-17
Identities = 87/325 (26%), Positives = 134/325 (40%), Gaps = 83/325 (25%)
Query: 70 VNQYRIGERLGCGQFGTVY--KGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESIS 127
+ + IG+ LG G+FG VY K TG +VA+K ++K
Sbjct: 115 IGMFEIGKPLGKGKFGRVYLAKEKKTGFIVALKTLHKSE--------------------- 153
Query: 128 GDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRE 187
L+ ++R E + S L H N+++L +I+LI A GEL
Sbjct: 154 ---LVQSKIEKQVRREIEIQSNLRHKNILRLYGHFHD--EKRIYLILEFAGRGEL----- 203
Query: 188 SKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYH 247
+ + + K F EE A K + ++N L YL + +IHRD+KP+NILL +
Sbjct: 204 --YQHLRRAKRFS-------EEVASKYIFQMANALSYLHKKHVIHRDIKPENILLG-IDG 253
Query: 248 SLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQ 307
+++SDFG S+ PS + GT + PE+ EG H
Sbjct: 254 EIKLSDFGWSVHAPS--------------NRRTTLCGTLDYLPPEM---VEGKEHTE--- 293
Query: 308 PFKIDVWSLGITVYAILYNVLPFWGETEFD-TYNLICHRQLK------PDVHNSSNIYGW 360
K+D+WSLG+ Y L PF + TY I LK PD +
Sbjct: 294 --KVDLWSLGVLTYEFLVGAPPFEDMSGHSATYKRIAKVDLKIPSFVPPDARD------- 344
Query: 361 IHEYVVNRMLSKNTASRPTTSNILR 385
+++R+L N R + ++R
Sbjct: 345 ----LISRLLQHNPEKRMSLEQVMR 365
>Hs4826684_1 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 370
Score = 89.4 bits (220), Expect = 1e-17
Identities = 89/318 (27%), Positives = 134/318 (41%), Gaps = 64/318 (20%)
Query: 73 YRIGERLGCGQFGTVYKGH--TTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISGDV 130
Y GE LG GQF V K +TG A K I K+ +T +S +
Sbjct: 13 YDTGEELGSGQFAVVKKCREKSTGLQYAAKFIKKR------------RTKSSRRGVSRED 60
Query: 131 LIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESKF 190
+ E+++ K ++ HPNVI L E ++ + LI L GEL F
Sbjct: 61 IEREVSILK---------EIQHPNVITLHEVYEN--KTDVILILELVAGGEL-------F 102
Query: 191 DLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILL---DPVYH 247
D + + +S EE A + L I NG+ YL I H DLKP+NI+L +
Sbjct: 103 DFLAEKESL-------TEEEATEFLKQILNGVYYLHSLQIAHFDLKPENIMLLDRNVPKP 155
Query: 248 SLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQ 307
++I DFG + + F E I GTP F APE+ N+ A
Sbjct: 156 RIKIIDFGLAHKID-------------FGNEFKNIFGTPEFVAPEIVNYEPLGLEA---- 198
Query: 308 PFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIYGWIHEYVVN 367
D+WS+G+ Y +L PF G+T+ +T + + + SN ++ +
Sbjct: 199 ----DMWSIGVITYILLSGASPFLGDTKQETLANVSAVNYEFEDEYFSNTSALAKDF-IR 253
Query: 368 RMLSKNTASRPTTSNILR 385
R+L K+ R T + L+
Sbjct: 254 RLLVKDPKKRMTIQDSLQ 271
>At4g04720 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 531
Score = 89.0 bits (219), Expect = 1e-17
Identities = 87/328 (26%), Positives = 139/328 (41%), Gaps = 75/328 (22%)
Query: 64 EHAQKFVNQYRIGERLGCGQFGTVY--KGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMK 121
E +KF Y +G+ LG GQFG Y K TG A K I K+ + S + + ++
Sbjct: 74 EDIRKF---YSLGKELGRGQFGITYMCKEIGTGNTYACKSILKRKLISKQDKEDVKREIQ 130
Query: 122 RYESISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGE 181
+ +SG PN++++ + S I L+ L GE
Sbjct: 131 IMQYLSGQ-----------------------PNIVEIKGAYEDRQS--IHLVMELCAGGE 165
Query: 182 LQWSRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNIL 241
L FD I Q E A ++ I N +Q G++HRDLKP+N L
Sbjct: 166 L-------FDRII-------AQGHYSERAAAGIIRSIVNVVQICHFMGVVHRDLKPENFL 211
Query: 242 LDPVYHS--LRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEG 299
L + L+ +DFG S+ + ++D IVG+ + APE+ + G
Sbjct: 212 LSSKEENAMLKATDFGLSVFIEEGKVYRD-------------IVGSAYYVAPEVLRRSYG 258
Query: 300 SAHASNEQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIYG 359
+ID+WS G+ +Y +L V PFW E E ++ + +K ++ S +
Sbjct: 259 K---------EIDIWSAGVILYILLSGVPPFWAENEKGIFDEV----IKGEIDFVSEPWP 305
Query: 360 WIHEY---VVNRMLSKNTASRPTTSNIL 384
I E +V +ML+K+ R T + +L
Sbjct: 306 SISESAKDLVRKMLTKDPKRRITAAQVL 333
>At1g08650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 284
Score = 89.0 bits (219), Expect = 1e-17
Identities = 79/319 (24%), Positives = 142/319 (43%), Gaps = 66/319 (20%)
Query: 71 NQYRIGERLGCGQFGTVYKGHT--TGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISG 128
N+Y+I E +G G+FGTV + + TG A K I K ++ + + K +S
Sbjct: 13 NKYQICEEIGRGRFGTVSRVYAPATGDFFACKTIDKASLSDDLDRACLDNEPKLMALLS- 71
Query: 129 DVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRES 188
HPN++Q+ + +D+ + L++ EL S
Sbjct: 72 ----------------------YHPNIVQIHDLIDTDST--------LSIFMELVHPSVS 101
Query: 189 KFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYHS 248
+D + +F+ Q S FA ++L +S+ +Y G++HRD+KP+NIL+D +
Sbjct: 102 IYDRLVSSGTFFEPQTAS---FAKQILQALSHCHRY----GVVHRDIKPENILVDLRNDT 154
Query: 249 LRISDFGCSLIVPSKLPFKDGRLQDLFEKELNK-IVGTPLFTAPE-LCNFAEGSAHASNE 306
++I DFG + L E E + +VGTP + APE L ++ G
Sbjct: 155 VKICDFGSGIW--------------LGEGETTEGVVGTPYYVAPEVLMGYSYGE------ 194
Query: 307 QPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIYGWIHEYVV 366
K+D+WS G+ +Y +L PF+GET + + + L+ + ++ +
Sbjct: 195 ---KVDLWSAGVVLYTMLAGTPPFYGETAEEIFEAVLRGNLRFPTKIFRGVSSMAKDF-L 250
Query: 367 NRMLSKNTASRPTTSNILR 385
+++ K+ + R + LR
Sbjct: 251 RKLICKDASRRFSAEQALR 269
>At5g01810 [T] KOG0583 Serine/threonine protein kinase
Length = 421
Score = 88.2 bits (217), Expect = 2e-17
Identities = 87/329 (26%), Positives = 142/329 (42%), Gaps = 72/329 (21%)
Query: 63 EEHAQKFVNQYRIGERLGCGQFGTVYKGH--TTGKVVAIKQIYKKPMNSPFSMSLIMKTM 120
E+ + +Y +G+ LG G F VY TG VAIK I K+ I+K +
Sbjct: 2 EKKGSVLMLRYEVGKFLGQGTFAKVYHARHLKTGDSVAIKVIDKER---------ILK-V 51
Query: 121 KRYESISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLG 180
E I ++ M + L HPN+++L E + + +I+ + G
Sbjct: 52 GMTEQIKREISAMRL--------------LRHPNIVELHEVMAT--KSKIYFVMEHVKGG 95
Query: 181 ELQWSRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNI 240
EL + G+L E+ A K + + + +G+ HRDLKP+N+
Sbjct: 96 EL-------------FNKVSTGKLR--EDVARKYFQQLVRAVDFCHSRGVCHRDLKPENL 140
Query: 241 LLDPVYHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGS 300
LLD + +L+ISDFG S + D R QD L+ GTP + APE+ +
Sbjct: 141 LLDE-HGNLKISDFGLSAL-------SDSRRQDGL---LHTTCGTPAYVAPEVIS----- 184
Query: 301 AHASNEQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIYGW 360
+ FK DVWS G+ ++ +L LPF + Y I ++K W
Sbjct: 185 --RNGYDGFKADVWSCGVILFVLLAGYLPFRDSNLMELYKKIGKAEVK--------FPNW 234
Query: 361 I---HEYVVNRMLSKNTASRPTTSNILRT 386
+ + ++ R+L N +R +T I+++
Sbjct: 235 LAPGAKRLLKRILDPNPNTRVSTEKIMKS 263
>At2g38490 [T] KOG0583 Serine/threonine protein kinase
Length = 431
Score = 88.2 bits (217), Expect = 2e-17
Identities = 89/328 (27%), Positives = 135/328 (41%), Gaps = 72/328 (21%)
Query: 63 EEHAQKFVNQYRIGERLGCGQFGTVYKGHTT---GKVVAIKQIYKKPMNSPFSMSLIMKT 119
+++ +Y +G+ LG G F VY+ G+ VAIK + KK + +
Sbjct: 18 DDNKSALFGKYDLGKLLGSGAFAKVYQAEDLQNGGESVAIKVVQKKRLKDGLT------- 70
Query: 120 MKRYESISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVL 179
+ ++ E V +L HP+++ L E L + +I+ + LA
Sbjct: 71 ------------------AHVKREISVMRRLRHPHIVLLSEVLAT--KTKIYFVMELAKG 110
Query: 180 GELQWSRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQN 239
GEL +SR + E Y QL S ++Y +G+ HRDLKP+N
Sbjct: 111 GEL-FSRVTSNRFTESLSRKYFRQLISA--------------VRYCHARGVFHRDLKPEN 155
Query: 240 ILLDPVYHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELC--NFA 297
+LLD L++SDFG S + P DG L L GTP + APEL
Sbjct: 156 LLLDE-NRDLKVSDFGLSAMKEQIHP--DGMLHTL--------CGTPAYVAPELLLKKGY 204
Query: 298 EGSAHASNEQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNI 357
+GS K D+WS G+ ++ + LPF Y I Q K SS++
Sbjct: 205 DGS---------KADIWSCGVVLFLLNAGYLPFRDPNIMGLYRKIHKAQYKLPDWTSSDL 255
Query: 358 YGWIHEYVVNRMLSKNTASRPTTSNILR 385
++ R+L N R T IL+
Sbjct: 256 -----RKLLRRLLEPNPELRITVEEILK 278
>At5g10930 [T] KOG0583 Serine/threonine protein kinase
Length = 445
Score = 87.8 bits (216), Expect = 3e-17
Identities = 79/282 (28%), Positives = 122/282 (43%), Gaps = 60/282 (21%)
Query: 63 EEHAQKFVNQYRIGERLGCGQFGTVYKGHTT--GKVVAIKQIYKKPMNSPFSMSLIMKTM 120
EE + +Y +G LG G F VY G G+ VAIK I K +MK
Sbjct: 2 EEERRVLFGKYEMGRLLGKGTFAKVYYGKEIIGGECVAIKVINKDQ---------VMKRP 52
Query: 121 KRYESISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLG 180
E I ++ IM++ + HPN+++L E + + +I+ + G
Sbjct: 53 GMMEQIKREISIMKL--------------VRHPNIVELKEVMAT--KTKIFFVMEFVKGG 96
Query: 181 ELQWSRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNI 240
EL + +G+L E+ A + + + + Y +G+ HRDLKP+N+
Sbjct: 97 EL-------------FCKISKGKLH--EDAARRYFQQLISAVDYCHSRGVSHRDLKPENL 141
Query: 241 LLDPVYHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGS 300
LLD L+ISDFG S + P ++ +DG L+ GTP + APE+
Sbjct: 142 LLDE-NGDLKISDFGLSAL-PEQI-LQDGL--------LHTQCGTPAYVAPEVLK----- 185
Query: 301 AHASNEQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLI 342
K D+WS G+ +Y +L LPF E + Y I
Sbjct: 186 --KKGYDGAKADIWSCGVVLYVLLAGCLPFQDENLMNMYRKI 225
>At3g10660 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 646
Score = 87.8 bits (216), Expect = 3e-17
Identities = 101/378 (26%), Positives = 150/378 (38%), Gaps = 83/378 (21%)
Query: 17 QPMSTDPESYFQIIDEQQKKLELGVISKTKIIERYVXXXXXXXXXQEEHAQKFVNQYRIG 76
+P +T PE+ + E + + + K K + R + + F Y +G
Sbjct: 135 KPETTKPETTSETKPETKAEPQ-----KPKHMRRVSSAGLRTESVLQRKTENFKEFYSLG 189
Query: 77 ERLGCGQFGTVY----KGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISGDVLI 132
+LG GQFGT + KG TG A K I K+ L+
Sbjct: 190 RKLGQGQFGTTFLCLEKG--TGNEYACKSISKRK------------------------LL 223
Query: 133 MEMNVSKIRWECFVTSKL-NHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESKFD 191
+ +V +R E + L HPNVI + + + + L+ L GEL FD
Sbjct: 224 TDEDVEDVRREIQIMHHLAGHPNVISIKGAYEDVVA--VHLVMELCSGGEL-------FD 274
Query: 192 LIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYHS--L 249
I Q RG E A ++ I L+ G++HRDLKP+N L L
Sbjct: 275 RIIQ-----RGHY--TERKAAELARTIVGVLEACHSLGVMHRDLKPENFLFVSREEDSLL 327
Query: 250 RISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQPF 309
+ DFG S+ F D +VG+P + APE+ G
Sbjct: 328 KTIDFGLSMFFKPDEVFTD-------------VVGSPYYVAPEVLRKRYGP--------- 365
Query: 310 KIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIYGWIHEY---VV 366
+ DVWS G+ VY +L V PFW ETE + + H D+ SS+ + I E +V
Sbjct: 366 ESDVWSAGVIVYILLSGVPPFWAETEQGIFEQVLH----GDLDFSSDPWPSISESAKDLV 421
Query: 367 NRMLSKNTASRPTTSNIL 384
+ML ++ R T +L
Sbjct: 422 RKMLVRDPKRRLTAHQVL 439
>At2g35890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 520
Score = 87.8 bits (216), Expect = 3e-17
Identities = 95/370 (25%), Positives = 145/370 (38%), Gaps = 87/370 (23%)
Query: 31 DEQQKKLELGVIS---KTKIIERYVXXXXXXXXXQEEHAQKFVNQYRIGERLGCGQFGTV 87
DE+ KK + + K + R + + Y +G +LG GQFGT
Sbjct: 87 DEEYKKRAIACANSKRKAHNVRRLMSAGLQAESVLKTKTGHLKEYYNLGSKLGHGQFGTT 146
Query: 88 Y----KGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISGDVLIMEMNVSKIRWE 143
+ KG TG+ A K I K+ + + E +V +R E
Sbjct: 147 FVCVEKG--TGEEYACKSIPKRKLEN------------------------EEDVEDVRRE 180
Query: 144 CFVTSKL-NHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESKFDLIEQWKSFYRG 202
+ L PNVI + + S + ++ L GEL FD I + RG
Sbjct: 181 IEIMKHLLGQPNVISIKGAYED--SVAVHMVMELCRGGEL-------FDRIVE-----RG 226
Query: 203 QLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILL--DPVYHSLRISDFGCSLIV 260
E A + I +Q G++HRDLKP+N L D L+ DFG S+ +
Sbjct: 227 HYS--ERKAAHLAKVILGVVQTCHSLGVMHRDLKPENFLFVNDDEDSPLKAIDFGLSMFL 284
Query: 261 PSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQPFKIDVWSLGITV 320
F D +VG+P + APE+ N G + D+WS G+ +
Sbjct: 285 KPGENFTD-------------VVGSPYYIAPEVLNKNYGP---------EADIWSAGVMI 322
Query: 321 YAILYNVLPFWGETEFDTYNLICHRQLK------PDVHNSSNIYGWIHEYVVNRMLSKNT 374
Y +L PFWGETE + +N + +L P V S+ + ++ +ML +N
Sbjct: 323 YVLLSGSAPFWGETEEEIFNEVLEGELDLTSDPWPQVSESA-------KDLIRKMLERNP 375
Query: 375 ASRPTTSNIL 384
R T +L
Sbjct: 376 IQRLTAQQVL 385
>At4g21940 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 554
Score = 87.4 bits (215), Expect = 4e-17
Identities = 86/321 (26%), Positives = 136/321 (41%), Gaps = 76/321 (23%)
Query: 73 YRIGERLGCGQFGTVY--KGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISGDV 130
Y +G+ LG GQFG Y K ++TG A K I K+ + + + + ++ + +SG
Sbjct: 102 YTLGKELGRGQFGITYTCKENSTGNTYACKSILKRKLTRKQDIDDVKREIQIMQYLSGQE 161
Query: 131 LIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQ--IWLIQPLAVLGELQWSRES 188
I+E+ Y D+ I L+ L EL
Sbjct: 162 NIVEIK---------------------------GAYEDRQSIHLVMELCGGSEL------ 188
Query: 189 KFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYHS 248
FD I Q E+ A V+ + N +Q G+IHRDLKP+N LL +
Sbjct: 189 -FDRII-------AQGHYSEKAAAGVIRSVLNVVQICHFMGVIHRDLKPENFLLASTDEN 240
Query: 249 --LRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNE 306
L+ +DFG S+ + ++D IVG+ + APE+ + G
Sbjct: 241 AMLKATDFGLSVFIEEGKVYRD-------------IVGSAYYVAPEVLRRSYGK------ 281
Query: 307 QPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIYGWIHEY-- 364
+ID+WS GI +Y +L V PFW ETE +N I +K ++ S + I E
Sbjct: 282 ---EIDIWSAGIILYILLCGVPPFWSETEKGIFNEI----IKGEIDFDSQPWPSISESAK 334
Query: 365 -VVNRMLSKNTASRPTTSNIL 384
+V ++L+K+ R + + L
Sbjct: 335 DLVRKLLTKDPKQRISAAQAL 355
>CE28643 [T] KOG0583 Serine/threonine protein kinase
Length = 564
Score = 87.0 bits (214), Expect = 5e-17
Identities = 85/271 (31%), Positives = 125/271 (45%), Gaps = 63/271 (23%)
Query: 62 QEEHAQKFVNQYRIGERLGCGQFGTVYKG--HTTGKVVAIKQIYKKPMNSPFSMSLIMKT 119
QE AQ + Y + E LG G FG V G TT VA+K + ++ + S
Sbjct: 14 QELKAQIKIGHYILKETLGVGTFGKVKVGIHETTQYKVAVKILNRQKIKSL--------- 64
Query: 120 MKRYESISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVL 179
DV V KIR E S HP++I+L + + +P I++I
Sbjct: 65 ---------DV------VGKIRREIQNLSLFRHPHIIRLYQVISTP--SDIFMIMEHVSG 107
Query: 180 GELQWSRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQN 239
GEL FD I + G+L + E A + I +G+ Y ++HRDLKP+N
Sbjct: 108 GEL-------FDYIVK-----HGRLKTAE--ARRFFQQIISGVDYCHRHMVVHRDLKPEN 153
Query: 240 ILLDPVYHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEG 299
+LLD ++++I+DFG S I+ DG L G+P + APE+ + G
Sbjct: 154 LLLDE-QNNVKIADFGLSNIM------TDGDF-------LRTSCGSPNYAAPEVIS---G 196
Query: 300 SAHASNEQPFKIDVWSLGITVYAILYNVLPF 330
+A E +DVWS G+ +YA+L LPF
Sbjct: 197 KLYAGPE----VDVWSCGVILYALLCGTLPF 223
>CE07458 [T] KOG0583 Serine/threonine protein kinase
Length = 562
Score = 87.0 bits (214), Expect = 5e-17
Identities = 85/271 (31%), Positives = 125/271 (45%), Gaps = 63/271 (23%)
Query: 62 QEEHAQKFVNQYRIGERLGCGQFGTVYKG--HTTGKVVAIKQIYKKPMNSPFSMSLIMKT 119
QE AQ + Y + E LG G FG V G TT VA+K + ++ + S
Sbjct: 14 QELKAQIKIGHYILKETLGVGTFGKVKVGIHETTQYKVAVKILNRQKIKSL--------- 64
Query: 120 MKRYESISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVL 179
DV V KIR E S HP++I+L + + +P I++I
Sbjct: 65 ---------DV------VGKIRREIQNLSLFRHPHIIRLYQVISTP--SDIFMIMEHVSG 107
Query: 180 GELQWSRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQN 239
GEL FD I + G+L + E A + I +G+ Y ++HRDLKP+N
Sbjct: 108 GEL-------FDYIVK-----HGRLKTAE--ARRFFQQIISGVDYCHRHMVVHRDLKPEN 153
Query: 240 ILLDPVYHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEG 299
+LLD ++++I+DFG S I+ DG L G+P + APE+ + G
Sbjct: 154 LLLDE-QNNVKIADFGLSNIM------TDGDF-------LRTSCGSPNYAAPEVIS---G 196
Query: 300 SAHASNEQPFKIDVWSLGITVYAILYNVLPF 330
+A E +DVWS G+ +YA+L LPF
Sbjct: 197 KLYAGPE----VDVWSCGVILYALLCGTLPF 223
>At5g25110 [T] KOG0583 Serine/threonine protein kinase
Length = 460
Score = 86.3 bits (212), Expect = 9e-17
Identities = 79/283 (27%), Positives = 123/283 (42%), Gaps = 61/283 (21%)
Query: 62 QEEHAQKFVNQYRIGERLGCGQFGTVYKGH--TTGKVVAIKQIYKKPMNSPFSMSLIMKT 119
+++ + +Y +G LG G FG VY G TTG+ VAIK I K + M
Sbjct: 4 EQQQLRVLFAKYEMGRLLGKGTFGKVYYGKEITTGESVAIKIINKDQVKREGMM------ 57
Query: 120 MKRYESISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVL 179
E I ++ IM + + HPN+++L E + + +I+ I
Sbjct: 58 ----EQIKREISIMRL--------------VRHPNIVELKEVMAT--KTKIFFIMEYVKG 97
Query: 180 GELQWSRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQN 239
GEL + +G+L E+ A K + + + + +G+ HRDLKP+N
Sbjct: 98 GEL-------------FSKIVKGKLK--EDSARKYFQQLISAVDFCHSRGVSHRDLKPEN 142
Query: 240 ILLDPVYHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEG 299
+L+D L++SDFG S + P ++ +DG L+ GTP + APE+
Sbjct: 143 LLVDE-NGDLKVSDFGLSAL-PEQI-LQDGL--------LHTQCGTPAYVAPEV------ 185
Query: 300 SAHASNEQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLI 342
K D+WS GI +Y +L LPF E Y I
Sbjct: 186 -LRKKGYDGAKGDIWSCGIILYVLLAGFLPFQDENLMKMYRKI 227
>7299322 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 434
Score = 86.3 bits (212), Expect = 9e-17
Identities = 75/263 (28%), Positives = 123/263 (46%), Gaps = 63/263 (23%)
Query: 72 QYRIGERLGCGQFGTVYKG--HTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISGD 129
++ I ++LG G +G V G TG+ VAIK I K + +
Sbjct: 81 KFDIIKKLGQGTYGKVQLGINKETGQEVAIKTIKKCKIEA-------------------- 120
Query: 130 VLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESK 189
E ++ +IR E + S ++HPN+I + E ++ +++ L+ A GEL
Sbjct: 121 ----EADLVRIRREVQIMSSVHHPNIIHIYEVFEN--REKMVLVMEFAAGGEL------- 167
Query: 190 FDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYHSL 249
+D + + K EE A ++ ++ + Y I HRDLK +NILLD ++
Sbjct: 168 YDYLSERKVL-------TEEEARRIFRQVATAVYYCHKHKICHRDLKLENILLDEKGNA- 219
Query: 250 RISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQPF 309
+I+DFG S + F D RL L G+PL+ +PE+ EG+ + E
Sbjct: 220 KIADFGLSNV------FDDQRL-------LGTFCGSPLYASPEI---VEGTPYQGPE--- 260
Query: 310 KIDVWSLGITVYAILYNVLPFWG 332
+D WSLG+ +Y ++Y +PF G
Sbjct: 261 -VDCWSLGVLLYTLVYGSMPFDG 282
>At1g50230 [R] KOG0597 Serine-threonine protein kinase FUSED
Length = 269
Score = 85.9 bits (211), Expect = 1e-16
Identities = 82/279 (29%), Positives = 123/279 (43%), Gaps = 72/279 (25%)
Query: 70 VNQYRIGERLGCGQFGTVYKGHT--TGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESIS 127
V Y + E +G G FG VYKG TG+ VA+K I K+ KT K
Sbjct: 3 VEDYHVIELVGEGSFGRVYKGRRKYTGQTVAMKFIMKQG-----------KTDK------ 45
Query: 128 GDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRE 187
++ +R E + KL H N+I++L+ ++ + + ++ A GEL
Sbjct: 46 --------DIHSLRQEIEILRKLKHENIIEMLDSFEN--AREFCVVTEFAQ-GEL----- 89
Query: 188 SKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYH 247
F+++E K Q+ ++ + VK L YL IIHRD+KPQNIL+
Sbjct: 90 --FEILEDDKCLPEEQVQAIAKQLVKAL-------DYLHSNRIIHRDMKPQNILIG-AGS 139
Query: 248 SLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQ 307
+++ DFG + R L I GTPL+ APEL EQ
Sbjct: 140 VVKLCDFGFA------------RAMSTNTVVLRSIKGTPLYMAPELV----------KEQ 177
Query: 308 PF--KIDVWSLGITVYAILYNVLPFWGETEFDTYNLICH 344
P+ +D+WSLG+ +Y + PF+ + Y LI H
Sbjct: 178 PYDRTVDLWSLGVILYELYVGQPPFYTNS---VYALIRH 213
>CE26793_1 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 795
Score = 85.9 bits (211), Expect = 1e-16
Identities = 77/268 (28%), Positives = 124/268 (45%), Gaps = 63/268 (23%)
Query: 67 QKFVNQYRIGERLGCGQFGTVYKG--HTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYE 124
+K +++ I ++LG G +G V H + VA+K I K + S
Sbjct: 69 KKEKHRFEITKKLGSGTYGKVSLAYDHKFDREVAVKLIKKSAIES--------------- 113
Query: 125 SISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQW 184
+ ++ +IR E + S LNHPN+IQ+ E ++ D+I L+ + GEL
Sbjct: 114 ---------KADLVRIRREIRIMSALNHPNIIQIYEVFEN--KDKIILVMEYSSGGEL-- 160
Query: 185 SRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDP 244
+D + + G L E A ++ I++ + Y + HRDLK +NILLD
Sbjct: 161 -----YDYVSRC-----GSLPEAE--ARRIFRQITSAVLYCHKHRVAHRDLKLENILLDQ 208
Query: 245 VYHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHAS 304
++ +I+DFG S F D L L G+PL+ +PE+ N G+ +
Sbjct: 209 -NNNAKIADFGLSNY------FADKNL-------LTTFCGSPLYASPEIIN---GTPYKG 251
Query: 305 NEQPFKIDVWSLGITVYAILYNVLPFWG 332
E +D WSLGI +Y ++Y +PF G
Sbjct: 252 PE----VDCWSLGILLYTLVYGSMPFDG 275
>Hs5453964 [T] KOG0583 Serine/threonine protein kinase
Length = 550
Score = 85.5 bits (210), Expect = 2e-16
Identities = 80/284 (28%), Positives = 128/284 (44%), Gaps = 63/284 (22%)
Query: 62 QEEHAQKFVNQYRIGERLGCGQFGTVYKG--HTTGKVVAIKQIYKKPMNSPFSMSLIMKT 119
Q+ + + Y +G+ LG G FG V G TG VA+K + ++ + S
Sbjct: 7 QKHDGRVKIGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSL--------- 57
Query: 120 MKRYESISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVL 179
DV V KIR E HP++I+L + + +P I+++
Sbjct: 58 ---------DV------VGKIRREIQNLKLFRHPHIIKLYQVISTP--SDIFMVMEYVSG 100
Query: 180 GELQWSRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQN 239
GEL FD I + G+LD E + ++ I +G+ Y ++HRDLKP+N
Sbjct: 101 GEL-------FDYICK-----NGRLDEKE--SRRLFQQILSGVDYCHRHMVVHRDLKPEN 146
Query: 240 ILLDPVYHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEG 299
+LLD + + +I+DFG S ++ DG L G+P + APE+ + G
Sbjct: 147 VLLD-AHMNAKIADFGLSNMM------SDGEF-------LRTSCGSPNYAAPEVIS---G 189
Query: 300 SAHASNEQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLIC 343
+A E +D+WS G+ +YA+L LPF + + IC
Sbjct: 190 RLYAGPE----VDIWSSGVILYALLCGTLPFDDDHVPTLFKKIC 229
>Hs13569922 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 628
Score = 85.5 bits (210), Expect = 2e-16
Identities = 76/272 (27%), Positives = 123/272 (44%), Gaps = 62/272 (22%)
Query: 62 QEEHAQKFVNQYRIGERLGCGQFGTVYKGH-TTGKVVAIKQIYKKPMNSPFSMSLIMKTM 120
+ H ++Y E LG G +G V K ++G++VAIK I K
Sbjct: 42 RHHHKHNLRHRYEFLETLGKGTYGKVKKARESSGRLVAIKSIRK---------------- 85
Query: 121 KRYESISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLG 180
D + E ++ IR E + S LNHP++I + E ++ S +I ++ A G
Sbjct: 86 --------DKIKDEQDLMHIRREIEIMSSLNHPHIIAIHEVFEN--SSKIVIVMEYASRG 135
Query: 181 ELQWSRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNI 240
+L +D I + R QL E A I + + Y ++HRDLK +NI
Sbjct: 136 DL-------YDYISE-----RQQLSERE--ARHFFRQIVSAVHYCHQNRVVHRDLKLENI 181
Query: 241 LLDPVYHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGS 300
LLD +++I+DFG S + + G+ F G+PL+ +PE+ N G
Sbjct: 182 LLD-ANGNIKIADFGLSNL------YHQGKFLQTF-------CGSPLYASPEIVN---GK 224
Query: 301 AHASNEQPFKIDVWSLGITVYAILYNVLPFWG 332
+ E +D WSLG+ +Y +++ +PF G
Sbjct: 225 PYTGPE----VDSWSLGVLLYILVHGTMPFDG 252
>7303019 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 913
Score = 85.5 bits (210), Expect = 2e-16
Identities = 76/321 (23%), Positives = 134/321 (41%), Gaps = 65/321 (20%)
Query: 69 FVNQYRIGERLGCGQFGTVYKGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISG 128
F +++ I E LG G+FG VYK G+ + L K +K +S
Sbjct: 274 FKSRFEIIEELGKGRFGIVYKVQERGQPEQL---------------LAAKVIKCIKSQDR 318
Query: 129 DVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRES 188
++ E+++ + L HP ++QL +SP +I ++ GEL
Sbjct: 319 QKVLEEISIMRA---------LQHPKLLQLAASFESPR--EIVMVMEYITGGEL------ 361
Query: 189 KFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDP-VYH 247
++ E + L + +G+ Y+ GQ ++H DLKP+NI+ H
Sbjct: 362 -------FERVVADDFTLTEMDCILFLRQVCDGVAYMHGQSVVHLDLKPENIMCHTRTSH 414
Query: 248 SLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQ 307
++I DFG + + +K P + + GTP F PE+ ++
Sbjct: 415 QIKIIDFGLAQRLDTKAPVR-------------VLFGTPEFIPPEIISYEPIG------- 454
Query: 308 PFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHN----SSNIYGWIHE 363
F+ D+WS+G+ Y +L + PF G+T+ +T++ I D S +I +
Sbjct: 455 -FQSDMWSVGVICYVLLSGLSPFMGDTDVETFSNITRADYDYDDEAFDCVSQEAKDFISQ 513
Query: 364 YVVNRMLSKNTASRPTTSNIL 384
+V+R + TA + S L
Sbjct: 514 LLVHRKEDRLTAQQCLASKWL 534
>At5g58380 [T] KOG0583 Serine/threonine protein kinase
Length = 464
Score = 85.1 bits (209), Expect = 2e-16
Identities = 83/325 (25%), Positives = 137/325 (41%), Gaps = 70/325 (21%)
Query: 63 EEHAQKFVNQYRIGERLGCGQFGTVYKGHT--TGKVVAIKQIYKKPMNSPFSMSLIMKTM 120
E ++Y +G LG G F VY G + T + VAIK I K+ + + LI
Sbjct: 2 ENKPSVLTDKYDVGRLLGQGTFAKVYYGRSILTNQSVAIKMIDKEKV---MKVGLI---- 54
Query: 121 KRYESISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLG 180
E I ++ +M + HPNV++L E + + +I+ + G
Sbjct: 55 ---EQIKREISVMRI--------------ARHPNVVELYEVMAT--KTRIYFVMEYCKGG 95
Query: 181 ELQWSRESKFDLIEQ--WKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQ 238
EL +++ +K L + WK FY+ + N + + + + HRD+KP+
Sbjct: 96 EL-FNKVAKGKLRDDVAWKYFYQ----------------LINAVDFCHSREVYHRDIKPE 138
Query: 239 NILLDPVYHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAE 298
N+LLD +L++SDFG S + K +DG L+ GTP + APE+ N
Sbjct: 139 NLLLDD-NENLKVSDFGLSALADCKR--QDGL--------LHTTCGTPAYVAPEVIN--- 184
Query: 299 GSAHASNEQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIY 358
K D+WS G+ ++ +L LPF + Y I K + +
Sbjct: 185 ----RKGYDGTKADIWSCGVVLFVLLAGYLPFHDSNLMEMYRKIGKADFKAPSWFAPEV- 239
Query: 359 GWIHEYVVNRMLSKNTASRPTTSNI 383
++ +ML N +R T + I
Sbjct: 240 ----RRLLCKMLDPNPETRITIARI 260
>At5g07070 [T] KOG0583 Serine/threonine protein kinase
Length = 456
Score = 85.1 bits (209), Expect = 2e-16
Identities = 77/285 (27%), Positives = 122/285 (42%), Gaps = 67/285 (23%)
Query: 63 EEHAQKFVNQYRIGERLGCGQFGTVYKGHT--TGKVVAIKQIYKKPMNSPFSMSLIMKTM 120
E +Y +G LG G F VY G + T + VAIK I K
Sbjct: 2 ENKPSVLTERYEVGRLLGQGTFAKVYFGRSNHTNESVAIKMIDKDK-------------- 47
Query: 121 KRYESISGDVLIMEMNVSK-IRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVL 179
+M + +S+ I+ E V HPNV++L E + + +I+ +
Sbjct: 48 -----------VMRVGLSQQIKREISVMRIAKHPNVVELYEVMAT--KSRIYFVIEYCKG 94
Query: 180 GELQWSRESKFDLIEQ--WKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKP 237
GEL +++ +K L E WK FY+ + + + + +G+ HRD+KP
Sbjct: 95 GEL-FNKVAKGKLKEDVAWKYFYQ----------------LISAVDFCHSRGVYHRDIKP 137
Query: 238 QNILLDPVYHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFA 297
+N+LLD +L++SDFG S + K +DG L+ GTP + APE+ N
Sbjct: 138 ENLLLDD-NDNLKVSDFGLSALADCKR--QDGL--------LHTTCGTPAYVAPEVIN-- 184
Query: 298 EGSAHASNEQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLI 342
+ K D+WS G+ ++ +L LPF + Y I
Sbjct: 185 -----RKGYEGTKADIWSCGVVLFVLLAGYLPFHDTNLMEMYRKI 224
>At3g57530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 560
Score = 85.1 bits (209), Expect = 2e-16
Identities = 80/269 (29%), Positives = 112/269 (40%), Gaps = 65/269 (24%)
Query: 71 NQYRIGERLGCGQFGTVY--KGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISG 128
++Y +G LG G+FG Y T V A K I KK + +T E +
Sbjct: 61 SKYTLGRELGRGEFGVTYLCTDKETDDVFACKSILKKKL----------RTAVDIEDVRR 110
Query: 129 DVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRES 188
+V IM HPNV+ L E + ++ + L+ L GEL
Sbjct: 111 EVEIMR-------------HMPEHPNVVTLKETYEDEHA--VHLVMELCEGGEL------ 149
Query: 189 KFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYHS 248
FD I RG E A V I +Q G++HRDLKP+N L +
Sbjct: 150 -FDRIVA-----RGHY--TERAAAAVTKTIMEVVQVCHKHGVMHRDLKPENFLFGNKKET 201
Query: 249 --LRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNE 306
L+ DFG S+ FK G + N+IVG+P + APE+ G
Sbjct: 202 APLKAIDFGLSVF------FKPG-------ERFNEIVGSPYYMAPEVLKRNYGP------ 242
Query: 307 QPFKIDVWSLGITVYAILYNVLPFWGETE 335
++D+WS G+ +Y +L V PFW ETE
Sbjct: 243 ---EVDIWSAGVILYILLCGVPPFWAETE 268
>At3g29160 [T] KOG0583 Serine/threonine protein kinase
Length = 512
Score = 85.1 bits (209), Expect = 2e-16
Identities = 75/266 (28%), Positives = 124/266 (46%), Gaps = 63/266 (23%)
Query: 67 QKFVNQYRIGERLGCGQFGTVYKGH--TTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYE 124
+ + Y++G+ LG G FG V TG VAIK + ++ + +
Sbjct: 14 ESILPNYKLGKTLGIGSFGKVKIAEHVVTGHKVAIKILNRRKIKN--------------- 58
Query: 125 SISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQW 184
MEM K+R E + HP++I+ E +++ + I+++ GEL
Sbjct: 59 --------MEME-EKVRREIKILRLFMHPHIIRQYEVIET--TSDIYVVMEYVKSGEL-- 105
Query: 185 SRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDP 244
FD I + +G+L E+ A I +G++Y ++HRDLKP+N+LLD
Sbjct: 106 -----FDYIVE-----KGRLQ--EDEARNFFQQIISGVEYCHRNMVVHRDLKPENLLLDS 153
Query: 245 VYHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHAS 304
+++I+DFG S ++ +DG L G+P + APE+ + G +A
Sbjct: 154 -RCNIKIADFGLSNVM------RDGHF-------LKTSCGSPNYAAPEVIS---GKLYAG 196
Query: 305 NEQPFKIDVWSLGITVYAILYNVLPF 330
E +DVWS G+ +YA+L LPF
Sbjct: 197 PE----VDVWSCGVILYALLCGTLPF 218
>At3g20410 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 541
Score = 85.1 bits (209), Expect = 2e-16
Identities = 83/325 (25%), Positives = 136/325 (41%), Gaps = 82/325 (25%)
Query: 73 YRIGERLGCGQFGTVY--KGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISGDV 130
Y +G+ LG GQFG Y ++TGK A K I KK + + + + ++ + +SG
Sbjct: 91 YTLGKELGRGQFGVTYLCTENSTGKKYACKSISKKKLVTKADKDDMRREIQIMQHLSGQ- 149
Query: 131 LIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQ--IWLIQPLAVLGELQWSRES 188
PN+++ Y D+ + L+ L GEL
Sbjct: 150 ----------------------PNIVEF----KGAYEDEKAVNLVMELCAGGEL------ 177
Query: 189 KFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYHS 248
FD I K Y E A V I N ++ G++HRDLKP+N LL
Sbjct: 178 -FDRIIA-KGHY------TERAAASVCRQIVNVVKICHFMGVLHRDLKPENFLLSSKDEK 229
Query: 249 --LRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNE 306
++ +DFG S+ + ++D IVG+ + APE+ G
Sbjct: 230 ALIKATDFGLSVFIEEGKVYRD-------------IVGSAYYVAPEVLRRRYGK------ 270
Query: 307 QPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLK------PDVHNSSNIYGW 360
++D+WS GI +Y +L V PFW ETE ++ I + P + +S+
Sbjct: 271 ---EVDIWSAGIILYILLSGVPPFWAETEKGIFDAILEGHIDFESQPWPSISSSA----- 322
Query: 361 IHEYVVNRMLSKNTASRPTTSNILR 385
+ +V RML+ + R + +++L+
Sbjct: 323 --KDLVRRMLTADPKRRISAADVLQ 345
>At1g50700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 521
Score = 85.1 bits (209), Expect = 2e-16
Identities = 85/325 (26%), Positives = 134/325 (41%), Gaps = 82/325 (25%)
Query: 73 YRIGERLGCGQFGTVY--KGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISGDV 130
Y + + LG GQFG Y +TGK A K I KK + + + + ++ + +SG
Sbjct: 73 YTLSKELGRGQFGVTYLCTEKSTGKRFACKSISKKKLVTKGDKEDMRREIQIMQHLSGQ- 131
Query: 131 LIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQ--IWLIQPLAVLGELQWSRES 188
PN+++ Y D+ + L+ L GEL
Sbjct: 132 ----------------------PNIVEF----KGAYEDEKAVNLVMELCAGGEL------ 159
Query: 189 KFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYHS 248
FD I K Y E A V I N + G++HRDLKP+N LL
Sbjct: 160 -FDRILA-KGHYS------ERAAASVCRQIVNVVNICHFMGVMHRDLKPENFLLSSKDEK 211
Query: 249 --LRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNE 306
++ +DFG S+ + +KD IVG+ + APE+ G
Sbjct: 212 ALIKATDFGLSVFIEEGRVYKD-------------IVGSAYYVAPEVLKRRYGK------ 252
Query: 307 QPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLK------PDVHNSSNIYGW 360
+ID+WS GI +Y +L V PFW ETE ++ I ++ P + NS+
Sbjct: 253 ---EIDIWSAGIILYILLSGVPPFWAETEKGIFDAILEGEIDFESQPWPSISNSA----- 304
Query: 361 IHEYVVNRMLSKNTASRPTTSNILR 385
+ +V RML+++ R + + +L+
Sbjct: 305 --KDLVRRMLTQDPKRRISAAEVLK 327
>At3g49370 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 594
Score = 84.7 bits (208), Expect = 3e-16
Identities = 78/326 (23%), Positives = 137/326 (41%), Gaps = 68/326 (20%)
Query: 66 AQKFVNQYRIGERLGCGQFG-----TVYKGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTM 120
A+ F +Y +G +G G FG KG G+ VA+K I K M S S+ + + +
Sbjct: 135 AKNFEGKYELGREVGRGHFGHTCWAKAKKGKIKGQTVAVKIISKSKMTSALSIEDVRREV 194
Query: 121 KRYESISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLG 180
K +++SG H ++++ + + SD ++++ L G
Sbjct: 195 KLLKALSG-----------------------HSHMVKFYDVFED--SDNVFVVMELCEGG 229
Query: 181 ELQWSRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNI 240
EL S ++ G+ E A ++L I + + QG++HRDLKP+N
Sbjct: 230 ELLDSILAR-----------GGRYPEAE--AKRILVQILSATAFFHLQGVVHRDLKPENF 276
Query: 241 LLDPVYHS--LRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAE 298
L L++ DFG S F++ LN +VG+ + APE+ + +
Sbjct: 277 LFTSKNEDAVLKVIDFGLSDYA-------------RFDQRLNDVVGSAYYVAPEVLHRSY 323
Query: 299 GSAHASNEQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIY 358
+ + D+WS+G+ Y +L PF+G TE + + D +I
Sbjct: 324 ST---------EADIWSIGVISYILLCGSRPFYGRTESAIFRCVLRANPNFDDLPWPSIS 374
Query: 359 GWIHEYVVNRMLSKNTASRPTTSNIL 384
++ V R+L+K+ R T + L
Sbjct: 375 PIAKDF-VKRLLNKDHRKRMTAAQAL 399
>At2g31500 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 582
Score = 84.7 bits (208), Expect = 3e-16
Identities = 88/321 (27%), Positives = 136/321 (41%), Gaps = 74/321 (23%)
Query: 72 QYRIGERLGCGQFGTVYKGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRY--ESISGD 129
+Y +G+ LG G+FG ++ + + T +R+ + IS +
Sbjct: 65 KYDLGKELGRGEFGVTHE------------------------CIEISTRERFACKRISKE 100
Query: 130 VLIMEMNVSKIRWECFVTSKL-NHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRES 188
L E++V +R E + L HPN++ E + D ++L+ + GEL
Sbjct: 101 KLRTEIDVEDVRREVEIMRCLPKHPNIVSFKEAFED--KDAVYLVMEICEGGEL------ 152
Query: 189 KFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYHS 248
FD I RG E A V I ++ G+IHRDLKP+N L +
Sbjct: 153 -FDRIVS-----RGHY--TERAAASVAKTILEVVKVCHEHGVIHRDLKPENFLFSNGTET 204
Query: 249 --LRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNE 306
L+ DFG S+ FK + N+IVG+P + APE+ G
Sbjct: 205 AQLKAIDFGLSIF------FKPAQ-------RFNEIVGSPYYMAPEVLRRNYGP------ 245
Query: 307 QPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIYGWI-HE-- 363
+IDVWS G+ +Y +L V PFW ETE I H ++ ++ + + + HE
Sbjct: 246 ---EIDVWSAGVILYILLCGVPPFWAETE----EGIAHAIVRGNIDFERDPWPKVSHEAK 298
Query: 364 YVVNRMLSKNTASRPTTSNIL 384
+V ML N SR T +L
Sbjct: 299 ELVKNMLDANPYSRLTVQEVL 319
>At1g76040 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 534
Score = 84.3 bits (207), Expect = 3e-16
Identities = 81/317 (25%), Positives = 130/317 (40%), Gaps = 68/317 (21%)
Query: 73 YRIGERLGCGQFGTVYK--GHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISGDV 130
Y + + LG GQFG YK + G+ A K I K+
Sbjct: 85 YDLHKELGRGQFGITYKCTDKSNGREYACKSISKRK------------------------ 120
Query: 131 LIMEMNVSKIRWECFVTSKLN-HPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESK 189
LI ++ +R E + L PN+++ + D + L+ L GEL
Sbjct: 121 LIRRKDIEDVRREVMILQHLTGQPNIVEFRGAYED--KDNLHLVMELCSGGEL------- 171
Query: 190 FDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILL--DPVYH 247
FD I + S+ E+ A + I N + G++HRDLKP+N LL +
Sbjct: 172 FDRIIKKGSYS-------EKEAANIFRQIVNVVHVCHFMGVVHRDLKPENFLLVSNEEDS 224
Query: 248 SLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQ 307
++ +DFG S+ + ++D IVG+ + APE+ + G
Sbjct: 225 PIKATDFGLSVFIEEGKVYRD-------------IVGSAYYVAPEVLHRNYGK------- 264
Query: 308 PFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIYGWIHEYVVN 367
+IDVWS G+ +Y +L V PFWGETE + I +L + I + ++
Sbjct: 265 --EIDVWSAGVMLYILLSGVPPFWGETEKTIFEAILEGKLDLETSPWPTISESAKD-LIR 321
Query: 368 RMLSKNTASRPTTSNIL 384
+ML ++ R T + L
Sbjct: 322 KMLIRDPKKRITAAEAL 338
>At1g35670 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 495
Score = 84.3 bits (207), Expect = 3e-16
Identities = 80/283 (28%), Positives = 124/283 (43%), Gaps = 69/283 (24%)
Query: 71 NQYRIGERLGCGQFGTVY--KGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISG 128
+ Y +G++LG GQFGT Y +T A K I K+ + + YE +
Sbjct: 24 DHYLLGKKLGQGQFGTTYLCTEKSTSANYACKSIPKRKL----------VCREDYEDVWR 73
Query: 129 DVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIW--LIQPLAVLGELQWSR 186
++ IM ++S+ HPNV+++ Y D ++ ++ + GEL
Sbjct: 74 EIQIMH-HLSE------------HPNVVRI----KGTYEDSVFVHIVMEVCEGGEL---- 112
Query: 187 ESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVY 246
FD I F E AVK++ I ++ G++HRDLKP+N L D
Sbjct: 113 ---FDRIVSKGHFS-------EREAVKLIKTILGVVEACHSLGVMHRDLKPENFLFDSPK 162
Query: 247 HS--LRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHAS 304
L+ +DFG S+ +K G+ L +VG+P + APE+ G
Sbjct: 163 DDAKLKATDFGLSVF------YKPGQY-------LYDVVGSPYYVAPEVLKKCYGP---- 205
Query: 305 NEQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQL 347
+IDVWS G+ +Y +L V PFW ETE + I +L
Sbjct: 206 -----EIDVWSAGVILYILLSGVPPFWAETESGIFRQILQGKL 243
>YCL024w [T] KOG0583 Serine/threonine protein kinase
Length = 1037
Score = 84.0 bits (206), Expect = 5e-16
Identities = 76/263 (28%), Positives = 119/263 (44%), Gaps = 55/263 (20%)
Query: 70 VNQYRIGERLGCGQFGTVY--KGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESIS 127
+ +++GE LG G G V + TG A+K I K N+ + S
Sbjct: 18 IGPWKLGETLGFGSTGKVQLAQHERTGHRTAVKVISKSIFNNNGNHS------------- 64
Query: 128 GDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRE 187
D ++ N+ + E + L+HPNV+ L + ++ ++ ++LI A GEL
Sbjct: 65 NDDSVLPYNIER---EIVIMKLLSHPNVLSLYDVWET--NNNLYLILEYAEKGEL----- 114
Query: 188 SKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYH 247
F+L+ G L E A+ I G+ Y GI+HRDLKP+N+LLD Y
Sbjct: 115 --FNLLVD-----HGPLPERE--AINCFRQIIIGISYCHALGIVHRDLKPENLLLDSFY- 164
Query: 248 SLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQ 307
+++I+DFG + + DL E G+P + APE+ + AS
Sbjct: 165 NIKIADFGMAALQTD---------ADLLETS----CGSPHYAAPEIVSGLPYEGFAS--- 208
Query: 308 PFKIDVWSLGITVYAILYNVLPF 330
DVWS G+ ++A+L LPF
Sbjct: 209 ----DVWSCGVILFALLTGRLPF 227
>Hs14777335 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 795
Score = 84.0 bits (206), Expect = 5e-16
Identities = 84/311 (27%), Positives = 136/311 (43%), Gaps = 65/311 (20%)
Query: 77 ERLGCGQFGTVYKGHTTGKVVAIKQIYKKPMNSPFSMSLI-MKTMKRYESISGDVLIMEM 135
E LG G+FG V++ +K P + +I +K+ K E + ++ IM
Sbjct: 495 EVLGGGRFGQVHR------------CTEKSTGLPLAAKIIKVKSAKDREDVKNEINIM-- 540
Query: 136 NVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESKFDLIEQ 195
++L+H N+IQL + +S +S L+ GEL FD I
Sbjct: 541 ------------NQLSHVNLIQLYDAFESKHS--CTLVMEYVDGGEL-------FDRITD 579
Query: 196 WKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNIL-LDPVYHSLRISDF 254
K ++ +LD V I G+ YL I+H DLKP+NIL ++ H ++I DF
Sbjct: 580 EK-YHLTELD-----VVLFTRQICEGVHYLHQHYILHLDLKPENILCVNQTGHQIKIIDF 633
Query: 255 GCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQPFKIDVW 314
G + + ++L GTP F APE+ N+ S F D+W
Sbjct: 634 GLARRYKPR-------------EKLKVNFGTPEFLAPEVVNYEFVS--------FPTDMW 672
Query: 315 SLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIYGWIHEYVVNRMLSKNT 374
S+G+ Y +L + PF GET+ +T N I + D + ++ V+R+L K
Sbjct: 673 SVGVITYMLLSGLSPFLGETDAETMNFIVNCSWDFDADTFEGLSEEAKDF-VSRLLVKEK 731
Query: 375 ASRPTTSNILR 385
+ R + + L+
Sbjct: 732 SCRMSATQCLK 742
>At2g41140 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 576
Score = 84.0 bits (206), Expect = 5e-16
Identities = 71/284 (25%), Positives = 119/284 (41%), Gaps = 67/284 (23%)
Query: 66 AQKFVNQYRIGERLGCGQFGTVY-----KGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTM 120
+++F + Y I +G G FG KG G+ VA+K I K M + ++ + + +
Sbjct: 116 SKQFASHYEIDGEVGRGHFGYTCSAKGKKGSLKGQEVAVKVIPKSKMTTAIAIEDVSREV 175
Query: 121 KRYESISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLG 180
K +++G H N++Q + + + ++++ L G
Sbjct: 176 KMLRALTG-----------------------HKNLVQFYDAFED--DENVYIVMELCKGG 210
Query: 181 ELQWSRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNI 240
EL D I Q Y E+ A KV+ I + + Y QG++HRDLKP+N
Sbjct: 211 EL-------LDKILQRGGKYS------EDDAKKVMVQILSVVAYCHLQGVVHRDLKPENF 257
Query: 241 LLDPVYHS--LRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAE 298
L + L+ DFG S V ++ LN IVG+ + APE+ +
Sbjct: 258 LFSTKDETSPLKAIDFGLSDYVKP-------------DERLNDIVGSAYYVAPEVLHRTY 304
Query: 299 GSAHASNEQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLI 342
G+ + D+WS+G+ Y +L PFW TE + +
Sbjct: 305 GT---------EADMWSIGVIAYILLCGSRPFWARTESGIFRAV 339
>Hs14670383 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 370
Score = 83.6 bits (205), Expect = 6e-16
Identities = 94/325 (28%), Positives = 138/325 (41%), Gaps = 66/325 (20%)
Query: 67 QKFVNQYRIGERLGCGQFGTVYKGH--TTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYE 124
QK + Y IGE LG GQF V K +TG A K I K+ + + + R E
Sbjct: 17 QKVEDFYDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRAS------RRGVSREE 70
Query: 125 SISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQW 184
+E VS +R ++ H NVI L + ++ + LI L GEL
Sbjct: 71 --------IEREVSILR-------QVLHHNVITLHDVYEN--RTDVVLILELVSGGEL-- 111
Query: 185 SRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILL-- 242
FD + Q +S EE A + I +G+ YL + I H DLKP+NI+L
Sbjct: 112 -----FDFLAQKESLS-------EEEATSFIKQILDGVNYLHTKKIAHFDLKPENIMLLD 159
Query: 243 --DPVYHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGS 300
P+ H +++ DFG + + + FK+ I GTP F APE+ N+
Sbjct: 160 KNIPIPH-IKLIDFGLAHEIEDGVEFKN-------------IFGTPEFVAPEIVNYEPLG 205
Query: 301 AHASNEQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIYGW 360
A D+WS+G+ Y +L PF G+T+ +T I D S
Sbjct: 206 LEA--------DMWSIGVITYILLSGASPFLGDTKQETLANITAVSYDFDEEFFSQTSEL 257
Query: 361 IHEYVVNRMLSKNTASRPTTSNILR 385
++ + ++L K T R T LR
Sbjct: 258 AKDF-IRKLLVKETRKRLTIQEALR 281
>At5g45810 [T] KOG0583 Serine/threonine protein kinase
Length = 483
Score = 83.6 bits (205), Expect = 6e-16
Identities = 77/283 (27%), Positives = 125/283 (43%), Gaps = 61/283 (21%)
Query: 62 QEEHAQKFVNQYRIGERLGCGQFGTVY--KGHTTGKVVAIKQIYKKPMNSPFSMSLIMKT 119
Q H + +Y +G LG G F VY + +G+ VAIK I K+ K
Sbjct: 17 QSNHQALILGKYEMGRLLGHGTFAKVYLARNAQSGESVAIKVIDKE------------KV 64
Query: 120 MKRYESISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVL 179
+K SG + ++ +S +R ++ HPN++QL E + + +I+ +
Sbjct: 65 LK-----SGLIAHIKREISILR-------RVRHPNIVQLFEVMAT--KSKIYFVMEYVKG 110
Query: 180 GELQWSRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQN 239
GEL + +G+L EE A K + + + + +G+ HRDLKP+N
Sbjct: 111 GEL-------------FNKVAKGRLK--EEMARKYFQQLISAVSFCHFRGVYHRDLKPEN 155
Query: 240 ILLDPVYHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEG 299
+LLD +L++SDFG S + S +DG LF + GTP + APE+
Sbjct: 156 LLLDE-NGNLKVSDFGLSAV--SDQIRQDG----LF----HTFCGTPAYVAPEV------ 198
Query: 300 SAHASNEQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLI 342
K+D+WS G+ ++ ++ LPF Y I
Sbjct: 199 -LARKGYDGAKVDIWSCGVILFVLMAGFLPFHDRNVMAMYKKI 240
>At1g74740 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 567
Score = 83.6 bits (205), Expect = 6e-16
Identities = 77/276 (27%), Positives = 118/276 (41%), Gaps = 67/276 (24%)
Query: 65 HAQKFVNQYRIGERLGCGQFGTVY--KGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKR 122
H + ++Y +G LG G+FG Y T + +A K I K+ + +
Sbjct: 51 HQSQISDKYILGRELGRGEFGITYLCTDRETREALACKSISKRKLRTA------------ 98
Query: 123 YESISGDVLIMEMNVSKIRWECFVTSKL-NHPNVIQLLECLDSPYSDQIWLIQPLAVLGE 181
++V +R E + S L HPNV++L + ++ + L+ L GE
Sbjct: 99 ------------VDVEDVRREVTIMSTLPEHPNVVKLKATYED--NENVHLVMELCEGGE 144
Query: 182 LQWSRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNIL 241
L FD I RG E A V I+ ++ G++HRDLKP+N L
Sbjct: 145 L-------FDRIVA-----RGHY--TERAAATVARTIAEVVRMCHVNGVMHRDLKPENFL 190
Query: 242 L--DPVYHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEG 299
+L+ DFG S++ FK G + +IVG+P + APE+ G
Sbjct: 191 FANKKENSALKAIDFGLSVL------FKPG-------ERFTEIVGSPYYMAPEVLKRNYG 237
Query: 300 SAHASNEQPFKIDVWSLGITVYAILYNVLPFWGETE 335
++DVWS G+ +Y +L V PFW ETE
Sbjct: 238 P---------EVDVWSAGVILYILLCGVPPFWAETE 264
>YGL180w [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 897
Score = 83.2 bits (204), Expect = 8e-16
Identities = 70/303 (23%), Positives = 131/303 (43%), Gaps = 80/303 (26%)
Query: 73 YRIGERLGCGQFGTVYKGHTTG---KVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISGD 129
Y + +G G F TVY+GH T + VAIK++ + + K K E++ +
Sbjct: 24 YTAEKEIGKGSFATVYRGHLTSDKSQHVAIKEVSRAKL----------KNKKLLENLEIE 73
Query: 130 VLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESK 189
+ I++ K+ HP+++ L++C + S +LI LG+L + + +
Sbjct: 74 IAILK--------------KIKHPHIVGLIDCERT--STDFYLIMEYCALGDLTFLLKRR 117
Query: 190 FDLIEQW---KSFYRGQLDSVEE-------FAVKVLGDISNGLQYLQGQGIIHRDLKPQN 239
+L+E ++ + E F + L +++ L++L+ + ++HRD+KPQN
Sbjct: 118 KELMENHPLLRTVFEKYPPPSENHNGLHRAFVLSYLQQLASALKFLRSKNLVHRDIKPQN 177
Query: 240 ILLDPV---YHS-----------------LRISDFGCSLIVPSKLPFKDGRLQDLFEKEL 279
+LL YH L+I+DFG + +P+
Sbjct: 178 LLLSTPLIGYHDSKSFHELGFVGIYNLPILKIADFGFARFLPN-------------TSLA 224
Query: 280 NKIVGTPLFTAPELCNFAEGSAHASNEQPFKIDVWSLGITVYAILYNVLPFWGETEFDTY 339
+ G+PL+ APE+ N+ + +A K D+WS+G V+ + PF + +
Sbjct: 225 ETLCGSPLYMAPEILNYQKYNA--------KADLWSVGTVVFEMCCGTPPFRASNHLELF 276
Query: 340 NLI 342
I
Sbjct: 277 KKI 279
>At5g45820 [T] KOG0583 Serine/threonine protein kinase
Length = 439
Score = 83.2 bits (204), Expect = 8e-16
Identities = 82/281 (29%), Positives = 118/281 (41%), Gaps = 61/281 (21%)
Query: 70 VNQYRIGERLGCGQFGTVYKGHT--TGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESIS 127
+ +Y +G LG G F VY TG+ VAIK I K+ + + LI
Sbjct: 9 MRKYELGRLLGQGTFAKVYHARNIKTGESVAIKVIDKQKVAK---VGLI----------- 54
Query: 128 GDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRE 187
+I+ E V + HP+V+ L E + S +I+ GEL
Sbjct: 55 ----------DQIKREISVMRLVRHPHVVFLHEVMAS--KTKIYFAMEYVKGGEL----- 97
Query: 188 SKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYH 247
FD + +G+L E A K + + Y +G+ HRDLKP+N+LLD
Sbjct: 98 --FDKVS------KGKLK--ENIARKYFQQLIGAIDYCHSRGVYHRDLKPENLLLDE-NG 146
Query: 248 SLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQ 307
L+ISDFG S + SK +DG L+ GTP + APE+
Sbjct: 147 DLKISDFGLSALRESKQ--QDGL--------LHTTCGTPAYVAPEVIG-------KKGYD 189
Query: 308 PFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLK 348
K DVWS G+ +Y +L LPF + + Y I + K
Sbjct: 190 GAKADVWSCGVVLYVLLAGFLPFHEQNLVEMYRKITKGEFK 230
>7304311 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 405
Score = 83.2 bits (204), Expect = 8e-16
Identities = 79/302 (26%), Positives = 130/302 (42%), Gaps = 68/302 (22%)
Query: 72 QYRIGERLGCGQFGTVYKGHTT---GKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISG 128
+Y + LG G F V + G+ A+K I KK + + ES+
Sbjct: 30 KYNLHGLLGTGAFSEVRLAESKDSPGEHFAVKIIDKKALKG------------KEESLEN 77
Query: 129 DVLIME-MNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRE 187
++ ++ + + +C ++L HPN++QLLE + +++L+ L GEL
Sbjct: 78 EIRVLRRFSANHFDGKCLNGTRLTHPNIVQLLETYED--KSKVYLVMELVTGGEL----- 130
Query: 188 SKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYH 247
FD I + S+ E+ A ++ I + Y+ QG++HRDLKP+N+L Y+
Sbjct: 131 --FDRIVEKGSY-------TEKDASHLIRQILEAVDYMHEQGVVHRDLKPENLL----YY 177
Query: 248 S------LRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSA 301
S + ISDFG S + S + + GTP + APE+
Sbjct: 178 SPDDDSKIMISDFGLSKMEDSGI--------------MATACGTPGYVAPEVL------- 216
Query: 302 HASNEQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIYGWI 361
A +DVWS+G+ Y +L PF+ E + + + I LK D S + I
Sbjct: 217 -AQKPYGKAVDVWSIGVISYILLCGYPPFYDENDANLFAQI----LKGDFEFDSPYWDEI 271
Query: 362 HE 363
E
Sbjct: 272 SE 273
>Hs9845489 [R] KOG0586 Serine/threonine protein kinase
Length = 691
Score = 82.8 bits (203), Expect = 1e-15
Identities = 84/321 (26%), Positives = 144/321 (44%), Gaps = 69/321 (21%)
Query: 67 QKFVNQYRIGERLGCGQFGTVYKGH--TTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYE 124
Q + YR+ + +G G F V TGK VA+K I K +NS S + K
Sbjct: 14 QPHIGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNS----SSLQK------ 63
Query: 125 SISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQW 184
L E+ + K+ LNHPN+++L E +++ + ++L+ A GE+
Sbjct: 64 ------LFREVRIMKV---------LNHPNIVKLFEVIETEKT--LYLVMEYASGGEV-- 104
Query: 185 SRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDP 244
FD + G++ E A I + +QY + I+HRDLK +N+LLD
Sbjct: 105 -----FDYLVA-----HGRMKEKEARAK--FRQIVSAVQYCHQKFIVHRDLKAENLLLD- 151
Query: 245 VYHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHAS 304
+++I+DFG S + F +L+ G+P + APEL +G +
Sbjct: 152 ADMNIKIADFGFS-------------NEFTFGNKLDTFCGSPPYAAPEL---FQGKKYDG 195
Query: 305 NEQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIYGWIHEY 364
E +DVWSLG+ +Y ++ LPF G+ + + + + + S++ E
Sbjct: 196 PE----VDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDC-----EN 246
Query: 365 VVNRMLSKNTASRPTTSNILR 385
++ + L N + R T I++
Sbjct: 247 LLKKFLILNPSKRGTLEQIMK 267
>Hs9845487 [R] KOG0586 Serine/threonine protein kinase
Length = 745
Score = 82.8 bits (203), Expect = 1e-15
Identities = 84/321 (26%), Positives = 144/321 (44%), Gaps = 69/321 (21%)
Query: 67 QKFVNQYRIGERLGCGQFGTVYKGH--TTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYE 124
Q + YR+ + +G G F V TGK VA+K I K +NS S + K
Sbjct: 14 QPHIGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNS----SSLQK------ 63
Query: 125 SISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQW 184
L E+ + K+ LNHPN+++L E +++ + ++L+ A GE+
Sbjct: 64 ------LFREVRIMKV---------LNHPNIVKLFEVIETEKT--LYLVMEYASGGEV-- 104
Query: 185 SRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDP 244
FD + G++ E A I + +QY + I+HRDLK +N+LLD
Sbjct: 105 -----FDYLVA-----HGRMKEKEARAK--FRQIVSAVQYCHQKFIVHRDLKAENLLLD- 151
Query: 245 VYHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHAS 304
+++I+DFG S + F +L+ G+P + APEL +G +
Sbjct: 152 ADMNIKIADFGFS-------------NEFTFGNKLDTFCGSPPYAAPEL---FQGKKYDG 195
Query: 305 NEQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIYGWIHEY 364
E +DVWSLG+ +Y ++ LPF G+ + + + + + S++ E
Sbjct: 196 PE----VDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDC-----EN 246
Query: 365 VVNRMLSKNTASRPTTSNILR 385
++ + L N + R T I++
Sbjct: 247 LLKKFLILNPSKRGTLEQIMK 267
>Hs22062450 [R] KOG0586 Serine/threonine protein kinase
Length = 787
Score = 82.8 bits (203), Expect = 1e-15
Identities = 84/321 (26%), Positives = 144/321 (44%), Gaps = 69/321 (21%)
Query: 67 QKFVNQYRIGERLGCGQFGTVYKGH--TTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYE 124
Q + YR+ + +G G F V TGK VA+K I K +NS S + K
Sbjct: 47 QPHIGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNS----SSLQK------ 96
Query: 125 SISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQW 184
L E+ + K+ LNHPN+++L E +++ + ++L+ A GE+
Sbjct: 97 ------LFREVRIMKV---------LNHPNIVKLFEVIETEKT--LYLVMEYASGGEV-- 137
Query: 185 SRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDP 244
FD + G++ E A I + +QY + I+HRDLK +N+LLD
Sbjct: 138 -----FDYLVA-----HGRMKEKEARAK--FRQIVSAVQYCHQKFIVHRDLKAENLLLD- 184
Query: 245 VYHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHAS 304
+++I+DFG S + F +L+ G+P + APEL +G +
Sbjct: 185 ADMNIKIADFGFS-------------NEFTFGNKLDTFCGSPPYAAPEL---FQGKKYDG 228
Query: 305 NEQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIYGWIHEY 364
E +DVWSLG+ +Y ++ LPF G+ + + + + + S++ E
Sbjct: 229 PE----VDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDC-----EN 279
Query: 365 VVNRMLSKNTASRPTTSNILR 385
++ + L N + R T I++
Sbjct: 280 LLKKFLILNPSKRGTLEQIMK 300
>At5g19450 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 533
Score = 82.8 bits (203), Expect = 1e-15
Identities = 77/267 (28%), Positives = 112/267 (41%), Gaps = 65/267 (24%)
Query: 73 YRIGERLGCGQFGTVY--KGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISGDV 130
Y +G +G G+FG Y TG+ A K I KK + +T E + +V
Sbjct: 57 YDLGREVGRGEFGITYLCTDIKTGEKYACKSISKKKL----------RTAVDIEDVRREV 106
Query: 131 LIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESKF 190
IM+ HPN++ L + + D + ++ L GEL F
Sbjct: 107 EIMK-------------HMPRHPNIVSLKDAFED--DDAVHIVMELCEGGEL-------F 144
Query: 191 DLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILL--DPVYHS 248
D I RG E A V+ I +Q G++HRDLKP+N L +
Sbjct: 145 DRIVA-----RGHY--TERAAAAVMKTILEVVQICHKHGVMHRDLKPENFLFANKKETSA 197
Query: 249 LRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQP 308
L+ DFG S+ FK G + N+IVG+P + APE+ G
Sbjct: 198 LKAIDFGLSVF------FKPG-------EGFNEIVGSPYYMAPEVLRRNYGP-------- 236
Query: 309 FKIDVWSLGITVYAILYNVLPFWGETE 335
++D+WS G+ +Y +L V PFW ETE
Sbjct: 237 -EVDIWSAGVILYILLCGVPPFWAETE 262
>At3g23000 [T] KOG0583 Serine/threonine protein kinase
Length = 429
Score = 82.8 bits (203), Expect = 1e-15
Identities = 83/326 (25%), Positives = 141/326 (42%), Gaps = 71/326 (21%)
Query: 66 AQKFVNQYRIGERLGCGQFGTVYKGHT--TGKVVAIKQIYKKPMNSPFSMSLIMKTMKRY 123
A+ + +Y +G RLG G F V+ + + ++VA+K I KK K
Sbjct: 18 AKILLGKYELGRRLGSGSFAKVHLARSIESDELVAVKIIEKK---------------KTI 62
Query: 124 ESISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQ 183
ES +I E++ + +HPN++++ E + + +I+L+ LA GEL
Sbjct: 63 ESGMEPRIIREIDAMR--------RLRHHPNILKIHEVMAT--KSKIYLVMELASGGEL- 111
Query: 184 WSRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLD 243
F K RG+L E A + +++ L++ G+ HRD+KPQN+LLD
Sbjct: 112 ------FS-----KVLRRGRLP--ESTARRYFQQLASALRFSHQDGVAHRDVKPQNLLLD 158
Query: 244 PVYHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHA 303
+L++SDFG S + + L L+ GTP +TAPE+ +
Sbjct: 159 E-QGNLKVSDFGLSALP-----------EHLQNGLLHTACGTPAYTAPEVIS-------R 199
Query: 304 SNEQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIYGWIHE 363
K D WS G+ ++ +L +PF Y I R + WI +
Sbjct: 200 RGYDGAKADAWSCGVILFVLLVGDVPFDDSNIAAMYRKIHRRDYR--------FPSWISK 251
Query: 364 Y---VVNRMLSKNTASRPTTSNILRT 386
++ +ML N +R + +++T
Sbjct: 252 QAKSIIYQMLDPNPVTRMSIETVMKT 277
>7298652 [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 459
Score = 82.8 bits (203), Expect = 1e-15
Identities = 77/320 (24%), Positives = 133/320 (41%), Gaps = 61/320 (19%)
Query: 73 YRIGERLGCGQFGTVYKGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISGDVLI 132
Y + +LG G +G V + +Y F+M ++ K M S +
Sbjct: 157 YYVNRKLGSGAYGLV------------RLVYDTRTCQQFAMKIVKKNMLSGARPSTNF-- 202
Query: 133 MEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESKFDL 192
+ ++ E + L+HP V+++ + +D P D ++++ G+L S L
Sbjct: 203 --SDPDRVLNEAKIMKNLSHPCVVRMHDIVDKP--DSVYMVLEFMRGGDLLNRIISNKLL 258
Query: 193 IEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYHS--LR 250
E Y Q+ + ++YL +GI HRDLKP N+LL+ L+
Sbjct: 259 SEDISKLYFYQM--------------CHAVKYLHDRGITHRDLKPDNVLLETNDEETLLK 304
Query: 251 ISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQPFK 310
+SDFG S V + + + GTPL+ APE+ A+ K
Sbjct: 305 VSDFGLSKFVQK-------------DSVMRTLCGTPLYVAPEVLITGGREAYTK-----K 346
Query: 311 IDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPD----VHNSSNIYGWIHEYVV 366
+D+WSLG+ ++ L LPF D Y +Q+K H S + ++
Sbjct: 347 VDIWSLGVVLFTCLSGTLPF-----SDEYGTPAAQQIKKGRFAYGHPSWKSVSQRAKLLI 401
Query: 367 NRMLSKNTASRPTTSNILRT 386
N+ML + RP+ ++L++
Sbjct: 402 NQMLIVDPERRPSIDDVLQS 421
>7290249 [R] KOG0586 Serine/threonine protein kinase
Length = 1398
Score = 82.8 bits (203), Expect = 1e-15
Identities = 71/252 (28%), Positives = 118/252 (46%), Gaps = 42/252 (16%)
Query: 134 EMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESKFDLI 193
+ N+ K+ E + +L HP++I+L + +++ + I+++ A GE+ FD I
Sbjct: 179 QTNLQKVYREVEIMKRLKHPHIIKLYQVMET--KNMIYIVSEYASQGEI-------FDYI 229
Query: 194 EQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYHSLRISD 253
+ Y +S F I + ++Y +GI+HRDLK +N+LLD + +++I+D
Sbjct: 230 AK----YGRMSESAARFK---FWQIISAVEYCHKKGIVHRDLKAENLLLD-LNMNIKIAD 281
Query: 254 FGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQPFKIDV 313
FG S FK G L L G+P + APE+ EG + E ID+
Sbjct: 282 FGFS------NHFKPGEL-------LATWCGSPPYAAPEV---FEGKQYTGPE----IDI 321
Query: 314 WSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIYGWIHEYVVNRMLSKN 373
WSLG+ +Y ++ LPF G T + + + + SS E+++ RML
Sbjct: 322 WSLGVVLYVLVCGALPFDGSTLQSLRDRVLSGRFRIPFFMSSEC-----EHLIRRMLVLE 376
Query: 374 TASRPTTSNILR 385
R T I R
Sbjct: 377 PTRRYTIDQIKR 388
>SPCC1259.13 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 496
Score = 82.4 bits (202), Expect = 1e-15
Identities = 81/291 (27%), Positives = 127/291 (42%), Gaps = 60/291 (20%)
Query: 66 AQKFVN-QYRIGERLGCGQFGTVYKGHT-TGKVVAIKQIYKKPMNSPFSMSLIMKTMKRY 123
AQK N Y IG +G G F +V + K+ A+K + KK S + + + M
Sbjct: 2 AQKLDNFPYHIGREIGTGAFASVRLCYDDNAKIYAVKFVNKKHATSCMNAGVWARRMAS- 60
Query: 124 ESISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQ 183
E+ + K+ C H N+I ++P W++ A G+L
Sbjct: 61 ----------EIQLHKL---CN-----GHKNIIHFYNTAENP--QWRWVVLEFAQGGDLF 100
Query: 184 WSRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLD 243
E + E FY QL G+ ++ +G+ HRDLKP+NILLD
Sbjct: 101 DKIEPDVGIDEDVAQFYFAQL--------------MEGISFMHSKGVAHRDLKPENILLD 146
Query: 244 PVYHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHA 303
+L+ISDFG + + K G+ + LN VG+P + APE+ +GS
Sbjct: 147 -YNGNLKISDFGFASLFSYK-----GK-----SRLLNSPVGSPPYAAPEITQQYDGS--- 192
Query: 304 SNEQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQL--KPDVH 352
K+DVWS GI ++A+L P W E +T + + +++ +P H
Sbjct: 193 ------KVDVWSCGIILFALLLGNTP-WDEAISNTGDYLLYKKQCERPSYH 236
>CE24761 [D] KOG0580 Serine/threonine protein kinase
Length = 305
Score = 82.4 bits (202), Expect = 1e-15
Identities = 78/277 (28%), Positives = 120/277 (43%), Gaps = 69/277 (24%)
Query: 70 VNQYRIGERLGCGQFGTVYKGHT-TGKV-VAIKQIYKKPMNSPFSMSLIMKTMKRYESIS 127
+N + IG LG G+FG+VY T TG VAIK ++K + IS
Sbjct: 27 INDFEIGRPLGKGKFGSVYLARTKTGHFHVAIKVLFKSQL------------------IS 68
Query: 128 GDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGEL--QWS 185
G V ++ E + S LNHPN+I+L + +I+L+ A GE+ Q +
Sbjct: 69 GGV------EHQLEREIEIQSHLNHPNIIKLYTYFWD--AKKIYLVLEYAPGGEMYKQLT 120
Query: 186 RESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPV 245
+F E A K + +I++ L Y + +IHRD+KP+N+L+
Sbjct: 121 VSKRFS----------------EPTAAKYMYEIADALSYCHRKNVIHRDIKPENLLIGS- 163
Query: 246 YHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASN 305
L+I DFG S+ PS + + GT + PE+ N A+ S
Sbjct: 164 QGELKIGDFGWSVHAPS--------------NKRQTMCGTMDYLPPEMVNGADHSD---- 205
Query: 306 EQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLI 342
+D+W++G+ Y L PF E + TY I
Sbjct: 206 ----AVDLWAIGVLCYEFLVGKPPFEHEDQSKTYAAI 238
>At2g26980 [T] KOG0583 Serine/threonine protein kinase
Length = 441
Score = 82.4 bits (202), Expect = 1e-15
Identities = 86/327 (26%), Positives = 138/327 (41%), Gaps = 71/327 (21%)
Query: 62 QEEHAQKFVNQYRIGERLGCGQFGTVY--KGHTTGKVVAIKQIYKKPMNSPFSMSLIMKT 119
+ + ++ V +Y +G +G G F V + TG+ VA+K + K+ +
Sbjct: 3 RRQQVKRRVGKYEVGRTIGEGTFAKVKFARNSETGEPVALKILDKEKV------------ 50
Query: 120 MKRYESISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVL 179
+ +IR E + HPNV+QL E + S +I++I
Sbjct: 51 ------------LKHKMAEQIRREIATMKLIKHPNVVQLYEVMAS--KTKIFIILEYVTG 96
Query: 180 GELQWSRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQN 239
GEL FD I G++ E+ A + + + + Y +G+ HRDLKP+N
Sbjct: 97 GEL-------FDKIVN-----DGRMK--EDEARRYFQQLIHAVDYCHSRGVYHRDLKPEN 142
Query: 240 ILLDPVYHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEG 299
+LLD Y +L+ISDFG S + S+ DG L+ GTP + APE+ N G
Sbjct: 143 LLLDS-YGNLKISDFGLSAL--SQQVRDDGL--------LHTSCGTPNYVAPEVLN-DRG 190
Query: 300 SAHASNEQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIYG 359
A+ D+WS G+ +Y +L LPF + Y I + N
Sbjct: 191 YDGAT------ADMWSCGVVLYVLLAGYLPFDDSNLMNLYKKISSGEF--------NCPP 236
Query: 360 WIH---EYVVNRMLSKNTASRPTTSNI 383
W+ ++ R+L N +R T +
Sbjct: 237 WLSLGAMKLITRILDPNPMTRVTPQEV 263
>At1g62400 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 345
Score = 82.4 bits (202), Expect = 1e-15
Identities = 76/323 (23%), Positives = 139/323 (42%), Gaps = 64/323 (19%)
Query: 70 VNQYRIGERLGCGQFGTVYKGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISGD 129
++Q IG + G +Y+G + VA+K + + P + + + + + K
Sbjct: 38 LSQLFIGNKFASGAHSRIYRGIYKQRAVAVKMV-RIPTHKEETRAKLEQQFKS------- 89
Query: 130 VLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESK 189
E + S+L HPN++Q + P P+ + ++ +
Sbjct: 90 -------------EVALLSRLFHPNIVQFIAACKKP---------PVYCI-ITEYMSQGN 126
Query: 190 FDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYHSL 249
+ K Y +++V A+ DIS G++YL QG+IHRDLK N+LL+ +
Sbjct: 127 LRMYLNKKEPYSLSIETVLRLAL----DISRGMEYLHSQGVIHRDLKSNNLLLNDEMR-V 181
Query: 250 RISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQPF 309
+++DFG S + + +E +GT + APE+ E+P+
Sbjct: 182 KVADFGTSCL-------------ETQCREAKGNMGTYRWMAPEMI----------KEKPY 218
Query: 310 --KIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIYGWIHEYVVN 367
K+DV+S GI ++ + +LPF G T + + +P + S +++
Sbjct: 219 TRKVDVYSFGIVLWELTTALLPFQGMTPVQAAFAVAEKNERPPLPASCQP---ALAHLIK 275
Query: 368 RMLSKNTASRPTTSNILRTLESH 390
R S+N + RP SNI+ LE +
Sbjct: 276 RCWSENPSKRPDFSNIVAVLEKY 298
>Hs4507275 [D] KOG0580 Serine/threonine protein kinase
Length = 403
Score = 82.0 bits (201), Expect = 2e-15
Identities = 81/326 (24%), Positives = 132/326 (39%), Gaps = 72/326 (22%)
Query: 62 QEEHAQKFVNQYRIGERLGCGQFGTVYKGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMK 121
+ + Q + + IG LG G+FG VY + S F ++L +
Sbjct: 122 ESKKRQWALEDFEIGRPLGKGKFGNVYLA--------------REKQSKFILALKVLFKA 167
Query: 122 RYESISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGE 181
+ E + ++R E + S L HPN+++L + +++LI A LG
Sbjct: 168 QLEKAGVE--------HQLRREVEIQSHLRHPNILRLYGYFHD--ATRVYLILEYAPLGT 217
Query: 182 L--QWSRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQN 239
+ + + SKFD E+ + +++N L Y + +IHRD+KP+N
Sbjct: 218 VYRELQKLSKFD----------------EQRTATYITELANALSYCHSKRVIHRDIKPEN 261
Query: 240 ILLDPVYHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEG 299
+LL L+I+DFG S+ PS + GT + PE+ EG
Sbjct: 262 LLLGSA-GELKIADFGWSVHAPS--------------SRRTTLCGTLDYLPPEM---IEG 303
Query: 300 SAHASNEQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLK-PDVHNSSNIY 358
H K+D+WSLG+ Y L PF T +TY I + PD
Sbjct: 304 RMHDE-----KVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEG--- 355
Query: 359 GWIHEYVVNRMLSKNTASRPTTSNIL 384
+++R+L N + RP +L
Sbjct: 356 ---ARDLISRLLKHNPSQRPMLREVL 378
>At1g30270 [T] KOG0583 Serine/threonine protein kinase
Length = 480
Score = 82.0 bits (201), Expect = 2e-15
Identities = 83/317 (26%), Positives = 133/317 (41%), Gaps = 67/317 (21%)
Query: 70 VNQYRIGERLGCGQFGTVY--KGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESIS 127
V +Y +G LG G F V + G VAIK I K+ +
Sbjct: 28 VGKYELGRTLGEGTFAKVKFARNVENGDNVAIKVIDKEKV-------------------- 67
Query: 128 GDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRE 187
+ +++I+ E + HPNVI++ E + S +I+ + GEL
Sbjct: 68 ----LKNKMIAQIKREISTMKLIKHPNVIRMFEVMAS--KTKIYFVLEFVTGGEL----- 116
Query: 188 SKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYH 247
FD I G+L E+ A K + N + Y +G+ HRDLKP+N+LLD
Sbjct: 117 --FDKISS-----NGRLK--EDEARKYFQQLINAVDYCHSRGVYHRDLKPENLLLD-ANG 166
Query: 248 SLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQ 307
+L++SDFG S LP ++ L L+ GTP + APE+ N
Sbjct: 167 ALKVSDFGL-----SALPQQEDGL-------LHTTCGTPNYVAPEVIN-------NKGYD 207
Query: 308 PFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIYGWIHEYVVN 367
K D+WS G+ ++ ++ LPF Y I + S++ + ++
Sbjct: 208 GAKADLWSCGVILFVLMAGYLPFEDSNLTSLYKKIFKAEFTCPPWFSASA-----KKLIK 262
Query: 368 RMLSKNTASRPTTSNIL 384
R+L N A+R T + ++
Sbjct: 263 RILDPNPATRITFAEVI 279
>7290150 [T] KOG0583 Serine/threonine protein kinase
Length = 582
Score = 82.0 bits (201), Expect = 2e-15
Identities = 78/261 (29%), Positives = 118/261 (44%), Gaps = 59/261 (22%)
Query: 70 VNQYRIGERLGCGQFGTVYKGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISGD 129
+ Y +G LG G FG V G ++ +K + +K + R + S D
Sbjct: 25 IGHYLLGATLGTGTFGKVKIGEH--QITRVK--------------VAVKILNRQKIKSLD 68
Query: 130 VLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESK 189
V V KIR E HP++I+L + + +P I++I GEL
Sbjct: 69 V------VGKIRREIQNLKLFRHPHIIKLYQVISTP--SDIFMIMEYVSGGEL------- 113
Query: 190 FDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYHSL 249
FD I + G+L E A + I +G+ Y I+HRDLKP+N+LLD H +
Sbjct: 114 FDYIVK-----HGKLQ--EHQARRFFQQIISGVDYCHRHMIVHRDLKPENLLLDHNMH-V 165
Query: 250 RISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQPF 309
+I+DFG S ++ DG L G+P + APE+ + G +A E
Sbjct: 166 KIADFGLSNMM------LDGEF-------LRTSCGSPNYAAPEVIS---GKLYAGPE--- 206
Query: 310 KIDVWSLGITVYAILYNVLPF 330
+D+WS G+ +YA+L LPF
Sbjct: 207 -VDIWSCGVILYALLCGTLPF 226
>7289880 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kinase beta
and related serine/threonine protein kinases
Length = 338
Score = 82.0 bits (201), Expect = 2e-15
Identities = 71/248 (28%), Positives = 111/248 (44%), Gaps = 44/248 (17%)
Query: 137 VSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGE-LQWSRESKFDLIEQ 195
+ ++ E V KL+HPNV++L+E LD P D ++++ L GE L+ ++
Sbjct: 27 LDRVYREIAVLKKLDHPNVVKLVEVLDDPLEDSLYMVFELVKQGEVLRIPTDNPLSEKRA 86
Query: 196 WKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYHSLRISDFG 255
W F L GL+YL Q IIH D+KP N+LL H ++I+D G
Sbjct: 87 WSIFRESLL----------------GLEYLHHQKIIHADIKPGNLLLTEFGH-VKIADLG 129
Query: 256 -CSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQPFK-IDV 313
C+ + +G GTP F APE NE + DV
Sbjct: 130 VCNEFLGDDATISNG-----------STAGTPAFRAPETL------IPGQNEYCGRAADV 172
Query: 314 WSLGITVYAILYNVLPFWGETEFDTYNLICHRQLK-PDVHN-SSNIYGWIHEYVVNRMLS 371
W+LG T+Y++++ +PF ++ Y I +K P+ H + N+ + + +ML
Sbjct: 173 WALGATLYSLIFGNVPFLADSVPLLYEKIKQDSVKFPENHKVTENL-----KSCIVQMLE 227
Query: 372 KNTASRPT 379
KN R T
Sbjct: 228 KNPTQRIT 235
>HsM4507279 [D] KOG0580 Serine/threonine protein kinase
Length = 402
Score = 81.6 bits (200), Expect = 2e-15
Identities = 81/318 (25%), Positives = 128/318 (39%), Gaps = 72/318 (22%)
Query: 70 VNQYRIGERLGCGQFGTVYKGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISGD 129
+ + IG LG G+FG VY + S F ++L + + E +
Sbjct: 129 LEDFEIGRPLGKGKFGNVYLA--------------REKQSKFILALKVLFKAQLEKAGVE 174
Query: 130 VLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGEL--QWSRE 187
++R E + S L HPN+++L + +++LI A LG + + +
Sbjct: 175 --------HQLRREVEIQSHLRHPNILRLYGYFHD--ATRVYLILEYAPLGTVYRELQKL 224
Query: 188 SKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYH 247
SKFD E+ + I+N L Y + +IHRD+KP+N+LL
Sbjct: 225 SKFD----------------EQRTANLYNRIANALSYCHSKRVIHRDIKPENLLLGSA-G 267
Query: 248 SLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQ 307
L+I+DFG S+ PS + GT + PE+ EG H
Sbjct: 268 ELKIADFGWSVHAPS--------------SRRTTLCGTLDYLPPEM---IEGRMHDE--- 307
Query: 308 PFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLK-PDVHNSSNIYGWIHEYVV 366
K+D+WSLG+ Y L PF T +TY I + PD ++
Sbjct: 308 --KVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEG------ARDLI 359
Query: 367 NRMLSKNTASRPTTSNIL 384
+R+L N + RP +L
Sbjct: 360 SRLLKHNPSQRPMLREVL 377
>At3g50530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 601
Score = 81.6 bits (200), Expect = 2e-15
Identities = 79/329 (24%), Positives = 134/329 (40%), Gaps = 74/329 (22%)
Query: 66 AQKFVNQYRIGERLGCGQFGTVY-----KGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTM 120
++ F ++Y +G+ +G G FG KG G+ VA+K I K M + ++ + + +
Sbjct: 141 SKSFASKYELGDEVGRGHFGYTCAAKFKKGDNKGQQVAVKVIPKAKMTTAIAIEDVRREV 200
Query: 121 KRYESISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLG 180
K ++SG H N+ + + D ++++ L G
Sbjct: 201 KILRALSG-----------------------HNNLPHFYDAYED--HDNVYIVMELCEGG 235
Query: 181 ELQ---WSRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKP 237
EL SR K+ EE A V+ I N + + QG++HRDLKP
Sbjct: 236 ELLDRILSRGGKY----------------TEEDAKTVMIQILNVVAFCHLQGVVHRDLKP 279
Query: 238 QNILLDPVYHS--LRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCN 295
+N L + L+ DFG S V ++ LN IVG+ + APE+ +
Sbjct: 280 ENFLFTSKEDTSQLKAIDFGLSDYVRP-------------DERLNDIVGSAYYVAPEVLH 326
Query: 296 FAEGSAHASNEQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSS 355
+ + + D+WS+G+ VY +L PFW TE + + D
Sbjct: 327 RSYST---------EADIWSVGVIVYILLCGSRPFWARTESGIFRAVLKADPSFDDPPWP 377
Query: 356 NIYGWIHEYVVNRMLSKNTASRPTTSNIL 384
+ ++ V R+L+K+ R T + L
Sbjct: 378 LLSSEARDF-VKRLLNKDPRKRLTAAQAL 405
>At2g45490 [D] KOG0580 Serine/threonine protein kinase
Length = 288
Score = 81.6 bits (200), Expect = 2e-15
Identities = 80/319 (25%), Positives = 138/319 (43%), Gaps = 77/319 (24%)
Query: 73 YRIGERLGCGQFGTVYKGHTTGK--VVAIKQIYKKPMNSPFSMSLIMKTMKRYESISGDV 130
+ IG LG G+FG VY +VA+K I+K+ + ++Y+
Sbjct: 22 FEIGRPLGKGKFGRVYLAREAKSKYIVALKVIFKEQI-------------EKYKIHH--- 65
Query: 131 LIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESKF 190
++R E + + L HPN+++L +++I+LI A GEL +
Sbjct: 66 --------QLRREMEIQTSLRHPNILRLFGWFHD--NERIFLILEYAHGGELYGVLKQNG 115
Query: 191 DLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYHSLR 250
L EQ + Y + +S L Y G+ +IHRD+KP+N+LLD L+
Sbjct: 116 HLTEQQAATY--------------IASLSQALAYCHGKCVIHRDIKPENLLLDH-EGRLK 160
Query: 251 ISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQPFK 310
I+DFG S+ +K + GT + APE+ + + +
Sbjct: 161 IADFGWSVQSSNK---------------RKTMCGTLDYLAPEMVE--------NRDHDYA 197
Query: 311 IDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLK----PDVHNSSNIYGWIHEYVV 366
+D W+LGI Y LY PF E++ DT+ I L P+V + + ++
Sbjct: 198 VDNWTLGILCYEFLYGNPPFEAESQKDTFKRILKIDLSFPLTPNVSEEA-------KNLI 250
Query: 367 NRMLSKNTASRPTTSNILR 385
+++L K+ + R + I++
Sbjct: 251 SQLLVKDPSKRLSIEKIMQ 269
>At1g01140 [T] KOG0583 Serine/threonine protein kinase
Length = 447
Score = 81.6 bits (200), Expect = 2e-15
Identities = 85/317 (26%), Positives = 135/317 (41%), Gaps = 65/317 (20%)
Query: 70 VNQYRIGERLGCGQFGTVY--KGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESIS 127
V Y +G LG G F V K TG AIK I+ K +
Sbjct: 16 VGNYEMGRTLGEGSFAKVKYAKNTVTGDQAAIK---------------ILDREKVFRHKM 60
Query: 128 GDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRE 187
+ L E++ K+ + HPNV++++E + S +I+++ L GEL
Sbjct: 61 VEQLKREISTMKL---------IKHPNVVEIIEVMAS--KTKIYIVLELVNGGEL----- 104
Query: 188 SKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYH 247
FD I Q +G+L E+ A + + N + Y +G+ HRDLKP+N++LD
Sbjct: 105 --FDKIAQ-----QGRLK--EDEARRYFQQLINAVDYCHSRGVYHRDLKPENLILD-ANG 154
Query: 248 SLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQ 307
L++SDFG S S+ +DG L+ GTP + APE+ + A+
Sbjct: 155 VLKVSDFGLSAF--SRQVREDGL--------LHTACGTPNYVAPEVLSDKGYDGAAA--- 201
Query: 308 PFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIYGWIHEYVVN 367
DVWS G+ ++ ++ LPF Y IC + S + V+
Sbjct: 202 ----DVWSCGVILFVLMAGYLPFDEPNLMTLYKRICKAEFSCPPWFSQGA-----KRVIK 252
Query: 368 RMLSKNTASRPTTSNIL 384
R+L N +R + + +L
Sbjct: 253 RILEPNPITRISIAELL 269
>Hs5453966 [T] KOG0583 Serine/threonine protein kinase
Length = 552
Score = 81.3 bits (199), Expect = 3e-15
Identities = 75/271 (27%), Positives = 124/271 (45%), Gaps = 63/271 (23%)
Query: 62 QEEHAQKFVNQYRIGERLGCGQFGTVYKGH--TTGKVVAIKQIYKKPMNSPFSMSLIMKT 119
Q+ + + Y +G+ LG G FG V G TG VA+K + ++ + S
Sbjct: 5 QKHDGRVKIGHYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSL--------- 55
Query: 120 MKRYESISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVL 179
DV V KI+ E HP++I+L + + +P +++
Sbjct: 56 ---------DV------VGKIKREIQNLKLFRHPHIIKLYQVISTP--TDFFMVMEYVSG 98
Query: 180 GELQWSRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQN 239
GEL FD I + G+++ +E A ++ I + + Y ++HRDLKP+N
Sbjct: 99 GEL-------FDYICK-----HGRVEEME--ARRLFQQILSAVDYCHRHMVVHRDLKPEN 144
Query: 240 ILLDPVYHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEG 299
+LLD + + +I+DFG S ++ DG L G+P +TAPE+ + G
Sbjct: 145 VLLD-AHMNAKIADFGLSNMM------SDGEF-------LRTSCGSPNYTAPEVIS---G 187
Query: 300 SAHASNEQPFKIDVWSLGITVYAILYNVLPF 330
+A E +D+WS G+ +YA+L LPF
Sbjct: 188 RLYAGPE----VDIWSCGVILYALLCGTLPF 214
>CE05780 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 336
Score = 81.3 bits (199), Expect = 3e-15
Identities = 75/322 (23%), Positives = 141/322 (43%), Gaps = 56/322 (17%)
Query: 67 QKFVNQYRIGERLGCGQFGTVY--KGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYE 124
Q QY IG +G G F +V+ + G A+K Y+ + F + KR
Sbjct: 51 QDIEKQYEIGAIIGKGNFSSVHLTRRKEDGTKCALKVRYQSTLQFSFPSKFFQQVEKR-- 108
Query: 125 SISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQW 184
++ G ++ V + S + H ++I +++ + +Q +++ A G+L
Sbjct: 109 AMRGKCFFVDNEVEML-------SLIQHDHIISIIDAFST--ENQYFIVFEHAQYGDL-- 157
Query: 185 SRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDP 244
++ I + G+++ E A + +++ L YL + ++HRD+KP+N+LL
Sbjct: 158 -----YETIRK-----NGRIE--EPDAAIITLQVASALNYLHERNVVHRDVKPENLLLVD 205
Query: 245 VYHSLRISDFG--CSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAH 302
+ S+++ DFG C ++ P L +I GTP + APE+ S
Sbjct: 206 KF-SVKLCDFGLACHILGP-----------------LYRICGTPTYCAPEVLRETGYST- 246
Query: 303 ASNEQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIYGWIH 362
+ D+WSLG+ +Y +L PF + + LI + D+ I
Sbjct: 247 -------RCDIWSLGVVLYVMLVGYAPFRAPDQTRLFKLIMQAKPNLDMPEWKGI-SLKA 298
Query: 363 EYVVNRMLSKNTASRPTTSNIL 384
+ +V+R+++K RP S I+
Sbjct: 299 KDLVSRLMNKTEERRPLASQIM 320
>At4g04740 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 520
Score = 81.3 bits (199), Expect = 3e-15
Identities = 83/331 (25%), Positives = 135/331 (40%), Gaps = 81/331 (24%)
Query: 64 EHAQKFVNQYRIGERLGCGQFGTVY--KGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMK 121
E +KF Y +G LG G G Y K TG + A K I K+ + S + ++
Sbjct: 63 EDIRKF---YSLGRELGRGGLGITYMCKEIGTGNIYACKSILKRKLISELGREDVKTEIQ 119
Query: 122 RYESISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGE 181
+ +SG PNV+++ + +S + L+ L GE
Sbjct: 120 IMQHLSGQ-----------------------PNVVEIKGSYEDRHS--VHLVMELCAGGE 154
Query: 182 LQWSRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNIL 241
L FD I Q E A + I + +Q G+IHRDLKP+N L
Sbjct: 155 L-------FDRII-------AQGHYSERAAAGTIKSIVDVVQICHLNGVIHRDLKPENFL 200
Query: 242 LDPVYHS--LRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEG 299
+ L+++DFG S + +KD +VG+P + APE+ + G
Sbjct: 201 FSSKEENAMLKVTDFGLSAFIEEGKIYKD-------------VVGSPYYVAPEVLRQSYG 247
Query: 300 SAHASNEQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICH------RQLKPDVHN 353
+ID+WS G+ +Y +L V PFW + E + I R+ P + +
Sbjct: 248 K---------EIDIWSAGVILYILLCGVPPFWADNEEGVFVEILKCKIDFVREPWPSISD 298
Query: 354 SSNIYGWIHEYVVNRMLSKNTASRPTTSNIL 384
S+ + +V +ML+++ R T + +L
Sbjct: 299 SA-------KDLVEKMLTEDPKRRITAAQVL 322
>At2g37840 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 257
Score = 81.3 bits (199), Expect = 3e-15
Identities = 72/273 (26%), Positives = 118/273 (42%), Gaps = 68/273 (24%)
Query: 68 KFVNQYRIGERLGCGQFGTVYKGH--TTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYES 125
+ V Y +G ++G G F V++ G VAIK+I +N SL+
Sbjct: 7 RVVGDYLVGRQIGSGSFSVVWEARHRVDGTEVAIKEIAMDRLNKKLQESLMS-------- 58
Query: 126 ISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWS 185
E F+ ++NHPN+I+L++ + SP ++ L+ G+L
Sbjct: 59 -----------------EIFILRRINHPNIIRLIDMIKSP--GKVHLVLEYCKGGDL--- 96
Query: 186 RESKFDLIEQWKSFYRGQLDSVEEFAVK-VLGDISNGLQYLQGQGIIHRDLKPQNILLDP 244
S Y + V E K + ++ GLQ L+ IIHRDLKPQN+LL
Sbjct: 97 ------------SVYVQRHGIVPEATAKHFMQQLAAGLQVLRDNNIIHRDLKPQNLLLST 144
Query: 245 VYH--SLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAH 302
+ L+I+DFG + + + G + L G+PL+ APE+ + A
Sbjct: 145 NENDADLKIADFGFARSLQPR-----GLAETL--------CGSPLYMAPEIMQLQKYDA- 190
Query: 303 ASNEQPFKIDVWSLGITVYAILYNVLPFWGETE 335
K D+WS+G ++ ++ PF G ++
Sbjct: 191 -------KADLWSVGAILFQLVTGRTPFTGNSQ 216
>At2g24360 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 407
Score = 81.3 bits (199), Expect = 3e-15
Identities = 78/321 (24%), Positives = 139/321 (43%), Gaps = 62/321 (19%)
Query: 70 VNQYRIGERLGCGQFGTVYKGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISGD 129
+ + +G G FG +YKG G+ VAIK I ++P NSP + + ++
Sbjct: 123 LRKLNMGPAFAQGAFGKLYKGTYNGEDVAIK-ILERPENSPEKAQFMEQQFQQ------- 174
Query: 130 VLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESK 189
E + + L HPN+++ + P +W I + +K
Sbjct: 175 -------------EVSMLANLKHPNIVRFIGACRKP---MVWCIV----------TEYAK 208
Query: 190 FDLIEQWKSFYRGQLDSVE-EFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYHS 248
+ Q+ + R Q +V + AVK D++ G+ Y+ G+ IHRDLK N+L+ S
Sbjct: 209 GGSVRQFLT--RRQNRAVPLKLAVKQALDVARGMAYVHGRNFIHRDLKSDNLLIS-ADKS 265
Query: 249 LRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQP 308
++I+DFG + I ++ + + GT + APE+ H + Q
Sbjct: 266 IKIADFGVARI-------------EVQTEGMTPETGTYRWMAPEMIQ------HRAYNQ- 305
Query: 309 FKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIYGWIHEYVVNR 368
K+DV+S GI ++ ++ +LPF T + +R ++P V N + ++ R
Sbjct: 306 -KVDVYSFGIVLWELITGLLPFQNMTAVQAAFAVVNRGVRPTVPNDCLP---VLSDIMTR 361
Query: 369 MLSKNTASRPTTSNILRTLES 389
N RP +++ LE+
Sbjct: 362 CWDANPEVRPCFVEVVKLLEA 382
>At1g61950 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 547
Score = 81.3 bits (199), Expect = 3e-15
Identities = 85/321 (26%), Positives = 136/321 (41%), Gaps = 73/321 (22%)
Query: 72 QYRIGERLGCGQFGTVY--KGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISGD 129
+Y +G LG GQFG Y ++GK A K I K+ + ++T R E + +
Sbjct: 97 KYSLGRELGRGQFGITYICTEISSGKNFACKSILKRKL---------IRTKDR-EDVRRE 146
Query: 130 VLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESK 189
+ IM + PN++++ + S + L+ L GEL
Sbjct: 147 IQIMHYLSGQ-------------PNIVEIKGAYEDRQS--VHLVMELCEGGEL------- 184
Query: 190 FDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILL---DPVY 246
FD I + RG E+ A +++ + +Q G+IHRDLKP+N LL D
Sbjct: 185 FDKITK-----RGHYS--EKAAAEIIRSVVKVVQICHFMGVIHRDLKPENFLLSSKDEAS 237
Query: 247 HSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNE 306
L+ +DFG S+ + ++D IVG+ + APE+ G A
Sbjct: 238 SMLKATDFGVSVFIEEGKVYED-------------IVGSAYYVAPEVLKRNYGKA----- 279
Query: 307 QPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIYGWIHEY-- 364
ID+WS G+ +Y +L PFW ET+ + I L+ ++ S + I E
Sbjct: 280 ----IDIWSAGVILYILLCGNPPFWAETDKGIFEEI----LRGEIDFESEPWPSISESAK 331
Query: 365 -VVNRMLSKNTASRPTTSNIL 384
+V ML + R T + +L
Sbjct: 332 DLVRNMLKYDPKKRFTAAQVL 352
>At5g35410 [T] KOG0583 Serine/threonine protein kinase
Length = 446
Score = 80.9 bits (198), Expect = 4e-15
Identities = 86/312 (27%), Positives = 141/312 (44%), Gaps = 71/312 (22%)
Query: 70 VNQYRIGERLGCGQFGTVY--KGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESIS 127
V +Y +G +G G F V + TG VAIK + K S I+K
Sbjct: 8 VGKYEVGRTIGEGTFAKVKFARNTDTGDNVAIKIMAK---------STILKNRM------ 52
Query: 128 GDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRE 187
V +I+ E + + HPN+++L E L SP +I+++ GEL
Sbjct: 53 ---------VDQIKREISIMKIVRHPNIVRLYEVLASP--SKIYIVLEFVTGGEL----- 96
Query: 188 SKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYH 247
FD I ++G+L+ E + K + + + + +G+ HRDLKP+N+LLD
Sbjct: 97 --FDRI-----VHKGRLEESE--SRKYFQQLVDAVAHCHCKGVYHRDLKPENLLLD-TNG 146
Query: 248 SLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFA--EGSAHASN 305
+L++SDFG S LP + L L GTP + APE+ + +GSA
Sbjct: 147 NLKVSDFGL-----SALPQEGVEL-------LRTTCGTPNYVAPEVLSGQGYDGSA---- 190
Query: 306 EQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIYGWIHEYV 365
D+WS G+ ++ IL LPF +E D L +R++ + + +++
Sbjct: 191 -----ADIWSCGVILFVILAGYLPF---SETDLPGL--YRKINAAEFSCPPWFSAEVKFL 240
Query: 366 VNRMLSKNTASR 377
++R+L N +R
Sbjct: 241 IHRILDPNPKTR 252
>At4g24400 [T] KOG0583 Serine/threonine protein kinase
Length = 445
Score = 80.9 bits (198), Expect = 4e-15
Identities = 82/314 (26%), Positives = 133/314 (42%), Gaps = 63/314 (20%)
Query: 70 VNQYRIGERLGCGQFGTVYKGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISGD 129
V +Y +G +G G F V K N+ S+ MK + R
Sbjct: 6 VGKYELGRTIGEGTFAKV----------------KFAQNTETGESVAMKIVDR------S 43
Query: 130 VLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESK 189
+I V +I+ E + + HP V++L E L S +I++I GEL
Sbjct: 44 TIIKRKMVDQIKREISIMKLVRHPCVVRLYEVLAS--RTKIYIILEYITGGEL------- 94
Query: 190 FDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYHSL 249
FD I + G+L E A K + +G+ Y +G+ HRDLKP+N+LLD +L
Sbjct: 95 FDKIVR-----NGRLSESE--ARKYFHQLIDGVDYCHSKGVYHRDLKPENLLLDS-QGNL 146
Query: 250 RISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQPF 309
+ISDFG S + + L GTP + APE+ + + +
Sbjct: 147 KISDFGLSALPEQGVTI------------LKTTCGTPNYVAPEVLSHKGYNGAVA----- 189
Query: 310 KIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIYGWIHEYVVNRM 369
D+WS G+ +Y ++ LPF E D L + ++ + + + + ++NR+
Sbjct: 190 --DIWSCGVILYVLMAGYLPF---DEMDLPTL--YSKIDKAEFSCPSYFALGAKSLINRI 242
Query: 370 LSKNTASRPTTSNI 383
L N +R T + I
Sbjct: 243 LDPNPETRITIAEI 256
>At2g25880 [D] KOG0580 Serine/threonine protein kinase
Length = 282
Score = 80.9 bits (198), Expect = 4e-15
Identities = 87/331 (26%), Positives = 139/331 (41%), Gaps = 83/331 (25%)
Query: 64 EHAQK--FVNQYRIGERLGCGQFGTVY--KGHTTGKVVAIKQIYKKPMNSPFSMSLIMKT 119
E AQK + + IG+ LG G+FG VY + + +VA+K ++K +
Sbjct: 8 EAAQKRWTTSDFDIGKPLGRGKFGHVYLAREKRSDHIVALKVLFKAQLQQ---------- 57
Query: 120 MKRYESISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQ--IWLIQPLA 177
++R E + S L HPN+++L + DQ ++LI A
Sbjct: 58 --------------SQVEHQLRREVEIQSHLRHPNILRLY----GYFYDQKRVYLILEYA 99
Query: 178 VLGELQWSRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKP 237
V GEL + +++ K F E A + ++ L Y G+ +IHRD+KP
Sbjct: 100 VRGEL-------YKELQKCKYFS-------ERRAATYVASLARALIYCHGKHVIHRDIKP 145
Query: 238 QNILLDPVYHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFA 297
+N+L+ L+I+DFG S+ F + + GT + PE+
Sbjct: 146 ENLLIG-AQGELKIADFGWSV--------------HTFNRR-RTMCGTLDYLPPEMVESV 189
Query: 298 EGSAHASNEQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQL----KPDVHN 353
E A +D+WSLGI Y LY V PF +TY I L KP V +
Sbjct: 190 EHDA--------SVDIWSLGILCYEFLYGVPPFEAREHSETYKRIVQVDLKFPPKPIVSS 241
Query: 354 SSNIYGWIHEYVVNRMLSKNTASRPTTSNIL 384
S+ + ++++ML K + R +L
Sbjct: 242 SA-------KDLISQMLVKESTQRLALHKLL 265
>7302464 [R] KOG0586 Serine/threonine protein kinase
Length = 739
Score = 80.9 bits (198), Expect = 4e-15
Identities = 91/324 (28%), Positives = 149/324 (45%), Gaps = 73/324 (22%)
Query: 63 EEHAQKFVNQYRIGERLGCGQFGTVY--KGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTM 120
EEH + +Y++ + +G G F V K TGK VAIK I K +N P S+ + +
Sbjct: 145 EEH----IGKYKLIKTIGKGNFAKVKLAKHLPTGKEVAIKIIDKTQLN-PGSLQKLFR-- 197
Query: 121 KRYESISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLG 180
+V IM+M L+HPN+++L + +++ + ++LI A G
Sbjct: 198 --------EVRIMKM--------------LDHPNIVKLFQVIETEKT--LYLIMEYASGG 233
Query: 181 ELQWSRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNI 240
E+ FD + G++ +E VK I + +QY + IIHRDLK +N+
Sbjct: 234 EV-------FDYL-----VLHGRMKE-KEARVK-FRQIVSAVQYCHQKRIIHRDLKAENL 279
Query: 241 LLDPVYHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGS 300
LLD + ++I+DFG S F G D F G+P + APEL +G
Sbjct: 280 LLDSELN-IKIADFGFSN------EFTPGSKLDTF-------CGSPPYAAPELF---QGK 322
Query: 301 AHASNEQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIYGW 360
+ E +DVWSLG+ +Y ++ LPF G T + + + + + S++
Sbjct: 323 KYDGPE----VDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDC--- 375
Query: 361 IHEYVVNRMLSKNTASRPTTSNIL 384
E ++ + L N A R + I+
Sbjct: 376 --ENLLRKFLVLNPAKRASLETIM 397
>7299437 [R] KOG0586 Serine/threonine protein kinase
Length = 604
Score = 80.9 bits (198), Expect = 4e-15
Identities = 76/262 (29%), Positives = 119/262 (45%), Gaps = 64/262 (24%)
Query: 73 YRIGERLGCGQFGTVYKGH--TTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISGDV 130
Y+I + LG G F V TG+ VAIK I K +N+ I+
Sbjct: 63 YKIIKTLGKGNFAKVKLAIHLPTGREVAIKLIDKTALNT----------------IARQK 106
Query: 131 LIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESKF 190
L E+N+ K KLNHPN+++LL+ ++S + ++L+ GEL F
Sbjct: 107 LYREVNIMK---------KLNHPNIVRLLQVIESERT--LYLVMEYVSGGEL-------F 148
Query: 191 DLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYHSLR 250
+ + + G++ E A + + + ++Y + I+HRDLK +N+LLD L+
Sbjct: 149 NYLVK-----NGRMR--ERDARVLFRQLVSAIEYCHSKSIVHRDLKAENLLLDQ-QMKLK 200
Query: 251 ISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQPFK 310
I+DFG S K P L G+P + APEL G ++ E
Sbjct: 201 IADFGFSTTFEPKAP-------------LETFCGSPPYAAPEL---FRGKKYSGPE---- 240
Query: 311 IDVWSLGITVYAILYNVLPFWG 332
+D WSLG+ +Y ++ LPF G
Sbjct: 241 VDSWSLGVVLYTLVSGSLPFDG 262
>Hs4502557 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 473
Score = 80.5 bits (197), Expect = 5e-15
Identities = 70/242 (28%), Positives = 111/242 (44%), Gaps = 54/242 (22%)
Query: 94 GKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISGDVLIMEMNVSKIRWECFVTSKLNHP 153
G + + +K P+++ ++ KT+ + +R E V +L+HP
Sbjct: 55 GATSIVYRCKQKGTQKPYALKVLKKTVDK---------------KIVRTEIGVLLRLSHP 99
Query: 154 NVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESKFDLIEQWKSFYRGQLDSVEEFAVK 213
N+I+L E ++P +I L+ L GEL FD I + K +Y E A
Sbjct: 100 NIIKLKEIFETP--TEISLVLELVTGGEL-------FDRIVE-KGYYS------ERDAAD 143
Query: 214 VLGDISNGLQYLQGQGIIHRDLKPQNIL-LDPVYHS-LRISDFGCSLIVPSKLPFKDGRL 271
+ I + YL GI+HRDLKP+N+L P + L+I+DFG S IV ++ K
Sbjct: 144 AVKQILEAVAYLHENGIVHRDLKPENLLYATPAPDAPLKIADFGLSKIVEHQVLMK---- 199
Query: 272 QDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQPFKIDVWSLGITVYAILYNVLPFW 331
+ GTP + APE+ G A+ ++D+WS+GI Y +L PF+
Sbjct: 200 ---------TVCGTPGYCAPEI---LRGCAYGP-----EVDMWSVGIITYILLCGFEPFY 242
Query: 332 GE 333
E
Sbjct: 243 DE 244
>Hs21361133 [R] KOG0586 Serine/threonine protein kinase
Length = 752
Score = 80.5 bits (197), Expect = 5e-15
Identities = 89/337 (26%), Positives = 149/337 (43%), Gaps = 78/337 (23%)
Query: 67 QKFVNQYRIGERLGCGQFGTVYKGH--TTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYE 124
Q + YR+ + +G G F V TG+ VAIK I K +N P S+ + +
Sbjct: 50 QPHIGNYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLN-PTSLQKLFR------ 102
Query: 125 SISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQW 184
E+ + KI LNHPN+++L E +++ + ++LI A GE+
Sbjct: 103 ---------EVRIMKI---------LNHPNIVKLFEVIETEKT--LYLIMEYASGGEV-- 140
Query: 185 SRESKFDLI--------EQWKSFYRGQLDSVEEFAVKVLGD--------ISNGLQYLQGQ 228
FD + ++ +S +R + + V+V D I + +QY +
Sbjct: 141 -----FDYLVAHGKMKEKEARSKFRQGCQAGQTIKVQVSFDLLSLMFTFIVSAVQYCHQK 195
Query: 229 GIIHRDLKPQNILLDPVYHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLF 288
I+HRDLK +N+LLD + ++I+DFG S F G D F G+P +
Sbjct: 196 RIVHRDLKAENLLLDADMN-IKIADFGFSN------EFTVGGKLDTF-------CGSPPY 241
Query: 289 TAPELCNFAEGSAHASNEQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLK 348
APEL +G + E +DVWSLG+ +Y ++ LPF G+ + + + +
Sbjct: 242 AAPELF---QGKKYDGPE----VDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYR 294
Query: 349 PDVHNSSNIYGWIHEYVVNRMLSKNTASRPTTSNILR 385
+ S++ E ++ R L N R T I++
Sbjct: 295 IPFYMSTDC-----ENLLKRFLVLNPIKRGTLEQIMK 326
>At5g19360 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 523
Score = 80.5 bits (197), Expect = 5e-15
Identities = 87/322 (27%), Positives = 132/322 (40%), Gaps = 74/322 (22%)
Query: 71 NQYRIGERLGCGQFGTVY--KGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISG 128
+ Y +G+ LG GQFG + TG A K I K+
Sbjct: 66 SSYTLGKELGRGQFGVTHLCTQKATGLQFACKTIAKRK---------------------- 103
Query: 129 DVLIMEMNVSKIRWECFVTSKLN-HPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRE 187
L+ + ++ +R E + L PN+++L + +S + L+ L GEL
Sbjct: 104 --LVNKEDIEDVRREVQIMHHLTGQPNIVELKGAYEDKHS--VHLVMELCAGGEL----- 154
Query: 188 SKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILL--DPV 245
FD I K Y E A +L I + G+IHRDLKP+N LL
Sbjct: 155 --FDRIIA-KGHYS------ERAAASLLRTIVQIIHTCHSMGVIHRDLKPENFLLLSKDE 205
Query: 246 YHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASN 305
L+ +DFG S+ FKD IVG+ + APE+ G
Sbjct: 206 NSPLKATDFGLSVFYKPGEVFKD-------------IVGSAYYIAPEVLRRKYGP----- 247
Query: 306 EQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIYGWIH--- 362
+ D+WS+G+ +Y +L V PFW E+E +N I L V SS+ + I
Sbjct: 248 ----EADIWSIGVMLYILLCGVPPFWAESENGIFNAI----LSGQVDFSSDPWPVISPQA 299
Query: 363 EYVVNRMLSKNTASRPTTSNIL 384
+ +V +ML+ + R T + +L
Sbjct: 300 KDLVRKMLNSDPKQRLTAAQVL 321
>At5g12180 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 528
Score = 80.5 bits (197), Expect = 5e-15
Identities = 87/320 (27%), Positives = 132/320 (41%), Gaps = 74/320 (23%)
Query: 73 YRIGERLGCGQFGTVY--KGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISGDV 130
Y +G+ LG GQFG + TG A K I K+
Sbjct: 73 YSLGKELGRGQFGVTHLCTQKATGHQFACKTIAKRK------------------------ 108
Query: 131 LIMEMNVSKIRWECFVTSKLN-HPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESK 189
L+ + ++ +R E + L PN+++L + +S + L+ L GEL
Sbjct: 109 LVNKEDIEDVRREVQIMHHLTGQPNIVELKGAYEDKHS--VHLVMELCAGGEL------- 159
Query: 190 FDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILL--DPVYH 247
FD I K Y E A +L I + G+IHRDLKP+N LL
Sbjct: 160 FDRIIA-KGHYS------ERAAASLLRTIVQIVHTCHSMGVIHRDLKPENFLLLNKDENS 212
Query: 248 SLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQ 307
L+ +DFG S+ FKD IVG+ + APE+ G
Sbjct: 213 PLKATDFGLSVFYKPGEVFKD-------------IVGSAYYIAPEVLKRKYGP------- 252
Query: 308 PFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIYGWIH---EY 364
+ D+WS+G+ +Y +L V PFW E+E +N I L+ V SS+ + I +
Sbjct: 253 --EADIWSIGVMLYILLCGVPPFWAESENGIFNAI----LRGHVDFSSDPWPSISPQAKD 306
Query: 365 VVNRMLSKNTASRPTTSNIL 384
+V +ML+ + R T + +L
Sbjct: 307 LVKKMLNSDPKQRLTAAQVL 326
>At4g36070 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 536
Score = 80.5 bits (197), Expect = 5e-15
Identities = 74/296 (25%), Positives = 119/296 (40%), Gaps = 80/296 (27%)
Query: 65 HAQKFVNQYRIGERLGCGQFGTVYKG--HTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKR 122
+A+ F N+Y IG+ LG GQFG Y + G VA+K+I K M P + + + +K
Sbjct: 63 YAKDFDNRYTIGKLLGHGQFGFTYVATDNNNGNRVAVKRIDKAKMTQPIEVEDVKREVKI 122
Query: 123 YESISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGEL 182
+++ G H NV+ + I+++ L GEL
Sbjct: 123 LQALGG-----------------------HENVVGFHNAFED--KTYIYIVMELCDGGEL 157
Query: 183 QWSRESKFDLIEQWKSFYRGQLDSV------EEFAVKVLGDISNGLQYLQGQGIIHRDLK 236
LD + E+ A V+ + +G++HRD+K
Sbjct: 158 ---------------------LDRILANRYTEKDAAVVVRQMLKVAAECHLRGLVHRDMK 196
Query: 237 PQNILLDPVYH--SLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELC 294
P+N L SL+ +DFG S + + F+D IVG+ + APE+
Sbjct: 197 PENFLFKSTEEGSSLKATDFGLSDFIKPGVKFQD-------------IVGSAYYVAPEVL 243
Query: 295 NFAEGSAHASNEQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPD 350
G + DVWS+G+ Y +L PFW +T+ +N + + KPD
Sbjct: 244 KRRSGP---------ESDVWSIGVITYILLCGRRPFWDKTQDGIFNEVMRK--KPD 288
>At4g30960 [T] KOG0583 Serine/threonine protein kinase
Length = 441
Score = 80.5 bits (197), Expect = 5e-15
Identities = 85/318 (26%), Positives = 133/318 (41%), Gaps = 72/318 (22%)
Query: 72 QYRIGERLGCGQFGTVYKGHT--TGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISGD 129
+Y +G LG G F VY TGK VA+K + K+ +
Sbjct: 23 RYELGRLLGHGTFAKVYHARNIQTGKSVAMKVVGKEKV---------------------- 60
Query: 130 VLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESK 189
+ V +I+ E V + HPN+++L E + S +I+ L GEL +++ +K
Sbjct: 61 --VKVGMVDQIKREISVMRMVKHPNIVELHEVMAS--KSKIYFAMELVRGGEL-FAKVAK 115
Query: 190 FDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYHSL 249
L E Y QL S +F +G+ HRDLKP+N+LLD +L
Sbjct: 116 GRLREDVARVYFQQLISAVDFC--------------HSRGVYHRDLKPENLLLDE-EGNL 160
Query: 250 RISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQPF 309
+++DFG S F + QD L+ GTP + APE+ +G A
Sbjct: 161 KVTDFGLS-------AFTEHLKQDGL---LHTTCGTPAYVAPEVI-LKKGYDGA------ 203
Query: 310 KIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIYGWIH---EYVV 366
K D+WS G+ ++ +L LPF + + Y I K GW+ +V
Sbjct: 204 KADLWSCGVILFVLLAGYLPFQDDNLVNMYRKIYRGDFK--------CPGWLSSDARRLV 255
Query: 367 NRMLSKNTASRPTTSNIL 384
++L N +R T ++
Sbjct: 256 TKLLDPNPNTRITIEKVM 273
>At4g09570 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 501
Score = 80.5 bits (197), Expect = 5e-15
Identities = 77/278 (27%), Positives = 121/278 (42%), Gaps = 69/278 (24%)
Query: 71 NQYRIGERLGCGQFGTVY--KGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISG 128
+ Y +G++LG GQFGT Y ++ A K I K+ + + YE +
Sbjct: 23 DHYLLGKKLGQGQFGTTYLCTEKSSSANYACKSIPKRKL----------VCREDYEDVWR 72
Query: 129 DVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIW--LIQPLAVLGELQWSR 186
++ IM ++S+ HPNV+++ Y D ++ ++ + GEL
Sbjct: 73 EIQIMH-HLSE------------HPNVVRI----KGTYEDSVFVHIVMEVCEGGEL---- 111
Query: 187 ESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVY 246
FD I F E A K++ I ++ G++HRDLKP+N L D
Sbjct: 112 ---FDRIVSKGCFS-------EREAAKLIKTILGVVEACHSLGVMHRDLKPENFLFDSPS 161
Query: 247 HS--LRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHAS 304
L+ +DFG S+ +K G+ L +VG+P + APE+ G
Sbjct: 162 DDAKLKATDFGLSVF------YKPGQY-------LYDVVGSPYYVAPEVLKKCYGP---- 204
Query: 305 NEQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLI 342
+IDVWS G+ +Y +L V PFW ETE + I
Sbjct: 205 -----EIDVWSAGVILYILLSGVPPFWAETESGIFRQI 237
>At2g17890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 571
Score = 80.5 bits (197), Expect = 5e-15
Identities = 82/330 (24%), Positives = 137/330 (40%), Gaps = 76/330 (23%)
Query: 65 HAQKFVNQYRIGERLGCGQFGTVYKG--HTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKR 122
+A+ F ++Y IG+ LG GQFG Y TG VA+K+I K M P ++ + + +K
Sbjct: 100 YAKDFDHRYTIGKLLGHGQFGYTYVATDKKTGDRVAVKKIDKAKMTIPIAVEDVKREVKI 159
Query: 123 YESISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGEL 182
++++G H NV++ + S ++++ L GEL
Sbjct: 160 LQALTG-----------------------HENVVRFYNAFEDKNS--VYIVMELCEGGEL 194
Query: 183 QWSRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILL 242
D I K + D A V+ + +G++HRD+KP+N L
Sbjct: 195 -------LDRILARKDSRYSERD-----AAVVVRQMLKVAAECHLRGLVHRDMKPENFLF 242
Query: 243 DPVYHS--LRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGS 300
L+ +DFG S + K G K+ + IVG+ + APE+ G
Sbjct: 243 KSTEEDSPLKATDFGLSDFI------KPG-------KKFHDIVGSAYYVAPEVLKRRSGP 289
Query: 301 AHASNEQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLIC------HRQLKPDVHNS 354
+ DVWS+G+ Y +L PFW +TE + + R+ P + NS
Sbjct: 290 ---------ESDVWSIGVISYILLCGRRPFWDKTEDGIFKEVLKNKPDFRRKPWPTISNS 340
Query: 355 SNIYGWIHEYVVNRMLSKNTASRPTTSNIL 384
+ + V ++L K+ +R T + L
Sbjct: 341 AKDF-------VKKLLVKDPRARLTAAQAL 363
>At1g18890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 545
Score = 80.5 bits (197), Expect = 5e-15
Identities = 75/270 (27%), Positives = 113/270 (41%), Gaps = 67/270 (24%)
Query: 71 NQYRIGERLGCGQFGTVY--KGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISG 128
++Y +G LG G+FG Y T + +A K I K+ + +
Sbjct: 61 DKYILGRELGRGEFGITYLCTDRETHEALACKSISKRKLRTA------------------ 102
Query: 129 DVLIMEMNVSKIRWECFVTSKL-NHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRE 187
+++ +R E + S L HPNV++L + ++ + L+ L GEL
Sbjct: 103 ------VDIEDVRREVAIMSTLPEHPNVVKLKASYED--NENVHLVMELCEGGEL----- 149
Query: 188 SKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYH 247
FD I RG E A V I+ + G++HRDLKP+N L
Sbjct: 150 --FDRIVA-----RGHY--TERAAAAVARTIAEVVMMCHSNGVMHRDLKPENFLFANKKE 200
Query: 248 S--LRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASN 305
+ L+ DFG S+ FK G + +IVG+P + APE+ G
Sbjct: 201 NSPLKAIDFGLSVF------FKPG-------DKFTEIVGSPYYMAPEVLKRDYGPG---- 243
Query: 306 EQPFKIDVWSLGITVYAILYNVLPFWGETE 335
+DVWS G+ +Y +L V PFW ETE
Sbjct: 244 -----VDVWSAGVIIYILLCGVPPFWAETE 268
>YFR014c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 446
Score = 80.1 bits (196), Expect = 6e-15
Identities = 85/325 (26%), Positives = 140/325 (42%), Gaps = 78/325 (24%)
Query: 72 QYRIGERLGCGQFGTVY--KGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISGD 129
+Y G+ LG G FG V K TG+ VA+K + KK + + +
Sbjct: 36 KYVFGKTLGAGTFGVVRQAKNTETGEDVAVKILIKKALKG--------------NKVQLE 81
Query: 130 VLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESK 189
L E+++ + +L+HPN++ + +S D+ ++I LA GEL
Sbjct: 82 ALYDELDILQ---------RLHHPNIVAFKDWFES--KDKFYIITQLAKGGEL------- 123
Query: 190 FDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNIL-LDPVYHS 248
FD I + F EE AV++L +I + ++Y+ Q I+HRDLKP+N+L +D S
Sbjct: 124 FDRILKKGKF-------TEEDAVRILVEILSAVKYMHSQNIVHRDLKPENLLYIDKSDES 176
Query: 249 -LRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQ 307
L ++DFG + + S E+ L K G+ + APE+ H
Sbjct: 177 PLVVADFGIAKRLKSD------------EELLYKPAGSLGYVAPEVLT---QDGHGK--- 218
Query: 308 PFKIDVWSLGITVYAIL--------YNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIYG 359
D+WS+G+ Y +L V F E Y + HR V N + +
Sbjct: 219 --PCDIWSIGVITYTLLCGYSAFRAERVQDFLDECTTGEYPVKFHRPYWDSVSNKAKQF- 275
Query: 360 WIHEYVVNRMLSKNTASRPTTSNIL 384
+ + L+ + + RPT + +L
Sbjct: 276 ------ILKALNLDPSKRPTAAELL 294
>SPAC1F5.09c [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 589
Score = 80.1 bits (196), Expect = 6e-15
Identities = 93/385 (24%), Positives = 153/385 (39%), Gaps = 65/385 (16%)
Query: 3 KYPTIIQFPESIRIQPMSTDPESYFQIIDEQQKKLELGVISKTKIIERYVXXXXXXXXXQ 62
K T IQ + I+P D I+ + K+ + SK + R
Sbjct: 239 KPKTTIQTDKKHIIRPFIEDKSHVESIMTGKVTKVPVKADSKNTLSRRMTDRQALAMLKD 298
Query: 63 EEHAQKFVNQYRIGERLGCGQFGTVYKGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKR 122
+ V + + +LG G G+VY KVV KQ+ +S S+ ++ R
Sbjct: 299 SVTSHDPVEYFNVKHKLGQGASGSVY----LAKVVGGKQL--GIFDSVAIKSIDLQCQTR 352
Query: 123 YESISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGEL 182
E I ++ +M ++ HPN++ L+ +W++ G L
Sbjct: 353 KELILNEITVMRESI--------------HPNIVTYLDSF-LVRERHLWVVMEYMNAGSL 397
Query: 183 QWSRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILL 242
D+IE+ K E ++ + G+Q+L + IIHRD+K N+LL
Sbjct: 398 T-------DIIEKSKL--------TEAQIARICLETCKGIQHLHARNIIHRDIKSDNVLL 442
Query: 243 DPVYHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAH 302
D +++I+DFG RL + K + +VGTP + APE+
Sbjct: 443 DN-SGNIKITDFGFC-----------ARLSNRTNKRVT-MVGTPYWMAPEVVK------- 482
Query: 303 ASNEQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHR---QLKPDVHNSSNIYG 359
NE K+D+WSLGI + ++ N P+ E LI LK S N+
Sbjct: 483 -QNEYGTKVDIWSLGIMIIEMIENEPPYLREDPIRALYLIAKNGTPTLKKPNLVSKNLKS 541
Query: 360 WIHEYVVNRMLSKNTASRPTTSNIL 384
++ N L+ +T R T + +L
Sbjct: 542 FL-----NSCLTIDTIFRATAAELL 561
>At4g32830 [D] KOG0580 Serine/threonine protein kinase
Length = 294
Score = 80.1 bits (196), Expect = 6e-15
Identities = 78/283 (27%), Positives = 120/283 (41%), Gaps = 70/283 (24%)
Query: 70 VNQYRIGERLGCGQFGTVY--KGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESIS 127
++ + IG+ LG G+FG VY + + VVA+K ++K S S + ++R
Sbjct: 28 LSDFDIGKPLGRGKFGHVYLAREKRSNHVVALKVLFK----SQLQQSQVEHQLRR----- 78
Query: 128 GDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQ--IWLIQPLAVLGELQWS 185
E + S L HPN+++L + DQ ++LI A GEL
Sbjct: 79 ---------------EVEIQSHLRHPNILRLY----GYFYDQKRVYLILEYAARGEL--- 116
Query: 186 RESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPV 245
+ +++ K F E A + ++ L Y G+ +IHRD+KP+N+L+
Sbjct: 117 ----YKDLQKCKYFS-------ERRAATYVASLARALIYCHGKHVIHRDIKPENLLIG-A 164
Query: 246 YHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASN 305
L+I+DFG S+ F + + GT + PE+ E A
Sbjct: 165 QGELKIADFGWSV--------------HTFNRR-RTMCGTLDYLPPEMVESVEHDA---- 205
Query: 306 EQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLK 348
+D+WSLGI Y LY V PF DTY I LK
Sbjct: 206 ----SVDIWSLGILCYEFLYGVPPFEAMEHSDTYRRIVQVDLK 244
>At3g19100 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 599
Score = 80.1 bits (196), Expect = 6e-15
Identities = 82/326 (25%), Positives = 133/326 (40%), Gaps = 68/326 (20%)
Query: 66 AQKFVNQYRIGERLGCGQFGTVY-----KGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTM 120
+++ ++ +GE +G G FG KG + VA+K I K M S S+ + + +
Sbjct: 137 SKELQSRIELGEEIGRGHFGYTCSAKFKKGELKDQEVAVKVIPKSKMTSAISIEDVRREV 196
Query: 121 KRYESISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLG 180
K ++SG H N++Q + + + ++++ L G
Sbjct: 197 KILRALSG-----------------------HQNLVQFYDAFED--NANVYIVMELCGGG 231
Query: 181 ELQWSRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNI 240
EL D I RG S E+ A VL I N + + QG++HRDLKP+N
Sbjct: 232 EL-------LDRI-----LARGGKYS-EDDAKAVLIQILNVVAFCHLQGVVHRDLKPENF 278
Query: 241 LLDPVYHS--LRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAE 298
L + L++ DFG S V ++ LN IVG+ + APE+ +
Sbjct: 279 LYTSKEENSMLKVIDFGLSDFVRP-------------DERLNDIVGSAYYVAPEVLH--- 322
Query: 299 GSAHASNEQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIY 358
+ DVWS+G+ Y +L PFW TE + + D ++
Sbjct: 323 ------RSYTTEADVWSIGVIAYILLCGSRPFWARTESGIFRAVLKADPSFDEPPWPSLS 376
Query: 359 GWIHEYVVNRMLSKNTASRPTTSNIL 384
++ V R+L K+ R T S L
Sbjct: 377 FEAKDF-VKRLLYKDPRKRMTASQAL 401
>At1g48260 [T] KOG0583 Serine/threonine protein kinase
Length = 432
Score = 80.1 bits (196), Expect = 6e-15
Identities = 82/259 (31%), Positives = 124/259 (47%), Gaps = 52/259 (20%)
Query: 132 IMEMNVS-KIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESKF 190
I +NVS +I+ E L HPN+++L E L S +I+++ G+L F
Sbjct: 47 ITRLNVSFQIKREIRTLKVLKHPNIVRLHEVLAS--KTKIYMVLECVTGGDL-------F 97
Query: 191 DLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYHSLR 250
D I +G+L + K+ + +G+ Y +G+ HRDLK +N+LLD H ++
Sbjct: 98 DRIVS-----KGKLSETQ--GRKMFQQLIDGVSYCHNKGVFHRDLKLENVLLDAKGH-IK 149
Query: 251 ISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPE-LCNFAEGSAHASNEQPF 309
I+DFG S + S+ +DG L+ G+P + APE L N EG A++
Sbjct: 150 ITDFGLSAL--SQHYREDGL--------LHTTCGSPNYVAPEVLAN--EGYDGAAS---- 193
Query: 310 KIDVWSLGITVYAILYNVLPFWGETEFDTYNL--ICHRQLKPDVHNSSNIYGWIH---EY 364
D+WS G+ +Y IL LP FD NL IC + K D I WI +
Sbjct: 194 --DIWSCGVILYVILTGCLP------FDDANLAVICRKIFKGD----PPIPRWISLGAKT 241
Query: 365 VVNRMLSKNTASRPTTSNI 383
++ RML N +R T + I
Sbjct: 242 MIKRMLDPNPVTRVTIAGI 260
>7294537 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 835
Score = 80.1 bits (196), Expect = 6e-15
Identities = 82/272 (30%), Positives = 122/272 (44%), Gaps = 67/272 (24%)
Query: 72 QYRIGERLGCGQFGTVYKGHTTGK--VVAIKQIYKKPMNSPFSMSLIMKTMKRYESISGD 129
+Y + LG G F VYKG K VAIK I KK + +L+ K +K + ++
Sbjct: 8 EYSSKDMLGHGAFAVVYKGRHRKKHMPVAIKCITKKGQLK--TQNLLGKEIKILKELT-- 63
Query: 130 VLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESK 189
+L+H NV+ LL+C +S D + L+ G+L K
Sbjct: 64 -------------------ELHHENVVALLDCKES--QDCVSLVMEYCNGGDLADYLSVK 102
Query: 190 FDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYHSL 249
L E D+V F V++ G ++ L +GI+HRDLKPQNILL
Sbjct: 103 GTLSE----------DTVRLFLVQLAG----AMKALYTKGIVHRDLKPQNILLS------ 142
Query: 250 RISDFGCSLIVPSKLPFKDGRLQDL-FEKELNK------IVGTPLFTAPELCNFAEGSAH 302
++G +L PSK+ K + D F + LN+ + G+P++ APE+
Sbjct: 143 --HNYGKTLPAPSKITLK---IADFGFARFLNEGAMAATLCGSPMYMAPEVI-------- 189
Query: 303 ASNEQPFKIDVWSLGITVYAILYNVLPFWGET 334
S + K D+WSLG VY L PF+ +T
Sbjct: 190 MSLQYDSKADLWSLGTIVYQCLTGKAPFYAQT 221
>CE18967 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD and related
proteins
Length = 1101
Score = 79.7 bits (195), Expect = 8e-15
Identities = 75/273 (27%), Positives = 120/273 (43%), Gaps = 65/273 (23%)
Query: 62 QEEHAQKFVNQYRIGERLGCGQFGTVYKG--HTTGKVVAIKQIYKKPMNSPFSMSLIMKT 119
Q EH + Q E LG GQFGTVY G G+ VA+K I K +K
Sbjct: 759 QTEHEFSQLYQIFAEEVLGSGQFGTVYGGIHRRNGQHVAVKLIDK------------LKF 806
Query: 120 MKRYESISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVL 179
E + +R E + K++HP V+ ++ L++ +D+I+++
Sbjct: 807 PPNKEDL-------------LRAEVQILEKVDHPGVVHFMQMLET--TDRIFVVM----- 846
Query: 180 GELQWSRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQN 239
+ K D++E S +G+L E ++ I L+YL I+H DLKP+N
Sbjct: 847 ------EKLKGDMLEMILSSEKGRLS--ERTTQFLVAQILEALRYLHHLNIVHCDLKPEN 898
Query: 240 ILL--DPVYHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFA 297
ILL + + +++ DFG + I+ K F+ +VGTP + APE+
Sbjct: 899 ILLNSNSDFPQVKLCDFGFARIIGEK-SFR------------RSVVGTPAYLAPEVLR-- 943
Query: 298 EGSAHASNEQPFKIDVWSLGITVYAILYNVLPF 330
+ +D+WS+G+ VY L PF
Sbjct: 944 ------NKGFNRSLDMWSVGVIVYVSLSGTFPF 970
>At5g23580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 490
Score = 79.7 bits (195), Expect = 8e-15
Identities = 82/320 (25%), Positives = 139/320 (42%), Gaps = 70/320 (21%)
Query: 71 NQYRIGERLGCGQFGTVY--KGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISG 128
+ Y +G+ LG GQFGT + TG+ +A K I K+ + + Y+ +
Sbjct: 20 DNYFLGQVLGQGQFGTTFLCTHKQTGQKLACKSIPKRKL----------LCQEDYDDVLR 69
Query: 129 DVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSD--QIWLIQPLAVLGELQWSR 186
++ IM ++S+ +PNV+++ +S Y D + L+ L GEL
Sbjct: 70 EIQIMH-HLSE------------YPNVVRI----ESAYEDTKNVHLVMELCEGGEL---- 108
Query: 187 ESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVY 246
FD I + RG E A K++ I ++ G++HRDLKP+N L
Sbjct: 109 ---FDRIVK-----RGHYSERE--AAKLIKTIVGVVEACHSLGVVHRDLKPENFLFSSSD 158
Query: 247 H--SLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHAS 304
SL+ +DFG S+ F + +VG+ + APE+ + G
Sbjct: 159 EDASLKSTDFGLSVFCTPGEAFSE-------------LVGSAYYVAPEVLHKHYGP---- 201
Query: 305 NEQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIYGWIHEY 364
+ DVWS G+ +Y +L PFW E+E + I +L+ +++ +I +
Sbjct: 202 -----ECDVWSAGVILYILLCGFPPFWAESEIGIFRKILQGKLEFEINPWPSISESAKD- 255
Query: 365 VVNRMLSKNTASRPTTSNIL 384
++ +ML N R T +L
Sbjct: 256 LIKKMLESNPKKRLTAHQVL 275
>At4g38230 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 484
Score = 79.7 bits (195), Expect = 8e-15
Identities = 86/322 (26%), Positives = 138/322 (42%), Gaps = 76/322 (23%)
Query: 73 YRIGERLGCGQFGTVY--KGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISGDV 130
Y +G +LG GQFGT Y K +TG+ A K I K+
Sbjct: 24 YSLGHKLGQGQFGTTYMCKEISTGREYACKSITKRK------------------------ 59
Query: 131 LIMEMNVSKIRWECFVTSKL-NHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESK 189
LI + +V +R E + L + N++ + + P + ++ L GEL
Sbjct: 60 LISKEDVEDVRREIQIMHHLAGYKNIVTIKGAYEDPL--YVHIVMELCSGGEL------- 110
Query: 190 FDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILL---DPVY 246
FD I Q RG E A +++ I ++ G++HRDLKP+N LL D +
Sbjct: 111 FDRIIQ-----RGHYS--ERKAAELIKIIVGVVEACHSLGVMHRDLKPENFLLVNKDDDF 163
Query: 247 HSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNE 306
SL+ DFG S+ FK G++ +VG+P + APE+ G
Sbjct: 164 -SLKAIDFGLSVF------FKPGQI-------FEDVVGSPYYVAPEVLLKHYGP------ 203
Query: 307 QPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIYGWIHE--- 363
+ DVW+ G+ +Y ++ V PFW ET+ ++ + LK + S+ + I +
Sbjct: 204 ---EADVWTAGVILYILVSGVPPFWAETQQGIFDAV----LKGHIDFDSDPWPLISDSAK 256
Query: 364 YVVNRMLSKNTASRPTTSNILR 385
++ ML + R T +LR
Sbjct: 257 NLIRGMLCSRPSERLTAHQVLR 278
>At3g56760 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 577
Score = 79.7 bits (195), Expect = 8e-15
Identities = 71/284 (25%), Positives = 118/284 (41%), Gaps = 67/284 (23%)
Query: 66 AQKFVNQYRIGERLGCGQFGTVY-----KGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTM 120
+++F + Y I +G G FG KG G+ VA+K I K M + ++ + + +
Sbjct: 117 SKQFASHYEIDGEVGRGHFGYTCSAKGKKGSLKGQDVAVKVIPKSKMTTAIAIEDVRREV 176
Query: 121 KRYESISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLG 180
K +++G H N++Q + + + ++++ L G
Sbjct: 177 KILRALTG-----------------------HKNLVQFYDAFED--DENVYIVMELCQGG 211
Query: 181 ELQWSRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNI 240
EL D I Q Y E A KV+ I + + Y QG++HRDLKP+N
Sbjct: 212 EL-------LDKILQRGGKYS------EVDAKKVMIQILSVVAYCHLQGVVHRDLKPENF 258
Query: 241 LLDPVYHS--LRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAE 298
L S L+ DFG S V ++ LN IVG+ + APE+ +
Sbjct: 259 LFTTKDESSPLKAIDFGLSDYVRP-------------DERLNDIVGSAYYVAPEVLHRTY 305
Query: 299 GSAHASNEQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLI 342
G+ + D+WS+G+ Y +L PFW +E + +
Sbjct: 306 GT---------EADMWSIGVIAYILLCGSRPFWARSESGIFRAV 340
>At3g17510 [T] KOG0583 Serine/threonine protein kinase
Length = 446
Score = 79.7 bits (195), Expect = 8e-15
Identities = 92/333 (27%), Positives = 136/333 (40%), Gaps = 81/333 (24%)
Query: 62 QEEHAQKFVN--QYRIGERLGCGQFGTVY--KGHTTGKVVAIKQIYKKPMNSPFSMSLIM 117
+E+ A+K + +Y +G LG G FG V K +G A+K I K
Sbjct: 7 EEKKAEKGMRLGKYELGRTLGEGNFGKVKFAKDTVSGHSFAVKIIDKSR----------- 55
Query: 118 KTMKRYESISGDVLIMEMNVS-KIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPL 176
I ++N S +I+ E L HP++++L E L S +I ++ L
Sbjct: 56 --------------IADLNFSLQIKREIRTLKMLKHPHIVRLHEVLAS--KTKINMVMEL 99
Query: 177 AVLGELQWSRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLK 236
GEL FD I G+L + K+ + +G+ Y +G+ HRDLK
Sbjct: 100 VTGGEL-------FDRIVS-----NGKLTETD--GRKMFQQLIDGISYCHSKGVFHRDLK 145
Query: 237 PQNILLDPVYHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNF 296
+N+LLD H ++I+DFG S + F+D L L+ G+P + APE+
Sbjct: 146 LENVLLDAKGH-IKITDFGLSALPQH---FRDDGL-------LHTTCGSPNYVAPEVLAN 194
Query: 297 AEGSAHASNEQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICH------RQLKPD 350
AS D+WS G+ +Y IL LPF Y IC R L P
Sbjct: 195 RGYDGAAS-------DIWSCGVILYVILTGCLPFDDRNLAVLYQKICKGDPPIPRWLSPG 247
Query: 351 VHNSSNIYGWIHEYVVNRMLSKNTASRPTTSNI 383
++ RML N +R T I
Sbjct: 248 ART-----------MIKRMLDPNPVTRITVVGI 269
>At1g49580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 606
Score = 79.7 bits (195), Expect = 8e-15
Identities = 73/284 (25%), Positives = 119/284 (41%), Gaps = 67/284 (23%)
Query: 66 AQKFVNQYRIGERLGCGQFGTVY-----KGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTM 120
+++F ++ +GE +G G FG KG G+VVA+K I K M + ++ + + +
Sbjct: 143 SKEFHSRVELGEEIGRGHFGYTCSAKFKKGELKGQVVAVKIIPKSKMTTAIAIEDVRREV 202
Query: 121 KRYESISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLG 180
K +++SG H N++Q + + + +++ L G
Sbjct: 203 KILQALSG-----------------------HKNLVQFYDAFED--NANVYIAMELCEGG 237
Query: 181 ELQWSRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNI 240
EL D I RG S E A V+ I N + + QG++HRDLKP+N
Sbjct: 238 EL-------LDRI-----LARGGKYS-ENDAKPVIIQILNVVAFCHFQGVVHRDLKPENF 284
Query: 241 LLDPVYHS--LRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAE 298
L + L+ DFG S V ++ LN IVG+ + APE+ +
Sbjct: 285 LYTSKEENSQLKAIDFGLSDFVRP-------------DERLNDIVGSAYYVAPEVLH--- 328
Query: 299 GSAHASNEQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLI 342
+ DVWS+G+ Y +L PFW TE + +
Sbjct: 329 ------RSYTTEADVWSIGVIAYILLCGSRPFWARTESGIFRAV 366
>Hs4758128_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 385
Score = 79.7 bits (195), Expect = 8e-15
Identities = 67/264 (25%), Positives = 118/264 (44%), Gaps = 66/264 (25%)
Query: 72 QYRIGERLGCGQFGTVYKGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISGDVL 131
+Y++G +G G F V K+ ++ +++ +I K+ R G
Sbjct: 45 RYKVGRTIGDGNFAVV------------KECVERSTAREYALKIIKKSKCR-----GKEH 87
Query: 132 IMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESKFD 191
+++ VS +R ++ HPN++ L+E +D P +++L+ L G+L FD
Sbjct: 88 MIQNEVSILR-------RVKHPNIVLLIEEMDVP--TELYLVMELVKGGDL-------FD 131
Query: 192 LIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILL---DPVYHS 248
I + E A +L ++++ ++YL I+HRD+KP+N+L+ S
Sbjct: 132 AITSTNKY-------TERDASGMLYNLASAIKYLHSLNIVHRDIKPENLLVYEHQDGSKS 184
Query: 249 LRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQP 308
L++ DFG + IV DG L + GTP + APE+ A
Sbjct: 185 LKLGDFGLATIV-------DG--------PLYTVCGTPTYVAPEII--------AETGYG 221
Query: 309 FKIDVWSLGITVYAILYNVLPFWG 332
K+D+W+ G+ Y +L PF G
Sbjct: 222 LKVDIWAAGVITYILLCGFPPFRG 245
>YDR477w [T] KOG0583 Serine/threonine protein kinase
Length = 633
Score = 79.3 bits (194), Expect = 1e-14
Identities = 77/267 (28%), Positives = 122/267 (44%), Gaps = 64/267 (23%)
Query: 70 VNQYRIGERLGCGQFGTVYKGH--TTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESIS 127
+ Y+I + LG G FG V + TTG+ VA+K I KK
Sbjct: 52 IGNYQIVKTLGEGSFGKVKLAYHTTTGQKVALKIINKK---------------------- 89
Query: 128 GDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRE 187
VL +I E L HP++I+L + + S D+I ++ ++++
Sbjct: 90 --VLAKSDMQGRIEREISYLRLLRHPHIIKLYDVIKS--KDEIIMV--------IEYAGN 137
Query: 188 SKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYH 247
FD I Q R ++ E+ A + I + ++Y I+HRDLKP+N+LLD +
Sbjct: 138 ELFDYIVQ-----RDKMS--EQEARRFFQQIISAVEYCHRHKIVHRDLKPENLLLDE-HL 189
Query: 248 SLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQ 307
+++I+DFG S I+ DG L G+P + APE+ + G +A E
Sbjct: 190 NVKIADFGLSNIM------TDGNF-------LKTSCGSPNYAAPEVIS---GKLYAGPE- 232
Query: 308 PFKIDVWSLGITVYAILYNVLPFWGET 334
+DVWS G+ +Y +L LPF E+
Sbjct: 233 ---VDVWSCGVILYVMLCRRLPFDDES 256
>Hs7657214 [T] KOG0583 Serine/threonine protein kinase
Length = 714
Score = 79.3 bits (194), Expect = 1e-14
Identities = 79/269 (29%), Positives = 122/269 (44%), Gaps = 67/269 (24%)
Query: 68 KFVNQYRIGER-LGCGQFGTVYKG-HT-TGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYE 124
K V Y IG R LG G F V +G H TG+ VAIK I KK + + K ++R
Sbjct: 56 KRVGNYLIGSRKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKD---TYVTKNLRR-- 110
Query: 125 SISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQW 184
E + + HPN+ QLL+ L++ S +L+ L G L
Sbjct: 111 ------------------EGQIQQMIRHPNITQLLDILETENS--YYLVMELCPGGNLMH 150
Query: 185 SRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDP 244
K + + +L+ E A + + + + +++L G++HRDLK +N+LLD
Sbjct: 151 ------------KIYEKKRLEESE--ARRYIRQLISAVEHLHRAGVVHRDLKIENLLLDE 196
Query: 245 VYHSLRISDFG---CSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSA 301
+++++ DFG C+ I+ PF G+P + APEL
Sbjct: 197 D-NNIKLIDFGLSNCAGILGYSDPFSTQ-------------CGSPAYAAPELL------- 235
Query: 302 HASNEQPFKIDVWSLGITVYAILYNVLPF 330
A + KIDVWS+G+ +YA+L LPF
Sbjct: 236 -ARKKYGPKIDVWSIGVNMYAMLTGTLPF 263
>Hs14916455 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 385
Score = 79.3 bits (194), Expect = 1e-14
Identities = 69/255 (27%), Positives = 117/255 (45%), Gaps = 56/255 (21%)
Query: 93 TGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISGDVLIMEMNVSKIRWECFVTSKLNH 152
TG + ++ +K PF++ K M+ E + + E++V + +++H
Sbjct: 71 TGSFSRVVRVEQKTTKKPFAI----KVMETREREGREACVSELSVLR---------RVSH 117
Query: 153 PNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESKFDLIEQWKSFYRGQLDSVEEFAV 212
++QL+E ++ DQ++++ LA GEL FD + SF E AV
Sbjct: 118 RYIVQLMEIFET--EDQVYMVMELATGGEL-------FDRLIAQGSF-------TERDAV 161
Query: 213 KVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYH-----SLRISDFGCSLIVPSKLPFK 267
++L +++G++YL I HR+LKP+N+L YH + I+DFG L +
Sbjct: 162 RILQMVADGIRYLHALQITHRNLKPENLL---YYHPGEESKILITDFG--------LAYS 210
Query: 268 DGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQPFKIDVWSLGITVYAILYNV 327
+ D K L GTP + APE+ +D+W+LG+ YA+L
Sbjct: 211 GKKSGDWTMKTL---CGTPEYIAPEVL--------LRKPYTSAVDMWALGVITYALLSGF 259
Query: 328 LPFWGETEFDTYNLI 342
LPF E++ Y I
Sbjct: 260 LPFDDESQTRLYRKI 274
>At5g57630 [T] KOG0583 Serine/threonine protein kinase
Length = 412
Score = 79.3 bits (194), Expect = 1e-14
Identities = 83/319 (26%), Positives = 136/319 (42%), Gaps = 69/319 (21%)
Query: 68 KFVNQYRIGERLGCGQFGTVYKGH--TTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYES 125
K + +Y IG +G G F V G+ T G VA+K I K
Sbjct: 7 KKIGKYEIGRTIGEGNFAKVKLGYDTTNGTYVAVKIIDKA-------------------- 46
Query: 126 ISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWS 185
++I + S+++ E LNHPN++Q+ E + + +I ++ G+L
Sbjct: 47 ----LVIQKGLESQVKREIRTMKLLNHPNIVQIHEVIGT--KTKICIVMEYVSGGQL--- 97
Query: 186 RESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPV 245
S G+ E A K+ + + + Y +G+ HRDLKPQN+LLD
Sbjct: 98 ------------SDRLGRQKMKESDARKLFQQLIDAVDYCHNRGVYHRDLKPQNLLLDS- 144
Query: 246 YHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASN 305
+L++SDFG S + K G + L+ G+P + APEL +G + A+
Sbjct: 145 KGNLKVSDFGLSAVP------KSGDM-------LSTACGSPCYIAPELI-MNKGYSGAA- 189
Query: 306 EQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIYGWIHEYV 365
+DVWS G+ ++ +L PF + T ++ + L+ D G +
Sbjct: 190 -----VDVWSCGVILFELLAGYPPF----DDHTLPVLYKKILRADYTFPPGFTGEQKRLI 240
Query: 366 VNRMLSKNTASRPTTSNIL 384
N +L N SR T + I+
Sbjct: 241 FN-ILDPNPLSRITLAEII 258
>At4g18700 [T] KOG0583 Serine/threonine protein kinase
Length = 489
Score = 79.3 bits (194), Expect = 1e-14
Identities = 74/275 (26%), Positives = 123/275 (43%), Gaps = 61/275 (22%)
Query: 70 VNQYRIGERLGCGQFGTVYKGHT--TGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESIS 127
+ +Y +G+ LG G F VY T + VAIK I K+ + +
Sbjct: 23 LGRYEMGKLLGHGTFAKVYLARNVKTNESVAIKVIDKEKV------------------LK 64
Query: 128 GDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRE 187
G + ++ I+ E + ++ HPN++QL E + + +I+ + GEL
Sbjct: 65 GGL------IAHIKREISILRRVRHPNIVQLFEVMAT--KAKIYFVMEYVRGGEL----- 111
Query: 188 SKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYH 247
+ +G+L EE A K + + + + +G+ HRDLKP+N+LLD
Sbjct: 112 --------FNKVAKGRLK--EEVARKYFQQLISAVTFCHARGVYHRDLKPENLLLDE-NG 160
Query: 248 SLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQ 307
+L++SDFG S + S +DG LF + GTP + APE+ A A+
Sbjct: 161 NLKVSDFGLSAV--SDQIRQDG----LF----HTFCGTPAYVAPEV--LARKGYDAA--- 205
Query: 308 PFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLI 342
K+D+WS G+ ++ ++ LPF Y I
Sbjct: 206 --KVDIWSCGVILFVLMAGYLPFHDRNVMAMYKKI 238
>YOL016c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 447
Score = 79.0 bits (193), Expect = 1e-14
Identities = 84/327 (25%), Positives = 146/327 (43%), Gaps = 70/327 (21%)
Query: 67 QKFVNQ--YRIGERLGCGQFGTVYKGH--TTGKVVAIKQIYKKPMNSPFSMSLIMKTMKR 122
+ +VN+ Y G LG G FG V + +T + VAIK + KK
Sbjct: 39 ESYVNRTNYIFGRTLGAGSFGVVRQARKLSTNEDVAIKILLKK----------------- 81
Query: 123 YESISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGEL 182
++ G+ + ++M + E + KL+HPN++ + +S D+ +++ LA GEL
Sbjct: 82 --ALQGNNVQLQM----LYEELSILQKLSHPNIVSFKDWFES--KDKFYIVTQLATGGEL 133
Query: 183 QWSRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNIL- 241
FD I RG+ V+ AV+++ I ++Y+ + ++HRDLKP+N+L
Sbjct: 134 -------FDRI-----LSRGKFTEVD--AVEIIVQILGAVEYMHSKNVVHRDLKPENVLY 179
Query: 242 LDPVYHS-LRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGS 300
+D +S L I+DFG + + + E + K G+ + APE+
Sbjct: 180 VDKSENSPLVIADFGIAKQLKGE------------EDLIYKAAGSLGYVAPEVLT---QD 224
Query: 301 AHASNEQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNS---SNI 357
H D+WS+G+ Y +L PF E+ + + C P + NI
Sbjct: 225 GHGK-----PCDIWSIGVITYTLLCGYSPFIAES-VEGFMEECTASRYPVTFHMPYWDNI 278
Query: 358 YGWIHEYVVNRMLSKNTASRPTTSNIL 384
+ +++ + L N A RPT + +L
Sbjct: 279 SIDVKRFIL-KALRLNPADRPTATELL 304
>HsM4505103 [R] KOG0586 Serine/threonine protein kinase
Length = 713
Score = 79.0 bits (193), Expect = 1e-14
Identities = 86/321 (26%), Positives = 142/321 (43%), Gaps = 69/321 (21%)
Query: 67 QKFVNQYRIGERLGCGQFGTVYKGH--TTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYE 124
Q + YR+ + +G G F V TG+ VAIK I K +N P S+ + +
Sbjct: 50 QPHIGNYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLN-PTSLQKLFR------ 102
Query: 125 SISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQW 184
E+ + KI LNHPN+++L E +++ + ++LI A G++
Sbjct: 103 ---------EVRIMKI---------LNHPNIVKLFEVIETQKT--LYLIMEYASGGKV-- 140
Query: 185 SRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDP 244
FD + G++ E A I + +QY + I+HRDLK +N+LLD
Sbjct: 141 -----FDYLVA-----HGRMKEKE--ARSKFRQIVSAVQYCHQKRIVHRDLKAENLLLDA 188
Query: 245 VYHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHAS 304
+ ++I+DFG S F G D F G+P + APEL +G +
Sbjct: 189 DMN-IKIADFGFSN------EFTVGGKLDTF-------CGSPPYAAPELF---QGKKYDG 231
Query: 305 NEQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIYGWIHEY 364
E +DVWSLG+ +Y ++ LPF G+ + + + + + S++ E
Sbjct: 232 PE----VDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDC-----EN 282
Query: 365 VVNRMLSKNTASRPTTSNILR 385
++ R L N R T I++
Sbjct: 283 LLKRFLVLNPIKRGTLEQIMK 303
>ECU01g0630 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 488
Score = 79.0 bits (193), Expect = 1e-14
Identities = 72/250 (28%), Positives = 124/250 (48%), Gaps = 46/250 (18%)
Query: 139 KIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESKFDLIEQWKS 198
K+ E + SKL++PNV+++ S S+ ++++ L G L L+++
Sbjct: 83 KLESEIAIHSKLDNPNVVKMYRSFRS--SEYVFMVLELCERGALD-------ALLKR--- 130
Query: 199 FYRGQLDSVEEFAVKVLGDISNGLQYLQGQ-GIIHRDLKPQNILLDPVYHSLRISDFGCS 257
G+L E + + GL YL ++HRDLK N+ LD ++ ++I DFG S
Sbjct: 131 --NGKLK--ERHVARFVKQTVEGLIYLHNSVSVVHRDLKLGNLFLDSKFN-VKIGDFGLS 185
Query: 258 LIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQPFKIDVWSLG 317
++ KDG EK++ + GTP + APE+ F + S H+ F+ D+WSLG
Sbjct: 186 AVI------KDG------EKKVT-MCGTPNYIAPEVL-FGKASGHS-----FEADIWSLG 226
Query: 318 ITVYAILYNVLPFWGETEFDTYNLI-CHRQLKPDVHNSSNIYGWIHEYV--VNRMLSKNT 374
+ +Y +L V PF + D Y +I + + P+ + S+ E + + ++L+ N
Sbjct: 227 VIIYTLLVGVPPFQKKNVEDIYKMIKLNNYIFPENCDLSS------EAIDLITQILNTNP 280
Query: 375 ASRPTTSNIL 384
RPT +IL
Sbjct: 281 LERPTLEHIL 290
>Hs4507271 [T] KOG0583 Serine/threonine protein kinase
Length = 433
Score = 78.6 bits (192), Expect = 2e-14
Identities = 74/281 (26%), Positives = 122/281 (43%), Gaps = 63/281 (22%)
Query: 68 KFVNQYRIGERLGCGQFGTVYKGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESIS 127
K + +Y +G+ LG G +G V + V+ + + ++ + I+K K +
Sbjct: 44 KLIGKYLMGDLLGEGSYGKVKE------VLDSETLCRRAVK-------ILKKKKLRRIPN 90
Query: 128 GDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRE 187
G E NV K E + +L H NVIQL++ L + +++++ V G +
Sbjct: 91 G-----EANVKK---EIQLLRRLRHKNVIQLVDVLYNEEKQKMYMVMEYCVCGMQE---- 138
Query: 188 SKFDLIEQWKSFYRGQLDSVEEFAVKVLG------DISNGLQYLQGQGIIHRDLKPQNIL 241
LDSV E V + +GL+YL QGI+H+D+KP N+L
Sbjct: 139 ---------------MLDSVPEKRFPVCQAHGYFCQLIDGLEYLHSQGIVHKDIKPGNLL 183
Query: 242 LDPVYHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSA 301
L +L+ISD G + + PF + G+P F PE+ N +
Sbjct: 184 L-TTGGTLKISDLG---VAEALHPF-------AADDTCRTSQGSPAFQPPEIANGLD--- 229
Query: 302 HASNEQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLI 342
FK+D+WS G+T+Y I + PF G+ + + I
Sbjct: 230 ---TFSGFKVDIWSAGVTLYNITTGLYPFEGDNIYKLFENI 267
>At1g29230 [T] KOG0583 Serine/threonine protein kinase
Length = 520
Score = 78.6 bits (192), Expect = 2e-14
Identities = 80/318 (25%), Positives = 138/318 (43%), Gaps = 66/318 (20%)
Query: 70 VNQYRIGERLGCGQFGTVYKGHT--TGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESIS 127
+ +Y +G+ LG G F VY +G VAIK I K+ K MK S
Sbjct: 71 MGKYELGKLLGHGTFAKVYLAQNIKSGDKVAIKVIDKE------------KIMK-----S 113
Query: 128 GDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRE 187
G V ++ +S +R ++ HP ++ L E + + +I+ + GEL
Sbjct: 114 GLVAHIKREISILR-------RVRHPYIVHLFEVMAT--KSKIYFVMEYVGGGEL----- 159
Query: 188 SKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYH 247
+ + +G+L EE A + + + + + G+G+ HRDLKP+N+LLD
Sbjct: 160 --------FNTVAKGRLP--EETARRYFQQLISSVSFCHGRGVYHRDLKPENLLLDN-KG 208
Query: 248 SLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQ 307
+L++SDFG S + +DG + GTP + APE+
Sbjct: 209 NLKVSDFGLSAVAEQLR--QDGL--------CHTFCGTPAYIAPEVLT-------RKGYD 251
Query: 308 PFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIYGWIHEYVVN 367
K DVWS G+ ++ ++ +PF+ + Y I + + SS++ ++
Sbjct: 252 AAKADVWSCGVILFVLMAGHIPFYDKNIMVMYKKIYKGEFRCPRWFSSDLV-----RLLT 306
Query: 368 RMLSKNTASRPTTSNILR 385
R+L N +R T I++
Sbjct: 307 RLLDTNPDTRITIPEIMK 324
>Hs8923922 [R] KOG0586 Serine/threonine protein kinase
Length = 795
Score = 78.2 bits (191), Expect = 2e-14
Identities = 83/321 (25%), Positives = 143/321 (43%), Gaps = 69/321 (21%)
Query: 67 QKFVNQYRIGERLGCGQFGTVYKGH--TTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYE 124
Q + YR+ + +G G F V TG+ VA+K I K +N P S+ + +
Sbjct: 54 QPHIGNYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLN-PTSLQKLFR------ 106
Query: 125 SISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQW 184
E+ + KI LNHPN+++L E +++ + ++L+ A GE+
Sbjct: 107 ---------EVRIMKI---------LNHPNIVKLFEVIETEKT--LYLVMEYASGGEV-- 144
Query: 185 SRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDP 244
FD + G++ E A I + +QY + I+HRDLK +N+LLD
Sbjct: 145 -----FDYLVA-----HGRMKEKEARAK--FRQIVSAVQYCHQKYIVHRDLKAENLLLDG 192
Query: 245 VYHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHAS 304
+ ++I+DFG S F G D F G+P + APEL +G +
Sbjct: 193 DMN-IKIADFGFSN------EFTVGNKLDTF-------CGSPPYAAPELF---QGKKYDG 235
Query: 305 NEQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIYGWIHEY 364
E +DVWSLG+ +Y ++ LPF G+ + + + + + S++ E
Sbjct: 236 PE----VDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDC-----EN 286
Query: 365 VVNRMLSKNTASRPTTSNILR 385
++ ++L N R + I++
Sbjct: 287 LLKKLLVLNPIKRGSLEQIMK 307
>Hs16950621 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 992
Score = 78.2 bits (191), Expect = 2e-14
Identities = 71/275 (25%), Positives = 127/275 (45%), Gaps = 66/275 (24%)
Query: 67 QKFVNQYRIGERLGCGQFGTVYKGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESI 126
QK + Y I ERLG G+FG V++ +++ +K F K Y +
Sbjct: 536 QKVSDFYDIEERLGSGKFGQVFR--------LVEKKTRKVWAGKF--------FKAYSA- 578
Query: 127 SGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVL--GELQW 184
IR E + + L+HP ++Q C+D+ + ++ ++ L ++ GEL
Sbjct: 579 --------KEKENIRQEISIMNCLHHPKLVQ---CVDA-FEEKANIVMVLEIVSGGEL-- 624
Query: 185 SRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNIL-LD 243
++ + E +K + IS G++Y+ QGI+H DLKP+NI+ ++
Sbjct: 625 -----------FERIIDEDFELTERECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVN 673
Query: 244 PVYHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHA 303
+++ DFG + + + G L+ LF GTP F APE+ N+ E +A
Sbjct: 674 KTGTRIKLIDFGLARRLENA-----GSLKVLF--------GTPEFVAPEVINY-EPIGYA 719
Query: 304 SNEQPFKIDVWSLGITVYAILYNVLPFWGETEFDT 338
+ D+WS+G+ Y ++ + PF G+ + +T
Sbjct: 720 T-------DMWSIGVICYILVSGLSPFMGDNDNET 747
>Hs16950613 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 1845
Score = 78.2 bits (191), Expect = 2e-14
Identities = 71/275 (25%), Positives = 127/275 (45%), Gaps = 66/275 (24%)
Query: 67 QKFVNQYRIGERLGCGQFGTVYKGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESI 126
QK + Y I ERLG G+FG V++ +++ +K F K Y +
Sbjct: 1389 QKVSDFYDIEERLGSGKFGQVFR--------LVEKKTRKVWAGKF--------FKAYSA- 1431
Query: 127 SGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVL--GELQW 184
IR E + + L+HP ++Q C+D+ + ++ ++ L ++ GEL
Sbjct: 1432 --------KEKENIRQEISIMNCLHHPKLVQ---CVDA-FEEKANIVMVLEIVSGGEL-- 1477
Query: 185 SRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNIL-LD 243
++ + E +K + IS G++Y+ QGI+H DLKP+NI+ ++
Sbjct: 1478 -----------FERIIDEDFELTERECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVN 1526
Query: 244 PVYHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHA 303
+++ DFG + + + G L+ LF GTP F APE+ N+ E +A
Sbjct: 1527 KTGTRIKLIDFGLARRLENA-----GSLKVLF--------GTPEFVAPEVINY-EPIGYA 1572
Query: 304 SNEQPFKIDVWSLGITVYAILYNVLPFWGETEFDT 338
+ D+WS+G+ Y ++ + PF G+ + +T
Sbjct: 1573 T-------DMWSIGVICYILVSGLSPFMGDNDNET 1600
>Hs16950611 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 1914
Score = 78.2 bits (191), Expect = 2e-14
Identities = 71/275 (25%), Positives = 127/275 (45%), Gaps = 66/275 (24%)
Query: 67 QKFVNQYRIGERLGCGQFGTVYKGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESI 126
QK + Y I ERLG G+FG V++ +++ +K F K Y +
Sbjct: 1458 QKVSDFYDIEERLGSGKFGQVFR--------LVEKKTRKVWAGKF--------FKAYSA- 1500
Query: 127 SGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVL--GELQW 184
IR E + + L+HP ++Q C+D+ + ++ ++ L ++ GEL
Sbjct: 1501 --------KEKENIRQEISIMNCLHHPKLVQ---CVDA-FEEKANIVMVLEIVSGGEL-- 1546
Query: 185 SRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNIL-LD 243
++ + E +K + IS G++Y+ QGI+H DLKP+NI+ ++
Sbjct: 1547 -----------FERIIDEDFELTERECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVN 1595
Query: 244 PVYHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHA 303
+++ DFG + + + G L+ LF GTP F APE+ N+ E +A
Sbjct: 1596 KTGTRIKLIDFGLARRLENA-----GSLKVLF--------GTPEFVAPEVINY-EPIGYA 1641
Query: 304 SNEQPFKIDVWSLGITVYAILYNVLPFWGETEFDT 338
+ D+WS+G+ Y ++ + PF G+ + +T
Sbjct: 1642 T-------DMWSIGVICYILVSGLSPFMGDNDNET 1669
>Hs16950601 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 991
Score = 78.2 bits (191), Expect = 2e-14
Identities = 71/275 (25%), Positives = 127/275 (45%), Gaps = 66/275 (24%)
Query: 67 QKFVNQYRIGERLGCGQFGTVYKGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESI 126
QK + Y I ERLG G+FG V++ +++ +K F K Y +
Sbjct: 536 QKVSDFYDIEERLGSGKFGQVFR--------LVEKKTRKVWAGKF--------FKAYSA- 578
Query: 127 SGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVL--GELQW 184
IR E + + L+HP ++Q C+D+ + ++ ++ L ++ GEL
Sbjct: 579 --------KEKENIRQEISIMNCLHHPKLVQ---CVDA-FEEKANIVMVLEIVSGGEL-- 624
Query: 185 SRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNIL-LD 243
++ + E +K + IS G++Y+ QGI+H DLKP+NI+ ++
Sbjct: 625 -----------FERIIDEDFELTERECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVN 673
Query: 244 PVYHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHA 303
+++ DFG + + + G L+ LF GTP F APE+ N+ E +A
Sbjct: 674 KTGTRIKLIDFGLARRLENA-----GSLKVLF--------GTPEFVAPEVINY-EPIGYA 719
Query: 304 SNEQPFKIDVWSLGITVYAILYNVLPFWGETEFDT 338
+ D+WS+G+ Y ++ + PF G+ + +T
Sbjct: 720 T-------DMWSIGVICYILVSGLSPFMGDNDNET 747
>CE27768 [R] KOG0586 Serine/threonine protein kinase
Length = 1096
Score = 78.2 bits (191), Expect = 2e-14
Identities = 83/318 (26%), Positives = 143/318 (44%), Gaps = 69/318 (21%)
Query: 70 VNQYRIGERLGCGQFGTVY--KGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESIS 127
V +Y++ + +G G F V K TG VAIK I K +N P S+ + + +K
Sbjct: 119 VGKYKLLKTIGKGNFAKVKLAKHVITGHEVAIKIIDKTALN-PSSLQKLFREVK------ 171
Query: 128 GDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRE 187
+ +L+HPN+++L + +++ + ++L+ A GE+
Sbjct: 172 ------------------IMKQLDHPNIVKLYQVMETEQT--LYLVLEYASGGEV----- 206
Query: 188 SKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYH 247
FD + G++ E A I + +QYL + IIHRDLK +N+LLD
Sbjct: 207 --FDYLVA-----HGRMKEKEARAK--FRQIVSAVQYLHSKNIIHRDLKAENLLLDQDM- 256
Query: 248 SLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQ 307
+++I+DFG S F G D F G+P + APEL + G + E
Sbjct: 257 NIKIADFGFS------NTFSLGNKLDTF-------CGSPPYAAPELFS---GKKYDGPE- 299
Query: 308 PFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIYGWIHEYVVN 367
+DVWSLG+ +Y ++ LPF G+ + + + + + S++ E ++
Sbjct: 300 ---VDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDC-----ENLLK 351
Query: 368 RMLSKNTASRPTTSNILR 385
+ L N R + NI++
Sbjct: 352 KFLVINPQRRSSLDNIMK 369
>CE26212 [T] KOG0582 Ste20-like serine/threonine protein kinase
Length = 545
Score = 78.2 bits (191), Expect = 2e-14
Identities = 79/318 (24%), Positives = 130/318 (40%), Gaps = 48/318 (15%)
Query: 73 YRIGERLGCGQFGTVYKGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISGDVLI 132
Y++ E +G G TV+ Y P N ++ I ++
Sbjct: 57 YKLDESIGVGATATVFTA------------YCLPRNEKVAIKCI------------NLEK 92
Query: 133 MEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESKFDL 192
+ +V ++ E S+ NHPNV+ + +++W++ L G + + K
Sbjct: 93 CQTSVDELSHEIQAMSQCNHPNVVSYYTSFIA--QEELWVVMRLLNCGSMLDILKRKVKA 150
Query: 193 IEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYHSLRIS 252
I + ++ + G LD V VL ++ GL+Y G IHRD+K NILL +++I+
Sbjct: 151 IGKEQAQF-GVLDEVS--IATVLREVLKGLEYFHLNGQIHRDIKAGNILLAD-DGTIQIA 206
Query: 253 DFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQPFKID 312
DFG V L G L +K + VGTP + APE+ +G FK D
Sbjct: 207 DFG----VSGWLASSGGDLSR--QKVRHTFVGTPCWMAPEVMEQVQG-------YDFKAD 253
Query: 313 VWSLGITVYAILYNVLPFWGETEFDTYNLICHR-----QLKPDVHNSSNIYGWIHEYVVN 367
+WSLGI + P+ L + + + YG + ++
Sbjct: 254 IWSLGILAIELATGTAPYHKYPPMKVLMLTLQNDPPTLETNAERKDQYKAYGKSFKTLIR 313
Query: 368 RMLSKNTASRPTTSNILR 385
L K+ A RPT S +L+
Sbjct: 314 DCLQKDPAKRPTASELLK 331
>CE23838 [R] KOG0586 Serine/threonine protein kinase
Length = 1192
Score = 78.2 bits (191), Expect = 2e-14
Identities = 83/318 (26%), Positives = 143/318 (44%), Gaps = 69/318 (21%)
Query: 70 VNQYRIGERLGCGQFGTVY--KGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESIS 127
V +Y++ + +G G F V K TG VAIK I K +N P S+ + + +K
Sbjct: 167 VGKYKLLKTIGKGNFAKVKLAKHVITGHEVAIKIIDKTALN-PSSLQKLFREVK------ 219
Query: 128 GDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRE 187
+ +L+HPN+++L + +++ + ++L+ A GE+
Sbjct: 220 ------------------IMKQLDHPNIVKLYQVMETEQT--LYLVLEYASGGEV----- 254
Query: 188 SKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYH 247
FD + G++ E A I + +QYL + IIHRDLK +N+LLD
Sbjct: 255 --FDYLVA-----HGRMKEKEARAK--FRQIVSAVQYLHSKNIIHRDLKAENLLLDQDM- 304
Query: 248 SLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQ 307
+++I+DFG S F G D F G+P + APEL + G + E
Sbjct: 305 NIKIADFGFS------NTFSLGNKLDTF-------CGSPPYAAPELFS---GKKYDGPE- 347
Query: 308 PFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIYGWIHEYVVN 367
+DVWSLG+ +Y ++ LPF G+ + + + + + S++ E ++
Sbjct: 348 ---VDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDC-----ENLLK 399
Query: 368 RMLSKNTASRPTTSNILR 385
+ L N R + NI++
Sbjct: 400 KFLVINPQRRSSLDNIMK 417
>At5g04510 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 488
Score = 78.2 bits (191), Expect = 2e-14
Identities = 77/300 (25%), Positives = 133/300 (43%), Gaps = 53/300 (17%)
Query: 83 QFGTVYKGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISGDVLIMEMNVSKIRW 142
+FG +Y + KVV K KK + +++ ++ K + E + ++
Sbjct: 42 EFGKIYGVGSYSKVVRAK---KKETGTVYALKIMDKKF----------ITKENKTAYVKL 88
Query: 143 ECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESKFDLIEQWKSFYRG 202
E V +L HP +I+L S +++ GEL FD I + +G
Sbjct: 89 ERIVLDQLEHPGIIKLYFTFQDTSS--LYMALESCEGGEL-------FDQITR-----KG 134
Query: 203 QLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYHSLRISDFGCSLIVPS 262
+L E+ A ++ + L+Y+ G+IHRD+KP+N+LL H ++I+DFG S
Sbjct: 135 RLS--EDEARFYTAEVVDALEYIHSMGLIHRDIKPENLLLTSDGH-IKIADFG------S 185
Query: 263 KLPFKDGRLQDL----FEKELNKIVGTPLFTAPELCNFAEGSAHASNEQPFKIDVWSLGI 318
P +D ++ L + + VGT + PE+ N S+ F D+W+LG
Sbjct: 186 VKPMQDSQITVLPNAASDDKACTFVGTAAYVPPEVLN--------SSPATFGNDLWALGC 237
Query: 319 TVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIYGWIHEYVVNRMLSKNTASRP 378
T+Y +L PF +E+ + I R +K H S +++R+L + RP
Sbjct: 238 TLYQMLSGTSPFKDASEWLIFQRIIARDIKFPNHFSE-----AARDLIDRLLDTEPSRRP 292
>At3g61960 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 648
Score = 78.2 bits (191), Expect = 2e-14
Identities = 75/287 (26%), Positives = 121/287 (42%), Gaps = 69/287 (24%)
Query: 68 KFVNQYRIGERLGCGQFGTVY--KGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYES 125
+ V Y +G R+G G F V+ K ++G VA+K+I KK ++ +L+
Sbjct: 5 RLVGDYALGPRIGSGSFAVVWLAKHRSSGLEVAVKEIDKKLLSPKVRDNLLK-------- 56
Query: 126 ISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWS 185
E + S ++HPN+I+ E +++ D+I+L+ G+L
Sbjct: 57 -----------------EISILSTIDHPNIIRFYEAIET--GDRIFLVLEYCSGGDL--- 94
Query: 186 RESKFDLIEQWKSFYRGQLDSVEEFAVK-VLGDISNGLQYLQGQGIIHRDLKPQNILLD- 243
+ Y + V E K + ++ GLQ LQ + IHRDLKPQN+LL
Sbjct: 95 ------------AGYINRHGKVPEAVAKHFMRQLALGLQVLQEKHFIHRDLKPQNLLLSS 142
Query: 244 -PVYHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAH 302
V L+I DFG S P E G+PL+ APE+
Sbjct: 143 KEVTPLLKIGDFG---FARSLTP----------ESMAETFCGSPLYMAPEIIR------- 182
Query: 303 ASNEQPFKIDVWSLGITVYAILYNVLPFWGETEFDTY-NLICHRQLK 348
+ + K D+WS G ++ ++ PF G + N++ +LK
Sbjct: 183 -NQKYDAKADLWSAGAILFQLVTGKPPFDGNNHIQLFHNIVRDTELK 228
>7292679 [G] KOG0599 Phosphorylase kinase gamma subunit
Length = 560
Score = 78.2 bits (191), Expect = 2e-14
Identities = 56/184 (30%), Positives = 92/184 (49%), Gaps = 36/184 (19%)
Query: 150 LNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESKFDLIEQWKSFYRGQLDSVEE 209
+ HP +I L + +S ++L+ L GEL FD + + E+
Sbjct: 85 MGHPYIIDLQDVFESDAF--VFLVFELCPKGEL-------FD-------YLTSVVTLSEK 128
Query: 210 FAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYHSLRISDFGCSLIVPSKLPFKDG 269
++ I G++Y+ + I+HRDLKP+NILLD H+++I+DFG +
Sbjct: 129 KTRTIMRQIFEGVEYIHAKSIVHRDLKPENILLDE-NHNVKITDFGFA-----------K 176
Query: 270 RLQDLFEKELNKIVGTPLFTAPEL--CNFAEGSAHASNEQPFKIDVWSLGITVYAILYNV 327
+LQ+ ++L + GTP + APE CN EGS S E +D+W+ G+ ++ +L
Sbjct: 177 QLQE--GEKLTNLCGTPGYLAPETLKCNMFEGSPGYSQE----VDIWACGVIMFTLLVGC 230
Query: 328 LPFW 331
PFW
Sbjct: 231 PPFW 234
>YPL209c [D] KOG0580 Serine/threonine protein kinase
Length = 367
Score = 77.8 bits (190), Expect = 3e-14
Identities = 70/282 (24%), Positives = 122/282 (42%), Gaps = 66/282 (23%)
Query: 70 VNQYRIGERLGCGQFGTVY--KGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESIS 127
++ + +G++LG G+FG VY + +TG + A+K + K+
Sbjct: 101 LDDFELGKKLGKGKFGKVYCVRHRSTGYICALKVMEKEE--------------------- 139
Query: 128 GDVLIMEMNVSK-IRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSR 186
I++ N+ K R E + + LNHPN+ + +++L+ V GE+
Sbjct: 140 ----IIKYNLQKQFRREVEIQTSLNHPNLTKSYGYFHD--EKRVYLLMEYLVNGEM---- 189
Query: 187 ESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVY 246
+ L+ G + + A + I+N L Y+ + IIHRD+KP+NIL+
Sbjct: 190 ---YKLLR-----LHGPFNDI--LASDYIYQIANALDYMHKKNIIHRDIKPENILIG-FN 238
Query: 247 HSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNE 306
+ ++++DFG S+I P E + GT + +PE+ S E
Sbjct: 239 NVIKLTDFGWSIINPP-------------ENRRKTVCGTIDYLSPEMVE--------SRE 277
Query: 307 QPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLK 348
ID W+LG+ + +L PF E + TY I +K
Sbjct: 278 YDHTIDAWALGVLAFELLTGAPPFEEEMKDTTYKRIAALDIK 319
>HsM7657627 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 970
Score = 77.8 bits (190), Expect = 3e-14
Identities = 85/317 (26%), Positives = 137/317 (42%), Gaps = 67/317 (21%)
Query: 70 VNQYRIGERLGCGQFGTVYKGHT--TGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESIS 127
+ +++G LG G F VY+ + TG VAIK I KK M Y++
Sbjct: 9 IEDFKVGNLLGKGSFAGVYRAESIHTGLEVAIKMIDKKAM---------------YKA-- 51
Query: 128 GDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRE 187
V +++ E + +L HP++++L + S+ ++L+ + GE+ +
Sbjct: 52 -------GMVQRVKNEVKIHCQLKHPSILELYNYFED--SNYVYLVLEMCHNGEMNRYLK 102
Query: 188 SKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYH 247
++ K F E A + I G+ YL GI+HRDL N+LL
Sbjct: 103 NRV------KPF-------SENEARHFMHQIITGMLYLHSHGILHRDLTLSNLLLTR-NM 148
Query: 248 SLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQ 307
+++I+DFG L K+P EK + GTP + +PE+ A SAH
Sbjct: 149 NIKIADFG--LATQLKMP---------HEKHYT-LCGTPNYISPEI---ATRSAHG---- 189
Query: 308 PFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIYGWIHEYVVN 367
+ DVWSLG Y +L PF +T +T N + + S IH+
Sbjct: 190 -LESDVWSLGCMFYTLLIGRPPFDTDTVKNTLNKVVLADYEMPTFLSIEAKDLIHQ---- 244
Query: 368 RMLSKNTASRPTTSNIL 384
+L +N A R + S++L
Sbjct: 245 -LLRRNPADRLSLSSVL 260
>Hs4759178 [D] KOG0580 Serine/threonine protein kinase
Length = 344
Score = 77.8 bits (190), Expect = 3e-14
Identities = 73/283 (25%), Positives = 120/283 (41%), Gaps = 69/283 (24%)
Query: 70 VNQYRIGERLGCGQFGTVYKGHTTGK--VVAIKQIYKKPMNSPFSMSLIMKTMKRYESIS 127
++ + IG LG G+FG VY +VA+K ++K +
Sbjct: 74 IDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEK------------------ 115
Query: 128 GDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGEL--QWS 185
E ++R E + + L+HPN+++L +I+LI A GEL +
Sbjct: 116 ------EGVEHQLRREIEIQAHLHHPNILRLYNYFYD--RRRIYLILEYAPRGELYKELQ 167
Query: 186 RESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPV 245
+ FD E+ ++ ++++ L Y G+ +IHRD+KP+N+LL +
Sbjct: 168 KSCTFD----------------EQRTATIMEELADALMYCHGKKVIHRDIKPENLLLG-L 210
Query: 246 YHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASN 305
L+I+DFG S+ PS + GT + PE+ EG H N
Sbjct: 211 KGELKIADFGWSVHAPS--------------LRRKTMCGTLDYLPPEM---IEGRMH--N 251
Query: 306 EQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLK 348
E K+D+W +G+ Y +L PF + +TY I LK
Sbjct: 252 E---KVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLK 291
>At4g14580 [T] KOG0583 Serine/threonine protein kinase
Length = 426
Score = 77.8 bits (190), Expect = 3e-14
Identities = 84/326 (25%), Positives = 146/326 (44%), Gaps = 76/326 (23%)
Query: 70 VNQYRIGERLGCGQFGTVY--KGHTTGKVVAIKQIYK-KPMNSPFSMSLI--MKTMKRYE 124
+ +Y +G RLG G F V+ + +TG++VAIK I K K ++S +I ++ M+R
Sbjct: 18 LGKYELGRRLGSGSFAKVHVARSISTGELVAIKIIDKQKTIDSGMEPRIIREIEAMRRLH 77
Query: 125 SISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQW 184
NHPNV+++ E + + +I+L+ A GEL +
Sbjct: 78 --------------------------NHPNVLKIHEVMAT--KSKIYLVVEYAAGGEL-F 108
Query: 185 SRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDP 244
++ +F G+L+ E A + +++ L + GI HRD+KPQN+LLD
Sbjct: 109 TKLIRF-----------GRLN--ESAARRYFQQLASALSFCHRDGIAHRDVKPQNLLLDK 155
Query: 245 VYHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHAS 304
+L++SDFG S + + +G L+ GTP +TAPE+ A+ +
Sbjct: 156 -QGNLKVSDFGLSALPEHR--SNNGL--------LHTACGTPAYTAPEV--IAQRGYDGA 202
Query: 305 NEQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIYGWIHE- 363
K D WS G+ ++ +L +PF Y I R + WI +
Sbjct: 203 -----KADAWSCGVFLFVLLAGYVPFDDANIVAMYRKIHKRDYR--------FPSWISKP 249
Query: 364 --YVVNRMLSKNTASRPTTSNILRTL 387
++ ++L N +R + ++ T+
Sbjct: 250 ARSIIYKLLDPNPETRMSIEAVMGTV 275
>At3g06030 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 651
Score = 77.8 bits (190), Expect = 3e-14
Identities = 72/275 (26%), Positives = 117/275 (42%), Gaps = 58/275 (21%)
Query: 72 QYRIGERLGCGQFGTVYKGHT--TGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISGD 129
++R GE +GCG FG VY G +G+++AIKQ+ LI + E G
Sbjct: 67 RWRKGELIGCGAFGRVYMGMNLDSGELLAIKQV------------LIAPSSASKEKTQGH 114
Query: 130 VLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESK 189
+ +E V ++ L+HPN+++ L + SD + ++ G +
Sbjct: 115 IRELEEEVQLLK-------NLSHPNIVRYLGTVRE--SDSLNILMEFVPGGSIS------ 159
Query: 190 FDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYHSL 249
L+E++ SF E + + GL+YL GI+HRD+K NIL+D +
Sbjct: 160 -SLLEKFGSF-------PEPVIIMYTKQLLLGLEYLHNNGIMHRDIKGANILVDN-KGCI 210
Query: 250 RISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQPF 309
R++DFG S V + + GTP + APE+ F
Sbjct: 211 RLADFGASKKVVELATVNGAK----------SMKGTPYWMAPEVI--------LQTGHSF 252
Query: 310 KIDVWSLGITVYAILYNVLPFWGETEFDTYNLICH 344
D+WS+G TV + P W E ++ + + H
Sbjct: 253 SADIWSVGCTVIEMATGKPP-WSE-QYQQFAAVLH 285
>SPCC1322.08 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 580
Score = 77.4 bits (189), Expect = 4e-14
Identities = 81/347 (23%), Positives = 151/347 (43%), Gaps = 70/347 (20%)
Query: 10 FPESIRIQPMSTDPESYFQIIDEQQKKLELGVISKTKIIERYVXXXXXXXXXQEEHAQKF 69
F E++ P Q +E++ + + I+E + Q+ K
Sbjct: 69 FHETVHENPSEYSRSKCKQPTNEKEYDKAIEALVAKAIVEEH--------SGQQFPVYKG 120
Query: 70 VNQYRIGERLGCGQFGTVYKG--HTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESIS 127
+ QY + +++G G F VYK + TG+ VAIK + + N+ + ++ + +
Sbjct: 121 LEQYTLLQKMGDGAFSNVYKAIHNRTGEKVAIKVVQRAQPNTD------PRDPRKRQGVE 174
Query: 128 GDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRE 187
++ E+ + + ++ HPN+IQLLE + +P + +L+ LA GEL
Sbjct: 175 SHNILKEVQIMR---------RVKHPNIIQLLEFIQTP--EYYYLVLELADGGEL----- 218
Query: 188 SKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQ-GIIHRDLKPQNILLDPV- 245
F I + F E+ + V+ +++ ++YL G++HRD+KP+N+L D +
Sbjct: 219 --FHQIVRLTYFS-------EDLSRHVITQVAHAIRYLHEDCGVVHRDIKPENLLFDSID 269
Query: 246 YHSLRISDFGC---------SLIVPSKLPFKDGRLQDLFEKELNKIV---------GTPL 287
+ R+ + +P GR++ L + L+K+V GT
Sbjct: 270 FVPSRVRKYRAGDDPDKVDEGEFIPGVGAGTIGRIR-LADFGLSKVVWDSHTQTPCGTMG 328
Query: 288 FTAPELCNFAEGSAHASNEQPFKIDVWSLGITVYAILYNVLPFWGET 334
+TAPE+ S +D+W+LG +Y IL PF+ E+
Sbjct: 329 YTAPEIVRDERYSK--------GVDMWALGCVLYTILCGFPPFYDES 367
>Hs9966875 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 357
Score = 77.4 bits (189), Expect = 4e-14
Identities = 82/331 (24%), Positives = 137/331 (40%), Gaps = 76/331 (22%)
Query: 63 EEHAQKFVNQYRIGERLGCGQFGTVYKGH--TTGKVVAIKQIYKKPMNSPFSMSLIMKTM 120
++ A+ + E LG G F V TGK+ A+K I KK + S
Sbjct: 13 KKQAEDIKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKES-------- 64
Query: 121 KRYESISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLG 180
SI ++ ++ K+ H N++ L + +SP + ++L+ L G
Sbjct: 65 ----SIENEIAVLR--------------KIKHENIVALEDIYESP--NHLYLVMQLVSGG 104
Query: 181 ELQWSRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNI 240
EL FD I + K FY E+ A ++ + + + YL GI+HRDLKP+N+
Sbjct: 105 EL-------FDRIVE-KGFY------TEKDASTLIRQVLDAVYYLHRMGIVHRDLKPENL 150
Query: 241 LLDPVYHS------LRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELC 294
L Y+S + ISDFG S + +G+ ++ GTP + APE+
Sbjct: 151 L----YYSQDEESKIMISDFGLSKM--------EGK-----GDVMSTACGTPGYVAPEVL 193
Query: 295 NFAEGSAHASNEQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNS 354
A +D WS+G+ Y +L PF+ E + + I + + D
Sbjct: 194 --------AQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYW 245
Query: 355 SNIYGWIHEYVVNRMLSKNTASRPTTSNILR 385
+I +++ N ++ K+ R T R
Sbjct: 246 DDISDSAKDFIRN-LMEKDPNKRYTCEQAAR 275
>Hs13899225 [R] KOG0586 Serine/threonine protein kinase
Length = 688
Score = 77.4 bits (189), Expect = 4e-14
Identities = 79/321 (24%), Positives = 137/321 (42%), Gaps = 69/321 (21%)
Query: 67 QKFVNQYRIGERLGCGQFGTVYKGH--TTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYE 124
Q V YR+ +G G V TG+ VAIK I K +N P S+ + + ++
Sbjct: 53 QPHVGNYRLLRTIGKGNSAKVKLARHILTGREVAIKIIDKTQLN-PSSLQKLFREVR--- 108
Query: 125 SISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQW 184
+ LNHPN+++L E +++ + ++L+ A GE+
Sbjct: 109 ---------------------IMKGLNHPNIVKLFEVIETEKT--LYLVMEYASAGEV-- 143
Query: 185 SRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDP 244
FD + G++ E A I + + Y + I+HRDLK +N+LLD
Sbjct: 144 -----FDYLVS-----HGRMKEKEARAK--FRQIVSAVHYCHQKNIVHRDLKAENLLLD- 190
Query: 245 VYHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHAS 304
+++I+DFG S + +L+ G+P + APEL +G +
Sbjct: 191 AEANIKIADFGFS-------------NEFTLGSKLDTFCGSPPYAAPEL---FQGKKYDG 234
Query: 305 NEQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIYGWIHEY 364
E +D+WSLG+ +Y ++ LPF G + + + + + S++ E
Sbjct: 235 PE----VDIWSLGVILYTLVSGSLPFDGHNLKELRERVLRGKYRVPFYMSTDC-----ES 285
Query: 365 VVNRMLSKNTASRPTTSNILR 385
++ R L N A R T I++
Sbjct: 286 ILRRFLVLNPAKRCTLEQIMK 306
>SPCC63.08c [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 830
Score = 77.0 bits (188), Expect = 6e-14
Identities = 72/279 (25%), Positives = 127/279 (44%), Gaps = 58/279 (20%)
Query: 70 VNQYRIGERLGCGQFGTVYKG-HT-TGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESIS 127
+ Y I +G G F VYKG HT T +V++IK + K + T K E++
Sbjct: 11 IGPYVIRSEIGRGSFAIVYKGKHTETNRVISIKSVLTKKL-----------TKKLLENLE 59
Query: 128 GDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQW--S 185
++ I++ ++ H +V++L++C+ + I L+ LG+L +
Sbjct: 60 SEISILK--------------EIRHVHVVELIDCIKA--GRFIHLVMEYCSLGDLSYFIR 103
Query: 186 RESKFDLIEQ--WKSF-----YRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQ 238
+ KF+ I W + Y+ L+ E +++ LQ+L+ + +IHRD+KPQ
Sbjct: 104 KREKFNSIPSLAWINIDHPPVYKAGLN--ETLVRHFTQQLASALQFLRSRSLIHRDVKPQ 161
Query: 239 NILLDPVYHSLRISDFGCSLIVPSKLPFKDGRLQDL-FEKEL------NKIVGTPLFTAP 291
N+LL P + + + + KLP +L D F + L + G+PL+ AP
Sbjct: 162 NLLLQPPPTAAYLEEHP-QFVGSPKLPML--KLADFGFARYLQTSSMAETLCGSPLYMAP 218
Query: 292 ELCNFAEGSAHASNEQPFKIDVWSLGITVYAILYNVLPF 330
E+ + + A K D+WS+G +Y + PF
Sbjct: 219 EILRYEKYDA--------KADLWSVGAVLYEMAVGKPPF 249
>SPCC1919.01 [T] KOG0583 Serine/threonine protein kinase
Length = 203
Score = 77.0 bits (188), Expect = 6e-14
Identities = 55/164 (33%), Positives = 83/164 (50%), Gaps = 24/164 (14%)
Query: 222 LQYLQGQGIIHRDLKPQNILLDPVYHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNK 281
+ Y+ G+G+IHRD+KP NIL ++L + DFG + +P KDG F K +
Sbjct: 37 VNYIHGKGVIHRDIKPDNILFKE-NNNLCVIDFGLAEFLP-----KDG-----FVKPAS- 84
Query: 282 IVGTPLFTAPELCNFAEGSAHASNEQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNL 341
GTP F APEL + +P +D+WS+G+T+Y I + PF G T D N+
Sbjct: 85 --GTPAFMAPELF---DNELKKIKGKP--LDIWSMGVTLYVIAFAEFPFNGSTILDMINV 137
Query: 342 ICHRQLKPDVHNSSNIYGWIHEYVVNRMLSKNTASRPTTSNILR 385
I + L + +S++ ++ R L KN R T +LR
Sbjct: 138 IKGKSLMIPAYCNSDL-----RKLLERCLEKNPEKRITIEELLR 176
>Hs4758194 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 372
Score = 77.0 bits (188), Expect = 6e-14
Identities = 75/288 (26%), Positives = 123/288 (42%), Gaps = 48/288 (16%)
Query: 94 GKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISGDVLIMEMNVSKIRWECFVTSKLNHP 153
GK ++Q K ++ + K +R + ++L E+ V ++ C P
Sbjct: 42 GKFAVVRQCISKSTGQEYAAKFLKKR-RRGQDCRAEIL-HEIAVLELAKSC--------P 91
Query: 154 NVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESKFDLIEQWKSFYRGQLDSVEEFAVK 213
VI L E ++ + +I LI A GE+ F L + + D ++
Sbjct: 92 RVINLHEVYEN--TSEIILILEYAAGGEI-------FSLCLPELAEMVSEND-----VIR 137
Query: 214 VLGDISNGLQYLQGQGIIHRDLKPQNILLDPVY--HSLRISDFGCSLIVPSKLPFKDGRL 271
++ I G+ YL I+H DLKPQNILL +Y ++I DFG S +
Sbjct: 138 LIKQILEGVYYLHQNNIVHLDLKPQNILLSSIYPLGDIKIVDFGMSRKIGHAC------- 190
Query: 272 QDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQPFKIDVWSLGITVYAILYNVLPFW 331
EL +I+GTP + APE+ N+ + D+W++GI Y +L + PF
Sbjct: 191 ------ELREIMGTPEYLAPEILNY--------DPITTATDMWNIGIIAYMLLTHTSPFV 236
Query: 332 GETEFDTYNLICHRQLKPDVHNSSNIYGWIHEYVVNRMLSKNTASRPT 379
GE +TY I + S++ ++ + +L KN RPT
Sbjct: 237 GEDNQETYLNISQVNVDYSEETFSSVSQLATDF-IQSLLVKNPEKRPT 283
>CE09360 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 2783
Score = 77.0 bits (188), Expect = 6e-14
Identities = 79/319 (24%), Positives = 137/319 (42%), Gaps = 71/319 (22%)
Query: 72 QYRIGERLGCGQFGTVYKG--HTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISGD 129
+Y I E LG G +GTVY+ TGK A K + +P + +
Sbjct: 194 KYIIHEELGKGAYGTVYRATEKATGKTWAAKMVQVRP------------------GVKKE 235
Query: 130 VLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESK 189
+I E+++ ++L+H ++ L E D +++WLI+ GEL
Sbjct: 236 NVIHEISMM---------NQLHHEKLLNLHEAFDM--GNEMWLIEEFVSGGEL------- 277
Query: 190 FDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVY-HS 248
F+ I + S EE + I G+ ++ I+H DLKP+NILL +
Sbjct: 278 FEKILEDDSLMS------EEEVRDYMHQILLGVSHMHKNQIVHLDLKPENILLKAKNSNE 331
Query: 249 LRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQP 308
L+I DFG + + K K + + GTP F APE+ N+ QP
Sbjct: 332 LKIIDFGLARKLDPK-------------KSVKLLFGTPEFCAPEVVNY----------QP 368
Query: 309 FKI--DVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIYGWIHEYVV 366
+ D+W++G+ Y +L + PF G+++ DT + D + ++ +++
Sbjct: 369 VGLSTDMWTVGVISYVLLSGLSPFLGDSDEDTLANVSASDWDFDDPSWDDVSDLAKDFIC 428
Query: 367 NRMLSKNTASRPTTSNILR 385
R++ K+ R + + LR
Sbjct: 429 -RLMIKDKRKRMSVQDALR 446
>At5g39440 [T] KOG0583 Serine/threonine protein kinase
Length = 494
Score = 77.0 bits (188), Expect = 6e-14
Identities = 73/260 (28%), Positives = 120/260 (46%), Gaps = 64/260 (24%)
Query: 73 YRIGERLGCGQFGTVYKGH--TTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISGDV 130
YRIG+ LG G F V TG VAIK + + + +
Sbjct: 19 YRIGKTLGHGSFAKVKLALHVATGHKVAIKILNRSKIKN--------------------- 57
Query: 131 LIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESKF 190
M + + K++ E + L HP++I+ E +++P + I+++ GEL F
Sbjct: 58 --MGIEI-KVQREIKILRFLMHPHIIRQYEVIETP--NDIYVVMEYVKSGEL-------F 105
Query: 191 DLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYHSLR 250
D I + +G+L E+ A + I +G++Y I+HRDLKP+N+LLD +++
Sbjct: 106 DYIVE-----KGKLQ--EDEARHLFQQIISGVEYCHRNMIVHRDLKPENVLLDS-QCNIK 157
Query: 251 ISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQPFK 310
I DFG S ++ DG L G+P + APE+ + G + +
Sbjct: 158 IVDFGLSNVM------HDGHF-------LKTSCGSPNYAAPEVIS---GKPYGPD----- 196
Query: 311 IDVWSLGITVYAILYNVLPF 330
+D+WS G+ +YA+L LPF
Sbjct: 197 VDIWSCGVILYALLCGTLPF 216
>7290313 [T] KOG0193 Serine/threonine protein kinase RAF
Length = 739
Score = 77.0 bits (188), Expect = 6e-14
Identities = 80/294 (27%), Positives = 123/294 (41%), Gaps = 67/294 (22%)
Query: 63 EEHAQKFVNQYRIGERLGCGQFGTVYKGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKR 122
EE+ + IG R+G G FGTVY+ H G V K P SP +
Sbjct: 419 EENWNILAEEILIGPRIGSGSFGTVYRAHWHGPVAVKTLNVKTP--SPAQL--------- 467
Query: 123 YESISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGEL 182
++ +V +++ K H N++ + C+ P LA++
Sbjct: 468 -QAFKNEVAMLK--------------KTRHCNILLFMGCVSKP---------SLAIV--T 501
Query: 183 QWSRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDI----SNGLQYLQGQGIIHRDLKPQ 238
QW S S Y+ S +F + L DI + G+ YL + IIHRDLK
Sbjct: 502 QWCEGS---------SLYKHVHVSETKFKLNTLIDIGRQVAQGMDYLHAKNIIHRDLKSN 552
Query: 239 NILLDPVYHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAE 298
NI L S++I DFG + +K + EK+ N+ G+ L+ APE+ E
Sbjct: 553 NIFLHEDL-SVKIGDFG---LATAKTRWSG-------EKQANQPTGSILWMAPEVIRMQE 601
Query: 299 GSAHASNEQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHR-QLKPDV 351
N F+ DV++ GI +Y +L LP+ + D + R L+PD+
Sbjct: 602 -----LNPYSFQSDVYAFGIVMYELLAECLPYGHISNKDQILFMVGRGLLRPDM 650
>YMR001c [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 705
Score = 76.6 bits (187), Expect = 7e-14
Identities = 76/313 (24%), Positives = 132/313 (41%), Gaps = 63/313 (20%)
Query: 73 YRIGERLGCGQFGTVYK-GHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISGDVL 131
Y G LG G F ++ +G++ A K + K + S KT K+ L
Sbjct: 82 YHRGHFLGEGGFARCFQIKDDSGEIFAAKTVAKASIKSE-------KTRKK--------L 126
Query: 132 IMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESKFD 191
+ E+ + K ++HPN++Q ++C + ++++ + G L + +
Sbjct: 127 LSEIQIHK---------SMSHPNIVQFIDCFED--DSNVYILLEICPNGSLMELLKRRKV 175
Query: 192 LIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYHSLRI 251
L E F+ Q I ++Y+ + +IHRDLK NI D Y+ L+I
Sbjct: 176 LTEPEVRFFTTQ--------------ICGAIKYMHSRRVIHRDLKLGNIFFDSNYN-LKI 220
Query: 252 SDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQPFKI 311
DFG + ++ ++ K I GTP + APE+ + S H+ F++
Sbjct: 221 GDFGLAAVLANESERK------------YTICGTPNYIAPEVL-MGKHSGHS-----FEV 262
Query: 312 DVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIYGWIHEYVVNRMLS 371
D+WSLG+ +YA+L PF Y I R + G I ++ +LS
Sbjct: 263 DIWSLGVMLYALLIGKPPFQARDVNTIYERIKCRDFSFPRDKPISDEGKI---LIRDILS 319
Query: 372 KNTASRPTTSNIL 384
+ RP+ + I+
Sbjct: 320 LDPIERPSLTEIM 332
>At5g24430 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 594
Score = 76.6 bits (187), Expect = 7e-14
Identities = 74/325 (22%), Positives = 135/325 (40%), Gaps = 68/325 (20%)
Query: 67 QKFVNQYRIGERLGCGQFG-----TVYKGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMK 121
+ F +Y +G+ +G G FG KG + VA+K I K M S S+ + + +K
Sbjct: 137 KNFEGKYELGKEVGRGHFGHTCWAKAKKGKMKNQTVAVKIISKAKMTSTLSIEDVRREVK 196
Query: 122 RYESISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGE 181
+++SG H ++++ + + +D ++++ L GE
Sbjct: 197 LLKALSG-----------------------HRHMVKFYDVYED--ADNVFVVMELCEGGE 231
Query: 182 LQWSRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNIL 241
L D I Y E A ++L I + + QG++HRDLKP+N L
Sbjct: 232 L-------LDRILARGGRYP------EVDAKRILVQILSATAFFHLQGVVHRDLKPENFL 278
Query: 242 LDPVYHS--LRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEG 299
L++ DFG S + +++ LN +VG+ + APE+ + +
Sbjct: 279 FTSRNEDAILKVIDFGLSDFI-------------RYDQRLNDVVGSAYYVAPEVLHRSYS 325
Query: 300 SAHASNEQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIYG 359
+ + D+WS+G+ Y +L PF+G TE + + + +I
Sbjct: 326 T---------EADMWSIGVISYILLCGSRPFYGRTESAIFRCVLRANPNFEDMPWPSISP 376
Query: 360 WIHEYVVNRMLSKNTASRPTTSNIL 384
++ V R+L+K+ R T + L
Sbjct: 377 TAKDF-VKRLLNKDHRKRMTAAQAL 400
>At2g17290 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 544
Score = 76.3 bits (186), Expect = 9e-14
Identities = 83/319 (26%), Positives = 131/319 (41%), Gaps = 70/319 (21%)
Query: 73 YRIGERLGCGQFGTVY--KGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISGDV 130
Y + +LG GQFGT Y TG A K I K+
Sbjct: 85 YTLSRKLGQGQFGTTYLCTDIATGVDYACKSISKRK------------------------ 120
Query: 131 LIMEMNVSKIRWECFVTSKL-NHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESK 189
LI + +V +R E + L H N++ + + P + ++ L GEL
Sbjct: 121 LISKEDVEDVRREIQIMHHLAGHKNIVTIKGAYEDPL--YVHIVMELCAGGEL------- 171
Query: 190 FDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILL---DPVY 246
FD I +RG E A ++ I ++ G++HRDLKP+N LL D +
Sbjct: 172 FDRI-----IHRGHYS--ERKAAELTKIIVGVVEACHSLGVMHRDLKPENFLLVNKDDDF 224
Query: 247 HSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNE 306
SL+ DFG S+ FK G++ +VG+P + APE+ G
Sbjct: 225 -SLKAIDFGLSVF------FKPGQI-------FKDVVGSPYYVAPEVLLKHYGP------ 264
Query: 307 QPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIYGWIHEYVV 366
+ DVW+ G+ +Y +L V PFW ET+ ++ + + D I + ++
Sbjct: 265 ---EADVWTAGVILYILLSGVPPFWAETQQGIFDAVLKGYIDFDTDPWPVISDSAKD-LI 320
Query: 367 NRMLSKNTASRPTTSNILR 385
+ML + + R T +LR
Sbjct: 321 RKMLCSSPSERLTAHEVLR 339
>7299438 [R] KOG0586 Serine/threonine protein kinase
Length = 705
Score = 76.3 bits (186), Expect = 9e-14
Identities = 83/314 (26%), Positives = 140/314 (44%), Gaps = 69/314 (21%)
Query: 73 YRIGERLGCGQFGTVYKG-HT-TGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISGDV 130
Y+I + LG G F V H TG+ VAIK I K +N+ L +V
Sbjct: 98 YKIIKTLGKGNFAKVKLAIHVPTGREVAIKVIDKTQLNTSARQKLYR-----------EV 146
Query: 131 LIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESKF 190
IM++ LNHPN+++L + ++S + ++L+ A GEL F
Sbjct: 147 KIMKL--------------LNHPNIVRLFQVIESERT--LYLVMEYASRGEL-------F 183
Query: 191 DLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYHSLR 250
D + + G++ E A + + + +QY + ++HRDLK +N+LLD + +++
Sbjct: 184 DHLVK-----NGRMR--ERDARVIFRQLVSAIQYCHSKFVVHRDLKAENLLLDQ-HMNIK 235
Query: 251 ISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQPFK 310
I+DFG G D +L G+P + APEL G +A E
Sbjct: 236 IADFGF------------GNTFDP-NAQLETFCGSPPYAAPEL---FMGRKYAGPE---- 275
Query: 311 IDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIYGWIHEYVVNRML 370
+D WSLG+ +Y ++ LPF G T + + + + + S + E ++ + L
Sbjct: 276 VDAWSLGVVLYTLVSGSLPFDGGTLKELRERVLRGKYRVPYYISMDC-----ENLMRKFL 330
Query: 371 SKNTASRPTTSNIL 384
N A R + S ++
Sbjct: 331 VLNPAKRTSLSAVM 344
>Hs21361433 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 970
Score = 75.9 bits (185), Expect = 1e-13
Identities = 84/317 (26%), Positives = 137/317 (42%), Gaps = 67/317 (21%)
Query: 70 VNQYRIGERLGCGQFGTVYKGHT--TGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESIS 127
+ +++G LG G F VY+ + +G VAIK I KK M Y++
Sbjct: 9 IEDFKVGNLLGKGSFAGVYRAESIHSGLEVAIKMIDKKAM---------------YKA-- 51
Query: 128 GDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRE 187
V +++ E + +L HP++++L + S+ ++L+ + GE+ +
Sbjct: 52 -------GMVQRVQNEVKIHCQLKHPSILELYNYFED--SNYVYLVLEMCHNGEMNRYLK 102
Query: 188 SKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYH 247
++ K F E A + I G+ YL GI+HRDL N+LL
Sbjct: 103 NRV------KPF-------SENEARHFMHQIITGMLYLHSHGILHRDLTLSNLLLTR-NM 148
Query: 248 SLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQ 307
+++I+DFG L K+P EK + GTP + +PE+ A SAH
Sbjct: 149 NIKIADFG--LATQLKMP---------HEKHYT-LCGTPNYISPEI---ATRSAHG---- 189
Query: 308 PFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIYGWIHEYVVN 367
+ DVWSLG Y +L PF +T +T N + + S IH+
Sbjct: 190 -LESDVWSLGCMFYTLLIGRPPFDTDTVKNTLNKVVLADYEMPTFLSIEAKDLIHQ---- 244
Query: 368 RMLSKNTASRPTTSNIL 384
+L +N A R + S++L
Sbjct: 245 -LLRRNPADRLSLSSVL 260
>CE20167 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD and related
proteins
Length = 722
Score = 75.9 bits (185), Expect = 1e-13
Identities = 77/275 (28%), Positives = 122/275 (44%), Gaps = 68/275 (24%)
Query: 64 EHAQKFVNQYRI--GERLGCGQFGTVYKG--HTTGKVVAIKQIYKKPMNSPFSMSLIMKT 119
E A +F N Y++ + LG GQFGTVY +GK VA+K I K+ + S +
Sbjct: 415 EQALEFANLYQVLSDKTLGSGQFGTVYSAIQRHSGKEVAVKVISKERFSKKGSGA----- 469
Query: 120 MKRYESISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVL 179
ES+ +V I++ HP ++ L ++ D+I+++
Sbjct: 470 ----ESMRAEVAILQQTC--------------HPGIVCLEFMCET--KDKIFVVM----- 504
Query: 180 GELQWSRESKFDLIEQWKSFYRGQLDSVEEFAVK-VLGDISNGLQYLQGQGIIHRDLKPQ 238
+ D++E S G+L+S A K +L I L+YL QGI H DLKP+
Sbjct: 505 ------EKMNGDMLEMILSQELGRLNSR---ATKFLLVQILCALKYLHDQGIAHCDLKPE 555
Query: 239 NILLDPV---YHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCN 295
N+LL + + +I DFG + +P + F K +VGTP + PE+
Sbjct: 556 NVLLSDMGSNFPQTKICDFGYARFIP----------ESQFRK---TVVGTPAYLPPEVL- 601
Query: 296 FAEGSAHASNEQPFKIDVWSLGITVYAILYNVLPF 330
N+ +D+WS+G+ +Y L PF
Sbjct: 602 ----QRKGYNK---SLDMWSVGVIIYVTLSGTFPF 629
>At4g35310 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 556
Score = 75.9 bits (185), Expect = 1e-13
Identities = 88/324 (27%), Positives = 136/324 (41%), Gaps = 80/324 (24%)
Query: 73 YRIGERLGCGQFGTVY--KGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISGDV 130
Y + +LG GQFGT Y +G A K I K+
Sbjct: 97 YTLSRKLGQGQFGTTYLCTEIASGVDYACKSISKRK------------------------ 132
Query: 131 LIMEMNVSKIRWECFVTSKL-NHPNVIQLLECLDSPYSDQIW--LIQPLAVLGELQWSRE 187
LI + +V +R E + L H +++ + Y D ++ ++ L GEL
Sbjct: 133 LISKEDVEDVRREIQIMHHLAGHGSIV----TIKGAYEDSLYVHIVMELCAGGEL----- 183
Query: 188 SKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILL---DP 244
FD I Q RG E A ++ I ++ G++HRDLKP+N LL D
Sbjct: 184 --FDRIIQ-----RGHYS--ERKAAELTKIIVGVVEACHSLGVMHRDLKPENFLLVNKDD 234
Query: 245 VYHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHAS 304
+ SL+ DFG S+ FK G++ +VG+P + APE+ G
Sbjct: 235 DF-SLKAIDFGLSVF------FKPGQI-------FTDVVGSPYYVAPEVLLKRYGP---- 276
Query: 305 NEQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIYGWIHEY 364
+ DVW+ G+ +Y +L V PFW ET+ ++ + LK + S+ + I +
Sbjct: 277 -----EADVWTAGVILYILLSGVPPFWAETQQGIFDAV----LKGYIDFESDPWPVISDS 327
Query: 365 ---VVNRMLSKNTASRPTTSNILR 385
++ RMLS A R T +LR
Sbjct: 328 AKDLIRRMLSSKPAERLTAHEVLR 351
>YPL141c [T] KOG0583 Serine/threonine protein kinase
Length = 865
Score = 75.5 bits (184), Expect = 2e-13
Identities = 82/278 (29%), Positives = 119/278 (42%), Gaps = 64/278 (23%)
Query: 63 EEHAQKFVN--QYRIGERLGCGQFGTVYKGHTTGKVVAIKQIYKKPMNSPFSM--SLIMK 118
+E +K V Y +G LG G+FG V G + NS F + +K
Sbjct: 29 DEQRRKHVTFGPYILGSTLGEGEFGKVKLGWPKN--------FSNSSNSTFDFPKQVAIK 80
Query: 119 TMKRYESISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAV 178
+KR +SIS D KI E L+HPN+++L E L + S I ++ A
Sbjct: 81 LIKR-DSISNDY----RKEVKIYREINALKHLSHPNIVKLEEVLQN--SRYIGIVLEYAC 133
Query: 179 LGELQWSRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQ 238
GE + K L E A ++ + +G+ Y+ +G++HRDLK +
Sbjct: 134 GGEFYKYIQKKRRLKEM--------------NACRLFSQLISGVHYIHSKGLVHRDLKLE 179
Query: 239 NILLDPVYHSLRISDFG-----CSLIVPSKLPFKDGRLQDLFEKELNKI-VGTPLFTAPE 292
N+LLD +L I+DFG CS EL K G+P + APE
Sbjct: 180 NLLLDK-NENLVITDFGFVNEFCS------------------RNELMKTSCGSPCYAAPE 220
Query: 293 LCNFAEGSAHASNEQPFKIDVWSLGITVYAILYNVLPF 330
L AE + K D+WS G+ +YAIL LP+
Sbjct: 221 LVISAE------PYEARKADIWSCGVILYAILAGYLPW 252
>YNR047w [R] KOG0610 Putative serine/threonine protein kinase
Length = 893
Score = 75.5 bits (184), Expect = 2e-13
Identities = 67/263 (25%), Positives = 120/263 (45%), Gaps = 39/263 (14%)
Query: 126 ISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWS 185
+S D +I + ++ E + + NHP ++ L S D ++L + GE +
Sbjct: 527 LSKDEMIKRNKIKRVLTEQEILATSNHPFIVTLYHSFQS--EDYLYLCMEYCMGGEFFRA 584
Query: 186 RESKFD--LIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLD 243
+++ + E FY + ++ L+YL G I+RDLKP+NILL
Sbjct: 585 LQTRKTKCICEDDARFYASE--------------VTAALEYLHLLGFIYRDLKPENILLH 630
Query: 244 PVYHSLRISDFGCSL-IVPSKLPFKDGRLQD-LFEKEL-------NKIVGTPLFTAPELC 294
H + +SDF S+ SK+P G Q L + ++ N VGT + APE+
Sbjct: 631 QSGH-IMLSDFDLSIQAKDSKVPVVKGSAQSTLVDTKICSDGFRTNSFVGTEEYIAPEV- 688
Query: 295 NFAEGSAHASNEQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNS 354
G+ H + +D W+LGI +Y +L+ PF G+ +T+ I ++ +
Sbjct: 689 --IRGNGHTA-----AVDWWTLGILIYEMLFGFTPFKGDNTNETFTNILKNEVS---FPN 738
Query: 355 SNIYGWIHEYVVNRMLSKNTASR 377
+N + ++ ++L+KN + R
Sbjct: 739 NNEISRTCKDLIKKLLTKNESKR 761
>Hs4502553 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 370
Score = 75.5 bits (184), Expect = 2e-13
Identities = 86/330 (26%), Positives = 138/330 (41%), Gaps = 76/330 (23%)
Query: 64 EHAQKFVNQYRIGERLGCGQFGTVY--KGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMK 121
+ A+ + Y + LG G F V + T K+VAIK I K
Sbjct: 11 KQAEDIRDIYDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAK----------------- 53
Query: 122 RYESISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGE 181
E++ G ME ++ V K+ HPN++ L + +S ++LI L GE
Sbjct: 54 --EALEGKEGSMENEIA-------VLHKIKHPNIVALDDIYES--GGHLYLIMQLVSGGE 102
Query: 182 LQWSRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNIL 241
L FD I + K FY E A +++ + + ++YL GI+HRDLKP+N+L
Sbjct: 103 L-------FDRIVE-KGFY------TERDASRLIFQVLDAVKYLHDLGIVHRDLKPENLL 148
Query: 242 LDPVYHSL------RISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCN 295
Y+SL ISDFG S +++D L+ GTP + APE+
Sbjct: 149 ----YYSLDEDSKIMISDFGLS------------KMEDP-GSVLSTACGTPGYVAPEVL- 190
Query: 296 FAEGSAHASNEQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSS 355
A +D WS+G+ Y +L PF+ E + + I + + D
Sbjct: 191 -------AQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWD 243
Query: 356 NIYGWIHEYVVNRMLSKNTASRPTTSNILR 385
+I ++ + ++ K+ R T L+
Sbjct: 244 DISDSAKDF-IRHLMEKDPEKRFTCEQALQ 272
>Hs14770402 [R] KOG0586 Serine/threonine protein kinase
Length = 926
Score = 75.5 bits (184), Expect = 2e-13
Identities = 84/316 (26%), Positives = 138/316 (43%), Gaps = 69/316 (21%)
Query: 70 VNQYRIGERLGCGQFGTVYKGH--TTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESIS 127
V Y I LG G F V G T VAIK I K +++
Sbjct: 17 VGFYDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKSQLDA------------------ 58
Query: 128 GDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRE 187
+N+ KI E + L+HP++I+L + +++ ++L+ A GE+
Sbjct: 59 -------VNLEKIYREVQIMKMLDHPHIIKLYQVMET--KSMLYLVTEYAKNGEI----- 104
Query: 188 SKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYH 247
FD + G+L+ E A + I + + Y G+ I+HRDLK +N+LLD
Sbjct: 105 --FDYLAN-----HGRLNESE--ARRKFWQILSAVDYCHGRKIVHRDLKAENLLLDN-NM 154
Query: 248 SLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQ 307
+++I+DFG FK G L L G+P + APE+ EG + E
Sbjct: 155 NIKIADFGFGNF------FKSGEL-------LATWCGSPPYAAPEV---FEGQQY---EG 195
Query: 308 PFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIYGWIHEYVVN 367
P ++D+WS+G+ +Y ++ LPF G T + + + S + E+++
Sbjct: 196 P-QLDIWSMGVVLYVLVCGALPFDGPTLPILRQRVLEGRFRIPYFMSEDC-----EHLIR 249
Query: 368 RMLSKNTASRPTTSNI 383
RML + + R T + I
Sbjct: 250 RMLVLDPSKRLTIAQI 265
>At4g24100 [T] KOG0582 Ste20-like serine/threonine protein kinase
Length = 710
Score = 75.5 bits (184), Expect = 2e-13
Identities = 77/261 (29%), Positives = 109/261 (41%), Gaps = 61/261 (23%)
Query: 73 YRIGERLGCGQFGTVYKGH--TTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISGDV 130
Y++ E +G G VY+ T +VVAIK + NS
Sbjct: 33 YKLMEEIGHGASAVVYRAIYLPTNEVVAIKCLDLDRCNS--------------------- 71
Query: 131 LIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESKF 190
N+ IR E S ++HPNVI+ +S +W++ P G
Sbjct: 72 -----NLDDIRRESQTMSLIDHPNVIKSFCSFSVDHS--LWVVMPFMAQGSC-------- 116
Query: 191 DLIEQWKSFYRGQLDSVEEFAVK-VLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYHSL 249
+ K+ Y D EE A+ VL + L YL QG IHRD+K NILLD +
Sbjct: 117 --LHLMKTAYS---DGFEESAICCVLKETLKALDYLHRQGHIHRDVKAGNILLDD-NGEI 170
Query: 250 RISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQPF 309
++ DFG S + F +G Q + N VGTP + APE+ G+ + S
Sbjct: 171 KLGDFGVSACL-----FDNGDRQ----RARNTFVGTPCWMAPEV--LQPGNGYNS----- 214
Query: 310 KIDVWSLGITVYAILYNVLPF 330
K D+WS GIT + + PF
Sbjct: 215 KADIWSFGITALELAHGHAPF 235
>7294217 [D] KOG0588 Serine/threonine protein kinase
Length = 851
Score = 75.5 bits (184), Expect = 2e-13
Identities = 75/265 (28%), Positives = 120/265 (44%), Gaps = 64/265 (24%)
Query: 68 KFVNQYRIGERLGCGQFGTVYKGH--TTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYES 125
+FV YR+ + LG GQ G V G GK VAIK I ++ + S S++MK
Sbjct: 13 QFVGPYRLEKTLGKGQTGLVKLGVHCVIGKKVAIKIINREKL----SESVLMK------- 61
Query: 126 ISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWS 185
+ ++ IM++ ++HP+V+ L + ++ ++LI GEL
Sbjct: 62 VEREIAIMKL--------------IDHPHVLGLSDVYEN--KKYLYLILEHVSGGEL--- 102
Query: 186 RESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPV 245
FD + + +G+L E A K I + L + I HRDLKP+N+LLD
Sbjct: 103 ----FDYLVK-----KGRLTPKE--ARKFFRQIISALDFCHSHSICHRDLKPENLLLDE- 150
Query: 246 YHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASN 305
++++I+DFG + + P+ L G+P + PE+ +
Sbjct: 151 KNNIKIADFGMASLQPA-------------GSMLETSCGSPHYACPEVIRGEKYDGR--- 194
Query: 306 EQPFKIDVWSLGITVYAILYNVLPF 330
K DVWS G+ +YA+L LPF
Sbjct: 195 ----KADVWSCGVILYALLVGALPF 215
>CE21025 [D] KOG0580 Serine/threonine protein kinase
Length = 326
Score = 75.1 bits (183), Expect = 2e-13
Identities = 59/268 (22%), Positives = 122/268 (45%), Gaps = 65/268 (24%)
Query: 70 VNQYRIGERLGCGQFGTVY--KGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESIS 127
++ + +G LG G+FG V+ + T +++A+K ++K +
Sbjct: 41 LDDFDVGRPLGKGKFGNVFISREKKTKRIIALKVLFKTQL-------------------- 80
Query: 128 GDVLIMEMNVS-KIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSR 186
+++ VS +++ E + L HPN++ L ++++I A GEL
Sbjct: 81 -----LQLGVSHQLKREIEIQYHLRHPNILTLYGYFHD--DKRVFVILDYASRGEL---- 129
Query: 187 ESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVY 246
F++++ ++ A + + ++N L Y +G+IHRD+KP+N+LLD
Sbjct: 130 ---FNVLQSQPGHKVNEV-----IAGRFVRQLANALHYCHSKGVIHRDIKPENLLLDSKL 181
Query: 247 HSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNE 306
+L+++DFG S++ + + + GT + APE+ ++
Sbjct: 182 -NLKLADFGWSVVAD--------------HSKRHTLCGTMDYLAPEMV--------SNQP 218
Query: 307 QPFKIDVWSLGITVYAILYNVLPFWGET 334
F +D+W++GI ++ +L PF +T
Sbjct: 219 HDFNVDIWAIGILLFEMLVGYAPFANQT 246
>CE00847 [T] KOG0583 Serine/threonine protein kinase
Length = 622
Score = 75.1 bits (183), Expect = 2e-13
Identities = 74/263 (28%), Positives = 116/263 (43%), Gaps = 63/263 (23%)
Query: 70 VNQYRIGERLGCGQFGTVYKGH--TTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESIS 127
+ + I E +G G FG V +G TG VAIK + + M + + KT +++
Sbjct: 21 IGNFVIKETIGKGAFGAVKRGTHIQTGYDVAIKILNRGRMKG---LGTVNKTRNEIDNLQ 77
Query: 128 GDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRE 187
KL HP++ +L + +P I+L+ L GEL
Sbjct: 78 ---------------------KLTHPHITRLFRVISTP--SDIFLVMELVSGGEL----- 109
Query: 188 SKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYH 247
F I + +G L E + + I +G+ Y I+HRDLKP+N+LLD
Sbjct: 110 --FSYITR-----KGALPIRE--SRRYFQQIISGVSYCHNHMIVHRDLKPENLLLD-ANK 159
Query: 248 SLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQ 307
+++I+DFG S + DG L L+ G+P + APEL + + E
Sbjct: 160 NIKIADFGLSNYM------TDGDL-------LSTACGSPNYAAPELIS---NKLYVGPE- 202
Query: 308 PFKIDVWSLGITVYAILYNVLPF 330
+D+WS G+ +YA+L LPF
Sbjct: 203 ---VDLWSCGVILYAMLCGTLPF 222
>At5g66210 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 523
Score = 75.1 bits (183), Expect = 2e-13
Identities = 82/328 (25%), Positives = 133/328 (40%), Gaps = 72/328 (21%)
Query: 65 HAQKFVNQYRIGERLGCGQFGTVYKG--HTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKR 122
+++ F + Y IG+ LG GQFG Y G VA+K++ K M P ++ + + ++
Sbjct: 54 YSKDFHDHYTIGKLLGHGQFGYTYVAIHRPNGDRVAVKRLDKSKMVLPIAVEDVKREVQI 113
Query: 123 YESISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGEL 182
++SG H NV+Q + D ++++ L GEL
Sbjct: 114 LIALSG-----------------------HENVVQFHNAFED--DDYVYIVMELCEGGEL 148
Query: 183 QWSRESKFDLIEQWKSFYRGQLDS--VEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNI 240
D I K + D+ V +KV G+ G++HRD+KP+N
Sbjct: 149 -------LDRILSKKGNRYSEKDAAVVVRQMLKVAGECHL-------HGLVHRDMKPENF 194
Query: 241 LLDPVY--HSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAE 298
L L+ +DFG S + K G K + IVG+ + APE+
Sbjct: 195 LFKSAQLDSPLKATDFGLSDFI------KPG-------KRFHDIVGSAYYVAPEVLKRRS 241
Query: 299 GSAHASNEQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNS--SN 356
G + DVWS+G+ Y +L PFW TE + + KPD +
Sbjct: 242 GP---------ESDVWSIGVITYILLCGRRPFWDRTEDGIFKEVLRN--KPDFSRKPWAT 290
Query: 357 IYGWIHEYVVNRMLSKNTASRPTTSNIL 384
I ++ V ++L K+ +R T + L
Sbjct: 291 ISDSAKDF-VKKLLVKDPRARLTAAQAL 317
>At3g10540 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 483
Score = 75.1 bits (183), Expect = 2e-13
Identities = 75/300 (25%), Positives = 133/300 (44%), Gaps = 53/300 (17%)
Query: 83 QFGTVYKGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISGDVLIMEMNVSKIRW 142
+ G +Y + KVV K KK + +++ ++ K + E + ++
Sbjct: 43 ELGKIYGVGSYSKVVRAK---KKDNGTVYALKIMDKKF----------ITKENKTAYVKL 89
Query: 143 ECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESKFDLIEQWKSFYRG 202
E V +L HP +++L S +++ GEL FD I + +G
Sbjct: 90 ERIVLDQLEHPGIVKLFFTFQDTQS--LYMALESCEGGEL-------FDQITR-----KG 135
Query: 203 QLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYHSLRISDFGCSLIVPS 262
+L E+ A ++ + L+Y+ G+IHRD+KP+N+LL H ++I+DFG S
Sbjct: 136 RLS--EDEARFYSAEVVDALEYIHNMGLIHRDIKPENLLLTLDGH-IKIADFG------S 186
Query: 263 KLPFKDGRLQDL----FEKELNKIVGTPLFTAPELCNFAEGSAHASNEQPFKIDVWSLGI 318
P +D ++ L + + VGT + PE+ N S+ F D+W+LG
Sbjct: 187 VKPMQDSQITVLPNAASDDKACTFVGTAAYVPPEVLN--------SSPATFGNDLWALGC 238
Query: 319 TVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIYGWIHEYVVNRMLSKNTASRP 378
T+Y +L PF +E+ + I R +K H S +++R+L + + RP
Sbjct: 239 TLYQMLSGTSPFKDASEWLIFQRIIARDIKFPNHFSE-----AARDLIDRLLDTDPSRRP 293
>SPCC18B5.11c [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 460
Score = 74.7 bits (182), Expect = 3e-13
Identities = 82/319 (25%), Positives = 138/319 (42%), Gaps = 58/319 (18%)
Query: 71 NQYRIGERLGCGQFGTVYKGH--TTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISG 128
+ Y I LG G F V +GK AIK I K+ + L+ + KR +
Sbjct: 165 SHYEIIRTLGSGTFAVVKLAVEVNSGKWYAIKIINKRKI-------LLTSSEKR----AT 213
Query: 129 DVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRES 188
++ E+++ K L+HP V+Q E ++ D+++++ G+L
Sbjct: 214 EMFQREIDILK---------SLHHPGVVQCHEIFEN--DDELFIVMEYVEGGDLM----- 257
Query: 189 KFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYHS 248
D + G +D E+ +L + L +L QG+ HRD+KP+NIL+ +H
Sbjct: 258 --DFL-----IANGSID--EQDCKPLLKQLLETLLHLHKQGVTHRDIKPENILITNDFH- 307
Query: 249 LRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQP 308
L+ISDFG + ++ F L GT + APE+ + +
Sbjct: 308 LKISDFGLAKVIHGTGTF------------LETFCGTMGYLAPEVLKSKNVNLDGGYDD- 354
Query: 309 FKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICH--RQLKPDVHNSSNIYGWIHEYVV 366
K+D+WSLG +Y +L +PF ++ LI ++P + N + G ++
Sbjct: 355 -KVDIWSLGCVLYVMLTASIPFASSSQAKCIELISKGAYPIEPLLENEISEEG---IDLI 410
Query: 367 NRMLSKNTASRPTTSNILR 385
NRML N R + S L+
Sbjct: 411 NRMLEINPEKRISESEALQ 429
>CE24516 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 856
Score = 74.7 bits (182), Expect = 3e-13
Identities = 72/275 (26%), Positives = 123/275 (44%), Gaps = 72/275 (26%)
Query: 72 QYRIGERLGCGQFGTVYKGHTTGKV---VAIKQIYKKPMNSPFSMSLIMKTMKRYESISG 128
+Y + LG G F VY+G + VAIK I KK ++ S +L+ K +K + +S
Sbjct: 8 EYSKRDLLGHGAFAIVYRGRYVDRTDVPVAIKAIAKKNISK--SKNLLTKEIKILKELSS 65
Query: 129 DVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRES 188
L H N++ LL+C ++P ++L+ G+L +
Sbjct: 66 ---------------------LKHENLVGLLKCTETP--THVYLVMEFCNGGDLADYLQQ 102
Query: 189 KFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILL------ 242
K L E D+++ F V+ I++ L+ + +GI+HRDLKPQNILL
Sbjct: 103 KTTLNE----------DTIQHFVVQ----IAHALEAINKKGIVHRDLKPQNILLCNNSRT 148
Query: 243 -DPVYHS--LRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEG 299
+P + ++++DFG + + DG + + G+P++ APE+
Sbjct: 149 QNPHFTDIVIKLADFGFARFL------NDGVM-------AATLCGSPMYMAPEVI----- 190
Query: 300 SAHASNEQPFKIDVWSLGITVYAILYNVLPFWGET 334
S + K D+WS+G ++ L PF +T
Sbjct: 191 ---MSMQYDAKADLWSIGTILFQCLTGKAPFVAQT 222
>CE16081 [T] KOG0583 Serine/threonine protein kinase
Length = 334
Score = 74.7 bits (182), Expect = 3e-13
Identities = 70/272 (25%), Positives = 126/272 (45%), Gaps = 64/272 (23%)
Query: 73 YRIGERLGCGQFGTVYKG--HTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISGDV 130
YR+G+ LG G F V G T + VA+K + K M++ K + +S ++
Sbjct: 49 YRLGKELGAGNFSKVKLGVHQLTKEKVAVKIMDKAKMDA-----------KAQKLLSREI 97
Query: 131 LIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESKF 190
ME ++NHPN+++L E +++ ++ L+ A GEL +
Sbjct: 98 QAME--------------EMNHPNIVKLFEVVET--LTRVHLVIEYASGGEL-------Y 134
Query: 191 DLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYHSLR 250
+ + RG+L E A + I + + ++ + I+HRD+K +N++ ++++
Sbjct: 135 TYVHE-----RGKL--TEGDAKPLFAQIVSAVSHMHSRNIVHRDIKAENVMFSSP-NTVK 186
Query: 251 ISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQPFK 310
+ DFG S +V E+ L G+P + APEL + +++A
Sbjct: 187 LVDFGFSCLVDR-------------EQMLRTFCGSPPYAAPELF---QDTSYAGE----L 226
Query: 311 IDVWSLGITVYAILYNVLPFWGETEFDTYNLI 342
+DVW+LG+ ++ +L V PF ET D LI
Sbjct: 227 VDVWALGVLLFFMLIGVTPFKAETVPDMKVLI 258
>YPL153c [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 821
Score = 74.3 bits (181), Expect = 4e-13
Identities = 74/278 (26%), Positives = 110/278 (38%), Gaps = 67/278 (24%)
Query: 75 IGERLGCGQFGTVYKG--HTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISGDVLI 132
I E +G G F TV K TTGK A+K I K+ +
Sbjct: 200 IDEVVGQGAFATVKKAIERTTGKTFAVKIISKRKVIG----------------------- 236
Query: 133 MEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESKFDL 192
N+ + E V KLNHP +++L + ++ +++ G+L
Sbjct: 237 ---NMDGVTRELEVLQKLNHPRIVRLKGFYED--TESYYMVMEFVSGGDLM--------- 282
Query: 193 IEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILL---DPVYHSL 249
F E+ ++ I ++Y+ GI HRDLKP NIL+ DPV +
Sbjct: 283 -----DFVAAHGAVGEDAGREISRQILTAIKYIHSMGISHRDLKPDNILIEQDDPVL--V 335
Query: 250 RISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHAS----- 304
+I+DFG + + + G F GT + APE+ + S
Sbjct: 336 KITDFGLAKVQGN------GSFMKTF-------CGTLAYVAPEVIRGKDTSVSPDEYEER 382
Query: 305 NEQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLI 342
NE +D+WS+G VY IL LPF G T+ Y I
Sbjct: 383 NEYSSLVDMWSMGCLVYVILTGHLPFSGSTQDQLYKQI 420
>YKL101w [D] KOG0588 Serine/threonine protein kinase
Length = 1518
Score = 74.3 bits (181), Expect = 4e-13
Identities = 75/275 (27%), Positives = 121/275 (43%), Gaps = 51/275 (18%)
Query: 70 VNQYRIGERLGCGQFGTVY--KGHTTGKVVAIKQIYKKP----------MNSPFSMSLIM 117
V +++G+ LG G G V K TG++ AIK + KK + + +S S++
Sbjct: 78 VGPWKLGKTLGKGSSGRVRLAKNMETGQLAAIKIVPKKKAFVHCSNNGTVPNSYSSSMVT 137
Query: 118 KTMKRYESISGDVLI-MEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPL 176
+ S + + N I E + ++H NV+ L E ++ +++L+
Sbjct: 138 SNVSSPSIASREHSNHSQTNPYGIEREIVIMKLISHTNVMALFEVWEN--KSELYLVLEY 195
Query: 177 AVLGELQWSRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLK 236
GEL FD + +G+L E A+ I G+ Y I HRDLK
Sbjct: 196 VDGGEL-------FDYLVS-----KGKLPERE--AIHYFKQIVEGVSYCHSFNICHRDLK 241
Query: 237 PQNILLDPVYHSLRISDFG-CSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCN 295
P+N+LLD ++I+DFG +L +P+KL L G+P + +PE+
Sbjct: 242 PENLLLDKKNRRIKIADFGMAALELPNKL--------------LKTSCGSPHYASPEI-- 285
Query: 296 FAEGSAHASNEQPFKIDVWSLGITVYAILYNVLPF 330
G + DVWS GI ++A+L LPF
Sbjct: 286 -VMGRPYHGGPS----DVWSCGIVLFALLTGHLPF 315
>7299793 [T] KOG0583 Serine/threonine protein kinase
Length = 540
Score = 74.3 bits (181), Expect = 4e-13
Identities = 74/279 (26%), Positives = 125/279 (44%), Gaps = 65/279 (23%)
Query: 62 QEEHAQKFVNQYRIGERLGCGQFGTVYKGHTTGKVVAIKQIYKKPMNSPFSMSLIMK--T 119
Q++ + K V +Y +G+ LG G +G V K+ MNS L +K T
Sbjct: 134 QKKKSIKMVGKYIMGDVLGEGSYGKV----------------KEAMNSENLCRLAVKILT 177
Query: 120 MKRYESISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVL 179
++ I E NV++ E + +L H +V++L++ L + +++L+ V
Sbjct: 178 KRKLRRIPNG----EQNVTR---EIALLKQLKHRHVVELVDVLYNEEKQKMYLVMEYCVG 230
Query: 180 G---ELQWSRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLK 236
G + + + + L + F + + +GL+YL +IH+D+K
Sbjct: 231 GLQEMIDYQPDKRMPLFQAHGYFKQ----------------LVDGLEYLHSCRVIHKDIK 274
Query: 237 PQNILLDPVYHSLRISDFGCSLIVPSKLPFKDGRLQDLF--EKELNKIVGTPLFTAPELC 294
P N+LL + +L+ISDFG V +L DLF + G+P F PE+
Sbjct: 275 PGNLLLS-LDQTLKISDFG----VAEQL--------DLFAPDDTCTTGQGSPAFQPPEIA 321
Query: 295 NFAEGSAHASNEQPFKIDVWSLGITVYAILYNVLPFWGE 333
N E A FK+D+WS G+T+Y + PF G+
Sbjct: 322 NGHETFA------GFKVDIWSSGVTLYNLATGQYPFEGD 354
>7299536 [D] KOG0580 Serine/threonine protein kinase
Length = 411
Score = 74.3 bits (181), Expect = 4e-13
Identities = 77/294 (26%), Positives = 120/294 (40%), Gaps = 77/294 (26%)
Query: 70 VNQYRIGERLGCGQFGTVYKGHTTGK--VVAIKQIYKKPMNSPFSMSLIMKTMKRYESIS 127
+N + IG LG G+FG VY VVA+K ++K+ +
Sbjct: 151 LNNFDIGRLLGRGKFGNVYLAREKESQFVVALKVLFKRQIG------------------- 191
Query: 128 GDVLIMEMNVS-KIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGEL---- 182
E NV ++R E + S L HP++++L +I+LI A G L
Sbjct: 192 ------ESNVEHQVRREIEIQSHLRHPHILRLYAYFHDDV--RIYLILEYAPQGTLFNAL 243
Query: 183 QWSRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILL 242
Q +FD E + + + + L YL + IIHRD+KP+N+LL
Sbjct: 244 QAQPMKRFD----------------ERQSATYIQALCSALLYLHERDIIHRDIKPENLLL 287
Query: 243 DPVYHS--LRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGS 300
H L+I+DFG S+ P+ + + GT + PE+ +G
Sbjct: 288 G---HKGVLKIADFGWSVHEPNSMRM--------------TLCGTVDYLPPEM---VQGK 327
Query: 301 AHASNEQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNS 354
H N +D+WSLG+ + +L PF+ + +TY I K H S
Sbjct: 328 PHTKN-----VDLWSLGVLCFELLVGHAPFYSKNYDETYKKILKVDYKLPEHIS 376
>SPAC9G1.02 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and related
serine/threonine protein kinases
Length = 1401
Score = 73.9 bits (180), Expect = 5e-13
Identities = 72/267 (26%), Positives = 117/267 (42%), Gaps = 53/267 (19%)
Query: 72 QYRIGERLGCGQFGTVYKGHT--TGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISGD 129
+++ G + G FG VY G TG ++A+K+I + D
Sbjct: 1036 RWQQGHFVRSGMFGDVYTGVNMETGDLLAVKEIKLQ-----------------------D 1072
Query: 130 VLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESK 189
V +I E V +LNHPNV+ + +++++ G L
Sbjct: 1073 SRTFRSTVDQIHNEMTVLERLNHPNVVTYYGV--EVHREKVYIFMEFCQGGSLA------ 1124
Query: 190 FDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYHSL 249
DL+ G+++ V V+ + GL Y+ Q I+HRD+KP NILLD +
Sbjct: 1125 -DLLAH------GRIEDENVLKVYVV-QLLEGLAYIHSQHILHRDIKPANILLDH-RGMI 1175
Query: 250 RISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPE-LCNFAEGSAHASNEQP 308
+ SDFG +L V S + R +D+ + EL + GTP++ APE + +G A
Sbjct: 1176 KYSDFGSALYV-SPPTDPEVRYEDI-QPELQHLAGTPMYMAPEIILGTKKGDFGA----- 1228
Query: 309 FKIDVWSLGITVYAILYNVLPFWGETE 335
+D+WSLG + ++ P W E +
Sbjct: 1229 --MDIWSLGCVILEMMTGSTP-WSEMD 1252
>Hs18552621 [R] KOG0597 Serine-threonine protein kinase FUSED
Length = 1315
Score = 73.9 bits (180), Expect = 5e-13
Identities = 76/279 (27%), Positives = 122/279 (43%), Gaps = 73/279 (26%)
Query: 70 VNQYRIGERLGCGQFGTVYKGHT--TGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESIS 127
+ +Y + E +G G FG VYKG + +VVA+K I K + ++ K ++
Sbjct: 1 MEKYHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPK-----------LGRSEKELRNLQ 49
Query: 128 GDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRE 187
++ IM L HPN++ +L DS +D+ ++ GEL
Sbjct: 50 REIEIMR--------------GLRHPNIVHML---DSFETDKEVVVVTDYAEGEL----- 87
Query: 188 SKFDLIEQWKSFYRGQL--DSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPV 245
F ++E G+L D V+ A +++ + L YL I+HRD+KPQNILL
Sbjct: 88 --FQILED-----DGKLPEDQVQAIAAQLV----SALYYLHSHRILHRDMKPQNILL-AK 135
Query: 246 YHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASN 305
+++ DFG + R L I GTPL+ +PEL
Sbjct: 136 GGGIKLCDFGFA------------RAMSTNTMVLTSIKGTPLYMSPELV----------E 173
Query: 306 EQPF--KIDVWSLGITVYAILYNVLPFWGETEFDTYNLI 342
E+P+ D+WS+G +Y + PF+ + F +LI
Sbjct: 174 ERPYDHTADLWSVGCILYELAVGTPPFYATSIFQLVSLI 212
>Hs14196445 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 476
Score = 73.9 bits (180), Expect = 5e-13
Identities = 74/270 (27%), Positives = 113/270 (41%), Gaps = 69/270 (25%)
Query: 77 ERLGCGQFGTVY--KGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISGDVLIME 134
E LG G F V+ K TGK+ A+K I K P
Sbjct: 27 EVLGSGAFSEVFLVKQRLTGKLFALKCIKKSP---------------------------A 59
Query: 135 MNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESKFDLIE 194
S + E V K+ H N++ L + +S + +L+ L GEL FD I
Sbjct: 60 FRDSSLENEIAVLKKIKHENIVTLEDIYES--TTHYYLVMQLVSGGEL-------FDRIL 110
Query: 195 QWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNIL-LDPVYHS-LRIS 252
+ + Y E+ A V+ + + ++YL GI+HRDLKP+N+L L P +S + I+
Sbjct: 111 E-RGVY------TEKDASLVIQQVLSAVKYLHENGIVHRDLKPENLLYLTPEENSKIMIT 163
Query: 253 DFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQPFKID 312
DFG S + + + ++ GTP + APE+ A +D
Sbjct: 164 DFGLSKMEQNGI--------------MSTACGTPGYVAPEVL--------AQKPYSKAVD 201
Query: 313 VWSLGITVYAILYNVLPFWGETEFDTYNLI 342
WS+G+ Y +L PF+ ETE + I
Sbjct: 202 CWSIGVITYILLCGYPPFYEETESKLFEKI 231
>CE27573 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 1420
Score = 73.9 bits (180), Expect = 5e-13
Identities = 51/168 (30%), Positives = 79/168 (46%), Gaps = 15/168 (8%)
Query: 222 LQYLQGQGIIHRDLKPQNILLDPVYHSLRISDFGCSL-IVPSKLPFKDGRLQDLFEKELN 280
+QYL IIHRD+KP NI LD L++ DFGCS +V S + E
Sbjct: 1230 VQYLHSHKIIHRDIKPANIFLDKCT-VLKLGDFGCSSRLVESSTVYG----------EFQ 1278
Query: 281 KIVGTPLFTAPELCNFAEGSAHASNEQPF--KIDVWSLGITVYAILYNVLPFWGETEFDT 338
GTP F APE+ ++ E + + +D+W+LG TV ++ +PF G+T
Sbjct: 1279 TTAGTPQFMAPEIYSYGEKDETTGSYSGYGRSVDIWALGATVVNMMTGKVPFEGQTRHQI 1338
Query: 339 YNLICHRQLKPDVHNSSNIYGWIHEYVVNRMLSKNTASRPTTSNILRT 386
+C R+ KP + ++ + + N RPT + +L+T
Sbjct: 1339 AFALCFRKQKPTYPDIADKRPDVKRFFDN-CFEFLPNDRPTAAELLQT 1385
>CE07737 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 1418
Score = 73.9 bits (180), Expect = 5e-13
Identities = 51/168 (30%), Positives = 79/168 (46%), Gaps = 15/168 (8%)
Query: 222 LQYLQGQGIIHRDLKPQNILLDPVYHSLRISDFGCSL-IVPSKLPFKDGRLQDLFEKELN 280
+QYL IIHRD+KP NI LD L++ DFGCS +V S + E
Sbjct: 1230 VQYLHSHKIIHRDIKPANIFLDKCT-VLKLGDFGCSSRLVESSTVYG----------EFQ 1278
Query: 281 KIVGTPLFTAPELCNFAEGSAHASNEQPF--KIDVWSLGITVYAILYNVLPFWGETEFDT 338
GTP F APE+ ++ E + + +D+W+LG TV ++ +PF G+T
Sbjct: 1279 TTAGTPQFMAPEIYSYGEKDETTGSYSGYGRSVDIWALGATVVNMMTGKVPFEGQTRHQI 1338
Query: 339 YNLICHRQLKPDVHNSSNIYGWIHEYVVNRMLSKNTASRPTTSNILRT 386
+C R+ KP + ++ + + N RPT + +L+T
Sbjct: 1339 AFALCFRKQKPTYPDIADKRPDVKRFFDN-CFEFLPNDRPTAAELLQT 1385
>At4g10730 [T] KOG0582 Ste20-like serine/threonine protein kinase
Length = 693
Score = 73.9 bits (180), Expect = 5e-13
Identities = 74/261 (28%), Positives = 107/261 (40%), Gaps = 61/261 (23%)
Query: 73 YRIGERLGCGQFGTVYKGH--TTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISGDV 130
Y++ E +G G V++ T +VVAIK + NS
Sbjct: 27 YKLMEEVGYGASAVVHRAIYLPTNEVVAIKSLDLDRCNS--------------------- 65
Query: 131 LIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESKF 190
N+ IR E + ++HPNVI+ +W++ P G
Sbjct: 66 -----NLDDIRREAQTMTLIDHPNVIKSF--CSFAVDHHLWVVMPFMAQGSC-------- 110
Query: 191 DLIEQWKSFYRGQLDSVEEFAV-KVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYHSL 249
+ K+ Y D EE A+ +L + L YL QG IHRD+K NILLD +
Sbjct: 111 --LHLMKAAYP---DGFEEAAICSMLKETLKALDYLHRQGHIHRDVKAGNILLDDT-GEI 164
Query: 250 RISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQPF 309
++ DFG S + F +G Q + N VGTP + APE+ GS + S
Sbjct: 165 KLGDFGVSACL-----FDNGDRQ----RARNTFVGTPCWMAPEV--LQPGSGYNS----- 208
Query: 310 KIDVWSLGITVYAILYNVLPF 330
K D+WS GIT + + PF
Sbjct: 209 KADIWSFGITALELAHGHAPF 229
>SPCC74.03c [T] KOG0583 Serine/threonine protein kinase
Length = 576
Score = 73.6 bits (179), Expect = 6e-13
Identities = 80/270 (29%), Positives = 120/270 (43%), Gaps = 64/270 (23%)
Query: 63 EEHAQKFVNQYRIGERLGCGQFGTVYKG--HTTGKVVAIKQIYKKPMNSPFSMSLIMKTM 120
E +++ + Y I E LG G FG V + T + VA+K I S L+ K+
Sbjct: 24 EAISKRHIGPYIIRETLGEGSFGKVKLATHYKTQQKVALKFI---------SRQLLKKSD 74
Query: 121 KRYESISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLG 180
M M V + E L HP++I+L + + +P +D + +I+ G
Sbjct: 75 ------------MHMRVER---EISYLKLLRHPHIIKLYDVITTP-TDIVMVIEYAG--G 116
Query: 181 ELQWSRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNI 240
EL FD I + K E+ + I ++Y I+HRDLKP+N+
Sbjct: 117 EL-------FDYIVEKKRM-------TEDEGRRFFQQIICAIEYCHRHKIVHRDLKPENL 162
Query: 241 LLDPVYHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGS 300
LLD +++I+DFG S I+ DG L G+P + APE+ N G
Sbjct: 163 LLDDNL-NVKIADFGLSNIM------TDGNF-------LKTSCGSPNYAAPEVIN---GK 205
Query: 301 AHASNEQPFKIDVWSLGITVYAILYNVLPF 330
+A E +DVWS GI +Y +L LPF
Sbjct: 206 LYAGPE----VDVWSCGIVLYVMLVGRLPF 231
>SPCC162.10 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 338
Score = 73.6 bits (179), Expect = 6e-13
Identities = 77/273 (28%), Positives = 118/273 (43%), Gaps = 80/273 (29%)
Query: 70 VNQYRIGERLGCGQFGTVY--KGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESIS 127
V+Q++I +G G + TV+ K T + A+K I KK +
Sbjct: 27 VSQFKIRNVIGKGSWSTVFVVKHRQTKQRFALKCINKKKHD------------------- 67
Query: 128 GDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQ--IWLIQPLAVLGELQW- 184
E + K+R E + LNHP LL S + D+ I+L+ L + G+L++
Sbjct: 68 ------EHKIKKLRNEVLLLQSLNHP----LLCKFYSEFEDETKIYLVTDLMLGGDLRYH 117
Query: 185 --SRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILL 242
R+ +I W + ++ + L Y+ +G++HRD+KP NILL
Sbjct: 118 ISQRKFNESVIRIW------------------MVELVSALIYIHSKGVLHRDVKPDNILL 159
Query: 243 DPVYHSLRISDFGCSLIV-----PSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFA 297
D H +++DF + V PSK GR VGTP++ APE
Sbjct: 160 DEKGH-CKLADFNVAAKVHTSSSPSKSNMTVGR------------VGTPVYMAPETL--- 203
Query: 298 EGSAHASNEQPFKIDVWSLGITVYAILYNVLPF 330
HA + + + D WSLGIT Y L+ V PF
Sbjct: 204 ---IHAVSYK--ESDWWSLGITFYECLFQVRPF 231
>SPBC1861.09 [R] KOG0610 Putative serine/threonine protein kinase
Length = 526
Score = 73.6 bits (179), Expect = 6e-13
Identities = 77/302 (25%), Positives = 126/302 (41%), Gaps = 57/302 (18%)
Query: 94 GKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISGDVLIMEMNVSKIRWECFVTSKLNHP 153
GKV ++Q K + F+M ++ K +I V+++ E + +K HP
Sbjct: 167 GKVYLVRQ---KSNHRLFAMKILNKRE----------MIKRHKVNRVLAEQEILTKSKHP 213
Query: 154 NVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRES--KFDLIEQWKSFYRGQLDSVEEFA 211
++ L S D ++L GE + S K L E+ FY +
Sbjct: 214 FIVTLYHSFQS--RDYLYLCMEYCAGGEFFRALHSLPKHILPEKDACFYAAE-------- 263
Query: 212 VKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYHSLRISDFGCS----------LIVP 261
++ L+YL G I+RDLKP+NILL H + +SDF S +++P
Sbjct: 264 ------VTAALEYLHLMGFIYRDLKPENILLHQSGH-IMLSDFDLSKPISIVTHPTVVLP 316
Query: 262 SKLPFKDGR----LQDLFEK-ELNKIVGTPLFTAPELCNFAEGSAHASNEQPFKIDVWSL 316
F + F N VGT + APE+ S +D W+L
Sbjct: 317 KHSTFSQEKPALDTNSYFSNFRTNSFVGTEEYIAPEVIR--------SCGHTVAVDWWTL 368
Query: 317 GITVYAILYNVLPFWGETEFDTYNLICHRQLK-PDVHNSSNIYGWIHEYVVNRMLSKNTA 375
GI +Y ILY PF G+ T++ I + + P+ H + N+ + ++ R+L K+ +
Sbjct: 369 GIFIYEILYGTTPFKGKNRHATFSNILYSDVSFPEYHGAPNVSSTC-KSLIRRLLVKDES 427
Query: 376 SR 377
R
Sbjct: 428 KR 429
>SPACUNK12.02c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 335
Score = 73.6 bits (179), Expect = 6e-13
Identities = 73/264 (27%), Positives = 120/264 (44%), Gaps = 65/264 (24%)
Query: 72 QYRIGERLGCGQFGTVYKGH--TTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISGD 129
+YR+G LG G + TV + T K+ A K + KK M K+ + + +
Sbjct: 30 KYRVGRVLGGGTYATVREAVHIETNKMYAAKIMNKKMME------------KKQDFVKNE 77
Query: 130 VLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESK 189
+ I++ ++ +E HPN++ L++ ++ + ++LI LA GEL
Sbjct: 78 IAILK----RVSYE--------HPNILHLVDFFETV--NNLYLITELATGGEL------- 116
Query: 190 FDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILL---DPVY 246
FD I SFY E A ++ ++ ++YL GI+HRDLKP+N+L DP
Sbjct: 117 FDRICAKGSFY-------EADAAALMRTTTSAVKYLHDNGIVHRDLKPENLLYRSKDP-N 168
Query: 247 HSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNE 306
L I+DFG S ++D + L GTP + APE+
Sbjct: 169 SDLLIADFGLSHF------YEDSQYYMLM-----TACGTPEYMAPEVFR------RTGYG 211
Query: 307 QPFKIDVWSLGITVYAILYNVLPF 330
+P +D+W++G+ Y +L PF
Sbjct: 212 KP--VDMWAIGVITYFLLSGYTPF 233
>Hs4826878 [T] KOG0582 Ste20-like serine/threonine protein kinase
Length = 527
Score = 73.6 bits (179), Expect = 6e-13
Identities = 65/258 (25%), Positives = 111/258 (42%), Gaps = 30/258 (11%)
Query: 134 EMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESKFDLI 193
+ ++ ++ E S+ +HPN++ D++WL+ L G S D+I
Sbjct: 54 QTSMDELLKEIQAMSQCHHPNIVSYYTSF--VVKDELWLVMKLLSGG-------SVLDII 104
Query: 194 EQWKSFYRGQLDSVEEFAVK-VLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYHSLRIS 252
+ + + ++E + +L ++ GL+YL G IHRD+K NILL S++I+
Sbjct: 105 KHIVAKGEHKSGVLDESTIATILREVLEGLEYLHKNGQIHRDVKAGNILLGE-DGSVQIA 163
Query: 253 DFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQPFKID 312
DFG S + + +++ F VGTP + APE+ G FK D
Sbjct: 164 DFGVSAFLATGGDITRNKVRKTF-------VGTPCWMAPEVMEQVRG-------YDFKAD 209
Query: 313 VWSLGITVYAILYNVLPFWGETEFDTYNLICHR---QLKPDVHNSSNI--YGWIHEYVVN 367
+WS GIT + P+ L L+ V + + YG +++
Sbjct: 210 IWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPSLETGVQDKEMLKKYGKSFRKMIS 269
Query: 368 RMLSKNTASRPTTSNILR 385
L K+ RPT + +LR
Sbjct: 270 LCLQKDPEKRPTAAELLR 287
>Hs4507273 [D] KOG0580 Serine/threonine protein kinase
Length = 275
Score = 73.6 bits (179), Expect = 6e-13
Identities = 72/286 (25%), Positives = 120/286 (41%), Gaps = 73/286 (25%)
Query: 70 VNQYRIGERLGCGQFGTVYKGHTTGK--VVAIKQIYKKPMNSPFSMSLIMKTMKRYESIS 127
V+ + IG LG G+FG VY +VA+K ++K +
Sbjct: 6 VDDFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEK------------------ 47
Query: 128 GDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGEL--QWS 185
E ++R E + + L HPN+++L + +++LI A GEL +
Sbjct: 48 ------EGLEHQLRREIEIQAHLQHPNILRLYNYFHD--ARRVYLILEYAPRGELYKELQ 99
Query: 186 RESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPV 245
+ K D E+ ++ ++++ L Y + +IHRD+KP+N+LL
Sbjct: 100 KSEKLD----------------EQRTATIIEEVADALTYCHDKKVIHRDIKPENLLLG-F 142
Query: 246 YHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASN 305
++I+DFG S+ P LP E + GT + PE+ EG +
Sbjct: 143 RGEVKIADFGWSVHTP--LP------------ERKTMCGTLDYLPPEM---IEGRTYDE- 184
Query: 306 EQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDV 351
K+D+W +G+ Y +L PF + +TY R LK DV
Sbjct: 185 ----KVDLWCIGVLCYELLVGYPPFESASHSETY----RRILKVDV 222
>Hs20479818 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 514
Score = 73.6 bits (179), Expect = 6e-13
Identities = 76/323 (23%), Positives = 141/323 (43%), Gaps = 73/323 (22%)
Query: 73 YRIGERLGCGQFGTVYKGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISGDVLI 132
Y G LG G FG V + T K K KK +N + S +K ++R
Sbjct: 116 YTFGRILGKGSFGIVIEA--TDKETETKWAIKK-VNKEKAGSSAVKLLER---------- 162
Query: 133 MEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESKFDL 192
E+N+ K + H ++I L + ++P +++L+ L GEL+ + K
Sbjct: 163 -EVNILK---------SVKHEHIIHLEQVFETP--KKMYLVMELCEDGELKEILDRKGHF 210
Query: 193 IEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILL--------DP 244
E + ++ +++ + YL I+HRDLK +NI++ +
Sbjct: 211 SENETRW--------------IIQSLASAIAYLHNNDIVHRDLKLENIMVKSSLIDDNNE 256
Query: 245 VYHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHAS 304
+ +++++DFG ++ + Q E L GTP++ APE+ SAH
Sbjct: 257 INLNIKVTDFGLAV-----------KKQSRSEAMLQATCGTPIYMAPEVI-----SAHDY 300
Query: 305 NEQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIYGWIHE- 363
++Q D+WS+G+ +Y +L PF +E + LI K ++H + ++ I +
Sbjct: 301 SQQ---CDIWSIGVVMYMLLRGEPPFLASSEEKLFELI----RKGELHFENAVWNSISDC 353
Query: 364 --YVVNRMLSKNTASRPTTSNIL 384
V+ +++ + A R T +L
Sbjct: 354 AKSVLKQLMKVDPAHRITAKELL 376
>At2g34180 [T] KOG0583 Serine/threonine protein kinase
Length = 502
Score = 73.6 bits (179), Expect = 6e-13
Identities = 77/318 (24%), Positives = 134/318 (41%), Gaps = 66/318 (20%)
Query: 70 VNQYRIGERLGCGQFGTVYKGHT--TGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESIS 127
+++Y IG+ LG G F VY +G+ VAIK I K+
Sbjct: 54 MDKYEIGKLLGHGSFAKVYLARNIHSGEDVAIKVIDKEK--------------------- 92
Query: 128 GDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRE 187
++ I+ E + ++ HP ++ LLE + + +I+++ GEL
Sbjct: 93 ---IVKSGLAGHIKREISILRRVRHPYIVHLLEVMAT--KTKIYIVMEYVRGGEL----- 142
Query: 188 SKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYH 247
+ + RG+L E A + + + + + +G+ HRDLK +N+LLD
Sbjct: 143 --------YNTVARGRLR--EGTARRYFQQLISSVAFCHSRGVYHRDLKLENLLLDD-KG 191
Query: 248 SLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQ 307
++++SDFG S++ S+ ++G Q GTP + APE+ +
Sbjct: 192 NVKVSDFGLSVV--SEQLKQEGICQ--------TFCGTPAYLAPEVLT-------RKGYE 234
Query: 308 PFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIYGWIHEYVVN 367
K D+WS G+ ++ ++ LPF + Y I Q K S + +V
Sbjct: 235 GAKADIWSCGVILFVLMAGYLPFDDKNILVMYTKIYKGQFKCPKWFSPEL-----ARLVT 289
Query: 368 RMLSKNTASRPTTSNILR 385
RML N +R T I++
Sbjct: 290 RMLDTNPDTRITIPEIMK 307
>SPCC70.05c [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 781
Score = 73.2 bits (178), Expect = 8e-13
Identities = 68/227 (29%), Positives = 102/227 (43%), Gaps = 44/227 (19%)
Query: 137 VSKIRWECFVTSKLNHPNVIQLLE-CLDSP----YSDQIWLIQPLAVLGELQWSRESKFD 191
++K+ E V ++ HPNV++ + C+DS YSD + G+L E + D
Sbjct: 495 IAKLASEWLVQCRMEHPNVVKSYDLCIDSHIFPLYSDTWCAVMDFCPRGDLLSLIEDRHD 554
Query: 192 LIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYHSLRI 251
+ + K F E +K I GL Y+ QGI HRD+KP+NIL+ Y LRI
Sbjct: 555 RLGK-KDF---------ECMIK---QILRGLNYIHSQGIAHRDIKPENILISE-YGVLRI 600
Query: 252 SDFG-CSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQPFK 310
+DFG C ++ G E + I G+ + APE+ GS +A F
Sbjct: 601 TDFGACDVLC------NPGDDITAVESKSMGIFGSDPYMAPEI--LTPGSYNA-----FF 647
Query: 311 IDVWSLGITVYAILYNVLPFWGETEFD-----------TYNLICHRQ 346
D+WS I ++ + + PF ++ D YNLIC Q
Sbjct: 648 ADMWSTAIVLHCLYFRTYPFRKASQNDQLYAKYCKAWREYNLICDVQ 694
>SPAC9G1.09 [T] KOG0201 Serine/threonine protein kinase
Length = 471
Score = 73.2 bits (178), Expect = 8e-13
Identities = 70/261 (26%), Positives = 109/261 (40%), Gaps = 65/261 (24%)
Query: 71 NQYRIGERLGCGQFGTVYKG--HTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISG 128
N Y + +LG G FG V+K + +G ++AIKQI
Sbjct: 7 NSYTLLRKLGSGSFGVVWKARENVSGDIIAIKQI-------------------------- 40
Query: 129 DVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRES 188
D+ +++ I E F+ S N NVIQ C Y+ +W++ G +
Sbjct: 41 DLETGIDDITDIEQEVFMLSNCNSSNVIQYYGCFVDGYT--LWILMEHMDGGSVS----- 93
Query: 189 KFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYHS 248
L++ G+L+ E+ +L ++ GL YL GQ IHRD+K NILL +
Sbjct: 94 --GLLKM------GRLN--EQVISIILREVLYGLNYLHGQNKIHRDIKAANILLSSSTGN 143
Query: 249 LRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQP 308
++++DFG V ++L R + VGTP + APE+
Sbjct: 144 VKLADFG----VAAQLSNAASR--------RHTFVGTPFWMAPEVIQ--------QTSYG 183
Query: 309 FKIDVWSLGITVYAILYNVLP 329
D+WSLGIT + + P
Sbjct: 184 LAADIWSLGITAIEMANGIPP 204
>Hs5803125 [T] KOG0583 Serine/threonine protein kinase
Length = 334
Score = 73.2 bits (178), Expect = 8e-13
Identities = 84/320 (26%), Positives = 135/320 (41%), Gaps = 66/320 (20%)
Query: 67 QKFVNQYRIGERLGCGQFGTVYKGH--TTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYE 124
+ F +YR+G LG G FGTV+ GH T VAIK I P N S +
Sbjct: 26 EAFEAEYRLGPLLGKGGFGTVFAGHRLTDRLQVAIKVI---PRNRVLGWSPL-------- 74
Query: 125 SISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQW 184
D + + V+ + W+ V + HP VI+LL+ ++ + L +PL
Sbjct: 75 ---SDSVTCPLEVALL-WK--VGAGGGHPGVIRLLDWFETQEGFMLVLERPLPA------ 122
Query: 185 SRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDP 244
+ FD I + +G L E + G + +Q+ +G++HRD+K +NIL+D
Sbjct: 123 --QDLFDYITE-----KGPLG--EGPSRCFFGQVVAAIQHCHSRGVVHRDIKDENILIDL 173
Query: 245 VYHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHAS 304
++ DFG ++ + P+ D GT +++ PE S H
Sbjct: 174 RRGCAKLIDFGSGALLHDE-PYTD-------------FDGTRVYSPPEWI-----SRHQY 214
Query: 305 NEQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIYGWIHEY 364
+ P VWSLGI +Y ++ +PF + E L + PD
Sbjct: 215 HALP--ATVWSLGILLYDMVCGDIPFERDQEILEAELHFPAHVSPDCC-----------A 261
Query: 365 VVNRMLSKNTASRPTTSNIL 384
++ R L+ +SRP+ IL
Sbjct: 262 LIRRCLAPKPSSRPSLEEIL 281
>Hs13649368 [T] KOG0583 Serine/threonine protein kinase
Length = 311
Score = 73.2 bits (178), Expect = 8e-13
Identities = 84/320 (26%), Positives = 135/320 (41%), Gaps = 66/320 (20%)
Query: 67 QKFVNQYRIGERLGCGQFGTVYKGH--TTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYE 124
+ F +YR+G LG G FGTV+ GH T VAIK I P N S +
Sbjct: 26 EAFEAEYRLGPLLGKGGFGTVFAGHRLTDRLQVAIKVI---PRNRVLGWSPL-------- 74
Query: 125 SISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQW 184
D + + V+ + W+ V + HP VI+LL+ ++ + L +PL
Sbjct: 75 ---SDSVTCPLEVALL-WK--VGAGGGHPGVIRLLDWFETQEGFMLVLERPLPA------ 122
Query: 185 SRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDP 244
+ FD I + +G L E + G + +Q+ +G++HRD+K +NIL+D
Sbjct: 123 --QDLFDYITE-----KGPLG--EGPSRCFFGQVVAAIQHCHSRGVVHRDIKDENILIDL 173
Query: 245 VYHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHAS 304
++ DFG ++ + P+ D GT +++ PE S H
Sbjct: 174 RRGCAKLIDFGSGALLHDE-PYTD-------------FDGTRVYSPPEWI-----SRHQY 214
Query: 305 NEQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIYGWIHEY 364
+ P VWSLGI +Y ++ +PF + E L + PD
Sbjct: 215 HALP--ATVWSLGILLYDMVCGDIPFERDQEILEAELHFPAHVSPDCC-----------A 261
Query: 365 VVNRMLSKNTASRPTTSNIL 384
++ R L+ +SRP+ IL
Sbjct: 262 LIRRCLAPKPSSRPSLEEIL 281
>CE02377 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 1211
Score = 73.2 bits (178), Expect = 8e-13
Identities = 66/273 (24%), Positives = 118/273 (43%), Gaps = 61/273 (22%)
Query: 68 KFVNQYRIGERLGCGQFGTVYKGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESIS 127
KF Y++ + LG G+FG VY + +K F+ I
Sbjct: 40 KFDTLYQVTKLLGDGKFGKVYC------------VIEKETGKEFAAKFIK---------- 77
Query: 128 GDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRE 187
+ E + +++ E + ++L HP + Q+ + + +D + LI + GEL
Sbjct: 78 ---IRKEADRAEVEREVSILTQLRHPRIAQIYDAFYTTTNDVV-LIMEIVRGGEL----- 128
Query: 188 SKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNIL-LDPVY 246
FD + + +S+ +L V ++ + + Y+ Q I+H D+KP+NI+ +
Sbjct: 129 --FDRVAE-ESYVLSELA-----VVMIICQLCEAIDYIHKQNILHLDVKPENIMCVSLTG 180
Query: 247 HSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNE 306
+ +++ DFG + DG +EL + GTP F APE+ F + H
Sbjct: 181 NRIKLIDFGLAR-------HYDGT------QELKYMAGTPEFAAPEVIKFEKLDYHT--- 224
Query: 307 QPFKIDVWSLGITVYAILYNVLPFWGETEFDTY 339
D+WS+G+ Y +L PF G+ +TY
Sbjct: 225 -----DMWSIGVITYILLSGYSPFLGDNLGETY 252
>7293666 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 576
Score = 73.2 bits (178), Expect = 8e-13
Identities = 68/263 (25%), Positives = 113/263 (42%), Gaps = 50/263 (19%)
Query: 126 ISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWS 185
+S ++I K E + LNHPN+++ + S I+++ L
Sbjct: 56 VSKKLMIKHNQKEKTAQEITIHRSLNHPNIVKFHNYFED--SQNIYIVLELC-------K 106
Query: 186 RESKFDLIEQWKSFYRGQLDSVEEFAVKV-LGDISNGLQYLQGQGIIHRDLKPQNILLDP 244
+ S +L ++ KS + EF + + I G++YL IIHRDLK N+ L+
Sbjct: 107 KRSMMELHKRRKS--------ITEFECRYYIYQIIQGVKYLHDNRIIHRDLKLGNLFLND 158
Query: 245 VYHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNK-IVGTPLFTAPELCNFAEGSAHA 303
+ H ++I DFG + + +E E K + GTP + APE+
Sbjct: 159 LLH-VKIGDFGLATRIE-------------YEGERKKTLCGTPNYIAPEILT-------- 196
Query: 304 SNEQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLI--CHRQLKPDVHNSSNIYGWI 361
F++D+WS+G +Y +L PF +T DTY+ I C ++ + +
Sbjct: 197 KKGHSFEVDIWSIGCVMYTLLVGQPPFETKTLKDTYSKIKKCEYRVPSYLRKPA------ 250
Query: 362 HEYVVNRMLSKNTASRPTTSNIL 384
+V ML N SRP +L
Sbjct: 251 -ADMVIAMLQPNPESRPAIGQLL 272
>SPAC890.03 [T] KOG0583 Serine/threonine protein kinase
Length = 672
Score = 72.8 bits (177), Expect = 1e-12
Identities = 77/267 (28%), Positives = 116/267 (42%), Gaps = 75/267 (28%)
Query: 70 VNQYRIGERLGCGQFGTVYKGH---TTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESI 126
V YRI +G G FG VY T KVV +K+ R ++I
Sbjct: 28 VGTYRIESVVGEGSFGKVYLAAHLLTNTKVV-------------------LKSSCRKQAI 68
Query: 127 SGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGEL-QW- 184
+L E++ + +L HPN+ +L E + + D+I+L GEL W
Sbjct: 69 ---ILAREIHHHR---------RLLHPNITRLYEVVCT--EDRIYLAMEYCPNGELYDWV 114
Query: 185 SRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDP 244
+RE + D E+ +++ + +QYL QG +HRDLK +NI LD
Sbjct: 115 AREKRLD----------------EKTTCRIMWQLCCAIQYLHRQGCVHRDLKLENIFLDK 158
Query: 245 VYHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKE-LNKIVGTPLFTAPELCNFAEGSAHA 303
Y ++++ DFG S R D + +N GT + APEL +G +
Sbjct: 159 AY-NVKLGDFGFS------------RDSDCSRRTFMNTRCGTVAYCAPEL---VQGHKYI 202
Query: 304 SNEQPFKIDVWSLGITVYAILYNVLPF 330
+D+WSLGI +YA+L LPF
Sbjct: 203 GE----CVDIWSLGIIMYALLIGRLPF 225
>SPAC57A10.02 [D] KOG0588 Serine/threonine protein kinase
Length = 775
Score = 72.8 bits (177), Expect = 1e-12
Identities = 67/247 (27%), Positives = 111/247 (44%), Gaps = 44/247 (17%)
Query: 138 SKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESKFDLIEQWK 197
++I E + + HPNV+QL++ + + +Q++++ GEL FD + +
Sbjct: 53 ARIEGELVLLRLIEHPNVLQLIDVISA--QEQLFVVVEYMPGGEL-------FDCMLRKG 103
Query: 198 SFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYHSLRISDFG-C 256
SF E+ K L I GL+Y I HRDLKP+N+ LD + S++I +FG
Sbjct: 104 SF-------TEQDTAKFLWQILCGLEYCHKLHICHRDLKPENLYLD-AHGSIKIGEFGMA 155
Query: 257 SLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQPFKIDVWSL 316
S+ P KL L G+P + +PE+ AS D+WS
Sbjct: 156 SIQQPGKL--------------LQTSCGSPHYASPEIIMGRSYDGCAS-------DIWSC 194
Query: 317 GITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIYGWIHEYVVNRMLSKNTAS 376
GI +A+L LPF + +C Q + + S ++++ RML ++++
Sbjct: 195 GIIFFALLTGKLPFDDDNIRSLLLKVCQGQFEMPSNISPQA-----QHLLYRMLDVDSST 249
Query: 377 RPTTSNI 383
R T I
Sbjct: 250 RITMEQI 256
>Hs4759050 [T] KOG0603 Ribosomal protein S6 kinase
Length = 740
Score = 72.8 bits (177), Expect = 1e-12
Identities = 78/337 (23%), Positives = 142/337 (41%), Gaps = 63/337 (18%)
Query: 12 ESIRIQPMSTDPESYFQIIDEQQKKLELGVISKTKIIERYVXXXXXXXXXQEEHAQKFVN 71
+ + ++ S E+ QI+DE + E+ ++ E + +E H + +
Sbjct: 11 QKMAVESPSDSAENGQQIMDEPMGEEEINPQTE----EVSIKEIAITHHVKEGHEKADPS 66
Query: 72 QYRIGERLGCGQFGTVYKGHTTGKVVAIKQIYKKPMNSPFSMSLIMK-TMKRYESISGDV 130
Q+ + + LG G FG KV +K+I ++M ++ K T+K + +
Sbjct: 67 QFELLKVLGQGSFG---------KVFLVKKISGSDARQLYAMKVLKKATLKVRDRV---- 113
Query: 131 LIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESKF 190
+ + E + ++NHP +++L + +++LI G+L +
Sbjct: 114 --------RTKMERDILVEVNHPFIVKLHYAFQT--EGKLYLILDFLRGGDLFTRLSKEV 163
Query: 191 DLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYHSLR 250
E+ FY L +++ L +L GII+RDLKP+NILLD H ++
Sbjct: 164 MFTEEDVKFY--------------LAELALALDHLHSLGIIYRDLKPENILLDEEGH-IK 208
Query: 251 ISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQPFK 310
++DFG S + EK+ GT + APE+ N + A
Sbjct: 209 LTDFGLS------------KESIDHEKKAYSFCGTVEYMAPEVVNRRGHTQSA------- 249
Query: 311 IDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQL 347
D WS G+ ++ +L LPF G+ +T +I +L
Sbjct: 250 -DWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKL 285
Score = 64.3 bits (155), Expect = 4e-10
Identities = 72/271 (26%), Positives = 108/271 (39%), Gaps = 77/271 (28%)
Query: 68 KFVNQYRIGERLGCGQFGTVYKGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESIS 127
+F + Y + E +G G + K+ K N F++ +I K+ KR +
Sbjct: 417 QFTDGYEVKEDIGVGSYSVC------------KRCIHKATNMEFAVKIIDKS-KRDPTEE 463
Query: 128 GDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRE 187
++L+ HPN+I L + D ++++ L GEL
Sbjct: 464 IEILLRYGQ---------------HPNIITLKDVYDD--GKYVYVVTELMKGGEL----- 501
Query: 188 SKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILL----- 242
D I + K F E A VL I+ ++YL QG++HRDLKP NIL
Sbjct: 502 --LDKILRQKFFS-------EREASAVLFTITKTVEYLHAQGVVHRDLKPSNILYVDESG 552
Query: 243 DPVYHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKEL---NKIVGTPLFTAPELCNFAEG 299
+P S+RI DFG F K+L N ++ TP +TA NF
Sbjct: 553 NP--ESIRICDFG-------------------FAKQLRAENGLLMTPCYTA----NFVAP 587
Query: 300 SAHASNEQPFKIDVWSLGITVYAILYNVLPF 330
D+WSLG+ +Y +L PF
Sbjct: 588 EVLKRQGYDAACDIWSLGVLLYTMLTGYTPF 618
>At1g63700 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 883
Score = 72.8 bits (177), Expect = 1e-12
Identities = 77/320 (24%), Positives = 142/320 (44%), Gaps = 72/320 (22%)
Query: 71 NQYRIGERLGCGQFGTVYKGHTT--GKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISG 128
++++ G LG G FG VY G + G++ A+K++ +L K ES
Sbjct: 398 SRWKKGRLLGMGSFGHVYLGFNSESGEMCAMKEV-----------TLCSDDPKSRES--- 443
Query: 129 DVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRES 188
++ E V S+L H N++Q D++++ G +
Sbjct: 444 --------AQQLGQEISVLSRLRHQNIVQYYG--SETVDDKLYIYLEYVSGGSI------ 487
Query: 189 KFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYHS 248
+ L++++ F +++ + ++L +GL YL + +HRD+K NIL+DP +
Sbjct: 488 -YKLLQEYGQFGE---NAIRNYTQQIL----SGLAYLHAKNTVHRDIKGANILVDP-HGR 538
Query: 249 LRISDFGCSLIVPSK---LPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASN 305
++++DFG + + ++ L FK G+P + APE+ + GS A
Sbjct: 539 VKVADFGMAKHITAQSGPLSFK----------------GSPYWMAPEVIKNSNGSNLA-- 580
Query: 306 EQPFKIDVWSLGITVYAILYNVLPFWGETE-FDTYNLICHRQLKPDVHNSSNIYGWIHEY 364
+D+WSLG TV + P W + E I + + PD+ + + G +
Sbjct: 581 -----VDIWSLGCTVLE-MATTKPPWSQYEGVPAMFKIGNSKELPDIPDHLSEEG---KD 631
Query: 365 VVNRMLSKNTASRPTTSNIL 384
V + L +N A+RPT + +L
Sbjct: 632 FVRKCLQRNPANRPTAAQLL 651
>At1g12680 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 470
Score = 72.8 bits (177), Expect = 1e-12
Identities = 80/327 (24%), Positives = 138/327 (41%), Gaps = 74/327 (22%)
Query: 62 QEEHAQKFVNQYRIGERLGCGQFGTVYKGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMK 121
Q K + Y G +G G+FG+V +I K N KT+K
Sbjct: 96 QTGRKNKIDDDYVFGRNIGKGKFGSV-------------RICKSRKNGT---EFACKTLK 139
Query: 122 R-YESISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLG 180
+ E++ +V IM+ HP V+ L + SD L+ L G
Sbjct: 140 KGEETVHREVEIMQ-------------HLSGHPRVVTLHAVYEE--SDCFHLVMELCSGG 184
Query: 181 ELQWSRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNI 240
L I+Q R E+ A + D+ + Y G++HRD+KP+NI
Sbjct: 185 RL----------IDQMVKVGRYS----EQRAANIFKDLMLVINYCHEMGVVHRDIKPENI 230
Query: 241 LLDPVYHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELC--NFAE 298
LL ++++DFG ++ + + L+ + G+P + APE+ N++E
Sbjct: 231 LLTAA-GKIQLADFGLAMRIAKG-------------QTLSGLAGSPAYVAPEVLSENYSE 276
Query: 299 GSAHASNEQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIY 358
K+DVWS G+ +YA+L VLPF G++ + I + +L + ++
Sbjct: 277 -----------KVDVWSAGVLLYALLSGVLPFKGDSLDAIFEAIKNVKLDFNTGVWESVS 325
Query: 359 GWIHEYVVNRMLSKNTASRPTTSNILR 385
+ ++ RML++ ++R T +LR
Sbjct: 326 KPARD-LLARMLTREESARITADEVLR 351
>7296450 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 769
Score = 72.8 bits (177), Expect = 1e-12
Identities = 83/317 (26%), Positives = 130/317 (40%), Gaps = 67/317 (21%)
Query: 70 VNQYRIGERLGCGQFGTVYKGHT--TGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESIS 127
+ Y + LG G F TVYK T + VAIK I KK I
Sbjct: 11 IEDYEVQHLLGKGGFATVYKARCLHTHQDVAIKMIDKK-------------------LIQ 51
Query: 128 GDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRE 187
G L +++R E + S+L HP+V+QL ++ ++L+ LA GEL
Sbjct: 52 GTGL-----TNRVRQEVEIHSRLKHPSVLQLYTFFQD--ANYVYLVLELAHNGELH---- 100
Query: 188 SKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYH 247
++ + E A +L + GL YL I+HRD+ N+LL H
Sbjct: 101 -------RYMNHIARPFTETE--AASILKQVVAGLLYLHSHNIMHRDISLSNLLLSREMH 151
Query: 248 SLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQ 307
++I+DFG L K P ++ + GTP + +PE+ + S+
Sbjct: 152 -VKIADFG--LATQLKRP----------DERHMTMCGTPNYISPEVV------SRTSHGL 192
Query: 308 PFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIYGWIHEYVVN 367
P DVWS+G +Y +L PF + T N + + H S + + ++N
Sbjct: 193 P--ADVWSVGCMLYTLLVGRPPFETDAVQSTLNKVVMSEYIMPAHLS-----YEAQDLIN 245
Query: 368 RMLSKNTASRPTTSNIL 384
++L K R T +L
Sbjct: 246 KLLKKLPHERITLEAVL 262
>SPBC1604.14c [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 658
Score = 72.4 bits (176), Expect = 1e-12
Identities = 69/313 (22%), Positives = 130/313 (41%), Gaps = 65/313 (20%)
Query: 73 YRIGERLGCGQFGTVYKGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISGDVLI 132
YR ++G G G VY G +++ K MN + + E I ++L+
Sbjct: 386 YRNFVKIGQGASGDVYSARQVGTNLSVAI---KKMN--------INQQPKKEFIVNEILV 434
Query: 133 MEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESKFDL 192
M+ + +H N++ ++ Y ++W++ +++ R
Sbjct: 435 MKSH--------------HHKNIVNFIDTFF--YKSELWMV--------MEYMRGGSLTE 470
Query: 193 IEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYHSLRIS 252
+ + GQ+ ++ + ++ GLQ+L GI+HRD+K NILL + ++++
Sbjct: 471 VVTNNTLSEGQIAAICKETLE-------GLQHLHENGIVHRDIKSDNILLS-LQGDIKLT 522
Query: 253 DFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQPFKID 312
DFG + S + + +VGTP + APE+ E FK+D
Sbjct: 523 DFGFCAQIDSNM------------TKRTTMVGTPYWMAPEVV--------TRKEYGFKVD 562
Query: 313 VWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIYGWIHEYVVNRMLSK 372
VWSLGI ++ P+ E LI P + + H++ +++ L+
Sbjct: 563 VWSLGIMAIEMVEGEPPYLNENPLRALYLIATIG-TPKISRPELLSSVFHDF-LSKSLTV 620
Query: 373 NTASRPTTSNILR 385
N RP++ +LR
Sbjct: 621 NPKQRPSSGELLR 633
>SPAC23C11.16 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 683
Score = 72.4 bits (176), Expect = 1e-12
Identities = 58/193 (30%), Positives = 97/193 (50%), Gaps = 37/193 (19%)
Query: 139 KIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESKFDLIEQWKS 198
K+ E V ++HPN++ ++C + S I+LI L +S +L+ + K
Sbjct: 84 KLFGEIKVHQSMSHPNIVGFIDCFED--STNIYLILELC-------EHKSLMELLRKRKQ 134
Query: 199 FYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYHSLRISDFGCSL 258
+ V +++LG L+Y+ + +IHRDLK NI+LD ++++I DFG +
Sbjct: 135 LTEPE---VRYLMMQILG----ALKYMHKKRVIHRDLKLGNIMLDES-NNVKIGDFGLAA 186
Query: 259 IVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPE-LCNFAEGSAHASNEQPFKIDVWSLG 317
+ L D E+++ I GTP + APE L N EG + F++D+WS G
Sbjct: 187 L-----------LMDDEERKMT-ICGTPNYIAPEILFNSKEGHS-------FEVDLWSAG 227
Query: 318 ITVYAILYNVLPF 330
+ +YA+L PF
Sbjct: 228 VVMYALLIGKPPF 240
>Hs20149547 [T] KOG0603 Ribosomal protein S6 kinase
Length = 735
Score = 72.4 bits (176), Expect = 1e-12
Identities = 65/255 (25%), Positives = 115/255 (44%), Gaps = 50/255 (19%)
Query: 94 GKVVAIKQIYKKPMNSPFSMSLIMK-TMKRYESISGDVLIMEMNVSKIRWECFVTSKLNH 152
GKV ++++ + ++M ++ K T+K + + + + E + + +NH
Sbjct: 74 GKVFLVRKVTRPDSGHLYAMKVLKKATLKVRDRV------------RTKMERDILADVNH 121
Query: 153 PNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESKFDLIEQWKSFYRGQLDSVEEFAV 212
P V++L + +++LI G+L + E+ FY
Sbjct: 122 PFVVKLHYAFQT--EGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFY------------ 167
Query: 213 KVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYHSLRISDFGCSLIVPSKLPFKDGRLQ 272
L +++ GL +L GII+RDLKP+NILLD H ++++DFG S
Sbjct: 168 --LAELALGLDHLHSLGIIYRDLKPENILLDEEGH-IKLTDFGLSKEAID---------- 214
Query: 273 DLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQPFKIDVWSLGITVYAILYNVLPFWG 332
EK+ GT + APE+ N +G +H++ D WS G+ ++ +L LPF G
Sbjct: 215 --HEKKAYSFCGTVEYMAPEVVN-RQGHSHSA-------DWWSYGVLMFEMLTGSLPFQG 264
Query: 333 ETEFDTYNLICHRQL 347
+ +T LI +L
Sbjct: 265 KDRKETMTLILKAKL 279
Score = 62.0 bits (149), Expect = 2e-09
Identities = 60/187 (32%), Positives = 78/187 (41%), Gaps = 49/187 (26%)
Query: 152 HPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESKFDLIEQWKSFYRGQLDSVEEFA 211
HPN+I L + D ++L+ L GEL D I + K F E A
Sbjct: 469 HPNIITLKDVYDD--GKHVYLVTELMRGGEL-------LDKILRQKFFS-------EREA 512
Query: 212 VKVLGDISNGLQYLQGQGIIHRDLKPQNILL-----DPVYHSLRISDFGCSLIVPSKLPF 266
VL I ++YL QG++HRDLKP NIL +P LRI DFG
Sbjct: 513 SFVLHTIGKTVEYLHSQGVVHRDLKPSNILYVDESGNP--ECLRICDFG----------- 559
Query: 267 KDGRLQDLFEKEL---NKIVGTPLFTAPELCNFAEGSAHASNEQPFKIDVWSLGITVYAI 323
F K+L N ++ TP +TA NF D+WSLGI +Y +
Sbjct: 560 --------FAKQLRAENGLLMTPCYTA----NFVAPEVLKRQGYDEGCDIWSLGILLYTM 607
Query: 324 LYNVLPF 330
L PF
Sbjct: 608 LAGYTPF 614
>YPL150w [T] KOG0583 Serine/threonine protein kinase
Length = 901
Score = 72.0 bits (175), Expect = 2e-12
Identities = 66/247 (26%), Positives = 110/247 (43%), Gaps = 36/247 (14%)
Query: 144 CFVTSKLNHPNVIQLL---ECLDSPYSDQIW--LIQPLAVLGELQWSRESKFDLIEQWKS 198
C TS N PN+++ + D PY +++ ++ V L++ +L + S
Sbjct: 68 CLKTSDKNDPNIVREVFYHRQFDFPYITKLYEVIVTESKVWMALEYCPGK--ELYDHLLS 125
Query: 199 FYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYHSLRISDFGCSL 258
R L E + IS + Y +HRDLK +NILLD ++ +++DFG +
Sbjct: 126 LRRISLLECGE----LFAQISGAVYYAHSMHCVHRDLKLENILLDKNGNA-KLTDFGFTR 180
Query: 259 IVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQPFKIDVWSLGI 318
+K L + GT ++ APEL FKID+WSLG+
Sbjct: 181 ECMTKTT-------------LETVCGTTVYMAPELIE-------RRTYDGFKIDIWSLGV 220
Query: 319 TVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIYGWIHEYVVNRMLSKNTASRP 378
+Y ++ LPF + E T I + + K D + + +++R+L+KN RP
Sbjct: 221 ILYTLITGYLPFDDDDEAKTKWKIVNEEPKYD----AKVIPDDARDLISRLLAKNPGERP 276
Query: 379 TTSNILR 385
+ S +LR
Sbjct: 277 SLSQVLR 283
>YOR233w [T] KOG0583 Serine/threonine protein kinase
Length = 800
Score = 72.0 bits (175), Expect = 2e-12
Identities = 78/279 (27%), Positives = 121/279 (42%), Gaps = 57/279 (20%)
Query: 62 QEEHAQKFVNQYRIGERLGCGQFGTVYKGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMK 121
Q +HA Y IG LG G+FG V G T K + ++ K+ ++ LI +
Sbjct: 37 QRKHAT--FGPYIIGSTLGEGEFGKVKLGWT--KASSSNEVPKQ-----VAIKLIRRDTI 87
Query: 122 RYESISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGE 181
+ ++ + E+N K L HPN+I L E L + S I ++ GE
Sbjct: 88 KKDADKEIKIYREINALK---------HLTHPNIIYLEEVLQN--SKYIGIVLEFVSGGE 136
Query: 182 LQWSRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNIL 241
+ K L E A ++ + +G+ Y+ +G++HRDLK +N+L
Sbjct: 137 FYKYIQRKRRL--------------KESSACRLFAQLISGVNYMHYKGLVHRDLKLENLL 182
Query: 242 LDPVYHSLRISDFGCSLIVPSKLPFKDGRLQDLFE-KELNKI-VGTPLFTAPELCNFAEG 299
LD + +L I+DFG + + FE EL K G+P + APEL
Sbjct: 183 LDK-HENLVITDFGF--------------VNEFFEDNELMKTSCGSPCYAAPELV----- 222
Query: 300 SAHASNEQPFKIDVWSLGITVYAILYNVLPFWGETEFDT 338
+ K DVWS G+ +YA+L LP+ + E T
Sbjct: 223 -VSTKAYEARKADVWSCGVILYAMLAGYLPWDDDHENPT 260
>SPCC576.15c [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 592
Score = 72.0 bits (175), Expect = 2e-12
Identities = 77/291 (26%), Positives = 128/291 (43%), Gaps = 56/291 (19%)
Query: 68 KFVNQYRIGERLGCGQFGTVYKG--HTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYES 125
K V+ ++ GE LG G + TV ++T + AIK + K+ +I + ++Y +
Sbjct: 94 KRVSDFKFGEILGEGSYSTVLTATENSTKREYAIKVLDKR--------HIIKEKKEKYVN 145
Query: 126 ISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWS 185
I + L C ++ HP I+L ++ ++ + LA GEL
Sbjct: 146 IEKEAL------------CILSK---HPGFIKLFYTFQDAHN--LYFVLSLARNGEL--- 185
Query: 186 RESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPV 245
D I + F E A I + + Y+ G+G+IHRDLKP+NILLD
Sbjct: 186 ----LDYINKLGRFN-------EICAQYYAALIVDSIDYMHGRGVIHRDLKPENILLDDN 234
Query: 246 YHSLRISDFGCSLIVPSK--LPFKDGRLQDLFEKELNKIVGTPLFTAPE-LCNFAEGSAH 302
+ +I+DFG + I+ S +D D + VGT + +PE L + G+A
Sbjct: 235 MRT-KITDFGSAKILNSSHGSHEEDTHHADKPQAHSRSFVGTARYVSPEVLSDKIAGTAS 293
Query: 303 ASNEQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICH--RQLKPDV 351
D+W+ G ++ +L PF E+ T+ I H ++ PD+
Sbjct: 294 ---------DIWAFGCILFQMLAGKPPFVAGNEYLTFQSILHLSYEIPPDI 335
>Hs14776113 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 424
Score = 72.0 bits (175), Expect = 2e-12
Identities = 69/254 (27%), Positives = 110/254 (43%), Gaps = 56/254 (22%)
Query: 143 ECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESKFDLIEQWKSFYRG 202
E V ++ H N+IQL+E ++ ++++++ LA GEL FD I SF
Sbjct: 143 ELRVLRRVRHANIIQLVEVFET--QERVYMVMELATGGEL-------FDRIIAKGSF--- 190
Query: 203 QLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYH-----SLRISDFGCS 257
E A +VL + +G++YL GI HRDLKP+N+L YH + I+DFG
Sbjct: 191 ----TERDATRVLQMVLDGVRYLHALGITHRDLKPENLL---YYHPGTDSKIIITDFG-- 241
Query: 258 LIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQPFKIDVWSLG 317
+ S D L + GTP + APE+ +D+W+LG
Sbjct: 242 --LASARKKGDDCL-------MKTTCGTPEYIAPEVL--------VRKPYTNSVDMWALG 284
Query: 318 ITVYAILYNVLPFWGETEFDTYNLICHRQLK------PDVHNSSNIYGWIHEYVVNRMLS 371
+ Y +L +PF + Y I + P V N + + ++R+L+
Sbjct: 285 VIAYILLSGTMPFEDDNRTRLYRQILRGKYSYSGEPWPSVSNLAKDF-------IDRLLT 337
Query: 372 KNTASRPTTSNILR 385
+ +R T LR
Sbjct: 338 VDPGARMTALQALR 351
>YCR091w [R] KOG0610 Putative serine/threonine protein kinase
Length = 720
Score = 71.6 bits (174), Expect = 2e-12
Identities = 81/309 (26%), Positives = 129/309 (41%), Gaps = 62/309 (20%)
Query: 79 LGCGQFGTVY--KGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISGDVLIMEMN 136
LG G G VY + T ++ A+K + K M I
Sbjct: 330 LGQGDVGKVYLMRERDTNQIFALKVLNKHEM------------------------IKRKK 365
Query: 137 VSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESKFDLIEQW 196
+ ++ E + + +HP ++ L + D ++L + GE F ++
Sbjct: 366 IKRVLTEQEILATSDHPFIVTLYHSFQT--KDYLYLCMEYCMGGEF-------FRALQTR 416
Query: 197 KSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYHSLRISDFGC 256
KS EE A ++ L+YL G I+RDLKP+NILL H + +SDF
Sbjct: 417 KSKC-----IAEEDAKFYASEVVAALEYLHLLGFIYRDLKPENILLHQSGHVM-LSDFDL 470
Query: 257 SL-IVPSKLP-FKDGRLQDLF----EKELNKIVGTPLFTAPELCNFAEGSAHASNEQPFK 310
S+ SK P KD D N VGT + APE+ G+ H +
Sbjct: 471 SIQATGSKKPTMKDSTYLDTKICSDGFRTNSFVGTEEYLAPEVIR---GNGHTA-----A 522
Query: 311 IDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLK--PDVHNSSNIYGWIHEYVVNR 368
+D W+LGI +Y +L+ PF G+ +T++ I + +K D S N + ++ +
Sbjct: 523 VDWWTLGILIYEMLFGCTPFKGDNSNETFSNILTKDVKFPHDKEVSKNC-----KDLIKK 577
Query: 369 MLSKNTASR 377
+L+KN A R
Sbjct: 578 LLNKNEAKR 586
>Hs7019543 [T] KOG0582 Ste20-like serine/threonine protein kinase
Length = 547
Score = 71.6 bits (174), Expect = 2e-12
Identities = 67/258 (25%), Positives = 111/258 (42%), Gaps = 30/258 (11%)
Query: 134 EMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESKFDLI 193
+ ++ ++ E S+ +HPNV+ D++WL+ L G S D+I
Sbjct: 102 QTSMDELLKEIQAMSQCSHPNVVTYYTSF--VVKDELWLVMKLLSGG-------SMLDII 152
Query: 194 EQWKSFYRGQLDSVEEFAVK-VLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYHSLRIS 252
+ + + +EE + +L ++ GL YL G IHRDLK NILL S++I+
Sbjct: 153 KYIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGE-DGSVQIA 211
Query: 253 DFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQPFKID 312
DFG S + + +++ F VGTP + APE+ G FK D
Sbjct: 212 DFGVSAFLATGGDVTRNKVRKTF-------VGTPCWMAPEVMEQVRG-------YDFKAD 257
Query: 313 VWSLGITVYAILYNVLPFWGETEFDTYNLICHRQ---LKPDVHNSSNI--YGWIHEYVVN 367
+WS GIT + P+ L L+ V + + YG +++
Sbjct: 258 MWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDKEMMKKYGKSFRKLLS 317
Query: 368 RMLSKNTASRPTTSNILR 385
L K+ + RPT + +L+
Sbjct: 318 LCLQKDPSKRPTAAELLK 335
>Hs14754789 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 257
Score = 71.6 bits (174), Expect = 2e-12
Identities = 71/268 (26%), Positives = 112/268 (41%), Gaps = 76/268 (28%)
Query: 77 ERLGCGQFGTVYKGHT---TGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISGDVLIM 133
ERLG G + TVYK + T +VVAIK + KK +N
Sbjct: 61 ERLGSGTYATVYKAYAKKDTREVVAIKCVAKKSLN------------------------- 95
Query: 134 EMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESKFDLI 193
+ +V + E + + HP+++QL + SD I+LI G+L ++ L
Sbjct: 96 KASVENLLTEIEILKGIRHPHIVQLKDFQWD--SDNIYLIMEFCAGGDLSRFIHTRRILP 153
Query: 194 EQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYH-SLRIS 252
E+ + QL S LQ+L + I H DLKPQNILL + L+++
Sbjct: 154 EKVARVFMQQLASA--------------LQFLHERNISHLDLKPQNILLSSLEKPHLKLA 199
Query: 253 DFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQPFKID 312
DFG P+ E + + G+PL+ APE+ + ++D
Sbjct: 200 DFG---FAQHMSPW----------DEKHVLRGSPLYMAPEMV--------CQRQYDARVD 238
Query: 313 VWSLGITVYAILYNVLPFWGETEFDTYN 340
+WS+G+ +Y GET F ++
Sbjct: 239 LWSMGVILY----------GETSFPCFS 256
>At4g04700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 347
Score = 71.6 bits (174), Expect = 2e-12
Identities = 74/323 (22%), Positives = 132/323 (39%), Gaps = 76/323 (23%)
Query: 73 YRIGERLGCGQFGTVYK--GHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISGDV 130
Y +GE LG G FG K +TGK A K I K + + + ++ + +SG+
Sbjct: 28 YILGEELGRGNFGLTRKCVEKSTGKTFACKTILKTKLKDEECEEDVKREIRIMKQLSGE- 86
Query: 131 LIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESKF 190
PN+++ + D + ++ GEL + +
Sbjct: 87 ----------------------PNIVEFKNAYED--KDSVHIVMEYCGGGELYDKILALY 122
Query: 191 DLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILL--DPVYHS 248
D+ + + E+ A ++ I N ++ G++HRDLKP+N LL + +
Sbjct: 123 DVGKSYS----------EKEAAGIIRSIVNVVKNCHYMGVMHRDLKPENFLLTSNDDNAT 172
Query: 249 LRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQP 308
+++ DFGCS+ + ++D + G+ + APE+ G
Sbjct: 173 VKVIDFGCSVFIEEGKVYQD-------------LAGSDYYIAPEVLQGNYGK-------- 211
Query: 309 FKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPD-------VHNSSNIYGWI 361
+ D+WS GI +Y +L PF E E +N I + L+ D + +S I
Sbjct: 212 -EADIWSAGIILYILLCGKSPFVKEPEGQMFNEI--KSLEIDYSEEPWPLRDSRAI---- 264
Query: 362 HEYVVNRMLSKNTASRPTTSNIL 384
++V RML +N R + + +L
Sbjct: 265 --HLVKRMLDRNPKERISAAEVL 285
>YJL164c [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 397
Score = 71.2 bits (173), Expect = 3e-12
Identities = 73/278 (26%), Positives = 121/278 (43%), Gaps = 66/278 (23%)
Query: 73 YRIGERLGCGQFGTVY--KGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISGDV 130
++I LG G FG V+ + G+ A+K + K+ I+ +K+ E + +
Sbjct: 87 FQILRTLGTGSFGRVHLIRSRHNGRYYAMKVLKKE----------IVVRLKQVEHTNDER 136
Query: 131 LIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESKF 190
L++ + + HP +I++ + QI++I GEL F
Sbjct: 137 LMLSI--------------VTHPFIIRMWGTFQD--AQQIFMIMDYIEGGEL-------F 173
Query: 191 DLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYHSLR 250
L+ + + F + V +F ++ L+YL + II+RDLKP+NILLD H ++
Sbjct: 174 SLLRKSQRFP----NPVAKFYA---AEVCLALEYLHSKDIIYRDLKPENILLDKNGH-IK 225
Query: 251 ISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQPFK 310
I+DFG + VP + GTP + APE+ S N+
Sbjct: 226 ITDFGFAKYVPD---------------VTYTLCGTPDYIAPEVV-----STKPYNK---S 262
Query: 311 IDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLK 348
ID WS GI +Y +L PF+ TY I + +L+
Sbjct: 263 IDWWSFGILIYEMLAGYTPFYDSNTMKTYEKILNAELR 300
>Hs7662388 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 632
Score = 71.2 bits (173), Expect = 3e-12
Identities = 74/280 (26%), Positives = 129/280 (45%), Gaps = 73/280 (26%)
Query: 70 VNQYRIGERLGCGQFGTVYKGHT--TGKVVAIKQIYKKPMNSPFSMSLI-MKTMKRYESI 126
+N+Y +LG G +G+V G + +G+++AIK++ +K + M+L +K++K
Sbjct: 1 MNRYTTIRQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNLREVKSLK----- 55
Query: 127 SGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSR 186
KLNH NV++L E + +D ++ I ++ +
Sbjct: 56 ----------------------KLNHANVVKLKEVIRE--NDHLYFI--------FEYMK 83
Query: 187 ESKFDLIEQWKSFYRGQLDSVEEFAVK-VLGDISNGLQYLQGQGIIHRDLKPQNIL-LDP 244
E+ + LI++ + E A++ ++ I GL ++ G HRDLKP+N+L + P
Sbjct: 84 ENLYQLIKERNKLF-------PESAIRNIMYQILQGLAFIHKHGFFHRDLKPENLLCMGP 136
Query: 245 VYHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHAS 304
++I+DFG + + SK P+ D V T + APE+ S
Sbjct: 137 --ELVKIADFGLAREIRSKPPYTD-------------YVSTRWYRAPEV-------LLRS 174
Query: 305 NEQPFKIDVWSLGITVYAILYNVLP-FWGETEFDTYNLIC 343
IDVW++G + A +Y + P F G +E DT IC
Sbjct: 175 TNYSSPIDVWAVG-CIMAEVYTLRPLFPGASEIDTIFKIC 213
>Hs7661974 [T] KOG0583 Serine/threonine protein kinase
Length = 651
Score = 71.2 bits (173), Expect = 3e-12
Identities = 74/278 (26%), Positives = 117/278 (41%), Gaps = 65/278 (23%)
Query: 68 KFVNQYRIGERLGCGQFGTVYKGH--TTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYES 125
+ + Y + E +G G F V TG++VAIK + K + S
Sbjct: 6 ELLKYYELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTLGS---------------- 49
Query: 126 ISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWS 185
++ +I+ E L H ++ QL L++ +++I+++ GEL
Sbjct: 50 ----------DLPRIKTEIEALKNLRHQHICQLYHVLET--ANKIFMVLEYCPGGEL--- 94
Query: 186 RESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPV 245
FD I S EE V V I + + Y+ QG HRDLKP+N+L D
Sbjct: 95 ----FDYIISQDRL------SEEETRV-VFRQIVSAVAYVHSQGYAHRDLKPENLLFDE- 142
Query: 246 YHSLRISDFG-CSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHAS 304
YH L++ DFG C+ +K + L G+ + APEL +G ++
Sbjct: 143 YHKLKLIDFGLCAKPKGNK------------DYHLQTCCGSLAYAAPEL---IQGKSYLG 187
Query: 305 NEQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLI 342
+E DVWS+GI +Y ++ LPF + Y I
Sbjct: 188 SE----ADVWSMGILLYVLMCGFLPFDDDNVMALYKKI 221
>Hs4505695 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 556
Score = 71.2 bits (173), Expect = 3e-12
Identities = 72/273 (26%), Positives = 117/273 (42%), Gaps = 63/273 (23%)
Query: 67 QKFVNQYRIGERLGCGQFGTVYKGH--TTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYE 124
+K ++ G+ LG G F TV T + AIK + K+
Sbjct: 76 KKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRH------------------ 117
Query: 125 SISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQW 184
+I E V + E V S+L+HP ++L ++++ A GEL
Sbjct: 118 ------IIKENKVPYVTRERDVMSRLDHPFFVKLYFTFQD--DEKLYFGLSYAKNGELLK 169
Query: 185 SRESKFDLIEQWKSFYRGQLDSVEEFAVKVL-GDISNGLQYLQGQGIIHRDLKPQNILLD 243
Y ++ S +E + +I + L+YL G+GIIHRDLKP+NILL+
Sbjct: 170 ---------------YIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLN 214
Query: 244 PVYHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHA 303
H ++I+DFG + ++ + + N VGT + +PEL E SA
Sbjct: 215 EDMH-IQITDFGTAKVLSPESK----------QARANSFVGTAQYVSPEL--LTEKSACK 261
Query: 304 SNEQPFKIDVWSLGITVYAILYNVLPFWGETEF 336
S+ D+W+LG +Y ++ + PF E+
Sbjct: 262 SS------DLWALGCIIYQLVAGLPPFRAGNEY 288
>CE28218 [D] KOG0588 Serine/threonine protein kinase
Length = 914
Score = 71.2 bits (173), Expect = 3e-12
Identities = 73/266 (27%), Positives = 114/266 (42%), Gaps = 66/266 (24%)
Query: 68 KFVNQYRIGERLGCGQFGTVYKGH--TTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYES 125
++ Y++ + LG GQ G V G TG+ VAIK + K E
Sbjct: 42 QYCGPYKLEKTLGKGQTGLVKTGTHCITGRKVAIKIVNK-------------------EK 82
Query: 126 ISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWS 185
+S VL K+ E + + HP+V+ L + ++ ++L+ GEL
Sbjct: 83 LSESVL------QKVEREIAIMKLIEHPHVLHLYDVYEN--KKYLYLLLEHVSGGEL--- 131
Query: 186 RESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPV 245
FD + + +G+L S E A K I + L + I HRDLKP+N+LLD
Sbjct: 132 ----FDYLVR-----KGRLMSKE--ARKFFRQIISALDFCHAHNICHRDLKPENLLLDE- 179
Query: 246 YHSLRISDFG-CSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHAS 304
++++++DFG SL V + L G+P + PE+ +
Sbjct: 180 RNNIKVADFGMASLQVEGSM--------------LETSCGSPHYACPEVIRGEKYDGR-- 223
Query: 305 NEQPFKIDVWSLGITVYAILYNVLPF 330
K DVWS G+ +YA+L LPF
Sbjct: 224 -----KADVWSCGVILYALLVGALPF 244
>CE25585 [T] KOG0193 Serine/threonine protein kinase RAF
Length = 813
Score = 71.2 bits (173), Expect = 3e-12
Identities = 73/290 (25%), Positives = 120/290 (41%), Gaps = 72/290 (24%)
Query: 71 NQYRIGERLGCGQFGTVYKGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISGDV 130
N++ I ++G G FGTVY+G G VAIK++ +++ T + + +V
Sbjct: 479 NEFIIQYKVGSGSFGTVYRGEFFG-TVAIKKL-----------NVVDPTPSQMAAFKNEV 526
Query: 131 LIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESKF 190
+++ K H NV+ + W RE +
Sbjct: 527 AVLK--------------KTRHLNVLLFMG-----------------------WVREPEI 549
Query: 191 DLIEQW---KSFYRG------QLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNIL 241
+I QW S YR +++ + +L +S G+ YL + IIHRDLK NI
Sbjct: 550 AIITQWCEGSSLYRHIHVQEPRVEFEMGAIIDILKQVSLGMNYLHSKNIIHRDLKTNNIF 609
Query: 242 LDPVYHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSA 301
L +++I DFG + V +K G+ Q + G+ L+ APE+ + +
Sbjct: 610 LMDDMSTVKIGDFGLA-TVKTKWTVNGGQQQ-------QQPTGSILWMAPEVIRMQDDNP 661
Query: 302 HASNEQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHR-QLKPD 350
+ DV+S GI +Y IL + LP+ D + R L+PD
Sbjct: 662 YTPQS-----DVYSFGICMYEILSSHLPYSNINNRDQILFMVGRGYLRPD 706
>At5g14720 [T] KOG0582 Ste20-like serine/threonine protein kinase
Length = 561
Score = 71.2 bits (173), Expect = 3e-12
Identities = 67/247 (27%), Positives = 100/247 (40%), Gaps = 33/247 (13%)
Query: 140 IRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESKFDLIEQWKSF 199
IR E S +NHPNV+Q + + Q+W++ P G +S +
Sbjct: 59 IRREVQTMSLINHPNVLQAHCSFTTGH--QLWVVMPYMAGGSCLHIIKSSYP-------- 108
Query: 200 YRGQLDSVEEFAVK-VLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYHSLRISDFGCSL 258
D EE + +L + L YL G IHRD+K NILLD +++++DFG S
Sbjct: 109 -----DGFEEPVIATLLRETLKALVYLHAHGHIHRDVKAGNILLDS-NGAVKLADFGVSA 162
Query: 259 IVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQPFKIDVWSLGI 318
+ F G Q + N VGTP + APE+ G FK DVWS GI
Sbjct: 163 CM-----FDTGDRQ----RSRNTFVGTPCWMAPEVMQQLHG-------YDFKADVWSFGI 206
Query: 319 TVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIYGWIHEYVVNRMLSKNTASRP 378
T + + PF + + + + +V L K+ RP
Sbjct: 207 TALELAHGHAPFSKYPPMKVLLMTLQNAPPGLDYERDKRFSKAFKEMVGTCLVKDPKKRP 266
Query: 379 TTSNILR 385
T+ +L+
Sbjct: 267 TSEKLLK 273
>Hs20545245 [D] KOG0588 Serine/threonine protein kinase
Length = 795
Score = 70.9 bits (172), Expect = 4e-12
Identities = 77/269 (28%), Positives = 120/269 (43%), Gaps = 67/269 (24%)
Query: 65 HAQKFVNQYRIGERLGCGQFGTVYKGH--TTGKVVAIKQIYKKPMNSPFSMSLIMKTMKR 122
HAQ +V YR+ + LG GQ G V G TG+ VAIK + +
Sbjct: 44 HAQ-YVGPYRLEKTLGKGQTGLVKLGVHCITGQKVAIKIVNR------------------ 84
Query: 123 YESISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGEL 182
E +S VL+ K+ E + + HP+V++L + ++ ++L+ GEL
Sbjct: 85 -EKLSESVLM------KVEREIAILKLIEHPHVLKLHDVYEN--KKYLYLVLEHVSGGEL 135
Query: 183 QWSRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILL 242
FD + + +G+L E A K I + L + I HRDLKP+N+LL
Sbjct: 136 -------FDYLVK-----KGRLTPKE--ARKFFRQIVSALDFCHSYSICHRDLKPENLLL 181
Query: 243 DPVYHSLRISDFG-CSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSA 301
D +++RI+DFG SL V L L G+P + PE+ +G
Sbjct: 182 DE-KNNIRIADFGMASLQVGDSL--------------LETSCGSPHYACPEV---IKGEK 223
Query: 302 HASNEQPFKIDVWSLGITVYAILYNVLPF 330
+ + D+WS G+ ++A+L LPF
Sbjct: 224 YDGR----RADMWSCGVILFALLVGALPF 248
>At3g27560 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 356
Score = 70.9 bits (172), Expect = 4e-12
Identities = 72/313 (23%), Positives = 135/313 (43%), Gaps = 54/313 (17%)
Query: 75 IGERLGCGQFGTVYKGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISGDVLIME 134
+G ++G G VY+G + VAIK I K SP ++ KR + ++ ++
Sbjct: 28 VGPKIGEGAHAKVYEGKYRNQTVAIKII--KRGESPEEIA------KRDNRFAREIAML- 78
Query: 135 MNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESKFDLIE 194
SK+ H N+++ + P + ++ L + G L+ +
Sbjct: 79 -------------SKVQHKNLVKFIGACKEP---MMVIVTELLLGGTLR----------K 112
Query: 195 QWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYHSLRISDF 254
S +LD AV DI+ ++ L GIIHRDLKP+N++L + +++++DF
Sbjct: 113 YLVSLRPKRLDI--RLAVGFALDIARAMECLHSHGIIHRDLKPENLILSADHKTVKLADF 170
Query: 255 GCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQPFKIDVW 314
G + ++ L ++ E GT + APEL + K+D +
Sbjct: 171 GLA---------REESLTEMMTAE----TGTYRWMAPELYSTVTLRQGEKKHYNHKVDAY 217
Query: 315 SLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIYGWIHEYVVNRMLSKNT 374
S I ++ ++ N LPF G + + L+P ++ ++ G + E +V ++
Sbjct: 218 SFAIVLWELILNKLPFEGMSNLQAAYAAAFKNLRP---SAEDLPGDL-EMIVTSCWKEDP 273
Query: 375 ASRPTTSNILRTL 387
RP + I++ L
Sbjct: 274 NERPNFTEIIQML 286
>YKL166c [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 398
Score = 70.5 bits (171), Expect = 5e-12
Identities = 71/279 (25%), Positives = 120/279 (42%), Gaps = 62/279 (22%)
Query: 70 VNQYRIGERLGCGQFGTVYKGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISGD 129
++ ++I LG G FG V+ + + N F +KT+K++
Sbjct: 85 LSDFQILRTLGTGSFGRVH-------------LIRSNHNGRF---YALKTLKKH------ 122
Query: 130 VLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESK 189
++ V E + S ++HP +I++ S Q++++ GEL
Sbjct: 123 TIVKLKQVEHTNDERRMLSIVSHPFIIRMWGTFQD--SQQVFMVMDYIEGGEL------- 173
Query: 190 FDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYHSL 249
F L+ + + F + V +F ++ L+YL + II+RDLKP+NILLD H +
Sbjct: 174 FSLLRKSQRFP----NPVAKFYA---AEVCLALEYLHSKDIIYRDLKPENILLDKNGH-I 225
Query: 250 RISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQPF 309
+I+DFG + VP + GTP + APE+ S N+
Sbjct: 226 KITDFGFAKYVPD---------------VTYTLCGTPDYIAPEVV-----STKPYNK--- 262
Query: 310 KIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLK 348
+D WS G+ +Y +L PF+ TY I + +LK
Sbjct: 263 SVDWWSFGVLIYEMLAGYTPFYNSNTMKTYENILNAELK 301
>YBR028c [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 525
Score = 70.5 bits (171), Expect = 5e-12
Identities = 82/328 (25%), Positives = 142/328 (43%), Gaps = 52/328 (15%)
Query: 63 EEHAQKFVNQYRIGERLGCGQFGTVY--KGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTM 120
E + ++ ++ LG G +G V K T K+ A+KQ+ K + +S
Sbjct: 118 ENELSRNLHDFKPVRVLGQGAYGKVLLVKDVNTSKLYAMKQLRK----AEILISQTATDS 173
Query: 121 KRYESISGDVLI------MEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQ 174
KR + D + + + E + S++ HPN+++L + +++L+
Sbjct: 174 KREDEDKNDGNNNDNDDGLSKRLERTFAERSILSEIEHPNIVKLFYSFHD--NSKLYLLL 231
Query: 175 PLAVLGELQWSRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRD 234
GEL + + L E SFY + IS L++L +G+++RD
Sbjct: 232 QYIPGGELFYHLKEHGTLDETTVSFYAAE--------------ISCALRFLHTKGVVYRD 277
Query: 235 LKPQNILLDPVYHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELN---KIVGTPLFTAP 291
LKP+N LL+ H L ++DFG SK D + + + +N I+GTP + AP
Sbjct: 278 LKPENCLLNQRGH-LVLTDFGL-----SKKSANDSAVDEEDPENVNALYSIIGTPEYCAP 331
Query: 292 ELCNFAEGSAHASNEQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDV 351
E+ G A++ N D +SLG +Y +L P+ G N I + P +
Sbjct: 332 EI---LLGKAYSQN-----CDWYSLGCLLYDMLVGKPPYTGSNHKVIINKIQQNKQGPKI 383
Query: 352 --HNSSNIYGWIHEYVVNRMLSKNTASR 377
+ S + + ++N +L K TA R
Sbjct: 384 PFYLSEGM-----KDILNALLKKETAKR 406
>Hs14993776 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 596
Score = 70.5 bits (171), Expect = 5e-12
Identities = 68/265 (25%), Positives = 120/265 (44%), Gaps = 62/265 (23%)
Query: 77 ERLGCGQFGTVYKGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISGDVLIMEMN 136
E LG G+FG V M + L K +K+ +++++E+
Sbjct: 289 EALGGGKFGAVCTC----------------MEKATGLKLAAKVIKKQTPKDKEMVLLEIE 332
Query: 137 VSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESKFDLIEQW 196
V ++LNH N+IQL +++P+ +I L GEL F+ I
Sbjct: 333 VM---------NQLNHRNLIQLYAAIETPH--EIVLFMEYIEGGEL-------FERIVD- 373
Query: 197 KSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNIL-LDPVYHSLRISDFG 255
+ ++ ++D++ + I +G+ ++ ++H DLKP+NIL ++ H ++I DFG
Sbjct: 374 EDYHLTEVDTMV-----FVRQICDGILFMHKMRVLHLDLKPENILCVNTTGHLVKIIDFG 428
Query: 256 CSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQPFKIDVWS 315
+ R + EK L GTP F +PE+ N+ + S K D+WS
Sbjct: 429 LA------------RRYNPNEK-LKVNFGTPEFLSPEVVNYDQISD--------KTDMWS 467
Query: 316 LGITVYAILYNVLPFWGETEFDTYN 340
+G+ Y +L + PF G+ + +T N
Sbjct: 468 MGVITYMLLSGLSPFLGDDDTETLN 492
>CE28674 [T] KOG0201 Serine/threonine protein kinase
Length = 651
Score = 70.5 bits (171), Expect = 5e-12
Identities = 83/311 (26%), Positives = 128/311 (40%), Gaps = 69/311 (22%)
Query: 77 ERLGCGQFGTVYKG--HTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISGDVLIME 134
ER+G G FG VYKG + TG+VVAIK I D+ E
Sbjct: 36 ERIGRGSFGEVYKGIDNRTGRVVAIKII--------------------------DLEQAE 69
Query: 135 MNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESKFDLIE 194
+ I+ E V S+ + V + ++W+I G S DL +
Sbjct: 70 DEIEDIQQEIQVLSQCDSQYVTKYFGSFLK--GSKLWIIMEYLGGG-------SALDLTK 120
Query: 195 QWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYHSLRISDF 254
G+LD E +L +I GL+YL + IHRD+K N+L+ + ++++DF
Sbjct: 121 S------GKLD--ESHIAVILREILKGLEYLHSERKIHRDIKAANVLVSE-HGDVKVADF 171
Query: 255 GCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQPFKIDVW 314
G + G+L + +K + VG+P + APEL + +K D+W
Sbjct: 172 GVA-----------GQLTETVKKRIT-FVGSPFWMAPELIK--------QSSYDYKADIW 211
Query: 315 SLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIYGWIHEYVVNRMLSKNT 374
SLGIT + P LI + P V S E+ V L+K+
Sbjct: 212 SLGITAIELANGEPPHSDLHPMRVLFLI--PKNPPPVLQGSQWSKPFKEF-VEMCLNKDP 268
Query: 375 ASRPTTSNILR 385
+RP+ S +L+
Sbjct: 269 ENRPSASTLLK 279
>CE25046 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 348
Score = 70.5 bits (171), Expect = 5e-12
Identities = 69/305 (22%), Positives = 124/305 (40%), Gaps = 73/305 (23%)
Query: 72 QYRIGERLGCGQFGTVYKGHT---TGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISG 128
+Y + LG G F V+ + G++ A+K I KK + + ES+
Sbjct: 21 KYDFRDVLGTGAFSKVFLAESKSDAGQMYAVKCIDKKALKG------------KEESLEN 68
Query: 129 DVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRES 188
++ ++ KL H N++QL + D ++L+ L GEL
Sbjct: 69 EIKVLR--------------KLRHNNIVQLFDTYDE--KQFVYLVMELVTGGEL------ 106
Query: 189 KFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILL--DPVY 246
FD I S+ E+ A ++ + + ++ G++HRDLKP+N+L
Sbjct: 107 -FDRIVAKGSY-------TEQDASNLIRQVLEAVGFMHDNGVVHRDLKPENLLYYNQDED 158
Query: 247 HSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNE 306
+ ISDFG S S + + GTP + APE+ +
Sbjct: 159 SKIMISDFGLSKTEDSGV--------------MATACGTPGYVAPEVL----------QQ 194
Query: 307 QPF--KIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIYGWIHEY 364
+P+ +DVWS+G+ Y +L PF+ E++ + + I + + D I ++
Sbjct: 195 KPYGKAVDVWSIGVIAYILLCGYPPFYDESDANLFAQIIKGEYEFDAPYWDQISDSAKDF 254
Query: 365 VVNRM 369
+ + M
Sbjct: 255 ITHLM 259
>CE07510 [T] KOG0201 Serine/threonine protein kinase
Length = 653
Score = 70.5 bits (171), Expect = 5e-12
Identities = 83/311 (26%), Positives = 128/311 (40%), Gaps = 69/311 (22%)
Query: 77 ERLGCGQFGTVYKG--HTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISGDVLIME 134
ER+G G FG VYKG + TG+VVAIK I D+ E
Sbjct: 38 ERIGRGSFGEVYKGIDNRTGRVVAIKII--------------------------DLEQAE 71
Query: 135 MNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESKFDLIE 194
+ I+ E V S+ + V + ++W+I G S DL +
Sbjct: 72 DEIEDIQQEIQVLSQCDSQYVTKYFGSFLK--GSKLWIIMEYLGGG-------SALDLTK 122
Query: 195 QWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYHSLRISDF 254
G+LD E +L +I GL+YL + IHRD+K N+L+ + ++++DF
Sbjct: 123 S------GKLD--ESHIAVILREILKGLEYLHSERKIHRDIKAANVLVSE-HGDVKVADF 173
Query: 255 GCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQPFKIDVW 314
G + G+L + +K + VG+P + APEL + +K D+W
Sbjct: 174 GVA-----------GQLTETVKKRIT-FVGSPFWMAPELIK--------QSSYDYKADIW 213
Query: 315 SLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIYGWIHEYVVNRMLSKNT 374
SLGIT + P LI + P V S E+ V L+K+
Sbjct: 214 SLGITAIELANGEPPHSDLHPMRVLFLI--PKNPPPVLQGSQWSKPFKEF-VEMCLNKDP 270
Query: 375 ASRPTTSNILR 385
+RP+ S +L+
Sbjct: 271 ENRPSASTLLK 281
>At2g46700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 595
Score = 70.5 bits (171), Expect = 5e-12
Identities = 65/285 (22%), Positives = 115/285 (39%), Gaps = 67/285 (23%)
Query: 65 HAQKFVNQYRIGERLGCGQFGTVY-----KGHTTGKVVAIKQIYKKPMNSPFSMSLIMKT 119
+ + F +Y +G+ +G G FG KG +A+K I K M + ++ + +
Sbjct: 135 YGKNFGAKYELGKEVGRGHFGHTCSGRGKKGDIKDHPIAVKIISKAKMTTAIAIEDVRRE 194
Query: 120 MKRYESISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVL 179
+K +S+SG H +I+ + + ++ ++++ L
Sbjct: 195 VKLLKSLSG-----------------------HKYLIKYYDACED--ANNVYIVMELCDG 229
Query: 180 GELQWSRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQN 239
GEL D I Y D + V++L +S + QG++HRDLKP+N
Sbjct: 230 GEL-------LDRILARGGKYPE--DDAKAIVVQILTVVS----FCHLQGVVHRDLKPEN 276
Query: 240 ILLDPVYHS--LRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFA 297
L L++ DFG S + ++ LN IVG+ + APE+ +
Sbjct: 277 FLFTSSREDSDLKLIDFGLSDFIRP-------------DERLNDIVGSAYYVAPEVLH-- 321
Query: 298 EGSAHASNEQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLI 342
+ D+WS+G+ Y +L PFW TE + +
Sbjct: 322 -------RSYSLEADIWSIGVITYILLCGSRPFWARTESGIFRTV 359
>SPBC8D2.19 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 559
Score = 70.1 bits (170), Expect = 7e-12
Identities = 76/305 (24%), Positives = 130/305 (41%), Gaps = 71/305 (23%)
Query: 69 FVNQYRIGERLGCGQFGTVYKGHTTGK-----VVAIKQIYKKPMNSPFSMSLIMKTMKRY 123
F ++Y + ++LG G FGTVY K VA+K++ P L ++
Sbjct: 17 FEDRYLVKQKLGDGSFGTVYLAQRKEKNGLYETVAVKKLKNSSKPKPKHELLKLRESLAL 76
Query: 124 ESISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQ 183
IS HP +I LLE PY + I+L+ ++
Sbjct: 77 RKIS-----------------------KHPCLIDLLETFMDPYRN-IFLV--------ME 104
Query: 184 WSRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLD 243
+ + F L ++ +G+L + +E A +L I +G++++ G +HRD+KP+NIL+
Sbjct: 105 FMDCNLFQLFKR----RQGRLFT-KETAFNILLQIISGIEHIHKHGFMHRDIKPENILVK 159
Query: 244 PV-------YHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNF 296
+ +S+++ DFG + S P L + V T + APEL
Sbjct: 160 RISPKPISSRYSIKLGDFGLARPSVSSDP-------------LTEYVSTRWYRAPELL-L 205
Query: 297 AEGSAHASNEQPFKIDVWSLGITVYAILYNVLP-FWGETEFDTYNLICHRQLKPDVHNSS 355
GS + S +D+++ G V+ I Y++ P F G E D N +C P +
Sbjct: 206 RSGSYNHS------VDLYAFGCIVFEI-YSLKPLFPGRNETDQLNRVCEILGNPGIDELD 258
Query: 356 NIYGW 360
++ W
Sbjct: 259 TLHYW 263
>Hs7705551 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 632
Score = 70.1 bits (170), Expect = 7e-12
Identities = 72/279 (25%), Positives = 127/279 (44%), Gaps = 71/279 (25%)
Query: 70 VNQYRIGERLGCGQFGTVYKGHT--TGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESIS 127
+N+Y +LG G +G+V G + +G+++AIK++ +K S
Sbjct: 1 MNRYTTIRQLGDGTYGSVLLGRSIESGELIAIKKMKRK-------------------FYS 41
Query: 128 GDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRE 187
+ + + V ++ KLNH NV++L E + +D ++ I ++ +E
Sbjct: 42 WEECMNQREVKSLK-------KLNHANVVKLKEVIRE--NDHLYFI--------FEYMKE 84
Query: 188 SKFDLIEQWKSFYRGQLDSVEEFAVK-VLGDISNGLQYLQGQGIIHRDLKPQNIL-LDPV 245
+ + LI++ + E A++ ++ I GL ++ G HRDLKP+N+L + P
Sbjct: 85 NLYQLIKERNKLF-------PESAIRNIMYQILQGLAFIHKLGFFHRDLKPENLLCMGP- 136
Query: 246 YHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASN 305
++I+DFG + + SK P+ D V T + APE+ S
Sbjct: 137 -ELVKIADFGLAREIRSKPPYTD-------------YVSTRWYRAPEV-------LLRST 175
Query: 306 EQPFKIDVWSLGITVYAILYNVLP-FWGETEFDTYNLIC 343
IDVW++G + A +Y + P F G +E DT IC
Sbjct: 176 NYSSPIDVWAVG-CIMAEVYTLRPLFPGASEIDTIFKIC 213
>Hs4506075 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD and related
proteins
Length = 912
Score = 70.1 bits (170), Expect = 7e-12
Identities = 69/259 (26%), Positives = 113/259 (42%), Gaps = 67/259 (25%)
Query: 77 ERLGCGQFGTVYKG--HTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISGDVLIME 134
E LG GQFG VY G TG+ VAIK I K + P
Sbjct: 587 EVLGSGQFGIVYGGKHRKTGRDVAIKIIDK--LRFPTKQE-------------------- 624
Query: 135 MNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESKFDLIE 194
S++R E + L+HP V+ L ++P ++++++ + D++E
Sbjct: 625 ---SQLRNEVAILQNLHHPGVVNLECMFETP--ERVFVVM-----------EKLHGDMLE 668
Query: 195 QWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILL---DPVYHSLRI 251
S +G+L E ++ I L++L + I+H DLKP+N+LL DP + +++
Sbjct: 669 MILSSEKGRLP--EHITKFLITQILVALRHLHFKNIVHCDLKPENVLLASADP-FPQVKL 725
Query: 252 SDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQPFKI 311
DFG + I+ K F+ +VGTP + APE+ + +
Sbjct: 726 CDFGFARIIGEK-SFR------------RSVVGTPAYLAPEVLR--------NKGYNRSL 764
Query: 312 DVWSLGITVYAILYNVLPF 330
D+WS+G+ +Y L PF
Sbjct: 765 DMWSVGVIIYVSLSGTFPF 783
>CE03584 [T] KOG0607 MAP kinase-interacting kinase and related
serine/threonine protein kinases
Length = 761
Score = 70.1 bits (170), Expect = 7e-12
Identities = 78/270 (28%), Positives = 119/270 (43%), Gaps = 52/270 (19%)
Query: 69 FVNQYRI-GERLGCGQFGTVY--KGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYES 125
F + Y++ E LG G +G+V K +G A+K + K+ E+
Sbjct: 196 FFDYYKLTDEHLGSGAYGSVTTCKSIKSGVEYAVKIVDKQG-----------------ET 238
Query: 126 ISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWS 185
S ++ E+N+ F T K +HPN++QLL+ + +L+ G L
Sbjct: 239 HSRKRILREVNI-------FKTCK-DHPNIVQLLDWFED--ETNFYLVMEKMRGGPL--- 285
Query: 186 RESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPV 245
I Q K F EE A +V DIS L+++ +GI HRD+KP+N+L
Sbjct: 286 ----LQHILQRKYF-------TEEEARRVTKDISLALKFMHDRGIAHRDVKPENVLCTDP 334
Query: 246 YHSLRISDFGCSLIVPSKLPFKDGR---LQDLFEKELNKIVGTPLFTAPELCNFAEGSAH 302
H + C L + S+ P + R Q E +L VG+ F APE+ + G
Sbjct: 335 NHVSPVK--LCDLDLASQRPPQHERHPLSQVASEPDLASPVGSAEFMAPEVVDAYVGD-- 390
Query: 303 ASNEQPFKIDVWSLGITVYAILYNVLPFWG 332
S + K D WSLG+ +Y +L PF G
Sbjct: 391 -SLKYDKKCDTWSLGVILYIMLAGYAPFQG 419
>At5g40540 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 353
Score = 70.1 bits (170), Expect = 7e-12
Identities = 69/313 (22%), Positives = 127/313 (40%), Gaps = 54/313 (17%)
Query: 75 IGERLGCGQFGTVYKGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISGDVLIME 134
+G ++G G +Y+G K VAIK I+K + E I+
Sbjct: 28 VGPKIGEGAHAKIYEGKYKNKTVAIK---------------IVKRGESPEEIA------- 65
Query: 135 MNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESKFDLIE 194
S+ E + S++ H N+++ + P + ++ EL + L+
Sbjct: 66 KRESRFAREVSMLSRVQHKNLVKFIGACKEPI---------MVIVTELLLGGTLRKYLV- 115
Query: 195 QWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYHSLRISDF 254
S G LD AV DI+ ++ L G+IHRDLKP++++L Y +++++DF
Sbjct: 116 ---SLRPGSLDI--RVAVGYALDIARAMECLHSHGVIHRDLKPESLILTADYKTVKLADF 170
Query: 255 GCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQPFKIDVW 314
G + ++ L ++ E GT + APEL + K+D +
Sbjct: 171 GLA---------REESLTEMMTAE----TGTYRWMAPELYSTVTLRHGEKKHYNHKVDAY 217
Query: 315 SLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIYGWIHEYVVNRMLSKNT 374
S I ++ +++N LPF G + + ++P + I V ++
Sbjct: 218 SFAIVLWELIHNKLPFEGMSNLQAAYAAAFKNVRPSADDLPKDLAMI----VTSCWKEDP 273
Query: 375 ASRPTTSNILRTL 387
RP + I++ L
Sbjct: 274 NDRPNFTEIIQML 286
>7302570 [R] KOG0586 Serine/threonine protein kinase
Length = 702
Score = 70.1 bits (170), Expect = 7e-12
Identities = 70/267 (26%), Positives = 115/267 (42%), Gaps = 64/267 (23%)
Query: 70 VNQYRIGERLGCGQFGTVYKGHT--TGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESIS 127
V Y + + +G G F V T VAIK I K +N + + KT +
Sbjct: 38 VGYYELEKTIGKGNFAVVKLATNIVTKTKVAIKIIDKTCLNEEY----LNKTFR------ 87
Query: 128 GDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRE 187
E + L HP++ +L E ++S I+L+ A GE+
Sbjct: 88 ---------------EIAILKSLRHPHITRLYEVMES--QSMIYLVTEYAPNGEI----- 125
Query: 188 SKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYH 247
FD + G++ E A +V + + + Y +G++HRDLK +N+LLD
Sbjct: 126 --FDHLVA-----NGRMKEPE--AARVFTQLVSAVHYCHRRGVVHRDLKAENVLLDKDM- 175
Query: 248 SLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQ 307
+++++DFG S +++G L G+P + APE+ E
Sbjct: 176 NIKLADFGFS------NHYEEG-------ATLKTWCGSPPYAAPEVFQGLEYDGP----- 217
Query: 308 PFKIDVWSLGITVYAILYNVLPFWGET 334
K D+WSLG+ +YA++ LPF G+T
Sbjct: 218 --KSDIWSLGVVLYALVCGALPFDGKT 242
>7295638 [T] KOG0603 Ribosomal protein S6 kinase
Length = 911
Score = 70.1 bits (170), Expect = 7e-12
Identities = 71/286 (24%), Positives = 118/286 (40%), Gaps = 58/286 (20%)
Query: 62 QEEHAQKFVNQYRIGERLGCGQFGTVYKGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMK 121
+E H + +Q+ + LG G FG KV +++I K + ++M ++ K
Sbjct: 188 KEGHDKADPSQFELLRVLGEGSFG---------KVFLVRKIIGKDAGTLYAMKVLKKATL 238
Query: 122 RYESISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGE 181
+ + + N KI + + H +++L +P +++LI G+
Sbjct: 239 KVKD-----RVRSTNERKI------LADVGHAFIVRLHYAFQTP--GKLYLILDFLRGGD 285
Query: 182 LQWSRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNIL 241
L + E+ FY L +++ + +L GII+RDLKP+NIL
Sbjct: 286 LFTRLSKEVMFTEEDVKFY--------------LAELALAMNHLHTLGIIYRDLKPENIL 331
Query: 242 LDPVYHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSA 301
LD H + ++DFG S Q L + GT + APE+ N
Sbjct: 332 LDEHGH-IALTDFGLS-------------KQPLDGSKTYSFCGTVEYMAPEIVN------ 371
Query: 302 HASNEQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQL 347
F D WS G+ +Y +L LPF G+T +T N I +L
Sbjct: 372 --RKGHDFAADWWSFGVLMYEMLTGNLPFHGQTRQETMNQILRSKL 415
Score = 60.1 bits (144), Expect = 7e-09
Identities = 70/241 (29%), Positives = 107/241 (44%), Gaps = 45/241 (18%)
Query: 151 NHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESKFDLIEQWKSFYRGQLDSVEEF 210
NHPN++ L + S +L+ L GEL D I GQ+ E
Sbjct: 627 NHPNIVTLYSVYEDAGS--AYLVMELLKGGEL-------LDRI-----LAVGQM--CESE 670
Query: 211 AVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYHSLRISDFGCSLIVPSKLPFKDGR 270
A VL I++ + YL G++HRDLKP N+ +Y S+R + P L +
Sbjct: 671 ASAVLRTIASAVAYLHEHGVVHRDLKPSNM----IYASMRQT--------PETL-----K 713
Query: 271 LQDL-FEKEL---NKIVGTPLFTAPELCNFAEGSAHASNEQPFKIDVWSLGITVYAILYN 326
L DL F K+L N ++ TP +TA NF D+WSLG+ +Y +L
Sbjct: 714 LCDLGFAKQLRADNGLLMTPCYTA----NFVAPEVLKRQGYDLACDIWSLGVLLYIMLSG 769
Query: 327 VLPFWGETEFDTYNLICHRQLKPDVHNSSNIYGWIH---EYVVNRMLSKNTASRPTTSNI 383
PF T D+ ++I R + +S+ + I + ++ +ML +RPT + I
Sbjct: 770 RTPF-ASTPNDSPDVILKRIGSGQIDFTSSRWALISVPAKELLRQMLHIVPENRPTAARI 828
Query: 384 L 384
L
Sbjct: 829 L 829
>7290147 [T] KOG0583 Serine/threonine protein kinase
Length = 291
Score = 70.1 bits (170), Expect = 7e-12
Identities = 54/192 (28%), Positives = 94/192 (48%), Gaps = 35/192 (18%)
Query: 140 IRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESKFDLIEQWKSF 199
I+ E ++ S+L HP++++ L ++ + ++ G L+ D+I+Q S
Sbjct: 55 IKEEVYIISQLRHPHIVEFLRSFS--HAGTVNIVMEYVPNGTLR-------DVIQQLPS- 104
Query: 200 YRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYHSLRISDFGCSLI 259
G +E + D+ GL+YL + +IHRD+KP+N+LLD ++I+DFG + +
Sbjct: 105 --GTGGVNQERLMGYFRDMVVGLEYLHIRCVIHRDIKPENMLLD-ANDRVKIADFGIANV 161
Query: 260 -VPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQPFKIDVWSLGI 318
PS +L +GTP++ APE + + + FK DVWSLG+
Sbjct: 162 HAPS--------------TQLQAGMGTPMYMAPE-------AMSSQGKVDFKSDVWSLGL 200
Query: 319 TVYAILYNVLPF 330
+Y + PF
Sbjct: 201 VLYELCLGRSPF 212
>YOL045w [T] KOG1152 Signal transduction serine/threonine kinase with PAS/PAC
sensor domain
Length = 1101
Score = 69.7 bits (169), Expect = 9e-12
Identities = 70/267 (26%), Positives = 116/267 (43%), Gaps = 55/267 (20%)
Query: 124 ESISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQ 183
E I D + + + I E + + LN + +L+ LD D + I+ V GE
Sbjct: 875 ERILVDTWVRDRKLGTIPSEIQIMATLNKNSQENILKLLDFFEDDDYYYIET-PVHGET- 932
Query: 184 WSRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLD 243
FD+IE K D VE A V + +++L QGI+HRD+K +N+++D
Sbjct: 933 -GSIDLFDVIEFKK-------DMVEHEAKLVFKQVVASIKHLHDQGIVHRDIKDENVIVD 984
Query: 244 PVYHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHA 303
+ +++ DFG + + S PF D+F VGT + APE+ GS++
Sbjct: 985 S-HGFVKLIDFGSAAYIKSG-PF------DVF-------VGTMDYAAPEVLG---GSSYK 1026
Query: 304 SNEQPFKIDVWSLGITVYAILYNVLPFW-------GETEFDTYNLICHRQLKPDVHNSSN 356
Q D+W+LG+ +Y I+Y P++ GE FD + +
Sbjct: 1027 GKPQ----DIWALGVLLYTIIYKENPYYNIDEILEGELRFDKSEHVSEECIS-------- 1074
Query: 357 IYGWIHEYVVNRMLSKNTASRPTTSNI 383
++ R+L++ RPT I
Sbjct: 1075 --------LIKRILTREVDKRPTIDEI 1093
>YDL101c [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 513
Score = 69.7 bits (169), Expect = 9e-12
Identities = 74/282 (26%), Positives = 112/282 (39%), Gaps = 76/282 (26%)
Query: 69 FVNQYRIGERLGCGQFGTVY--KGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESI 126
F ++Y +G+ LG G + V K TG+ VA+K I+ N K K++
Sbjct: 196 FFDKYLLGKELGAGHYALVKEAKNKKTGQQVAVK-IFHAQQNDD------QKKNKQF--- 245
Query: 127 SGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSR 186
R E + ++ HPN++ LL+ P S IQ VL
Sbjct: 246 --------------REETNILMRVQHPNIVNLLDSFVEPISKS--QIQKYLVL------- 282
Query: 187 ESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILL---- 242
K D E ++ R +E + + + GL+YL Q IIHRD+KP+NILL
Sbjct: 283 -EKIDDGELFERIVRKTCLRQDE-SKALFKQLLTGLKYLHEQNIIHRDIKPENILLNITR 340
Query: 243 --------------DPVYHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLF 288
D + ++I+DFG + G +Q N + GTP +
Sbjct: 341 RENPSQVQLGPWDEDEIDIQVKIADFGLAKFT--------GEMQ-----FTNTLCGTPSY 387
Query: 289 TAPELCNFAEGSAHASNEQPFKIDVWSLGITVYAILYNVLPF 330
APE+ K+D+WS G+ +Y L PF
Sbjct: 388 VAPEVL--------TKKGYTSKVDLWSAGVILYVCLCGFPPF 421
>Hs7382496 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 545
Score = 69.7 bits (169), Expect = 9e-12
Identities = 77/317 (24%), Positives = 133/317 (41%), Gaps = 71/317 (22%)
Query: 72 QYRIGERLGCGQFGTVYKGH--TTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISGD 129
+Y E++G G GTVY TG+ VAIKQ MN ++ + E I +
Sbjct: 269 KYTRFEKIGQGASGTVYTAMDVATGQEVAIKQ-----MN--------LQQQPKKELIINE 315
Query: 130 VLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESK 189
+L+M N +PN++ L+ D++W++ G L
Sbjct: 316 ILVMREN--------------KNPNIVNYLDSY--LVGDELWVVMEYLAGGSLT------ 353
Query: 190 FDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYHSL 249
D++ + GQ+ +V + L++L +IHRD+K NILL + S+
Sbjct: 354 -DVVTE-TCMDEGQIAAV-------CRECLQALEFLHSNQVIHRDIKSDNILLG-MDGSV 403
Query: 250 RISDFG-CSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQP 308
+++DFG C+ I P + + + +VGTP + APE+ A+
Sbjct: 404 KLTDFGFCAQITPE-------------QSKRSTMVGTPYWMAPEV---VTRKAYGP---- 443
Query: 309 FKIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIYGWIHEYVVNR 368
K+D+WSLGI ++ P+ E LI P++ N + ++ +NR
Sbjct: 444 -KVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNG-TPELQNPEKLSAIFRDF-LNR 500
Query: 369 MLSKNTASRPTTSNILR 385
L + R + +L+
Sbjct: 501 CLDMDVEKRGSAKELLQ 517
>Hs10334852 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 623
Score = 69.7 bits (169), Expect = 9e-12
Identities = 44/136 (32%), Positives = 68/136 (49%), Gaps = 13/136 (9%)
Query: 209 EFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYHSLRISDFGCSLIVPSKLPFKD 268
E A L +I + + G +HRD+KP NILLD H +R++DFG L + + D
Sbjct: 170 EMARFYLAEIVMAIDSVHRLGYVHRDIKPDNILLDRCGH-IRLADFGSCLKLRA-----D 223
Query: 269 GRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQPFKIDVWSLGITVYAILYNVL 328
G ++ L VGTP + +PE+ G + P + D W+LG+ Y + Y
Sbjct: 224 GTVRSLVA------VGTPDYLSPEILQAVGGGPGTGSYGP-ECDWWALGVFAYEMFYGQT 276
Query: 329 PFWGETEFDTYNLICH 344
PF+ ++ +TY I H
Sbjct: 277 PFYADSTAETYGKIVH 292
>CE28479 [T] KOG0583 Serine/threonine protein kinase
Length = 822
Score = 69.7 bits (169), Expect = 9e-12
Identities = 79/319 (24%), Positives = 131/319 (40%), Gaps = 71/319 (22%)
Query: 70 VNQYRIGERLGCGQFGTVYKGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISGD 129
+ Y +G +G G F TV + I KT +SI
Sbjct: 13 IGLYDVGRAIGKGNFATVR----------------------IARHKIAKTKVAIKSIDVS 50
Query: 130 VLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESK 189
L E N+ K+ E + ++HP++++ E + + ++++ GEL +
Sbjct: 51 ALDRE-NLIKLEREVKIVKVIDHPHIVKSYEIMR--VDNMLYIVSEYCSSGELYET---- 103
Query: 190 FDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYHSL 249
LIE+ + E A K + ++ + YL QGI+HRDLK +NILL ++
Sbjct: 104 --LIEKGRV--------AENVARKWFSETASAVAYLHSQGIVHRDLKAENILLGK-NSNI 152
Query: 250 RISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQPF 309
+I DFG S F+ G ++ LN G+P + APEL ++
Sbjct: 153 KIIDFGFS-------NFQTG------DQLLNTWCGSPPYAAPEL-------LLGNSYDGM 192
Query: 310 KIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIYGWIH---EYVV 366
K D+WS+G+ +Y ++ PF D+ N + L V I W+ +
Sbjct: 193 KADIWSMGVLLYILVAGGFPF----PSDSVNKLKRSVLSGLV----KIPYWVSVECADFI 244
Query: 367 NRMLSKNTASRPTTSNILR 385
+ML N R T N+L+
Sbjct: 245 RKMLVLNPGKRYTIQNVLQ 263
>CE11916 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1548
Score = 69.7 bits (169), Expect = 9e-12
Identities = 46/139 (33%), Positives = 66/139 (47%), Gaps = 15/139 (10%)
Query: 208 EEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYHSLRISDFGCSLIVPSKLPFK 267
E A + ++ + L G +HRD+KP N+LLD H +R++DFG L +
Sbjct: 181 ESMAKFYIAEMVLAIDSLHRLGYVHRDVKPDNVLLDMQGH-IRLADFGSCLRI-----LA 234
Query: 268 DGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQPFKIDVWSLGITVYAILYNV 327
DG + N VGTP + +PE+ E ++ D WSLGI +Y +LY
Sbjct: 235 DGSVAS------NVAVGTPDYISPEILRAMEDGRGRYGKE---CDWWSLGICMYEMLYGT 285
Query: 328 LPFWGETEFDTYNLICHRQ 346
PF+ E DTY I Q
Sbjct: 286 TPFYSERLVDTYGKIMSHQ 304
>At1g67890 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 738
Score = 69.7 bits (169), Expect = 9e-12
Identities = 71/258 (27%), Positives = 115/258 (44%), Gaps = 64/258 (24%)
Query: 75 IGERLGCGQFGTVYKGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISGDVLIME 134
IGE++G G GTVY G G VA+K K+ + E
Sbjct: 489 IGEQIGQGSCGTVYHGLWFGSDVAVKVFSKQEYS-------------------------E 523
Query: 135 MNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESKFDLIE 194
++ + E + +L HPNV+ + + SP Q L ++ E R S F L++
Sbjct: 524 EIITSFKQEVSLMKRLRHPNVLLFMGAVASP--------QRLCIVTEF-LPRGSLFRLLQ 574
Query: 195 QWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQ--GQGIIHRDLKPQNILLDPVYHSLRIS 252
+ KS +LD + + DI+ G+ YL IIHRDLK N+L+D + +++++
Sbjct: 575 RNKS----KLDLRRR--IHMASDIARGMNYLHHCSPPIIHRDLKSSNLLVDRNW-TVKVA 627
Query: 253 DFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQPFKID 312
DFG S I +GR GTP + APE+ A++E K D
Sbjct: 628 DFGLSRIKHETYLTTNGR-------------GTPQWMAPEVLR-----NEAADE---KSD 666
Query: 313 VWSLGITVYAILYNVLPF 330
V+S G+ ++ ++ +P+
Sbjct: 667 VYSFGVVLWELVTEKIPW 684
>7297080 [T] KOG0583 Serine/threonine protein kinase
Length = 329
Score = 69.7 bits (169), Expect = 9e-12
Identities = 66/261 (25%), Positives = 120/261 (45%), Gaps = 60/261 (22%)
Query: 75 IGERLGCGQFGTVYKGHTT--GKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISGDVLI 132
+G+ +G G + V G + GK VA+K I K S ++ + + + E++ G
Sbjct: 70 LGKVIGTGNYAKVKIGFSEEYGKRVAVKIISKVKAPSEYTQKFLPREI---EAVKG---- 122
Query: 133 MEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGEL-QWSRESKFD 191
L+H N+I + +++ S +++LI LA G L + RE KF
Sbjct: 123 -----------------LHHENLITFYQSIET--SHRVYLIMQLAENGTLLDYVRERKFL 163
Query: 192 LIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYHSLRI 251
Q ++ ++ + +VE Y+ +G++HRD+K +N+LLD + +L++
Sbjct: 164 DEPQSRTLFKQLVSAVE---------------YIHSKGVVHRDIKCENLLLDENW-NLKL 207
Query: 252 SDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQPFKI 311
DFG + KD R D G+ + +PE+ +G A+ PF
Sbjct: 208 IDFGFAR--------KDTRTSDNQVILSKTFCGSYAYASPEI---LKGVAY----DPFMS 252
Query: 312 DVWSLGITVYAILYNVLPFWG 332
D+W+ G+ YA+++ LP+ G
Sbjct: 253 DIWACGVVCYAMVFGRLPYDG 273
>YAR019c [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 974
Score = 69.3 bits (168), Expect = 1e-11
Identities = 77/316 (24%), Positives = 129/316 (40%), Gaps = 73/316 (23%)
Query: 72 QYRIGERLGCGQFGTVYKGHT--TGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISGD 129
QY + + +G G +G VYK T +VVAIK++ YE+
Sbjct: 24 QYHLKQVIGRGSYGVVYKAINKHTDQVVAIKEVV-------------------YEN---- 60
Query: 130 VLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESK 189
+ ++ I E + LNH N+++ + Y +++++ G L+
Sbjct: 61 ----DEELNDIMAEISLLKNLNHNNIVKYHGFIRKSY--ELYILLEYCANGSLR------ 108
Query: 190 FDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYHSL 249
+ R E + + GL+YL G+G+IHRD+K NILL +++
Sbjct: 109 -------RLISRSSTGLSENESKTYVTQTLLGLKYLHGEGVIHRDIKAANILLS-ADNTV 160
Query: 250 RISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQPF 309
+++DFG S IV S + GT + APE+ G+ AS
Sbjct: 161 KLADFGVSTIVNS---------------SALTLAGTLNWMAPEIL----GNRGASTLS-- 199
Query: 310 KIDVWSLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIYGWIHEYVVNRM 369
D+WSLG TV +L P+ T+ + Y + + P S + ++ + V
Sbjct: 200 --DIWSLGATVVEMLTKNPPYHNLTDANIYYAVENDTYYPPSSFSEPLKDFLSKCFV--- 254
Query: 370 LSKNTASRPTTSNILR 385
KN RPT +L+
Sbjct: 255 --KNMYKRPTADQLLK 268
>Hs4506737 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 525
Score = 69.3 bits (168), Expect = 1e-11
Identities = 80/306 (26%), Positives = 128/306 (41%), Gaps = 74/306 (24%)
Query: 79 LGCGQFGTVYK-----GHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISGDVLIM 133
LG G +G V++ G TGK+ A+K + K ++I++ K + I+
Sbjct: 97 LGKGGYGKVFQVRKVTGANTGKIFAMKVLKK---------AMIVRNAKDTAHTKAERNIL 147
Query: 134 EMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESKFDLI 193
E ++ HP ++ L+ + +++LI GEL E + +
Sbjct: 148 E--------------EVKHPFIVDLIYAFQT--GGKLYLILEYLSGGELFMQLEREGIFM 191
Query: 194 EQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYHSLRISD 253
E FY L +IS L +L +GII+RDLKP+NI+L+ H ++++D
Sbjct: 192 EDTACFY--------------LAEISMALGHLHQKGIIYRDLKPENIMLNHQGH-VKLTD 236
Query: 254 FGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQPFKIDV 313
FG K DG + F GT + APE+ G A +D
Sbjct: 237 FGL-----CKESIHDGTVTHTF-------CGTIEYMAPEIL-MRSGHNRA-------VDW 276
Query: 314 WSLGITVYAILYNVLPFWGETEFDTYNLI--CHRQLKPDVHNSSNIYGWIHEYVVNRMLS 371
WSLG +Y +L PF GE T + I C L P + + ++ ++L
Sbjct: 277 WSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPPYLTQEA-------RDLLKKLLK 329
Query: 372 KNTASR 377
+N ASR
Sbjct: 330 RNAASR 335
>Hs22057171 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 456
Score = 69.3 bits (168), Expect = 1e-11
Identities = 80/311 (25%), Positives = 137/311 (43%), Gaps = 71/311 (22%)
Query: 80 GCGQFGTVYKGH--TTGKVVAIKQIYKKPMNSPFSMSLIMKT--MKRYESISGDVLIMEM 135
G G+FG V+K TG +A K I+KT MK E + ++ +M
Sbjct: 181 GRGRFGQVHKCEETATGLKLAAK---------------IIKTRGMKDKEEVKNEISVM-- 223
Query: 136 NVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESKFDLIEQ 195
++L+H N+IQL + +S + I L+ GEL FD I
Sbjct: 224 ------------NQLDHANLIQLYDAFES--KNDIVLVMEYVDGGEL-------FDRIID 262
Query: 196 WKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNIL-LDPVYHSLRISDF 254
+S+ +LD++ + I G++++ I+H DLKP+NIL ++ ++I DF
Sbjct: 263 -ESYNLTELDTI-----LFMKQICEGIRHMHQMYILHLDLKPENILCVNRDAKQIKIIDF 316
Query: 255 GCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQPFKIDVW 314
G + + ++L GTP F APE+ N+ S F D+W
Sbjct: 317 GLARRYKPR-------------EKLKVNFGTPEFLAPEVVNYDFVS--------FPTDMW 355
Query: 315 SLGITVYAILYNVLPFWGETEFDTYNLICHRQLKPDVHNSSNIYGWIHEYVVNRMLSKNT 374
S+G+ Y +L + PF G+ + +T N I + + +I E+ ++++L K
Sbjct: 356 SVGVIAYMLLSGLSPFLGDNDAETLNNILACRWDLEDEEFQDISEEAKEF-ISKLLIKEK 414
Query: 375 ASRPTTSNILR 385
+ R + S L+
Sbjct: 415 SWRISASEALK 425
>ECU03g0980 [T] KOG0583 Serine/threonine protein kinase
Length = 566
Score = 69.3 bits (168), Expect = 1e-11
Identities = 75/266 (28%), Positives = 115/266 (43%), Gaps = 59/266 (22%)
Query: 68 KFVNQYRIGERLGCGQFGTVYKGHT--TGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYES 125
K++ YR ++LG G V G +G+ VAIK I ++
Sbjct: 53 KWIGSYRFVKQLGTGSSSKVVLGRDVRSGEKVAIKIIPRRVNGGE--------------- 97
Query: 126 ISGDVLIMEMNVS-KIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQW 184
+GD MEM ++ E ++S LNHP++ +L L SP +LI +L
Sbjct: 98 -TGD---MEMRCDQRVFREVIISSVLNHPHIARLKNFLYSP--THYFLIFEYVKGRQL-- 149
Query: 185 SRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDP 244
+D+I G L E + + + + Y+ ++HRDLK +NIL+D
Sbjct: 150 -----YDII-----ISSGPLKEKE--GQRYFRQLLSAIDYIHRNSVVHRDLKIENILIDE 197
Query: 245 VYHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHAS 304
++++ DFG S +K LN G+ F APEL +G +
Sbjct: 198 -NDNVKLIDFGLSNFYDNKTL-------------LNTFCGSLYFAAPELL---QGQRYCG 240
Query: 305 NEQPFKIDVWSLGITVYAILYNVLPF 330
E IDVWSLG+ +YAIL +PF
Sbjct: 241 PE----IDVWSLGVVLYAILCGCVPF 262
>YDR490c [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 766
Score = 68.9 bits (167), Expect = 1e-11
Identities = 72/278 (25%), Positives = 126/278 (44%), Gaps = 55/278 (19%)
Query: 70 VNQYRIGERLGCGQFGTVY--KGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESIS 127
+ ++ GE+LG G + +V +GK A+K + K+ LI + +Y ++
Sbjct: 122 IKDFKFGEQLGDGSYSSVVLATARDSGKKYAVKVLSKE--------YLIRQKKVKYVTVE 173
Query: 128 GDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRE 187
+ + ++N +K ++ F T + + ++ LLE +P+ D + LI+ L E
Sbjct: 174 -KLALQKLNGTKGIFKLFFTFQ-DEASLYFLLEY--APHGDFLGLIKKYGSLNET----- 224
Query: 188 SKFDLIEQWKSFYRGQL-DSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVY 246
+Y Q+ D+V+ L GIIHRD+KP+NILLD
Sbjct: 225 --------CARYYASQIIDAVDS---------------LHNIGIIHRDIKPENILLDK-N 260
Query: 247 HSLRISDFGCSLIVPSK-LPFKDGR-LQDLFEKELNKIVGTPLFTAPELCNFAEGSAHAS 304
++++DFG + I+P + DG+ DL+ K VGT + +PEL N
Sbjct: 261 MKVKLTDFGTAKILPEEPSNTADGKPYFDLYAKS-KSFVGTAEYVSPELLN--------D 311
Query: 305 NEQPFKIDVWSLGITVYAILYNVLPFWGETEFDTYNLI 342
N + D+W+ G +Y +L PF E+ T+ +
Sbjct: 312 NYTDSRCDIWAFGCILYQMLAGKPPFKAANEYLTFQKV 349
>YBR274w [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 527
Score = 68.9 bits (167), Expect = 1e-11
Identities = 70/263 (26%), Positives = 120/263 (45%), Gaps = 60/263 (22%)
Query: 133 MEMNVSKIRWECFVTSKLN-HPNVIQLLECLDSPYSDQIWLIQPLAVLGELQWSRESKFD 191
M ++ I E + SK + HPNV++L++C S + +W+I +A G+L E
Sbjct: 55 MGLSDKDITKEVVLQSKCSKHPNVLRLIDCNVS--KEYMWIILEMADGGDLFDKIEPDVG 112
Query: 192 LIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQ-GIIHRDLKPQNILLDPVYHSLR 250
+ FY QL S + YL + G+ HRD+KP+NILLD +L+
Sbjct: 113 VDSDVAQFYFQQLVSA--------------INYLHVECGVAHRDIKPENILLDK-NGNLK 157
Query: 251 ISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQPFK 310
++DFG + S+ KDG L+ ++ G+P + APE+ ++E +A +
Sbjct: 158 LADFG----LASQFRRKDGTLRVSMDQR-----GSPPYMAPEVL-YSEEGYYAD-----R 202
Query: 311 IDVWSLGITVYAILYNVLPF------------------------WGETEFDTYNLICHRQ 346
D+WS+GI ++ +L P+ W + EF NL+ +
Sbjct: 203 TDIWSIGILLFVLLTGQTPWELPSLENEDFVFFIENDGNLNWGPWSKIEFTHLNLL-RKI 261
Query: 347 LKPDVHNSSNIYGW-IHEYVVNR 368
L+PD + + +H +V+ R
Sbjct: 262 LQPDPNKRVTLKALKLHPWVLRR 284
>Hs7705748 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 835
Score = 68.9 bits (167), Expect = 1e-11
Identities = 76/269 (28%), Positives = 114/269 (42%), Gaps = 61/269 (22%)
Query: 65 HAQKFVNQYRIGERLGCGQFGTVYKGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYE 124
H +++ E +G G FG VYKG K+VAI KRY
Sbjct: 455 HFHLQLSEIEFHEIIGSGSFGKVYKGRCRNKIVAI---------------------KRYR 493
Query: 125 SISGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLL-ECLDSPYSDQIWLIQPLAVLGELQ 183
+ + + +V E + +LNHP VIQ + CL+ P Q ++ G L
Sbjct: 494 A---NTYCSKSDVDMFCREVSILCQLNHPCVIQFVGACLNDP--SQFAIVTQYISGGSL- 547
Query: 184 WSRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQG--QGIIHRDLKPQNIL 241
F L+ + K LD + + V D++ G++YL Q IIHRDL NIL
Sbjct: 548 ------FSLLHEQKRI----LDLQSKLIIAV--DVAKGMEYLHNLTQPIIHRDLNSHNIL 595
Query: 242 LDPVYHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSA 301
L H++ ++DFG S LQ L E + K G + APE+ F + +
Sbjct: 596 LYEDGHAV-VADFGESRF-----------LQSLDEDNMTKQPGNLRWMAPEV--FTQCTR 641
Query: 302 HASNEQPFKIDVWSLGITVYAILYNVLPF 330
+ K DV+S + ++ IL +PF
Sbjct: 642 YT-----IKADVFSYALCLWEILTGEIPF 665
>Hs4885583 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1354
Score = 68.9 bits (167), Expect = 1e-11
Identities = 78/314 (24%), Positives = 129/314 (40%), Gaps = 64/314 (20%)
Query: 37 LELGVISKTKIIERYVXXXXXXXXXQEEHAQKFVNQYRIGERLGCGQFGTVY--KGHTTG 94
L+ + K K I+ ++ + K Y + + +G G FG V + +T
Sbjct: 41 LDFPALRKNKNIDNFLSRYKDTINKIRDLRMK-AEDYEVVKVIGRGAFGEVQLVRHKSTR 99
Query: 95 KVVAIKQIYKKPMNSPFSMSLIMKTMKRYESISGDVLIMEMNVSKIRWE-CFVTSKLNHP 153
KV A MK + ++E I + + S WE + + N P
Sbjct: 100 KVYA------------------MKLLSKFEMI-------KRSDSAFFWEERDIMAFANSP 134
Query: 154 NVIQLLECL-DSPYSDQIWLIQPLAVLGELQWSRESKFDLIEQWKSFYRGQLDSVEEFAV 212
V+QL D Y + P L L S +D+ E+W FY ++
Sbjct: 135 WVVQLFYAFQDDRYLYMVMEYMPGGDLVNLM----SNYDVPEKWARFYTAEV-------- 182
Query: 213 KVLGDISNGLQYLQGQGIIHRDLKPQNILLDPVYHSLRISDFGCSLIVPSKLPFKDGRLQ 272
VL L + G IHRD+KP N+LLD H L+++DFG + + K+G ++
Sbjct: 183 -VLA-----LDAIHSMGFIHRDVKPDNMLLDKSGH-LKLADFGTCMKMN-----KEGMVR 230
Query: 273 DLFEKELNKIVGTPLFTAPELCNFAEGSAHASNEQPFKIDVWSLGITVYAILYNVLPFWG 332
+ VGTP + +PE+ G + E D WS+G+ +Y +L PF+
Sbjct: 231 ------CDTAVGTPDYISPEVLKSQGGDGYYGRE----CDWWSVGVFLYEMLVGDTPFYA 280
Query: 333 ETEFDTYNLICHRQ 346
++ TY+ I + +
Sbjct: 281 DSLVGTYSKIMNHK 294
>Hs16950619 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 1841
Score = 68.9 bits (167), Expect = 1e-11
Identities = 46/154 (29%), Positives = 81/154 (51%), Gaps = 26/154 (16%)
Query: 190 FDLIEQWKSFYRGQLDS----VEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNIL-LDP 244
+D+ E+ S + +D E +K + IS G++Y+ QGI+H DLKP+NI+ ++
Sbjct: 1464 YDIEERLGSLFERIIDEDFELTERECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNK 1523
Query: 245 VYHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHAS 304
+++ DFG + + + G L+ LF GTP F APE+ N+ E +A+
Sbjct: 1524 TGTRIKLIDFGLARRLENA-----GSLKVLF--------GTPEFVAPEVINY-EPIGYAT 1569
Query: 305 NEQPFKIDVWSLGITVYAILYNVLPFWGETEFDT 338
D+WS+G+ Y ++ + PF G+ + +T
Sbjct: 1570 -------DMWSIGVICYILVSGLSPFMGDNDNET 1596
>Hs16950615 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 1863
Score = 68.9 bits (167), Expect = 1e-11
Identities = 67/260 (25%), Positives = 118/260 (44%), Gaps = 66/260 (25%)
Query: 67 QKFVNQYRIGERLGCGQFGTVYKGHTTGKVVAIKQIYKKPMNSPFSMSLIMKTMKRYESI 126
QK + Y I ERLG G+FG V++ +++ +K F K Y +
Sbjct: 1458 QKVSDFYDIEERLGSGKFGQVFR--------LVEKKTRKVWAGKF--------FKAYSA- 1500
Query: 127 SGDVLIMEMNVSKIRWECFVTSKLNHPNVIQLLECLDSPYSDQIWLIQPLAVL--GELQW 184
IR E + + L+HP ++Q C+D+ + ++ ++ L ++ GEL
Sbjct: 1501 --------KEKENIRQEISIMNCLHHPKLVQ---CVDA-FEEKANIVMVLEIVSGGEL-- 1546
Query: 185 SRESKFDLIEQWKSFYRGQLDSVEEFAVKVLGDISNGLQYLQGQGIIHRDLKPQNIL-LD 243
++ + E +K + IS G++Y+ QGI+H DLKP+NI+ ++
Sbjct: 1547 -----------FERIIDEDFELTERECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVN 1595
Query: 244 PVYHSLRISDFGCSLIVPSKLPFKDGRLQDLFEKELNKIVGTPLFTAPELCNFAEGSAHA 303
+++ DFG + + + G L+ LF GTP F APE+ N+ E +A
Sbjct: 1596 KTGTRIKLIDFGLARRLENA-----GSLKVLF--------GTPEFVAPEVINY-EPIGYA 1641
Query: 304 SNEQPFKIDVWSLGITVYAI 323
+ D+WS+G+ Y +
Sbjct: 1642 T-------DMWSIGVICYIL 1654
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.320 0.137 0.411
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,833,243
Number of Sequences: 60738
Number of extensions: 1056768
Number of successful extensions: 6627
Number of sequences better than 1.0e-05: 909
Number of HSP's better than 0.0 without gapping: 1
Number of HSP's successfully gapped in prelim test: 909
Number of HSP's that attempted gapping in prelim test: 4988
Number of HSP's gapped (non-prelim): 1083
length of query: 467
length of database: 30,389,216
effective HSP length: 110
effective length of query: 357
effective length of database: 23,708,036
effective search space: 8463768852
effective search space used: 8463768852
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)