ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI7154 good OU KOG1568 Intracellular trafficking, secretion, and vesicular transport Mitochondrial inner membrane protease, subunit IMP2
r_klactVI7154 good OU KOG1568 Posttranslational modification, protein turnover, chaperones Mitochondrial inner membrane protease, subunit IMP2
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI7154 2493794 2493261 -178
(178 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YMR035w [OU] KOG1568 Mitochondrial inner membrane protease subun... 211 6e-55
SPBC336.13c [OU] KOG1568 Mitochondrial inner membrane protease s... 135 4e-32
7302349 [OU] KOG1568 Mitochondrial inner membrane protease subun... 112 4e-25
Hs14211845 [OU] KOG1568 Mitochondrial inner membrane protease su... 110 8e-25
At3g08980 [OU] KOG1568 Mitochondrial inner membrane protease sub... 98 7e-21
CE25490 [OU] KOG1568 Mitochondrial inner membrane protease subun... 95 6e-20
SPBC2D10.07c [O] KOG0171 Mitochondrial inner membrane protease s... 89 3e-18
Hs21450679 [O] KOG0171 Mitochondrial inner membrane protease sub... 83 2e-16
At1g29960_1 [O] KOG0171 Mitochondrial inner membrane protease su... 74 1e-13
At1g53530 [O] KOG0171 Mitochondrial inner membrane protease subu... 74 1e-13
7293105 [O] KOG0171 Mitochondrial inner membrane protease subuni... 72 4e-13
YMR150c [O] KOG0171 Mitochondrial inner membrane protease subuni... 63 2e-10
CE18529_1 [O] KOG0171 Mitochondrial inner membrane protease subu... 63 2e-10
At1g23470_1 [O] KOG0171 Mitochondrial inner membrane protease su... 62 4e-10
At2g30440 [O] KOG0171 Mitochondrial inner membrane protease subu... 50 2e-06
>YMR035w [OU] KOG1568 Mitochondrial inner membrane protease subunit IMP2
Length = 177
Score = 211 bits (536), Expect = 6e-55
Identities = 89/158 (56%), Positives = 121/158 (76%), Gaps = 1/158 (0%)
Query: 9 LRSAVITVSWIPVILTFTEHVCYVAKIEGSSMRPTLNPTDSFNNESDWVLLWKFNLKQAK 68
LR+ +I +SW+PV+LT +V ++A+++G+SM+PTLNP +DWVLLWKF +K
Sbjct: 11 LRNTLIAISWVPVLLTINNNVVHIAQVKGTSMQPTLNPQTE-TLATDWVLLWKFGVKNPS 69
Query: 69 NWKENDVVLFKSPSNPKKVYCKRVKGVQFDQVKTRSPYPKDTCLIPRNHLWVEGDNVYHS 128
N +D++LFK+P+NP+KVYCKRVKG+ FD + T+ PYPK +PR H+WVEGDN +HS
Sbjct: 70 NLSRDDIILFKAPTNPRKVYCKRVKGLPFDTIDTKFPYPKPQVNLPRGHIWVEGDNYFHS 129
Query: 129 VDSNNFGPISTGLALGKAVKIVWPPSRWSADLNMSEGR 166
+DSN FGPIS+GL +GKA+ IVWPPSRW DL +S GR
Sbjct: 130 IDSNTFGPISSGLVIGKAITIVWPPSRWGTDLKLSTGR 167
>SPBC336.13c [OU] KOG1568 Mitochondrial inner membrane protease subunit IMP2
Length = 180
Score = 135 bits (339), Expect = 4e-32
Identities = 66/153 (43%), Positives = 96/153 (62%), Gaps = 5/153 (3%)
Query: 3 NYGSYALRSAVITVSWIPVILTFTEHVCYVAKIEGSSMRPTLNPTDSFNNESDWVLLWKF 62
++ S ++ V W+PV++ +HV V IEG SM+P NP + + D VLLWK+
Sbjct: 10 SFKSVFFKNLVGITLWVPVLMFVEQHVVSVGTIEGRSMKPAFNPETNML-QRDRVLLWKW 68
Query: 63 NLKQAKNWKENDVVLFKSPSNPKKVYCKRVKGVQFDQVKTRSPYPKDTCLIPRNHLWVEG 122
N K++K DVV+ +SP NP+++ KRV GV++D +KTR P +P H+WVEG
Sbjct: 69 N----KDYKRGDVVILRSPENPEELLVKRVLGVEYDIMKTRPPKKLSLVPVPEGHVWVEG 124
Query: 123 DNVYHSVDSNNFGPISTGLALGKAVKIVWPPSR 155
D +HS+DSN FGP+STGL K + I++P SR
Sbjct: 125 DEQFHSIDSNKFGPVSTGLITAKVIAILFPFSR 157
>7302349 [OU] KOG1568 Mitochondrial inner membrane protease subunit IMP2
Length = 171
Score = 112 bits (279), Expect = 4e-25
Identities = 57/138 (41%), Positives = 84/138 (60%), Gaps = 5/138 (3%)
Query: 19 IPVILTFTEHVCYVAKIEGSSMRPTLNPTDSFNNESDWVLLWKFNLKQAKNWKENDVVLF 78
+P+ +TF + V YVA+++G SM+P LNP +E D+V L ++ ++ + D++
Sbjct: 14 LPLGVTFLDCVGYVARVDGISMQPALNPVP---DEKDYVFLLRWGTHNSQV-ERGDIISL 69
Query: 79 KSPSNPKKVYCKRVKGVQFDQVKTRSPYPKDTCLIPRNHLWVEGDNVYHSVDSNNFGPIS 138
SP +P + KRV G+Q D V T Y + +P H WVEGD+ HS+DSN FGP++
Sbjct: 70 ISPKDPAQKIIKRVVGLQGDVVSTLG-YKHEIVRVPEGHCWVEGDHTGHSMDSNTFGPVA 128
Query: 139 TGLALGKAVKIVWPPSRW 156
GL +AV IVWPP RW
Sbjct: 129 LGLMSARAVAIVWPPERW 146
>Hs14211845 [OU] KOG1568 Mitochondrial inner membrane protease subunit IMP2
Length = 175
Score = 110 bits (276), Expect = 8e-25
Identities = 63/143 (44%), Positives = 89/143 (62%), Gaps = 14/143 (9%)
Query: 19 IPVILTFTEHVCYVAKIEGSSMRPTLNPTDSFNNESDWVLLWKFNLKQAKNWK--ENDVV 76
+PV +TF + V VA++EG+SM+P+LNP S SD VLL N + +N++ D+V
Sbjct: 23 VPVAVTFLDRVACVARVEGASMQPSLNPGGS--QSSDVVLL---NHWKVRNFEVHRGDIV 77
Query: 77 LFKSPSNPKKVYCKRVKGVQFDQVKT---RSPYPKDTCLIPRNHLWVEGDNVYHSVDSNN 133
SP NP++ KRV ++ D V+T ++ Y K +PR H+WVEGD+ HS DSN+
Sbjct: 78 SLVSPKNPEQKIIKRVIALEGDIVRTIGHKNRYVK----VPRGHIWVEGDHHGHSFDSNS 133
Query: 134 FGPISTGLALGKAVKIVWPPSRW 156
FGP+S GL A I+WPP RW
Sbjct: 134 FGPVSLGLLHAHATHILWPPERW 156
>At3g08980 [OU] KOG1568 Mitochondrial inner membrane protease subunit IMP2
Length = 154
Score = 97.8 bits (242), Expect = 7e-21
Identities = 53/135 (39%), Positives = 77/135 (56%), Gaps = 6/135 (4%)
Query: 23 LTFTEHVCYVAKIEGSSMRPTLNPTDSFNNESDWVLLWKFNLKQAKNWKENDVVLFKSPS 82
LT ++ C V + G SM PT NP + + D+VL+ KF LK K + DVV+F SP+
Sbjct: 22 LTISDRCCSVVPVRGDSMSPTFNPQRN-SYLDDYVLVDKFCLKDYK-FARGDVVVFSSPT 79
Query: 83 NPKKVYCKRVKGVQFDQVKTRSPYPKDTCLIPRNHLWVEGDNVYHSVDSNNFGPISTGLA 142
+ Y KR+ G+ + + + +D +P H WVEGDN S+DS +FGPI GL
Sbjct: 80 HFGDRYIKRIVGMPGEWISSS----RDVIRVPEGHCWVEGDNKTSSLDSRSFGPIPLGLI 135
Query: 143 LGKAVKIVWPPSRWS 157
G+ +++WPP R S
Sbjct: 136 QGRVTRVMWPPQRIS 150
>CE25490 [OU] KOG1568 Mitochondrial inner membrane protease subunit IMP2
Length = 152
Score = 94.7 bits (234), Expect = 6e-20
Identities = 53/136 (38%), Positives = 78/136 (56%), Gaps = 4/136 (2%)
Query: 21 VILTFTEHVCYVAKIEGSSMRPTLNPTDSFNNESDWVLLWKFNLKQAKNWKENDVVLFKS 80
V+ TF + V + A++ G+SM+PTL D+ + D V L +NL + ++ F S
Sbjct: 16 VVFTFFDVVGHPAQVVGNSMQPTLQGGDARWYKRDIVWLSTWNLYKCS---PGTILTFVS 72
Query: 81 PSNPKKVYCKRVKGVQFDQVKTRSPYPKDTCLIPRNHLWVEGDNVYHSVDSNNFGPISTG 140
P +P V+ KRV V+ V+ P+ IP+ H W+EGDN H DSN +GP+ST
Sbjct: 73 PRDPDAVHIKRVTAVENAIVRPEKR-PELITDIPKGHYWMEGDNPEHRHDSNVYGPVSTS 131
Query: 141 LALGKAVKIVWPPSRW 156
L G+A I+WPP+RW
Sbjct: 132 LVKGRATHIIWPPNRW 147
>SPBC2D10.07c [O] KOG0171 Mitochondrial inner membrane protease subunit IMP1
Length = 157
Score = 89.0 bits (219), Expect = 3e-18
Identities = 50/156 (32%), Positives = 78/156 (49%), Gaps = 8/156 (5%)
Query: 5 GSYALRSAVITVSWIPVILTFTEHVCYVAKIEGSSMRPTLNPTDSFNNESDWVLLWKFNL 64
G + + AV+ ++ + E++ V G SM PTLN F VLL K +
Sbjct: 3 GMFRIPIAVVQIA--AFVHQIHEYLFQVQMTSGPSMMPTLNSGGEF------VLLDKLHG 54
Query: 65 KQAKNWKENDVVLFKSPSNPKKVYCKRVKGVQFDQVKTRSPYPKDTCLIPRNHLWVEGDN 124
+ A++ DVV+ PS+ K+ CKR+ G+ D + IP H+W+ GDN
Sbjct: 55 RFARSCSVGDVVVSAKPSDSKQHVCKRIIGMPGDTIYVDPTSSNKKITIPLGHVWLAGDN 114
Query: 125 VYHSVDSNNFGPISTGLALGKAVKIVWPPSRWSADL 160
+ HS+DS N+GP+ GL K + VWP W +++
Sbjct: 115 IAHSLDSRNYGPVPMGLIKAKVIARVWPHPHWMSNI 150
>Hs21450679 [O] KOG0171 Mitochondrial inner membrane protease subunit IMP1
Length = 166
Score = 82.8 bits (203), Expect = 2e-16
Identities = 48/131 (36%), Positives = 72/131 (54%), Gaps = 12/131 (9%)
Query: 27 EHVCYVAKIEGSSMRPTLNPTDSFNNESDWVLLWKFNL-KQAKNWKENDVVLFKSPSNPK 85
E+V V G SM PT+ +D +++ NL + + D+V+ KSPS+PK
Sbjct: 28 EYVGGVVMCSGPSMEPTIQNSD---------IVFAENLSRHFYGIQRGDIVIAKSPSDPK 78
Query: 86 KVYCKRVKGVQFDQVKTRSP--YPKDTCLIPRNHLWVEGDNVYHSVDSNNFGPISTGLAL 143
CKRV G++ D++ T SP + K +P H+W+EGDN+ +S DS +GPI GL
Sbjct: 79 SNICKRVIGLEGDKILTTSPSDFFKSHSYVPMGHVWLEGDNLQNSTDSRCYGPIPYGLIR 138
Query: 144 GKAVKIVWPPS 154
G+ +WP S
Sbjct: 139 GRIFFKIWPLS 149
>At1g29960_1 [O] KOG0171 Mitochondrial inner membrane protease subunit IMP1
Length = 153
Score = 73.9 bits (180), Expect = 1e-13
Identities = 44/144 (30%), Positives = 76/144 (52%), Gaps = 11/144 (7%)
Query: 8 ALRSAVITVSWIPVILTFTEHVCYVAKIEGSSMRPTLNPTDSFNNESDWVLLWKFNLKQA 67
A++S V+ + T ++ ++A G SM PTL+P+ + VLL + K+
Sbjct: 16 AMKSGVLLAKLYCFLHVTTNYLGFMAYAYGPSMTPTLHPSGN-------VLLAERISKRY 68
Query: 68 KNWKENDVVLFKSPSNPKKVYCKRVKGVQFDQVK----TRSPYPKDTCLIPRNHLWVEGD 123
+ D+V+ +SP NP K KRV G++ D + +R T ++P+ H++V+GD
Sbjct: 69 QKPSRGDIVVIRSPENPNKTPIKRVIGIEGDCISFVIDSRKSDESQTIVVPKGHVFVQGD 128
Query: 124 NVYHSVDSNNFGPISTGLALGKAV 147
++S DS NFG + GL G+ +
Sbjct: 129 YTHNSRDSRNFGTVPYGLIQGRVL 152
>At1g53530 [O] KOG0171 Mitochondrial inner membrane protease subunit IMP1
Length = 168
Score = 73.6 bits (179), Expect = 1e-13
Identities = 44/144 (30%), Positives = 75/144 (51%), Gaps = 11/144 (7%)
Query: 8 ALRSAVITVSWIPVILTFTEHVCYVAKIEGSSMRPTLNPTDSFNNESDWVLLWKFNLKQA 67
A + I ++ ++ ++ + G SM PTLN T V+L + +
Sbjct: 17 AFENVSIVAKFLCLLHVTDRYIISTTHVHGPSMLPTLNLTGD-------VILAEHLSHRF 69
Query: 68 KNWKENDVVLFKSPSNPKKVYCKRVKGVQFDQVK-TRSPYPKD---TCLIPRNHLWVEGD 123
DVVL +SP +PK++ KR+ G++ D++ + P D + L+P+ H+W++GD
Sbjct: 70 GKIGLGDVVLVRSPRDPKRMVTKRILGLEGDRLTFSADPLVGDASVSVLVPKGHVWIQGD 129
Query: 124 NVYHSVDSNNFGPISTGLALGKAV 147
N+Y S DS +FGP+ L GKA+
Sbjct: 130 NLYASTDSRHFGPVPYSLIEGKAL 153
>7293105 [O] KOG0171 Mitochondrial inner membrane protease subunit IMP1
Length = 166
Score = 72.0 bits (175), Expect = 4e-13
Identities = 47/156 (30%), Positives = 72/156 (46%), Gaps = 24/156 (15%)
Query: 15 TVSWIPVILTFTEHVCYVAKIEGSSMRPTLNPTDSFNNESDWVLLWKFNLKQAKNWKEND 74
TV++ + E++ +G SM PTL+ SD VLL + K + ++ D
Sbjct: 14 TVAYAAITHCTFEYIGDFVLCKGPSMEPTLH--------SDNVLLTERLSKHWRTYQPGD 65
Query: 75 VVLFKSPSNPKKVYCKRVKGVQFDQVKTRSPYPKDTCL----------------IPRNHL 118
+V+ SP + CKR+ V DQV + P P + +PR H+
Sbjct: 66 IVIAISPIKADQFICKRIVAVSGDQVLIQKPIPIEAEFSGNSDDKKKPVMVKDYVPRGHV 125
Query: 119 WVEGDNVYHSVDSNNFGPISTGLALGKAVKIVWPPS 154
W+EGDN +S DS +GPI GL + + +WP S
Sbjct: 126 WIEGDNKGNSSDSRYYGPIPVGLIRSRVLCRIWPIS 161
>YMR150c [O] KOG0171 Mitochondrial inner membrane protease subunit IMP1
Length = 190
Score = 62.8 bits (151), Expect = 2e-10
Identities = 49/156 (31%), Positives = 69/156 (43%), Gaps = 28/156 (17%)
Query: 6 SYALRSAVITVSWIPVILTFTEHVCYVAKIEGSSMRPTLNPTDSFNNESDWVLLWKFNLK 65
SYA+RS FTE G SM PTL+ T+ D+V + K N +
Sbjct: 14 SYAIRSLCFLHIIHMYAYEFTE-------TRGESMLPTLSATN------DYVHVLK-NFQ 59
Query: 66 QAKNWKENDVVLFKSPSNPKKVYCKRVKGVQFDQV----KTRSPYPKDTCL--------- 112
+ K D ++ P++P CKRV G+ D V T Y D +
Sbjct: 60 NGRGIKMGDCIVALKPTDPNHRICKRVTGMPGDLVLVDPSTIVNYVGDVLVDEERFGTYI 119
Query: 113 -IPRNHLWVEGDNVYHSVDSNNFGPISTGLALGKAV 147
+P H+WV GDN+ HS+DS + + GL +GK V
Sbjct: 120 KVPEGHVWVTGDNLSHSLDSRTYNALPMGLIMGKIV 155
>CE18529_1 [O] KOG0171 Mitochondrial inner membrane protease subunit IMP1
Length = 131
Score = 62.8 bits (151), Expect = 2e-10
Identities = 41/125 (32%), Positives = 64/125 (50%), Gaps = 13/125 (10%)
Query: 37 GSSMRPTLNPTDSFNNESDWVLLWKFNLKQAKNWKENDVVLFKSPSNPKKVYCKRVKGVQ 96
G SM PT++ + D VL +F+++ KN + D+V +P PK++ CKR+ +
Sbjct: 6 GPSMHPTIH-------DGDLVLAERFSIRN-KNVQVGDIVGCVNPQKPKELLCKRIAAKE 57
Query: 97 FDQVKTRSPYPKDTCLIPRNHLWVEGDNVYHSVDSNNFGPISTGLALGKAVKIVWPPSR- 155
D V T P +P H+++ GDN S DS +FGP+ L + +WPP R
Sbjct: 58 GDPV-TSHLLPSGR--VPIGHVFLRGDNGPVSTDSRHFGPVPEALVQIRLSLRIWPPERA 114
Query: 156 -WSAD 159
W +D
Sbjct: 115 GWISD 119
>At1g23470_1 [O] KOG0171 Mitochondrial inner membrane protease subunit IMP1
Length = 175
Score = 62.0 bits (149), Expect = 4e-10
Identities = 32/87 (36%), Positives = 50/87 (56%), Gaps = 4/87 (4%)
Query: 65 KQAKNWKENDVVLFKSPSNPKKVYCKRVKGVQFDQVK-TRSPYPKD---TCLIPRNHLWV 120
K+ + D+V+ +SP NP K KRV GV+ D + P D T ++P+ H++V
Sbjct: 87 KRYQKPSRGDIVVIRSPENPNKTPIKRVVGVEGDCISFVIDPVKSDESQTIVVPKGHVFV 146
Query: 121 EGDNVYHSVDSNNFGPISTGLALGKAV 147
+GD ++S DS NFGP+ GL G+ +
Sbjct: 147 QGDYTHNSRDSRNFGPVPYGLIQGRVL 173
>At2g30440 [O] KOG0171 Mitochondrial inner membrane protease subunit IMP1
Length = 250
Score = 49.7 bits (117), Expect = 2e-06
Identities = 41/168 (24%), Positives = 69/168 (40%), Gaps = 37/168 (22%)
Query: 19 IPVILTFTEHVCYVAKIEGSSMRPTLNPTDSFNNESDWVLLWKFNLKQAKNWKENDVVLF 78
+ V + F + I +SM PTL+ D E K + +D+V+F
Sbjct: 74 VTVSILFRSALAEPKSIPSTSMYPTLDKGDRVMAEKVSYFFRKPEV--------SDIVIF 125
Query: 79 KSPS----------NPKKVYCKRVKGVQFDQVKTRS-------------------PYPKD 109
K+P + V+ KR+ + D V+ R Y +
Sbjct: 126 KAPPILLEYPEYGYSSNDVFIKRIVASEGDWVEVRDGKLFVNDIVQEEDFVLEPMSYEME 185
Query: 110 TCLIPRNHLWVEGDNVYHSVDSNNFGPISTGLALGKAVKIVWPPSRWS 157
+P+ +++V GDN S DS+N+GP+ +G++V WPPS+ S
Sbjct: 186 PMFVPKGYVFVLGDNRNKSFDSHNWGPLPIENIVGRSVFRYWPPSKVS 233
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.318 0.134 0.428
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,286,415
Number of Sequences: 60738
Number of extensions: 531106
Number of successful extensions: 985
Number of sequences better than 1.0e-05: 15
Number of HSP's better than 0.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 958
Number of HSP's gapped (non-prelim): 15
length of query: 178
length of database: 30,389,216
effective HSP length: 99
effective length of query: 79
effective length of database: 24,376,154
effective search space: 1925716166
effective search space used: 1925716166
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)